FedInvent™ Patents
Patent Details for Tuesday, January 03, 2023
This page was updated on Wednesday, January 04, 2023 at 03:33 AM GMT
Department of Health and Human Services (HHS)
| US 11540550 | Longo et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Valter D. Longo (Playa Del Rey, California); In Young Choi (Los Angeles, California) |
| ABSTRACT | A method for treating autoimmune and/or inflammatory diseases includes a step of identifying a subject having a gastrointestinal autoimmune/inflammatory disease. A fasting mimicking diet (FMD) is administered to the subject for a first time period. |
| FILED | Thursday, May 11, 2017 |
| APPL NO | 15/592705 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/00 (20160801) A23L 33/30 (20160801) Original (OR) Class A23L 33/40 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) A23V 2200/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11540714 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zhongping Chen (Irvine, California); Youmin He (Irvine, California); Yueqiao Qu (Irvine, California) |
| ABSTRACT | Retinal diseases, such as age-related macular degeneration (AMD), are the leading cause of blindness in the elderly population. Since no known cures are currently present, it is crucial to diagnose the condition in its early stages so that disease progression is monitored. Systems and methods for detecting and mapping the mechanical elasticity of retinal layers in the posterior eye are disclosed herein. A system including confocal shear wave acoustic radiation force optical coherence elastography (SW-ARF-OCE) is provided, wherein an ultrasound transducer and an optical scan head are co-aligned to facilitate in-vivo study of the retina. In addition, an automatic segmentation algorithm is used to isolate tissue layers and analyze the shear wave propagation within the retinal tissue to estimate mechanical stress on the retina and detect early stages of retinal diseases based on the estimated mechanical stress. |
| FILED | Friday, May 03, 2019 |
| APPL NO | 16/402591 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/102 (20130101) A61B 3/1225 (20130101) Original (OR) Class A61B 5/7264 (20130101) A61B 8/10 (20130101) A61B 8/485 (20130101) A61B 8/488 (20130101) A61B 8/4488 (20130101) A61B 8/4494 (20130101) A61B 8/5261 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6224 (20130101) Image Data Processing or Generation, in General G06T 7/12 (20170101) G06T 2207/10101 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/20116 (20130101) G06T 2207/20221 (20130101) G06T 2207/30041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11540740 | Nencka et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE MEDICAL COLLEGE OF WISCONSIN, INC. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Andrew S. Nencka (Greendale, Wisconsin); Andrzej Jesmanowicz (Brookfield, Wisconsin); James S. Hyde (Dousman, Wisconsin); Eric S. Paulson (Jackson, Wisconsin); Lutfi Tugan Muftuler (Menomonee Falls, Wisconsin); Daniel Shefchik (Milwaukee, Wisconsin) |
| ABSTRACT | Systems and methods for designing and fabricating three-dimensional objects with precisely computed material compositions for use in enhancing electromagnetic fields for magnetic resonance imaging (“MRI”) are provided. As examples, the fabricated object can be designed to reduce magnetic field inhomogeneities in the main magnetic field of an MRI system, or to reduce inhomogeneities in a transmit radio frequency (“RF”) field (i.e., a B1 field). As examples, the object can be a shim; a housing or other part of an RF coil; a medical device, such as a surgical implant; or component used in a medical device, such as a housing for an implantable medical device. |
| FILED | Wednesday, May 20, 2015 |
| APPL NO | 15/312844 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/055 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 50/00 (20141201) B33Y 50/02 (20141201) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/243 (20130101) G01R 33/246 (20130101) G01R 33/387 (20130101) G01R 33/5659 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11540769 | Prerau et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Michael J. Prerau (Watertown, Massachusetts); Patrick L. Purdon (Somerville, Massachusetts) |
| ABSTRACT | A system and method is provided for tracking sleep dynamics in a subject. In one aspect, a method includes acquiring physiological data using sensors positioned about the subject, and acquiring behavioral data using input provided by the subject. The method also includes generating a statistical model of wakefulness by combining information obtained from the acquired physiological data and behavior data, and estimating a probability indicative of a degree to which the subject is awake at each point in time during sleep onset using the statistical model. The method further includes generating a report indicative of sleep onset in the subject. |
| FILED | Tuesday, April 28, 2015 |
| APPL NO | 15/305596 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/113 (20130101) A61B 5/08 (20130101) A61B 5/11 (20130101) A61B 5/021 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/374 (20210101) A61B 5/389 (20210101) A61B 5/398 (20210101) A61B 5/0533 (20130101) A61B 5/681 (20130101) A61B 5/0816 (20130101) A61B 5/1118 (20130101) A61B 5/02055 (20130101) A61B 5/4812 (20130101) Original (OR) Class A61B 5/4848 (20130101) A61B 5/6825 (20130101) A61B 5/6898 (20130101) A61B 5/7246 (20130101) A61B 5/7264 (20130101) A61B 5/14542 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00536 (20130101) Image or Video Recognition or Understanding G06V 40/20 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541004 | Tizabi et al. |
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| FUNDED BY |
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| APPLICANT(S) | HOWARD UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | HOWARD UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | Yousef Tizabi (Silver Spring, Maryland); Robert L. Copeland (Washington, District of Columbia) |
| ABSTRACT | A method for treating or mitigating Parkinson's disease (PD) symptoms or progression, including administering an effective amount of nicotine to a subject in need thereof, via inhalation using a nicotine inhaler or via nasal spray using a nicotine nasal spray. Significant dose-dependent improvement of all symptoms by nicotine inhaler or nicotine nasal spray is expected. A novel treatment in PD is thus provided. |
| FILED | Wednesday, June 10, 2020 |
| APPL NO | 16/897780 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 9/0075 (20130101) Original (OR) Class A61K 31/465 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541015 | Traverso et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Carlo Giovanni Traverso (Newton, Massachusetts); Alex G. Abramson (St. Louis, Missouri); Ester Caffarel Salvador (Cambridge, Massachusetts); Niclas Roxhed (Cambridge, Massachusetts); Minsoo Khang (Boston, Massachusetts); Taylor Bensel (Walpole, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component is associated with a self-actuating component. For example, the self-righting article may comprise a self-actuating component configured, upon exposure to a fluid, to release the tissue interfacing component from the self-righting article. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent (e.g., for delivery to a location internal to a subject). |
| FILED | Thursday, May 17, 2018 |
| APPL NO | 16/614229 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/06 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/4808 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/158 (20130101) A61M 5/1454 (20130101) A61M 5/14276 (20130101) A61M 37/0015 (20130101) A61M 37/0069 (20130101) A61M 2005/1581 (20130101) A61M 2005/1585 (20130101) A61M 2037/0023 (20130101) A61M 2205/21 (20130101) A61M 2205/0238 (20130101) A61M 2210/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541044 | McCormick et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Leidos Biomedical Research, Inc. (Frederick, Maryland) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Leidos Biomedical Research, Inc. (Fredrick, Maryland) |
| INVENTOR(S) | Frank McCormick (San Francisco, California); Adam R. Renslo (Oakland, California); David Turner (Frederick, Maryland); Stephan Gysin (Basel, Switzerland); Anna E. Maciag (Frederick, Maryland); Oleg Chertov (Frederick, Maryland) |
| ABSTRACT | Provided herein, inter alia, are methods and compounds for inhibiting K-Ras and for treating cancer. |
| FILED | Wednesday, October 28, 2020 |
| APPL NO | 17/082125 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/445 (20130101) Original (OR) Class A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 207/16 (20130101) C07D 211/28 (20130101) C07D 211/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541047 | Govindan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Immunomedics, Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Immunomedics, Inc. (Foster City, California) |
| INVENTOR(S) | Serengulam V. Govindan (Summit, New Jersey); David M. Goldenberg (Mendham, New Jersey) |
| ABSTRACT | The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to EGP-1 (TROP-2), CEACAM5, CEACAM6, CD74, CD19, CD20, CD22, CSAp, HLA-DR, AFP or MUC5ac and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 24 mg/kg, preferably 4, 6, 8, 9, 10, 12, 16 or 18 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. |
| FILED | Friday, May 01, 2020 |
| APPL NO | 16/864245 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/481 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/454 (20130101) A61K 31/513 (20130101) A61K 31/675 (20130101) A61K 31/713 (20130101) A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) A61K 47/6851 (20170801) A61K 47/6853 (20170801) A61K 2039/55 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/545 (20130101) Peptides C07K 16/30 (20130101) C07K 16/32 (20130101) C07K 16/303 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2887 (20130101) C07K 16/3007 (20130101) C07K 16/3015 (20130101) C07K 16/3023 (20130101) C07K 16/3061 (20130101) C07K 16/3092 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541062 | Sun et al. |
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| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Zijie Sun (Duarte, California); David Horne (Duarte, California); Junfeng Li (Duarte, California); John E. Shively (Duarte, California); Jun Xie (Duarte, California) |
| ABSTRACT | Provided herein are methods for treating metastatic prostate cancer using anti-androgen compounds and radionuclide-labeled androgens. |
| FILED | Tuesday, February 11, 2020 |
| APPL NO | 16/787589 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) Original (OR) Class A61K 51/0493 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541065 | Poddar et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico); Ranjana Poddar (Albuquerque, New Mexico); Surojit Paul (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ranjana Poddar (Albuquerque, New Mexico); Surojit Paul (Albuquerque, New Mexico) |
| ABSTRACT | A method for treating a hyperhomocysteinemic subject having cerebral ischemic stroke generally includes administering to the hyperhomocysteinemic subject, following cerebral stroke, a composition that includes an inhibitor or an antagonist of a GluN2A-containing N-methyl-D-aspartate receptor (NMDAR) in an amount effective to ameliorate at least one symptom or clinical sign of cerebral stroke. |
| FILED | Monday, July 08, 2019 |
| APPL NO | 16/973825 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/415 (20130101) A61K 31/497 (20130101) A61K 31/675 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541072 | Lei |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| INVENTOR(S) | Hetian Lei (West Roxbury, Massachusetts) |
| ABSTRACT | Editing of VEGFR2 abrogated angiogenesis in two mouse models of oxygen-induced retinopathy (OIR) and laser-induced choroid neovascularization (CNV). Provided are compositions, e.g., Adeno-Associated Virus (AAV) Vectors comprising sequences encoding CRISPR/Cas9 proteins and guide RNA, and methods of use thereof for editing of Vascular endothelial growth factor receptor 2 (VEGFR2) gene to treat ocular disease associated with pathological angiogenesis, e.g., neovascular age-related macular degeneration (AMD), proliferative diabetic retinopathy (PDR) and retinopathy of prematurity (ROP). |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/621889 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/7105 (20130101) Original (OR) Class A61K 35/761 (20130101) A61K 38/465 (20130101) A61K 45/06 (20130101) A61K 48/005 (20130101) A61K 48/0075 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/907 (20130101) C12N 15/1138 (20130101) C12N 2320/32 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541073 | Hildeman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | David A. Hildeman (Cincinnati, Ohio); Andrew Herr (Cincinnati, Ohio); Suhas G. Kallapur (Cincinnati, Ohio); Jarek Meller (Cincinnati, Ohio); Alexander Thorman (Cincinnati, Ohio) |
| ABSTRACT | The disclosure provides methods of modulating an immune response by inhibiting BFL1, and related methods for treating and preventing diseases and disorders characterized by inflammation, especially neutrophil induced inflammation. |
| FILED | Monday, January 14, 2019 |
| APPL NO | 15/733346 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/655 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 31/7105 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541074 | Machielse et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mandos LLC (West Hollywood, California) |
| ASSIGNEE(S) | Mandos LLC (West Hollywood, California) |
| INVENTOR(S) | Bernardus Nicolaas Machielse (North Potomac, Maryland); Allan Darling (North Potomac, Maryland) |
| ABSTRACT | This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/745481 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/724 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541078 | Marban et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Eduardo Marban (Santa Monica, California); Lilian Grigorian (Los Angeles, California) |
| ABSTRACT | Described herein are compositions and methods related to use of cardiosphere-derived cells and their extracellular vesicles, such as exosomes and microvesicles, for achieving anti-aging and rejuvenation. This includes discoveries for effects on heart structure, function, gene expression, and systemic parameters. For animal studies, intra-cardiac injections of neonatal rat CDCs was compared to in old and young rats including evaluation of blood, echocardiographic, haemodynamic and treadmill stress tests. For in vitro studies, human heart progenitors from older donors, or cardiomyocytes from aged rats were exposed to human CDCs or cardiosphere derived cell (CDC) derived exosomes (CDC-XO) from pediatric donors. CDCs and CDC-XOs were capable of effectuating youthful patterns of gene expression in the hearts of old, along with a variant of physiological and function benefits, including elongation of telomere length. Together, these results indicate capacity of CDCs and CDC-XO to ward off the effects of aging through rejuvenation. |
| FILED | Tuesday, September 19, 2017 |
| APPL NO | 16/333581 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/127 (20130101) A61K 35/34 (20130101) Original (OR) Class A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 9/04 (20180101) A61P 17/14 (20180101) A61P 19/02 (20180101) A61P 25/28 (20180101) A61P 39/00 (20180101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 9/1276 (20130101) C12N 9/2471 (20130101) Enzymes C12Y 207/07049 (20130101) C12Y 302/01023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541087 | Deng et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Liang Deng (New York, New York); Stewart Shuman (New York, New York); Jedd Wolchok (New York, New York); Taha Merghoub (New York, New York); Weiyi Wang (New York, New York); Peihong Dai (New York, New York); Ning Yang (New York, New York) |
| ABSTRACT | The present invention relates generally to the fields of oncology, virology and immunotherapy. More particularly, it concerns the use of poxviruses, specifically the replication competent attenuated vaccinia virus with deletion of thymidine kinase (VC-TK−) with and without the expression of human Flt3L or GM-CSF as oncolytic and immunotherapy. The foregoing poxviruses can also be used in combination with immune checkpoint blocking agents. The foregoing poxviruses can also be inactivated via Heat or UV-treatment and the inactivated virus can be used as immunotherapy either alone or in combination with immune checkpoint blocking agents. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988137 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) A61K 35/768 (20130101) Original (OR) Class A61K 39/3955 (20130101) A61K 48/00 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/521 (20130101) C07K 14/535 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/24121 (20130101) C12N 2710/24132 (20130101) C12N 2710/24133 (20130101) C12N 2710/24143 (20130101) C12N 2710/24161 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541101 | Barker et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia); Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Thomas H. Barker (Crozet, Virginia); Leandro Moretti (Charlottesville, Virginia); Dwight M. Chambers (Atlanta, Georgia) |
| ABSTRACT | Methods and compositions for modulating transforming growth factor-beta (TGFβ) biological activity in a vertebrate subject in need thereof. The methods involve administering to the vertebrate subject an effective amount of a substance capable of modulating activity of LEMD3 in the vertebrate subject to thereby modulate TGFβ biological activity in the vertebrate subject. |
| FILED | Wednesday, October 09, 2019 |
| APPL NO | 16/597712 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 48/0066 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541105 | Sauer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of new York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | Karin Sauer (Binghamton, New York); Amber L. Doiron (Vestal, New York) |
| ABSTRACT | A method of treating a biofilm on a surface, comprising: providing a surface having a biofilm; and administering to the surface a treatment that reduces a concentration of pyruvate of the biofilm, comprising pyruvate produced by at least a portion the biofilm, under conditions effective reducing maintenance of the biofilm on the surface. A composition, comprising purified enzyme, within a particle, effective for reducing pyruvate concentration in an aqueous suspension of the composition. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 16/428560 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/18 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/44 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/00 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/38 (20210501) C12R 2001/44 (20210501) C12R 2001/185 (20210501) Enzymes C12Y 102/04001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541108 | Ganta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | Roman R. Ganta (Manhattan, Kansas); Ying Wang (Manhattan, Kansas) |
| ABSTRACT | Targeted disruption of a specific gene and its subsequent restoration in obligate intracellular bacteria remains extremely challenging due to their absolute requirement for residence inside a host cell to replicate. Here, targeted allelic exchange mutations were created to inactivate two genes and then to restore one of the two genes of a rickettsial pathogen, Ehrlichia chaffeensis. These methods were then also successfully utilized in Ehrlichia canis and Anaplasma phagocyophilum. The resultant mutated pathogens are useful in immunogenic compositions for reducing the incidence of or severity of infection with ricksettsial pathogens. |
| FILED | Monday, April 30, 2018 |
| APPL NO | 16/609097 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/118 (20130101) A61K 39/0233 (20130101) Original (OR) Class A61K 2039/522 (20130101) A61K 2039/552 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541110 | Pfeifer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| INVENTOR(S) | Blaine Pfeifer (Buffalo, New York); Charles Jones (North Tonawanda, New York) |
| ABSTRACT | Provided are vaccine compositions and methods against Streptococcus pneumoniae. The composition comprises liposomes which have polysaccharides from one or more serotypes and have proteins non-covalently attached to the surface and exposed to the exterior. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/755537 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 39/092 (20130101) Original (OR) Class A61K 2039/622 (20130101) A61K 2039/625 (20130101) A61K 2039/6037 (20130101) A61K 2039/6068 (20130101) A61K 2039/55555 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541114 | Diamond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Don Diamond (Glendora, California); Zhongde Wang (Mount Pleasant, South Carolina) |
| ABSTRACT | A vaccine comprising an immunologically effective amount of recombinant modified vaccinia Ankara (rMVA) virus which is genetically stable after serial passage and produced by a) constructing a transfer plasmid vector comprising a modified H5 (mH5) promoter operably linked to a DNA sequence encoding a heterologous foreign protein antigen, wherein the expression of said DNA sequence is under the control of the mH5 promoter; b) generating rMVA virus by transfecting one or more plasmid vectors obtained from step a) into wild type MVA virus; c) identifying rMVA virus expressing one or more heterologous foreign protein antigens using one or more selection methods for serial passage; d) conducting serial passage; e) expanding an rMVA virus strain identified by step d); and f) purifying the rMVA viruses from step e) to form the vaccine. One embodiment is directed to a fusion cytomegalovirus (CMV) protein antigen comprising a nucleotide sequence encoding two or more antigenic portions of Immediate-Early Gene-1 or Immediate-Early Gene-2 (IEfusion), wherein the antigenic portions elicit an immune response when expressed by a vaccine. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 16/834359 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/245 (20130101) A61K 39/285 (20130101) Original (OR) Class A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/16134 (20130101) C12N 2710/16151 (20130101) C12N 2710/24143 (20130101) C12N 2830/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541121 | Herrmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Andreas Herrmann (Del Mar, California); Hua Yu (Glendora, California); Toshikage Nagao (Duarte, California) |
