FedInvent™ Patent Applications

Application Details for Thursday, August 24, 2023 

This page was updated on Thursday, August 24, 2023 at 03:58 PM GMT

Department of Health and Human Services (HHS) 

US 20230263232 FUEMMELER et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia);  PENNINGTON BIOMEDICAL RESEARCH INSTITUTE (Baton Rouge, Louisiana);  EAST CAROLINA UNIVERSITY (Greenville, North Carolina)
ASSIGNEE(S)
INVENTOR(S) Bernard FUEMMELER (Henrico, Virginia);  Thomas EISSENBERG (Henrico, Virginia);  Corby MARTIN (Baton Rouge, Louisiana);  Eric SOULE (Greenville, North Carolina)
ABSTRACT Provided are systems and methods of identifying the functional characteristics and operational settings of any electronic inhalants or apparatuses that are designed to provide nicotine vapors to a user. The system includes a mobile device having a built-in camera to receive images of a nicotine delivery device, a system of remote backend servers with at least one image database for identifying the nicotine delivery device, and at least one processor for calculating an amount of nicotine delivered by the nicotine delivery device.
FILED Tuesday, July 27, 2021
APPL NO 18/005624
CURRENT CPC
Smokers\' Requisites; Match Boxes; Simulated Smoking Devices
A24F 40/50 (20200101) Original (OR) Class
A24F 40/60 (20200101)
A24F 40/65 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263455 CHIANG et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Board Of Regents of The University of Texas System (Austin, Texas)
ASSIGNEE(S)
INVENTOR(S) Florence Yi Yi Ling CHIANG (San Antonio, Texas);  Peter T. FOX (San Antonio, Texas);  Rebecca S. Romero (San Antonio, Texas);  Larry PRICE (San Antonio, Texas)
ABSTRACT Provided here are non-invasive methods for evaluating functional connectivity patterns in localized brain regions of a patient involving application of a MS-specific functional meta-analytic connectivity model in resting-state functional magnetic resonance imaging (rsfMRI) data to provide patients with appropriate medical care in response to output from the model.
FILED Saturday, May 29, 2021
APPL NO 18/000157
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/72 (20130101)
A61B 5/4064 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263551 Bankiewicz
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S)
INVENTOR(S) Krystof S. Bankiewicz (Oakland, California)
ABSTRACT The use of stepped cannulas, wherein a step structure creates a backstop to reduce backflow along the cannula body, is known for convection enhanced delivery of agents to the brain and other structures within an animal. Described herein are novel and improved stepped cannula designs wherein the length of the cannula segment between the step and the dispensing outlet is variable and can be controllably adjusted inside the patient during delivery. This advantageously allows the operator to place the cannula step at the optimal position and deliver agents at one or more positions within the target structure.
FILED Wednesday, January 25, 2023
APPL NO 18/101455
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/12 (20130101)
A61B 17/3421 (20130101) Original (OR) Class
A61B 17/3478 (20130101)
A61B 2017/00991 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/46 (20130101)
A61M 5/158 (20130101)
A61M 5/3286 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263565 Borsic
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) NE Scientific, LLC (Boston, Massachusetts)
ASSIGNEE(S) NE Scientific, LLC (Boston, Massachusetts)
INVENTOR(S) Andrea Borsic (Torino, Italy)
ABSTRACT A system for ablation treatment of tissues including at least one tissue ablation device, an ablation device controller communicatively connected to the at least one tissue ablation device, and an imaging component, wherein the imaging component is configured to capture a captured image that includes a representation of the tissue ablation device. The system further including an ablation device identification component configured to receive the captured image, generate a plurality of region proposals from the captured image, extract a plurality of feature vectors from the plurality of region proposals, determine a class for each region proposal of the plurality of region proposals, and determine the position and orientation of the tissue ablation device as a function of the classes for each region proposal.
FILED Thursday, August 18, 2022
APPL NO 17/890839
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/1206 (20130101) Original (OR) Class
A61B 18/1815 (20130101)
A61B 34/25 (20160201)
A61B 90/37 (20160201)
A61B 2018/00577 (20130101)
A61B 2018/1861 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263627 Kheradvar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)
INVENTOR(S) Arash Kheradvar (Irvine, California);  Daryl C. Nguyen (Irvine, California)
ABSTRACT A growth-accommodating prosthetic valve system that can accommodate a patient's growth over time. The system features an expandable stent that can expand from a contracted configuration to an expanded configuration and leaflets attached to the scaffold that is sewn along a path such that the length of the path stays generally the same as the scaffold moves from the contracted configuration to the expanded configuration.
FILED Thursday, April 27, 2023
APPL NO 18/308239
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/2418 (20130101) Original (OR) Class
A61F 2/2433 (20130101)
A61F 2210/0057 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263688 Young et al.
FUNDED BY
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)
INVENTOR(S) Aaron Young (Atlanta, Georgia);  Inseung Kang (Atlanta, Georgia);  Dawit Lee (Atlanta, Georgia)
ABSTRACT An exemplary embodiment of the present disclosure provides a knee exoskeleton comprising a first interface, a second interface, an actuator, and a controller. The first interface can be configured to interface with a portion of a leg of a user above a knee joint of the user. The second interface can be configured to interface with a portion of the leg of the user below the knee joint of the user. The actuator can be configured to generate a torque to cause a movement of at least one of the first and second interfaces. The controller can be configured to control the actuator to vary the magnitude of torque generated by the actuator.
FILED Thursday, July 01, 2021
APPL NO 18/003927
CURRENT CPC
Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 3/00 (20130101) Original (OR) Class
A61H 2003/007 (20130101)
A61H 2201/164 (20130101)
A61H 2201/165 (20130101)
A61H 2201/1628 (20130101)
A61H 2230/625 (20130101)
A61H 2230/655 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263729 Scott et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S)
INVENTOR(S) Evan A. Scott (Northfield, Illinois);  Guillermo A. Ameer (Chicago, Illinois);  Jacqueline A. Burke (Chicago, Illinois);  Sean D. Allen (Chicago, Illinois);  Sijia Yi (Evanston, Illinois)
ABSTRACT Provided herein are nanocarriers for delivery of immunosuppressive agents. In some embodiments, provided herein are nanocarriers comprising a core comprising a poly(ethylene glycol)-block-poly(propylene sulfide) copolymer and least one therapeutic agent. In some embodiments, the nanocarriers may further comprise a targeting ligand displayed on a surface of the nanocarrier. The at least one therapeutic agent may be an anti-inflammatory agent. The disclosed nanocarriers may be incorporated into pharmaceutical compositions for use in methods of treating an inflammatory condition or preventing transplantation rejection in a subject.
FILED Thursday, March 02, 2023
APPL NO 18/177694
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/1273 (20130101) Original (OR) Class
A61K 31/192 (20130101)
A61K 31/436 (20130101)
A61K 31/593 (20130101)
A61K 47/60 (20170801)
A61K 47/64 (20170801)
A61K 47/543 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)
A61P 41/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263741 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Emory University (Atlanta, Georgia)
ASSIGNEE(S)
INVENTOR(S) Lily Yang (Atlanta, Georgia);  Xiangxue Guo (Atlanta, Georgia);  Hui Mao (Johns Creek, Georgia);  Wei Chen (Atlanta, Georgia)
ABSTRACT This disclosure relates to nanoparticles coated with fusion proteins comprising a domain that binds a cancer marker and a domain comprising a toxic polypeptide. In certain embodiments, the targeted cancer marker is urokinase plasminogen activator receptor (uPAR) insulin-like growth factor 1 receptor (IGF1R), EGFR, HER2, and/or other member of the ErbB family of receptors. In certain embodiments, the molecule that binds a cancer marker is an amino terminal fragment of uPA or variant capable of binding uPAR and/or IGF1 or variant capable of binding IGF1R. In certain embodiments, the toxic polypeptide is a bacterial exotoxin.
FILED Monday, March 13, 2023
APPL NO 18/182682
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/51 (20130101) Original (OR) Class
A61K 38/00 (20130101)
A61K 47/6415 (20170801)

Peptides
C07K 14/65 (20130101)
C07K 16/30 (20130101)
C07K 16/2863 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/6462 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263774 HUARD et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Steadman Philippon Research Institute (Vail, Colorado)
ASSIGNEE(S) Steadman Philippon Research Institute (Vail, Colorado)
INVENTOR(S) Johnny HUARD (Edwards, Colorado);  Marc Joseph PHILIPPON (Edwards, Colorado)
ABSTRACT The present disclosure provides methods for enhancing a therapeutic outcome in a subject having a musculoskeletal condition or disorder, comprising administering at least one senolytic agent and/or at least one anti-fibrotic agent to the subject.
FILED Friday, July 30, 2021
APPL NO 18/040959
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/353 (20130101)
A61K 31/4178 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/00 (20180101)
A61P 19/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263776 Johnson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S)
INVENTOR(S) Bankole A. Johnson (Charlottesville, Virginia)
ABSTRACT Compositions and methods are provided that are useful for diagnosing, treating, and monitoring alcohol dependence and disorders, susceptibility to alcohol dependence disorders, as well as drug related dependence and disorders. The methods include treating patients with an antagonist of the serotonin receptor 5-HT3 for such disorders, wherein the patient's serotonin transporter gene SLC6A4 is known to have particular genotypes.
FILED Thursday, March 23, 2023
APPL NO 18/188755
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4178 (20130101) Original (OR) Class
A61K 31/7048 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 1/6888 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/172 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263783 Yaffe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Michael B. Yaffe (West Roxbury, Massachusetts);  Brian A. Joughin (Cambridge, Massachusetts);  Jesse C. Patterson (Natick, Massachusetts)
ABSTRACT An effective amount of one or more microtubule polymerization inhibitors is administered in combination with one or more polo-like kinase (Plk) inhibitors for treating cancer. Administration of the combination of the active agents can be effective to reduce cancer cell proliferation or viability in a subject with cancer to the same degree, or a greater degree, than administering to the subject the same amount of either active agent alone. The active agents can be administered together or separately. Methods of selecting and treating subjects with cancers are also provided.
FILED Tuesday, December 13, 2022
APPL NO 18/065348
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0056 (20130101)
A61K 31/40 (20130101)
A61K 31/437 (20130101) Original (OR) Class
A61K 31/5025 (20130101)
A61K 31/5365 (20130101)
A61K 51/0463 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263797 Deretic et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNM Rainforest Innovations (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Vojo P. Deretic (Placitas, New Mexico);  Graham Timmins (Albuquerque, New Mexico);  Suresh Kumar (Albuquerque, New Mexico)
ABSTRACT The present invention is directed to elucidating the mechanism of formation of autophagosomal membranes that emerge via convergence of secretory and endosomal pathways and providing therapeutic approaches to the treatment of several acute respiratory syndrome coronavirus 1 (SARS) and 2 SARS-CoV-2), MERS-CoV and numerous other autophagy-mediated diseases based upon this mechanism. This process is targeted by microbial factors such as coronaviral membrane modulating proteins and represents a potential target for agents which may be used in the treatment of SARS, COVID and MERS. The present invention is also directed to compositions and methods for the treatment of SARS, COVID and/or MERS and other autophagy-mediated disease states.
FILED Thursday, August 25, 2022
APPL NO 17/895849
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/03 (20130101)
A61K 31/135 (20130101)
A61K 31/495 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263800 Dudakov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Fred Hutchinson Cancer Center (Seattle, Washington)
ASSIGNEE(S) Fred Hutchinson Cancer Center (Seattle, Washington)
INVENTOR(S) Jarrod Dudakov (Seattle, Washington);  Sinead Kinsella (Seattle, Washington);  Lorenzo Iovino (Seattle, Washington)
ABSTRACT Compositions and methods to promote thymic function are described. The compositions and methods can activate the GPR39 receptor and/or a purinergic receptor, such as P2Y2. The activation can upregulate regenerative molecules, such as FOXN1, interleukin (IL)-22, IL-23, and bone morphogenetic protein 4 (BMP4).
FILED Wednesday, November 03, 2021
APPL NO 18/043303
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/351 (20130101)
A61K 31/365 (20130101)
A61K 31/506 (20130101) Original (OR) Class
A61K 31/675 (20130101)
A61K 31/4184 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263817 Tian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Rong Tian (Seattle, Washington);  Dennis Ding-Hwa Wang (Seattle, Washington);  Bo Zhou (Seattle, Washington);  Kevin Douglas O'Brien (Seattle, Washington)
ABSTRACT The current disclosure provides use of high dose nicotinamide adenine dinucleotide (NAD) precursor regimens for reduction of inflammation in human patients with preexisting inflammation. The NAD precursor can be nicotinamide riboside (NR) and the high dose regimen can include at least 1000 or 2000 mg/day for at least 9 days.
FILED Friday, August 27, 2021
APPL NO 18/024032
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/706 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 29/00 (20180101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5094 (20130101)
G01N 33/6869 (20130101)
G01N 2333/545 (20130101)
G01N 2333/5412 (20130101)
G01N 2800/325 (20130101)
G01N 2800/7095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263829 Honkanen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of South Alabama Foundation for Research and Commercialization (Mobile, Alabama)
ASSIGNEE(S)
INVENTOR(S) Richard Eric Honkanen (Mobile, Alabama);  Brandon Marshall D'Arcy (Mobile, Alabama);  Mark Raymond Swingle (Mobile, Alabama)
ABSTRACT Compositions, methods, and systems for modifying sterol metabolism in a subject is disclosed. In some embodiments, the subjects may be administered one or more mammalian cells modified to express at least one sterol degrading enzyme derived from a bacterium. In many embodiments, the cell is a macrophage or monocyte stably expressing three or more enzymes that aid in opening the β ring of cholesterol. The disclosed compositions and methods may be useful in lowering cholesterol levels in a subject in need thereof. In some embodiments, the subject may have a genetic predisposition to atherosclerosis.
FILED Wednesday, March 01, 2023
APPL NO 18/115846
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class

Peptides
C07K 2319/43 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 9/001 (20130101)
C12N 15/52 (20130101)
C12N 15/62 (20130101)
C12N 2710/16141 (20130101)
C12N 2820/005 (20130101)
C12N 2820/60 (20130101)

Enzymes
C12Y 101/01051 (20130101)
C12Y 101/01145 (20130101)
C12Y 103/01021 (20130101)
C12Y 103/99004 (20130101)
C12Y 106/02004 (20130101)
C12Y 114/15 (20130101)
C12Y 114/15006 (20130101)
C12Y 118/01002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263831 Hill et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) FRED HUTCHINSON CANCER CENTER (Seattle, Washington)
ASSIGNEE(S) FRED HUTCHINSON CANCER CENTER (Seattle, Washington)
INVENTOR(S) Geoffrey Hill (Seattle, Washington);  Simone Minnie (Seattle, Washington)
ABSTRACT Methods for treating malignancies including multiple myeloma (MM), methods for expanding immune cells, methods for characterizing and enhancing anti-tumor functions of immune cells, and methods for characterizing immune cell responses to agonist immunotherapies including decoy-resistant IL-18 (DR-18) therapies. The methods include administering a composition to enrich for a precursor exhausted population with stem-like properties and the ability for self-renewal (TPEX cells), which is crucial for sustaining an immune response to chronic infection and tumors TPEX cells and/or TOX+TEFF cells
FILED Thursday, February 23, 2023
APPL NO 18/173485
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class
A61K 38/20 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263832 Park et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Shin-Young Park (Waltham, Massachusetts);  Leslie E. Silberstein (Miami, Florida);  Jina Ryu (Seoul, South Korea);  Min Liu (Brighton, Massachusetts)
ABSTRACT Provided herein, in some aspects, are compositions comprising vasoocclusion-inhibiting agents encapsulated in RBCs and uses thereof for treating blood vessel occlusion (e.g., in Sickle Cell Disease).
FILED Friday, July 09, 2021
APPL NO 18/015209
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/506 (20130101)
A61K 31/4439 (20130101)
A61K 31/4709 (20130101)
A61K 35/18 (20130101) Original (OR) Class
A61K 38/58 (20130101)
A61K 38/482 (20130101)
A61K 39/3955 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/02 (20180101)

Enzymes
C12Y 304/21068 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263855 Wickline et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of South Florida (Tampa, Florida);  Washington University (St. Louis, Missouri)
ASSIGNEE(S)
INVENTOR(S) Samuel A. Wickline (Temple Terrace, Florida);  Hua Pan (Tampa, Florida);  Christine Thien-Nga Pham (St. Louis, Missouri);  Huimin Yan (St. Louis, Missouri)
ABSTRACT The present disclosure relates to nanoparticles and methods for polynucleotide transfection.
FILED Friday, November 18, 2022
APPL NO 18/056823
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/51 (20130101)
A61K 31/7105 (20130101)
A61K 38/16 (20130101) Original (OR) Class
A61K 47/64 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)
A61P 19/02 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263861 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S)
INVENTOR(S) Jennifer Yunyan Zhang (Durham, North Carolina);  Jessica Shannon (Durham, North Carolina)
ABSTRACT Provided herein are methods for promoting hair growth in a subject involving providing TSLP to the subject. Further provided herein are methods for preventing hair loss in a subject, including chemotherapy-induced hair loss, by inhibiting TSLP in the subject.
FILED Thursday, February 23, 2023
APPL NO 18/173358
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0021 (20130101)
A61K 38/20 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 17/14 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263872 Pineda et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Envisagenics, Inc. (New York, New York)
ASSIGNEE(S) Envisagenics, Inc. (New York, New York);  Envisagenics, Inc. (New York, New York)
INVENTOR(S) Maria Luisa Pineda (New York, New York);  Martin Akerman (Huntington, New York);  Gayatri Arun (Huntington Station, New York);  Naomi Yudanin (New York, New York);  Priyanka Dhingra (Jersey City, New Jersey)
ABSTRACT Provided herein are systems and methods for identifying alternative splicing derived cell surface antigens. Also provided are methods and compositions for using the identified cell surface antigens. Further provided are methods, compositions, and systems for diagnosing diseases in a subject using the identified cell surface antigens or treating diseases using the same.
FILED Friday, August 27, 2021
APPL NO 18/023674
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101) Original (OR) Class
A61K 39/4611 (20230501)
A61K 39/4631 (20230501)
A61K 39/4632 (20230501)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/4748 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5011 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 15/00 (20190201)
G16B 40/20 (20190201)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/50 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263875 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S)
INVENTOR(S) Szu-Wen Wang (Irvine, California);  Nicholas Molino (Philadelphia, Pennsylvania);  Medea Neek (Irvine, California);  Edward L. Nelson (Irvine, California);  Jo Anne Tucker (Irvine, California)
ABSTRACT Cancer-testis antigens were simultaneously packaged with CpG adjuvant and incorporated into an E2 nanoparticle platform to increase cancer vaccine efficacy. Also described herein is a combination of checkpoint blockade therapy and the nanoparticle vaccine platform to deliver cancer antigens with adjuvant for treatment of tumors and prevention of future tumors. The nanoparticle vaccine platform includes a protein capsule to which are attached adjuvants in the internal hollow cavity and cancer epitopes to the surface. Whereas single-therapies only increase survival, the combined therapy can both increase survival time as well as prevent tumor development in pre-existing tumor conditions by increasing tumor antigen-specific responses (via the nanoparticle vaccines) while simultaneously blocking checkpoints to remove immune suppression (via immune checkpoint inhibition). Furthermore, tumor rechallenge studies show evidence of T cell memory which can prevent tumor development in some individuals.
FILED Friday, September 23, 2022
APPL NO 17/934996
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/001154 (20180801)
A61K 39/001184 (20180801) Original (OR) Class
A61K 2039/55555 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/04 (20180101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263883 Elledge et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Brigham and Women`s Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Stephen J. Elledge (Brookline, Massachusetts);  Ellen Shrock (Boston, Massachusetts);  Eric Fujimura (Boston, Massachusetts)
ABSTRACT Peptide epitopes identified in subjects infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and methods of use thereof for diagnosing, determining prognosis, and treating Coronavirus Disease 2019 (COVID-19), and developing prophylactic or therapeutic vaccines against SARS-CoV-2.
FILED Thursday, July 08, 2021
APPL NO 18/014947
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/215 (20130101) Original (OR) Class
A61K 49/0004 (20130101)

