FedInvent™ Patent Applications
Application Details for Thursday, September 28, 2023
This page was updated on Thursday, September 28, 2023 at 05:50 PM GMT
Department of Health and Human Services (HHS)
| US 20230301510 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Haichong Zhang (Shrewsbury, Massachusetts); Yu Chen (Worcester, Massachusetts); Xihan Ma (Worcester, Massachusetts) |
| ABSTRACT | A robotically driven OCT scanning and imaging system provides a 3-dimensional (3D) image rendering based on a 2-dimensional (2D) surface traversal of a Region of Interest (ROI) for immediate depiction of tissue health with an accuracy and portability not available with conventional imaging approaches. A comprehensive scan over the surface of the ROI ensures complete coverage, and a signal indicative of attenuation of the optical scan indicates penetration of the OCT stimulus. The received signal for each location is aggregated, or “stitched” together with the signal received from adjacent locations to provide a full mapping of the scanned region, and rendered as a color or shading map for showing anomalies or sudden variances in tissue health. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/125823 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) Original (OR) Class A61B 34/30 (20160201) Image Data Processing or Generation, in General G06T 17/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301513 | DHALLA et al. |
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| FUNDED BY |
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| APPLICANT(S) | Joseph IZATT (Durham, North Carolina); DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Al-Hafeez Z. DHALLA (Durham, North Carolina); Franklin WEI (Durham, North Carolina); Anthony N. KUO (Durham, North Carolina); Jianwei D. LI (Durham, North Carolina); Joseph A. IZATT (Durham, North Carolina) |
| ABSTRACT | An imaging system for performing a hybrid spiral scan pattern includes a scanner, a scanner controller in communication with the scanner to direct the scanner to perform a hybrid spiral scan pattern, wherein the hybrid spiral scan pattern includes a constant angular velocity (CAV) spiral scan pattern, a constant linear velocity (CLV) spiral scan pattern, and a transition spiral scan pattern. In some cases, the imaging system further includes a light source, and the scanner is positioned to receive light from the light source and direct the light to an object. In some cases, the imaging system further includes at least one position sensor for detecting actual positions of the scanner during the hybrid spiral scan pattern. In some cases, the imaging system further includes an image processor coupled to receive position data detected by the at least one position sensor and produce an image. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 18/020784 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) Original (OR) Class A61B 5/0035 (20130101) A61B 5/0097 (20130101) A61B 2576/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301555 | MUJEEB-U-RAHMAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | INTEGRATED MEDICAL SENSORS, INC. (IRVINE, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MUHAMMAD MUJEEB-U-RAHMAN (IRVINE, California); MEISAM HONARVAR NAZARI (IRVINE, California); MEHMET SENCAN (TUSTIN, California) |
| ABSTRACT | There is provided a glucose sensor system comprising: a transmitter (2) for containing a battery (212), the transmitter being for placement on top of patient skin; a transcutaneous connector (3) comprising at least one conductive path; and an implantable monolithic integrated circuit (1) for placement beneath the patient skin, wherein the implantable monolithic integrated circuit comprises a potentiostat and an electrochemical sensing element; wherein the potentiostat is electrically coupled to the transmitter (2) via the transcutaneous connector (3), and the electrochemical sensing element is configured to sense glucose concentration and generate an electrical signal representative of the glucose concentration, and wherein the potentiostat is electrically connected to the electrochemical sensing element. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/993516 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/6848 (20130101) A61B 5/14532 (20130101) Original (OR) Class A61B 5/14865 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230301595 — MULTIMODAL, MULTILAYERED SOFT ELECTRONICS IN ADVANCED DEVICES AND APPLICATIONS OF SAME
| US 20230301595 | Rogers et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John A. Rogers (Wilmette, Illinois); Roozbeh Ghaffari (Cambridge, Massachusetts); Igor Efimov (Arlington, Virginia); Mengdi Han (Evanston, Illinois) |
| ABSTRACT | An electronic system for multimodal diagnostic measurements and therapeutic interventions includes a plurality of element network layers vertically stacked one with another on a flexible substrate, each element network layer being bi-axially stretchable and comprising a plurality of elements configured in an addressable, interconnected array formed in a multilayered structure and operably performing a distinct function. The electronic system is a multimodal, multiplexed soft electronic system in a multilayered configuration that supports capabilities ranging from high-density spatiotemporal mapping of temperature, pressure and electrophysiological parameters, to options in programmable high-density actuation of thermal inputs and/or electrical stimulation, drug elution, radio frequency ablation, and/or irreversible electroporation ablation. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 18/021418 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/263 (20210101) A61B 5/287 (20210101) A61B 5/367 (20210101) A61B 5/02055 (20130101) A61B 5/4839 (20130101) A61B 5/6853 (20130101) Original (OR) Class A61B 5/6885 (20130101) A61B 18/1492 (20130101) A61B 2562/066 (20130101) A61B 2562/125 (20130101) A61B 2562/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301787 | Guo et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Ting Guo (Cambridge, Massachusetts); John Patrick Fisher (Kensington, Maryland); Hannah Baker (Baltimore, Maryland); Max Jonah Lerman (Silver Spring, Maryland); Robert Choe (Arlington, Virginia) |
| ABSTRACT | An implantable acellular polymeric scaffold device functionalized with aggrecan is provided. Also provided are methods of fabricating a polymeric scaffold device, including methods of fabricating the scaffold device via 3D printing. Methods of treating a cartilage defect in a subject in need thereof comprise application of the disclosed scaffold device in combination with microfracture procedures. A specialized lid for a centrifugation well plate is also provided. |
| FILED | Friday, May 19, 2023 |
| APPL NO | 18/320760 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/30756 (20130101) Original (OR) Class A61F 2002/30766 (20130101) A61F 2002/30985 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301912 | Franz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Annaliese Franz (Davis, California); Angel Cobo (Davis, California); Leah Thompson (Davis, California); David Coppage (Davis, California) |
| ABSTRACT | This disclosure provides silyl lipid molecules in which one or more carbon-to-carbon double bonds in the lipophilic portion is substituted with a silicon atom. Guidance is provided by which the reader may make silyl lipid molecules from molecular building blocks, and then incorporate silyl lipid molecules into lipid nanoparticles (LNPs). The silyl LNPs can be used as carriers of pharmaceutical agents. Flexible steric and substitution patterns of silyl groups in the LNPs give the user a way to fine-tune physicochemical properties, achieving improved stability and clinical efficacy. This technology is useful for immunization or genetic therapy, such as the preparation and administration of RNA vaccines for protection against the virus that causes COVID-19. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/159010 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 31/7105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301913 | FRANZ et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the Univesity of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Annaliese FRANZ (Davis, California); Angel COBO (Davis, California); Leah THOMPSON (Davis, California); David COPPAGE (Davis, California) |
| ABSTRACT | This disclosure provides silyl lipid molecules in which one or more carbon-to-carbon double bonds in the lipophilic portion is substituted with a silicon atom. Guidance is provided by which the reader may make silyl lipid molecules from molecular building blocks, and then incorporate silyl lipid molecules into lipid nanoparticles (LNPs). The silyl LNPs can be used as carriers of pharmaceutical agents. Flexible steric and substitution patterns of silyl groups in the LNPs give the user a way to fine-tune physicochemical properties, achieving improved stability and clinical efficacy. This technology is useful for immunization or genetic therapy, such as the preparation and administration of RNA vaccines for protection against the virus that causes COVID-19. |
| FILED | Wednesday, May 10, 2023 |
| APPL NO | 18/315011 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 31/7105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301931 | LEONG et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kam W. LEONG (New York, New York); Divya BHANSALI (New York, New York); Tianyu LI (New York, New York) |
| ABSTRACT | The nanoparticulate system for delivering treating agents may be used, for example, for treating inflammation, or for treating cancer, such as oral cancer, and associated inflammation The system used in this manner provides a solution to oral cancer and its associated metastasis by providing a targeted therapy to deliver chemotherapeutics. The nanoparticulate system is in the form of cholesterol-modified polyamidoamine-G3 nanoparticles (PAMAM-Chol NPs), which are used as a carrier for at least one drug. The at least one drug may include at least one cancer drug, at least one corticosteroid, at least one anabolic steroid, at least one hormone (natural or synthetic), and combinations thereof. |
| FILED | Monday, August 16, 2021 |
| APPL NO | 18/041618 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 9/5146 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301949 | HAMMOCK et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); CHIBA UNIVERSITY (CHIBA, Japan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bruce D. HAMMOCK (Davis, California); Sung Hee HWANG (Woodland, California); Jun YANG (Davis, California); Kenji HASHIMOTO (Chiba, Japan) |
| ABSTRACT | Provided herein are methods of preventing, reducing, ameliorating, mitigating, inhibiting, treating and/or reversing a neurodevelopmental disorder related to prenatal maternal immune activation in an individual in need thereof comprising administering to said individual an agent that increases the level of epoxy-fatty acids wherein said individual experienced maternal immune activation one or more times during gestation. Also provided herein are methods of preventing, reducing, ameliorating, mitigating, inhibiting treating and/or reversing schizophrenia or autism spectrum disorder an individual comprising administering to said individual an agent that increases the level of epoxy-fatty acids. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 17/416192 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/191 (20130101) Original (OR) Class A61K 31/197 (20130101) A61K 31/221 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/18 (20180101) A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301972 | Chan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| INVENTOR(S) | Marina Chan (Seattle, Washington); Taranjit Gujral (Seattle, Washington) |
| ABSTRACT | The present disclosure is based on the discovery that a clinical grade compound of Formula (I) potently blocks TGF-β activity and significantly reverse the activated phenotypes of myofibroblast in vitro. The compound of Formula (I) can be used in the treatment of fibrotic conditions in general, such as non-alcoholic steatohepatitis (NASH), cirrhosis, HBV infection, any liver disease, pulmonary fibrosis, interstitial lung disease, idiopathic pulmonary fibrosis (IPF), renal fibrosis, cardiac fibrosis, or any combination thereof. |
| FILED | Wednesday, May 19, 2021 |
| APPL NO | 17/999240 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/427 (20130101) Original (OR) Class A61K 31/496 (20130101) A61K 31/4418 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301984 | Swaroop et al. |
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| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Anand Swaroop (Gaithersburg, Maryland); Yu Holly Chen (Chevy Chase, Maryland); Manju Swaroop (Gaithersburg, Maryland); Wei Zheng (Potomac, Maryland); Gregory Tawa (Doylestown, Pennsylvania); Anupam Mondal (Rockville, Maryland); Samantha Papal (Garges-les-Gonesse, France); Wenwei Huang (Rockville, Maryland); Zhiji Luo (Rockville, Maryland) |
| ABSTRACT | Method embodiments are disclosed for treating retinal degeneration in a subject in need thereof. In some embodiments, the method comprises administering to the subject a therapeutically effective amount of compound, and/or a pharmaceutically acceptable salt, prodrug, solvate, hydrate, or tautomer thereof, selected from 3-(dibutylamino)-1-(1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl)propan-1-ol hydrochloride or a compound having a structure according to a formula selected from Formula I, II, or III, as described herein. In some non-limiting examples, the subject has retinitis pigmentosa, LCA, Stargardt’s macular dystrophy, cone-rod dystrophy, choroideremia or age-related macular degeneration. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 18/014045 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/473 (20130101) A61K 31/475 (20130101) Original (OR) Class A61K 31/498 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301998 | RONAI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
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| INVENTOR(S) | Ze'ev A. RONAI (Fallbrook, California); Hyungsoo KIM (San Diego, California) |
| ABSTRACT | Provided herein are methods and compositions for diagnosing, treating, or ameliorating symptoms of cancer, including melanoma, with inhibitors of PRMTS and immune response regulators in combination with checkpoint inhibitor therapy. |
| FILED | Monday, May 03, 2021 |
| APPL NO | 17/997757 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302018 | Laskin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Debra L. Laskin (Basking Ridge, New Jersey); Jaclynn A. Meshanni (Hawthome, New Jersey); Grace L. Guo (Beidgewater, New Jersey); Andrew J. Gow (Princeton, New Jersey); Jeffrey D. Laskin (Piscataway, New Jersey) |
| ABSTRACT | A method of treating reduced pulmonary function by administering an effective dose of a Farnesoid X Receptor (FXR) agonist, particularly obeticholic acid, is disclosed. Also disclosed is an in vivo animal model of lung injury and altered functioning, useful for identifying compounds active in restoring pulmonary function. |
| FILED | Monday, March 27, 2023 |
| APPL NO | 18/190680 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302034 | Grindrod et al. |
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| FUNDED BY |
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| APPLICANT(S) | Shuttle Pharmaceuticals, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott Grindrod (Rockville, Maryland); Mira Jung (Rockville, Maryland); Olga Timofeeva (Rockville, Maryland); Milton Brown (Rockville, Maryland); Anatoly Dritschilo (Rockville, Maryland) |
| ABSTRACT | Methods and formulations are provided for treating cancer and neoplastic diseases in conjunction with radiation therapy where such methods and formulations include a combination of a radiosensitizing agent that is metabolized by thymidine phosphorylase and a thymidine phosphorylase inhibitor that increases the half-life of the radiosensitizing agent. |
| FILED | Sunday, April 02, 2023 |
| APPL NO | 18/194648 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) A61K 31/7072 (20130101) Original (OR) Class A61K 33/243 (20190101) A61K 2121/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302035 | Ting et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David T. Ting (Dover, Massachusetts); Miguel N. Rivera (Belmont, Massachusetts); Vikram Deshpande (Belmont, Massachusetts); Kshitij Arora (North Quincy, Massachusetts); Benjamin Dylan Greenbaum (New York, New York); Alexander V. Solovyov (New York, New York) |
| ABSTRACT | Methods for predicting response to immunotherapy and selecting immunotherapy for treating cancer, e.g., cancer of epithelial origin, in a subject. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/156434 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302036 | MARASCO et al. |
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| FUNDED BY |
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| APPLICANT(S) | CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (Buenos Aires, Argentina); UNIVERSIDAD DE BUENOS AIRES (Buenos Aires, Argentina); COLD SPRING HARBOR LABORATORY (Cold Spring Harbor, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Luciano E. MARASCO (Buenos Aires, Argentina); Alberto R. KORNBLIHTT (Buenos Aires, Argentina); Adrian KRAINER (New York, New York); Jose STIGLIANO (Buenos Aires, Argentina) |
| ABSTRACT | The present disclosure relates compositions and methods to treat neuromuscular diseases and disorders, e.g., spinal muscular atrophy (SMA), characterized by the presence of a splicing silencer located in SMN2 intron 7 pre-mRNA, comprising coadministering a therapeutically effective amount of an antisense oligonucleotide (ASO) complementary to a nucleotide sequence within intron 7 of human SMN2 pre-mRNA; and a subclinical dose of a histone deacetylate inhibitor, e.g., valproic acid, trichostatin A, or a combination thereof. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 18/005514 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/711 (20130101) A61K 31/7125 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2320/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302037 | Bender et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Bender (Orange, Connecticut); Vinod Ramgolam (New Haven, Connecticut); Timur Yarovinsky (Woodbridge, Connecticut) |
| ABSTRACT | In various aspects and embodiments the invention provides compositions and methods useful in the treatment of inflammatory disease, in particular, multiple sclerosis. |
| FILED | Tuesday, June 06, 2023 |
| APPL NO | 18/330357 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7125 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302084 | Demuth et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donald R. Demuth (Louisville, Kentucky); Jill M. Steinbach-Rankins (Louisville, Kentucky) |
| ABSTRACT | Compositions and methods of treating periodontitis are provided. Such compositions and methods typically include a BAR polypeptide and a delivery vehicle. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 18/020235 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0056 (20130101) A61K 9/1647 (20130101) A61K 38/164 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302106 | Cantor et al. |
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| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Harvey Cantor (Boston, Massachusetts); Hye-Jung Kim (Brookline, Massachusetts); Jianmei Wu Leavenworth (Hoover, Alabama) |
| ABSTRACT | Nanoparticles to treat autoimmune diseases and HIV infection are provided. The nanoparticles comprise a biocompatible polymer and a complex, wherein the complex is a major histocompatibility complex (MHC) class I antigen E (HLA-E) linked to a peptide, and wherein the HLA-E-peptide complex is linked to the surface of the nanoparticle. The present invention also relates to methods for treating autoimmune diseases and HIV infection. |
| FILED | Monday, February 27, 2023 |
| APPL NO | 18/114836 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0008 (20130101) Original (OR) Class A61K 2039/58 (20130101) A61K 2039/5154 (20130101) A61K 2039/5158 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/47 (20130101) C07K 14/70539 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2501/2315 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302128 | IRVINE et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Darrell J. IRVINE (Arlington, Massachusetts); Karl Dane Wittrup (Boston, Massachusetts); Tyson Moyer (Boston, Massachusetts); Yash Agarwal (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides immunomodulatory fusion proteins-metal hydroxide complexes comprising an immunomodulatory domain adsorbed to a metal hydroxide via ligand exchange. The disclosure also features compositions and methods of using the same, for example, to treat cancer. |
| FILED | Wednesday, February 22, 2023 |
| APPL NO | 18/172905 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/08 (20130101) A61K 38/20 (20130101) A61K 38/191 (20130101) A61K 38/195 (20130101) A61K 39/3955 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/54 (20130101) C07K 14/521 (20130101) C07K 14/525 (20130101) C07K 16/2809 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302134 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sidi Chen (Milford, Connecticut); Xiaoyun Dai (West Haven, Connecticut); Yaying Du (New Haven, Connecticut); Jonathan Park (Scott AFB, Illinois) |
| ABSTRACT | Compositions and methods for cellular genome engineering that permit simple and efficient targeted knock-in of a CAR and simultaneous knockout of individual genes are described. The compositions and methods are especially applicable to massively parallel engineering, selection, and identification of CAR T cell variants exhibiting a desired phenotype. AAV vectors containing crRNA and CAR expression cassettes and homology arms for targeted genomic integration thereof are provided. Also provided are libraries containing a plurality of AAV vectors and methods of use thereof in screens for identifying desirable CAR T cell variants. Methods of treatment using CAR T cell variants exhibiting improvements in one or more phenotypes are also provided. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 18/041504 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) A61K 39/4631 (20230501) Original (OR) Class A61K 39/4643 (20230501) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 15/907 (20130101) C12N 15/1079 (20130101) C12N 15/1082 (20130101) C12N 2310/20 (20170501) C12N 2750/14143 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302135 | WON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Young-Wook WON (Tucson, Arizona); Byeong-Hyun CHA (Tucson, Arizona); David A. BULL (Tucson, Arizona) |
| ABSTRACT | Described herein are mesenchymal stem cells (MCS) expressing hybrid allosteric receptors (HAR) that are responsive to stromal cell-derived factor 1 alpha (SDF-1α) secreted from acutely infarcted myocardium. Binding of SDF-1α to CXCR4 activates the co-stimulatory signals, bone morphogenetic protein 2 type II receptor (BMP2R2) and BMP type I receptor (ALK3), in order to accelerate the differentiation into cardiomyocytes. HAR-MSC CXCR4 differentiates into cardiomyocytes through Smad1/5 phosphorylation induced by the BMP2 signaling. In acute myocardial infarction (AMI) models, HAR-MSC CXCR4 treatment leads to the functional improvements by facilitated differentiation and increased cytokine secretion. HAR-MSC CXCR4 cells can be used for the treatment of AMI. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 18/042263 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4637 (20230501) Original (OR) Class Peptides C07K 14/71 (20130101) C07K 14/7158 (20130101) C07K 14/70517 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 2501/06 (20130101) C12N 2501/21 (20130101) C12N 2506/1353 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302139 | Disney |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida ResearchFoundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida ResearchFoundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Matthew D. Disney (Jupiter, Florida) |