| ABSTRACT | Provided herein are, inter alia, nucleic acid-peptide conjugates including a non-cell penetrating protein attached at its C-terminus to a phosphorothioate nucleic acid. Attachment of the phosphorothioate nucleic acid to the non-cell penetrating protein conveys stability to and allows for efficient intracellular delivery of the non-cell penetrating peptide. The nucleic acid-peptide conjugates provided herein including embodiments thereof are useful, inter alia, for the treatment of cancer, inflammatory disease, pain, and viral infection. |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/630343 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 38/1774 (20130101) A61K 47/549 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) A61P 31/18 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541125 | Maynard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Heather D. Maynard (Los Angeles, California); Natalie Boehnke (Los Angeles, California); Samantha J. Paluck (Los Angeles, California) |
| ABSTRACT | Non-crushable pill formulations and methods of using the formulations are disclosed. A non-crushable pill formulation for preventing unintended use of a drug, comprising a polymer, the polymer forming a polymer backbone of the complex; cross-linkers, the cross-linkers connecting the polymer backbone through covalently bonding to form at least one inner cavity within the complex; and the drug, the drug being trapped either covalently or non-covalently in the at least one inner cavity within the complex, wherein the drug is protected from releasing outside of the complex. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 16/469786 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/2036 (20130101) A61K 31/485 (20130101) A61K 47/59 (20170801) A61K 47/60 (20170801) A61K 47/65 (20170801) Original (OR) Class A61K 47/6943 (20170801) Enzymes C12Y 304/11 (20130101) C12Y 304/21004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541149 | Breuer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
| ASSIGNEE(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
| INVENTOR(S) | Christopher Breuer (New Albany, Ohio); Cameron Best (Blacklick, Ohio); Robert Strouse (Columbus, Ohio); Narutoshi Hibino (Towson, Maryland); Yong Ung-Lee (Columbus, Ohio) |
| ABSTRACT | It has been established that optimizing cell seeding onto tissue engineering vascular grafts (TEVG) is associated with reduced inflammatory responses and reduced post-operative stenosis of TEVG. Cell seeding increased TEVG patency in a dose dependent manner, and TEVG patency improved when more cells were seeded, however duration of incubation time showed minimal effect on TEVG patency. Methods of engineering patient specific TEVG including optimal numbers of cells to maintain graft patency and reduce post-operative stenosis are provided. Closed, single-use customizable systems for seeding TEVG are also provided. Preferably the systems are custom-designed based on morphology of the patient specific graft, to enhance the efficacy of cell seeding. |
| FILED | Monday, December 12, 2016 |
| APPL NO | 15/781679 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/20 (20130101) A61L 27/24 (20130101) A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/507 (20130101) A61L 27/3834 (20130101) Original (OR) Class A61L 2300/41 (20130101) A61L 2300/414 (20130101) A61L 2300/416 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Compositions of Macromolecular Compounds C08L 67/04 (20130101) C08L 77/00 (20130101) C08L 85/02 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541251 | Flynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Ryan T. Flynn (Iowa City, Iowa); Yusung Kim (Iowa City, Iowa); Xiaodong Wu (Coralville, Iowa); Karolyn M. Hopfensperger (Iowa City, Iowa); Quentin E. Adams (Iowa City, Iowa) |
| ABSTRACT | Methods and systems are described for a rotating shield brachytherapy device. As disclosed herein, the rotating shield brachytherapy (RSBT) apparatus may comprise a radiation source, a drive assembly, a catheter, and an applicator. The applicator can have an outer surface and opposed proximal and distal end portions and a longitudinal axis extending along a length of the catheter. The distal end portion of the catheter can comprise one or more radiation shields and is configured to receive the radiation source. The drive assembly can be configured to engage the proximal end portion of the catheter to selectively rotate the catheter about the longitudinal axis. |
| FILED | Wednesday, September 25, 2019 |
| APPL NO | 17/277506 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1002 (20130101) Original (OR) Class A61N 2005/1005 (20130101) A61N 2005/1094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541559 | Lujan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOISE STATE UNIVERSITY (Boise, Idaho) |
| ASSIGNEE(S) | Boise State University (Boise, Idaho) |
| INVENTOR(S) | Trevor Lujan (Boise, Idaho); Sean Nelson (Meridian, Idaho); Madison Wale (Boise, Idaho); Danielle Siegel (Boise, Idaho); Jaremy Creechley (Laramie, Wyoming) |
| ABSTRACT | A system may include a blade die, a first clamping caul positioned on a first side of the blade die, and a second clamping caul positioned on a second side of the blade die. A molding surface of the blade die and a molding surface of the first clamping caul may be configured to bend a first interchangeable blade positioned therebetween into a first shape in response to a first compression force. A second molding surface of the blade die and a molding surface of the second clamping caul may be configured to bend a second interchangeable blade positioned therebetween into a second shape in response to a second compression force. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/234606 |
| ART UNIT | 3724 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2017/3225 (20130101) Hand-held Cutting Tools Not Otherwise Provided for B26B 5/006 (20130101) B26B 5/008 (20130101) Original (OR) Class B26B 9/02 (20130101) B26B 29/00 (20130101) Perforating; Punching; Cutting-out; Stamping-out; Severing by Means Other Than Cutting B26F 1/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542227 | Bergeson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Susan E. Bergeson (Lubbock, Texas); Peter Syapin (Camarillo, California); Ted W. Reid (Lubbock, Texas); Mayank Shashtri (Lubbock, Texas); Phat Tran (Lubbock, Texas) |
| ABSTRACT | A method of treating Alcohol Use Disorder (AUD), Substance Use Disorder (SUD), tobacco use, pain, or proinflammatory disorders comprising: providing a subject with an effective amount of a modified tetracycline or derivative thereof to ameliorate or eliminate the AUD, SUD, tobacco use, pain, or proinflammatory disorder, and wherein the modified tetracycline or derivative thereof has reduced binding to a microbial ribosome and has the formula wherein R1 is acetyl, R2 is OH or acetyl, R3 is acetyl, R4 is H or acetyl, and R5 is acetyl. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 16/973896 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4848 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/65 (20130101) Acyclic or Carbocyclic Compounds C07C 237/26 (20130101) Original (OR) Class C07C 2603/46 (20170501) Heterocyclic Compounds C07D 317/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542261 | Starczynowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Daniel T. Starczynowski (Cincinnati, Ohio); Craig J. Thomas (Gaithersburg, Maryland); Garrett Rhyasen (Burlington, Massachusetts); Katelyn Melgar (Cincinnati, Ohio); Morgan MacKenzie Walker (New haven, Connecticut); Jian-kang Jiang (Columbia, Maryland) |
| ABSTRACT | Some embodiments of the invention include inventive compounds (e.g., compounds of Formula (I)) and compositions (e.g., pharmaceutical compositions) which can be used for treating, for example, certain diseases. Some embodiments include methods of using the inventive compound (e.g., in compositions or in pharmaceutical compositions) for administering and treating (e.g., diseases such as head and neck squamous cell carcinoma (HNSCC), cancer, blood disorders, etc.). Additional embodiments provide synergistic combinations of a BCL2 inhibitor with an IRAK inhibiting compound, and methods of using same. |
| FILED | Friday, February 28, 2020 |
| APPL NO | 16/804518 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542282 | Mach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Robert H. Mach (Wallingford, Pennsylvania); Sean W. Reilly (Philadelphia, Pennsylvania); Mehran Makvandi (Philadelphia, Pennsylvania); Laura Puentes (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure provides compounds of Formula (I) or (II), pharmaceutically acceptable salt, isotopic variant, stereoisomer, or a mixture thereof. Also provided are pharmaceutical compositions comprising a compound, methods of treating a poly(ADP-ribose)polymerase-1-mediated disease or disorder in a subject, methods of detecting a poly(ADP-ribose)polymerase-1-mediated neurodegenerative disease or disorder, or methods of monitoring cancer treatment in a subject. In some embodiments, the poly(ADP-ribose)polymerase-1-mediated disease or disorder is a neurodegenerative disease or cancer. |
| FILED | Thursday, February 28, 2019 |
| APPL NO | 16/976515 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) C07B 2200/05 (20130101) Heterocyclic Compounds C07D 237/32 (20130101) C07D 403/10 (20130101) C07D 471/10 (20130101) C07D 487/10 (20130101) C07D 491/107 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/6896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542288 | Schiffer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Celia A. Schiffer (Shrewsbery, Massachusetts); Akbar Ali (Westborough, Massachusetts); Nese Kurt-Yilmaz (Shrewsbury, Massachusetts); Linah N. Rusere (Hendersonville, North Carolina); Gordon J. Lockbaum (Worcester, Massachusetts); Mina Henes (Boxborough, Massachusetts) |
| ABSTRACT | The present application provides compounds and methods of treating viral infections, including viral infections caused by HIV or HTLV. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/334454 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6561 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542291 | Ziegler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation, University Park (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Gregory Ray Ziegler (State College, Pennsylvania); Joshua David Lambert (State College, Pennsylvania); Emmanuel Hatzakis (Columbus, Ohio); Eugene P. Mazzola (Vienna, Virginia) |
| ABSTRACT | The present invention provides compounds isolated from avocado seeds for use as a natural colorant in edible materials. The compounds of the invention are useful for coloring edible materials red, orange, or yellow. The invention also provides compositions and methods for coloring edible materials to a desired color such as red, orange, or yellow. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 16/512445 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 59/82 (20130101) C07C 2603/30 (20170501) Heterocyclic Compounds C07D 305/10 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/24 (20130101) Original (OR) Class C07H 15/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542296 | Reddy |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| INVENTOR(S) | Doodipala Samba Reddy (Bryan, Texas) |
| ABSTRACT | Described herein is the chemical structure of neurosteroid derivative compounds, methods of synthesizing the derivatives, and their uses in treating disorders, including those of the central nervous system. These compounds are readily synthesized and have improved pharmaceutical properties, including water solubility, compared to known neurosteroids. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 17/049976 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) Steroids C07J 5/0015 (20130101) C07J 41/0088 (20130101) C07J 43/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542305 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Xiaojing Gao (Los Angeles, California); Michael B. Elowitz (Los Angeles, California) |
| ABSTRACT | Disclosed herein include methods, compositions, and kits suitable for use in detecting the activation level of a signal transducer. In some embodiments, there are provided synthetic protein circuits wherein recruitment of synthetic protein circuit components to an association location upon activation of a signal transducer generates an active effector protein. The effector protein can be configured to carry out a variety of functions when in an active state, such as, for example, inducing cell death. Methods of treating a disease or disorder characterized by aberrant signaling are provided in some embodiments. |
| FILED | Thursday, August 29, 2019 |
| APPL NO | 16/556063 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/001 (20130101) Original (OR) Class C07K 14/47 (20130101) C07K 2319/02 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/506 (20130101) Enzymes C12Y 304/22044 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542314 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Aimei Yang (Natick, Massachusetts); Demian Park (Cambridge, Massachusetts); Edward S. Boyden (Chestnut Hill, Massachusetts) |
| ABSTRACT | The invention, in some aspects relates to light-activated ion channel molecules and methods for their use to alter cell activity and function. Light-activated ion channel molecules of the invention can be administered to subjects, expressed in cells, and activated with light, to alter membrane potential in the cells, and can be used in methods for assaying compounds, treating diseases and conditions, compound screening and more. |
| FILED | Monday, September 10, 2018 |
| APPL NO | 16/126384 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/705 (20130101) Original (OR) Class C07K 14/721 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/79 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 33/5076 (20130101) G01N 33/6872 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542319 | Leighton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Crystal Bioscience Inc. (San Diego, California) |
| ASSIGNEE(S) | CRYSTAL BIOSCIENCE INC. (Emeryville, California) |
| INVENTOR(S) | Philip A. Leighton (San Francisco, California); William Don Harriman (Alameda, California); Robert Etches (Oakland, California) |
| ABSTRACT | A transgenic chicken comprising an inactivated heavy immunoglobulin gene and/or inactivated light chain immunoglobulin gene is provided, as well as cells and targeting vectors for making the same. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875644 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2227/30 (20130101) Peptides C07K 16/00 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/24 (20130101) C07K 2317/51 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542328 | Frank et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Markus H. Frank (Cambridge, Massachusetts); Natasha Y. Frank (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates in part to the discovery of genes that are deregulated in cancer stem cells (e.g., melanoma stem cells). In some aspects, methods for treating individuals having melanoma are provided; the methods involve modulating (e.g., inducing, inhibiting, etc.) the activity of the cancer stem cell associated genes. In other aspects, cell surface genes that are upregulated in melanoma stem cells are targeted for the selective isolation, detection, and killing of cancer stem cells in melanoma. Other aspects of the invention relate to reagents, arrays, compositions, and kits that are useful for diagnosing and treating melanoma. |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/435929 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 51/1096 (20130101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/51 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/122 (20130101) C12N 2310/3513 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) G01N 33/57419 (20130101) G01N 33/57434 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542472 | Edge |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| INVENTOR(S) | Albert Edge (Brookline, Massachusetts) |
| ABSTRACT | Methods for generating cells of the inner ear, e.g., hair cells and supporting cells, from stem cells, e.g., mesenchymal stem cells, are provided, as well as compositions including the inner ear cells. Methods for the therapeutic use of the inner ear cells for the treatment of hearing loss are also described. |
| FILED | Friday, November 08, 2019 |
| APPL NO | 16/678990 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) C12N 5/0627 (20130101) Original (OR) Class C12N 2501/42 (20130101) C12N 2506/1353 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542475 | Woodruff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urban, Illinois); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Teresa K. Woodruff (Chicago, Illinois); Ji-Yong Julie Kim (Elmhurst, Illinois); Joanna E. Burdette (Chicago, Illinois); Spiro Getsios (Chicago, Illinois); Sevim Yildiz Arslan (Chicago, Illinois); Shuo Xiao (Chicago, Illinois); Jie Zhu (Chicago, Illinois) |
| ABSTRACT | The present invention relates generally to a three-dimensional cell and tissue culture system for the female reproductive tract. In particular provided herein the system includes individual female reproductive cultures in a dynamic microfluidic setting or integrated using a microfluidic microphysiologic system. In some embodiments, the present invention provides ex-vivo female reproductive tract integration in a three dimensional (3D) microphysiologic system. |
| FILED | Monday, October 21, 2019 |
| APPL NO | 16/659520 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0682 (20130101) Original (OR) Class C12N 5/0697 (20130101) C12N 2501/11 (20130101) C12N 2501/31 (20130101) C12N 2502/243 (20130101) C12N 2513/00 (20130101) C12N 2533/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542478 | Hewitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Curtis Hewitt (Austin, Texas); Richard Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | This invention relates to modified parvovirus inverted terminal repeats (ITRs) that do not functionally interact with wild-type large Rep proteins, synthetic Rep proteins that functionally interact with the modified ITRs, and methods of using the same for delivery of nucleic acids to a cell or a subject. The modifications provide a novel Rep-ITR interaction that limits vector mobilization, increasing the safety of viral vectors. |
| FILED | Thursday, November 19, 2020 |
| APPL NO | 16/953109 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/8645 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14162 (20130101) C12N 2750/14322 (20130101) C12N 2750/14352 (20130101) C12N 2820/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542486 | Georgiou et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | George Georgiou (Austin, Texas); Everett Stone (Austin, Texas); John Blazeck (Austin, Texas) |
| ABSTRACT | Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids. |
| FILED | Thursday, March 02, 2017 |
| APPL NO | 16/081492 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/46 (20130101) A61K 39/3955 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Original (OR) Class C12N 9/96 (20130101) Enzymes C12Y 307/01003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542493 | Orkin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Stuart H. Orkin (Brookline, Massachusetts); Daniel E. Bauer (Cambridge, Massachusetts); Jian Xu (Plano, Texas) |
| ABSTRACT | Provided herein are methods and compositions for increasing fetal hemoglobin levels in a cell by disrupting BCL11A expression at the genomic level. Also provided herein are methods and compositions relating to the treatment of hemoglobinopathies by reinduction of fetal hemoglobin levels. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 16/573389 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 38/465 (20130101) Peptides C07K 14/805 (20130101) C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/01 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542500 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Xiaolu Yang (Wynnewood, Pennsylvania); Lili Guo (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for promoting the degradation of misfolded proteins and protein aggregates. The compositions and methods may be used to treat a disorder associated with misfolded proteins or protein aggregates. In certain instances, the compositions and methods relate to modulators of one or more TRIM proteins or one or more STUbLs. |
| FILED | Friday, May 27, 2016 |
| APPL NO | 15/577915 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/12 (20180101) A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2710/10043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) G01N 33/6896 (20130101) G01N 2800/2814 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542509 | Maianti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Juan Pablo Maianti (Revere, Massachusetts); David R. Liu (Lexington, Massachusetts); Luke W. Koblan (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are systems, compositions, and methods for the incorporation of unnatural amino acids into proteins via nonsense suppression or rare codon suppression. Nonsense codons and rare codons may be introduced into the coding sequence of a protein of interest using a CRISPR/Cas9-based nucleobase editor described herein. The nucleobase editors are able to be programmed by guide nucleotide sequences to edit the target codons in the coding sequence of the protein of interest. Also provided are application enabled by the technology described herein. |
| FILED | Thursday, August 24, 2017 |
| APPL NO | 16/327744 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/78 (20130101) C12N 15/67 (20130101) Original (OR) Class C12N 15/102 (20130101) Enzymes C12Y 305/04001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542527 | He |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| INVENTOR(S) | Biao He (Bogart, Georgia) |
| ABSTRACT | The present invention provides safe, stable, efficacious, and cost-effective vaccines based on viral expression vectors that include a parainfluenza virus 5 (PIV5) genome including a heterologous nucleotide sequence expressing a heterologous polypeptide. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/989038 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/04 (20130101) A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 39/155 (20130101) A61K 39/205 (20130101) A61K 2039/53 (20130101) A61K 2039/552 (20130101) A61K 2039/585 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) A61P 31/12 (20180101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2760/16134 (20130101) C12N 2760/16171 (20130101) C12N 2760/18021 (20130101) C12N 2760/18034 (20130101) C12N 2760/18721 (20130101) C12N 2760/18732 (20130101) C12N 2760/18743 (20130101) C12N 2760/18771 (20130101) C12N 2760/20134 (20130101) C12N 2760/20171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542545 | Ismagilov et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); Talis Biomedical Corporation (Redwood City, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); Talis Biomedical Corporation (Redwood City, California) |
| INVENTOR(S) | Rustem F. Ismagilov (Altadena, California); Eugenia Khorosheva (South Pasadena, California); Travis S. Schlappi (Pasadena, California); Matthew S. Curtis (Pasadena, California); Nathan G. Schoepp (Pasadena, California); Hedia Maamar (San Jose, California); Feng Shen (San Jose, California); Erik B. Jue (Pasadena, California) |
