FedInvent™ Patent Applications
Application Details for Thursday, August 17, 2023
This page was updated on Saturday, August 19, 2023 at 01:20 AM GMT
Department of Health and Human Services (HHS)
| US 20230255186 | Shultz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Leonard D. Shultz (Bar Harbor, Maine) |
| ABSTRACT | The present disclosure provides a transgenic, immunocompromised mouse engineered to express a human angiotensin converting enzyme 2 (huACE2) sequence. The huACE2 sequence may be operably linked to a human keratin 18 (hKRT18) promoter or the endogenous mouse angiotensin converting enzyme 2 (mACE2) promoter. Transgenic immunocompromised mice of the present disclosure may be utilized in methods of evaluating a test agent for reducing or preventing SARS-CoV-2 infection. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 18/016133 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) Original (OR) Class A01K 2207/12 (20130101) A01K 2207/15 (20130101) A01K 2217/072 (20130101) A01K 2227/105 (20130101) A01K 2267/0337 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) C12N 15/52 (20130101) Enzymes C12Y 304/17023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255478 | Abramoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael D. Abramoff (University Heights, Iowa); Meindert Niemeijer (Iowa City, Iowa); Xiayu Xu (Iowa City, Iowa); Milan Sonka (Coralville, Iowa); Joseph M. Reinhardt (Iowa City, Iowa) |
| ABSTRACT | The methods and systems provided can automatically determine an Arteriolar-to-Venular diameter Ratio, AVR, in blood vessels, such as retinal blood vessels and other blood vessels in vertebrates. The AVR is an important predictor of increases in the risk for stroke, cerebral atrophy, cognitive decline, and myocardial infarct. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/185704 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) Original (OR) Class A61B 3/0016 (20130101) A61B 3/0058 (20130101) A61B 3/1225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255493 | HILLMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth M.C. HILLMAN (New York, New York); Sean A. BURGESS (New York, New York) |
| ABSTRACT | Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM). |
| FILED | Friday, April 14, 2023 |
| APPL NO | 18/134805 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0064 (20130101) Original (OR) Class A61B 5/0066 (20130101) A61B 5/0071 (20130101) A61B 5/0073 (20130101) A61B 5/0075 (20130101) A61B 5/0088 (20130101) A61B 5/444 (20130101) A61B 5/445 (20130101) A61B 2562/0238 (20130101) A61B 2562/0242 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/457 (20130101) G01J 3/2889 (20130101) Optical Elements, Systems, or Apparatus G02B 23/2476 (20130101) G02B 26/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255516 | ARDELL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Laurence ARDELL (Encino, California); Corey SMITH (University Heights, Ohio); Kalyanam SHIVKUMAR (Los Angeles, California) |
| ABSTRACT | The present invention provides a device and methods of use related to the use of electrodes to continuously detect the presence and abundance of various biochemical compounds of interest with high spatial and temporal resolution, comprising the steps of inserting one or more electrodes in one or more locations selected from the group consisting of a tissue, an organ, a neural structure, a lymphatic vessel, a lymphatic node, an extravascular fluid compartment, and a peripheral blood vessel; applying a voltage scan to the electrode; an detecting a current indicative of the presence and abundance of the compound. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 18/002995 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/263 (20210101) A61B 5/14503 (20130101) Original (OR) Class A61B 2562/0214 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255552 | Inan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Omer Inan (Atlanta, Georgia); Samer Mabrouck (Atlanta, Georgia) |
| ABSTRACT | An exemplary embodiment of the present disclosure provides a system for assessing joint health comprising a joint sensor configured to measure at least one non-acoustic characteristic of a joint during movement; a bioimpedance sensor configured to measure bioimpedance of a joint structure exposed to electrical current at a plurality of frequencies; a processor; and a memory, the memory comprising instructions that, when executed by the processor, cause the processor to provide an assessment of joint health through interpretation of measurements from the joint sensor and the bioimpedance sensor. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 18/012451 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/0537 (20130101) A61B 5/1114 (20130101) A61B 5/1121 (20130101) A61B 5/1126 (20130101) A61B 5/4595 (20130101) Original (OR) Class A61B 5/4878 (20130101) A61B 5/6829 (20130101) A61B 2562/06 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255597 | O'Reilly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sunnybrook Research Institute (Toronto, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Meaghan Anne O'Reilly (Toronto, Canada); Kullervo Henrik Hynynen (Toronto, Canada) |
| ABSTRACT | A system and method for controlling the delivery of ultrasound energy to a subject is provided. In particular, such a system and method are capable of safely disrupting the blood-brain barrier. Ultrasound energy is delivered to produce cavitation of an ultrasound contrast agent at a selected pressure value. An acoustic signal is acquired following cavitation, from which a signal spectrum is produced. The signal spectrum is analyzed for the presence of harmonics, such as subharmonics or ultraharmonics. When subharmonics or ultraharmonics are present, the pressure value is decreased for subsequent sonications. If a previous sonication resulted in no subharmonics or ultraharmonics being generated, then the pressure value may be increased. In this manner, the blood-brain barrier can be advantageously disrupted while mitigating potentially injurious effects of the sonication. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/903999 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) Original (OR) Class A61B 8/0808 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) A61N 2007/0095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255874 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | X.Z. Shawn Xu (Ann Arbor, Michigan); Jianfeng Liu (Wuhan, China PRC) |
| ABSTRACT | The present disclosure relates to compositions capable of absorbing UVA and UVB light. In particle, the present disclosure relates to UV screening compositions comprising at least a portion of LITE-1 polypeptides which are capable of absorbing UV light (e.g., UV-A and/or UV-B light). |
| FILED | Thursday, February 16, 2023 |
| APPL NO | 18/169971 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/64 (20130101) Original (OR) Class A61K 9/0014 (20130101) A61K 38/1767 (20130101) A61K 2800/10 (20130101) A61K 2800/86 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255888 | BALU-IYER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sathy V. BALU-IYER (Amherst, New York); Nhan Hanh NGUYEN (Amherst, New York); Dominique WEEKS (Amherst, New York); Vincent CHAK (Amherst, New York); Milagros GONZALEZ (Amherst, New York) |
| ABSTRACT | Disclosed are methods of preparing liposomes without size exclusion steps resulting in small sized liposomes exhibiting narrow size distribution and compositions of same. The methods utilize liposome formation from lyso-PS, PS, and PC as the only phospholipids. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 18/003904 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1278 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255948 | Morser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of The Leland Stanford Junior University (Stanford, California); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael J. Morser (San Francisco, California); Lawrence L.K Leung (Hillsborough, California); Timothy Myles (Sunnyvale, California) |
| ABSTRACT | Methods for treating cancer using combination therapy with an anti-coagulant and a B-Raf inhibitor and/or a mitogen-activated protein kinase (MEK) inhibitor are disclosed. The anti-coagulant may be a direct inhibitor of thrombin or an indirect inhibitor of thrombin, such as an inhibitor of factor Xa, factor XIa, or other coagulation factors. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 18/014971 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4439 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255950 | Oyelere et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adegboyega K. Oyelere (Atlanta, Georgia); Verjine Khodaverdian (Atlanta, Georgia); Subhasish Tapadar (Atlanta, Georgia) |
| ABSTRACT | Compositions and methods for inhibiting histone lysine demethylases are provided. Several new DFP-based KDM inhibitors which alter the velocity of HP1-mediated heterochromatin gene repression are provided. |
| FILED | Monday, April 10, 2023 |
| APPL NO | 18/297974 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4439 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 401/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255951 | DALVI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (AUSTIN, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maithili P. DALVI (Dallas, Texas); Elisabeth D. MARTINEZ (Dallas, Texas); John D. MINNA (Dallas, Texas); Juan BAYO-FINA (Dallas, Texas); Amit DAS (Dallas, Texas) |
| ABSTRACT | Disclosed are methods for the use of Jumonji C demethylase inhibitors for the radiosensitization of cancers cells and the treatment and prevention of chemotherapy resistance in cancer. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055045 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/44 (20130101) A61K 31/55 (20130101) A61K 31/282 (20130101) A61K 31/337 (20130101) A61K 31/444 (20130101) Original (OR) Class A61K 33/243 (20190101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255954 | Demehri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shadmehr Demehri (Charlestown, Massachusetts); Jong Ho Park (Boston, Massachusetts) |
| ABSTRACT | Described herein are methods and compositions for treating cancer, fibrosis, and inflammation, and reducing risk of developing cancer, fibrosis, and inflammation, using small molecule inhibitors of IL-33, i.e., pitavastatin calcium, tropisetron, ammonium glycyrrhizinate, ticagrelor, and cetrimonium bromide. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 18/014580 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 31/14 (20130101) A61K 31/46 (20130101) A61K 31/47 (20130101) Original (OR) Class A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255958 | Pulley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jill M. Pulley (Nashville, Tennessee); Rebecca N. Jerome (Nashville, Tennessee); Dawn B. Beaulieu (Nashville, Tennessee); Jana K. Shirey-Rice (Brentwood, Tennessee); Nicole M. Zaleski (Nashville, Tennessee) |
| ABSTRACT | Disclosed herein are methods for treating or reducing symptoms of a gastrointestinal motility disorder in a subject. The methods include administering to the subject a therapeutically effective amount of a sodium channel blocker compound. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 18/001180 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255970 | EISINGER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Tzipora Sarah Karin EISINGER (Philadelphia, Pennsylvania); Gabrielle CIOTTI (Philadelphia, Pennsylvania); Ashley M. FULLER (Philadelphia, Pennsylvania); Mohammad ROHBAN (Cambridge, Massachusetts); Anne Carpenter VAN DYK (Cambridge, Massachusetts); Shantanu SINGH (Cambridge, Massachusetts) |
| ABSTRACT | The present invention features compositions and methods for treating proliferative diseases such as cancer (e.g., sarcoma, pancreas, prostate, head and neck, liver, and breast cancer) that inhibit the growth of NF-κB and/or Hippo associated neoplasias. |
| FILED | Thursday, August 12, 2021 |
| APPL NO | 18/020827 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255988 | GIBSON |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); BURKE NEUROLOGICAL INSTITUTE (White Plains, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York); BURKE NEUROLOGICAL INSTITUTE (White Plains, New York) |
| INVENTOR(S) | Gary GIBSON (Larchmont, New York) |
| ABSTRACT | A method for treating a subject having or likely to develop a neurodegenerative disease, wherein the subject is administered a pharmaceutically effective amount of a compound within the generic structure (1) wherein R1 is either —R or —SR, wherein R is a hydrocarbon group containing 1-20 carbon atoms and optionally containing one or more heteroatoms selected from oxygen, nitrogen, and sulfur; and R2 is selected from the group consisting of —OR′, —OPO32−, and —OC(O)R′, wherein R′ is a hydrogen atom or a hydrocarbon group containing 1-6 carbon atoms; and wherein Formula (1) may include pharmaceutically acceptable salts, solvates, and polymorphs thereof, and wherein the subject may be identified as positive, before or during treatment, for at least one marker, including, for example, amyloid plaques, neurofibrillary tangles, decline in brain glucose metabolism, decline in thiamine diphosphate-dependent enzyme activity, and increase in advanced glycation end products. |
| FILED | Thursday, July 29, 2021 |
| APPL NO | 18/018417 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/675 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255993 | Lothstein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paradox Pharmaceuticals, Inc. (Memphis, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leonard Lothstein (Eads, Tennessee); Judith Soberman (Eads, Tennessee); Tiffany N. Seagroves (Memphis, Tennessee) |
| ABSTRACT | The present invention relates to compositions comprising at least one of pivarubicin and benzarubicin, or a pharmaceutically acceptable salt thereof, and methods for using the compositions in the treatment of triple negative breast cancer (TNBC) by administering an effective amount of the compositions to a subject. In some instances, the subject is a mammal, including at least one of human, feline, and canine mammals. |
| FILED | Friday, April 21, 2023 |
| APPL NO | 18/304606 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) Original (OR) Class A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/14 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255998 | Pavel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ana Brandusa Pavel (New York, New York); Joshua David Campbell (Sharon, Massachusetts); Marc Elliott Lenburg (Brookline, Massachusetts); Avrum Elliot Spira (Newton, Massachusetts) |
| ABSTRACT | The methods and assays described herein relate to detection, diagnosis, and treatment of lung cancer, e.g., by detecting the level of expression of certain miRNAs described herein and/or by therapeutically increasing the level of those miRNAs. |
| FILED | Tuesday, July 19, 2022 |
| APPL NO | 17/867929 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6886 (20130101) C12Q 2539/10 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256015 | CAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | YU-QING CAO (St. Louis, Missouri); ZHIYU ZHANG (St. Louis, Missouri); RONG HU (St. Louis, Missouri); JINTAO ZHANG (St. Louis, Missouri); MEGAN E. CLOUD (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of compositions and methods of treating or preventing various headache disorders or neuropathic pain by increasing the number of Treg cells in a subject. In particular, low dose IL-2, rapamycin, statin or Treg cell administration are shown to be useful in treating or preventing headache or neuropathic pain. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/787026 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/2013 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256022 | ANVERSA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AAL SCIENTIFICS, INC. (New York, New York) |
| ASSIGNEE(S) | AAL SCIENTIFICS, INC. (New York, New York) |
| INVENTOR(S) | Piero ANVERSA (New York, New York); Annarosa LERI (New York, New York) |
| ABSTRACT | Disclosed herein are compositions comprising myogenic bone marrow cells that are c-kit positive. Such compositions are useful for treating cardiac diseases or disorders. Also disclosed herein are methods of producing myogenic bone marrow cells are c-kit positive. Further disclosed are cardiopoietic genes having enhanced expression in c-kit positive myogenic bone marrow cells. |
| FILED | Monday, December 19, 2022 |
| APPL NO | 18/084206 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 5/0663 (20130101) C12N 2501/727 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256034 | NAGLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF CHICAGO (CHICAGO, Illinois); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (STANFORD, California) |
| ASSIGNEE(S) | THE UNIVERSITY PF CHICAGO (CHICAGO, Illinois); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (STANFORD, California) |
| INVENTOR(S) | Cathryn R. NAGLER (Chicago, Illinois); Kari NADEAU (Stanford, California); Riyue BAO (Chicago, Illinois); Lauren Anders HESSER (Chicago, Illinois) |
| ABSTRACT | The current disclosure provides methods and compositions for treating autoimmune conditions, including allergic conditions such as food allergy. Certain aspects of the disclosure relate to methods for treatment of food allergy comprising administering a composition comprising Phascolarctobacterium faecium and/or Ruminococcus bromii. In some aspects, disclosed are compositions comprising isolated, lyophilized bacteria such as Phascolarctobacterium faecium and/or Ruminococcus bromii. |
| FILED | Thursday, July 22, 2021 |
| APPL NO | 18/006385 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/741 (20130101) Original (OR) Class A61K 39/35 (20130101) A61K 47/36 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256053 | BRISCOE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | David M. BRISCOE (Sharon, Massachusetts); Michael KLAGSBRUN (Newton, Massachusetts); Sarah BRUNEAU (Boston, Massachusetts); Nora KOCHUPURAKKAL (Boston, Massachusetts); Hironao NAKAYAMA (Boston, Massachusetts) |
| ABSTRACT | The methods and uses described herein relate to the modulation of the immune system by modulation of Sema3F levels and/or activity, e.g. suppressing allograft rejection or inflammation by administering a Sema3F agonist or increasing an immune response by administering a Sema3F inhibitor. |
| FILED | Thursday, April 06, 2023 |
| APPL NO | 18/296510 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) A61K 38/482 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/28 (20130101) C07K 16/2803 (20130101) C07K 2317/76 (20130101) Enzymes C12Y 304/21 (20130101) C12Y 304/21075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256067 | Hodge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GLOBEIMMUNE, INC. (Louisville, Colorado); The USA, as represented bye Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Hodge (Kensington, Maryland); Jeffrey Schlom (Potomac, Maryland); Alex Franzusoff (Los Altos, California) |
| ABSTRACT | Disclosed are immunotherapeutic compositions and the concurrent use of combinations of such compositions for the improved induction of therapeutic immune responses and/or for the prevention, amelioration and/or treatment of disease, including, but not limited to, cancer and infectious disease. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/158800 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/00117 (20180801) A61K 39/001102 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/001151 (20180801) A61K 39/001152 (20180801) A61K 39/001156 (20180801) A61K 39/001157 (20180801) A61K 39/001162 (20180801) A61K 39/001164 (20180801) A61K 39/001168 (20180801) A61K 39/001182 (20180801) A61K 39/001184 (20180801) A61K 39/001186 (20180801) A61K 39/001188 (20180801) A61K 39/001191 (20180801) A61K 39/001192 (20180801) A61K 39/001194 (20180801) A61K 39/001195 (20180801) A61K 2039/523 (20130101) A61K 2039/55522 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256072 | MOE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Omvax, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory MOE (Oakland, California); Serena GIUNTINI (Walnut Creek, California) |
| ABSTRACT | The disclosure provides compositions, and methods of use thereof, for vaccines for treatment of gonococcal and/or meningococcal infection, comprising native outer membrane vesicle (NOMV) derived from bacteria containing a gonococcal protein that is a lipoprotein or is modified to be a lipoprotein. Also provided are meningococcal strains containing a gene encoding a gonococcal protein that is a lipoprotein or is modified to be a lipoprotein. |
| FILED | Friday, April 21, 2023 |
| APPL NO | 18/305164 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/095 (20130101) Original (OR) Class A61K 41/0047 (20130101) A61K 2039/523 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 9/1025 (20130101) C12N 15/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256080 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xuefei Huang (Okemos, Michigan); Suttipun Sungsuwan (Bangkok, Thailand); Shivangi Chugh (East Lansing, Michigan); Vilma Yuzbasiyan-Gurkan (Ann Arbor, Michigan); Cheryl L. Swenson (Okemos, Michigan) |
| ABSTRACT | Provided herein are vaccine composition comprising a bovine leukemia virus (BLV) antigen conjugated to a capsid, wherein the capsid comprises wild type or native sequence. Provided herein are also vaccine composition comprising a BLV antigen conjugated to a capsid, wherein said capsid comprises at least one mutation, such as a non-natural mutation. Such compositions are useful in the treatment and prevention of BLV infection and associated sequelae, e.g. cancer, immunosuppressive, and inflammatory diseases. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/712600 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Original (OR) Class A61K 39/0275 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256115 | GARCIA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andres J. GARCIA (Atlanta, Georgia); Maria M. CORONEL (Atlanta, Georgia); Haval SHIRWAN (Columbia, Missouri); Esma S. YOLCU (Columbia, Missouri) |
| ABSTRACT | Disclosed are PD-L1 presenting compositions. The compositions may be used to effect immunomodulation in a variety of contexts. The compositions may be used to decrease rates of transplant rejection, including pancreatic islet cell transplantation. The compositions are useful for the treatment of type 1 diabetes. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 18/015232 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/22 (20130101) A61K 47/60 (20170801) A61K 47/6903 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256121 | Larson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven Larson (New York, New York); Darren Veach (New York, New York); Sarah Cheal (New York, New York); Ouathek Ouerfelli (New York, New York); Guangbin Yang (New York, New York); Nai-Kong Cheung (New York, New York); Brian Santich (New York, New York); Hong Xu (New York, New York) |
| ABSTRACT | The present disclosure provides compositions and methods for the detection and treatment of cancer. Specifically, the compositions of the present technology include novel compounds that may be complexed with a radioisotope. Also disclosed herein are methods of the using the DOTA-haptens of the present technology in diagnostic imaging as well as pretargeted radioimmunotherapy. |
| FILED | Monday, June 28, 2021 |
| APPL NO | 18/003659 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6893 (20170801) A61K 51/065 (20130101) Original (OR) Class A61K 51/0497 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256136 | HANDA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hitesh HANDA (ATHENS, Georgia); Sama GHALEI (Athens, Georgia) |