| ABSTRACT | The protein targeted medicine, Dovitinib, has been repurposed to target a non-coding RNA by using selection and computational drug design via Inforna. Selectivity was achieved for pre-miR-21 by endowing the medicine with the ability to recruit RNA quality control enzymes to cleave the target. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 18/018856 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/545 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302157 | Rodino-Klapac et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Louise Rodino-Klapac (Columbus, Ohio); Jerry R. Mendell (Columbus, Ohio) |
| ABSTRACT | The invention provides gene therapy vectors, such as adeno-associated virus (AAV) vectors, expressing a miniaturized human micro-dystrophin gene and method of using these vectors to express micro-dystrophin in skeletal muscle including diaphragm and cardiac muscle and to protect muscle fibers from injury, increase muscle strength and reduce and/or prevent fibrosis in subjects suffering from muscular dystrophy. |
| FILED | Tuesday, December 27, 2022 |
| APPL NO | 18/146840 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302158 | Daigle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Allen Institute (Seattle, Washington) |
| ASSIGNEE(S) | Allen Institute (Seattle, Washington) |
| INVENTOR(S) | Tanya Daigle (Lake Forest Park, Washington); Edward Sebastian Lein (Mercer Island, Washington); Boaz P. Levi (Seattle, Washington); John K. Mich (Seattle, Washington); Bosiljka Tasic (Seattle, Washington); Jonathan Ting (Lake Forest Park, Washington); Hongkui Zeng (Seattle, Washington) |
| ABSTRACT | Artificial expression constructs for modulating gene expression in striatal neurons are described. The artificial expression constructs can be used to express heterologous genes in striatal neurons including in striatal medium spiny neuron-pan, striatal medium spiny neuron-indirect pathway, striatal medium spiny neuron-direct pathway, striatal interneuron-cholinergic, and Drd3+ medium spiny neurons in olfactory tubercle. The artificial expression constructs can be used for many purposes, including to research and treat movement disorders such as Parkinson's disease and Huntington's disease. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 18/040961 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) A61K 48/0075 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2750/14144 (20130101) Enzymes C12Y 401/01028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302191 | Niu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Hong Niu (St. Louis, Missouri); Ya Guan (St. Louis, Missouri); Jianjun Guan (St. Louis, Missouri) |
| ABSTRACT | In one aspect, a composition for sustained release of oxygen to a tissue is disclosed that includes at least one core-shell oxygen release microsphere (ORM), wherein the core includes a water-soluble polymer-reactive oxygen species (ROS) complex and the shell includes a biodegradable polymer conjugated to a ROS-scavenging enzyme. In some aspects, the reactive oxygen species includes hydrogen peroxide (H2O2), the ROS-scavenging enzyme includes catalase, the water-soluble polymer includes polyvinylpyrrolidone (PVP), and the biodegradable polymer includes poly(N-isopropylacrylamide-co-2-hydroxyethyl methacrylate-co-acrylate-oligolactide-co-Nacryloxysuccinimide)[poly(NIPAAm-co-HEMA-co-AOLA-co-NAS)]. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/162387 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/0004 (20130101) Original (OR) Class A61L 26/008 (20130101) A61L 26/0014 (20130101) A61L 26/0047 (20130101) A61L 2300/10 (20130101) A61L 2300/254 (20130101) Compositions of Macromolecular Compounds C08L 33/26 (20130101) C08L 39/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302196 | XIE et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jingwei XIE (Omaha, Nebraska); Shixuan CHEN (Elkhorn, Nebraska) |
| ABSTRACT | Nanofiber structures are provided as well as methods of use thereof and methods of making. |
| FILED | Tuesday, July 20, 2021 |
| APPL NO | 18/015094 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) Original (OR) Class A61L 27/34 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 2300/418 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) A61L 2430/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302236 | LONGEST et al. |
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| FUNDED BY |
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| APPLICANT(S) | VIRGINA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip Worth LONGEST (Midlothian, Virginia); Michael HINDLE (North Chesterfield, Virginia); Dale FARKAS (Mechanicsville, Virginia); Susan BOC (Burlingame, California) |
| ABSTRACT | Containment units, dry powder inhalers, delivery systems, and methods for the same are disclosed. Exemplary devices are configured to have inlets and outlets which are formed with the containment walls of a containment unit. Air jets formed by the configuration of inlet(s) and outlet(s) inside the containment unit create significant turbulence and deaggregate the powder. Delivery system components downstream of the containment unit may integrate the exiting aerosol plume with a low flow nasal cannula air stream for delivery to a subject. |
| FILED | Monday, May 15, 2023 |
| APPL NO | 18/317245 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 15/0008 (20140204) A61M 15/0021 (20140204) A61M 15/0028 (20130101) Original (OR) Class A61M 15/0086 (20130101) A61M 15/0091 (20130101) A61M 2202/064 (20130101) A61M 2206/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303493 | Conrad et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); SAN JOSE STATE UNIVERSITY RESEARCH FOUNDATION (San Jose, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laura Miller Conrad (Redwood City, California); Martin F. Semmelhack (Princeton, New Jersey); Zinan Zhang (Decatur, Georgia); Minh Tran (San Francisco, California); Lauren Blankenship (College Station, Texas) |
| ABSTRACT | In one aspect, compounds and methods are described herein for treating gram negative bacteria having resistance to cationic antimicrobial peptides. In some embodiments, for example, compounds of formula I are provided. In another aspect, a treatment for a gram negative bacterial infection comprises a cationic antimicrobial protein (CAP) in conjunction with a compound of formula I. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 18/021284 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/12 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 213/75 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303496 | Narayanan et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramesh Narayanan (Cordova, Tennessee); Thamarai Ponnusamy (Memphis, Tennessee); Duane D. Miller (Collierville, Tennessee); Yali He (Germantown, Tennessee); Dong-Jin Hwang (Arlington, Tennessee) |
| ABSTRACT | This invention relates to selective androgen receptor covalent antagonists, synthetic intermediates and by-products, and related compounds, and compositions comprising the same, and uses thereof in treating androgen receptor dependent diseases and conditions such as hyperproliferations of the prostate including pre-malignancies and benign prostatic hyperplasia, prostate cancer, advanced prostate cancer, castration resistant prostate cancer, triple negative breast cancer, other cancers expressing the androgen receptor, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/821952 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 231/12 (20130101) C07D 231/14 (20130101) Original (OR) Class C07D 403/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303499 | LAWRENCE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas J. LAWRENCE (Lutz, Florida); Harshani Rithma LAWRENCE (Lutz, Florida); Derek DUCKETT (Land O Lakes, Florida); Gary REUTHER (Temple Terrace, Florida) |
| ABSTRACT | The present disclosure provides anti-cancer compounds and uses thereof, more particularly inhibitors of ACK1 tyrosine kinase and their use in the treatment of cancer. |
| FILED | Monday, August 16, 2021 |
| APPL NO | 18/021318 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 239/48 (20130101) Original (OR) Class C07D 403/12 (20130101) C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303501 | Marugan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); Pontificia Universidad Católica de Chile (Santiago, Chile) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); Pontificia Universidad Católica de Chile (Santiago, Chile) |
| INVENTOR(S) | Juan J. Marugan (Gaithersburg, Maryland); Marc Ferrer (Potomac, Maryland); Noel T. Southall (Potomac, Maryland); Andres E. Dulcey (Gaithersburg, Maryland); Xin Hu (Frederick, Maryland); Christopher R. Dextras (Frederick, Maryland); Daniel C. Talley (Baltimore, Maryland); Alejandra Alvarez (Santiago, Chile); Silvana Zanlungo (Santiago, Chile); Rommy M. Von Bernhardi (Santiago, Chile) |
| ABSTRACT | Disclosed herein are embodiments of a compound that inhibits c-Abl tyrosine kinase (also referred to herein as “c-Abl”). The compound embodiments described herein are novel c-Abl inhibitors that can bind to c-Abl at an allosteric site and inhibit its activity in various pathways. The compound embodiments also are capable of crossing the blood brain barrier and therefore are useful in inhibiting c-Abl activity as it affects pathways and/or proteins in the brain. The compound embodiments described herein are effective therapeutic agents for treating diseases involving c-Abl, such as cancers, motor neuron diseases, and neurodegenerative diseases. Also disclosed herein are embodiments of methods for making and using the c-Abl inhibitory compound embodiments. |
| FILED | Thursday, March 30, 2023 |
| APPL NO | 18/128603 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/553 (20130101) A61K 31/554 (20130101) A61K 31/5513 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) A61P 25/28 (20180101) A61P 33/06 (20180101) A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 201/12 (20130101) C07C 227/22 (20130101) C07C 319/14 (20130101) Heterocyclic Compounds C07D 243/38 (20130101) Original (OR) Class C07D 267/18 (20130101) C07D 267/20 (20130101) C07D 281/16 (20130101) C07D 401/04 (20130101) C07D 403/04 (20130101) C07D 413/04 (20130101) C07D 413/10 (20130101) C07D 413/14 (20130101) C07D 417/04 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) C07F 7/0812 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303531 | Speerschneider et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trevena, Inc. (Chesterbrook, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aimee Crombie Speerschneider (Chesterbrook, Pennsylvania); Dennis Shinji Yamashita (Chesterbrook, Pennsylvania); Philip Michael Pitis (Chesterbrook, Pennsylvania); Michael John Hawkins (Chesterbrook, Pennsylvania); Guodong Liu (Chesterbrook, Pennsylvania); Tamara Ann Miskowski Daubert (Chesterbrook, Pennsylvania); Catherine C.K. Yuan (Chesterbrook, Pennsylvania); Robert Borbo Kargbo (Chesterbrook, Pennsylvania); Robert Jason Herr (Chesterbrook, Pennsylvania); Donna Romero (Chesterbrook, Pennsylvania) |
| ABSTRACT | The present embodiments are directed, in part, to compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof for modulating the activity of delta opioid receptor, biased and/or unbiased, and/or methods for treating pain, migraines, headaches, depression, Parkinsons Disease, anxiety, and/or overactive bladder, and other disorders and conditions described herein or any combination thereof. |
| FILED | Wednesday, May 10, 2023 |
| APPL NO | 18/314913 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/06 (20180101) A61P 25/22 (20180101) A61P 25/24 (20180101) A61P 29/00 (20180101) Heterocyclic Compounds C07D 403/12 (20130101) Original (OR) Class C07D 403/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303563 | HOYT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN (Bethesda, Maryland); KUROME THERAPEUTICS, INC. (Cincinnati, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott Bryan HOYT (Arlington, Virginia); Craig Joseph THOMAS (Gaithersburg, Maryland); Chris James FINOCCHIO (Virginia Beach, Virginia); Daniel T. STARCZYNOWSKI (Cincinnati, Ohio); Gregory J. TAWA (Doylestown, Pennsylvania); Gabriel GRACIA MALDONADO (Cincinnati, Ohio); Jan Susan ROSEBAUM (Cincinnati, Ohio) |
| ABSTRACT | Some embodiments of the disclosure include disclosed compounds (e.g., compounds of Formula (I)) and compositions (e.g., pharmaceutical compositions) which inhibit IRAK and/or FLT3 and which can be used for treating, for example, certain diseases. Some embodiments include methods of using the disclosed compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as hematopoietic cancers, myelodysplastic syndromes (MDS), acute myeloid leukemia (AML), etc.). Additional embodiments provide disease treatment using combinations of the disclosed IRAK and/or FLT3 inhibiting compounds with other therapies, such as cancer therapies. |
| FILED | Saturday, July 31, 2021 |
| APPL NO | 18/018742 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303569 | Sokolova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arisan Therapeutics Inc. (Carlsbad, California) |
| ASSIGNEE(S) | Arisan Therapeutics Inc. (Carlsbad, California) |
| INVENTOR(S) | Nadezda Sokolova (San Diego, California); Kenneth McCormack (Oceanside, California); Gregory Henkel (Carlsbad, California); Vidyasagar Reddy Gantla (San Diego, California); Eric Brown (Santee, California) |
| ABSTRACT | The invention relates to compounds of structural formula 1 wherein A is independently N or C—R3, R1 is selected from (C1 to C6) alkyl, (C2 to C6) alkenyl, (C2 to C6) alkynyl, (C3 to C10) cycloalkyl, (C5 to C10) cycloalkenyl, (C2 to C6) heterocycloalkyl, (C6 to C10) aryl, and (C2 to C9) heteroaryl, wherein each of the said (C1 to C6) alkyl, (C2 to C6) alkenyl, (C2 to C6) alkynyl, (C3 to C10) cycloalkyl, (C5 to C10) cycloalkenyl, (C2 to C9) heterocycloalkyl, (C6 to C10) aryl, and (C2 to C9) heteroaryl is optionally substituted with at least one R4 group, and wherein said (C2 to C9) heteroaryl is C-attached, and R2 is selected from the group consisting of |
| FILED | Thursday, May 11, 2023 |
| APPL NO | 18/316004 |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303581 | Ibrahim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Mississippi (University, Mississippi) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohamed Ali Mohamed Ali Ibrahim (Oxford, Mississippi); Jason Richard Paris (Little Rock, Arkansas); Larry Anthony Walker (Milan, Tennessee); Abbas Gholipour Shilabin (Johnson City, Tennessee); Meirambek Ospanov (Oxford, Mississippi) |
| ABSTRACT | The disclosure relates to compounds of Formula I, methods of making same, pharmaceutical compositions including same, and methods of treating pain and neurological disorders using same: wherein R1 is hydrogen, halogen, hydroxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, aryl, nitro, or cyano; wherein R2 and R3 are independently hydrogen, halogen, aryl, or substituted or unsubstituted alkyl, or wherein R2 and R3 are connected to form an alkyl chain; wherein R4 is a substituted or unsubstituted aryl or heteroaryl group having from 5 to 10 members; wherein X is O, S, N, NH, CH, CH2, or CO; wherein n is from 0 to 10; and wherein the bond indicated by * is a double bond or a single bond based on a valence of X. The compounds selectively bind to CB2, can penetrate the blood brain barrier, and have a half-life of 20 hours or greater. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/191247 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/04 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303584 | Ouyang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SUVALENT THERAPEUTICS INC. (Thousand Oaks, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaohu Ouyang (Rosemead, California); Miles Douglas Kubota (Monravia, California); Andrew Stewart Tasker (Simi Valley, California); Fang-Tsao Hong (Thousand Oaks, California); Mary Walton (Camarillo, California); Victor J. Cee (Thousand Oaks, California) |
| ABSTRACT | The present invention relates to compounds and compositions capable of acting as inhibitors of small ubiquitin-like modifier (SUMO) family of proteins. The compounds and compositions may be used in the treatment of cancer. There are disclosed, inter alia, methods of inhibiting an E1 enzyme, and compounds useful for inhibiting an E1 enzyme. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/793191 |
| CURRENT CPC | Heterocyclic Compounds C07D 495/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303598 | DONG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yizhou DONG (Dublin, Ohio); Yuebao ZHANG (Columbus, Ohio) |
| ABSTRACT | The present disclosure relates to compounds, compositions, and methods for delivery of therapeutic, diagnostic, or prophylactic agents (for example, a nucleic acid). |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 18/022017 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 9/5146 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/10 (20130101) C07F 9/2458 (20130101) Original (OR) Class C07F 9/4075 (20130101) C07F 9/65515 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303630 | Gradinaru et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Capsida, Inc. (Thousand Oaks, California); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Viviana Gradinaru (Pasadena, California); Nicholas C. Flytzanis (Thousand Oaks, California); Nicholas S. Goeden (Thousand Oaks, California); Karl Beutner (La Canada Flintridge, California) |
| ABSTRACT | Described herein are compositions and kits comprising recombinant adeno-associated viruses (rAAVs) with tropisms showing increased viral transduction in the CNS. The rAAV compositions described herein encapsidate a transgene, such as a therapeutic nucleic acid. Gene therapy using the rAAVs is described. Also described are methods of treating CNS-related diseases and conditions. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 18/022056 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303634 | Xia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongjie Xia (Galveston, Texas); Xuping Xie (Galveston, Texas); Pei-Yong Shi (Galveston, Texas) |
| ABSTRACT | Certain embodiments of the invention include recombinant reverse genetic systems for Omicron variant of SARS-CoV-2 virus. |
| FILED | Tuesday, December 06, 2022 |
| APPL NO | 18/076315 |
| CURRENT CPC | Peptides C07K 14/165 (20130101) Original (OR) Class C07K 2319/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303653 | PAYNE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aimee S. PAYNE (Merion Station, Pennsylvania); Christoph T. ELLEBRECHT (Philadelphia, Pennsylvania); Vijay BHOJ (Philadelphia, Pennsylvania); Michael C. MILONE (Cherry Hill, New Jersey) |
| ABSTRACT | The invention includes compositions comprising at least one chimeric autoantibody receptor (CAAR) specific for an autoantibody, vectors comprising the same, compositions comprising CAAR vectors packaged in viral particles, and recombinant T cells comprising the CAAR. The invention also includes methods of making a genetically modified T cell expressing a CAAR (CAART) wherein the expressed CAAR comprises a desmoglein extracellular domain. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/156442 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) A61K 48/00 (20130101) A61K 2039/57 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303661 | CONNOLLY et al. |
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| FUNDED BY |
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| APPLICANT(S) | Parker Institute for Cancer Immunotherapy (San Francisco, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John CONNOLLY (Red Oak, Texas); Sean PARKER (San Francisco, California); Kenan Christopher GARCIA (San Francisco, California) |
| ABSTRACT | The present disclosure generally relates to, inter alia, a class of chimeric switch receptors containing an endodomain of an IL-9 receptor, engineered to modulate transcriptional regulation in a ligand-dependent manner. The disclosure also provides compositions and methods useful for producing such receptors, nucleic acids encoding same, host cells genetically modified with the nucleic acids, as well as methods for modulating gene expression, modulating an activity of a cell, and/or for the treatment of various health conditions or diseases. |
| FILED | Friday, June 02, 2023 |
| APPL NO | 18/328473 |
| CURRENT CPC | Peptides C07K 14/7155 (20130101) Original (OR) Class C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303666 | Regev et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Xun Chen (Cambridge, Massachusetts) |
| ABSTRACT | The present invention discloses antibodies capable of binding to and neutralizing SARS-CoV-2 and variants thereof. The invention also discloses a cell-free antibody engineering platform capable of identifying antibodies that bind to specific target molecules and virus-neutralizing antibodies. |
| FILED | Friday, September 24, 2021 |
| APPL NO | 18/026866 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/22 (20130101) C07K 2317/24 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303667 | Ahmed et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rafi Ahmed (Atlanta, Georgia); Carl Davis (Atlanta, Georgia); Erica Ollmann Saphire (Solana Beach, California) |
| ABSTRACT | This disclosure relates to antibodies and antigen binding fragments that specifically bind Ebola virus particles. In certain embodiments, the antibodies and fragments are capable of treating or preventing an Ebola viral infection. In certain embodiments, the antibodies and antigen binding fragments are also contemplated for diagnostic methods and compositions related thereto. |
| FILED | Friday, June 09, 2023 |
| APPL NO | 18/332291 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/71 (20130101) C07K 2317/72 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/524 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303776 | GIANNESCHI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Nathan C. GIANNESCHI (Wilmette, Illinois); Yifei LIANG (Evanston, Illinois); Hao SUN (Evanston, Illinois) |
| ABSTRACT | Aspects disclosed herein include fully or partially degradable polymers, liquid formulations comprising such polymers, methods for treating or managing a condition in a subject using such polymers, methods for using such polymers, and methods of synthesizing such polymers. Aspects disclosed herein also include monomers suitable for forming a partially or fully degradable polymer and methods for forming such monomers. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 18/012001 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/04 (20130101) Original (OR) Class C08G 2261/334 (20130101) C08G 2261/418 (20130101) Compositions of Macromolecular Compounds C08L 85/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303967 | Wilson |
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| FUNDED BY |