| ABSTRACT | Disclosed herein are methods and devices for rapid assessment of whether a microorganism present in a sample is susceptible or resistant to a treatment. |
| FILED | Thursday, November 05, 2015 |
| APPL NO | 15/524449 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 7/00 (20130101) B01L 2300/0861 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) C12Q 1/686 (20130101) C12Q 1/689 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6851 (20130101) Original (OR) Class C12Q 2537/165 (20130101) C12Q 2545/114 (20130101) C12Q 2565/629 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542554 | Daugharthy et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Evan R. Daugharthy (Cambridge, Massachusetts); Richard C. Terry (Carlisle, Massachusetts); Je-Hyuk Lee (Allston, Massachusetts); George M. Church (Brookline, Massachusetts); Benjamin W. Pruitt (Cambridge, Massachusetts) |
| ABSTRACT | Methods of volumetric imaging of a three-dimensional matrix of nucleic acids within a cell is provided. An automated apparatus for sequencing and volumetric imaging of a three-dimensional matrix of nucleic acids is provided. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/395534 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2543/101 (20130101) C12Q 2543/101 (20130101) C12Q 2563/159 (20130101) C12Q 2563/159 (20130101) C12Q 2565/601 (20130101) C12Q 2565/601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542555 | Feldman et al. |
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| FUNDED BY |
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| APPLICANT(S) | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Arthur M. Feldman (Wynnewood, Pennsylvania); Douglas G. Tilley (Bryn Mawr, Pennsylvania); Weizhong Zhu (Cockeysville, Maryland); Kamel Khalili (Bala Cynwyd, Pennsylvania); Walter J. Koch (Broomall, Pennsylvania) |
| ABSTRACT | Compositions are directed to BCL2-associated athanogene 3 (BAG3) molecules and agents which modulate expression of BAG3 molecules. Pharmaceutical composition for administration to patients, for example, patients with heart failure, comprise one or more BAG3 molecules or agents which modulate expression of BAG3. Methods of treatment and identifying candidate therapeutic agents are also provided. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 15/929784 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) G01N 33/6893 (20130101) G01N 2500/04 (20130101) G01N 2500/10 (20130101) G01N 2800/50 (20130101) G01N 2800/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542635 | Schulz et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | UNIVERSITY OF CINCINNATI (Cincinnati, Ohio) |
| INVENTOR(S) | Mark J. Schulz (West Chester, Ohio); Sathya Kanakaraj (Cincinnati, Ohio); David Mast (Cincinnati, Ohio); Vesselin Shanov (Cincinnati, Ohio); Devika Chauhan (Cincinnati, Ohio); Guangfeng Hou (Perrysburg, Ohio); Vianessa Ng (Miami, Florida); Chenhao Xu (Lakeside Park, Kentucky); Rui Daniel Chen (Cincinnati, Ohio); Ashley Kubley (Cincinnati, Ohio); Xiaoda Hou (Fruitland Park, Florida); Richard Kleismit (Cincinnati, Ohio); Zhangzhang Yin (Monroeville, Pennsylvania) |
| ABSTRACT | Carbon nanotube (CNT) fiber and sheets formed by a specialized gas assembly pyrolytic reactor method that permits gas phase integration of nano and micro particles (NMPs) are processed into yarn and fabric used in the manufacture of personal protective clothing and equipment that can be tailored via selection of NMPs for a wide variety of functionality depending on target application. The CNT-NMP hybrid fabrics may be designed to exhibit enhanced electrical and thermal conductivity, moisture wicking, air filtering, and environmental sensing properties. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/629714 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/127 (20130101) Original (OR) Class Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/40 (20130101) D02G 3/047 (20130101) D02G 3/441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543037 | Payne et al. |
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| FUNDED BY |
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| APPLICANT(S) | SFC Fluidics, Inc. (Fayetteville, Arkansas) |
| ASSIGNEE(S) | SFC Fluidics, Inc. (Fayetteville, Arkansas) |
| INVENTOR(S) | Forrest W. Payne (Fayetteville, Arkansas); Bradley Ledden (Fayetteville, Arkansas); Gil Kan (Alpharetta, Georgia); Greg Lamps (Smyrna, Georgia) |
| ABSTRACT | A dual latching microvalve is capable of a metastable state, wherein a one or more complete flow paths are open, before switching to another state that allows only an inlet or outlet valve to be open at any time on any fluid path. One valve mechanism uses a cam to alternately open and close two valves, with an external force applying pressure to move one valve arm onto a resting position on the cam, thereby opening the closed valve and provided an uninterrupted flow path through the dual latching microvalve. The metastable state provides, for example, a means to prime the pump before operation, such as pumping of insulin into a patient. When released from the metastable state, the dual latching microvalve operates in a fashion whereby opening of both valves simultaneously is prevented, thereby protecting the patient from injury. |
| FILED | Thursday, August 29, 2019 |
| APPL NO | 17/271247 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 7/045 (20130101) F16K 7/065 (20130101) Original (OR) Class F16K 11/027 (20130101) F16K 99/0026 (20130101) F16K 99/0038 (20130101) F16K 2099/0069 (20130101) F16K 2099/0071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543339 | Vacca et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kinetic River Corp. (Mountain View, California) |
| ASSIGNEE(S) | KINETIC RIVER CORP. (Mountain View, California) |
| INVENTOR(S) | Giacomo Vacca (Campbell, California); Ralph Jimenez (Boulder, Colorado) |
| ABSTRACT | Described herein are apparatuses for analyzing an optical signal decay. In some embodiments, an apparatus includes: a source of a beam of pulsed optical energy; a sample holder configured to expose a sample to the beam; a detector comprising a number of spectral detection channels configured to convert the optical signals into respective electrical signals; and a signal processing module configured to perform a method. In some embodiments, the method includes: receiving the electrical signals from the detector; mathematically combining individual decay curves in the electrical signals into a decay supercurve, the supercurve comprising a number of components, each component having a time constant and a relative contribution to the supercurve; and numerically fitting a model to the supercurve. |
| FILED | Wednesday, May 05, 2021 |
| APPL NO | 17/308941 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/14 (20130101) Original (OR) Class G01N 15/147 (20130101) G01N 15/1429 (20130101) G01N 15/1434 (20130101) G01N 15/1436 (20130101) G01N 2015/144 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2015/1438 (20130101) G01N 2015/1477 (20130101) G01N 2015/1488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543371 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Yihua (Bruce) Yu (Ellicott City, Maryland); Marc B. Taraban (North Potomac, Maryland) |
| ABSTRACT | A method of using the transverse relaxation rate (R2) of solvent NMR signal to detect filling errors of an alum-containing product in real-time in-line during manufacturing, for example during a fill-finish unit operation. This technique can be used for quality control in vaccine manufacturing to ensure the delivery of the correct concentration of alum-containing product to the product container such as a vial or pre-filled syringe. |
| FILED | Wednesday, September 23, 2020 |
| APPL NO | 17/030088 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/084 (20130101) Original (OR) Class G01N 24/085 (20130101) G01N 33/15 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543411 | Bremer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Prelude Corporation (Laguna Hills, California) |
| ASSIGNEE(S) | Prelude Corporation (Laguna Hills, California) |
| INVENTOR(S) | Troy M. Bremer (Irvine, California); Steven Paul Linke (Carlsbad, California) |
| ABSTRACT | The present technology generally relates to methods and compositions relevant to the prediction that a subject with and/or after treatment for DCIS will experience a subsequent ipsilateral breast event that is a DCIS recurrence, an invasive breast cancer, both a DCIS recurrence and invasive cancer, or neither. The technology can assist one with how to treat such subjects. |
| FILED | Friday, December 04, 2015 |
| APPL NO | 15/529966 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) Original (OR) Class G01N 2333/723 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543429 | Ozturk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Morgan State University (Baltimore, Maryland) |
| ASSIGNEE(S) | Morgan State University (Baltimore, Maryland) |
| INVENTOR(S) | Birol Ozturk (Parkville, Maryland); Alperen Guver (Baltimore, Maryland); Peker Milas (Baltimore, Maryland) |
| ABSTRACT | Disclosed is a method for preparing nanoscale electrodes comprised of electrochemically grown noble metal nanowires, and use of the same for the detection of extremely small concentrations of molecules. Such nanoscale electrodes provide target molecule release information from submicron areas on the cell surface, significantly increasing the spatial resolution of the target molecule mapping of a cell surface to enable localization of target molecules on the cell surface, which can be critical for the detection of certain cells with different properties in a given group of cells, such as circulating tumor cells. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/857821 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5438 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/60 (20130101) Original (OR) Class G01Q 70/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543465 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Scott Green (Davison, Michigan); Yogesh B. Gianchandani (Ann Arbor, Michigan); Richard Kwon (Ann Arbor, Michigan); Grace Elta (Ann Arbor, Michigan); Jiqing Jiang (Sunnyvale, California); Ramprasad Nambisan (Ann Arbor, Michigan) |
| ABSTRACT | Encapsulation packages for stent-deployable monitoring devices formed of resonator sensors and allowing for magnetic biasing elements that exhibit a targeted impact on the mechanical characteristics of a stent are provided. Encapsulation packages are formed of different types and include a longitudinal shield and curved end on profile for aligning the shield within the deployable stent, the shield having perforations such that a resonator can be positioned adjacent the perforations for allowing particulate within the stent to collect and be measured by the resonator during deployment. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 16/841323 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/6862 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/82 (20130101) A61F 2002/825 (20130101) A61F 2250/0058 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2202/0403 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/18 (20130101) G01R 33/0047 (20130101) Original (OR) Class G01R 33/3692 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543475 | Woo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Myung Kyun Woo (Minneapolis, Minnesota); Gregor Adriany (Minneapolis, Minnesota); Kamil Ugurbil (Minneapolis, Minnesota); Russell L. Lagore (Minneapolis, Minnesota); Lance DelaBarre (Minneapolis, Minnesota); Jerahmie Radder (Minneapolis, Minnesota) |
| ABSTRACT | An antenna apparatus for a radio frequency (RF) coil to transmit signals to and to receive signal from a subject in a magnetic resonance imaging (MRI) system includes a distal surface facing away from the subject, a proximal surface facing towards the subject, a high permittivity material (HPM) having a shape, and an antenna coupled to the HPM and positioned on the proximal surface such that the antenna is positioned between the HPM and the subject. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 16/859771 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/288 (20130101) Original (OR) Class G01R 33/341 (20130101) Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 7/00 (20130101) H01Q 21/29 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543481 | Murphy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Matthew C. Murphy (Rochester, Minnesota); Richard L. Ehman (Rochester, Minnesota); Kevin J. Glaser (Rochester, Minnesota); Joshua D. Trzasko (Rochester, Minnesota); Armando Manduca (Rochester, Minnesota); John Huston, III (Rochester, Minnesota); Jonathan M. Scott (Rochester, Minnesota); Arvin Forghanian-Arani (Rochester, Minnesota) |
| ABSTRACT | Magnetic resonance elastography (“MRE”), or other imaging-based elastography techniques, generate estimates of the mechanical properties, such as stiffness and damping ratio, of tissues in a subject. A machine learning approach, such as an artificial neural network, is implemented to perform an inversion of displacement data in order to generate the estimates of the mechanical properties. |
| FILED | Monday, November 19, 2018 |
| APPL NO | 16/764838 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/7267 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/307 (20130101) G01R 33/5608 (20130101) G01R 33/56358 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543483 | Dosenbach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Nico Dosenbach (St. Louis, Missouri); Jonathan Koller (St. Louis, Missouri); Andrew Van (St. Louis, Missouri); Abraham Snyder (St. Louis, Missouri); Amy Mirro (St. Louis, Missouri); Damien Fair (Portland, Oregon); Eric Earl (Portland, Oregon); Rachel Klein (Portland, Oregon); Oscar Miranda Dominguez (Tigard, Oregon); Anders Perrone (Portland, Oregon) |
| ABSTRACT | Methods, computer-readable storage devices, and systems are described for reducing movement of a patient undergoing a magnetic resonance imaging (MRI) scan by aligning MRI data, the method implemented on a Framewise Integrated Real-time MRI Monitoring (“FIRMM”) computing device including at least one processor in communication with at least one memory device. Aspects of the method comprise receiving a data frame from the MRI system, aligning the received data frame to a preceding data frame, calculating motion of a body part between the received data frame and the preceding data frame, calculating total frame displacement, and excluding data frames with a cutoff above a pre-identified threshold of the total frame displacement. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/451539 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0041 (20130101) G01R 33/4831 (20130101) G01R 33/5608 (20130101) G01R 33/56509 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543638 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ye Hu (Scottsdale, Arizona); Dali Sun (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Ye Hu (Scottsdale, Arizona); Dali Sun (Tempe, Arizona) |
| ABSTRACT | A mobile phone-based dark field microscope (MDFM) apparatus suitable for quantifying nanoparticle signals is provided. The MDFM apparatus includes an electrically operated light source, a dark-field condenser, a slide housing configured to receive an analytical slide, and an adapter housing configured to receive an objective lens and receive a portable electronic communication device. The slide housing positions the analytical slide between the objective lens and the dark-field condenser. The adapter housing registers the objective lens with a camera lens of the portable electronic communication device. A method for performing a biological quantitative study using the dark-field microscope apparatus is further provided. |
| FILED | Thursday, August 09, 2018 |
| APPL NO | 16/637733 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/51 (20130101) G01N 33/587 (20130101) G01N 2201/0221 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0008 (20130101) Original (OR) Class G02B 21/10 (20130101) G02B 21/025 (20130101) G02B 21/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544607 | Sun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Haoliang Sun (Madison, Wisconsin); Ronak R. Mehta (Madison, Wisconsin); Hao Zhou (Madison, Wisconsin); Vikas Singh (Madison, Wisconsin); Vivek Prabhakaran (Fitchburg, Wisconsin); Stirling C. Johnson (Fitchburg, Wisconsin) |
| ABSTRACT | A machine learning architecture employs two machine learning networks that are joined by a statistical model allowing the imposition of a predetermined statistical model family into a learning process in which the networks translate between and data types. For example, the statistical model may enforce a Gaussian conditional probability between the latent variables in the translation process. In one application, MRI images may be translated into PET images with reduced mode collapse, blurring, or other “averaging” type behaviors. |
| FILED | Monday, May 20, 2019 |
| APPL NO | 16/417192 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) G06N 3/0454 (20130101) G06N 7/005 (20130101) Original (OR) Class G06N 20/20 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545173 | Provost et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Emily Mower Provost (Ann Arbor, Michigan); Melvin McInnis (Ann Arbor, Michigan); John Henry Gideon (Howell, Michigan); Katherine Anne Matton (Ann Arbor, Michigan); Soheil Khorram (Richardson, Texas) |
| ABSTRACT | A method of predicting a mood state of a user may include recording an audio sample via a microphone of a mobile computing device of the user based on the occurrence of an event, extracting a set of acoustic features from the audio sample, generating one or more emotion values by analyzing the set of acoustic features using a trained machine learning model, and determining the mood state of the user, based on the one or more emotion values. In some embodiments, the audio sample may be ambient audio recorded periodically, and/or call data of the user recorded during clinical calls or personal calls. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 16/556858 |
| ART UNIT | 2652 — Videophones and Telephonic Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/63 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545236 | Saladi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Shyam M. Saladi (Pasadena, California); William M. Clemons (Pasadena, California) |
| ABSTRACT | Membrane protein expression can be predicted using statistical frameworks to provide an enhanced subset of sequences, out of an initial larger set of potentially expressing sequences, by using features derived from sequences and a model parameterized through a dataset of known expression levels. Also, membrane protein experimentation protocols can be designed using the statistical frameworks in concert known outcomes to identify which laboratory conditions are most likely to produce successful results. |
| FILED | Monday, February 27, 2017 |
| APPL NO | 15/444247 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 40/00 (20190201) G16B 40/20 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11546077 | Bernstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Liane Sarah Beland Bernstein (Cambridge, Massachusetts); Alexander Sludds (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | Deep neural networks (DNNs) have become very popular in many areas, especially classification and prediction. However, as the number of neurons in the DNN increases to solve more complex problems, the DNN becomes limited by the latency and power consumption of existing hardware. A scalable, ultra-low latency photonic tensor processor can compute DNN layer outputs in a single shot. The processor includes free-space optics that perform passive optical copying and distribution of an input vector and integrated optoelectronics that implement passive weighting and the nonlinearity. An example of this processor classified the MNIST handwritten digit dataset (with an accuracy of 94%, which is close to the 96% ground truth accuracy). The processor can be scaled to perform near-exascale computing before hitting its fundamental throughput limit, which is set by the maximum optical bandwidth before significant loss of classification accuracy (determined experimentally). |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673268 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0675 (20130101) Transmission H04B 10/541 (20130101) H04B 10/614 (20130101) Multiplex Communication H04J 14/0224 (20130101) H04J 14/0234 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11540723 | Reifman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The Government of the United States as represented by the Secretary of the Army (Ft. Detrick, Maryland) |
| INVENTOR(S) | Jaques Reifman (New Market, Maryland); Srinivas Laxminarayan (Frederick, Maryland); Vineet Rakesh (Frederick, Maryland); Sridhar Ramakrishnan (Frederick, Maryland); Jianbo Liu (Lexington, Virginia) |
| ABSTRACT | A method of estimating a body temperature of an individual based on physiological data including a heart rate received from at least one sensor 510 and received environmental data. The physiological data and the environmental data are inputted into a model present on a processor 520. The model generates an estimated body temperature and an estimated physiological condition based on the inputs. The processor 520 compares the estimated physiological condition to a measured physiological condition in the physiological data. A controller 530 modifies at least one parameter in the model when the difference between the estimated physiological condition and the measured physiological condition is above a threshold. |
| FILED | Monday, September 28, 2020 |
| APPL NO | 17/034785 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) Original (OR) Class A61B 5/0008 (20130101) A61B 5/024 (20130101) A61B 5/681 (20130101) A61B 5/02055 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/5006 (20130101) H04L 43/08 (20130101) H04L 67/535 (20220501) Wireless Communication Networks H04W 4/70 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11540900 | Liacouras et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter Liacouras (North Potomac, Maryland); Michael Yang (Iwakuni, Japan) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Peter Liacouras (North Potomac, Maryland); Michael Yang (Iwakuni, Japan) |
| ABSTRACT | The subject matter of the instant invention relates to a dental implant surgical apparatus and system comprising a customized dental ridge augmentation matrix and one or, optionally, a plurality of dental implant surgical drill guides, and methods of use thereof. |
| FILED | Thursday, May 02, 2019 |
| APPL NO | 16/401273 |
| ART UNIT | 3772 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 1/084 (20130101) Original (OR) Class A61C 13/01 (20130101) A61C 13/0004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541215 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRITON SYSTEMS, INC. (Chelmsford, Massachusetts) |
