FedInvent™ Patent Applications
Application Details for Thursday, August 24, 2023
This page was updated on Thursday, August 24, 2023 at 03:58 PM GMT
Department of Health and Human Services (HHS)
| US 20230263232 | FUEMMELER et al. |
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| FUNDED BY |
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| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia); PENNINGTON BIOMEDICAL RESEARCH INSTITUTE (Baton Rouge, Louisiana); EAST CAROLINA UNIVERSITY (Greenville, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bernard FUEMMELER (Henrico, Virginia); Thomas EISSENBERG (Henrico, Virginia); Corby MARTIN (Baton Rouge, Louisiana); Eric SOULE (Greenville, North Carolina) |
| ABSTRACT | Provided are systems and methods of identifying the functional characteristics and operational settings of any electronic inhalants or apparatuses that are designed to provide nicotine vapors to a user. The system includes a mobile device having a built-in camera to receive images of a nicotine delivery device, a system of remote backend servers with at least one image database for identifying the nicotine delivery device, and at least one processor for calculating an amount of nicotine delivered by the nicotine delivery device. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 18/005624 |
| CURRENT CPC | Smokers\' Requisites; Match Boxes; Simulated Smoking Devices A24F 40/50 (20200101) Original (OR) Class A24F 40/60 (20200101) A24F 40/65 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263455 | CHIANG et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board Of Regents of The University of Texas System (Austin, Texas) |
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| INVENTOR(S) | Florence Yi Yi Ling CHIANG (San Antonio, Texas); Peter T. FOX (San Antonio, Texas); Rebecca S. Romero (San Antonio, Texas); Larry PRICE (San Antonio, Texas) |
| ABSTRACT | Provided here are non-invasive methods for evaluating functional connectivity patterns in localized brain regions of a patient involving application of a MS-specific functional meta-analytic connectivity model in resting-state functional magnetic resonance imaging (rsfMRI) data to provide patients with appropriate medical care in response to output from the model. |
| FILED | Saturday, May 29, 2021 |
| APPL NO | 18/000157 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/72 (20130101) A61B 5/4064 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263551 | Bankiewicz |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
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| INVENTOR(S) | Krystof S. Bankiewicz (Oakland, California) |
| ABSTRACT | The use of stepped cannulas, wherein a step structure creates a backstop to reduce backflow along the cannula body, is known for convection enhanced delivery of agents to the brain and other structures within an animal. Described herein are novel and improved stepped cannula designs wherein the length of the cannula segment between the step and the dispensing outlet is variable and can be controllably adjusted inside the patient during delivery. This advantageously allows the operator to place the cannula step at the optimal position and deliver agents at one or more positions within the target structure. |
| FILED | Wednesday, January 25, 2023 |
| APPL NO | 18/101455 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/12 (20130101) A61B 17/3421 (20130101) Original (OR) Class A61B 17/3478 (20130101) A61B 2017/00991 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/46 (20130101) A61M 5/158 (20130101) A61M 5/3286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263565 | Borsic |
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| FUNDED BY |
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| APPLICANT(S) | NE Scientific, LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | NE Scientific, LLC (Boston, Massachusetts) |
| INVENTOR(S) | Andrea Borsic (Torino, Italy) |
| ABSTRACT | A system for ablation treatment of tissues including at least one tissue ablation device, an ablation device controller communicatively connected to the at least one tissue ablation device, and an imaging component, wherein the imaging component is configured to capture a captured image that includes a representation of the tissue ablation device. The system further including an ablation device identification component configured to receive the captured image, generate a plurality of region proposals from the captured image, extract a plurality of feature vectors from the plurality of region proposals, determine a class for each region proposal of the plurality of region proposals, and determine the position and orientation of the tissue ablation device as a function of the classes for each region proposal. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/890839 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/1206 (20130101) Original (OR) Class A61B 18/1815 (20130101) A61B 34/25 (20160201) A61B 90/37 (20160201) A61B 2018/00577 (20130101) A61B 2018/1861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263627 | Kheradvar et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arash Kheradvar (Irvine, California); Daryl C. Nguyen (Irvine, California) |
| ABSTRACT | A growth-accommodating prosthetic valve system that can accommodate a patient's growth over time. The system features an expandable stent that can expand from a contracted configuration to an expanded configuration and leaflets attached to the scaffold that is sewn along a path such that the length of the path stays generally the same as the scaffold moves from the contracted configuration to the expanded configuration. |
| FILED | Thursday, April 27, 2023 |
| APPL NO | 18/308239 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2418 (20130101) Original (OR) Class A61F 2/2433 (20130101) A61F 2210/0057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263688 | Young et al. |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
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| INVENTOR(S) | Aaron Young (Atlanta, Georgia); Inseung Kang (Atlanta, Georgia); Dawit Lee (Atlanta, Georgia) |
| ABSTRACT | An exemplary embodiment of the present disclosure provides a knee exoskeleton comprising a first interface, a second interface, an actuator, and a controller. The first interface can be configured to interface with a portion of a leg of a user above a knee joint of the user. The second interface can be configured to interface with a portion of the leg of the user below the knee joint of the user. The actuator can be configured to generate a torque to cause a movement of at least one of the first and second interfaces. The controller can be configured to control the actuator to vary the magnitude of torque generated by the actuator. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 18/003927 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) Original (OR) Class A61H 2003/007 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1628 (20130101) A61H 2230/625 (20130101) A61H 2230/655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263729 | Scott et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan A. Scott (Northfield, Illinois); Guillermo A. Ameer (Chicago, Illinois); Jacqueline A. Burke (Chicago, Illinois); Sean D. Allen (Chicago, Illinois); Sijia Yi (Evanston, Illinois) |
| ABSTRACT | Provided herein are nanocarriers for delivery of immunosuppressive agents. In some embodiments, provided herein are nanocarriers comprising a core comprising a poly(ethylene glycol)-block-poly(propylene sulfide) copolymer and least one therapeutic agent. In some embodiments, the nanocarriers may further comprise a targeting ligand displayed on a surface of the nanocarrier. The at least one therapeutic agent may be an anti-inflammatory agent. The disclosed nanocarriers may be incorporated into pharmaceutical compositions for use in methods of treating an inflammatory condition or preventing transplantation rejection in a subject. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/177694 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1273 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/436 (20130101) A61K 31/593 (20130101) A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/543 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) A61P 41/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263741 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
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| INVENTOR(S) | Lily Yang (Atlanta, Georgia); Xiangxue Guo (Atlanta, Georgia); Hui Mao (Johns Creek, Georgia); Wei Chen (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to nanoparticles coated with fusion proteins comprising a domain that binds a cancer marker and a domain comprising a toxic polypeptide. In certain embodiments, the targeted cancer marker is urokinase plasminogen activator receptor (uPAR) insulin-like growth factor 1 receptor (IGF1R), EGFR, HER2, and/or other member of the ErbB family of receptors. In certain embodiments, the molecule that binds a cancer marker is an amino terminal fragment of uPA or variant capable of binding uPAR and/or IGF1 or variant capable of binding IGF1R. In certain embodiments, the toxic polypeptide is a bacterial exotoxin. |
| FILED | Monday, March 13, 2023 |
| APPL NO | 18/182682 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 47/6415 (20170801) Peptides C07K 14/65 (20130101) C07K 16/30 (20130101) C07K 16/2863 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263774 | HUARD et al. |
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| FUNDED BY |
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| APPLICANT(S) | Steadman Philippon Research Institute (Vail, Colorado) |
| ASSIGNEE(S) | Steadman Philippon Research Institute (Vail, Colorado) |
| INVENTOR(S) | Johnny HUARD (Edwards, Colorado); Marc Joseph PHILIPPON (Edwards, Colorado) |
| ABSTRACT | The present disclosure provides methods for enhancing a therapeutic outcome in a subject having a musculoskeletal condition or disorder, comprising administering at least one senolytic agent and/or at least one anti-fibrotic agent to the subject. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 18/040959 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) A61K 31/4178 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/00 (20180101) A61P 19/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263776 | Johnson |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bankole A. Johnson (Charlottesville, Virginia) |
| ABSTRACT | Compositions and methods are provided that are useful for diagnosing, treating, and monitoring alcohol dependence and disorders, susceptibility to alcohol dependence disorders, as well as drug related dependence and disorders. The methods include treating patients with an antagonist of the serotonin receptor 5-HT3 for such disorders, wherein the patient's serotonin transporter gene SLC6A4 is known to have particular genotypes. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/188755 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4178 (20130101) Original (OR) Class A61K 31/7048 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6888 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263783 | Yaffe et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael B. Yaffe (West Roxbury, Massachusetts); Brian A. Joughin (Cambridge, Massachusetts); Jesse C. Patterson (Natick, Massachusetts) |
| ABSTRACT | An effective amount of one or more microtubule polymerization inhibitors is administered in combination with one or more polo-like kinase (Plk) inhibitors for treating cancer. Administration of the combination of the active agents can be effective to reduce cancer cell proliferation or viability in a subject with cancer to the same degree, or a greater degree, than administering to the subject the same amount of either active agent alone. The active agents can be administered together or separately. Methods of selecting and treating subjects with cancers are also provided. |
| FILED | Tuesday, December 13, 2022 |
| APPL NO | 18/065348 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0056 (20130101) A61K 31/40 (20130101) A61K 31/437 (20130101) Original (OR) Class A61K 31/5025 (20130101) A61K 31/5365 (20130101) A61K 51/0463 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263797 | Deretic et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vojo P. Deretic (Placitas, New Mexico); Graham Timmins (Albuquerque, New Mexico); Suresh Kumar (Albuquerque, New Mexico) |
| ABSTRACT | The present invention is directed to elucidating the mechanism of formation of autophagosomal membranes that emerge via convergence of secretory and endosomal pathways and providing therapeutic approaches to the treatment of several acute respiratory syndrome coronavirus 1 (SARS) and 2 SARS-CoV-2), MERS-CoV and numerous other autophagy-mediated diseases based upon this mechanism. This process is targeted by microbial factors such as coronaviral membrane modulating proteins and represents a potential target for agents which may be used in the treatment of SARS, COVID and MERS. The present invention is also directed to compositions and methods for the treatment of SARS, COVID and/or MERS and other autophagy-mediated disease states. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895849 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/03 (20130101) A61K 31/135 (20130101) A61K 31/495 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263800 | Dudakov et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| INVENTOR(S) | Jarrod Dudakov (Seattle, Washington); Sinead Kinsella (Seattle, Washington); Lorenzo Iovino (Seattle, Washington) |
| ABSTRACT | Compositions and methods to promote thymic function are described. The compositions and methods can activate the GPR39 receptor and/or a purinergic receptor, such as P2Y2. The activation can upregulate regenerative molecules, such as FOXN1, interleukin (IL)-22, IL-23, and bone morphogenetic protein 4 (BMP4). |
| FILED | Wednesday, November 03, 2021 |
| APPL NO | 18/043303 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/351 (20130101) A61K 31/365 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/675 (20130101) A61K 31/4184 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263817 | Tian et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Rong Tian (Seattle, Washington); Dennis Ding-Hwa Wang (Seattle, Washington); Bo Zhou (Seattle, Washington); Kevin Douglas O'Brien (Seattle, Washington) |
| ABSTRACT | The current disclosure provides use of high dose nicotinamide adenine dinucleotide (NAD) precursor regimens for reduction of inflammation in human patients with preexisting inflammation. The NAD precursor can be nicotinamide riboside (NR) and the high dose regimen can include at least 1000 or 2000 mg/day for at least 9 days. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 18/024032 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/706 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5094 (20130101) G01N 33/6869 (20130101) G01N 2333/545 (20130101) G01N 2333/5412 (20130101) G01N 2800/325 (20130101) G01N 2800/7095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263829 | Honkanen et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Alabama Foundation for Research and Commercialization (Mobile, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Eric Honkanen (Mobile, Alabama); Brandon Marshall D'Arcy (Mobile, Alabama); Mark Raymond Swingle (Mobile, Alabama) |
| ABSTRACT | Compositions, methods, and systems for modifying sterol metabolism in a subject is disclosed. In some embodiments, the subjects may be administered one or more mammalian cells modified to express at least one sterol degrading enzyme derived from a bacterium. In many embodiments, the cell is a macrophage or monocyte stably expressing three or more enzymes that aid in opening the β ring of cholesterol. The disclosed compositions and methods may be useful in lowering cholesterol levels in a subject in need thereof. In some embodiments, the subject may have a genetic predisposition to atherosclerosis. |
| FILED | Wednesday, March 01, 2023 |
| APPL NO | 18/115846 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 2319/43 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/001 (20130101) C12N 15/52 (20130101) C12N 15/62 (20130101) C12N 2710/16141 (20130101) C12N 2820/005 (20130101) C12N 2820/60 (20130101) Enzymes C12Y 101/01051 (20130101) C12Y 101/01145 (20130101) C12Y 103/01021 (20130101) C12Y 103/99004 (20130101) C12Y 106/02004 (20130101) C12Y 114/15 (20130101) C12Y 114/15006 (20130101) C12Y 118/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263831 | Hill et al. |
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| FUNDED BY |
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| APPLICANT(S) | FRED HUTCHINSON CANCER CENTER (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER CENTER (Seattle, Washington) |
| INVENTOR(S) | Geoffrey Hill (Seattle, Washington); Simone Minnie (Seattle, Washington) |
| ABSTRACT | Methods for treating malignancies including multiple myeloma (MM), methods for expanding immune cells, methods for characterizing and enhancing anti-tumor functions of immune cells, and methods for characterizing immune cell responses to agonist immunotherapies including decoy-resistant IL-18 (DR-18) therapies. The methods include administering a composition to enrich for a precursor exhausted population with stem-like properties and the ability for self-renewal (TPEX cells), which is crucial for sustaining an immune response to chronic infection and tumors TPEX cells and/or TOX+TEFF cells |
| FILED | Thursday, February 23, 2023 |
| APPL NO | 18/173485 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/20 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263832 | Park et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Shin-Young Park (Waltham, Massachusetts); Leslie E. Silberstein (Miami, Florida); Jina Ryu (Seoul, South Korea); Min Liu (Brighton, Massachusetts) |
| ABSTRACT | Provided herein, in some aspects, are compositions comprising vasoocclusion-inhibiting agents encapsulated in RBCs and uses thereof for treating blood vessel occlusion (e.g., in Sickle Cell Disease). |
| FILED | Friday, July 09, 2021 |
| APPL NO | 18/015209 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/4439 (20130101) A61K 31/4709 (20130101) A61K 35/18 (20130101) Original (OR) Class A61K 38/58 (20130101) A61K 38/482 (20130101) A61K 39/3955 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) Enzymes C12Y 304/21068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263855 | Wickline et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida); Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samuel A. Wickline (Temple Terrace, Florida); Hua Pan (Tampa, Florida); Christine Thien-Nga Pham (St. Louis, Missouri); Huimin Yan (St. Louis, Missouri) |
| ABSTRACT | The present disclosure relates to nanoparticles and methods for polynucleotide transfection. |
| FILED | Friday, November 18, 2022 |
| APPL NO | 18/056823 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 31/7105 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 47/64 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 19/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263861 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer Yunyan Zhang (Durham, North Carolina); Jessica Shannon (Durham, North Carolina) |
| ABSTRACT | Provided herein are methods for promoting hair growth in a subject involving providing TSLP to the subject. Further provided herein are methods for preventing hair loss in a subject, including chemotherapy-induced hair loss, by inhibiting TSLP in the subject. |
| FILED | Thursday, February 23, 2023 |
| APPL NO | 18/173358 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) A61K 38/20 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263872 | Pineda et al. |
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| FUNDED BY |
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| APPLICANT(S) | Envisagenics, Inc. (New York, New York) |
| ASSIGNEE(S) | Envisagenics, Inc. (New York, New York); Envisagenics, Inc. (New York, New York) |
| INVENTOR(S) | Maria Luisa Pineda (New York, New York); Martin Akerman (Huntington, New York); Gayatri Arun (Huntington Station, New York); Naomi Yudanin (New York, New York); Priyanka Dhingra (Jersey City, New Jersey) |
| ABSTRACT | Provided herein are systems and methods for identifying alternative splicing derived cell surface antigens. Also provided are methods and compositions for using the identified cell surface antigens. Further provided are methods, compositions, and systems for diagnosing diseases in a subject using the identified cell surface antigens or treating diseases using the same. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 18/023674 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/4611 (20230501) A61K 39/4631 (20230501) A61K 39/4632 (20230501) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4748 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/00 (20190201) G16B 40/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263875 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Szu-Wen Wang (Irvine, California); Nicholas Molino (Philadelphia, Pennsylvania); Medea Neek (Irvine, California); Edward L. Nelson (Irvine, California); Jo Anne Tucker (Irvine, California) |
| ABSTRACT | Cancer-testis antigens were simultaneously packaged with CpG adjuvant and incorporated into an E2 nanoparticle platform to increase cancer vaccine efficacy. Also described herein is a combination of checkpoint blockade therapy and the nanoparticle vaccine platform to deliver cancer antigens with adjuvant for treatment of tumors and prevention of future tumors. The nanoparticle vaccine platform includes a protein capsule to which are attached adjuvants in the internal hollow cavity and cancer epitopes to the surface. Whereas single-therapies only increase survival, the combined therapy can both increase survival time as well as prevent tumor development in pre-existing tumor conditions by increasing tumor antigen-specific responses (via the nanoparticle vaccines) while simultaneously blocking checkpoints to remove immune suppression (via immune checkpoint inhibition). Furthermore, tumor rechallenge studies show evidence of T cell memory which can prevent tumor development in some individuals. |
