FedInvent™ Patents
Patent Details for Tuesday, January 31, 2023
This page was updated on Wednesday, February 01, 2023 at 12:43 PM GMT
Department of Health and Human Services (HHS)
US 11564607 | Berenfeld et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Omer Berenfeld (Ann Arbor, Michigan); Hakan Oral (Ann Arbor, Michigan) |
ABSTRACT | A multiple-point basket-type or crown-shaped catheter device provides simultaneously mapping over a three-dimensional (3D) region of a subject, such as, one or more chambers of a subject's heart. The catheter device may include a series of splines each having a wave-like profile formed of a periodic series of peaks and troughs, with electrodes located at the peaks and troughs for mapping purposes. |
FILED | Wednesday, April 06, 2016 |
APPL NO | 15/092335 |
ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/068 (20130101) A61B 5/287 (20210101) Original (OR) Class A61B 5/361 (20210101) A61B 5/6858 (20130101) A61B 5/7253 (20130101) A61B 18/1492 (20130101) A61B 34/20 (20160201) A61B 2017/00044 (20130101) A61B 2017/00048 (20130101) A61B 2017/00053 (20130101) A61B 2018/0016 (20130101) A61B 2018/00267 (20130101) A61B 2018/00351 (20130101) A61B 2018/00839 (20130101) A61B 2018/00892 (20130101) A61B 2018/00898 (20130101) A61B 2562/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564608 | Weingärtner et al. |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Sebastian Weingärtner (Stanford, California); Tirin Moore (Stanford, California) |
ABSTRACT | Systems and methods for performing online spike recovery from multi-channel electrophysiological recordings in accordance with various embodiments of the invention are described. One embodiment of a method of performing online spike recovery from multi-channel electrophysiological recordings includes: determining a set of waveform templates; continuously obtaining multi-channel electrophysiological recordings using a multi-channel electrode; and automatically performing online spike recovery from the multi-channel electrophysiological recordings using a processing system that performs a method for sparse signal recovery that continuously adjusts a processing buffer size based upon newly obtained multi-channel electrophysiological recordings. |
FILED | Monday, March 09, 2020 |
APPL NO | 16/813579 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/291 (20210101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564615 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trastees of the Leland (Stanford, California); Stanford Junior University (Stanford, California) |
INVENTOR(S) | Jin Hyung Lee (Stanford, California); David Bernal-Casas (East Palo Alto, California) |
ABSTRACT | Methods and systems for analyzing brain functional activity data are provided. Also provided are systems that find use in performing the present methods. |
FILED | Monday, January 30, 2017 |
APPL NO | 16/072476 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/245 (20210101) A61B 5/246 (20210101) A61B 5/369 (20210101) A61B 5/377 (20210101) Original (OR) Class A61B 5/4064 (20130101) A61B 2576/026 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0622 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/50 (20180101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564619 | Lotz et al. |
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APPLICANT(S) | ACLARION, INC. (San Mateo, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | ACLARION, INC. (San Mateo, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Jeffrey C. Lotz (Oakland, California); James Clayton Peacock, III (Redwood City, California); David S. Bradford (Sausalito, California); Stefan Dudli (Bern, Switzerland); Sergey G. Magnitsky (Oakland, California) |
ABSTRACT | An MR Spectroscopy (MRS) system and approach is provided for measuring spectral information corresponding with propionic acid (PA), either alone or in combination with other measurements corresponding with other chemicals, to diagnose and/or monitor at least one of bacterial infection, such as associated with P. acnes, or conditions related thereto such as nociceptive pain associated with tissue acidity. An interfacing DDD-MRS signal processor receives output signals to produce a post-processed spectrum, with spectral regions corresponding with certain chemicals, including PA, then measured as biomarkers. A diagnostic processor derives a diagnostic value for each disc, and performs certain normalizations, based upon ratios of the spectral regions related to chemicals implicated in degenerative painful tissue pathology, such as PA and hypoxia markers of lactic acid (LA) and alanine (AL), and structural chemicals of proteoglycan (PG) and collagen or carbohydrate (CA). |
FILED | Tuesday, December 18, 2018 |
APPL NO | 16/224590 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/412 (20130101) A61B 5/4514 (20130101) Original (OR) Class A61B 5/4566 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) G01R 33/465 (20130101) G01R 33/483 (20130101) G01R 33/485 (20130101) G01R 33/4828 (20130101) G01R 33/5608 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564639 | Tichauer et al. |
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APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
INVENTOR(S) | Kenneth Tichauer (Chicago, Illinois); Robert W. Holt (Lebanon, New Hampshire); Frederic Leblond (Montreal, Canada); Pablo Valdes (Hanover, New Hampshire); Brian W. Pogue (Hanover, New Hampshire); Keith D. Paulsen (Hanover, New Hampshire); David W. Roberts (Lyme, New Hampshire) |
ABSTRACT | A method of generating corrected fluorescence data of concentrations of a targeted fluorophore in tissue of a subject includes administering first and second fluorescent contrast agents to the subject, the first contrast agent targeted to tissue of interest, the second agent untargeted. The tissue is illuminated with light of a first stimulus wavelength and first data is acquired at an appropriate emissions wavelength; the tissue is illuminated at a second stimulus wavelength and second data is acquired at a second emissions wavelength associated with the second agent, the first and second emissions wavelength differ. Difference data is generated by subtracting the second data from the first data. A system provides for stimulus and capture at multiple wavelengths, with image storage memory and subtraction code, to perform the method. Corrected data may form an fluorescence image, or is used to generate fluorescence tomographic images. |
FILED | Thursday, February 13, 2014 |
APPL NO | 14/767836 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/0062 (20130101) A61B 5/0071 (20130101) A61B 5/7278 (20130101) Original (OR) Class A61B 2576/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 49/0058 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564667 | Dominguez-Bello |
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APPLICANT(S) | New York University (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Maria Gloria Dominguez-Bello (New York, New York) |
ABSTRACT | The invention relates to methods and compositions for restoring normal microbiota in pre-term newborns or newborns delivered by Cesarean section and methods for preventing or ameliorating diseases associated with delivery by Cesarean section or pre-term birth comprising administering to said newborns at the time of birth or shortly thereafter an effective amount of a vaginal microbiota inoculum obtained from the newborn's mother or a donor or an effective amount of a probiotic composition. The invention also relates to a device for collecting maternal vaginal microbiota from the vaginal canal of a patient. The device can have a housing forming a cavity, an absorbent material removable disposed within the cavity, and a deployment element disposed in the housing and movable along a length of the housing. The movement of the deployment element can displace the absorbent material out of the cavity and in to the vaginal canal. |
FILED | Tuesday, December 27, 2016 |
APPL NO | 16/064110 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0045 (20130101) Original (OR) Class A61B 2010/0074 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/742 (20130101) A61K 35/745 (20130101) A61K 35/747 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564673 | Perry et al. |
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FUNDED BY |
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APPLICANT(S) | TRICOL BIOMEDICAL, INC. (Portland, Oregon); OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
ASSIGNEE(S) | Tricol Biomedical, Inc. (Portland, Oregon); Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | Kenneth E. Perry (Bainbridge Island, Washington); Kenneth P. Perry (Bainbridge Island, Washington); Hua Xie (Portland, Oregon); Brintha Enestvedt (Portland, Oregon); Simon J. McCarthy (Portland, Oregon) |
ABSTRACT | The present disclosure relates to a gastrointestinal delivery device of a dressing, where the delivery device is capable of fitting through a narrow channel before expanding and applying the dressing. The gastrointestinal delivery device may be used in all gastrointestinal bleeding applications and can be used with a biocompatible, foldable, thin profile, chitosan dressing. Various aspects of the device and its uses are provided herein. |
FILED | Friday, December 28, 2018 |
APPL NO | 16/958304 |
ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0057 (20130101) Original (OR) Class A61B 17/00234 (20130101) A61B 2017/0034 (20130101) A61B 2017/00597 (20130101) A61B 2017/00623 (20130101) A61B 2017/00818 (20130101) A61B 2017/00951 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564701 | Pak et al. |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Nikita Pak (Allston, Massachusetts); Justin P. Kinney (Quincy, Massachusetts); Edward S. Boyden (Chestnut Hill, Massachusetts) |
ABSTRACT | An automated craniotomy opening apparatus includes a drilling apparatus with a drilling tip, at least one drilling apparatus positioning device, a detection device, and a computer processor that automatically controls the drilling apparatus, the positioning device, and the detection device. A method for automated opening of craniotomies includes, under automatic control of a computer processor, drilling into a skull for a predetermined distance and determining when there is a conductance drop near the drilling tip that indicates skull breakthrough. If the conductance is not below a predetermined threshold, drilling continues iteratively manner until conductance is below the threshold. A craniotomy pattern may be predetermined and automatically drilled under control of the processor. A cranial window may be created by drilling along a path that interpolates between holes to form the circumference of the window. Determining conductance may include use of an impedance detection circuit. |
FILED | Tuesday, November 03, 2020 |
APPL NO | 17/088494 |
ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1695 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 34/32 (20160201) A61B 90/10 (20160201) A61B 2017/00026 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564742 | Yang et al. |
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APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
INVENTOR(S) | Chen Yang (Newton, Massachusetts); Ji-Xin Cheng (Newton, Massachusetts); Nan Zheng (Allston, Massachusetts); Yueming Li (Brighton, Massachusetts); Ying Jiang (Brighton, Massachusetts); Lu Lan (Allston, Massachusetts); Carolyn Marar (Brighton, Massachusetts) |
ABSTRACT | A system for neuromodulation includes a split-ring resonator (SRR) comprising a resonance circuit, the SRR being implantable in a cranial target site and a source of microwave signals, wherein the microwave signals are deliverable wirelessly to couple with the SRR to produce a localized electrical field, wherein the localized electrical field inhibits one or more neurons at the cranial target site with submillimeter spatial precision. |
FILED | Thursday, May 05, 2022 |
APPL NO | 17/737710 |
ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/1815 (20130101) Original (OR) Class A61B 2018/183 (20130101) A61B 2018/1869 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/082 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564757 | Tsao et al. |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Tsu-Chin Tsao (Los Angeles, California); Cheng-Wei Chen (Los Angeles, California); Yu-Hsiu Lee (Los Angeles, California); Matthew Gerber (Los Angeles, California); Jean-Pierre Hubschman (Los Angeles, California) |
ABSTRACT | A robotic surgery system includes: (1) a positioning stage and (2) at least one manipulator arm mounted to the positioning stage, wherein the manipulator arm includes a track and a tool carriage moveably mounted to the track, and the tool carriage includes a base and a pair of light emitting devices mounted to the base. |
FILED | Monday, February 26, 2018 |
APPL NO | 16/487074 |
ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/20 (20160201) A61B 34/30 (20160201) Original (OR) Class A61B 90/13 (20160201) A61B 90/14 (20160201) A61B 90/50 (20160201) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/00736 (20130101) A61F 2009/0035 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564889 | Cheng et al. |
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APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
INVENTOR(S) | Ke Cheng (Raleigh, North Carolina); Junnan Tang (Raleigh, North Carolina) |
ABSTRACT | Provided are stem cell biomimetic microparticles comprised of at least one stem cell-derived paracrine polypeptide or growth factor embedded in a polymer core particle that further comprises an outer layer of at least one fragment of a cell membrane of a stem cell disposed on the core particle. The polymer core may be constituted of any biocompatible and biodegradable polymer or copolymer, or a combination thereof that allows the embedding of the paracrine factors and their prolonged release from the core. The core and hence the microparticles can be biodegradable, allowing eventual elimination from the recipient animal or human subject. The core particles are sized to allow both transport through blood vessels and extravasation from the blood vessels into the surrounding tissues. The core particle may further include at least one polypeptide or peptide growth factor to induce the generation and proliferation of a population of stem cells. |
FILED | Thursday, September 28, 2017 |
APPL NO | 16/337635 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 9/0019 (20130101) A61K 9/5031 (20130101) A61K 9/5068 (20130101) A61K 9/5089 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 38/18 (20130101) A61K 47/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564911 | Liedtke |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Wolfgang Liedtke (Durham, North Carolina) |
ABSTRACT | Provided are methods of sanitizing a subject, and methods of anesthetizing a subject. Further provided are methods of treating and/or preventing dermatological disorders, reducing skin inflammation, reducing pain, and/or reducing itch in a subject in need thereof. The methods may include administering to the subject an effective amount of a TRPA1 and/or TRPV4 inhibitor. Further provided are compositions including a TRPA1 and/or TRPV4 inhibitor compound in combination with a carrier, vehicle, or diluent that is suitable for topical application. |
FILED | Friday, April 07, 2017 |
APPL NO | 16/091960 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) Original (OR) Class A61K 31/426 (20130101) A61K 31/4439 (20130101) A61K 31/4439 (20130101) A61K 33/18 (20130101) A61K 33/18 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/02 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564913 | Nassar et al. |
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APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
INVENTOR(S) | Nicolas Nassar (Cincinnati, Ohio); William Seibel (Liberty Township, Ohio); Anjelika Gasilina (Bethesda, Maryland); Jose Cancelas (Cincinnati, Ohio) |
ABSTRACT | A small molecule compound IODVA1 has been found to have cellular inhibitory activity against several transformed cell lines including Ras-driven cells. IODVA1 decreases cell-cell and cell-extra cellular matrix interactions and reduces growth of Ras-driven tumors. Applicants also synthesized compound NIRA2 and showed in vitro and in vivo efficacy and potency against models of Ph+(BCR-ABL1) B-ALL and of colon adenocarcinoma xenografts. |
FILED | Friday, May 01, 2020 |
APPL NO | 16/864961 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) A61K 31/444 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564914 | Trindade Da Silva et al. |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); Carlos Antonio Trindade Da Silva (Uberlandia, Brazil) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); Carlos Antonio Tindade Da Silva (Uberlandia, Brazil) |
INVENTOR(S) | Carlos Antonio Trindade Da Silva (Uberlandia, Brazil); Buce D. Hammock (Davis, California); Fawaz G. Haj (Davis, California); Ahmed Bettaieb (Knoxville, Tennessee); Ahmet Bora Inceoglu (Davis, California) |
ABSTRACT | Provided are compositions and methods for preventing, mitigating, decreasing, inhibiting and/or reversing bone loss and/or increasing and/or promoting bone regeneration and remodeling and/or preventing, mitigating, decreasing, inhibiting and/or reversing periodontitis and/or periodontal disease in a subject by administering to the subject an effective amount of an inhibitor of soluble epoxide hydrolase (sEH). |
FILED | Thursday, June 08, 2017 |
APPL NO | 16/308672 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0053 (20130101) A61K 9/0056 (20130101) A61K 31/4468 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/08 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564932 | Szmulewitz et al. |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Russell Z. Szmulewitz (Chicago, Illinois); Suzanne D. Conzen (Park Ridge, Illinois) |
ABSTRACT | Embodiments of the invention are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity. |
FILED | Friday, June 26, 2020 |
APPL NO | 16/913916 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/567 (20130101) Original (OR) Class A61K 31/567 (20130101) A61K 31/569 (20130101) A61K 31/569 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 31/4166 (20130101) A61K 31/4166 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564936 | Imai et al. |
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APPLICANT(S) | Washington University (St. Louis, Missouri) |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Shin-ichiro Imai (St. Louis, Missouri); Alessia Grozio (St. Louis, Missouri) |
ABSTRACT | Various methods and compositions for treating age-associated conditions and other medical conditions, such as muscle diseases, type 2 diabetes, and/or obesity are described. Methods of enhancing cellular uptake of NMN and stimulating NAD+ production are further described. Various mammalian cells and mammalian cell lines are described including those comprising a cDNA encoding a Slc12a8 protein. Gene therapy vectors comprising a nucleic acid encoding Slc12a8 and non-human animals comprising an inactivating mutation in a Slc12a8 gene are also disclosed. Also described are methods for screening a candidate compound to identify compounds that promote NMN transport. |
FILED | Friday, August 10, 2018 |
APPL NO | 16/638064 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/706 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 48/005 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2740/15032 (20130101) C12N 2740/15043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/6803 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564949 | Kriegstein et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Arnold Kriegstein (Mill Valley, California); John L. R. Rubenstein (San Francisco, California); Scott C. Baraban (Novato, California); Arturo Alvarez-Buylla (Woodside, California) |
ABSTRACT | The present disclosure provides methods for the treatment of a mammal having a neurological condition, disease, or injury. The methods involve increasing the number of functional GABAergic interneurons at or near the site of the neurological disease, injury, or condition. |
FILED | Friday, August 14, 2020 |
APPL NO | 16/993914 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 35/30 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0618 (20130101) C12N 5/0622 (20130101) C12N 2506/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/28 (20130101) G01N 2800/2835 (20130101) G01N 2800/2842 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564973 | Van Den Brink et al. |
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FUNDED BY |
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APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); EVIVE BIOTECHNOLOGY (SHANGHAI) LTD. (Shanghai, China PRC) |
ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); EVIVE BIOTECHNOLOGY (SHANGHAI) LTD (Shanghai, China PRC) |
INVENTOR(S) | Marcel Van Den Brink (New York, New York); Alan Hanash (New York, New York); Caroline Lindemans (Utrecht, Netherlands); Tom Tang (Shanghai, China PRC) |
ABSTRACT | The present invention provides methods and compositions for the use of IL-22 for treating conditions of intestinal injury and inflammatory conditions such as graft vs. host disease. Specifically, IL-22 can be used to increase Intestinal Stem Cell (ISC) recovery and for enhancing immune reconstitution following allogeneic hematopoietic transplantation. In particularly preferred embodiments, the present invention provides methods of using therapeutic IL-22, including a dimeric form of IL-22, in therapeutic compositions for treating graft vs. host disease, including hepatic, thymic, gastrointestinal, or other graft vs. host disease in hematopoietic stem cell transplant patients and in patients with inflammatory intestinal conditions. |
FILED | Monday, December 23, 2019 |
APPL NO | 16/724491 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/20 (20130101) Original (OR) Class Peptides C07K 14/54 (20130101) C07K 16/42 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564977 | Childers et al. |
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FUNDED BY |
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APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina); Genethon (Evry, France); Children's Medical Center Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | Wake Forest University Health Sciences (Winston Salem, North Carolina); Genethon (Evry, France); Children's Medical Center Corporation (Boston, Massachusetts) |
INVENTOR(S) | Martin K. Childers (Seattle, Washington); Alan H. Beggs (Needham, Massachusetts); Ana Maria Buj Bello (Paris, France) |
ABSTRACT | The present invention provides compositions and methods for treating a myopathy. In certain embodiments, the invention provides compositions and methods for treating, improving muscle function, and prolonging survival in a subject with X-linked myotubular myopathy (XLMTM). The present invention provides a method comprising systemic administration of a composition that induces the increased expression of myotubularin in the muscle of a subject. The invention provides sustained regional and global increases in muscle function. |
FILED | Thursday, December 28, 2017 |
APPL NO | 15/856653 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) Original (OR) Class A61K 48/005 (20130101) A61K 48/0058 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/16 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 301/03 (20130101) C12Y 301/03064 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564982 | Bakaletz et al. |
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FUNDED BY |
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APPLICANT(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
ASSIGNEE(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
INVENTOR(S) | Lauren O. Bakaletz (Hilliard, Ohio); Steven D. Goodman (Hilliard, Ohio) |
ABSTRACT | The disclosure provides methods and compositions that are useful to lessen and/or cure bacterial biofilms and treat diseases or disorders associated with biofilms using one or more novel polypeptide vaccines, antibodies, antibody fragments and compositions. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics. |
FILED | Wednesday, January 03, 2018 |
APPL NO | 16/475656 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/50 (20200101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/102 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 14/285 (20130101) C07K 16/1242 (20130101) C07K 2317/20 (20130101) C07K 2317/24 (20130101) C07K 2317/55 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/285 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564991 | Bidwell, III et al. |
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FUNDED BY |
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APPLICANT(S) | University of Mississippi Medical Center (Jackson, Mississippi) |
ASSIGNEE(S) | University of Mississippi Medical Center (Jackson, Mississippi) |
INVENTOR(S) | Gene L. Bidwell, III (Brandon, Mississippi); Alejandro R. Chade (Brandon, Mississippi) |
ABSTRACT | A renal cortex targeting elastin-like polypeptide (ELP), a renal medulla and cortex targeting ELP, and a method of treating a renal disorder are provided. The renal cortex targeting ELP includes up to 95 repeat units having the sequence VPGXG (SEQ ID NO: 1), where X in each of the repeat units is any amino acid except proline. The renal medulla and cortex targeting ELP includes at least 95 repeat units of SEQ ID NO: 1, where X in each of the repeat units is any amino acid except proline. The method of treating a renal disorder includes administering an ELP and a therapeutic drug to a subject in need thereof, where the ELP includes up to 671 repeat units of SEQ ID NO: 1 and X in each of the repeat units is any amino acid except proline. |
FILED | Monday, March 30, 2020 |
APPL NO | 16/834715 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/39 (20130101) A61K 38/1866 (20130101) A61K 47/64 (20170801) Original (OR) Class A61K 47/6435 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565000 | Schaffer et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | David V. Schaffer (Danville, California); John G. Flannery (Berkeley, California); William A. Beltran (Philadelphia, Pennsylvania); Leah C. Byrne (San Francisco, California); Meike Visel (El Cerrito, California) |
ABSTRACT | The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease. |
FILED | Thursday, June 16, 2022 |
APPL NO | 17/842553 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 48/0075 (20130101) A61K 48/0091 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565001 | Schaffer et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | David V. Schaffer (Danville, California); John G. Flannery (Berkeley, California); William A. Beltran (Philadelphia, Pennsylvania); Leah C. Byrne (San Francisco, California); Meike Visel (El Cerrito, California) |
ABSTRACT | The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease. |
FILED | Thursday, June 16, 2022 |
APPL NO | 17/842639 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 48/0075 (20130101) A61K 48/0091 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565002 | Sullenger et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Bruce A. Sullenger (Durham, North Carolina); Kady-Ann C. Steen-Burrell (Durham, North Carolina); Bethany Powell Gray (Durham, North Carolina) |
ABSTRACT | Provided herein are imaging agents, antidotes to the imaging agents and methods of using the same to image a thrombus or blood clot or thrombin including sites of thrombin accumulation and to diagnose and treat thrombosis. The imaging agents include an aptamer capable of binding the thrombus or thrombin in particular linked to a reporter moiety. The imaging agents may be used to label the thrombus or sites of thrombin accumulation. Antidotes capable of binding to the aptamer in the imaging agent are also provided. The antidotes may further be linked to a quencher capable of quenching the reporter moiety. |
FILED | Thursday, May 21, 2020 |
APPL NO | 16/880791 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) Original (OR) Class A61K 49/0021 (20130101) A61K 49/0032 (20130101) A61K 49/0054 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/113 (20130101) C12N 2310/317 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/3517 (20130101) C12N 2310/3521 (20130101) C12N 2310/3533 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565005 | Cheal et al. |
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FUNDED BY |
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APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
INVENTOR(S) | Sarah M. Cheal (New York, New York); Michael McDevitt (New York, New York); Ouathek Ouerfelli (New York, New York); Steven M. Larson (New York, New York); Guangbin Yang (New York, New York) |