| ASSIGNEE(S) | TRITON SYSTEMS, INC. (Chelmsford, Massachusetts) |
| INVENTOR(S) | Yoojeong Kim (Sudbury, Massachusetts); Sarena Horava (Medway, Massachusetts); Anant Singh (Woburn, Massachusetts) |
| ABSTRACT | An endoscope may include a needle and a scope, which may optionally be contained in an elongated shaft. The endoscope may further include a handle comprising at least one button, a visualization component, a reservoir configured to contain a composition, and a dispensing mechanism. The at least one button, the needle, the reservoir, and the dispensing mechanism may be operably linked to cause the composition to be dispensed from the reservoir through the needle to a portion of an ear. A method for using such an endoscope may include inserting the endoscope into a portion of an ear, using the visualization component to visualize the portion of the ear, and pressing the at least one button to dispense the composition from the reservoir through the needle to the portion of the ear. |
| FILED | Wednesday, September 25, 2019 |
| APPL NO | 16/581925 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/00066 (20130101) A61B 1/00165 (20130101) A61B 1/00195 (20130101) A61B 1/227 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/00 (20130101) Original (OR) Class A61M 2205/3306 (20130101) A61M 2210/0662 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541239 | Tracey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York) |
| ASSIGNEE(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| INVENTOR(S) | Kevin J. Tracey (Old Greenwich, Connecticut); Sangeeta S. Chavan (Syosset, New York) |
| ABSTRACT | Methods are disclosed for treating a subject having a disease or disorder comprising stimulating a nerve of the subject with a corrective stimulus pattern derived from a disease-specific, condition-specific, endogenous mediator-specific or pharmacologic agent-specific neurogram in an amount and manner effective to treat the disease or disorder. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 16/695557 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36002 (20170801) A61N 1/36007 (20130101) A61N 1/36053 (20130101) A61N 1/36071 (20130101) A61N 1/36135 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541611 | Rice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kineticure, LLC (Miamisburg, Ohio) |
| ASSIGNEE(S) | Kineticure, LLC (Miamisburg, Ohio) |
| INVENTOR(S) | Jason P. Rice (Dayton, Ohio); Mark C. Cridge (Miamisburg, Ohio); Christopher D. Hemmelgarn (South Charleston, Ohio); Patrick J. Hood (Bellbrook, Ohio); Tat Hung Tong (Bellbrook, Ohio) |
| ABSTRACT | Systems for positioning and bonding a nutplate to a substrate having an aperture include a nutplate engagement fixture and a temperature sensor retention fixture. The nutplate engagement fixture includes a rigid tube and an elastomeric tube engaged with the rigid tube, the elastomeric tube having an elongated tube sized to provide a friction fit with the aperture and retain the elastomeric tube within the aperture. The rigid tube is operable to engage the nutplate at one end and the elastomeric tube is configured to anchor the nutplate engagement fixture at the aperture and secure the nutplate in contact with the substrate. The temperature sensor retention fixture includes a fixture body sized and configured to engage with the nutplate and at least one passageway within the fixture body sized and configured to allow a temperature sensor to be inserted or embedded therein with an end proximal a surface of the nutplate. |
| FILED | Tuesday, December 22, 2020 |
| APPL NO | 17/130227 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/72 (20130101) B29C 65/561 (20130101) B29C 65/565 (20130101) B29C 65/4835 (20130101) B29C 65/7838 (20130101) Original (OR) Class B29C 65/7844 (20130101) B29C 65/8261 (20130101) B29C 66/301 (20130101) B29C 66/712 (20130101) B29C 66/742 (20130101) B29C 66/3032 (20130101) B29C 66/5221 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2023/003 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/08 (20130101) B32B 2597/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11541801 — Method and apparatus for positioning the center of mass on an unmanned underwater vehicle
| US 11541801 | Seeley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Eric Seeley (Seabeck, Washington) |
| ABSTRACT | A field configurable autonomous vehicle includes modular elements and attachable components. The vehicle can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed vehicles for each mission. The vehicle can include a module that enables the vehicle to adjust the position of the center of mass to trim the vehicle for efficient operations or to alter the stability and control parameters of the vehicle. |
| FILED | Saturday, September 12, 2020 |
| APPL NO | 16/974046 |
| ART UNIT | 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects B60P 3/00 (20130101) Original (OR) Class Ships or Other Waterborne Vessels; Equipment for Shipping B63B 3/08 (20130101) B63B 43/08 (20130101) B63B 73/10 (20200101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/24 (20130101) B63G 2008/002 (20130101) Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2211/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541995 | Parsons |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| ASSIGNEE(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| INVENTOR(S) | Eric S. Parsons (Middlebury, Connecticut) |
| ABSTRACT | A structural member for use in a rotor system which rotates about a rotational axis includes a pin which extends substantially perpendicular to the rotational axis, a filler component positioned adjacent the pin, and a plurality of layers of composite material having fibers oriented lengthwise along a central axis which is perpendicular to the rotational axis. The plurality of fibers in the layers of composite material is wrapped about the pin and the filler component such that the fibers extend along the central axis and the plurality of layers form an opening filled by the filler component and which decreases as a function of distance from the pin along the central axis. |
| FILED | Tuesday, July 14, 2020 |
| APPL NO | 16/928605 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/33 (20130101) B64C 27/48 (20130101) Original (OR) Class B64C 27/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542030 | Fechtmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America, as represented by the Secretary of the Navy (Patuxent River, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Michael Fechtmann (Lusby, Maryland); Nathan Tenney (Hollywood, Maryland) |
| ABSTRACT | A self-heating and self-sealing bladder comprising of a fuel and water resistant layer overlaid on a mold; an adhesive tack layer overlaid on the fuel and water resistant layer; a first fabric reinforcement layer overlaid on the adhesive tack layer; a microballoon powder, water containing microspheres, and reactive salt powders disposed in a plurality of pouches such that upon activation the microballoon powder and the reactive salt powders come in contact with the water and react to create a formulation that results in heat and expansion, thus a self-sealing capability; and, a second fabric reinforcement layer overlaid the plurality of pouches. |
| FILED | Thursday, October 07, 2021 |
| APPL NO | 17/496171 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 15/03177 (20130101) B60K 2015/03407 (20130101) B60K 2015/03447 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 37/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542042 | Daniels et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Keir Daniels (New York, New York); Zachary Switzer (Washington, District of Columbia); Dimitris Kiaoulias (Washington, District of Columbia); Michael Keidar (Baltimore, Maryland) |
| ABSTRACT | A matrix thruster that may be used to reposition and/or stabilize a CubeSAT satellite. The matrix thruster includes a conductive plate with an opening, a plurality of wires within the opening, a power supply electrically connected to the conductive plate or each of the plurality of wires via an inductor, and an electrical switch. The electrical switch creates a current change that creates an electric potential spike across the inductor. The electric potential spike across the inductor initiates an arc discharge between one of the wires and the conductive plate, which forms plasma that ejects cathode particles from the matrix thruster. Using multiple wires (e.g., four titanium wires) extends the lifetime of the thruster, as each wire restores an inter-electrode film needed for the other wires to continue generating plasma. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/021019 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/105 (20130101) B64G 1/405 (20130101) Original (OR) Class B64G 1/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542250 | Ji |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Haitao Ji (Tampa, Florida) |
| ABSTRACT | Disclosed are inhibitors for the β-catenin/BCL9 interaction. The inhibitors are selective for β-catenin/BCL9 over β-catenin/cadherin interactions. Methods of using the disclosed compounds to treat cancer are also disclosed. |
| FILED | Monday, December 17, 2018 |
| APPL NO | 16/954095 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/12 (20130101) C07D 401/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542254 | Ji et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSISITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Haitao Ji (Salt Lake City, Utah); Min Zhang (Salt Lake City, Utah) |
| ABSTRACT | In one aspect, the invention relates to 4-substituted benzoylpiperazine-1-substituted carbonyls having a structure represented by a formula: derivatives thereof, and related compounds; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders, e.g., various tumors and cancers, associated with β-catenin/BCL9 protein-protein interaction dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 16/087553 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 403/12 (20130101) Original (OR) Class C07D 403/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542305 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Xiaojing Gao (Los Angeles, California); Michael B. Elowitz (Los Angeles, California) |
| ABSTRACT | Disclosed herein include methods, compositions, and kits suitable for use in detecting the activation level of a signal transducer. In some embodiments, there are provided synthetic protein circuits wherein recruitment of synthetic protein circuit components to an association location upon activation of a signal transducer generates an active effector protein. The effector protein can be configured to carry out a variety of functions when in an active state, such as, for example, inducing cell death. Methods of treating a disease or disorder characterized by aberrant signaling are provided in some embodiments. |
| FILED | Thursday, August 29, 2019 |
| APPL NO | 16/556063 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/001 (20130101) Original (OR) Class C07K 14/47 (20130101) C07K 2319/02 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/506 (20130101) Enzymes C12Y 304/22044 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542320 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of Americas, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jinny Lin Liu (Ellicott City, Maryland); George P. Anderson (Bowie, Maryland); Ellen R. Goldman (Germantown, Maryland) |
| ABSTRACT | Described herein are nucleic acids encoding single-domain antibodies that might serve as alternatives to conventional monoclonal antibodies for either the detection or treatment of Chikungunya Virus (CHIKV). |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/245180 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/1081 (20130101) Original (OR) Class C07K 2317/22 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/36111 (20130101) C12N 2770/36123 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542545 | Ismagilov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); Talis Biomedical Corporation (Redwood City, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); Talis Biomedical Corporation (Redwood City, California) |
| INVENTOR(S) | Rustem F. Ismagilov (Altadena, California); Eugenia Khorosheva (South Pasadena, California); Travis S. Schlappi (Pasadena, California); Matthew S. Curtis (Pasadena, California); Nathan G. Schoepp (Pasadena, California); Hedia Maamar (San Jose, California); Feng Shen (San Jose, California); Erik B. Jue (Pasadena, California) |
| ABSTRACT | Disclosed herein are methods and devices for rapid assessment of whether a microorganism present in a sample is susceptible or resistant to a treatment. |
| FILED | Thursday, November 05, 2015 |
| APPL NO | 15/524449 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 7/00 (20130101) B01L 2300/0861 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) C12Q 1/686 (20130101) C12Q 1/689 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6851 (20130101) Original (OR) Class C12Q 2537/165 (20130101) C12Q 2545/114 (20130101) C12Q 2565/629 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542635 | Schulz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | UNIVERSITY OF CINCINNATI (Cincinnati, Ohio) |
| INVENTOR(S) | Mark J. Schulz (West Chester, Ohio); Sathya Kanakaraj (Cincinnati, Ohio); David Mast (Cincinnati, Ohio); Vesselin Shanov (Cincinnati, Ohio); Devika Chauhan (Cincinnati, Ohio); Guangfeng Hou (Perrysburg, Ohio); Vianessa Ng (Miami, Florida); Chenhao Xu (Lakeside Park, Kentucky); Rui Daniel Chen (Cincinnati, Ohio); Ashley Kubley (Cincinnati, Ohio); Xiaoda Hou (Fruitland Park, Florida); Richard Kleismit (Cincinnati, Ohio); Zhangzhang Yin (Monroeville, Pennsylvania) |
| ABSTRACT | Carbon nanotube (CNT) fiber and sheets formed by a specialized gas assembly pyrolytic reactor method that permits gas phase integration of nano and micro particles (NMPs) are processed into yarn and fabric used in the manufacture of personal protective clothing and equipment that can be tailored via selection of NMPs for a wide variety of functionality depending on target application. The CNT-NMP hybrid fabrics may be designed to exhibit enhanced electrical and thermal conductivity, moisture wicking, air filtering, and environmental sensing properties. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/629714 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/127 (20130101) Original (OR) Class Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/40 (20130101) D02G 3/047 (20130101) D02G 3/441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542864 | Bryan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | ROLLS-ROYCE NORTH AMERICAN TECHNOLOGIES INC. (Indianapolis, Indiana) |
| INVENTOR(S) | William Barry Bryan (Indianapolis, Indiana) |
| ABSTRACT | A turbofan engine has a fan portion in fluid communication with a core stream and a bypass stream of air separated by splitters disposed both upstream and downstream of the fan portion. A blade splitter (shroud) on the fan partially spans the fan blade thus separating the core and bypass streams downstream while leaving a gap upstream for communication between the flows. The communication gap expands the operational range of the fan over fans without the communication gap. |
| FILED | Monday, April 29, 2019 |
| APPL NO | 16/397854 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/02 (20130101) F01D 17/162 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/04 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/14 (20130101) F05D 2240/55 (20130101) F05D 2240/122 (20130101) F05D 2240/301 (20130101) F05D 2240/304 (20130101) F05D 2260/606 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542926 | Dragnea et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Horatiu C. Dragnea (Plaza del Rey, California); Henry Helvajian (Pasadena, California); Kushal Patel (Whittier, California) |
| ABSTRACT | A vehicle comprising a structure, a plurality of heating sources, and a transport mechanism. The structure is comprised of multiple materials, a composite such that some of the material constituents can be extracted leaving behind others via application of energy (such as de-alloying). The extracted material or materials are configured to be re-purposed into a propellant. The plurality of heating elements surrounds or is embedded within the structure configured to convert the material into the propellant. The transport mechanism is configured to transport the propellant from the structure to a reservoir or to the propulsion system. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/897193 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Jet-propulsion Plants F02K 9/08 (20130101) F02K 9/32 (20130101) F02K 9/36 (20130101) F02K 9/42 (20130101) F02K 9/44 (20130101) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0037 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543014 | Helton |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Justin R. Helton (Fredericksburg, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Justin R. Helton (Fredericksburg, Virginia) |
| ABSTRACT | A method is provided for producing gears to balance counteracting gravity moment and a torque equilibrator across an elevation range. The method includes assigning a value to summation of pitch radii of the first and second non-circular gears; calculating a torque for both the non-circular gears for an angle within the elevation range; calculating a first pitch radius of the first non-circular gear by the gravity moment and the torsion equilibrator; calculating a second pitch radius of the second non-circular gear from the summation; and fabricating the non-circular gears based on the first and second pitch radii. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 16/851398 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Making Gears or Toothed Racks B23F 15/00 (20130101) Gearing F16H 19/001 (20130101) F16H 57/00 (20130101) Original (OR) Class F16H 2057/0087 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 1/12 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49476 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543358 | Swager et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambrige, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); Joseph M. Azzarelli (Cambridge, Massachusetts); Kathleen R. White (Dubuque, Iowa) |
| ABSTRACT | A detector can detect an analyte including a carbon-carbon multiple bond moiety and capable of undergoing Diels-Alder reaction with a heteroaromatic compound having an extrudable group. The detector can detect, differentiate, and quantify ethylene. |
| FILED | Monday, January 27, 2020 |
| APPL NO | 16/773922 |
| ART UNIT | 1796 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class G01N 2021/7786 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543399 | Kelley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jude A. Kelley (Sutton, Massachusetts); Roderick Russell Kunz (Acton, Massachusetts); Alla Ostrinskaya (Needham, Massachusetts); Richard Paul Kingsborough (Groton, Massachusetts) |
| ABSTRACT | The use of volatilization reagents is disclosed for improved detection of inorganic oxidizers such as, but not limited to, chlorates and perchlorates. Detection methods are disclosed whereby a reagent can transfer a proton to the anion (i.e., chlorate, perchlorate, etc.) of an inorganic salt analyte, forming an acid (i.e., chloric acid, perchloric acid) that is easier to detect by a mechanism whereby the acidified reagent is more easily vaporized, and hence, more easily detected. Concurrently, the anion of the acid forms a new salt with the cation released from the salt that was acidified. The reagents can also include acidic salts or cation-donators, more generally. In some embodiments, hydrated reagents or co-reagents that can release water can be employed. |
| FILED | Tuesday, July 09, 2019 |
| APPL NO | 16/506780 |
| ART UNIT | 1796 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/623 (20210101) G01N 33/227 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/19 (20150115) Y10T 436/24 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543429 | Ozturk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Morgan State University (Baltimore, Maryland) |
| ASSIGNEE(S) | Morgan State University (Baltimore, Maryland) |
| INVENTOR(S) | Birol Ozturk (Parkville, Maryland); Alperen Guver (Baltimore, Maryland); Peker Milas (Baltimore, Maryland) |
| ABSTRACT | Disclosed is a method for preparing nanoscale electrodes comprised of electrochemically grown noble metal nanowires, and use of the same for the detection of extremely small concentrations of molecules. Such nanoscale electrodes provide target molecule release information from submicron areas on the cell surface, significantly increasing the spatial resolution of the target molecule mapping of a cell surface to enable localization of target molecules on the cell surface, which can be critical for the detection of certain cells with different properties in a given group of cells, such as circulating tumor cells. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/857821 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5438 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/60 (20130101) Original (OR) Class G01Q 70/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543571 | Cleary et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Justin W. Cleary (Miamisburg, Ohio); Evan M. Smith (Dayton, Ohio); Ricky D. Gibson, Jr. (Hilliard, Ohio); Shivashankar R. Vangala (Mason, Ohio); Joshua Hendrickson (Dayton, Ohio); Ivan Avrutsky (Rochester Hills, Michigan) |
| ABSTRACT | A transmission filter apparatus is provided that includes: (i) a substrate to serve as a foundation for the apparatus; (ii) a layer containing resonant dielectric cavities separated by conductive regions. The dimensions and design of the dielectric cavities, thickness of the layer, and substrate, dielectric and conductive materials are chosen to achieve resonant transmission of selected wavelengths. In a particular one or more embodiments, the layer is one dimensional, i.e. you have dielectric cavities along one axis in the plane that are comparatively infinity long in the parallel plane. In a particular one or more embodiments, the layer is two dimensional, i.e. you have dielectric cavities along both axis in the plane. The dimensions in each plane may or may not be equal. In a specific one or more embodiments, the dielectric cavities are terminated on the top and/or bottom by thin metal films with small apertures or tapers. |
| FILED | Tuesday, June 16, 2020 |
| APPL NO | 16/902672 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/284 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543653 | Fan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Jonathan A. Fan (Palo Alto, California); David Sell (Stanford, California); Jianji Yang (Menlo Park, California) |