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| APPLICANT(S) | Wilson Wolf Manufacturing (New Brighton, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John R. Wilson (New Brighton, Minnesota) |
| ABSTRACT | This invention relates to methods and devices that improve cell culture efficiency. They include the use of gas permeable culture compartments that reduce the use of space while maintaining uniform culture conditions, and are more suitable for automated liquid handling. They include the integration of gas permeable materials into the traditional multiple shelf format to resolve the problem of non-uniform culture conditions. They include culture devices that use surfaces comprised of gas permeable, plasma charged silicone and can integrate traditional attachment surfaces, such as those comprised of traditional tissue culture treated polystyrene. They include culture devices that integrate gas permeable, liquid permeable membranes. A variety of benefits accrue, including more optimal culture conditions during scale up and more efficient use of inventory space, incubator space, and disposal space. Furthermore, labor and contamination risk are reduced. |
| FILED | Friday, May 26, 2023 |
| APPL NO | 18/202781 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/08 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303976 | Gros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Alena Gros (Barcelona, Spain); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed are methods of isolating T cells and TCRs having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Also disclosed are related methods of preparing a population of cells, populations of cells, TCRs, pharmaceutical compositions, and methods of treating or preventing cancer. |
| FILED | Monday, February 27, 2023 |
| APPL NO | 18/174928 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1703 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303983 | Florea et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Florea (Cambridge, Massachusetts); Amy J. Wagers (Cambridge, Massachusetts); Luk Vandenberghe (Weston, Massachusetts) |
| ABSTRACT | Disclosed herein are optimized methods of high efficiency purification of adeno-associated virus (AAV) particles, comprising a step of binding one or more AAV particles with a volume of chromatography resin medium comprising at least one ligand possessing a pan-AAV affinity. The optimized methods are capable of providing purified AAV particles comprising a wide diversity of AAV serotypes without the need to further optimize for a given AAV serotype. |
| FILED | Thursday, May 12, 2022 |
| APPL NO | 17/743444 |
| CURRENT CPC | Separation B01D 15/361 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/02 (20130101) Original (OR) Class C12N 15/8645 (20130101) C12N 2750/14143 (20130101) C12N 2750/14151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303985 | IAVARONE et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Antonio IAVARONE (New York, New York); Anna LASORELLA (New York, New York); Raul RABADAN (New York, New York) |
| ABSTRACT | The invention discloses oncogenic fusion proteins. The invention provides methods for treating gene-fusion based cancers. |
| FILED | Wednesday, October 12, 2022 |
| APPL NO | 18/046131 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/53 (20130101) A61K 31/404 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/4439 (20130101) A61K 38/179 (20130101) Peptides C07K 14/47 (20130101) C07K 14/71 (20130101) C07K 14/435 (20130101) C07K 14/4738 (20130101) C07K 16/40 (20130101) C07K 2317/76 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Original (OR) Class C12N 9/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Enzymes C12Y 207/10001 (20130101) C12Y 301/03003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/57484 (20130101) G01N 2333/71 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304000 | Josephs et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Josephs (Durham, North Carolina); Dewran Kocak (Durham, North Carolina); Piotr Marszalek (Durham, North Carolina); Charles A. Gersbach (Chapel Hill, North Carolina) |
| ABSTRACT | Disclosed herein are optimized guide RNAs (gRNAs) and methods of designing and using said optimized gRNAs that have increased target binding specificity and reduced off-target binding. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 17/897033 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/10 (20190201) G16B 15/30 (20190201) G16B 25/00 (20190201) G16B 30/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304001 | Vora et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Suhani D. Vora (Cambridge, Massachusetts); Alejandro Chavez (New York, New York); Jing Cheng (Mountain View, California); Benjamin W. Pruitt (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides methods and compositions of modulating expression of a target nucleic acid sequence in a cell. The method comprises introducing into the cell a nucleic acid sequence encoding a Cas9 fusion protein and a guide RNA, wherein the Cas9 fusion protein and the guide RNA are expressed and co-localize at a target site and modulate the expression of the target nucleic acid sequence. |
| FILED | Tuesday, April 25, 2023 |
| APPL NO | 18/306298 |
| CURRENT CPC | Peptides C07K 14/31 (20130101) C07K 14/315 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/86 (20130101) C12N 15/111 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304006 | Bahal et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut); Beth Deacon Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raman Bahal (Glastonbury, Connecticut); Shipra Malik (Storrs, Connecticut); Frank Slack (Waban, Massachusetts) |
| ABSTRACT | Described herein is a modified anti-seed PNA including 5′-Xaa1Xaa2Xaa3-N1N2N3N4N5N6N7N8 N9-Xaa4-3′, wherein Xaa1, Xaa2, Xaa3, and Xaa4 are each independently R or K, wherein N1N2N3N4N5N6N7N8 N9 is a PNA which Watson-Crick base pairs to a seed sequence of an miRNA, wherein N8 and N9 may be null. Also included are methods of inhibiting expression of a miRNA in vivo or in vitro, and methods of treating cancer and other diseases and disorders with the modified anti-see PNAs. |
| FILED | Tuesday, August 17, 2021 |
| APPL NO | 18/041271 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/351 (20130101) C12N 2310/3181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304012 | FALLON et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Justin R. FALLON (Providence, Rhode Island); Laura A. MADIGAN (Pawtucket, Rhode Island); Ashley E. WEBB (Providence, Rhode Island); Beth MCKECHNIE (Attleboro, Massachusetts); Lauren FISH (East Greenwich, Rhode Island); Diego JAIME (Providence, Rhode Island); John PAGE (Storrs, Connecticut) |
| ABSTRACT | Methods and compositions for increasing muscle regeneration and for preventing or treating diseases, disorders or conditions associated with neuromuscular dysfunction, are provided herein. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/769165 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 38/465 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/321 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304022 | Barbas, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carlos F. Barbas, III (La Jolla, California); Andrew Mercer (Poolesville, Maryland); Brian M. Lamb (San Diego, California); Thomas Gaj (Solana Beach, California) |
| ABSTRACT | Disclosed herein are chimeric polypeptides, including compositions thereof, expression vectors, and methods of use thereof, for the generation of transgenic cells, tissues, plants, and animals. The compositions, vectors, and methods of the present invention are also useful in gene therapy techniques. |
| FILED | Friday, September 23, 2022 |
| APPL NO | 17/951849 |
| CURRENT CPC | Peptides C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) C12N 15/62 (20130101) Original (OR) Class C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304024 | Crabtree et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gerald R. Crabtree (Stanford, California); Sai Gourisankar (Stanford, California); Andrey Krokhotin (Stanford, California); Chiung-Ying Chang (Stanford, California); Wendy Christine Wenderski (Stanford, California); Samuel Heeju Kim (Stanford, California); Nathanael Gray (Stanford, California); Xiaofan Liu (Stanford, California); Zhengnian Li (Stanford, California); Tinghu Zhang (Stanford, California) |
| ABSTRACT | Methods of modulating transcription of a target gene in a cell (which may be in vitro or in vivo) are provided. Aspects of the methods employ a transcription factor-chemical inducer of proximity (TF-CIP) system to modulate, e.g., enhance or reduce, transcription of a target gene in a cell. Embodiments of the methods include providing in a cell a chemical inducer of proximity (CIP) which links a first endogenous anchor transcription factor that binds to a promoter of the target gene and a second endogenous transcription modulating factor (e.g., a transcription factor or transcription repressor), wherein CIP mediated linkage of the anchor transcription factor and transcription modulating factor modulates transcription of the target gene in the cell. Also provided are compositions that find use in practicing methods of the invention. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/143492 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/55 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304033 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chengwen Li (Chapel Hill, North Carolina); Richard Jude Samulski (Hillsborough, North Carolina) |
| ABSTRACT | The present invention is in the field of recombinant adeno-associated virus (AAV) vectors. In particular, the invention relates to AAV vectors comprising modified AAV capsid proteins that evade neutralizing antibodies but are still able to transduce hepatocytes. The invention further relates to methods of using the AAV vectors to deliver products to subjects and treat diseases. |
| FILED | Monday, May 03, 2021 |
| APPL NO | 17/997791 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0041 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304039 | Pekrun et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Katja Pekrun (Palo Alto, California); Mark A. Kay (Los Altos, California) |
| ABSTRACT | The present invention relates to variant AAV capsid polypeptides, wherein the variant AAV capsid polypeptides exhibit increased transduction and/or tropism in human pancreatic tissue or human islets as compared non-variant parent capsid polypeptides. |
| FILED | Tuesday, December 06, 2022 |
| APPL NO | 18/062333 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6901 (20170801) Peptides C07K 14/015 (20130101) C07K 14/075 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304042 | Ertl et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE WISTAR INSTITUTE (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hildegund C.J. Ertl (Villanova, Pennsylvania); Xiang Yang Zhou (North Wales, Pennsylvania) |
| ABSTRACT | This disclosure provides replication-incompetent adenoviral vectors useful in vaccine development and gene therapy. The disclosed vectors comprise a selective deletion of E3 and are particularly useful for preparation of vaccines development and for gene therapy using toxic transgene products that result in vector instability that occurs when the entire E3 domain is deleted. |
| FILED | Wednesday, May 31, 2023 |
| APPL NO | 18/203818 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 39/29 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/861 (20130101) C12N 2710/10343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304063 | Gottesman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTESS OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTESS OF THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Maxwell Gottesman (New York, New York) |
| ABSTRACT | The present disclosure provides host cells for reliable, high yield recombinant protein production, including unstable proteins. The present host cell (e.g., a bacterial cell) is deficient in at least one protease (or a subunit of a protease) such as Clp or ClpP. The host cell may also contain an expression vector that encodes a protein or polypeptide for overexpression. |
| FILED | Friday, February 03, 2023 |
| APPL NO | 18/105587 |
| CURRENT CPC | Peptides C07K 14/245 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) C12N 15/70 (20130101) C12N 15/102 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304064 | KIRBY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James E. KIRBY (Weston, Massachusetts); Kenneth P. Smith (Jamaica Plain, Massachusetts) |
| ABSTRACT | Provided herein are systems, methods, and articles of manufacture for automated antimicrobial testing. In particular, the systems and methods provided herein are directed to automated antimicrobial susceptibility testing platforms and methods for identification of synergistic antimicrobials that are faster, more precise, and less expensive than gold standard susceptibility methodologies. |
| FILED | Thursday, June 01, 2017 |
| APPL NO | 16/309368 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/1016 (20130101) G01N 2035/1039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304073 | SEELIG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Georg SEELIG (Seattle, Washington); Alexander B. ROSENBERG (Seattle, Washington); Charles ROCO (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a nucleus, a plurality of nuclei, a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a nucleus, a plurality of nuclei, a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs and/or cDNAs. |
| FILED | Friday, April 21, 2023 |
| APPL NO | 18/304670 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 2521/107 (20130101) C12Q 2525/161 (20130101) C12Q 2543/101 (20130101) C12Q 2563/179 (20130101) C12Q 2563/185 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230304074 — METHODS AND SYSTEMS FOR DETERMINING SPATIAL PATTERNS OF BIOLOGICAL TARGETS IN A SAMPLE
| US 20230304074 | Chee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| ASSIGNEE(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Mark S. Chee (San Diego, California); David A. Routenberg (San Diego, California) |
| ABSTRACT | The present disclosure provides methods and assay systems for use in spatially encoded biological assays, including assays to determine a spatial pattern of abundance, expression, and/or activity of one or more biological targets across multiple sites in a sample. In particular, the biological targets comprise proteins, and the methods and assay systems do not depend on imaging techniques for the spatial information of the targets. The present disclosure provides methods and assay systems capable of high levels of multiplexing where reagents are provided to a biological sample in order to address tag the sites to which reagents are delivered; instrumentation capable of controlled delivery of reagents; and a decoding scheme providing a readout that is digital in nature. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/129357 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304088 | Ranum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Laura Ranum (Gainesville, Florida); Amrutha Pattamatta (Gainesville, Florida); Eric Tzy-Shi Wang (Gainesville, Florida); Hailey Olafson (Gainesville, Florida) |
| ABSTRACT | Aspects of the disclosure relate to methods and compositions (e.g., biomarkers) useful for diagnosing pre- symptomatic amyotrophic lateral sclerosis (ALS) and/or frontotemporal dementia (FTD), and for monitoring the progression of ALS/FTD in subjects diagnosed with the disease. Methods of treating neurodegenerative diseases (e.g., ALS/FTD) are also described. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/925054 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304099 | Xiong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donghai Xiong (Milwaukee, Wisconsin); Ming You (Milwaukee, Wisconsin); Yian Wang (Milwaukee, Wisconsin) |
| ABSTRACT | The present invention provides novel gene signature associated with immune checkpoint inhibitor (ICT) named ImmuneCells.Sig which is predicative of ICT outcomes of melanoma patients which is significantly more accurate than all previously reported ICT response signatures. The ImmuneCells.Sig can be used as an accurate predictor of ICT response and may be used to determine if a patient will be susceptible and respond to ICT treatment. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 18/041534 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304997 | TRAVIS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander J. TRAVIS (Ithaca, New York); Gianpiero PALERMO (New York, New York) |
| ABSTRACT | This disclosure provides a method for determining male fertility status. The method comprises determining GM1 distribution patterns following induced sperm capacitation, identifying the frequency of distribution of various patterns, and determining if the frequency distribution of certain GM1 patterns in response to induced capacitation is altered. Based on the change in the frequency distribution patterns of certain patterns in response to induced capacitation, alone or in combination with other sperm attributes, male fertility status can be identified. |
| FILED | Friday, May 26, 2023 |
| APPL NO | 18/324518 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/689 (20130101) G01N 33/5044 (20130101) G01N 33/5091 (20130101) Original (OR) Class G01N 2800/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230305006 | XUAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng XUAN (Cambridge, Massachusetts); Yu Wang (Cambridge, Massachusetts); Peng Yin (Cambridge, Massachusetts); Tsz Wing Fan (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are methods, compositions, kits, and systems for the detection of neutralization targets such as neutralizing antibodies. |
| FILED | Tuesday, April 04, 2023 |
| APPL NO | 18/130523 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) Original (OR) Class G01N 2333/165 (20130101) G01N 2458/10 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230305090 | Darwish et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Siemens Healthcare GmbH (Erlangen, Germany); Centre National de la Recherche Scientifique (CNRS) (Paris, France); Institut National de La Sante et de la Recherche Medicale (INSERM) (Paris, France); King's College London (London, United Kingdom); Department of Health and Human Services (Bethesda, Maryland); UNIV PARIS XIII PARIS-NORD VILLETANEUSE (Villetaneuse, France); Universite de Paris (Paris, France) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Omar Darwish (London, United Kingdom); Radhouene Neji (London, United Kingdom); Ahmed M. Gharib (Bethesda, Maryland); Ralph Sinkus (Parmain, France) |
| ABSTRACT | The present disclosure is directed to techniques for synchronizing a rotational eccentric mass of a gravitational transducer used for a magnetic resonance elastography acquisition with a corresponding magnetic resonance elastography scan carried out by a magnetic resonance imaging system, wherein the rotation of the eccentric mass is driven by a shaft. The method includes starting the rotation of the eccentric mass at a set vibration frequency and the magnetic resonance elastography scan at a set acquisition frequency; determining the rotational position of the shaft; defining the rotational position as first reference position; calculating further reference positions. At the start time of each subsequent acquisition period, determining the current rotational position of the shaft; comparing the determined current rotational position with the theoretically expected reference position and decreasing or increasing the rotational speed of the rotational eccentric mass based on the comparison. |
| FILED | Wednesday, March 23, 2022 |
| APPL NO | 17/702212 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/30 (20130101) G01R 33/56358 (20130101) Original (OR) Class Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 8/08 (20130101) H02P 8/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306303 | Wall et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Dennis Paul Wall (Palo Alto, California); Peter Yigitcan Washington (Stanford, California) |
| ABSTRACT | Systems and methods for crowdsourced machine learning in accordance with embodiments of the invention are illustrated. In many embodiments, particular crowdworkers from a plurality of crowdworkers who are able to perform with high accuracy and reliability (referred to herein as “super recognizers”) are identified and used to generate training data for machine learning models. In various embodiments, super recognizers are identified by providing a request to answer questions regarding a particular type of input to the plurality of crowdworkers and providing received answers to a machine learning model trained using expert-annotated inputs similar to the inputs provided to the crowdworkers. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 18/020907 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306562 | Pang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jiaxuan Pang (Tempe, Arizona); DongAo Ma (Tempe, Arizona); Jiangming Liang (Scottsdale, Arizona) |
| ABSTRACT | Described herein are means for performing self-supervised visual representation learning using order and appearance recovery on a vision transformer. An exemplary system having a processor and memory is specially configured to execute instructions including: receiving medical image training data; selecting a medical image; generating a first perturbed image by applying local pixel shuffling and other image perturbations and outputting a first patchified perturbed image; generating a second randomized patchified image by patchifying and applying a random permutation to the original image; inputting the first patchified perturbed image and the second randomized patchified image into first and second transformer encoders which each generate and then share first and second generated weights through the recovery of both and patch order appearance from each image; and outputting a pre-trained AI model to perform medical image diagnosis on a new medical image absent from the training data input received by the system. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/126317 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/005 (20130101) Original (OR) Class G06T 5/10 (20130101) G06T 7/0012 (20130101) G06T 2207/20021 (20130101) G06T 2207/20032 (20130101) G06T 2207/20048 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20092 (20130101) G06T 2207/20192 (20130101) G06T 2207/30004 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306595 | Leuthardt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Eric Leuthardt (St. Louis, Missouri); Carl Hacker (St. Louis, Missouri); Shan Siddiqi (St. Louis, Missouri); Tim Laumann (St. Louis, Missouri); Andy Daniel (St. Louis, Missouri) |
| ABSTRACT | A method for selecting a seed region for use in a seed-based cortical functional mapping method includes providing at least one RSN map of at least one subject, each of the at least one RSN maps comprising a plurality of functional voxels within a brain of each of the at least one subjects, each functional voxel of the plurality of functional voxels associated with a probability of membership in an RSN. A subset of the functional voxels characterizing a contiguous region is selected as the seed region, each functional voxel of the seed region having a probability of membership in the RSN above a threshold value. |