| FILED | Friday, September 23, 2022 |
| APPL NO | 17/934996 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/001154 (20180801) A61K 39/001184 (20180801) Original (OR) Class A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263883 | Elledge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women`s Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen J. Elledge (Brookline, Massachusetts); Ellen Shrock (Boston, Massachusetts); Eric Fujimura (Boston, Massachusetts) |
| ABSTRACT | Peptide epitopes identified in subjects infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and methods of use thereof for diagnosing, determining prognosis, and treating Coronavirus Disease 2019 (COVID-19), and developing prophylactic or therapeutic vaccines against SARS-CoV-2. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 18/014947 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Original (OR) Class A61K 49/0004 (20130101) Peptides C07K 16/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263890 | Myo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tessa Therapeutics Ltd. (Singapore, Singapore); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | Tessa Therapeutics Ltd. (Singapore, Singapore); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Aung Myo (Singapore, Singapore); Ivan David Horak (Singapore, Singapore); Jonathan Serody (Chapel Hill, North Carolina); Gianpietro Dotti (Chapel Hill, North Carolina); Barbara Savoldo (Chapel Hill, North Carolina) |
| ABSTRACT | Methods for treating a CD30-positive cancer in a subject are disclosed, wherein the methods comprise administering a lymphodepleting chemotherapy and CD30-specific chimeric antigen receptor (CAR)-expressing cells. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 18/007709 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) A61K 31/7076 (20130101) A61K 39/4611 (20230501) A61K 39/4622 (20230501) A61K 39/4631 (20230501) A61K 39/464411 (20230501) A61K 39/464417 (20230501) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 2317/53 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263891 | CHALASANI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Sreekanth CHALASANI (La Jolla, California); Yusuf TUFAIL (La Jolla, California); Jose Mendoza LOPEZ (La Jolla, California); Marc Duque RAMIREZ (La Jolla, California); Uri MAGARAM (La Jolla, California); Corinne LEE-KUBLI (La Jolla, California); Eric Warren EDSINGER (La Jolla, California) |
| ABSTRACT | Described herein are compositions featuring TRPA1 polypeptides and polynucleotides, methods for expressing such polypeptides and polynucleotides in a cell type of interest, and methods for inducing the activation of the TRPA1 polypeptide in neurons and other cell types using ultrasound. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 18/016251 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) A61K 41/0028 (20130101) Original (OR) Class A61K 48/0083 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263943 | Myung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States Government as represented by the Department of Veterans Affairs (NW Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Myung (Saratoga, California); Fang Chen (Stanford, California); Gabriella Fernandes-Cunha (Palo Alto, California); Sarah Hull (Stanford, California); Sarah Heilshorn (Mountain View, California); Christopher Lindsay (San Mateo, California); Christopher Madl (Los Altos, California); Hyun Jong Lee (Gyeonggi-do, South Korea) |
| ABSTRACT | Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined hydrogel structure in situ, including interpenetrating (IPN) and semi-IPN hydrogels. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/997097 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/142 (20130101) A61F 2210/0085 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 2400/06 (20130101) A61L 2430/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264043 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Xiaodong Wu (Iowa City, Iowa); Weiyu Xu (Iowa City, Iowa); Jirong Yi (Iowa City, Iowa) |
| ABSTRACT | A method for needle position optimization for prostate brachytherapy for use with a radiation delivery device configured to use a plurality of needles inserted into a prostate of a patient includes obtaining imagery of the prostate of the patient, generating a needle pool for prostate brachytherapy treatment of the patient based on the imagery of the prostate of the patient, and determining at a computing device an optimum prostate brachytherapy treatment plan for the patient by iteratively removing needles from the needle pool by forming and computationally solving a convex optimization problem wherein the convex optimization problem uses a quadratic dosimetric penalty function, dwell time regularization by total variation, and block sparsity regularization term. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/170784 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1014 (20130101) Original (OR) Class A61N 5/1039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265068 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Tennessee Research Foundation (Memphis, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Memphis, Tennessee) |
| INVENTOR(S) | Wei Li (Germantown, Tennessee); Julio Cordero-Morales (Germantown, Tennessee); Jianxiong Jiang (Memphis, Tennessee); Zhongzhi Wu (Collierville, Tennessee); Francesca Liao (Memphis, Tennessee); Catherine Kaczorowski (Memphis, Tennessee) |
| ABSTRACT | Provided herein are compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat diseases or disorders associated with TRPC3 activity. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299562 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) Heterocyclic Compounds C07D 401/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265070 | Buhrlage et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sara Buhrlage (Somerville, Massachusetts); Kenneth C. Anderson (Wellesley, Massachusetts); Dharminder Chauhan (Natick, Massachusetts); Sirano Dhe-Paganon (Holliston, Massachusetts); Xiaoxi Liu (Burlington, Massachusetts); Hyuk-Soo Seo (Boston, Massachusetts) |
| ABSTRACT | The present disclosure relates to inhibitors of USP7 useful in the treatment of cancers, and other USP7 mediated diseases, having the Formula: wherein R1, R2, R3, R4, R5, R6, and n are described herein. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/902512 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/06 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 403/06 (20130101) C07D 413/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265149 | VEISEH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Omid VEISEH (Houston, Texas); David ZHANG (Houston, Texas); Sudip MUKHERJEE (Houston, Texas); Maria RUOCCO (Houston, Texas); Michael DOERFERT (Houston, Texas); Amanda NASH (Houston, Texas); Samira AGHLARA-FOTOVAT (Houston, Texas) |
| ABSTRACT | The present disclosure relates to implantable constructs (encapsulated cells) designed to deliver antigenic therapeutic reagents, such as IL-2. |
| FILED | Wednesday, October 19, 2022 |
| APPL NO | 18/047856 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/55 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) C12N 5/0621 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265165 | JIN |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Moonsoo JIN (New York, New York) |
| ABSTRACT | The present invention is directed to transduced T cells expressing at least 100,000 molecules of human somatostatin receptor 2 (SSTR2), which improves PET/CT imaging sensitivity. The present invention is also directed to transduced T cells expressing SSTR2 and chimeric antigen receptor (CAR). In one embodiment, the CAR is specific to human ICAM-1 and the CAR comprises a binding domain that is scFv of anti-human ICAM-1, or an I domain of the αL subunit of human lymphocyte function-associated antigen-1. In another embodiment, the CAR is specific to human CD19, and the CAR comprises a binding domain that is scFv of anti-human CD19. The present invention is further directed to using the above transduced T cells for monitoring T cell distribution in a patient by PET/CT imaging and/or treating cancer. |
| FILED | Tuesday, March 21, 2023 |
| APPL NO | 18/187268 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/1796 (20130101) A61K 39/0011 (20130101) A61K 39/001166 (20180801) A61K 51/083 (20130101) A61K 51/088 (20130101) A61K 2039/54 (20130101) A61K 2039/515 (20130101) Peptides C07K 14/723 (20130101) Original (OR) Class C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70553 (20130101) C07K 2319/03 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265169 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Korea (Center for Disease Control and Prevention) (Chungcheongbuk-do, South Korea) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hansaem Lee (Chungcheongbuk-do, South Korea); Janghoon Choi (Chungcheongbuk-do, South Korea); Sungsoon Kim (Chungcheongbuk-do, South Korea); Lingshu Wang (Bethesda, Maryland); Barney Graham (Bethesda, Maryland); John R Mascola (Bethesda, Maryland) |
| ABSTRACT | The present invention relates to monoclonal antibodies for a spike protein of the Middle East respiratory syndrome coronavirus (MERS-CoV), and a use thereof. Particularly, monoclonal antibodies 77-A5, 77-A6, 90-A3, 90-A9, 90-B2, 90-B7, 90-C4, 90-E5, 90-E6, 90-F1 and 90-F2 according to the present invention have excellent attachment force with respect to a full-length spike protein of MERS-CoV and the S1 domain of the protein, and, of the monoclonal antibodies, the monoclonal antibodies 90-F1, 90-E5, 90-E6, 90-F2, 77-A5 and 77-A6 have excellent attachment force with respect to an RBD antigen of MERS-CoV. Also, the antibodies 77-A5, 77-A6, 90-E5, 90-E6, 90-F1 and 90-F2 exhibit neutralizing capacity with respect to a MERS pseudovirus and MERS-CoV, and the antibodies 90-B2 and 90-B7 exhibit neutralizing capacity only with respect to MERS-CoV. Further, the monoclonal antibodies have a particular monomeric form, and have excellent stability and thus may be useful for treating or diagnosing MERS. |
| FILED | Sunday, September 25, 2022 |
| APPL NO | 17/952308 |
| CURRENT CPC | Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265180 | GREENE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark I. GREENE (Penn Valley, Pennsylvania); Zheng CAI (Wynnewood, Pennsylvania); Zhiqiang ZHU (Philadelphia, Pennsylvania); Douglas B. CINES (Wynnewood, Pennsylvania) |
| ABSTRACT | Provided herein are isolated antibodies or antibody fragments thereof that immunospecifically bind to platelet factor 4 (PF4). In some embodiments the isolated antibodies or antigen-binding fragments thereof comprise a light chain CDR and framework region comprising SEQ ID NO: 4 and a heavy chain CDR and framework region comprising SEQ ID NO: 10. Also provided herein are methods for treating heparin-induced thrombocytopenia (HIT) and methods for reducing the likelihood that subject will become afflicted with HIT. Further disclosed are uses of the isolated antibodies or antibody fragments in the treatment of HIT or the manufacture of compositions for the treatment of HIT. |
| FILED | Tuesday, November 29, 2022 |
| APPL NO | 18/071057 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/702 (20130101) A61K 31/727 (20130101) A61K 38/00 (20130101) Peptides C07K 16/24 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265206 | WELLS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | James A. WELLS (San Francisco, California); Alexander J. MARTINKO (San Francisco, California); Juan E. DIAZ (San Francisco, California); Michael J. HORNSBY (San Francisco, California) |
| ABSTRACT | The disclosure is related to antibodies and antibody fragments that specifically bind the CUB domain-containing protein 1 (CDCP1) and their methods and uses in treating and detecting cancers. |
| FILED | Friday, March 10, 2023 |
| APPL NO | 18/182277 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6803 (20170801) A61K 47/6849 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2809 (20130101) C07K 16/2896 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/70596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265214 | Quijano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut); GENNAO BIO, INC. (Pennington, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elias Quijano (New Haven, Connecticut); Peter Glazer (New Haven, Connecticut); Bruce C. Turner (Bryn Mawr, Pennsylvania); Audrey Turchick (Chelmsford, Massachusetts); W. Mark Saltzman (New Haven, Connecticut) |
| ABSTRACT | Compositions and methods of use thereof for delivering nucleic acid cargo into cells are provided. The compositions typically include (a) a 3E10 monoclonal antibody or an antigen binding, cell-penetrating fragment thereof; a monovalent, divalent, or multivalent single chain variable fragment (scFv); or a diabody; or humanized form or variant thereof, and (b) a nucleic acid cargo including, for example, a nucleic acid encoding a polypeptide, a functional nucleic acid, a nucleic acid encoding a functional nucleic acid, or a combination thereof. Elements (a) and (b) are typically non-covalently linked to form a complex. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 18/043534 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/40 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/117 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265382 | Young, JR. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samuel M. Young, JR. (Iowa City, Iowa); Stacia Phillips (Iowa City, Iowa) |
| ABSTRACT | Methods to produce helper dependent adenovirus, and a cell, vector and kit useful in that regard, are provided. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984575 |
| CURRENT CPC | Peptides C07K 14/075 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2710/10041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265383 | Wilson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wilson Wolf Manufacturing (New Brighton, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John R. Wilson (New Brighton, Minnesota) |
| ABSTRACT | This invention relates to methods and devices that improve cell culture efficiency. They include the use of gas permeable culture compartments that reduce the use of space while maintaining uniform culture conditions, and are more suitable for automated liquid handling. They include the integration of gas permeable materials into the traditional multiple shelf format to resolve the problem of non-uniform culture conditions. They include culture devices that use surfaces comprised of gas permeable, plasma charged silicone and can integrate traditional attachment surfaces, such as those comprised of traditional tissue culture treated polystyrene. They include culture devices that integrate gas permeable, liquid permeable membranes. A variety of benefits accrue, including more optimal culture conditions during scale up and more efficient use of inventory space, incubator space, and disposal space. Furthermore, labor and contamination risk are reduced. |
| FILED | Friday, April 07, 2023 |
| APPL NO | 18/132235 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/08 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265387 | Gros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Alena Gros (Barcelona, Spain); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Methods of obtaining a cell population enriched for tumor-reactive T cells, the method comprising: (a) obtaining a bulk population of T cells from a tumor sample; (b) specifically selecting CD8+ T cells that express any one or more of TIM-3, LAG-3, 4-1BB, and PD-1 from the bulk population; and (c) separating the cells selected in (b) from unselected cells to obtain a cell population enriched for tumor-reactive T cells are disclosed. Related methods of administering a cell population enriched for tumor-reactive T cells to a mammal, methods of obtaining a pharmaceutical composition comprising a cell population enriched for tumor-reactive T cells, and isolated or purified cell populations are also disclosed. |
| FILED | Friday, January 06, 2023 |
| APPL NO | 18/093902 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 5/0638 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265393 | SABAAWY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, the State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hatim SABAAWY (Neshanic Station, New Jersey); Fredrick E. WONDISFORD (New Brunswick, New Jersey) |
| ABSTRACT | Liver metabolism studies are limited by the inability to expand primary hepatocytes in vitro while maintaining their metabolic functions. Human hepatic three dimensional organoids have been established for use in these studies, but hepatic organoids from adult donors had impaired expansion. Methods of achieving expansion of adult donor-derived hepatic organoids (HepAOs) and HepG2 cells (HepGOs) from single cells in organoid cultures using combinations of growth factors and small molecules are described, with assessment of expansion dynamics, gluconeogenic and HNF4α expression, and albumin secretion. The invention discloses conditions including limiting A8301 and incorporating FSK and OSM to allow the expansion of HepAOs from adult donors and HepGOs with gluconeogenic competence. These models increase the repertoire of human hepatic cellular tools available for use in liver metabolic assays. |
| FILED | Monday, September 26, 2022 |
| APPL NO | 17/935135 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0671 (20130101) Original (OR) Class C12N 2500/30 (20130101) C12N 2500/90 (20130101) C12N 2501/155 (20130101) C12N 2501/237 (20130101) C12N 2501/727 (20130101) C12N 2506/14 (20130101) C12N 2506/30 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265405 | CHAUHAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | VIKASH PAL SINGH CHAUHAN (CAMBRIDGE, Massachusetts); PHILLIP A. SHARP (NEWTON, Massachusetts); ROBERT LANGER (NEWTON, Massachusetts) |
| ABSTRACT | The present disclosure provides a method of editing a genome in a cell including exposing the cell to an engineered Cas nuclease comprising one or more mutations within the DNA binding cleft of the Cas nuclease, wherein exposure to the engineered Cas nuclease decreases, inhibits, or prevents non-homologous end joining (NHEJ) in the cell, and wherein exposure to the engineered Cas nuclease increases one or more homology-driven repair pathways within the cell. The mutant Cas nuclease is also disclosed herein. |
| FILED | Wednesday, December 21, 2022 |
| APPL NO | 18/069387 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265420 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Jonathan Strecker (Cambridge, Massachusetts); Alim Ladha (Cambridge, Massachusetts); Guilhem Faure (Cambridge, Massachusetts) |
| ABSTRACT | The present application provides systems, methods and compositions used for targeted gene modification, targeted insertion, perturbation of gene transcripts, nucleic acid editing. Novel nucleic acid targeting systems comprise components of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems and transposable elements. |
| FILED | Friday, June 18, 2021 |
| APPL NO | 17/928355 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/90 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265422 | Farzan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (, None) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Farzan (Juno Beach, Florida); Guocai Zhong (Jupiter, Florida); Haiming Wang (Jupiter, Florida) |
| ABSTRACT | The present invention provides novel RNA switches that are based on modified hammerhead ribozymes with improved activities. Also provided are expression vectors and related expression systems for regulating transgene expression in various clinical or industrial applications. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/768896 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/635 (20130101) C12N 2310/121 (20130101) C12N 2310/128 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265425 | GARG |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Angad GARG (New York, New York) |
| ABSTRACT | The present disclosure provides gene expression systems and methods for producing and/or overexpressing heterologous polypeptides in eukaryotic cells. Kits for practicing the methods are also disclosed. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 18/004028 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/81 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2320/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265432 | RONAI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ze'ev A. RONAI (Fallbrook, California); Ali KHATEB (San Diego, California) |
| ABSTRACT | The present disclosure provides compositions and methods for treating acute myeloid leukemia (AML) using a histone deacetylase (HDAC) inhibitor alone or incombination with a RING finger protein 5 (RNF5) inhibitor and/or a retinoblastoma binding protein 4 (RBBP4) inhibitor. Moreover, RNF5 and/or RBBP4 expression or protein levels in a patient can be measured and used to inform individualized treatment options and dosing regiments. For example, AML patients with lower levels of either RNF5 or RBBP4 may be stratified and treated with one or more HDAC inhibitors leading to improved therapeutic results. |
| FILED | Thursday, October 20, 2022 |
| APPL NO | 18/048382 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 31/167 (20130101) A61K 31/365 (20130101) A61K 31/427 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4178 (20130101) A61K 31/7072 (20130101) A61K 38/15 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Original (OR) Class C12N 2310/531 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57426 (20130101) G01N 2440/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265440 | Gomez-Ospina et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Natalia Gomez-Ospina (Stanford, California); Matthew H. Porteus (Stanford, California); Samantha Glynne Scharenberg (Stanford, California); Alvaro Amorin (Stanford, California) |