| ABSTRACT | Described herein are biocompatible materials that include a nitric oxide (NO) donor embedded in silk fibroin nanoparticles. In one aspect, the nitric oxide donor is present in the hydrophobic core of the silk fibroin nanoparticles such that the nitric oxide donor is encapsulated. The biocompatible materials described herein serve as a biocompatible and inexpensive nitric oxide delivery platform that provide sustained release of nitric oxide. The biocompatible materials are non-toxic and can be used in biomedical applications such as wound healing, where a combination of therapeutic and antibacterial properties of silk and nitric oxide are desired. Additionally, described herein are methods of making the biocompatible materials. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 18/018275 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/008 (20130101) A61L 26/0047 (20130101) A61L 26/0066 (20130101) Original (OR) Class A61L 26/0085 (20130101) A61L 2300/114 (20130101) A61L 2300/406 (20130101) A61L 2300/624 (20130101) A61L 2400/12 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256261 | Dong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pulsethera, Inc. (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pu-Ting Dong (Boston, Massachusetts); Jie Hui (Boston, Massachusetts); Ji-Xin Cheng (Newton, Massachusetts); Yifan Zhu (Allston, Massachusetts) |
| ABSTRACT | Methods of the present invention comprise photoinactivation of catalase in combination with low-concentration peroxide solutions and/or ROS generating agents to provide antibacterial effects. |
| FILED | Thursday, April 20, 2023 |
| APPL NO | 18/303778 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/40 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/208 (20130101) A61L 2101/02 (20200801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Original (OR) Class A61N 5/0616 (20130101) A61N 5/0624 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256360 | Costa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Antonio P. Costa (Tolland, Connecticut); Diane J. Burgess (Storrs, Connecticut) |
| ABSTRACT | A permeate device includes at least one non-porous, gas permeable element configured for contact with a liquid flow and at least one element fabricated from a porous material configured to permit gas flow therethrough. The permeate device may include a vacuum chamber that surrounds an operative portion of a permeation zone. A method for processing a liquid flow to remove entrained gas includes providing a liquid flow that includes an initial level of entrained gas, delivering the liquid flow to a permeate device, wherein the permeate device includes (i) at least one non-porous, gas permeable element configured for direct contact with the flow; and (ii) at least one element fabricated at least in part from a porous material configured so as to permit gas flow therethrough, and applying a negative pressure to the permeate device to draw entrained gas from the flow within an operative portion of the permeate device. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109557 |
| CURRENT CPC | Separation B01D 19/0031 (20130101) Original (OR) Class B01D 19/0063 (20130101) B01D 19/0068 (20130101) B01D 69/107 (20220801) B01D 71/0213 (20220801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257365 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shaomeng Wang (Superior Township, Michigan); Xin Han (Ann Arbor, Michigan); Weiguo Xiang (Ypsilanti, Michigan); Chong Qin (Ann Arbor, Michigan); Tianfeng Xu (Ypsilanti, Michigan); Lijie Zhao (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure provides compounds represented by Formula I: A-L-B1 I, and the salts or solvates thereof, wherein A, L, and B1 are as defined in the specification. Compounds having Formula I are androgen receptor degraders useful for the treatment of cancer and other diseases. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 18/012369 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class C07D 451/06 (20130101) C07D 451/14 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) C07D 487/10 (20130101) C07D 491/08 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257373 | Van Kessel Bochman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julia Catherine Van Kessel Bochman (Bloomington, Indiana); Laura Caroline Brown (Bloomington, Indiana) |
| ABSTRACT | Inhibition of quorum sensing in Gram-negative bacteria, particularly strains of Vibrio, by certain compounds is disclosed. Compositions to treat bacterial infections and methods to treat such infections are also provided. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 18/041241 |
| CURRENT CPC | Heterocyclic Compounds C07D 233/84 (20130101) C07D 333/34 (20130101) C07D 405/06 (20130101) C07D 405/14 (20130101) C07D 409/06 (20130101) C07D 409/12 (20130101) C07D 417/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257418 | Cudic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida Atlantic University Board of Trustees (Boca Raton, Florida); University of Florida Research Foundation (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Predrag Cudic (Boca Raton, Florida); Jay McLaughlin (Gainesville, Florida) |
| ABSTRACT | Novel cyclic peptides, cyclic peptide conjugates and compositions containing them for treating neurological diseases in a subject include an Odorranalectin (OL) sequence or modified OL sequence as a scaffold and a biologically active peptide or protein and/or therapeutic agent conjugated thereto. Methods of treatment of neurological diseases are based on intranasal delivery of a cyclic peptide or cyclic peptide conjugate as described herein. Combinatorial libraries that include a plurality of cyclic peptides have also been developed and can be used to screen for a ligand(s) for a receptor of interest. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/167350 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 31/4045 (20130101) A61K 38/00 (20130101) A61K 47/64 (20170801) A61K 47/65 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/04 (20180101) A61P 25/06 (20180101) A61P 25/16 (20180101) A61P 25/18 (20180101) A61P 25/28 (20180101) A61P 25/36 (20180101) Peptides C07K 5/12 (20130101) Original (OR) Class C07K 7/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257421 | Krusemark et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Casey J. Krusemark (West Lafayette, Indiana); Emily C. Dykhuizen (West Lafayette, Indiana); Sijie Wang (Lafayette, Indiana) |
| ABSTRACT | The present invention relates to series of peptidomimetic compounds selectively targeting CBX8 of polycomb chromobox protein homolog proteins. Pharmaceutical compositions of those compounds and methods of using them in the treatment of diseases involved CBX8 pharmacology, including various cancers and leukemia, by administering therapeutically effective amounts of such compound alone or together with other therapeutics, are within the scope of this disclosure. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/103694 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Peptides C07K 5/1016 (20130101) C07K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257437 | Wong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Altor BioScience LLC (Culver City, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hing C. Wong (Culver City, California); Peter Rhode (Culver City, California); Xiaoyun Zhu (Culver City, California); Kai-Ping Han (Culver City, California) |
| ABSTRACT | The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making the proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/305965 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1774 (20130101) A61K 38/1793 (20130101) A61K 38/2086 (20130101) Peptides C07K 14/5443 (20130101) Original (OR) Class C07K 14/7051 (20130101) C07K 14/7155 (20130101) C07K 16/18 (20130101) C07K 16/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/09 (20130101) C12N 15/62 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257440 | Levin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Noam Levin (Rockville, Maryland); Frank J. Lowery, III (Clarksburg, Maryland); Maria R. Parkhurst (Ellicott City, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed is an isolated or purified T cell receptor (TCR), wherein the TCR has antigenic specificity for a mutated human RAS amino acid sequence with a substitution of glycine at position 12 with valine. The TCRs may recognize G12V RAS presented by an HLA-DR heterodimer. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 18/015781 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257463 | THOMAS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susan Napier THOMAS (Atlanta, Georgia); Jihoon KIM (Atlanta, Georgia) |
| ABSTRACT | Disclosed are hydrogel compositions that can be used to deliver therapeutic agents, including therapeutic proteins, to patients in need thereof. In an embodiment, the therapeutic agent is an immune checkpoint blockade antibody, and the hydrogel is a thermoresponsive polymer crosslinked with a hydrophilic polymer. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 18/015675 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 47/10 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/334 (20130101) C08G 65/33306 (20130101) C08G 2650/58 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2371/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257468 | Bertozzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carolyn R. Bertozzi (Menlo Park, California); Corleone Delaveris (Redwood City, California) |
| ABSTRACT | Provided are cis-binding Siglec agonists. In certain embodiments, the cis-binding Siglec agonists comprise a scaffold bearing Siglec ligands, and a membrane-tethering domain. Also provided are compositions, e.g., pharmaceutical compositions, comprising any of the cis-binding Siglec agonists of the present disclosure. Methods of agonizing Siglec activity, e.g., in an individual in need thereof, are also provided. Kits comprising the cis-binding Siglec agonists, as well as methods of making the cis-binding Siglec agonists, are also provided. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 18/012199 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/7056 (20130101) C07K 16/2851 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257480 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Chris Yang (Stanford, California); Anton Wyss-Coray (Stanford, California) |
| ABSTRACT | Provided herein are methods and compositions for increasing blood-brain barrier permeability in a subject to enhance blood-brain barrier drug transport and methods and composition for identifying agents that regulate blood-brain barrier permeability. |
| FILED | Thursday, December 03, 2020 |
| APPL NO | 17/782501 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/40 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Enzymes C12Y 301/03001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257703 | MALLAPRAGADA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SURYA MALLAPRAGADA (Ames, Iowa); Michael Wannemuehler (Ames, Iowa); Balaji Narasimhan (Ames, Iowa); Sujata Senapati (Ames, Iowa) |
| ABSTRACT | Compositions and methods are provided for rapid and efficient production of antibodies in vitro as well as in vivo, which may be used to neutralize antigens. More specifically, the present invention relates to scaffolds comprised of amphiphilic multiblock copolymers that can form micelles based on nonionic or amphiphilic core blocks as well as ionic blocks, and with an antigen and methods of crosslinking B cell receptors to specifically produce antibodies against the antigen in vitro as well as in vivo in a more efficient method than other available monoclonal antibody production method. |
| FILED | Tuesday, June 08, 2021 |
| APPL NO | 18/001137 |
| CURRENT CPC | Peptides C07K 16/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0635 (20130101) Original (OR) Class C12N 2533/40 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257715 | BREAULT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | David T. BREAULT (Boston, Massachusetts); Daniel R. ZEVE (Boston, Massachusetts) |
| ABSTRACT | The present invention features, in some embodiments, compositions comprising ex vivo or in vitro generated functional enteroendocrine (EE) cells, or enteroids, rectoids, or organoids comprising functional enteroendocrine cells, and methods of obtaining and using such cells for treating metabolic and gastrointestinal diseases, disorders, or conditions. |
| FILED | Wednesday, June 16, 2021 |
| APPL NO | 18/011089 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/38 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0679 (20130101) Original (OR) Class C12N 2501/60 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2506/23 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257716 | Kuo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Calvin Jay Kuo (Palo Alto, California); Shannon Choi (Redwood City, California); Manuel R. Amieva (Stanford, California); Catherine A. Blish (Stanford, California); Maria del Mar Margalef Catala (Redwood City, California); Arjun Rustagi (Redwood City, California) |
| ABSTRACT | Abstract: We describe a robust human adult distal lung organoid method with a procedure for everting organoids to essentially turn them inside out. This then relocates the apical ACE2-expressing surfaces of cells to the organoid exterior, where they can then be easily infected by SARS-CoV-2 added to the tissue culture medium. Further, this method can be used for infection of any distal lung pathogen that infects apically. Alternatively, if a pathogen interacts basolaterally then eversion is not necessary, and the human adult distal lung organoids can be infected as is. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 18/005167 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0689 (20130101) Original (OR) Class C12N 2501/11 (20130101) C12N 2501/15 (20130101) C12N 2501/155 (20130101) C12N 2503/04 (20130101) C12N 2513/00 (20130101) C12N 2533/54 (20130101) C12N 2533/90 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5082 (20130101) G01N 2333/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257723 | Gersbach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles A. Gersbach (Chapel Hill, North Carolina); Adrian Pickar Oliver (Rougemont, North Carolina) |
| ABSTRACT | Disclosed herein arm CRISPR/Cas-based genome editing compositions and methods for treating Duchenne Muscular Dystrophy by restoring dystrophin function. The CRISPR/Cas-based genome editing systems may include a guide RNA (gRNA) targeting a fragment of a mutant dystrophin gene, a Cas protein or a fusion protein comprising the Cas protein, and a donor sequence comprising a fragment of a wild-type dystrophin gene. |
| FILED | Tuesday, April 27, 2021 |
| APPL NO | 17/921316 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2310/20 (20170501) C12N 2320/33 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257726 | Glasgow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chan Zuckerberg Biohub, Inc. (San Francisco, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anum Glasgow (Oakland, California); Jeff Glasgow (Oakland, California); James A. Wells (Oakland, California); Xin Zhou (Oakland, California); Tanja Kortemme (Oakland, California); Irene Lui (Oakland, California) |
| ABSTRACT | This disclosure describes recombinant angiotensin-converting enzyme II (ACE2) polypeptides, fusion proteins, and compositions thereof having improved binding affinity for the SARS-CoV-2 spike protein receptor binding domain relative to wild-type ACE2. Also provided are methods of using the recombinant ACE2 polypeptides, fusion proteins, and compositions thereof for treating subjects infected with a SARS-CoV-2 virus (i.e., subjects with COVID-19), subjects having symptoms suggestive of a SARS-CoV-2 infection, and subjects exposed to or at risk of exposure to SARS-CoV-2 virus. Other virus infections may also be treated. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/997877 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2770/20022 (20130101) Enzymes C12Y 304/17023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257727 | DESAI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Encodia, Inc. (San Diego, California) |
| ASSIGNEE(S) | Encodia, Inc. (San Diego, California) |
| INVENTOR(S) | Kevin DESAI (San Diego, California); Kevin L. GUNDERSON (Encinitas, California); Robert C. JAMES (San Diego, California); Lei SHI (San Diego, California); Stephen VERESPY, III (San Diego, California) |
| ABSTRACT | Provided herein are modified cleavases for removing amino acids from peptides, polypeptides, and proteins. Also provided are methods of using the modified cleavases for treating polypeptides, and kits comprising the modified cleavase. In some embodiments, the methods and the kits also include other components for macromolecule sequencing and/or analysis. |
| FILED | Wednesday, January 18, 2023 |
| APPL NO | 18/098647 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257746 | BAUER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Daniel E. BAUER (Cambridge, Massachusetts); Divya VINJAMUR (Boston, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions related to treating a hemoglobinopathy. Also provided herein a gene therapeutics for the treatment of hemoglobinopathies and the induction of fetal hemoglobin (HbF). |
| FILED | Monday, July 19, 2021 |
| APPL NO | 18/016190 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/166 (20130101) A61K 31/175 (20130101) A61K 31/255 (20130101) A61K 31/352 (20130101) A61K 31/433 (20130101) A61K 31/7088 (20130101) A61K 38/465 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) Peptides C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/16 (20130101) C12N 2310/127 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257755 | Easley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Auburn University (Auburn, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher J. Easley (Auburn, Alabama); Subramaniam Somasundaram (Auburn, Alabama) |
| ABSTRACT | Described herein are DNA-nanostructures that can be used in an assay to detect and/or quantify an analyte of interest. Aspects of the DNA-nanostructure can include a single DNA molecule composed of hairpin structural motifs, an anchor recognition moiety, and a signal moiety, where the anchor recognition moiety and the signal moiety are in effective proximity to each other such that the tethered diffusion of the signal molecule can be altered based upon binding status of the anchor recognition moiety. Also described herein are methods of making and using the DNA-nanostructures. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/158466 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/122 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 2565/518 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257756 | Henderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Mark J. Henderson (Damascus, Maryland); Michael H. Ronzetti (Silver Spring, Maryland); Bolormaa Baljinnyam (Rockville, Maryland); Tino W. Sanchez (Rockville, Maryland); Samuel G. Michael (Germantown, Maryland); Ashley E. Owens (Murfreesboro, Tennessee); Anton Simeonov (Bethesda, Maryland) |
| ABSTRACT | The disclosure provides methods for carrying out Real Time Cellular Thermal Shift Assays (RT-CETSA). Also provided are molecular constructs and protein constructs for use in such assays and devices suitable for carrying out such assays. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 18/020843 |
| CURRENT CPC | Peptides C07K 14/70521 (20130101) C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/003 (20130101) C12N 15/86 (20130101) C12N 15/625 (20130101) Original (OR) Class C12N 2330/51 (20130101) Enzymes C12Y 101/01027 (20130101) C12Y 105/01003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257781 | Church et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Kevin M. Esvelt (Auburndale, Massachusetts); Prashant G. Mali (La Jolla, California) |
| ABSTRACT | Methods of modulating expression of a target nucleic acid in a cell are provided including use of multiple orthogonal Cas9 proteins to simultaneously and independently regulate corresponding genes or simultaneously and independently edit corresponding genes. |
| FILED | Thursday, April 06, 2023 |
| APPL NO | 18/296446 |
| CURRENT CPC | Peptides C07K 2/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/85 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/3519 (20130101) C12N 2320/33 (20130101) C12N 2320/50 (20130101) C12N 2800/40 (20130101) C12N 2800/80 (20130101) C12N 2800/107 (20130101) C12N 2810/10 (20130101) C12N 2830/00 (20130101) C12N 2830/34 (20130101) C12N 2999/007 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257791 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Lynch (Durham, North Carolina); John Decker (Durham, North Carolina) |
| ABSTRACT | Methods and kits are provided for producing Griffithsin. The methods include providing a genetically modified microorganism comprising a gene encoding Griffithsin protein operably linked to an inducible promotor and growing the genetically modified microorganism under conditions that induce the promotor and cause expression of griffithisin. The Griffithsin is purified by releasing Griffithsin from the microorganism by cellular disruption, performing a precipitation step to remove contaminating protein and nucleic acids, and performing an anion exchange chromatography step. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/906501 |
| CURRENT CPC | Peptides C07K 14/405 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/635 (20130101) C12N 2800/101 (20130101) C12N 2830/002 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257817 | SMOYER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Conlumbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | WILLIAM E. SMOYER (Bexley, Ohio); Sagar Bhayana (Conlumbus, Ohio); Shipra Agrawal (Upper Arlington, Ohio) |
| ABSTRACT | Methods of identifying one or more genomic regions associated with kidney disease and/or its treatment are described. The methods include administering a glucocorticoid to a first group of subjects; administering a thiazolidinedione to a second group of subjects; and identifying a plurality of genomic regions affected in the first group and the second group, wherein the subjects have a kidney disease or are animal models of a kidney disease. Methods of identifying a drug for treatment of nephrotic syndrome are also described. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 18/016153 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257822 | DE VLAMINCK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Iwijn DE VLAMINCK (Ithaca, New York); Alexandre Pellan CHENG (Ithaca, New York); Matthew Pellan CHENG (Ithaca, New York); Francisco Miguel MARTY (Ithaca, New York); Jerome RITZ (Ithaca, New York) |
| ABSTRACT | The present disclosure is directed to novel methods for detecting tissue damage, graft-versus-host disease (GVHD), microbial infections, presence of a tumor, and loss of engraftment in a subject using cell-free DNA (cfDNA) profiling. The methods of the disclosure are in part based on the recognition that damaged tissues, microbes during an infection, tumors, and donor cells (e.g., in a hematopoietic cell transplantation) shed small fragments of cfDNA into blood circulation. |
| FILED | Friday, April 23, 2021 |
| APPL NO | 17/920931 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 1/6888 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257825 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter P. Lee (San Marino, California); Colt Egelston (Duarte, California); Weihua Guo (Duarte, California); Jiayi Tan (Duarte, California) |
| ABSTRACT | The disclosure provides, inter alia, breast cancer biomarkers, methods of detecting exhausted CD8+ T cells in breast cancer patients, methods of detecting CD26+CD4+ T cells in breast cancer patients, methods of treating breast cancer patients, and methods of identifying risk outcomes for breast cancer patients. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/106248 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) G01N 33/57415 (20130101) G01N 2333/70514 (20130101) G01N 2333/70517 (20130101) G01N 2333/70592 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258476 | Rezvanitabar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ahmad Rezvanitabar (Atlanta, Georgia); Evren Fatih Arkan (Atlanta, Georgia); Fahrettin Levent Degertekin (Atlanta, Georgia) |