ABSTRACT | The present disclosure provides compositions and methods for the detection and treatment of cancer. Specifically, the compositions of the present technology include novel DOTA-haptens that may be complexed with a radioisotope (e.g., 225Ac). Also disclosed herein are methods of the using the DOTA-haptens of the present technology in diagnostic imaging as well as pretargeted radioimmunotherapy. |
FILED | Thursday, July 05, 2018 |
APPL NO | 16/628068 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0482 (20130101) Original (OR) Class A61K 51/1045 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/003 (20130101) Peptides C07K 16/32 (20130101) C07K 16/44 (20130101) C07K 2317/31 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565024 | Garcia et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Andres J. Garcia (Atlanta, Georgia); Christopher Thomas Johnson (Atlanta, Georgia) |
ABSTRACT | Disclosed herein are synthetic hydrogels suitable for delivering antimicrobial proteins, optionally in combination with bone regenerating agents to injured tissues. The hydrogels can include lysostaphin and one or more bone morphogenic proteins. The hydrogels are composed of a network of crosslinked hydrophilic polymers and adhesion peptides. |
FILED | Thursday, November 15, 2018 |
APPL NO | 16/191685 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) A61K 38/16 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/26 (20130101) A61L 27/48 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/227 (20130101) A61L 2300/25 (20130101) A61L 2300/252 (20130101) A61L 2300/404 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2430/02 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/19 (20130101) A61M 5/3294 (20130101) A61M 2202/07 (20130101) A61M 2210/02 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565128 | Larochelle et al. |
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FUNDED BY |
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APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
INVENTOR(S) | Ethan Phillip M. Larochelle (Thetford Center, Vermont); Brian W. Pogue (Hanover, New Hampshire) |
ABSTRACT | In an embodiment, the present disclosure pertains to a method of determining optimal parameters for application of light from a light source to a tissue. In general, the method includes one or more of the following steps of: (1) utilizing an algorithm to generate results related to estimating light flow from the light source into the tissue; and (2) utilizing the results to determine optimal parameters for applying the light source to the tissue. In some embodiments, the method of the present disclosure further includes the step of: (3) applying the light source to the tissue using the optimal parameters; and (4) treating a condition associated with the tissue. |
FILED | Tuesday, June 30, 2020 |
APPL NO | 16/916852 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/1031 (20130101) Original (OR) Class A61N 5/1048 (20130101) A61N 2005/0627 (20130101) A61N 2005/1034 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565256 | Reiserer et al. |
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FUNDED BY |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
INVENTOR(S) | Ronald S. Reiserer (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); Philip C. Samson (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Michael Geuy (Nashville, Tennessee); Lisa J. McCawley (Nashville, Tennessee); John P. Wikswo (Brentwood, Tennessee) |
ABSTRACT | Microfluidic systems, pumps, valves and applications of the same are provided. The microfluidic system may be a pump or a valve having a fluidic chip and an actuator controlling the opening and closing of the fluidic channel in the fluidic chip. The actuator may be disposed to tilt from the fluidic chip, forming a tilted-rotor peristaltic pump. Alternatively, the actuator may be a rolling ball actuator, and different fluidic chips may be used in different applications. For example, the fluidic chip may be a spiral pump chip having spiral channels, a rotary peristaltic pump chip having multiple output channels, or a multi-port valve chip having one port interconnected with multiple different ports. An analytical valve chip may switchably interconnect bioreactor and rinse/calibration input channels to sensor and waste output channels. The actuator of a random-access valve can move from one valve position to another without opening or closing intermediate ones. |
FILED | Monday, June 29, 2020 |
APPL NO | 17/623350 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) Original (OR) Class B01L 2300/123 (20130101) B01L 2300/0627 (20130101) B01L 2400/0644 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/1261 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/163 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565264 | Sabaawy et al. |
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FUNDED BY |
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APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
INVENTOR(S) | Hatem E. Sabaawy (New Brunswick, New Jersey); Howon Lee (Piscataway, New Jersey); Chen Yang (New Brunswick, New Jersey); Daehoon Han (New Brunswick, New Jersey) |
ABSTRACT | An expandable array and methods of maintaining a biological sample within an expandable array are provided. The expandable array includes a plurality of receptacles configured to receive a biological sample and a plurality of beams comprising a programmable material. Each beam of the plurality of beams is located between and connects at least two receptacles. The programmable material can be a shape-memory polymer or a magnetoactive material that transitions the plurality of beams from an extended state to a contracted state upon application of a stimulus. |
FILED | Friday, October 30, 2020 |
APPL NO | 17/085985 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50855 (20130101) Original (OR) Class B01L 2300/18 (20130101) B01L 2300/0636 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
11565994 — Inhibitors of histone lysine specific demethylase (LSD1) and histone deacetylases (HDACS)
US 11565994 | Cole et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Philip Cole (Baltimore, Maryland); Shonoi Ming (Baltimore, Maryland); Polina Prusevich (Baltimore, Maryland); Jay Kalin (Baltimore, Maryland) |
ABSTRACT | A series of phenelzine analogs comprising a phenelzine scaffold linked to an aromatic moiety and their use as inhibitors of lysine-specific demethylase 1 (LSD1) and/or one or more histone deacetylases (HDACs) is provided. The presently disclosed phenelzine analogs exhibit potency and selectivity for LSD1 versus MAO and LSD2 enzymes and exhibit bulk, as well as, gene specific histone methylation changes, anti-proliferative activity in several cancer cell lines, and neuroprotection in response to oxidative stress. Accordingly, the presently disclosed phenelzine analogs can be used to treat diseases, conditions, or disorders related to LSD1 and/or HDACs, including, but not limited to, cancers and neurodegenerative diseases. |
FILED | Thursday, June 04, 2020 |
APPL NO | 16/892825 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/137 (20130101) A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/255 (20130101) A61K 31/325 (20130101) A61K 31/405 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Acyclic or Carbocyclic Compounds C07C 233/29 (20130101) C07C 243/18 (20130101) Original (OR) Class C07C 259/06 (20130101) C07C 271/02 (20130101) C07C 309/66 (20130101) C07C 2602/02 (20170501) Heterocyclic Compounds C07D 209/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566015 | Han et al. |
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FUNDED BY |
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APPLICANT(S) | Crinetics Pharmaceuticals, Inc. (San Diego, California) |
ASSIGNEE(S) | CRINETICS PHARMACEUTICALS, INC. (San Diego, California) |
INVENTOR(S) | Sangdon Han (San Diego, California); Yunfei Zhu (San Diego, California); Sun Hee Kim (San Diego, California); Jian Zhao (San Diego, California); Shimiao Wang (San Diego, California) |
ABSTRACT | Described herein are compounds that are melanocortin subtype-2 receptor (MC2R) modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of MC2R activity. |
FILED | Monday, February 08, 2021 |
APPL NO | 17/170396 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 295/04 (20130101) C07D 401/10 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 407/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566016 | Arancio et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York); Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York); Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Ottavio Arancio (New York, New York); Daniel Martin Watterson (Douglas, Michigan); Jeffrey Claude Pelletier (Lafayette Hill, Pennsylvania); Saktimayee Mitra Roy (Evanston, Illinois) |
ABSTRACT | The invention provides for novel MAP kinase inhibitors and compositions comprising the same. In some embodiments, the MAP kinase inhibitors are p38α MAP kinase inhibitors. The invention further provides for methods for treatment of diseases comprising administration of MAP kinase inhibitors or compositions comprising MAP kinase inhibitors. In some embodiments, the disease is Alzheimer's Disease, ALS, Huntington's Disease or Parkinson's Disease. |
FILED | Thursday, September 16, 2021 |
APPL NO | 17/476648 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566019 | Pathak et al. |
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FUNDED BY |
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APPLICANT(S) | Southern Research Institute (Birmingham, Alabama); Oregon Health and Science University (Portland, Oregon) |
ASSIGNEE(S) | Southern Research Institute (Birmingham, Alabama); Oregon Health and Science University (Portland, Oregon) |
INVENTOR(S) | Ashish Kumar Pathak (Birmingham, Alabama); Corinne E. Augelli-Szafran (Homewood, Alabama); Atefeh Garzan (Hoover, Alabama); Daniel Streblow (Banks, Oregon); Nicole Haese (Beaverton, Oregon) |
ABSTRACT | The present disclosure is concerned with 2-pyrimidone compounds that are capable of inhibiting a viral infection and methods of treating alphavirus viral infections such as, for example, chikungunya, Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), and Venezuelan equine encephalitis using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
FILED | Friday, April 02, 2021 |
APPL NO | 17/221666 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 213/69 (20130101) C07D 213/70 (20130101) C07D 213/74 (20130101) C07D 403/04 (20130101) Original (OR) Class C07D 491/052 (20130101) C07D 498/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566046 | Krusemark et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Casey J. Krusemark (West Lafayette, Indiana); Emily C. Dykhuizen (West Lafayette, Indiana); Sijie Wang (Lafayette, Indiana) |
ABSTRACT | The present invention relates to series of peptidomimetic compounds selectively targeting CBX8 of polycomb chromobox protein homolog proteins. Pharmaceutical compositions of those compounds and methods of using them in the treatment of diseases involved CBX8 pharmacology, including various cancers and leukemia, by administering therapeutically effective amounts of such compound alone or together with other therapeutics, are within the scope of this disclosure. |
FILED | Friday, June 05, 2020 |
APPL NO | 16/894036 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Peptides C07K 5/1016 (20130101) C07K 7/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566050 | Lindesmith et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Lisa Chon Lindesmith (Apex, North Carolina); Ralph Steven Baric (Haw River, North Carolina); Kari Moore Debbink (Ann Arbor, Michigan); Eric Francis Donaldson (Durham, North Carolina) |
ABSTRACT | The present invention is directed to methods and compositions for norovirus therapeutics, such as vaccines, and diagnostics. |
FILED | Thursday, October 18, 2018 |
APPL NO | 16/756740 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/16022 (20130101) C12N 2770/16023 (20130101) C12N 2770/16034 (20130101) C12N 2770/36142 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566077 | Gajewski et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Thomas Gajewski (Chicago, Illinois); Jason Williams (Chicago, Illinois); Brendan Horton (Chicago, Illinois) |
ABSTRACT | Provided herein are compositions and methods for detecting and/or targeting dysfunctional tumor antigen-specific CD8+ T cells in the tumor microenvironment for diagnostic, therapeutic and/or research applications. In particular, dysfunctional tumor antigen-specific CD8+ T cells are detected and/or targeted via their expression of cell surface receptors described herein, such as 4-1BB, LAG-3, or additional markers that correlate with 4-1BB and LAG-3 expression, such as markers differentially expressed on the surface of the T cells. |
FILED | Wednesday, January 17, 2018 |
APPL NO | 16/476219 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 16/2803 (20130101) C07K 16/2878 (20130101) Original (OR) Class C07K 2317/75 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566081 | Roberts et al. |
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FUNDED BY |
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APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas); Arkansas Children's Research Institute (Little Rock, Arkansas) |
ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas); Arkansas Children's Research Institute (Little Rock, Arkansas) |
INVENTOR(S) | Dean W. Roberts (Little Rock, Arkansas); Laura James (Little Rock, Arkansas); Jack Hinson (Little Rock, Arkansas) |
ABSTRACT | The present disclosure provides isolated antibodies that bind to acetaminophen-protein adducts that are useful in the detection and diagnosis of acetaminophen-induced toxicity. |
FILED | Friday, January 10, 2020 |
APPL NO | 16/740030 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/44 (20130101) Original (OR) Class C07K 19/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/9486 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566213 | Allbritton et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | Nancy L. Allbritton (Chapel Hill, North Carolina); Yuli Wang (Cary, North Carolina); Christopher Sims (Chapel Hill, North Carolina) |
ABSTRACT | A microfabricated device having at least one gas-entrapping feature formed therein in a configuration that entraps air bubbles upon wetting the feature with a solvent or solution is described. The device includes a sacrificial residue in contact with the gas-entrapping feature, the dissolution of which guides the wetting of the gas-entrapping feature. |
FILED | Monday, July 29, 2019 |
APPL NO | 16/525191 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502707 (20130101) B01L 2200/12 (20130101) B01L 2200/0684 (20130101) B01L 2300/161 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/058 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00206 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 29/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2035/00158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566214 | Thon et al. |
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FUNDED BY |
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APPLICANT(S) | BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); Vilnius University (Vilnius, Lithuania) |
ASSIGNEE(S) | BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); VILNIUS UNIVERSITY (Vilnius, Lithuania) |
INVENTOR(S) | Jonathan N. Thon (Brookline, Massachusetts); Joseph E. Italiano (Chestnut Hill, Massachusetts); Linas Mazutis (Boston, Massachusetts); David A. Weitz (Boston, Massachusetts) |
ABSTRACT | Systems and methods generating physiologic models that can produce functional biological substances are provided. In some aspects, a system includes a substrate and a first and second channel formed therein. The channels extend longitudinally and are substantially parallel to each other. A series of apertures extend between the first channel and second channel to create a fluid communication path passing through columns separating the channels that extends further along the longitudinal dimension than other dimensions. The system also includes a first source configured to selectively introduce into the first channel a first biological composition at a first channel flow rate and a second source configured to selectively introduce into the second channel a second biological composition at a second channel flow rate, wherein the first channel flow rate and the second channel flow rate create a differential configured to generate physiological shear rates within a predetermined range in the channels. |
FILED | Monday, February 17, 2020 |
APPL NO | 16/792484 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2200/0605 (20130101) B01L 2200/0647 (20130101) B01L 2300/163 (20130101) B01L 2300/0681 (20130101) B01L 2300/0867 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0644 (20130101) C12N 2521/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566224 | Murthy et al. |
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FUNDED BY |
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APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Shashi K. Murthy (Newton, Massachusetts); Bradley B. Collier (Jamaica Plain, Massachusetts) |
ABSTRACT | Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease. |
FILED | Thursday, June 18, 2020 |
APPL NO | 16/905615 |
ART UNIT | 1799 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 14/525 (20130101) C07K 14/535 (20130101) C07K 14/545 (20130101) C07K 14/5406 (20130101) C07K 14/5412 (20130101) Apparatus for Enzymology or Microbiology; C12M 1/22 (20130101) C12M 23/16 (20130101) C12M 23/42 (20130101) C12M 25/02 (20130101) C12M 29/10 (20130101) C12M 41/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0639 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566237 | Jones et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Peter L. Jones (Carson City, Nevada); Charis L. Himeda (Reno, Nevada); Takako Jones (Carson City, Nevada) |
ABSTRACT | The disclosure relates to methods and compositions for regulating expression of DUX4. Specifically, the disclosure provides a recombinant gene editing complex comprising: a recombinant gene editing protein; and, a nucleic acid encoding a guide RNA (gRNA) that specifically hybridizes to a target nucleic acid sequence encoding a D4Z4 macrosatellite repeat region, wherein binding of the complex to the target nucleic acid sequence results in inhibition of DUX4 gene expression. In some aspects, methods described by the disclosure are useful for treating a disease associated with aberrant DUX4 expression (e.g., facioscapulohumeral muscular dystrophy, FSHD). |
FILED | Friday, September 22, 2017 |
APPL NO | 16/334826 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2750/14141 (20130101) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566238 | Sonnenburg et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Novome Biotechnologies, Inc. (Daly City, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Novome Biotechnologies, Inc. (Daly City, California) |
INVENTOR(S) | Justin L. Sonnenburg (Redwood City, California); Weston R. Whitaker (Daly City, California); Elizabeth Stanley (Portola Valley, California); William C. DeLoache (Oakland, California) |
ABSTRACT | Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome. |
FILED | Thursday, December 14, 2017 |
APPL NO | 16/468542 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/741 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/2402 (20130101) Original (OR) Class C12N 15/52 (20130101) C12N 15/74 (20130101) Enzymes C12Y 302/01178 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566242 | Kogut et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
INVENTOR(S) | Igor Kogut (Aurora, Colorado); Dennis R. Roop (Greenwood Village, Colorado); Ganna Bilousova (Aurora, Colorado); Patrick S. McGrath (Denver, Colorado) |
ABSTRACT | The present disclosure relates to methods and compositions for reprogramming cells to a pluripotent state. In particular, it relates to an integration- and feeder cell-free method for reprogramming primary human fibroblast cells to induced pluripotent stem cells (iPSCs). |
FILED | Friday, April 20, 2018 |
APPL NO | 15/958965 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 35/28 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0652 (20130101) C12N 5/0696 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2310/141 (20130101) C12N 2330/31 (20130101) C12N 2500/60 (20130101) C12N 2501/65 (20130101) C12N 2501/115 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566243 | Brar et al. |
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FUNDED BY |
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APPLICANT(S) | JAAN BIOTHERAPEUTICS, LLC (San Diego, California) |
ASSIGNEE(S) | Jaan Biotherapeutics LLC (San Diego, California) |
INVENTOR(S) | Bhawanjit Kaur Brar (La Jolla, California); Eric G. Marcusson (San Francisco, California) |
ABSTRACT | Disclosed herein include microRNA antagonists, therapeutic compositions that include one or more of such microRNA antagonists, and methods of treating and/or ameliorating cardiac diseases and/or muscular dystrophy disorders with the microRNA antagonists. Also included are combination therapies, wherein a therapeutic composition disclosed herein and an additional therapy agent are provided to a subject having or suspected of having cardiac disease and/or muscular dystrophy disorder. In particular, some embodiments disclosed herein relate to compositions and methods for transiently administering a mixture of microRNA antagonists for promoting cardiomyocyte proliferation and cardiac regeneration. |
FILED | Monday, July 17, 2017 |
APPL NO | 16/318353 |
ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/141 (20130101) C12N 2310/315 (20130101) C12N 2310/344 (20130101) C12N 2310/346 (20130101) C12N 2310/3231 (20130101) C12N 2750/14143 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566247 | Chandler et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
ASSIGNEE(S) | |
INVENTOR(S) | Dawn Suzan Chandler (Bexley, Ohio); Daniel Forrest Comiskey (Columbus, Ohio) |
ABSTRACT | Compositions and methods for treating cancer in a subject in need thereof are described that includes administering a therapeutically effective amount of an oligonucleotide that inhibits the binding of splicing regulator SRSF1 or SRSF2 to MDM2 exon 4 or 11. |
FILED | Tuesday, July 23, 2019 |
APPL NO | 16/519211 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7088 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1135 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/3521 (20130101) C12N 2320/33 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566265 | Ajikumar et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); National University of Singapore (Singapore, Singapore) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); National University of Singapore (Singapore, Singapore) |
INVENTOR(S) | Parayil K. Ajikumar (Cambridge, Massachusetts); Gregory Stephanopoulos (Winchester, Massachusetts); Heng Phon Too (Singapore, Singapore) |
ABSTRACT | The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids. |
FILED | Friday, May 07, 2021 |
APPL NO | 17/314561 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) Original (OR) Class C12P 7/42 (20130101) C12P 9/00 (20130101) C12P 15/00 (20130101) C12P 17/02 (20130101) C12P 19/56 (20130101) C12P 23/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 2600/158 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566268 | Clarke et al. |
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FUNDED BY |
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APPLICANT(S) | ISIS INNOVATION LTD (Oxfordshire, United Kingdom); GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
ASSIGNEE(S) | GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); OXFORD UNIVERSITY INNOVATION LIMITED (Oxford, United Kingdom) |
INVENTOR(S) | Kieran Clarke (Oxford, United Kingdom); Richard Lewis Veech (Rockville, Maryland); M. Todd King (Rockville, Maryland) |
ABSTRACT | Embodiments of the present invention are directed to processes for the production of (R)-3-hydroxybutyl (R)-3-hydroxybyrate. Poly (R)-3-hydroxybyrate is transesterified with an alcohol, to form a first ester portion and a second ester portion. The first ester portion is reduced to the diol to form a diol portion and the diol portion is reacted with the second ester portion to produce (R)-3-hydroxybutyl (R)-3-hydroxybyrate. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/213713 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 29/147 (20130101) C07C 29/147 (20130101) C07C 31/207 (20130101) C07C 67/03 (20130101) C07C 67/03 (20130101) C07C 69/675 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566272 | Robinson et al. |
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FUNDED BY |
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APPLICANT(S) | University of Oregon (Eugene, Oregon) |
ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
INVENTOR(S) | Catherine Robinson (Eugene, Oregon); Emily Sweeney (Eugene, Oregon); Karen Guillemin (Eugene, Oregon) |
ABSTRACT | Provided are SpdE polypeptides and variants and nucleic acids encoding the SpdE polypeptides and variants. Also provided are vectors including one or more nucleic acids encoding a SpdE polypeptide or variant and cells including a nucleic acid encoding the SpdE polypeptide or variant, as well as cells expressing a SpdE polypeptide or variant and compositions including such cells and a pharmaceutically acceptable carrier. Finally, methods of detecting presence and/or amount of one or more amino acids in a sample are provided. The methods include contacting the sample with a SpdE protein, measuring diguanylate cyclase activity of the SpdE protein; and comparing the diguanylate cyclase activity of the SpdE protein to a control. The methods can utilize isolated SpdE protein or a cell expressing a SpdE protein. |
FILED | Wednesday, July 08, 2020 |
APPL NO | 16/923816 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Peptides C07K 14/195 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1241 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Original (OR) Class Enzymes C12Y 207/07065 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6806 (20130101) G01N 2333/9125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566276 | Church et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | George M. Church (Brookline, Massachusetts); Jehyuk Lee (Allston, Massachusetts); Daniel Levner (Boston, Massachusetts); Michael Super (Lexington, Massachusetts) |
ABSTRACT | Methods of making a three-dimensional matrix of nucleic acids within a cell is provided. |
FILED | Friday, July 02, 2021 |
APPL NO | 17/366151 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 1/6837 (20130101) C12Q 1/6844 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 2458/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566277 | Church et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | George M. Church (Brookline, Massachusetts); Jehyuk Lee (Allston, Massachusetts); Daniel Levner (Boston, Massachusetts); Michael Super (Lexington, Massachusetts) |
ABSTRACT | Methods of analyzing nucleic acids of a cell are provided. |
FILED | Tuesday, February 15, 2022 |
APPL NO | 17/671803 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6816 (20130101) C12Q 1/6837 (20130101) C12Q 1/6844 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 2458/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566279 | Regev et al. |
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FUNDED BY |
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APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Evan Zane Macosko (Cambridge, Massachusetts); Steven Andrew McCarroll (Cambridge, Massachusetts); Alexander K. Shalek (Cambridge, Massachusetts); Anindita Basu (Cambridge, Massachusetts); Christopher B. Ford (Cambridge, Massachusetts); Hongkun Park (Cambridge, Massachusetts); David A. Weitz (Cambridge, Massachusetts) |
ABSTRACT | The present invention generally relates to a combination of molecular barcoding and emulsion-based microfluidics to isolate, lyse, barcode, and prepare nucleic acids from individual cells in a high-throughput manner. |
FILED | Wednesday, January 09, 2019 |
APPL NO | 16/244058 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1096 (20130101) C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) Original (OR) Class C12Q 1/6809 (20130101) C12Q 1/6834 (20130101) C12Q 1/6834 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2521/107 (20130101) C12Q 2521/107 (20130101) C12Q 2521/107 (20130101) C12Q 2525/15 (20130101) C12Q 2525/15 (20130101) C12Q 2525/15 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/155 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/173 (20130101) C12Q 2525/173 (20130101) C12Q 2525/173 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2563/149 (20130101) C12Q 2563/159 (20130101) C12Q 2563/159 (20130101) C12Q 2563/159 (20130101) C12Q 2563/179 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566285 | Salk et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