| ABSTRACT | The present disclosure provides methods and compositions for treating lysosomal storage disorders in subjects, comprising genetically modifying cells from the subjects ex vivo by integrating therapeutic transgenes into the CCR5 locus. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 18/010773 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 9/24 (20130101) C12N 15/86 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/321 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 302/01076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265442 | Djuranovic et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sergej Djuranovic (St. Louis, Missouri); Rachel Green (Baltimore, Maryland) |
| ABSTRACT | The present disclosure relates to modulation of protein expression. |
| FILED | Monday, March 13, 2023 |
| APPL NO | 18/182948 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/64 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265453 | Xue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mingshan Xue (Houston, Texas); Wu Chen (Houston, Texas) |
| ABSTRACT | The disclosure concerns compositions and methods for treatment of encephalopathies, including encephalopathies caused by, or associated with, and STXBP1 haploinsufficiency or mutation. Compositions and methods provided herein encompass AAV particles that induce expression of STXBP1, including inducing the expression of STXBP1 in central and/or peripheral nervous system cells. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 18/004194 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265455 | Boye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Shannon E. Boye (Gainesville, Florida); Sanford L. Boye (Gainesville, Florida) |
| ABSTRACT | The present disclosure provides for improved recombinant AAV therapies for the treatment of X-linked retinoschisis (XLRS). These therapies are designed for administration to subjects, such as human subjects, including humans diagnosed with or suffering from XLRS. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 18/017726 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 48/0058 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Peptides C07K 14/005 (20130101) C07K 14/47 (20130101) C07K 14/475 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265487 | Seelig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (Seattle, Washington); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/188504 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265508 | Vizcardo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Raul E. Vizcardo (Foster City, California); SM Rafiqul Islam (Bethesda, Maryland); Naritaka Tamaoki (South San Francisco, California); Takuya Maeda (Bethesda, Maryland); Nicholas P. Restifo (Chevy Chase, Maryland) |
| ABSTRACT | Disclosed are methods for reprogramming cancer-reactive T cells into iPSC cells as well as methods utilizing such cells for the identification of cancer-antigen specific TCRs and the treatment of cancer. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 18/020823 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) C12N 2501/51 (20130101) C12N 2501/515 (20130101) C12N 2502/30 (20130101) C12N 2506/11 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265516 | GARCIA et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF ARIZONA, ARIZONA BOARD OF REGENTS (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joe G.N. GARCIA (Tucson, Arizona); Mohamed n. AHMED (Tucson, Arizona) |
| ABSTRACT | A method of identifying single nucleotide polymorphisms (SNPs) within the NAMPT promoter that are associated with an inflammatory condition, such as cardiac ischemia, traumatic brain injury, cancer, chorioamnionitis, nonalcoholic steatohepatitis (NASH), or renal fibrosis. Also provided are methods of diagnosing and treating such inflammatory condition in a subject. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 18/040976 |
| CURRENT CPC | Peptides C07K 16/40 (20130101) C07K 2317/565 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266211 | D'SILVA et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph D'SILVA (Hillsboro, Oregon); Robert H. AUSTIN (Princeton, New Jersey); Curt CIVIN (Baltimore, Maryland); James C. STURM (Princeton, New Jersey) |
| ABSTRACT | Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 17/948541 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) A61K 35/28 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/1894 (20130101) B01L 2400/086 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class G01N 15/1404 (20130101) G01N 33/5094 (20130101) G01N 2015/008 (20130101) G01N 2333/70596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266214 | COON et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Joshua COON (Middleton, Wisconsin); Michael WESTPHALL (Fitchburg, Wisconsin) |
| ABSTRACT | The present invention provides methods for controllably forming a layer of amorphous ice and other amorphous solids on a substrate, and also provides cryo-electron microscopy (cryo-EM) sample preparation methods and systems that utilize in vacuo formation of amorphous ice and other solids. Formation of the amorphous solid layer can be independent of the deposition of sample molecules to be analyzed using electron microscopy, and allows for the generation of a uniformly thick layer. Optionally, mass spectrometry instruments are used to generate and purify molecules deposited on the generated amorphous solid layer. The techniques and systems described herein can deliver near ideal cryo-EM sample preparation to greatly increase resolution, sensitivity, scope, and throughput of cryo-EM protein imaging, and therefore greatly impact the field of structural biology. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984934 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/36 (20130101) G01N 1/42 (20130101) Original (OR) Class G01N 15/1468 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/26 (20130101) H01J 37/28 (20130101) H01J 49/164 (20130101) H01J 49/165 (20130101) H01J 2237/31745 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266270 | GURKAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | UMUT GURKAN (Shaker Heights, Ohio); MICHAEL HINCZEWSKI (Cleveland, Ohio); SHAMREEN IRAM (Cleveland, Ohio); RAN AN (Shaker Heights, Ohio) |
| ABSTRACT | An example system includes one or more non-transitory machine-readable media and one or more processors. The non-transitory machine-readable media is configured to store data and instructions, in which the data includes image data having a plurality of image frames of an electrophoresis process performed on a sample over a time interval. The sample contains at least one analyte. The one or more processors are configured to access the data and execute the instructions, in which the instructions programmed to perform a method. The method can include determining values of pixels within a region of interest (ROI) of respective image frames in the time interval. The method can also include analyzing the determined pixel values for at least some of the respective image frames. The method can also include estimating a quantity of the at least one analyte in the sample based on the analysis of the pixel values. |
| FILED | Monday, June 28, 2021 |
| APPL NO | 18/012951 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44721 (20130101) Original (OR) Class G01N 33/721 (20130101) G01N 33/726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266304 | SCHULTZ-CHERRY et al. |
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| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stacey SCHULTZ-CHERRY (Memphis, Tennessee); Victoria MELIOPOULOS (Memphis, Tennessee); Rebekah HONCE (Memphis, Tennessee) |
| ABSTRACT | A method for establishing an obese ferret model by feeding a ferret with a diet having at least 25% of carbohydrate content for a period of time to provide the obese ferret model is disclosed as is a method of using said model to screen a substance for treating a respiratory infection. |
| FILED | Monday, July 12, 2021 |
| APPL NO | 18/005105 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5088 (20130101) Original (OR) Class G01N 2333/11 (20130101) G01N 2333/46 (20130101) G01N 2333/165 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266306 | Kumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland) |
| ASSIGNEE(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland) |
| INVENTOR(S) | Sanjai Kumar (Potomac, Maryland); Nitin Verma (Germantown, Maryland); Ankit Puri (Rockville, Maryland) |
| ABSTRACT | Identification of immunodominant Babesia microti antigens using genome-wide immunoscreening is described. Candidate antigens were screened against sera from patients with clinical babesiosis. Also described are diagnostic assays with high sensitivity and specificity for detecting B. microti-specific antibodies in patient samples using the identified immunodominant antigens. |
| FILED | Tuesday, March 21, 2023 |
| APPL NO | 18/187241 |
| CURRENT CPC | Peptides C07K 14/44 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1096 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54306 (20130101) Original (OR) Class G01N 33/56905 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266315 | James et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
| ASSIGNEE(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma); Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
| INVENTOR(S) | Judith A. James (Oklahoma City, Oklahoma); Melissa E. Munroe (Oklahoma City, Oklahoma) |
| ABSTRACT | The present invention involves the identification of biomarkers that are predictive of impeding systemic lupus erythematosus (SLE) disease flare. Methods for treating patients so identified are also provided. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/946756 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) Original (OR) Class G01N 33/6863 (20130101) G01N 2800/52 (20130101) G01N 2800/104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266321 | Dar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arvin Dar (New York, New York); Zaigham M. Khan (New York, New York); William Michael Marsiglia (New York, New York) |
| ABSTRACT | A detectable probe comprising a moiety, which is an ATP non-competitive inhibitor of mitogen-activated protein kinase (MEK), inter alia, human MEK (MEK1 or MEK2) having the properties: (i) allosterically binds an inhibitor pocket formed at an interaction interface between human MEK (MEK1 or MEK2) and human Kinase Suppressor of Ras (KSR1 or KSR2 orBRAF) adjacent to ATP in a physiological complex between MEK and KSR (or BRAF), forming an inhibitor-inhibitor pocket complex; (ii) is an ATP non-competitive kinase inhibitor; (iii) a structure such that when bound to the inhibitor-inhibitor pocket complex, the complex comprises the structural elements: (a) at least one moiety of the inhibitor engaging A825 of KSR1, or P878 of KSR2; or R662 of BRAF (b) at least one moiety engaging R234 of MEK, wherein where R234 is within 5 A from any atoms of KSR1 or KSR2 or BRAF is disclosed. The probe further comprises a detectable label conjugated directly or through a linker to the inhibitor moiety. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 18/002812 |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/573 (20130101) Original (OR) Class G01N 33/5011 (20130101) G01N 2333/912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266329 | LYDEN et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David C. LYDEN (Old Chatham, New York); Haiying ZHANG (New York, New York) |
| ABSTRACT | The present invention is directed to methods of diagnosing, prognosing, and managing treatment of cancer in a subject. These methods involve selecting a subject having cancer and obtaining, from the selected subject, a population of either exomeres having a diameter less than 50 nm, small exosomes having a diameter of 60-80 nm, or large exosomes having a diameter of 90-120 nm. The exomeres, small exosomes, or large exosomes are recovered from the sample, and the exomeres, small exosomes, or large exosomes or portions thereof are contacted with one or more reagents suitable to detect: (1) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more proteins contained in said exomeres, small exosomes, or large exosomes, (2) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more N-glycans contained in said exomeres, small exosomes, or large exosomes, (3) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more lipids contained in said exomeres, small exosomes, or large exosomes, (4) the presence or absence of one or more genetic mutations in nucleic acid molecules associated with cancer and contained in said exomeres, small exosomes, or large exosomes, or (5) combinations thereof. Cancer is then diagnosed, prognosed, or treatment is modified based on this information. |
| FILED | Thursday, December 15, 2022 |
| APPL NO | 18/082368 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/6893 (20130101) G01N 33/57484 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266334 | Mitra |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robi D. Mitra (Fenton, Missouri) |
| ABSTRACT | Methods are disclosed for identifying one or more proteins or polypeptides comprised by a sample. The methods comprise determining binding of each polypeptide with respect to each binding pool of a plurality of binding pools, wherein each binding pool comprises one or more probes which bind a structure comprised by a protein or polypeptide. In some aspects, polypeptides can be denatured and separated into individual polypeptide strands and immobilized on a solid support prior to determining binding of the binding pools. A protein, polypeptide or polypeptide strand can be identified by searching, in at least one database, for a protein or polypeptide sequence comprising binding pool targets either identical to or most similar to the binding pool targets comprised by the protein, polypeptide or polypeptide strand to be identified. Kits for identifying proteins, polypeptides and polypeptide strands are also disclosed. |
| FILED | Monday, May 01, 2023 |
| APPL NO | 18/141767 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/6845 (20130101) Original (OR) Class G01N 33/54306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266417 | Zhong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zheng Zhong (Houston, Texas); Christopher Michael Sandino (Menlo Park, California); Shreyas S. Vasanawala (Stanford, California) |
| ABSTRACT | A method for magnetic resonance imaging (MRI) performs a spoiled gradient-recalled (SPGR) MRI scan with an MRI scanner to produce MRI data; and reconstructs an MRI image from the MRI data; wherein performing the SPGR MRI scan comprises playing an interleaved-randomized spoiler (IRS) gradient after every M-th acquisition block, where M≥2, and where an absolute area of the IRS gradient of each IRS is randomized between zero and a maximum gradient area achievable on the MRI scanner. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/113805 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/561 (20130101) Original (OR) Class G01R 33/5608 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266418 | Kulam Najmudeen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Magdoom Mohamed Kulam Najmudeen (Bethesda, Maryland); Peter J. Basser (Bethesda, Maryland); Michal E. Komlosh (Bethesda, Maryland) |
| ABSTRACT | Diffusion sensitizing gradient pulse pairs are prescribed in a manner to mitigate effects of concomitant gradient artifacts. Measured MR signals generated by applying a plurality of diffusion sensitizing gradient matrices are obtained and processed to determine a second order mean diffusion tensor and a fourth order covariance tensor. Quantities derived from these tensors are measured and mapped within an imaging volume which describe features of diffusion anisotropy and heterogeneity within each imaging voxel. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 18/017150 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/022 (20130101) G01R 33/246 (20130101) G01R 33/56341 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266577 | CUI |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Meng CUI (West Lafayette, Indiana) |
| ABSTRACT | High speed laser scanning systems and methods are disclosed for imaging target samples. Embodiments of the laser scanning systems and methods include separating a laser beam into two or more different pathways and pulsing light along the two or more pathways. The different pathways intersect the surface of a moving mirror at different locations and light traveling in a pathway that is being approached by an edge of the moving reflective surface is turned off while light traveling in a different pathway that is farther from the edge of the moving reflective surface is turned on. Embodiments include reflective surfaces that form a rotating polygonal scanner. Further embodiments include recombining the two or more different pathways, focusing the laser light on a test sample, and imaging the light reflected from the test sample. |
| FILED | Tuesday, February 21, 2023 |
| APPL NO | 18/172139 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0048 (20130101) Original (OR) Class G02B 26/124 (20130101) G02B 26/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267607 | Sadri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amir Reza Sadri (Cleveland Heights, Ohio); Satish E. Viswanath (Beachwood, Ohio); Thomas Desilvio (Lyndhurst, Ohio) |
| ABSTRACT | In some embodiments, the present disclosure relates to a non-transitory computer-readable medium storing computer-executable instructions that, when executed, cause a processor to perform operations, including forming an imaging dataset having imaging data corresponding to one or more radiological images of a patient having a bowel disease; operating upon the imaging data with one or more convolutional neural network (CNN) segments configured to generate a plurality of CNN outputs, the one or more CNN segments respectively including a convolution layer configured to perform a convolution on the imaging data; and applying a wavelet network to the plurality of CNN outputs to generate a plurality of convolution wavelet network (CWN) outputs, the wavelet network being configured to decompose the plurality of CNN outputs according to a mother wavelet. A predictive signature associated with disease response or risk is constructed using the plurality of CWN outputs. |
| FILED | Thursday, February 16, 2023 |
| APPL NO | 18/169935 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10116 (20130101) G06T 2207/20064 (20130101) G06T 2207/20084 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268029 | Flusberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin Flusberg (Atlanta, Georgia); Jonas Korlach (Camas, Washington); Andrey Kislyuk (San Ramon, California); Stephen Turner (Seattle, Washington); Jon Sorenson (Alameda, California); Kevin Travers (Menlo Park, California); Cheryl Heiner (La Honda, California); Austin B. Tomaney (Burlingame, California); Patrick Marks (San Francisco, California); Dale Webster (San Mateo, California); Jeremiah Hanes (Menlo Park, California) |
| ABSTRACT | Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/189075 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/32 (20130101) A61F 2/30721 (20130101) Original (OR) Class A61F 2/30767 (20130101) A61F 2/30965 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268030 | Flusberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin Flusberg (Atlanta, Georgia); Jonas Korlach (Camas, Washington); Andrey Kislyuk (San Ramon, California); Stephen Turner (Seattle, Washington); Jon Sorenson (Alameda, California); Kevin Travers (Menlo Park, California); Cheryl Heiner (La Honda, California); Austin B. Tomaney (Burlingame, California); Patrick Marks (San Francisco, California); Dale Webster (San Mateo, California); Jeremiah Hanes (Menlo Park, California) |
| ABSTRACT | Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/189084 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/32 (20130101) A61F 2/30721 (20130101) Original (OR) Class A61F 2/30767 (20130101) A61F 2/30965 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268170 | LI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peng LI (Morgantown, West Virginia); Xiaojun LI (Morgantown, West Virginia); Stephen J. VALENTINE (Morgantown, West Virginia); Lisa HOLLAND (Morgantown, West Virginia) |
| ABSTRACT | In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to a vibrating sharp edge spray ionization (VSSI) method suitable for coupling with a mass spectrometer, a VSSI method modified with a capillary suitable for use with continuous-flow separation methods such as liquid chromatography, and a VSSI method suitable for coupling with a capillary electrophoresis (CE) device in order to introduce the CE sample flow into a mass spectrometer. Also disclosed herein are devices for carrying out these methods and methods of making the same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Wednesday, February 22, 2023 |
| APPL NO | 18/172780 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/16 (20130101) Original (OR) Class H01J 49/0031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230263164 | Bowden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Ned B. Bowden (Iowa City, Iowa); Justin M. CARTER (Iowa City, Iowa); Eric M. BROWN (Iowa City, Iowa); Nimesh RANASINGHE (Iowa City, Iowa); Arjun PAUDEL (Iowa City, Iowa); Erin E. IRISH (Iowa City, Iowa) |
| ABSTRACT | The invention provides a compound of formula (I): wherein X, Y Z, R1, R2, and X+ have any of the values described in the specification. The compounds are useful to increase plant growth and/or to increase harvest yield. |
| FILED | Monday, August 30, 2021 |
| APPL NO | 18/024034 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 57/12 (20130101) Original (OR) Class A01N 57/16 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 21/00 (20210801) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/06 (20130101) C07F 9/6578 (20130101) C07F 9/657118 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263688 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aaron Young (Atlanta, Georgia); Inseung Kang (Atlanta, Georgia); Dawit Lee (Atlanta, Georgia) |