| ABSTRACT | Systems and methods are disclosed for improving broad bandwidth performance of CMUT elements and arrays using negative capacitance-based impedance matching. The disclosed systems and methods provide a controllable compromise balance between electrical power transfer, acoustic reflectivity, and signal-to-noise ratio. Certain implementations utilize active control of impedance network parameters based on a DC bias input to the CMUT. Instead of minimizing electrical reflection, acoustic reflectivity is controlled to provide improved SNR-bandwidth. Negative capacitance-based matching is tunable to accommodate collapsed mode CMUTs where capacitance and frequency response changes significantly with DC bias. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 18/005435 |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0215 (20130101) B06B 1/0292 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/24 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/0073 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258630 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuebing Zheng (Austin, Texas); Youngsun Kim (Austin, Texas) |
| ABSTRACT | Disclosed herein are devices, systems, and methods for analyte sensing with optothermally generated bubbles in biphasic liquid samples. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 18/015808 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 33/56983 (20130101) G01N 2201/06 (20130101) G01N 2333/11 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258633 | RODWELL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Timothy RODWELL (La Jolla, California); Antonino CATANZARO (La Jolla, California); Marva SEIFERT (La Jolla, California); Joseph WANG (La Jolla, California); Eva Vargas ORGAZ (La Jolla, California); Victor Ruiz Valdepenas MONTIEL (La Jolla, California) |
| ABSTRACT | In one aspect, the disclosure relates to test strips for detecting and/or monitoring the treatment of a disease in a subject. The test strips are inexpensive and disposable and can be used directly with clinical biological samples from patients including, but not limited to, blood, plasma, saliva, and urine. Also disclosed are methods of using the test strips to quantify antigens produced by a virus or microorganism causing an infectious disease. The methods can be conducted at a point of care for a patient and do not require expensive equipment or extensive operator training. The methods are also rapid to complete and can be used to monitor progress in the treatment of a disease This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 18/014220 |
| CURRENT CPC | Peptides C07K 16/10 (20130101) C07K 16/1289 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) G01N 33/553 (20130101) G01N 33/569 (20130101) Original (OR) Class G01N 2333/35 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258635 | Lowery, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Frank J. Lowery, III (Clarksburg, Maryland); Sri Krishna (Bethesda, Maryland); Paul F. Robbins (Chevy Chase, Maryland); Steven A. Rosenberg (Potomac, Maryland); Gregoire Y. Altan-Bonnet (Bethesda, Maryland) |
| ABSTRACT | Disclosed are methods of obtaining a cell population enriched for T cells with a phenotype, the method comprising: (a) obtaining a bulk population of T cells from a tumor sample of a patient; (b) specifically selecting T cells with a phenotype comprising markers CD3+, CD39−, and CD69− from the bulk population; and (c) separating the cells selected in (b) from cells which lack the phenotype to obtain a cell population enriched for T cells with the phenotype. Related methods of treating or preventing cancer, methods of selecting a therapy for a cancer patient, and methods for predicting the clinical response to immunotherapy in a cancer patient are also disclosed. Isolated or purified cell population obtained according to the methods and related pharmaceutical compositions are also disclosed. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 18/024430 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) Original (OR) Class G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258641 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Upstate Affiliate Organization d/b/a Greenville Health System (Greenville, South Carolina); Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven L. Young (Durham, North Carolina); Bruce Arthur Lessey (Greenville, South Carolina); Jae Wook Jeong (Grand Rapids, Michigan) |
| ABSTRACT | The present invention provides a method of diagnosing endometriosis and/or infertility in a subject, comprising: a) obtaining a sample from the subject; b) detecting a level of expression of a SIRT1 gene and/or protein in the sample; c) detecting a level of expression of a BCL6 gene and/or protein in the sample; d) comparing the level of expression detected in (b) with the level of expression of a SIRT1 gene and/or protein in a sample obtained from a control subject or a population of control subjects; e) comparing the level of expression detected in (c) with the level of expression of a BCL6 gene and/or protein in a sample obtained from a control subject or a population of control subjects; and f) diagnosing the subject as having infertility when the subject has a level of expression of the SIRT1 gene and/or protein greater than the level of expression of the SIRT1 gene and/or protein of the control subject or population of control subjects and also has a level of expression of the BCL6 gene and/or protein that is greater than the level of expression of the BCL6 gene and/or protein of the control subject or population of control subjects. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/929510 |
| CURRENT CPC | Peptides C07K 16/40 (20130101) C07K 2317/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/689 (20130101) G01N 33/6872 (20130101) G01N 33/57449 (20130101) Original (OR) Class G01N 2333/98 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258788 | Vienneau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emelina Prevost Vienneau (Walnut Cove, North Carolina); Brett C. Byram (Brentwood, Tennessee) |
| ABSTRACT | One aspect of the invention relates to method and system for increasing signal-to-noise ratio (SNR) and suppressing range lobe artifacts in ultrasound imaging or sensing, active sonar, LIDAR, and/or radar. The method includes forming a coded excitation waveform with a chip waveform and a binary sequence; transmitting the coded excitation waveform into a medium of interest, and receiving signals generated from the medium of interest responsive to excitation of the coded excitation waveform; and performing pulse compression on the received signals using a decoding filter to increase the SNR and suppress the range lobe artifacts. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 18/024315 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52026 (20130101) Original (OR) Class G01S 7/52047 (20130101) G01S 15/104 (20130101) G01S 15/8961 (20130101) G01S 15/8979 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260087 | SRIVASTAVA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Madhur SRIVASTAVA (Ithaca, New York); Jack H. FREED (Ithaca, New York) |
| ABSTRACT | Methods, systems and programs for denoising a signal using an undecimated discrete wavelet transformation are provided. The methods use signal location windows. The signal location windows may be used before or after thresholding. When signal location windows are used after thresholding coefficients within the signal location windows may be restored to their original values. When signal location windows are used before thresholding, coefficients within the signal location windows may be unchanged by the thresholding. The signal location windows may be used only on a subset of decomposition levels that are thresholded. The signal location windows may be used on both the Detail components and the highest decomposition level for thresholding of the Approximation component. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 18/012426 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/148 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) Original (OR) Class G06T 2207/20016 (20130101) G06T 2207/20064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260256 | Chennubhotla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| INVENTOR(S) | Srinivas C. Chennubhotla (Pittsburgh, Pennsylvania); Akif Burak Tosun (Pittsburgh, Pennsylvania); Jeffrey Fine (Pittsburgh, Pennsylvania) |
| ABSTRACT | A computational pathology method includes receiving multi-parameter cellular and/or sub-cellular imaging data for an image of a tissue sample, and locating and segmenting a plurality of tissue components of the tissue sample in the multi- parameter cellular and sub-cellular imaging data to generate segmented multi¬ parameter cellular and sub-cellular imaging data. The method further includes applying a parametric feature modelling scheme to certain of the tissue components in the segmented multi-parameter cellular and sub-cellular imaging data, wherein the parametric feature modelling scheme is generated from a dictionary of pre-existing diagnostically relevant histological patterns and comprises a number of structural features adapted for defining a number of disease entities of a disease, and wherein the applying includes determining a quantification of each of the structural features for the tissue sample, and classifying a state of the disease in the tissue sample based the determined quantification of each of the structural features. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 18/014514 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/74 (20170101) G06T 2207/30024 (20130101) G06T 2207/30096 (20130101) Image or Video Recognition or Understanding G06V 10/26 (20220101) G06V 10/255 (20220101) G06V 10/7715 (20220101) Original (OR) Class G06V 20/695 (20220101) G06V 20/698 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230255295 | Lebel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Galvion Ltd. (Portsmouth, New Hampshire) |
| ASSIGNEE(S) | Galvion Ltd. (Portsmouth, New Hampshire) |
| INVENTOR(S) | Stéphane Lebel (St. Redempteur, Canada); Dominic Giroux Bernier (St. Gabriel De Brandon, Canada); Michael James McGinn (Montreal, Canada) |
| ABSTRACT | Systems and methods for selectively attaching an accessory mount to a helmet are disclosed. A carrier may be used to position the accessory mount on the helmet. The accessory mount may be positioned on the helmet without engaging the rim of the helmet. The carrier may be compatible with various accessory mounts to permit mounting of different accessories. The accessory mount may be a powered mount for attachment to a Night Vision Device (NVD) such as Enhanced Night Vision Goggles (ENVG), or the accessory mount may be a non-powered accessory mount. |
| FILED | Wednesday, November 09, 2022 |
| APPL NO | 17/984008 |
| CURRENT CPC | Hats; Head Coverings A42B 3/04 (20130101) A42B 3/042 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255552 | Inan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Omer Inan (Atlanta, Georgia); Samer Mabrouck (Atlanta, Georgia) |
| ABSTRACT | An exemplary embodiment of the present disclosure provides a system for assessing joint health comprising a joint sensor configured to measure at least one non-acoustic characteristic of a joint during movement; a bioimpedance sensor configured to measure bioimpedance of a joint structure exposed to electrical current at a plurality of frequencies; a processor; and a memory, the memory comprising instructions that, when executed by the processor, cause the processor to provide an assessment of joint health through interpretation of measurements from the joint sensor and the bioimpedance sensor. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 18/012451 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0002 (20130101) A61B 5/0537 (20130101) A61B 5/1114 (20130101) A61B 5/1121 (20130101) A61B 5/1126 (20130101) A61B 5/4595 (20130101) Original (OR) Class A61B 5/4878 (20130101) A61B 5/6829 (20130101) A61B 2562/06 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255880 | DINOVO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Guild Associates Inc. (Dublin, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew DINOVO (Columbus, Ohio); Matthew SMIECHOWSKI (Westerville, Ohio); Francis VERHOFF (Cincinnati, Ohio); Dominic DINOVO (Delaware, Ohio) |
| ABSTRACT | The current disclosure provides compositions and methods for treating and/or debriding damaged or dying tissue resulting from a range of injuries and conditions without requiring surgical personnel or facilities. The compositions can be utilized in the field close to where the injury occurred. The compositions include a covalently bonded and immobilized protease enzyme included in a medium that can have a variety of forms and further include a range of additives to further effect the safe and effective removal of dead or damaged tissue. The compositions can be transported and utilized in the field without refrigeration and without any special handling. |
| FILED | Thursday, February 16, 2023 |
| APPL NO | 18/170282 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) A61P 29/00 (20180101) A61P 31/02 (20180101) A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255951 | DALVI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (AUSTIN, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maithili P. DALVI (Dallas, Texas); Elisabeth D. MARTINEZ (Dallas, Texas); John D. MINNA (Dallas, Texas); Juan BAYO-FINA (Dallas, Texas); Amit DAS (Dallas, Texas) |
| ABSTRACT | Disclosed are methods for the use of Jumonji C demethylase inhibitors for the radiosensitization of cancers cells and the treatment and prevention of chemotherapy resistance in cancer. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055045 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/44 (20130101) A61K 31/55 (20130101) A61K 31/282 (20130101) A61K 31/337 (20130101) A61K 31/444 (20130101) Original (OR) Class A61K 33/243 (20190101) A61K 45/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230256442 — SYSTEMS AND METHODS FOR TRAPPING AND TRANSPORTING SMALL PARTICLES WITH ACOUSTIC FORCES
| US 20230256442 | Cummer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven Cummer (Durham, North Carolina); Junfei Li (Durham, North Carolina); Chen Shen (Durham, North Carolina) |
| ABSTRACT | The present disclosure describes systems and methods for versatile acoustic tweezer trapping and transport configurations. Examples can use ultrasound for contact-free, biocompatible, and precise manipulation of particles from millimeter to sub-micrometer scale along a narrow and complex path. Examples include spatially complex particle trapping and manipulation inside a boundary-free chamber using a single pair of sources and a shadow waveguide. The shadow waveguide structure can be disposed just outside a microfluidic chamber to guide and control the acoustic wave fields inside the chamber. The shadow waveguide can create a tightly confined, spatially complex acoustic field inside the chamber without an interior structure that could interfere with net flow or transport. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/111176 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2300/14 (20130101) B01L 2300/168 (20130101) B01L 2400/049 (20130101) B01L 2400/0439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256451 | Selden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ANDE Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard F. Selden (Lincoln, Massachusetts); Eugene Tan (Lexington, Massachusetts) |
| ABSTRACT | A biochip for the integration of all steps in a complex process from the insertion of a sample to the generation of a result, performed without operator intervention includes microfluidic and macrofluidic features that are acted on by instrument subsystems in a series of scripted processing steps. Methods for fabricating these complex biochips of high feature density by injection molding are also provided. |
| FILED | Tuesday, February 21, 2023 |
| APPL NO | 18/172189 |
| CURRENT CPC | Separation B01D 69/02 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502723 (20130101) B01L 3/502738 (20130101) B01L 3/502753 (20130101) B01L 7/52 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2200/12 (20130101) B01L 2200/16 (20130101) B01L 2200/142 (20130101) B01L 2300/087 (20130101) B01L 2300/123 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) B01L 2300/0874 (20130101) B01L 2300/1822 (20130101) B01L 2400/0421 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) B01L 2400/0655 (20130101) B01L 2400/0677 (20130101) B01L 2400/0688 (20130101) Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 11/08 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0025 (20130101) B29C 2045/0027 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/26 (20130101) G01N 27/44704 (20130101) G01N 27/44721 (20130101) G01N 27/44743 (20130101) G01N 27/44791 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4998 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256678 | Kutchko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Cynthia Kutchko (Pittsburgh, Pennsylvania); Bryan William Wilkinson (Pittsburgh, Pennsylvania); Michael Anthony Bubas (Pittsburgh, Pennsylvania) |
| ABSTRACT | A computer system for part production using flow infill design receives a computer-aided design file that describes physical dimensions of a target object (120). The computer system identifies a physical boundary portion (300) of the target object within the CAD file. The computer system generates a first tool path to additively manufacture the physical boundary portion (300). Additionally, the computer system sends instructions to a computer system in communication with a dispenser (130) that cause the dispenser to implement the first tool path while dispensing a boundary material. Further, the computer system generates a command to dispense the coreactive infill material (310) within the physical boundary portion. |
| FILED | Monday, May 03, 2021 |
| APPL NO | 18/003934 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/209 (20170801) B29C 64/393 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257103 | Zook et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Trevor A. Zook (Stratford, Connecticut); Jason Quevedo (Stratford, Connecticut); Ken Chu (Stratford, Connecticut); David Tam (Seymour, Connecticut) |
| ABSTRACT | An aircraft includes a main body having an empennage, a main rotor assembly mounted on the main body, and a movable control surface assembly supported on the empennage. The movable control surface assembly includes a tube extending from the empennage along a tube axis to a free end, the tube being supported for rotation about the tube axis with respect to the empennage, and a movable control surface mounted on the tube for rotation therewith. The movable control surface is supported on the tube by a connection element that couples the movable control surface to the free end of the tube to rotatably fix the movable control surface with respect to the tube. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/672376 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 9/02 (20130101) Original (OR) Class B64C 29/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257308 | Goswami et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Ramasis Goswami (Alexandria, Virginia); Syed B. Qadri (Fairfax Station, Virginia) |
| ABSTRACT | A method of making an Al—B4C composite with Mg addition comprising providing a first mixture of B4C, Al and Mg powder, producing a powder mixture, adding Mg to the powder mixture, forming pellets, creating a composite, annealing the composite, and forming an Al—Mg—B4C composite. An Al—B4C composite with Mg addition comprising Al, Mg comprising 4 wt. %, and B4C comprising 8 wt. %. An Al—B4C composite with Mg addition made from the steps comprising providing a first mixture of B4C, Al and Mg powder, producing a powder mixture, adding Mg to the powder mixture, forming pellets, creating a composite, annealing the composite, and forming an Al—Mg—B4C composite. |
| FILED | Wednesday, February 08, 2023 |
| APPL NO | 18/107224 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/563 (20130101) Original (OR) Class C04B 35/62615 (20130101) C04B 35/62695 (20130101) C04B 41/0081 (20130101) C04B 2235/61 (20130101) C04B 2235/401 (20130101) C04B 2235/402 (20130101) C04B 2235/3821 (20130101) C04B 2235/5445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257353 | Miao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Lei Miao (San Jose, California); Linxian Li (Malden, Massachusetts); Daniel Griffith Anderson (Framingham, Massachusetts); Yuxuan Huang (Cambridge, United Kingdom) |
| ABSTRACT | Provided herein are lipidoid compounds of Formulae (I) and (II), and pharmaceutically acceptable salts, co-crystals, tautomers, stereoisomers, solvates, hydrates, polymorphs, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive lipidoid compounds, compositions, or formulations for treating and/or preventing diseases (e.g., genetic disease, proliferative disease, hematological disease, neurological disease, painful condition, psychiatric disorder, metabolic disorder, long-term medical condition, inflammatory disease, autoinflammatory disease, liver disease, lung disease, spleen disease, familial amyloid neuropathy, cardiovascular disease, viral infection, infectious disease, fibrotic condition, or autoimmune disease) in a subject, methods for synthesizing the compounds described herein, and compounds described herein synthesized by the synthetic methods described herein. The compounds are effective carriers for the delivery of an agent such as a polynucleotide (e.g., RNA) to a cell. |
| FILED | Thursday, July 28, 2022 |
| APPL NO | 17/875982 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 2039/53 (20130101) Acyclic or Carbocyclic Compounds C07C 237/06 (20130101) C07C 251/08 (20130101) Heterocyclic Compounds C07D 233/40 (20130101) Original (OR) Class C07D 403/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257440 | Levin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Noam Levin (Rockville, Maryland); Frank J. Lowery, III (Clarksburg, Maryland); Maria R. Parkhurst (Ellicott City, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed is an isolated or purified T cell receptor (TCR), wherein the TCR has antigenic specificity for a mutated human RAS amino acid sequence with a substitution of glycine at position 12 with valine. The TCRs may recognize G12V RAS presented by an HLA-DR heterodimer. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 18/015781 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257463 | THOMAS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susan Napier THOMAS (Atlanta, Georgia); Jihoon KIM (Atlanta, Georgia) |
| ABSTRACT | Disclosed are hydrogel compositions that can be used to deliver therapeutic agents, including therapeutic proteins, to patients in need thereof. In an embodiment, the therapeutic agent is an immune checkpoint blockade antibody, and the hydrogel is a thermoresponsive polymer crosslinked with a hydrophilic polymer. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 18/015675 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 47/10 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/334 (20130101) C08G 65/33306 (20130101) C08G 2650/58 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2371/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257598 | BOWMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG INDUSTRIES OHIO, INC. (CLEVELAND, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MARK PAUL BOWMAN (NEW KENSINGTON, Pennsylvania); VENICE POMTILA AKELO MAGUNGA (NEWARK, Delaware); LUCAS MANUEL DOS SANTOS FREIRE (PITTSBURGH, Pennsylvania) |