FILED | Wednesday, July 03, 2019 |
APPL NO | 16/503398 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566286 | Salk et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
FILED | Monday, June 28, 2021 |
APPL NO | 17/361245 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566287 | Salk et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
FILED | Monday, August 02, 2021 |
APPL NO | 17/392180 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566288 | Salk et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
FILED | Monday, August 02, 2021 |
APPL NO | 17/392193 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566293 | Su et al. |
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FUNDED BY |
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APPLICANT(S) | University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
INVENTOR(S) | Sheng-Fang Su (Los Angeles, California); Gangning Liang (Los Angeles, California); Peter Jones (Los Angeles, California); Kimberly Siegmund (Los Angeles, California) |
ABSTRACT | A method for the prediction, prognosis and/or diagnosis of bladder cancer or bladder cancer recurrence in a subject, the method includes: providing a test sample from the subject; measuring DNA methylation levels of at least a portion of two or more polynucleotides selected from the group consisting of HOXA9, SOX1, NPY, IRAK3, L1-MET, and ZO2 in the test sample; calculating a risk score based on the measured DNA methylation levels, comparing the calculated risk score to a cut-off value derived from a reference DNA methylation profile based on DNA methylation levels of the one or more biomarkers derived from a control group, members of which had bladder cancer; and based on the comparison calculated risk score to the cut-off value, determining at least one of: (1) whether bladder cancer has recurred; (2) whether there is likelihood that the bladder cancer will recur; and (3) whether the patient has bladder cancer. |
FILED | Monday, February 24, 2020 |
APPL NO | 16/799559 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567020 | Potyrailo |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York) |
ABSTRACT | A gas sensing assembly includes a sensing material to be placed in contact with a fluid sample, electrodes coupled with the sensing material that apply an electric field to the sensing material across the electrodes, a heating element that controls a temperature of the sensing material while the sensing material is in contact with the fluid sample, and sensing circuitry to control application of the electric field to the sensing material via the electrodes at an alternating current frequency range in the presence of an uncontrolled ambient temperature and at an elevated alternating current frequency range. The sensing circuitry measures one or more electrical responses of the sensing material responsive to applying the electric field at the alternating current frequency range and at the elevated alternating current frequency range. The sensing circuitry detects presence of a gas in the fluid sample based on the one or more electrical responses. |
FILED | Sunday, October 13, 2019 |
APPL NO | 16/600520 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/06 (20130101) G01N 27/026 (20130101) Original (OR) Class G01N 27/125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567031 | Zeng et al. |
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FUNDED BY |
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APPLICANT(S) | Oakland University (Rochester, Michigan) |
ASSIGNEE(S) | Oakland University (Rochester, Michigan) |
INVENTOR(S) | Xiangqun Zeng (Rochester Hills, Michigan); Yongan Tang (Huntley, Illinois) |
ABSTRACT | In an example of a selective, real-time gas sensing method, a gas sample, potentially including a specific gas molecule to be sensed, is supplied to an interface between a working electrode and an ionic liquid electrolyte. Based on at least one unique electrochemical reaction of the specific gas molecule to be sensed, a driving force is implemented to initiate a series of reactions involving the specific gas molecule. In response to the implementation of the driving force, a signal indicative of the specific gas molecule is monitored for. |
FILED | Thursday, September 06, 2018 |
APPL NO | 16/123643 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 2560/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/407 (20130101) G01N 27/4045 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567063 | Silva et al. |
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FUNDED BY |
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APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
ASSIGNEE(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
INVENTOR(S) | Ariosto S. Silva (Tampa, Florida); Zayar P. Khin (Tampa, Florida) |
ABSTRACT | Disclosed is a method for selecting a cancer treatment regimen for a subject. |
FILED | Friday, November 14, 2014 |
APPL NO | 15/036951 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 2010/0258 (20130101) Apparatus for Enzymology or Microbiology; C12M 41/46 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1475 (20130101) G01N 15/1484 (20130101) G01N 21/763 (20130101) G01N 21/6458 (20130101) G01N 33/5011 (20130101) Original (OR) Class G01N 33/5047 (20130101) G01N 33/57426 (20130101) G01N 2015/1006 (20130101) G01N 2201/0221 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567074 | Yates et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Nathan A. Yates (Piscataway, New Jersey); Steven James Mullett (McMurray, Pennsylvania); Harris B. Bell-Temin (Gibsonia, Pennsylvania); Andrey Bondarenko (Pittsburgh, Pennsylvania) |
ABSTRACT | Provided herein are methods of identifying a protein capable of binding a ligand, the method comprising: (a) contacting the ligand with two or more samples comprising a plurality of proteins in a solution; (b) separating the proteins bound to the ligand (“bound proteins”) from the proteins that are not bound to the ligand (“unbound proteins”) in each sample; (c) denaturing and digesting the bound proteins to form a plurality of peptides in each sample; (d) quantifying a plurality of molecular features contained in the plurality of peptides in each sample, wherein the molecular features are defined as having a mass to charge ratio, retention time, and peak intensity as measured by mass spectrometry; and (e) ranking the molecular features that exhibit a statistically significant difference in quantity between the samples contacted with the ligand and a sample that is not contacted with the ligand (“statistically significant molecular feature”). |
FILED | Monday, September 25, 2017 |
APPL NO | 16/336079 |
ART UNIT | 1796 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) G01N 33/68 (20130101) G01N 33/94 (20130101) G01N 33/566 (20130101) Original (OR) Class G01N 2030/8831 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567077 | Smith |
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FUNDED BY |
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APPLICANT(S) | OKLAHOMA MEDICAL RESEARCH FOUNDATION (Oklahoma City, Oklahoma) |
ASSIGNEE(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
INVENTOR(S) | Kenneth Smith (Oklahoma City, Oklahoma) |
ABSTRACT | The present invention is directed to particular monoclonal antibodies and fragments thereof that find use in the detection, prevention and treatment of Streptococcus pneumoniae infections. In particular, these antibodies may kill Streptococcus pneumoniae or limit the replication of Streptococcus pneumoniae. Also disclosed are improved methods for producing such monoclonal antibodies. |
FILED | Wednesday, March 02, 2016 |
APPL NO | 15/058814 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/1275 (20130101) C07K 2317/21 (20130101) C07K 2317/33 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/56944 (20130101) Original (OR) Class G01N 2469/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567078 | Wheeler |
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FUNDED BY |
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APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
INVENTOR(S) | Christopher Wheeler (Newbury Park, California) |
ABSTRACT | Described herein are compositions and methods for diagnosing late-onset Alzheimer's disease (LOAD), treating LOAD and assessing efficacy of therapeutic agents used to treat LOAD. |
FILED | Wednesday, August 31, 2016 |
APPL NO | 15/754997 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/06 (20130101) A61K 31/585 (20130101) A61K 33/00 (20130101) A61K 33/04 (20130101) A61K 33/18 (20130101) A61K 33/42 (20130101) A61K 38/00 (20130101) A61K 39/3955 (20130101) A61K 47/641 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 14/4711 (20130101) C07K 14/70539 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 33/56972 (20130101) Original (OR) Class G01N 2333/4709 (20130101) G01N 2800/50 (20130101) G01N 2800/2821 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567081 | Rao et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina); Menarini Silicon Biosystems S.p.A. (Bologna, Italy) |
INVENTOR(S) | Galla Chandra Rao (Princeton Junction, New Jersey); Mark C. Connelly (Doylestown, Pennsylvania); Mariano A. Garcia-Blanco (Hillsborough, North Carolina); Andrew J. Armstrong (Chapel Hill, North Carolina); Rhonda L. Bitting (Durham, North Carolina) |
ABSTRACT | Provided are methods for detecting or isolating circulating tumor cells (CTCs) in a subject. The methods may include detecting the expression of at least one epithelial mesenchymal transition (EMT) biomarker. Further provided are kits for detecting or isolating CTCs. The kits may include antibodies to at least one EMT biomarker. Further provided are methods of predicting the responsiveness of a subject to a cancer drug, methods of targeting delivery of a cancer drug in a subject, methods of providing a cancer prognosis to a subject, and methods for following the progress of cancer in a subject. |
FILED | Friday, November 30, 2018 |
APPL NO | 16/206932 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54326 (20130101) G01N 33/56966 (20130101) G01N 33/57415 (20130101) G01N 33/57434 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 33/57492 (20130101) G01N 2333/47 (20130101) G01N 2333/705 (20130101) G01N 2333/4703 (20130101) G01N 2333/4742 (20130101) G01N 2333/70503 (20130101) G01N 2333/70589 (20130101) G01N 2333/70596 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567085 | Ge et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Ying Ge (Madison, Wisconsin); Song Jin (Madison, Wisconsin); Tania Guardado Alvarez (Madison, Wisconsin); Kyle Brown (Madison, Wisconsin) |
ABSTRACT | The present invention provides photo-cleavable anionic surfactants, particularly 4-hexylphenylazosulfonate (Azo) and sodium 4-hexylphenylazosulfonate derivatives, which can be rapidly degraded upon UV irradiation, for top-down and bottom-up proteomics. These surfactants can effectively solubilize proteins and peptide fragments with performance comparable to sodium dodecyl sulfate (SDS) and are compatible with mass spectrometry analysis of the solubilized proteins and peptide fragments. Top-down proteomic studies using the present photo-cleavable anionic surfactants has allowed the detection of 100-fold more unique proteoforms as compared to controls and has enabled the solubilization of membrane proteins for comprehensive characterization of protein post-translational modifications. In addition, the present photo-cleavable anionic surfactants are also suitable for dissolving polypeptides in bottom-up proteomic experiments including extracellular matrix proteomics, and are suitable as a substitute for SDS in gel electrophoresis. |
FILED | Tuesday, June 04, 2019 |
APPL NO | 16/972881 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 309/15 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/6842 (20130101) G01N 33/6848 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11568044 | Butler et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
INVENTOR(S) | Kevin Butler (Gainesville, Florida); Tuba Yavuz (Gainesville, Florida); Jing Tian (Gainesville, Florida); Grant Hernandez (Gainesville, Florida); Farhaan Fowze (Gainesville, Florida) |
ABSTRACT | Example embodiments provide methods, apparatuses, systems, computing devices, and/or the like for vetting USB device firmware via a USB-specific firmware analysis framework. In one example, a method is provided for analyzing firmware of a Universal Serial Bus (USB) device. The example method includes steps of receiving a firmware image extracted from the USB device, identifying signatures from the firmware image relating to USB operation, and building an expected model of operation of the USB device using the identified signatures and a database of operational information regarding USB devices. The example method further includes the steps of generating a recovered model of operation of the USB device based on the firmware image and the identified signatures, and comparing the recovered model of operation with the expected model of operation to identify unexpected or unknown behaviors. The example method may further include generating a report comprising the identified unexpected or unknown behaviors. |
FILED | Tuesday, March 19, 2019 |
APPL NO | 16/358385 |
ART UNIT | 2491 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 13/4282 (20130101) G06F 21/57 (20130101) G06F 21/552 (20130101) Original (OR) Class G06F 2213/0042 (20130101) G06F 2221/033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569897 | Paramesh et al. |
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FUNDED BY |
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APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Jeyanandh Paramesh (Pittsburgh, Pennsylvania); Susnata Mondal (Pittsburgh, Pennsylvania); L. Richard Carley (Pittsburgh, Pennsylvania) |
ABSTRACT | Disclosed herein is an innovative multi-layer hybrid/digital MIMO architecture that comprises single-stream or fully-connected (FC) multi-stream beamforming tiles (with RF complex-weights) in the first layer, followed by a fully connected (analog/digital) baseband layer. This architecture overcomes the complexity versus spectral-efficiency tradeoffs of existing hybrid MIMO architectures and enables MIMO stream/user scalability, superior energy-efficiency, and spatial-processing flexibility. |
FILED | Monday, February 01, 2021 |
APPL NO | 17/164079 |
ART UNIT | 2632 — Digital Communications |
CURRENT CPC | Transmission H04B 1/16 (20130101) H04B 1/0028 (20130101) H04B 1/0078 (20130101) H04B 7/088 (20130101) Original (OR) Class H04B 7/0413 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 11564579 | Buller |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland) |
ASSIGNEE(S) | U.S. Government, as represented by the Secretary Of the Army (Fort Detrick, Maryland) |
INVENTOR(S) | Mark J. Buller (Douglas, Massachusetts) |
ABSTRACT | The invention in at least one embodiment includes a system and method for detecting and evaluating an adaptive physiological strain index (aPSI) of an individual with a processor and in a further embodiment taking into account the fitness, age and clothing of the individual based upon physiology. The invention in at least one embodiment includes a system and method to calculate the aPSI using physiological measures. In at least one embodiment, the method obtains an individual's skin temperature and heart rate in order to calculate the individual's aPSI. |
FILED | Monday, April 17, 2017 |
APPL NO | 16/072815 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/11 (20130101) A61B 5/441 (20130101) A61B 5/725 (20130101) A61B 5/02055 (20130101) Original (OR) Class A61B 2503/20 (20130101) A61B 2562/0219 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564854 | Cooper et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Aftairs (Washington, District of Columbia) |
INVENTOR(S) | Rory Alan Cooper (Gibsonia, Pennsylvania); Chengshiu Chung (Pittsburgh, Pennsylvania); Garrett G. Grindle (Pittsburgh, Pennsylvania); Rosemarie Cooper (Gibsonia, Pennsylvania); Sathish Andrea Sundaram (Pittsburgh, Pennsylvania) |
ABSTRACT | A wheelchair system includes a wheelchair including a plurality of force sensors including at least three force sensors. A rigid seat pan is placed in contact with each the plurality of force sensors at a different position on the rigid seat pan so that the rigid seat pan does not contact the frame and forces on the rigid seat pan are transferred to the plurality of force sensors. Each of the plurality of force sensors is in communicative connection with a processor system. A memory system is in communicative connection and an interface system is in connection with the processor system and a user interface system in communicative connection with the processor system. Instructions stored on the memory system are executable by the processor system to determine a value of a variable related to a distribution of force on the rigid seat pan over time. |
FILED | Thursday, July 11, 2019 |
APPL NO | 17/259173 |
ART UNIT | 3618 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/128 (20161101) A61G 5/1043 (20130101) A61G 5/1091 (20161101) Original (OR) Class A61G 2203/32 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/30 (20180101) G16H 40/63 (20180101) G16H 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564884 | Reineke et al. |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Theresa Reineke (Vadnais Heights, Minnesota); Zhe Tan (Secaucus, New Jersey); Yaming Jiang (Marlborough, Massachusetts); Mitra S Ganewatta (Ladson, South Carolina); Timothy P. Lodge (Minneapolis, Minnesota) |
ABSTRACT | A compound includes an amphiphilic polymer with a hydrophobic block including monomeric units chosen from alkyl (meth)acrylates, alkyl (meth)acrylamides, and combinations thereof; and a hydrophilic cationic block including monomeric units chosen from alkylamino (meth)acrylates, alkylamino (meth)acrylamides, and combinations thereof. The polymer is in the form of a micelle with a central core derived from the hydrophobic block and shell at least partially surrounding the core. The shell includes a plurality of filamentous arms derived from the hydrophilic block and emanating outward from the core. A biological agent is associated with the arms of the micelle. |
FILED | Wednesday, September 09, 2020 |
APPL NO | 17/015968 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/1075 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 47/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564932 | Szmulewitz et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Russell Z. Szmulewitz (Chicago, Illinois); Suzanne D. Conzen (Park Ridge, Illinois) |
ABSTRACT | Embodiments of the invention are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity. |
FILED | Friday, June 26, 2020 |
APPL NO | 16/913916 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/567 (20130101) Original (OR) Class A61K 31/567 (20130101) A61K 31/569 (20130101) A61K 31/569 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 31/4166 (20130101) A61K 31/4166 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565022 | McKinley et al. |
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FUNDED BY |
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APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
INVENTOR(S) | Todd O. McKinley (Indianapolis, Indiana); James A. Martin (Iowa City, Iowa); Mitchell Coleman (Iowa City, Iowa); Tae-Hong Lim (Coralville, Iowa); Marc Brouillette (Coralville, Iowa) |
ABSTRACT | Compositions comprising a reverse-temperature sensitive hydrogel comprising a biopolymer such as a polysaccharide and a synthetic polymer, and a compound in an amount that reversibly inhibits respiratory enzyme complex I, and methods of using the composition, are provided. |
FILED | Tuesday, May 12, 2020 |
APPL NO | 16/872923 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0024 (20130101) A61K 31/155 (20130101) A61K 31/515 (20130101) A61K 47/34 (20130101) A61K 47/36 (20130101) A61K 47/38 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) Original (OR) Class A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/50 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2300/434 (20130101) A61L 2400/06 (20130101) A61L 2430/24 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 71/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565042 | Bibian et al. |
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FUNDED BY |
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APPLICANT(S) | Stéphane Bibian (Cleveland Heights, Ohio); Tatjana Zikov (Cleveland Heights, Ohio); Sankar Barua (Stow, Ohio) |
ASSIGNEE(S) | NeuroWave Systems Inc. (Cleveland, Ohio) |
INVENTOR(S) | Stéphane Bibian (Cleveland Heights, Ohio); Tatjana Zikov (Cleveland Heights, Ohio); Sankar Barua (Stow, Ohio) |
ABSTRACT | A system and method provides closed-loop sedation, anesthesia, or analgesia by monitoring EEG and automatically adjusting the delivery of sedative, anesthetic, and/or analgesic drugs to maintain that desired level of cortical activity for transportation or evacuation of the injured, and for closed-loop anesthesia during surgical care, and at all echelons of care. |
FILED | Thursday, August 08, 2013 |
APPL NO | 13/962565 |
ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/369 (20210101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 2005/14208 (20130101) A61M 2005/14296 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565107 | Broderick et al. |
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FUNDED BY |
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APPLICANT(S) | Kate Broderick (San Diego, California); Jay McCoy (San Diego, California); Stephen V. Kemmerrer (San Diego, California); Feng Lin (San Diego, California); Rune Kjeken (Oslo, Norway) |
ASSIGNEE(S) | Inovio Pharmaceuticals, Inc. (Plymouth Meeting, Pennsylvania) |
INVENTOR(S) | Kate Broderick (San Diego, California); Jay McCoy (San Diego, California); Stephen V. Kemmerrer (San Diego, California); Feng Lin (San Diego, California); Rune Kjeken (Oslo, Norway) |
ABSTRACT | A novel electroporation device for the delivery of vaccines that is both effective in generating a protective immune response and tolerable delivery to a subject (or near painless); and also methods of using same device to vaccinate a subject against a variety of infectious diseases and types of cancer in a near painless. |
FILED | Tuesday, March 01, 2011 |
APPL NO | 13/581702 |
ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 2039/53 (20130101) A61K 2039/54 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) Original (OR) Class A61N 1/0502 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565139 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Linda S Lee (West Lafayette, Indiana); Jenny E Zenobio (Arlington, Massachusetts) |
ABSTRACT | The present application relates to a novel method for reductive degradation of perfluoroalkyl-containing compounds, such as perfluoroalkyl sulfonates, by activated carbon (AC) supported zero valent iron-nickle nanoparticles (nNi0Fe0). |
FILED | Thursday, April 29, 2021 |
APPL NO | 17/244219 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/34 (20130101) Original (OR) Class A62D 3/37 (20130101) A62D 2101/22 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/755 (20130101) Reclamation of Contaminated Soil B09C 1/002 (20130101) B09C 1/06 (20130101) B09C 1/08 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/283 (20130101) C02F 1/705 (20130101) C02F 2101/36 (20130101) C02F 2103/06 (20130101) C02F 2305/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565230 | Jensen et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Klavs F. Jensen (Lexington, Massachusetts); Timothy F. Jamison (Cambridge, Massachusetts); Allan S. Myerson (Cambridge, Massachusetts); Jean-Christophe M. Monbaliu (Esneux, Belgium); Mohsen Behnam (Worcester, Massachusetts); Shin Yee Wong (Singapore, Singapore); Nopphon Weeranoppanant (Suphanburi, Thailand); Eve Marie Revalor (Rognes, France); Torsten Stelzer (Old San Juan, Puerto Rico); Jie Chen (Evanston, Illinois); Andrea Adamo (Cambridge, Massachusetts); David R. Snead (Atlanta, Georgia); Ping Zhang (Somerville, Massachusetts) |
ABSTRACT | Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product. |
FILED | Monday, August 10, 2020 |
APPL NO | 16/988827 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/14 (20130101) A61K 31/167 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/004 (20130101) Original (OR) Class B01J 19/18 (20130101) B01J 19/0093 (20130101) B01J 2219/0002 (20130101) B01J 2219/0004 (20130101) B01J 2219/00011 (20130101) B01J 2219/0081 (20130101) B01J 2219/00795 (20130101) B01J 2219/00799 (20130101) B01J 2219/00806 (20130101) B01J 2219/00813 (20130101) B01J 2219/00817 (20130101) B01J 2219/00822 (20130101) B01J 2219/00831 (20130101) B01J 2219/00833 (20130101) B01J 2219/00835 (20130101) B01J 2219/00871 (20130101) B01J 2219/00873 (20130101) B01J 2219/00889 (20130101) B01J 2219/00907 (20130101) B01J 2219/00909 (20130101) B01J 2219/00918 (20130101) B01J 2219/00986 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565256 | Reiserer et al. |
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FUNDED BY |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
INVENTOR(S) | Ronald S. Reiserer (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); Philip C. Samson (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Michael Geuy (Nashville, Tennessee); Lisa J. McCawley (Nashville, Tennessee); John P. Wikswo (Brentwood, Tennessee) |
ABSTRACT | Microfluidic systems, pumps, valves and applications of the same are provided. The microfluidic system may be a pump or a valve having a fluidic chip and an actuator controlling the opening and closing of the fluidic channel in the fluidic chip. The actuator may be disposed to tilt from the fluidic chip, forming a tilted-rotor peristaltic pump. Alternatively, the actuator may be a rolling ball actuator, and different fluidic chips may be used in different applications. For example, the fluidic chip may be a spiral pump chip having spiral channels, a rotary peristaltic pump chip having multiple output channels, or a multi-port valve chip having one port interconnected with multiple different ports. An analytical valve chip may switchably interconnect bioreactor and rinse/calibration input channels to sensor and waste output channels. The actuator of a random-access valve can move from one valve position to another without opening or closing intermediate ones. |
FILED | Monday, June 29, 2020 |
APPL NO | 17/623350 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) Original (OR) Class B01L 2300/123 (20130101) B01L 2300/0627 (20130101) B01L 2400/0644 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/1261 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/163 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565759 | Rudakevych |
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FUNDED BY |
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APPLICANT(S) | Teledyne FLIR Detection, Inc. (Stillwater, Oklahoma) |
ASSIGNEE(S) | Teledyne FLIR Detection, Inc. (Stillwater, Oklahoma) |
INVENTOR(S) | Pavlo E. Rudakevych (San Luis Obispo, California) |
ABSTRACT | A mobile robot includes a robot chassis having a forward end, a rearward end and a center of gravity. The robot includes a driven support surface to propel the robot and first articulated arm rotatable about an axis located rearward of the center of gravity of the robot chassis. The arm is pivotable to trail the robot, rotate in a first direction to raise the rearward end of the robot chassis while the driven support surface propels the chassis forward in surmounting an obstacle, and to rotate in a second opposite direction to extend forward beyond the center of gravity of the robot chassis to raise the forward end of the robot chassis and invert the robot endwise. |
FILED | Monday, May 04, 2020 |
APPL NO | 16/865536 |
ART UNIT | 3611 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Motor Vehicles; Trailers B62D 55/06 (20130101) B62D 55/075 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565787 | Neely et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | Jared Neely (Troy, Ohio); James Joo (Centerville, Ohio) |