| FILED | Tuesday, May 23, 2023 |
| APPL NO | 18/322345 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 5/4848 (20130101) A61B 5/7267 (20130101) A61B 34/10 (20160201) A61B 2034/107 (20160201) A61B 2576/026 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Electric Digital Data Processing G06F 18/213 (20230101) G06F 18/2178 (20230101) G06F 18/2415 (20230101) G06F 18/24133 (20230101) Computer Systems Based on Specific Computational Models G06N 3/00 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20084 (20130101) Image or Video Recognition or Understanding G06V 10/764 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306723 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | DongAo Ma (Tempe, Arizona); Jiaxuan Pang (Tempe, Arizona); Nahid Ul Islam (Mesa, Arizona); Mohammad Reza Hosseinzadeh Taher (Tempe, Arizona); Fatemeh Haghighi (Tempe, Arizona); Jianming Liang (Scottsdale, Arizona) |
| ABSTRACT | Described herein are systems, methods, and apparatuses for implementing self-supervised domain-adaptive pre-training via a transformer for use with medical image classification in the context of medical image analysis. An exemplary system includes means for receiving a first set of training data having non-medical photographic images; receiving a second set of training data with medical images; pre-training an AI model on the first set of training data with the non-medical photographic images; performing domain-adaptive pre-training of the AI model via self-supervised learning operations using the second set of training data having the medical images; generating a trained domain-adapted AI model by fine-tuning the AI model against the targeted medical diagnosis task using the second set of training data having the medical images; outputting the trained domain-adapted AI model; and executing the trained domain-adapted AI model to generate a predicted medical diagnosis from an input image not present within the training data. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/126318 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0895 (20230101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10116 (20130101) G06T 2207/20081 (20130101) G06T 2207/20092 (20130101) G06T 2207/30004 (20130101) Image or Video Recognition or Understanding G06V 10/764 (20220101) G06V 10/774 (20220101) Original (OR) Class G06V 10/776 (20220101) G06V 2201/03 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307102 | Yiadom |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Maame Yaa A. B. Yiadom (Palo Alto, California) |
| ABSTRACT | Systems and methods for automated identification of STEMI in accordance with embodiments of the invention are illustrated. One embodiment includes a predictive electronic health record (EHR) system, including a processor, and a memory, the memory containing an EHR management application which configures the processor to obtain preliminary information about a patient via a terminal, store the preliminary information in an EHR, provide the preliminary information to a model trained to predict an emergency medical condition requiring immediate treatment, obtain a likelihood that the patient is suffering from an emergency medical condition from the machine learning model, and provide an alert when the likelihood exceeds a predetermined threshold. In many embodiments, the condition is STEMI, and the preliminary information comprises: age, sex, and at least one chief complaint. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/191222 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) Original (OR) Class G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307130 | ARIAD et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Daniel ARIAD (Pikesville, Maryland); Rajiv MCCOY (Baltimore, Maryland); Manuel VIOTTI (San Francisco, California) |
| ABSTRACT | Provided herein are methods of distinguishing between meiotic- and mitotic-origin aneuploidies in certain embodiments. Related systems and computer program products are also provided. |
| FILED | Friday, November 05, 2021 |
| APPL NO | 18/035811 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/10 (20190201) G16B 20/20 (20190201) G16B 40/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20230301614 | Fang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ruogu Fang (Gainesville, Florida); Peng Liu (Gainesville, Florida) |
| ABSTRACT | Various examples are provided related to reconstructing images such as, e.g., medical images from low-dose image scans. Adversarial learning such as, e.g., a Cyclic Simulation and Denoising (CSD) framework can be used to address challenges of complicated mixed noise in real low-dose scans. The CSD framework can include a simulator model that can extract low-dose noise and features (e.g., tissue features) from separate image spaces into a unified feature space and a denoiser model that can learn how to remove noise and restore features, simultaneously. Both the simulator model and the denoiser model can regularize each other in a cyclic manner to optimize network learning effectively. The CSD framework in combination with phantom scans can embrace the realistic low-dose noise and features into a unified learning environment to address the challenge of real low-dose image restoration. |
| FILED | Thursday, July 29, 2021 |
| APPL NO | 18/007366 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/583 (20130101) A61B 6/5235 (20130101) A61B 6/5258 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/50 (20130101) G06T 2207/20081 (20130101) G06T 2207/30004 (20130101) G06T 2207/30168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301787 | Guo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Ting Guo (Cambridge, Massachusetts); John Patrick Fisher (Kensington, Maryland); Hannah Baker (Baltimore, Maryland); Max Jonah Lerman (Silver Spring, Maryland); Robert Choe (Arlington, Virginia) |
| ABSTRACT | An implantable acellular polymeric scaffold device functionalized with aggrecan is provided. Also provided are methods of fabricating a polymeric scaffold device, including methods of fabricating the scaffold device via 3D printing. Methods of treating a cartilage defect in a subject in need thereof comprise application of the disclosed scaffold device in combination with microfracture procedures. A specialized lid for a centrifugation well plate is also provided. |
| FILED | Friday, May 19, 2023 |
| APPL NO | 18/320760 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/30756 (20130101) Original (OR) Class A61F 2002/30766 (20130101) A61F 2002/30985 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302035 | Ting et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David T. Ting (Dover, Massachusetts); Miguel N. Rivera (Belmont, Massachusetts); Vikram Deshpande (Belmont, Massachusetts); Kshitij Arora (North Quincy, Massachusetts); Benjamin Dylan Greenbaum (New York, New York); Alexander V. Solovyov (New York, New York) |
| ABSTRACT | Methods for predicting response to immunotherapy and selecting immunotherapy for treating cancer, e.g., cancer of epithelial origin, in a subject. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/156434 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302420 | Weitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David A. Weitz (Cambridge, Massachusetts); Mark Romanowsky (Cambridge, Massachusetts); Adam R. Abate (Cambridge, Massachusetts) |
| ABSTRACT | Parallel uses of microfluidic methods and devices for focusing and/or forming discontinuous sections of similar or dissimilar size in a fluid are described. In some aspects, the present invention relates generally to flow-focusing-type technology, and also to microfluidics, and more particularly parallel use of microfluidic systems arranged to control a dispersed phase within a dispersant, and the size, and size distribution, of a dispersed phase in a multi-phase fluid system, and systems for delivery of fluid components to multiple such devices. |
| FILED | Tuesday, November 01, 2022 |
| APPL NO | 17/978304 |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/41 (20220101) B01F 23/4105 (20220101) B01F 33/3011 (20220101) Original (OR) Class B01F 2101/23 (20220101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) B01J 2219/00015 (20130101) B01J 2219/0097 (20130101) B01J 2219/00783 (20130101) B01J 2219/00828 (20130101) B01J 2219/00831 (20130101) B01J 2219/00833 (20130101) B01J 2219/00837 (20130101) B01J 2219/00889 (20130101) B01J 2219/00891 (20130101) B01J 2219/00975 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/8593 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302433 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pu-Xian Gao (Coventry, Connecticut); Son Hoang (Corona, New York) |
| ABSTRACT | Metal oxide nanoarrays, such as titanium oxide nanoarrays, having a platinum group metal dispersed thereon and methods of making such nanoarrays are described. The platinum group metal can be dispersed on the metal oxide nanoarray as single atoms. The nanoarrays can be used to catalyze oxidation of combustion exhaust. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/143559 |
| CURRENT CPC | Separation B01D 53/865 (20130101) B01D 2255/1021 (20130101) B01D 2255/20707 (20130101) B01D 2258/012 (20130101) B01D 2259/4566 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) Original (OR) Class B01J 23/42 (20130101) B01J 35/04 (20130101) B01J 35/0006 (20130101) B01J 35/06 (20130101) B01J 35/0013 (20130101) B01J 35/023 (20130101) B01J 37/10 (20130101) B01J 37/0217 (20130101) B01J 37/344 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302489 | Ryu et al. |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jong Eun Ryu (Raleigh, North Carolina); Chang-Jin Kim (Raleigh, North Carolina); Mohammed A. Zikry (Raleigh, North Carolina) |
| ABSTRACT | Various examples are related to template-free methodologies to obtain “semi-regular” micro/nano-textures utilizing ribbing instability behavior in viscoelastic polymers. The methodologies offer low manufacturing cost and scalability for real-world applications. In one example, a method includes forming a viscoelastic material coating and forming micro-scale and/or nano-scale 3D features on a surface of the viscoelastic material coating. The micro-scale and/or nano-scale 3D features can be formed under shearing stress using a roll-to-roll process without a template. The texture periodicity and height in the polymer coat film can be adjusted through the roll coating process parameters and/or the polymer composite behavior. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/125617 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/12 (20130101) Original (OR) Class B05D 2301/00 (20130101) B05D 2506/10 (20130101) B05D 2518/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302508 | Campanella et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts) |
| ABSTRACT | A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/327638 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302509 | Campanella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts) |
| ABSTRACT | A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/327694 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302530 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Gongyao Zhou (Wilmington, Delaware); Yifan Fei (Philadelphia, Pennsylvania); Jie Xu (Philadelphia, Pennsylvania) |
| ABSTRACT | A device and method of thixotropic mixing and 3D printing of alloys is provided. The method includes the steps of locating a thixotropic mixer having a discharge nozzle above a substrate; adding a molten alloy to the mixer; locating the nozzle between about 1 mm and about 20 mm from the substrate; and extruding the alloy from the nozzle onto the substrate. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/118944 |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/003 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/10 (20200101) B33Y 70/00 (20141201) Alloys C22C 1/02 (20130101) C22C 28/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303472 | SCHNEEBELI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VERMONT (Burlington, Vermont) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Severin T. SCHNEEBELI (South Burlington, Vermont); Jianing LI (South Burlington, Vermont); Mona SHARAFI (Winooski, Vermont) |
| ABSTRACT | The present application is directed to a nanocage of Formula (I): wherein A and R are as described herein. The present application is also directed to a process for preparation of a nanocage of Formula (I). Methods of utilizing the nanocage for detecting an analyte in a fluid and for functionalizing a polymer are also described. |
| FILED | Tuesday, June 01, 2021 |
| APPL NO | 18/007639 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 45/46 (20130101) Original (OR) Class C07C 241/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/25 (20130101) C08K 2201/011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303493 | Conrad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey); SAN JOSE STATE UNIVERSITY RESEARCH FOUNDATION (San Jose, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laura Miller Conrad (Redwood City, California); Martin F. Semmelhack (Princeton, New Jersey); Zinan Zhang (Decatur, Georgia); Minh Tran (San Francisco, California); Lauren Blankenship (College Station, Texas) |
| ABSTRACT | In one aspect, compounds and methods are described herein for treating gram negative bacteria having resistance to cationic antimicrobial peptides. In some embodiments, for example, compounds of formula I are provided. In another aspect, a treatment for a gram negative bacterial infection comprises a cationic antimicrobial protein (CAP) in conjunction with a compound of formula I. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 18/021284 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/12 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 213/75 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303600 | Veige et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam S. Veige (Gainesville, Florida); Ushnish Mandal (Gainesville, Florida); Courtney M. Sever (Gainesville, Florida) |
| ABSTRACT | Provided herein are compounds that can be used as a catalyst to form cyclic polymers, methods of making and using the same. For example, provided herein are compounds of formula (I) or (II): |
| FILED | Friday, May 12, 2023 |
| APPL NO | 18/196977 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 11/00 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 132/08 (20130101) C08F 138/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303635 | MUÑOZ VAN DEN EYNDE |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Victor Emilio MUÑOZ VAN DEN EYNDE (Merced, California) |
| ABSTRACT | The present disclosure provides methods for the identification and quantitation of targets (e.g., biological targets such as cells and viruses) using molecules comprising a binding moiety that binds to the target and a fluorescent moiety whose fluorescence properties are altered when the binding moiety binds to the target. A plurality of said molecules are specifically arranged in structures that resemble the size and shape of a cell to maximize affinity and sensitivity. |
| FILED | Thursday, August 19, 2021 |
| APPL NO | 18/020875 |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/569 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303804 | FINI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elham FINI (Phoenix, Arizona); Shuguang DENG (Mesa, Arizona); Amirul Islam RAJIB (Tempe, Arizona); Kodanda Phani Raj DANDAMUDI (Tempe, Arizona) |
| ABSTRACT | Biochar can be used as an additive for bitumen. A bitumen composite includes bitumen and biochar. The biochar can include biochar from one or more of algae, food waste, animal waste, and cellulose-containing material (e.g., palm sheath). The biochar typically comprises 1 wt % to 20 wt % of the weight of the bitumen composite. The bitumen composite can be combined with aggregate to yield asphalt. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 18/020038 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 11/005 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 95/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303861 | LYNN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David LYNN (Middleton, Wisconsin); Harshit AGARWAL (Madison, Wisconsin) |
| ABSTRACT | The present invention provides slippery liquid-infused porous surfaces (SLIPS), slippery nanoemulsion-infused porous surfaces (SNIPS), lubricant-impregnated surfaces (LIS), and other materials fabricated using polymers, linkers, and/or liquids and emulsions that are degradable (preferably biodegradable) and biocompatible. In addition to having reduced negative environmental effects, these coatings exhibit durable and robust anti-fouling properties against a wide range of substances and organisms, and advance new approaches to the design of biodegradable and sustainable liquid-infused materials. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/189885 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/08 (20130101) C08G 63/78 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1637 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303865 | CHANDA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (ORLANDO, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | DEBASHIS CHANDA (OVIEDO, Florida); DANIEL FRANKLIN (ORLANDO, Florida); Pablo Manuel CENCILLO ABAD (Winter Park, Florida) |
| ABSTRACT | A method is for forming a radiation shield around an object. The method includes providing an inorganic paint pigment comprising a fluid matrix, and paint flakes carried within the fluid matrix. Each paint flake includes a common aluminum mirror layer having a first major surface and a second major surface opposing the first major surface, a first plasmonic aluminum reflector layer carried by the first major surface, and a second plasmonic aluminum reflector layer carried by the second major surface. The method also includes coating an outer surface of the object with the inorganic paint pigment. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/311952 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 9/02 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/0033 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/32 (20130101) Original (OR) Class C09D 7/20 (20180101) C09D 7/62 (20180101) C09D 7/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304000 | Josephs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Josephs (Durham, North Carolina); Dewran Kocak (Durham, North Carolina); Piotr Marszalek (Durham, North Carolina); Charles A. Gersbach (Chapel Hill, North Carolina) |
| ABSTRACT | Disclosed herein are optimized guide RNAs (gRNAs) and methods of designing and using said optimized gRNAs that have increased target binding specificity and reduced off-target binding. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 17/897033 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/10 (20190201) G16B 15/30 (20190201) G16B 25/00 (20190201) G16B 30/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304166 | Zenyuk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Iryna Zenyuk (Irvine, California); Andrea Perego (Irvine, California); Mo Li (Irvine, California); Devashish S. Kulkarni (Irvine, California) |
| ABSTRACT | An electrochemical method for producing calcium hydroxide includes dissolving a calcium precursor in a first solution in contact with a first electrode to produce Ca2+ ions, transporting the Ca2+ ions across a first membrane from the first solution into a second solution using a first electrochemical potential, producing hydroxide ions at a second electrode, transporting the hydroxide ions across a second membrane into the second solution using a second electrochemical potential, and precipitating calcium hydroxide from the second solution. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 18/041189 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 7/48 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 1/16 (20130101) Original (OR) Class C25B 9/21 (20210101) C25B 11/032 (20210101) C25B 11/065 (20210101) C25B 11/077 (20210101) C25B 11/081 (20210101) C25B 13/02 (20130101) C25B 13/08 (20130101) C25B 15/083 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304175 | Zhong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chuan-Jian Zhong (Endwell, New York); Shan Wang (Beaverton, Oregon) |
| ABSTRACT | The present disclosure relates to a method of making one or more PAA-coated silver nanoparticles, including: heating an aqueous solution including a silver source material such as silver nitrate, a reducing agent such as monoethanolamine, and a capping molecule such as PAA under conditions suitable for forming a reaction mixture; and contacting the reaction mixture with an antisolvent to form one or more PAA-coated silver nanoparticles. In embodiments, the present disclosure includes a cathode catalyst, including: one or more substantially monodisperse PAA-coated silver nanoparticles, as well as cathodes and electrochemical cells including the PAA-coated silver nanoparticles. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/102391 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/037 (20210101) C25B 11/065 (20210101) C25B 11/095 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304193 | Franklin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rahul Franklin (West Lafayette, Indiana); Weiheng Xu (Chandler, Arizona); Dharneedar Ravichandran (Tempe, Arizona); Sayli Jambhulkar (Gilbert, Arizona); Yuxiang Zhu (Gilbert, Arizona); Kenan Song (Gilbert, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rahul Franklin (West Lafayette, Indiana); Weiheng Xu (Chandler, Arizona); Dharneedar Ravichandran (Tempe, Arizona); Sayli Jambhulkar (Gilbert, Arizona); Yuxiang Zhu (Gilbert, Arizona); Kenan Song (Gilbert, Arizona) |
| ABSTRACT | A carbonized coaxial composite fiber includes an inner layer including carbonized polyacrylonitrile, a middle layer surrounding the inner layer and including carbonized graphene nanomaterials, and an exterior layer surrounding the middle layer including carbonized polyacrylonitrile. The carbonized graphene nanomaterials are aligned along a length of the coaxial composite fiber. |
| FILED | Friday, December 02, 2022 |
| APPL NO | 18/073975 |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/06 (20130101) D01D 5/34 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 8/08 (20130101) D01F 8/18 (20130101) Original (OR) Class D01F 11/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304916 | Ozdemir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sahin Kaya Ozdemir (St. Louis, Missouri); Lan Yang (St. Louis, Missouri); Bo Peng (St. Louis, Missouri); Faraz Monifi (San Diego, California) |
| ABSTRACT | A method of transmitting at least one optical signal through an add-drop filter includes directing the at least one optical signal into a first tapered optical fiber of the add-drop filter. The add-drop filter includes an active resonator side-coupled between the first tapered optical fiber and a second tapered optical fiber, and the active resonator is doped with at least one rare earth ion. A tuned optical gain is produced by delivering a tuned amount of pump laser energy to the at least one rare earth ion at a sub-lasing level, the tuned optical gain configured to compensate an intrinsic loss of the active resonator. |
| FILED | Tuesday, May 23, 2023 |