| ABSTRACT | Various embodiments are directed to an apparatus and methods of forming and/or using an apparatus comprising a plurality of device components. An example method includes geometrically optimizing a periodic or aperiodic device comprising a plurality of device components by optimizing a topology, for each device component, from a starting point to have particular optical properties for a particular optical response. Each device component includes a plurality of geometric structures. The optimization includes selecting the starting point for a continuous profile to have the particular optical properties for the particular optical response, iteratively converging the continuous profile to a discrete profile, and, while iteratively converging to the discrete profile, adjusting edges between boundaries of the device components by accounting for fabrication constraints. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/937258 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/18 (20130101) G02B 27/0012 (20130101) Original (OR) Class G02B 2005/1804 (20130101) G02B 2207/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543774 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | David R. Smith (Durham, North Carolina); Zhiqin Huang (Chapel Hill, North Carolina); Daniel L. Marks (Durham, North Carolina) |
| ABSTRACT | Various examples of out-of-plane multicolor waveguide holography systems, methods of manufacture, and methods of use are described herein. In some examples, a multicolor waveguide holography system includes a planar waveguide to convey optical radiation between a grating coupler and a metasurface hologram. The grating coupler may be configured to couple out-of-plane optical radiation of three different color incident at three different angles into the planar waveguide. The combined multicolor optical radiation may be conveyed by the waveguide to the metasurface hologram. The metasurface hologram may diffractively decouple the three colors of optical radiation for off-plane propagation to form a multicolor holographic image in free space. |
| FILED | Monday, July 01, 2019 |
| APPL NO | 16/459045 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/2645 (20130101) Original (OR) Class G03H 2222/13 (20130101) G03H 2223/23 (20130101) G03H 2225/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543806 | Crawford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Lara S. Crawford (Belmont, California); Morad Behandish (Foster City, California) |
| ABSTRACT | One embodiment of the present disclosure provides a system and method for facilitating a search for a hybrid-manufacturing process plan for manufacturing an object. During operation, the system can obtain a set of partial order constraints constraining the order in which a set of at least two manufacturing actions, corresponding to addition or removal of predefined regions of space, appear in a process plan. The system can constrain, based on the set of partial order constraints, a search space. The search space can correspond to a tree in which the nodes represent the object's state and the edges represent available actions at each node. The system can then determine a set of optimized process plans represented by orderings of the actions, corresponding to paths on the search tree, that produce the desired final state in a cost-effective manner. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/140915 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1656 (20130101) B25J 9/1664 (20130101) B25J 9/1666 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/41865 (20130101) Original (OR) Class Electric Digital Data Processing G06F 16/20 (20190101) G06F 16/9024 (20190101) G06F 16/9027 (20190101) G06F 16/24542 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544422 | Matei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Ion Matei (Sunnyvale, California); Maksym Zhenirovskyy (Mountain View, California); Johan de Kleer (Los Altos, California); Alexander Feldman (Santa Cruz, California) |
| ABSTRACT | The disclosure following relates generally to complex simulations, and fault diagnosis. In some embodiments, a component that is causing a delayed simulation time of a system is determined. A component of reduced complexity is designed, and the component of reduced complexity is used to replace the original component in the system. Fault diagnosis may then be conducted using the updated system with the reduced complexity component, thus decreasing the time taken to diagnose the fault. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572280 |
| ART UNIT | 2148 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 17/13 (20130101) G06F 17/16 (20130101) G06F 30/17 (20200101) Original (OR) Class G06F 30/20 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544435 | Korchemny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Synopsys, Inc. (Mountain View, California) |
| ASSIGNEE(S) | Synopsys, Inc. (Mountain View, California) |
| INVENTOR(S) | Dmitry Korchemny (Herzliya, Israel); Ilya Kudryavtsev (Herzliya, Israel); Eduard Cerny (Jupiter, Florida); Dmitriy Mosheyev (Herzliya, Israel) |
| ABSTRACT | The present disclosure generally relates to an analog mixed-signal (AMS) design verification system. In particular, the present disclosure relates to a system and method for system verification. One example method includes: obtaining an electronic representation of the circuit design; generating at least a portion of a waveform using the electronic representation of the circuit to obtain a first segment of the waveform associated with the circuit; converting, via the one or more processors, one or more measurement functions to code for performing the one or more computations on the first segment of the waveform; performing one or more computations on the first segment of the waveform using the code; and identifying when a behavior of the circuit violates a design specification based on whether a result of the one or more computations meets a threshold. |
| FILED | Monday, June 21, 2021 |
| APPL NO | 17/353208 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 30/38 (20200101) G06F 30/327 (20200101) G06F 30/367 (20200101) G06F 30/398 (20200101) G06F 30/3308 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544527 | Shu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Xiaokui Shu (Ossining, New York); Zhongshu Gu (Ridgewood, New Jersey); Marc P. Stoecklin (Richterswil, Switzerland); Hani T. Jamjoom (Cos Cob, Connecticut) |
| ABSTRACT | Mechanisms for identifying a pattern of computing resource activity of interest, in activity data characterizing activities of computer system elements, are provided. A temporal graph of the activity data is generated and a filter is applied to the temporal graph to generate one or more first vector representations, each characterizing nodes and edges within a moving window defined by the filter. The filter is applied to a pattern graph representing a pattern of entities and events indicative of the pattern of interest, to generate a second vector representation. The second vector representation is compared to the one or more first vector representations to identify one or more nearby vectors, and one or more corresponding subgraph instances are output to an intelligence console computing system as inexact matches of the temporal graph. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 16/783274 |
| ART UNIT | 2165 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9017 (20190101) G06F 16/9024 (20190101) G06F 16/9035 (20190101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6296 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/0436 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544574 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cadence Design Systems, Inc. (San Jose, California) |
| ASSIGNEE(S) | Cadence Design Systems, Inc. (San Jose, California) |
| INVENTOR(S) | Wangyang Zhang (Allison Park, Pennsylvania); Elias Lee Fallon (Allison Park, Pennsylvania) |
| ABSTRACT | The present disclosure relates to a computer-implemented method for electronic design. Embodiments may include receiving, using at least one processor, an electronic design schematic and optionally an electronic design layout. Embodiments may further include analyzing the electronic design schematic to determine if one or more required features of a particular circuit structure are present. If the one or more required features are present, embodiments may include analyzing, using a machine learning model, the electronic design schematic to determine if one or more optional features of the particular circuit structure are present. |
| FILED | Thursday, July 25, 2019 |
| APPL NO | 16/522035 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 30/398 (20200101) Computer Systems Based on Specific Computational Models G06N 5/003 (20130101) Original (OR) Class G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545040 | Kleveland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| ASSIGNEE(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| INVENTOR(S) | James Kleveland (Marion, Iowa); Korey Breger (Coralville, Iowa) |
| ABSTRACT | A computer apparatus includes a touchscreen display. The computer apparatus generates a graphical user interface on the touchscreen display and receive user inputs via the touchscreen display. The graphical user interface includes symbology representing a flight path of multiple unmanned teamed assets from a current position to a current objective. The graphical user interface also includes symbology representing a card associated with each of the unmanned teamed assets. By the touchscreen display, an operator selects one of the unmanned teamed assets, for emphasis of the flight path. The flight paths of the non-selected unmanned teamed assets remain displayed when the selected flight path is emphasized. The operator may select the unmanned teamed asset by the flight path or by the unmanned teamed asset card. |
| FILED | Tuesday, April 13, 2021 |
| APPL NO | 17/229585 |
| ART UNIT | 2175 — Graphical User Interface and Document Processing |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 43/00 (20130101) Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/0484 (20130101) G06F 3/0488 (20130101) Traffic Control Systems G08G 5/0069 (20130101) Original (OR) Class G08G 5/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545722 | Pol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Vilas Ganpat Pol (West Lafayette, Indiana); Patrick J H Kim (West Lafayette, Indiana) |
| ABSTRACT | Separators, materials, and processes for producing electrochemical cells, for example, lithium (Li) metal batteries, and electrochemical cells produced therefrom. Such a separator includes a permeable membrane formed of a first polymer that is hydrophobic and has oppositely-disposed first and second surfaces, a second polymer that is hydrophilic and is incorporated into the first surface of the first polymer so that the first surface of the first polymer is a hydrophilic surface, and a conductive composite layer on the hydrophilic surface. The composite layer contains at least one layer of a carbonaceous material and an aqueous binder that binds the carbonaceous material together and to the hydrophilic. |
| FILED | Monday, March 16, 2020 |
| APPL NO | 16/820235 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 10/052 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 50/411 (20210101) H01M 50/431 (20210101) H01M 50/449 (20210101) Original (OR) Class H01M 2300/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545724 | Frischmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SEPION TECHNOLOGIES, INC. (Emeryville, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Sepion Technologies. Inc. (Emeryville, California) |
| INVENTOR(S) | Peter David Frischmann (Berkeley, California); Brett Anthony Helms (Oakland, California) |
| ABSTRACT | A composite membrane with nanostructured inorganic and organic phases is applied as an ion-selective layer to prove processability, prevent dendrite shorting, and increase power output of lithium-metal anodes through better Li-ion conductivity. Nanoconfinement, as opposed to macroscale confinement, is known to dramatically alter the properties of bulk materials. Control over a ceramic's size, shape, and properties is achieved with polymer templates. This is a new composition of matter and unique approach to composite membrane design. |
| FILED | Thursday, December 07, 2017 |
| APPL NO | 16/465013 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 10/0525 (20130101) H01M 10/0569 (20130101) H01M 50/46 (20210101) Original (OR) Class H01M 50/446 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545780 | Roberts |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Harrison Roberts (Tucson, Arizona) |
| ABSTRACT | A cable connector including a housing with a main body having a front face opposite a rear face and pin holes formed through the main body extending between the front face and the rear face, a first arm and second arm extending from the main body distal from the rear face; a cover removably coupled to the front face, the cover including receivers configured to align with the pin holes to receive either a pin or a socket connected at a terminal end of a wire; fasteners removably coupled to the cover and the housing; at least one guide post extending from an outer surface of the cover; a collar supported between the first arm and the second arm; and a predetermined pattern of the wire coupled to at least one of the pin and the socket, wherein either the pin or the socket are insertable in the pin hole. |
| FILED | Thursday, September 02, 2021 |
| APPL NO | 17/465048 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/052 (20130101) H01R 13/514 (20130101) Original (OR) Class H01R 13/5812 (20130101) H01R 13/5837 (20130101) H01R 13/6271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11546539 | Gruev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Viktor Gruev (Urbana, Illinois); Missael Garcia (Urbana, Illinois) |
| ABSTRACT | A polarization imager is provided that includes a plurality of CMOS photodetectors and a plurality of polarization filters. Each of the plurality of CMOS photodetectors has a photodiode that is configured to operate in forward bias mode. Further, each of the plurality of polarization filters is monolithically integrated with a corresponding one of the plurality of CMOS photodetectors. Each of the plurality of photodiodes exhibits a logarithmic response to a flux of incident photons. The polarization imager achieves a dynamic range of at least 100 decibels with a signal-to-noise ratio of at least 60 decibels. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 16/585711 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14625 (20130101) H01L 27/14643 (20130101) Pictorial Communication, e.g Television H04N 5/37455 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11541550 | Baptist et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Joshua R. Baptist (Louisville, Kentucky); Mohammad Nasser Saadatzi (Louisville, Kentucky); Zhong Yang (Louisville, Kentucky); Ruoshi Zhang (Louisville, Kentucky); Dan O. Popa (Louisville, Kentucky) |
| ABSTRACT | A robot skin apparatus includes polymer membranes encapsulating a pressure sensor. The sensor includes piezo-sensitive material in contact with a pair of electrodes in spaced relationship to form a circuit. The apparatus may include a flexible substrate, with the electrodes thereon. The piezo-sensitive material may be piezoresistive film. The electrodes may be symmetrically patterned on the substrate to form a substantially circular peripheral boundary. The apparatus may include pressure sensors on opposite sides of a plane for temperature compensation, a plurality of pressure sensors arrayed on the substrate, and a data acquisition system. A method of fabricating the apparatus includes a wet lithography process for patterning the piezoresistive film. A system includes a pair of gripper fingers, an actuator connected to the fingers, a robot skin apparatus positioned on one of the fingers, and an electronic unit for receiving data from the robot skin and controlling the fingers. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 16/500295 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 13/084 (20130101) Original (OR) Class B25J 15/024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541559 | Lujan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOISE STATE UNIVERSITY (Boise, Idaho) |
| ASSIGNEE(S) | Boise State University (Boise, Idaho) |
| INVENTOR(S) | Trevor Lujan (Boise, Idaho); Sean Nelson (Meridian, Idaho); Madison Wale (Boise, Idaho); Danielle Siegel (Boise, Idaho); Jaremy Creechley (Laramie, Wyoming) |
| ABSTRACT | A system may include a blade die, a first clamping caul positioned on a first side of the blade die, and a second clamping caul positioned on a second side of the blade die. A molding surface of the blade die and a molding surface of the first clamping caul may be configured to bend a first interchangeable blade positioned therebetween into a first shape in response to a first compression force. A second molding surface of the blade die and a molding surface of the second clamping caul may be configured to bend a second interchangeable blade positioned therebetween into a second shape in response to a second compression force. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/234606 |
| ART UNIT | 3724 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2017/3225 (20130101) Hand-held Cutting Tools Not Otherwise Provided for B26B 5/006 (20130101) B26B 5/008 (20130101) Original (OR) Class B26B 9/02 (20130101) B26B 29/00 (20130101) Perforating; Punching; Cutting-out; Stamping-out; Severing by Means Other Than Cutting B26F 1/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542042 | Daniels et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Keir Daniels (New York, New York); Zachary Switzer (Washington, District of Columbia); Dimitris Kiaoulias (Washington, District of Columbia); Michael Keidar (Baltimore, Maryland) |
| ABSTRACT | A matrix thruster that may be used to reposition and/or stabilize a CubeSAT satellite. The matrix thruster includes a conductive plate with an opening, a plurality of wires within the opening, a power supply electrically connected to the conductive plate or each of the plurality of wires via an inductor, and an electrical switch. The electrical switch creates a current change that creates an electric potential spike across the inductor. The electric potential spike across the inductor initiates an arc discharge between one of the wires and the conductive plate, which forms plasma that ejects cathode particles from the matrix thruster. Using multiple wires (e.g., four titanium wires) extends the lifetime of the thruster, as each wire restores an inter-electrode film needed for the other wires to continue generating plasma. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/021019 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/105 (20130101) B64G 1/405 (20130101) Original (OR) Class B64G 1/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542215 | Veige et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Adam S. Veige (Gainesville, Florida); Brent S. Sumerlin (Gainesville, Florida); Zhihui Miao (Gainesville, Florida) |
| ABSTRACT | Disclosed herein are methods for removing acetylene from an ethylene gas stream wherein a catalyst reacts with the acetylene to polymerize said acetylene forming an ethylene gas stream substantially free of acetylene. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/032663 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/864 (20130101) B01D 2255/20776 (20130101) Acyclic or Carbocyclic Compounds C07C 7/177 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 110/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542378 | Teipel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ESSENTIUM, INC. (Pflugerville, Texas) |
| ASSIGNEE(S) | Essentium IPCO, LLC (Pflugerville, Texas) |
| INVENTOR(S) | Elisa Teipel (Pflugerville, Texas); Kevin Holder (Houston, Texas); Nirup Nagabandi (Pflugerville, Texas); Blake Teipel (Pflugerville, Texas) |
| ABSTRACT | A thermoplastic composite material includes a thermoplastic polymer matrix component, a microparticle component, a nanoparticle component, and a compatibilizing agent component, at least a portion of the microparticle component and/or nanoparticle component is a natural fiber. |
| FILED | Tuesday, June 05, 2018 |
| APPL NO | 16/619008 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/10 (20130101) C08J 5/042 (20130101) C08J 5/043 (20130101) C08J 5/045 (20130101) C08J 7/0427 (20200101) Original (OR) Class C08J 2323/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542454 | Kraus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | George A. Kraus (Ames, Iowa); Kyle Podolak (Ames, Iowa); Derek Lee White (Lakewood, Colorado); Sriram Sundararajan (Ames, Iowa) |
| ABSTRACT | The present invention is toward a base oil or lubricant additives, methods of using the same, lubricant compositions including the same, and methods of forming the lubricant compositions. A base oil or lubricant additive has Structure I or Structure II as described herein. |
| FILED | Tuesday, July 20, 2021 |
| APPL NO | 17/380766 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 129/70 (20130101) Original (OR) Class C10M 169/04 (20130101) C10M 2203/003 (20130101) C10M 2207/281 (20130101) C10M 2207/284 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2030/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542509 | Maianti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Juan Pablo Maianti (Revere, Massachusetts); David R. Liu (Lexington, Massachusetts); Luke W. Koblan (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are systems, compositions, and methods for the incorporation of unnatural amino acids into proteins via nonsense suppression or rare codon suppression. Nonsense codons and rare codons may be introduced into the coding sequence of a protein of interest using a CRISPR/Cas9-based nucleobase editor described herein. The nucleobase editors are able to be programmed by guide nucleotide sequences to edit the target codons in the coding sequence of the protein of interest. Also provided are application enabled by the technology described herein. |
| FILED | Thursday, August 24, 2017 |
| APPL NO | 16/327744 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/78 (20130101) C12N 15/67 (20130101) Original (OR) Class C12N 15/102 (20130101) Enzymes C12Y 305/04001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542512 | Keasling et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jay D. Keasling (Berkeley, California); Leo D'Espaux (San Francisco, California); Jeff Wong (Berkeley, California); Xiaozhou Luo (Berkeley, California); Michael Reiter (Berkeley, California); Charles Denby (Berkeley, California); Anna Lechner (Berkeley, California) |