ABSTRACT | The present disclosure defines a morphing airfoil having a dynamic flexible anisotropic skin system that is capable of carrying high level aerodynamic (or fluid) pressure loads over a structural surface. The structural surface can morph and bend in response to control inputs to change a lift force without separate movable control surfaces. The anisotropic skin is attached to underlying active and compliant structures. A control system causes the underlying support structure to move to a desired location which in turn causes the skin to bend and/or flex without exceeding a stress threshold and thus vary the lift profile along a span of the airfoil. |
FILED | Tuesday, December 22, 2020 |
APPL NO | 17/130560 |
ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 3/26 (20130101) B64C 3/48 (20130101) Original (OR) Class B64C 2003/445 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565788 | Witt |
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FUNDED BY |
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APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
ASSIGNEE(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
INVENTOR(S) | Jonathan Witt (Fort Worth, Texas) |
ABSTRACT | According to an aspect, a pivoting sail fairing system includes a rotatable fairing, for rotation about a first axis of rotation of an aircraft, that includes a housing that defines a compartment arranged inward from the housing, the housing including a first orifice on a first surface and a second orifice on a second surface of the housing, and a first actuator mounted on a surface of the compartment inward from the housing. |
FILED | Thursday, March 05, 2020 |
APPL NO | 16/809936 |
ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 7/00 (20130101) Original (OR) Class B64C 27/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565802 | Acee et al. |
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FUNDED BY |
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APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
INVENTOR(S) | Aaron Alexander Acee (Flower Mound, Texas); Andrew Thomas Carter (Richland Hills, Texas); Michael Scott Seifert (Southlake, Texas); Shahryar Fotovati (North Richland Hills, Texas) |
ABSTRACT | A rotor system for a rotorcraft includes a rotor hub having a plurality of blade grips coupled thereto. Each blade grip has a rotor blade coupled thereto. A fairing is disposed at least partially around the rotor hub. Each of a plurality of lead-lag dampers is coupled to at least a respective one of the blade grips. Each lead-lag damper has a damper heat exchanger and a fluid pump operably associated therewith. A fairing heat exchanger is in fluid communication with the damper heat exchangers and the fluid pumps. Each lead-lag damper is configured to drive the respective fluid pump responsive to damping operations to pump a cooling fluid from the respective damper heat exchanger to the fairing heat exchanger. |
FILED | Thursday, January 21, 2021 |
APPL NO | 17/154650 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Aeroplanes; Helicopters B64C 27/51 (20130101) Original (OR) Class Springs; Shock-absorbers; Means for Damping Vibration F16F 9/42 (20130101) F16F 13/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565936 | George et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado); DRS NETWORK and IMAGING SYSTEMS, LLC (Dallas, Texas) |
ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado); DRS Network and Imaging Systems, LLC (Dallas, Texas) |
INVENTOR(S) | Steven M. George (Boulder, Colorado); Victor M. Bright (Boulder, Colorado); Joseph J. Brown (Honolulu, Hawaii); Jonas Gertsch (Boulder, Colorado); Nathan Thomas Eigenfeld (Boulder, Colorado); George Skidmore (Richardson, Texas) |
ABSTRACT | The present invention relates to the unexpected discovery of novel methods of preparing nanodevices and/or microdevices with predetermined patterns. In one aspect, the methods of the invention allow for engineering structures and films with continuous thickness equal to or less than 50 nm. |
FILED | Thursday, May 25, 2017 |
APPL NO | 16/303612 |
ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 7/24 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00531 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/01 (20130101) C23C 16/403 (20130101) C23C 16/45555 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/311 (20130101) H01L 21/3065 (20130101) H01L 21/30655 (20130101) H01L 21/31122 (20130101) H01L 21/31144 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566009 | Chavez et al. |
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FUNDED BY |
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APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico); The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico); The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | David Chavez (Los Alamos, New Mexico); Jesse Sabatini (Bel Air, Maryland); Pablo Guzmán (Bel Air, Maryland); Leah Wingard (Landenberg, Pennsylvania); Eric Johnson (Millington, Maryland) |
ABSTRACT | Disclosed herein are embodiments of an energetic compound and methods of making and using the same. Energetic compound embodiments disclosed herein exhibit physical and chemical properties that facilitate their use in various applications, such as high energy propellant plasticizers, melt-castable explosives, and the like. Efficient and safe method embodiments for making the disclosed energetic compound embodiments are described herein. |
FILED | Friday, May 15, 2020 |
APPL NO | 16/875544 |
ART UNIT | 1699 — Organic Chemistry |
CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 25/34 (20130101) Heterocyclic Compounds C07D 271/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566115 | Deravi et al. |
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FUNDED BY |
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APPLICANT(S) | Northeastern University (Boston, Massachusetts); U.S. Govt. as Represented by the Sec. of the Army (Natick, Massachusetts) |
ASSIGNEE(S) | Northeastern University (Boston, Massachusetts); US Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
INVENTOR(S) | Leila Deravi (Cambridge, Massachusetts); Camille A. Martin (Boston, Massachusetts); Amrita Kumar (Cambridge, Massachusetts); Richard M. Osgood, III (Winchester, Massachusetts) |
ABSTRACT | Biologically-inspired compositions, including color changing compositions, and corresponding embodiments such as sensors, textile materials, coatings and films, are provided which typically include a solid, transparent and nondegradable matrix. The matrix contains a plurality of (i) synthetic particles having a size in the micrometer or nanometer range, each synthetic particle including one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45, the aggregates having a size larger than about 100 nm; or (ii) submicrometer natural particles extracted and purified from homogenized tissue. |
FILED | Tuesday, September 25, 2018 |
APPL NO | 16/141758 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 5/046 (20130101) Original (OR) Class C08J 2323/06 (20130101) C08J 2367/00 (20130101) C08J 2375/04 (20130101) C08J 2377/00 (20130101) C08J 2425/06 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/36 (20130101) C08K 5/0041 (20130101) C08K 5/357 (20130101) C08K 2003/2241 (20130101) C08K 2003/2265 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566242 | Kogut et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
INVENTOR(S) | Igor Kogut (Aurora, Colorado); Dennis R. Roop (Greenwood Village, Colorado); Ganna Bilousova (Aurora, Colorado); Patrick S. McGrath (Denver, Colorado) |
ABSTRACT | The present disclosure relates to methods and compositions for reprogramming cells to a pluripotent state. In particular, it relates to an integration- and feeder cell-free method for reprogramming primary human fibroblast cells to induced pluripotent stem cells (iPSCs). |
FILED | Friday, April 20, 2018 |
APPL NO | 15/958965 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 35/28 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0652 (20130101) C12N 5/0696 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2310/141 (20130101) C12N 2330/31 (20130101) C12N 2500/60 (20130101) C12N 2501/65 (20130101) C12N 2501/115 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566268 | Clarke et al. |
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FUNDED BY |
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APPLICANT(S) | ISIS INNOVATION LTD (Oxfordshire, United Kingdom); GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
ASSIGNEE(S) | GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); OXFORD UNIVERSITY INNOVATION LIMITED (Oxford, United Kingdom) |
INVENTOR(S) | Kieran Clarke (Oxford, United Kingdom); Richard Lewis Veech (Rockville, Maryland); M. Todd King (Rockville, Maryland) |
ABSTRACT | Embodiments of the present invention are directed to processes for the production of (R)-3-hydroxybutyl (R)-3-hydroxybyrate. Poly (R)-3-hydroxybyrate is transesterified with an alcohol, to form a first ester portion and a second ester portion. The first ester portion is reduced to the diol to form a diol portion and the diol portion is reacted with the second ester portion to produce (R)-3-hydroxybutyl (R)-3-hydroxybyrate. |
FILED | Friday, March 14, 2014 |
APPL NO | 14/213713 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 29/147 (20130101) C07C 29/147 (20130101) C07C 31/207 (20130101) C07C 67/03 (20130101) C07C 67/03 (20130101) C07C 69/675 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566291 | Myers et al. |
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FUNDED BY |
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APPLICANT(S) | HudsonAlpha Institute for Biotechnology (Huntsville, Alabama); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
ASSIGNEE(S) | HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY (Huntsville, Alabama); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
INVENTOR(S) | Richard M. Myers (Huntsville, Alabama); James D. Brooks (Stanford, California); Marie K. Kirby (Huntsville, Alabama) |
ABSTRACT | The present disclosure provides for and relates to the identification of novel biomarkers for diagnosis and prognosis of prostate cancer or the biochemical reoccurrence of prostate cancer. The biomarkers of the invention show altered methylation levels of certain CpG loci relative to normal prostate tissue, as set forth. |
FILED | Thursday, March 13, 2014 |
APPL NO | 14/774227 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/154 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566349 | Dunn et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Ryan M. Dunn (Belcamp, Maryland); Kevin R. Hart (Milwaukee, Wisconsin); Eric D. Wetzel (Bel Air, Maryland) |
ABSTRACT | A polymer body includes a first thermoplastic polymer, and a second thermoplastic polymer. The first thermoplastic polymer and the second thermoplastic polymer form a continuous solid structure. The first thermoplastic polymer forms an external supporting structure that at least partially envelops the second thermoplastic polymer. A first flow temperature of the first thermoplastic polymer is at least 10° C. higher than a second flow temperature of the second thermoplastic polymer. The first thermoplastic polymer may be removable by exposure to a selective solvent. |
FILED | Tuesday, August 11, 2020 |
APPL NO | 16/990164 |
ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/02 (20130101) B29C 48/16 (20190201) B29C 48/91 (20190201) B29C 55/00 (20130101) B29C 64/106 (20170801) B29C 64/118 (20170801) B29C 71/0009 (20130101) B29C 2071/022 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2033/12 (20130101) B29K 2055/02 (20130101) B29K 2069/00 (20130101) B29K 2105/08 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/731 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/24 (20130101) D01D 5/30 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 8/00 (20130101) D01F 8/10 (20130101) D01F 8/14 (20130101) Original (OR) Class D01F 8/18 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2321/08 (20130101) D10B 2321/10 (20130101) D10B 2331/04 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566529 | Duffen et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
INVENTOR(S) | Shawn Patrick Duffen (Windham, New Hampshire); Donald Brett DeSander (Arlington, Massachusetts); Victor Hugo Silva Correia (Milton Mills, New Hampshire) |
ABSTRACT | A turbomachinery component with a surface that includes a bounded wear coat, the component includes: a body; a contact surface defined by the body; a recess extending into the body and communicating with the contact surface; and a wear coat positioned in the recess. |
FILED | Tuesday, August 22, 2017 |
APPL NO | 15/683332 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/225 (20130101) Original (OR) Class F01D 5/286 (20130101) F01D 5/288 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/90 (20130101) F05D 2240/307 (20130101) F05D 2250/131 (20130101) F05D 2250/141 (20130101) F05D 2300/20 (20130101) F05D 2300/175 (20130101) F05D 2300/506 (20130101) F05D 2300/611 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566898 | Wen et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Haoran Wen (Atlanta, Georgia); Farrokh Ayazi (Atlanta, Georgia) |
ABSTRACT | A bulk acoustic wave resonator apparatus includes a resonator member, at least one anchor structure coupling the resonator member to a substrate, and a comb-drive element connected to the resonator member. The comb-drive element includes first comb fingers protruding from the resonator member, and second comb fingers of a different material than the first comb fingers interdigitated with the first comb fingers to define sub-micron capacitive gaps therebetween. Respective sidewalls of the first comb fingers are oppositely-tapered relative to respective sidewalls of the second comb fingers along respective lengths thereof, such that operation of the comb-drive element varies the sub-micron capacitive gaps at the respective sidewalls thereof. Respective tuning electrodes, which are slanted at respective angles parallel to an angle of respective sidewalls of the resonator member, may also be provided for quadrature tuning between different resonance modes of the resonator member. Related devices and fabrication methods are also discussed. |
FILED | Wednesday, September 01, 2021 |
APPL NO | 17/463689 |
ART UNIT | 2853 — Printing/Measuring and Testing |
CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/033 (20130101) B81B 2203/0136 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5677 (20130101) G01C 19/5684 (20130101) G01C 19/5698 (20130101) Original (OR) Class G01C 19/5719 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/02228 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566918 | Claytor et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Kevin E. Claytor (Columbia, Maryland); David M. Hull (Adelphi, Maryland) |
ABSTRACT | A non-contact power meter system for measuring power in an energized cable is provided. It includes: at least one electric field sensor; a plurality of magnetic field sensors, wherein the at least two magnetic field sensors together are configured to measure a magnetic field in a tangential direction and a radial direction with respect the energized cable measured; and a processor, which receives measurement signals from the various sensors, and is configured to measure power in the energized cable. A method of determining twist in an energized cable using non-contact power meter system(s) is also provided. |
FILED | Thursday, August 13, 2020 |
APPL NO | 16/992174 |
ART UNIT | 2868 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/145 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 21/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566944 | Stone |
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FUNDED BY |
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APPLICANT(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
ASSIGNEE(S) | Wavefront Research, Inc. (Northhampton, Pennsylvania) |
INVENTOR(S) | Thomas W. Stone (Hellertown, Pennsylvania) |
ABSTRACT | Systems that enable observing celestial bodies during daylight or in under cloudy conditions. |
FILED | Monday, August 12, 2019 |
APPL NO | 16/537814 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 3/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/0488 (20130101) G01J 1/4228 (20130101) G01J 5/10 (20130101) Original (OR) Class G01J 5/0802 (20220101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/70 (20130101) G01S 3/78 (20130101) G01S 3/7867 (20130101) Optical Elements, Systems, or Apparatus G02B 5/208 (20130101) G02B 23/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567054 | Welle |
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FUNDED BY |
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APPLICANT(S) | US Government by the Secretary of the Air Force (Wright Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | Eric Welle (Niceville, Florida) |
ABSTRACT | A shaped lens for minimizing differences in time of arrival at the output surface of an explosive assembly. The lens is plano-convex with the convex shape oriented towards the explosive charge. The lens becomes monotonically thicker as the center of the lens is radially approached from the edge, according to a formula accounting for the detonation velocity of the explosive and velocity of the shockwave through the lens. The lens is preferably incorporated into a test fixture using a liquid explosive, such as nitromethane. The test fixture may be assembled on site, at the test location. |
FILED | Friday, July 09, 2021 |
APPL NO | 17/305589 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 1/024 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/227 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567081 | Rao et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina); Menarini Silicon Biosystems S.p.A. (Bologna, Italy) |
INVENTOR(S) | Galla Chandra Rao (Princeton Junction, New Jersey); Mark C. Connelly (Doylestown, Pennsylvania); Mariano A. Garcia-Blanco (Hillsborough, North Carolina); Andrew J. Armstrong (Chapel Hill, North Carolina); Rhonda L. Bitting (Durham, North Carolina) |
ABSTRACT | Provided are methods for detecting or isolating circulating tumor cells (CTCs) in a subject. The methods may include detecting the expression of at least one epithelial mesenchymal transition (EMT) biomarker. Further provided are kits for detecting or isolating CTCs. The kits may include antibodies to at least one EMT biomarker. Further provided are methods of predicting the responsiveness of a subject to a cancer drug, methods of targeting delivery of a cancer drug in a subject, methods of providing a cancer prognosis to a subject, and methods for following the progress of cancer in a subject. |
FILED | Friday, November 30, 2018 |
APPL NO | 16/206932 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54326 (20130101) G01N 33/56966 (20130101) G01N 33/57415 (20130101) G01N 33/57434 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 33/57492 (20130101) G01N 2333/47 (20130101) G01N 2333/705 (20130101) G01N 2333/4703 (20130101) G01N 2333/4742 (20130101) G01N 2333/70503 (20130101) G01N 2333/70589 (20130101) G01N 2333/70596 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567100 | Reinke |
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FUNDED BY |
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APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
INVENTOR(S) | John Reinke (Plymouth, Minnesota) |
ABSTRACT | The disclosure describes techniques to adjust the geometry of a pendulous proof mass VBA to operate with sufficient signal-to-noise performance while avoiding nonlinear mechanical coupling at specified frequencies. The techniques of this disclosure include adding anchor support flexures to a resonator connection structure, adjusting shape, thickness, and the material of VBA components and of the VBA support structure to both control the frequency of any mechanical resonant modes and to adjust the mechanical mode frequencies away from desired operating frequencies and, in some examples, away from harmonics of desired operating frequencies. |
FILED | Friday, August 28, 2020 |
APPL NO | 17/006506 |
ART UNIT | 2861 — Printing/Measuring and Testing |
CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 7/007 (20130101) B81B 2201/0235 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/097 (20130101) Original (OR) Class G01P 15/125 (20130101) G01P 2015/0854 (20130101) G01P 2015/0882 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/08 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/2473 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567234 | Alfano et al. |
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FUNDED BY |
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APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
INVENTOR(S) | Robert R. Alfano (Bronx, New York); Daniel Nolan (Painted Post, New York) |
ABSTRACT | Structured beams, Bessel beams, Laguerre Gaussian beams, and focused Gaussian are used as a natural waveguide and its group velocity can be subluminal (slower than the speed of light) as compared to a Gaussian beam in free space. A free space dispersion relation for a Bessel beam, i.e., the dependence of its wavenumber on its angular frequency, is outlined from which the Bessel beam's subliminal group velocity is derived. For reasonable conditions a Bessel light beam has associated parameters that allow slowing near a critical frequency. The application of Bessel beams for a natural optical buffer in free space is presented. Optical transitions and selection rules in materials are altered by structured light carrying orbital angular momentum (OAM). Nano antennas are used to enhance the interactions of structured light. |
FILED | Thursday, June 06, 2019 |
APPL NO | 16/433764 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) Original (OR) Class G02B 6/2861 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567341 | Braunreiter et al. |
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FUNDED BY |
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APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
INVENTOR(S) | Dennis Braunreiter (San Diego, California); Aaron Stonely (McKinney, Texas); Daniel Young (Allen, Texas) |
ABSTRACT | A system includes a high energy laser (HEL) configured to transmit a HEL beam aimed at a first location on an airborne target. The system also includes a beacon illuminator laser (BIL) configured to transmit a BIL beam aimed at a second location on the target, wherein the second location is offset from the first location. The system also includes at least one fast steering mirror (FSM) configured to steer the BIL beam to be spatially and angularly offset from the HEL beam. The system also includes at least one Coudé path FSM configured to simultaneously receive both the HEL beam and the BIL beam and steer the HEL beam and the BIL beam to correct for atmospheric jitter of the HEL beam and the BIL beam while maintaining the offset of the BIL beam from the HEL beam. |
FILED | Tuesday, September 03, 2019 |
APPL NO | 16/559136 |
ART UNIT | 2883 — Optics |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/90 (20200101) Optical Elements, Systems, or Apparatus G02B 26/0816 (20130101) G02B 27/648 (20130101) Original (OR) Class Transmission H04B 10/1125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567746 | Baskaran et al. |
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FUNDED BY |
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APPLICANT(S) | QUALCOMM TECHNOLOGIES, INC. (San Diego, California) |
ASSIGNEE(S) | Qualcomm Technologies Inc. (San Diego, California) |
INVENTOR(S) | Muthu M. Baskaran (Old Tappan, New Jersey); Thomas Henretty (Brooklyn, New York); Richard A. Lethin (New York, New York); Benoit J. Meister (New York, New York) |
ABSTRACT | In a sequence of major computational steps or in an iterative computation, a stencil amplifier can increase the number of data elements accessed from one or more data structures in a single major step or iteration, thereby decreasing the total number of computations and/or communication operations in the overall sequence or the iterative computation. Stencil amplification, which can be optimized according to a specified parameter such as compile time, rune time, code size, etc., can improve the performance of a computing system executing the sequence or the iterative computation in terms of run time, memory load, energy consumption, etc. The stencil amplifier typically determines boundaries, to avoid erroneously accessing data elements not present in the one or more data structures. |
FILED | Monday, July 13, 2020 |
APPL NO | 16/927016 |
ART UNIT | 2198 — Optics |
CURRENT CPC | Electric Digital Data Processing G06F 8/4434 (20130101) G06F 8/4441 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567855 | Fletcher et al. |
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FUNDED BY |
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APPLICANT(S) | Two Six Labs, LLC (Arlington, Virginia) |
ASSIGNEE(S) | Two Six Labs, LLC (Arlington, Virginia) |
INVENTOR(S) | Austin Fletcher (Keego Harbor, Michigan); Daniel Su (Arlington, Virginia); Bradley Boccuzzi (Arlington, Virginia) |
ABSTRACT | An automated fault injection testing and analysis approach drives fault injection into a processor driven instruction sequence to quantify and define susceptibility to external fault injections for manipulating instruction execution and control flow of a set of computer instructions. A fault injection such as a voltage or electromagnetic pulse directed at predetermined locations on a processor (Central Processing Unit, or CPU) alters a result of a processor instruction to change values or execution paths. One or more quantified injections define an injection chain that causes a predictable or repeatable deviant result from an expected execution path through the code executed by the processor. Based on accumulation of fault injections and results, a repeatable injection chain and probability identifies an external action taken on a processing device to cause unexpected results that differ from an expected execution of a program or set of computer instructions. |
FILED | Wednesday, September 09, 2020 |
APPL NO | 17/015778 |
ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 11/263 (20130101) G06F 11/277 (20130101) G06F 11/3644 (20130101) Original (OR) Class G06F 11/3692 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11568113 | Chakrabarty et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
INVENTOR(S) | Krishnendu Chakrabarty (Durham, North Carolina); Sanmitra Banerjee (Durham, North Carolina) |
ABSTRACT | Variation-aware delay fault testing suitable for carbon nanotube field-effect transistor circuits can be accomplished using an electronic design automation tool that performs long path selection by generating random variation scenarios, wherein a random variation scenario (RVS) is an instance of an input netlist where values for a set of process parameters for each gate are chosen from a set of values for each process parameter of the set of process parameters for that gate, the set of values being sampled from a distribution of that particular process parameter for that gate and includes a nominal value for that particular process parameter; calculating a total delay through a path for each RVS; and selecting at least two paths having highest total delays for each fault site under random variations of the RVSs. Delay test patterns can then be generated for the selected paths. |
FILED | Wednesday, August 25, 2021 |
APPL NO | 17/411346 |
ART UNIT | 2851 — Printing/Measuring and Testing |
CURRENT CPC | Electric Digital Data Processing G06F 30/31 (20200101) Original (OR) Class G06F 30/3308 (20200101) G06F 2117/06 (20200101) |
VIEW PATENT | @ USPTO: Full Text PDF |
11568221 — Artificial neuron synaptic weights implemented with variable dissolvable conductive paths
US 11568221 | Cambou et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona); Government of the United States of America, as represented by the Secretary of the Air Force (Rome, New York) |
ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona); GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE AIRFORCE (Rome, New York) |
INVENTOR(S) | Bertrand F Cambou (Flagstaff, Arizona); Donald A. Telesca, Jr. (Whitesboro, New York); Brayden Cole David Villa (Flagstaff, Arizona) |
ABSTRACT | A low-power, controllable, and reconfigurable method to control weights in model neurons in an Artificial Neural Network is disclosed. Memristors are utilized as adjustable synapses, where the memristor resistance reflects the synapse weight. The injection of extremely small electric currents (a few nanoamperes) in each cell forces the resistance to drop abruptly by several orders of magnitudes due to the formation of a conductive path between the two electrodes. These conductive paths dissolve as soon as the current injection stops, and the cells return to their initial state. A repeated injection of currents into the same cell results in an almost identical effect in resistance drop. Different, stable resistance values in each cell can be controllably achieved by injecting different current values. |