| ABSTRACT | A rubber coating layer is prepared from a sprayable aqueous coating dispersion including: a rubber dispersion including a rubber binder dispersed in an aqueous medium, a sulfur-containing vulcanization agent, and a platy inorganic material. The coating dispersion or a film formed from the coating dispersion is vulcanized at a temperature of from 100° C. to less than 160° C. for up to 1 hour to form the rubber coating layer having a melt temperature of greater than 60° C. A sprayable pre-vulcanized coating dispersion is prepared from a coating dispersion including: a rubber dispersion comprising a rubber binder dispersed in an aqueous medium, a sulfur-containing vulcanization agent, and a platy inorganic material. The coating dispersion is vulcanized at a temperature of from 70° C. to less than the boiling point of the aqueous medium to form the pre-vulcanized coating dispersion. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055062 |
| CURRENT CPC | Treatment or Chemical Modification of Rubbers C08C 19/14 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/48 (20180101) Original (OR) Class C09D 7/61 (20180101) C09D 7/65 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257732 | van Zee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Mark van Zee (Los Angeles, California); Dino Di Carlo (Los Angeles, California); Joseph de Rutte (Los Angeles, California); Sohyung Lee (Pasadena, California); Robert Damoiseaux (Los Angeles, California); Cayden Williamson (Los Angeles, California) |
| ABSTRACT | Degradable hollow shell particles are disclosed that can encapsulate cells within the hollow inner cavity that allows for the high-throughput screening and sorting of the encapsulated cells based on their phenotypic properties. The solid-phase of the particle is porous such that solution exchange can occur between the external environment and the interior cavity. Further, the solid-phase contains degradable crosslinkers and can be degraded to release enclosed biological entities. An example embodiment consists of encapsulating a cell within the hollow shell particle, allowing the cell to accumulate biomass, selecting hollow shell particles based on accumulated biomass, and degrading the hollow shell particles to release the cells and develop hyper-producing cell lines. Exemplary cell types include microalgae, mammalian cells, bacteria, yeast, and fungi. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 18/006382 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 5/00 (20130101) C12N 5/0012 (20130101) C12N 11/04 (20130101) Original (OR) Class C12N 11/10 (20130101) C12N 2509/00 (20130101) C12N 2533/50 (20130101) C12N 2533/70 (20130101) C12N 2537/10 (20130101) C12N 2539/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257780 | UNWALLA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HOSHANG JEHANGIR UNWALLA (MIAMI, Florida); SRINIVASAN CHINNAPAIYAN (MIAMI, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (MIAMI, Florida) |
| INVENTOR(S) | HOSHANG JEHANGIR UNWALLA (MIAMI, Florida); SRINIVASAN CHINNAPAIYAN (MIAMI, Florida) |
| ABSTRACT | The invention pertains to an inducible CRISPR system for controlling expression of a CRISPR complex with an inducible fusion promoter. One embodiment of the invention provides HIV LTR-minimal Drosophila hsp70 fusion promoter that can be used for inducible co-expression of gRNA and Cas9 in HIV-infected cells to target cellular cofactors such as Cyclin T1. A single introduction of such embodiment leads to sustained suppression of HIV replication in stringent, chronically infected HeLa-CD4 cell lines as well as in T-cell lines. In another embodiment, the invention further relates to enhancement of HIV suppression by incorporating cis-acting ribozymes immediately upstream of the gRNA in the inducible CRISPR system construct. The inducible fusion promoter is adaptable for other tissue- or cell-type specific expression of the inducible CRISPR system. |
| FILED | Wednesday, March 29, 2023 |
| APPL NO | 18/192191 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/85 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2740/16041 (20130101) C12N 2830/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257791 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Lynch (Durham, North Carolina); John Decker (Durham, North Carolina) |
| ABSTRACT | Methods and kits are provided for producing Griffithsin. The methods include providing a genetically modified microorganism comprising a gene encoding Griffithsin protein operably linked to an inducible promotor and growing the genetically modified microorganism under conditions that induce the promotor and cause expression of griffithisin. The Griffithsin is purified by releasing Griffithsin from the microorganism by cellular disruption, performing a precipitation step to remove contaminating protein and nucleic acids, and performing an anion exchange chromatography step. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/906501 |
| CURRENT CPC | Peptides C07K 14/405 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/635 (20130101) C12N 2800/101 (20130101) C12N 2830/002 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257907 | REN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Zhifeng REN (Pearland, Texas); Jiming BAO (Pearland, Texas); Shuai YUE (Pearland, Texas); Fei TIAN (Richmond, Texas); Geethal Amila Udalamatta GAMAGE (Fremont, California); Gang CHEN (Carlisle, Massachusetts); Jungwoo SHIN (Cambridge, Massachusetts) |
| ABSTRACT | Herein provided are cubic boron arsenide (c-BAs) single crystals having an unexpectedly high ambipolar mobility at room temperature, µa, at one or more locations thereof that is greater than or equal to 1500, 1600, 1700, 1800, 1900, 2000, 2100, 2200, 2300, 2400, 2500, 2600, 3000, 4000, 5000, 6000, 7000, 8000, 9000, or 10000 cm2V-1s-1, wherein the ambipolar mobility is defined as: µa = 2µeµh/(µe + µh), wherein µe is electron mobility and µh is hole mobility, and having a room temperature thermal conductivity at the one or more locations thereof that is greater than or equal to 1000 Wm-1K-1. Methods of making and using the c-BAs single crystals are also provided. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/100291 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/04 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/76 (20130101) C01P 2002/82 (20130101) C01P 2002/84 (20130101) C01P 2004/02 (20130101) C01P 2004/03 (20130101) C01P 2006/32 (20130101) C01P 2006/40 (20130101) C01P 2006/80 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/16 (20130101) C30B 25/18 (20130101) C30B 29/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258203 | Keplinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Christoph Matthias Keplinger (Gerlingen, Germany); Xingrui Wang (Boulder, Colorado); Shane Karl Mitchell (Boulder, Colorado) |
| ABSTRACT | High strain hydraulically amplified self-healing electrostatic transducers having increased maximum theoretical and practical strains are disclosed. In particular, the actuators include electrode configurations having a zipping front created by the attraction of the electrodes that is configured orthogonally to a strain axis along which the actuators. This configuration produces increased strains. In turn, various form factors for the actuator configuration are presented including an artificial circular muscle and a strain amplifying pulley system. Other actuator configurations are contemplated that include independent and opposed electrode pairs to create cyclic activation, hybrid electrode configurations, and use of strain limiting layers for controlled deflection of the actuator. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/138621 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1075 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 5/006 (20130101) Original (OR) Class F15B 15/103 (20130101) F15B 21/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258427 | Doolittle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cubic Corporation (San Diego, California) |
| ASSIGNEE(S) | Cubic Corporation (San Diego, California) |
| INVENTOR(S) | Keith William Doolittle (Orlando, Florida); Lifan Hua (Orlando, Florida); David Robert Simmons (Orlando, Florida); Adam Robb Syme (Orlando, Florida); Robyn Ann Yost (Orlando, Florida); Peter Jonathan Martin (Orlando, Florida); Carson Alan Brown (Orlando, Florida); Michele Fleming (Orlando, Florida); Vern Edgar Campbell (Orlando, Florida) |
| ABSTRACT | The present disclosure explains a system and method for determining a spatial orientation of a weapon in an augmented reality training environment. Fiducial markers are mounted on the weapon and two cameras are mounted on a user's head to capture spatial coordinates of the plurality of fiducial markers. The spatial coordinates of fiducial markers are processed to determine the spatial orientation of the weapon and a simulated discharging of the weapon. Augmented reality imagery is generated based on the spatial orientation and the detected movement. The augmented reality imagery corresponding to the spatial orientation and discharging of the weapon is rendered for the user with the head-mounted display. |
| FILED | Thursday, November 03, 2022 |
| APPL NO | 17/980461 |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 33/00 (20130101) Original (OR) Class Electric Digital Data Processing G06F 3/012 (20130101) Image Data Processing or Generation, in General G06T 7/74 (20170101) G06T 19/006 (20130101) G06T 2207/30204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258495 | Sanyal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Subrata Sanyal (Eastvale, California); Joseph A. Fiordilino (Corona, California) |
| ABSTRACT | Exemplary embodiments include at least one modular container that can be assembled to emulate a desired atmosphere. Each container includes apertures on opposing ends of the container to allow EMR to enter and exit the container. Each container can include temperature control systems, humidity control systems, fan arrays to emulate wind/turbulence, and a plurality of sensors to measure the current conditions within the container, all of which can be installed within the container's walls. |
| FILED | Wednesday, April 19, 2023 |
| APPL NO | 18/136454 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/0252 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258864 | PYUN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dong-Chul "Jeffrey" PYUN (Tucson, Arizona); Robert A. NORWOOD (Tucson, Arizona); Julie Ilana FRISH (Tucson, Arizona); Tristan Stephen KLEINE (Tucson, Arizona) |
| ABSTRACT | The present invention is directed to refractive index contrast (“RIC”) polymers and methods for producing and using the same. In one particular embodiment, RIC polymers of the invention can be used as waveguides. RIC polymers of the invention are produced from a monomeric mixture comprising a first monomer and a second monomer comprising an acid-labile protecting group, where a first polymer produced from the first monomer has a different refractive index compared to the refractive index of a second polymer produced from the second monomer. The base refractive index of RIC polymers can be tuned by controlling the amount of the first and the second monomers. Furthermore, the refractive index of the waveguide can be modulated by the amount of acid-labile protecting group removal. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 18/043630 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/138 (20130101) G02B 6/1221 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/027 (20130101) G03F 7/0046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230259635 | Bao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona); University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tiffany Bao (Tempe, Arizona); Connor Nelson (Tempe, Arizona); Zhuoer Lyu (Phoenix, Arizona); Tudor Dumitras (College Park, Maryland); Octavian Suciu (College Park, Maryland) |
| ABSTRACT | A computer-implemented system incorporates a time-varying view of exploitability in the form of Expected Exploitability (EE) to learn and continuously estimate the likelihood of functional software exploits being developed over time. The system characterizes the noise-generating process systematically affecting exploit prediction, and applies a domain-specific technique (e.g., Feature Forward Correction) to learn EE in the presence of label noise. The system also incorporates timeliness and predictive utility of various artifacts, including new and complementary features from proof-of-concepts, and includes scalable feature extractors. The system is validated on three case studies to investigate the practical utility of EE, showing that the system incorporating EE can qualitatively improve prioritization strategies based on exploitability. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169674 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/577 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230259806 | BRINGEWATT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); Government of the United States of America as Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob BRINGEWATT (Hyattsville, Maryland); Przemyslaw BIENIAS (San Francisco, California); Timothy QIAN (Rockville, Maryland); Igor BOETTCHER (Washington, District of Columbia); Alexey GORSHKOV (Potomac, Maryland) |
| ABSTRACT | A system for the measurement of field properties includes a quantum system, a processor, and a memory. The quantum system includes a plurality of quantum sensors coupled to a field. Each sensor of the plurality of quantum sensors is located at a position in the field. The position depends on parameters. Each sensor of the plurality of quantum sensors is entangled. The memory includes instructions stored thereon, which, when executed by the processor, cause the quantum system to: access a signal of the quantum system; sense a plurality of interdependent a local field amplitudes corresponding to the plurality of quantum sensors by locally probing the field by each sensor of the plurality of quantum sensors; estimate a function of the parameters at a position x0, where x0 is a position without a quantum sensor of the plurality of quantum sensors; and estimate an amplitude of the field at the position x0 based on the estimated function of the parameters. |
| FILED | Tuesday, November 01, 2022 |
| APPL NO | 17/978420 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) G06N 10/70 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260224 | Greunke |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Larry Clay Greunke (Seaside, California) |
| ABSTRACT | This disclosure and exemplary embodiments described herein provide a Parallel Content Authoring Method and Tool for Procedural Guidance, and a Remote Expert Method and System Utilizing Quantitative Quality Assurance in Mixed Reality. The implementation described herein is related to the generation of content/instruction set that can be viewed in different modalities, including but not limited to mixed reality, VR, audio text, however it is to be understood that the scope of this disclosure is not limited to such application. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/111440 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/24573 (20190101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260415 | Greunke |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Larry Clay Greunke (Seaside, California) |
| ABSTRACT | This disclosure and exemplary embodiments described herein provide a Parallel Content Authoring Method and Tool for Procedural Guidance, and a Remote Expert Method and System Utilizing Quantitative Quality Assurance in Mixed Reality. The implementation described herein is related to the generation of content/instruction set that can be viewed in different modalities, including but not limited to mixed reality, VR, audio text, however it is to be understood that the scope of this disclosure is not limited to such application. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/111458 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 13/20 (20130101) G06T 17/20 (20130101) G06T 2200/24 (20130101) G06T 2210/52 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/02 (20130101) Original (OR) Class G09B 19/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260680 | Hammig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Hammig (Dexter, Michigan); Nicholas Kotov (Ann Arbor, Michigan); Jing Lyu (Beijing, China PRC); Suneel Joglekar (West Lafayette, Indiana) |
| ABSTRACT | A method of fabricating a conductor includes preparing an aramid nanofiber solution in which a matrix of aramid nanofibers is dispersed, preparing a dispersion of copper nanoparticles, each copper nanoparticle of the dispersion of cooper nanoparticles having an organic capping ligand attached to the copper nanoparticle, and incorporating copper nanoparticles of the dispersion of copper nanoparticles into the matrix of aramid nanofibers such that each incorporated copper nanoparticle is bonded to a respective aramid nanofiber of the matrix of aramid nanofibers via the organic capping ligand to which the copper nanoparticle is attached. The organic capping ligand may include a mercaptocarboxyiic acid. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 18/014244 |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) H01B 13/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261268 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army DEVCOM, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lin Ma (Silver Spring, Maryland); Marshall A. Schroeder (Pasadena, Maryland); Oleg A. Borodin (Laurel, Maryland); Travis P. Pollard (Rockville, Maryland); Kang Xu (Potomac, Maryland) |
| ABSTRACT | To improve the performance of certain multivalent metal electrodes, the electrodes can be treated prior to use in an electrochemical cell by applying a solution comprising an acid to a surface of a multivalent metal electrode, then removing excess solution comprising the acid and drying the surface of the multivalent metal electrode. The resulting electrode has an outer interphase layer comprised of a hydrated hydroxychloride comprising the multivalent metal, where the interphase layer has a thickness of less than 5 µm. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/583303 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) H01M 4/485 (20130101) H01M 10/38 (20130101) Original (OR) Class H01M 10/365 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261385 | He et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xuanke He (Atlanta, Georgia); Emmanouil Tentzeris (Atlanta, Georgia); Ryan Alexander Bahr (Peachtree City, Georgia); Yunnan Fang (Atlanta, Georgia) |
| ABSTRACT | An antenna system includes an antenna waveguide having a waveguide surface. A set of printed electronics includes conductors deposited onto the waveguide surface of the antenna waveguide. The system further includes at least one transceiver integrated circuit (IC), the transceiver integrated circuit having a surface assembly, wherein the surface assembly is adhesively coupled to the antenna waveguide and directly connected to the waveguide surface of the antenna waveguide. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 17/405661 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/364 (20130101) H01Q 1/2283 (20130101) H01Q 13/18 (20130101) H01Q 13/0233 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261428 | Richardson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Martin Richardson (Orlando, Florida); Robert Bernath (Orlando, Florida); Nathan Bodnar (Orlando, Florida); Haley Kerrigan (Orlando, Florida); Danielle Reyes (Orlando, Florida); Daniel Thul (Orlando, Florida); Jessica Pena (Orlando, Florida) |
| ABSTRACT | A laser system may include one or more seed lasers to generate a pulsed seed beam. The system may further include a pulse pattern generator to generate an intermediate patterned burst-mode beam from at least one laser pulse from the pulsed seed beam, where the intermediate patterned burst-mode beam includes one or more pulse bursts, and where each of the one or more pulse bursts includes a series of laser pulses with a selected pattern of inter-pulse spacings. The system may further include two or more power amplifiers to amplify the intermediate patterned burst-mode beam to form an amplified patterned burst-mode beam, where at least two of the power amplifiers amplify different portions of the intermediate patterned burst-mode beam, and where the amplified patterned burst-mode beam includes a series of amplified pulse bursts including amplified laser pulses with the selected pattern of inter-pulse spacings. |
| FILED | Monday, November 07, 2022 |
| APPL NO | 17/981738 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) Original (OR) Class H01S 3/2308 (20130101) H01S 3/10023 (20130101) H01S 3/10084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261442 | Meyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlinggton, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Jerry R. Meyer (Catonsville, Maryland); Alexander Spott (Santa Barbara, California); Vijaysekhar Jayaraman (Goleta, California); Chul Soo Kim (West Springfield, Virginia); Mijin Kim (West Springfield, Virginia); Chadwick L. Canedy (Washington, District of Columbia); Charles D. Merritt (Fairfax, Virginia); William W. Bewley (Falls Church, Virginia); Igor Vurgaftman (Severna Park, Maryland) |
| ABSTRACT | Semiconductor laser architectures that provide weak index guiding of interband cascade lasers (ICLs) processed on a native III-V substrate and of ICLs grown on GaAs or integrated on GaAs by heterogeneous bonding. Weak index guiding of a ridge waveguide semiconductor laser can enhance the stability of lasing in the fundamental lateral mode, so as to allow a wider ridge to maintain stable single-lateral-mode operation. |
| FILED | Wednesday, February 08, 2023 |
| APPL NO | 18/165956 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/11 (20210101) H01S 5/12 (20130101) H01S 5/183 (20130101) H01S 5/223 (20130101) Original (OR) Class H01S 5/343 (20130101) H01S 5/3402 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261462 | Zhang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Di Zhang (Carmel, California) |
| ABSTRACT | A Solid-State Circuit Breaker Device and Method Without Current Limiting Inductor. According to an exemplary embodiment of this disclosure, described is a high-density, high-efficiency megawatt (MW) medium-voltage (MV) solid-state circuit breaker (SSCB) for, example only, aviation hybrid electric propulsion applications. The SSCB is based on the mature silicon (Si) insulated gate bipolar transistor (IGBT) devices. With reduced IGBT gate voltage, the disclosed SSCB can limit the peak fault current without the fault current limiting inductor. Thus, the specific power density of the SSCB is substantially improved compared with the traditional design. |
| FILED | Monday, February 27, 2023 |
| APPL NO | 18/114655 |
| CURRENT CPC | Emergency Protective Circuit Arrangements H02H 9/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261693 | Dafesh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Philip A. Dafesh (Manhattan Beach, California); Phillip Brian Hess (Venice, California); Gourav K. Khadge (Los Angeles, California) |
| ABSTRACT | Provided herein are circuits and methods for processing samples of a received in-phase and quadrature (I/Q) domain signal that includes a desired signal and an interference signal that spectrally overlaps the desired signal. In the I/Q domain, a first contribution to the interference signal is removed from the samples using a first algorithm to generate first processed signal samples. Amplitudes and phases of the first processed signal samples are obtained. In an amplitude domain, a second contribution to the interference signal is removed from the amplitudes of the first processed signal samples using a second algorithm to generate second processed signal samples. A signal quality metric of the second processed signal samples is obtained. Based on the signal quality metric of the second processed signal samples, one or more parameters of the first or second algorithm are adjusted to improve the signal quality metric of the second processed signal samples. |
| FILED | Tuesday, February 07, 2023 |
| APPL NO | 18/165594 |