| APPL NO | 18/322118 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 21/7746 (20130101) G01N 2021/655 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304934 | Maddox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Mizar Imaging, LLC (Woods Hole, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Samuel Maddox (Chapel Hill, North Carolina); Joel Carter Smith (East Falmouth, Massachusetts); Bryan William Heck (Mebane, North Carolina); Christopher T. Baumann (Dayton, Ohio) |
| ABSTRACT | Methods and systems for imaging a sample using fluorescence microscopy. High resolution lenses can be used for light sheet microscopy by tilting the excitation beam relative to the imaging optical axis. The excitation beam can be tilted using mirrors, instead of lenses, to generate the tilted illumination sheet. In some examples, a light path starts at a top downward-facing cone of light as it emerges from an optic fiber; a first off-axis parabolic mirror collimates in the x-axis, while a second off-axis parabolic mirror collimates in the y-axis, followed by the photomask to create four primary light sheets, which are then focused by a third off-axis parabolic mirror. As the four primary light sheets converge they create an interference pattern at an objective lens. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/125519 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Original (OR) Class G01N 2021/6463 (20130101) G01N 2021/6484 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 17/006 (20130101) G02B 21/06 (20130101) G02B 21/16 (20130101) G02B 27/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304969 | ZHU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Weidong ZHU (Ellicott City, Maryland); Ke YUAN (Halethorpe, Maryland) |
| ABSTRACT | The present invention relates to a three-dimensional (3D) continuously scanning laser Doppler vibrometer (CSLDV) system that contains three laser heads with two scan mirrors for each head and a controller, to conduct full-field scanning of a plate-like or beam-like structure under sinusoidal excitations to measure its 3D vibrations and operating deflection shapes, and method of using same. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/180409 |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/27 (20130101) G01N 29/2418 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304992 | Schulman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rebecca B. Schulman (Baltimore, Maryland); Sisi Jia (Baltimore, Maryland); Siew Cheng Phua (Baltimore, Maryland); Yuta Nihongaki (Baltimore, Maryland); Yizeng Li (Baltimore, Maryland); Michael Pacella (Baltimore, Maryland); Yi Li (Baltimore, Maryland); Abdul Majeed Mohammed (Baltimore, Maryland); Sean X. Sun (Baltimore, Maryland); Takanari Inoue (Baltimore, Maryland) |
| ABSTRACT | Described are conjugates of nucleic acid nanotubes and cells by linking the nanotubes to a cell surface moiety. Devices, kits, systems, and methods comprising the nanotube cell conjugates are also described. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 18/003462 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0006 (20130101) C12N 15/11 (20130101) C12N 2310/51 (20130101) C12N 2310/351 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230305004 | Kamei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Daniel Takashi Kamei (Monterey Park, California); Daniel William Bradbury (Los Angeles, California); Ren Sun (Pacific Palisades, California); Yushen Du (Los Angeles, California); Benjamin Ming Wu (San Marino, California); Jasmine Thanh Trinh (Alameda, California); Milo Ryan (Larkspur, California); Cassandra Marie Cantu (Sylmar, California) |
| ABSTRACT | In various embodiments methods to improve the detection of a lateral-flow immunoassay for the sensitive detection of the SARS-CoV-2 nucleocapsid protein or other analytes, as well as devices that incorporate those methods are provided. |
| FILED | Monday, August 16, 2021 |
| APPL NO | 18/020604 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 1/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54346 (20130101) G01N 33/54388 (20210801) G01N 33/56983 (20130101) Original (OR) Class G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230305082 | Javor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Joshua Javor (Cambridge, Massachusetts); David Bishop (Brookline, Massachusetts); David Campbell (Brookline, Massachusetts); Matthias Imboden (St. Blaise, Switzerland) |
| ABSTRACT | A system and method of effectively measuring a change in a gradient of a magnetic field. The systems include a first magnet and a second magnet mechanically coupled together and aligned along a polarization axis. The first magnet and the second magnet are positioned such that a pair of like magnetic poles of the first magnet and the second magnet face in opposite directions. Further, the first magnet and the second magnet are configured to move along the polarization axis in response to a magnetic field. A sensing system is configured to measure a change in a gradient of the magnetic field based on the movement of the first magnet and second magnet along the polarization axis in response to the magnetic field. |
| FILED | Thursday, May 18, 2023 |
| APPL NO | 18/199185 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/022 (20130101) Original (OR) Class G01R 33/038 (20130101) G01R 33/0052 (20130101) G01R 33/0385 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230305322 | Yin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yadong Yin (Riverside, California); Zhiwei Li (Riverside, California) |
| ABSTRACT | Photonic pigments are disclosed, which include a plurality of magnetic nanorods assembled into tetragonal colloidal crystals. |
| FILED | Monday, March 13, 2023 |
| APPL NO | 18/182596 |
| CURRENT CPC | Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/77 (20130101) C01P 2004/02 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/16 (20130101) C01P 2004/84 (20130101) C01P 2006/42 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/24 (20130101) C09C 3/006 (20130101) C09C 3/10 (20130101) C09C 3/063 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0036 (20130101) G02F 1/0054 (20130101) Original (OR) Class G02F 2202/32 (20130101) G02F 2202/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230305390 | Stowers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Inpria Corporation (Corvallis, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason K. Stowers (Corvallis, Oregon); Alan J. Telecky (Albany, Oregon); Douglas A. Keszler (Corvallis, Oregon); Andrew Grenville (Corvallis, Oregon) |
| ABSTRACT | Stabilized precursor solutions can be used to form radiation inorganic coating materials. The precursor solutions generally comprise metal suboxide cations, peroxide-based ligands and polyatomic anions. Design of the precursor solutions can be performed to achieve a high level of stability of the precursor solutions. The resulting coating materials can be designed for patterning with a selected radiation, such as ultraviolet light, x-ray radiation or electron beam radiation. The radiation patterned coating material can have a high contrast with respect to material properties, such that development of a latent image can be successful to form lines with very low line-width roughness and adjacent structures with a very small pitch. |
| FILED | Monday, May 22, 2023 |
| APPL NO | 18/200125 |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/20 (20130101) G03F 7/0042 (20130101) G03F 7/0043 (20130101) Original (OR) Class G03F 7/327 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24355 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306323 | RUDDELL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin Lyle RUDDELL (Flagstaff, Arizona); Richard RUSHFORTH (Flagstaff, Arizona) |
| ABSTRACT | Systems and methods for producing geospatial data images produce graphical representations of flows of commodities between geographic regions along likely transportation routes and their dependencies. Raw economic and other data associating with discrete geographic locations are combined with data metadata from other sources, including transportation network data. Images may be generated at user-specified degrees of commodity category granularity and geographic granularity and may contain information at significantly higher degree of geographic granularity than the original raw economic data. |
| FILED | Tuesday, May 30, 2023 |
| APPL NO | 18/203497 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0484 (20130101) G06F 16/13 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0631 (20130101) Original (OR) Class G06Q 30/0201 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306874 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yang Wang (Rolla, Missouri); Weixing Hao (Rolla, Missouri); Yue-Wern Huang (Rolla, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Yang Wang (Rolla, Missouri); Weixing Hao (Rolla, Missouri); Yue-Wern Huang (Rolla, Missouri) |
| ABSTRACT | A system and method for simulating a human respiratory system to facilitate investigating the functioning of the respiratory system, such as the generation and effects of secondhand smoke. An aerosol generator, which may include an atomizer, is configured to generate an aerosol. A series of filter media includes, in order, an inhaling extrathoracic filter media, an inhaling tracheobronchial filter media, an alveolar filter media, an exhaling tracheobronchial filter media, and an exhaling extrathoracic filter media. Each filter media includes one or more layers of a material having a fiber diameter and a weight that simulate the corresponding region of the respiratory system. A conduit may be configured to define a path for the aerosol from the aerosol generator through the series of filter media. An instrument, such as a scanning mobility particle sizer, may be used to measure a property of a secondhand aerosol exiting the exhaling extrathoracic filter media. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/189488 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/497 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306960 | Malone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgetown University (Washington, District of Columbia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Patrick S. Malone (Washington, District of Columbia); Maximilian Riesenhuber (Washington, District of Columbia) |
| ABSTRACT | A method for training vibrotactile speech perception in the absence of auditory speech can comprise selecting a first word, generating a first control signal configured to cause at least one vibrotactile transducer to vibrate against a person's body with a first vibration pattern based on the first word, sampling a second word, generating a second control signal configured to cause a vibrotactile transducer to vibrate against the person's body with a second vibration pattern based on the second word, and presenting a comparison between the first word and the second word to the person. An apparatus for training vibrotactile speech perception can comprise array of vibrotactile transducers can be in contact with the person's body. The array of vibrotactile transducers can replicate a vibration pattern based on one or more spoken words. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/204901 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/016 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/02 (20130101) Original (OR) Class G10L 21/16 (20130101) G10L 2021/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20230307153 — FORMATION AND MODIFICATIONS OF CERAMIC NANOWIRES AND THEIR USE IN FUNCTIONAL MATERIALS
| US 20230307153 | YUSHIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sila Nanotechnologies, Inc. (Alameda, California); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gleb YUSHIN (Atlanta, Georgia); Eugene Michael BERDICHEVSKY (Atlanta, Georgia) |
| ABSTRACT | A catalyst-free synthesis method for the formation of a metalorganic compound comprising a desired (first) metal may include, for example, selecting another (second) metal and an organic solvent, with the second metal being selected to (i) be more reactive with respect to the organic solvent than the first metal and (ii) form, upon exposure of the second metal to the organic solvent, a reaction by-product that is more soluble in the organic solvent than the metalorganic compound. An alloy comprising the first metal and the second metal may be first produced (e.g., formed or otherwise obtained) and then treated with the organic solvent in a liquid phase or a vapor phase to form a mixture comprising (i) the reaction by-product comprising the second metal and (ii) the metalorganic compound comprising the first metal. The metalorganic compound may then be separated from the mixture in the form of a solid. |
| FILED | Tuesday, May 16, 2023 |
| APPL NO | 18/318694 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 13/18 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 5/06 (20130101) C01F 7/30 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/16 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/62227 (20130101) C04B 35/62231 (20130101) C04B 35/62236 (20130101) C04B 35/62263 (20130101) C04B 35/62844 (20130101) C04B 35/62884 (20130101) C04B 2235/441 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/06 (20130101) C07F 5/069 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/407 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/45525 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/023 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/403 (20210101) H01M 50/406 (20210101) H01M 50/411 (20210101) H01M 50/431 (20210101) H01M 50/434 (20210101) H01M 50/437 (20210101) H01M 50/451 (20210101) H01M 50/491 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307637 | Andrews et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jessica Andrews (Los Angeles, California); Eric McClure (Los Angeles, California); Brent Melot (Los Angeles, California) |
| ABSTRACT | A fluoride composition configured for fluoride ion intercalation is disclosed, the fluoride composition comprising one of: a) a defect fluoride pyrochlore composition of the general formula AMIIMIIIF6; or b) a fluoride weberite-type composition of the general formula A1-2MM′ F6-7, wherein the oxidation state of M and M′ are such that the composition is charge balanced. An F-ion energy storage cell is disclosed comprising: a first electrode configured for fluoride ion intercalation, wherein the first electrode comprises one of: a defect fluoride pyrochlore composition, or a fluoride weberite-type composition; a second electrode; an electrolyte; and a separator. And a method of manufacturing an F-ion energy storage cell is disclosed comprising forming an F-ion composition configured for fluoride ion intercalation; forming a first electrode from the F-ion composition; and forming a cell having the first electrode, a second electrode, a separator, and an electrolyte. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/100096 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/009 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/582 (20130101) Original (OR) Class H01M 10/054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230309370 | Hanson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenneth Hanson (Tallahassee, Florida); William Oates (Tallahassee, Florida); Drake Beery (Tallahassee, Florida); Eugenia Stanisauskis (Tallahassee, Florida) |
| ABSTRACT | Photopolymers, monomers, compositions including photopolymers and a dopant, and methods, including methods for eliciting a photomechanical response. The dopant may be a triplet sensitizing dopant. The exposing of compositions to the one or more wavelengths of electromagnetic radiation may elicit a photomechanical response via a triplet excited state mechanism. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/189461 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0672 (20130101) Organic electric solid-state devices H10K 30/671 (20230201) H10K 85/141 (20230201) Original (OR) Class H10K 2101/10 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20230301552 | MALLIRES et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Biolinq Incorporated (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyle Reed MALLIRES (San Diego, California); Jonathan Everett KAVNER (San Diego, California); Joshua Ray WINDMILLER (San Diego, California); Netzahualcoyotl ARROYO (Baltimore, Maryland) |
| ABSTRACT | Described herein are variations of a cortisol monitoring system, including a cortisol monitoring device. For example, a cortisol monitoring device may include a skin-penetrating microneedle array for use in measuring cortisol, such as in a continuous manner. The microneedle array may include, for example, at least one microneedle comprising a working electrode comprising a cortisol-sensing aptamer that selectively and reversibly binds to cortisol. The microneedle array may include, for example, at least one microneedle including a tapered distal portion having an insulated distal apex, and an electrode on a surface of the tapered distal portion located proximal to the insulated distal apex. At least some of the microneedles may be electrically isolated such that one or more electrodes is individually addressable. |
| FILED | Thursday, October 27, 2022 |
| APPL NO | 18/050450 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/16 (20130101) A61B 5/14503 (20130101) Original (OR) Class A61B 5/14546 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230301931 | LEONG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kam W. LEONG (New York, New York); Divya BHANSALI (New York, New York); Tianyu LI (New York, New York) |
| ABSTRACT | The nanoparticulate system for delivering treating agents may be used, for example, for treating inflammation, or for treating cancer, such as oral cancer, and associated inflammation The system used in this manner provides a solution to oral cancer and its associated metastasis by providing a targeted therapy to deliver chemotherapeutics. The nanoparticulate system is in the form of cholesterol-modified polyamidoamine-G3 nanoparticles (PAMAM-Chol NPs), which are used as a carrier for at least one drug. The at least one drug may include at least one cancer drug, at least one corticosteroid, at least one anabolic steroid, at least one hormone (natural or synthetic), and combinations thereof. |
| FILED | Monday, August 16, 2021 |
| APPL NO | 18/041618 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 9/5146 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302133 | Ng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew H. Ng (San Francisco, California); Matthew Kim (San Francisco, California) |
| ABSTRACT | Described herein is a therapeutic cell that expresses a fusion protein comprising: (a) a target-binding domain; and (b) a degradation domain, e.g., a degron or E3 ligase-recruiting domain, that is heterologous to the target-binding domain. In the therapeutic cell, binding of the fusion protein to a target protein via the target-binding domain induces degradation of the target protein. The therapeutic cell can be an immunostimulatory cell, an immunoinhibitory cell or a stem cell, for example. Methods of treatment using the cell are also provided. |
| FILED | Tuesday, August 24, 2021 |
| APPL NO | 18/020611 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 39/4611 (20230501) A61K 39/4631 (20230501) Original (OR) Class A61K 39/46433 (20230501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302212 | BRUGGER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NxStage Medical, Inc. (Lawrence, Massachusetts) |
| ASSIGNEE(S) | NxStage Medical, Inc. (Lawrence, Massachusetts) |
| INVENTOR(S) | James M. BRUGGER (Newburyport, Massachusetts); David DESOUZA (Essex, Massachusetts) |
| ABSTRACT | Simple-to-use systems, methods, and devices for priming replacement blood treatment devices, for swapping the blood treatment devices out, for replacing swapped-out blood treatment devices, and other related operations are described. In embodiments, a blood treatment device can be primed while a therapy is still running. When the replacement blood treatment device is needed, the therapy can be stopped momentarily (less than a minute) for the rapid and safe swap of the blood treatment device. Blood loss can be minimized. The down time from therapy can be minimized. |
| FILED | Friday, May 05, 2023 |
| APPL NO | 18/143733 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3629 (20140204) A61M 1/3643 (20130101) Original (OR) Class A61M 1/3644 (20140204) A61M 1/3646 (20140204) A61M 1/3652 (20140204) A61M 1/3672 (20130101) A61M 39/10 (20130101) A61M 2205/702 (20130101) A61M 2205/705 (20130101) A61M 2205/707 (20130101) A61M 2205/3331 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302423 | Bathe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Bathe (Cambridge, Massachusetts); Tyson Shepherd (Louisville, Colorado); Molly Frances Parsons (Cambridge, Massachusetts) |
| ABSTRACT | Methods for designing scaffolded RNA nanostructures of desired shape are described. In some forms, the methods design nucleic acid “staple” sequences that hybridize to a user-defined RNA scaffold and fold it into the desired shape based on A-form helical nucleic acid geometry. In some forms, the methods implement asymmetry in nucleotide positions across two helices of an edge to account for A-form nucleic acid geometry. In preferred forms, crossover asymmetry is implemented in the staples. In other forms, crossover asymmetry is implemented in the RNA scaffold. In other forms, the methods do not introduce crossover asymmetry. Scaffolded RNA nanostructures produced according to the methods including messenger RNAs, replicating RNAs, functional RNAs and other RNA species within the scaffold, staples, or both scaffold and staples are provided. Modified nanostructures including chemically modified nucleotides are also described. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/191723 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00603 (20130101) B01J 2219/00722 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302444 | Ramezani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ODH IP CORP. (New York, New York) |
| ASSIGNEE(S) | ODH IP CORP. (New York, New York) |
| INVENTOR(S) | Mahdi Ramezani (Rockville, Maryland); Akshaya Nair (Rockville, Massachusetts); Gordon Brezicki (Rockville, Maryland); Jonathan Samuel (Rockville, Maryland); Alec Nicewick (Rockville, Maryland); Griffin Whittredge (Rockville, Maryland) |
| ABSTRACT | This disclosure provides systems and methods for the production of formulations of active pharmaceutical ingredients (APIs). In some embodiments, the disclosure provides an automated medicine formulation system comprising a portable and self-contained API formulating apparatus where the API and excipients are formulated to make a drug product meeting drug quality and safety specifications. The automated formulation system produces liquid formulations including, for example, injectable and intravenous medicines. The systems are capable of producing a plurality of individual sterile injectable doses of drug comprising a specific API and excipient(s), which can be formulated on demand in a GMP and FDA acceptable manner. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/189987 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50255 (20130101) Original (OR) Class B01L 2300/0681 (20130101) B01L 2300/0867 (20130101) B01L 2300/0877 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302531 | Darling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army DEVCOM, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kristopher A. Darling (Havre de Grace, Maryland); Billy C. Hornbuckle (Bel Air, Maryland); Blake P. Fullenwider (Round Rock, Texas); Albert M. Ostlind (Aberdeen, Maryland); Anthony J. Roberts (Chesapeake City, Maryland); Anit K. Giri (Abingdon, Maryland) |