Peptides
C07K 16/10 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101)
G01N 2333/165 (20130101)
G01N 2469/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263890 Myo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Tessa Therapeutics Ltd. (Singapore, Singapore);  The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) Tessa Therapeutics Ltd. (Singapore, Singapore);  The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Aung Myo (Singapore, Singapore);  Ivan David Horak (Singapore, Singapore);  Jonathan Serody (Chapel Hill, North Carolina);  Gianpietro Dotti (Chapel Hill, North Carolina);  Barbara Savoldo (Chapel Hill, North Carolina)
ABSTRACT Methods for treating a CD30-positive cancer in a subject are disclosed, wherein the methods comprise administering a lymphodepleting chemotherapy and CD30-specific chimeric antigen receptor (CAR)-expressing cells.
FILED Friday, June 04, 2021
APPL NO 18/007709
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4184 (20130101)
A61K 31/7076 (20130101)
A61K 39/4611 (20230501)
A61K 39/4622 (20230501)
A61K 39/4631 (20230501)
A61K 39/464411 (20230501)
A61K 39/464417 (20230501) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/7051 (20130101)
C07K 14/70521 (20130101)
C07K 14/70578 (20130101)
C07K 2317/53 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263891 CHALASANI et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Salk Institute for Biological Studies (La Jolla, California)
ASSIGNEE(S) Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S) Sreekanth CHALASANI (La Jolla, California);  Yusuf TUFAIL (La Jolla, California);  Jose Mendoza LOPEZ (La Jolla, California);  Marc Duque RAMIREZ (La Jolla, California);  Uri MAGARAM (La Jolla, California);  Corinne LEE-KUBLI (La Jolla, California);  Eric Warren EDSINGER (La Jolla, California)
ABSTRACT Described herein are compositions featuring TRPA1 polypeptides and polynucleotides, methods for expressing such polypeptides and polynucleotides in a cell type of interest, and methods for inducing the activation of the TRPA1 polypeptide in neurons and other cell types using ultrasound.
FILED Thursday, July 15, 2021
APPL NO 18/016251
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/177 (20130101)
A61K 41/0028 (20130101) Original (OR) Class
A61K 48/0083 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263943 Myung et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California);  The United States Government as represented by the Department of Veterans Affairs (NW Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) David Myung (Saratoga, California);  Fang Chen (Stanford, California);  Gabriella Fernandes-Cunha (Palo Alto, California);  Sarah Hull (Stanford, California);  Sarah Heilshorn (Mountain View, California);  Christopher Lindsay (San Mateo, California);  Christopher Madl (Los Altos, California);  Hyun Jong Lee (Gyeonggi-do, South Korea)
ABSTRACT Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined hydrogel structure in situ, including interpenetrating (IPN) and semi-IPN hydrogels.
FILED Thursday, April 29, 2021
APPL NO 17/997097
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/142 (20130101)
A61F 2210/0085 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/26 (20130101)
A61L 27/52 (20130101) Original (OR) Class
A61L 2400/06 (20130101)
A61L 2430/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264043 Wu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) Xiaodong Wu (Iowa City, Iowa);  Weiyu Xu (Iowa City, Iowa);  Jirong Yi (Iowa City, Iowa)
ABSTRACT A method for needle position optimization for prostate brachytherapy for use with a radiation delivery device configured to use a plurality of needles inserted into a prostate of a patient includes obtaining imagery of the prostate of the patient, generating a needle pool for prostate brachytherapy treatment of the patient based on the imagery of the prostate of the patient, and determining at a computing device an optimum prostate brachytherapy treatment plan for the patient by iteratively removing needles from the needle pool by forming and computationally solving a convex optimization problem wherein the convex optimization problem uses a quadratic dosimetric penalty function, dwell time regularization by total variation, and block sparsity regularization term.
FILED Friday, February 17, 2023
APPL NO 18/170784
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1014 (20130101) Original (OR) Class
A61N 5/1039 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265068 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Tennessee Research Foundation (Memphis, Tennessee)
ASSIGNEE(S) University of Tennessee Research Foundation (Memphis, Tennessee)
INVENTOR(S) Wei Li (Germantown, Tennessee);  Julio Cordero-Morales (Germantown, Tennessee);  Jianxiong Jiang (Memphis, Tennessee);  Zhongzhi Wu (Collierville, Tennessee);  Francesca Liao (Memphis, Tennessee);  Catherine Kaczorowski (Memphis, Tennessee)
ABSTRACT Provided herein are compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat diseases or disorders associated with TRPC3 activity.
FILED Wednesday, April 12, 2023
APPL NO 18/299562
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/08 (20180101)

Heterocyclic Compounds
C07D 401/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265070 Buhrlage et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Sara Buhrlage (Somerville, Massachusetts);  Kenneth C. Anderson (Wellesley, Massachusetts);  Dharminder Chauhan (Natick, Massachusetts);  Sirano Dhe-Paganon (Holliston, Massachusetts);  Xiaoxi Liu (Burlington, Massachusetts);  Hyuk-Soo Seo (Boston, Massachusetts)
ABSTRACT The present disclosure relates to inhibitors of USP7 useful in the treatment of cancers, and other USP7 mediated diseases, having the Formula: wherein R1, R2, R3, R4, R5, R6, and n are described herein.
FILED Friday, September 02, 2022
APPL NO 17/902512
CURRENT CPC
Heterocyclic Compounds
C07D 401/06 (20130101)
C07D 401/14 (20130101) Original (OR) Class
C07D 403/06 (20130101)
C07D 413/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265149 VEISEH et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) William Marsh Rice University (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Omid VEISEH (Houston, Texas);  David ZHANG (Houston, Texas);  Sudip MUKHERJEE (Houston, Texas);  Maria RUOCCO (Houston, Texas);  Michael DOERFERT (Houston, Texas);  Amanda NASH (Houston, Texas);  Samira AGHLARA-FOTOVAT (Houston, Texas)
ABSTRACT The present disclosure relates to implantable constructs (encapsulated cells) designed to deliver antigenic therapeutic reagents, such as IL-2.
FILED Wednesday, October 19, 2022
APPL NO 18/047856
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/55 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0012 (20130101)
C12N 5/0621 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265165 JIN
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S)
INVENTOR(S) Moonsoo JIN (New York, New York)
ABSTRACT The present invention is directed to transduced T cells expressing at least 100,000 molecules of human somatostatin receptor 2 (SSTR2), which improves PET/CT imaging sensitivity. The present invention is also directed to transduced T cells expressing SSTR2 and chimeric antigen receptor (CAR). In one embodiment, the CAR is specific to human ICAM-1 and the CAR comprises a binding domain that is scFv of anti-human ICAM-1, or an I domain of the αL subunit of human lymphocyte function-associated antigen-1. In another embodiment, the CAR is specific to human CD19, and the CAR comprises a binding domain that is scFv of anti-human CD19. The present invention is further directed to using the above transduced T cells for monitoring T cell distribution in a patient by PET/CT imaging and/or treating cancer.
FILED Tuesday, March 21, 2023
APPL NO 18/187268
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 38/1796 (20130101)
A61K 39/0011 (20130101)
A61K 39/001166 (20180801)
A61K 51/083 (20130101)
A61K 51/088 (20130101)
A61K 2039/54 (20130101)
A61K 2039/515 (20130101)

Peptides
C07K 14/723 (20130101) Original (OR) Class
C07K 14/7051 (20130101)
C07K 14/70521 (20130101)
C07K 14/70553 (20130101)
C07K 2319/03 (20130101)
C07K 2319/74 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265169 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  Korea (Center for Disease Control and Prevention) (Chungcheongbuk-do, South Korea)
ASSIGNEE(S)
INVENTOR(S) Hansaem Lee (Chungcheongbuk-do, South Korea);  Janghoon Choi (Chungcheongbuk-do, South Korea);  Sungsoon Kim (Chungcheongbuk-do, South Korea);  Lingshu Wang (Bethesda, Maryland);  Barney Graham (Bethesda, Maryland);  John R Mascola (Bethesda, Maryland)
ABSTRACT The present invention relates to monoclonal antibodies for a spike protein of the Middle East respiratory syndrome coronavirus (MERS-CoV), and a use thereof. Particularly, monoclonal antibodies 77-A5, 77-A6, 90-A3, 90-A9, 90-B2, 90-B7, 90-C4, 90-E5, 90-E6, 90-F1 and 90-F2 according to the present invention have excellent attachment force with respect to a full-length spike protein of MERS-CoV and the S1 domain of the protein, and, of the monoclonal antibodies, the monoclonal antibodies 90-F1, 90-E5, 90-E6, 90-F2, 77-A5 and 77-A6 have excellent attachment force with respect to an RBD antigen of MERS-CoV. Also, the antibodies 77-A5, 77-A6, 90-E5, 90-E6, 90-F1 and 90-F2 exhibit neutralizing capacity with respect to a MERS pseudovirus and MERS-CoV, and the antibodies 90-B2 and 90-B7 exhibit neutralizing capacity only with respect to MERS-CoV. Further, the monoclonal antibodies have a particular monomeric form, and have excellent stability and thus may be useful for treating or diagnosing MERS.
FILED Sunday, September 25, 2022
APPL NO 17/952308
CURRENT CPC
Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101)
G01N 2333/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265180 GREENE et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S)
INVENTOR(S) Mark I. GREENE (Penn Valley, Pennsylvania);  Zheng CAI (Wynnewood, Pennsylvania);  Zhiqiang ZHU (Philadelphia, Pennsylvania);  Douglas B. CINES (Wynnewood, Pennsylvania)
ABSTRACT Provided herein are isolated antibodies or antibody fragments thereof that immunospecifically bind to platelet factor 4 (PF4). In some embodiments the isolated antibodies or antigen-binding fragments thereof comprise a light chain CDR and framework region comprising SEQ ID NO: 4 and a heavy chain CDR and framework region comprising SEQ ID NO: 10. Also provided herein are methods for treating heparin-induced thrombocytopenia (HIT) and methods for reducing the likelihood that subject will become afflicted with HIT. Further disclosed are uses of the isolated antibodies or antibody fragments in the treatment of HIT or the manufacture of compositions for the treatment of HIT.
FILED Tuesday, November 29, 2022
APPL NO 18/071057
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/702 (20130101)
A61K 31/727 (20130101)
A61K 38/00 (20130101)

Peptides
C07K 16/24 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265206 WELLS et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) James A. WELLS (San Francisco, California);  Alexander J. MARTINKO (San Francisco, California);  Juan E. DIAZ (San Francisco, California);  Michael J. HORNSBY (San Francisco, California)
ABSTRACT The disclosure is related to antibodies and antibody fragments that specifically bind the CUB domain-containing protein 1 (CDCP1) and their methods and uses in treating and detecting cancers.
FILED Friday, March 10, 2023
APPL NO 18/182277
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/6803 (20170801)
A61K 47/6849 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2809 (20130101)
C07K 16/2896 (20130101) Original (OR) Class
C07K 2317/31 (20130101)
C07K 2317/92 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57492 (20130101)
G01N 2333/70596 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265214 Quijano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut);  GENNAO BIO, INC. (Pennington, New Jersey)
ASSIGNEE(S)
INVENTOR(S) Elias Quijano (New Haven, Connecticut);  Peter Glazer (New Haven, Connecticut);  Bruce C. Turner (Bryn Mawr, Pennsylvania);  Audrey Turchick (Chelmsford, Massachusetts);  W. Mark Saltzman (New Haven, Connecticut)
ABSTRACT Compositions and methods of use thereof for delivering nucleic acid cargo into cells are provided. The compositions typically include (a) a 3E10 monoclonal antibody or an antigen binding, cell-penetrating fragment thereof; a monovalent, divalent, or multivalent single chain variable fragment (scFv); or a diabody; or humanized form or variant thereof, and (b) a nucleic acid cargo including, for example, a nucleic acid encoding a polypeptide, a functional nucleic acid, a nucleic acid encoding a functional nucleic acid, or a combination thereof. Elements (a) and (b) are typically non-covalently linked to form a complex.
FILED Tuesday, August 31, 2021
APPL NO 18/043534
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/40 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/117 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265382 Young, JR. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S)
INVENTOR(S) Samuel M. Young, JR. (Iowa City, Iowa);  Stacia Phillips (Iowa City, Iowa)
ABSTRACT Methods to produce helper dependent adenovirus, and a cell, vector and kit useful in that regard, are provided.
FILED Thursday, November 10, 2022
APPL NO 17/984575
CURRENT CPC
Peptides
C07K 14/075 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0602 (20130101) Original (OR) Class
C12N 15/86 (20130101)
C12N 2710/10041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265383 Wilson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Wilson Wolf Manufacturing (New Brighton, Minnesota)
ASSIGNEE(S)
INVENTOR(S) John R. Wilson (New Brighton, Minnesota)
ABSTRACT This invention relates to methods and devices that improve cell culture efficiency. They include the use of gas permeable culture compartments that reduce the use of space while maintaining uniform culture conditions, and are more suitable for automated liquid handling. They include the integration of gas permeable materials into the traditional multiple shelf format to resolve the problem of non-uniform culture conditions. They include culture devices that use surfaces comprised of gas permeable, plasma charged silicone and can integrate traditional attachment surfaces, such as those comprised of traditional tissue culture treated polystyrene. They include culture devices that integrate gas permeable, liquid permeable membranes. A variety of benefits accrue, including more optimal culture conditions during scale up and more efficient use of inventory space, incubator space, and disposal space. Furthermore, labor and contamination risk are reduced.
FILED Friday, April 07, 2023
APPL NO 18/132235
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/08 (20130101)
C12M 23/24 (20130101)
C12M 23/34 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0602 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265387 Gros et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Alena Gros (Barcelona, Spain);  Steven A. Rosenberg (Potomac, Maryland)
ABSTRACT Methods of obtaining a cell population enriched for tumor-reactive T cells, the method comprising: (a) obtaining a bulk population of T cells from a tumor sample; (b) specifically selecting CD8+ T cells that express any one or more of TIM-3, LAG-3, 4-1BB, and PD-1 from the bulk population; and (c) separating the cells selected in (b) from unselected cells to obtain a cell population enriched for tumor-reactive T cells are disclosed. Related methods of administering a cell population enriched for tumor-reactive T cells to a mammal, methods of obtaining a pharmaceutical composition comprising a cell population enriched for tumor-reactive T cells, and isolated or purified cell populations are also disclosed.
FILED Friday, January 06, 2023
APPL NO 18/093902
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 39/0011 (20130101)
A61K 2039/5158 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101) Original (OR) Class
C12N 5/0638 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265393 SABAAWY et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Rutgers, the State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S)
INVENTOR(S) Hatim SABAAWY (Neshanic Station, New Jersey);  Fredrick E. WONDISFORD (New Brunswick, New Jersey)
ABSTRACT Liver metabolism studies are limited by the inability to expand primary hepatocytes in vitro while maintaining their metabolic functions. Human hepatic three dimensional organoids have been established for use in these studies, but hepatic organoids from adult donors had impaired expansion. Methods of achieving expansion of adult donor-derived hepatic organoids (HepAOs) and HepG2 cells (HepGOs) from single cells in organoid cultures using combinations of growth factors and small molecules are described, with assessment of expansion dynamics, gluconeogenic and HNF4α expression, and albumin secretion. The invention discloses conditions including limiting A8301 and incorporating FSK and OSM to allow the expansion of HepAOs from adult donors and HepGOs with gluconeogenic competence. These models increase the repertoire of human hepatic cellular tools available for use in liver metabolic assays.
FILED Monday, September 26, 2022
APPL NO 17/935135
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0671 (20130101) Original (OR) Class
C12N 2500/30 (20130101)
C12N 2500/90 (20130101)
C12N 2501/155 (20130101)
C12N 2501/237 (20130101)
C12N 2501/727 (20130101)
C12N 2506/14 (20130101)
C12N 2506/30 (20130101)
C12N 2513/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265405 CHAUHAN et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) VIKASH PAL SINGH CHAUHAN (CAMBRIDGE, Massachusetts);  PHILLIP A. SHARP (NEWTON, Massachusetts);  ROBERT LANGER (NEWTON, Massachusetts)
ABSTRACT The present disclosure provides a method of editing a genome in a cell including exposing the cell to an engineered Cas nuclease comprising one or more mutations within the DNA binding cleft of the Cas nuclease, wherein exposure to the engineered Cas nuclease decreases, inhibits, or prevents non-homologous end joining (NHEJ) in the cell, and wherein exposure to the engineered Cas nuclease increases one or more homology-driven repair pathways within the cell. The mutant Cas nuclease is also disclosed herein.
FILED Wednesday, December 21, 2022
APPL NO 18/069387
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265420 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Feng Zhang (Cambridge, Massachusetts);  Jonathan Strecker (Cambridge, Massachusetts);  Alim Ladha (Cambridge, Massachusetts);  Guilhem Faure (Cambridge, Massachusetts)
ABSTRACT The present application provides systems, methods and compositions used for targeted gene modification, targeted insertion, perturbation of gene transcripts, nucleic acid editing. Novel nucleic acid targeting systems comprise components of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems and transposable elements.
FILED Friday, June 18, 2021
APPL NO 17/928355
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101) Original (OR) Class
C12N 15/63 (20130101)
C12N 15/90 (20130101)
C12N 2310/20 (20170501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265422 Farzan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) THE SCRIPPS RESEARCH INSTITUTE (, None)
ASSIGNEE(S)
INVENTOR(S) Michael Farzan (Juno Beach, Florida);  Guocai Zhong (Jupiter, Florida);  Haiming Wang (Jupiter, Florida)
ABSTRACT The present invention provides novel RNA switches that are based on modified hammerhead ribozymes with improved activities. Also provided are expression vectors and related expression systems for regulating transgene expression in various clinical or industrial applications.
FILED Wednesday, October 14, 2020
APPL NO 17/768896
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 15/635 (20130101)
C12N 2310/121 (20130101)
C12N 2310/128 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265425 GARG
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S)
INVENTOR(S) Angad GARG (New York, New York)
ABSTRACT The present disclosure provides gene expression systems and methods for producing and/or overexpressing heterologous polypeptides in eukaryotic cells. Kits for practicing the methods are also disclosed.
FILED Thursday, July 01, 2021
APPL NO 18/004028
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/81 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2320/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265432 RONAI et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California)
ASSIGNEE(S)
INVENTOR(S) Ze'ev A. RONAI (Fallbrook, California);  Ali KHATEB (San Diego, California)
ABSTRACT The present disclosure provides compositions and methods for treating acute myeloid leukemia (AML) using a histone deacetylase (HDAC) inhibitor alone or incombination with a RING finger protein 5 (RNF5) inhibitor and/or a retinoblastoma binding protein 4 (RBBP4) inhibitor. Moreover, RNF5 and/or RBBP4 expression or protein levels in a patient can be measured and used to inform individualized treatment options and dosing regiments. For example, AML patients with lower levels of either RNF5 or RBBP4 may be stratified and treated with one or more HDAC inhibitors leading to improved therapeutic results.
FILED Thursday, October 20, 2022
APPL NO 18/048382
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/69 (20130101)
A61K 31/167 (20130101)
A61K 31/365 (20130101)
A61K 31/427 (20130101)
A61K 31/506 (20130101)
A61K 31/519 (20130101)
A61K 31/4178 (20130101)
A61K 31/7072 (20130101)
A61K 38/15 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/02 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1135 (20130101) Original (OR) Class
C12N 2310/531 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6851 (20130101)
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57426 (20130101)
G01N 2440/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265440 Gomez-Ospina et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Natalia Gomez-Ospina (Stanford, California);  Matthew H. Porteus (Stanford, California);  Samantha Glynne Scharenberg (Stanford, California);  Alvaro Amorin (Stanford, California)
ABSTRACT The present disclosure provides methods and compositions for treating lysosomal storage disorders in subjects, comprising genetically modifying cells from the subjects ex vivo by integrating therapeutic transgenes into the CCR5 locus.
FILED Friday, June 25, 2021
APPL NO 18/010773
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0647 (20130101)
C12N 9/24 (20130101)
C12N 15/86 (20130101)
C12N 15/1138 (20130101) Original (OR) Class
C12N 2310/321 (20130101)
C12N 2510/00 (20130101)