| CURRENT CPC | Transmission H04B 1/719 (20130101) H04B 1/1027 (20130101) H04B 1/1036 (20130101) H04B 1/7107 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261762 | Brodsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army DEVCOM, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Brodsky (Millburn, New Jersey); Cristian Antonelli (Sulmona, Italy); Daniel E. Jones (Nottingham, Maryland); Gabriele Riccardi (Roma, Italy) |
| ABSTRACT | Systems, apparatus and methods for defining an impairment profile along a polarization quantum channel such as in terms of modal loss and decoherence. The disclosed impairment profile or characterization methods may be used as part of a tool such as to inform a network operator of a weakest span of the communication channel, thus facilitating optimal signal routing decisions. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/100857 |
| CURRENT CPC | Transmission H04B 10/70 (20130101) Original (OR) Class H04B 10/079 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261764 | PETERSEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | L3Harris Technologies, Inc. (Melbourne, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy PETERSEN (Camden, New Jersey); Richard WINSLOW (Fort Wayne, Indiana) |
| ABSTRACT | Techniques of present disclosure are directed to methods of providing acoustic communication networks. For example, methods are provided for that include obtaining, at a first transceiver of a plurality of transceivers arranged within an installation pattern, a first acoustic signal provided by a second transceiver of the plurality of transceivers. A location of the first transceiver within a message distribution pattern is determined from the acoustic signal. A delay based upon the location of the first transceiver within the message distribution pattern is determined. Finally, a second acoustic signal corresponding to the first acoustic signal is provided from the first transceiver after the delay. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/669606 |
| CURRENT CPC | Transmission H04B 11/00 (20130101) Original (OR) Class H04B 13/02 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0428 (20130101) Wireless Communication Networks H04W 64/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261873 | Khoury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joud Khoury (Boston, Massachusetts); Michael Hassan Atighetchi (Framingham, Massachusetts); Zachary Ratliff (Somerville, Massachusetts) |
| ABSTRACT | Techniques for verifiable computation for cross-domain information sharing are disclosed. An untrusted node in a distributed cross-domain solution (CDS) system is configured to: receive a first data item and a first cryptographic proof associated with the first data item; perform a computation on the first data item including one or more of filtering, sanitizing, or validating the first data item, to obtain a second data item; generate, using a proof-carrying data (PCD) computation, a second cryptographic proof that indicates (a) validity of the first cryptographic proof and (b) integrity of the first computation on the first data item; and transmits the second data item and the second cryptographic proof to a recipient node in the distributed CDS system. Alternatively or additionally, the untrusted node may be configured to transmit a cryptographic proof to a trusted aggregator in the CDS system. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/138399 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3218 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230262036 | HUA |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yingbo HUA (Riverside, California) |
| ABSTRACT | A communication network may comprise: a first communication node configured for, based on a first association with a vector, encrypting information to be transmitted; a transmitter circuitry configured for transmitting the encrypted information; a receiver circuitry configured for receiving the transmitted encrypted information; a second communication node configured for, based on a second association with the vector, decrypting the received encrypted information. The vector may be a physical-layer feature vector or a common feature vector. The encryption and decryption may be based on linear or nonlinear encryption functions. A nonlinear encryption function may have an output that is based on a singular value decomposition of an input. The encryption and decryption may apply to security over networks, including for wireless communications or biometric templates. |
| FILED | Wednesday, October 26, 2022 |
| APPL NO | 17/974422 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0485 (20130101) Original (OR) Class Wireless Communication Networks H04W 12/03 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230262073 | SHEU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Ray-Yuan SHEU (Bel Air, Maryland); Shawn Paul JOHNSON (Columbia, Maryland); Cory HALL (Severn, Maryland); Ronald Wayne ALFORD (Vienna, Virginia); James Raymond MORRIS-KING (Acton, Massachusetts) |
| ABSTRACT | Described herein are systems and methods for generating a cyber-deception strategy that adaptively implement a decoy file placement strategy for thwarting malicious activity on a computing network. The systems and methods can include a plurality of surveillance services that can monitor the evolving conditions and states of a target computing network. The information from the external surveillance services can be combined with one or more user defined parameters to serve as inputs to a system that can use the input data to generate a decoy file content and placement strategy so as to effect a cyber-deception strategy. In one or more examples, can identify one or more target objects to use as decoys and use the identified targeted objects as well as information about the target network, to generate a high-level guidelines that will be used to generate one or more deception plans for implementation on the target network. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/671203 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/6218 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230262077 | Palmer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CFD Research Corporation (Huntsville, Alabama) |
| ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
| INVENTOR(S) | Brian Gene Palmer (Huntsville, Alabama) |
| ABSTRACT | The present invention includes systems and methods for providing cybersecurity to web-enabled applications for protection of critical software and host systems. The present invention is operable to build a Hidden Markov model of an application using automated analysis of code and documentation in order to characterize potential state and state transitions. The present invention is also operable to use additional data such as timing and proximity to assess incoming data. Incoming messages are then assigned a trust score based on Bayesian calculations. |
| FILED | Tuesday, November 08, 2022 |
| APPL NO | 17/983048 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0245 (20130101) H04L 63/1416 (20130101) H04L 63/1425 (20130101) Original (OR) Class H04L 63/1441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230262899 | Gerasopoulos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Konstantinos Gerasopoulos (Gambrills, Maryland); Jason E. Tiffany (Columbia, Maryland); Seppo J. Lehtonen (Columbia, Maryland); Vanessa O. Rojas (Columbia, Maryland); Spencer A. Langevin (Silver Spring, Maryland); Bing Tan (Ann Arbor, Michigan) |
| ABSTRACT | An apparatus for mounting on a circuit board is provided. The apparatus may include a circuit board mount packaging and a battery. The circuit board mount packaging may include a cavity, a first internal lead, and a second internal lead. The first internal lead may be connect to a first external pin and the second internal lead may be connected to a second external pin. The battery may be disposed within the cavity of the circuit board mount packaging. The battery may comprise an anode and a cathode. The anode may be wire bond connected to the first internal lead and the cathode may be wire bond connected to the second internal lead. |
| FILED | Friday, December 16, 2022 |
| APPL NO | 18/082924 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0431 (20130101) H01M 10/0468 (20130101) H01M 10/6569 (20150401) H01M 50/105 (20210101) H01M 50/519 (20210101) H01M 2300/0082 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) Original (OR) Class H05K 2201/10037 (20130101) H05K 2201/10568 (20130101) H05K 2201/10628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230262902 | Cox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Functional Fabrics of America, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Cox (Ashland, Massachusetts); Tairan Wang (Chelmsford, Massachusetts); Tsachi Avrahami (Arlington, Massachusetts); Charlotte Fairless (Watertown, Massachusetts); Jennifer Thornton (Cambridge, Massachusetts); Mary Jane Schmuhl (Cambridge, Massachusetts); Henry Cheung (Cambridge, Massachusetts); Bruce Thompson (Boston, Massachusetts); Emily Robertson (Somerville, Massachusetts) |
| ABSTRACT | A system for incorporating electronic functionality into a flexible layer includes a flexible printed circuit board having a spine portion and one or more legs in electronic communication with the spine portion. Multiple pads may be disposed on the flexible printed circuit board. The spine portion and the one or more legs may be structured and arranged to be disposed within one or more pockets of the flexible layer. The system may further include electronic devices, each one of which may be in electronic communication with at least one of the pads. In addition, the system may include a controller in electronic communication with at least one of the pads. The system may be characterized by an absence of any external hard-wire interfaces for communication external to the system. |
| FILED | Wednesday, March 29, 2023 |
| APPL NO | 18/192385 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/038 (20130101) H05K 1/111 (20130101) H05K 1/189 (20130101) Original (OR) Class H05K 3/36 (20130101) H05K 2201/052 (20130101) H05K 2201/09972 (20130101) H05K 2201/10098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230256422 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fanxing Li (Raleigh, North Carolina); Xijun Wang (Raleigh, North Carolina); Emily Krzystowczyk (Raleigh, North Carolina); Jian Dou (Raleigh, North Carolina); Yunfei Gao (Raleigh, North Carolina) |
| ABSTRACT | In one aspect, the disclosure relates to an oxygen-deficient mixed metal perovskite having the formula SrxA1-xFeyB1-yO3-δ, wherein A can be Ca, K, Y, Ba, La, Sm, or any combination thereof; wherein B can be Co, Cu, Mn, Mg, Ni, Ti, or any combination thereof; wherein x is from 0 to 1; wherein y is from 0 to 1; and wherein δ is from 0 to 0.7. Also disclosed are redox catalysts comprising the oxygen-deficient mixed metal perovskites and methods for chemical looping air separation, chemical looping CO2 splitting, and chemical looping alkane conversion using the disclosed catalysts. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/167159 |
| CURRENT CPC | Separation B01D 53/8671 (20130101) B01D 2255/402 (20130101) B01D 2255/2022 (20130101) B01D 2255/2042 (20130101) B01D 2255/2045 (20130101) B01D 2255/2047 (20130101) B01D 2255/2073 (20130101) B01D 2255/20738 (20130101) B01D 2255/20746 (20130101) B01D 2255/20753 (20130101) B01D 2257/104 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/002 (20130101) B01J 23/78 (20130101) Original (OR) Class B01J 23/83 (20130101) B01J 23/8892 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/40 (20130101) C01B 32/40 (20170801) C01B 2203/0261 (20130101) C01B 2203/1058 (20130101) C01B 2203/1241 (20130101) Acyclic or Carbocyclic Compounds C07C 5/42 (20130101) C07C 2523/78 (20130101) C07C 2523/83 (20130101) C07C 2523/889 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257173 | HARRIS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tequila A. HARRIS (Atlanta, Georgia); Tae Joong JEONG (Atlanta, Georgia); Yue JI (Atlanta, Georgia); Kwangjun JUNG (Atlanta, Georgia); James Carson MEREDITH (Atlanta, Georgia) |
| ABSTRACT | An exemplary embodiment of the present disclosure provides a membrane including a supporting base layer, which can be permeable, and a dual layer oxygen barrier film disposable over the supporting base layer. The supporting barrier film can include a polymeric or paper-based material. The dual layer oxygen barrier film can include a chitin material and a cellulosic material. The cellulosic material of the dual layer oxygen barrier film can be the same material as the permeable membrane or can be any other cellulosic material |
| FILED | Tuesday, February 28, 2023 |
| APPL NO | 18/176075 |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 65/42 (20130101) Original (OR) Class B65D 2565/387 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257759 | MALIK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YIELD10 BIOSCIENCE, INC. (Woburn, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Meghna MALIK (Saskatoon, Canada); Jihong TANG (West Roxbury, Massachusetts); Yuanyuan JI (Saskatoon, Canada); Venkatesh BOLLINA (Saskatoon, Canada); Lifeng CHEN (Saskatoon, Canada); Marie MYKYTYSHYN (Saskatoon, Canada); Kristi D. SNELL (Belmont, Massachusetts) |
| ABSTRACT | A genetically modified plant that exhibits an increase in seed yield relative to a progenitor plant is provided. The genetically modified plant includes: (a) a first biotin attachment domain-containing (badc) gene, occurring in its natural position within the genome and being homozygous for a wild-type allele: (b) a second badc gene, occurring in its natural position within the genome and being homozygous for a mutant allele; (c) one or more homologs of the first badc gene, each occurring in its natural position within the genome and being homozygous for a wild-type allele; and (d) one or more homologs of the second badc gene, each occurring in its natural position within the genome, and at least one being homozygous for a wild-type allele. The mutant allele does not encode a functional BADC protein. The increase in seed yield is at least 4%. |
| FILED | Thursday, August 12, 2021 |
| APPL NO | 18/005302 |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/10 (20130101) A01H 6/20 (20180501) Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8247 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257781 | Church et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Kevin M. Esvelt (Auburndale, Massachusetts); Prashant G. Mali (La Jolla, California) |
| ABSTRACT | Methods of modulating expression of a target nucleic acid in a cell are provided including use of multiple orthogonal Cas9 proteins to simultaneously and independently regulate corresponding genes or simultaneously and independently edit corresponding genes. |
| FILED | Thursday, April 06, 2023 |
| APPL NO | 18/296446 |
| CURRENT CPC | Peptides C07K 2/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/85 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/3519 (20130101) C12N 2320/33 (20130101) C12N 2320/50 (20130101) C12N 2800/40 (20130101) C12N 2800/80 (20130101) C12N 2800/107 (20130101) C12N 2810/10 (20130101) C12N 2830/00 (20130101) C12N 2830/34 (20130101) C12N 2999/007 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257791 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Lynch (Durham, North Carolina); John Decker (Durham, North Carolina) |
| ABSTRACT | Methods and kits are provided for producing Griffithsin. The methods include providing a genetically modified microorganism comprising a gene encoding Griffithsin protein operably linked to an inducible promotor and growing the genetically modified microorganism under conditions that induce the promotor and cause expression of griffithisin. The Griffithsin is purified by releasing Griffithsin from the microorganism by cellular disruption, performing a precipitation step to remove contaminating protein and nucleic acids, and performing an anion exchange chromatography step. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/906501 |
| CURRENT CPC | Peptides C07K 14/405 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/635 (20130101) C12N 2800/101 (20130101) C12N 2830/002 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257794 | Debnath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Anik Debnath (Cambridge, Massachusetts); George M. Church (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are artificial secretion peptides capable of directing secretion from Lactobacillus for use, for example, in producing heterologous proteins, including therapeutic proteins. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055044 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/747 (20130101) A61K 2035/115 (20130101) Peptides C07K 14/605 (20130101) C07K 14/4723 (20130101) C07K 14/5428 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/746 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258234 | Shu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Deming Shu (Darien, Illinois); Steven P. Kearney (Schaumburg, Illinois); Jayson W. Anton (Chicago, Illinois); Ross J. Harder (Downers Grove, Illinois); Xianbo Shi (Naperville, Illinois); Tim M. Mooney (Westmont, Illinois); Lahsen Assoufid (Chicago, Illinois) |
| ABSTRACT | The present disclosure relates to a flexure mechanism that includes a plurality of thin material structures, each thin material structure including a weak-link portion and a separable constraint portion. The separable constraint portion is linked to the weak-link portion and configured to stabilize the weak-link portion. Additionally, the plurality of thin material structures are stacked and secured together to form a laminar structure. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673737 |
| CURRENT CPC | Couplings for Transmitting Rotation; Clutches; Brakes F16D 3/79 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258484 | Senderos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Bruno Zamorano Senderos (Huntsville, Alabama); Ali Yousefiani (Tustin, California); Austin E. Mann (Chesterfield, Missouri); Michael F. Stoia (Rancho Santa Margarita, California) |
| ABSTRACT | A material compatibility test design system and method, allowing for the testing of characteristics of behavior of materials in extreme environments, the method including concurrently exposing a test specimen to a first environment and a second environment, the test specimen having an outside surface and an inside surface, the inside surface defining an internal volume, includes exposing the outside surface of the test specimen to the first environment for a predetermined period of time, the first environment comprising a first temperature, a first pressure and a first composition. The method further includes exposing the inside surface of the test specimen to the second environment for a second predetermined period of time, the second environment comprising a second temperature, a second pressure and a second composition. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673085 |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 21/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 37/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258507 | SKIFTON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard S. SKIFTON (Idaho Falls, Idaho); Douglas A. CORBETT (Rigby, Idaho) |
| ABSTRACT | A thermocouple may have a first thermoelement wire formed of a first material and a first sheath covering at least part of the first thermoelement wire. The first sheath may provide thermal insulation and may be formed of a third material, different from the first material, that is subject to oxidation in response to exposure to a surrounding material. The thermocouple may further have a second sheath covering at least a first portion of the first sheath. The second sheath may act as a barrier between the first portion of the first sheath and the surrounding material and may be formed of a fourth material that is resistant to oxidation in the surrounding material. The first thermoelement wire may be joined, at a junction, with one of the first sheath, and a second thermoelement wire formed of a second material different from the first material. |
| FILED | Monday, February 13, 2023 |
| APPL NO | 18/109193 |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/06 (20130101) Original (OR) Class G01K 7/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258523 | Dark |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Phillip Ryan Dark (Kansas City, Kansas) |
| ABSTRACT | A method of testing a sensing device with a sensing mass includes accelerating the sensing device along a circular path about a central axis. The sensing mass of the sensing device may be movable relative to the central axis. The method includes determining a position of the sensing mass of the sensing device via a sensor and shifting the sensing device radially relative to the central axis based at least in part on the position of the sensing mass during acceleration. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/672794 |
| CURRENT CPC | Centrifuges B04B 9/146 (20130101) B04B 13/00 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 1/32 (20130101) Original (OR) Class Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258733 | Gering et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin L. Gering (Idaho Falls, Idaho); Zonggen Yi (Idaho Falls, Idaho); Sangwook Kim (Idaho Falls, Idaho) |
| ABSTRACT | Embodiments disclosed herein include methods, systems and/or devices configured to generate historical parameters of a sigmoidal rate expression based on the sigmoidal rate expression and measured data of a battery. The embodiments may further be configured to predict future parameters of the sigmoidal rate expression based on the sigmoidal rate expression and the historical parameters. The embodiments may further be configured to predict an aging state of the battery based on the sigmoidal rate expression and the future parameters. Additional embodiments are directed to methods, systems, and/or devices configured to synthesize training data based on measured battery data, a sigmoidal rate expression, and ranges for parameters of the sigmoidal rate expression. The additional embodiments may further be configured to train a machine-learning model using the synthesized training data. |
| FILED | Thursday, February 16, 2023 |
| APPL NO | 18/170471 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/367 (20190101) G01R 31/389 (20190101) G01R 31/392 (20190101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230259340 | RAVISHANKAR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIDIA Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mahesh RAVISHANKAR (Bothell, Washington); Vinod GROVER (Mercer Island, Washington); Evghenii GABUROV (Santa Clara, California); Alberto MAGNI (Cambridge, United Kingdom); Sean Youngsung LEE (Bothell, Washington) |
| ABSTRACT | A computation graph is accessed. In the computation graph, operations to be performed are represented as interior nodes, inputs to the operations are represented as leaf nodes, and a result of the operations is represented as a root. Selected sets of the operations are combined to form respective kernels of operations. Code is generated execute the kernels of operations. The code is executed to determine the result. |
| FILED | Friday, April 14, 2023 |
| APPL NO | 18/134919 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/443 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230259768 | Fronk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Ryan G. Fronk (Idaho Falls, Idaho); Matthew W. Anderson (Idaho Falls, Idaho); Michael A. Reichenberger (Idaho Falls, Idaho); Dawn M. Scates (Idaho Falls, Idaho); Edward L. Reber (Idaho Falls, Idaho) |