| ABSTRACT | An exemplary embodiment of the present disclosure provides a knee exoskeleton comprising a first interface, a second interface, an actuator, and a controller. The first interface can be configured to interface with a portion of a leg of a user above a knee joint of the user. The second interface can be configured to interface with a portion of the leg of the user below the knee joint of the user. The actuator can be configured to generate a torque to cause a movement of at least one of the first and second interfaces. The controller can be configured to control the actuator to vary the magnitude of torque generated by the actuator. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 18/003927 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) Original (OR) Class A61H 2003/007 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1628 (20130101) A61H 2230/625 (20130101) A61H 2230/655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263729 | Scott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan A. Scott (Northfield, Illinois); Guillermo A. Ameer (Chicago, Illinois); Jacqueline A. Burke (Chicago, Illinois); Sean D. Allen (Chicago, Illinois); Sijia Yi (Evanston, Illinois) |
| ABSTRACT | Provided herein are nanocarriers for delivery of immunosuppressive agents. In some embodiments, provided herein are nanocarriers comprising a core comprising a poly(ethylene glycol)-block-poly(propylene sulfide) copolymer and least one therapeutic agent. In some embodiments, the nanocarriers may further comprise a targeting ligand displayed on a surface of the nanocarrier. The at least one therapeutic agent may be an anti-inflammatory agent. The disclosed nanocarriers may be incorporated into pharmaceutical compositions for use in methods of treating an inflammatory condition or preventing transplantation rejection in a subject. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/177694 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1273 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/436 (20130101) A61K 31/593 (20130101) A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/543 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) A61P 41/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263918 | Whitten et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David G. Whitten (Albuquerque, New Mexico); Kirk S. Schanze (Gainesville, Florida); Linnea K. Ista (Albuquerque, New Mexico); Patrick L. Donabedian (Gainesville, Florida); Eva Yung Hua Chi (Albuquerque, New Mexico); Florencia A. Monge (Albuquerque, New Mexico); Alison Meredith Kell (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David G. Whitten (Albuquerque, New Mexico); Kirk S. Schanze (Gainesville, Florida); Linnea K. Ista (Albuquerque, New Mexico); Patrick L. Donabedian (Gainesville, Florida); Eva Yung Hua Chi (Albuquerque, New Mexico); Florencia A. Monge (Albuquerque, New Mexico); Alison Meredith Kell (Albuquerque, New Mexico) |
| ABSTRACT | A method of inactivating an enveloped ssRNA virus, such as SARS-CoV-2. The method involves contacting the enveloped ssRNA virus with an antiviral polyelectrolyte compound and/or a conjugated aromatic compound effective to inactivate the virus. The disclosure also provides a method of reducing the period of viability of enveloped ssRNA virus, such as SARS-CoV-2, on personal protective equipment, in filtered air, and on surfaces that have come into contact with the virus. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 18/017813 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/18 (20130101) A61L 2/084 (20130101) A61L 2/088 (20130101) Original (OR) Class A61L 2101/38 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264114 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts); Soleeva Energy, Inc. (San Jose, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yi Zheng (Canton, Massachusetts); Ralph Ahlgren (San Jose, California); Xiaojie Liu (Boston, Massachusetts); Yanpei Tian (Boston, Massachusetts); Mohamed Sonbaty (San Jose, California); Khushnood Ahmad Qazi (Los Altos, California) |
| ABSTRACT | A floatable interfacial solar-driven evaporation structure includes a water impervious thermal insulation layer adapted to float on a body of water, a porous absorber layer on the water impervious thermal insulation layer, and an interlocked non-woven cotton fiber layer having a portion thereof between the water impervious insulation layer and the porous absorber layer and one or more additional portions configured to extend to the body of water to act as a capillary-driven pump to transport water from the body of water to the porous absorber layer. An ultra-black photothermal paint covers the exposed upper surface of the porous absorber layer to convert solar radiation impinging on the ultra-black photothermal paint into heat for use in generating water vapor from water in the porous absorber layer. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 18/041130 |
| CURRENT CPC | Separation B01D 1/22 (20130101) B01D 1/0035 (20130101) Original (OR) Class B01D 5/0066 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/08 (20130101) C02F 1/14 (20130101) C02F 2103/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264970 | KUNO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Masaru KUNO (South Bend, Indiana); Michael BRENNAN (South Bend, Indiana); Anthony RUTH (South Bend, Indiana); Ilia PAVLOVETC (South Bend, Indiana); Jeffrey A. CHRISTIANS (Golden, Colorado); Taylor Hennessey MOOT (Golden, Colorado); Joseph Matthew LUTHER (Golden, Colorado) |
| ABSTRACT | Compositions comprise a perovskite and a non-perovskite. Perovskites comprise AxA′yA″(1−x−y)BX3, and non-perovskites may comprise A″, B and X, where A is a first cation, A′ is a second cation, A″ is a third cation, B is a fourth cation, X is an anion. In some instances, A, A′, and A″ are each independently (NH2)2CH+, CH3NH3+, Cs+, Rb+, or (NH2)2(C═NH2)+, with the proviso that A, A′, and A″ are each different. The perovskite may have a first crystal structure in which the anion is corner-sharing, the non-perovskite may have a second crystal structure comprising at least one of an orthorhombic structure, a hexagonal structure, or a perovskite-like structure, and 1−x−y may be greater than about 0.15. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 18/003776 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/005 (20130101) B05D 3/007 (20130101) B05D 2601/28 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/16 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) Organic electric solid-state devices H10K 30/10 (20230201) H10K 30/50 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264983 | Meegoda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| INVENTOR(S) | Jay Meegoda (Orange, New Jersey); Jitendra Kewalramani (Iselin, New Jersey) |
| ABSTRACT | A treatment method and system using high-frequency ultrasound for treating a waste stream containing per- and polyfluoroalkyl substance (PFAS) is disclosed. The system has one or more reactors including one or more transducers configured to operating at one or more frequencies to destroy or mineralize the per- and polyfluoroalkyl substances (PFAS) in the waste stream using sonolysis. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 18/024423 |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0607 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/36 (20130101) Original (OR) Class C02F 1/68 (20130101) C02F 2101/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265377 | Sniadecki et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Nathan J. Sniadecki (Seattle, Washington); Ty Higashi (Seattle, Washington); Daniel Moskowitz (Seattle, Washington); Jevne Micheau-Cunningham (Seattle, Washington); Robert Bruce Darling (Seattle, Washington) |
| ABSTRACT | Devices and methods configured to determine characteristics of tissue specimens are provided. Representative tissue analysis devices include a sensing module and a reference module. The sensing module includes a first post and a second post configured to have the tissue specimen affixed thereto, and a displacement sensor configured to output a displacement signal corresponding to a displacement of the first post. The reference module includes a reference sensor configured to output a reference signal corresponding to a reference input such as an ambient magnetic field. The devices further include instructions that determine: a displacement value based upon the displacement signal; a reference value based upon the reference signal; a reference-canceled displacement value based upon the displacement value and the reference value; and a characteristic of the tissue specimen based upon the reference-canceled displacement value. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/766876 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/12 (20130101) C12M 35/04 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265447 | Voytas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel F. Voytas (Falcon Heights, Minnesota); Ryan A. Nasti (Berkeley, California); Michael F. Maher (St. Paul, Minnesota) |
| ABSTRACT | Materials and methods for inducing genetic alterations in meristematic plant tissue are provided herein. |
| FILED | Friday, March 03, 2023 |
| APPL NO | 18/178290 |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 4/008 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8213 (20130101) C12N 15/8229 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265477 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University Of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig Martin (Amherst, Massachusetts); Elvan Cavac (Northampton, Massachusetts); Kithmie Harshana Malagodapathiranage (Amherst, Massachusetts); Shuo Sui (Sunderland, Massachusetts); Sarah L. Perry (Belchertown, Massachusetts); Yasaman Gholamalipour (Worcester, Massachusetts) |
| ABSTRACT | Described herein are synthetic methods for producing sequence-specific RNA oligonucleotides that eliminate impurities produced in prior art methods. In one aspect, an end-protected capture DNA complementary to a portion of the product RNA is employed. In another aspect, the template DNA is covalently or noncovalently linked to the RNA polymerase, either directly or through the use of a nontemplate DNA. In a third aspect, a flow chamber is employed. All of the methods can be used in combination. |
| FILED | Tuesday, January 10, 2023 |
| APPL NO | 18/152367 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1247 (20130101) C12N 15/10 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6865 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265487 | Seelig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (Seattle, Washington); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/188504 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265571 | Hugar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ecolectro, Inc (lthaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kristina Hugar (Ithaca, New York); Gabriel Rodriguez-Calero (Willseyville, New York); Sarah Nathan (Wilmington, Delaware); Sarah Louise Poole (Syracuse, New York) |
| ABSTRACT | The present disclosure relates to composite materials comprising a reinforcement material and a cationic polyelectrolyte, such as a porous reinforcement material impregnated with the cationic poly electrolyte. The present disclosure further relates to membrane electrode assemblies comprising the composites of the disclosure, and electrochemical devices comprising the disclosed membrane electrode assemblies. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 18/020473 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/23 (20210101) C25B 13/07 (20210101) C25B 13/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265572 | Kuhl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Twelve Benefit Corporation (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kendra Kuhl (Oakland, California); Etosha Cave (Berkeley, California); Nicholas Flanders (San Francisco, California); Sichao Ma (Dublin, California); Qun Zeng (Oakland, California); George Leonard (Oakland, California) |
| ABSTRACT | A system preferably including a carbon dioxide reactor. A method for carbon dioxide reactor control, preferably including selecting carbon dioxide reactor aspects based on a desired output composition, running a carbon dioxide reactor under controlled process conditions to produce a desired output composition, and/or altering the process conditions to alter the output composition. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 18/051944 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/02 (20130101) C25B 9/23 (20210101) C25B 9/70 (20210101) C25B 11/031 (20210101) C25B 15/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266943 | Seok et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mingoo Seok (Tenafly, New Jersey); Dewei Wang (New York, New York); Chuan-Tung Lin (New York, New York) |
| ABSTRACT | Various embodiments described herein provide for a digital In-Memory Computing (IMC) macro circuit that utilizes approximate arithmetic hardware to reduce the number of transistors and devices in the circuit relative to a convention digital IMC, thereby improving the area-efficiency of the digital IMC, but while retaining the benefits of reduced variability relative to an analog-mixed-signal (AMS) circuit. The proposed digital IMC macro circuit also includes custom full adder (FA) circuits with pass gate logic in a ripple carry adder (RCA) tree. The disclosed digital IMC macro circuit can also perform a vector-matrix dot product in one cycle while achieving high energy and area efficiency. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/110152 |
| CURRENT CPC | Electric Digital Data Processing G06F 7/501 (20130101) G06F 7/5312 (20130101) G06F 7/5443 (20130101) Original (OR) Class Pulse Technique H03K 19/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266972 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Timothy Glenn Rogers (West Lafayette, Indiana); Mahmoud Khairy (West Lafayette, Indiana) |
| ABSTRACT | A system may include a central processing unit (CPU) having a Simultaneous Multi-Threading (SMT) thread/execution model. The system may further include a request processing unit (RPU) having an Out-of-Order Single Instruction Multiple Thread (SIMT) execution model. The CPU may receive a plurality of requests. The CPU may group a portion of the requests in a batch. The CPU may cause the RPU to execute instructions corresponding to each request in the batch. The RPU may execute, with a plurality of threads, the instructions corresponding to the batch of requests in lockstep. |
| FILED | Wednesday, November 30, 2022 |
| APPL NO | 18/072492 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3842 (20130101) G06F 9/3851 (20130101) Original (OR) Class G06F 9/4881 (20130101) G06F 9/30087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267284 | Garg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Divyansh Garg (Stanford, California); Skanda Vaidyanath (Stanford, California) |
| ABSTRACT | Systems and methods for automated response to natural language instructions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for training an agent, the method including sampling an instruction and observation pair from a dataset, predicting a skill code, using a skill predictor, based on the instruction and observation pair, predicting, for each of a plurality of timesteps, a set of one or more actions based on the predicted skill code and a state history using a policy, and updating the skill predictor and the policy based on a comparison of the predicted set of actions and the observation. In many embodiments, the trained agent can then be used to carry out natural language instructions. |
| FILED | Wednesday, February 22, 2023 |
| APPL NO | 18/172969 |
| CURRENT CPC | Electric Digital Data Processing G06F 40/44 (20200101) G06F 40/55 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267324 | Seif Tabrizi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Seyed Alireza Seif Tabrizi (Adelphi, Maryland); Changhun Oh (Chicago, Illinois); Tao Hong (San Jose, California); Liang Jiang (Chicago, Illinois) |
| ABSTRACT | A machine learning method for model-free inference of target physical parameters from a metrology dataset is generally disclosed. The disclosed method is particularly applied to atomic interferometry for sensing/measuring physical quantities such as acceleration and rotations from measured atomic interference patterns. The method operates without a need for an exact measurement-dependent mathematical/analytical model and without a need for explicit knowledge of instrumental error processes that affect the measurement. The disclosed method is based on neural networks that are trained or calibrated to learn to simultaneously estimate the target physical quantities of interest and their measurement uncertainties. It extends the applicability of a metrology when instrumental precision is limited, and noise and imperfections are present. |
| FILED | Friday, December 23, 2022 |
| APPL NO | 18/088252 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230267361 — Controlled Photon Fock State Generation Using Arbitrarily Weak Photonic Nonlinearities
| US 20230267361 | Clerk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Aashish Clerk (Chicago, Illinois); Andrew Lingenfelter (Chicago, Illinois) |
| ABSTRACT | A method and system that harnesses extremely weak Kerr-type nonlinearities in a single driven cavity to deterministically generate single photon Fock states, and more general photon-blockaded states are disclosed. The disclosed scheme is effective even for nonlinearities that are much smaller than photonic loss in the cavity. The disclosed scheme generates photon-blockade states that are non-Gaussian, exhibit a sharp cut-off in their photon number distribution, and can be arbitrarily close to, for example, a single-photon Fock state. This scheme relies only standard linear and parametric drives, and are hence compatible with a variety of different photonic platforms. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/161569 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267369 | KALIVAS et al. |
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| FUNDED BY |
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| APPLICANT(S) | IDAHO STATE UNIVERSITY (Pocatello, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | JOHN KALIVAS (POCATELLO, Idaho); ROBERT SPIERS (BOISE, Idaho) |
| ABSTRACT | Methodologies and corresponding systems for a Local adaptive fusion regression (LAFR) process are able to search a large library of spectral measurement for a linear calibration (training) set, which is spectrally matrix matched to a target sample spectrum, and also tightly bracketed about an “unknown” prediction property (analyte) for the target sample. Using a matched calibration set, the likelihood of an accurate prediction by the selected calibration set is greatly enhanced. The LAFR process integrates multiple spectral similarity information with contextual considerations between source analyte contents, model, and analyte predictions. LAFR facilitates onsite chemical analysis such as with a handheld spectrometer, dedicated in-line process analyzers and benchtop instruments. LAFR is based on a Beer’s law like linear relationship where a calibration model (mathematical relationship) is made that linearly relates the analyte amount, e.g., concentration, to the measured spectral responses. The calibration model is then used to predict (quantitate) the analyte amounts present in new samples. |
| FILED | Wednesday, November 30, 2022 |
| APPL NO | 18/072090 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267720 | MARVASTI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ehsan Emad MARVASTI (Orlando, Florida); Arash RAFTARI (Orlando, Florida); Yaser Pourmohammadi FALLAH (Oviedo, Florida) |
| ABSTRACT | Situational awareness as a necessity in connected and autonomous vehicles domain is a subject of significant research in recent years. The driver’s safety is directly dependent on robustness, reliability and scalability of such systems. Cooperative mechanisms have provided a solution to improve situational awareness by utilizing communication networks. These mechanisms mitigate problems such as occlusion and sensor range limitation. However, the network capacity is a factor determining the maximum amount of information being shared among cooperative entities. A focus of this work is to reduce the network capacity requirements while maintaining the desirable object detection performance by utilizing and modifying the concept of feature sharing. Described here is a mechanism to further improve object detection performance by utilizing novel decentralized parallel frameworks and anew shared data alignment method to allow parallel and cooperative processing of sensed data in multiple locations yielding significant improvements in object detection. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/928473 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 2207/10028 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30252 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) Original (OR) Class G06V 20/56 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268170 | LI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peng LI (Morgantown, West Virginia); Xiaojun LI (Morgantown, West Virginia); Stephen J. VALENTINE (Morgantown, West Virginia); Lisa HOLLAND (Morgantown, West Virginia) |
| ABSTRACT | In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to a vibrating sharp edge spray ionization (VSSI) method suitable for coupling with a mass spectrometer, a VSSI method modified with a capillary suitable for use with continuous-flow separation methods such as liquid chromatography, and a VSSI method suitable for coupling with a capillary electrophoresis (CE) device in order to introduce the CE sample flow into a mass spectrometer. Also disclosed herein are devices for carrying out these methods and methods of making the same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Wednesday, February 22, 2023 |
| APPL NO | 18/172780 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/16 (20130101) Original (OR) Class H01J 49/0031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268483 | Ellison et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher John Ellison (Eden Prairie, Minnesota); Charles Buddie Mullins (West Lake Hills, Texas); Samantha Nicole Lauro (Austin, Texas); Joshua Paul Pender (Glendale, Wisconsin); Han Xiao (Minneapolis, Minnesota); Jason Alexander Weeks, JR. (Austin, Texas); James Norman Burrow, JR. (Austin, Texas) |