| ABSTRACT | The present disclosure provides genetically modified host cells that produce a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. The present disclosure provides methods of synthesizing a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/206126 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 63/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1085 (20130101) C12N 15/52 (20130101) C12N 15/70 (20130101) C12N 15/81 (20130101) Original (OR) Class C12N 15/8243 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Enzymes C12Y 101/01088 (20130101) C12Y 203/0301 (20130101) C12Y 203/01086 (20130101) C12Y 203/01206 (20150701) C12Y 205/01102 (20150701) C12Y 207/01036 (20130101) C12Y 207/04002 (20130101) C12Y 401/01033 (20130101) C12Y 503/03002 (20130101) C12Y 602/01003 (20130101) C12Y 604/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542520 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Ling Li (Mississippi State, Mississippi); Eve Syrkin Wurtele (Ames, Iowa) |
| ABSTRACT | Method of increasing protein content in a eukaryotic cell comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site; method of producing a plant with increased protein content comprising crossing and selecting for increased protein content; method of increasing resistance to a pathogen or a pest in a plant cell or plant comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site, alone or in further combination with expressing QQS in the plant cell or plant; method for producing a plant with increased resistance to a pathogen or a pest comprising crossing and selecting for increased resistance to the pathogen or the pest; a cell, collection of cells, tissue, organ, or organism, such as a plant, in which the NF-YC4 gene comprises a promoter comprising a transcriptional repressor binding site that has been modified so that the transcriptional repressor cannot prevent transcription of the NF-YC4; plants and hybrids thereof; and seeds. |
| FILED | Saturday, April 04, 2020 |
| APPL NO | 16/840354 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/02 (20130101) Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8205 (20130101) C12N 15/8216 (20130101) C12N 15/8241 (20130101) C12N 15/8247 (20130101) C12N 15/8251 (20130101) Original (OR) Class C12N 15/8279 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542538 | Jewett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Jessica Carol Stark (Evanston, Illinois); Matthew P. DeLisa (Ithaca, New York); Thapakorn Jaroentomeechai (Ithaca, New York) |
| ABSTRACT | Disclosed are methods, systems, components, and compositions for cell-free synthesis of glycosylated proteins. The glycosylated proteins may be utilized in vaccines, including anti-bacterial vaccines. The glycosylated proteins may include a bacterial polysaccharide conjugated to a carrier, which may be utilized to generate an immune response in an immunized host against the polysaccharide conjugated to the carrier. The glycosylated proteins may be synthesized in cell-free glycoprotein synthesis (CFGpS) systems using prokaryote cell lysates that are enriched in components for glycoprotein synthesis such as oligosaccharyltransferases (OSTs) and lipid-linked oligosaccharides (LLOs) including OSTs and LLOs associated with synthesis of bacterial O antigens. |
| FILED | Thursday, October 22, 2020 |
| APPL NO | 17/077354 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/04 (20130101) A61K 38/16 (20130101) A61K 39/0208 (20130101) A61K 39/0258 (20130101) A61K 2039/6037 (20130101) A61K 2039/6068 (20130101) Peptides C07K 7/06 (20130101) C07K 9/00 (20130101) C07K 14/00 (20130101) C07K 14/47 (20130101) C07K 2319/91 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/00 (20130101) C12N 1/205 (20210501) C12N 9/10 (20130101) C12N 9/1081 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/00 (20130101) C12P 21/00 (20130101) C12P 21/02 (20130101) C12P 21/005 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/00 (20210501) C12R 2001/19 (20210501) C12R 2001/145 (20210501) Enzymes C12Y 204/99019 (20150701) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542542 | Lease |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Richard A. Lease (Westerville, Ohio) |
| ABSTRACT | The present disclosure relates to improved methods for detecting nucleic acids using DNA fingerloop stem loop structures, wherein the DNA fingerloop stem loop structures diminish base pairing of a detection probe to a mismatched target nucleic acid. The present disclosure also relates to improved methods for amplifying nucleic acids. Further disclosed are chimeric fingerloop DNAs for use in methods for modulating protein expression levels and/or RNA stability. |
| FILED | Wednesday, July 18, 2018 |
| APPL NO | 16/631937 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) C12N 15/74 (20130101) C12N 2800/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542554 | Daugharthy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Evan R. Daugharthy (Cambridge, Massachusetts); Richard C. Terry (Carlisle, Massachusetts); Je-Hyuk Lee (Allston, Massachusetts); George M. Church (Brookline, Massachusetts); Benjamin W. Pruitt (Cambridge, Massachusetts) |
| ABSTRACT | Methods of volumetric imaging of a three-dimensional matrix of nucleic acids within a cell is provided. An automated apparatus for sequencing and volumetric imaging of a three-dimensional matrix of nucleic acids is provided. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/395534 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6841 (20130101) C12Q 1/6841 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2543/101 (20130101) C12Q 2543/101 (20130101) C12Q 2563/159 (20130101) C12Q 2563/159 (20130101) C12Q 2565/601 (20130101) C12Q 2565/601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542635 | Schulz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | UNIVERSITY OF CINCINNATI (Cincinnati, Ohio) |
| INVENTOR(S) | Mark J. Schulz (West Chester, Ohio); Sathya Kanakaraj (Cincinnati, Ohio); David Mast (Cincinnati, Ohio); Vesselin Shanov (Cincinnati, Ohio); Devika Chauhan (Cincinnati, Ohio); Guangfeng Hou (Perrysburg, Ohio); Vianessa Ng (Miami, Florida); Chenhao Xu (Lakeside Park, Kentucky); Rui Daniel Chen (Cincinnati, Ohio); Ashley Kubley (Cincinnati, Ohio); Xiaoda Hou (Fruitland Park, Florida); Richard Kleismit (Cincinnati, Ohio); Zhangzhang Yin (Monroeville, Pennsylvania) |
| ABSTRACT | Carbon nanotube (CNT) fiber and sheets formed by a specialized gas assembly pyrolytic reactor method that permits gas phase integration of nano and micro particles (NMPs) are processed into yarn and fabric used in the manufacture of personal protective clothing and equipment that can be tailored via selection of NMPs for a wide variety of functionality depending on target application. The CNT-NMP hybrid fabrics may be designed to exhibit enhanced electrical and thermal conductivity, moisture wicking, air filtering, and environmental sensing properties. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/629714 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/127 (20130101) Original (OR) Class Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/40 (20130101) D02G 3/047 (20130101) D02G 3/441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543306 | Kagan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Cherie R. Kagan (Bala Cynwyd, Pennsylvania); Kevin Turner (Wayne, Pennsylvania); Wenxiang Chen (Urbana, Illinois); Yijie Jiang (Corinth, Texas) |
| ABSTRACT | Provided are structurally-reconfigurable, optical metasurfaces constructed by, for example, integrating a plasmonic lattice array in the gap between a pair of microbodies that serve to locally amplify the strain created on an elastomeric substrate by an external mechanical stimulus. The spatial arrangement and therefore the optical response of the plasmonic lattice array is reversible. |
| FILED | Monday, September 21, 2020 |
| APPL NO | 17/026468 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/441 (20130101) A61B 2562/0261 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/18 (20130101) Original (OR) Class G01L 1/2287 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543365 | Sappok et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CTS CORPORATION (Lisle, Illinois) |
| ASSIGNEE(S) | CTS CORPORATION (Lisle, Illinois) |
| INVENTOR(S) | Alexander Sappok (Cambridge, Massachusetts); Paul Ragaller (Dorchester, Massachusetts); Leslie Bromberg (Sharon, Massachusetts) |
| ABSTRACT | A measurement system and method of conducting cavity resonance and waveguide measurements is disclosed. The cavity or waveguide may be used to monitor the amount, composition, or distribution of a material or sample contained in the cavity or waveguide or passing through the cavity or waveguide. Improved means for operating the measurement system to reduce measurement variability, improve measurement accuracy, and decrease measurement response times are described. The invention's broad applications range from measurements of filters, catalysts, pipe, and ducts where the material collected in or passing through the cavity or waveguide exhibits dielectric properties different from the material which it displaces. |
| FILED | Monday, October 12, 2020 |
| APPL NO | 17/068097 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 22/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543486 | Przybyla et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Invensense, Inc. (San Jose, California) |
| ASSIGNEE(S) | InvenSense, Inc. (San Jose, California) |
| INVENTOR(S) | Richard J. Przybyla (Emeryville, California); Ryan Young (El Cerrito, California); Mitchell H. Kline (Alameda, California); David A. Horsley (Berkeley, California) |
| ABSTRACT | Time of flight between two or more ultrasonic transceivers is measured using known delays. First and second transceivers are duty cycled, each having a respective receive period that is less than a measurement period during which the transceivers are configured to receive transmissions. An ultrasonic trigger pulse is transmitted by the first transceiver. The second transceiver, upon receiving the trigger pulse, transmits an ultrasonic response pulse after a first predefined delay time that is known to the first transceiver and greater than the receive period of the second transceiver. Subsequently, the first transceiver receives the ultrasonic response pulse and determines a receive time. The first transceiver determines the distance between the first transceiver and the second transceiver from a speed of sound, an elapsed time between the time of transmission of the trigger pulse and the receive time, and the first predetermine delay time. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/156242 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/808 (20130101) Original (OR) Class G01S 5/30 (20130101) G01S 15/876 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543933 | Piya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Cecil Piya (West Lafayette, Indiana); Vinayak Raman Krishnamurthy (West Lafayette, Indiana); Karthik Ramani (West Lafayette, Indiana) |
| ABSTRACT | A method of manipulating a three-dimensional image file including a virtual object includes obtaining image information in a processing device of a non-instrumented physical object manipulated by a user, such image information including movement information; and causing virtual movement of the virtual object based on the movement information. A method of shaping a virtual object includes obtaining image information including movement information; and determining a shape of the virtual object based on the movement information. A method of modifying a virtual object includes obtaining image information including movement information; and altering a virtual surface appearance of at least a part of the virtual object based on the movement information. Systems and computer-readable media are also described. |
| FILED | Thursday, January 23, 2020 |
| APPL NO | 16/751093 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/04815 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544522 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Fangxing Li (Knoxville, Tennessee); Yan Du (Knoxville, Tennessee) |
| ABSTRACT | Methods, systems, and computer readable mediums determining a system state of a power system using a convolutional neural network using a convolutional neural network are disclosed. One method includes converting power grid topology data corresponding to a power system into a power system matrix representation input and applying the power system matrix representation input to a plurality of convolutional layers of a deep convolutional neural network (CNN) structure in a sequential manner to generate one or more feature maps. The method further includes applying the one or more feature maps to a fully connected layer (FCL) operation for generating a respective one or more voltage vectors representing a system state of the power system. |
| FILED | Thursday, April 11, 2019 |
| APPL NO | 16/381934 |
| ART UNIT | 2839 — Printing/Measuring and Testing |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/027 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 13/0017 (20130101) H02J 2203/10 (20200101) H02J 2203/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544607 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Haoliang Sun (Madison, Wisconsin); Ronak R. Mehta (Madison, Wisconsin); Hao Zhou (Madison, Wisconsin); Vikas Singh (Madison, Wisconsin); Vivek Prabhakaran (Fitchburg, Wisconsin); Stirling C. Johnson (Fitchburg, Wisconsin) |
| ABSTRACT | A machine learning architecture employs two machine learning networks that are joined by a statistical model allowing the imposition of a predetermined statistical model family into a learning process in which the networks translate between and data types. For example, the statistical model may enforce a Gaussian conditional probability between the latent variables in the translation process. In one application, MRI images may be translated into PET images with reduced mode collapse, blurring, or other “averaging” type behaviors. |
| FILED | Monday, May 20, 2019 |
| APPL NO | 16/417192 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) G06N 3/0454 (20130101) G06N 7/005 (20130101) Original (OR) Class G06N 20/20 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544900 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Yen-Liang Lin (Redwood City, California); Xia Li (Lexington, Massachusetts); James Vradenburg Miller (Clifton Park, New York); Walter V Dixon, III (Duanesburg, New York) |
| ABSTRACT | According to some embodiments, a system, method and non-transitory computer-readable medium are provided comprising a 3D building modeling module; a memory for storing program instructions; a 3D building modeling processor, coupled to the memory, and in communication with the 3D building modeling module and operative to execute program instructions to: receive a region of interest; receive an image of the region of image from a data source; generate a surface model based on the received image including one or more buildings; generate a digital height model; decompose each building into a set of shapes; apply a correction process to the set of shapes; execute a primitive classification process to each shape; execute a fitting process to each classified shape; select a best fitting model; and generate a 3D model of each building. Numerous other aspects are provided. |
| FILED | Wednesday, July 22, 2020 |
| APPL NO | 16/935547 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 17/05 (20130101) Original (OR) Class G06T 17/10 (20130101) G06T 2207/10028 (20130101) G06T 2207/10032 (20130101) G06T 2207/20081 (20130101) G06T 2207/30184 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545173 | Provost et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Emily Mower Provost (Ann Arbor, Michigan); Melvin McInnis (Ann Arbor, Michigan); John Henry Gideon (Howell, Michigan); Katherine Anne Matton (Ann Arbor, Michigan); Soheil Khorram (Richardson, Texas) |
| ABSTRACT | A method of predicting a mood state of a user may include recording an audio sample via a microphone of a mobile computing device of the user based on the occurrence of an event, extracting a set of acoustic features from the audio sample, generating one or more emotion values by analyzing the set of acoustic features using a trained machine learning model, and determining the mood state of the user, based on the one or more emotion values. In some embodiments, the audio sample may be ambient audio recorded periodically, and/or call data of the user recorded during clinical calls or personal calls. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 16/556858 |
| ART UNIT | 2652 — Videophones and Telephonic Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 25/63 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545343 | Fan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Qi Hua Fan (Okemos, Michigan); Martin E. Toomajian (Brighton, Michigan) |
| ABSTRACT | A rotary plasma reactor system is provided. In another aspect, a plasma reactor is rotatable about a generally horizontal axis within a vacuum chamber. A further aspect employs a plasma reactor, a vacuum chamber, and an elongated electrode internally extending within a central area of the reactor. Yet another aspect employs a plasma reactor for use in activating, etching and/or coating tumbling workpiece material. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743091 |
| ART UNIT | 1716 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/509 (20130101) C23C 16/4417 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32458 (20130101) Original (OR) Class H01J 37/32669 (20130101) H01J 2237/18 (20130101) H01J 2237/332 (20130101) H01J 2237/334 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545563 | Makin, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of Western Michigan University (Kalamazoo, Michigan) |
| ASSIGNEE(S) | The Board of Trustees of Western Michigan University (Kalamazoo, Michigan) |
| INVENTOR(S) | Robert A. Makin, III (Kalamazoo, Michigan); Steven Michael Durbin (Kalamazoo, Michigan) |
| ABSTRACT | A process of fabricating semiconductor devices includes determining a correlation between band gap and long range order parameter for one or more stoichiometries. Semiconductor materials having a preselected (target) band gap can be fabricated by controlling process parameters to form a material having a stoichiometry and long range order parameter having the target band gap. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/011648 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/14 (20130101) H01L 29/66893 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545749 | Gómez-Diaz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Juan Sebastián Gómez-Diaz (Davis, California); Alejandro Álvarez-Melcón (Cartagena, Spain); Jiawei Zang (Beijing, China PRC) |
| ABSTRACT | A nonreciprocal phased-array antenna includes an array of resonant antennas a1, . . . , an. During transmission, an outbound signal having a frequency f0 and a phase shift φdi caused by propagation through a data network feeds into each resonant antenna ai. Each resonant antenna ai upconverts the outbound signal using a modulation signal having a frequency fm and a phase shift φmi caused by propagation through a modulation network to produce an upconverted radiated signal having a frequency f0+fm and a phase proportionate to φdi+φmi. During reception, an inbound signal of frequency f0+fm is received at each resonant antenna ai and is downconverted using the modulation signal to produce a downconverted signal having a frequency f0 and a phase proportionate to −φmi. After passing through the data network to the inbound port, the downconverted signal has a phase proportionate to φdi−φmi. |
| FILED | Thursday, July 16, 2020 |
| APPL NO | 16/931281 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11546077 | Bernstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Liane Sarah Beland Bernstein (Cambridge, Massachusetts); Alexander Sludds (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | Deep neural networks (DNNs) have become very popular in many areas, especially classification and prediction. However, as the number of neurons in the DNN increases to solve more complex problems, the DNN becomes limited by the latency and power consumption of existing hardware. A scalable, ultra-low latency photonic tensor processor can compute DNN layer outputs in a single shot. The processor includes free-space optics that perform passive optical copying and distribution of an input vector and integrated optoelectronics that implement passive weighting and the nonlinearity. An example of this processor classified the MNIST handwritten digit dataset (with an accuracy of 94%, which is close to the 96% ground truth accuracy). The processor can be scaled to perform near-exascale computing before hitting its fundamental throughput limit, which is set by the maximum optical bandwidth before significant loss of classification accuracy (determined experimentally). |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673268 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0675 (20130101) Transmission H04B 10/541 (20130101) H04B 10/614 (20130101) Multiplex Communication H04J 14/0224 (20130101) H04J 14/0234 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11546539 | Gruev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Viktor Gruev (Urbana, Illinois); Missael Garcia (Urbana, Illinois) |
| ABSTRACT | A polarization imager is provided that includes a plurality of CMOS photodetectors and a plurality of polarization filters. Each of the plurality of CMOS photodetectors has a photodiode that is configured to operate in forward bias mode. Further, each of the plurality of polarization filters is monolithically integrated with a corresponding one of the plurality of CMOS photodetectors. Each of the plurality of photodiodes exhibits a logarithmic response to a flux of incident photons. The polarization imager achieves a dynamic range of at least 100 decibels with a signal-to-noise ratio of at least 60 decibels. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 16/585711 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14625 (20130101) H01L 27/14643 (20130101) Pictorial Communication, e.g Television H04N 5/37455 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11546575 | Hua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Hong Hua (Tucson, Arizona); Hekun Huang (Tucson, Arizona) |
| ABSTRACT | A method for rendering light field images of a 3D scene in an HMD using an integral-imaging-based light field display. The method includes providing integral imaging (InI) optics including a microdisplay, the InI optics having a central depth plane (CDP) associated therewith; providing an eyepiece in optical communication with the InI optics, the eyepiece and the InI optics together providing InI-HMD optics; sampling the 3D scene using a simulated virtual array of cameras so that each camera captures a respective portion of the 3D scene to create a plurality of elemental images; and displaying the image data on the microdisplay. |
| FILED | Thursday, March 22, 2018 |
| APPL NO | 15/733600 |