| ABSTRACT | A nano-structured alloy material includes a nanoparticle; a matrix phase surrounding the nanoparticle; and an alkali/alkali Earth metal to alter (i) a material property of the nanoparticle, (ii) a material property of the matrix phase, and (iii) an interaction of the nanoparticle with the matrix phase. |
| FILED | Tuesday, March 22, 2022 |
| APPL NO | 17/700653 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/054 (20220101) Original (OR) Class B22F 1/065 (20220101) B22F 2301/10 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Alloys C22C 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303667 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rafi Ahmed (Atlanta, Georgia); Carl Davis (Atlanta, Georgia); Erica Ollmann Saphire (Solana Beach, California) |
| ABSTRACT | This disclosure relates to antibodies and antigen binding fragments that specifically bind Ebola virus particles. In certain embodiments, the antibodies and fragments are capable of treating or preventing an Ebola viral infection. In certain embodiments, the antibodies and antigen binding fragments are also contemplated for diagnostic methods and compositions related thereto. |
| FILED | Friday, June 09, 2023 |
| APPL NO | 18/332291 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/71 (20130101) C07K 2317/72 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/524 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303899 | Wilker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jonathan J. Wilker (West Lafayette, Indiana); Taylor A. Jones (Sandy Springs, Georgia) |
| ABSTRACT | This invention relates to a method for increasing wetting capability of a biomimetic polymer adhesive comprising the step of introducing plurality of phosphate moieties into said biomimetic polymer adhesive. In particular, the present disclosure relates a method to manufacture a biomimetic polymer adhesive with an increased wetting capability by inducing plurality of phosphate moieties by copolymerization of phosphate-containing monomer, such as monoacryloxyethyl phosphate (MAEP), together with other monomers, or by way of post-polymerization chemical derivertizations. The process and the product thereof are within the scope of this disclosure. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 18/023334 |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 143/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303976 | Gros et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Alena Gros (Barcelona, Spain); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed are methods of isolating T cells and TCRs having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Also disclosed are related methods of preparing a population of cells, populations of cells, TCRs, pharmaceutical compositions, and methods of treating or preventing cancer. |
| FILED | Monday, February 27, 2023 |
| APPL NO | 18/174928 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1703 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304007 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yu Liu (Houston, Texas); Robert J. Schwartz (Houston, Texas); Xiaopeng Shen (Houston, Texas); Rui Liang (Houston, Texas); Shreesti Shrestha (Houston, Texas) |
| ABSTRACT | Provided here are compositions and methods of preventing or treating a muscle disorder in a subject, such as muscle wasting, cachexia, sarcopenia and heart failure. The compositions include inhibitors targeting one or more of the H19X-encoded non-coding RNAs. The inhibitors can inhibit expression of one or more of the H19X-encoded non-coding RNAs or inhibit interaction between one or more of the H19X-encoded non-coding RNAs and their natural target mRNA. Also, provided are methods of preventing or treating a muscle disorder in a subject by inducing specific mutations to decrease levels of one or more of the H19X-encoded non-coding RNAs utilizing gene editing tools such as, but not limited to, integrases, CRISPR/Cas nucleases, TALAN nucleases, zinc finger Nucleases, triplex forming oligonucleotides, or combinations thereof. |
| FILED | Sunday, March 26, 2023 |
| APPL NO | 18/190097 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304025 | Belcher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Angela Belcher (Lexington, Massachusetts); William Records (Cambridge, Massachusetts); Nimrod Heldman (Cambridge, Massachusetts) |
| ABSTRACT | A genetically engineered bacteriophage that can be crosslinked to form a solid material, for example, a hydrogel. |
| FILED | Tuesday, July 20, 2021 |
| APPL NO | 18/017139 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/22 (20130101) C12N 11/14 (20130101) C12N 15/70 (20130101) Original (OR) Class C12N 2795/14022 (20130101) C12N 2795/14043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304195 | BOOTH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MONTANA STATE UNIVERSITY (Bozeman, Montana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric J. BOOTH (Bozeman, Montana); Douglas S. CAIRNS (Bozeman, Montana) |
| ABSTRACT | A method and system for producing stretch-broken fiber material includes feeding a fiber material including a plurality of continuous filaments and a continuous carrier film into a stretch breaking apparatus such that the continuous carrier film contacts the fiber material, and breaking at least a portion of the plurality of continuous filaments of the fiber material using the stretch breaking apparatus while the continuous carrier film contacts the fiber material to produce a stretch broken fiber material contacting the continuous carrier film. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 18/042188 |
| CURRENT CPC | Preliminary Treatment of Fibres, e.g for Spinning D01G 1/08 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304197 | FINK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | YOEL FINK (Brookline, Massachusetts); WEI YAN (Singapore, Singapore) |
| ABSTRACT | The acoustic fiber transducer has a piezoelectric domain with Young's modulus, Epiezo, and including a non-centrosymmetric crystalline-phase piezoelectric material and inorganic piezoelectric particles. At least one charge collector domain is in electrical connection with the piezoelectric domain and includes an electrically conductive material operative to collect electrical charge generated in the piezoelectric domain. At least one electrical conductor is in electrical contact with the at least one charge collector domain and includes an electrically conductive material operative to transport electrical charge from a charge collector domain to an end of the acoustic fiber transducer as an electrical signal indicative of input acoustic sound pressure on a matrix of textile fibers that includes the acoustic fiber transducer. Outer acoustic energy transmission material has a Young's modulus Etrans, of 0.3 Pa-500 MPa, for matching vibrational modes of the textile fiber matrix. A ratio of Epiezo/Etrans is between about 5 and about 70,000. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 18/021619 |
| CURRENT CPC | Woven Fabrics; Methods of Weaving; Looms D03D 1/0088 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2201/02 (20130101) D10B 2331/021 (20130101) D10B 2401/16 (20130101) D10B 2401/18 (20130101) D10B 2401/061 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 17/005 (20130101) H04R 2217/01 (20130101) Electric solid-state devices not otherwise provided for H10N 30/857 (20230201) H10N 30/1061 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304405 | Hayes |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Special Aerospace Services, LLC (Boulder, Colorado) |
| ASSIGNEE(S) | Special Aerospace Services, LLC (Boulder, Colorado) |
| INVENTOR(S) | Christopher Hayes (Denver, Colorado) |
| ABSTRACT | Methods and systems for manipulating surface topology of additively manufactured fluid interacting structures, such as additively manufactured heat exchangers or airfoils, and associated additively manufactured articles, are disclosed. In one aspect, an article which interacts with a fluid is imparted with surface topology features which affect performance parameters related to the fluid flow. The topological features may be sequenced, combined, intermixed, and functionally varied in size and form to locally manipulate and co-optimize multiple performance parameters at each or selectable differential lengths along a flow path. The co-optimization method may uniquely prioritize selectable performance parameters at different points along the flow path to improve or enhance overall system performance. Topological features may include design features such as dimples, fins, boundary layer disruptors, and biomimicry surface textures, and manufacturing artefacts such as surface roughness and subsurface porosity distribution and morphology. |
| FILED | Monday, May 22, 2023 |
| APPL NO | 18/200022 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/38 (20130101) B29C 45/2612 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/14 (20130101) Original (OR) Class Jet-propulsion Plants F02K 9/60 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/516 (20130101) Electric Digital Data Processing G06F 30/15 (20200101) G06F 30/28 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304750 | DEFRANZA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NLIGHT, INC. (Camas, Washington) |
| ASSIGNEE(S) | NLIGHT, INC. (Camas, Washington) |
| INVENTOR(S) | Mark J. DEFRANZA (Ridgefield, Washington); Bryce TOKMAKIAN (Portland, Oregon); Eric MARTIN (Vancouver, Washington); Manoj Kanskar (Portland, Oregon) |
| ABSTRACT | Various embodiments provide apparatuses, systems, and methods related to a heat sink with one or more removable inserts. Respective inserts may include one or more fins that define one or more channels for flow of cooling fluid. The fins may be formed of a composite material that is different than a material of the heat sink body. Other embodiments may be described and/or claimed. |
| FILED | Thursday, March 16, 2023 |
| APPL NO | 18/122638 |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/0275 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 9/26 (20130101) Original (OR) Class F28F 21/04 (20130101) F28F 21/085 (20130101) F28F 2275/14 (20130101) F28F 2280/02 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/02423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304766 | Portoghese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Patuxent River, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rocco Portoghese (Winter Park, Florida); Joseph Vanciel (Orlando, Florida) |
| ABSTRACT | A device to capture pressure data from a weapon's handgrip and trigger during live fire, the device comprising a shell that fits around the handgrip, a network of pressure sensors disposed within the shell such that when the shell is on the handgrip and pressure is applied to the handgrip, the network of pressure sensors is able to record the pressure applied to all sides of the handgrip, and a communication assembly that allows data communication between the network of sensors and a computer. |
| FILED | Tuesday, March 22, 2022 |
| APPL NO | 17/700838 |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 31/00 (20130101) F41A 33/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304786 | PRICE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Kenneth D. PRICE (Long Beach, California); Felix T. SASSO (Los Angeles, California) |
| ABSTRACT | A non-contact angular motion measuring device includes a mirror configured to move or rotate about a pivot axis. The device also includes a curved target, circularly symmetric around an axis normal to the mirror. The device further includes at least one pair of sensors configured to emit fields towards the curved target rather than the mirror. |
| FILED | Thursday, March 24, 2022 |
| APPL NO | 17/703617 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/30 (20130101) Original (OR) Class Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304863 | MAJOR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | KEVIN MAJOR (ALexandria, Virginia); Kenneth J. Ewing (Edgewood, Maryland); Robert R. Nicol (Arlington, Virginia); L. Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | A chemical-detecting apparatus includes an array of sensors. Each sensor of the array of sensors is oriented skyward in operation. Each sensor includes a chemical receiver including a plurality of infrared color vision filters cooperating to detect a plurality of infrared color vision signatures. The plurality of infrared color vision signatures respectively correspond to a plurality of chemicals. Each sensor includes a transmitter configured to transmit a detected chemical identifier, based on a detected infrared color vision signature of the plurality of infrared color vision signatures and corresponding to a detected chemical of the plurality of chemicals, to at least one neighboring sensor of the array of sensors. The transmitter is configured to transmit a detected chemical confirmation from the neighboring sensor to a first-identifying sensor of the array of sensors and is configured to transmit a confirmed chemical alarm, based on the detected chemical confirmation, from the first-identifying sensor. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/127279 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/50 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304916 | Ozdemir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sahin Kaya Ozdemir (St. Louis, Missouri); Lan Yang (St. Louis, Missouri); Bo Peng (St. Louis, Missouri); Faraz Monifi (San Diego, California) |
| ABSTRACT | A method of transmitting at least one optical signal through an add-drop filter includes directing the at least one optical signal into a first tapered optical fiber of the add-drop filter. The add-drop filter includes an active resonator side-coupled between the first tapered optical fiber and a second tapered optical fiber, and the active resonator is doped with at least one rare earth ion. A tuned optical gain is produced by delivering a tuned amount of pump laser energy to the at least one rare earth ion at a sub-lasing level, the tuned optical gain configured to compensate an intrinsic loss of the active resonator. |
| FILED | Tuesday, May 23, 2023 |
| APPL NO | 18/322118 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 21/7746 (20130101) G01N 2021/655 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304992 | Schulman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rebecca B. Schulman (Baltimore, Maryland); Sisi Jia (Baltimore, Maryland); Siew Cheng Phua (Baltimore, Maryland); Yuta Nihongaki (Baltimore, Maryland); Yizeng Li (Baltimore, Maryland); Michael Pacella (Baltimore, Maryland); Yi Li (Baltimore, Maryland); Abdul Majeed Mohammed (Baltimore, Maryland); Sean X. Sun (Baltimore, Maryland); Takanari Inoue (Baltimore, Maryland) |
| ABSTRACT | Described are conjugates of nucleic acid nanotubes and cells by linking the nanotubes to a cell surface moiety. Devices, kits, systems, and methods comprising the nanotube cell conjugates are also described. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 18/003462 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0006 (20130101) C12N 15/11 (20130101) C12N 2310/51 (20130101) C12N 2310/351 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230305612 | Paquette et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MITRE Corporation (Bedford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael J. Paquette (Bedford, Massachusetts); Brian D. Marquis (Bedford, Massachusetts) |
| ABSTRACT | Power and electromagnetic fault injection vulnerabilities in an integrated circuit (IC) can be characterized sampling one or more integrated timing sensors in real-time or by equivalent-time sampling. To achieve equivalent-time sampling, a series of fault injection attempts are performed. An array of timing sensors implemented in part of the IC capture a measure of relative propagation delay, which fluctuates proportionally with instantaneous voltage. Increased voltage fluctuation can indicate elevated probability of faults in digital logic. Related apparatus, systems, techniques and articles are also described. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/706186 |
| CURRENT CPC | Electric Digital Data Processing G06F 1/30 (20130101) Original (OR) Class G06F 11/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306161 | Ulu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erva Ulu (Sunnyvale, California); Nurcan Gecer Ulu (Sunnyvale, California); Walter Hsiao (San Mateo, California); Nelaturi Saigopal (Mountain View, California) |
| ABSTRACT | A three-dimensional object model is divided into slices that are targeted for an additive manufacturing process operable to deposit material at a variable deposition size ranging between minimum and maximum printable feature sizes. For each of the slices, a thinning algorithm is applied to contours of the slice to form a meso-skeleton. Topological features of the thinned slice are reduced over a number of passes such that a portion of the meso-skeleton is reduced to a single pixel wide line. Based on the number of passes, a slice-specific printable feature size within the range of the minimum and maximum printable feature sizes is determined. An adjusted slice is formed by sweeping the meso-skeleton with the slice-specific printable feature size. The adjusted slices are assembled into an object model which is used to create a manufactured object. |
| FILED | Wednesday, December 28, 2022 |
| APPL NO | 18/089831 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/00 (20210101) B22F 10/25 (20210101) B22F 10/36 (20210101) B22F 10/80 (20210101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) B29C 64/182 (20170801) B29C 64/209 (20170801) B29C 64/321 (20170801) B29C 64/343 (20170801) B29C 64/393 (20170801) Electric Digital Data Processing G06F 30/23 (20200101) Original (OR) Class G06F 2113/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306785 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Minchul Kim (East Lansing, Michigan); Anil K. JAIN (Okemos, Michigan); Xiaoming LIU (Okemos, Michigan) |
| ABSTRACT | A method of training a facial recognition system with a plurality of image samples of a training set includes determining an image quality of each of the image samples in the training set, assigning a margin function to each of the image samples based on the image quality of each image sample, classifying the image samples, determining a prediction, determining a loss based on the prediction and the margin function, generating gradients based on the loss and changing weights in the classifier based on the gradients. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/125364 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/764 (20220101) G06V 10/993 (20220101) G06V 40/172 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307232 | Robinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Jeremy T. Robinson (Washington, District of Columbia); Jose J. Fonseca Vega (Alexandria, Virginia); Maxim K. Zalalutdinov (Silver Spring, Maryland) |
| ABSTRACT | A crystallographically-oriented metallic film with a two-dimensional crystal layer comprising a substrate, a metal film on the substrate, the two-dimensional crystal layer on the metal film on the substrate, and a tunable microstructure within the two-dimensional crystal layer on the metal film on the substrate, wherein the metal film has crystallographic registry to the two-dimensional crystal layer. |
| FILED | Wednesday, May 17, 2023 |
| APPL NO | 18/198620 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/18 (20130101) B32B 9/007 (20130101) B32B 15/16 (20130101) B32B 15/20 (20130101) B32B 2260/04 (20130101) B32B 2264/107 (20130101) B32B 2305/026 (20130101) B32B 2307/514 (20130101) B32B 2307/704 (20130101) B32B 2307/732 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/02491 (20130101) H01L 21/02505 (20130101) H01L 21/02507 (20130101) H01L 21/02527 (20130101) H01L 21/02595 (20130101) H01L 21/02601 (20130101) H01L 21/02609 (20130101) Original (OR) Class H01L 33/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307604 | DeBlock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Ryan H. DeBlock (Alexandria, Virginia); Debra R. Rolison (Arlington, Virginia); Jeffrey W. Long (Alexandria, Virginia); Zachary G. Neale (Alexandria, Virginia) |
| ABSTRACT | A method of making an electrode by providing a mixture of first particles of silver or silver oxide and second particles of an inorganic porogen, molding the mixture, cohering the mixture to form a green body, demolding the green body, heating the green body to form a monolith, to convert any silver oxide to silver, and to fuse the first particles together, and submerging the monolith in a liquid that removes the second particles. |
| FILED | Friday, June 02, 2023 |
| APPL NO | 18/328020 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/0433 (20130101) Original (OR) Class H01M 10/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307808 | Haralson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachary Haralson (Iowa City, Indiana); Jonathan A. Lovseth (Marion, Iowa); Michael C. Meholensky (Marion, Iowa) |
| ABSTRACT | A radio frequency (RF) transmission line is described. The RF transmission line includes a first ground line, a second ground line, and a signal line disposed on a substrate and forming a coplanar waveguide. A plasma limiter feature is integrated into an internal surface of one or more of the first ground line, the second ground line, and the signal line. The plasma limiter decreases a gap distance between the signal line and the associated ground line. The gap distance is selected, together with a gas pressure, to control a voltage at which the gas within the gap breaks down, targeted at a breakdown power of 1 W across a wide bandwidth. The plasma limiter thus limits a power transmitted by way of the RF transmission line for protecting a sensitive integrated circuit. |
| FILED | Friday, March 25, 2022 |
| APPL NO | 17/704173 |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/14 (20130101) Original (OR) Class Control of Amplification H03G 11/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230308203 | Bell |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center, Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| INVENTOR(S) | Ryan A. Bell (Mount Pleasant, South Carolina) |
| ABSTRACT | The present invention relates to a communication system for receiving electromagnetic radiation (EMR) signals from a plurality of sources or directions. A communication system comprises a transmission section surrounding an antenna section. The transmission section can be made of concentric layers of lens elements, mirror elements, or refraction medium. The layers allow incoming EMR to be directed to the antenna section through reflection or refraction. The antenna section can be made of a plurality of antenna elements such that each antenna element detects incoming EMR signals from different angles of origin even when the signals are received simultaneously. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/706017 |
| CURRENT CPC | Transmission H04B 10/40 (20130101) H04B 10/80 (20130101) H04B 10/501 (20130101) Multiplex Communication H04J 14/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230308263 | Eldefrawy |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karim Eldefrawy (Palo Alto, California) |