| ABSTRACT | A method of making a porous film includes disposing a slurry on a substrate, solidifying the slurry to yield a film on the substrate, and subliming the organic sublimable material to yield the porous film on the substrate. The slurry includes an electrochemically active material, an electrically conductive material, and a binder dispersed in an organic sublimable material. The electrochemically active material and the electrically conductive material are different. A slurry includes a solid component including an electrochemically active material, an electrically conductive material, and a binder; and a liquid component including an organic sublimable material, wherein the electrochemically active material and the electrically conductive material are different, and the solid component is dispersed in the liquid component. |
| FILED | Tuesday, February 21, 2023 |
| APPL NO | 18/112130 |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/18 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/366 (20130101) H01M 4/0404 (20130101) H01M 4/0433 (20130101) H01M 4/0485 (20130101) H01M 4/485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/622 (20130101) H01M 4/623 (20130101) H01M 4/1391 (20130101) Original (OR) Class H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268721 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma); Sandia National Laboratories (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rui Q. Yang (Norman, Oklahoma); John F. Klem (Albuquerque, New Mexico) |
| ABSTRACT | An ICL comprises: a plurality of IC stages, wherein each of the IC stages comprises: a hole injector; an electron injector; an active region coupled to the hole injector and the electron injector and comprising a first layer, wherein the first layer comprises a first material, and wherein the first material comprises InAsP or AlInAsP; a conduction band running through the hole injector, the electron injector, and the active region; and a valence band running through the hole injector, the electron injector, and the active region. |
| FILED | Monday, February 13, 2023 |
| APPL NO | 18/168337 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/3402 (20130101) Original (OR) Class H01S 5/3422 (20130101) H01S 5/34306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268945 | Peroulis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dimitrios Peroulis (West Lafayette, Indiana); Mohammad Abu Khater (West Lafayette, Indiana) |
| ABSTRACT | Systems and methods for wideband RF interference detection and suppression include an open-circuit stub, a first voltage peak detector, a second voltage peak detector, an analog-to-digital converter (ADC), and a controller. The open-circuit stub is configured to receive an input signal. The first voltage peak detector is coupled at the open end of the open-circuit stub and configured to output a first voltage signal based on a portion of the input signal. The second voltage peak detector is coupled a distance away from the open end of the open-circuit stub and configured to output a second voltage signal based on the portion of the input signal. The controller is configured to generate an output control signal operable to adjust a signal filter based on the first digital voltage signal and the second digital voltage signal to suppress the portion of the input signal. |
| FILED | Wednesday, February 22, 2023 |
| APPL NO | 18/112604 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/04 (20130101) Transmission H04B 1/1027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230269202 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jun Xu (Atlanta, Georgia); Long Gong (Atlanta, Georgia); Jingfan Meng (Atlanta, Georgia) |
| ABSTRACT | An exemplary sliding window scheduling method and system are disclosed. The exemplary sliding window scheduling method and system can schedule multiple packets in a given scheduling frame with a sliding window scheduling frame. The scheduling operation can be performed using bitmap operators and can achieve a lowest time complexity of O(1) per matching computation and per port using distributed parallelization hardware. The exemplary sliding window scheduling method and system can be performed in the context of a queue-proportional scheduler (QPS) as well as iSLIP. In alternative embodiments, the SW-QPS operation can be performed in a batching window rather than in a sliding window. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 18/020822 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/28 (20130101) H04L 47/225 (20130101) H04L 49/3027 (20130101) H04L 49/3045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230269377 | Kodukula et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Venkatesh Kodukula (Tempe, Arizona); Alexander Shearer (Tempe, Arizona); Van Nguyen (Madison, Wisconsin); Srinivas Lingutla (Chicago, Illinois); Robert LiKamWa (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Venkatesh Kodukula (Tempe, Arizona); Alexander Shearer (Tempe, Arizona); Van Nguyen (Madison, Wisconsin); Srinivas Lingutla (Chicago, Illinois); Robert LiKamWa (Tempe, Arizona) |
| ABSTRACT | A system defining a visual sensing pipeline architecture flexibly allows application developers to dynamically adapt the spatial resolution and update rate of different “rhythmic pixel encoding regions” in a scene. The system ingests pixel streams with raster-scan pixel read-out patterns, but only encodes relevant pixels prior to storing them in memory. The system includes streaming hardware to decode the stored rhythmic pixel encoding region stream into traditional frame-based representations to feed into standard computer vision algorithms. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/174259 |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 19/33 (20141101) H04N 19/132 (20141101) Original (OR) Class H04N 19/167 (20141101) H04N 19/172 (20141101) H04N 19/182 (20141101) H04N 19/423 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230263392 | Cascales Sandoval et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Juan Pedro Cascales Sandoval (Somerville, Massachusetts); Conor L. Evans (Charlestown, Massachusetts) |
| ABSTRACT | A sensor system includes a probe, and a photon source configured to direct photons at the probe. The probe can emit light in response to receiving photons. The sensor system can include a photodetector configured to detect the light emitted from the probe, and a configured to cause the photon source to emit photons according to a first time-varying intensity profile having a first frequency. The controller can be configured to receive optical data from the photodetector based on the interaction between the light emitted from the probe and the photodetector. The optical data can include a second time-varying intensity profile having a second frequency. The second frequency can be substantially the same as the first frequency. The controller can be configured to determine a difference in phase between the first time-varying intensity profile and the second time-varying intensity profile, and generate a report based on the difference in phase. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 18/043659 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0008 (20130101) Original (OR) Class A61B 2562/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263932 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Embody, Inc. (Norfolk, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert S. Brown (Norfolk, Virginia); Caitlin Harclerode (Norfolk, Virginia); Nardos Sori (Norfolk, Virginia); Michael P. Francis (Norfolk, Virginia); Nicholas Thayer (Morrisville, North Carolina) |
| ABSTRACT | An implantable biopolymer scaffold includes at least one braided strand comprising high strength collagen fibers and synthetic fibers, wherein the collagen fibers have a greater cross-sectional deform ability than the synthetic fibers. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/167051 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 17/08 (20130101) A61L 17/14 (20130101) Original (OR) Class A61L 17/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264006 | Kamen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dean Kamen (Bedford, New Hampshire); Lee A. Batchelder (Auburn, New Hampshire); Eitan C. Zeira (Hollis, New Hampshire); Linda R. Rios Guevara (Manchester, New Hampshire); Joshua A. Frye (Manchester, New Hampshire); Hans E. Johnson (Salem, New Hampshire) |
| ABSTRACT | A delivery device for delivery of medical agent to a barrier may comprise a main body including a central region defining a receptacle, a peripheral region defined by a number of petal members, and a set of retention tabs extending into the receptacle. The delivery device may further comprise a reservoir including at least one delivery sharp, a main interior volume, and at least one septum in fluid communication with the main interior volume. The reservoir may be coupled to the main body via the retention tabs. The delivery device may further comprise an adhesive coupled to the main body. The delivery device may further comprise at least one bias member positioned within the receptacle between the reservoir and a wall of the receptacle. |
| FILED | Thursday, December 22, 2022 |
| APPL NO | 18/087058 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264148 | Boettcher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Shannon Boettcher (Eugene, Oregon); Lihaokun Chen (Eugene, Oregon); James Mitchell (Eugene, Oregon); Sayantan Sasmal (Eugene, Oregon); Nicole Sagui (Eugene, Oregon); Prasad Sarma (Eugene, Oregon) |
| ABSTRACT | A bipolar membrane comprising a first member comprising at least one anion exchange material; a second member comprising at least one cation exchange material, wherein the first member and the second member together form an interface junction; and disposed within the interface junction a solitary layer comprising a composite water dissociation catalyst or a composite water recombination catalyst. |
| FILED | Wednesday, February 22, 2023 |
| APPL NO | 18/112868 |
| CURRENT CPC | Separation B01D 61/445 (20130101) Original (OR) Class B01D 69/02 (20130101) B01D 2325/10 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/052 (20210101) C25B 11/077 (20210101) C25B 11/091 (20210101) C25B 13/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264358 | Blankespoor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOSTON DYNAMICS, INC. (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Blankespoor (Arlington, Massachusetts); Benjamin Stephens (Somerville, Massachusetts); Marco da Silva (Arlington, Massachusetts) |
| ABSTRACT | An example method may include i) detecting a disturbance to a gait of a robot, where the gait includes a swing state and a step down state, the swing state including a target swing trajectory for a foot of the robot, and where the target swing trajectory includes a beginning and an end; and ii) based on the detected disturbance, causing the foot of the robot to enter the step down state before the foot reaches the end of the target swing trajectory. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299645 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/16 (20130101) B25J 9/1628 (20130101) B25J 9/1679 (20130101) B25J 9/1692 (20130101) Original (OR) Class Motor Vehicles; Trailers B62D 57/032 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) Y10S 901/46 (20130101) Y10S 901/49 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264972 | Hennighausen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Zachariah B. Hennighausen (Newton, Massachusetts); Bethany Hudak (Accokeek, Maryland); Olaf M.J. van 't Erve (Falls Church, Virginia); Madeleine Phillips (Alexandria, Virginia) |
| ABSTRACT | A nano-thin BixOySez low-temperature oxygen transporter membrane for oxygen transport, separation, and two-dimensional (2D) material manipulation comprising a material comprising a compound of BixOySez and R |
| FILED | Thursday, February 23, 2023 |
| APPL NO | 18/113285 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 29/00 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2002/20 (20130101) C01P 2002/82 (20130101) C01P 2004/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265311 | Pojman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John Anthony Pojman (Baton Rouge, Louisiana); Daniel Paul Gary (Sulphur, Louisiana) |
| ASSIGNEE(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | John Anthony Pojman (Baton Rouge, Louisiana); Daniel Paul Gary (Sulphur, Louisiana) |
| ABSTRACT | The present invention relates to a resin composition comprising 20-70 wt % of an aromatic di(meth)acrylate component; 5-25 wt % of a flexible di(meth)acrylate component; and 10-70 wt % of a crosslinker component; wherein the resin composition further comprises: 0.1-10 phr initiator; 0-10 phr silica; and 5-50 phr milled carbon fiber. The invention also relates to a polymerized coating disposed over a substrate, the coating comprising 20-70 wt % aromatic di(meth)acrylate subunits; 5-25 wt % flexible di(meth)acrylate subunits; and 10-70 wt % crosslinker subunits; wherein the coating further comprises: 0.1-10 phr silica; and 5-50 phr milled carbon fiber. The invention also relates to a method of depositing a coating over a substrate, the method comprising the steps of: providing a resin composition; applying the resin composition over a substrate; and polymerizing the resin composition to form a solid coating. |
| FILED | Wednesday, November 23, 2022 |
| APPL NO | 18/058352 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/108 (20130101) B05D 3/0254 (20130101) B05D 7/14 (20130101) B05D 2202/15 (20130101) B05D 2502/00 (20130101) B05D 2601/22 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/36 (20130101) C08K 5/14 (20130101) Compositions of Macromolecular Compounds C08L 33/10 (20130101) C08L 2312/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/61 (20180101) C09D 7/63 (20180101) C09D 133/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265387 | Gros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Alena Gros (Barcelona, Spain); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Methods of obtaining a cell population enriched for tumor-reactive T cells, the method comprising: (a) obtaining a bulk population of T cells from a tumor sample; (b) specifically selecting CD8+ T cells that express any one or more of TIM-3, LAG-3, 4-1BB, and PD-1 from the bulk population; and (c) separating the cells selected in (b) from unselected cells to obtain a cell population enriched for tumor-reactive T cells are disclosed. Related methods of administering a cell population enriched for tumor-reactive T cells to a mammal, methods of obtaining a pharmaceutical composition comprising a cell population enriched for tumor-reactive T cells, and isolated or purified cell populations are also disclosed. |
| FILED | Friday, January 06, 2023 |
| APPL NO | 18/093902 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 5/0638 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266197 | Posada |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Natalia Posada (Dayton, Ohio) |
| ABSTRACT | A portable tracer fluid injection system. The system has a vapor cloud generator which vaporizes a vapor cloud generating liquid. The vapor cloud generator is uses a sub-ohm resistive heater to vaporize small volumes of the vapor cloud generating liquid, allowing for a relatively small tracer fluid injection system. This system has the benefit of being able to target specific regions of a test object within a wind tunnel and being usable for different positions within the test section of a wind tunnel. |
| FILED | Monday, April 10, 2023 |
| APPL NO | 18/297674 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 9/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266274 | Giurgiutiu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Victor Giurgiutiu (Columbia, South Carolina); Jingjing Bao (West Columbia, South Carolina); Banibrata Poddar (Germantown, Maryland); Md Yeasin Bhuiyan (West Columbia, South Carolina) |
| ABSTRACT | The current disclosure determines if structural faults exist and extracts geometric features of the structural faults from acoustic emission waveforms, such as crack length and orientation, and can evaluate the structural faults online, during normal operation conditions. |
| FILED | Tuesday, April 11, 2023 |
| APPL NO | 18/298508 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/14 (20130101) Original (OR) Class G01N 29/46 (20130101) G01N 29/2437 (20130101) G01N 29/4454 (20130101) G01N 2291/0231 (20130101) G01N 2291/0232 (20130101) G01N 2291/0258 (20130101) G01N 2291/0289 (20130101) G01N 2291/2634 (20130101) G01N 2291/2693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266329 | LYDEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David C. LYDEN (Old Chatham, New York); Haiying ZHANG (New York, New York) |
| ABSTRACT | The present invention is directed to methods of diagnosing, prognosing, and managing treatment of cancer in a subject. These methods involve selecting a subject having cancer and obtaining, from the selected subject, a population of either exomeres having a diameter less than 50 nm, small exosomes having a diameter of 60-80 nm, or large exosomes having a diameter of 90-120 nm. The exomeres, small exosomes, or large exosomes are recovered from the sample, and the exomeres, small exosomes, or large exosomes or portions thereof are contacted with one or more reagents suitable to detect: (1) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more proteins contained in said exomeres, small exosomes, or large exosomes, (2) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more N-glycans contained in said exomeres, small exosomes, or large exosomes, (3) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more lipids contained in said exomeres, small exosomes, or large exosomes, (4) the presence or absence of one or more genetic mutations in nucleic acid molecules associated with cancer and contained in said exomeres, small exosomes, or large exosomes, or (5) combinations thereof. Cancer is then diagnosed, prognosed, or treatment is modified based on this information. |
| FILED | Thursday, December 15, 2022 |
| APPL NO | 18/082368 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/6893 (20130101) G01N 33/57484 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266418 | Kulam Najmudeen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Magdoom Mohamed Kulam Najmudeen (Bethesda, Maryland); Peter J. Basser (Bethesda, Maryland); Michal E. Komlosh (Bethesda, Maryland) |
| ABSTRACT | Diffusion sensitizing gradient pulse pairs are prescribed in a manner to mitigate effects of concomitant gradient artifacts. Measured MR signals generated by applying a plurality of diffusion sensitizing gradient matrices are obtained and processed to determine a second order mean diffusion tensor and a fourth order covariance tensor. Quantities derived from these tensors are measured and mapped within an imaging volume which describe features of diffusion anisotropy and heterogeneity within each imaging voxel. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 18/017150 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/022 (20130101) G01R 33/246 (20130101) G01R 33/56341 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266715 | Robinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Jeremy T. Robinson (Washington, District of Columbia); Woodruff T. Sullivan (Seattle, Washington) |
| ABSTRACT | A miniaturized apparatus for tracking the apparent motion of the sun comprising a light mask, a pixilated image sensor, and an image processing unit, wherein sunlight transmitted through the light mask allows the miniaturized apparatus to make time, latitude, direction, and date measurements. A method of making a miniaturized apparatus for tracking the apparent motion of the sun comprising the steps of providing a light mask, providing a pixilated image sensor, providing an image processing unit, and resulting in a miniaturized apparatus for tracking the apparent motion of the sun. |
| FILED | Wednesday, February 22, 2023 |
| APPL NO | 18/113044 |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) Mechanically-driven Clocks or Watches; Mechanical Parts of Clocks or Watches in General; Time Pieces Using the Position of the Sun, Moon or Stars G04B 49/02 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/246 (20170101) Pictorial Communication, e.g Television H04N 25/76 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266753 | Landry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Blake J. Landry (Saint Martinville, Louisiana); William David Null (Urbana, Illinois) |
| ABSTRACT | A system having a networking device, a plurality of processing devices, and one or more unmanned devices, wherein each unmanned device couples to a corresponding one of the processing devices, wherein each unmanned device comprises one or more operational components. The system having a controller device configured to control at least one of the one or more unmanned devices via the networking device and the corresponding one of the processing devices, the controller device comprising one of the processing devices, wherein the controlled at least one unmanned device is configurable via the corresponding processing device in a control operating mode or in a robot operating mode, the control operating mode enabling the associated unmanned device to perform commands received from the controller device via the corresponding processing device, and the robot operating mode enabling the unmanned device to receive programmable instructions from the controller device via the corresponding processing device. |
| FILED | Thursday, October 06, 2022 |
| APPL NO | 17/961382 |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0016 (20130101) Original (OR) Class G05D 1/0022 (20130101) G05D 1/0088 (20130101) G05D 2201/0207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267284 | Garg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Divyansh Garg (Stanford, California); Skanda Vaidyanath (Stanford, California) |