| ART UNIT | 2419 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0172 (20130101) G02B 30/27 (20200101) G02B 2027/0123 (20130101) G02B 2027/0127 (20130101) G02B 2027/0134 (20130101) G02B 2027/0138 (20130101) Image Data Processing or Generation, in General G06T 15/20 (20130101) Pictorial Communication, e.g Television H04N 13/344 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11546987 | Johnson, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Alan T Johnson, Jr. (Philadelphia, Pennsylvania); Rajatesh R Gudibande (Philadelphia, Pennsylvania); Zhengqing John Qi (Albany, New York) |
| ABSTRACT | The present invention provides methods for fabricating graphene workpieces. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/212092 |
| ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/32 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/1606 (20130101) H01L 29/78684 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) Original (OR) Class H05K 1/0306 (20130101) H05K 3/06 (20130101) H05K 3/20 (20130101) H05K 3/125 (20130101) H05K 3/1216 (20130101) H05K 3/1275 (20130101) H05K 2201/0323 (20130101) H05K 2203/1338 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11541344 | Bischoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oakridge, Tennessee) |
| INVENTOR(S) | Brian L. Bischoff (Knoxville, Tennessee); James William Klett (Knoxville, Tennessee); Melanie Moses DeBusk (Knoxville, Tennessee) |
| ABSTRACT | An apparatus and system for separating a liquid from a mixed gas stream includes a porous graphite foam support comprising graphite foam with pores having a first pore size and a membrane support surface. A porous condensation membrane layer is provided on the membrane support surface, and interlocked with the pores of the graphite foam. The condensation membrane layer includes capillary condensation pores having a second pore size that is less than the first pore size. A mixed gas stream passageway is in fluid communication with the condensation membrane layer. A liquid collection assembly collects condensed liquid from the condensation pores and the graphite foam support pores. A gas inlet is provided for flowing the mixed gas stream into the mixed gas stream passageway. A gas outlet is provided for exhausting gas from the mixed gas stream passageway. A method for separating a liquid from a mixed gas stream is also disclosed. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/701279 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 5/009 (20130101) B01D 53/002 (20130101) Original (OR) Class B01D 2257/80 (20130101) B01D 2323/08 (20130101) B01D 2325/02 (20130101) Installations or Methods for Obtaining, Collecting, or Distributing Water E03B 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541350 | Jahnke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| ASSIGNEE(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| INVENTOR(S) | Fred C. Jahnke (Rye, New York); Matthew Lambrech (Sherman, Connecticut) |
| ABSTRACT | An EHS system includes a EHS cell having an anode, a cathode, and a cooling plate disposed proximate at least one of the anode or the cathode, the cooling plate configured to receive water and configured to output steam or a mixture of water and steam. The system further includes a liquid-vapor separator (LVS) configured to receive the steam or the mixture of water and steam from the cooling plate and to separate water and steam. The LVS is configured to output water to the cooling plate. |
| FILED | Friday, August 09, 2019 |
| APPL NO | 16/536535 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 53/263 (20130101) B01D 53/326 (20130101) Original (OR) Class B01D 2257/108 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11541372 | Paranthaman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee); UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee); UT-BATTELLE, LLC (Oakridge, Tennessee) |
| INVENTOR(S) | Mariappan Parans Paranthaman (Knoxville, Tennessee); Constantinos Tsouris (Oak Ridge, Tennessee); Samuel F. Evans (Knoxville, Tennessee); Marko R. Ivancevic (Lombard, Illinois) |
| ABSTRACT | An adsorbent for a target compound can include porous carbon particles having pores with a predominant pore size less than 10 nm, and magnetic nanoparticles (MNP) nucleated on the carbon surface and within the pores of carbon particles to provide a carbon magnetic nanoparticle adsorbent (C-MNA). A method for removing target compounds with an adsorbent, a system for removing contaminants from a liquid, and a method for adsorbing target compounds from a fluid are also disclosed. |
| FILED | Tuesday, May 05, 2020 |
| APPL NO | 16/867022 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 15/10 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) Original (OR) Class B01J 20/2805 (20130101) B01J 20/2808 (20130101) B01J 20/3231 (20130101) B01J 20/3416 (20130101) B01J 20/3475 (20130101) B01J 20/28004 (20130101) B01J 20/28009 (20130101) B01J 20/28016 (20130101) B01J 20/28059 (20130101) B01J 20/28061 (20130101) B01J 20/28064 (20130101) B01J 20/28066 (20130101) B01J 20/28083 (20130101) B01J 20/28085 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/01 (20130101) B03C 2201/18 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/66 (20130101) C02F 1/283 (20130101) C02F 2101/22 (20130101) C02F 2101/103 (20130101) C02F 2101/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542183 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | YuPo J. Lin (Naperville, Illinois); Seth W. Snyder (Lincolnwood, Illinois) |
| ABSTRACT | A resin-wafer electrodeionization (RW-EDI) apparatus for purifying water for coffee brewing comprises a cathode; an anode; and multiple porous solid resin wafer exchange units arranged in a stack between the cathode and the anode, and an air distributor adapted and arranged to aerate the water to be purified. Each unit comprises a monovalent cation exchange membrane (CEM), an anion exchange membrane (AEM), and an ion exchange resin wafer between the CEM and the AEM, which is in contact with, and in fluid flow connection with the CEM and AEM. Each resin wafer comprises a cation exchange resin and an anion exchange resin. The units are oriented with the CEM facing the cathode and the AEM facing the anode, with space between the units defining ion concentrate chambers. Bipolar ion exchange membranes separate the anode and cathode from their nearest resin wafer exchange units. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 16/697721 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 61/48 (20130101) B01D 61/50 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4695 (20130101) Original (OR) Class C02F 2201/4611 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542409 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Adaptive Surface Technologies, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Adaptive Surface Technologies, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Philseok Kim (Waltham, Massachusetts); Teluka Pasan Galhenage (Chestnut Hill, Massachusetts); Joseph Lomakin (Arlington, Massachusetts) |
| ABSTRACT | The present teachings generally provide curable polysiloxane compositions including a base resin including a surface active polymer. Articles of manufacture including the curable polysiloxane compositions and slippery coatings and materials also are provided. The compositions may be used to provide slippery, lubricious, or repellent materials and coatings and may provide anti-fouling function. The compositions can provide anti-fouling or foul-release function on open surfaces, internal surfaces, membranes; to provide pinning free or low contact angle hysteresis surfaces; to provide homogeneous interface to suppress nucleation; to provide a barrier layer such as anti-corrosion; to provide anti-stain, anti-smudge, anti-fingerprint, anti-soil function. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/183184 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/26 (20130101) B32B 7/12 (20130101) B32B 9/04 (20130101) B32B 25/04 (20130101) B32B 25/06 (20130101) B32B 25/10 (20130101) B32B 25/20 (20130101) B32B 27/06 (20130101) B32B 27/10 (20130101) B32B 27/12 (20130101) B32B 27/20 (20130101) B32B 27/30 (20130101) B32B 27/283 (20130101) B32B 27/285 (20130101) B32B 2250/03 (20130101) B32B 2250/04 (20130101) B32B 2255/02 (20130101) B32B 2255/12 (20130101) B32B 2255/26 (20130101) B32B 2270/00 (20130101) B32B 2307/41 (20130101) B32B 2307/412 (20130101) B32B 2307/414 (20130101) B32B 2307/538 (20130101) B32B 2307/714 (20130101) B32B 2307/728 (20130101) B32B 2307/732 (20130101) B32B 2307/746 (20130101) B32B 2307/752 (20130101) B32B 2307/7145 (20130101) B32B 2405/00 (20130101) B32B 2419/00 (20130101) B32B 2439/00 (20130101) B32B 2439/46 (20130101) B32B 2457/00 (20130101) B32B 2535/00 (20130101) B32B 2597/00 (20130101) B32B 2605/12 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/12 (20130101) C08G 77/16 (20130101) C08G 77/20 (20130101) C08G 77/28 (20130101) C08G 77/70 (20130101) Compositions of Macromolecular Compounds C08L 83/00 (20130101) C08L 83/00 (20130101) C08L 83/04 (20130101) C08L 83/04 (20130101) C08L 83/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1675 (20130101) C09D 183/04 (20130101) Original (OR) Class Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 107/50 (20130101) C10M 2229/0525 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2050/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542529 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CODEX DNA, INC. (San Diego, California) |
| ASSIGNEE(S) | Codex DNA, Inc. (San Diego, California) |
| INVENTOR(S) | Lei Young (Gaithersburg, Maryland); Hamilton O. Smith (San Diego, California); Daniel Glenn Gibson (Carlsbad, California) |
| ABSTRACT | The present invention relates, e.g., to in vitro method, using isolated protein reagents, for joining two double stranded (ds) DNA molecules of interest, wherein the distal region of the first DNA molecule and the proximal region of the second DNA molecule share a region of sequence identity, comprising contacting the two DNA molecules in a reaction mixture with (a) a non-processive 5′ exonuclease; (b) a single stranded DNA binding protein (SSB) which accelerates nucleic acid annealing; (c) a non strand-displacing DNA polymerase; and (d) a ligase, under conditions effective to join the two DNA molecules to form an intact double stranded DNA molecule, in which a single copy of the region of sequence identity is retained. The method allows the joining of a number of DNA fragments, in a predetermined order and orientation, without the use of restriction enzymes. |
| FILED | Monday, February 24, 2020 |
| APPL NO | 16/799424 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/93 (20130101) C12N 9/1252 (20130101) C12N 15/10 (20130101) C12N 15/64 (20130101) C12N 15/66 (20130101) C12N 15/902 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/62 (20130101) C12Q 1/62 (20130101) C12Q 1/686 (20130101) C12Q 1/6862 (20130101) C12Q 1/6862 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2522/101 (20130101) C12Q 2522/101 (20130101) C12Q 2522/101 (20130101) Enzymes C12Y 207/07007 (20130101) C12Y 301/11003 (20130101) C12Y 605/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542531 | Baker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Sarah Baker (Dublin, California); Joshuah K. Stolaroff (Oakland, California); Congwang Ye (Livermore, California) |
| ABSTRACT | According to one embodiment, a microcapsule for selective catalysis of gases, the microcapsule comprising: a polymeric shell permeable to one or more target gases; and at least one biocatalyst disposed in an interior of the polymeric shell. In more embodiments, methods of forming such microcapsules include: emulsifying at least one biocatalyst in a polymer precursor mixture; emulsifying the polymer precursor mixture in an aqueous carrier solution; crosslinking one or more polymer precursors of the polymer precursor mixture to form a plurality of microcapsules each independently comprising: a polymeric shell permeable to one or more target gases; and at least one biocatalyst disposed in an interior of the polymeric shell. In further embodiments, corresponding methods of using the inventive microcapsules for catalyzing one or more target gases using include: exposing a plurality of the biocatalytic microcapsules to the one or more target gases. |
| FILED | Friday, January 20, 2017 |
| APPL NO | 15/411337 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/003 (20130101) B01J 31/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) C12N 11/082 (20200101) C12N 11/084 (20200101) C12N 11/087 (20200101) C12N 11/089 (20200101) C12N 11/096 (20200101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542613 | Biener et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Monika M. Biener (San Leandro, California); Juergen Biener (San Leandro, California); Siwei Liang (Dublin, California); Zhen Qi (Tracy, California); Michael Stadermann (Pleasanton, California); Vedasri Vedharathinam (Fremont, California) |
| ABSTRACT | A flow-through electrolysis cell includes a hierarchical nanoporous metal cathode. A method of reducing CO2 includes flowing the CO2 through the hierarchical nanoporous metal cathode of the flow-through electrolysis cell. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 17/354664 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) C25B 3/26 (20210101) C25B 9/19 (20210101) C25B 11/031 (20210101) C25B 11/057 (20210101) Original (OR) Class C25B 11/061 (20210101) C25B 15/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11543474 | Schwindt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); QuSpin, Inc. (Louisville, Colorado) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Quspin, Inc. (Louisville, Colorado) |
| INVENTOR(S) | Peter Schwindt (Albuquerque, New Mexico); Yuan-Yu Jau (Albuquerque, New Mexico); Kaleb Lee Campbell (Albuquerque, New Mexico); Vishal Shah (Louisville, Colorado) |
| ABSTRACT | A method is provided for sensing a magnetic field in a magnetic gradiometer of the kind in which pump light and light constituting an optical carrier traverse first and second atomic vapor cells that contain host atoms and that are separated from each other by a known distance. According to such method, the host atoms are prepared in a coherent superposition of two quantum states that differ in energy by an amount that is sensitive to an ambient magnetic field. Modulation of the optical carrier in the respective cells gives rise to sidebands that interfere to generate a beat frequency indicative of the magnetic field gradient. The host atoms are prepared at least in a mode that allows measurement of ambient magnetic field components perpendicular to the axis of the pump light. In such mode, the host atoms are spin-polarized by pump light while subjected to a controlled magnetic field directed parallel to the pump beam, and then the controlled magnetic field is adiabatically extinguished. |
| FILED | Tuesday, July 20, 2021 |
| APPL NO | 17/380860 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Original (OR) Class G01R 33/1284 (20130101) Time-interval Measuring G04F 5/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544196 | SeyedzadehDelcheh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | SeyedMohammad SeyedzadehDelcheh (Bellevue, Washington); Shomit N. Das (Austin, Texas); Bradford Michael Beckmann (Redmond, Washington) |
| ABSTRACT | Systems, apparatuses, and methods for implementing a multi-tiered approach to cache compression are disclosed. A cache includes a cache controller, light compressor, and heavy compressor. The decision on which compressor to use for compressing cache lines is made based on certain resource availability such as cache capacity or memory bandwidth. This allows the cache to opportunistically use complex algorithms for compression while limiting the adverse effects of high decompression latency on system performance. To address the above issue, the proposed design takes advantage of the heavy compressors for effectively reducing memory bandwidth in high bandwidth memory (HBM) interfaces as long as they do not sacrifice system performance. Accordingly, the cache combines light and heavy compressors with a decision-making unit to achieve reduced off-chip memory traffic without sacrificing system performance. |
| FILED | Monday, December 23, 2019 |
| APPL NO | 16/725971 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3037 (20130101) G06F 12/0246 (20130101) G06F 12/0871 (20130101) Original (OR) Class G06F 12/0897 (20130101) G06F 2212/401 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544426 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Honggang Wang (Clifton Park, New York); Weizhong Yan (Clifton Park, New York); Kaveri Mahapatra (State College, Pennsylvania) |
| ABSTRACT | A system for enhanced sequential power system model calibration is provided. The system is programmed to store a model of a device. The model includes a plurality of parameters. The system is also programmed to receive a plurality of events associated with the device, receive a first set of calibration values for the plurality of parameters, generate a plurality of sets of calibration values for the plurality of parameters, for each of the plurality of sets of calibration values, analyze a first event of the plurality of events using a corresponding set of calibration values to generate a plurality of updated sets of calibration values, analyze the plurality of updated sets of calibration values to determine a current updated set of calibration values, and update the model to include the current updated set of calibration values. |
| FILED | Tuesday, October 15, 2019 |
| APPL NO | 16/601732 |
| ART UNIT | 2146 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 7/58 (20130101) G06F 17/14 (20130101) G06F 30/18 (20200101) G06F 30/20 (20200101) Original (OR) Class G06F 2111/02 (20200101) G06F 2111/10 (20200101) G06F 2113/04 (20200101) G06F 2119/06 (20200101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/06 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/003 (20200101) H02J 3/008 (20130101) H02J 2203/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544916 | Al Rashdan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Fall, Indonesia); University of Idaho (Moscow, Idaho) |
| INVENTOR(S) | Ahmad Y. Al Rashdan (Ammon, Idaho); Roger Lew (Moscow, Idaho); Michael L. Wheeler (Greenwood, Indiana); Gregory D. Lancaster (Idaho Falls, Idaho); Troy C. Unruh (Idaho Falls, Idaho) |
| ABSTRACT | Computing devices and methods for reading gauges are disclosed. A gauge reading method includes capturing image data corresponding to a captured image of one or more gauges, detecting one or more gauges in the captured image, cropping a detected gauge in the captured image to provide a use image including the detected gauge, and classifying the detected gauge to correlate the detected gauge with a template image. The gauge reading method also includes attempting to perform feature detection rectification on the use image to produce a rectified image of the detected gauge, performing template matching rectification on the use image to produce the rectified image responsive to a failure to perform the feature detection rectification, and estimating a gauge reading responsive to the rectified image. A computing device may implement at least a portion of a gauge reading method. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097452 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 7/1417 (20130101) Image Data Processing or Generation, in General G06T 3/60 (20130101) G06T 7/74 (20170101) G06T 2207/10032 (20130101) Image or Video Recognition or Understanding G06V 10/44 (20220101) G06V 10/60 (20220101) G06V 10/751 (20220101) Original (OR) Class G06V 20/13 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545297 | Dede et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Toyota Motor Engineering and Manufacturing North America, Inc. (Plano, Texas); University of Colorado Boulder (Boulder, Colorado) |
| ASSIGNEE(S) | TOYOTA MOTOR ENGINEERING and MANUFACTURING NORTH AMERICA, INC. (Plano, Texas); UNIVERSITY OF COLORADO BOULDER (Boulder, Colorado) |
| INVENTOR(S) | Ercan Dede (Ann Arbor, Michigan); Yucheng Gao (Boulder, Colorado); Vivek Sankaranarayanan (Boulder, Colorado); Aritra Ghosh (Boulder, Colorado); Robert Erickson (Boulder, Colorado); Dragan Maksimovic (Boulder, Colorado) |
| ABSTRACT | Embodiments of the disclosure relate to apparatuses for enhanced thermal management of an inductor assembly using functionally-graded thermal vias for heat flow control in the windings of the inductor. In one embodiment, a PCB for an inductor assembly includes a top surface and a bottom surface. Two or more electrically-conductive layers are embedded within the PCB and stacked vertically between the top surface and the bottom surface. The two or more electrically-conductive layers are electrically connected to form an inductor winding. A plurality of thermal vias thermally connects each of the two or more electrically-conductive layers to a cold plate thermally connected to the bottom surface. A number of thermal vias thermally connecting each electrically-conductive layer to the cold plate is directly proportional to a predetermined rate of heat dissipation from the electrically-conductive layer. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/692653 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/24 (20130101) H01F 27/2804 (20130101) H01F 27/2876 (20130101) Original (OR) Class H01F 2027/2809 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/115 (20130101) H05K 1/165 (20130101) H05K 1/0206 (20130101) H05K 2201/066 (20130101) H05K 2201/09609 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545675 | Zeng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Xiaoqiao Zeng (Naperville, Illinois); Khalil Amine (Oakbrook, Illinois); Jun Lu (Naperville, Illinois); Yuanyuan Guo (Westmont, Illinois) |
| ABSTRACT | A metal-air battery includes an anode; a low-dimensional catalyst cathode; and an electrolyte; wherein: the low-dimensional catalyst cathode comprises a functional metal layer on a carbon support overcoated with a catalyst layer; the electrolyte comprises an aprotic solvent that is an ether-based solvent, a fluorinated ether-based solvent, an oligo (ethylene oxide) solvent, or a mixture of any two or more thereof; and the electrolyte is free of carbonate solvents. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988279 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/926 (20130101) Original (OR) Class H01M 4/8871 (20130101) H01M 12/02 (20130101) H01M 12/08 (20130101) H01M 2004/8689 (20130101) H01M 2300/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545723 | Spoerke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Erik David Spoerke (Albuquerque, New Mexico); Martha Gross (Albuquerque, New Mexico); Stephen Percival (Albuquerque, New Mexico); Mark A. Rodriguez (Albuquerque, New Mexico); Leo J. Small (Albuquerque, New Mexico) |