FILED | Friday, March 08, 2019 |
APPL NO | 16/297441 |
ART UNIT | 2125 — AI & Simulation/Modeling |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) Original (OR) Class G06N 3/0481 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11568909 | Victora et al. |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Randall H. Victora (New Brighton, Minnesota); Roy C Bell (Minneapolis, Minnesota) |
ABSTRACT | An example article includes a composite free layer and a conductive channel. The composite free layer includes a high-anisotropy ferromagnetic layer, a non-magnetic transition metal layer adjacent to the high anisotropy ferromagnetic layer, and an ultra-low damping magnetic insulator. The non-magnetic transition metal layer is between the ultra-low damping magnetic insulator and the high-anisotropy ferromagnetic layer. An example spin-orbit torque (SOT) stack may include the example article. Techniques for forming and switching example articles and SOT stacks are described. |
FILED | Friday, September 10, 2021 |
APPL NO | 17/447354 |
ART UNIT | 2898 — Semiconductors/Memory |
CURRENT CPC | Static Stores G11C 11/161 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/222 (20130101) H01L 43/08 (20130101) H01L 43/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569077 | McBride et al. |
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FUNDED BY |
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APPLICANT(S) | SRI International (Menlo Park, California) |
ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
INVENTOR(S) | Sterling Eduardo McBride (Princeton, New Jersey); Joey J. Michalchuk (Lambertville, New Jersey); Christopher E. Holland (San Jose, California); Ashish Chaudhary (Safety Harbor, Florida); Winston K. Chan (Princeton, New Jersey) |
ABSTRACT | The disclosure includes an outer electrode and an inner electrode. The outer electrode defines an inner volume and is configured to receive injected electrons through at least one aperture. The inner electrode positioned in the inner volume. The outer electrode and inner electrode are configured to confine the received electrons in orbits around the inner electrode in response to an electric potential between the outer electrode and the inner electrode. The apparatus does not include a component configured to generate an electron-confining magnetic field. |
FILED | Wednesday, July 11, 2018 |
APPL NO | 16/629528 |
ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 3/40 (20130101) B03C 3/41 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 37/02 (20130101) F04B 37/14 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 21/34 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 1/30 (20130101) H01J 1/304 (20130101) H01J 9/02 (20130101) H01J 41/00 (20130101) H01J 41/04 (20130101) H01J 41/12 (20130101) H01J 41/14 (20130101) H01J 41/16 (20130101) H01J 41/20 (20130101) Original (OR) Class Dynamo-electric Machines H02K 44/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569182 | Piedra et al. |
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FUNDED BY |
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APPLICANT(S) | Analog Devices, Inc. (Norwood, Massachusetts) |
ASSIGNEE(S) | Analog Devices, Inc. (Norwood, Massachusetts) |
INVENTOR(S) | Daniel Piedra (Cambridge, Massachusetts); James G. Fiorenza (Carlisle, Massachusetts); Puneet Srivastava (Wilmington, Massachusetts); Andrew Proudman (Medford, Massachusetts); Kenneth Flanders (Reading, Massachusetts); Denis Michael Murphy (Concord, Massachusetts); Leslie P. Green (Framingham, Massachusetts); Peter R. Stubler (Andover, Massachusetts) |
ABSTRACT | Gallium nitride-based monolithic microwave integrated circuits (MMICs) can comprise aluminum-based metals. Electrical contacts for gates, sources, and drains of transistors can include aluminum-containing metallic materials. Additionally, connectors, inductors, and interconnect devices can also comprise aluminum-based metals. The gallium-based MMICs can be manufactured in complementary metal oxide semiconductor (CMOS) facilities with equipment that produces silicon-based semiconductor devices. |
FILED | Thursday, October 01, 2020 |
APPL NO | 17/061075 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/8252 (20130101) H01L 21/28575 (20130101) H01L 23/66 (20130101) Original (OR) Class H01L 23/481 (20130101) H01L 23/53214 (20130101) H01L 27/0605 (20130101) H01L 27/0629 (20130101) H01L 28/60 (20130101) H01L 29/205 (20130101) H01L 29/452 (20130101) H01L 29/2003 (20130101) H01L 29/4175 (20130101) H01L 29/7786 (20130101) H01L 29/66462 (20130101) H01L 2223/6616 (20130101) H01L 2223/6683 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569667 | Robinson et al. |
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FUNDED BY |
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APPLICANT(S) | Galvion Soldier Power, LLC (Southborough, Massachusetts) |
ASSIGNEE(S) | GALVION SOLDIER POWER, LLC (Southborough, Massachusetts) |
INVENTOR(S) | Philip T. Robinson (Harvard, Massachusetts); Seth M. Dziengeleski (Southbridge, Massachusetts); James D. Kazmierczak (Marlborough, Massachusetts); David J. Holigan (Atkinson, New Hampshire) |
ABSTRACT | Various aspects of invention provide portable power manager operating methods. One aspect of the invention provides a method for operating a power manager having a plurality of device ports for connecting with external power devices and a power bus for connecting with each device port. The method includes: disconnecting each device port from the power bus when no external power device is connected to the device port; accessing information from newly connected external power devices; determining if the newly connected external power devices can be connected to the power bus without power conversion; if not, determining if the newly connected external power devices can be connected to the power bus over an available power converter; and if so, configuring the available power converter for suitable power conversion. |
FILED | Monday, February 14, 2022 |
APPL NO | 17/671184 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Electric Digital Data Processing G06F 1/263 (20130101) G06F 1/266 (20130101) G06F 1/3287 (20130101) G06F 13/4022 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 4/00 (20130101) H02J 5/00 (20130101) H02J 7/02 (20130101) H02J 7/0013 (20130101) H02J 7/00036 (20200101) H02J 7/00045 (20200101) H02J 7/00047 (20200101) Original (OR) Class H02J 7/0048 (20200101) H02J 7/0068 (20130101) H02J 2310/22 (20200101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/04 (20130101) H02M 5/04 (20130101) H02M 7/04 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569684 | White et al. |
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FUNDED BY |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
INVENTOR(S) | Carson R. White (Agoura Hills, California); Walter S. Wall (Calabasas, California); Christopher P. Henry (Thousand Oaks, California); Christopher S. Roper (Santa Monica, California); James H. Schaffner (Chatsworth, California); Ignacio Ramos (Santa Monica, California) |
ABSTRACT | An energy conversion device disposed in series with an RF driver circuit and an RF antenna, the energy conversion device being arranged to convert a portion of available RF power from the RF driver circuit into a different form of energy (direct current, thermal, or higher frequency electromagnetic waves such as light) which is converted, if needed, to DC and stored in an energy storage device coupled with the RF driver circuit for supplying recycled electrical energy thereto. The RF antenna may be an electrically small antenna and thus a antenna matching network may be provided between the RF driver circuit and the RF antenna. The energy conversion device may comprise, for example, (i) a transformer in combination with a rectifying circuit, (ii) a full wave rectifier, (iii) a half wave rectifier, (iv) a heat and/or light producing device, an energy converter (such as a generator) or a combination of the foregoing. |
FILED | Tuesday, May 05, 2020 |
APPL NO | 16/867411 |
ART UNIT | 2876 — Optics |
CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 29/14 (20130101) Antennas, i.e Radio Aerials H01Q 1/2225 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/00 (20130101) H02J 50/005 (20200101) Original (OR) Class H02J 50/27 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569701 | Cao |
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FUNDED BY |
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APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
INVENTOR(S) | Yang Cao (Glastonbury, Connecticut) |
ABSTRACT | An insulating composition having a polymer resin, a nanoclay, and one or more nanofillers. The insulating composition has a thermal conductivity of greater than about 0.8 W/mK, a dielectric constant of less than about 5, a dissipation factor of less than about 3%, and a breakdown strength of greater than about 1,000V/mil. The insulating composition has an endurance life of at least 400 hours at 310 volts per mil. |
FILED | Tuesday, August 13, 2019 |
APPL NO | 16/539526 |
ART UNIT | 2847 — Electrical Circuits and Systems |
CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/12 (20130101) H01B 3/40 (20130101) H01B 3/46 (20130101) H01B 3/305 (20130101) H01B 3/306 (20130101) H01B 3/426 (20130101) H01B 3/427 (20130101) Dynamo-electric Machines H02K 3/30 (20130101) Original (OR) Class H02K 3/50 (20130101) H02K 15/12 (20130101) H02K 15/105 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569826 | Tang et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Xiyuan Tang (Austin, Texas); Nan Sun (Austin, Texas) |
ABSTRACT | An exemplary incremental two-step capacitance-to-digital converter (CDC) with a time-domain sigma-delta modulator (TDΔΣM) includes a voltage-controlled oscillator (VCO)-based integrator that can be used in a low-order loop configuration. Example prototypes are disclosed, which when fabricated in 40-nm CMOS technology, provides CDC resolution of 0.29 fF while dissipating only 0.083 nJ per conversion. |
FILED | Tuesday, February 16, 2021 |
APPL NO | 17/176341 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/002 (20130101) Original (OR) Class H03M 3/458 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569863 | Tang et al. |
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FUNDED BY |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); VIRTUAL EM INC. (Ann Arbor, Michigan) |
INVENTOR(S) | Xinyao Tang (Cleveland Heights, Ohio); Soumyajit Mandal (Cleveland, Ohio); Joel B. Harley (Ann Arbor, Michigan); Tayfun Ozdemir (Ann Arbor, Michigan) |
ABSTRACT | In an example, a system includes a plurality of acoustically coupled nodes. Each of the nodes includes a transducer, a communication circuit and a controller. The transducer is adapted to be mechanically coupled to a medium. The communication circuit is coupled to the transducer to send and receive acoustic signals via the medium according to at least one communication parameter. The controller is to adaptively configure the at least one communication parameter of the communication circuit based on an acoustic signal received from at least one other of the nodes. |
FILED | Friday, September 25, 2020 |
APPL NO | 17/032693 |
ART UNIT | 2631 — Digital Communications |
CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 5/0066 (20130101) Transmission H04B 1/40 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569871 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
ASSIGNEE(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
INVENTOR(S) | Biao Chen (Jamesville, New York); Yang Liu (San Jose, California); Janek Mroczek (Barneveld, New York) |
ABSTRACT | A multiple-input multiple-output (MIMO) communication system that addresses three major challenges in airborne MIMO communications, namely, antenna blockage due largely to the movement and orientation of the airborne platforms, the presence of unknown interference inherent to the intended application, and the lack of channel state information (CSI) at the transmitter. The system is implemented on a Diagonal Bell-Labs Layered Space-Time (D-BLAST) MIMO architecture and includes spatial spreading to counter antenna blockage, temporal spreading to mitigate signal to interference and noise ratio degradation due to intended or unintended interference, and a simple low rate feedback scheme to enable real time adaptation in the absence of full transmitter CSI. |
FILED | Wednesday, November 10, 2021 |
APPL NO | 17/523538 |
ART UNIT | 2631 — Digital Communications |
CURRENT CPC | Transmission H04B 7/26 (20130101) H04B 7/0413 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0202 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11570392 | Tantawy |
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FUNDED BY |
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APPLICANT(S) | SENSEICS CORPORATION (Columbus, Ohio) |
ASSIGNEE(S) | Senseics Corporation (Columbus, Ohio) |
INVENTOR(S) | Ramy Tantawy (Columbus, Ohio) |
ABSTRACT | An imager device includes a pixel sensor configured to receive and convert incident radiation into a pixel signal and a readout circuit configured to receive the pixel signal from the pixel sensor, generate a received signal strength indicator (RSSI) value based on the pixel signal, and generate a digital signal based on the RSSI value and the pixel signal. |
FILED | Friday, May 29, 2020 |
APPL NO | 16/887983 |
ART UNIT | 2696 — Selective Visual Display Systems |
CURRENT CPC | Pictorial Communication, e.g Television H04N 5/378 (20130101) Original (OR) Class H04N 5/37455 (20130101) H04N 5/37457 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 11564409 | Lundberg |
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FUNDED BY |
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APPLICANT(S) | Brock M. Lundberg (Osseo, Wisconsin) |
ASSIGNEE(S) | |
INVENTOR(S) | Brock M. Lundberg (Osseo, Wisconsin) |
ABSTRACT | A composition of matter is used as an ingredient in consumable products (for humans and pets) comprising at least 0.005% by weight and preferably 1-30% by weight of highly refined cellulose fiber having at least 15% by total weight of the highly refined cellulose material of an oil-based flavoring or aroma-producing material, the composition of matter being provided as a free-flowing, dry-feel particulate material having a number average mean particle size of less than 2 mm. |
FILED | Friday, January 10, 2020 |
APPL NO | 16/739314 |
ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 27/12 (20160801) A23L 27/75 (20160801) Original (OR) Class A23L 33/24 (20160801) Shaping or Working of Foodstuffs, Not Fully Covered by a Single Other Subclass A23P 20/105 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564594 | Merrell et al. |
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FUNDED BY |
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APPLICANT(S) | Nano Composite Products, Inc. (Orem, Utah) |
ASSIGNEE(S) | Nano Composite Products, Inc. (Orem, Utah) |
INVENTOR(S) | Aaron Jake Merrell (Orem, Utah); Anton E. Bowden (Lindon, Utah); David T. Fullwood (Lindon, Utah); Matthew Kirk Seeley (Spanish Fork, Utah); Gavin Quinn Collins (Provo, Utah); Parker Gary Rosquist (Bluffdale, Utah); William Fredrick Christensen (Provo, Utah) |
ABSTRACT | In one example, an apparatus. includes a shoe having a sole with at least a portion of foam replaced with a composite polymeric foam, at least one probe disposed in the composite polymeric foam, a voltage detector coupled to the probe that detects voltage data generated by the composite polymeric foam, and a transformation module that converts voltage data generated by the composite polymeric foam in response to deformation events into GRF, acceleration, or pressure data. In another example, a method includes receiving voltage data produced by composite polymeric foam, the composite polymeric foam providing support and padding in the sole of a shoe, converting the voltage data to force data, comparing the force data to a profile, and transmitting, when the force data fails to fall within a threshold of the profile, a feedback signal to a physical feedback device, the feedback signal indicating a difference with the profile. |
FILED | Friday, September 06, 2019 |
APPL NO | 16/562808 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Characteristic Features of Footwear; Parts of Footwear A43B 3/34 (20220101) A43B 7/24 (20130101) Diagnosis; Surgery; Identification A61B 5/112 (20130101) A61B 5/486 (20130101) A61B 5/742 (20130101) A61B 5/1038 (20130101) Original (OR) Class A61B 5/6807 (20130101) A61B 5/7405 (20130101) A61B 2562/0261 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564598 | Kiourti et al. |
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FUNDED BY |
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APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
INVENTOR(S) | Asimina Kiourti (Columbus, Ohio); Vigyanshu Mishra (Columbus, Ohio) |
ABSTRACT | A system and method are provided for monitoring body kinematics. A wearable coil configuration of the system comprises at least first and second electrically-conductive coils adapted to be secured to a subject in a predetermined spatial relationship and orientation relative to one another. The first coil acts as a first transmitter and generates a first magnetic flux when a first electrical current is passed through it. The second coil acts as a receiver. The first magnetic flux induces a first electrical current or voltage in the second coil. A measurement instrument of the system is configured to measure the first electrical current or voltage and to output a first measurement signal. A processor, which may be part of, or external to, the system is configured to execute a motion monitoring algorithm that processes at least the measurement signal to determine at least a first motion made by the subject. |
FILED | Thursday, July 25, 2019 |
APPL NO | 16/522594 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1126 (20130101) Original (OR) Class A61B 5/4528 (20130101) A61B 5/6804 (20130101) A61B 2503/40 (20130101) A61B 2562/0223 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564701 | Pak et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Nikita Pak (Allston, Massachusetts); Justin P. Kinney (Quincy, Massachusetts); Edward S. Boyden (Chestnut Hill, Massachusetts) |
ABSTRACT | An automated craniotomy opening apparatus includes a drilling apparatus with a drilling tip, at least one drilling apparatus positioning device, a detection device, and a computer processor that automatically controls the drilling apparatus, the positioning device, and the detection device. A method for automated opening of craniotomies includes, under automatic control of a computer processor, drilling into a skull for a predetermined distance and determining when there is a conductance drop near the drilling tip that indicates skull breakthrough. If the conductance is not below a predetermined threshold, drilling continues iteratively manner until conductance is below the threshold. A craniotomy pattern may be predetermined and automatically drilled under control of the processor. A cranial window may be created by drilling along a path that interpolates between holes to form the circumference of the window. Determining conductance may include use of an impedance detection circuit. |
FILED | Tuesday, November 03, 2020 |
APPL NO | 17/088494 |
ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1695 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 34/32 (20160201) A61B 90/10 (20160201) A61B 2017/00026 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564854 | Cooper et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Aftairs (Washington, District of Columbia) |
INVENTOR(S) | Rory Alan Cooper (Gibsonia, Pennsylvania); Chengshiu Chung (Pittsburgh, Pennsylvania); Garrett G. Grindle (Pittsburgh, Pennsylvania); Rosemarie Cooper (Gibsonia, Pennsylvania); Sathish Andrea Sundaram (Pittsburgh, Pennsylvania) |
ABSTRACT | A wheelchair system includes a wheelchair including a plurality of force sensors including at least three force sensors. A rigid seat pan is placed in contact with each the plurality of force sensors at a different position on the rigid seat pan so that the rigid seat pan does not contact the frame and forces on the rigid seat pan are transferred to the plurality of force sensors. Each of the plurality of force sensors is in communicative connection with a processor system. A memory system is in communicative connection and an interface system is in connection with the processor system and a user interface system in communicative connection with the processor system. Instructions stored on the memory system are executable by the processor system to determine a value of a variable related to a distribution of force on the rigid seat pan over time. |
FILED | Thursday, July 11, 2019 |
APPL NO | 17/259173 |
ART UNIT | 3618 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/128 (20161101) A61G 5/1043 (20130101) A61G 5/1091 (20161101) Original (OR) Class A61G 2203/32 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/30 (20180101) G16H 40/63 (20180101) G16H 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11564884 | Reineke et al. |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Theresa Reineke (Vadnais Heights, Minnesota); Zhe Tan (Secaucus, New Jersey); Yaming Jiang (Marlborough, Massachusetts); Mitra S Ganewatta (Ladson, South Carolina); Timothy P. Lodge (Minneapolis, Minnesota) |
ABSTRACT | A compound includes an amphiphilic polymer with a hydrophobic block including monomeric units chosen from alkyl (meth)acrylates, alkyl (meth)acrylamides, and combinations thereof; and a hydrophilic cationic block including monomeric units chosen from alkylamino (meth)acrylates, alkylamino (meth)acrylamides, and combinations thereof. The polymer is in the form of a micelle with a central core derived from the hydrophobic block and shell at least partially surrounding the core. The shell includes a plurality of filamentous arms derived from the hydrophilic block and emanating outward from the core. A biological agent is associated with the arms of the micelle. |
FILED | Wednesday, September 09, 2020 |
APPL NO | 17/015968 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/1075 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 47/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565027 | Schmidt et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, the University of Texas System (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Christine E. Schmidt (Gainesville, Florida); Scott A. Zawko (Austin, Texas); Sarah M. Mayes (Austin, Texas) |
ABSTRACT | A biocompatible membrane comprised of alginate and hyaluronate. The membrane may be used to prevent unwanted scarring after surgery. The tissue adherence and the rate of bioresorption of the membrane may be modified through an external stimulus comprising a sequestering agent and a viscosity modifier. |
FILED | Thursday, November 19, 2020 |
APPL NO | 16/952155 |
ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0077 (20130101) A61F 2002/009 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/16 (20130101) A61L 31/041 (20130101) A61L 31/041 (20130101) A61L 31/041 (20130101) A61L 31/041 (20130101) A61L 31/145 (20130101) Original (OR) Class A61L 31/148 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 5/18 (20130101) C08J 2305/04 (20130101) C08J 2405/08 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/08 (20130101) C08L 89/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565124 | Mohseni |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Hooman Mohseni (Wilmette, Illinois) |
ABSTRACT | A neural sensing system includes an interrogator that includes an optical head. The optical head is configured to transmit a light signal. The neural sensing system also includes a microprobe configured to contact tissue. The microprobe includes a transducer configured to receive the light signal and modulate the light signal with neural signal information sensed from the tissue. The microprobe also includes a retroreflector configured to reflect the modulated light signal back to the optical head of the interrogator. |
FILED | Wednesday, August 15, 2018 |
APPL NO | 16/638218 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0601 (20130101) A61N 5/0622 (20130101) Original (OR) Class A61N 2005/063 (20130101) A61N 2005/0628 (20130101) A61N 2005/0665 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565247 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Honda Motor Co., Ltd. (Tokyo, Japan); The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | HONDA MOTOR CO., LTD. (Tokyo, Japan); THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Xufan Li (Fremont, California); Avetik Harutyunyan (Santa Clara, California); Xiangye Liu (Xi'an, China PRC); Baiching Li (New York, New York); James Curtis Hone (New York, New York); Daniel V. Esposito (New York, New York) |
ABSTRACT | Aspects of the present disclosure generally relate to catalyst compositions including metal chalcogenides, processes for producing such catalyst compositions, processes for enhancing catalytic active sites in such catalyst compositions, and uses of such catalyst compositions in, e.g., processes for producing conversion products. In an aspect, a process for forming a catalyst composition is provided. The process includes introducing an electrolyte material and an amphiphile material to a metal chalcogenide to form the catalyst composition. In another aspect, a catalyst composition is provided. The catalyst composition includes a metal chalcogenide, an electrolyte material, and an amphiphile material. Devices for hydrogen evolution reaction are also provided. |
FILED | Thursday, March 11, 2021 |
APPL NO | 17/199129 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/043 (20130101) B01J 27/051 (20130101) B01J 27/0573 (20130101) B01J 27/0576 (20130101) B01J 37/344 (20130101) Original (OR) Class Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/075 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565979 | Temme et al. |
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FUNDED BY |
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APPLICANT(S) | Pivot Bio, Inc. (Berkeley, California) |
ASSIGNEE(S) | Pivot Bio, Inc. (Berkeley, California) |
INVENTOR(S) | Karsten Temme (Oakland, California); Alvin Tamsir (San Francisco, California); Sarah Bloch (Emeryville, California); Rosemary Clark (El Cerrito, California); Emily Tung (Milbrae, California); Kevin Hammill (Danville, California); Douglas Higgins (Berkeley, California); Austin Davis-Richardson (San Francisco, California) |
ABSTRACT | Methods and systems are provided for generating and utilizing a bacterial composition that comprises at least one genetically engineered bacterial strain that fixes atmospheric nitrogen in an agricultural system that has been fertilized with more than 20 lbs of Nitrogen per acre. |
FILED | Thursday, November 15, 2018 |
APPL NO | 16/192738 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 3/00 (20130101) A01H 6/4684 (20180501) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/20 (20200101) A01N 63/20 (20200101) A01N 63/20 (20200101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/04 (20130101) C12N 1/20 (20130101) C12N 1/205 (20210501) C12N 15/52 (20130101) C12N 15/70 (20130101) C12N 15/111 (20130101) C12N 15/743 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/01 (20210501) C12R 2001/07 (20210501) C12R 2001/22 (20210501) C12R 2001/025 (20210501) C12R 2001/065 (20210501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566173 | Arachchige et al. |
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APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
ASSIGNEE(S) | Virginia Commonwealth University (Richmond, Virginia) |
INVENTOR(S) | Indika U. Arachchige (Henrico, Virginia); Umit Ozgur (Richmond, Virginia); Denis O. Demchenko (Richmond, Virginia); Venkatesham Tallapally (Richmond, Virginia); Tanner A. Nakagawara (Richmond, Virginia) |
ABSTRACT | Colloidal synthesis of narrowly disperse, near IR emitting Group IV alloy quantum dots with wide range of Sn compositions via reduction of precursor halides is provided, allowing for less-toxic, earth abundant, and silicon-compatible Group IV alloy quantum dots for application in a broad range of electronic and photonic technologies. |
FILED | Monday, March 18, 2019 |
APPL NO | 16/981452 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/66 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/426 (20130101) H01L 51/442 (20130101) H01L 51/447 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566238 | Sonnenburg et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Novome Biotechnologies, Inc. (Daly City, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Novome Biotechnologies, Inc. (Daly City, California) |