| ABSTRACT | Systems and methods for automated response to natural language instructions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for training an agent, the method including sampling an instruction and observation pair from a dataset, predicting a skill code, using a skill predictor, based on the instruction and observation pair, predicting, for each of a plurality of timesteps, a set of one or more actions based on the predicted skill code and a state history using a policy, and updating the skill predictor and the policy based on a comparison of the predicted set of actions and the observation. In many embodiments, the trained agent can then be used to carry out natural language instructions. |
| FILED | Wednesday, February 22, 2023 |
| APPL NO | 18/172969 |
| CURRENT CPC | Electric Digital Data Processing G06F 40/44 (20200101) G06F 40/55 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267324 | Seif Tabrizi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Seyed Alireza Seif Tabrizi (Adelphi, Maryland); Changhun Oh (Chicago, Illinois); Tao Hong (San Jose, California); Liang Jiang (Chicago, Illinois) |
| ABSTRACT | A machine learning method for model-free inference of target physical parameters from a metrology dataset is generally disclosed. The disclosed method is particularly applied to atomic interferometry for sensing/measuring physical quantities such as acceleration and rotations from measured atomic interference patterns. The method operates without a need for an exact measurement-dependent mathematical/analytical model and without a need for explicit knowledge of instrumental error processes that affect the measurement. The disclosed method is based on neural networks that are trained or calibrated to learn to simultaneously estimate the target physical quantities of interest and their measurement uncertainties. It extends the applicability of a metrology when instrumental precision is limited, and noise and imperfections are present. |
| FILED | Friday, December 23, 2022 |
| APPL NO | 18/088252 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267356 | MONROE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher MONROE (Ellicott City, Maryland); Marko CETINA (College Park, Maryland); Norbert LINKE (Stevenson, Maryland); Shantanu DEBNATH (College Park, Maryland) |
| ABSTRACT | The disclosure describes various aspects of optical control of atomic quantum bits (qubits) for phase control operations. More specifically, the disclosure describes methods for coherently controlling quantum phases on atomic qubits mediated by optical control fields, applying to quantum logic gates, and generalized interactions between qubits. Various attributes and settings of optical/qubit interactions (e.g., atomic energy structure, laser beam geometry, polarization, spectrum, phase, background magnetic field) are identified for imprinting and storing phase in qubits. The disclosure further describes how these control attributes are best matched in order to control and stabilize qubit interactions and allow extended phase-stable quantum gate sequences. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/305954 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Optical Computing Devices; G06E 1/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230267361 — Controlled Photon Fock State Generation Using Arbitrarily Weak Photonic Nonlinearities
| US 20230267361 | Clerk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Aashish Clerk (Chicago, Illinois); Andrew Lingenfelter (Chicago, Illinois) |
| ABSTRACT | A method and system that harnesses extremely weak Kerr-type nonlinearities in a single driven cavity to deterministically generate single photon Fock states, and more general photon-blockaded states are disclosed. The disclosed scheme is effective even for nonlinearities that are much smaller than photonic loss in the cavity. The disclosed scheme generates photon-blockade states that are non-Gaussian, exhibit a sharp cut-off in their photon number distribution, and can be arbitrarily close to, for example, a single-photon Fock state. This scheme relies only standard linear and parametric drives, and are hence compatible with a variety of different photonic platforms. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/161569 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267400 | Nicotera et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Nicotera (Ithaca, New York); Joseph Sirianni (Ithaca, New York); Ryan Lee Hagelstrom (Chaska, Minnesota); Robert A. Joyce (Ithaca, New York); Tyler J. Mitchell (Ithaca, New York); Kenneth McVearry (Dewitt, New York) |
| ABSTRACT | A warehouse management system may receive a predictive analytics request associated with one or more warehouses and may, in response, input data associated with the one or more warehouses into a warehouse management model to determine one or more predictive analytics associated with the one or more warehouses, where the warehouse management model is trained via machine learning to determine the predictive analytics. The warehouse management system may perform simulations of operations of the one or more warehouses based on the one or more predictive analytics to determine one or more warehouse actions to meet one or more operational requirements. The warehouse management system may communicate the one or more warehouse actions to one or more devices associated with the one or more warehouses to enable the one or more devices to operate according to the one or more warehouse actions to meet the one or more operational requirements. |
| FILED | Thursday, December 15, 2022 |
| APPL NO | 18/066782 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/08 (20130101) Original (OR) Class G06Q 10/06315 (20130101) G06Q 10/06393 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267607 | Sadri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amir Reza Sadri (Cleveland Heights, Ohio); Satish E. Viswanath (Beachwood, Ohio); Thomas Desilvio (Lyndhurst, Ohio) |
| ABSTRACT | In some embodiments, the present disclosure relates to a non-transitory computer-readable medium storing computer-executable instructions that, when executed, cause a processor to perform operations, including forming an imaging dataset having imaging data corresponding to one or more radiological images of a patient having a bowel disease; operating upon the imaging data with one or more convolutional neural network (CNN) segments configured to generate a plurality of CNN outputs, the one or more CNN segments respectively including a convolution layer configured to perform a convolution on the imaging data; and applying a wavelet network to the plurality of CNN outputs to generate a plurality of convolution wavelet network (CWN) outputs, the wavelet network being configured to decompose the plurality of CNN outputs according to a mother wavelet. A predictive signature associated with disease response or risk is constructed using the plurality of CWN outputs. |
| FILED | Thursday, February 16, 2023 |
| APPL NO | 18/169935 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10116 (20130101) G06T 2207/20064 (20130101) G06T 2207/20084 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267643 | Maryan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Corey Maryan (Bush, Louisiana); Christopher Michael (Covington, Louisiana); Steven Dennis (Covington, Louisiana); Sarah Trimble (New Orleans, Louisiana) |
| ABSTRACT | A method of identifying a rip current that includes receiving an image comprising a body of water, and identifying, in the image an estimated location of a rip current associated with the body of water, wherein the identification comprises a plurality of displayed vertices based on least one of a rip length or a rip width. The method may include digitizing the estimated location of the rip current, the estimated location having highest, lower, and no confidence boundaries. The method may include generating, based on the digitized estimated location, a set of fuzzy-set scheme labels for one or more pixels in the image based on a respective confidence boundary, where the fuzzy-set scheme labels are based on a pixel interpolation associated with the lower confidence boundary, and generating, based on the generated fuzzy-set scheme labels, a refined digitizing of the estimated location of the rip current. |
| FILED | Tuesday, February 21, 2023 |
| APPL NO | 18/112472 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 13/006 (20130101) Image Data Processing or Generation, in General G06T 7/73 (20170101) Original (OR) Class G06T 2207/10032 (20130101) G06T 2207/20061 (20130101) G06T 2207/20081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268051 | Wachs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Juan Pablo Wachs (West Lafayette, Indiana); Edgar Javier Rojas-Munoz (West Lafayette, Indiana) |
| ABSTRACT | A system and methods for artificially intelligent medical procedure assessment and intervention are provided. A system may acquire image data from a camera targeting a location where healthcare is administered. The system may receive sensor data from a sensor attached to a care provider during performance of a procedure. The system may generate gesture features based on the sensor data. The system may generate image features based on the image data. The system may determine, based on the image features and a machine learning model, a step identifier for a step in a multi-step surgical procedure. The system may access text descriptive of an instruction to perform the step. The system may display the text on a display accessible to the care provider. The system may determine, based on the gesture information and a second machine learning model, a performance metric that measures performance of the care provider. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 18/012529 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/044 (20230101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) Original (OR) Class G16H 30/40 (20180101) G16H 40/67 (20180101) G16H 70/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230269502 | Black et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nu-Trek, Inc. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Holden Black (Tennessee Ridge, Tennessee); Paul Richard Behmen (Chester, California); Francisco Tejada (Kingsville, Maryland) |
| ABSTRACT | A photodetector interface circuit is described, residing partially or fully within a unit cell per pixel of an FPA. The interface circuit uses an innovative approach to providing pixel level digitization for full frame integration times while maintaining the ability to use integration capacitors of practical sizes. The technique uses successive charge subtraction, removing charge from an integration capacitor successively, triggered by the charge increasing sufficiently to charge the integrator to a reference level, thereby triggering both charge removal and incrementing a count, until all of the current flowing in the photodetector has been accounted for and the count represents the digitization of the photodetector signal. Various options on how to arrange the digitization elements are also disclosed. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/111257 |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 25/77 (20230101) Original (OR) Class H04N 25/78 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230269530 | GHAFFARIVARDAVAGH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Reza GHAFFARIVARDAVAGH (Boston, Massachusetts); Sayed Saad AFZAL (Cambridge, Massachusetts); Osvy RODRIGUEZ (Cambridge, Massachusetts); Fadel ADIB (Cambridge, Massachusetts) |
| ABSTRACT | An ultra-wide bandwidth acoustic transducer may include multiple layers, including an inner piezoelectric layer, a polymer coupling layer and an outer piezoelectric layer. The polymer layer may be located between, and may be bonded to, the inner and outer piezoelectric layers. The transducer may have multiple eigenfrequencies of vibration. These eigenfrequencies may include primary resonant frequencies of the inner and outer piezoelectric layers respectively and may also include resonant frequencies that arise due to coupling between the layers. An acoustic backscatter system may employ such a transducer in backscatter nodes as well as in a transmitter. The multiple eigenfrequencies may enable the system to perform spread-spectrum communication at a high throughput. These multiple eigenfrequencies may also enable each backscatter node to shift frequency of an uplink signal, which in turn may enable the system to mitigate self-interference and to decode concurrent signals from multiple backscatter nodes. |
| FILED | Wednesday, April 26, 2023 |
| APPL NO | 18/139563 |
| CURRENT CPC | Transmission H04B 11/00 (20130101) H04B 13/02 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/44 (20130101) Original (OR) Class H04R 17/005 (20130101) H04R 17/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230264138 | McGrail et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | B. Peter McGrail (Pasco, Washington); Radha K. Motkuri (Richland, Washington) |
| ABSTRACT | An apparatus comprising (A) an atmospheric water extraction unit; and (B) a direct air capture unit positioned downstream of and in communication with the atmospheric water extraction unit, wherein the apparatus is capable of reversibly operating in (i) adsorption mode to adsorb water and CO2 from an incoming air stream and (ii) regeneration mode to release adsorbed water and CO2, wherein the atmospheric water extraction unit comprises a first desiccant bed comprising a sorbent that adsorbs water from an incoming air stream during adsorption mode and releases water during regeneration mode, and wherein the direct air capture unit comprises a first CO2 sorbent bed that adsorbs CO2 from an air stream during adsorption mode and releases CO2 during regeneration. |
| FILED | Tuesday, February 21, 2023 |
| APPL NO | 18/112314 |
| CURRENT CPC | Separation B01D 53/261 (20130101) B01D 53/0438 (20130101) B01D 53/0476 (20130101) Original (OR) Class B01D 2253/204 (20130101) B01D 2257/80 (20130101) B01D 2257/504 (20130101) B01D 2259/404 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264166 | BADDOUR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Frederick G. BADDOUR (Denver, Colorado); Susan E. HABAS (Boulder, Colorado); Brittney E. PETEL (Lakewood, Colorado); Alexander Kenneth YUNG (Fort Collins, Colorado) |
| ABSTRACT | The present disclosure relates to a method of synthesizing metal nanoparticles, where the method includes mixing a metal precursor with a stabilizing ligand in a first zone of a first fluidic device to form a first mixture and mixing the first mixture with a reductant in a second zone of the first fluidic device to form a second mixture, such that the metal nanoparticles form in the second zone. |
| FILED | Thursday, February 23, 2023 |
| APPL NO | 18/173317 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) Original (OR) Class B01J 2219/0086 (20130101) B01J 2219/00822 (20130101) B01J 2219/00824 (20130101) B01J 2219/00831 (20130101) B01J 2219/00833 (20130101) B01J 2219/00889 (20130101) B01J 2219/00894 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0547 (20220101) B22F 9/24 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264420 | Marshall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| ASSIGNEE(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| INVENTOR(S) | Kenneth L. Marshall (Rochester, New York); Stavros G. Demos (Rochester, New York); Tanya Kosc (Rochester, New York) |
| ABSTRACT | Additive manufacturing systems and methods utilizing an optical light valve configured to spatially modulate the intensity of a laser beam, in conjunction with a writing and erasing sub-system configured to repeatedly write and erase patterns in the optical light valve to repeatedly vary the spatial modulation of the laser beam. In some implementations, the systems and methods may also employ additional laser beams or other energy sources that are not spatially modulated by the optical light valve. In some implementations, the systems and methods may employ additional laser beams or other energy sources configured to reduce surface roughness of the powder or other material being used for additive manufacturing. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 18/004120 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/00 (20210101) B22F 10/28 (20210101) B22F 10/36 (20210101) B22F 10/38 (20210101) B22F 10/50 (20210101) B22F 10/362 (20210101) B22F 10/364 (20210101) B22F 12/13 (20210101) B22F 12/41 (20210101) B22F 12/43 (20210101) B22F 12/44 (20210101) B22F 12/45 (20210101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/064 (20151001) B23K 26/342 (20151001) B23K 26/0624 (20151001) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/00 (20170801) B29C 64/10 (20170801) B29C 64/20 (20170801) B29C 64/153 (20170801) B29C 64/268 (20170801) B29C 64/282 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230264970 | KUNO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Masaru KUNO (South Bend, Indiana); Michael BRENNAN (South Bend, Indiana); Anthony RUTH (South Bend, Indiana); Ilia PAVLOVETC (South Bend, Indiana); Jeffrey A. CHRISTIANS (Golden, Colorado); Taylor Hennessey MOOT (Golden, Colorado); Joseph Matthew LUTHER (Golden, Colorado) |
| ABSTRACT | Compositions comprise a perovskite and a non-perovskite. Perovskites comprise AxA′yA″(1−x−y)BX3, and non-perovskites may comprise A″, B and X, where A is a first cation, A′ is a second cation, A″ is a third cation, B is a fourth cation, X is an anion. In some instances, A, A′, and A″ are each independently (NH2)2CH+, CH3NH3+, Cs+, Rb+, or (NH2)2(C═NH2)+, with the proviso that A, A′, and A″ are each different. The perovskite may have a first crystal structure in which the anion is corner-sharing, the non-perovskite may have a second crystal structure comprising at least one of an orthorhombic structure, a hexagonal structure, or a perovskite-like structure, and 1−x−y may be greater than about 0.15. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 18/003776 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/005 (20130101) B05D 3/007 (20130101) B05D 2601/28 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/16 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) Organic electric solid-state devices H10K 30/10 (20230201) H10K 30/50 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265349 | BUTTS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Technology GmbH (Baden, Switzerland) |
| ASSIGNEE(S) | General Electric Technology GmbH (Baden, Switzerland) |
| INVENTOR(S) | Matthew David BUTTS (Niskayuna, New York); Weijun YIN (Niskayuna, New York); Jingjing YANG (Niskayuna, New York); Jie Jerry LIU (Niskayuna, New York) |
| ABSTRACT | Soluble water scavenger molecules for use with dielectric fluids are disclosed. An example dielectric fluid-based composition for reducing water content in a dielectric fluid may include a water-scavenging agent disposed within a dielectric fluid. The example dielectric fluid-based composition may further include the water-scavenging agent being soluble in the dielectric fluid. The example dielectric fluid-based composition may further include the water-scavenging agent being configured to react with water molecules in the dielectric fluid. The example dielectric fluid-based composition may be disposed in an electrical equipment immersed in oil. The electrical equipment may further include at least one solid insulation in operational contact with the dielectric fluid. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/676033 |
| CURRENT CPC | Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 33/04 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/14 (20130101) H01F 27/32 (20130101) H01F 27/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265572 | Kuhl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Twelve Benefit Corporation (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kendra Kuhl (Oakland, California); Etosha Cave (Berkeley, California); Nicholas Flanders (San Francisco, California); Sichao Ma (Dublin, California); Qun Zeng (Oakland, California); George Leonard (Oakland, California) |
| ABSTRACT | A system preferably including a carbon dioxide reactor. A method for carbon dioxide reactor control, preferably including selecting carbon dioxide reactor aspects based on a desired output composition, running a carbon dioxide reactor under controlled process conditions to produce a desired output composition, and/or altering the process conditions to alter the output composition. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 18/051944 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/02 (20130101) C25B 9/23 (20210101) C25B 9/70 (20210101) C25B 11/031 (20210101) C25B 15/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265822 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Michigan Technological University (Houghton, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David G. Wilson (Tijeras, New Mexico); Raymond H. Byrne (Albuquerque, New Mexico); Steven F. Glover (Albuquerque, New Mexico); Tu Anh Nguyen (Albuquerque, New Mexico); Rush D. Robinett, III (Tijeras, New Mexico); Wayne W. Weaver (Hancock, Michigan); Madelyn G. Veurink (Albuquerque, New Mexico) |
| ABSTRACT | One of the biggest challenges for all renewable energy sources (RES) is that they are variable power generators which will require reactive power or energy storage systems (ESS) to provide reliable power quality (ideally power factor of one) at the power grid generation side. The present invention is directed to a power packet network (PPN) for integrating wave energy converter (WEC) arrays into microgrids. Specifically, an array of WECs can be physically positioned such that the incoming regular waves will produce an output emulating an N-phase AC system such that the PPN output power is constant. ESS requirements are thereby minimized whilst maintaining grid stability with high power quality. This will enable RES integration onto a future smart grid for large-scale adoption and cost reduction while preserving high efficiency, reliability, and resiliency. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675064 |
| CURRENT CPC | Machines or Engines for Liquids F03B 13/1885 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/48 (20130101) H02J 3/381 (20130101) H02J 2300/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266366 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| INVENTOR(S) | Fangxing Li (Knoxville, Tennessee); Haoyuan Sun (Knoxville, Tennessee); Christopher Sticht (Key Largo, Florida); Srijib Mukherjee (Apex, North Carolina) |