Enzymes
C12Y 302/01076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265442 Djuranovic et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S)
INVENTOR(S) Sergej Djuranovic (St. Louis, Missouri);  Rachel Green (Baltimore, Maryland)
ABSTRACT The present disclosure relates to modulation of protein expression.
FILED Monday, March 13, 2023
APPL NO 18/182948
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/64 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265453 Xue et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Baylor College of Medicine (Houston, Texas)
ASSIGNEE(S)
INVENTOR(S) Mingshan Xue (Houston, Texas);  Wu Chen (Houston, Texas)
ABSTRACT The disclosure concerns compositions and methods for treatment of encephalopathies, including encephalopathies caused by, or associated with, and STXBP1 haploinsufficiency or mutation. Compositions and methods provided herein encompass AAV particles that induce expression of STXBP1, including inducing the expression of STXBP1 in central and/or peripheral nervous system cells.
FILED Thursday, July 08, 2021
APPL NO 18/004194
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)

Peptides
C07K 14/47 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101) Original (OR) Class
C12N 2750/14143 (20130101)
C12N 2750/14171 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265455 Boye et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Shannon E. Boye (Gainesville, Florida);  Sanford L. Boye (Gainesville, Florida)
ABSTRACT The present disclosure provides for improved recombinant AAV therapies for the treatment of X-linked retinoschisis (XLRS). These therapies are designed for administration to subjects, such as human subjects, including humans diagnosed with or suffering from XLRS.
FILED Wednesday, July 28, 2021
APPL NO 18/017726
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 48/0058 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)

Peptides
C07K 14/005 (20130101)
C07K 14/47 (20130101)
C07K 14/475 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265487 Seelig et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Georg Seelig (Seattle, Washington);  Richard Muscat (Seattle, Washington);  Alexander B. Rosenberg (Seattle, Washington)
ABSTRACT Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
FILED Thursday, March 23, 2023
APPL NO 18/188504
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101) Original (OR) Class
C12Q 1/6855 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265508 Vizcardo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Raul E. Vizcardo (Foster City, California);  SM Rafiqul Islam (Bethesda, Maryland);  Naritaka Tamaoki (South San Francisco, California);  Takuya Maeda (Bethesda, Maryland);  Nicholas P. Restifo (Chevy Chase, Maryland)
ABSTRACT Disclosed are methods for reprogramming cancer-reactive T cells into iPSC cells as well as methods utilizing such cells for the identification of cancer-antigen specific TCRs and the treatment of cancer.
FILED Friday, August 20, 2021
APPL NO 18/020823
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0696 (20130101)
C12N 2501/51 (20130101)
C12N 2501/515 (20130101)
C12N 2502/30 (20130101)
C12N 2506/11 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6881 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265516 GARCIA et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) UNIVERSITY OF ARIZONA, ARIZONA BOARD OF REGENTS (Tucson, Arizona)
ASSIGNEE(S)
INVENTOR(S) Joe G.N. GARCIA (Tucson, Arizona);  Mohamed n. AHMED (Tucson, Arizona)
ABSTRACT A method of identifying single nucleotide polymorphisms (SNPs) within the NAMPT promoter that are associated with an inflammatory condition, such as cardiac ischemia, traumatic brain injury, cancer, chorioamnionitis, nonalcoholic steatohepatitis (NASH), or renal fibrosis. Also provided are methods of diagnosing and treating such inflammatory condition in a subject.
FILED Friday, August 06, 2021
APPL NO 18/040976
CURRENT CPC
Peptides
C07K 16/40 (20130101)
C07K 2317/565 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266211 D'SILVA et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland);  THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S)
INVENTOR(S) Joseph D'SILVA (Hillsboro, Oregon);  Robert H. AUSTIN (Princeton, New Jersey);  Curt CIVIN (Baltimore, Maryland);  James C. STURM (Princeton, New Jersey)
ABSTRACT Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
FILED Tuesday, September 20, 2022
APPL NO 17/948541
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/14 (20130101)
A61K 35/28 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502753 (20130101)
B01L 3/502761 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2300/1894 (20130101)
B01L 2400/086 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/34 (20130101) Original (OR) Class
G01N 15/1404 (20130101)
G01N 33/5094 (20130101)
G01N 2015/008 (20130101)
G01N 2333/70596 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266214 COON et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Joshua COON (Middleton, Wisconsin);  Michael WESTPHALL (Fitchburg, Wisconsin)
ABSTRACT The present invention provides methods for controllably forming a layer of amorphous ice and other amorphous solids on a substrate, and also provides cryo-electron microscopy (cryo-EM) sample preparation methods and systems that utilize in vacuo formation of amorphous ice and other solids. Formation of the amorphous solid layer can be independent of the deposition of sample molecules to be analyzed using electron microscopy, and allows for the generation of a uniformly thick layer. Optionally, mass spectrometry instruments are used to generate and purify molecules deposited on the generated amorphous solid layer. The techniques and systems described herein can deliver near ideal cryo-EM sample preparation to greatly increase resolution, sensitivity, scope, and throughput of cryo-EM protein imaging, and therefore greatly impact the field of structural biology.
FILED Thursday, November 10, 2022
APPL NO 17/984934
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/36 (20130101)
G01N 1/42 (20130101) Original (OR) Class
G01N 15/1468 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 37/26 (20130101)
H01J 37/28 (20130101)
H01J 49/164 (20130101)
H01J 49/165 (20130101)
H01J 2237/31745 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266270 GURKAN et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S)
INVENTOR(S) UMUT GURKAN (Shaker Heights, Ohio);  MICHAEL HINCZEWSKI (Cleveland, Ohio);  SHAMREEN IRAM (Cleveland, Ohio);  RAN AN (Shaker Heights, Ohio)
ABSTRACT An example system includes one or more non-transitory machine-readable media and one or more processors. The non-transitory machine-readable media is configured to store data and instructions, in which the data includes image data having a plurality of image frames of an electrophoresis process performed on a sample over a time interval. The sample contains at least one analyte. The one or more processors are configured to access the data and execute the instructions, in which the instructions programmed to perform a method. The method can include determining values of pixels within a region of interest (ROI) of respective image frames in the time interval. The method can also include analyzing the determined pixel values for at least some of the respective image frames. The method can also include estimating a quantity of the at least one analyte in the sample based on the analysis of the pixel values.
FILED Monday, June 28, 2021
APPL NO 18/012951
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44721 (20130101) Original (OR) Class
G01N 33/721 (20130101)
G01N 33/726 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266304 SCHULTZ-CHERRY et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee)
ASSIGNEE(S)
INVENTOR(S) Stacey SCHULTZ-CHERRY (Memphis, Tennessee);  Victoria MELIOPOULOS (Memphis, Tennessee);  Rebekah HONCE (Memphis, Tennessee)
ABSTRACT A method for establishing an obese ferret model by feeding a ferret with a diet having at least 25% of carbohydrate content for a period of time to provide the obese ferret model is disclosed as is a method of using said model to screen a substance for treating a respiratory infection.
FILED Monday, July 12, 2021
APPL NO 18/005105
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5088 (20130101) Original (OR) Class
G01N 2333/11 (20130101)
G01N 2333/46 (20130101)
G01N 2333/165 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266306 Kumar et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The U.S.A., as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland)
ASSIGNEE(S) The U.S.A., as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland)
INVENTOR(S) Sanjai Kumar (Potomac, Maryland);  Nitin Verma (Germantown, Maryland);  Ankit Puri (Rockville, Maryland)
ABSTRACT Identification of immunodominant Babesia microti antigens using genome-wide immunoscreening is described. Candidate antigens were screened against sera from patients with clinical babesiosis. Also described are diagnostic assays with high sensitivity and specificity for detecting B. microti-specific antibodies in patient samples using the identified immunodominant antigens.
FILED Tuesday, March 21, 2023
APPL NO 18/187241
CURRENT CPC
Peptides
C07K 14/44 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1096 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54306 (20130101) Original (OR) Class
G01N 33/56905 (20130101)
G01N 2469/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266315 James et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma)
ASSIGNEE(S) Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma);  Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma)
INVENTOR(S) Judith A. James (Oklahoma City, Oklahoma);  Melissa E. Munroe (Oklahoma City, Oklahoma)
ABSTRACT The present invention involves the identification of biomarkers that are predictive of impeding systemic lupus erythematosus (SLE) disease flare. Methods for treating patients so identified are also provided.
FILED Friday, September 16, 2022
APPL NO 17/946756
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/564 (20130101) Original (OR) Class
G01N 33/6863 (20130101)
G01N 2800/52 (20130101)
G01N 2800/104 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266321 Dar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
NIH Office of the Director (NIHOD)
APPLICANT(S) Icahn School of Medicine at Mount Sinai (New York, New York)
ASSIGNEE(S)
INVENTOR(S) Arvin Dar (New York, New York);  Zaigham M. Khan (New York, New York);  William Michael Marsiglia (New York, New York)
ABSTRACT A detectable probe comprising a moiety, which is an ATP non-competitive inhibitor of mitogen-activated protein kinase (MEK), inter alia, human MEK (MEK1 or MEK2) having the properties: (i) allosterically binds an inhibitor pocket formed at an interaction interface between human MEK (MEK1 or MEK2) and human Kinase Suppressor of Ras (KSR1 or KSR2 orBRAF) adjacent to ATP in a physiological complex between MEK and KSR (or BRAF), forming an inhibitor-inhibitor pocket complex; (ii) is an ATP non-competitive kinase inhibitor; (iii) a structure such that when bound to the inhibitor-inhibitor pocket complex, the complex comprises the structural elements: (a) at least one moiety of the inhibitor engaging A825 of KSR1, or P878 of KSR2; or R662 of BRAF (b) at least one moiety engaging R234 of MEK, wherein where R234 is within 5 A from any atoms of KSR1 or KSR2 or BRAF is disclosed. The probe further comprises a detectable label conjugated directly or through a linker to the inhibitor moiety.
FILED Friday, June 25, 2021
APPL NO 18/002812
CURRENT CPC
Heterocyclic Compounds
C07D 471/04 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/542 (20130101)
G01N 33/573 (20130101) Original (OR) Class
G01N 33/5011 (20130101)
G01N 2333/912 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266329 LYDEN et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S)
INVENTOR(S) David C. LYDEN (Old Chatham, New York);  Haiying ZHANG (New York, New York)
ABSTRACT The present invention is directed to methods of diagnosing, prognosing, and managing treatment of cancer in a subject. These methods involve selecting a subject having cancer and obtaining, from the selected subject, a population of either exomeres having a diameter less than 50 nm, small exosomes having a diameter of 60-80 nm, or large exosomes having a diameter of 90-120 nm. The exomeres, small exosomes, or large exosomes are recovered from the sample, and the exomeres, small exosomes, or large exosomes or portions thereof are contacted with one or more reagents suitable to detect: (1) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more proteins contained in said exomeres, small exosomes, or large exosomes, (2) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more N-glycans contained in said exomeres, small exosomes, or large exosomes, (3) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more lipids contained in said exomeres, small exosomes, or large exosomes, (4) the presence or absence of one or more genetic mutations in nucleic acid molecules associated with cancer and contained in said exomeres, small exosomes, or large exosomes, or (5) combinations thereof. Cancer is then diagnosed, prognosed, or treatment is modified based on this information.
FILED Thursday, December 15, 2022
APPL NO 18/082368
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/118 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/68 (20130101)
G01N 33/6893 (20130101)
G01N 33/57484 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266334 Mitra
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S)
INVENTOR(S) Robi D. Mitra (Fenton, Missouri)
ABSTRACT Methods are disclosed for identifying one or more proteins or polypeptides comprised by a sample. The methods comprise determining binding of each polypeptide with respect to each binding pool of a plurality of binding pools, wherein each binding pool comprises one or more probes which bind a structure comprised by a protein or polypeptide. In some aspects, polypeptides can be denatured and separated into individual polypeptide strands and immobilized on a solid support prior to determining binding of the binding pools. A protein, polypeptide or polypeptide strand can be identified by searching, in at least one database, for a protein or polypeptide sequence comprising binding pool targets either identical to or most similar to the binding pool targets comprised by the protein, polypeptide or polypeptide strand to be identified. Kits for identifying proteins, polypeptides and polypeptide strands are also disclosed.
FILED Monday, May 01, 2023
APPL NO 18/141767
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
G01N 33/6845 (20130101) Original (OR) Class
G01N 33/54306 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266417 Zhong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S)
INVENTOR(S) Zheng Zhong (Houston, Texas);  Christopher Michael Sandino (Menlo Park, California);  Shreyas S. Vasanawala (Stanford, California)
ABSTRACT A method for magnetic resonance imaging (MRI) performs a spoiled gradient-recalled (SPGR) MRI scan with an MRI scanner to produce MRI data; and reconstructs an MRI image from the MRI data; wherein performing the SPGR MRI scan comprises playing an interleaved-randomized spoiler (IRS) gradient after every M-th acquisition block, where M≥2, and where an absolute area of the IRS gradient of each IRS is randomized between zero and a maximum gradient area achievable on the MRI scanner.
FILED Friday, February 24, 2023
APPL NO 18/113805
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/561 (20130101) Original (OR) Class
G01R 33/5608 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266418 Kulam Najmudeen et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland);  The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
ASSIGNEE(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland);  The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
INVENTOR(S) Magdoom Mohamed Kulam Najmudeen (Bethesda, Maryland);  Peter J. Basser (Bethesda, Maryland);  Michal E. Komlosh (Bethesda, Maryland)
ABSTRACT Diffusion sensitizing gradient pulse pairs are prescribed in a manner to mitigate effects of concomitant gradient artifacts. Measured MR signals generated by applying a plurality of diffusion sensitizing gradient matrices are obtained and processed to determine a second order mean diffusion tensor and a fourth order covariance tensor. Quantities derived from these tensors are measured and mapped within an imaging volume which describe features of diffusion anisotropy and heterogeneity within each imaging voxel.
FILED Thursday, July 08, 2021
APPL NO 18/017150
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/022 (20130101)
G01R 33/246 (20130101)
G01R 33/56341 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266577 CUI
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
ASSIGNEE(S)
INVENTOR(S) Meng CUI (West Lafayette, Indiana)
ABSTRACT High speed laser scanning systems and methods are disclosed for imaging target samples. Embodiments of the laser scanning systems and methods include separating a laser beam into two or more different pathways and pulsing light along the two or more pathways. The different pathways intersect the surface of a moving mirror at different locations and light traveling in a pathway that is being approached by an edge of the moving reflective surface is turned off while light traveling in a different pathway that is farther from the edge of the moving reflective surface is turned on. Embodiments include reflective surfaces that form a rotating polygonal scanner. Further embodiments include recombining the two or more different pathways, focusing the laser light on a test sample, and imaging the light reflected from the test sample.
FILED Tuesday, February 21, 2023
APPL NO 18/172139
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/0048 (20130101) Original (OR) Class
G02B 26/124 (20130101)
G02B 26/125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267607 Sadri et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)
INVENTOR(S) Amir Reza Sadri (Cleveland Heights, Ohio);  Satish E. Viswanath (Beachwood, Ohio);  Thomas Desilvio (Lyndhurst, Ohio)
ABSTRACT In some embodiments, the present disclosure relates to a non-transitory computer-readable medium storing computer-executable instructions that, when executed, cause a processor to perform operations, including forming an imaging dataset having imaging data corresponding to one or more radiological images of a patient having a bowel disease; operating upon the imaging data with one or more convolutional neural network (CNN) segments configured to generate a plurality of CNN outputs, the one or more CNN segments respectively including a convolution layer configured to perform a convolution on the imaging data; and applying a wavelet network to the plurality of CNN outputs to generate a plurality of convolution wavelet network (CWN) outputs, the wavelet network being configured to decompose the plurality of CNN outputs according to a mother wavelet. A predictive signature associated with disease response or risk is constructed using the plurality of CWN outputs.
FILED Thursday, February 16, 2023
APPL NO 18/169935
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/7275 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/10116 (20130101)
G06T 2207/20064 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/20 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268029 Flusberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Pacific Biosciences of California, Inc. (Menlo Park, California)
ASSIGNEE(S)
INVENTOR(S) Benjamin Flusberg (Atlanta, Georgia);  Jonas Korlach (Camas, Washington);  Andrey Kislyuk (San Ramon, California);  Stephen Turner (Seattle, Washington);  Jon Sorenson (Alameda, California);  Kevin Travers (Menlo Park, California);  Cheryl Heiner (La Honda, California);  Austin B. Tomaney (Burlingame, California);  Patrick Marks (San Francisco, California);  Dale Webster (San Mateo, California);  Jeremiah Hanes (Menlo Park, California)
ABSTRACT Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
FILED Thursday, March 23, 2023
APPL NO 18/189075
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/32 (20130101)
A61F 2/30721 (20130101) Original (OR) Class
A61F 2/30767 (20130101)
A61F 2/30965 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268030 Flusberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Pacific Biosciences of California, Inc. (Menlo Park, California)
ASSIGNEE(S)
INVENTOR(S) Benjamin Flusberg (Atlanta, Georgia);  Jonas Korlach (Camas, Washington);  Andrey Kislyuk (San Ramon, California);  Stephen Turner (Seattle, Washington);  Jon Sorenson (Alameda, California);  Kevin Travers (Menlo Park, California);  Cheryl Heiner (La Honda, California);  Austin B. Tomaney (Burlingame, California);  Patrick Marks (San Francisco, California);  Dale Webster (San Mateo, California);  Jeremiah Hanes (Menlo Park, California)
ABSTRACT Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.
FILED Thursday, March 23, 2023
APPL NO 18/189084
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/32 (20130101)
A61F 2/30721 (20130101) Original (OR) Class
A61F 2/30767 (20130101)
A61F 2/30965 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268170 LI et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) West Virginia University (Morgantown, West Virginia)
ASSIGNEE(S)
INVENTOR(S) Peng LI (Morgantown, West Virginia);  Xiaojun LI (Morgantown, West Virginia);  Stephen J. VALENTINE (Morgantown, West Virginia);  Lisa HOLLAND (Morgantown, West Virginia)
ABSTRACT In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to a vibrating sharp edge spray ionization (VSSI) method suitable for coupling with a mass spectrometer, a VSSI method modified with a capillary suitable for use with continuous-flow separation methods such as liquid chromatography, and a VSSI method suitable for coupling with a capillary electrophoresis (CE) device in order to introduce the CE sample flow into a mass spectrometer. Also disclosed herein are devices for carrying out these methods and methods of making the same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
FILED Wednesday, February 22, 2023
APPL NO 18/172780
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/16 (20130101) Original (OR) Class
H01J 49/0031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 20230263164 Bowden et al.
FUNDED BY
National Science Foundation (NSF)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
ASSIGNEE(S) UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
INVENTOR(S) Ned B. Bowden (Iowa City, Iowa);  Justin M. CARTER (Iowa City, Iowa);  Eric M. BROWN (Iowa City, Iowa);  Nimesh RANASINGHE (Iowa City, Iowa);  Arjun PAUDEL (Iowa City, Iowa);  Erin E. IRISH (Iowa City, Iowa)
ABSTRACT The invention provides a compound of formula (I): wherein X, Y Z, R1, R2, and X+ have any of the values described in the specification. The compounds are useful to increase plant growth and/or to increase harvest yield.
FILED Monday, August 30, 2021
APPL NO 18/024034
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 57/12 (20130101) Original (OR) Class
A01N 57/16 (20130101)

Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations
A01P 21/00 (20210801)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/06 (20130101)
C07F 9/6578 (20130101)
C07F 9/657118 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263688 Young et al.
FUNDED BY
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)
INVENTOR(S) Aaron Young (Atlanta, Georgia);  Inseung Kang (Atlanta, Georgia);  Dawit Lee (Atlanta, Georgia)
ABSTRACT An exemplary embodiment of the present disclosure provides a knee exoskeleton comprising a first interface, a second interface, an actuator, and a controller. The first interface can be configured to interface with a portion of a leg of a user above a knee joint of the user. The second interface can be configured to interface with a portion of the leg of the user below the knee joint of the user. The actuator can be configured to generate a torque to cause a movement of at least one of the first and second interfaces. The controller can be configured to control the actuator to vary the magnitude of torque generated by the actuator.
FILED Thursday, July 01, 2021
APPL NO 18/003927
CURRENT CPC
Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 3/00 (20130101) Original (OR) Class
A61H 2003/007 (20130101)
A61H 2201/164 (20130101)
A61H 2201/165 (20130101)
A61H 2201/1628 (20130101)
A61H 2230/625 (20130101)
A61H 2230/655 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263729 Scott et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S)
INVENTOR(S) Evan A. Scott (Northfield, Illinois);  Guillermo A. Ameer (Chicago, Illinois);  Jacqueline A. Burke (Chicago, Illinois);  Sean D. Allen (Chicago, Illinois);  Sijia Yi (Evanston, Illinois)
ABSTRACT Provided herein are nanocarriers for delivery of immunosuppressive agents. In some embodiments, provided herein are nanocarriers comprising a core comprising a poly(ethylene glycol)-block-poly(propylene sulfide) copolymer and least one therapeutic agent. In some embodiments, the nanocarriers may further comprise a targeting ligand displayed on a surface of the nanocarrier. The at least one therapeutic agent may be an anti-inflammatory agent. The disclosed nanocarriers may be incorporated into pharmaceutical compositions for use in methods of treating an inflammatory condition or preventing transplantation rejection in a subject.
FILED Thursday, March 02, 2023
APPL NO 18/177694
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/1273 (20130101) Original (OR) Class
A61K 31/192 (20130101)
A61K 31/436 (20130101)
A61K 31/593 (20130101)
A61K 47/60 (20170801)
A61K 47/64 (20170801)
A61K 47/543 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)
A61P 41/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263918 Whitten et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) David G. Whitten (Albuquerque, New Mexico);  Kirk S. Schanze (Gainesville, Florida);  Linnea K. Ista (Albuquerque, New Mexico);  Patrick L. Donabedian (Gainesville, Florida);  Eva Yung Hua Chi (Albuquerque, New Mexico);  Florencia A. Monge (Albuquerque, New Mexico);  Alison Meredith Kell (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) David G. Whitten (Albuquerque, New Mexico);  Kirk S. Schanze (Gainesville, Florida);  Linnea K. Ista (Albuquerque, New Mexico);  Patrick L. Donabedian (Gainesville, Florida);  Eva Yung Hua Chi (Albuquerque, New Mexico);  Florencia A. Monge (Albuquerque, New Mexico);  Alison Meredith Kell (Albuquerque, New Mexico)
ABSTRACT A method of inactivating an enveloped ssRNA virus, such as SARS-CoV-2. The method involves contacting the enveloped ssRNA virus with an antiviral polyelectrolyte compound and/or a conjugated aromatic compound effective to inactivate the virus. The disclosure also provides a method of reducing the period of viability of enveloped ssRNA virus, such as SARS-CoV-2, on personal protective equipment, in filtered air, and on surfaces that have come into contact with the virus.
FILED Wednesday, July 28, 2021
APPL NO 18/017813
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/10 (20130101)
A61L 2/18 (20130101)
A61L 2/084 (20130101)
A61L 2/088 (20130101) Original (OR) Class
A61L 2101/38 (20200801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264114 Zheng et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Northeastern University (Boston, Massachusetts);  Soleeva Energy, Inc. (San Jose, California)
ASSIGNEE(S)
INVENTOR(S) Yi Zheng (Canton, Massachusetts);  Ralph Ahlgren (San Jose, California);  Xiaojie Liu (Boston, Massachusetts);  Yanpei Tian (Boston, Massachusetts);  Mohamed Sonbaty (San Jose, California);  Khushnood Ahmad Qazi (Los Altos, California)
ABSTRACT A floatable interfacial solar-driven evaporation structure includes a water impervious thermal insulation layer adapted to float on a body of water, a porous absorber layer on the water impervious thermal insulation layer, and an interlocked non-woven cotton fiber layer having a portion thereof between the water impervious insulation layer and the porous absorber layer and one or more additional portions configured to extend to the body of water to act as a capillary-driven pump to transport water from the body of water to the porous absorber layer. An ultra-black photothermal paint covers the exposed upper surface of the porous absorber layer to convert solar radiation impinging on the ultra-black photothermal paint into heat for use in generating water vapor from water in the porous absorber layer.
FILED Monday, August 09, 2021
APPL NO 18/041130
CURRENT CPC
Separation
B01D 1/22 (20130101)
B01D 1/0035 (20130101) Original (OR) Class
B01D 5/0066 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/08 (20130101)
C02F 1/14 (20130101)
C02F 2103/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264970 KUNO et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Notre Dame du Lac (South Bend, Indiana);  Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S)
INVENTOR(S) Masaru KUNO (South Bend, Indiana);  Michael BRENNAN (South Bend, Indiana);  Anthony RUTH (South Bend, Indiana);  Ilia PAVLOVETC (South Bend, Indiana);  Jeffrey A. CHRISTIANS (Golden, Colorado);  Taylor Hennessey MOOT (Golden, Colorado);  Joseph Matthew LUTHER (Golden, Colorado)
ABSTRACT Compositions comprise a perovskite and a non-perovskite. Perovskites comprise AxA′yA″(1−x−y)BX3, and non-perovskites may comprise A″, B and X, where A is a first cation, A′ is a second cation, A″ is a third cation, B is a fourth cation, X is an anion. In some instances, A, A′, and A″ are each independently (NH2)2CH+, CH3NH3+, Cs+, Rb+, or (NH2)2(C═NH2)+, with the proviso that A, A′, and A″ are each different. The perovskite may have a first crystal structure in which the anion is corner-sharing, the non-perovskite may have a second crystal structure comprising at least one of an orthorhombic structure, a hexagonal structure, or a perovskite-like structure, and 1−x−y may be greater than about 0.15.
FILED Friday, July 02, 2021
APPL NO 18/003776
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/005 (20130101)
B05D 3/007 (20130101)
B05D 2601/28 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 21/16 (20130101) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/34 (20130101)

Organic electric solid-state devices
H10K 30/10 (20230201)
H10K 30/50 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264983 Meegoda et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) New Jersey Institute of Technology (Newark, New Jersey)
ASSIGNEE(S) New Jersey Institute of Technology (Newark, New Jersey)
INVENTOR(S) Jay Meegoda (Orange, New Jersey);  Jitendra Kewalramani (Iselin, New Jersey)
ABSTRACT A treatment method and system using high-frequency ultrasound for treating a waste stream containing per- and polyfluoroalkyl substance (PFAS) is disclosed. The system has one or more reactors including one or more transducers configured to operating at one or more frequencies to destroy or mineralize the per- and polyfluoroalkyl substances (PFAS) in the waste stream using sonolysis.
FILED Friday, September 03, 2021
APPL NO 18/024423
CURRENT CPC
Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/0607 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/36 (20130101) Original (OR) Class
C02F 1/68 (20130101)
C02F 2101/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265377 Sniadecki et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Nathan J. Sniadecki (Seattle, Washington);  Ty Higashi (Seattle, Washington);  Daniel Moskowitz (Seattle, Washington);  Jevne Micheau-Cunningham (Seattle, Washington);  Robert Bruce Darling (Seattle, Washington)
ABSTRACT Devices and methods configured to determine characteristics of tissue specimens are provided. Representative tissue analysis devices include a sensing module and a reference module. The sensing module includes a first post and a second post configured to have the tissue specimen affixed thereto, and a displacement sensor configured to output a displacement signal corresponding to a displacement of the first post. The reference module includes a reference sensor configured to output a reference signal corresponding to a reference input such as an ambient magnetic field. The devices further include instructions that determine: a displacement value based upon the displacement signal; a reference value based upon the reference signal; a reference-canceled displacement value based upon the displacement value and the reference value; and a characteristic of the tissue specimen based upon the reference-canceled displacement value.
FILED Wednesday, October 07, 2020
APPL NO 17/766876
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101)
C12M 23/12 (20130101)
C12M 35/04 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/4833 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265447 Voytas et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S)
INVENTOR(S) Daniel F. Voytas (Falcon Heights, Minnesota);  Ryan A. Nasti (Berkeley, California);  Michael F. Maher (St. Paul, Minnesota)
ABSTRACT Materials and methods for inducing genetic alterations in meristematic plant tissue are provided herein.
FILED Friday, March 03, 2023
APPL NO 18/178290
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 4/008 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8213 (20130101)
C12N 15/8229 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6895 (20130101)
C12Q 2600/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265477 Martin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) University Of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Craig Martin (Amherst, Massachusetts);  Elvan Cavac (Northampton, Massachusetts);  Kithmie Harshana Malagodapathiranage (Amherst, Massachusetts);  Shuo Sui (Sunderland, Massachusetts);  Sarah L. Perry (Belchertown, Massachusetts);  Yasaman Gholamalipour (Worcester, Massachusetts)
ABSTRACT Described herein are synthetic methods for producing sequence-specific RNA oligonucleotides that eliminate impurities produced in prior art methods. In one aspect, an end-protected capture DNA complementary to a portion of the product RNA is employed. In another aspect, the template DNA is covalently or noncovalently linked to the RNA polymerase, either directly or through the use of a nontemplate DNA. In a third aspect, a flow chamber is employed. All of the methods can be used in combination.
FILED Tuesday, January 10, 2023
APPL NO 18/152367
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1247 (20130101)
C12N 15/10 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6865 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265487 Seelig et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Georg Seelig (Seattle, Washington);  Richard Muscat (Seattle, Washington);  Alexander B. Rosenberg (Seattle, Washington)
ABSTRACT Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
FILED Thursday, March 23, 2023
APPL NO 18/188504
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101) Original (OR) Class
C12Q 1/6855 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265571 Hugar et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Ecolectro, Inc (lthaca, New York)
ASSIGNEE(S)
INVENTOR(S) Kristina Hugar (Ithaca, New York);  Gabriel Rodriguez-Calero (Willseyville, New York);  Sarah Nathan (Wilmington, Delaware);  Sarah Louise Poole (Syracuse, New York)
ABSTRACT The present disclosure relates to composite materials comprising a reinforcement material and a cationic polyelectrolyte, such as a porous reinforcement material impregnated with the cationic poly electrolyte. The present disclosure further relates to membrane electrode assemblies comprising the composites of the disclosure, and electrochemical devices comprising the disclosed membrane electrode assemblies.
FILED Tuesday, August 10, 2021
APPL NO 18/020473
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 9/23 (20210101)
C25B 13/07 (20210101)
C25B 13/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265572 Kuhl et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Twelve Benefit Corporation (Berkeley, California)
ASSIGNEE(S)
INVENTOR(S) Kendra Kuhl (Oakland, California);  Etosha Cave (Berkeley, California);  Nicholas Flanders (San Francisco, California);  Sichao Ma (Dublin, California);  Qun Zeng (Oakland, California);  George Leonard (Oakland, California)
ABSTRACT A system preferably including a carbon dioxide reactor. A method for carbon dioxide reactor control, preferably including selecting carbon dioxide reactor aspects based on a desired output composition, running a carbon dioxide reactor under controlled process conditions to produce a desired output composition, and/or altering the process conditions to alter the output composition.
FILED Wednesday, November 02, 2022
APPL NO 18/051944
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/02 (20130101)
C25B 9/23 (20210101)
C25B 9/70 (20210101)
C25B 11/031 (20210101)
C25B 15/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266943 Seok et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S)
INVENTOR(S) Mingoo Seok (Tenafly, New Jersey);  Dewei Wang (New York, New York);  Chuan-Tung Lin (New York, New York)
ABSTRACT Various embodiments described herein provide for a digital In-Memory Computing (IMC) macro circuit that utilizes approximate arithmetic hardware to reduce the number of transistors and devices in the circuit relative to a convention digital IMC, thereby improving the area-efficiency of the digital IMC, but while retaining the benefits of reduced variability relative to an analog-mixed-signal (AMS) circuit. The proposed digital IMC macro circuit also includes custom full adder (FA) circuits with pass gate logic in a ripple carry adder (RCA) tree. The disclosed digital IMC macro circuit can also perform a vector-matrix dot product in one cycle while achieving high energy and area efficiency.
FILED Wednesday, February 15, 2023
APPL NO 18/110152
CURRENT CPC
Electric Digital Data Processing
G06F 7/501 (20130101)
G06F 7/5312 (20130101)
G06F 7/5443 (20130101) Original (OR) Class

Pulse Technique
H03K 19/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266972 Rogers et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Timothy Glenn Rogers (West Lafayette, Indiana);  Mahmoud Khairy (West Lafayette, Indiana)
ABSTRACT A system may include a central processing unit (CPU) having a Simultaneous Multi-Threading (SMT) thread/execution model. The system may further include a request processing unit (RPU) having an Out-of-Order Single Instruction Multiple Thread (SIMT) execution model. The CPU may receive a plurality of requests. The CPU may group a portion of the requests in a batch. The CPU may cause the RPU to execute instructions corresponding to each request in the batch. The RPU may execute, with a plurality of threads, the instructions corresponding to the batch of requests in lockstep.
FILED Wednesday, November 30, 2022
APPL NO 18/072492
CURRENT CPC
Electric Digital Data Processing
G06F 9/3842 (20130101)
G06F 9/3851 (20130101) Original (OR) Class
G06F 9/4881 (20130101)
G06F 9/30087 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267284 Garg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Divyansh Garg (Stanford, California);  Skanda Vaidyanath (Stanford, California)
ABSTRACT Systems and methods for automated response to natural language instructions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for training an agent, the method including sampling an instruction and observation pair from a dataset, predicting a skill code, using a skill predictor, based on the instruction and observation pair, predicting, for each of a plurality of timesteps, a set of one or more actions based on the predicted skill code and a state history using a policy, and updating the skill predictor and the policy based on a comparison of the predicted set of actions and the observation. In many embodiments, the trained agent can then be used to carry out natural language instructions.
FILED Wednesday, February 22, 2023
APPL NO 18/172969
CURRENT CPC
Electric Digital Data Processing
G06F 40/44 (20200101)
G06F 40/55 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267324 Seif Tabrizi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
Directorate for Mathematical and Physical Sciences (MPS)
Office of Multidisciplinary Activities (OMA)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Seyed Alireza Seif Tabrizi (Adelphi, Maryland);  Changhun Oh (Chicago, Illinois);  Tao Hong (San Jose, California);  Liang Jiang (Chicago, Illinois)
ABSTRACT A machine learning method for model-free inference of target physical parameters from a metrology dataset is generally disclosed. The disclosed method is particularly applied to atomic interferometry for sensing/measuring physical quantities such as acceleration and rotations from measured atomic interference patterns. The method operates without a need for an exact measurement-dependent mathematical/analytical model and without a need for explicit knowledge of instrumental error processes that affect the measurement. The disclosed method is based on neural networks that are trained or calibrated to learn to simultaneously estimate the target physical quantities of interest and their measurement uncertainties. It extends the applicability of a metrology when instrumental precision is limited, and noise and imperfections are present.
FILED Friday, December 23, 2022
APPL NO 18/088252
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267361 Clerk et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Aashish Clerk (Chicago, Illinois);  Andrew Lingenfelter (Chicago, Illinois)
ABSTRACT A method and system that harnesses extremely weak Kerr-type nonlinearities in a single driven cavity to deterministically generate single photon Fock states, and more general photon-blockaded states are disclosed. The disclosed scheme is effective even for nonlinearities that are much smaller than photonic loss in the cavity. The disclosed scheme generates photon-blockade states that are non-Gaussian, exhibit a sharp cut-off in their photon number distribution, and can be arbitrarily close to, for example, a single-photon Fock state. This scheme relies only standard linear and parametric drives, and are hence compatible with a variety of different photonic platforms.
FILED Monday, January 30, 2023
APPL NO 18/161569
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/40 (20220101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267369 KALIVAS et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) IDAHO STATE UNIVERSITY (Pocatello, Idaho)
ASSIGNEE(S)
INVENTOR(S) JOHN KALIVAS (POCATELLO, Idaho);  ROBERT SPIERS (BOISE, Idaho)
ABSTRACT Methodologies and corresponding systems for a Local adaptive fusion regression (LAFR) process are able to search a large library of spectral measurement for a linear calibration (training) set, which is spectrally matrix matched to a target sample spectrum, and also tightly bracketed about an “unknown” prediction property (analyte) for the target sample. Using a matched calibration set, the likelihood of an accurate prediction by the selected calibration set is greatly enhanced. The LAFR process integrates multiple spectral similarity information with contextual considerations between source analyte contents, model, and analyte predictions. LAFR facilitates onsite chemical analysis such as with a handheld spectrometer, dedicated in-line process analyzers and benchtop instruments. LAFR is based on a Beer’s law like linear relationship where a calibration model (mathematical relationship) is made that linearly relates the analyte amount, e.g., concentration, to the measured spectral responses. The calibration model is then used to predict (quantitate) the analyte amounts present in new samples.
FILED Wednesday, November 30, 2022
APPL NO 18/072090
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101) Original (OR) Class

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 40/20 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267720 MARVASTI et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S)
INVENTOR(S) Ehsan Emad MARVASTI (Orlando, Florida);  Arash RAFTARI (Orlando, Florida);  Yaser Pourmohammadi FALLAH (Oviedo, Florida)
ABSTRACT Situational awareness as a necessity in connected and autonomous vehicles domain is a subject of significant research in recent years. The driver’s safety is directly dependent on robustness, reliability and scalability of such systems. Cooperative mechanisms have provided a solution to improve situational awareness by utilizing communication networks. These mechanisms mitigate problems such as occlusion and sensor range limitation. However, the network capacity is a factor determining the maximum amount of information being shared among cooperative entities. A focus of this work is to reduce the network capacity requirements while maintaining the desirable object detection performance by utilizing and modifying the concept of feature sharing. Described here is a mechanism to further improve object detection performance by utilizing novel decentralized parallel frameworks and anew shared data alignment method to allow parallel and cooperative processing of sensed data in multiple locations yielding significant improvements in object detection.
FILED Friday, June 11, 2021
APPL NO 17/928473
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 17/89 (20130101)