| ABSTRACT | The present disclosure describes aspects of a machine-learned (ML) spectrum analysis configured to distinguish between a plurality of radioisotope types and/or a plurality of emission levels of respective radioisotope types within spectrum data. The ML spectrum analyzer may utilize an artificial neural network (ANN) having an output layer configured to produce prediction data for respective labels, each label corresponding to a respective radioisotope. The prediction data may be configured to quantify an amount of each respective radioisotope within a subject of the spectrum. |
| FILED | Friday, February 03, 2023 |
| APPL NO | 18/164145 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 5/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230259783 | Suski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Applied Engineering Concepts, Inc. (Eldersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Charles Suski (Mount Pleasant, South Carolina); Christopher Alan Card (Sykesville, Maryland); Brian Richard Few (Sykesville, Maryland) |
| ABSTRACT | A network authentication system can be configured for sampling a plurality of signal samples from a device on a network, providing the plurality of signal samples to a first machine-learned model that is configured to determine a device fingerprint based at least in part on the plurality of signal samples, and providing the device fingerprint to a second machine-learned model that is configured to classify the device based at least in part on the device fingerprint. |
| FILED | Wednesday, April 19, 2023 |
| APPL NO | 18/303119 |
| CURRENT CPC | Electric Digital Data Processing G06F 18/214 (20230101) G06F 18/2411 (20230101) G06F 18/24765 (20230101) Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) G06N 3/084 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/764 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260602 | Sankaranarayanan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | Uchicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Subramanian Sankaranarayanan (Naperville, Illinois); Troy David Loeffler (Chicago, Illinois); Henry Chan (Schaumburg, Illinois); Mathew J. Cherukara (Darien, Illinois); Srilok Srinivasan (Woodridge, Illinois) |
| ABSTRACT | A system can include one or more processors configured to access at least one parameter of a material, generate a plurality of structures of the material using the at least one parameter, determine a state of each structure of the plurality of structures using the at least one parameter, determine a difference between the state of each structure of the plurality of structures and a ground state value, evaluate a convergence condition responsive to determining the difference between the state of each structure of the plurality of structures and the ground state value, and output at least one structure of the plurality of structures responsive to the convergence condition being satisfied. |
| FILED | Tuesday, April 25, 2023 |
| APPL NO | 18/138827 |
| CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/00 (20190201) G16C 20/30 (20190201) Original (OR) Class G16C 20/70 (20190201) G16C 20/80 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260717 | ZHU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Board of Trustees of Northern Illinois University (DeKalb, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kai ZHU (Littleton, Colorado); Fei ZHANG (Tianjin, China PRC); Tao XU (Naperville, Illinois) |
| ABSTRACT | The present disclosure relates to a device that includes a first layer having an active material and a stabilizing material, where the active material includes a semiconductor, the stabilizing material includes at least one of an oligomer, an elastomer, a polymer, and/or a resin, and the stabilizing material provides to the device an improved performance metric compared to a device constructed of the first layer but constructed of only the active material (i.e., in the absence of the stabilizing material). |
| FILED | Tuesday, April 25, 2023 |
| APPL NO | 18/306576 |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0036 (20130101) H01G 9/2009 (20130101) Original (OR) Class Organic electric solid-state devices H10K 30/30 (20230201) H10K 30/40 (20230201) H10K 71/12 (20230201) H10K 85/30 (20230201) H10K 85/40 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260736 | Elam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); INCOM, INC. (Charlton, Maryland) |
| INVENTOR(S) | Jeffrey W. Elam (Elmhurst, Illinois); Anil U. Mane (Naperville, Illinois); Mark Popecki (Durham, New Hampshire); Michael Minot (Andover, Massachusetts) |
| ABSTRACT | A secondary electron emissive layer resistant to infiltration and fouling. A barrier layer is formed by atomic layer deposition. The barrier layer may be an emissive layer and/or an interlayer. The barrier layer may form an interlayer that is a part of an electron amplifier positioned between an emissive layer and a resistive layer. The barrier layer is resistive to fluorine migration from either the emissive layer or the resistive layer. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/671135 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45527 (20130101) C23C 16/45553 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 9/42 (20130101) H01J 9/125 (20130101) Original (OR) Class H01J 43/246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260772 | Cooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Zane Baird (West Lafayette, Indiana); Wen-Ping Peng (Hualien, Taiwan) |
| ABSTRACT | The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure. |
| FILED | Friday, April 14, 2023 |
| APPL NO | 18/134887 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/06 (20130101) H01J 49/10 (20130101) H01J 49/26 (20130101) H01J 49/067 (20130101) Original (OR) Class H01J 49/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261124 | KUANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | RENSSELAER POLYTECHNIC INSTITUTE (TROY, New York) |
| INVENTOR(S) | Ping KUANG (Latham, New York); Shawn Yu LIN (Troy, New York); Anthony POST (Catskill, New York); Sajeev Oommen JOHN (Mississauga, Canada); Sergey Leonidovich EYDERMAN (Toronto, Canada); Mei-Li HSIEH (MiaoLi County, Taiwan) |
| ABSTRACT | A high absorption photovoltaic material and method of making the material for use in a solar cell are disclosed. The photovoltaic material includes a surface modified with a layer of repeating photonic crystal structures. The photonic crystal structures are approximately inverse conically shaped and have a curved sidewall that has an approximately Gaussian shape. The photonic crystal structures generally have a high vertical depth and sidewall angle. The structures also have a gradient refractive index profile and exhibit the parallel-to-interface refraction light trapping effect. An anti-reflective coating is disposed over the photonic crystal structure layer. The photovoltaic material exhibits near unity light absorption over a broad range of visible and near infrared wavelengths and incidence angles, even at reduced thicknesses. The photovoltaic structures are formed via a combined photolithography and reactive-ion etching method at low power with a gas mixture having a high ratio of an etchant component to a passivation component. |
| FILED | Thursday, April 20, 2023 |
| APPL NO | 18/136988 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/02168 (20130101) H01L 31/02363 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261211 | Fang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation For the State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jiye Fang (Vestal, New York); Ming Zhou (Binghamton, New York) |
| ABSTRACT | A fuel cell catalyst, including: one or more substantially monodisperse nanocrystals, wherein the one or more substantially monodisperse nanocrystals include an octahedral morphology or nanocrystal geometry including eight exclusively exposed {101} facets. In embodiments, a cathode including the fuel cell catalyst is also provided, including methods of making the fuel cell catalyst. |
| FILED | Wednesday, December 14, 2022 |
| APPL NO | 18/081485 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8882 (20130101) H01M 4/9016 (20130101) Original (OR) Class H01M 8/083 (20130101) H01M 2004/8689 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261690 | WENTZLOFF et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David WENTZLOFF (Ann Arbor, Michigan); Milad MOOSAVIFAR (Ann Arbor, Michigan); Jaeho IM (Ann Arbor, Michigan) |
| ABSTRACT | A dual chirp modulation technique is presented for use in telecommunications. The technique includes: generating a first chirp signal ramping at a first rate; generating a second chirp signal ramping at a second rate which differs from the first rate; combining the first chirp signal with the second chirp signal to form a dual chirped signal; and transmitting, the dual chirped signal from a transmitter to a receiver. At least one first chirp signal, the second chirp signal or the dual chirped signal is preferably modulated. At the receiver, the dual chirped signal is correlated with a local chirp signal to help reject out-of-band interferers. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/672877 |
| CURRENT CPC | Transmission H04B 1/04 (20130101) H04B 1/692 (20130101) Original (OR) Class H04B 2001/6912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261922 | Moradi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hussein Moradi (Idaho Falls, Idaho); Thomas C. Sego (Idaho Falls, Idaho); Behrouz Farhang (Salt Lake City, Utah) |
| ABSTRACT | Systems, devices, and methods are described for multi-band spread spectrum communication. A communication system, which may include any number of communication nodes, may include a first communication node including a dedicated first number of subcarrier bands, and a second communication node including a dedicated second number of subcarrier bands. The first communication node may be configured to transmit a link request to the second communication node over the first number of subcarrier bands, and the second communication node may be configured to transmit another link request to the first communication node over the second number of subcarrier bands. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/168808 |
| CURRENT CPC | Transmission H04B 1/69 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/26416 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230262867 | Yatom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Shurik Yatom (Lawrenceville, New Jersey); Yevgeny Raitses (Princeton, New Jersey); Sophia Gershmann (Scotch Plains, New Jersey); Phillip Efthimion (Bedminster, New Jersey) |
| ABSTRACT | Disclosed are dielectric barrier discharge (DBD) devices and methods of use for sterilizing surfaces. The DBD devices generally include one or more first electrodes, one or more second electrodes or chemical reagent layers, and at least one dielectric layer between the one or more first electrodes and the one or more second electrodes or chemical reagent layers. In various configurations, the at least one dielectric layer is either (a) in contact with at least one of the first electrodes or (if present) at least one chemical reagent layer, or (b) is separated from the one or more first electrodes by a first gap and is also separated from the one or more second electrodes or chemical reagent layers by a second gap. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/669622 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/14 (20130101) A61L 2202/11 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/2406 (20130101) Original (OR) Class H05H 2245/40 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230262997 | Hammond et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); SolarWindow Technologies, Inc. (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott R. Hammond (Wheat Ridge, Colorado); Marinus Franciscus Antonius Maria van Hest (Golden, Colorado); John A. Conklin (Apalachin, New York) |
| ABSTRACT | Visually undistorted thin film electronic devices are provided. In one embodiment, a method for producing a thin-film electronic device comprises: opening a scribe in a stack of thin film material layers deposited on a substrate to define an active region and an inactive region of the thin-film electronic device, the stack comprising at least one active semiconductor layer. The active region comprises a non-scribed area of the stack and the inactive region comprises a region of the stack where thin film material was removed by the scribe. The method further comprises depositing at least one scribe fill material into a gap opened by the scribe. The scribe fill material has embedded therein one or more coloring elements that alter an optical characteristics spectrum of the inactive region to obtain an optical characteristics spectrum of the active region within a minimum perceptible difference for an industry defined standard observer. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/164834 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0465 (20141201) Organic electric solid-state devices H10K 30/80 (20230201) Original (OR) Class H10K 39/10 (20230201) H10K 71/00 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263002 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian Li (Tempe, Arizona); Tyler Fleetham (Gilbert, Arizona) |
| ABSTRACT | A light emitting device includes a first electrode, a hole transporting layer in contact with the first electrode, a second electrode, an electron transporting layer in contact with the second electrode; and an emissive layer between the hole transporting layer and the electron transporting layer. The emissive layer includes a phosphorescent emitter, a fluorescent emitter, and a host, and the phosphorescent emitter harvests electrogenerated excitons and transfers energy to the fluorescent emitter. |
| FILED | Wednesday, April 19, 2023 |
| APPL NO | 18/302880 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/185 (20130101) C09K 2211/1011 (20130101) C09K 2211/1029 (20130101) Organic electric solid-state devices H10K 50/11 (20230201) H10K 50/17 (20230201) H10K 50/121 (20230201) H10K 50/156 (20230201) Original (OR) Class H10K 50/166 (20230201) H10K 85/6572 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263062 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shanhui Fan (Stanford, California); Lingling Fan (Stanford, California); Wei Li (Palo Alto, California); Meir Orenstein (Haifa, Israel) |
| ABSTRACT | In certain examples, methods, apparatuses and semiconductor-related structures are directed to nighttime-like electrical power generation by use of a spectro-angular selective emitter as an optimal radiative cooler and a thermoelectric power generator (TEG) having a hot side and a cold side. The cold side may be coupled to the spectro-angular selective emitter which is directed to or facing an atmosphere characterized by an absence of solar light. Power may be generated via the TEG based on energy directed from the spectro-angular selective emitter and by controlling or limiting ability of the spectro-angular selective emitter to absorb heat power at frequencies and/or angles where emission of the atmosphere is dominant. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 18/015010 |
| CURRENT CPC | Electric solid-state devices not otherwise provided for H10N 10/17 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230256422 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fanxing Li (Raleigh, North Carolina); Xijun Wang (Raleigh, North Carolina); Emily Krzystowczyk (Raleigh, North Carolina); Jian Dou (Raleigh, North Carolina); Yunfei Gao (Raleigh, North Carolina) |
| ABSTRACT | In one aspect, the disclosure relates to an oxygen-deficient mixed metal perovskite having the formula SrxA1-xFeyB1-yO3-δ, wherein A can be Ca, K, Y, Ba, La, Sm, or any combination thereof; wherein B can be Co, Cu, Mn, Mg, Ni, Ti, or any combination thereof; wherein x is from 0 to 1; wherein y is from 0 to 1; and wherein δ is from 0 to 0.7. Also disclosed are redox catalysts comprising the oxygen-deficient mixed metal perovskites and methods for chemical looping air separation, chemical looping CO2 splitting, and chemical looping alkane conversion using the disclosed catalysts. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/167159 |
| CURRENT CPC | Separation B01D 53/8671 (20130101) B01D 2255/402 (20130101) B01D 2255/2022 (20130101) B01D 2255/2042 (20130101) B01D 2255/2045 (20130101) B01D 2255/2047 (20130101) B01D 2255/2073 (20130101) B01D 2255/20738 (20130101) B01D 2255/20746 (20130101) B01D 2255/20753 (20130101) B01D 2257/104 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/002 (20130101) B01J 23/78 (20130101) Original (OR) Class B01J 23/83 (20130101) B01J 23/8892 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/40 (20130101) C01B 32/40 (20170801) C01B 2203/0261 (20130101) C01B 2203/1058 (20130101) C01B 2203/1241 (20130101) Acyclic or Carbocyclic Compounds C07C 5/42 (20130101) C07C 2523/78 (20130101) C07C 2523/83 (20130101) C07C 2523/889 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230256442 — SYSTEMS AND METHODS FOR TRAPPING AND TRANSPORTING SMALL PARTICLES WITH ACOUSTIC FORCES
| US 20230256442 | Cummer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven Cummer (Durham, North Carolina); Junfei Li (Durham, North Carolina); Chen Shen (Durham, North Carolina) |
| ABSTRACT | The present disclosure describes systems and methods for versatile acoustic tweezer trapping and transport configurations. Examples can use ultrasound for contact-free, biocompatible, and precise manipulation of particles from millimeter to sub-micrometer scale along a narrow and complex path. Examples include spatially complex particle trapping and manipulation inside a boundary-free chamber using a single pair of sources and a shadow waveguide. The shadow waveguide structure can be disposed just outside a microfluidic chamber to guide and control the acoustic wave fields inside the chamber. The shadow waveguide can create a tightly confined, spatially complex acoustic field inside the chamber without an interior structure that could interfere with net flow or transport. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/111176 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2300/14 (20130101) B01L 2300/168 (20130101) B01L 2400/049 (20130101) B01L 2400/0439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256668 | Nishida et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (GAINESVILLE, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Toshikazu Nishida (Gainesville, Florida); Aftab Bhanvadia (Gainesville, Florida) |
| ABSTRACT | Described herein are stereolithographic methods for preparing 3D objects comprising hollow regions and/or multiple materials. In certain embodiments, the methods comprise applying a blocking composition to fill hollow regions in the 3D printed object. In certain embodiments, an absorbent is applied to dispense material into the 3D printed objects and to remove unwanted resin from the hollow regions. Additionally, in certain embodiments, the modular stereolithographic apparatuses described herein contain an invertible, double vat, which enables users easy access to multiple materials throughout the 3D printing process. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/167194 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/40 (20170801) B29C 64/135 (20170801) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 50/02 (20141201) B33Y 70/10 (20200101) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257271 | Adamson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Douglas H. Adamson (Mansfield Center, Connecticut); Richard Parnas (Ashford, Connecticut); Prabodha Abeykoon (Willimantic, Connecticut) |
| ABSTRACT | Systems and methods are provided that may utilize a glass substrate to selectively withdraw exfoliated graphene from a high-energy interface between immiscible solvents. The exfoliated graphene preferentially adheres to the surface of the glass substrate for withdrawal from the noted high energy interface, leaving behind the graphite (which is too large to be effectively adsorbed relative to the glass substrate). The disclosed systems and methods are easily implemented and offer significant advantages for graphene production relative to conventional systems and methods, e.g., the disclosed systems/methods do not require the input of heat or mechanical energy which translates to processes that are both cheaper to run and do not result in damage to the graphene. Still further, the disclosed systems/methods do not require chemical modification of the graphene, again lowering the cost considerably and not damaging the graphene structure. |
| FILED | Thursday, February 17, 2022 |
| APPL NO | 17/674389 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/19 (20170801) Original (OR) Class Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 25/44 (20130101) C03C 2218/328 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257322 | VOUTCHKOVA-KOSTAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adelina M. VOUTCHKOVA-KOSTAL (Washington, District of Columbia); Diana AINEMBABAZI (Washington, District of Columbia); Darren DOLAN (Washington, District of Columbia); Jonathan HORLYCK (Washington, District of Columbia) |
| ABSTRACT | The present disclosure relates to a process for preparing long-chain alkanes and alkenes from alcohols, aldehydes, or both. The process proceeds via acceptorless dehydrogenation and decarbonylative coupling using a supported catalyst. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/168738 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/44 (20130101) B01J 35/023 (20130101) Acyclic or Carbocyclic Compounds C07C 1/24 (20130101) Original (OR) Class C07C 2523/44 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) C10L 2200/0469 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257755 | Easley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Auburn University (Auburn, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher J. Easley (Auburn, Alabama); Subramaniam Somasundaram (Auburn, Alabama) |
| ABSTRACT | Described herein are DNA-nanostructures that can be used in an assay to detect and/or quantify an analyte of interest. Aspects of the DNA-nanostructure can include a single DNA molecule composed of hairpin structural motifs, an anchor recognition moiety, and a signal moiety, where the anchor recognition moiety and the signal moiety are in effective proximity to each other such that the tethered diffusion of the signal molecule can be altered based upon binding status of the anchor recognition moiety. Also described herein are methods of making and using the DNA-nanostructures. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/158466 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/122 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 2565/518 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257764 | SCHULTINK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fortiphyte, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Fortiphyte, Inc. (Berkeley, California) |
| INVENTOR(S) | Alexander Christiaan SCHULTINK (Berkeley, California); Laura A. WETZEL (Berkeley, California) |
| ABSTRACT | The present disclosure provides an isolated, recombinant, or synthetic polynucleotide comprising a FIT1 protein, and homologs, fragments, and variations thereof. The disclosure further relates to transgenic plants, plant parts, and plant cells comprising one or more of these polynucleotides, and exhibit resistance or tolerance to a pathogen, such as Phakopsora pachyrhizi. The disclosure further relates to methods of genetically engineering a pathogen resistance or tolerance trait in a plant, plant part, or plant cell, comprising targeted gene editing of a FIT1 homolog, and plants produced therefrom. The disclosure further relates to methods for identifying new functional FIT1 genes and/or alleles thereof. |
| FILED | Tuesday, December 06, 2022 |
| APPL NO | 18/062538 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/8282 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257907 | REN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Zhifeng REN (Pearland, Texas); Jiming BAO (Pearland, Texas); Shuai YUE (Pearland, Texas); Fei TIAN (Richmond, Texas); Geethal Amila Udalamatta GAMAGE (Fremont, California); Gang CHEN (Carlisle, Massachusetts); Jungwoo SHIN (Cambridge, Massachusetts) |