INVENTOR(S) | Justin L. Sonnenburg (Redwood City, California); Weston R. Whitaker (Daly City, California); Elizabeth Stanley (Portola Valley, California); William C. DeLoache (Oakland, California) |
ABSTRACT | Compositions and methods are provided for modulating growth of a genetically modified bacterial cell present in a human organ, for modulating growth of a genetically modified bacterial cell in an organ (e.g., gut), for displacing at least a portion of a population of bacterial cells in an organ, and for facilitating gut colonization by a genetically modified bacterial cell. Also provided are genetically modified bacterial cells, e.g., cells that include a heterologous carbohydrate-utilization gene or gene set that provides for the ability to utilize as a carbon source a rare carbohydrate of interest that is utilized as a carbon source by less than 50% of bacterial cells present in a human microbiome. |
FILED | Thursday, December 14, 2017 |
APPL NO | 16/468542 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/741 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/2402 (20130101) Original (OR) Class C12N 15/52 (20130101) C12N 15/74 (20130101) Enzymes C12Y 302/01178 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566328 | Amador et al. |
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APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
INVENTOR(S) | Jennie M. Amador (Corvallis, Oregon); Douglas A. Keszler (Corvallis, Oregon); James Sommers (Corvallis, Oregon) |
ABSTRACT | Aqueous solutions of halogenides (oxyhalides) of zirconium and hafnium (M) with values of α=X/M near one, for X=Cl, Br and I form amorphous solids or glasses, designated as M,X, in contrast to important crystalline oxyhalide end members with α=2 (designated as MOX). The present disclosure describes methods for producing amorphous thin films comprising halogenides upon evaporation, and provides some measured physical properties, with attention to compositions for α<2. The value of a below which only glasses are formed is about one for oxychlorides and oxybromides of both Zr and Hf. The chemical formulas for all the halogenide thin films prepared as noted above can be written as a function of the single parameter α, according to M(OH)4-αXα.(4α-1)H2O. This is valid for e.g., crystalline zirconium oxychloride octahydrate, and for the glassy solids found for α<2 and down to the onset of hydrolysis, α≈0.5. Thin films made by the disclosed methods are highly dense (90% of theoretical crystal density), extremely smooth (rms<0.4 nm), and highly transparent in the visible spectrum, >90%. Such thin films are useful as alkali diffusion barriers. |
FILED | Wednesday, June 17, 2020 |
APPL NO | 16/904365 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/1208 (20130101) Original (OR) Class C23C 18/1241 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566993 | Javidi et al. |
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FUNDED BY |
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APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
INVENTOR(S) | Bahram Javidi (Storrs, Connecticut); Adam Markman (Orange, Connecticut); Siddharth Rawat (Storrs, Connecticut); Arun Anand (Gujarat, India) |
ABSTRACT | The present disclosure provides improved systems and methods for automated cell identification/classification. More particularly, the present disclosure provides advantageous systems and methods for automated cell identification/classification using shearing interferometry with a digital holographic microscope. The present disclosure provides for a compact, low-cost, and field-portable 3D printed system for automatic cell identification/classification using a common path shearing interferometry with digital holographic microscopy. This system has demonstrated good results for sickle cell disease identification with human blood cells. The present disclosure provides that a robust, low cost cell identification/classification system based on shearing interferometry can be used for accurate cell identification. For example, by combining both the static features of the cell along with information on the cell motility, classification can be performed to determine the type of cell present in addition to the state of the cell (e.g., diseased vs. healthy). |
FILED | Monday, February 11, 2019 |
APPL NO | 16/272781 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) Original (OR) Class G01N 15/1468 (20130101) G01N 2015/1006 (20130101) G01N 2015/1075 (20130101) G01N 2015/1087 (20130101) G01N 2015/1093 (20130101) G01N 2015/1486 (20130101) Optical Elements, Systems, or Apparatus G02B 21/14 (20130101) Holographic Processes or Apparatus G03H 1/0443 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/62 (20170101) G06T 2207/10016 (20130101) G06T 2207/10056 (20130101) G06T 2207/10152 (20130101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) Image or Video Recognition or Understanding G06V 20/698 (20220101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566994 | Kung et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Yu-Chun Kung (South Pasadena, California); Tianxing Man (Los Angeles, California); Pei-Yu E. Chiou (Los Angeles, California) |
ABSTRACT | In certain embodiments a device is provided for electrorotation flow. In certain embodiments the device comprises a microfluidic channel comprising a plurality of electrodes disposed to provide dielectrophoretic (DEP) forces that are perpendicular to hydrodynamic flows along the channel; and a fluid within the channel providing the hydrodynamic flow along the channel; wherein the device is configured to apply focusing voltages to the electrodes that provide an electric field minimum in the channel and that focus cells, particles, and/or molecules or molecular complexes within the channel; and where the device is configured to apply rotation-inducing voltages to the electrodes that induce rotation of the cells, particles, molecules and/or molecular complexes as they flow through the channel. |
FILED | Thursday, April 05, 2018 |
APPL NO | 16/500382 |
ART UNIT | 2481 — Recording and Compression |
CURRENT CPC | Peptides C07K 1/026 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) G01N 15/1425 (20130101) Original (OR) Class G01N 15/1459 (20130101) G01N 15/1463 (20130101) G01N 15/1475 (20130101) G01N 27/00 (20130101) G01N 2015/1006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567015 | Klein |
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FUNDED BY |
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APPLICANT(S) | Boulder Environmental Sciences and Technology (Boulder, Colorado) |
ASSIGNEE(S) | Boulder Environmental Sciences and Technology (Boulder, Colorado) |
INVENTOR(S) | Marian Klein (Boulder, Colorado) |
ABSTRACT | A system for passive microwave remote sensing using at least one microwave radiometer includes a fixed body portion and a mobile body portion. The mobile body portion is configured for rotatably coupling with the fixed body portion for rotation about a rotation axis. The mobile body portion is configured for supporting the microwave radiometer therein such that the microwave radiometer rotates about the rotation axis when the mobile body portion is rotated about the rotation axis such that a polarization axis of the radiometer is aligned with an earth axis. The fixed body portion includes a motor mechanism for effecting rotation of the mobile body portion. In an embodiment, the mobile body portion includes a plurality of body section, each body section being configured for supporting a microwave radiometer therein. In another embodiment, each one of the plurality of body sections is configured to be interchangeably coupled with each other. |
FILED | Wednesday, December 30, 2020 |
APPL NO | 17/138268 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) G01N 22/04 (20130101) Original (OR) Class G01N 33/2823 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 25/04 (20130101) G01R 27/04 (20130101) G01R 27/22 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/17 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567039 | Joshi et al. |
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FUNDED BY |
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APPLICANT(S) | Marquette University (Milwaukee, Wisconsin) |
ASSIGNEE(S) | Marquette University (Milwaukee, Wisconsin) |
INVENTOR(S) | Shrinivas G. Joshi (Brookfield, Wisconsin); Meghna Saikia (Milwaukee, Wisconsin) |
ABSTRACT | Passive wireless sensors include an antenna. The antenna receives a combined signal. The combined signal includes a low frequency modulating signal modulated on a high frequency carrier wave. A demodulator receives the combined signal and extracts the modulating signal. A sensor receives the extracted modulating signal and produces an output signal with a time delay indicative of a property to be sensed. A modulator receives the output signal and the high frequency carrier wave and modulates the output signal onto the high frequency carrier wave to create a combined output signal broadcast by the antenna. |
FILED | Monday, December 07, 2020 |
APPL NO | 17/113462 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/66 (20130101) G01F 1/662 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/44 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567084 | Ray et al. |
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FUNDED BY |
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APPLICANT(S) | Research Foundation for State University of New York (Buffalo, New York) |
ASSIGNEE(S) | The Research Foundation for the State University of New York (Amherst, New York) |
INVENTOR(S) | Steven J. Ray (Williamsville, New York); Maria Elisa Rivera-Albarran (Amherst, New York) |
ABSTRACT | A microwave microstrip resonator apparatus including a housing; a resonator within the housing; an output conductor within the housing and spaced apart from the resonator so as to define a capacitive gap therebetween; a reaction vessel configured to reside with the capacitive gap; and a power supply coupled to the resonator whereby contents within the reaction vessel are heated when energy is supplied to the resonator by the power supply. A mass spectrometer may also be coupled to an outlet end of the reaction vessel such that the contents within the reaction vessel are, simultaneously, delivered to the mass spectrometer for analysis. |
FILED | Monday, May 11, 2020 |
APPL NO | 16/871678 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/126 (20130101) B01J 2219/1206 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 30/7266 (20130101) G01N 33/6848 (20130101) Original (OR) Class G01N 2030/027 (20130101) G01N 2570/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/36 (20130101) H01J 49/165 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567207 | Che et al. |
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APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
INVENTOR(S) | Erzhuo Che (Corvallis, Oregon); Michael Olsen (Corvallis, Oregon) |
ABSTRACT | A computer implemented scheme for a light detection and ranging (LIDAR) system where point cloud feature extraction and segmentation by efficiently is achieved by: (1) data structuring; (2) edge detection; and (3) region growing. |
FILED | Thursday, July 30, 2020 |
APPL NO | 16/943991 |
ART UNIT | 2488 — Recording and Compression |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4804 (20130101) G01S 17/89 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/13 (20170101) G06T 7/136 (20170101) G06T 7/174 (20170101) G06T 7/187 (20170101) G06T 2207/10028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11568044 | Butler et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
INVENTOR(S) | Kevin Butler (Gainesville, Florida); Tuba Yavuz (Gainesville, Florida); Jing Tian (Gainesville, Florida); Grant Hernandez (Gainesville, Florida); Farhaan Fowze (Gainesville, Florida) |
ABSTRACT | Example embodiments provide methods, apparatuses, systems, computing devices, and/or the like for vetting USB device firmware via a USB-specific firmware analysis framework. In one example, a method is provided for analyzing firmware of a Universal Serial Bus (USB) device. The example method includes steps of receiving a firmware image extracted from the USB device, identifying signatures from the firmware image relating to USB operation, and building an expected model of operation of the USB device using the identified signatures and a database of operational information regarding USB devices. The example method further includes the steps of generating a recovered model of operation of the USB device based on the firmware image and the identified signatures, and comparing the recovered model of operation with the expected model of operation to identify unexpected or unknown behaviors. The example method may further include generating a report comprising the identified unexpected or unknown behaviors. |
FILED | Tuesday, March 19, 2019 |
APPL NO | 16/358385 |
ART UNIT | 2491 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 13/4282 (20130101) G06F 21/57 (20130101) G06F 21/552 (20130101) Original (OR) Class G06F 2213/0042 (20130101) G06F 2221/033 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11568161 | Langerman et al. |
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APPLICANT(S) | South Dakota Board of Regents (Pierre, South Dakota) |
ASSIGNEE(S) | SOUTH DAKOTA BOARD OF REGENTS (Pierre, South Dakota) |
INVENTOR(S) | David Langerman (Rapid City, South Dakota); Jon Kellar (Rapid City, South Dakota); William Cross (Rapid City, South Dakota); P. Stanley May (Rapid City, South Dakota); Julian Brackins (Rapid City, South Dakota); Jeevan Meruga (Rapid City, South Dakota); Aravind Baride (Rapid City, South Dakota); John Rapp (Rapid City, South Dakota) |
ABSTRACT | An improved system and method for reading an upconversion response from nanoparticle inks is provided. A is adapted to direct a near-infrared excitation wavelength at a readable indicia, resulting in a near-infrared emission wavelength created by the upconverting nanoparticle inks. A short pass filter may filter the near-infrared excitation wavelength. A camera is in operable communication with the short pass filter and receives the near-infrared emission wavelength of the readable indicia. The system may further include an integrated circuit adapted to receive the near-infrared emission wavelength from the camera and generate a corresponding signal. A readable application may be in operable communication with the integrated circuit. The readable application receives the corresponding signal, manipulates the signal, decodes the signal into an output, and displays and/or stores the output. |
FILED | Wednesday, May 27, 2020 |
APPL NO | 16/884474 |
ART UNIT | 2887 — Optics |
CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/29 (20141001) B42D 25/382 (20141001) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/03 (20130101) C09D 11/037 (20130101) C09D 11/50 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7766 (20130101) C09K 11/7783 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) G01N 21/6456 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1417 (20130101) G06K 7/10564 (20130101) Original (OR) Class Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/00 (20130101) G07D 7/005 (20170501) G07D 7/0043 (20170501) G07D 7/1205 (20170501) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/57 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569403 | Yang et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
INVENTOR(S) | Rui Q. Yang (Norman, Oklahoma); Wenxiang Huang (Norman, Oklahoma) |
ABSTRACT | A PV device comprises a first mirror comprising a reflectance of higher than 50%; a second mirror interface; and an optical cavity positioned between the first mirror and the second mirror interface and comprising at least one IC stage. Each of the at least one IC stage comprises a conduction band; a valence band; a hole barrier comprising a first band gap; an absorption region coupled to the hole barrier, comprising a second band gap that is less than the first band gap, and configured to absorb photons; and an electron barrier coupled to the absorption region so that the absorption region is positioned between the hole barrier and the electron barrier. The electron barrier comprises a third band gap that is greater than the second band gap. The PV device is configured to operate at a forward bias voltage with a net photon absorption for generating an electric output. |
FILED | Thursday, June 10, 2021 |
APPL NO | 17/344613 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/0816 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0547 (20141201) Original (OR) Class H01L 31/0735 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569826 | Tang et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Xiyuan Tang (Austin, Texas); Nan Sun (Austin, Texas) |
ABSTRACT | An exemplary incremental two-step capacitance-to-digital converter (CDC) with a time-domain sigma-delta modulator (TDΔΣM) includes a voltage-controlled oscillator (VCO)-based integrator that can be used in a low-order loop configuration. Example prototypes are disclosed, which when fabricated in 40-nm CMOS technology, provides CDC resolution of 0.29 fF while dissipating only 0.083 nJ per conversion. |
FILED | Tuesday, February 16, 2021 |
APPL NO | 17/176341 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/002 (20130101) Original (OR) Class H03M 3/458 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569871 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
ASSIGNEE(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
INVENTOR(S) | Biao Chen (Jamesville, New York); Yang Liu (San Jose, California); Janek Mroczek (Barneveld, New York) |
ABSTRACT | A multiple-input multiple-output (MIMO) communication system that addresses three major challenges in airborne MIMO communications, namely, antenna blockage due largely to the movement and orientation of the airborne platforms, the presence of unknown interference inherent to the intended application, and the lack of channel state information (CSI) at the transmitter. The system is implemented on a Diagonal Bell-Labs Layered Space-Time (D-BLAST) MIMO architecture and includes spatial spreading to counter antenna blockage, temporal spreading to mitigate signal to interference and noise ratio degradation due to intended or unintended interference, and a simple low rate feedback scheme to enable real time adaptation in the absence of full transmitter CSI. |
FILED | Wednesday, November 10, 2021 |
APPL NO | 17/523538 |
ART UNIT | 2631 — Digital Communications |
CURRENT CPC | Transmission H04B 7/26 (20130101) H04B 7/0413 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0202 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569897 | Paramesh et al. |
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FUNDED BY |
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APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Jeyanandh Paramesh (Pittsburgh, Pennsylvania); Susnata Mondal (Pittsburgh, Pennsylvania); L. Richard Carley (Pittsburgh, Pennsylvania) |
ABSTRACT | Disclosed herein is an innovative multi-layer hybrid/digital MIMO architecture that comprises single-stream or fully-connected (FC) multi-stream beamforming tiles (with RF complex-weights) in the first layer, followed by a fully connected (analog/digital) baseband layer. This architecture overcomes the complexity versus spectral-efficiency tradeoffs of existing hybrid MIMO architectures and enables MIMO stream/user scalability, superior energy-efficiency, and spatial-processing flexibility. |
FILED | Monday, February 01, 2021 |
APPL NO | 17/164079 |
ART UNIT | 2632 — Digital Communications |
CURRENT CPC | Transmission H04B 1/16 (20130101) H04B 1/0028 (20130101) H04B 1/0078 (20130101) H04B 7/088 (20130101) Original (OR) Class H04B 7/0413 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11570420 | Redden |
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FUNDED BY |
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APPLICANT(S) | Blue River Technology Inc. (Sunnyvale, California) |
ASSIGNEE(S) | Blue River Technology Inc. (Sunnyvale, California) |
INVENTOR(S) | Lee Kamp Redden (Palo Alto, California) |
ABSTRACT | Described are methods for identifying the in-field positions of plant features on a plant by plant basis. These positions are determined based on images captured as a vehicle (e.g., tractor, sprayer, etc.) including one or more cameras travels through the field along a row of crops. The in-field positions of the plant features are useful for a variety of purposes including, for example, generating three-dimensional data models of plants growing in the field, assessing plant growth and phenotypic features, determining what kinds of treatments to apply including both where to apply the treatments and how much, determining whether to remove weeds or other undesirable plants, and so on. |
FILED | Thursday, June 30, 2022 |
APPL NO | 17/853925 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6277 (20130101) Image Data Processing or Generation, in General G06T 7/593 (20170101) G06T 2207/10021 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30252 (20130101) Image or Video Recognition or Understanding G06V 20/38 (20220101) G06V 2201/12 (20220101) Pictorial Communication, e.g Television H04N 13/128 (20180501) H04N 13/204 (20180501) Original (OR) Class H04N 13/239 (20180501) H04N 13/243 (20180501) H04N 13/271 (20180501) H04N 2013/0081 (20130101) H04N 2013/0092 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11570922 | Choi et al. |
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FUNDED BY |
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APPLICANT(S) | SEOUL NATIONAL UNIVERSITY R and DB FOUNDATION (Seoul, South Korea); George Mason Research Foundation, Inc. (Fairfax, Virginia) |
ASSIGNEE(S) | Seoul National University R and DB Foundation (Seoul, South Korea); George Mason Research Foundation, Inc. (Fairfax, Virginia) |
INVENTOR(S) | In Suk Choi (Seoul, South Korea); Yu Ki Lee (Seoul, South Korea); Young Joo Lee (Seoul, South Korea); Jyh-Ming Lien (Oakton, Virginia) |
ABSTRACT | Provided is a method of manufacturing an electronic apparatus, the method including approximating a surface of a three-dimensional (3D) structure with two-dimensional (2D) meshes, forming a developed view by developing the 2D meshes, manufacturing an electronic apparatus having the same shape as a shape of the developed view, and attaching the electronic apparatus to the surface of the 3D structure. |
FILED | Friday, May 10, 2019 |
APPL NO | 17/054742 |
ART UNIT | 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Image Data Processing or Generation, in General G06T 17/20 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/04 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 11564919 | Harmon et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Brooke Nicole Harmon (Livermore, California); Oscar Negrete (Livermore, California); Joseph S. Schoeniger (Oakland, California); Edwin A. Saada (Dublin, California) |
ABSTRACT | An in vitro assay was designed to measure the activity of the alphavirus non-structural protein 2 (nsP2), which is the viral protease and is required for viral replication. By taking advantage of fluorescence-resonance energy transfer between two proteins, a protease cleavage assay was generated. This was utilized for high-throughput screening of 40,000 small molecules. Inhibitors were validated using cell-based assays to measure alphavirus infection and cytotoxicity. Certain compounds were then characterized for anti-viral efficacy in various cell lines in numerous assays. Compounds were tested against Chikungunya virus, Venezuelan Equine Encephalitis virus, Rift Valley Fever virus, and Zika virus. Three compounds (compounds I, II, and III) showed pan-alphavirus anti-viral efficacy at concentrations that did not result in cell toxicity. An additional compound, structure IV, showed broad spectrum inhibition of all viruses tested. Pharmaceutical preparations and methods of treatment including these compounds are provided herein. |
FILED | Tuesday, March 02, 2021 |
APPL NO | 17/189596 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0029 (20130101) A61K 9/0053 (20130101) A61K 31/53 (20130101) A61K 31/426 (20130101) A61K 31/428 (20130101) A61K 31/496 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565256 | Reiserer et al. |
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FUNDED BY |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
INVENTOR(S) | Ronald S. Reiserer (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); Philip C. Samson (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Michael Geuy (Nashville, Tennessee); Lisa J. McCawley (Nashville, Tennessee); John P. Wikswo (Brentwood, Tennessee) |
ABSTRACT | Microfluidic systems, pumps, valves and applications of the same are provided. The microfluidic system may be a pump or a valve having a fluidic chip and an actuator controlling the opening and closing of the fluidic channel in the fluidic chip. The actuator may be disposed to tilt from the fluidic chip, forming a tilted-rotor peristaltic pump. Alternatively, the actuator may be a rolling ball actuator, and different fluidic chips may be used in different applications. For example, the fluidic chip may be a spiral pump chip having spiral channels, a rotary peristaltic pump chip having multiple output channels, or a multi-port valve chip having one port interconnected with multiple different ports. An analytical valve chip may switchably interconnect bioreactor and rinse/calibration input channels to sensor and waste output channels. The actuator of a random-access valve can move from one valve position to another without opening or closing intermediate ones. |
FILED | Monday, June 29, 2020 |
APPL NO | 17/623350 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) Original (OR) Class B01L 2300/123 (20130101) B01L 2300/0627 (20130101) B01L 2400/0644 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/1261 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/163 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565318 | Rios et al. |
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FUNDED BY |
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APPLICANT(S) | Orlando Rios (Knoxville, Tennessee); Craig A. Bridges (Knoxville, Tennessee); Amelia M. Elliott (Knoxville, Tennessee); Hunter B. Henderson (Livermore, California); Michael S. Kesler (Knoxville, Tennessee); Zachary Sims (Knoxville, Tennessee); David Weiss (Manitowoc, Wisconsin) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee); Eck Industries Incorporated (Manitowoc, Wisconsin) |
INVENTOR(S) | Orlando Rios (Knoxville, Tennessee); Craig A. Bridges (Knoxville, Tennessee); Amelia M. Elliott (Knoxville, Tennessee); Hunter B. Henderson (Livermore, California); Michael S. Kesler (Knoxville, Tennessee); Zachary Sims (Knoxville, Tennessee); David Weiss (Manitowoc, Wisconsin) |
ABSTRACT | A reactive matrix infiltration process is described herein, which includes contacting a surface of a preform comprising reinforcement material particles with a molten infiltrant comprising a matrix material, the matrix material comprising an Al—Ce alloy, whereby the infiltrant at least partially fills spaces between the reinforcement material particles by capillary action and reacts with the reinforcement material particles to form a composite material form, the composite material comprising the matrix material, at least one intermetallic phase, and, optionally, reinforcement material particles. A composite material form also is described, which includes a plurality of reinforcement material particles comprising a metal alloy or a ceramic, a matrix material at least partially filling spaces between the reinforcement material particles; and at least one intermetallic phase surrounding at least some of the reinforcement material particles. The reinforcement material particles and intermetallic phase together may form a gradient core-shell structure. |
FILED | Thursday, September 03, 2020 |
APPL NO | 17/011316 |
ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/26 (20130101) B22F 7/08 (20130101) Original (OR) Class B22F 2301/205 (20130101) Alloys C22C 14/00 (20130101) C22C 21/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565722 | Oh et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
INVENTOR(S) | Geunseob Oh (Ann Arbor, Michigan); Huei Peng (Ann Arbor, Michigan) |