| ABSTRACT | Systems and methods herein provide for sinusoidal signal distortion monitoring and visualization via a Circular Trajectory Approach (CTA). In one embodiment, a system includes a differentiator operable to differentiate an input signal from a sinusoidal signal at substantially a same fundamental frequency of the input signal. The input signal comprising a sinusoidal waveform having distortions. The system also includes a processor operable to calculate a distance index from the input signal to a derivative of the input signal to reveal distortions in the input signal, and a display operable to display the distortions in the input signal. |
| FILED | Thursday, February 23, 2023 |
| APPL NO | 18/113469 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 13/02 (20130101) Original (OR) Class G01R 19/0053 (20130101) G01R 23/167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230266413 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jing Shi (Riverside, California); Junxue Li (Riverside, California) |
| ABSTRACT | Systems and methods for spin-based detection of electromagnetic radiation at terahertz and sub-terahertz frequencies is provided. The detector can include a heterostructure and an electrical circuit. The heterostructure can include a first layer formed of an antiferromagnetic material (AFM) in contact with a second layer of a heavy metal (HM) and a third layer. The third layer can generate an effective field oriented approximately parallel to an easy axis of the first layer and approximately parallel to a propagation direction of electromagnetic radiation. The circuit can be in electrical communication with the second layer. The first layer can inject a spin current into the second layer in response to receipt of electromagnetic radiation having a sub-terahertz or terahertz frequency. The second layer can convert the injected spin current into a potential difference. The circuit can be configured to output a signal corresponding to the potential difference. |
| FILED | Wednesday, April 26, 2023 |
| APPL NO | 18/307451 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3586 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/075 (20130101) G01R 33/1284 (20130101) Original (OR) Class Electric solid-state devices not otherwise provided for H10N 50/80 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267404 | Villalobos et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jesus Rene Villalobos (Mesa, Arizona); Patrick Phelan (Scottsdale, Arizona); Levi Siwek (Tempe, Arizona); Keshawa Bandara (Tempe, Arizona); Derall Riley (Tempe, Arizona) |
| ABSTRACT | In accordance with embodiments disclosed herein, there are provided herein systems and methods for implementing aggregable, environment-controlled mini-containers for the efficient logistics of perishable products. For example, there is a system for providing efficient transportation logistics of dissimilar perishable products within a transportation unit, in which the system includes: multiple mini-containers, each being configurable to stack and aggregate to consume at least a portion of volume within the transportation unit; a Central Driving Unit (CDU) operable to provide services to each of the mini-containers to maintain the contents of each mini-container; a Central Control Unit (CCU) to receive sensor information from each of the mini-containers and further to issue control parameters for maintaining a specified atmosphere composition within each connected mini-container via the CDU, in which the CCU executes the control parameters for maintaining the specified atmosphere composition within each connected mini-container by activating actuators, in which the actuators manipulate valves at each mini-container, allowing for inflow and egress of atmospheric elements; and in which each of the multiple mini-containers constitute individual modular units configurable to form a single inter-connected and aggregated stack having a size which fits within the available volume of the transportation unit. In related embodiments, the CCU is further configured to transmit data on the status of the mini-containers to the outside world, such as transmitting status information to a remote storage location, or to the cloud, or directly to a centrally located data hub. Other related embodiments are disclosed. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 18/010357 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0832 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267658 | Jimenez, JR. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward Steven Jimenez, JR. (Albuquerque, New Mexico); Cody M. Washburn (Albuquerque, New Mexico) |
| ABSTRACT | A computer-implemented method of reconstructing boundaries from a computed tomography (CT) image dataset is provided. The method comprises receiving CT image data and applying a number of image filters to the CT image data. A numerical derivative is applied to the filtered CT image data to flatten and suppress non-edge regions that do not correspond to edges. Numerical derivative values are clipped to a specified range to reduce artifacts and noise, and an X-ray image is reconstructed according to the image filters and clipped numerical derivative values. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675434 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 11/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268085 | Taylor |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chase N. Taylor (Idaho Falls, Idaho) |
| ABSTRACT | A neutron moderator includes a porous metal hydride with channels within the porous metal hydride. Further, a method of regenerating a neutron moderator includes providing an at least partially depleted metal hydride article and introducing a hydrogen-containing gas into the at least partially depleted metal hydride article. The at least partially depleted metal hydride article includes channels. A nuclear reactor includes one or more neutron moderator regions in a core of a reactor, one or more fuel regions adjacent to the one or more neutron moderator regions, one or more heat transfer regions adjacent to the one or more fuel regions, control drums adjacent to the core, and a control rod adjacent to the core. One or more of the neutron moderator regions include a neutron moderator comprising a porous metal hydride article that has channels. |
| FILED | Tuesday, February 21, 2023 |
| APPL NO | 18/171923 |
| CURRENT CPC | Nuclear Reactors G21C 7/10 (20130101) G21C 7/24 (20130101) Original (OR) Class G21C 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268094 | Blanton et al. |
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| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Paul S. Blanton (Aiken, South Carolina); Zenghu Han (Woodridge, Illinois); Yung Y. Liu (Hinsdale, Illinois); Ronald B. Pope (Waynesboro, Pennsylvania); James M. Shuler (Germantown, Maryland) |
| ABSTRACT | The invention provides a containment structure, the containment structure comprising a vessel with an upwardly facing opening defining a periphery; a lid in rotatable and slidable communication with the periphery; and a plurality of rods contained within the lid and in slidable communication with the periphery. Also provided is a method for sealing and unsealing a containment vessel defining a body with a longitudinal axis and a lid, the method comprising simultaneously moving the lid parallel to the longitudinal axis and orthogonal to the longitudinal axis. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675604 |
| CURRENT CPC | Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/005 (20130101) G21F 5/12 (20130101) Original (OR) Class G21F 9/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268451 | CARTER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Emily A. CARTER (Belle Mead, New Jersey); Robert B. WEXLER (Philadelphia, Pennsylvania); Sai Gautam GOPALAKRISHNAN (Hamilton, New Jersey) |
| ABSTRACT | Disclosed herein are solar cells with kesterite-based absorbers that hold promise as a low-cost and durable technology to renewably produce electricity using solar energy conversion. The current state-of-the-art (SOA) for such kesterite solar cells is Cu2ZnSn(S,Se)4 and novel materials are required to suppress the formation bandgap-fluctuation- and charge-carrier-recombination-inducing defects and eventually to achieve solar cell efficiencies higher than the SOA. Three important material properties that govern the efficiency of a solar cell are the concentrations of performance-degrading defects, band gap, and chemical stability. Disclosed here is a stable material, specifically Cu2CdGe(S,Se)4, as a new candidate that can exhibit higher defect formation energies than Cu2ZnSnS4 and a nearly optimal bandgap, which can eventually result in higher solar-cell efficiencies in solar energy conversion. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 18/017544 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 19/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/068 (20130101) H01L 31/0326 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268493 | Kwon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yo Han Kwon (Atlanta, Georgia); Elsa Reichmanis (Atlanta, Georgia) |
| ABSTRACT | A composite electrode comprising a charge-conducting material, a charge-providing material bound to the charge-conducting material, and a plurality of single-walled carbon nanotubes bound to a surface of the charge-providing material. High-capacity electroactive materials that assure high performance are a prerequisite for ubiquitous adoption of technologies that require high energy/power density lithium (Li)-ion batteries, such as smart Internet of Things (IoT) devices and electric vehicles (EVs). Improved electrode performance and lifetimes are desirable. The disclosed electrode can have a Coulombic efficiency of 99% or greater, and a stable capacity retention after 100 cycles or more. Methods of making a composite electrode are disclosed. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/305470 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/386 (20130101) Original (OR) Class H01M 4/0416 (20130101) H01M 4/604 (20130101) H01M 4/622 (20130101) H01M 4/1399 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268502 | LIPSON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Albert L. LIPSON (Forest Park, Illinois); Jessica L. DURHAM (Frankfort, Illinois) |
| ABSTRACT | A stabilized lithium metal oxide cathode material comprises microparticles of lithium metal oxide in which individual particles thereof a core of lithium metal oxide and a coating of a different lithium metal oxide surrounding the core. There is an interface layer between the cores and the coatings in which there are gradients of metal ions in the direction of coating to core. The materials are made by a three stage process involving coprecipitating precursor metal hydroxide core particles at a controlled pH; coprecipitating a different metal hydroxide coating on the particles without controlling the pH; and then calcining the resulting coated precursor particles with lithium hydroxide to form the stabilized lithium metal oxide material. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/133925 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) H01M 4/0471 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 50/40 (20210101) H01M 2300/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268568 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bin Li (Idaho Falls, Idaho); Eric J. Dufek (Ammon, Idaho); Parameswara R. Chinnam (Idaho Falls, Idaho); Yulun Zhang (Salt Lake City, Utah) |
| ABSTRACT | A method of operating an energy storage device comprises applying external pressure onto an electrochemical cell during charging and/or discharging. The cell comprises a sulfur-based cathode within a compressible vessel. An energy storage system may include plates and at least one electrochemical cell that includes—within a compressible vessel—a cathode, an anode, and an electrolyte. The cathode comprises a sulfur-based active material. In a method of assembling a system for operating an energy storage device, at least one electrochemical cell is disposed between a pair of plates and adjacent pressure sensor(s). A distance between the plates is fixed at which a measured pressure is within a range from greater than about 0 kPa to about 689 kPa above ambient pressure. The plate-separation distance is maintained while charging or discharging the electrochemical cell(s). |
| FILED | Friday, July 16, 2021 |
| APPL NO | 18/005567 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 10/44 (20130101) Original (OR) Class H01M 10/0481 (20130101) H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268574 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sheng Dai (Knoxville, Tennessee); Huimin Luo (Knoxville, Tennessee); Bishnu P. Thapaliya (Knoxville, Tennessee); Tao Wang (Knoxville, Tennessee) |
| ABSTRACT | A method for processing spent nickel-based cathode material useful in lithium-based batteries, the method comprising: (i) producing an initial mixture containing the spent nickel-based cathode material and a molten salt system comprising cations and anions, wherein the cations comprise lithium cations; (ii) heating the initial mixture to a temperature of 700° C. to 900° C. for at least 1 hour to produce a relithiated cathode material; and (iii) washing the relithiated cathode material to remove any residual salt. In a further method, the cations comprise nickel and lithium cations and the anions comprise chloride or bromide anion in combination with at least one of nitrate, sulfate, and carbonate anions in further combination with hydroxide anion, wherein the method results in upcycling of the nickel-based cathode material to produce a version of said relithiated cathode material having a greater nickel content. |
| FILED | Wednesday, February 22, 2023 |
| APPL NO | 18/112646 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) H01M 4/0471 (20130101) H01M 4/525 (20130101) H01M 10/052 (20130101) H01M 10/54 (20130101) Original (OR) Class H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268678 | KHALIGH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fariborz MUSAVI (Redmond, Washington); UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alireza KHALIGH (Arlington, Virginia); Fariborz MUSAVI (Redmond, Washington) |
| ABSTRACT | In some embodiments, systems and methods for connector assembly for use with an AC or DC power interface of a power conversion device, such as a converter and an inverter, are provided. The connector assembly can include a circuit board, a power connector, and a pin. The power connector can have a base configured to be secured relative to the circuit board and define a first channel extending through the power connector along a first channel axis. The first pin can have a first pin body that extends along a first pin axis and a first connection element that extends along the first pin axis from the first pin body to a first terminal end that is skewed relative to the first pin axis. |
| FILED | Friday, April 28, 2023 |
| APPL NO | 18/309337 |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/7082 (20130101) Original (OR) Class H01R 13/2471 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/32 (20141201) H02S 40/36 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268704 | Stoll et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Trevor T. Stoll (Excelsior Springs, Missouri); Michael E. Auxier (Olathe, Kansas) |
| ABSTRACT | A demating device configured to demate an electrical connector assembly having a first connector and a second connector is provided. The demating device may include a first separating member, a second separating member, and a gripping assembly. Actuation of the first separating member and the second separating member towards one another drives the jaws of the gripping assembly together, therein allowing secure gripping of the electrical connector assembly via the demating device for separation of the first and second connectors. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678637 |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/633 (20130101) H01R 43/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268705 | Hatch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing & Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen McGarry Hatch (Blue Springs, Missouri); James Alexander Zandstra (Long Beach, California) |
| ABSTRACT | Electrical connector assembly devices, systems, and methods including a demating device configured to separate a first connector and a second connector of an electrical connector assembly. The demating device includes a housing body, a drive assembly including: a drive lever, a trigger configured to push against the drive lever, a drive assembly rod, and a spring mounted around the drive assembly rod; and a demating assembly including: a movable plate having at least two sides, wherein each of the two sides includes at least two prongs; a stationary plate having at least two sides, wherein each of the two sides includes at least two prongs; and a rotary actuator configured to rotate the movable plate. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678680 |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/635 (20130101) H01R 13/6335 (20130101) H01R 43/22 (20130101) H01R 43/26 (20130101) Original (OR) Class H01R 43/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268709 | Diroll |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin Diroll (Chicago, Illinois) |
| ABSTRACT | Optical gain mediums are required for lasing devices and high intensity optical systems across a wide range of applications. A method for achieving optical gain includes an optical gain medium having colloidal quantum fountains includes providing pump radiation to the gain medium. The electrons of the colloidal quantum fountains are promoted from a valence band to an excited state in a conduction band of the colloidal quantum fountains. Seed radiation is provided to the gain medium and electrons of the quantum fountains are de-excited by the seed radiation through stimulated emission from the excited state to a lower energy state of the conduction band, thereby providing optical gain. |
| FILED | Monday, February 21, 2022 |
| APPL NO | 17/676307 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/169 (20130101) H01S 3/094096 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268721 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma); Sandia National Laboratories (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rui Q. Yang (Norman, Oklahoma); John F. Klem (Albuquerque, New Mexico) |
| ABSTRACT | An ICL comprises: a plurality of IC stages, wherein each of the IC stages comprises: a hole injector; an electron injector; an active region coupled to the hole injector and the electron injector and comprising a first layer, wherein the first layer comprises a first material, and wherein the first material comprises InAsP or AlInAsP; a conduction band running through the hole injector, the electron injector, and the active region; and a valence band running through the hole injector, the electron injector, and the active region. |
| FILED | Monday, February 13, 2023 |
| APPL NO | 18/168337 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/3402 (20130101) Original (OR) Class H01S 5/3422 (20130101) H01S 5/34306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268882 | GOSTEIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael GOSTEIN (Austin, Texas); William STUEVE (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael GOSTEIN (Austin, Texas); William STUEVE (Austin, Texas) |
| ABSTRACT | In one respect, disclosed is a device comprising terminals or connections configured to connect to a first associated PV module, I-V measurement circuitry coupled to said terminals or connections and configured to measure I-V data of said first associated PV module, communication circuitry configured to communicate with at least one external device, and a processor coupled to said I-V measurement circuitry and to said communication circuitry, wherein said processor is configured to receive external data via said communication circuitry from said at least one external device, and wherein said processor is configured to determine a relative performance metric based at least upon said I-V data of said first associated PV module and said external data. In another respect, disclosed is a system comprising a first device configured to measure first I-V data of a first associated PV module and a second device configured to measure second I-V data of a second associated PV module, wherein said first device may be configured to receive said second I-V data and to determine a relative performance metric based at least upon said second I-V data and said first I-V data. |
| FILED | Tuesday, April 04, 2023 |
| APPL NO | 18/130558 |
| CURRENT CPC | Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 50/15 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20230263164 | Bowden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Ned B. Bowden (Iowa City, Iowa); Justin M. CARTER (Iowa City, Iowa); Eric M. BROWN (Iowa City, Iowa); Nimesh RANASINGHE (Iowa City, Iowa); Arjun PAUDEL (Iowa City, Iowa); Erin E. IRISH (Iowa City, Iowa) |
| ABSTRACT | The invention provides a compound of formula (I): wherein X, Y Z, R1, R2, and X+ have any of the values described in the specification. The compounds are useful to increase plant growth and/or to increase harvest yield. |
| FILED | Monday, August 30, 2021 |
| APPL NO | 18/024034 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 57/12 (20130101) Original (OR) Class A01N 57/16 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 21/00 (20210801) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/06 (20130101) C07F 9/6578 (20130101) C07F 9/657118 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263176 | Farcuh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Macarena Farcuh (Silver Spring, Maryland); Rohan Tikekar (Silver Spring, Maryland); Joseph H. Sullivan (Brookeville, Maryland); Yixin Cai (College Park, Maryland); Abraham Moses Monteymayor (Washington, District of Columbia) |