| ABSTRACT | Herein provided are cubic boron arsenide (c-BAs) single crystals having an unexpectedly high ambipolar mobility at room temperature, µa, at one or more locations thereof that is greater than or equal to 1500, 1600, 1700, 1800, 1900, 2000, 2100, 2200, 2300, 2400, 2500, 2600, 3000, 4000, 5000, 6000, 7000, 8000, 9000, or 10000 cm2V-1s-1, wherein the ambipolar mobility is defined as: µa = 2µeµh/(µe + µh), wherein µe is electron mobility and µh is hole mobility, and having a room temperature thermal conductivity at the one or more locations thereof that is greater than or equal to 1000 Wm-1K-1. Methods of making and using the c-BAs single crystals are also provided. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/100291 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/04 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/76 (20130101) C01P 2002/82 (20130101) C01P 2002/84 (20130101) C01P 2004/02 (20130101) C01P 2004/03 (20130101) C01P 2006/32 (20130101) C01P 2006/40 (20130101) C01P 2006/80 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/16 (20130101) C30B 25/18 (20130101) C30B 29/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258154 | Hong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jiarong Hong (New Brighton, Minnesota); Linyue Gao (Minneapolis, Minnesota) |
| ABSTRACT | Control systems are described that mitigate the effects of icing events on wind turbines. Example methods include determining, with a control system, that an icing event has begun to affect the wind turbine; based on a determination that the icing event has begun to affect the wind turbine, changing a phase of the wind turbine with the control system to an operational-icing phase by modifying angles of attack of blades of the wind turbine via changing blade pitch angles, wherein the wind turbine continues to generate electrical power when the wind turbine is in the operational-icing phase; and based on a determination that electrical power generation of the wind turbine is below a threshold, changing the phase of the wind turbine with the control system to a stopped-icing phase, wherein rotation of the blades of the wind turbine is halted when the wind turbine is in the stopped-icing phase. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 18/005549 |
| CURRENT CPC | Wind Motors F03D 7/0224 (20130101) Original (OR) Class F03D 80/40 (20160501) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2270/328 (20130101) F05B 2270/335 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258203 | Keplinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Christoph Matthias Keplinger (Gerlingen, Germany); Xingrui Wang (Boulder, Colorado); Shane Karl Mitchell (Boulder, Colorado) |
| ABSTRACT | High strain hydraulically amplified self-healing electrostatic transducers having increased maximum theoretical and practical strains are disclosed. In particular, the actuators include electrode configurations having a zipping front created by the attraction of the electrodes that is configured orthogonally to a strain axis along which the actuators. This configuration produces increased strains. In turn, various form factors for the actuator configuration are presented including an artificial circular muscle and a strain amplifying pulley system. Other actuator configurations are contemplated that include independent and opposed electrode pairs to create cyclic activation, hybrid electrode configurations, and use of strain limiting layers for controlled deflection of the actuator. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/138621 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1075 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 5/006 (20130101) Original (OR) Class F15B 15/103 (20130101) F15B 21/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258204 | Do et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian H. Do (Plant City, Florida); Inrak Choi (Seoul, South Korea); Sean Weston Follmer (Palo Alto, California) |
| ABSTRACT | A variable impedance actuator is provided with a bladder-style actuator having a first end and a second end, and a jamming brake located inside the bladder-style actuator and connected to the first end and the second end of the bladder-style actuator. The bladder-style actuator and the jamming brake are independently controlled. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109432 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1075 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258603 | DULANEY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Liminal Insights, Inc. (Emeryville, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Austin Ryan DULANEY (Emeryville, California); Jason Yue YU (Castro Valley, California); Shaurjo BISWAS (El Cerrito, California); Andrew G. HSIEH (Berkeley, California); Barry J. VAN TASELL (El Cerrito, California) |
| ABSTRACT | The present disclosure are directed to techniques for defect detection and identification inside batteries. In one aspect, a non-invasive method of identifying and labeling defects in a battery cell includes transmitting acoustic signals through a battery cell via one or more first transducers, receiving response signals in response to the acoustic signals at one or more second transducers, determining whether at least one feature of interest exists in the battery cell based on analyzing the response signals, performing an identification and labeling process on the at least one feature of interest to determine at least one defect in the battery cell, and outputting a result of the identification and labeling process. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109521 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/048 (20130101) G01N 29/069 (20130101) Original (OR) Class G01N 29/4445 (20130101) G01N 29/4481 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/4285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258608 | YU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Liminal Insights, Inc. (EMERYVILLE, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Yue YU (Castro Valley, California); Shaurjo BISWAS (El Cerrito, California); Yu Shi FONG (Emeryville, California); Dennis YU (Alameda, California); Andrew HSIEH (Berkeley, California); Ashlyn Leona D'ORAZIO (Berkeley, California); Austin Ryan DULANEY (Emeryville, California) |
| ABSTRACT | Aspects of the present disclosure are directed to a suite of testing apparatuses and non-destructive, acoustic inspection methods for scanning and inspecting batteries to determine and characterize various physical phenomena in these batteries. In one aspect, a rastering system for non-invasive and acoustic inspection of battery cells includes a holder for placing a battery cell inside the system for the acoustic inspection, at least one transducer configured to perform acoustic measurements on the battery cell, and a controller configured with inspection parameters for performing the acoustic measurements, the inspection parameters being dynamic and interchangeable depending on at least one or more of a shape, a size, and a form factor of the battery cell. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109482 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/04 (20130101) G01N 29/44 (20130101) G01N 29/265 (20130101) Original (OR) Class G01N 2291/023 (20130101) G01N 2291/106 (20130101) G01N 2291/0289 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258630 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuebing Zheng (Austin, Texas); Youngsun Kim (Austin, Texas) |
| ABSTRACT | Disclosed herein are devices, systems, and methods for analyte sensing with optothermally generated bubbles in biphasic liquid samples. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 18/015808 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 33/56983 (20130101) G01N 2201/06 (20130101) G01N 2333/11 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258640 | DEMPSEY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HAWKEYE BIO, LIMITED (Dublin, Ireland); THE UNIVERSITY OF KANSAS (Lawrence, Kansas); KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (Manhattan, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul W. DEMPSEY (Los Angeles, California); Spencer HANTULA (Long Beach, California); Cristina-Mihaela Sandu APARICIO (Laguna Hills, California); Stefan H. BOSSMANN (Kansas City, Missouri); Christopher M. SORENSEN (Manhattan, Kansas); Obdulia COVARRUBIAS-ZAMBRANO (Lenexa, Kansas); Jose COVARRUBIAS (Manhattan, Kansas) |
| ABSTRACT | Provided herein are graphene biosensors and related core particles, compositions methods and systems in which more than one pristine graphene sheet is coated with a coating layer of an organic or inorganic material to provide a core graphene particle, to which detectable components comprising a detectable moiety and a peptide linkage are attached through binding of the peptide linkage. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 18/051422 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) G01N 33/542 (20130101) G01N 33/551 (20130101) G01N 33/573 (20130101) Original (OR) Class G01N 33/54346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258788 | Vienneau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emelina Prevost Vienneau (Walnut Cove, North Carolina); Brett C. Byram (Brentwood, Tennessee) |
| ABSTRACT | One aspect of the invention relates to method and system for increasing signal-to-noise ratio (SNR) and suppressing range lobe artifacts in ultrasound imaging or sensing, active sonar, LIDAR, and/or radar. The method includes forming a coded excitation waveform with a chip waveform and a binary sequence; transmitting the coded excitation waveform into a medium of interest, and receiving signals generated from the medium of interest responsive to excitation of the coded excitation waveform; and performing pulse compression on the received signals using a decoding filter to increase the SNR and suppress the range lobe artifacts. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 18/024315 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52026 (20130101) Original (OR) Class G01S 7/52047 (20130101) G01S 15/104 (20130101) G01S 15/8961 (20130101) G01S 15/8979 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230259212 | Zhakypov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhenishbek Zhakypov (Mountain View, California); Allison M. Okamura (Mountain View, California) |
| ABSTRACT | A fully 3-D printed, soft, monolithic 4-DoF fingertip haptic technology is provided, called FingerPrint, that stimulates linear and rotational shear, pressure, and vibration on the fingerpad. Constructed using an origami waterbomb base mechanism and printed from a flexible material, the device embeds four sets of eight foldable vacuum-powered pneumatic actuators to achieve three translational (x, y, z) and one rotational (torsion) tactile motions and forces of a tactor end-effector on the fingerpad skin. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109417 |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/18 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Electric Digital Data Processing G06F 3/016 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230259635 | Bao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona); University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tiffany Bao (Tempe, Arizona); Connor Nelson (Tempe, Arizona); Zhuoer Lyu (Phoenix, Arizona); Tudor Dumitras (College Park, Maryland); Octavian Suciu (College Park, Maryland) |
| ABSTRACT | A computer-implemented system incorporates a time-varying view of exploitability in the form of Expected Exploitability (EE) to learn and continuously estimate the likelihood of functional software exploits being developed over time. The system characterizes the noise-generating process systematically affecting exploit prediction, and applies a domain-specific technique (e.g., Feature Forward Correction) to learn EE in the presence of label noise. The system also incorporates timeliness and predictive utility of various artifacts, including new and complementary features from proof-of-concepts, and includes scalable feature extractors. The system is validated on three case studies to investigate the practical utility of EE, showing that the system incorporating EE can qualitatively improve prioritization strategies based on exploitability. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169674 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/577 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230259806 | BRINGEWATT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); Government of the United States of America as Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob BRINGEWATT (Hyattsville, Maryland); Przemyslaw BIENIAS (San Francisco, California); Timothy QIAN (Rockville, Maryland); Igor BOETTCHER (Washington, District of Columbia); Alexey GORSHKOV (Potomac, Maryland) |
| ABSTRACT | A system for the measurement of field properties includes a quantum system, a processor, and a memory. The quantum system includes a plurality of quantum sensors coupled to a field. Each sensor of the plurality of quantum sensors is located at a position in the field. The position depends on parameters. Each sensor of the plurality of quantum sensors is entangled. The memory includes instructions stored thereon, which, when executed by the processor, cause the quantum system to: access a signal of the quantum system; sense a plurality of interdependent a local field amplitudes corresponding to the plurality of quantum sensors by locally probing the field by each sensor of the plurality of quantum sensors; estimate a function of the parameters at a position x0, where x0 is a position without a quantum sensor of the plurality of quantum sensors; and estimate an amplitude of the field at the position x0 based on the estimated function of the parameters. |
| FILED | Tuesday, November 01, 2022 |
| APPL NO | 17/978420 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) G06N 10/70 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261786 | Guo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Nian Guo (Pasadena, California); Victoria Kostina (Pasadena, California) |
| ABSTRACT | Systems and methods for performing real-time feedback communication in accordance with various embodiments of the invention are disclosed. In many embodiments, instantaneous encoding is utilized for transmitting symbols from a streaming source over a DMC with feedback. In certain embodiments, instantaneous encoding is performed during the arriving period of the symbols. At time t, the encoder and the decoder calculate the priors of possible symbol sequences using the source distribution and the posteriors at time t−1. In a number of embodiments, the encoder and decoder then partition the evolving message alphabet into groups, so that the group priors are close to the capacity-achieving distribution. In contrast to the SED rule for symmetric binary-input channels, partitioning processes in accordance with several embodiments of the invention utilize group priors instead of group posteriors for the partitioning. In many embodiments, once the groups are partitioned, the encoder determines the index of the group that contains the true symbol sequence it received so far and uses the group index to determine the appropriate channel input. |
| FILED | Friday, February 03, 2023 |
| APPL NO | 18/164462 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/1555 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0057 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230262054 | MARASCO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGE MASON UNIVERSITY (FAIRFAX, Virginia) |
| ASSIGNEE(S) | GEORGE MASON UNIVERSITY (FAIRFAX, Virginia) |
| INVENTOR(S) | EMANUELA MARASCO (ALEXANDRIA, Virginia); MASSIMILIANO ALBANESE (POTOMAC, Maryland) |
| ABSTRACT | A method of authenticating a user that includes initializing the multi-factor authentication system based on an input; presenting a challenge requesting the user to enter a specific authenticator of a sequence of authenticators stored in the multi-factor authentication system, where the stored sequence of authenticators represents a combination of a plurality of authentication factors; receiving an authenticator from the user in response to the challenge; verifying identity of the user by determining whether the received authenticator matches the specific authenticator requested by the challenge; and granting the access based on a determination that the received authenticator matches the specific authenticator requested, or denying the access based on a determination that the received authenticator does not match the specific authenticator requested. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/670590 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/083 (20130101) H04L 63/102 (20130101) H04L 63/0861 (20130101) Original (OR) Class H04L 2463/082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20230256430 | Gagnon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachary Richard Gagnon (College Station, Texas); Md Nazibul Islam (College Station, Texas) |
| ABSTRACT | A method for producing a microfluidic device includes creating a paper channel using a cutting device (e.g., a laser cutter, scissors, dies, blade, or the like), placing the paper channel between two sheets of PDMS, treating the PDMS sheets with a corona plasma to adhere the PDMS sheets together, and using heat to laminate the microfluidic device. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/920929 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502707 (20130101) Original (OR) Class B01L 2200/0694 (20130101) B01L 2300/126 (20130101) B01L 2300/0645 (20130101) B01L 2300/0867 (20130101) B01L 2300/0883 (20130101) B01L 2300/0887 (20130101) B01L 2400/0406 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258203 | Keplinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Christoph Matthias Keplinger (Gerlingen, Germany); Xingrui Wang (Boulder, Colorado); Shane Karl Mitchell (Boulder, Colorado) |
| ABSTRACT | High strain hydraulically amplified self-healing electrostatic transducers having increased maximum theoretical and practical strains are disclosed. In particular, the actuators include electrode configurations having a zipping front created by the attraction of the electrodes that is configured orthogonally to a strain axis along which the actuators. This configuration produces increased strains. In turn, various form factors for the actuator configuration are presented including an artificial circular muscle and a strain amplifying pulley system. Other actuator configurations are contemplated that include independent and opposed electrode pairs to create cyclic activation, hybrid electrode configurations, and use of strain limiting layers for controlled deflection of the actuator. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/138621 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1075 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 5/006 (20130101) Original (OR) Class F15B 15/103 (20130101) F15B 21/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258630 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuebing Zheng (Austin, Texas); Youngsun Kim (Austin, Texas) |
| ABSTRACT | Disclosed herein are devices, systems, and methods for analyte sensing with optothermally generated bubbles in biphasic liquid samples. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 18/015808 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 33/56983 (20130101) G01N 2201/06 (20130101) G01N 2333/11 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260297 | Currier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert D. Currier (Beverly Hills, Florida); Barbara A. Kirkpatrick (Sarasota, Florida) |
| ABSTRACT | Portable imaging and taxa classification systems and methods are described. One such method comprises accessing at least one microscopic image captured using an imaging device and a microscope from memory and executing a machine learning (ML) routine on the at least one computing device using a single image frame of the at least one microscopic image as an input to identify a presence of a taxa. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/170872 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/87 (20220101) G06V 10/764 (20220101) G06V 20/695 (20220101) G06V 20/698 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260670 | Hughes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ColdQuanta, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven Michael Hughes (Louisville, Colorado); Christopher Robert Sheridan, III (Boulder, Colorado) |
| ABSTRACT | A drop-in multi-optics module for a quantum-particle (e.g., rubidium, cesium) cell provides for more convenient and cost-effective manufacture of such cells (including vacuum cells, cold/ultra-cold matter cells, vapor cells, and channel cells). In a 3D printing approach, a model of a frame augmented by buffer material is 3D printed. The buffer material is removed from the augmented frame to achieved desired dimensions with greater precision than could be achieved by 3D printing the frame directly. Optical and, in some cases, other components are attached to the frame to realize the multi-optics drop-in module. Alternatively, the module can be formed by cutting out portions of a metal sheet and then folding the resulting 2D preform. |
| FILED | Tuesday, October 04, 2022 |
| APPL NO | 17/959979 |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260680 | Hammig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Hammig (Dexter, Michigan); Nicholas Kotov (Ann Arbor, Michigan); Jing Lyu (Beijing, China PRC); Suneel Joglekar (West Lafayette, Indiana) |
| ABSTRACT | A method of fabricating a conductor includes preparing an aramid nanofiber solution in which a matrix of aramid nanofibers is dispersed, preparing a dispersion of copper nanoparticles, each copper nanoparticle of the dispersion of cooper nanoparticles having an organic capping ligand attached to the copper nanoparticle, and incorporating copper nanoparticles of the dispersion of copper nanoparticles into the matrix of aramid nanofibers such that each incorporated copper nanoparticle is bonded to a respective aramid nanofiber of the matrix of aramid nanofibers via the organic capping ligand to which the copper nanoparticle is attached. The organic capping ligand may include a mercaptocarboxyiic acid. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 18/014244 |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) H01B 13/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230261210 | JONES et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John-Paul JONES (Pasadena, California); Scott N. ROBERTS (Pasadena, California); Keith J. BILLINGS (Pasadena, California); Douglas C. HOFMANN (Pasadena, California); Samad A. FIRDOSY (Pasadena, California); Sarah D. LUDEMAN (Pasadena, California) |
| ABSTRACT | A monolithic electrode structure for use in electrochemical flow cells is presented. The monolithic electrode structure includes a dense region with embedded flow channels that provides functionality of a flow field layer and a porous region that provides combined functionalities of gas diffusion and catalyst layers. The monolithic electrode structure is additively fabricated to include regions of different porosities/densities. A material of the monolithic electrode structure is a pure metal that is a catalyst for a targeted electrochemical reaction, or an alloy that contains such pure metal. Porosity of the porous region is adjusted to allow flow of liquid, such as water, towards or away from an active surface of the electrode. According to one aspect, porosity is adjusted by adjusting the pore size that make the porous region. According to another aspect, the dense region contains cooling channels for cooling of the electrode. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/167697 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/28 (20210101) B22F 10/366 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/861 (20130101) H01M 4/8636 (20130101) H01M 4/8807 (20130101) H01M 4/8825 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20230257857 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chuan Liu (Evanston, Illinois); Gregory B. Olson (Riverswood, Illinois) |