ABSTRACT | A system and method for determining a predicted trajectory of a human-driven host vehicle as the human-driven host vehicle approaches a traffic signal. The method includes: obtaining a host vehicle-traffic light distance dx and a longitudinal host vehicle speed vx that are each taken when the human-driven host vehicle approaches the traffic signal; obtaining a traffic light signal phase Pt and an traffic light signal timing Tt; obtaining a time of day TOD; providing the host vehicle-traffic light distance dx, the longitudinal host vehicle speed vx, the traffic light signal phase Pt, the traffic light signal timing Tt, and the time of day TOD as input into an artificial intelligence (AI) vehicle trajectory prediction application, wherein the AI vehicle trajectory prediction application implements an AI vehicle trajectory prediction model; and determining the predicted trajectory of the human-driven host vehicle using the AI vehicle trajectory prediction application. |
FILED | Friday, January 15, 2021 |
APPL NO | 17/150690 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 40/04 (20130101) B60W 60/0027 (20200201) Original (OR) Class B60W 2554/80 (20200201) B60W 2554/4042 (20200201) B60W 2554/4045 (20200201) B60W 2556/65 (20200201) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Wireless Communication Networks H04W 4/44 (20180201) H04W 4/46 (20180201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565779 | Lynn et al. |
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FUNDED BY |
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APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
ASSIGNEE(S) | Other Lab, LLC (San Francisco, California) |
INVENTOR(S) | Peter Sturt Lynn (Alameda, California); Jonathan B. Pompa (Long Beach, California) |
ABSTRACT | A method of installing one or more anchors in an underwater substrate in a body of water including installing an anchor into the underwater substrate by rotating an anchor installation vehicle about a central axis Y to drive the anchor coupled to the anchor installation vehicle into the underwater substrate. The anchor installation vehicle includes a vehicle frame having a top end and bottom end, a plurality of arms extending outward from the vehicle frame, one or more rotational thrusters disposed at distal ends of the respective arms, and an anchor system that holds the anchor extending from the bottom end of the vehicle frame with the anchor aligned with a central axis Y. |
FILED | Wednesday, January 27, 2021 |
APPL NO | 17/159632 |
ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 21/20 (20130101) B63B 21/26 (20130101) B63B 79/10 (20200101) B63B 79/40 (20200101) Original (OR) Class Marine Propulsion or Steering B63H 11/00 (20130101) Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 5/801 (20130101) E02D 7/22 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565983 | Sutton et al. |
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FUNDED BY |
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APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Andrew D. Sutton (Oak Ridge, Tennessee); Cameron M. Moore (White Rock, New Mexico); Orion Staples (Philadelphia, Pennsylvania); Troy A. Semelsberger (Los Alamos, New Mexico); William L. Kubic, Jr. (White Rock, New Mexico) |
ABSTRACT | Embodiments of a system and method are disclosed for obtaining high-energy fuels. In some embodiments, the system and method produces one or more fused cyclic compounds that can include one or more bridging points. The fused cyclic compounds are suitable for use as a high-energy fuels, and may be derived from biomass. |
FILED | Friday, August 27, 2021 |
APPL NO | 17/446224 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 3/143 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0013 (20130101) B01J 19/245 (20130101) B01J 21/04 (20130101) B01J 21/12 (20130101) B01J 23/72 (20130101) B01J 23/755 (20130101) B01J 2219/00033 (20130101) B01J 2219/00157 (20130101) Acyclic or Carbocyclic Compounds C07C 1/24 (20130101) Original (OR) Class C07C 2/08 (20130101) C07C 29/103 (20130101) C07C 45/59 (20130101) C07C 2601/08 (20170501) C07C 2601/10 (20170501) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565989 | Moore et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Department of Energy (Washington, District of Columbia) |
ASSIGNEE(S) | |
INVENTOR(S) | Cameron Moore (Los Alamos, New Mexico); Trideep Rajale (Los Alamos, New Mexico); Karthikeyan K. Ramasamy (Richland, Washington); Andrew Sutton (Los Alamos, New Mexico) |
ABSTRACT | The invention relates to a two-way approach to isolate, recover and upgrade 2,3-Butanediol (2,3-BDO) from fermentation broth. A complete separation and recovery process for 2,3-BDO using acetalization and trans-acetalization sequence. Acetalization with butyraldehyde using heterogeneous catalysts, either Amberlyst-15® or Nafion NR50®, efficiently isolates 2,3-BDO as phase-separated protected dioxolane. The approach provides significant process advantages with easy product recovery and high recyclability of the catalyst. Trans-acetalization of dioxolane with methanol (methanolysis) followed by distillation of acetal, yielded very high purity 2,3-BDO with about 90% isolated yield. Alternatively, dioxolane is used in a process direct to methyl ethyl ketone (MEK) as a BDO synthon allowing for recovery of the aldehyde. |
FILED | Tuesday, November 03, 2020 |
APPL NO | 17/087841 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 29/92 (20130101) Original (OR) Class C07C 29/92 (20130101) C07C 31/207 (20130101) C07C 31/207 (20130101) C07C 2521/12 (20130101) C07C 2531/025 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566009 | Chavez et al. |
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FUNDED BY |
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APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico); The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico); The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | David Chavez (Los Alamos, New Mexico); Jesse Sabatini (Bel Air, Maryland); Pablo Guzmán (Bel Air, Maryland); Leah Wingard (Landenberg, Pennsylvania); Eric Johnson (Millington, Maryland) |
ABSTRACT | Disclosed herein are embodiments of an energetic compound and methods of making and using the same. Energetic compound embodiments disclosed herein exhibit physical and chemical properties that facilitate their use in various applications, such as high energy propellant plasticizers, melt-castable explosives, and the like. Efficient and safe method embodiments for making the disclosed energetic compound embodiments are described herein. |
FILED | Friday, May 15, 2020 |
APPL NO | 16/875544 |
ART UNIT | 1699 — Organic Chemistry |
CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 25/34 (20130101) Heterocyclic Compounds C07D 271/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566088 | Redline et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Erica Marie Redline (Albuquerque, New Mexico); LaRico Juan Treadwell (Albuquerque, New Mexico); Andrew Vackel (Albuquerque, New Mexico) |
ABSTRACT | The invention is directed to a method for attaching nanomaterials containing hexagonal lattices to polymer surfaces. For example, carbon nanotubes (CNTs) can be attached to polycarbonate, polyethylene, or epoxy surfaces by amination of the polymer surface, functionalization of the surfaces of CNTs with ester groups, and reacting the aminated surface of the polymer with the ester groups of the functionalized surfaces of the CNTs in an organic solvent to chemically bind the CNTs to the polymer surface. |
FILED | Wednesday, February 17, 2021 |
APPL NO | 17/177470 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/174 (20170801) C01B 2202/02 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/14 (20130101) C08F 8/32 (20130101) Original (OR) Class C08F 10/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/1477 (20130101) C08G 59/1494 (20130101) C08G 64/42 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566203 | Eryilmaz et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Osman Levent Eryilmaz (Plainfield, Illinois); Vanessa DaSilva (Countryside, Illinois); Ali Erdemir (Naperville, Illinois) |
ABSTRACT | A non-stoichiometric nanocomposite coating and method of making and using the coating. The non-stoichiometric nanocomposite coating is disposed on a base material, such as a metal or ceramic; and the nanocomposite consists essentially of a matrix of an alloy selected from the group of Cu, Ni, Pd, Pt and Re which are catalytically active for cracking of carbon bonds in oils and greases and a grain structure selected from the group of borides, carbides and nitrides. |
FILED | Friday, September 25, 2020 |
APPL NO | 17/033014 |
ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/22 (20130101) B01J 27/24 (20130101) B01J 37/0201 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 101/02 (20130101) C10M 177/00 (20130101) Original (OR) Class Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2030/06 (20130101) C10N 2060/00 (20130101) C10N 2070/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 30/005 (20130101) C23C 2222/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566392 | Leighton et al. |
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FUNDED BY |
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APPLICANT(S) | LITTORAL POWER SYSTEMS, INC. (New Bedford, Massachusetts) |
ASSIGNEE(S) | Littoral Power Systems, Inc. (New Bedford, Massachusetts) |
INVENTOR(S) | Katherine T. Leighton (Media, Pennsylvania); David J. Duquette, Jr. (Fairhaven, Massachusetts); Chad W. Cox (Brookline, Massachusetts); Mark Graeser (Littleton, Colorado) |
ABSTRACT | A fish passage system having flexible textile materials forming a conduit to transport fish across river barriers encountered during migration. The system can include modular support structures that can be independently secured to riverbeds to form conduit supports, dams, hydropower structures, and the like. |
FILED | Tuesday, May 26, 2020 |
APPL NO | 16/883970 |
ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Hydraulic Engineering E02B 8/085 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566497 | Su et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Jiann-Cherng Su (Albuquerque, New Mexico); Stephen Buerger (Albuquerque, New Mexico); Anirban Mazumdar (Atlanta, Georgia); Adam Foris (Albuquerque, New Mexico) |
ABSTRACT | A modular anti-rotation device for preventing rotation with respect to the central axis of a drilling tool in a borehole and for producing a notch in a borehole surface. The anti-rotation device includes an upper fixture portion and a lower fixture portion in axial alignment. The upper fixture portion and the lower fixture portion are connected by yoke assemblies. Each yoke assembly is connected to the fixture portion and fixture portion at one end, and forming an articulated joint of the upper yoke assembly and the lower yoke assembly at a distal end opposite the first end. A roller is connected at each joint, connecting the upper and lower yoke assemblies. The rollers engage vertically with a borehole surface, the rollers travelling axially, as a drill shaft penetrates into the borehole, the rollers simultaneously preventing radial movement of the anti-rotation device and prevent rotation with respect to the central axis of the borehole. |
FILED | Thursday, August 26, 2021 |
APPL NO | 17/412397 |
ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 4/006 (20130101) E21B 4/18 (20130101) E21B 17/02 (20130101) E21B 17/10 (20130101) E21B 17/1021 (20130101) E21B 17/1057 (20130101) E21B 17/1078 (20130101) E21B 43/106 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566809 | Francis et al. |
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FUNDED BY |
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APPLICANT(S) | Robert Bosch GmbH (Stuttgart, Germany) |
ASSIGNEE(S) | Robert Bosch GmbH (Stuttgart, Germany) |
INVENTOR(S) | Jonathan Francis (Pittsburgh, Pennsylvania); Sirajum Munir (Pittsburgh, Pennsylvania); Matias Alberto Quintana Rosales (Singapore, Singapore) |
ABSTRACT | Occupant thermal comfort may be inferred and improved using body shape information. Height, weight, and shoulder circumference of an occupant of a room may be obtained using a depth sensor. A model may be utilized that is trained on a dataset including information reflecting of occupant comfort within the room versus temperature, the model receiving, as inputs, the height, the weight, and the shoulder circumference of the occupant and environmental information and outputting a comfort class. A temperature set-point for is identified which the room occupant is identified by the model as having the comfort class being indicative of user comfort. Heating, ventilation, and air conditioning (HVAC) controls are adjusted for the room to the identified temperature set-point. |
FILED | Tuesday, November 12, 2019 |
APPL NO | 16/681131 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/49 (20180101) F24F 11/64 (20180101) Original (OR) Class F24F 2120/10 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566853 | Bahar et al. |
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FUNDED BY |
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APPLICANT(S) | Xergy Inc. (Harrington, Delaware) |
ASSIGNEE(S) | FFI IONIX IP, INC. (Wilmington, Delaware) |
INVENTOR(S) | Bamdad Bahar (Georgetown, Delaware); Peter Mark Golben (Florida, New York); William Parmelee (Dover, Delaware) |
ABSTRACT | A heat exchanger incorporates a metal hydride heat exchanger and mitigates the fluid mixing process, and thus greatly improves the heat transfer efficiency and heat recovery processes. The metal hydride heat exchanger has a container for the metal hydride that has a large aspect ratio. A plurality of high aspect container for the metal hydride may be coupled with a manifold. |
FILED | Friday, December 21, 2018 |
APPL NO | 16/231310 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 11/005 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 17/12 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/003 (20130101) F28D 20/0056 (20130101) Original (OR) Class F28D 21/00 (20130101) F28D 21/0015 (20130101) F28D 2020/0078 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567015 | Klein |
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FUNDED BY |
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APPLICANT(S) | Boulder Environmental Sciences and Technology (Boulder, Colorado) |
ASSIGNEE(S) | Boulder Environmental Sciences and Technology (Boulder, Colorado) |
INVENTOR(S) | Marian Klein (Boulder, Colorado) |
ABSTRACT | A system for passive microwave remote sensing using at least one microwave radiometer includes a fixed body portion and a mobile body portion. The mobile body portion is configured for rotatably coupling with the fixed body portion for rotation about a rotation axis. The mobile body portion is configured for supporting the microwave radiometer therein such that the microwave radiometer rotates about the rotation axis when the mobile body portion is rotated about the rotation axis such that a polarization axis of the radiometer is aligned with an earth axis. The fixed body portion includes a motor mechanism for effecting rotation of the mobile body portion. In an embodiment, the mobile body portion includes a plurality of body section, each body section being configured for supporting a microwave radiometer therein. In another embodiment, each one of the plurality of body sections is configured to be interchangeably coupled with each other. |
FILED | Wednesday, December 30, 2020 |
APPL NO | 17/138268 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) G01N 22/04 (20130101) Original (OR) Class G01N 33/2823 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 25/04 (20130101) G01R 27/04 (20130101) G01R 27/22 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/17 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567035 | Katz et al. |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Howard E. Katz (Owing Mills, Maryland); Hui Li (Baltimore, Maryland) |
ABSTRACT | A ratiometric vapor sensor is described that includes a first sensor and a second sensor. The first sensor includes a first semiconductor component comprising a vapor-sensitive semiconducting organic compound, while the second sensor includes a second semiconductor component comprising a modified vapor-sensitive semiconducting organic compound including a modifying organic group. The ratiometric vapor sensor can be used to detect the presence of a vapor such as nitrogen dioxide, and determine the concentration of the vapor by comparing the outputs of electrodes connected to the first and second sensor. |
FILED | Wednesday, May 09, 2018 |
APPL NO | 16/612533 |
ART UNIT | 2814 — Semiconductors/Memory |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4143 (20130101) Original (OR) Class G01N 33/0037 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/098 (20130101) H01L 27/283 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567038 | Sinha et al. |
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FUNDED BY |
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APPLICANT(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Dipen N. Sinha (Bay Shore, New York); Cristian Pantea (Los Alamos, New Mexico) |
ABSTRACT | Described are an apparatus, computer program product, and associated methods for shaped waveform acoustic interrogation of substances and materials to determine one or more properties of the materials or substances. In some embodiments, a shaped waveform is formed by summing two or more different waveforms and an acoustic wave is generated according to the shaped waveform. The acoustic wave is transmitted by one or more transmitting transducers through the substance or material and received by one or more receiving transducers. The shaped waveform acoustic wave can have a duration or a period that is less than about 20 μs and can comprise predetermined frequency content. Characteristics of the shaped waveform acoustic wave, as received at the receiving transducer(s), including characteristics such as amplitude, frequency, time of flight, etc., can be associated with said one or more properties of the substance or material to provide for real-time monitoring of these properties. |
FILED | Monday, September 28, 2020 |
APPL NO | 17/035483 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/667 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 9/24 (20130101) G01N 29/02 (20130101) G01N 29/30 (20130101) G01N 29/348 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567767 | Cain, III et al. |
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FUNDED BY |
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APPLICANT(S) | Marvell Asia Pte, Ltd. (Singapore, Singapore); Cray Inc. (Seattle, Washington) |
ASSIGNEE(S) | MARVELL ASIA PTE, LTD. (Singapore, Singapore); CRAY INC. (Seattle, Washington) |
INVENTOR(S) | Harold Wade Cain, III (Raleigh, North Carolina); Rabin Andrew Sugumar (Sunnyvale, California); Nagesh Bangalore Lakshminarayana (San Jose, California); Daniel Jonathan Ernst (West St. Paul, Minnesota); Sanyam Mehta (Hopkins, Minnesota) |
ABSTRACT | A system for processing gather and scatter instructions can implement a front-end subsystem, a back-end subsystem, or both. The front-end subsystem includes a prediction unit configured to determine a predicted quantity of coalesced memory access operations required by an instruction. A decode unit converts the instruction into a plurality of access operations based on the predicted quantity, and transmits the plurality of access operations and an indication of the predicted quantity to an issue queue. The back-end subsystem includes a load-store unit that receives a plurality of access operations corresponding to an instruction, determines a subset of the plurality of access operations that can be coalesced, and forms a coalesced memory access operation from the subset. A queue stores multiple memory addresses for a given load-store entry to provide for execution of coalesced memory accesses. |
FILED | Thursday, July 30, 2020 |
APPL NO | 16/944141 |
ART UNIT | 2183 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 9/30043 (20130101) Original (OR) Class G06F 9/30145 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567771 | Cain, III et al. |
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FUNDED BY |
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APPLICANT(S) | Marvell Asia Pte, Ltd. (Singapore, Singapore) |
ASSIGNEE(S) | Marvell Asia PTE, LTD. (Singapore, Singapore); Cray Inc. (Seattle, Washington) |
INVENTOR(S) | Harold Wade Cain, III (Raleigh, North Carolina); Nagesh Bangalore Lakshminarayana (San Jose, California); Daniel Jonathan Ernst (West St. Paul, Minnesota); Sanyam Mehta (Hopkins, Minnesota) |
ABSTRACT | A system for processing gather and scatter instructions can implement a front-end subsystem, a back-end subsystem, or both. The front-end subsystem includes a prediction unit configured to determine a predicted quantity of coalesced memory access operations required by an instruction. A decode unit converts the instruction into a plurality of access operations based on the predicted quantity, and transmits the plurality of access operations and an indication of the predicted quantity to an issue queue. The back-end subsystem includes a load-store unit that receives a plurality of access operations corresponding to an instruction, determines a subset of the plurality of access operations that can be coalesced, and forms a coalesced memory access operation from the subset. A queue stores multiple memory addresses for a given load-store entry to provide for execution of coalesced memory accesses. |
FILED | Thursday, July 30, 2020 |
APPL NO | 16/944146 |
ART UNIT | 2184 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 9/546 (20130101) G06F 9/3834 (20130101) G06F 9/30043 (20130101) G06F 9/30047 (20130101) G06F 9/30145 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11568656 | Mohan et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Kadri Aditya Mohan (Newark, California); Kyle Champley (Pleasanton, California) |
ABSTRACT | A system for generating a 3D segmentation of a target volume is provided. The system accesses views of an X-ray scan of a target volume. The system applies a 2D CNN to each view to generate a 2D multi-channel feature vector for each view. The system applies a space carver to generate a 3D channel volume for each channel based on the 2D multi-channel feature vectors. The system then applies a linear combining technique to the 3D channel volumes to generate a 3D multi-label map that represents a 3D segmentation of the target volume. |
FILED | Friday, September 25, 2020 |
APPL NO | 17/032377 |
ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6232 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 2207/10116 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) Image or Video Recognition or Understanding G06V 20/64 (20220101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11568766 | Ziock et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Klaus-Peter Ziock (Oak Ridge, Tennessee); William R. Ray (Oak Ridge, Tennessee); James R. Younkin (Oak Ridge, Tennessee); Brandon R. Longmire (Oak Ridge, Tennessee) |
ABSTRACT | A fiber Bragg grating (FBG) security component for single-party and multi-party monitoring is provided. The security component includes an optical fiber having a plurality of Bragg gratings. The Bragg gratings provide a spectral response that is randomized based on the manufacture of the security component. For single-party use, the spectral response provides a reproducible spectral signature when interrogated with an optical signal. For multi-party use, each party applies a known optical interrogation signal to the security component and applies an external stress known only to the respective monitoring party. The resulting shift in the spectral signature is unique to each monitoring party, making it extremely difficult to successfully counterfeit the security component's response for all such parties. |
FILED | Tuesday, April 06, 2021 |
APPL NO | 17/223616 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/35316 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/3206 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/246 (20130101) Displaying; Advertising; Signs; Labels or Name-plates; Seals G09F 3/0376 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569431 | Eichenfield et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Matt Eichenfield (Albuquerque, New Mexico); Andrew Jay Leenheer (Albuquerque, New Mexico); Paul Stanfield (Albuquerque, New Mexico) |
ABSTRACT | A CMOS-compatible actuator platform for implementing phase, amplitude, and frequency modulation in silicon nitride photonic integrated circuits via piezo-optomechanical coupling using tightly mechanically coupled aluminum nitride actuators is disclosed. The platform, which may be fabricated in a CMOS foundry, enables scalable active photonic integrated circuits for visible wavelengths, and the piezoelectric actuation functions without performance degradation down to cryogenic operating temperatures. A number of devices are possible, including ring modulator devices, phase shifter devices, Mach-Zehnder interferometer devices, directional coupler devices (including tunable directional coupler devices), and acousto-optic modulator and frequency shifter devices, each of which can employ the same AlN actuator platform. As all of these devices can be built on the same AlN actuator platform, numerous optical functions can be implemented on a single die. |
FILED | Monday, August 10, 2020 |
APPL NO | 16/989535 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/3578 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/125 (20130101) G02F 1/0134 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/18 (20130101) H01L 41/083 (20130101) H01L 41/0815 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569432 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Zhong Lin Wang (Atlanta, Georgia); Haiyang Zou (Atlanta, Georgia) |
ABSTRACT | An apparatus comprising a substrate, one or more nanowire pillars, each having a base portion and a tip portion, a first electrode connected to the tip portions of the one or more nanowire pillars, an internal hollow cavity positioned between the substrate and the first electrode, such that at least a portion of each of the one or more nanowire pillars extend through the internal hollow cavity, and a second electrode proximate the first side of the substrate. High-performance broadband photodetectors and other optoelectronics for converting light to electricity with enhanced absorption and carrier collection. |
FILED | Monday, November 16, 2020 |
APPL NO | 17/098779 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1884 (20130101) H01L 31/022466 (20130101) H01L 31/035227 (20130101) H01L 41/27 (20130101) H01L 41/083 (20130101) Original (OR) Class H01L 41/0471 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569513 | Davis |
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FUNDED BY |
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APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Benjamin L. Davis (Los Alamos, New Mexico) |
ABSTRACT | A nonaqueous electrolyte composition for use in a redox flow battery system, comprising: a nonaqueous supporting electrolyte; and a metal ligand complex of formula II: wherein R1, R2, R3, R4 and R6 are each independently H, halogen, alkyl, substituted alkyl, alkoxy, substituted alkoxy, aryloxy, substituted aryloxy, heteroaryloxy, substituted heteroaryloxy, or a polyether, wherein R5 is H, alkyl, or substituted alkyl; and M is a transition metal or zinc. |
FILED | Tuesday, June 01, 2021 |
APPL NO | 17/335989 |
ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/06 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/02 (20130101) Original (OR) Class H01M 8/188 (20130101) H01M 2300/0025 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11569527 | Hu et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | Liangbing Hu (Rockville, Maryland); Eric D. Wachsman (Fulton, Maryland); Boyang Liu (Columbia, Maryland); Lei Zhang (Berwyn Heights, Maryland); Shaomao Xu (College Park, Maryland); Dennis McOwen (Washington, District of Columbia); Chunpeng Yang (Berwyn Heights, Maryland) |
ABSTRACT | The present disclosure describes various types of batteries, including lithium-ion batteries having an anode assembly comprising: an anode comprising a first porous ceramic matrix having pores; and a ceramic separator layer affixed directly or indirectly to the anode; a cathode; an anode-side current collector contacting the anode; and anode active material comprising lithium located within the pores or cathode active material located within the cathode; wherein, the ceramic separator layer is located between the anode and the cathode, no electrically conductive coating on the pores contacts the separator layer, and in a fully charged state, lithium active material in the anode does not contact the separator layer. Also disclosed are methods of making and methods of using such batteries. |
FILED | Thursday, March 26, 2020 |