| ABSTRACT | A plurality of nodes connected to the plurality of servers that form a broadcasting overlay over a network for performing best effort broadcasting of data through the broadcasting overlay, may receive, from a first computing device of a plurality of computing devices connected to the broadcasting overlay, a first encrypted message and may perform best effort broadcasting of the first encrypted message through the broadcasting overlay to send, in an end-to-end encrypted manner, the first encrypted message to a first service of a plurality of services. The plurality of nodes may also receive, from the plurality of services, a second encrypted message, and may perform best effort broadcasting of the second encrypted message to propagate the second encrypted message through the broadcasting overlay to send, in the end-to-end encrypted manner, the second encrypted message to a second computing device of the plurality of computing devices. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 18/004836 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0825 (20130101) H04L 9/0847 (20130101) Original (OR) Class H04L 2209/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230308286 | Galligan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Galligan (Mount Laurel, New Jersey); John P. Waxler (Dresher, Pennsylvania); Nhan Nguyen (Huntingdon Valley, Pennsylvania) |
| ABSTRACT | A method for increasing validity of digital signatures comprising: receiving a request from a browser to have a user apply a digital signature to a document; verifying that the document complies with a predefined ruleset (e.g., prescribing font colors); presenting the user with the document on a user-computer interface in such a way that the document's entire content is completely reviewable by the user only if the document complies with the predefined ruleset; upon receiving instruction from the user to sign the document, generating a digital signature according to Advanced Encryption Standard (AES) public key infrastructure (PKI) that protects the document in its entirety, as presented to the user in the previous step; enabling the user to perform one or more of printing, sharing, and saving the digitally-signed document in a memory store; and sending the digitally-signed document with the newly-generated signature to the browser. |
| FILED | Wednesday, March 23, 2022 |
| APPL NO | 17/702135 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/006 (20130101) H04L 9/3247 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20230302397 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kunlei Liu (Lexington, Kentucky); Heather Nikolic (Stamping Ground, Kentucky); Xin Gao (Lexington, Kentucky) |
| ABSTRACT | A carbon capture system includes: (a) an absorber having an inorganic solvent carbon dioxide capture section, a water wash section between the organic solvent carbon dioxide capture section and the inorganic solvent carbon dioxide capture section, a flue gas inlet at the organic solvent carbon dioxide capture section and a treated flue gas outlet at the inorganic solvent carbon dioxide capture section, (b) a stripper, (c) a polishing circuit, and (d) a water wash circuit. A related method of carbon capture includes sequentially subjecting the flue gas to (i) organic solvent carbon dioxide capture, (ii) water washing and (iii) inorganic solvent carbon dioxide capture. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/125614 |
| CURRENT CPC | Separation B01D 53/18 (20130101) B01D 53/62 (20130101) B01D 53/78 (20130101) B01D 53/965 (20130101) B01D 53/1406 (20130101) Original (OR) Class B01D 53/1425 (20130101) B01D 53/1475 (20130101) B01D 53/1493 (20130101) B01D 71/36 (20130101) B01D 2251/306 (20130101) B01D 2251/604 (20130101) B01D 2252/103 (20130101) B01D 2252/504 (20130101) B01D 2252/20421 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302433 | Gao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pu-Xian Gao (Coventry, Connecticut); Son Hoang (Corona, New York) |
| ABSTRACT | Metal oxide nanoarrays, such as titanium oxide nanoarrays, having a platinum group metal dispersed thereon and methods of making such nanoarrays are described. The platinum group metal can be dispersed on the metal oxide nanoarray as single atoms. The nanoarrays can be used to catalyze oxidation of combustion exhaust. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/143559 |
| CURRENT CPC | Separation B01D 53/865 (20130101) B01D 2255/1021 (20130101) B01D 2255/20707 (20130101) B01D 2258/012 (20130101) B01D 2259/4566 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) Original (OR) Class B01J 23/42 (20130101) B01J 35/04 (20130101) B01J 35/0006 (20130101) B01J 35/06 (20130101) B01J 35/0013 (20130101) B01J 35/023 (20130101) B01J 37/10 (20130101) B01J 37/0217 (20130101) B01J 37/344 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302727 | DUDUKOVIC et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nikola DUDUKOVIC (Hayward, California); Roger AINES (Livermore, California); Sarah BAKER (Dublin, California); Joshua R. DEOTTE (Livermore, California); Eric B. DUOSS (Danville, California); Jeremy Taylor FEASTER (Fremont, California); Alexandra GOLOBIC (Oakland, California); Julie MANCINI (Livermore, California); Christopher M. SPADACCINI (Oakland, California); Seth Evan WATTS (Collingswood, New Jersey); Michael John TROKSA (Veradale, Washington) |
| ABSTRACT | The present disclosure relates to a method for additively manufacturing a part. The method may involve using a reservoir to hold a granular material feedstock, and using a nozzle in communication with the reservoir to release the granular material feedstock in a controlled fashion from the reservoir to form at least one layer of a part. The method may further involve using an excitation source for applying a signal to the nozzle which induces a controlled release of the granular material feedstock from the nozzle as needed to pattern the granular material feedstock as necessary to form a layer of the part. |
| FILED | Friday, May 19, 2023 |
| APPL NO | 18/199530 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 12/41 (20210101) B22F 12/53 (20210101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/209 (20170801) Original (OR) Class B29C 64/227 (20170801) B29C 64/255 (20170801) B29C 64/268 (20170801) B29C 64/321 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303771 | DONG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tao DONG (Lakewood, Colorado); Cheng ZHANG (Golden, Colorado) |
| ABSTRACT | The present disclosure relates to a composition that includes a structure as defined by where |
| FILED | Monday, March 27, 2023 |
| APPL NO | 18/190850 |
| CURRENT CPC | Heterocyclic Compounds C07D 317/38 (20130101) C07D 407/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 64/0208 (20130101) C08G 71/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303840 | Messman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jamie Michael Messman (Leawood, Kansas); Steven Michael Patterson (Kansas City, Missouri); Petar Dvornic (Midland, Michigan); Alisa Zlatanic (Dexter, Michigan); James Beach (Pittsburg, Kansas) |
| ABSTRACT | Shelf-stable, rapid crosslinking, “all-in-one” pastes useful as “inks” in additive manufacturing are provided. These pastes exhibit desirable rheological flow properties and crosslinking upon exposure to UV light. The pastes are based on vinylsilyl-functionalized, completely amorphous, linear terpolysiloxanes containing predominantly dimethylsiloxy- repeat units with small amounts of diphenylsiloxy-, methylphenylsiloxy-, diethylsiloxy-, and/or methyltrifluoroalkylsiloxy- crystallization disruptors. The base polymers are preferably compounded with a trimethylsilylated-hydrophobic silica filler, thixotropic flow agent, hydrosilyl-functionalized oligomeric crosslinker, and a catalytic system comprising platinum (II) acetylacetonate or trimethyl(methylcyclopentadienyl)-platinum (IV), and diethyl azodicarboxylate. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/312151 |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 83/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303912 | PIRI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohammad PIRI (Laramie, Wyoming); Soheil SARAJI (Laramie, Wyoming); Alvinda Sri HANAMERTANI (Laramie, Wyoming); Keerti Vardhan SHARMA (Laramie, Wyoming); Van Si LE (Laramie, Wyoming); Magda Ibrahim YOUSSIF (Laramie, Wyoming) |
| ABSTRACT | Methods and materials for foam production in enhanced oil recovery operations are described herein. More specifically, embodiments of the present disclosure relate to foaming agents, gas mobility control agents for use in porous media, compositions comprising such agents, methods for using such agents, methods for generating foams, and systems for enhanced oil recovery. In an embodiment, a method for recovery of oil from a porous rock formation is provided. The method includes contacting a foaming fluid and a surfactant solution described herein with the porous rock formation, and generating a foam comprising the foaming fluid and the surfactant solution. The method further includes mobilizing oil from the porous rock formation by contacting the porous rock formation with the foam; and collecting at least a portion of the mobilized oil. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/126194 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/584 (20130101) Original (OR) Class C09K 8/703 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304114 | Rohatgi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aashish Rohatgi (Richland, None); Richard W. Davies (Lenoir City, Tennessee); Mert Efe (West Richland, Washington); Wahaz Nasim (Boston, Massachusetts); Angel Ortiz (Pasco, Washington); Piyush Upadhyay (Richland, Washington); Hrishikesh Das (Richland, Washington); Glenn J. Grant (Benton City, Washington); Elizabeth V. Stephens (Kennewick, Washington) |
| ABSTRACT | Aluminum sheet stamping processes are provided that can include heating an aluminum sheet to a first temperature that is greater than ambient temperature; quenching the aluminum sheet to cool the aluminum sheet to a second temperature that is less than the first temperature; after the quenching allowing the aluminum sheet to rest at ambient temperature for at least 24 hours; and stamping the aluminum sheet to form a stamped component. Stamped aluminum components including one or more portions having an HRB hardness of greater than 87 are also provided. Processes are also provided for fabricating an aluminum component from an aluminum sheet. The processes can include modifying formability of at least one discrete portion of an aluminum sheet, and compressing and/or expanding at least a portion of the one discrete portion to form a fabricated component. The fabricated component can include at least one aluminum member comprising a compressed and/or expanded modified discrete portion. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/126018 |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 8/0236 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304529 | Klemstine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David C. Klemstine (Orion, Michigan); Guirong Cao (Troy, Michigan); Jianghuai Yang (Rochester Hills, Michigan); William A. Berry (Davison, Michigan); Qigui Wang (Rochester Hills, Michigan) |
| ABSTRACT | An automobile vehicle crankshaft including a crankshaft casting of a nodular iron. The crankshaft casting includes multiple main journals coaxially aligned on a common crankshaft casting axis. Multiple crankpin journals are fixedly connected to the main journals by individual webs. Multiple lightening holes have individual ones of the multiple lightening holes integrally formed within individual ones of the crankpin journals during casting. A bubble space is located proximate to a mid-portion of selected ones of the multiple lightening holes of the crankpin journals. The bubble space locally increases a passage size of the selected ones of the multiple lightening holes and reduces a mass of the individual ones of the crankpin journals. |
| FILED | Friday, March 25, 2022 |
| APPL NO | 17/704524 |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 19/0072 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 3/08 (20130101) F16C 3/14 (20130101) F16C 9/02 (20130101) Original (OR) Class F16C 2202/06 (20130101) F16C 2202/08 (20130101) F16C 2204/60 (20130101) F16C 2220/02 (20130101) F16C 2360/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304647 | Gladden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Glint Photonics, Inc. (Burlingame, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Gladden (San Mateo, California); Andrew Kim (San Jose, California); Peter Kozodoy (Palo Alto, California); Barbara Kruse (San Francisco, California) |
| ABSTRACT | A luminaire for providing configurable static lighting or dynamically-adjustable lighting. The luminaire uses an array of focusing elements that act on light provided via a corresponding array of sources or via an edge-lit lightguide. Designs are provided for adjusting the number of distinct beams produced by the luminaire, as well as the angular width, angular profile, and pointing angle of the beams. Designs are also provided for systems utilizing the adjustable luminaires in various applications. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/143117 |
| CURRENT CPC | Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 9/61 (20160801) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 5/007 (20130101) F21V 7/0008 (20130101) F21V 14/06 (20130101) Original (OR) Class F21V 17/02 (20130101) Optical Elements, Systems, or Apparatus G02B 3/0006 (20130101) G02B 6/005 (20130101) G02B 6/0036 (20130101) G02B 6/0055 (20130101) G02B 19/0028 (20130101) G02B 19/0066 (20130101) G02B 26/0875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304690 | Simmons et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Onboard Data, Inc. (Somerville, Massachusetts) |
| ASSIGNEE(S) | Onboard Data, Inc. (Somerville, Massachusetts) |
| INVENTOR(S) | Brian Simmons (Somerville, Massachusetts); Jose R. Vazquez-Canteli (Bastrop, Texas) |
| ABSTRACT | Techniques for determining point type, equipment type, equipment instance, and equipment relationship for different points associated with pieces of equipment located at a building is described. The techniques may include obtaining data corresponding to point(s) associated with one or more pieces of equipment located at a building controlled by a building control network, and using the data and statistical model(s) to determine point type(s), equipment type(s), and/or equipment instance(s) for the point(s). The techniques may include determining operational relationships between different pieces of equipment located at the building. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 18/018376 |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/49 (20180101) F24F 11/63 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304907 | PIRI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohammad PIRI (Laramie, Wyoming); Yun XIE (Laramie, Wyoming); Keerti Vardhan SHARMA (Laramie, Wyoming); Van Si LE (Laramie, Wyoming); Magda Ibrahim YOUSSIF (Laramie, Wyoming); Alvinda Sri HANAMERTANI (Laramie, Wyoming); Omar ELKHATIB (Laramie, Wyoming); Kaustubh Shriram RANE (Laramie, Wyoming) |
| ABSTRACT | Embodiments of the present disclosure generally relate to apparatus and methods for foam generation, and to apparatus and methods for evaluation of foam systems. In an embodiment, a method of analyzing foam properties includes delivering a foaming composition and a gas to a housing at a pressure of 500 psi to 6,000 psi and a temperature of 35° C. to 150° C., the housing containing an unconsolidated porous media. The method further includes flowing the foaming composition and the gas through the housing, and forming a foam by an interaction of the foaming composition, the gas, and the unconsolidated porous media. The method further includes directing the foam from the housing to a visualization chamber, the visualization chamber in fluid communication with the housing, and measuring a foam characteristic via the visualization chamber. The characteristic may include foam half-life, pressure drop through the unconsolidated media, and/or apparent viscosity of the foam. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/126168 |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/235 (20220101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/0037 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/164 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 7/10 (20130101) Original (OR) Class G01N 11/00 (20130101) G01N 2011/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230305359 | Demory et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brandon Demory (Tracy, California); Tiziana C. Bond (Livermore, California); Clint Frye (Livermore, California); Lars Voss (Livermore, California) |
| ABSTRACT | Amorphous silicon carbide may be doped with one or more ions such as vanadium and these ions may radiate light if excited, for example, using optical or electrical pumping. A single photon light source may be formed from a single such ion that is pumped or from a plurality of ions that are pumped if light from only one ion is collected, e.g., using an aperture or pin hole. Such single photon sources may possibly be use in quantum computing, quantum sensing and/or quantum telecommunications. |
| FILED | Tuesday, March 22, 2022 |
| APPL NO | 17/655983 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/956 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/54 (20130101) C01P 2004/03 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/698 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 2/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306085 | Paglieroni |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David W. Paglieroni (Pleasanton, California) |
| ABSTRACT | A system is provided for background suppression and anomaly detection/classification in a sensor data field using an omnidirectional stochastic technique to expose anomalies. For each element in the sensor data field, the system identifies neighborhoods of elements that cover the various nearby parts of the sensor data field in all directions. At a specified statistical significance level for background, the system considers the element to be background if it is statistically insignificant relative to the elements in any one of the surrounding neighborhoods. The system exposes anomalous objects by applying an attenuation coefficient near zero to those background elements. The system grows anomalous objects from seed elements that correspond to local peaks in the background-suppressed sensor data field. The system can be trained to jointly learn an effective statistical significance level for background suppression and the parameters for classifying objects as of interest or not of interest. |
| FILED | Friday, March 25, 2022 |
| APPL NO | 17/656496 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2237 (20190101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0053 (20130101) Original (OR) Class G06K 9/00536 (20130101) G06K 9/6264 (20130101) G06K 9/6276 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230306152 | Gering |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin L. Gering (Idaho Falls, Idaho) |
| ABSTRACT | Embodiments disclosed herein include a method of analyzing changes in a system that occur over time. A battery is an example of such a system. The changes may result from discrete interactions. The method may include defining an electrode of a battery. The method may also include obtaining an expression for discrete interactions between the electrode and one or more of a solvent, a salt component, and an event that affects the battery. The method may also include modeling the discrete interactions between the electrode and the one or more of the solvent, the salt component, and the event. The method may also include obtaining, based on the modeling of the discrete interactions, an aging profile. The aging profile may be indicative of changes in the battery resulting from the discrete interactions. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 18/001304 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307566 | LANCE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAXEON SOLAR PTE. LTD. (Singapore, Singapore) |
| ASSIGNEE(S) | MAXEON SOLAR PTE. LTD. (SINGAPORE, Singapore) |
| INVENTOR(S) | Tamir LANCE (Los Gatos, California); Nathan Beckett (Oakland, California); Gilad Almogy (Palo Alto, California); David B. DeGraaff (Mountain View, California) |
| ABSTRACT | A high efficiency configuration for a solar cell module comprises solar cells arranged in an overlapping shingled manner and conductively bonded to each other in their overlapping regions to form super cells, which may be arranged to efficiently use the area of the solar module. |
| FILED | Thursday, March 16, 2023 |
| APPL NO | 18/122384 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/028 (20130101) H01L 31/043 (20141201) H01L 31/044 (20141201) H01L 31/0504 (20130101) H01L 31/0516 (20130101) Original (OR) Class H01L 31/02008 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/36 (20141201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307637 | Andrews et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jessica Andrews (Los Angeles, California); Eric McClure (Los Angeles, California); Brent Melot (Los Angeles, California) |
| ABSTRACT | A fluoride composition configured for fluoride ion intercalation is disclosed, the fluoride composition comprising one of: a) a defect fluoride pyrochlore composition of the general formula AMIIMIIIF6; or b) a fluoride weberite-type composition of the general formula A1-2MM′ F6-7, wherein the oxidation state of M and M′ are such that the composition is charge balanced. An F-ion energy storage cell is disclosed comprising: a first electrode configured for fluoride ion intercalation, wherein the first electrode comprises one of: a defect fluoride pyrochlore composition, or a fluoride weberite-type composition; a second electrode; an electrolyte; and a separator. And a method of manufacturing an F-ion energy storage cell is disclosed comprising forming an F-ion composition configured for fluoride ion intercalation; forming a first electrode from the F-ion composition; and forming a cell having the first electrode, a second electrode, a separator, and an electrolyte. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/100096 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/009 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/582 (20130101) Original (OR) Class H01M 10/054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307729 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Christopher S. Johnson (Naperville, Illinois); Anna Lee (Darien, Illinois) |
| ABSTRACT | A process for charging a discharged electrochemical cell includes applying a voltage bias to the discharged electrochemical cell; and illuminating the cathode with a light source. |
| FILED | Thursday, May 11, 2023 |
| APPL NO | 18/196350 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/44 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/028 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/00 (20130101) H02J 7/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307909 | Schneider et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Kevin P. Schneider (Seattle, Washington); Xueqing Sun (Richland, Washington); Francis K. Tuffner (Shoreline, Washington); Wei Du (Richland, Washington); Marcelo A. Elizondo (Seattle, Washington); Jing Xie (Bellevue, Washington) |