Image Data Processing or Generation, in General
G06T 7/73 (20170101)
G06T 2207/10028 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30252 (20130101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101) Original (OR) Class
G06V 20/56 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268170 LI et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) West Virginia University (Morgantown, West Virginia)
ASSIGNEE(S)
INVENTOR(S) Peng LI (Morgantown, West Virginia);  Xiaojun LI (Morgantown, West Virginia);  Stephen J. VALENTINE (Morgantown, West Virginia);  Lisa HOLLAND (Morgantown, West Virginia)
ABSTRACT In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to a vibrating sharp edge spray ionization (VSSI) method suitable for coupling with a mass spectrometer, a VSSI method modified with a capillary suitable for use with continuous-flow separation methods such as liquid chromatography, and a VSSI method suitable for coupling with a capillary electrophoresis (CE) device in order to introduce the CE sample flow into a mass spectrometer. Also disclosed herein are devices for carrying out these methods and methods of making the same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
FILED Wednesday, February 22, 2023
APPL NO 18/172780
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/16 (20130101) Original (OR) Class
H01J 49/0031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268483 Ellison et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota);  Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S)
INVENTOR(S) Christopher John Ellison (Eden Prairie, Minnesota);  Charles Buddie Mullins (West Lake Hills, Texas);  Samantha Nicole Lauro (Austin, Texas);  Joshua Paul Pender (Glendale, Wisconsin);  Han Xiao (Minneapolis, Minnesota);  Jason Alexander Weeks, JR. (Austin, Texas);  James Norman Burrow, JR. (Austin, Texas)
ABSTRACT A method of making a porous film includes disposing a slurry on a substrate, solidifying the slurry to yield a film on the substrate, and subliming the organic sublimable material to yield the porous film on the substrate. The slurry includes an electrochemically active material, an electrically conductive material, and a binder dispersed in an organic sublimable material. The electrochemically active material and the electrically conductive material are different. A slurry includes a solid component including an electrochemically active material, an electrically conductive material, and a binder; and a liquid component including an organic sublimable material, wherein the electrochemically active material and the electrically conductive material are different, and the solid component is dispersed in the liquid component.
FILED Tuesday, February 21, 2023
APPL NO 18/112130
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/18 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/366 (20130101)
H01M 4/0404 (20130101)
H01M 4/0433 (20130101)
H01M 4/0485 (20130101)
H01M 4/485 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/622 (20130101)
H01M 4/623 (20130101)
H01M 4/1391 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268721 Yang et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
National Science Foundation (NSF)
APPLICANT(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma);  Sandia National Laboratories (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Rui Q. Yang (Norman, Oklahoma);  John F. Klem (Albuquerque, New Mexico)
ABSTRACT An ICL comprises: a plurality of IC stages, wherein each of the IC stages comprises: a hole injector; an electron injector; an active region coupled to the hole injector and the electron injector and comprising a first layer, wherein the first layer comprises a first material, and wherein the first material comprises InAsP or AlInAsP; a conduction band running through the hole injector, the electron injector, and the active region; and a valence band running through the hole injector, the electron injector, and the active region.
FILED Monday, February 13, 2023
APPL NO 18/168337
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/3402 (20130101) Original (OR) Class
H01S 5/3422 (20130101)
H01S 5/34306 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268945 Peroulis et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S)
INVENTOR(S) Dimitrios Peroulis (West Lafayette, Indiana);  Mohammad Abu Khater (West Lafayette, Indiana)
ABSTRACT Systems and methods for wideband RF interference detection and suppression include an open-circuit stub, a first voltage peak detector, a second voltage peak detector, an analog-to-digital converter (ADC), and a controller. The open-circuit stub is configured to receive an input signal. The first voltage peak detector is coupled at the open end of the open-circuit stub and configured to output a first voltage signal based on a portion of the input signal. The second voltage peak detector is coupled a distance away from the open end of the open-circuit stub and configured to output a second voltage signal based on the portion of the input signal. The controller is configured to generate an output control signal operable to adjust a signal filter based on the first digital voltage signal and the second digital voltage signal to suppress the portion of the input signal.
FILED Wednesday, February 22, 2023
APPL NO 18/112604
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 19/04 (20130101)

Transmission
H04B 1/1027 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230269202 Xu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)
INVENTOR(S) Jun Xu (Atlanta, Georgia);  Long Gong (Atlanta, Georgia);  Jingfan Meng (Atlanta, Georgia)
ABSTRACT An exemplary sliding window scheduling method and system are disclosed. The exemplary sliding window scheduling method and system can schedule multiple packets in a given scheduling frame with a sliding window scheduling frame. The scheduling operation can be performed using bitmap operators and can achieve a lowest time complexity of O(1) per matching computation and per port using distributed parallelization hardware. The exemplary sliding window scheduling method and system can be performed in the context of a queue-proportional scheduler (QPS) as well as iSLIP. In alternative embodiments, the SW-QPS operation can be performed in a batching window rather than in a sliding window.
FILED Wednesday, August 11, 2021
APPL NO 18/020822
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 47/28 (20130101)
H04L 47/225 (20130101)
H04L 49/3027 (20130101)
H04L 49/3045 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230269377 Kodukula et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Venkatesh Kodukula (Tempe, Arizona);  Alexander Shearer (Tempe, Arizona);  Van Nguyen (Madison, Wisconsin);  Srinivas Lingutla (Chicago, Illinois);  Robert LiKamWa (Tempe, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona)
INVENTOR(S) Venkatesh Kodukula (Tempe, Arizona);  Alexander Shearer (Tempe, Arizona);  Van Nguyen (Madison, Wisconsin);  Srinivas Lingutla (Chicago, Illinois);  Robert LiKamWa (Tempe, Arizona)
ABSTRACT A system defining a visual sensing pipeline architecture flexibly allows application developers to dynamically adapt the spatial resolution and update rate of different “rhythmic pixel encoding regions” in a scene. The system ingests pixel streams with raster-scan pixel read-out patterns, but only encodes relevant pixels prior to storing them in memory. The system includes streaming hardware to decode the stored rhythmic pixel encoding region stream into traditional frame-based representations to feed into standard computer vision algorithms.
FILED Friday, February 24, 2023
APPL NO 18/174259
CURRENT CPC
Pictorial Communication, e.g Television
H04N 19/33 (20141101)
H04N 19/132 (20141101) Original (OR) Class
H04N 19/167 (20141101)
H04N 19/172 (20141101)
H04N 19/182 (20141101)
H04N 19/423 (20141101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 20230263392 Cascales Sandoval et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Juan Pedro Cascales Sandoval (Somerville, Massachusetts);  Conor L. Evans (Charlestown, Massachusetts)
ABSTRACT A sensor system includes a probe, and a photon source configured to direct photons at the probe. The probe can emit light in response to receiving photons. The sensor system can include a photodetector configured to detect the light emitted from the probe, and a configured to cause the photon source to emit photons according to a first time-varying intensity profile having a first frequency. The controller can be configured to receive optical data from the photodetector based on the interaction between the light emitted from the probe and the photodetector. The optical data can include a second time-varying intensity profile having a second frequency. The second frequency can be substantially the same as the first frequency. The controller can be configured to determine a difference in phase between the first time-varying intensity profile and the second time-varying intensity profile, and generate a report based on the difference in phase.
FILED Wednesday, September 01, 2021
APPL NO 18/043659
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0008 (20130101) Original (OR) Class
A61B 2562/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263932 Brown et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Embody, Inc. (Norfolk, Virginia)
ASSIGNEE(S)
INVENTOR(S) Robert S. Brown (Norfolk, Virginia);  Caitlin Harclerode (Norfolk, Virginia);  Nardos Sori (Norfolk, Virginia);  Michael P. Francis (Norfolk, Virginia);  Nicholas Thayer (Morrisville, North Carolina)
ABSTRACT An implantable biopolymer scaffold includes at least one braided strand comprising high strength collagen fibers and synthetic fibers, wherein the collagen fibers have a greater cross-sectional deform ability than the synthetic fibers.
FILED Thursday, February 09, 2023
APPL NO 18/167051
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 17/08 (20130101)
A61L 17/14 (20130101) Original (OR) Class
A61L 17/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264006 Kamen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) DEKA Products Limited Partnership (Manchester, New Hampshire)
ASSIGNEE(S)
INVENTOR(S) Dean Kamen (Bedford, New Hampshire);  Lee A. Batchelder (Auburn, New Hampshire);  Eitan C. Zeira (Hollis, New Hampshire);  Linda R. Rios Guevara (Manchester, New Hampshire);  Joshua A. Frye (Manchester, New Hampshire);  Hans E. Johnson (Salem, New Hampshire)
ABSTRACT A delivery device for delivery of medical agent to a barrier may comprise a main body including a central region defining a receptacle, a peripheral region defined by a number of petal members, and a set of retention tabs extending into the receptacle. The delivery device may further comprise a reservoir including at least one delivery sharp, a main interior volume, and at least one septum in fluid communication with the main interior volume. The reservoir may be coupled to the main body via the retention tabs. The delivery device may further comprise an adhesive coupled to the main body. The delivery device may further comprise at least one bias member positioned within the receptacle between the reservoir and a wall of the receptacle.
FILED Thursday, December 22, 2022
APPL NO 18/087058
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0015 (20130101) Original (OR) Class
A61M 2037/0023 (20130101)
A61M 2037/0061 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264148 Boettcher et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) University of Oregon (Eugene, Oregon)
ASSIGNEE(S) University of Oregon (Eugene, Oregon)
INVENTOR(S) Shannon Boettcher (Eugene, Oregon);  Lihaokun Chen (Eugene, Oregon);  James Mitchell (Eugene, Oregon);  Sayantan Sasmal (Eugene, Oregon);  Nicole Sagui (Eugene, Oregon);  Prasad Sarma (Eugene, Oregon)
ABSTRACT A bipolar membrane comprising a first member comprising at least one anion exchange material; a second member comprising at least one cation exchange material, wherein the first member and the second member together form an interface junction; and disposed within the interface junction a solitary layer comprising a composite water dissociation catalyst or a composite water recombination catalyst.
FILED Wednesday, February 22, 2023
APPL NO 18/112868
CURRENT CPC
Separation
B01D 61/445 (20130101) Original (OR) Class
B01D 69/02 (20130101)
B01D 2325/10 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/04 (20130101)
C25B 11/052 (20210101)
C25B 11/077 (20210101)
C25B 11/091 (20210101)
C25B 13/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264358 Blankespoor et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) BOSTON DYNAMICS, INC. (Waltham, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Kevin Blankespoor (Arlington, Massachusetts);  Benjamin Stephens (Somerville, Massachusetts);  Marco da Silva (Arlington, Massachusetts)
ABSTRACT An example method may include i) detecting a disturbance to a gait of a robot, where the gait includes a swing state and a step down state, the swing state including a target swing trajectory for a foot of the robot, and where the target swing trajectory includes a beginning and an end; and ii) based on the detected disturbance, causing the foot of the robot to enter the step down state before the foot reaches the end of the target swing trajectory.
FILED Wednesday, April 12, 2023
APPL NO 18/299645
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/16 (20130101)
B25J 9/1628 (20130101)
B25J 9/1679 (20130101)
B25J 9/1692 (20130101) Original (OR) Class

Motor Vehicles; Trailers
B62D 57/032 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
Y10S 901/46 (20130101)
Y10S 901/49 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264972 Hennighausen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Zachariah B. Hennighausen (Newton, Massachusetts);  Bethany Hudak (Accokeek, Maryland);  Olaf M.J. van 't Erve (Falls Church, Virginia);  Madeleine Phillips (Alexandria, Virginia)
ABSTRACT A nano-thin BixOySez low-temperature oxygen transporter membrane for oxygen transport, separation, and two-dimensional (2D) material manipulation comprising a material comprising a compound of BixOySez and R3m bismuth oxide (Bi2O3). A method of making a nano-thin BixOySez low-temperature oxygen transporter membrane for oxygen transport, separation, and two-dimensional (2D) material manipulation comprising providing an oxygen environment, providing Bi2Se3, processing the Bi2Se3 in the oxygen environment, incorporating oxygen, removing selenium, creating a structural change, and creating a compound of BixOySez and R3m bismuth oxide (Bi2O3), wherein the material transports oxygen at room temperature.
FILED Thursday, February 23, 2023
APPL NO 18/113285
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 29/00 (20130101) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/01 (20130101)
C01P 2002/20 (20130101)
C01P 2002/82 (20130101)
C01P 2004/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265311 Pojman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) John Anthony Pojman (Baton Rouge, Louisiana);  Daniel Paul Gary (Sulphur, Louisiana)
ASSIGNEE(S) Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S) John Anthony Pojman (Baton Rouge, Louisiana);  Daniel Paul Gary (Sulphur, Louisiana)
ABSTRACT The present invention relates to a resin composition comprising 20-70 wt % of an aromatic di(meth)acrylate component; 5-25 wt % of a flexible di(meth)acrylate component; and 10-70 wt % of a crosslinker component; wherein the resin composition further comprises: 0.1-10 phr initiator; 0-10 phr silica; and 5-50 phr milled carbon fiber. The invention also relates to a polymerized coating disposed over a substrate, the coating comprising 20-70 wt % aromatic di(meth)acrylate subunits; 5-25 wt % flexible di(meth)acrylate subunits; and 10-70 wt % crosslinker subunits; wherein the coating further comprises: 0.1-10 phr silica; and 5-50 phr milled carbon fiber. The invention also relates to a method of depositing a coating over a substrate, the method comprising the steps of: providing a resin composition; applying the resin composition over a substrate; and polymerizing the resin composition to form a solid coating.
FILED Wednesday, November 23, 2022
APPL NO 18/058352
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 3/108 (20130101)
B05D 3/0254 (20130101)
B05D 7/14 (20130101)
B05D 2202/15 (20130101)
B05D 2502/00 (20130101)
B05D 2601/22 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/04 (20130101)
C08K 3/36 (20130101)
C08K 5/14 (20130101)

Compositions of Macromolecular Compounds
C08L 33/10 (20130101)
C08L 2312/00 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 7/61 (20180101)
C09D 7/63 (20180101)
C09D 133/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265387 Gros et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Alena Gros (Barcelona, Spain);  Steven A. Rosenberg (Potomac, Maryland)
ABSTRACT Methods of obtaining a cell population enriched for tumor-reactive T cells, the method comprising: (a) obtaining a bulk population of T cells from a tumor sample; (b) specifically selecting CD8+ T cells that express any one or more of TIM-3, LAG-3, 4-1BB, and PD-1 from the bulk population; and (c) separating the cells selected in (b) from unselected cells to obtain a cell population enriched for tumor-reactive T cells are disclosed. Related methods of administering a cell population enriched for tumor-reactive T cells to a mammal, methods of obtaining a pharmaceutical composition comprising a cell population enriched for tumor-reactive T cells, and isolated or purified cell populations are also disclosed.
FILED Friday, January 06, 2023
APPL NO 18/093902
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 39/0011 (20130101)
A61K 2039/5158 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101) Original (OR) Class
C12N 5/0638 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266197 Posada
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S)
INVENTOR(S) Natalia Posada (Dayton, Ohio)
ABSTRACT A portable tracer fluid injection system. The system has a vapor cloud generator which vaporizes a vapor cloud generating liquid. The vapor cloud generator is uses a sub-ohm resistive heater to vaporize small volumes of the vapor cloud generating liquid, allowing for a relatively small tracer fluid injection system. This system has the benefit of being able to target specific regions of a test object within a wind tunnel and being usable for different positions within the test section of a wind tunnel.
FILED Monday, April 10, 2023
APPL NO 18/297674
CURRENT CPC
Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 9/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266274 Giurgiutiu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) University of South Carolina (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Victor Giurgiutiu (Columbia, South Carolina);  Jingjing Bao (West Columbia, South Carolina);  Banibrata Poddar (Germantown, Maryland);  Md Yeasin Bhuiyan (West Columbia, South Carolina)
ABSTRACT The current disclosure determines if structural faults exist and extracts geometric features of the structural faults from acoustic emission waveforms, such as crack length and orientation, and can evaluate the structural faults online, during normal operation conditions.
FILED Tuesday, April 11, 2023
APPL NO 18/298508
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/14 (20130101) Original (OR) Class
G01N 29/46 (20130101)
G01N 29/2437 (20130101)
G01N 29/4454 (20130101)
G01N 2291/0231 (20130101)
G01N 2291/0232 (20130101)
G01N 2291/0258 (20130101)
G01N 2291/0289 (20130101)
G01N 2291/2634 (20130101)
G01N 2291/2693 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266329 LYDEN et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S)
INVENTOR(S) David C. LYDEN (Old Chatham, New York);  Haiying ZHANG (New York, New York)
ABSTRACT The present invention is directed to methods of diagnosing, prognosing, and managing treatment of cancer in a subject. These methods involve selecting a subject having cancer and obtaining, from the selected subject, a population of either exomeres having a diameter less than 50 nm, small exosomes having a diameter of 60-80 nm, or large exosomes having a diameter of 90-120 nm. The exomeres, small exosomes, or large exosomes are recovered from the sample, and the exomeres, small exosomes, or large exosomes or portions thereof are contacted with one or more reagents suitable to detect: (1) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more proteins contained in said exomeres, small exosomes, or large exosomes, (2) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more N-glycans contained in said exomeres, small exosomes, or large exosomes, (3) higher or lower levels, relative to a standard for subjects not having cancer, or the presence or absence, of one or more lipids contained in said exomeres, small exosomes, or large exosomes, (4) the presence or absence of one or more genetic mutations in nucleic acid molecules associated with cancer and contained in said exomeres, small exosomes, or large exosomes, or (5) combinations thereof. Cancer is then diagnosed, prognosed, or treatment is modified based on this information.
FILED Thursday, December 15, 2022
APPL NO 18/082368
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/118 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/68 (20130101)
G01N 33/6893 (20130101)
G01N 33/57484 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266418 Kulam Najmudeen et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland);  The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
ASSIGNEE(S) The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland);  The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
INVENTOR(S) Magdoom Mohamed Kulam Najmudeen (Bethesda, Maryland);  Peter J. Basser (Bethesda, Maryland);  Michal E. Komlosh (Bethesda, Maryland)
ABSTRACT Diffusion sensitizing gradient pulse pairs are prescribed in a manner to mitigate effects of concomitant gradient artifacts. Measured MR signals generated by applying a plurality of diffusion sensitizing gradient matrices are obtained and processed to determine a second order mean diffusion tensor and a fourth order covariance tensor. Quantities derived from these tensors are measured and mapped within an imaging volume which describe features of diffusion anisotropy and heterogeneity within each imaging voxel.
FILED Thursday, July 08, 2021
APPL NO 18/017150
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/022 (20130101)
G01R 33/246 (20130101)
G01R 33/56341 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266715 Robinson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Jeremy T. Robinson (Washington, District of Columbia);  Woodruff T. Sullivan (Seattle, Washington)
ABSTRACT A miniaturized apparatus for tracking the apparent motion of the sun comprising a light mask, a pixilated image sensor, and an image processing unit, wherein sunlight transmitted through the light mask allows the miniaturized apparatus to make time, latitude, direction, and date measurements. A method of making a miniaturized apparatus for tracking the apparent motion of the sun comprising the steps of providing a light mask, providing a pixilated image sensor, providing an image processing unit, and resulting in a miniaturized apparatus for tracking the apparent motion of the sun.
FILED Wednesday, February 22, 2023
APPL NO 18/113044
CURRENT CPC
Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0005 (20130101)