| ABSTRACT | The invention relates to a precipitation-strengthened shape memory alloy (SMA) comprising a composition designed and processed such that the precipitation-strengthened SMA meets property objectives comprising a yield strength being more than about 1500 MPa at room temperature, a transformation temperature in a range of about −15 to 20° C., a misfit in a range of about 0.9-1.1%, wherein the property objectives are design specifications of the precipitation-strengthened SMA. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109379 |
| CURRENT CPC | Alloys C22C 30/00 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/002 (20130101) C22F 1/006 (20130101) C22F 1/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230259804 | GRZESIAK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IONQ, INC. (College Park, Maryland); University of Maryland (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | NIKODEM GRZESIAK (College Park, Maryland); Andrii Maksymov (Hyattsville, Maryland); Pradeep Niroula (College Park, Maryland); Yunseong Nam (North Bethesda, Maryland) |
| ABSTRACT | A method of performing computation using an ion trap quantum computing system including a classical computer, a system controller, and a quantum processor includes computing, by the classical computer, a circuit that implements a selected set of gate operations, using one or more efficient arbitrary simultaneous entangling (EASE) gates, implementing, by the system controller, the computed circuit on the quantum processor, measuring, by the system controller, population of qubit states in the quantum processor, and outputting, by the classical computer, the measured population of qubit states in the quantum processor. |
| FILED | Monday, July 11, 2022 |
| APPL NO | 17/862039 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class G06N 10/80 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230259806 | BRINGEWATT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); Government of the United States of America as Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob BRINGEWATT (Hyattsville, Maryland); Przemyslaw BIENIAS (San Francisco, California); Timothy QIAN (Rockville, Maryland); Igor BOETTCHER (Washington, District of Columbia); Alexey GORSHKOV (Potomac, Maryland) |
| ABSTRACT | A system for the measurement of field properties includes a quantum system, a processor, and a memory. The quantum system includes a plurality of quantum sensors coupled to a field. Each sensor of the plurality of quantum sensors is located at a position in the field. The position depends on parameters. Each sensor of the plurality of quantum sensors is entangled. The memory includes instructions stored thereon, which, when executed by the processor, cause the quantum system to: access a signal of the quantum system; sense a plurality of interdependent a local field amplitudes corresponding to the plurality of quantum sensors by locally probing the field by each sensor of the plurality of quantum sensors; estimate a function of the parameters at a position x0, where x0 is a position without a quantum sensor of the plurality of quantum sensors; and estimate an amplitude of the field at the position x0 based on the estimated function of the parameters. |
| FILED | Tuesday, November 01, 2022 |
| APPL NO | 17/978420 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) G06N 10/70 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230260297 | Currier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert D. Currier (Beverly Hills, Florida); Barbara A. Kirkpatrick (Sarasota, Florida) |
| ABSTRACT | Portable imaging and taxa classification systems and methods are described. One such method comprises accessing at least one microscopic image captured using an imaging device and a microscope from memory and executing a machine learning (ML) routine on the at least one computing device using a single image frame of the at least one microscopic image as an input to identify a presence of a taxa. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/170872 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/87 (20220101) G06V 10/764 (20220101) G06V 20/695 (20220101) G06V 20/698 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230255478 | Abramoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael D. Abramoff (University Heights, Iowa); Meindert Niemeijer (Iowa City, Iowa); Xiayu Xu (Iowa City, Iowa); Milan Sonka (Coralville, Iowa); Joseph M. Reinhardt (Iowa City, Iowa) |
| ABSTRACT | The methods and systems provided can automatically determine an Arteriolar-to-Venular diameter Ratio, AVR, in blood vessels, such as retinal blood vessels and other blood vessels in vertebrates. The AVR is an important predictor of increases in the risk for stroke, cerebral atrophy, cognitive decline, and myocardial infarct. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/185704 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) Original (OR) Class A61B 3/0016 (20130101) A61B 3/0058 (20130101) A61B 3/1225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255825 | KOONER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Karanjit S. KOONER (Plano, Texas); Michael A. MONG (Grapevine, Texas); Ghadeer AL-HUMIMAT (Dallas, Texas); Jacob A. AWKAL (Plano, Texas); Hebah G. ABDALLAH (Carrollton, Texas); Nguyen L. LE (Richardson, Texas); Jamasp AZARNOOSH (Dallas, Texas); Peter Dirk Jan REYNTJENS (Richardson, Texas); Jeremy L. WARREN (El Paso, Texas) |
| ABSTRACT | A shunt operable to be implanted on an eye is provided. The shunt includes a vein fluidic channel operable to be in fluid communication with an interior of the eye and operable to receive aqueous fluid from the interior of the eye. A body is fluidly coupled with the vein fluidic channel. A valve is disposed within the body and is operable to regulate intraocular pressure in the eye by opening and closing based on pressure from the aqueous fluid. A plurality of outlets are in fluid communication with the body opposite the vein fluidic channel in relation to the valve. The outlets are operable to release the aqueous fluid to the sclera of the eye. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 18/000671 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/00781 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230255948 | Morser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of The Leland Stanford Junior University (Stanford, California); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael J. Morser (San Francisco, California); Lawrence L.K Leung (Hillsborough, California); Timothy Myles (Sunnyvale, California) |
| ABSTRACT | Methods for treating cancer using combination therapy with an anti-coagulant and a B-Raf inhibitor and/or a mitogen-activated protein kinase (MEK) inhibitor are disclosed. The anti-coagulant may be a direct inhibitor of thrombin or an indirect inhibitor of thrombin, such as an inhibitor of factor Xa, factor XIa, or other coagulation factors. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 18/014971 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4439 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257480 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Chris Yang (Stanford, California); Anton Wyss-Coray (Stanford, California) |
| ABSTRACT | Provided herein are methods and compositions for increasing blood-brain barrier permeability in a subject to enhance blood-brain barrier drug transport and methods and composition for identifying agents that regulate blood-brain barrier permeability. |
| FILED | Thursday, December 03, 2020 |
| APPL NO | 17/782501 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/40 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Enzymes C12Y 301/03001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20230255493 | HILLMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Elizabeth M.C. HILLMAN (New York, New York); Sean A. BURGESS (New York, New York) |
| ABSTRACT | Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM). |
| FILED | Friday, April 14, 2023 |
| APPL NO | 18/134805 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0064 (20130101) Original (OR) Class A61B 5/0066 (20130101) A61B 5/0071 (20130101) A61B 5/0073 (20130101) A61B 5/0075 (20130101) A61B 5/0088 (20130101) A61B 5/444 (20130101) A61B 5/445 (20130101) A61B 2562/0238 (20130101) A61B 2562/0242 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) G01J 3/457 (20130101) G01J 3/2889 (20130101) Optical Elements, Systems, or Apparatus G02B 23/2476 (20130101) G02B 26/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256137 | Martinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ViaCyte, Inc. (San Diego, California) |
| ASSIGNEE(S) | ViaCyte, Inc. (San Diego, California) |
| INVENTOR(S) | Laura Martinson (San Diego, California); Chad Green (San Diego, California); Evert Kroon (San Diego, California); Emmanuel Edward Baetge (San Diego, California) |
| ABSTRACT | The present invention relates to methods for encapsulating pancreatic progenitors in a biocompatible semi-permeable encapsulating device. The present invention also relates to production of human insulin in a mammal in response to glucose stimulation. |
| FILED | Tuesday, April 25, 2023 |
| APPL NO | 18/138904 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/022 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/39 (20130101) A61K 38/28 (20130101) A61K 2035/126 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/14 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/3804 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/00 (20130101) A61M 31/00 (20130101) A61M 31/002 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0676 (20130101) C12N 5/0678 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257598 | BOWMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG INDUSTRIES OHIO, INC. (CLEVELAND, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MARK PAUL BOWMAN (NEW KENSINGTON, Pennsylvania); VENICE POMTILA AKELO MAGUNGA (NEWARK, Delaware); LUCAS MANUEL DOS SANTOS FREIRE (PITTSBURGH, Pennsylvania) |
| ABSTRACT | A rubber coating layer is prepared from a sprayable aqueous coating dispersion including: a rubber dispersion including a rubber binder dispersed in an aqueous medium, a sulfur-containing vulcanization agent, and a platy inorganic material. The coating dispersion or a film formed from the coating dispersion is vulcanized at a temperature of from 100° C. to less than 160° C. for up to 1 hour to form the rubber coating layer having a melt temperature of greater than 60° C. A sprayable pre-vulcanized coating dispersion is prepared from a coating dispersion including: a rubber dispersion comprising a rubber binder dispersed in an aqueous medium, a sulfur-containing vulcanization agent, and a platy inorganic material. The coating dispersion is vulcanized at a temperature of from 70° C. to less than the boiling point of the aqueous medium to form the pre-vulcanized coating dispersion. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055062 |
| CURRENT CPC | Treatment or Chemical Modification of Rubbers C08C 19/14 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/48 (20180101) Original (OR) Class C09D 7/61 (20180101) C09D 7/65 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230257907 | REN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Zhifeng REN (Pearland, Texas); Jiming BAO (Pearland, Texas); Shuai YUE (Pearland, Texas); Fei TIAN (Richmond, Texas); Geethal Amila Udalamatta GAMAGE (Fremont, California); Gang CHEN (Carlisle, Massachusetts); Jungwoo SHIN (Cambridge, Massachusetts) |
| ABSTRACT | Herein provided are cubic boron arsenide (c-BAs) single crystals having an unexpectedly high ambipolar mobility at room temperature, µa, at one or more locations thereof that is greater than or equal to 1500, 1600, 1700, 1800, 1900, 2000, 2100, 2200, 2300, 2400, 2500, 2600, 3000, 4000, 5000, 6000, 7000, 8000, 9000, or 10000 cm2V-1s-1, wherein the ambipolar mobility is defined as: µa = 2µeµh/(µe + µh), wherein µe is electron mobility and µh is hole mobility, and having a room temperature thermal conductivity at the one or more locations thereof that is greater than or equal to 1000 Wm-1K-1. Methods of making and using the c-BAs single crystals are also provided. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/100291 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/04 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/76 (20130101) C01P 2002/82 (20130101) C01P 2002/84 (20130101) C01P 2004/02 (20130101) C01P 2004/03 (20130101) C01P 2006/32 (20130101) C01P 2006/40 (20130101) C01P 2006/80 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/16 (20130101) C30B 25/18 (20130101) C30B 29/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20230255219 | CUTTER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Catherine N. CUTTER (State College, Pennsylvania); Abdelrahim H.A. HASSAN (Beni-Suef, Egypt) |
| ABSTRACT | Provided are composite antimicrobial and laminar antimicrobial materials that are suitable for use with food packaging. The materials may be edible, recyclable, or biodegradable materials. Methods for making the materials, uses of the materials, and products that pertain to the materials are included. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/780716 |
| CURRENT CPC | Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 4/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230256071 | Lawrence et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mississippi State University (Starkville, Mississippi) |
| ASSIGNEE(S) | Mississippi State University (Starkville, Mississippi) |
| INVENTOR(S) | Mark L. Lawrence (Starkville, Mississippi); Attila Karsi (Starkville, Mississippi); Hossam Abdelhamed (Starkville, Mississippi) |
| ABSTRACT | Aeromonas hydrophila is a reemerging pathogen of channel catfish (Ictalurus punctatus); recent outbreaks from 2009 to 2014 have caused the loss of more than 12 million pounds of market size catfish in Alabama and Mississippi. Genome sequencing revealed a clonal group of A. hydrophila isolates with unique genetic and phenotypic features that is highly pathogenic in channel catfish. Comparison of the genome sequence of a representative catfish isolate (ML09-119) from this virulent clonal group with lower virulence A. hydrophila isolates revealed four fimbrial proteins unique to strain ML09-119. In this work, we expressed and purified four A. hydrophila fimbrial proteins (FimA, Fim, MrfG, and FimOM) and assessed their ability to protect and stimulate protective immunity in channel catfish fingerlings against A. hydrophila ML09-119 infection for vaccine development. Our results showed catfish immunized with FimA, Fim, FimMrfG, and FimOM exhibited 59.83%, 95.41%, 85.72%, and 75.01% relative percent survival, respectively, after challenge with A. hydrophila strain ML09-119. Bacterial concentrations in liver, spleen, and anterior kidney were significantly (p < 0.05) lower in vaccinated fish compared to the non-vaccinated sham groups at 48 h post-infection. However, only the Fim immunized group showed a significantly higher antibody titer in comparison to the non-vaccinated treatment group (p < 0.05) at 21 days post-vaccination. Altogether, Fim and FimMrfG recombinant proteins have potential for vaccine development against virulent A. hydrophila infection. Genomic subtraction revealed three outer membrane proteins present in strain ML09-119 but not in the low virulence reference A. hydrophila strain; the major outer membrane protein OmpAI (OmpA1), TonB-dependent receptor (TonB-DR), and transferrin-binding protein A (TbpA). Here, the genes encoding OmpAI, tonB-DR, and tbpA were cloned from A. hydrophila ML09-119 and were expressed into Escherichia coli. The purified recombinant OmpA, TonB-DR, and TbpA proteins had estimated molecular weights of 37.26, 78.55, and 41.67 kDa, respectively. Catfish fingerlings vaccinated with OmpA1, TonB-DR, and TbpA emulsified with non-mineral oil adjuvant were protected against the subsequent A. hydrophila ML09-119 infection with 98.59%, 95.59%, and 47.89% relative percent survival (RPS), respectively. Furthermore, the mean liver, spleen, and anterior kidney bacterial loads were significantly lower in catfish vaccinated with the OmpA1 and TonB-DR than the non-vaccinated control group. ELISA demonstrated that catfish immunized with OmpA1, TonB-DR, and TbpA produce significant antibody response by 21 days post-immunization. Therefore, data generated during the study suggest that OmpAI and TonB-DR proteins could be used as potential candidates for vaccine development against A. hydrophila epidemic strain infection. However, TbpA protein failed to provide such strong protection. Recombinant ATPase from A. hydrophila also showed promise as a vaccine antigen. A live attenuated vaccine was prepared that combined the advantages of a live attenuated vaccine (ESC-NDKL1 (ΔgcvPΔsdhCΔƒtdA) mutant of Edwardsiella ictaluri) against enteric septicemia of catfish (ESC) and three immunogenic recombinant proteins (Fim, FimMrfg, and ATPase) against A. hydrophila infection. Our results showed channel catfish fingerlings immersion-vaccinated with ESC-NDKL1::pETfim, ESC-NDKL1::pETmrfG, and ESC-NDKL1::pETATPase exhibited 100%, 91.67%, and 100% percent survival after challenge with the A. hydrophila ML09-119, which was significantly less than non-vaccinated group (88.89% mortality). In a second study, Catfish immunized with NDKL1::pETfim, ESC-NDKL1::pETmrfG, ESC-NDKL1::pETATPase had significantly (p < 0.05) lower mortalities than sham-vaccinated group. |
| FILED | Tuesday, May 31, 2022 |
| APPL NO | 17/829033 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/025 (20130101) A61K 39/0208 (20130101) Original (OR) Class A61K 2039/522 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230258603 | DULANEY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Liminal Insights, Inc. (Emeryville, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Austin Ryan DULANEY (Emeryville, California); Jason Yue YU (Castro Valley, California); Shaurjo BISWAS (El Cerrito, California); Andrew G. HSIEH (Berkeley, California); Barry J. VAN TASELL (El Cerrito, California) |
| ABSTRACT | The present disclosure are directed to techniques for defect detection and identification inside batteries. In one aspect, a non-invasive method of identifying and labeling defects in a battery cell includes transmitting acoustic signals through a battery cell via one or more first transducers, receiving response signals in response to the acoustic signals at one or more second transducers, determining whether at least one feature of interest exists in the battery cell based on analyzing the response signals, performing an identification and labeling process on the at least one feature of interest to determine at least one defect in the battery cell, and outputting a result of the identification and labeling process. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109521 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/048 (20130101) G01N 29/069 (20130101) Original (OR) Class G01N 29/4445 (20130101) G01N 29/4481 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/4285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230258608 | YU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Liminal Insights, Inc. (EMERYVILLE, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Yue YU (Castro Valley, California); Shaurjo BISWAS (El Cerrito, California); Yu Shi FONG (Emeryville, California); Dennis YU (Alameda, California); Andrew HSIEH (Berkeley, California); Ashlyn Leona D'ORAZIO (Berkeley, California); Austin Ryan DULANEY (Emeryville, California) |
| ABSTRACT | Aspects of the present disclosure are directed to a suite of testing apparatuses and non-destructive, acoustic inspection methods for scanning and inspecting batteries to determine and characterize various physical phenomena in these batteries. In one aspect, a rastering system for non-invasive and acoustic inspection of battery cells includes a holder for placing a battery cell inside the system for the acoustic inspection, at least one transducer configured to perform acoustic measurements on the battery cell, and a controller configured with inspection parameters for performing the acoustic measurements, the inspection parameters being dynamic and interchangeable depending on at least one or more of a shape, a size, and a form factor of the battery cell. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109482 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/04 (20130101) G01N 29/44 (20130101) G01N 29/265 (20130101) Original (OR) Class G01N 2291/023 (20130101) G01N 2291/106 (20130101) G01N 2291/0289 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20230260349 | Hastings et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as Represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | William Hastings (Billings, Montana); James Gilkeson (Alexandria, Virginia); Douglas MacIvor (Arlington, Virginia) |
| ABSTRACT | Various embodiments of the present invention are directed toward systems and methods relating to security screening. For example, a screening system includes a chamber configured to accommodate a user to be screened, and a chamber scanner. The chamber scanner is configured to scan the user to identify whether the user is carrying an undivested item that needs to be divested. The chamber is configured to release the user to proceed from the chamber to a secure area, upon confirmation that no undivested items are to be divested. |
| FILED | Thursday, February 02, 2023 |
| APPL NO | 18/105055 |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0041 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/28 (20200101) Original (OR) Class Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 20230258443 | Vabnick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federal Bureau of Investigation (Washington, District of Columbia) |
| ASSIGNEE(S) | Federal Bureau of Investigation (Washington, District of Columbia) |
| INVENTOR(S) | Ian B. Vabnick (Fredericksburg, Virginia); Phillip R. Quillen (Huntsville, Alabama) |
| ABSTRACT | A press device having a cradle, a base plate, a fracturing device, an actuator, a switch, and a body. The base plate is located at a first end of the cradle. The fracturing device is proximally located at a second end of the cradle. The cradle is adapted to work in communication with the base plate to maintain alignment between the baseplate and the fracturing device. The actuator is proximally located to the second end of the cradle. The switch is operably connecting the actuator to the fracturing device. The body holds the cradle, base plate, fracturing device, actuator driven ram, and switch. The preferred embodiment uses a hydraulic ram. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109438 |
| CURRENT CPC | Presses in General B30B 1/007 (20130101) B30B 15/04 (20130101) B30B 15/065 (20130101) Blasting F42D 5/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20230258205 | Romo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Francisco X. Romo (Rockford, Illinois) |
| ABSTRACT | In accordance with at least one aspect of this disclosure, a system includes, a servo configured to control a position of a valve, a driver operatively connected to control movement of the servo, a control module operatively connected to control the driver, can configured to control the driver with pulse width modulated output to control a frequency of a generator through movement of the servo. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/670308 |
| CURRENT CPC | Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 13/0401 (20130101) F15B 21/087 (20130101) Original (OR) Class F15B 2013/0409 (20130101) F15B 2211/427 (20130101) F15B 2211/605 (20130101) F15B 2211/634 (20130101) F15B 2211/6656 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, August 17, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230817.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page