| ABSTRACT | The present invention is directed to the modification of sodium electrochemical interfaces to improve performance of NaSICON-type ceramics in a variety of electrochemical applications. Enhanced mating of the separator-sodium interface by means of engineered coatings or other surface modifications results in lower interfacial resistance and higher performance at increased current densities, enabling the effective operation of molten sodium batteries and other electrochemical technologies at low and high temperatures. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/104306 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/054 (20130101) H01M 50/434 (20210101) H01M 50/449 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545724 | Frischmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SEPION TECHNOLOGIES, INC. (Emeryville, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Sepion Technologies. Inc. (Emeryville, California) |
| INVENTOR(S) | Peter David Frischmann (Berkeley, California); Brett Anthony Helms (Oakland, California) |
| ABSTRACT | A composite membrane with nanostructured inorganic and organic phases is applied as an ion-selective layer to prove processability, prevent dendrite shorting, and increase power output of lithium-metal anodes through better Li-ion conductivity. Nanoconfinement, as opposed to macroscale confinement, is known to dramatically alter the properties of bulk materials. Control over a ceramic's size, shape, and properties is achieved with polymer templates. This is a new composition of matter and unique approach to composite membrane design. |
| FILED | Thursday, December 07, 2017 |
| APPL NO | 16/465013 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 10/0525 (20130101) H01M 10/0569 (20130101) H01M 50/46 (20210101) Original (OR) Class H01M 50/446 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545815 | Lentine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Anthony L. Lentine (Albuquerque, New Mexico); Grant Biedermann (Albuquerque, New Mexico); Michael Gehl (Albuquerque, New Mexico); Christopher DeRose (Victor, New York); Jongmin Lee (Albuquerque, New Mexico); Kevin Michael Fortier (Milwaukie, Oregon) |
| ABSTRACT | A compact laser source and a single sideband modulator used therein is disclosed. The compact laser source includes a seed laser and one or more channels, with each channel generating one or more output laser beams having corresponding different wavelengths. The compact laser source can be formed in whole or in part on a single optical motherboard to thereby minimize space and power requirements. By employing the disclosed single sideband modulator, harmonics in the generated output laser beams can be minimized. The compact laser source finds application in an atom interferometer (AI) system, which may be used to measure gravity, acceleration, or rotation of the AI system. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 16/831350 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/106 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/37 (20130101) G02F 1/3551 (20130101) G02F 2203/48 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0078 (20130101) H01S 3/0085 (20130101) H01S 3/0092 (20130101) H01S 5/34 (20130101) H01S 5/041 (20130101) H01S 5/0683 (20130101) H01S 5/5045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545929 | Scipione et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Donald S. Scipione (Cleveland Heights, Ohio); Rob Martens (Cleveland, Ohio) |
| ASSIGNEE(S) | UNITED STATES DEPARTMENT OF ENERGY (Washington, District of Columbia) |
| INVENTOR(S) | Donald S. Scipione (Cleveland Heights, Ohio); Rob Martens (Cleveland, Ohio) |
| ABSTRACT | A method of installing on a horizontal or near-horizontal support surface a solar panel array including multiple solar panels may include, at the deployment site, fabricating from metal coil stock longitudinally continuous rack channels each having upstanding legs of different heights, locating the channels in parallel rows with a spacing determined by a width of the solar panels with interior spaces of the channels facing upwardly, weighing the channels down on the support surface by placing ballast in the channel spaces, and positioning the solar panels each with an edge supported by a high leg of one channel of the channels and an opposite edge supported by a low leg of an adjacent channel of the channels. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/233388 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 30/10 (20141201) Original (OR) Class H02S 40/34 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11542291 | Ziegler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation, University Park (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Gregory Ray Ziegler (State College, Pennsylvania); Joshua David Lambert (State College, Pennsylvania); Emmanuel Hatzakis (Columbus, Ohio); Eugene P. Mazzola (Vienna, Virginia) |
| ABSTRACT | The present invention provides compounds isolated from avocado seeds for use as a natural colorant in edible materials. The compounds of the invention are useful for coloring edible materials red, orange, or yellow. The invention also provides compositions and methods for coloring edible materials to a desired color such as red, orange, or yellow. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 16/512445 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 59/82 (20130101) C07C 2603/30 (20170501) Heterocyclic Compounds C07D 305/10 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/24 (20130101) Original (OR) Class C07H 15/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP34879 | Grauke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Larry J. Grauke (College Station, Texas); Tommy E. Thompson (College Station, Texas) |
| ABSTRACT | A new and distinct variety of pecan tree, denominated ‘Zuni’, having large nuts in medium-sized clusters, well-filled cream-colored kernels, medium precocity, and high resistance to scab fungus (Venturia effusa). |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 17/668127 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/00 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP34880 | Hardigan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Michael A. Hardigan (Corvallis, Oregon); Chad E. Finn (Corvallis, Oregon) |
| ABSTRACT | A new and distinct blackberry cultivar that originated from seed produced from a cross between the thornless semi-erect maternal blackberry plant ‘Eclipse’ and the thorny erect paternal blackberry plant ORUS 3681-1, the latter of which introduces genetics from cultivated and wild Rubus germplasm from the southeastern U.S. This new blackberry cultivar can be distinguished by its high plant vigor, exceptional yields of small-to-medium sized berries with high gloss, low defects, excellent flavor and fruit quality, and high heat tolerance. The berries are well suited for fresh eating, with good sweetness, aroma, and gloss when picked firm. The new and distinct blackberry variety has fruit that are borne on vigorous canes which contain the ‘Merton Thornless’ source of genetic thornlessness. |
| FILED | Thursday, March 17, 2022 |
| APPL NO | 17/697900 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/203 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11542042 | Daniels et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Keir Daniels (New York, New York); Zachary Switzer (Washington, District of Columbia); Dimitris Kiaoulias (Washington, District of Columbia); Michael Keidar (Baltimore, Maryland) |
| ABSTRACT | A matrix thruster that may be used to reposition and/or stabilize a CubeSAT satellite. The matrix thruster includes a conductive plate with an opening, a plurality of wires within the opening, a power supply electrically connected to the conductive plate or each of the plurality of wires via an inductor, and an electrical switch. The electrical switch creates a current change that creates an electric potential spike across the inductor. The electric potential spike across the inductor initiates an arc discharge between one of the wires and the conductive plate, which forms plasma that ejects cathode particles from the matrix thruster. Using multiple wires (e.g., four titanium wires) extends the lifetime of the thruster, as each wire restores an inter-electrode film needed for the other wires to continue generating plasma. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/021019 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/105 (20130101) B64G 1/405 (20130101) Original (OR) Class B64G 1/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542043 | Murphey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Opterus Research and Development, Inc. (Fort Collins, Colorado) |
| ASSIGNEE(S) | Opterus Research and Development, Inc. (Fort Collins, Colorado) |
| INVENTOR(S) | Thomas W. Murphey (Fort Collins, Colorado); Levi Nicholson (Fort Collins, Colorado); Michael Folkers (Fort Collins, Colorado); Kyle Egan (Fort Collins, Colorado); Erik Pranckh (Fort Collins, Colorado) |
| ABSTRACT | A trussed collapsible tubular mast includes a deformable beam having an extended state, a flattened state, and a rolled state, where a stiffness and strength of the deformable beam in the extended state is greater than a different stiffness and a different strength of the deformable beam in the flattened state. At least one collapsible tubular mast wall has a plurality of truss members of a first material having a first material thickness. At least one truss member is disposed substantially perpendicular to a longitudinal axis of the trussed collapsible tubular mast. Disposed between the truss members is a wall area of a second material thickness less thick than the first material thickness. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/305740 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/222 (20130101) B64G 1/407 (20130101) B64G 1/443 (20130101) B64G 99/00 (20220801) Original (OR) Class Structural Elements; Building Materials E04C 3/005 (20130101) E04C 3/09 (20130101) E04C 3/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11542486 | Georgiou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | George Georgiou (Austin, Texas); Everett Stone (Austin, Texas); John Blazeck (Austin, Texas) |
| ABSTRACT | Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids. |
| FILED | Thursday, March 02, 2017 |
| APPL NO | 16/081492 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/46 (20130101) A61K 39/3955 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Original (OR) Class C12N 9/96 (20130101) Enzymes C12Y 307/01003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11544657 | MacAdam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | State of Ohio, Department of Transportation (Columbus, Ohio) |
| ASSIGNEE(S) | State of Ohio, Department of Transportation (Columbus, Ohio) |
| INVENTOR(S) | John A. MacAdam (Columbus, Ohio); David L. Holstein (Xenia, Ohio); Thomas M. Lyden (Hilliard, Ohio); Sonja R. Simpson (Pickerington, Ohio); Scott E. Lucas (Ashley, Ohio) |
| ABSTRACT | A system and method for analyzing the effectiveness of road maintenance efforts within a district is provided. Data obtained from roadway weather information stations and a traffic data monitoring system is gathered to determine when weather events begin and end based upon weather conditions and traffic information. The effectiveness of roadway maintenance efforts after the end of such weather event is determined. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/160645 |
| ART UNIT | 3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06398 (20130101) Original (OR) Class Traffic Control Systems G08G 1/00 (20130101) G08G 1/0104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11543333 | Cho |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Inho Cho (Egg Harbor Township, New Jersey) |
| ABSTRACT | In an example, a thermal extraction apparatus includes: a housing having a gas inlet and a gas outlet to receive a gas flow through the housing from the gas inlet to the gas outlet, and a side opening to receive a sample collector, having a sample collector adsorbent containing a vapor sample, into a sample collector location; a pump to generate the gas flow; a heater to heat the sample collector adsorbent of the sample collector to a temperature sufficient to release the vapor sample; a thermal desorption (TD) tube connected with the gas outlet of the housing to receive the gas flow downstream of the sample collector and collect the vapor sample released from the sample collector adsorbent of the sample collector; and a cooling member in heat exchange with the TD tube to cool the TD tube. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 17/556543 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 1/2214 (20130101) Original (OR) Class G01N 1/2247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11544657 | MacAdam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | State of Ohio, Department of Transportation (Columbus, Ohio) |
| ASSIGNEE(S) | State of Ohio, Department of Transportation (Columbus, Ohio) |
| INVENTOR(S) | John A. MacAdam (Columbus, Ohio); David L. Holstein (Xenia, Ohio); Thomas M. Lyden (Hilliard, Ohio); Sonja R. Simpson (Pickerington, Ohio); Scott E. Lucas (Ashley, Ohio) |
| ABSTRACT | A system and method for analyzing the effectiveness of road maintenance efforts within a district is provided. Data obtained from roadway weather information stations and a traffic data monitoring system is gathered to determine when weather events begin and end based upon weather conditions and traffic information. The effectiveness of roadway maintenance efforts after the end of such weather event is determined. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/160645 |
| ART UNIT | 3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06398 (20130101) Original (OR) Class Traffic Control Systems G08G 1/00 (20130101) G08G 1/0104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 11544900 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Yen-Liang Lin (Redwood City, California); Xia Li (Lexington, Massachusetts); James Vradenburg Miller (Clifton Park, New York); Walter V Dixon, III (Duanesburg, New York) |
| ABSTRACT | According to some embodiments, a system, method and non-transitory computer-readable medium are provided comprising a 3D building modeling module; a memory for storing program instructions; a 3D building modeling processor, coupled to the memory, and in communication with the 3D building modeling module and operative to execute program instructions to: receive a region of interest; receive an image of the region of image from a data source; generate a surface model based on the received image including one or more buildings; generate a digital height model; decompose each building into a set of shapes; apply a correction process to the set of shapes; execute a primitive classification process to each shape; execute a fitting process to each classified shape; select a best fitting model; and generate a 3D model of each building. Numerous other aspects are provided. |
| FILED | Wednesday, July 22, 2020 |
| APPL NO | 16/935547 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 17/05 (20130101) Original (OR) Class G06T 17/10 (20130101) G06T 2207/10028 (20130101) G06T 2207/10032 (20130101) G06T 2207/20081 (20130101) G06T 2207/30184 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11544900 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| INVENTOR(S) | Yen-Liang Lin (Redwood City, California); Xia Li (Lexington, Massachusetts); James Vradenburg Miller (Clifton Park, New York); Walter V Dixon, III (Duanesburg, New York) |
| ABSTRACT | According to some embodiments, a system, method and non-transitory computer-readable medium are provided comprising a 3D building modeling module; a memory for storing program instructions; a 3D building modeling processor, coupled to the memory, and in communication with the 3D building modeling module and operative to execute program instructions to: receive a region of interest; receive an image of the region of image from a data source; generate a surface model based on the received image including one or more buildings; generate a digital height model; decompose each building into a set of shapes; apply a correction process to the set of shapes; execute a primitive classification process to each shape; execute a fitting process to each classified shape; select a best fitting model; and generate a 3D model of each building. Numerous other aspects are provided. |
| FILED | Wednesday, July 22, 2020 |
| APPL NO | 16/935547 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 17/05 (20130101) Original (OR) Class G06T 17/10 (20130101) G06T 2207/10028 (20130101) G06T 2207/10032 (20130101) G06T 2207/20081 (20130101) G06T 2207/30184 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11542319 | Leighton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Crystal Bioscience Inc. (San Diego, California) |
| ASSIGNEE(S) | CRYSTAL BIOSCIENCE INC. (Emeryville, California) |
| INVENTOR(S) | Philip A. Leighton (San Francisco, California); William Don Harriman (Alameda, California); Robert Etches (Oakland, California) |
| ABSTRACT | A transgenic chicken comprising an inactivated heavy immunoglobulin gene and/or inactivated light chain immunoglobulin gene is provided, as well as cells and targeting vectors for making the same. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875644 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2227/30 (20130101) Peptides C07K 16/00 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/24 (20130101) C07K 2317/51 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11543254 | Turner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Alison Frankowski Turner (Arlington, Virginia); Marc D. McCrery (Arlington, Virginia); James J. Boldt (Leesburg, Virginia) |
| ABSTRACT | A system and method of augmenting a delivery route. The method comprises receiving first location information from a first position device and receiving second location information from a second position device. The method further comprises storing the first and second location information in a memory structure and determining, based on at least one of the first and second information, a time and a location for each of a plurality of stops. The method also comprises reconciling the determined time and location of each of the plurality of stops with a stored route comprising a plurality of stored stops, the stored stops having a stored location and a stored time associated therewith and estimating a plurality of transition times between pairs of the plurality of stops. The method further also comprises constructing an updated timeline based on the plurality of stored stops, the plurality of determined stops, and the plurality of transition times and updating the delivery route based on the constructed timeline. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 16/818982 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 50/045 (20130101) B60W 2050/046 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3492 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/047 (20130101) G06Q 10/08355 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11542491 | Jo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (Gyeongsangnam-do, South Korea) |
| ASSIGNEE(S) | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (Gyeongsangnam-Do, South Korea) |
| INVENTOR(S) | Byung-hoon Jo (Gyeongsangnam-do, South Korea) |
| ABSTRACT | A fusion tag according to an embodiment of the present invention may increase the water solubility and expression level of a target protein. As the water solubility and expression level of a target protein in host cell can be increased by a recombinant vector including the fusion tag, the fusion tag can be advantageously used in industry. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/772890 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Original (OR) Class Enzymes C12Y 402/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11542826 | Wolfer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Scott Francis Wolfer (Cincinnati, Ohio); Richard Alan Wesling (Cincinnati, Ohio) |
| ABSTRACT | A labyrinth seal including: an annular seal body having an inner wall and an outer wall spaced apart from one another by an annulus; a nested dampener system disposed along the outer wall, the nested dampener system including: a first dampening element; and a second dampening element, wherein opposite axial ends of the nested dampener system are defined by the first dampening element, and wherein the second dampening element is disposed outside of at least a portion of the first dampening element in a radial direction. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/205059 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/02 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/55 (20130101) Pistons; Cylinders; Sealings F16J 15/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11545288 | Strand |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joel D. Strand (Ellicott City, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Joel D. Strand (Ellicott City, Maryland) |
| ABSTRACT | One example includes a superconducting current control system. The system includes an inductive coupler comprising a load inductor and a control inductor. The inductive coupler can be configured to inductively provide a control current from the control inductor to a superconducting circuit device based on a load current being provided through the load inductor. The system also includes a current control element comprising a superconducting quantum interference device (SQUID) array comprising a plurality of SQUIDs. The current control element can be coupled to the inductive coupler to control an amplitude of the load current through the load inductor, and thus to control an amplitude of the control current to the superconducting circuit device. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 16/849595 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/008 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/18 (20130101) H01L 39/025 (20130101) H01L 39/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11546010 | Beglin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas Wayne Beglin (Ellicott City, Maryland); Farooq Ul Amin (Cary, North Carolina) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Thomas Wayne Beglin (Ellicott City, Maryland); Farooq Ul Amin (Cary, North Carolina) |
| ABSTRACT | One example includes a switch system. The system includes a first signal port and a second signal port. The system also includes a first switching path arranged between the first and second signal ports. The first switching path includes at least one first switch and at least one of the at least one first switch being configured as a high-speed switching device. The system further includes a second switching path arranged between the first and second signal ports in parallel with the first switching path. The second switching path includes at least one second switch and at least one of the at least one second switch being configured as a high-performance switching device. |
| FILED | Tuesday, February 16, 2021 |
| APPL NO | 17/176957 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 1/006 (20130101) H04B 1/44 (20130101) Original (OR) Class H04B 1/401 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, January 03, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230103.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page