Mechanically-driven Clocks or Watches; Mechanical Parts of Clocks or Watches in General; Time Pieces Using the Position of the Sun, Moon or Stars
G04B 49/02 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/246 (20170101)

Pictorial Communication, e.g Television
H04N 25/76 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266753 Landry et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Blake J. Landry (Saint Martinville, Louisiana);  William David Null (Urbana, Illinois)
ABSTRACT A system having a networking device, a plurality of processing devices, and one or more unmanned devices, wherein each unmanned device couples to a corresponding one of the processing devices, wherein each unmanned device comprises one or more operational components. The system having a controller device configured to control at least one of the one or more unmanned devices via the networking device and the corresponding one of the processing devices, the controller device comprising one of the processing devices, wherein the controlled at least one unmanned device is configurable via the corresponding processing device in a control operating mode or in a robot operating mode, the control operating mode enabling the associated unmanned device to perform commands received from the controller device via the corresponding processing device, and the robot operating mode enabling the unmanned device to receive programmable instructions from the controller device via the corresponding processing device.
FILED Thursday, October 06, 2022
APPL NO 17/961382
CURRENT CPC
Systems for Controlling or Regulating Non-electric Variables
G05D 1/0016 (20130101) Original (OR) Class
G05D 1/0022 (20130101)
G05D 1/0088 (20130101)
G05D 2201/0207 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267284 Garg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Divyansh Garg (Stanford, California);  Skanda Vaidyanath (Stanford, California)
ABSTRACT Systems and methods for automated response to natural language instructions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for training an agent, the method including sampling an instruction and observation pair from a dataset, predicting a skill code, using a skill predictor, based on the instruction and observation pair, predicting, for each of a plurality of timesteps, a set of one or more actions based on the predicted skill code and a state history using a policy, and updating the skill predictor and the policy based on a comparison of the predicted set of actions and the observation. In many embodiments, the trained agent can then be used to carry out natural language instructions.
FILED Wednesday, February 22, 2023
APPL NO 18/172969
CURRENT CPC
Electric Digital Data Processing
G06F 40/44 (20200101)
G06F 40/55 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267324 Seif Tabrizi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
Office of Emerging Frontiers and Multidisciplinary Activities (EFMA)
Directorate for Mathematical and Physical Sciences (MPS)
Office of Multidisciplinary Activities (OMA)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Seyed Alireza Seif Tabrizi (Adelphi, Maryland);  Changhun Oh (Chicago, Illinois);  Tao Hong (San Jose, California);  Liang Jiang (Chicago, Illinois)
ABSTRACT A machine learning method for model-free inference of target physical parameters from a metrology dataset is generally disclosed. The disclosed method is particularly applied to atomic interferometry for sensing/measuring physical quantities such as acceleration and rotations from measured atomic interference patterns. The method operates without a need for an exact measurement-dependent mathematical/analytical model and without a need for explicit knowledge of instrumental error processes that affect the measurement. The disclosed method is based on neural networks that are trained or calibrated to learn to simultaneously estimate the target physical quantities of interest and their measurement uncertainties. It extends the applicability of a metrology when instrumental precision is limited, and noise and imperfections are present.
FILED Friday, December 23, 2022
APPL NO 18/088252
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267356 MONROE et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S)
INVENTOR(S) Christopher MONROE (Ellicott City, Maryland);  Marko CETINA (College Park, Maryland);  Norbert LINKE (Stevenson, Maryland);  Shantanu DEBNATH (College Park, Maryland)
ABSTRACT The disclosure describes various aspects of optical control of atomic quantum bits (qubits) for phase control operations. More specifically, the disclosure describes methods for coherently controlling quantum phases on atomic qubits mediated by optical control fields, applying to quantum logic gates, and generalized interactions between qubits. Various attributes and settings of optical/qubit interactions (e.g., atomic energy structure, laser beam geometry, polarization, spectrum, phase, background magnetic field) are identified for imprinting and storing phase in qubits. The disclosure further describes how these control attributes are best matched in order to control and stabilize qubit interactions and allow extended phase-stable quantum gate sequences.
FILED Monday, April 24, 2023
APPL NO 18/305954
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Optical Computing Devices;
G06E 1/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267361 Clerk et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Aashish Clerk (Chicago, Illinois);  Andrew Lingenfelter (Chicago, Illinois)
ABSTRACT A method and system that harnesses extremely weak Kerr-type nonlinearities in a single driven cavity to deterministically generate single photon Fock states, and more general photon-blockaded states are disclosed. The disclosed scheme is effective even for nonlinearities that are much smaller than photonic loss in the cavity. The disclosed scheme generates photon-blockade states that are non-Gaussian, exhibit a sharp cut-off in their photon number distribution, and can be arbitrarily close to, for example, a single-photon Fock state. This scheme relies only standard linear and parametric drives, and are hence compatible with a variety of different photonic platforms.
FILED Monday, January 30, 2023
APPL NO 18/161569
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/40 (20220101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267400 Nicotera et al.
FUNDED BY
Department of Defense (DOD)
Defense Logistics Agency (DLA)
APPLICANT(S) Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S)
INVENTOR(S) Paul Nicotera (Ithaca, New York);  Joseph Sirianni (Ithaca, New York);  Ryan Lee Hagelstrom (Chaska, Minnesota);  Robert A. Joyce (Ithaca, New York);  Tyler J. Mitchell (Ithaca, New York);  Kenneth McVearry (Dewitt, New York)
ABSTRACT A warehouse management system may receive a predictive analytics request associated with one or more warehouses and may, in response, input data associated with the one or more warehouses into a warehouse management model to determine one or more predictive analytics associated with the one or more warehouses, where the warehouse management model is trained via machine learning to determine the predictive analytics. The warehouse management system may perform simulations of operations of the one or more warehouses based on the one or more predictive analytics to determine one or more warehouse actions to meet one or more operational requirements. The warehouse management system may communicate the one or more warehouse actions to one or more devices associated with the one or more warehouses to enable the one or more devices to operate according to the one or more warehouse actions to meet the one or more operational requirements.
FILED Thursday, December 15, 2022
APPL NO 18/066782
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/08 (20130101) Original (OR) Class
G06Q 10/06315 (20130101)
G06Q 10/06393 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267607 Sadri et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S)
INVENTOR(S) Amir Reza Sadri (Cleveland Heights, Ohio);  Satish E. Viswanath (Beachwood, Ohio);  Thomas Desilvio (Lyndhurst, Ohio)
ABSTRACT In some embodiments, the present disclosure relates to a non-transitory computer-readable medium storing computer-executable instructions that, when executed, cause a processor to perform operations, including forming an imaging dataset having imaging data corresponding to one or more radiological images of a patient having a bowel disease; operating upon the imaging data with one or more convolutional neural network (CNN) segments configured to generate a plurality of CNN outputs, the one or more CNN segments respectively including a convolution layer configured to perform a convolution on the imaging data; and applying a wavelet network to the plurality of CNN outputs to generate a plurality of convolution wavelet network (CWN) outputs, the wavelet network being configured to decompose the plurality of CNN outputs according to a mother wavelet. A predictive signature associated with disease response or risk is constructed using the plurality of CWN outputs.
FILED Thursday, February 16, 2023
APPL NO 18/169935
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/7275 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/10116 (20130101)
G06T 2207/20064 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/20 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267643 Maryan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Corey Maryan (Bush, Louisiana);  Christopher Michael (Covington, Louisiana);  Steven Dennis (Covington, Louisiana);  Sarah Trimble (New Orleans, Louisiana)
ABSTRACT A method of identifying a rip current that includes receiving an image comprising a body of water, and identifying, in the image an estimated location of a rip current associated with the body of water, wherein the identification comprises a plurality of displayed vertices based on least one of a rip length or a rip width. The method may include digitizing the estimated location of the rip current, the estimated location having highest, lower, and no confidence boundaries. The method may include generating, based on the digitized estimated location, a set of fuzzy-set scheme labels for one or more pixels in the image based on a respective confidence boundary, where the fuzzy-set scheme labels are based on a pixel interpolation associated with the lower confidence boundary, and generating, based on the generated fuzzy-set scheme labels, a refined digitizing of the estimated location of the rip current.
FILED Tuesday, February 21, 2023
APPL NO 18/112472
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 13/006 (20130101)

Image Data Processing or Generation, in General
G06T 7/73 (20170101) Original (OR) Class
G06T 2207/10032 (20130101)
G06T 2207/20061 (20130101)
G06T 2207/20081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268051 Wachs et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Juan Pablo Wachs (West Lafayette, Indiana);  Edgar Javier Rojas-Munoz (West Lafayette, Indiana)
ABSTRACT A system and methods for artificially intelligent medical procedure assessment and intervention are provided. A system may acquire image data from a camera targeting a location where healthcare is administered. The system may receive sensor data from a sensor attached to a care provider during performance of a procedure. The system may generate gesture features based on the sensor data. The system may generate image features based on the image data. The system may determine, based on the image features and a machine learning model, a step identifier for a step in a multi-step surgical procedure. The system may access text descriptive of an instruction to perform the step. The system may display the text on a display accessible to the care provider. The system may determine, based on the gesture information and a second machine learning model, a performance metric that measures performance of the care provider.
FILED Thursday, June 24, 2021
APPL NO 18/012529
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/044 (20230101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101) Original (OR) Class
G16H 30/40 (20180101)
G16H 40/67 (20180101)
G16H 70/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230269502 Black et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Nu-Trek, Inc. (San Diego, California)
ASSIGNEE(S)
INVENTOR(S) Stephen Holden Black (Tennessee Ridge, Tennessee);  Paul Richard Behmen (Chester, California);  Francisco Tejada (Kingsville, Maryland)
ABSTRACT A photodetector interface circuit is described, residing partially or fully within a unit cell per pixel of an FPA. The interface circuit uses an innovative approach to providing pixel level digitization for full frame integration times while maintaining the ability to use integration capacitors of practical sizes. The technique uses successive charge subtraction, removing charge from an integration capacitor successively, triggered by the charge increasing sufficiently to charge the integrator to a reference level, thereby triggering both charge removal and incrementing a count, until all of the current flowing in the photodetector has been accounted for and the count represents the digitization of the photodetector signal. Various options on how to arrange the digitization elements are also disclosed.
FILED Friday, February 17, 2023
APPL NO 18/111257
CURRENT CPC
Pictorial Communication, e.g Television
H04N 25/77 (20230101) Original (OR) Class
H04N 25/78 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230269530 GHAFFARIVARDAVAGH et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Reza GHAFFARIVARDAVAGH (Boston, Massachusetts);  Sayed Saad AFZAL (Cambridge, Massachusetts);  Osvy RODRIGUEZ (Cambridge, Massachusetts);  Fadel ADIB (Cambridge, Massachusetts)
ABSTRACT An ultra-wide bandwidth acoustic transducer may include multiple layers, including an inner piezoelectric layer, a polymer coupling layer and an outer piezoelectric layer. The polymer layer may be located between, and may be bonded to, the inner and outer piezoelectric layers. The transducer may have multiple eigenfrequencies of vibration. These eigenfrequencies may include primary resonant frequencies of the inner and outer piezoelectric layers respectively and may also include resonant frequencies that arise due to coupling between the layers. An acoustic backscatter system may employ such a transducer in backscatter nodes as well as in a transmitter. The multiple eigenfrequencies may enable the system to perform spread-spectrum communication at a high throughput. These multiple eigenfrequencies may also enable each backscatter node to shift frequency of an uplink signal, which in turn may enable the system to mitigate self-interference and to decode concurrent signals from multiple backscatter nodes.
FILED Wednesday, April 26, 2023
APPL NO 18/139563
CURRENT CPC
Transmission
H04B 11/00 (20130101)
H04B 13/02 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 1/44 (20130101) Original (OR) Class
H04R 17/005 (20130101)
H04R 17/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 20230264138 McGrail et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S)
INVENTOR(S) B. Peter McGrail (Pasco, Washington);  Radha K. Motkuri (Richland, Washington)
ABSTRACT An apparatus comprising (A) an atmospheric water extraction unit; and (B) a direct air capture unit positioned downstream of and in communication with the atmospheric water extraction unit, wherein the apparatus is capable of reversibly operating in (i) adsorption mode to adsorb water and CO2 from an incoming air stream and (ii) regeneration mode to release adsorbed water and CO2, wherein the atmospheric water extraction unit comprises a first desiccant bed comprising a sorbent that adsorbs water from an incoming air stream during adsorption mode and releases water during regeneration mode, and wherein the direct air capture unit comprises a first CO2 sorbent bed that adsorbs CO2 from an air stream during adsorption mode and releases CO2 during regeneration.
FILED Tuesday, February 21, 2023
APPL NO 18/112314
CURRENT CPC
Separation
B01D 53/261 (20130101)
B01D 53/0438 (20130101)
B01D 53/0476 (20130101) Original (OR) Class
B01D 2253/204 (20130101)
B01D 2257/80 (20130101)
B01D 2257/504 (20130101)
B01D 2259/404 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264166 BADDOUR et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S)
INVENTOR(S) Frederick G. BADDOUR (Denver, Colorado);  Susan E. HABAS (Boulder, Colorado);  Brittney E. PETEL (Lakewood, Colorado);  Alexander Kenneth YUNG (Fort Collins, Colorado)
ABSTRACT The present disclosure relates to a method of synthesizing metal nanoparticles, where the method includes mixing a metal precursor with a stabilizing ligand in a first zone of a first fluidic device to form a first mixture and mixing the first mixture with a reductant in a second zone of the first fluidic device to form a second mixture, such that the metal nanoparticles form in the second zone.
FILED Thursday, February 23, 2023
APPL NO 18/173317
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0093 (20130101) Original (OR) Class
B01J 2219/0086 (20130101)
B01J 2219/00822 (20130101)
B01J 2219/00824 (20130101)
B01J 2219/00831 (20130101)
B01J 2219/00833 (20130101)
B01J 2219/00889 (20130101)
B01J 2219/00894 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/0547 (20220101)
B22F 9/24 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264420 Marshall et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
APPLICANT(S) UNIVERSITY OF ROCHESTER (Rochester, New York)
ASSIGNEE(S) UNIVERSITY OF ROCHESTER (Rochester, New York)
INVENTOR(S) Kenneth L. Marshall (Rochester, New York);  Stavros G. Demos (Rochester, New York);  Tanya Kosc (Rochester, New York)
ABSTRACT Additive manufacturing systems and methods utilizing an optical light valve configured to spatially modulate the intensity of a laser beam, in conjunction with a writing and erasing sub-system configured to repeatedly write and erase patterns in the optical light valve to repeatedly vary the spatial modulation of the laser beam. In some implementations, the systems and methods may also employ additional laser beams or other energy sources that are not spatially modulated by the optical light valve. In some implementations, the systems and methods may employ additional laser beams or other energy sources configured to reduce surface roughness of the powder or other material being used for additive manufacturing.
FILED Wednesday, July 07, 2021
APPL NO 18/004120
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/00 (20210101)
B22F 10/28 (20210101)
B22F 10/36 (20210101)
B22F 10/38 (20210101)
B22F 10/50 (20210101)
B22F 10/362 (20210101)
B22F 10/364 (20210101)
B22F 12/13 (20210101)
B22F 12/41 (20210101)
B22F 12/43 (20210101)
B22F 12/44 (20210101)
B22F 12/45 (20210101)

Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/064 (20151001)
B23K 26/342 (20151001)
B23K 26/0624 (20151001)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/00 (20170801)
B29C 64/10 (20170801)
B29C 64/20 (20170801)
B29C 64/153 (20170801)
B29C 64/268 (20170801)
B29C 64/282 (20170801) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 30/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230264970 KUNO et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Notre Dame du Lac (South Bend, Indiana);  Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S)
INVENTOR(S) Masaru KUNO (South Bend, Indiana);  Michael BRENNAN (South Bend, Indiana);  Anthony RUTH (South Bend, Indiana);  Ilia PAVLOVETC (South Bend, Indiana);  Jeffrey A. CHRISTIANS (Golden, Colorado);  Taylor Hennessey MOOT (Golden, Colorado);  Joseph Matthew LUTHER (Golden, Colorado)
ABSTRACT Compositions comprise a perovskite and a non-perovskite. Perovskites comprise AxA′yA″(1−x−y)BX3, and non-perovskites may comprise A″, B and X, where A is a first cation, A′ is a second cation, A″ is a third cation, B is a fourth cation, X is an anion. In some instances, A, A′, and A″ are each independently (NH2)2CH+, CH3NH3+, Cs+, Rb+, or (NH2)2(C═NH2)+, with the proviso that A, A′, and A″ are each different. The perovskite may have a first crystal structure in which the anion is corner-sharing, the non-perovskite may have a second crystal structure comprising at least one of an orthorhombic structure, a hexagonal structure, or a perovskite-like structure, and 1−x−y may be greater than about 0.15.
FILED Friday, July 02, 2021
APPL NO 18/003776
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/005 (20130101)
B05D 3/007 (20130101)
B05D 2601/28 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 21/16 (20130101) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/34 (20130101)

Organic electric solid-state devices
H10K 30/10 (20230201)
H10K 30/50 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265349 BUTTS et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) General Electric Technology GmbH (Baden, Switzerland)
ASSIGNEE(S) General Electric Technology GmbH (Baden, Switzerland)
INVENTOR(S) Matthew David BUTTS (Niskayuna, New York);  Weijun YIN (Niskayuna, New York);  Jingjing YANG (Niskayuna, New York);  Jie Jerry LIU (Niskayuna, New York)
ABSTRACT Soluble water scavenger molecules for use with dielectric fluids are disclosed. An example dielectric fluid-based composition for reducing water content in a dielectric fluid may include a water-scavenging agent disposed within a dielectric fluid. The example dielectric fluid-based composition may further include the water-scavenging agent being soluble in the dielectric fluid. The example dielectric fluid-based composition may further include the water-scavenging agent being configured to react with water molecules in the dielectric fluid. The example dielectric fluid-based composition may be disposed in an electrical equipment immersed in oil. The electrical equipment may further include at least one solid insulation in operational contact with the dielectric fluid.
FILED Friday, February 18, 2022
APPL NO 17/676033
CURRENT CPC
Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 33/04 (20130101) Original (OR) Class

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 27/14 (20130101)
H01F 27/32 (20130101)
H01F 27/125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265572 Kuhl et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Twelve Benefit Corporation (Berkeley, California)
ASSIGNEE(S)
INVENTOR(S) Kendra Kuhl (Oakland, California);  Etosha Cave (Berkeley, California);  Nicholas Flanders (San Francisco, California);  Sichao Ma (Dublin, California);  Qun Zeng (Oakland, California);  George Leonard (Oakland, California)
ABSTRACT A system preferably including a carbon dioxide reactor. A method for carbon dioxide reactor control, preferably including selecting carbon dioxide reactor aspects based on a desired output composition, running a carbon dioxide reactor under controlled process conditions to produce a desired output composition, and/or altering the process conditions to alter the output composition.
FILED Wednesday, November 02, 2022
APPL NO 18/051944
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/02 (20130101)
C25B 9/23 (20210101)
C25B 9/70 (20210101)
C25B 11/031 (20210101)
C25B 15/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265822 Wilson et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  Michigan Technological University (Houghton, Michigan)
ASSIGNEE(S)
INVENTOR(S) David G. Wilson (Tijeras, New Mexico);  Raymond H. Byrne (Albuquerque, New Mexico);  Steven F. Glover (Albuquerque, New Mexico);  Tu Anh Nguyen (Albuquerque, New Mexico);  Rush D. Robinett, III (Tijeras, New Mexico);  Wayne W. Weaver (Hancock, Michigan);  Madelyn G. Veurink (Albuquerque, New Mexico)
ABSTRACT One of the biggest challenges for all renewable energy sources (RES) is that they are variable power generators which will require reactive power or energy storage systems (ESS) to provide reliable power quality (ideally power factor of one) at the power grid generation side. The present invention is directed to a power packet network (PPN) for integrating wave energy converter (WEC) arrays into microgrids. Specifically, an array of WECs can be physically positioned such that the incoming regular waves will produce an output emulating an N-phase AC system such that the PPN output power is constant. ESS requirements are thereby minimized whilst maintaining grid stability with high power quality. This will enable RES integration onto a future smart grid for large-scale adoption and cost reduction while preserving high efficiency, reliability, and resiliency.
FILED Friday, February 18, 2022
APPL NO 17/675064
CURRENT CPC
Machines or Engines for Liquids
F03B 13/1885 (20130101) Original (OR) Class