APPL NO | 16/830285 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/1393 (20130101) H01M 10/0525 (20130101) Original (OR) Class H01M 10/0565 (20130101) H01M 10/0566 (20130101) H01M 50/46 (20210101) H01M 50/434 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
11564393 — Fatty ammonium salt starch complexes as antimicrobials, plant wound, and wood protectants
US 11564393 | Hay et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | William T. Hay (Peoria, Illinois); Gordon W. Selling (Dunlap, Illinois); George F. Fanta (Morton, Illinois); Fred J. Eller (Peoria, Illinois) |
ABSTRACT | Provided herein are fatty-ammonium salt/starch inclusion complexes comprising one or more of a variety of fatty amines. Such complexes can be combined with film-forming agents, such as poly(vinyl) alcohol (PVOH) and plasticizing agents. The inclusion complexes of the present invention can be utilized as antimicrobial agents, preventing microbial growth on organic and inorganic surfaces. In specific embodiments, inclusion complexes of the present invention are applied to vegetable or fruit surfaces in order to impede microbial growth. Inclusion complexes of the present invention can be applied to wood in order to impede microbial growth and insect consumption and to wound dressings. |
FILED | Friday, July 06, 2018 |
APPL NO | 16/028849 |
ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 33/04 (20130101) A01N 33/12 (20130101) A01N 43/16 (20130101) Original (OR) Class A01N 43/16 (20130101) A01N 43/40 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/28 (20130101) A61L 15/42 (20130101) A61L 2300/404 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566116 | Goddard et al. |
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FUNDED BY |
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APPLICANT(S) | Cornell University (Ithaca, New York) |
ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Julie M. Goddard (Ithaca, New York); Joshua Herskovitz (Philadelphia, Pennsylvania) |
ABSTRACT | Disclosed herein are methods of making active, food-grade packaging resins using a reactive extrusion step that involves reacting a polymeric material with a ligand and one of a cross-linking agent and a radical initiator in an extruder, under temperature and pressure conditions effective to cause covalent binding of the ligand to the polymeric material by a linker that is the reaction product of the cross-linking agent or by direct bond formation between the ligand and the polymeric material, and then extruding the active, food-grade packaging resin. Also disclosed are the active packaging resins obtained from such methods, methods of forming food packaging materials from the active packaging resins, the food packaging materials that contain the active packaging resins, and methods of packaging perishable food in those food packaging materials. |
FILED | Wednesday, August 19, 2020 |
APPL NO | 16/997419 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 49/04 (20130101) B29C 49/0005 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) Original (OR) Class C08J 2323/12 (20130101) C08J 2367/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/20 (20130101) C08K 5/0025 (20130101) C08K 5/46 (20130101) C08K 5/175 (20130101) Compositions of Macromolecular Compounds C08L 23/12 (20130101) C08L 67/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567002 | Bae et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Euiwon Bae (West Lafayette, Indiana); Arun K. Bhunia (West Lafayette, Indiana); Edwin Daniel Hirleman (Merced, California); Huisung Kim (West Lafayette, Indiana); Bartlomiej Rajwa (West Lafayette, Indiana); Joseph Paul Robinson (West Lafayette, Indiana); Valery Patsekin (West Lafayette, Indiana) |
ABSTRACT | A system for the identification of micro-organisms includes an irradiation unit adapted to sequentially provide coherent electromagnetic radiation of one or more wavelengths along a common optical path. A holder is adapted to retain a substrate having a surface adapted for growth of a micro-organism colony. A beamsplitter is adapted to direct the coherent electromagnetic radiation from the common optical path towards the retained substrate. An imager is arranged opposite the beamsplitter from the retained substrate and is adapted to obtain images of backward-scattered light patterns from the micro-organism colony irradiated by the respective wavelengths of the directed coherent electromagnetic radiation. Some examples provide radiation of multiple wavelengths and include an imager arranged optically downstream of the retained substrate to obtain images of forward-scattered light patterns from the micro-organism colony irradiated by the wavelengths of radiation. Organism identification methods are also described. |
FILED | Wednesday, September 02, 2020 |
APPL NO | 17/010802 |
ART UNIT | 2886 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) Original (OR) Class G01N 21/51 (20130101) G01N 21/255 (20130101) G01N 2021/4707 (20130101) G01N 2021/4709 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567051 | Gunasekaran et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Sundaram Gunasekaran (Madison, Wisconsin); Yi-Cheng Wang (Madison, Wisconsin) |
ABSTRACT | Nanoreactors comprising a metal precursor in a carrier are provided as well as methods of initiating, methods of preparing, and methods of using nanoreactors. In some embodiments, upon exposure to heat, the metal precursor forms nanoparticles that can be detected, e.g., by detecting a color change in the nanoreactor and/or by detecting the number and/or size and/or size distribution and/or shape of the nanoparticles. The nanoreactors can be used, in some embodiments, as time-temperature indicators for perishable goods. |
FILED | Tuesday, March 03, 2020 |
APPL NO | 16/807759 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 11566924 | Rufo et al. |
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FUNDED BY |
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APPLICANT(S) | Boston Engineering Corporation (Waltham, Massachusetts) |
ASSIGNEE(S) | Boston Engineering Corporation (Waltham, Massachusetts) |
INVENTOR(S) | Michael Rufo (Hanover, Massachusetts); Michael Conry (Beverly, Massachusetts); Robert Watson (Lowell, Massachusetts) |
ABSTRACT | A technique provides a modular sensing device having multiple separable modules attached end to end. The modules are selectable based on mission requirements, with different modules and combinations thereof selected for different mission types and/or requirements. |
FILED | Friday, January 08, 2021 |
APPL NO | 17/144527 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/003 (20130101) B63B 22/08 (20130101) B63B 2022/006 (20130101) Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 7/26 (20130101) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 11/245 (20130101) Original (OR) Class G01D 21/02 (20130101) Electric Digital Data Processing G06F 8/61 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567015 | Klein |
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FUNDED BY |
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APPLICANT(S) | Boulder Environmental Sciences and Technology (Boulder, Colorado) |
ASSIGNEE(S) | Boulder Environmental Sciences and Technology (Boulder, Colorado) |
INVENTOR(S) | Marian Klein (Boulder, Colorado) |
ABSTRACT | A system for passive microwave remote sensing using at least one microwave radiometer includes a fixed body portion and a mobile body portion. The mobile body portion is configured for rotatably coupling with the fixed body portion for rotation about a rotation axis. The mobile body portion is configured for supporting the microwave radiometer therein such that the microwave radiometer rotates about the rotation axis when the mobile body portion is rotated about the rotation axis such that a polarization axis of the radiometer is aligned with an earth axis. The fixed body portion includes a motor mechanism for effecting rotation of the mobile body portion. In an embodiment, the mobile body portion includes a plurality of body section, each body section being configured for supporting a microwave radiometer therein. In another embodiment, each one of the plurality of body sections is configured to be interchangeably coupled with each other. |
FILED | Wednesday, December 30, 2020 |
APPL NO | 17/138268 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) G01N 22/04 (20130101) Original (OR) Class G01N 33/2823 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 25/04 (20130101) G01R 27/04 (20130101) G01R 27/22 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/17 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567127 | Bienfang |
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FUNDED BY |
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APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
INVENTOR(S) | Joshua Copeland Bienfang (Bethesda, Maryland) |
ABSTRACT | A temporal jitter analyzer analyzes temporal jitter and includes: a time delay controller; a time delay member; a delay measurement circuit; an edge generator in communication with the time delay member and that receives the delayed primary signal from the time delay member and produces a reference signal from the delayed primary signal; a decision circuit in communication with the edge generator and that: receives the reference signal from the edge generator; receives a detector signal; and produces a raw decision signal from the detector signal such that a value of the raw decision signal depends on the reference signal; and a decision circuit readout in communication with the edge generator and the decision circuit and that: receives the reference signal from the edge generator; receives the raw decision signal from the decision circuit; and produces a decision signal from the raw decision signal based on the reference signal. |
FILED | Tuesday, April 06, 2021 |
APPL NO | 17/223554 |
ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/31709 (20130101) Original (OR) Class G01R 31/31727 (20130101) Pulse Technique H03K 5/133 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
US 11565256 | Reiserer et al. |
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FUNDED BY |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
INVENTOR(S) | Ronald S. Reiserer (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); Philip C. Samson (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Michael Geuy (Nashville, Tennessee); Lisa J. McCawley (Nashville, Tennessee); John P. Wikswo (Brentwood, Tennessee) |
ABSTRACT | Microfluidic systems, pumps, valves and applications of the same are provided. The microfluidic system may be a pump or a valve having a fluidic chip and an actuator controlling the opening and closing of the fluidic channel in the fluidic chip. The actuator may be disposed to tilt from the fluidic chip, forming a tilted-rotor peristaltic pump. Alternatively, the actuator may be a rolling ball actuator, and different fluidic chips may be used in different applications. For example, the fluidic chip may be a spiral pump chip having spiral channels, a rotary peristaltic pump chip having multiple output channels, or a multi-port valve chip having one port interconnected with multiple different ports. An analytical valve chip may switchably interconnect bioreactor and rinse/calibration input channels to sensor and waste output channels. The actuator of a random-access valve can move from one valve position to another without opening or closing intermediate ones. |
FILED | Monday, June 29, 2020 |
APPL NO | 17/623350 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) Original (OR) Class B01L 2300/123 (20130101) B01L 2300/0627 (20130101) B01L 2400/0644 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/1261 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/163 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566229 | Thomson et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | James A. Thomson (Madison, Wisconsin); Srikumar Sengupta (Madison, Wisconsin) |
ABSTRACT | Methods for derivation, culture, and maturation of small hepatic progenitor cells are described. |
FILED | Friday, August 30, 2019 |
APPL NO | 16/557404 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/407 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) Original (OR) Class C12N 2500/30 (20130101) C12N 2501/11 (20130101) C12N 2501/33 (20130101) C12N 2501/39 (20130101) C12N 2501/40 (20130101) C12N 2502/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11567035 | Katz et al. |
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FUNDED BY |
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APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
INVENTOR(S) | Howard E. Katz (Owing Mills, Maryland); Hui Li (Baltimore, Maryland) |
ABSTRACT | A ratiometric vapor sensor is described that includes a first sensor and a second sensor. The first sensor includes a first semiconductor component comprising a vapor-sensitive semiconducting organic compound, while the second sensor includes a second semiconductor component comprising a modified vapor-sensitive semiconducting organic compound including a modifying organic group. The ratiometric vapor sensor can be used to detect the presence of a vapor such as nitrogen dioxide, and determine the concentration of the vapor by comparing the outputs of electrodes connected to the first and second sensor. |
FILED | Wednesday, May 09, 2018 |
APPL NO | 16/612533 |
ART UNIT | 2814 — Semiconductors/Memory |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4143 (20130101) Original (OR) Class G01N 33/0037 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/098 (20130101) H01L 27/283 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 11564409 | Lundberg |
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FUNDED BY |
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APPLICANT(S) | Brock M. Lundberg (Osseo, Wisconsin) |
ASSIGNEE(S) | |
INVENTOR(S) | Brock M. Lundberg (Osseo, Wisconsin) |
ABSTRACT | A composition of matter is used as an ingredient in consumable products (for humans and pets) comprising at least 0.005% by weight and preferably 1-30% by weight of highly refined cellulose fiber having at least 15% by total weight of the highly refined cellulose material of an oil-based flavoring or aroma-producing material, the composition of matter being provided as a free-flowing, dry-feel particulate material having a number average mean particle size of less than 2 mm. |
FILED | Friday, January 10, 2020 |
APPL NO | 16/739314 |
ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 27/12 (20160801) A23L 27/75 (20160801) Original (OR) Class A23L 33/24 (20160801) Shaping or Working of Foodstuffs, Not Fully Covered by a Single Other Subclass A23P 20/105 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11565979 | Temme et al. |
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FUNDED BY |
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APPLICANT(S) | Pivot Bio, Inc. (Berkeley, California) |
ASSIGNEE(S) | Pivot Bio, Inc. (Berkeley, California) |
INVENTOR(S) | Karsten Temme (Oakland, California); Alvin Tamsir (San Francisco, California); Sarah Bloch (Emeryville, California); Rosemary Clark (El Cerrito, California); Emily Tung (Milbrae, California); Kevin Hammill (Danville, California); Douglas Higgins (Berkeley, California); Austin Davis-Richardson (San Francisco, California) |
ABSTRACT | Methods and systems are provided for generating and utilizing a bacterial composition that comprises at least one genetically engineered bacterial strain that fixes atmospheric nitrogen in an agricultural system that has been fertilized with more than 20 lbs of Nitrogen per acre. |
FILED | Thursday, November 15, 2018 |
APPL NO | 16/192738 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 3/00 (20130101) A01H 6/4684 (20180501) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/20 (20200101) A01N 63/20 (20200101) A01N 63/20 (20200101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/04 (20130101) C12N 1/20 (20130101) C12N 1/205 (20210501) C12N 15/52 (20130101) C12N 15/70 (20130101) C12N 15/111 (20130101) C12N 15/743 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/01 (20210501) C12R 2001/07 (20210501) C12R 2001/22 (20210501) C12R 2001/025 (20210501) C12R 2001/065 (20210501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11570420 | Redden |
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FUNDED BY |
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APPLICANT(S) | Blue River Technology Inc. (Sunnyvale, California) |
ASSIGNEE(S) | Blue River Technology Inc. (Sunnyvale, California) |
INVENTOR(S) | Lee Kamp Redden (Palo Alto, California) |
ABSTRACT | Described are methods for identifying the in-field positions of plant features on a plant by plant basis. These positions are determined based on images captured as a vehicle (e.g., tractor, sprayer, etc.) including one or more cameras travels through the field along a row of crops. The in-field positions of the plant features are useful for a variety of purposes including, for example, generating three-dimensional data models of plants growing in the field, assessing plant growth and phenotypic features, determining what kinds of treatments to apply including both where to apply the treatments and how much, determining whether to remove weeds or other undesirable plants, and so on. |
FILED | Thursday, June 30, 2022 |
APPL NO | 17/853925 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6277 (20130101) Image Data Processing or Generation, in General G06T 7/593 (20170101) G06T 2207/10021 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30252 (20130101) Image or Video Recognition or Understanding G06V 20/38 (20220101) G06V 2201/12 (20220101) Pictorial Communication, e.g Television H04N 13/128 (20180501) H04N 13/204 (20180501) Original (OR) Class H04N 13/239 (20180501) H04N 13/243 (20180501) H04N 13/271 (20180501) H04N 2013/0081 (20130101) H04N 2013/0092 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 11565790 | Schiller et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
INVENTOR(S) | Noah H. Schiller (Yorktown, Virginia); Nikolas S. Zawodny (Williamsburg, Virginia); Kyle A. Pascioni (Virginia Beach, Virginia); Stephen A. Rizzi (Newport News, Virginia) |
ABSTRACT | A low-noise multi-propeller system includes at least two propellers, each propeller including at least two blades. The propellers rotate in a first direction and define an angular phase relative to one another. A drive system corotates the propellers at substantially equal rotational rates in the first direction. The propellers are substantially phase-locked at a predefined relative phase offset that reduces the overall sound power of the fundamental tone at a blade passage frequency. |
FILED | Wednesday, October 09, 2019 |
APPL NO | 16/597499 |
ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 11/50 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11566511 | Seah et al. |
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FUNDED BY |
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APPLICANT(S) | CHEVRON U.S.A. INC. (San Ramon, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | Chevron U.S.A. Inc. (San Ramon, California); California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Robert Kwan Meng Seah (Cypress, Texas); Hailing An (Houston, Texas); Thomas E. O'Donnell (Houston, Texas); Darmindra Arumugam (Pasadena, California) |
ABSTRACT | A magneto-quasistatic field may be used to align hydrogen of materials within a structure and/or to disrupt the alignment of hydrogen of materials within the structure. Realignment of the hydrogen after the disruption may cause emission of energy from the hydrogen. The characteristic(s) of the energy may be detected and used to generate image(s) of interior portion(s) of the structure. |
FILED | Wednesday, November 04, 2020 |
APPL NO | 17/089539 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 47/0025 (20200501) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/38 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/18 (20130101) G01V 3/38 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 11567207 | Che et al. |
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FUNDED BY |
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APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
INVENTOR(S) | Erzhuo Che (Corvallis, Oregon); Michael Olsen (Corvallis, Oregon) |
ABSTRACT | A computer implemented scheme for a light detection and ranging (LIDAR) system where point cloud feature extraction and segmentation by efficiently is achieved by: (1) data structuring; (2) edge detection; and (3) region growing. |
FILED | Thursday, July 30, 2020 |
APPL NO | 16/943991 |
ART UNIT | 2488 — Recording and Compression |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4804 (20130101) G01S 17/89 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/13 (20170101) G06T 7/136 (20170101) G06T 7/174 (20170101) G06T 7/187 (20170101) G06T 2207/10028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 11564854 | Cooper et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Aftairs (Washington, District of Columbia) |
INVENTOR(S) | Rory Alan Cooper (Gibsonia, Pennsylvania); Chengshiu Chung (Pittsburgh, Pennsylvania); Garrett G. Grindle (Pittsburgh, Pennsylvania); Rosemarie Cooper (Gibsonia, Pennsylvania); Sathish Andrea Sundaram (Pittsburgh, Pennsylvania) |
ABSTRACT | A wheelchair system includes a wheelchair including a plurality of force sensors including at least three force sensors. A rigid seat pan is placed in contact with each the plurality of force sensors at a different position on the rigid seat pan so that the rigid seat pan does not contact the frame and forces on the rigid seat pan are transferred to the plurality of force sensors. Each of the plurality of force sensors is in communicative connection with a processor system. A memory system is in communicative connection and an interface system is in connection with the processor system and a user interface system in communicative connection with the processor system. Instructions stored on the memory system are executable by the processor system to determine a value of a variable related to a distribution of force on the rigid seat pan over time. |
FILED | Thursday, July 11, 2019 |
APPL NO | 17/259173 |
ART UNIT | 3618 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/128 (20161101) A61G 5/1043 (20130101) A61G 5/1091 (20161101) Original (OR) Class A61G 2203/32 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/30 (20180101) G16H 40/63 (20180101) G16H 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 11567950 | Swaminathan et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
INVENTOR(S) | Ashwin Swaminathan (San Diego, California); Yinian Mao (San Diego, California); Guan-Ming Su (Fremont, California); Hongmei Gou (Germantown, Maryland); Avinash Varna (Greenbelt, Maryland); Shan He (Plainsboro, New Jersey); Min Wu (Clarksville, Maryland); Douglas W. Oard (College Park, Maryland) |
ABSTRACT | A confidentiality preserving system and method for performing a rank-ordered search and retrieval of contents of a data collection. The system includes at least one computer system including a search and retrieval algorithm using term frequency and/or similar features for rank-ordering selective contents of the data collection, and enabling secure retrieval of the selective contents based on the rank-order. The search and retrieval algorithm includes a baseline algorithm, a partially server oriented algorithm, and/or a fully server oriented algorithm. The partially and/or fully server oriented algorithms use homomorphic and/or order preserving encryption for enabling search capability from a user other than an owner of the contents of the data collection. The confidentiality preserving method includes using term frequency for rank-ordering selective contents of the data collection, and retrieving the selective contents based on the rank-order. |
FILED | Friday, December 04, 2020 |
APPL NO | 17/112874 |
ART UNIT | 2161 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 16/48 (20190101) G06F 16/951 (20190101) G06F 16/3335 (20190101) G06F 16/24578 (20190101) Original (OR) Class G06F 21/6218 (20130101) G06F 21/6227 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) H04L 9/3236 (20130101) H04L 2209/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
US 11565256 | Reiserer et al. |
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FUNDED BY |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
INVENTOR(S) | Ronald S. Reiserer (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); Philip C. Samson (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Michael Geuy (Nashville, Tennessee); Lisa J. McCawley (Nashville, Tennessee); John P. Wikswo (Brentwood, Tennessee) |
ABSTRACT | Microfluidic systems, pumps, valves and applications of the same are provided. The microfluidic system may be a pump or a valve having a fluidic chip and an actuator controlling the opening and closing of the fluidic channel in the fluidic chip. The actuator may be disposed to tilt from the fluidic chip, forming a tilted-rotor peristaltic pump. Alternatively, the actuator may be a rolling ball actuator, and different fluidic chips may be used in different applications. For example, the fluidic chip may be a spiral pump chip having spiral channels, a rotary peristaltic pump chip having multiple output channels, or a multi-port valve chip having one port interconnected with multiple different ports. An analytical valve chip may switchably interconnect bioreactor and rinse/calibration input channels to sensor and waste output channels. The actuator of a random-access valve can move from one valve position to another without opening or closing intermediate ones. |
FILED | Monday, June 29, 2020 |
APPL NO | 17/623350 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) Original (OR) Class B01L 2300/123 (20130101) B01L 2300/0627 (20130101) B01L 2400/0644 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/1261 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/163 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 11564522 | Yessin et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
INVENTOR(S) | Gabriel Michael Yessin (Arlington, Virginia); William Albert Tartal (Baltimore, Maryland); Joram Shenhar (Fairfax, Virginia); Joel Dewnandan (Bladensburg, Maryland) |
ABSTRACT | Systems, devices, and techniques for producing audio for, or adding audio capability to, a collection box for delivery items that includes a user-operated door for putting items into the collection box. The system can include a processing subsystem, an audio transducer, a trigger device that is connected to, or that is part of, the door of the collection device, and a sensor. The sensor detects the trigger device when the trigger device is in close proximity (e.g., in contact), and the sensor is positioned such that it is in close proximity with the trigger device when the door is closed. In response to the trigger device moving out of close proximity, the sensor generates a signal to the processing system. In response, the processing system generates an audio signal that is converted to sound by the audio transducer, which can be heard outside of the collection box. |
FILED | Wednesday, December 11, 2019 |
APPL NO | 16/710613 |
ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Household or Table Equipment A47G 29/22 (20130101) A47G 29/1207 (20130101) A47G 29/1218 (20130101) A47G 29/1225 (20130101) Original (OR) Class A47G 29/1251 (20170801) A47G 2029/1226 (20130101) A47G 2200/08 (20130101) A47G 2200/066 (20130101) A47G 2200/143 (20130101) A47G 2200/166 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 11569367 | Son et al. |
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FUNDED BY |
|
APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
INVENTOR(S) | Kyung-Ah Son (Malibu, California); Jeong-Sun Moon (Moorpark, California); Hwa Chang Seo (Malibu, California) |
ABSTRACT | A field effect transistor includes a substrate, a passivation layer on the substrate forming a passivated substrate, wherein the passivation layer is inert to XeF2, and a graphene lateral heterostructure field effect transistor (LHFET) on the passivated substrate. |
FILED | Tuesday, April 27, 2021 |
APPL NO | 17/242276 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/223 (20130101) H01L 21/0228 (20130101) H01L 21/02178 (20130101) H01L 21/02181 (20130101) H01L 21/02205 (20130101) H01L 21/02381 (20130101) H01L 21/02488 (20130101) H01L 21/02527 (20130101) H01L 21/02617 (20130101) H01L 27/1218 (20130101) H01L 27/1222 (20130101) H01L 29/167 (20130101) H01L 29/401 (20130101) H01L 29/1606 (20130101) H01L 29/4908 (20130101) H01L 29/66045 (20130101) Original (OR) Class H01L 29/78603 (20130101) H01L 29/78684 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, January 31, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230131.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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