| ABSTRACT | Provided herein are methods relating to ultraviolet irradiation of apples to improve their color and safety. The methods allow harvesting apples at optimum maturity, without having to delay waiting for color. The methods result in a significant increase in red skin coloration and suppression of L. monocytogenes without impairing fruit quality attributes during commercial storage. |
| FILED | Friday, February 03, 2023 |
| APPL NO | 18/164325 |
| CURRENT CPC | Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 7/015 (20130101) Original (OR) Class Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/28 (20130101) A23L 19/03 (20160801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263190 | Ulmasov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COVERCRESS INC. (ST. LOUIS, Missouri); BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (Normal, Illinois); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tim Ulmasov (St. Louis, Missouri); Gary Hartnell (St. Peters, Missouri); John C. Sedbrook (Bloomington, Illinois); Michael David Marks (Roseville, Minnesota); Ratan Chopra (St. Louis, Missouri); Maliheh Esfahanian (Stanford, California) |
| ABSTRACT | Pennycress seed, seed lots, and seed meal having reduced fiber content and improved suitability for use in producing animal feed are provided. |
| FILED | Thursday, March 16, 2023 |
| APPL NO | 18/185195 |
| CURRENT CPC | Fodder A23K 10/30 (20160501) Original (OR) Class A23K 20/158 (20160501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265450 | Ulmasov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COVERCRESS INC. (ST. LOUIS, Missouri); BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (Normal, Illinois); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tim Ulmasov (St. Louis, Missouri); John C. Sedbrook (Bloomington, Illinois); Michael David Marks (Roseville, Minnesota); Ratan Chopra (St. Louis, Missouri) |
| ABSTRACT | Pennycress (Thlaspi arvense) seed, seed lots, seed meal, and compositions with reduced glucosinolate content as well as plants that yield such seed, seed lots, seed meal, and compositions are provided. Methods of making and using the pennycress plants and/or seed that provide such seed, seed lots, seed meal, and compositions are also provided. |
| FILED | Thursday, March 16, 2023 |
| APPL NO | 18/185179 |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/10 (20130101) A01H 6/20 (20180501) Fodder A23K 10/30 (20160501) A23K 40/10 (20160501) A23K 50/10 (20160501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265529 | Singh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida); The United State of America, as presented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prashant Singh (Tallahassee, Florida); Joseph M. Bosilevac (Clay Center, Nebraska) |
| ABSTRACT | Disclosed herein are methods and kits for quantifying the presence of a microorganism in a sample. Specifically, disclosed are methods for quantifying a pathogen in a sample, such as a food sample, to determine if the levels of pathogen present in the sample are within an acceptable range. |
| FILED | Friday, November 11, 2022 |
| APPL NO | 18/054778 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230263398 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cha-Min Tang (Wayne, Pennsylvania); Joseph Schmitt (Cupertino, California) |
| ABSTRACT | An apparatus provided for detecting tooth pulp vitality includes a handle, a pivot and a caliper. A pair of fiber optic lines pass through an interior of the handle, the pivot and the caliper. One of the fiber optic lines is a source line with a connector at an end of the source line and another of the fiber optic lines is a detector line with a connector at an end of the detector line. The source line is single mode in the handle and the detector line is multi mode. A system is also provided for detecting tooth pulp vitality that includes the apparatus. Additionally, a method is provided for detecting tooth pulp vitality that employs the apparatus. |
| FILED | Friday, April 21, 2023 |
| APPL NO | 18/304711 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/0088 (20130101) Original (OR) Class A61B 5/0261 (20130101) A61B 5/682 (20130101) A61B 5/4547 (20130101) A61B 2090/3614 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263943 | Myung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States Government as represented by the Department of Veterans Affairs (NW Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Myung (Saratoga, California); Fang Chen (Stanford, California); Gabriella Fernandes-Cunha (Palo Alto, California); Sarah Hull (Stanford, California); Sarah Heilshorn (Mountain View, California); Christopher Lindsay (San Mateo, California); Christopher Madl (Los Altos, California); Hyun Jong Lee (Gyeonggi-do, South Korea) |
| ABSTRACT | Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined hydrogel structure in situ, including interpenetrating (IPN) and semi-IPN hydrogels. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/997097 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/142 (20130101) A61F 2210/0085 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 2400/06 (20130101) A61L 2430/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265121 | Marx et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina); Department of Veterans Affairs (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christine Marx (Durham, North Carolina); Robert Mook (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides modified neuroactive steroids. The modified neuroactive steroids may comprise, consist of, or consist essentially of a therapeutic agent and/or a modifying moiety. The modified neuroactive steroid can have modified characteristics as compared to native neuroactive steroids that do not include a modifying moiety and/or therapeutic agent. The modified neuroactive steroid may be, for example, modified pregnenolone, pregnenolone metabolites, allopregnanolone, and/or allopregnanolone metabolites. The modified neuroactive steroids can be used to treat, prevent and/or ameliorating a phenotypic state of interest in a subject. |
| FILED | Tuesday, June 21, 2022 |
| APPL NO | 17/807891 |
| CURRENT CPC | Steroids C07J 7/001 (20130101) Original (OR) Class C07J 7/007 (20130101) C07J 7/0045 (20130101) C07J 13/007 (20130101) C07J 31/006 (20130101) C07J 41/0005 (20130101) C07J 41/005 (20130101) C07J 43/003 (20130101) C07J 51/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230263565 | Borsic |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NE Scientific, LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | NE Scientific, LLC (Boston, Massachusetts) |
| INVENTOR(S) | Andrea Borsic (Torino, Italy) |
| ABSTRACT | A system for ablation treatment of tissues including at least one tissue ablation device, an ablation device controller communicatively connected to the at least one tissue ablation device, and an imaging component, wherein the imaging component is configured to capture a captured image that includes a representation of the tissue ablation device. The system further including an ablation device identification component configured to receive the captured image, generate a plurality of region proposals from the captured image, extract a plurality of feature vectors from the plurality of region proposals, determine a class for each region proposal of the plurality of region proposals, and determine the position and orientation of the tissue ablation device as a function of the classes for each region proposal. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/890839 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/1206 (20130101) Original (OR) Class A61B 18/1815 (20130101) A61B 34/25 (20160201) A61B 90/37 (20160201) A61B 2018/00577 (20130101) A61B 2018/1861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230263932 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Embody, Inc. (Norfolk, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert S. Brown (Norfolk, Virginia); Caitlin Harclerode (Norfolk, Virginia); Nardos Sori (Norfolk, Virginia); Michael P. Francis (Norfolk, Virginia); Nicholas Thayer (Morrisville, North Carolina) |
| ABSTRACT | An implantable biopolymer scaffold includes at least one braided strand comprising high strength collagen fibers and synthetic fibers, wherein the collagen fibers have a greater cross-sectional deform ability than the synthetic fibers. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/167051 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 17/08 (20130101) A61L 17/14 (20130101) Original (OR) Class A61L 17/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230265516 | GARCIA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF ARIZONA, ARIZONA BOARD OF REGENTS (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joe G.N. GARCIA (Tucson, Arizona); Mohamed n. AHMED (Tucson, Arizona) |
| ABSTRACT | A method of identifying single nucleotide polymorphisms (SNPs) within the NAMPT promoter that are associated with an inflammatory condition, such as cardiac ischemia, traumatic brain injury, cancer, chorioamnionitis, nonalcoholic steatohepatitis (NASH), or renal fibrosis. Also provided are methods of diagnosing and treating such inflammatory condition in a subject. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 18/040976 |
| CURRENT CPC | Peptides C07K 16/40 (20130101) C07K 2317/565 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20230265497 | Dhingra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mission Bio, Inc. (South San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dalia Dhingra (South San Francisco, California); David Ruff (South San Francisco, California) |
| ABSTRACT | Disclosed herein is a single-cell analysis workflow involving whole genome amplification for developing single-cell whole genome DNA libraries. The single-cell analysis workflow involves encapsulating and lysing cells in individual droplets and releasing genomic DNA from chromatin within the droplet. Transposases access the released genomic DNA and insert adaptor sequences into the cleaved nucleic acid fragments, thereby generating tagmented genomic DNA fragments that span the whole genome. Tagmented genomic DNA undergo nucleic acid amplification and sequencing for generating single-cell whole genome DNA libraries. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/912689 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 7/52 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230267356 | MONROE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher MONROE (Ellicott City, Maryland); Marko CETINA (College Park, Maryland); Norbert LINKE (Stevenson, Maryland); Shantanu DEBNATH (College Park, Maryland) |
| ABSTRACT | The disclosure describes various aspects of optical control of atomic quantum bits (qubits) for phase control operations. More specifically, the disclosure describes methods for coherently controlling quantum phases on atomic qubits mediated by optical control fields, applying to quantum logic gates, and generalized interactions between qubits. Various attributes and settings of optical/qubit interactions (e.g., atomic energy structure, laser beam geometry, polarization, spectrum, phase, background magnetic field) are identified for imprinting and storing phase in qubits. The disclosure further describes how these control attributes are best matched in order to control and stabilize qubit interactions and allow extended phase-stable quantum gate sequences. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/305954 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Optical Computing Devices; G06E 1/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20230266237 | GAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NOAA, US DEPARTMENT OF COMMERCE (Silver Spring, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | RU-SHAN GAO (BOULDER, Colorado); STEVEN CICIORA (SUPERIOR, Colorado) |
| ABSTRACT | Embodiments of the present invention relate to an apparatus for detecting ozone in ambient air, including an absorption cell with a bounded chamber for receiving air sample for analysis, a light source positioned to transmit light through absorption cell, a detector positioned to measure the attenuation of light passing through absorption cell, a pumping system for transporting ambient air into chamber and then reversing direction to transport ozone-free air into the absorption cell for purging the chamber, a scrubber positioned downstream from outlet port of the absorption cell to remove ozone from sample air exiting the absorption cell, a relative humidity (RH) equalizer for controlling humidity of sample air exiting absorption cell such that the sample entering scrubber has relatively the same humidity as ambient air, and a data system for digitizing and processing output from detector. |
| FILED | Wednesday, January 04, 2023 |
| APPL NO | 18/093008 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/24 (20130101) G01N 1/2273 (20130101) G01N 1/4077 (20130101) G01N 21/33 (20130101) Original (OR) Class G01N 2001/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20230264504 | Zlotnick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Joel Zlotnick (Arlington, Virginia); Tyra McConnell (Knoxville, Maryland); Traci Moran (Rockville, Maryland); Jordan Brough (Leesburg, Virginia); Troy Eberhardt (Centreville, Virginia); Elizabeth Gil (Bristow, Virginia) |
| ABSTRACT | A security system for an article of manufacture includes one or more first planchettes and one or more second planchettes included in the article. The first planchettes luminesce under a first frequency of light and the second planchettes luminesce under a second frequency of light with at least one of three characteristics. First, the first frequency is different from the second frequency, the first planchettes do not luminesce under the second frequency of light, and the second planchettes do not luminesce under the first frequency of light. Second, the first planchettes luminesce at a first color under the first frequency of light and the second planchettes luminesce at a second color different from the first color under the second frequency of light. Third, the first planchettes reflect a first pattern under the first frequency of light and the second planchettes reflect a second pattern under the second frequency of light. |
| FILED | Thursday, January 26, 2023 |
| APPL NO | 18/102002 |
| CURRENT CPC | Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 3/14 (20130101) Original (OR) Class Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/20 (20141001) B42D 25/355 (20141001) B42D 25/387 (20141001) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
| US 20230264510 | Rich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WAVEFRONT TECHNOLOGY, INC. (Paramount, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Chapman Rich (Rancho Palos Verdes, California); Joel Mikael Petersen (Valley Village, California); Roger Winston Phillips (Santa Rosa, California); John Michael Tamkin (Pasadena, California) |
| ABSTRACT | An optical device includes an array of lenses and a plurality of segments disposed under the array of lenses. The plurality of segments corresponds to a plurality of images. Upon tilting the device at different viewing angle, the array of lenses presents images sequentially. In some examples, individual ones of the segments can comprise specular reflecting, transparent, diffusely reflecting, and/or diffusely transmissive features. In some examples, individual ones of the segments can comprise transparent and non-transparent regions. The images can produce one or more optical effects. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/822413 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/08 (20130101) B32B 3/30 (20130101) B32B 7/06 (20130101) B32B 27/08 (20130101) B32B 27/32 (20130101) B32B 27/36 (20130101) B32B 27/285 (20130101) B32B 27/302 (20130101) B32B 27/304 (20130101) B32B 27/365 (20130101) B32B 2250/24 (20130101) B32B 2255/20 (20130101) B32B 2255/26 (20130101) B32B 2255/28 (20130101) B32B 2255/205 (20130101) B32B 2307/40 (20130101) B32B 2307/41 (20130101) B32B 2307/204 (20130101) B32B 2307/402 (20130101) B32B 2307/408 (20130101) B32B 2307/412 (20130101) B32B 2307/422 (20130101) B32B 2307/732 (20130101) B32B 2307/4023 (20130101) B32B 2307/4026 (20130101) B32B 2425/00 (20130101) Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/21 (20141001) B42D 25/324 (20141001) B42D 25/328 (20141001) B42D 25/351 (20141001) Original (OR) Class B42D 25/373 (20141001) B42D 25/378 (20141001) Special Designs or Pictures B44F 1/045 (20130101) Optical Elements, Systems, or Apparatus G02B 3/0056 (20130101) G02B 27/06 (20130101) G02B 30/27 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 20230264986 | Sahu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abhispa Sahu (Charlotte, North Carolina); Jordan C. Poler (Charlotte, North Carolina) |
| ABSTRACT | Nanocomposite materials are described herein which, in some embodiments, are employed as separation media for removal of various contaminants from water sources, including heavy metals, PFAS and/or NOM. In some embodiments, a nanocomposite material comprises oligomeric chains or polymeric chains covalently attached to surfaces of fluorographite at sites of defluorination. In another aspect, nanocomposite materials based on cellulose nanofibers are described herein. In some embodiments, a nanocomposite material comprises oligomeric chains or polymeric chains covalently attached to surfaces of cellulose nanofibers. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 18/020694 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/24 (20130101) B01J 20/205 (20130101) B01J 20/265 (20130101) B01J 20/3255 (20130101) B01J 20/3293 (20130101) B01J 20/28016 (20130101) B01J 2220/46 (20130101) B01J 2220/4806 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/42 (20130101) Original (OR) Class C02F 2001/422 (20130101) C02F 2001/425 (20130101) C02F 2101/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20230264827 | GURUSWAMY |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Guru Pillappa GURUSWAMY (Sunnyvale, California) |
| ABSTRACT | A system can include a controller that can generate a query request in response to an instantaneous roll angle of a vertical take off and landing (VTOL) aircraft being equal to or greater than a roll angle threshold. The instantaneous roll angle being equal to or greater than the roll angle threshold can indicate that the VTOL aircraft has deviated or is about to deviate from a current stable aircraft state. A database can provide propeller control data identifying a propeller speed profile for at least one propeller of the VTOL aircraft in response to the query request. The database can store different propeller speed profiles for at least some propellers of the VTOL aircraft for respective roll angles. The controller can cause the at least one propeller of the VTOL aircraft to rotate at the propeller speed to return the VTOL aircraft to the stable aircraft state. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/171268 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 29/0025 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 31/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20230267408 | Dixon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert E. Dixon (Washington, District of Columbia); Ryan Luckay (Washington, District of Columbia) |
| ABSTRACT | A receptacle for detecting delivery and retrieval events has a door sensor, an item sensor, a scanner, and a control unit for operating the sensors, and transmitting the sensor information for processing and analysis. A system can determine whether an event was a delivery or retrieval event based on sensor information and item tracking information. A system can further include an item configured to interact with a computing device. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/166912 |
| CURRENT CPC | Household or Table Equipment A47G 29/141 (20130101) A47G 2029/145 (20130101) A47G 2029/146 (20130101) A47G 2029/149 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 19/06028 (20130101) G06K 2019/06253 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20230265762 | Krumanaker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Lee Krumanaker (Blue Ash, Ohio); Thomas Joseph Lipinski (Monroe, Ohio) |
| ABSTRACT | A turbine engine comprising an engine core, a plurality of circumferentially arranged vanes, and a floating seal. The plurality of circumferentially arranged vanes forming an upper band and a lower band. The floating seal being carried by at least one respective vane of the plurality of circumferentially arranged vanes. The floating seal having a ring and at least one dynamic seal. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/072921 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/025 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230268312 | Wallace et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Peter M. Wallace (Newfields, New Hampshire); Daniel E. Mendoza (Leominster, Massachusetts) |
| ABSTRACT | A pressure collet that operably engages with a die in which the pressure collet is configured to land on predetermined positions of the die without damaging said die, a perform, or a heat spreader during a reflow process. The pressure collet further comprises a plate that has a mounting surface and a plurality of contact pads that operably engages with the mounting surface of the plate. The plurality of contact pads is configured to apply pressure to predetermined positions of a die without the mounting surface of the plate contacting the die during a reflow process. The plate of the pressure collet is also formed of a first material and the plurality of contact pads are formed of a second material different than the first material. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675600 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0012 (20130101) B23K 1/0016 (20130101) B23K 3/087 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/75 (20130101) Original (OR) Class H01L 24/81 (20130101) H01L 24/83 (20130101) H01L 2224/7532 (20130101) H01L 2224/75312 (20130101) H01L 2224/75318 (20130101) H01L 2224/81203 (20130101) H01L 2224/81815 (20130101) H01L 2224/83203 (20130101) H01L 2224/83815 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, August 24, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230824.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page