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/48 (20130101)
H02J 3/381 (20130101)
H02J 2300/20 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266366 Li et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
ASSIGNEE(S) UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
INVENTOR(S) Fangxing Li (Knoxville, Tennessee);  Haoyuan Sun (Knoxville, Tennessee);  Christopher Sticht (Key Largo, Florida);  Srijib Mukherjee (Apex, North Carolina)
ABSTRACT Systems and methods herein provide for sinusoidal signal distortion monitoring and visualization via a Circular Trajectory Approach (CTA). In one embodiment, a system includes a differentiator operable to differentiate an input signal from a sinusoidal signal at substantially a same fundamental frequency of the input signal. The input signal comprising a sinusoidal waveform having distortions. The system also includes a processor operable to calculate a distance index from the input signal to a derivative of the input signal to reveal distortions in the input signal, and a display operable to display the distortions in the input signal.
FILED Thursday, February 23, 2023
APPL NO 18/113469
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 13/02 (20130101) Original (OR) Class
G01R 19/0053 (20130101)
G01R 23/167 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230266413 Shi et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S)
INVENTOR(S) Jing Shi (Riverside, California);  Junxue Li (Riverside, California)
ABSTRACT Systems and methods for spin-based detection of electromagnetic radiation at terahertz and sub-terahertz frequencies is provided. The detector can include a heterostructure and an electrical circuit. The heterostructure can include a first layer formed of an antiferromagnetic material (AFM) in contact with a second layer of a heavy metal (HM) and a third layer. The third layer can generate an effective field oriented approximately parallel to an easy axis of the first layer and approximately parallel to a propagation direction of electromagnetic radiation. The circuit can be in electrical communication with the second layer. The first layer can inject a spin current into the second layer in response to receipt of electromagnetic radiation having a sub-terahertz or terahertz frequency. The second layer can convert the injected spin current into a potential difference. The circuit can be configured to output a signal corresponding to the potential difference.
FILED Wednesday, April 26, 2023
APPL NO 18/307451
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/3586 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/075 (20130101)
G01R 33/1284 (20130101) Original (OR) Class

Electric solid-state devices not otherwise provided for
H10N 50/80 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267404 Villalobos et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S)
INVENTOR(S) Jesus Rene Villalobos (Mesa, Arizona);  Patrick Phelan (Scottsdale, Arizona);  Levi Siwek (Tempe, Arizona);  Keshawa Bandara (Tempe, Arizona);  Derall Riley (Tempe, Arizona)
ABSTRACT In accordance with embodiments disclosed herein, there are provided herein systems and methods for implementing aggregable, environment-controlled mini-containers for the efficient logistics of perishable products. For example, there is a system for providing efficient transportation logistics of dissimilar perishable products within a transportation unit, in which the system includes: multiple mini-containers, each being configurable to stack and aggregate to consume at least a portion of volume within the transportation unit; a Central Driving Unit (CDU) operable to provide services to each of the mini-containers to maintain the contents of each mini-container; a Central Control Unit (CCU) to receive sensor information from each of the mini-containers and further to issue control parameters for maintaining a specified atmosphere composition within each connected mini-container via the CDU, in which the CCU executes the control parameters for maintaining the specified atmosphere composition within each connected mini-container by activating actuators, in which the actuators manipulate valves at each mini-container, allowing for inflow and egress of atmospheric elements; and in which each of the multiple mini-containers constitute individual modular units configurable to form a single inter-connected and aggregated stack having a size which fits within the available volume of the transportation unit. In related embodiments, the CCU is further configured to transmit data on the status of the mini-containers to the outside world, such as transmitting status information to a remote storage location, or to the cloud, or directly to a centrally located data hub. Other related embodiments are disclosed.
FILED Tuesday, June 15, 2021
APPL NO 18/010357
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0832 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267658 Jimenez, JR. et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Edward Steven Jimenez, JR. (Albuquerque, New Mexico);  Cody M. Washburn (Albuquerque, New Mexico)
ABSTRACT A computer-implemented method of reconstructing boundaries from a computed tomography (CT) image dataset is provided. The method comprises receiving CT image data and applying a number of image filters to the CT image data. A numerical derivative is applied to the filtered CT image data to flatten and suppress non-edge regions that do not correspond to edges. Numerical derivative values are clipped to a specified range to reduce artifacts and noise, and an X-ray image is reconstructed according to the image filters and clipped numerical derivative values.
FILED Friday, February 18, 2022
APPL NO 17/675434
CURRENT CPC
Image Data Processing or Generation, in General
G06T 11/005 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268085 Taylor
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S)
INVENTOR(S) Chase N. Taylor (Idaho Falls, Idaho)
ABSTRACT A neutron moderator includes a porous metal hydride with channels within the porous metal hydride. Further, a method of regenerating a neutron moderator includes providing an at least partially depleted metal hydride article and introducing a hydrogen-containing gas into the at least partially depleted metal hydride article. The at least partially depleted metal hydride article includes channels. A nuclear reactor includes one or more neutron moderator regions in a core of a reactor, one or more fuel regions adjacent to the one or more neutron moderator regions, one or more heat transfer regions adjacent to the one or more fuel regions, control drums adjacent to the core, and a control rod adjacent to the core. One or more of the neutron moderator regions include a neutron moderator comprising a porous metal hydride article that has channels.
FILED Tuesday, February 21, 2023
APPL NO 18/171923
CURRENT CPC
Nuclear Reactors
G21C 7/10 (20130101)
G21C 7/24 (20130101) Original (OR) Class
G21C 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268094 Blanton et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Paul S. Blanton (Aiken, South Carolina);  Zenghu Han (Woodridge, Illinois);  Yung Y. Liu (Hinsdale, Illinois);  Ronald B. Pope (Waynesboro, Pennsylvania);  James M. Shuler (Germantown, Maryland)
ABSTRACT The invention provides a containment structure, the containment structure comprising a vessel with an upwardly facing opening defining a periphery; a lid in rotatable and slidable communication with the periphery; and a plurality of rods contained within the lid and in slidable communication with the periphery. Also provided is a method for sealing and unsealing a containment vessel defining a body with a longitudinal axis and a lid, the method comprising simultaneously moving the lid parallel to the longitudinal axis and orthogonal to the longitudinal axis.
FILED Friday, February 18, 2022
APPL NO 17/675604
CURRENT CPC
Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor
G21F 5/005 (20130101)
G21F 5/12 (20130101) Original (OR) Class
G21F 9/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268451 CARTER et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) Emily A. CARTER (Belle Mead, New Jersey);  Robert B. WEXLER (Philadelphia, Pennsylvania);  Sai Gautam GOPALAKRISHNAN (Hamilton, New Jersey)
ABSTRACT Disclosed herein are solar cells with kesterite-based absorbers that hold promise as a low-cost and durable technology to renewably produce electricity using solar energy conversion. The current state-of-the-art (SOA) for such kesterite solar cells is Cu2ZnSn(S,Se)4 and novel materials are required to suppress the formation bandgap-fluctuation- and charge-carrier-recombination-inducing defects and eventually to achieve solar cell efficiencies higher than the SOA. Three important material properties that govern the efficiency of a solar cell are the concentrations of performance-degrading defects, band gap, and chemical stability. Disclosed here is a stable material, specifically Cu2CdGe(S,Se)4, as a new candidate that can exhibit higher defect formation energies than Cu2ZnSnS4 and a nearly optimal bandgap, which can eventually result in higher solar-cell efficiencies in solar energy conversion.
FILED Monday, July 19, 2021
APPL NO 18/017544
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 19/002 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/068 (20130101)
H01L 31/0326 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268493 Kwon et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S)
INVENTOR(S) Yo Han Kwon (Atlanta, Georgia);  Elsa Reichmanis (Atlanta, Georgia)
ABSTRACT A composite electrode comprising a charge-conducting material, a charge-providing material bound to the charge-conducting material, and a plurality of single-walled carbon nanotubes bound to a surface of the charge-providing material. High-capacity electroactive materials that assure high performance are a prerequisite for ubiquitous adoption of technologies that require high energy/power density lithium (Li)-ion batteries, such as smart Internet of Things (IoT) devices and electric vehicles (EVs). Improved electrode performance and lifetimes are desirable. The disclosed electrode can have a Coulombic efficiency of 99% or greater, and a stable capacity retention after 100 cycles or more. Methods of making a composite electrode are disclosed.
FILED Monday, April 24, 2023
APPL NO 18/305470
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/386 (20130101) Original (OR) Class
H01M 4/0416 (20130101)
H01M 4/604 (20130101)
H01M 4/622 (20130101)
H01M 4/1399 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268502 LIPSON et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Albert L. LIPSON (Forest Park, Illinois);  Jessica L. DURHAM (Frankfort, Illinois)
ABSTRACT A stabilized lithium metal oxide cathode material comprises microparticles of lithium metal oxide in which individual particles thereof a core of lithium metal oxide and a coating of a different lithium metal oxide surrounding the core. There is an interface layer between the cores and the coatings in which there are gradients of metal ions in the direction of coating to core. The materials are made by a three stage process involving coprecipitating precursor metal hydroxide core particles at a controlled pH; coprecipitating a different metal hydroxide coating on the particles without controlling the pH; and then calcining the resulting coated precursor particles with lithium hydroxide to form the stabilized lithium metal oxide material.
FILED Wednesday, April 12, 2023
APPL NO 18/133925
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/366 (20130101)
H01M 4/0471 (20130101)
H01M 4/525 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 10/0568 (20130101)
H01M 10/0569 (20130101)
H01M 50/40 (20210101)
H01M 2300/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268568 Li et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S)
INVENTOR(S) Bin Li (Idaho Falls, Idaho);  Eric J. Dufek (Ammon, Idaho);  Parameswara R. Chinnam (Idaho Falls, Idaho);  Yulun Zhang (Salt Lake City, Utah)
ABSTRACT A method of operating an energy storage device comprises applying external pressure onto an electrochemical cell during charging and/or discharging. The cell comprises a sulfur-based cathode within a compressible vessel. An energy storage system may include plates and at least one electrochemical cell that includes—within a compressible vessel—a cathode, an anode, and an electrolyte. The cathode comprises a sulfur-based active material. In a method of assembling a system for operating an energy storage device, at least one electrochemical cell is disposed between a pair of plates and adjacent pressure sensor(s). A distance between the plates is fixed at which a measured pressure is within a range from greater than about 0 kPa to about 689 kPa above ambient pressure. The plate-separation distance is maintained while charging or discharging the electrochemical cell(s).
FILED Friday, July 16, 2021
APPL NO 18/005567
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/623 (20130101)
H01M 4/625 (20130101)
H01M 10/44 (20130101) Original (OR) Class
H01M 10/0481 (20130101)
H01M 2004/021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268574 Dai et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S)
INVENTOR(S) Sheng Dai (Knoxville, Tennessee);  Huimin Luo (Knoxville, Tennessee);  Bishnu P. Thapaliya (Knoxville, Tennessee);  Tao Wang (Knoxville, Tennessee)
ABSTRACT A method for processing spent nickel-based cathode material useful in lithium-based batteries, the method comprising: (i) producing an initial mixture containing the spent nickel-based cathode material and a molten salt system comprising cations and anions, wherein the cations comprise lithium cations; (ii) heating the initial mixture to a temperature of 700° C. to 900° C. for at least 1 hour to produce a relithiated cathode material; and (iii) washing the relithiated cathode material to remove any residual salt. In a further method, the cations comprise nickel and lithium cations and the anions comprise chloride or bromide anion in combination with at least one of nitrate, sulfate, and carbonate anions in further combination with hydroxide anion, wherein the method results in upcycling of the nickel-based cathode material to produce a version of said relithiated cathode material having a greater nickel content.
FILED Wednesday, February 22, 2023
APPL NO 18/112646
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/58 (20130101)
H01M 4/0471 (20130101)
H01M 4/525 (20130101)
H01M 10/052 (20130101)
H01M 10/54 (20130101) Original (OR) Class
H01M 2004/021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268678 KHALIGH et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Fariborz MUSAVI (Redmond, Washington);  UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
ASSIGNEE(S)
INVENTOR(S) Alireza KHALIGH (Arlington, Virginia);  Fariborz MUSAVI (Redmond, Washington)
ABSTRACT In some embodiments, systems and methods for connector assembly for use with an AC or DC power interface of a power conversion device, such as a converter and an inverter, are provided. The connector assembly can include a circuit board, a power connector, and a pin. The power connector can have a base configured to be secured relative to the circuit board and define a first channel extending through the power connector along a first channel axis. The first pin can have a first pin body that extends along a first pin axis and a first connection element that extends along the first pin axis from the first pin body to a first terminal end that is skewed relative to the first pin axis.
FILED Friday, April 28, 2023
APPL NO 18/309337
CURRENT CPC
Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 12/7082 (20130101) Original (OR) Class
H01R 13/2471 (20130101)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 40/32 (20141201)
H02S 40/36 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268704 Stoll et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
ASSIGNEE(S)
INVENTOR(S) Trevor T. Stoll (Excelsior Springs, Missouri);  Michael E. Auxier (Olathe, Kansas)
ABSTRACT A demating device configured to demate an electrical connector assembly having a first connector and a second connector is provided. The demating device may include a first separating member, a second separating member, and a gripping assembly. Actuation of the first separating member and the second separating member towards one another drives the jaws of the gripping assembly together, therein allowing secure gripping of the electrical connector assembly via the demating device for separation of the first and second connectors.
FILED Wednesday, February 23, 2022
APPL NO 17/678637
CURRENT CPC
Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 13/633 (20130101)
H01R 43/26 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268705 Hatch et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) Honeywell Federal Manufacturing & Technologies, LLC (Kansas City, Missouri)
ASSIGNEE(S)
INVENTOR(S) Stephen McGarry Hatch (Blue Springs, Missouri);  James Alexander Zandstra (Long Beach, California)
ABSTRACT Electrical connector assembly devices, systems, and methods including a demating device configured to separate a first connector and a second connector of an electrical connector assembly. The demating device includes a housing body, a drive assembly including: a drive lever, a trigger configured to push against the drive lever, a drive assembly rod, and a spring mounted around the drive assembly rod; and a demating assembly including: a movable plate having at least two sides, wherein each of the two sides includes at least two prongs; a stationary plate having at least two sides, wherein each of the two sides includes at least two prongs; and a rotary actuator configured to rotate the movable plate.
FILED Wednesday, February 23, 2022
APPL NO 17/678680
CURRENT CPC
Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 13/635 (20130101)
H01R 13/6335 (20130101)
H01R 43/22 (20130101)
H01R 43/26 (20130101) Original (OR) Class
H01R 43/205 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268709 Diroll
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S)
INVENTOR(S) Benjamin Diroll (Chicago, Illinois)
ABSTRACT Optical gain mediums are required for lasing devices and high intensity optical systems across a wide range of applications. A method for achieving optical gain includes an optical gain medium having colloidal quantum fountains includes providing pump radiation to the gain medium. The electrons of the colloidal quantum fountains are promoted from a valence band to an excited state in a conduction band of the colloidal quantum fountains. Seed radiation is provided to the gain medium and electrons of the quantum fountains are de-excited by the seed radiation through stimulated emission from the excited state to a lower energy state of the conduction band, thereby providing optical gain.
FILED Monday, February 21, 2022
APPL NO 17/676307
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/169 (20130101)
H01S 3/094096 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268721 Yang et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
National Science Foundation (NSF)
APPLICANT(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma);  Sandia National Laboratories (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) Rui Q. Yang (Norman, Oklahoma);  John F. Klem (Albuquerque, New Mexico)
ABSTRACT An ICL comprises: a plurality of IC stages, wherein each of the IC stages comprises: a hole injector; an electron injector; an active region coupled to the hole injector and the electron injector and comprising a first layer, wherein the first layer comprises a first material, and wherein the first material comprises InAsP or AlInAsP; a conduction band running through the hole injector, the electron injector, and the active region; and a valence band running through the hole injector, the electron injector, and the active region.
FILED Monday, February 13, 2023
APPL NO 18/168337
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/3402 (20130101) Original (OR) Class
H01S 5/3422 (20130101)
H01S 5/34306 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268882 GOSTEIN et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Michael GOSTEIN (Austin, Texas);  William STUEVE (Austin, Texas)
ASSIGNEE(S)
INVENTOR(S) Michael GOSTEIN (Austin, Texas);  William STUEVE (Austin, Texas)
ABSTRACT In one respect, disclosed is a device comprising terminals or connections configured to connect to a first associated PV module, I-V measurement circuitry coupled to said terminals or connections and configured to measure I-V data of said first associated PV module, communication circuitry configured to communicate with at least one external device, and a processor coupled to said I-V measurement circuitry and to said communication circuitry, wherein said processor is configured to receive external data via said communication circuitry from said at least one external device, and wherein said processor is configured to determine a relative performance metric based at least upon said I-V data of said first associated PV module and said external data. In another respect, disclosed is a system comprising a first device configured to measure first I-V data of a first associated PV module and a second device configured to measure second I-V data of a second associated PV module, wherein said first device may be configured to receive said second I-V data and to determine a relative performance metric based at least upon said second I-V data and said first I-V data.
FILED Tuesday, April 04, 2023
APPL NO 18/130558
CURRENT CPC
Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 50/15 (20141201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 20230263164 Bowden et al.
FUNDED BY
National Science Foundation (NSF)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
ASSIGNEE(S) UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
INVENTOR(S) Ned B. Bowden (Iowa City, Iowa);  Justin M. CARTER (Iowa City, Iowa);  Eric M. BROWN (Iowa City, Iowa);  Nimesh RANASINGHE (Iowa City, Iowa);  Arjun PAUDEL (Iowa City, Iowa);  Erin E. IRISH (Iowa City, Iowa)
ABSTRACT The invention provides a compound of formula (I): wherein X, Y Z, R1, R2, and X+ have any of the values described in the specification. The compounds are useful to increase plant growth and/or to increase harvest yield.
FILED Monday, August 30, 2021
APPL NO 18/024034
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 57/12 (20130101) Original (OR) Class
A01N 57/16 (20130101)

Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations
A01P 21/00 (20210801)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/06 (20130101)
C07F 9/6578 (20130101)
C07F 9/657118 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263176 Farcuh et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S)
INVENTOR(S) Macarena Farcuh (Silver Spring, Maryland);  Rohan Tikekar (Silver Spring, Maryland);  Joseph H. Sullivan (Brookeville, Maryland);  Yixin Cai (College Park, Maryland);  Abraham Moses Monteymayor (Washington, District of Columbia)
ABSTRACT Provided herein are methods relating to ultraviolet irradiation of apples to improve their color and safety. The methods allow harvesting apples at optimum maturity, without having to delay waiting for color. The methods result in a significant increase in red skin coloration and suppression of L. monocytogenes without impairing fruit quality attributes during commercial storage.
FILED Friday, February 03, 2023
APPL NO 18/164325
CURRENT CPC
Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products
A23B 7/015 (20130101) Original (OR) Class