| ABSTRACT | Electric power systems, control systems and associated operational methods are described. According to one aspect, an electric power system includes plural load controllers that are configured to control the supply of electrical energy from the system to plural loads, a control system that determines an amount of power in reserve and available to be provided to the electric power system, uses the determined amount of power in reserve to determine different values for a plurality of setpoints that correspond to a parameter of electrical energy that is supplied by the system to the loads, and the load controllers monitor the parameter of the electrical energy that is supplied by the system with respect to the setpoint values and to adjust an amount of the electrical energy that is supplied from the electric power system to the loads as a result of the monitoring of the parameter by the load controllers. |
| FILED | Wednesday, March 22, 2023 |
| APPL NO | 18/124777 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/06 (20130101) Original (OR) Class H02J 13/00002 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230309213 | Selter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Matthew Selter (Blue Springs, Missouri); Michael Alan Walsh (Overland Park, Kansas) |
| ABSTRACT | A multi-layer coating on an outer surface of a substrate includes a first layer applied directly to the outer surface of the substrate. The first layer includes diamond-like carbon (DLC) configured to mitigate metal whisker formation. A second layer is applied on a top surface of the first layer. The second layer is a conformal coating that includes a second material configured to bind to the top surface of the first layer and fill any microfractures that may form in the first layer. Optionally, a third layer is applied on a top surface of the second layer and includes DLC configured to protect the second layer from oxidation and degradation. |
| FILED | Wednesday, May 31, 2023 |
| APPL NO | 18/326672 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0218 (20130101) Original (OR) Class H05K 2201/0175 (20130101) H05K 2201/0715 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20230301338 | KOZUBAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. KOZUBAL (Bozeman, Montana); Richard E. MACUR (Manhattan, Montana); Yuval C. AVNIEL (Missoula, Montana); Maximilian DeVane HAMILTON (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Friday, May 19, 2023 |
| APPL NO | 18/320469 |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302034 | Grindrod et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shuttle Pharmaceuticals, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott Grindrod (Rockville, Maryland); Mira Jung (Rockville, Maryland); Olga Timofeeva (Rockville, Maryland); Milton Brown (Rockville, Maryland); Anatoly Dritschilo (Rockville, Maryland) |
| ABSTRACT | Methods and formulations are provided for treating cancer and neoplastic diseases in conjunction with radiation therapy where such methods and formulations include a combination of a radiosensitizing agent that is metabolized by thymidine phosphorylase and a thymidine phosphorylase inhibitor that increases the half-life of the radiosensitizing agent. |
| FILED | Sunday, April 02, 2023 |
| APPL NO | 18/194648 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) A61K 31/7072 (20130101) Original (OR) Class A61K 33/243 (20190101) A61K 2121/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302508 | Campanella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts) |
| ABSTRACT | A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/327638 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302509 | Campanella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts) |
| ABSTRACT | A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/327694 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303584 | Ouyang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SUVALENT THERAPEUTICS INC. (Thousand Oaks, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaohu Ouyang (Rosemead, California); Miles Douglas Kubota (Monravia, California); Andrew Stewart Tasker (Simi Valley, California); Fang-Tsao Hong (Thousand Oaks, California); Mary Walton (Camarillo, California); Victor J. Cee (Thousand Oaks, California) |
| ABSTRACT | The present invention relates to compounds and compositions capable of acting as inhibitors of small ubiquitin-like modifier (SUMO) family of proteins. The compounds and compositions may be used in the treatment of cancer. There are disclosed, inter alia, methods of inhibiting an E1 enzyme, and compounds useful for inhibiting an E1 enzyme. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/793191 |
| CURRENT CPC | Heterocyclic Compounds C07D 495/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20230301296 | Dhingra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amit Dhingra (Pullman, Washington); Seanna L. Hewitt (Pullman, Washington); Evan C. Stowe (Pullman, Washington) |
| ABSTRACT | Methods of controlling the maturation of plants and/or plant products (e.g. fruit, vegetable, ornamentals, etc.) by manipulating Alternative Oxidase (AOX) activity. An increase in activity hastens the maturation process while a decrease in activity slows or stops maturation. |
| FILED | Wednesday, May 31, 2023 |
| APPL NO | 18/204350 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 3/00 (20130101) Original (OR) Class A01N 27/00 (20130101) A01N 37/42 (20130101) Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 7/144 (20130101) A23B 7/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302189 | Catchmark et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Jeffrey M. Catchmark (State College, Pennsylvania); Yuzhi Deng (University Park, Pennsylvania) |
| ABSTRACT | A composite material is formed by combining an expandable polymer having a charge with another polymer having an opposite charge to produce. In particular, the composite material can be prepared by combining the polymers with a medium such as and water, and expanding the mixture using a treatment that expands the mixture to produce, for example, insoluble porous foam-like composite |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/110262 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/28 (20130101) Original (OR) Class A61L 15/425 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 44/3415 (20130101) B29C 48/022 (20190201) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2003/00 (20130101) B29K 2401/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/0061 (20130101) Compositions of Macromolecular Compounds C08L 3/02 (20130101) C08L 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230305000 | ZHAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | WEI ZHAO (FORT PIERCE, Florida); RANDALL G. CAMERON (Homosassa, Florida) |
| ABSTRACT | The invention relates to systems and methods for the determination of degree and distribution of pectin homogalacturonan (HG) methyl-esterification. The systems comprise a sheet, at least one labeled anti-pectin detection antibody, and a Template Guide. The sheet may comprise an absorbent portion and a membrane portion; an absorbent portion, a membrane portion, and a conjugate portion; or an absorbent portion, a membrane portion, a conjugate portion, and a sample portion. The membrane portion comprises a Control Zone with at least one immobilized unlabeled capture reagent and a Test Zone with at least one immobilized unlabeled anti-pectin capture antibody. When the sheet comprises a conjugate portion, the at least one labeled anti-pectin detection antibody is on the conjugate portion. The system may optionally comprise a container with the at least one labeled anti-pectin detection antibody. |
| FILED | Tuesday, March 22, 2022 |
| APPL NO | 17/700713 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 2200/16 (20130101) B01L 2300/0825 (20130101) B01L 2300/0832 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/558 (20130101) G01N 33/54306 (20130101) G01N 33/54366 (20130101) G01N 33/54391 (20210801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20230301741 | Cornelius et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by Department of Veterans Affairs (Washingyon, District of Columbia); The Texas A and M University System (Colleg Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lisa K. Cornelius (Round Rock, Texas); Chetan Jinadatha (Belton, Texas) |
| ABSTRACT | A mobile personal protective equipment (PPE) station can comprise a frame that is configured to be movable on a floor surface and a shield that is coupled to the frame. The shield can comprise a front wall that extends along a first horizontal axis. The front wall can define a pair of arm holes. At least a portion of the front wall can be transparent. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 18/020771 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 90/05 (20160201) Original (OR) Class Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 10/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302018 | Laskin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Debra L. Laskin (Basking Ridge, New Jersey); Jaclynn A. Meshanni (Hawthome, New Jersey); Grace L. Guo (Beidgewater, New Jersey); Andrew J. Gow (Princeton, New Jersey); Jeffrey D. Laskin (Piscataway, New Jersey) |
| ABSTRACT | A method of treating reduced pulmonary function by administering an effective dose of a Farnesoid X Receptor (FXR) agonist, particularly obeticholic acid, is disclosed. Also disclosed is an in vivo animal model of lung injury and altered functioning, useful for identifying compounds active in restoring pulmonary function. |
| FILED | Monday, March 27, 2023 |
| APPL NO | 18/190680 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230303198 | Higgins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian Higgins (Washington, District of Columbia) |
| ABSTRACT | Methods, systems, and apparatuses are described that are configured for determining a forward path of a transportation device, receiving sensor data, determining, based on the sensor data, one or more objects in the forward path of the transportation device, and causing output of audio and tactile feedback to enable an operator of a transportation device to avoid the one or more objects. |
| FILED | Wednesday, March 22, 2023 |
| APPL NO | 18/188052 |
| CURRENT CPC | Cycle Saddles or Seats; Auxiliary Devices or Accessories Specially Adapted to Cycles and Not Otherwise Provided For, e.g Article Carriers or Cycle Protectors B62J 45/41 (20200201) B62J 45/42 (20200201) B62J 50/22 (20200201) Original (OR) Class Rider Propulsion of Wheeled Vehicles or Sledges; Powered Propulsion of Sledges or Cycles; Transmissions Specially Adapted for Such Vehicles B62M 6/50 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/931 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20230301338 | KOZUBAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. KOZUBAL (Bozeman, Montana); Richard E. MACUR (Manhattan, Montana); Yuval C. AVNIEL (Missoula, Montana); Maximilian DeVane HAMILTON (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Friday, May 19, 2023 |
| APPL NO | 18/320469 |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230302437 | Timm et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Jennifer Timm (North Brunswick, New Jersey); Paul G. Falkowski (Princeton, New Jersey); Vikas Nanda (Highland Park, New Jersey); Alexei M. Tyryshkin (Yardley, Pennsylvania); Saroj Poudel (New Brunswick, New Jersey); Joshua A. Mancini (North Royalton, Ohio); Douglas H. Pike (New Brunswick, New Jersey) |
| ABSTRACT | Compositions and methods for hydrogen production are disclosed. |
| FILED | Wednesday, October 19, 2022 |
| APPL NO | 18/047822 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/1805 (20130101) Original (OR) Class B01J 35/004 (20130101) B01J 2231/005 (20130101) B01J 2531/0208 (20130101) B01J 2531/847 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/22 (20130101) C01B 2203/0277 (20130101) C01B 2203/1058 (20130101) C01B 2203/1211 (20130101) Peptides C07K 7/08 (20130101) C07K 2319/60 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/02 (20130101) C12M 21/04 (20130101) C12M 29/04 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304945 | ZEINOLABEDINZADEH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Saeed ZEINOLABEDINZADEH (Chandler, Arizona); Ebrahim AL SERAGI (Mesa, Arizona); Paul GOLDSMITH (Topanga, California) |
| ABSTRACT | A compact, low-power, high image rejection sideband separation receiver is provided. The receiver observes an input radio frequency (RF) signal of multiple spectral lines (spectral observation), then downconverts the signals to intermediate frequency (IF), and then separates the signals to be observed simultaneously in multiple channels. An embodiment is used to observe a signal (G-band) with two spectral lines and utilizes a two stage Weaver architecture to downconvert the signal's frequency, including a combination of mixers in the second stage that achieves the separation of two different channels. |
| FILED | Tuesday, November 29, 2022 |
| APPL NO | 18/059932 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
20230305289 — METHOD TO THERMO-REVERSIBLY CONTROL LIGHT AND HEAT FLOW WITH BICONTINUOUS MICRO-DOMAIN
| US 20230305289 | Xi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Delaware (Newark, Delaware); Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware); Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Yuyin Xi (San Jose, California); Yun Liu (Gaithersburg, Maryland) |
| ABSTRACT | A dynamically tunable composition, a device including the composition, a method of dynamically tuning radiation transmission through the composition, and a method of thermo-reversibly controlling operation of a filter formed from the composition. The composition includes a plurality of nanoparticles dispersed in a single phase region of a binary solvent systems composed of a first solvent and a second solvent, the nanoparticles having a preferential wettability to the first solvent. Changing temperature of the composition causes it to transition thermo-reversibly from the liquid state to a gel state having bi-continuous domains, including a particle domain and a solvent domain. The particle domain features nanoparticles dispersed in a first-solvent-rich fraction of the binary solvent system, and the solvent domain is a second-solvent-rich fraction of the binary solvent system. Exemplary devices incorporating the composition include a filter, a temperature sensor, a smart window, a smart display, a battery, and a tissue growth scaffold. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 18/017106 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/00 (20130101) Optical Elements, Systems, or Apparatus G02B 26/004 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20230307103 | Wilkinson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Thomas Wilkinson (Avenue, Maryland) |
| ABSTRACT | Systems and methods are described, and an example system includes an AI enhanced multi-source health data integration logic that receives a first source electronic health record (EHR) data from a first EHR system and a second source EHR data from a second EHR system, and transforms, according to a knowledge representation schema, health-related information content of the first source EHR data and the second source EHR data to a first source transformed health data and second source transformed health data. The system includes a collaboration platform, configured to host a multi-source transformed health data database, including the transformed first source health data and the transformed second source health data, and hosts AI-enhanced, multiple level telecollaborative analyses by a plurality of participants of the multi-source transformed health data database, generating health management data. |
| FILED | Monday, May 22, 2023 |
| APPL NO | 18/200227 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/20 (20190101) G06F 16/25 (20190101) G06F 16/254 (20190101) G06F 17/40 (20130101) G06F 21/6245 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/00 (20130101) G06Q 90/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) Original (OR) Class G16H 40/67 (20180101) G16H 50/20 (20180101) G16H 80/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
European Union (EU)
| US 20230305167 | Gomez Casco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The European Union, Represented by the European Commission (Brussels, Belgium) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Gomez Casco (Leiden, Netherlands); Gonzalo Seco Granados (Barcelona, Spain); Jose Antonio Lopez Salcedo (Barcelona, Spain); Ignacio Fernanez Hernandez (Brussels, Belgium) |
| ABSTRACT | A computer-implemented method is for detecting Global Navigation Satellite System (GNSS) signal spoofing. The method includes storing sample sequences of the predictable part and of the unpredictable part of a GNSS signal at a GNSS receiver. The predictable part includes predictable bits and the unpredictable part includes unpredictable bits. The value of the unpredictable bits from which the unpredictable sample sequences are extracted is verified. A first and a second partial correlation between the unpredictable, respectively predictable, sample sequences and a locally stored GNSS signal replica are computed. A predefined metric from the complex valued partial correlations is calculated. The predefined metric is compared with a predefined threshold value. In a zero-delay replay attack, the spoofer estimates the unpredictable bits introduced by a GNSS authentication protocol and introduces distortion into the signal. Detecting this distortion indicates whether the signal under analysis is being spoofed or is authentic. |
| FILED | Monday, July 12, 2021 |
| APPL NO | 18/007041 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/115 (20190801) G01S 19/215 (20130101) Original (OR) Class G01S 19/243 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20230302527 | Layman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronald Curtis Layman (Tucson, Arizona); Damian C. Athey (Tucson, Arizona) |
| ABSTRACT | A fastener insert includes a hollow shaft extending in an axial direction. The hollow shaft is configured to receive a threaded fastener at a first axial end of the hollow shaft. The fastener insert also includes a supporting flange extending radially outward from a second axial end of the hollow shaft. The hollow shaft includes an internally threaded shaft portion. The internally threaded shaft portion is configured to secure the threaded fastener received in the hollow shaft. The hollow shaft also includes a resilient shaft portion formed as a unitary single piece with the internally threaded shaft portion. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/705902 |
| CURRENT CPC | Forging; Hammering; Pressing Metal; Riveting; Forge Furnaces B21J 15/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304413 | Chuong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Conway Chuong (Manchester, Connecticut); Caroline A. Karanian (West Hartford, Connecticut); Joey Wong (Enfield, Connecticut) |
| ABSTRACT | A retention ring for a gas turbine engine according to an example of the present disclosure includes, among other things, a main body extending in a circumferential direction about an axis to establish a continuous hoop having a first diameter and a second diameter. The main body includes first and second circumferential faces along opposite sides of the main body. The first circumferential face is dimensioned to abut a gas turbine engine component. The main body includes at least one removal feature dimensioned to sever in response to engagement with a cutting tool. A method of assembly is also disclosed. |
| FILED | Tuesday, March 22, 2022 |
| APPL NO | 17/700682 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/003 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2240/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230304443 | Beinor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Michael A. Beinor (Vernon, Connecticut); Timothy J. Castaldo (Wethersfield, Connecticut); Christopher M. Valva (Manchester, Connecticut); Nasr A. Shuaib (Watertown, Massachusetts); Mitchell D. Panton (Atlanta, Georgia) |
| ABSTRACT | A turbomachine has a bearing in a bearing compartment. A first seal system isolates the bearing compartment and has: a first runner; a second runner; an inner seal encircling the first runner; and an outer seal encircling the second runner. The inner seal has a static clearance with the first runner. The outer seal has a static clearance with the second runner, greater than the inner seal static clearance. The first runner has an inner portion cantilevered inward. The second runner has an outer portion cantilevered outward. |
| FILED | Tuesday, November 22, 2022 |
| APPL NO | 17/992019 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/183 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) F02C 7/28 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/55 (20130101) F05D 2260/98 (20130101) F05D 2260/232 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230307533 | Frey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin M. Frey (Windsor Mill, Maryland); Ken Nagamatsu (Gaithersburg, Maryland); Josephine Chang (Ellicott City, Maryland); Robert S. Howell (Silver Spring, Maryland) |
| ABSTRACT | A field effect transistor, comprising: a substrate and a superlattice of stacked conducting channels on the substrate; a source and a drain spaced-apart from each other on the superlattice; alternating castellations and trenches formed in the superlattice between the source and the drain, wherein the castellations have sidewalls that cut-down through the superlattice to form the trenches and edges of the stacked conducting channels that terminate at the sidewalls; a fringe field dielectric that fills lower volumes of the trenches up to a height on the sidewalls that is higher than first edges of first conducting channels among the stacked conducting channels, such that the fringe field dielectric is adjacent to the first edges; and a gate electrode overlaying the fringe field dielectric and the castellations such that the gate electrode is not adjacent to the first edges. |
| FILED | Wednesday, March 23, 2022 |
| APPL NO | 17/702334 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/155 (20130101) H01L 29/205 (20130101) H01L 29/401 (20130101) H01L 29/2003 (20130101) H01L 29/7785 (20130101) Original (OR) Class H01L 29/42316 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20230308879 | Mani |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maya Mani (Chandler, Arizona) |
| ABSTRACT | An apparatus and system for determining and identifying communication signals are described. Characteristics of the waveform for received signals are determined. Statistical and/or Cyclostationary Signal Processing algorithms are used on the characteristics to identify each signals as a communication signal having a particular protocol. Autocorrelation, spectral correlation, and power Cepstrum, among others, are used to identify the signal using periodic characteristics of the waveform in the frequency domain. Rogue devices that do not adhere to the protocol are identified and actions taken accordingly. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/705611 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0048 (20130101) Wireless Communication Networks H04W 12/73 (20210101) H04W 12/77 (20210101) H04W 12/79 (20210101) H04W 12/122 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, September 28, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20230928.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page