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 3/28 (20130101)
A23L 19/03 (20160801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263190 Ulmasov et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) COVERCRESS INC. (ST. LOUIS, Missouri);  BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (Normal, Illinois);  REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S)
INVENTOR(S) Tim Ulmasov (St. Louis, Missouri);  Gary Hartnell (St. Peters, Missouri);  John C. Sedbrook (Bloomington, Illinois);  Michael David Marks (Roseville, Minnesota);  Ratan Chopra (St. Louis, Missouri);  Maliheh Esfahanian (Stanford, California)
ABSTRACT Pennycress seed, seed lots, and seed meal having reduced fiber content and improved suitability for use in producing animal feed are provided.
FILED Thursday, March 16, 2023
APPL NO 18/185195
CURRENT CPC
Fodder
A23K 10/30 (20160501) Original (OR) Class
A23K 20/158 (20160501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265450 Ulmasov et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) COVERCRESS INC. (ST. LOUIS, Missouri);  BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (Normal, Illinois);  REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S)
INVENTOR(S) Tim Ulmasov (St. Louis, Missouri);  John C. Sedbrook (Bloomington, Illinois);  Michael David Marks (Roseville, Minnesota);  Ratan Chopra (St. Louis, Missouri)
ABSTRACT Pennycress (Thlaspi arvense) seed, seed lots, seed meal, and compositions with reduced glucosinolate content as well as plants that yield such seed, seed lots, seed meal, and compositions are provided. Methods of making and using the pennycress plants and/or seed that provide such seed, seed lots, seed meal, and compositions are also provided.
FILED Thursday, March 16, 2023
APPL NO 18/185179
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 5/10 (20130101)
A01H 6/20 (20180501)

Fodder
A23K 10/30 (20160501)
A23K 40/10 (20160501)
A23K 50/10 (20160501)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8245 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265529 Singh et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida);  The United State of America, as presented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Prashant Singh (Tallahassee, Florida);  Joseph M. Bosilevac (Clay Center, Nebraska)
ABSTRACT Disclosed herein are methods and kits for quantifying the presence of a microorganism in a sample. Specifically, disclosed are methods for quantifying a pathogen in a sample, such as a food sample, to determine if the levels of pathogen present in the sample are within an acceptable range.
FILED Friday, November 11, 2022
APPL NO 18/054778
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 20230263398 Tang et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland);  THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Cha-Min Tang (Wayne, Pennsylvania);  Joseph Schmitt (Cupertino, California)
ABSTRACT An apparatus provided for detecting tooth pulp vitality includes a handle, a pivot and a caliper. A pair of fiber optic lines pass through an interior of the handle, the pivot and the caliper. One of the fiber optic lines is a source line with a connector at an end of the source line and another of the fiber optic lines is a detector line with a connector at an end of the detector line. The source line is single mode in the handle and the detector line is multi mode. A system is also provided for detecting tooth pulp vitality that includes the apparatus. Additionally, a method is provided for detecting tooth pulp vitality that employs the apparatus.
FILED Friday, April 21, 2023
APPL NO 18/304711
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0066 (20130101)
A61B 5/0088 (20130101) Original (OR) Class
A61B 5/0261 (20130101)
A61B 5/682 (20130101)
A61B 5/4547 (20130101)
A61B 2090/3614 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263943 Myung et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California);  The United States Government as represented by the Department of Veterans Affairs (NW Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) David Myung (Saratoga, California);  Fang Chen (Stanford, California);  Gabriella Fernandes-Cunha (Palo Alto, California);  Sarah Hull (Stanford, California);  Sarah Heilshorn (Mountain View, California);  Christopher Lindsay (San Mateo, California);  Christopher Madl (Los Altos, California);  Hyun Jong Lee (Gyeonggi-do, South Korea)
ABSTRACT Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined hydrogel structure in situ, including interpenetrating (IPN) and semi-IPN hydrogels.
FILED Thursday, April 29, 2021
APPL NO 17/997097
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/142 (20130101)
A61F 2210/0085 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/26 (20130101)
A61L 27/52 (20130101) Original (OR) Class
A61L 2400/06 (20130101)
A61L 2430/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265121 Marx et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) Duke University (Durham, North Carolina);  Department of Veterans Affairs (Baltimore, Maryland)
ASSIGNEE(S)
INVENTOR(S) Christine Marx (Durham, North Carolina);  Robert Mook (Durham, North Carolina)
ABSTRACT The present disclosure provides modified neuroactive steroids. The modified neuroactive steroids may comprise, consist of, or consist essentially of a therapeutic agent and/or a modifying moiety. The modified neuroactive steroid can have modified characteristics as compared to native neuroactive steroids that do not include a modifying moiety and/or therapeutic agent. The modified neuroactive steroid may be, for example, modified pregnenolone, pregnenolone metabolites, allopregnanolone, and/or allopregnanolone metabolites. The modified neuroactive steroids can be used to treat, prevent and/or ameliorating a phenotypic state of interest in a subject.
FILED Tuesday, June 21, 2022
APPL NO 17/807891
CURRENT CPC
Steroids
C07J 7/001 (20130101) Original (OR) Class
C07J 7/007 (20130101)
C07J 7/0045 (20130101)
C07J 13/007 (20130101)
C07J 31/006 (20130101)
C07J 41/0005 (20130101)
C07J 41/005 (20130101)
C07J 43/003 (20130101)
C07J 51/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 20230263565 Borsic
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) NE Scientific, LLC (Boston, Massachusetts)
ASSIGNEE(S) NE Scientific, LLC (Boston, Massachusetts)
INVENTOR(S) Andrea Borsic (Torino, Italy)
ABSTRACT A system for ablation treatment of tissues including at least one tissue ablation device, an ablation device controller communicatively connected to the at least one tissue ablation device, and an imaging component, wherein the imaging component is configured to capture a captured image that includes a representation of the tissue ablation device. The system further including an ablation device identification component configured to receive the captured image, generate a plurality of region proposals from the captured image, extract a plurality of feature vectors from the plurality of region proposals, determine a class for each region proposal of the plurality of region proposals, and determine the position and orientation of the tissue ablation device as a function of the classes for each region proposal.
FILED Thursday, August 18, 2022
APPL NO 17/890839
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/1206 (20130101) Original (OR) Class
A61B 18/1815 (20130101)
A61B 34/25 (20160201)
A61B 90/37 (20160201)
A61B 2018/00577 (20130101)
A61B 2018/1861 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230263932 Brown et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Embody, Inc. (Norfolk, Virginia)
ASSIGNEE(S)
INVENTOR(S) Robert S. Brown (Norfolk, Virginia);  Caitlin Harclerode (Norfolk, Virginia);  Nardos Sori (Norfolk, Virginia);  Michael P. Francis (Norfolk, Virginia);  Nicholas Thayer (Morrisville, North Carolina)
ABSTRACT An implantable biopolymer scaffold includes at least one braided strand comprising high strength collagen fibers and synthetic fibers, wherein the collagen fibers have a greater cross-sectional deform ability than the synthetic fibers.
FILED Thursday, February 09, 2023
APPL NO 18/167051
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 17/08 (20130101)
A61L 17/14 (20130101) Original (OR) Class
A61L 17/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230265516 GARCIA et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) UNIVERSITY OF ARIZONA, ARIZONA BOARD OF REGENTS (Tucson, Arizona)
ASSIGNEE(S)
INVENTOR(S) Joe G.N. GARCIA (Tucson, Arizona);  Mohamed n. AHMED (Tucson, Arizona)
ABSTRACT A method of identifying single nucleotide polymorphisms (SNPs) within the NAMPT promoter that are associated with an inflammatory condition, such as cardiac ischemia, traumatic brain injury, cancer, chorioamnionitis, nonalcoholic steatohepatitis (NASH), or renal fibrosis. Also provided are methods of diagnosing and treating such inflammatory condition in a subject.
FILED Friday, August 06, 2021
APPL NO 18/040976
CURRENT CPC
Peptides
C07K 16/40 (20130101)
C07K 2317/565 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 20230265497 Dhingra et al.
FUNDED BY
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
Finding Engineering-Linked Indicators (FELIX)
APPLICANT(S) Mission Bio, Inc. (South San Francisco, California)
ASSIGNEE(S)
INVENTOR(S) Dalia Dhingra (South San Francisco, California);  David Ruff (South San Francisco, California)
ABSTRACT Disclosed herein is a single-cell analysis workflow involving whole genome amplification for developing single-cell whole genome DNA libraries. The single-cell analysis workflow involves encapsulating and lysing cells in individual droplets and releasing genomic DNA from chromatin within the droplet. Transposases access the released genomic DNA and insert adaptor sequences into the cleaved nucleic acid fragments, thereby generating tagmented genomic DNA fragments that span the whole genome. Tagmented genomic DNA undergo nucleic acid amplification and sequencing for generating single-cell whole genome DNA libraries.
FILED Friday, March 19, 2021
APPL NO 17/912689
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101)
B01L 7/52 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6869 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230267356 MONROE et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S)
INVENTOR(S) Christopher MONROE (Ellicott City, Maryland);  Marko CETINA (College Park, Maryland);  Norbert LINKE (Stevenson, Maryland);  Shantanu DEBNATH (College Park, Maryland)
ABSTRACT The disclosure describes various aspects of optical control of atomic quantum bits (qubits) for phase control operations. More specifically, the disclosure describes methods for coherently controlling quantum phases on atomic qubits mediated by optical control fields, applying to quantum logic gates, and generalized interactions between qubits. Various attributes and settings of optical/qubit interactions (e.g., atomic energy structure, laser beam geometry, polarization, spectrum, phase, background magnetic field) are identified for imprinting and storing phase in qubits. The disclosure further describes how these control attributes are best matched in order to control and stabilize qubit interactions and allow extended phase-stable quantum gate sequences.
FILED Monday, April 24, 2023
APPL NO 18/305954
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Optical Computing Devices;
G06E 1/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 20230266237 GAO et al.
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S) NOAA, US DEPARTMENT OF COMMERCE (Silver Spring, Maryland)
ASSIGNEE(S)
INVENTOR(S) RU-SHAN GAO (BOULDER, Colorado);  STEVEN CICIORA (SUPERIOR, Colorado)
ABSTRACT Embodiments of the present invention relate to an apparatus for detecting ozone in ambient air, including an absorption cell with a bounded chamber for receiving air sample for analysis, a light source positioned to transmit light through absorption cell, a detector positioned to measure the attenuation of light passing through absorption cell, a pumping system for transporting ambient air into chamber and then reversing direction to transport ozone-free air into the absorption cell for purging the chamber, a scrubber positioned downstream from outlet port of the absorption cell to remove ozone from sample air exiting the absorption cell, a relative humidity (RH) equalizer for controlling humidity of sample air exiting absorption cell such that the sample entering scrubber has relatively the same humidity as ambient air, and a data system for digitizing and processing output from detector.
FILED Wednesday, January 04, 2023
APPL NO 18/093008
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/24 (20130101)
G01N 1/2273 (20130101)
G01N 1/4077 (20130101)
G01N 21/33 (20130101) Original (OR) Class
G01N 2001/245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 20230264504 Zlotnick et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Joel Zlotnick (Arlington, Virginia);  Tyra McConnell (Knoxville, Maryland);  Traci Moran (Rockville, Maryland);  Jordan Brough (Leesburg, Virginia);  Troy Eberhardt (Centreville, Virginia);  Elizabeth Gil (Bristow, Virginia)
ABSTRACT A security system for an article of manufacture includes one or more first planchettes and one or more second planchettes included in the article. The first planchettes luminesce under a first frequency of light and the second planchettes luminesce under a second frequency of light with at least one of three characteristics. First, the first frequency is different from the second frequency, the first planchettes do not luminesce under the second frequency of light, and the second planchettes do not luminesce under the first frequency of light. Second, the first planchettes luminesce at a first color under the first frequency of light and the second planchettes luminesce at a second color different from the first color under the second frequency of light. Third, the first planchettes reflect a first pattern under the first frequency of light and the second planchettes reflect a second pattern under the second frequency of light.
FILED Thursday, January 26, 2023
APPL NO 18/102002
CURRENT CPC
Printing, Duplicating, Marking, or Copying Processes; Colour Printing,
B41M 3/14 (20130101) Original (OR) Class

Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus
B42D 25/20 (20141001)
B42D 25/355 (20141001)
B42D 25/387 (20141001)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Treasury (TREASURY) 

US 20230264510 Rich et al.
FUNDED BY
Department of the Treasury (TREASURY)
Bureau of Engraving and Printing (BEP)
APPLICANT(S) WAVEFRONT TECHNOLOGY, INC. (Paramount, California)
ASSIGNEE(S)
INVENTOR(S) Christopher Chapman Rich (Rancho Palos Verdes, California);  Joel Mikael Petersen (Valley Village, California);  Roger Winston Phillips (Santa Rosa, California);  John Michael Tamkin (Pasadena, California)
ABSTRACT An optical device includes an array of lenses and a plurality of segments disposed under the array of lenses. The plurality of segments corresponds to a plurality of images. Upon tilting the device at different viewing angle, the array of lenses presents images sequentially. In some examples, individual ones of the segments can comprise specular reflecting, transparent, diffusely reflecting, and/or diffusely transmissive features. In some examples, individual ones of the segments can comprise transparent and non-transparent regions. The images can produce one or more optical effects.
FILED Thursday, August 25, 2022
APPL NO 17/822413
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/08 (20130101)
B32B 3/30 (20130101)
B32B 7/06 (20130101)
B32B 27/08 (20130101)
B32B 27/32 (20130101)
B32B 27/36 (20130101)
B32B 27/285 (20130101)
B32B 27/302 (20130101)
B32B 27/304 (20130101)
B32B 27/365 (20130101)
B32B 2250/24 (20130101)
B32B 2255/20 (20130101)
B32B 2255/26 (20130101)
B32B 2255/28 (20130101)
B32B 2255/205 (20130101)
B32B 2307/40 (20130101)
B32B 2307/41 (20130101)
B32B 2307/204 (20130101)
B32B 2307/402 (20130101)
B32B 2307/408 (20130101)
B32B 2307/412 (20130101)
B32B 2307/422 (20130101)
B32B 2307/732 (20130101)
B32B 2307/4023 (20130101)
B32B 2307/4026 (20130101)
B32B 2425/00 (20130101)

Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus
B42D 25/21 (20141001)
B42D 25/324 (20141001)
B42D 25/328 (20141001)
B42D 25/351 (20141001) Original (OR) Class
B42D 25/373 (20141001)
B42D 25/378 (20141001)

Special Designs or Pictures
B44F 1/045 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/0056 (20130101)
G02B 27/06 (20130101)
G02B 30/27 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 20230264986 Sahu et al.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S) THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (Charlotte, North Carolina)
ASSIGNEE(S)
INVENTOR(S) Abhispa Sahu (Charlotte, North Carolina);  Jordan C. Poler (Charlotte, North Carolina)
ABSTRACT Nanocomposite materials are described herein which, in some embodiments, are employed as separation media for removal of various contaminants from water sources, including heavy metals, PFAS and/or NOM. In some embodiments, a nanocomposite material comprises oligomeric chains or polymeric chains covalently attached to surfaces of fluorographite at sites of defluorination. In another aspect, nanocomposite materials based on cellulose nanofibers are described herein. In some embodiments, a nanocomposite material comprises oligomeric chains or polymeric chains covalently attached to surfaces of cellulose nanofibers.
FILED Friday, August 13, 2021
APPL NO 18/020694
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/24 (20130101)
B01J 20/205 (20130101)
B01J 20/265 (20130101)
B01J 20/3255 (20130101)
B01J 20/3293 (20130101)
B01J 20/28016 (20130101)
B01J 2220/46 (20130101)
B01J 2220/4806 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/42 (20130101) Original (OR) Class
C02F 2001/422 (20130101)
C02F 2001/425 (20130101)
C02F 2101/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 20230264827 GURUSWAMY
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Guru Pillappa GURUSWAMY (Sunnyvale, California)
ABSTRACT A system can include a controller that can generate a query request in response to an instantaneous roll angle of a vertical take off and landing (VTOL) aircraft being equal to or greater than a roll angle threshold. The instantaneous roll angle being equal to or greater than the roll angle threshold can indicate that the VTOL aircraft has deviated or is about to deviate from a current stable aircraft state. A database can provide propeller control data identifying a propeller speed profile for at least one propeller of the VTOL aircraft in response to the query request. The database can store different propeller speed profiles for at least some propellers of the VTOL aircraft for respective roll angles. The controller can cause the at least one propeller of the VTOL aircraft to rotate at the propeller speed to return the VTOL aircraft to the stable aircraft state.
FILED Friday, February 17, 2023
APPL NO 18/171268
CURRENT CPC
Aeroplanes; Helicopters
B64C 29/0025 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 31/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 20230267408 Dixon et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Robert E. Dixon (Washington, District of Columbia);  Ryan Luckay (Washington, District of Columbia)
ABSTRACT A receptacle for detecting delivery and retrieval events has a door sensor, an item sensor, a scanner, and a control unit for operating the sensors, and transmitting the sensor information for processing and analysis. A system can determine whether an event was a delivery or retrieval event based on sensor information and item tracking information. A system can further include an item configured to interact with a computing device.
FILED Thursday, February 09, 2023
APPL NO 18/166912
CURRENT CPC
Household or Table Equipment
A47G 29/141 (20130101)
A47G 2029/145 (20130101)
A47G 2029/146 (20130101)
A47G 2029/149 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/1413 (20130101)
G06K 19/06028 (20130101)
G06K 2019/06253 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0836 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 20230265762 Krumanaker et al.
FUNDED BY
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S)
INVENTOR(S) Matthew Lee Krumanaker (Blue Ash, Ohio);  Thomas Joseph Lipinski (Monroe, Ohio)
ABSTRACT A turbine engine comprising an engine core, a plurality of circumferentially arranged vanes, and a floating seal. The plurality of circumferentially arranged vanes forming an upper band and a lower band. The floating seal being carried by at least one respective vane of the plurality of circumferentially arranged vanes. The floating seal having a ring and at least one dynamic seal.
FILED Thursday, December 01, 2022
APPL NO 18/072921
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 11/025 (20130101) Original (OR) Class

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/28 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/55 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 20230268312 Wallace et al.
FUNDED BY
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Peter M. Wallace (Newfields, New Hampshire);  Daniel E. Mendoza (Leominster, Massachusetts)
ABSTRACT A pressure collet that operably engages with a die in which the pressure collet is configured to land on predetermined positions of the die without damaging said die, a perform, or a heat spreader during a reflow process. The pressure collet further comprises a plate that has a mounting surface and a plurality of contact pads that operably engages with the mounting surface of the plate. The plurality of contact pads is configured to apply pressure to predetermined positions of a die without the mounting surface of the plate contacting the die during a reflow process. The plate of the pressure collet is also formed of a first material and the plurality of contact pads are formed of a second material different than the first material.
FILED Friday, February 18, 2022
APPL NO 17/675600
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 1/0012 (20130101)
B23K 1/0016 (20130101)
B23K 3/087 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 24/75 (20130101) Original (OR) Class
H01L 24/81 (20130101)
H01L 24/83 (20130101)
H01L 2224/7532 (20130101)
H01L 2224/75312 (20130101)
H01L 2224/75318 (20130101)
H01L 2224/81203 (20130101)
H01L 2224/81815 (20130101)
H01L 2224/83203 (20130101)
H01L 2224/83815 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT APPLICATION DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Thursday, August 24, 2023.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract is presented as it appears on the patent.

FILED
The date the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230824.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital