FedInvent™ Patents

Patent Details for Tuesday, February 21, 2023 

This page was updated on Tuesday, February 21, 2023 at 10:47 PM GMT

Department of Health and Human Services (HHS) 

US 11582970 Melander et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina)
ASSIGNEE(S) North Carolina State University (Raleigh, North Carolina)
INVENTOR(S) Christian Melander (Raleigh, North Carolina);  David Kendall Jung (Durham, North Carolina);  Samuel Onofre Reyes (Cary, North Carolina)
ABSTRACT Provided are 2-aminoimidazole-phenyl derivative compounds of Formula (I): which compounds are useful in methods of controlling microbial growth, such as by enhancing the effects of an antibiotic administered in combination with the compound. Compositions including these compounds, devices including these compounds, and methods of using the same are also provided.
FILED Thursday, March 08, 2018
APPL NO 16/492722
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 47/30 (20130101) Original (OR) Class
A01N 47/32 (20130101)
A01N 47/36 (20130101)

Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations
A01P 1/00 (20210801)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4168 (20130101)
A61K 31/4178 (20130101)
A61K 31/4184 (20130101)
A61K 31/4439 (20130101)
A61K 31/5377 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/232 (20130101)
A61L 2202/24 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Heterocyclic Compounds
C07D 233/88 (20130101)
C07D 235/30 (20130101)
C07D 401/12 (20130101)
C07D 403/12 (20130101)
C07D 405/12 (20130101)
C07D 409/12 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583178 Prusky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Burke Neurological Institute (White Plains, New York)
ASSIGNEE(S) Burke Neurological Institute (White Plains, New York)
INVENTOR(S) Glen Prusky (White Plains, New York);  Scott William Joseph Mooney (New York, New York);  Nicholas Jeremy Hill (White Plains, New York)
ABSTRACT Methods, systems and devices for determining contrast sensitivity function in a subject without requiring perceptual report by the subject.
FILED Wednesday, October 23, 2019
APPL NO 16/661596
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/022 (20130101) Original (OR) Class
A61B 3/0091 (20130101)
A61B 3/113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583203 Halpern
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Howard J. Halpern (Chicago, Illinois)
ASSIGNEE(S)
INVENTOR(S) Howard J. Halpern (Chicago, Illinois)
ABSTRACT The present invention provides an apparatus and a corresponding method useful for electron paramagnetic resonance imaging, in situ and in vivo, using high-isolation transmit/receive (TX/RX) coils, which, in some embodiments, provide microenvironmental images that are representative of particular internal structures in the human body and spatially resolved images of tissue/cell protein signals responding to conditions (such as hypoxia) that show the temporal sequence of certain biological processes, and, in some embodiments, that distinguish malignant tissue from healthy tissue. In some embodiments, the TX/RX coils are in a surface, volume or surface-volume configuration. In some embodiments, the transmit coils are oriented to generate an RF magnetic field in directions substantially orthogonal to a static gradient field, and the receive coils are oriented to sense RF EPR signal in directions substantially orthogonal to the transmitted field and to the static field, to minimize coupling of the transmitted signal to the receive coils.
FILED Tuesday, February 25, 2020
APPL NO 16/801021
ART UNIT 2896 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/60 (20130101)
G01R 33/341 (20130101)
G01R 33/3607 (20130101)
G01R 33/3621 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/104 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583239 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Service (Bethesda, Maryland)
INVENTOR(S) Xiaosong Wang (Rockville, Maryland);  Yifan Peng (Bethesda, Maryland);  Le Lu (Bethesda, Maryland);  Zhiyong Lu (Bethesda, Maryland);  Ronald M. Summers (Potomac, Maryland)
ABSTRACT A new chest X-ray database, referred to as “ChestX-ray8”, is disclosed herein, which comprises over 100,000 frontal view X-ray images of over 32,000 unique patients with the text-mined eight disease image labels (where each image can have multi-labels), from the associated radiological reports using natural language processing. We demonstrate that these commonly occurring thoracic diseases can be detected and spatially-located via a unified weakly supervised multi-label image classification and disease localization framework, which is validated using our disclosed dataset.
FILED Monday, March 26, 2018
APPL NO 16/495012
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/5217 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6259 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)

Image Data Processing or Generation, in General
G06T 7/0014 (20130101)
G06T 2207/10116 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30061 (20130101)
G06T 2210/12 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/20 (20180101)
G16H 50/20 (20180101)
G16H 50/70 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583253 Foster et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) FUJIFILM SonoSite, Inc. (Bothell, Washington);  Sunnybrook Research Institute (Toronto, Canada)
ASSIGNEE(S) FUJIFILM SONOSITE, INC. (Bothell, Washington);  SUNNYBROOK RESEARCH INSTITUTE (Toronto, Canada)
INVENTOR(S) F. Stuart Foster (Toronto, Canada);  Desmond Hirson (Thornhill, Canada);  Nicholas Christopher Chaggares (Whitby, Canada);  Emmanuel W. Cherin (Toronto, Canada);  Jianhua Yin (Scarborough, Canada);  Jing Yang (Toronto, Canada);  Christine Demore (Toronto, Canada)
ABSTRACT A dual frequency transducer array includes one or more low frequency transducer arrays and a high frequency transducer array. Unfocused ultrasound such as plane waves are transmitted by the one or more low frequency transducer arrays in a number of different directions into an imaging region of the high frequency transducer array. High frequency echo signals produced by excited contrast agent in the imaging region are received by the high frequency transducer array to produce a contrast agent image. In another embodiment, the high frequency transducer produces unfocused ultrasound to excite the contrast agent in the imaging region and the low frequency transducer(s) receives low frequency echo signals from the excited contrast agent. A tissue image is created from echo signals received by the high or low frequency transducer. Echo data from the tissue image and the contrast agent image are combined to produce a combined tissue/contrast agent image.
FILED Tuesday, August 28, 2018
APPL NO 16/115325
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/14 (20130101)
A61B 8/481 (20130101)
A61B 8/4477 (20130101)
A61B 8/4494 (20130101) Original (OR) Class
A61B 8/5207 (20130101)
A61B 8/5246 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/52039 (20130101)
G01S 7/52074 (20130101)
G01S 15/8915 (20130101)
G01S 15/8952 (20130101)
G01S 15/8995 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583299 Maxwell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Washington through its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) University of Washington through its Center for Commercialization (Seattle, Washington)
INVENTOR(S) Adam D. Maxwell (Woodinville, Washington);  Bryan W. Cunitz (Seattle, Washington);  Wayne Kreider (Seattle, Washington);  Oleg A. Sapozhnikov (Seattle, Washington);  Ryan S. Hsi (Seattle, Washington);  Michael R. Bailey (Seattle, Washington)
ABSTRACT A method for attempting to fragment or comminute an object in a body using ultrasound includes producing a burst wave lithotripsy (BWL) waveform by a therapy transducer. The BWL waveform is configured to fragment or comminute the object. The BWL waveform includes a first burst of continuous ultrasound cycles and a second burst of continuous ultrasound cycles. A burst frequency corresponds to a frequency of repeating the bursts of the BWL waveform. The method also includes determining a cycle frequency f of the continuous ultrasound cycles within the first burst and the second burst based on a target fragment size D, where the cycle frequency is:
f(MHz)=0.47/D(mm).
FILED Thursday, March 07, 2019
APPL NO 16/295607
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/22012 (20130101) Original (OR) Class
A61B 2017/22014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583311 Bankiewicz
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Krystof Bankiewicz (Oakland, California)
ABSTRACT The use of stepped cannulas, wherein a step structure creates a backstop to reduce backflow along the cannula body, is known for convection enhanced delivery of agents to the brain and other structures within an animal. Described herein are novel and improved stepped cannula designs wherein the length of the cannula segment between the step and the dispensing outlet is variable and can be controllably adjusted inside the patient during delivery. This advantageously allows the operator to place the cannula step at the optimal position and deliver agents at one or more positions within the target structure.
FILED Monday, July 06, 2020
APPL NO 16/921604
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/12 (20130101)
A61B 17/3417 (20130101)
A61B 17/3421 (20130101) Original (OR) Class
A61B 17/3478 (20130101)
A61B 2017/00991 (20130101)
A61B 2017/3433 (20130101)
A61B 2017/3443 (20130101)
A61B 2017/3454 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/46 (20130101)
A61M 5/158 (20130101)
A61M 5/3286 (20130101)
A61M 2206/20 (20130101)
A61M 2210/0693 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583516 Bachovchin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Boston, Massachusetts)
INVENTOR(S) William W. Bachovchin (Cambridge, Massachusetts);  Hung-sen Lai (Andover, Massachusetts);  Wengen Wu (Winchester, Massachusetts)
ABSTRACT Disclosed are potent immuno-DASH inhibitors and their use in the treatment of cell proliferative diseases.
FILED Thursday, September 07, 2017
APPL NO 16/331181
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/69 (20130101)
A61K 31/69 (20130101)
A61K 31/402 (20130101) Original (OR) Class
A61K 31/4025 (20130101)
A61K 31/4035 (20130101)
A61K 31/4439 (20130101)
A61K 35/13 (20130101)
A61K 39/39 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 37/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583523 Mehrara et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Memorial Sloan Kettering Cancer Center (New York, New York)
ASSIGNEE(S) Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S) Babak Mehrara (Chappaqua, New York);  Jason Gardenier (Altona, New York);  Ira Savetsky (Cedarhurst, New York);  Omer Aras (New York, New York)
ABSTRACT Provided are pharmaceutical compositions and methods of treating or preventing edema, using an anti-T cell agent, an anti-TGF-β1 agent, or an anti-angiotensin agent, preferably a combination of at least two such agents. The pharmaceutical compositions can be formulated for systemic or local administration, and are preferably administered topically.
FILED Tuesday, November 17, 2020
APPL NO 16/950652
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0014 (20130101)
A61K 31/42 (20130101)
A61K 31/277 (20130101)
A61K 31/277 (20130101)
A61K 31/401 (20130101)
A61K 31/401 (20130101)
A61K 31/436 (20130101)
A61K 31/436 (20130101)
A61K 31/4412 (20130101) Original (OR) Class
A61K 31/4418 (20130101)
A61K 31/4418 (20130101)
A61K 38/13 (20130101)
A61K 38/13 (20130101)
A61K 45/06 (20130101)
A61K 47/10 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583525 Sebti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida);  NEW YORK UNIVERSITY (New York, New York)
ASSIGNEE(S) H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida);  NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) Said M. Sebti (Tampa, Florida);  Michele Pagano (New York, New York);  Shafi Kuchay (New York, New York)
ABSTRACT A method is disclosed for treating a cancer in a subject that involves administering to the subject a therapeutically affective amount of a geranylgeranyltransferase I (GGTase I) inhibitor, such as GGTI-2418, wherein the cancer comprises a defective PTEN, a hyperactivated FBXL2, or a low level of IP3R3. In some embodiments, the method further involves administering to the subject a therapeutically affective amount of an Akt inhibitor.
FILED Wednesday, June 06, 2018
APPL NO 16/619994
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/496 (20130101) Original (OR) Class
A61K 31/4985 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57484 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583528 Smith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Child Health and Human Development (NICHD)
Non-Profit Organization (NPO)
Bright Focus Foundation
Massachusetts Lions Eye Research Fund, Inc.
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Lois Smith (West Newton, Massachusetts);  Jean-Sebastien Joyal (Boston, Massachusetts)
ABSTRACT The instant invention provides methods and compositions related to discovery of Free Fatty Acid Receptor 1 (FFA1) as a therapeutic target for treatment or prevention of diseases or disorders of neurons that are characterized by angiogenesis, or of vascular diseases of the eye, retinal degeneration and/or tumors more generally. Therapeutic and/or prophylactic uses and compositions of known FFA1 inhibitors, including small molecules and nucleic acid agents, are described. Methods for identification of novel FFA1 inhibitors are also provided.
FILED Friday, February 17, 2017
APPL NO 15/999535
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/352 (20130101)
A61K 31/513 (20130101) Original (OR) Class
A61K 31/519 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5044 (20130101)
G01N 2800/50 (20130101)
G01N 2800/164 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583556 Moriarity et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota);  Intima Bioscience, Inc. (New York, New York);  The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota);  Intima Bioscience, Inc. (New York, New York);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Branden Moriarity (Shoreview, Minnesota);  Beau Webber (Coon Rapids, Minnesota);  Modassir Choudhry (New York, New York);  R. Scott McIvor (St. Louis Park, Minnesota);  David Largaespada (Mounds View, Minnesota);  Steven A. Rosenberg (Potomac, Maryland);  Douglas C. Palmer (North Bethesda, Maryland);  Nicholas P. Restifo (Chevy Chase, Maryland)
ABSTRACT Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.
FILED Wednesday, August 26, 2020
APPL NO 17/003081
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class

Peptides
C07K 14/4718 (20130101)
C07K 14/7051 (20130101)
C07K 14/7158 (20130101)
C07K 14/70503 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 9/22 (20130101)
C12N 9/96 (20130101)
C12N 15/87 (20130101)
C12N 15/113 (20130101)
C12N 15/907 (20130101)
C12N 2310/20 (20170501)
C12N 2510/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583571 Sopko et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland);  SUMMA HEALTH SYSTEM (Akron, Ohio)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  Summa Health System (Akron, Ohio)
INVENTOR(S) Nikolai Sopko (Baltimore, Maryland);  Trinity Bivalacqua (Baltimore, Maryland);  Marc Penn (Akron, Ohio)
ABSTRACT Stromal Derived Factor-1 (SDF-1) is a small, naturally occurring, potent chemokine with inherent angiogenic, neurogenic, anti-apoptotic protein, which is also a potent stem cell chemoattractant, cardiovascular disease, and other metabolic disturbances. The present invention provides methods for treating erectile dysfunction in a male subject comprising administering to the major pelvic ganglion supplying the cavernous nerves subject compositions comprising SDF-1. SDF-1 promotes stem cell activation, to the major pelvic ganglion supplying the cavernous nerves, helps cell preservation, and prevents adverse penile remodeling. It can be administered as a protein or by gene therapy including but not limited to plasmid DNA, viral transduction, or nanoparticle delivery directly to the penis or to the neurovascular bundle or other pelvic nerve structures during the time of surgery, or before injury, or to treat existing erectile dysfunction.
FILED Friday, May 11, 2018
APPL NO 16/613282
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/185 (20130101)
A61K 38/195 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 15/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583572 Weiss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Michael Weiss (Moreland Hills, Ohio);  Jonathan Pokorski (Cleveland, Ohio)
ABSTRACT An insulin composition comprises an insulin analogue and polymer blend. The insulin analogue contains cysteine substitutions at positions B4 and A10 (to form cystine B4-A10), and one or more additional substitutions selected from the group consisting of: a connecting domain of 5-11 amino acids between insulin A- and B domains; a non-beta-branched amino-acid substitution at position A8; a non-beta-branched acidic or polar side chain at position A14; a halogenic modification of PheB24 at the ortho position; and substitution of lysine at position B29 by Glu, Ala, Val, Ile, Leu, amino-propionic acid, amino-butryic acid, or Norleucine. The insulin analogue is compatible with a process of manufacture that includes one or more steps within the temperature range 90-120° C. The encapsulated insulin analogue may optionally contain free PEG or be PEGylated. The insulin analogue-encapsulated polymer blend may be cast as a microneedle patch for topical administration or as micropellets for subcutaneous injection.
FILED Friday, December 23, 2016
APPL NO 16/065596
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0021 (20130101)
A61K 38/28 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583586 Bradner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
ASSIGNEE(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
INVENTOR(S) James Bradner (Weston, Massachusetts);  Dennis Buckley (Jamaica Plain, Massachusetts);  Georg Winter (Vienna, Austria)
ABSTRACT The present application provides bifunctional compounds which act as protein degradation inducing moieties. The present application also relates to methods for the targeted degradation of endogenous proteins through the use of the bifunctional compounds that link a cereblon-binding moiety to a ligand that is capable of binding to the targeted protein which can be utilized in the treatment of proliferative disorders. The present application also provides methods for making compounds of the application and intermediates thereof.
FILED Monday, September 28, 2020
APPL NO 17/035081
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/454 (20130101)
A61K 47/54 (20170801)
A61K 47/542 (20170801) Original (OR) Class
A61K 47/545 (20170801)
A61K 47/549 (20170801)
A61K 47/554 (20170801)

Heterocyclic Compounds
C07D 401/14 (20130101)
C07D 471/04 (20130101)
C07D 487/04 (20130101)
C07D 495/14 (20130101)

Steroids
C07J 3/005 (20130101)
C07J 43/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583588 Santich et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S) Brian H. Santich (New York, New York);  Mahiuddin Ahmed (New York, New York);  Nai-Kong V. Cheung (New York, New York)
ABSTRACT The present invention relates to compositions and methods employing conjugates that include a self-assembly and disassembly (SADA) polypeptide and a binding domain. The present invention encompasses the recognition that conjugates with a SADA polypeptide have certain improved biological properties. SADA-conjugates are described, along with uses thereof (e.g., as therapeutic or diagnostic agents) and methods of manufacture.
FILED Friday, May 04, 2018
APPL NO 16/609401
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/547 (20170801)
A61K 47/641 (20170801) Original (OR) Class
A61K 51/10 (20130101)
A61K 51/0495 (20130101)
A61K 51/1096 (20130101)

Peptides
C07K 14/4746 (20130101)
C07K 14/7155 (20130101)
C07K 16/44 (20130101)
C07K 16/3084 (20130101)
C07K 2317/92 (20130101)
C07K 2317/94 (20130101)
C07K 2317/622 (20130101)
C07K 2319/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583595 Pan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Wayne State University (Detroit, Michigan)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Zhuo-Hua Pan (Troy, Michigan);  Qi Lu (Detroit, Michigan);  Tushar H. Ganjawala (Canton, Michigan);  JrGang Cheng (Chapel Hill, North Carolina)
ABSTRACT The invention provides nucleic acids and nucleic acid expression vectors containing optimized mGluR6 promoters for expression of transgenes in the retina. The compositions and methods of the invention are useful for expression of gene products to preserve, improve, or restore phototransduction or vision.
FILED Friday, April 26, 2019
APPL NO 16/395839
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 38/1787 (20130101)
A61K 48/0058 (20130101) Original (OR) Class
A61K 48/0075 (20130101)

Peptides
C07K 14/70571 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/67 (20130101)
C12N 15/85 (20130101)
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)
C12N 2830/008 (20130101)
C12N 2830/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583608 Stasko et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Novan, Inc. (Morrisville, North Carolina)
ASSIGNEE(S) Novan, Inc. (Durham, North Carolina)
INVENTOR(S) Nathan Stasko (Chapel Hill, North Carolina);  Susanne Bauman (Durham, North Carolina);  Pranav R. Joshi (Bangalore, India)
ABSTRACT Provided according to some embodiments of the invention are wound dressings that include a polymer matrix and nitric oxide-releasing polysiloxane macromolecules within and/or on the polymer matrix. Also provided are wound dressing kits and methods of using and forming such wound dressings.
FILED Friday, February 02, 2018
APPL NO 15/887649
ART UNIT 3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/44 (20130101) Original (OR) Class
A61L 15/225 (20130101)
A61L 15/225 (20130101)
A61L 15/225 (20130101)
A61L 15/425 (20130101)
A61L 2300/45 (20130101)
A61L 2300/114 (20130101)
A61L 2300/602 (20130101)

Compositions of Macromolecular Compounds
C08L 75/04 (20130101)
C08L 83/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583613 Taboas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Juan M. Taboas (Pittsburgh, Pennsylvania);  Jingming Chen (Pittsburgh, Pennsylvania)
ABSTRACT Described herein are biomaterials, systems, and methods for guiding regeneration of an epiphyseal growth plate or similar interfacial tissue structures. In one aspect, the disclosed technology can include a biologic material that can comprise one or more of a hydrogel carrier for growth factors and MSCs, chondrogenic and immunomodulatory cytokines, microparticles for prolonged and spatially controlled growth factor delivery; and/or porous scaffold providing mechanical support. The implanted material can be applied via various different modalities depending on the nature of the physeal injury. One modality is an injectable hydrogel and another modality is an implantable hydrogel infused scaffold.
FILED Friday, March 03, 2017
APPL NO 16/080220
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101)
A61L 27/20 (20130101)
A61L 27/52 (20130101) Original (OR) Class
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 27/222 (20130101)
A61L 27/3834 (20130101)
A61L 27/3852 (20130101)
A61L 2300/45 (20130101)
A61L 2300/414 (20130101)
A61L 2400/06 (20130101)
A61L 2430/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583627 Forouzandeh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
ASSIGNEE(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
INVENTOR(S) Farzad Forouzandeh (Rochester, New York);  David Borkholder (Canandaigua, New York);  Robert Frisina (Tampa, Florida);  Joseph Walton (Tampa, Florida);  Xiaoxia Zhu (Tampa, Florida)
ABSTRACT In one embodiment, a fluid storage device includes a rigid outer housing that defines a septum cavity, a reservoir cavity, and a channel that extends between the two cavities, the outer housing further defining an outlet in fluid communication with the reservoir cavity, a septum provided within the septum cavity, the septum being made of an elastic polymer and facilitating refilling of the fluid storage device, and a thin, collapsible membrane that does not generate significant restoring forces when it is deformed as fluid is drawn from the reservoir cavity and, therefore, does not completely or partially return to its initial non-deformed shape even if the outlet of the device remains open after doses are administered.
FILED Friday, October 18, 2019
APPL NO 16/657981
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/145 (20130101)
A61M 5/204 (20130101)
A61M 5/14224 (20130101)
A61M 5/14276 (20130101) Original (OR) Class
A61M 5/14593 (20130101)
A61M 39/06 (20130101)
A61M 2039/027 (20130101)
A61M 2039/0072 (20130101)
A61M 2039/0081 (20130101)
A61M 2205/0244 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583853 Yantz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) First Light Diagnostics, Inc. (Chelmsford, Massachusetts)
ASSIGNEE(S) FIRST LIGHT DIAGNOSTICS, INC. (Chelmsford, Massachusetts)
INVENTOR(S) Greg Yantz (Somerville, Massachusetts);  Don Straus (Cambridge, Massachusetts);  Gordon Siek (Somerville, Massachusetts);  Damon Dehart (Bedford, Massachusetts)
ABSTRACT The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.
FILED Friday, August 16, 2019
APPL NO 16/543028
ART UNIT 1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/117 (20130101)
A61B 5/151 (20130101)
A61B 5/157 (20130101)
A61B 5/15113 (20130101)
A61B 5/15186 (20130101)
A61B 5/150022 (20130101)
A61B 5/150213 (20130101)
A61B 5/150221 (20130101)
A61B 5/150274 (20130101)
A61B 5/150305 (20130101)
A61B 5/150343 (20130101)
A61B 5/150351 (20130101)
A61B 5/150412 (20130101)
A61B 5/150503 (20130101)
A61B 5/150786 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5029 (20130101)
B01L 3/5082 (20130101)
B01L 3/502715 (20130101) Original (OR) Class
B01L 3/502761 (20130101)
B01L 7/00 (20130101)
B01L 9/52 (20130101)
B01L 2200/10 (20130101)
B01L 2200/025 (20130101)
B01L 2200/026 (20130101)
B01L 2200/027 (20130101)
B01L 2200/0605 (20130101)
B01L 2300/022 (20130101)
B01L 2300/042 (20130101)
B01L 2300/043 (20130101)
B01L 2300/046 (20130101)
B01L 2300/048 (20130101)
B01L 2300/0654 (20130101)
B01L 2300/0681 (20130101)
B01L 2300/0864 (20130101)
B01L 2400/043 (20130101)
B01L 2400/0406 (20130101)
B01L 2400/0409 (20130101)
B01L 2400/0415 (20130101)
B01L 2400/0457 (20130101)
B01L 2400/0472 (20130101)
B01L 2400/0481 (20130101)
B01L 2400/0677 (20130101)
B01L 2400/0683 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/03 (20130101)
G01N 21/253 (20130101)
G01N 21/6428 (20130101)
G01N 21/6452 (20130101)
G01N 21/6458 (20130101)
G01N 33/54373 (20130101)
G01N 2021/0325 (20130101)
G01N 2021/0346 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584717 Jorgensen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) William L. Jorgensen (Deep River, Connecticut);  Richard J. Bucala (Cos Cob, Connecticut)
ABSTRACT The invention provides novel heterocyclic compounds, pharmaceutical compositions and methods of treatment that modulate levels of MIF expression and treat disorders associated with high or low levels of MIF expression.
FILED Friday, December 21, 2018
APPL NO 16/229069
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 209/18 (20130101) Original (OR) Class
C07D 235/12 (20130101)
C07D 235/24 (20130101)
C07D 249/06 (20130101)
C07D 263/58 (20130101)
C07D 275/04 (20130101)
C07D 307/80 (20130101)
C07D 307/83 (20130101)
C07D 401/04 (20130101)
C07D 401/06 (20130101)
C07D 403/04 (20130101)
C07D 405/06 (20130101)
C07D 413/04 (20130101)
C07D 417/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584718 Shapiro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) David J. Shapiro (Urbana, Illinois);  Paul J. Hergenrother (Champaign, Illinois);  Matthew W. Boudreau (Urbana, Illinois)
ABSTRACT A set of small molecules ERα biomodulators that kill therapy-resistant ERα positive breast, ovarian, and endometrial cancer cells. These small molecules have increased therapeutic potential because of an increased ability to kill therapy-resistant breast cancer cells compared to BHPI and other conventional therapies (endocrine therapies, tamoxifen and fulvestrant/ICI). The new compounds do not only inhibit proliferation of the cancer cells but actually kills them, which prevents reactivation of tumors years later.
FILED Thursday, May 13, 2021
APPL NO 17/319447
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 209/34 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584736 Jacobson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Mental Health (NIMH)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Kenneth A. Jacobson (Silver Spring, Maryland);  Jinha Yu (Gaithersburg, Maryland);  Antonella Ciancetta (Belfast, Ireland);  Zhiwei Wen (Rockville, Maryland);  Young-Hwan Jung (Rockville, Maryland)
ABSTRACT Disclosed are compounds of formulas (I)-(IX) for treating or preventing a disease or disorder responsive to antagonism of a P2Y14R receptor agonist in a mammal in need thereof, wherein R1-R8, X, Y, Z, X′, Y′, Z′, and A are as defined herein, that are useful in treating an inflammatory such as asthma, cystic fibrosis, and sterile inflammation of the kidney.
FILED Monday, February 11, 2019
APPL NO 16/967177
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 11/06 (20180101)

Acyclic or Carbocyclic Compounds
C07C 235/84 (20130101)

Heterocyclic Compounds
C07D 209/20 (20130101)
C07D 211/34 (20130101)
C07D 211/70 (20130101)
C07D 249/06 (20130101)
C07D 401/10 (20130101)
C07D 401/14 (20130101) Original (OR) Class
C07D 409/10 (20130101)
C07D 471/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584744 Fan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF WASHINGTON (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Erkang Fan (Seattle, Washington);  Zhongsheng Zhang (Seattle, Washington);  Wenlin Huang (Seattle, Washington);  Frederick S. Buckner (Seattle, Washington)
ABSTRACT The present disclosure is generally directed to compositions useful in the inhibition of MetRS and methods for treating diseases that are ameliorated by the inhibition of MetRS.
FILED Friday, June 22, 2018
APPL NO 16/625460
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 401/14 (20130101)
C07D 403/06 (20130101)
C07D 471/04 (20130101) Original (OR) Class
C07D 487/04 (20130101)
C07D 519/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584746 Gray et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Nathanael S. Gray (Jamaica Plain, Massachusetts);  Dries De Clercq (Boston, Massachusetts);  Jaebong Jang (Boston, Massachusetts);  Pasi Janne (Needham, Massachusetts);  Ciric To (Boston, Massachusetts);  Michael Eck (Boston, Massachusetts);  Eunyoung Park (Boston, Massachusetts);  David Heppner (Boston, Massachusetts)
ABSTRACT The application relates to a compound having Formula Ia or Ib: or a pharmaceutically acceptable salt, hydrate, or solvate thereof, which modulates the activity of EGFR, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which EGFR plays a role.
FILED Wednesday, February 20, 2019
APPL NO 16/970931
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 243/38 (20130101)
C07D 401/06 (20130101)
C07D 401/14 (20130101)
C07D 403/04 (20130101)
C07D 403/06 (20130101)
C07D 403/14 (20130101)
C07D 417/14 (20130101)
C07D 471/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584760 Nam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CITY OF HOPE (Duarte, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Sangkil Nam (Tujunga, California);  David Horne (Altadena, California);  Larry Eugene Overman (Corona Del Mar, California);  Brad Loertscher (Portage, Michigan)
ABSTRACT Disclosed herein, inter alia, are compositions and methods of using the same for the treatment of cancer.
FILED Wednesday, September 23, 2020
APPL NO 17/030073
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/548 (20130101)
A61K 31/706 (20130101)
A61K 31/706 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 401/12 (20130101)
C07D 487/04 (20130101)
C07D 513/08 (20130101)
C07D 513/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584766 Driver et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) THE TRUSTEES OF INDIANA UNIVERSITY (Indianapolis, Indiana);  THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) THE TRUSTEES OF INDIANA UNIVERSITY (Indianapolis, Indiana);  THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Indiana)
INVENTOR(S) Tom G. Driver (Chicago, Illinois);  Roberto F. Machado (Carmel, Indiana);  Najing Su (Newark, Delaware);  Xinyu Guan (Chicago, Illinois);  Wrickban Mazumdar (Chicago, Illinois);  Kira Ratia (Chicago, Illinois);  Jason Ralph Hickok (Chicago, Illinois);  Angelia Denise Lockett (Indianapolis, Indiana)
ABSTRACT Disclosed herein are compounds that can act as inhibitors of nicotinamide phosphoribosyltransferase (“NAMPT”), and methods for their use in treating or preventing diseases, such as pulmonary arterial hypertension (“PAH”). The compounds described herein can include compounds of Formula (II) and pharmaceutically acceptable salts thereof: wherein the substituents are as described.
FILED Tuesday, February 05, 2019
APPL NO 16/967279
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 401/12 (20130101)
C07D 491/056 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/0816 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584787 List et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida)
ASSIGNEE(S) H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida)
INVENTOR(S) Alan F. List (Tampa, Florida);  Sheng Wei (Tampa, Florida)
ABSTRACT Disclosed are compositions and methods for treating disease or condition caused or exacerbated by S100A9 activity, such as myelodysplastic syndromes (MDS) using a composition comprising an effective amount of a CD33/S100A9 inhibitor.
FILED Tuesday, June 25, 2019
APPL NO 16/451525
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/177 (20130101)
A61K 38/1774 (20130101)
A61K 47/6911 (20170801)
A61K 47/6913 (20170801)

Peptides
C07K 14/705 (20130101)
C07K 14/70503 (20130101) Original (OR) Class
C07K 14/70535 (20130101)
C07K 14/70596 (20130101)
C07K 19/00 (20130101)
C07K 2319/00 (20130101)
C07K 2319/30 (20130101)
C07K 2319/32 (20130101)
C07K 2319/70 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6872 (20130101)
G01N 2333/4727 (20130101)
G01N 2333/70503 (20130101)
G01N 2500/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584789 Chan-Hui et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Theraclone Sciences, Inc. (Seattle, Washington);  International AIDS Vaccine Initiative (New York, New York);  The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) INTERNATIONAL AIDS VACCINE INITIATIVE, INC. (New York, New York);  THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California);  THERACLONE SCIENCES, INC. (Seattle, Washington)
INVENTOR(S) Po-Ying Chan-Hui (Bellevue, Washington);  Steven Frey (Redmond, Washington);  Ole Olsen (Everett, Washington);  Jennifer Mitcham (Redmond, Washington);  Matthew Moyle (Redmond, Washington);  Sanjay K. Phogat (Frederick, Maryland);  Dennis R. Burton (La Jolla, California);  Laura Marjorie Walker (San Diego, California);  Pascal Raymond Georges Poignard (San Diego, California);  Wayne Koff (Stony Brook, New York);  Melissa Danielle De Jean De St. Marcel Simek-Lemos (Brooklyn, New York);  Stephen Kaminsky (Bronx, New York)
ABSTRACT The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for neutralization activity against a plurality of HIV-1 species, cloning a memory B cell that exhibits broad neutralization activity; and rescuing a monoclonal antibody from that memory B cell culture. The resultant monoclonal antibodies are characterized by their ability to selectively bind epitopes from the Env proteins in native or monomeric form, as well as to inhibit infection of HIV-1 species from a plurality of clades. Compositions containing human monoclonal anti-HIV antibodies used for prophylaxis, diagnosis and treatment of HIV infection are provided. Methods for generating such antibodies by immunization using epitopes from conserved regions within the variable loops of gp120 are provided. Immunogens for generating anti-HIV1 bNAbs are also provided. Furthermore, methods for vaccination using suitable epitopes are provided.
FILED Wednesday, October 28, 2020
APPL NO 17/082322
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/21 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/1045 (20130101) Original (OR) Class
C07K 16/1063 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584792 Ruiz-Opazo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
INVENTOR(S) Nelson Ruiz-Opazo (Westwood, Massachusetts);  Victoria Herrera (Westwood, Massachusetts)
ABSTRACT Described herein are methods of treating COVID19 from a coronavirus infection, methods of treating a subject having a coronavirus infection, methods of improving a survival rate of a subject having a coronavirus infection, methods of determining prognosis of a subject having a coronavirus infection, methods of preventing or treating organ-dysfunction or multi-organ dysfunction or failure associated with a coronavirus infection, methods of combinational therapy for a subject having a coronavirus infection, methods of reducing microthrombi formation or low flow organ-ischemia associated with a coronavirus infection by administering a DEspR inhibitor.
FILED Thursday, October 14, 2021
APPL NO 17/501050
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39558 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/30 (20130101)
C07K 16/249 (20130101) Original (OR) Class
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584916 Wells et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S) Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S) James M. Wells (Cincinnati, Ohio);  Carey Lane Watson (Cincinnati, Ohio);  Jorge Orlando Munera (Cincinnati, Ohio);  Maxime Mickael Mahe (Cincinnati, Ohio);  Michael A. Helmrath (Cincinnati, Ohio);  Michael J. Workman (Santa Monica, California)
ABSTRACT Disclosed are methods for making a vascularized hollow organ derived from human intestinal organoid (HIOs). The HIOs may be obtained from human embryonic stem cells (ESC's) and/or induced pluripotent stem cells (iPSCs), such that the HIO forms mature intestinal tissue. Also disclosed are methods for making a human intestinal tissue containing a functional enteric nervous system (ENS).
FILED Friday, October 16, 2015
APPL NO 15/515840
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0271 (20130101)
A01K 2227/30 (20130101)
A01K 2227/105 (20130101)
A01K 2267/03 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0679 (20130101) Original (OR) Class
C12N 5/0697 (20130101)
C12N 2501/10 (20130101)
C12N 2501/11 (20130101)
C12N 2501/16 (20130101)
C12N 2501/119 (20130101)
C12N 2501/155 (20130101)
C12N 2501/345 (20130101)
C12N 2501/385 (20130101)
C12N 2501/415 (20130101)
C12N 2501/727 (20130101)
C12N 2502/08 (20130101)
C12N 2502/23 (20130101)
C12N 2503/00 (20130101)
C12N 2506/02 (20130101)
C12N 2506/45 (20130101)
C12N 2513/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5073 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584929 Harkins Kincaid et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CLARET BIOSCIENCE, LLC (Santa Cruz, California)
ASSIGNEE(S) CLARET BIOSCIENCE, LLC (Santa Cruz, California)
INVENTOR(S) Kelly M. Harkins Kincaid (Santa Cruz, California);  Joshua D. Kapp (Santa Cruz, California);  Christopher J. Troll (Santa Cruz, California)
ABSTRACT The technology relates in part to methods and compositions for analyzing nucleic acid. In some aspects, the technology relates to methods and compositions for preparing a nucleic acid library. In some aspects, the technology relates to methods and compositions for analyzing ends of nucleic acid fragments.
FILED Friday, January 11, 2019
APPL NO 16/961113
ART UNIT 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101) Original (OR) Class
C12N 15/1093 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6855 (20130101)
C12Q 1/6855 (20130101)
C12Q 1/6869 (20130101)
C12Q 2525/301 (20130101)
C12Q 2537/143 (20130101)
C12Q 2563/179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584931 Weinberger et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone (San Francisco, California);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The J. David Gladstone Institutes (San Francisco, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Leor S. Weinberger (Oakland, California);  Timothy J. Notton (San Francisco, California)
ABSTRACT Provided are methods and compositions for generating a deletion library, and methods and compositions for generating and identifying a defective interfering particle (DIP). Also provided are transposon cassettes. A subject method can include: inserting a transposon cassette comprising a target sequence for a sequence specific DNA endonuclease into a population of circular target DNAs to generate a population of transposon-inserted circular target DNAs; contacting the population of transposon-inserted circular target DNAs with the sequence specific DNA endonuclease to generate a population of cleaved linear target DNAs; contacting the population of cleaved linear target DNAs with one or more exonucleases to generate a population of deletion DNAs; and circularizing the deletion DNAs to generate a library of circularized deletion DNAs. The population of circular target DNAs can include viral genomic DNA. Also provided are human immunodeficiency virus (HIV) deletion mutants, e.g., interfering, conditionally replicating, HIV deletion mutants, and related constructs.
FILED Thursday, December 14, 2017
APPL NO 16/467233
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/10 (20130101)
C12N 15/66 (20130101)
C12N 15/867 (20130101)
C12N 15/1065 (20130101)
C12N 15/1082 (20130101) Original (OR) Class
C12N 15/1093 (20130101)
C12N 2310/533 (20130101)
C12N 2740/16021 (20130101)
C12N 2740/16062 (20130101)
C12N 2800/80 (20130101)
C12N 2800/90 (20130101)
C12N 2800/107 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6869 (20130101)
C12Q 2563/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584932 Ju et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S) Jingfang Ju (East Setauket, New York);  Andrew Fesler (Sound Beach, New York)
ABSTRACT The present disclosure provides nucleic acid compositions that incorporate one or more halouracil molecules. More specifically, the present disclosure reveals that the replacement of uracil nucleotides within a microRNA nucleotide sequence with a 5-halouracil increases the ability of the micro-RNA to inhibit cancer progression and tumorigenesis. As such, the present disclosure provides various nucleic acid (e.g., microRNA) compositions having 5-halouracil molecules incorporated in their nucleic acid sequences and methods for using the same. The present disclosure further provides pharmaceutical compositions comprising the modified nucleic acid compositions, and methods for treating cancers using the same.
FILED Wednesday, October 31, 2018
APPL NO 16/176137
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/712 (20130101)
A61K 45/06 (20130101)
A61K 48/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1135 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/141 (20130101)
C12N 2310/335 (20130101)
C12N 2310/3533 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584934 Junghans et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Tufts Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Tufts Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Richard P. Junghans (Boston, Massachusetts);  Mumtaz Yaseen (Boston, Massachusetts)
ABSTRACT Provided herein are compositions and methods for improving immune system function. In particular, provided herein are compositions, methods, and uses of YY1 and EZH2 inhibitors for preventing and reversing T-cell exhaustion (e.g., for use in immunotherapy).
FILED Friday, July 14, 2017
APPL NO 16/317446
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/444 (20130101)
A61K 31/496 (20130101)
A61K 31/706 (20130101)
A61K 31/713 (20130101)
A61K 31/713 (20130101)
A61K 31/4439 (20130101)
A61K 31/5377 (20130101)
A61K 31/7088 (20130101)
A61K 31/7088 (20130101)
A61K 31/7105 (20130101)
A61K 31/7105 (20130101)
A61K 35/17 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/00 (20180101)
A61P 35/00 (20180101)
A61P 37/04 (20180101)

Peptides
C07K 14/4702 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1007 (20130101)
C12N 15/1137 (20130101) Original (OR) Class
C12N 2310/14 (20130101)

Enzymes
C12Y 201/01043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584935 Serafini et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) UNIVERSITY OF MIAMI (Miami, Florida)
ASSIGNEE(S) UNIVERSITY OF MIAMI (Miami, Florida);  UNIVERSITY OF MODENA AND REGGIO EMILLA UNIMORE (Modena, Italy)
INVENTOR(S) Paolo Serafini (Miami Shores, Florida);  Dimitri Van Simaeys (Miami Beach, Florida);  Adriana De La Fuente (Miami, Florida);  Alessia Zoso (Miami Shores, Florida);  Silvio Bicciato (Modena, Italy);  Jimmy Caroli (Modena, Italy);  Cristian Taccioli (Legnaro, Italy);  Andrea Grilli (Modena, Italy);  Midhat Abdulreda (Hialeah Gardens, Florida)
ABSTRACT The present disclosure provides materials and methods for the delivery of therapeutic nucleic cells (and imaging agents) to tissues.
FILED Wednesday, May 08, 2019
APPL NO 17/053193
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)
A61P 37/06 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/115 (20130101) Original (OR) Class
C12N 2310/16 (20130101)
C12N 2310/3519 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/507 (20130101)
G01N 33/566 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584949 Georgiou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) AEMASE, INC. (Austin, Texas)
ASSIGNEE(S) AEMASE, INC. (Austin, Texas)
INVENTOR(S) George Georgiou (Austin, Texas);  Everett Stone (Austin, Texas)
ABSTRACT Methods and composition related to the engineering of a novel protein with methionine-γ-lyase enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-γ-lyase (CGL) comprising one or more amino acid substitutions and capable of degrading methionine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with methionine depletion using the disclosed proteins or nucleic acids.
FILED Thursday, November 21, 2019
APPL NO 16/691418
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/88 (20130101)
C12N 9/96 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/10 (20130101)
C12Q 1/527 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2333/988 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584957 Mitra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Lucira Health, Inc. (Emeryville, California)
ASSIGNEE(S) Lucira Health, Inc. (Emeryville, California)
INVENTOR(S) Debkishore Mitra (Berkeley, California);  Ivan Krastev Dimov (Union City, California);  John Robert Waldeisen (Berkeley, California)
ABSTRACT Colorimetry is used to detect amplification reaction products. A sample is contacted with a reaction mix under conditions such that an amplification reaction occurs and produces an amplification reaction product if the sample contains a target nucleic acid template molecule. The reaction mix includes an enzyme for catalyzing the amplification reaction, and at least one halochromic agent. If the target nucleic acid template molecule is present, the amplification reaction changes the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating the presence of the target nucleic acid. If the target nucleic acid template molecule is not present, the amplification reaction does not generate an adequate number of protons to sufficiently change the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating that the amplification reaction product has not been produced.
FILED Friday, June 05, 2020
APPL NO 16/894694
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6844 (20130101) Original (OR) Class
C12Q 1/6846 (20130101)
C12Q 1/6846 (20130101)
C12Q 2527/119 (20130101)
C12Q 2527/125 (20130101)
C12Q 2563/173 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585810 James et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma)
ASSIGNEE(S) OKLAHOMA MEDICAL RESEARCH FOUNDATION (Oklahoma City, Oklahoma)
INVENTOR(S) Judith A. James (Oklahoma City, Oklahoma);  Melissa E. Munroe (Oklahoma City, Oklahoma)
ABSTRACT The present invention involves the identification of biomarkers that are predictive of impeding systemic lupus erythematosus (SLE) disease flare. Methods for treating patients so identified are also provided.
FILED Monday, July 15, 2019
APPL NO 16/512271
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/564 (20130101) Original (OR) Class
G01N 33/6863 (20130101)
G01N 2800/52 (20130101)
G01N 2800/104 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585818 Chiu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Washington through its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) University of Washington through its Center for Commercialization (Seattle, Washington)
INVENTOR(S) Daniel T. Chiu (Seattle, Washington);  Changfeng Wu (Seattle, Washington);  Xuanjun Zhang (Linköping, Sweden);  Jiangbo Yu (Seattle, Washington);  Fangmao Ye (Seattle, Washington)
ABSTRACT The present invention provides, among other aspects, stabilized chromophoric nanoparticles. In certain embodiments, the chromophoric nanoparticles provided herein are rationally functionalized with a pre-determined number of functional groups. In certain embodiments, the stable chromophoric nanoparticles provided herein are modified with a low density of functional groups. In yet other embodiments, the chromophoric nanoparticles provided herein are conjugated to one or more molecules. Also provided herein are methods for making rationally functionalized chromophoric nanoparticles.
FILED Monday, August 10, 2020
APPL NO 16/989491
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/126 (20130101)
C08G 2261/12 (20130101)
C08G 2261/54 (20130101)
C08G 2261/72 (20130101)
C08G 2261/94 (20130101)
C08G 2261/228 (20130101)
C08G 2261/522 (20130101)
C08G 2261/1426 (20130101)
C08G 2261/3142 (20130101)
C08G 2261/3246 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/11 (20130101)
C08J 2327/22 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 11/025 (20130101)
C09K 2211/1425 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/588 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0039 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587361 Radwin et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
National Institute for Occupational Safety and Health (NIOSH)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Robert G. Radwin (Waunakee, Wisconsin);  Runyu L. Greene (Madison, Wisconsin);  Xuan Wang (Madison, Wisconsin);  Yu Hen Hu (Middleton, Wisconsin);  Nicholas Difranco (Naperville, Illinois)
ABSTRACT A monitoring or tracking system may include an input port and a controller in communication with the input port. The input port may receive data from a data recorder. The data recorder is optionally part of the monitoring system and in some cases includes at least part of the controller. The controller may be configured to receive data via the input port and determine values for one or more dimensions of subject performing a task based on the data and determine a location of a hand of the subject performing the task based on the data. Further, the controller may be configured to determine one or both of trunk angle and trunk kinematics based on the received data. The controller may output via the output port assessment information.
FILED Friday, November 06, 2020
APPL NO 17/091903
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 7/62 (20170101)
G06T 7/73 (20170101)
G06T 7/246 (20170101)
G06T 2207/10016 (20130101)
G06T 2207/30196 (20130101)

Image or Video Recognition or Understanding
G06V 40/23 (20220101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587682 Longmire et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Medable Inc. (Palo Alto, California)
ASSIGNEE(S) Medable Inc. (Palo Alto, California)
INVENTOR(S) Michelle Longmire (Palo Alto, California);  Ingrid Oakley-Girvan (Henderson, California);  Nick Moss (Los Alamos, New Mexico)
ABSTRACT A method and system for connecting, capturing, managing and predicting outcomes for an improved care for home based patients by collecting data from caregivers and home-based patients. The method and system implemented as a mobile technology is more efficient and effective method for delivering healthcare that will ease the caregiving burden. Providing resources and information to communicate, capture and deliver by the caregivers (formal and informal), patients and healthcare providers communicate helps integrate essential data and care. Through the use of this mobile technology and associated devices vital information from informal caregivers, which is currently not regularly used in remotely located patients, can be captured and implemented in the decisions and adjustments to patients' care plans. In addition, the technology helps with adherence of patient specific treatment guidelines for home-based patients.
FILED Sunday, March 14, 2021
APPL NO 17/200866
ART UNIT 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/20 (20180101)
G16H 10/65 (20180101)
G16H 50/20 (20180101) Original (OR) Class
G16H 80/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588926 Shi
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Justin Yuan Shi (Wayne, Pennsylvania)
ABSTRACT A system for network-scale parallel computing comprises a set of computer-readable instructions implementing the steps of executing a computational process from at least one client node by communicating via a content addressable service network implemented using the Tuple Space abstraction, data parallel semantics and Unidirectional Virtual Ring architecture, with any number of service computers, networks and storage to deliver lossless, non-stop services. A network-scale distributed storage system, an enhanced Domain Name System (DNS) system, a network-scale database system and a network-scale hybrid transactional analytical processing systems are also described.
FILED Tuesday, November 14, 2017
APPL NO 16/348899
ART UNIT 2447 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 69/14 (20130101)
H04L 69/40 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE49423 Williams
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) NATURE TECHNOLOGY CORPORATION (Lincoln, Nebraska)
ASSIGNEE(S) Nature Technology Corporation (Lincoln, Nebraska)
INVENTOR(S) James A. Williams (Lincoln, Nebraska)
ABSTRACT The present invention relates to the production and use of covalently closed circular (ccc) recombinant plasmids, and more particularly to vector modifications that improve expression of said DNA molecules in the target organism.
FILED Friday, December 04, 2020
APPL NO 17/112918
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/70 (20130101)
C12N 15/85 (20130101)
C12N 15/635 (20130101) Original (OR) Class
C12N 2800/107 (20130101)
C12N 2820/55 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11583578 Dutta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
APPLICANT(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland);  The Government Of The United States, As Represented By The Secretary Of The Army (Fort Detrick, Maryland)
ASSIGNEE(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland);  The Government Of The United States, As Represented By The Secretary Of The Army (Fort Detrick, Maryland)
INVENTOR(S) Sheetij Dutta (Silver Spring, Maryland);  Zoltan Beck (Rockville, Maryland);  Carl Alving (Bethesda, Maryland);  Gary Matyas (Olney, Maryland)
ABSTRACT The invention relates to pharmaceutical compositions comprising at least one antigen and an adjuvant composition, where the adjuvant composition comprises a saponin and a liposome. The liposome of the composition comprises monophosphoryl lipid A (MPLA), cholesterol and a phospholipid that is in a liquid crystalline state at greater than or equal to 23° C., and the concentration of cholesterol to lipid in the liposome is greater than 50% (mol/mol). The antigen in the composition is a soluble Plasmodium falciparum recombinant circumsporozoite protein (rCSP) comprising the amino acid sequence of SEQ ID NO:1, or a P. falciparum rCSP peptide that is at least 95% identical to the amino acid sequence of SEQ ID NO:1.
FILED Friday, April 27, 2018
APPL NO 16/607917
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/015 (20130101) Original (OR) Class
A61K 39/39 (20130101)
A61K 2039/545 (20130101)
A61K 2039/55555 (20130101)
A61K 2039/55572 (20130101)
A61K 2039/55577 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583604 Gressick et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Barron Associates, Inc. (Charlottesville, Virginia)
ASSIGNEE(S) Barron Associates, Inc. (Charlottesville, Virginia)
INVENTOR(S) William T. Gressick (Charlottesville, Virginia);  Brian R. Clark (Charlottesville, Virginia);  Clifford Schultz (Perkins, Oklahoma)
ABSTRACT Embodiments of a controlled odor emission system and device include an odor presentation port tube and an odor tray securely retained against a platform, a valve housing securable to the platform adjacent the tray, a valve secured within the valve housing and an actuator for moving the valve. By controlling movement of the valve, precise amounts of an odor can be dispensed under programmatic control for training animals. Further, a system incorporating a central control unit and a reward dispenser in communication with an odor emission device to facilitate animal training.
FILED Wednesday, April 29, 2020
APPL NO 16/861455
ART UNIT 1799 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 5/0275 (20130101)
A01K 15/02 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 9/032 (20130101)
A61L 9/035 (20130101) Original (OR) Class
A61L 2209/11 (20130101)
A61L 2209/134 (20130101)

Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 13/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584550 Diggans
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Rome, New York)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Rome, New York)
INVENTOR(S) Christopher Tyler Diggans (Fayetteville, New York)
ABSTRACT Various embodiments of the disclosed subject matter provide systems, methods, architectures, mechanisms, apparatus, computer implemented method and/or frameworks configured for tracking Earth orbiting objects and adapting SSN tracking operations to improve tracking accuracy while reducing computational complexity and resource consumption associated with such tracking.
FILED Monday, July 11, 2022
APPL NO 17/861403
ART UNIT 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 3/00 (20130101) Original (OR) Class

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 19/51 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)

Image or Video Recognition or Understanding
G06V 10/76 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584637 Langford et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) William Kai Langford (Cambridge, Massachusetts);  Amanda Ghassaei (Cambridge, Massachusetts);  Neil Gershenfeld (Cambridge, Massachusetts)
ABSTRACT A system of flexural, actuating, and semiconducting elements of part-types necessary to assemble actuated robotic systems. These parts are joined with a common interface, interlocking with neighboring parts to form a regular lattice structure. Primary considerations for the design of the part interfaces include ease of assembly and the ability to transfer mechanical loads and electronic signals to neighboring parts. The parts are designed to be assembled vertically so structures can he built incrementally one part at a time. They can be easily fabricated at a range of length-scales using a variety of two-dimensional manufacturing processes. These processes include, for example, stamping and laminating, which enable high-throughput production. The simple mechanical interfaces between parts also enable disassembly allowing for reconfigurability and reuse. The interlocking nature of these assemblies allows loads to be distributed through many parallel load-paths.
FILED Thursday, August 23, 2018
APPL NO 16/109947
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0021 (20130101)
B81B 7/0003 (20130101) Original (OR) Class
B81B 2201/13 (20130101)
B81B 2207/07 (20130101)

Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00007 (20130101)

Dynamo-electric Machines
H02K 41/0354 (20130101)

Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils
H02P 7/025 (20160201)
H02P 25/034 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584718 Shapiro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) David J. Shapiro (Urbana, Illinois);  Paul J. Hergenrother (Champaign, Illinois);  Matthew W. Boudreau (Urbana, Illinois)
ABSTRACT A set of small molecules ERα biomodulators that kill therapy-resistant ERα positive breast, ovarian, and endometrial cancer cells. These small molecules have increased therapeutic potential because of an increased ability to kill therapy-resistant breast cancer cells compared to BHPI and other conventional therapies (endocrine therapies, tamoxifen and fulvestrant/ICI). The new compounds do not only inhibit proliferation of the cancer cells but actually kills them, which prevents reactivation of tumors years later.
FILED Thursday, May 13, 2021
APPL NO 17/319447
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0053 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 209/34 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584826 Martin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brett D. Martin (Washington, District of Columbia);  Jawad Naciri (Arlington, Virginia);  Banahalli R. Ratna (Alexandria, Virginia)
ABSTRACT An interpenetrating network (IPN) polymer membrane material includes a soft polyurethane interspersed with a crosslinked conducting polymer. The material can be reversibly “switched” between its oxidized and reduced states by the application of a small voltage, ˜1 to 4 volts, thus modulating its diffusivity.
FILED Thursday, March 24, 2022
APPL NO 17/703729
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/126 (20130101) Original (OR) Class
C08G 81/00 (20130101)
C08G 2261/70 (20130101)
C08G 2261/122 (20130101)
C08G 2261/126 (20130101)
C08G 2261/514 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/127 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584931 Weinberger et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone (San Francisco, California);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The J. David Gladstone Institutes (San Francisco, California);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Leor S. Weinberger (Oakland, California);  Timothy J. Notton (San Francisco, California)
ABSTRACT Provided are methods and compositions for generating a deletion library, and methods and compositions for generating and identifying a defective interfering particle (DIP). Also provided are transposon cassettes. A subject method can include: inserting a transposon cassette comprising a target sequence for a sequence specific DNA endonuclease into a population of circular target DNAs to generate a population of transposon-inserted circular target DNAs; contacting the population of transposon-inserted circular target DNAs with the sequence specific DNA endonuclease to generate a population of cleaved linear target DNAs; contacting the population of cleaved linear target DNAs with one or more exonucleases to generate a population of deletion DNAs; and circularizing the deletion DNAs to generate a library of circularized deletion DNAs. The population of circular target DNAs can include viral genomic DNA. Also provided are human immunodeficiency virus (HIV) deletion mutants, e.g., interfering, conditionally replicating, HIV deletion mutants, and related constructs.
FILED Thursday, December 14, 2017
APPL NO 16/467233
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/10 (20130101)
C12N 15/66 (20130101)
C12N 15/867 (20130101)
C12N 15/1065 (20130101)
C12N 15/1082 (20130101) Original (OR) Class
C12N 15/1093 (20130101)
C12N 2310/533 (20130101)
C12N 2740/16021 (20130101)
C12N 2740/16062 (20130101)
C12N 2800/80 (20130101)
C12N 2800/90 (20130101)
C12N 2800/107 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6869 (20130101)
C12Q 2563/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584934 Junghans et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Tufts Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Tufts Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Richard P. Junghans (Boston, Massachusetts);  Mumtaz Yaseen (Boston, Massachusetts)
ABSTRACT Provided herein are compositions and methods for improving immune system function. In particular, provided herein are compositions, methods, and uses of YY1 and EZH2 inhibitors for preventing and reversing T-cell exhaustion (e.g., for use in immunotherapy).
FILED Friday, July 14, 2017
APPL NO 16/317446
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/444 (20130101)
A61K 31/496 (20130101)
A61K 31/706 (20130101)
A61K 31/713 (20130101)
A61K 31/713 (20130101)
A61K 31/4439 (20130101)
A61K 31/5377 (20130101)
A61K 31/7088 (20130101)
A61K 31/7088 (20130101)
A61K 31/7105 (20130101)
A61K 31/7105 (20130101)
A61K 35/17 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/00 (20180101)
A61P 35/00 (20180101)
A61P 37/04 (20180101)

Peptides
C07K 14/4702 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1007 (20130101)
C12N 15/1137 (20130101) Original (OR) Class
C12N 2310/14 (20130101)

Enzymes
C12Y 201/01043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585221 Buchanan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) William Gregory Buchanan (King George, Virginia);  Eric A. Wheater (King George, Virginia);  Vincent J. Vendetti (King George, Virginia)
ASSIGNEE(S) United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) William Gregory Buchanan (King George, Virginia);  Eric A. Wheater (King George, Virginia);  Vincent J. Vendetti (King George, Virginia)
ABSTRACT A rotary engine is provided for providing torque. The engine includes a housing, a stator, a crank shaft, a rotor and a pair of vanes. The housing has an inner wall with an elliptical profile with major and minor axes. The stator has an outer wall and a double ellipsoid profile corresponding to the major and minor axes. The crank shaft is disposed at a junction of the major and minor axes, rotating about a spin axis orthogonal to the profiles. The rotor has an annular circular profile disposed between the inner and outer walls. The rotor turns on the crank shaft. The vanes radially slide within the rotor as the crank shaft rotates and as the vanes turn within the inner and outer walls.
FILED Friday, April 03, 2020
APPL NO 16/840186
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary-piston or Oscillating-piston Machines or Engines
F01C 1/22 (20130101)
F01C 1/344 (20130101) Original (OR) Class
F01C 1/3568 (20130101)

Internal-combustion Piston Engines; Combustion Engines in General
F02B 53/00 (20130101)
F02B 53/04 (20130101)
F02B 53/06 (20130101)
F02B 55/00 (20130101)
F02B 55/02 (20130101)
F02B 55/08 (20130101)
F02B 55/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585227 Slipper et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Michael E. Slipper (Ridley Park, Pennsylvania);  Tristan M. Wolfe (Philadelphia, Pennsylvania);  Kyle J. Verrinder (West Chester, Pennsylvania)
ABSTRACT A flow control device for constraining fluid flow between axial flow turbomachines in series has a flow constrainer which constrains the fluid flow downstream of the first turbomachine in the series to the blades region of the second turbomachine, preventing fluid flow from impacting the hub or nosecone of the second turbomachine and providing more uniform fluid flow to the second turbomachine. The flow control device includes connective elements for positioning between the downstream region of the first turbomachine and the upstream region of the second turbomachine. The device may be equipped with stator vanes having a variety of optional configurations to further improve the uniformity of the fluid flow load on the second turbomachine.
FILED Thursday, October 31, 2019
APPL NO 16/670426
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 9/041 (20130101) Original (OR) Class

Non-positive-displacement Pumps
F04D 23/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585475 Marks
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Galen L. Marks (Oxnard, California)
ABSTRACT A dual cam lever hose clamp may comprise: first and second cam lever clamps and upper and lower clamp halves. The cam lever clamps may move between a retaining position and release position. The upper and lower clamp halves may form a collar when opposing ends of the clamp halves fasten together via the cam lever clamps. The first cam lever clamp may comprise a first linkage pivotally coupled to a first end of the lower clamp half and a first cam lever pivotally coupled to the first linkage. The second cam lever clamp may comprise a second linkage pivotally coupled to a second end of the lower clamp half and a second cam lever pivotally coupled to the second linkage. The first and second cam lever clamps may comprise cam levers that cammingly engage cam locking surfaces on the upper clamp half to fasten and tighten the collar.
FILED Tuesday, June 09, 2020
APPL NO 16/896365
ART UNIT 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 33/10 (20130101)
F16L 33/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585639 Pinsky et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James Gregory Pinsky (Remington, Virginia);  Philip J. Dudt (North Bethesda, Maryland);  Devin P. Murphy (Sterling, Virginia)
ABSTRACT According to exemplary inventive practice, a personal armor system includes a textile-based layer not exceeding ½-half-inch thickness, and an elastomeric coating not exceeding ⅛-inch thickness. The textile-based layer includes a fiber reinforcement and a resin binder. The combined areal density of the textile-based layer and the elastomeric coating does not exceed 2.5 psf. According to a first mode of inventive practice, the elastomeric coating is essentially a strain-rate-sensitivity-hardening elastomer, and the areal density of the textile-based layer does not exceed 2.3 psf. According to a second mode of inventive practice, the elastomeric coating is essentially a microparticle-filled strain-rate-sensitivity-hardening elastomeric matrix material, and the areal density of the textile-based layer does not exceed 1.7 psf. The microparticles (e.g., spherical glass microparticles) do not exceed, by weight, 30 percent of the strain-rate-sensitivity-hardening elastomeric matrix material. The textile-based layer affords ballistic protection; the elastomeric coating affords protection against sharp/pointed objects.
FILED Thursday, August 01, 2019
APPL NO 16/529432
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 31/24 (20190201)
A41D 31/245 (20190201)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 9/045 (20130101)
B32B 9/047 (20130101)
B32B 2307/50 (20130101)
B32B 2307/584 (20130101)
B32B 2571/00 (20130101)
B32B 2571/02 (20130101)

Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 1/02 (20130101)
F41H 5/0471 (20130101)
F41H 5/0478 (20130101) Original (OR) Class
F41H 5/0485 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585660 Opperman et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Armaments Center (CCDC AC)
Office of the Secretary of Defense (OSD)
APPLICANT(S) Orbital Research Inc. (Cleveland, Ohio)
ASSIGNEE(S) Orbital Research Inc. (Cleveland, Ohio)
INVENTOR(S) Anthony Opperman (Wickliffe, Ohio);  Frederick J. Lisy (Euclid, Ohio);  Edward J. Rapp (Cleveland Heights, Ohio);  Angela M. Lisy (Euclid, Ohio);  Scott Suren (Brunswick, Ohio);  Douglas E. Russell (Canal Fulton, Ohio)
ABSTRACT Inertial measurement units (IMUs) and methods with adaptations to eliminate or minimize sensor error, offset, or bias shift. More particularly, such IMUs and methods for gun-fired projectiles and particularly adapted to accurately measure forces and to prevent or minimize the error, offset, or bias shift associated with events exhibiting high g shock, and/or high levels of vibration, and/or rotation. Even more particularly, such IMUs and methods utilizing novel IMU packaging adapted to prevent or minimize sensor error, offset, or bias shift, and recalibration adaptations and methods adapted to correct or reset the error, offset, or bias shift from such an event. Ultimately relates to IMUs that are adapted to provide accurate measurements prior to, during and after such event, and to provide continuous accurate measurements during flight of gun-fired projectiles.
FILED Friday, August 14, 2020
APPL NO 16/993336
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 15/01 (20130101)
F42B 30/10 (20130101)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/16 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585798 Soliz
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
APPLICANT(S) U.S. Army Combat Capabilities Development Command, Chemical Biological Center (Apg, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Jennifer R Soliz (Baltimore, Maryland)
ABSTRACT The invention is directed towards dielectric materials, BaTiO3, BaZrO3, and/or BaTi1-xZrxO3, such that 0≤x≤1, for detecting, sensing, filtering, reacting, or absorbing toxic chemicals, such as chemical warfare agents (“CWAs”) and their structural analogs, toxic industrial chemicals and narcotics, wherein the dielectric material is incorporated into a sensor for detecting, sensing, filtering, reacting, or absorbing the toxic chemicals.
FILED Thursday, February 07, 2019
APPL NO 16/269988
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 23/006 (20130101)
C01G 25/02 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/34 (20130101)
C01P 2002/72 (20130101)
C01P 2002/82 (20130101)
C01P 2002/88 (20130101)
C01P 2006/40 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/0057 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585870 Kim et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Laura Kim (Belmont, Massachusetts);  Hyeongrak Choi (Cambridge, Massachusetts);  Matthew Edwin Trusheim (Cambridge, Massachusetts);  Dirk Robert Englund (Brookline, Massachusetts)
ABSTRACT Nitrogen vacancy (NV) centers in diamond combine exceptional sensitivity with nanoscale spatial resolution by optically detected magnetic resonance (ODMR). Infrared (IR)-absorption-based readout of the NV singlet state transition can increase ODMR contrast and collection efficiency. Here, a resonant diamond metallodielectric metasurface amplifies IR absorption by concentrating the optical field near the diamond surface. This plasmonic quantum sensing metasurface (PQSM) supports plasmonic surface lattice resonances and balances field localization and sensing volume to optimize spin readout sensitivity. Combined electromagnetic and rate-equation modeling suggests a near-spin-projection-noise-limited sensitivity below 1 nT Hz−1/2 per μm2 of sensing area using numbers for contemporary NV diamond samples and fabrication techniques. The PQSM enables microscopic ODMR sensing with IR readout near the spin-projection-noise-limited sensitivity, making it appealing for imaging through scattering tissues and spatially resolved chemical NMR detection.
FILED Thursday, July 15, 2021
APPL NO 17/376234
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 29/0885 (20130101)
G01R 33/032 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585986 Corl et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Wavefront Research, Inc. (Northampton, Pennsylvania)
ASSIGNEE(S) Wavefront Research, Inc. (Northhampton, Pennsylvania)
INVENTOR(S) Jonas D. Corl (Bethleham, Pennsylvania);  David M. Vincentsen (Bethlehem, Pennsylvania);  Thomas A. Mitchell (Nazareth, Pennsylvania);  Michelle M. Stone (Hellertown, Pennsylvania);  Thomas W. Stone (Hellertown, Pennsylvania);  James W. Guelzow (Victor, New York)
ABSTRACT Optical connectors that substantially preserve alignment and are easy to manufacture. The alignment system using the optical connectors disclosed herein include a first housing, a second housing and an alignment component, the said alignment component configured to provide optical alignment between the optical components.
FILED Tuesday, January 14, 2020
APPL NO 16/742468
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/262 (20130101)
G02B 6/366 (20130101) Original (OR) Class
G02B 6/3803 (20130101)
G02B 6/3874 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586152 Trusheim et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The USA as Represented by the Secy. of the Army (Washington, District of Columbia)
INVENTOR(S) Matthew Edwin Trusheim (Cambridge, Massachusetts);  Kurt Jacobs (Columbia, Maryland);  Jonathan Hoffman (Greenbelt, Maryland);  Donald Fahey (Washington, District of Columbia);  Dirk Robert Englund (Brookline, Massachusetts)
ABSTRACT An ensemble of spin defect centers or other atom-like quantum systems in a solid-state host can be used as a compact alternative for an atomic clock thanks to an architecture that overcomes magnetic and temperature-induced systematics. A polariton-stabilized solid-state spin clock hybridizes a microwave resonator with a magnetic-field-insensitive spin transition within the ground state of a spin defect center (e.g., a nitrogen vacancy center in diamond). Detailed numerical and analytical modeling of this polariton-stabilized solid-state spin clock indicates a potential fractional frequency instability below 10−13 over a 1-second measurement time, assuming present-day experimental parameters. This stability is a significant improvement over the state-of-the-art in miniaturized atomic vapor clocks.
FILED Monday, October 18, 2021
APPL NO 17/504238
ART UNIT 2849 — Optics
CURRENT CPC
Time-interval Measuring
G04F 5/14 (20130101) Original (OR) Class

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586200 Fadaie et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois);  HRL Laboratories LLC (Malibu, California)
INVENTOR(S) Joshua G. Fadaie (Saint Louis, Missouri);  Richard Hanes (Ballwin, Missouri);  Chun Kit Chung (Saint Louis, Missouri);  Sean Soleyman (Calabasas, California);  Deepak Khosla (Camarillo, California)
ABSTRACT A method includes receiving, by machine-learning logic, observations indicative of a states associated with a first and second group of vehicles arranged within an engagement zone during a first interval of an engagement between the first and the second group of vehicles. The machine-learning logic determines actions based on the observations that, when taken simultaneously by the first group of vehicles during the first interval, are predicted by the machine-learning logic to result in removal of one or more vehicles of the second group of vehicles from the engagement zone during the engagement. The machine-learning logic is trained using a reinforcement learning technique and on simulated engagements between the first and second group of vehicles to determine sequences of actions that are predicted to result in one or more vehicles of the second group being removed from the engagement zone. The machine-learning logic communicates the plurality of actions to the first group of vehicles.
FILED Monday, June 22, 2020
APPL NO 16/908199
ART UNIT 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Systems for Controlling or Regulating Non-electric Variables
G05D 1/0022 (20130101)
G05D 1/0027 (20130101) Original (OR) Class
G05D 1/106 (20190501)

Electric Digital Data Processing
G06F 9/3818 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6256 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586439 Brewer
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Micron Technology, Inc. (Boise, Idaho)
ASSIGNEE(S) Micron Technology, Inc. (Boise, Idaho)
INVENTOR(S) Tony Brewer (Plano, Texas)
ABSTRACT Disclosed in some examples are systems, methods, devices, and machine-readable mediums to detect and terminate programmable atomic transactions that are stuck in an infinite loop. In order to detect and terminate these transactions, the programmable atomic unit may use an instruction counter that increments each time an instruction is executed during execution of a programmable atomic transaction. If the instruction counter meets or exceeds a threshold instruction execution limit without reaching the termination instruction, the programmable atomic transaction may be terminated, all resources used (e.g., memory locks) may be freed, and a response may be sent to a calling processor.
FILED Tuesday, October 20, 2020
APPL NO 17/074834
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3004 (20130101) Original (OR) Class
G06F 12/0815 (20130101)
G06F 12/0875 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586478 Vega et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Augusto Vega (Mount Vernon, New York);  Alper Buyuktosunoglu (White Plains, New York);  Pradip Bose (Yorktown Heights, New York);  Vaidyanathan Srinivasan (Bangalore, India);  Ranjal Gautham Shenoy (Bangalore, India)
ABSTRACT Systems, computer-implemented methods and/or computer program products that facilitate management of resources are provided. In one embodiment, a computer-implemented method comprises: employing, by a system operatively coupled to a processor, at least one model to predict respective token needs by a set of processing elements during execution of a workload; and exchanging, by the system, one or more tokens between a subset of the processing elements as a function of the predicted token needs.
FILED Tuesday, August 21, 2018
APPL NO 16/107201
ART UNIT 2196 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/5044 (20130101)
G06F 9/5061 (20130101)
G06F 9/5083 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 5/043 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586570 Noa
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Eagle Technology, LLC (Melbourne, Florida)
ASSIGNEE(S) EAGLE TECHNOLOGY, LLC (Melbourne, Florida)
INVENTOR(S) David Noa (North Amityville, New York)
ABSTRACT A carriage system on an aircraft determines the type of each store attached to the carriage system. The carriage system detects stores attached to the carriage system and determines whether a first interlock signal formatted according to a first interface format is present for each store. If the first interlock signal is present, then the dual mode carriage system determines that a store interface for the store is the first interface format. If the first interlock signal is not present for the store, the carriage system determines whether a second interlock signal formatted according to a second interface format is present on a predetermined set of connection pins of the first interface format. If the second interlock signal is present, then the carriage system determines that the store interface for the store is the second interface format. The carriage system reports the store interface of each store to the aircraft.
FILED Friday, January 25, 2019
APPL NO 16/257764
ART UNIT 2186 — Computer Architecture and I/O
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 7/00 (20130101)

Electric Digital Data Processing
G06F 13/16 (20130101)
G06F 13/102 (20130101)
G06F 13/387 (20130101) Original (OR) Class
G06F 13/4068 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586680 Agrawal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Dakshi Agrawal (Monsey, New York);  Raghu K. Ganti (Elmsford, New York);  Mudhakar Srivatsa (White Plains, New York);  Petros Zerfos (New York, New York)
ABSTRACT A system and method are provided for discovering k-nearest-neighbors to a given point within a certain distance d. The method includes constructing an index of geometries using geohashes of geometries as an indexing key to obtain an indexed set of geometries, and calculating a geohash representation of the given point with a resolution equal to a magnitude value of d. The method includes searching for a closest-prefix geometry from the indexed set using the geohash representation of the given point, and identifying geometries from the indexed set having a same prefix as the closest-prefix geometry. The method further includes calculating distances between the given point and the geometries identified from the indexed set having the same prefix as the closest-prefix geometry, and determining k geometries with respective shortest distances less than d from the geometries identified from the indexed set having the same prefix as the closest-prefix geometry.
FILED Monday, March 31, 2014
APPL NO 14/230676
ART UNIT 2162 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/29 (20190101)
G06F 16/9014 (20190101)
G06F 16/90344 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586795 Markowski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Blerta Bajramaj Markowski (Springfield, Virginia);  Brian Carl Hicks (Alexandria, Virginia);  David Bonanno (Fairfax Station, Virginia);  Freddie Santiago (Fort Washington, Maryland)
ABSTRACT Systems and methods are provided for a turnkey modular printed circuit board enclosure that is generated using a template generator. The template generator accepts a user input comprising an enclosure parameter, based on which a manufacturing file may be generated. The manufacturing file may be provided to a fabricator for fabricating the enclosure or the manufacturing file may be modified in a printed circuit board design environment to incorporate a printed circuit board into the enclosure. The printed circuit board may be a separate printed circuit board that is inserted into the enclosure or it may be embedded in a face of the enclosure.
FILED Friday, January 15, 2021
APPL NO 17/150622
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Electric Digital Data Processing
G06F 30/392 (20200101) Original (OR) Class
G06F 30/394 (20200101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 3/0005 (20130101)
H05K 5/0256 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586864 Kachman et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Tal Kachman (Haifa, Israel);  Lior Horesh (North Salem, New York);  Kenneth Lee Clarkson (Madison, New Jersey);  Mark S. Squillante (Greenwich, Connecticut)
ABSTRACT Techniques regarding topological classification of complex datasets are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise a quantum computing component that can encode eigenvalues of a Laplacian matrix into a phase on a quantum state of a quantum circuit. The computer executable components can also comprise a classical computing component that infers a Betti number using a Bayesian learning algorithm by measuring an ancilla state of the quantum circuit.
FILED Friday, February 15, 2019
APPL NO 16/276719
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Electric Digital Data Processing
G06F 17/16 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6278 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 7/005 (20130101)
G06N 10/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586875 Thornton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jason R. Thornton (Chelmsford, Massachusetts);  Luke Skelly (Groton, Massachusetts);  Michael Chan (Bedford, Massachusetts);  Ronald Duarte (Warwick, Rhode Island);  Daniel Scarafoni (Cambridge, Massachusetts)
ABSTRACT Systems and methods are provided for selecting an optimized data model architecture subject to resource constraints. One or more resource constraints for target deployment are identified, and random model architectures are generated from a set of model architecture production rules subject to the one or more resource constraints. Each random model architecture is defined by randomly chosen values for one or more meta parameters and one or more layer parameters. One or more of the random model architectures are adaptively refined to improve performance relative to a metric, and the refined model architecture with the best performance relative to the metric is selected.
FILED Wednesday, November 21, 2018
APPL NO 16/198321
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101) Original (OR) Class
G06N 3/084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586884 Yang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) University of Massachusetts (Amherst, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Jianhua Yang (Hadley, Massachusetts);  Qiangfei Xia (Amherst, Massachusetts);  Mark McLean (Severna Park, Maryland);  Qing Wu (Manilus, New York)
ABSTRACT A diffusive memristor device and an electronic device for emulating a biological neuron is disclosed. The diffusive memristor device includes a bottom electrode, a top electrode formed opposite the bottom electrode, and a dielectric layer disposed between the top electrode and the bottom electrode. The dielectric layer comprises an oxide doped with a metal.
FILED Friday, February 08, 2019
APPL NO 16/270848
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/061 (20130101)
G06N 3/063 (20130101) Original (OR) Class
G06N 3/0454 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586961 Binder
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
APPLICANT(S) RAYTHEON COMPANY (Waltham, Massachusetts)
ASSIGNEE(S) RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S) Michael Karl Binder (Tucson, Arizona)
ABSTRACT A system and method for selecting one sensor from among a plurality of sensors. For each of the plurality of sensors, a conditional probability of the sensor correctly identifying the target from among a plurality of objects detected by the sensor, given an association event, is calculated, and multiplied by a reward function for the sensor. The sensor for which this product is greatest is selected.
FILED Thursday, August 16, 2018
APPL NO 16/104097
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/13 (20130101)

Computer Systems Based on Specific Computational Models
G06N 7/005 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587311 Shaddix et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Slingshot Aerospace, Inc. (Austin, Texas)
ASSIGNEE(S) Slingshot Aerospace, Inc. (Austin, Texas)
INVENTOR(S) Jeffrey Hale Shaddix (Fort Collins, Colorado);  Austin Tyler Hariri (Fort Collins, Colorado);  Jeffrey Michael Aristoff (Fort Collins, Colorado)
ABSTRACT In some embodiments, space objects may be detected within shortwave infrared (SWIR) images captured during the daytime. Some embodiments include obtaining a stacked image by stacking shortwave infrared (SWIR) images. A spatial background-difference image may be generated based on the stacked image, and a matched-filter image may be obtained based on the spatial background-difference image. A binary mask may be generated based on the matched-filter image. The binary mask may include a plurality of bits each of which including a first value or a second value based on whether a signal-to-noise ratio (SNR) associated with that bit satisfies a threshold condition. Output data may be generated based on the spatial background-difference image and the binary mask, where the output data provides observations on detected space objects in orbit.
FILED Monday, July 27, 2020
APPL NO 16/940346
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 16/909 (20190101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/623 (20130101)
G06K 9/6218 (20130101)

Image or Video Recognition or Understanding
G06V 10/7515 (20220101)
G06V 20/13 (20220101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587464 Tessier et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Paul Tessier (Lynnfield, Massachusetts);  Olin Lathrop (Boston, Massachusetts);  James Gordon (Boston, Massachusetts);  Mark Ottensmeyer (Cambridge, Massachusetts);  Aaron Panone (Somerville, Massachusetts);  Michael Wollowitz (Chatham, New York)
ABSTRACT A system and method for providing a medical simulation device that utilizes open software platforms and provides functionality in both software and hardware modules is disclosed. The medical simulation system facilitates plug and play operation with installed hardware and software modules that are automatically recognized by the system for compatibility and the system configures itself according to identification information of the hardware module.
FILED Tuesday, October 22, 2019
APPL NO 16/660450
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 23/288 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588043 Ontalus et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) GLOBALFOUNDRIES U.S. Inc. (Santa Clara, California)
ASSIGNEE(S) GlobalFoundries U.S. Inc. (Malta, New York)
INVENTOR(S) Viorel C. Ontalus (Hartford, Connecticut);  Judson R. Holt (Ballston Lake, New York)
ABSTRACT Aspects of the disclosure provide a bipolar transistor structure with an elevated extrinsic base, and related methods to form the same. A bipolar transistor according to the disclosure may include a collector on a substrate, and a base film on the collector. The base film includes a crystalline region on the collector and a non-crystalline region adjacent the crystalline region. An emitter is on a first portion of the crystalline region of the base film. An elevated extrinsic base is on a second portion of the crystalline region of the base film, and adjacent the emitter.
FILED Wednesday, April 14, 2021
APPL NO 17/229950
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/161 (20130101)
H01L 29/167 (20130101)
H01L 29/0649 (20130101)
H01L 29/1004 (20130101)
H01L 29/7325 (20130101) Original (OR) Class
H01L 29/66234 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588176 Lin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Bioenno Tech LLC (Santa Ana, California)
ASSIGNEE(S) Bioenno Tech LLC (Santa Ana, California)
INVENTOR(S) Zhigang Lin (Santa Ana, California);  Chunhu Tan (Santa Ana, California);  Tianyu Meng (Santa Ana, California)
ABSTRACT Electrolyte-infiltrated composite electrode includes an electrolyte component consisting of a polymer matrix with ceramic nanoparticles embedded in the matrix to form a networking structure of electrolyte. Suitable ceramic nanoparticles have the basic formula Li7La3Zr2O12 (LLZO) and its derivatives such as AlxLi7-xLa3Zr2-y-zTayNbzO12 where x ranges from 0 to 0.85, y ranges from 0 to 0.50 and z ranges from 0 to 0.75, wherein at least one of x, y and z is not equal to 0. The networking structure of the electrolyte establishes an effective lithium-ion transport pathway in the electrode and strengthens the contact between electrode layer and solid-state electrolyte resulting in higher lithium-ion electrochemical cell's cycling stability and longer battery life. Sold-state electrolytes incorporating the ceramic particles demonstrate improved performance. Large dimensional electrolyte-infiltrated composite electrode sheets can be used in all solid-state lithium electrochemical pouch cells which can be assembled into battery packs.
FILED Monday, January 04, 2021
APPL NO 17/140690
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/622 (20130101)
H01M 4/625 (20130101)
H01M 10/0525 (20130101)
H01M 10/0562 (20130101) Original (OR) Class
H01M 2004/021 (20130101)
H01M 2300/0071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588196 Evans et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) Aspen Aerogels, Inc. (Northborough, Massachusetts)
ASSIGNEE(S) Aspen Aerogels, Inc. (Northborough, Massachusetts)
INVENTOR(S) Owen Richard Evans (Chelmsford, Massachusetts);  Nicholas Anthony Zafiropoulos (Wayland, Massachusetts);  Shannon Olga White (Bolton, Massachusetts);  Wenting Dong (Marlborough, Massachusetts);  Wendell E. Rhine (Belmont, Massachusetts)
ABSTRACT The present invention provides a fiber-reinforced aerogel material which can be used as insulation in thermal battery applications. The fiber-reinforced aerogel material is highly durable, flexible, and has a thermal performance that exceeds the insulation materials currently used in thermal battery applications. The fiber-reinforced aerogel insulation material can be as thin as 1 mm less, and can have a thickness variation as low as 2% or less. Also provided is a method for improving the performance of a thermal battery by incorporating a reinforced aerogel material into the thermal battery. Further provided is a casting method for producing thin fiber-reinforced aerogel materials.
FILED Friday, May 06, 2022
APPL NO 17/738852
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/0091 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 6/36 (20130101)
H01M 6/5072 (20130101)
H01M 50/116 (20210101)
H01M 50/138 (20210101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588221 Ray
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Space and Missile Defense Command (SMDC)
APPLICANT(S) U.S. Army Space and Missile Defense Command (Huntsville, Alabama)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Mark E. Ray (Madison, Alabama)
ABSTRACT A dual-use spring attached to a small satellite that performs two common functions for small satellites including operating as a communications antenna for the small satellite, which eliminates the need for a separate antenna deployment step, and ejecting the small satellite from a modified deployment container mounted on a launch vehicle. The deployment container is modified by removing a conventional deployment spring and pusher plate, which increases available container space.
FILED Wednesday, December 08, 2021
APPL NO 17/545088
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/36 (20130101)
H01Q 1/084 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588292 Reeves-Hall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Peter Reeves-Hall (Northbridge, Massachusetts);  Juan C. Montoya (Belmont, Massachusetts);  Dale H. Martz (Medford, Massachusetts)
ABSTRACT A photonic lantern couples light from several fibers or fiber cores into one or more fibers or fiber cores. Photonic lanterns are often used to combine several lower-power beams into a single higher-power beam. They can also be used to couple light from multi-core fibers into single-mode, multi-mode, or other multi-core fibers. By modulating the phases of the input beams, the light can be switched from output to output—for example, between output cores of a multi-core output fiber. If desired, the beams can also be amplified using an active fiber in or coupled to the photonic lantern. A first photonic lantern couples signal light and pump light into the core and cladding, respectively, of an active multi-mode or multi-core fiber. And the active multi-mode or multi-core fiber couples amplified signal light into output fiber(s) via a second photonic lantern.
FILED Thursday, September 05, 2019
APPL NO 16/561580
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/2813 (20130101)
G02B 6/2843 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/091 (20130101)
H01S 3/1305 (20130101)
H01S 3/1312 (20130101)
H01S 3/06787 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588456 Lagally et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin);  THE REGENTS OF THE UNIVERSITY OF NEW MEXICO (Albuquerque, New Mexico)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Max G. Lagally (Madison, Wisconsin);  Matthew McLean Dwyer (Madison, Wisconsin);  Daniel Warren van der Weide (Madison, Wisconsin);  Abhishek Bhat (Fremont, California);  Francesca Cavallo (Albuquerque, New Mexico);  Divya Jyoti Prakash (Albuquerque, New Mexico)
ABSTRACT Traveling-wave tube amplifiers and methods for making slow-wave structures for the amplifiers are provided. The SWSs include helical conductors that are self-assembled via the release of stressed electrically conductive strips from a sacrificial material. The helical conductors can be electroplated post-self-assembly to fortify the helix, reduce losses, and tailor the dimensions and operating parameters of the helix.
FILED Monday, May 25, 2020
APPL NO 16/882591
ART UNIT 2875 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 23/26 (20130101)
H01J 23/165 (20130101)
H01J 25/36 (20130101)

Amplifiers
H03F 3/58 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588516 Dafesh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Philip A. Dafesh (Manhattan Beach, California);  Phillip Brian Hess (Venice, California)
ABSTRACT Under one aspect, a method is provided for processing a received signal, the received signal including a desired signal and an interference signal that spectrally overlaps the desired signal. The method can include obtaining an amplitude of the received signal. The method also can include obtaining an average amplitude of the received signal based on at least one prior amplitude of the received signal. The method also can include subtracting the amplitude from the average amplitude to obtain an amplitude residual. The method also can include, based upon an absolute value of the amplitude residual being less than or equal to a first threshold, inputting the received signal into an interference suppression algorithm so as to generate a first output including the desired signal with reduced contribution from the interference signal.
FILED Tuesday, August 10, 2021
APPL NO 17/398992
ART UNIT 2637 — Optical Communications
CURRENT CPC
Transmission
H04B 1/719 (20130101)
H04B 1/1027 (20130101)
H04B 1/1036 (20130101)
H04B 1/7107 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588556 Conrad et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Stephen Conrad (Bedford, Massachusetts);  Adam Alexander Libson (Newton, Massachusetts);  Andrew Benedick (Stow, Massachusetts);  Dale H. Martz (Somerville, Massachusetts);  Jonathan Twichell (Acton, Massachusetts);  Eli Doris (Somerville, Massachusetts)
ABSTRACT A High Bandwidth Individual Channel Control via Optical Reference Interferometry (HICCORI) system actively controls the phase and/or polarization of the optical emission of each element in a tiled optical array. It can also actively align any high-frequency broadening waveform applied to the array beams for spectral broadening or data transmission. By maintaining consistent polarization and manipulating the phase relationships of the beams emitted by the array elements, the HICCORI system can manipulate the spatial pattern of constructive and destructive interference formed as the individual emissions coherently combine. Active feedback control allows the desired phase, polarization, and/or spectral broadening alignment to be maintained in the presence of external disturbances.
FILED Tuesday, June 01, 2021
APPL NO 17/335321
ART UNIT 2636 — Optical Communications
CURRENT CPC
Transmission
H04B 10/548 (20130101)
H04B 10/675 (20130101)
H04B 10/50577 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588745 Pospesel
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Micron Technology, Inc. (Boise, Idaho)
ASSIGNEE(S) Micron Technology, Inc. (Boise, Idaho)
INVENTOR(S) Kirk D. Pospesel (Clinton Corners, New York)
ABSTRACT A device allocates buffer space for storing data received from another device. The other device has a credit balance corresponding to the amount of buffer space. A sending device reduces its number of credits by a cost of a packet and sends the packet. To ensure that the buffer does not overflow, the sending device spends a credit for each entry in the buffer that could be consumed by the sent data packet. When received data is added to the buffer without consuming a new entry, a response packet that returns a credit is sent to the sending device before the data is read from the buffer. Thus, the sending device is enabled to continue sending data without waiting for the buffer to be read, enabling the communication between the two devices to make more efficient use of the buffer.
FILED Monday, August 31, 2020
APPL NO 17/007516
ART UNIT 2464 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 47/39 (20130101) Original (OR) Class
H04L 47/527 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11589360 Kong et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Justin S. Kong (Clarksville, Maryland);  Fikadu T. Dagefu (Silver Spring, Maryland);  Brian M. Sadler (Laurel, Maryland)
ABSTRACT A system and method for distributed wireless communications comprising a first group of agents selected and configured to wirelessly transmit a communication signal to a client, wherein the first group of agents is capable of forming a radiation beam carrying the communication signal vectored substantially toward the client, and a second group of agents selected and configured to wirelessly broadcast communication signal interference, wherein the second group of agents is capable of forming a radiation beam not vectored substantially toward the client. Consequently, the first group of agents securely communicates with the client and the second group of agents suppresses the ability of an unauthorized, eavesdropping receiver from intercepting the communications signal.
FILED Thursday, March 18, 2021
APPL NO 17/205355
ART UNIT 2467 — Multiplex and VoIP
CURRENT CPC
Wireless Communication Networks
H04W 16/28 (20130101)
H04W 72/08 (20130101) Original (OR) Class
H04W 72/046 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11583814 Bromberg et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) MAAT Energy Company (Cambridge, Massachusetts)
ASSIGNEE(S) MAAT Energy Company (Cambridge, Massachusetts)
INVENTOR(S) Leslie Bromberg (Sharon, Massachusetts);  Kim-Chinh Tran (Cambridge, Massachusetts);  Jorj Ian Owen (Dulles, Virginia);  Jonathan Whitlow (Melbourne Beach, Florida)
ABSTRACT Devices and methods for reducing the specific energy required to reform or pyrolyze reactants in plasmas operating at high flow rates and high pressures are presented. These systems and methods include 1) introducing electrons and/or easily ionized materials to a plasma reactor, 2) increasing turbulence and swirl velocity of the flows of feed gases to have improved mixing in a plasma reactor, and 3) reducing slippage from a plasma reactor system. Such plasma systems may allow plasma reactors to operate at lower temperatures, higher pressure, with improved plasma ignition, increased throughput and improved energy efficiency. In preferred embodiments, the plasma reactors are used to produce hydrogen and carbon monoxide, hydrogen and carbon, or carbon monoxide through reforming and pyrolysis reactions. Preferred feedstocks include methane, carbon dioxide, and other hydrocarbons.
FILED Tuesday, February 25, 2020
APPL NO 17/433131
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 4/001 (20130101)
B01J 6/008 (20130101) Original (OR) Class
B01J 8/0278 (20130101)
B01J 19/088 (20130101)
B01J 19/126 (20130101)
B01J 19/129 (20130101)
B01J 19/2405 (20130101)
B01J 2219/00159 (20130101)
B01J 2219/0847 (20130101)
B01J 2219/0849 (20130101)
B01J 2219/0892 (20130101)
B01J 2219/0898 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/26 (20130101)
C01B 3/382 (20130101)
C01B 2203/0205 (20130101)
C01B 2203/0277 (20130101)
C01B 2203/0861 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583875 Fedorov
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Andrei G. Fedorov (Atlanta, Georgia)
ABSTRACT Embodiments of the present disclosure provide for methods and systems for making structures using an electrospray system while under vacuum. In particular, embodiments of the present disclosure provide for methods and systems for ultra-fast growth of high aspect ratio nano/meso/micro-structures with three dimensional topological complexity and control of phase and composition of the structure formed.
FILED Tuesday, April 06, 2021
APPL NO 17/223620
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 5/16 (20130101) Original (OR) Class
B05B 5/035 (20130101)

Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/04 (20130101)
B05D 3/068 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/145 (20190501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583933 Ripley
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Security Complex and PANTEX Plant (Y-12)
NNSA Critical Mission Site
Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
APPLICANT(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Edward B. Ripley (Knoxville, Tennessee)
ABSTRACT A method of efficiently forming a finished part, the method includes providing a cutting tool having a first cutting edge extending from a first end of the cutting tool, a second cutting edge extending from a second end of the cutting tool, and a shaping edge disposed between the first cutting edge and the second cutting edge. The cutting tool is advanced into a rotating workpiece such that the first cutting edge removes a trailing end of the rotating workpiece, the shaping edge shapes a working portion of the rotating workpiece, and the second cutting edge removes the working portion of the rotating workpiece to form the finished part.
FILED Monday, February 24, 2020
APPL NO 16/798525
ART UNIT 3722 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Turning; Boring
B23B 1/00 (20130101)
B23B 27/04 (20130101)
B23B 27/06 (20130101) Original (OR) Class
B23B 2220/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584658 Hagelin-Weaver et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Helena Hagelin-Weaver (Gainesville, Florida);  Samantha Roberts (Hillsboro, Oregon);  Nathan Carr (Bradenton, Florida)
ABSTRACT The present disclosure provides for compositions, methods of making compositions, and methods of using the composition. In an aspect, the composition can be a reactive material that can be used to split a gas such as water or carbon dioxide.
FILED Wednesday, April 27, 2022
APPL NO 17/730736
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 3/061 (20130101)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 17/10 (20200101)
C01F 17/224 (20200101)
C01F 17/241 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584841 Grubelich et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Mark C. Grubelich (Albuquerque, New Mexico);  Erica Marie Redline (Albuquerque, New Mexico)
ABSTRACT The present invention relates to fluid-infused elastomers that outperform their non-infused base elastomer in harsh environmental conditions. These fluid-infused polymers may be used in applications including geothermal technologies where the oil-infused elastomers may be subject to harsh conditions.
FILED Thursday, September 19, 2019
APPL NO 16/576517
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 7/065 (20130101)
C08J 2327/12 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584860 Zalich et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) The Regents of the University of California (Oakland, California);  PPG Industries Ohio, Inc. (Cleveland, Ohio)
ASSIGNEE(S) PPG Industries Ohio, Inc. (Cleveland, Ohio);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Michael Andrew Zalich (Wexford, Pennsylvania);  Michael F. Baxter (New Kensington, Pennsylvania);  Paul H. Berdahl (Walnut Creek, California);  Stuart D. Hellring (Pittsburgh, Pennsylvania);  Jeffrey Lynn Stalker (Wexford, Pennsylvania)
ABSTRACT The present invention provides for a composition comprising a pigment, wherein the composition is suitable for coating a surface that is, or is expected to be, exposed to the sun. The pigment comprises particles that fluoresce in sunlight, thereby remaining cooler in the sun than coatings pigmented with non-fluorescent particles. The particles comprise solids that fluoresce or glow in the visible or near infrared (NIR) spectra, or that fluoresce when doped. Suitable dopants include, but are not limited to, ions of rare earths and transition metals. A coating composition includes: (i) a film-forming resin; (ii) an infrared reflective pigment; and (iii) an infrared fluorescent pigment different from the infrared reflective pigment. When the coating composition is cured to form a coating and exposed to radiation comprising fluorescence-exciting radiation, the coating has a greater effective solar reflectance (ESR) compared to the same coating exposed to the radiation comprising fluorescence-exciting radiation except without the infrared fluorescent pigment. A multi-layer coating including the coating composition, and a substrate at least partially coated with the coating composition is also disclosed. A method of reducing temperature of an article includes applying the coating composition to at least a portion of the article.
FILED Friday, January 29, 2021
APPL NO 17/162284
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 3/06 (20130101)
B05D 5/06 (20130101)
B05D 7/14 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/22 (20130101)
C08K 3/34 (20130101)
C08K 9/02 (20130101)
C08K 2003/2206 (20130101)
C08K 2003/2227 (20130101)
C08K 2003/2248 (20130101)
C08K 2003/2251 (20130101)
C08K 2201/014 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/004 (20130101)
C09D 5/22 (20130101) Original (OR) Class
C09D 5/32 (20130101)
C09D 5/38 (20130101)
C09D 7/61 (20180101)
C09D 7/62 (20180101)
C09D 127/16 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/02 (20130101)
C09K 11/54 (20130101)
C09K 11/64 (20130101)
C09K 11/562 (20130101)
C09K 11/685 (20130101)
C09K 11/883 (20130101)
C09K 11/7704 (20130101)
C09K 11/7772 (20130101)
C09K 11/77062 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584885 Tyagi et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Mohit Tyagi (Mumbai, India);  Merry Koschan (Knoxville, Tennessee);  Charles L. Melcher (Oak Ridge, Tennessee);  Samuel Bradley Donnald (Millington, Tennessee)
ABSTRACT A method of tailoring the properties of garnet-type scintillators to meet the particular needs of different applications is described. More particularly, codoping scintillators, such as Gd3Ga3Al2O12, Gd3Ga2Al3O12, or other rare earth gallium aluminum garnets, with different ions can modify the scintillation light yield, decay time, rise time, energy resolution, proportionality, and/or sensitivity to light exposure. Also provided are the codoped garnet-type scintillators themselves, radiation detectors and related devices comprising the codoped garnet-type scintillators, and methods of using the radiation detectors to detect gamma rays, X-rays, cosmic rays, and particles having an energy of 1 keV or greater.
FILED Thursday, January 23, 2014
APPL NO 14/762845
ART UNIT 2884 — Optics
CURRENT CPC
Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/7706 (20130101) Original (OR) Class
C09K 11/7774 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 15/04 (20130101)
C30B 29/28 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/2023 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 2004/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584919 McKnight et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Timothy E. McKnight (Greenback, Tennessee);  David E. Graham (Knoxville, Tennessee);  Robert F. Standaert (Knoxville, Tennessee);  Linda A. Lewis (Andersonville, Tennessee);  Samuel A. Lewis (Andersonville, Tennessee)
ABSTRACT A capsule composition comprising: (a) a polyester shell having a thickness of no more than 20 microns, and (b) a solution containing a visual and/or olfactory indicator, wherein the solution is encapsulated by the polyester shell. Also described herein is a method for detecting alpha particle radiation, in which: (i) the capsule composition is placed in contact with an esterase in a location where the presence of alpha particle radiation is being determined; (ii) waiting a period of time for the esterase to degrade the polyester shells, wherein the period of time is insufficient for the esterase to cause leakage of the solution in the absence of alpha particle radiation but is sufficient for alpha particle radiation, if present, to cause leakage from the capsule composition; and (iii) observing whether leakage has occurred at the end of the period of time to determine whether alpha particle radiation is present.
FILED Tuesday, January 21, 2020
APPL NO 16/748039
ART UNIT 2884 — Optics
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/625 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/44 (20130101)

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 11/12 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 2021/6439 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/1606 (20130101)
G01T 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584928 Gill et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado);  Inscripta, Inc. (Boulder, Colorado)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado);  INSCRIPTA, INC. (Boulder, Colorado)
INVENTOR(S) Ryan T. Gill (Denver, Colorado);  Andrew Garst (Boulder, Colorado);  Tanya Elizabeth Warnecke Lipscomb (Boulder, Colorado);  Marcelo Colika Bassalo (Boulder, Colorado);  Ramsey Ibrahim Zeitoun (San Francisco, California)
ABSTRACT Provided herein are methods and composition for trackable genetic variant libraries. Further provided herein are methods and compositions for recursive engineering. Further provided herein are methods and compositions for multiplex engineering. Further provided herein are methods and compositions for enriching for editing and trackable engineered sequences and cells using nucleic acid-guided nucleases.
FILED Thursday, March 07, 2019
APPL NO 16/295393
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 15/102 (20130101)
C12N 15/102 (20130101)
C12N 15/1065 (20130101) Original (OR) Class
C12N 15/1079 (20130101)
C12N 15/1082 (20130101)
C12N 2310/20 (20170501)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 2563/179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585000 Balema et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Viktor Balema (Ames, Iowa);  Sonal Padalkar (Ames, Iowa);  Ihor Hlova (Ames, Iowa);  Tian Lan (Ames, Iowa);  Oleksandr Dolotko (Ames, Iowa);  Vitalij K. Pecharsky (Ames, Iowa);  Duane D. Johnson (Ames, Iowa);  Arjun K. Pathak (Ames, Iowa);  Prashant Singh (Jaipur, India)
ABSTRACT A cathode is provided for electrolysis of water wherein the cathode material comprises a multi-principal element, transition metal dichalcogenide material that has four or more chemical elements and that is a single phase, solid solution. The pristine cathode material does not contain platinum as a principal (major) component. However, a cathode comprising a transition metal dichalcogenide having platinum (Pt) nanosized islands or precipitates disposed thereon is also provided.
FILED Tuesday, October 01, 2019
APPL NO 16/602420
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/42 (20130101)
C23C 18/1639 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/04 (20130101)
C25B 11/051 (20210101)
C25B 11/057 (20210101)
C25B 11/075 (20210101) Original (OR) Class
C25B 11/091 (20210101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/50 (20130101)
C25D 5/02 (20130101)
C25D 13/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585363 Briggs et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Timothy Briggs (Brentwood, California);  Kyle James LeBlanc (Berkeley, California);  Brian K. Holliday (Stockton, California)
ABSTRACT A rivet assembly for securing a wire in electrical communication with a substrate having a hollow cylindrical body with a first opening at a proximal end and a second opening at a distal end. The rivet assembly further includes a wire with a portion in electrical communication with the cylindrical body. The rivet assembly yet further includes a compression mechanism configured for use selectively compressing the cylindrical body along an axial direction. Compression of the cylindrical body can cause diametric expansion of an outer diameter of the cylindrical body to retain the cylindrical body within a substrate. The rivet assembly additionally includes wire retention structure configured for holding the wire in electrical contact with the compressed cylindrical body.
FILED Thursday, October 22, 2020
APPL NO 17/077254
ART UNIT 2841 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 19/1045 (20130101) Original (OR) Class

Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 4/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585622 Duque et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Amanda Lynn Duque (Los Alamos, New Mexico);  William Lee Perry (Los Alamos, New Mexico)
ABSTRACT Microwave ignition systems with a launcher affixed to or located within a gun spindle. Use of a planar, impedance matched system that include a launcher affixed to or located within a gun spindle and a receiver affixed the propelling charge, where the receiver is engineered and impedance matched to efficiently deposit energy into the receiving igniter material, may result in significantly better timing and reliability than conventional mechanical gun ignition systems and other microwave ignition systems. A pressure-tolerant feed through system can route the microwave energy to the inside of the breech.
FILED Thursday, April 30, 2020
APPL NO 16/864021
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 19/63 (20130101) Original (OR) Class

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 5/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585692 Kiesel et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
Office of Electricity (DOE-OE)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California);  General Electric Company (Schenectady, New York)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California);  General Electric Company (Schenectady, New York)
INVENTOR(S) Peter Kiesel (Palo Alto, California);  Ajay Raghavan (Mountain View, California);  Todd Karin (Fairfield, California);  Qiushu Chen (San Jose, California);  Malcolm G. Smith, Jr. (Haughton, Louisiana);  Robert T. Stinson, IV (Stonewall, Louisiana)
ABSTRACT A sensor system includes a sensor network comprising at least one optical fiber having one or more optical sensors. At least one of the optical sensors is arranged to sense vibration of an electrical device and to produce a time variation in light output in response to the vibration. A detector generates an electrical time domain signal in response to the time variation in light output. An analyzer acquires a snapshot frequency component signal which comprises one or more time varying signals of frequency components of the time domain signal over a data acquisition time period. The analyzer detects a condition of the electrical device based on the snapshot frequency component signal.
FILED Monday, January 27, 2020
APPL NO 16/773181
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 5/35316 (20130101)
G01D 5/35374 (20130101)

Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 9/004 (20130101) Original (OR) Class
G01H 13/00 (20130101)

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 11/3206 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/246 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 27/12 (20130101)
H01F 27/14 (20130101)
H01F 2027/406 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585753 McCartt et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Daniel McCartt (Johnson City, Tennessee);  Jun Jiang (Fremont, California)
ABSTRACT In one aspect, a method of detecting a trace gas is disclosed. The method includes containing the trace gas in an optical cavity. The method further includes injecting a first laser light from a first laser into the optical cavity causing the trace gas to transition from an energy state lower that a first excited energy state to the first excited energy state, and injecting a second laser light from a second laser into the optical cavity causing the trace gas to transition from the first excited energy state to a second excited energy state. The method includes measuring, by a detector, a first cavity ringdown intensity as a function of time after turning off the second laser with the first laser on, and a second cavity ringdown intensity as a function of time after turning off the second laser with the first laser off.
FILED Wednesday, March 30, 2022
APPL NO 17/709222
ART UNIT 2877 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/42 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/39 (20130101) Original (OR) Class
G01N 2021/391 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585771 Iftime et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
Methane Observation Networks with Innovative Technology to Obtain Reductions (MONITOR)
System of Printed Hybrid Intelligent Nano-Chemical Sensors (SPHINCS)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Gabriel Iftime (Dublin, California);  Clinton Smith (San Francisco, California);  David Eric Schwartz (San Carlos, California);  Yong Zhang (Millbrae, California);  Vedasri Vedharathinam (Sunnyvale, California)
ABSTRACT Disclosed herein are methods of producing metal nanoparticle-decorated carbon nanotubes. The methods include forming a reaction mixture by combining a first solution with a second solution, wherein the first solution comprises polymer-coated metal nanoparticles comprising metallic nanoparticles coated with a polymer, and wherein the second solution comprises carbon nanotubes. The methods also include heating the reaction mixture to a temperature greater than a glass transition temperature of the polymer for a time sufficient to cause the polymer-coated metal nanoparticles to bind to the carbon nanotubes forming the metal nanoparticle-decorated carbon nanotubes.
FILED Tuesday, February 22, 2022
APPL NO 17/677716
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/205 (20130101)
B01J 20/0225 (20130101)
B01J 20/327 (20130101)
B01J 20/3204 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/054 (20220101)
B22F 1/054 (20220101)
B22F 1/054 (20220101)
B22F 1/102 (20220101)
B22F 1/102 (20220101)
B22F 9/24 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Alloys
C22C 2026/002 (20130101)
C22C 2026/002 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/04 (20130101) Original (OR) Class
G01N 27/126 (20130101)
G01N 27/127 (20130101)
G01N 33/0009 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585792 Van Berkel
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Gary J. Van Berkel (Oak Ridge, Tennessee)
ABSTRACT A system for sampling a sample material includes a probe which can have an outer probe housing with an open end. A liquid supply conduit within the housing has an outlet positioned to deliver liquid to the open end of the housing. The liquid supply conduit can be connectable to a liquid supply for delivering liquid at a first volumetric flow rate to the open end of the housing. A liquid exhaust conduit within the housing is provided for removing liquid from the open end of the housing. A liquid exhaust system can be provided for removing liquid from the liquid exhaust conduit at a second volumetric flow rate. A droplet dispenser can dispense drops of a sample or a sample-containing solvent into the open end of the housing. A sensor and a processor can be provided to monitor and maintain a liquid dome present at the open end.
FILED Tuesday, April 26, 2022
APPL NO 17/729701
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/44 (20130101)
A61B 5/443 (20130101)
A61B 5/4845 (20130101)
A61B 10/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/00 (20130101)
G01N 1/20 (20130101)
G01N 30/7233 (20130101) Original (OR) Class
G01N 35/1095 (20130101)
G01N 2001/028 (20130101)
G01N 2001/045 (20130101)
G01N 2030/027 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0404 (20130101)
H01J 49/0431 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585841 Jau
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Yuan-Yu Jau (Albuquerque, New Mexico)
ABSTRACT In a method of atomic electrometry, EIT spectroscopy is performed on host atoms of an alkali metal in a vapor cell. The EIT spectroscopy indicates a resonant energy of a probed Rydberg state of the host atoms. The vapor cell is exposed to an ambient electric field. A shift in the resonant energy as indicated by the EIT spectroscopy is observed and interpreted as a measurement of the ambient field. During the measurement of the ambient field, a bias electric field is generated inside the vapor cell by shining light into the vapor cell from a light source situated outside of the cell. The bias field is useful for increasing the sensitivity of the measurement.
FILED Friday, November 19, 2021
APPL NO 17/531306
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 29/0885 (20130101) Original (OR) Class
G01R 29/0892 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585933 Panas
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Robert Matthew Panas (Dublin, California)
ABSTRACT The present disclosure relates to a mapping system adapted for detecting objects in an environmental scene, by scanning an environmental scene with propagating energy, and receiving reflected energy back from objects present in the environmental scene, in a prioritized manner, for later use. The system may comprise an imaging subsystem which includes a detection and ranging subsystem for initially identifying primitive objects in the environmental scene. The imaging subsystem may also include an identification and mapping subsystem for prioritizing the primitive objects for further scanning and analysis, to ultimately identify one or more of the primitive objects as one or more abstract objects. An environmental model, updated in real time, is used to maintain a map of the primitive objects and the known abstract objects within the environmental scene, as new primitive objects and new abstract objects are obtained with repeated scans of the environmental scene.
FILED Thursday, September 05, 2019
APPL NO 16/561787
ART UNIT 2865 — Printing/Measuring and Testing
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4802 (20130101)
G01S 7/4808 (20130101)
G01S 17/89 (20130101) Original (OR) Class
G01S 17/931 (20200101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/6288 (20130101)

Image or Video Recognition or Understanding
G06V 20/56 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586256 Bermudez Rodriguez et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Sergio A. Bermudez Rodriguez (Croton-On-Hudson, New York);  Hendrik F. Hamann (Yorktown Heights, New York);  Hans-Dieter Wehle (Horb Talheim, Germany)
ABSTRACT Methods and systems for data center management include collecting sensor data from one or more sensors in a rack; determining a location and identifying information for each asset in the rack using a set of asset tags associated with respective assets; communicating the sensor and asset location to a communication module; receiving an instruction from the communication module; and executing the received instruction to change a property of the rack.
FILED Monday, September 18, 2017
APPL NO 15/706885
ART UNIT 3687 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Electric Digital Data Processing
G06F 1/18 (20130101) Original (OR) Class
G06F 1/28 (20130101)
G06F 1/206 (20130101)
G06F 1/3206 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)
G06Q 10/083 (20130101)
G06Q 10/087 (20130101)
G06Q 30/06 (20130101)
G06Q 30/0635 (20130101)

Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use
Y02D 10/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586441 Kalamatianos et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) John Kalamatianos (Boxborough, Massachusetts);  Jagadish B. Kotra (Austin, Texas)
ABSTRACT Systems, apparatuses, and methods for virtualizing a micro-operation cache are disclosed. A processor includes at least a micro-operation cache, a conventional cache subsystem, a decode unit, and control logic. The decode unit decodes instructions into micro-operations which are then stored in the micro-operation cache. The micro-operation cache has limited capacity for storing micro-operations. When new micro-operations are decoded from pending instructions, existing micro-operations are evicted from the micro-operation cache to make room for the new micro-operations. Rather than being discarded, micro-operations evicted from the micro-operation cache are stored in the conventional cache subsystem. This prevents the original instruction from having to be decoded again on subsequent executions. When the control logic determines that micro-operations for one or more fetched instructions are stored in either the micro-operation cache or the conventional cache subsystem, the control logic causes the decode unit to transition to a reduced-power state.
FILED Thursday, December 17, 2020
APPL NO 17/125730
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3824 (20130101) Original (OR) Class
G06F 9/30145 (20130101)
G06F 12/0875 (20130101)
G06F 12/0897 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586539 Na et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Weon Taek Na (Bellevue, Washington);  Jagadish B. Kotra (Austin, Texas);  Yasuko Eckert (Bellevue, Washington);  Steven Raasch (Boxborough, Massachusetts);  Sergey Blagodurov (Bellevue, Washington)
ABSTRACT A processing system selectively allocates space to store a group of one or more cache lines at a cache level of a cache hierarchy having a plurality of cache levels based on memory access patterns of a software application executing at the processing system. The processing system generates bit vectors indicating which cache levels are to allocate space to store groups of one or more cache lines based on the memory access patterns, which are derived from data granularity and movement information. Based on the bit vectors, the processing system provides hints to the cache hierarchy indicating the lowest cache level that can exploit the reuse potential for a particular data.
FILED Friday, December 13, 2019
APPL NO 16/713940
ART UNIT 2133 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 9/30036 (20130101)
G06F 12/0811 (20130101) Original (OR) Class
G06F 12/0831 (20130101)
G06F 12/0871 (20130101)
G06F 12/0882 (20130101)
G06F 12/1027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586905 Song et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Arizona Board of Regents (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona);  LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Huan Song (Tempe, Arizona);  Jayaraman Thiagarajan (Dublin, California);  Andreas Spanias (Tempe, Arizona)
ABSTRACT A method including receiving an input data set. The input data set can include one of a feature domain set or a kernel matrix. The method also can include constructing dense embeddings using: (i) Nyström approximations on the input data set when the input data set comprises the kernel matrix, and (ii) clustered Nyström approximations on the input data set when the input data set comprises the feature domain set. The method additionally can include performing representation learning on each of the dense embeddings using a multi-layer fully-connected network for each of the dense embeddings to generate latent representations corresponding to each of the dense embeddings. The method further can include applying a fusion layer to the latent representations corresponding to the dense embeddings to generate a combined representation. The method additionally can include performing classification on the combined representation. Other embodiments of related systems and methods are also disclosed.
FILED Friday, October 05, 2018
APPL NO 16/152841
ART UNIT 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Electric Digital Data Processing
G06F 17/16 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587646 Colby et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Sean M. Colby (Richland, Washington);  Ryan S. Renslow (Richland, Washington)
ABSTRACT A variational autoencoder (VAE) has been developed to learn a continuous numerical, or latent, representation of molecular structure to expand reference libraries for small molecule identification. The VAE has been extended to include a chemical property decoder, trained as a multitask network, to shape the latent representation such that it assembles according to desired chemical properties. The approach is unique in its application to metabolomics and small molecule identification, focused on properties that are obtained from experimental measurements (m/z, CCS) paired with its training paradigm, which involves a cascade of transfer learning iterations. First, molecular representation is learned from a large dataset of structures with m/z labels. Next, in silico property values are used to continue training. Finally, the network is further refined by being trained with the experimental data. The trained network is used to predict chemical properties directly from structure and generate candidate structures with desired chemical properties. The network is extensible to other training data and molecular representations, and for use with other analytical platforms, for both chemical property and feature prediction as well as molecular structure generation.
FILED Tuesday, December 03, 2019
APPL NO 16/702119
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 20/10 (20190101)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/20 (20190201) Original (OR) Class
G16C 20/30 (20190201)
G16C 20/60 (20190201)
G16C 20/70 (20190201)
G16C 60/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587689 Griffith et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) George W. Griffith (Idaho Falls, Idaho);  Isabella J. van Rooyen (Idaho Falls, Idaho)
ABSTRACT A nuclear fuel element includes a core comprising a fissile element and an additional element. A protective structure surrounds the core and comprises at least a first material surrounding the nuclear fuel. The first material comprises the fissile element and the additional element and comprises a greater than stoichiometric amount of the additional element. An outer portion of the nuclear fuel element comprises a metal. Related nuclear fuel elements, and related methods are also disclosed.
FILED Friday, October 16, 2020
APPL NO 17/072903
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Nuclear Reactors
G21C 3/20 (20130101) Original (OR) Class
G21C 3/28 (20130101)
G21C 3/623 (20130101)
G21C 3/626 (20130101)
G21C 21/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587694 Despotopulos et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) John Despotopulos (Livermore, California);  Carlos Valdez (San Ramon, California);  Kelly Nora Kmak (Berkeley, California)
ABSTRACT Provided herein are methods of isolating and using radioactive mercury. In particular, provided herein are methods of isolating radioactive mercury including the use of a thiacrown ether, and using the isolated radioactive mercury in therapeutic and/or imaging applications.
FILED Thursday, March 12, 2020
APPL NO 16/816822
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1001 (20130101)
A61N 2005/1019 (20130101)

Conversion of Chemical Elements; Radioactive Sources
G21G 1/001 (20130101) Original (OR) Class
G21G 4/08 (20130101)
G21G 2001/0094 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587701 Van Der Laan
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Advanced Conductor Technologies LLC (Boulder, Colorado)
ASSIGNEE(S) ADVANCED CONDUCTOR TECHNOLOGIES LLC (Boulder, Colorado)
INVENTOR(S) Daniël Cornelis Van Der Laan (Longmont, Colorado)
ABSTRACT A superconducting device includes a superconducting cable having a plurality of superconducting tapes in a plurality of phases, including a first phase, and at least one further phase. One or more superconducting tapes of the first phase is in electrical contact with one or more superconducting tapes of the at least one further phase through at least one resistive barrier that prevents current from passing between the first phase and the at least one further phase in the absence of a voltage between one or more of the superconducting tapes of the first phase or the at least one further phase. The first phase is electrically connected in series to at least one further phase.
FILED Tuesday, December 03, 2019
APPL NO 16/702521
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/3815 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 3/12 (20130101)
H01B 3/18 (20130101)
H01B 9/04 (20130101)
H01B 12/02 (20130101) Original (OR) Class
H01B 12/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587741 Raman et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Tesla, Inc. (Austin, Texas)
ASSIGNEE(S) Tesla, Inc. (Austin, Texas)
INVENTOR(S) Santhanam Raman (San Diego, California);  James Borkenhagen (Spring Valley, California);  Xiaomei Xi (Carlsbad, California);  Xiang-Rong Ye (San Diego, California)
ABSTRACT An energy storage device can include a cathode, an anode, and a separator between the cathode and the anode, where the anode and/or electrode includes an electrode film having a super-fibrillized binder material and carbon. The electrode film can have a reduced quantity of the binder material while maintaining desired mechanical and/or electrical properties. A process for fabricating the electrode film may include a fibrillization process using reduced speed and/or increased process pressure such that fibrillization of the binder material can be increased. The electrode film may include an electrical conductivity promoting additive to facilitate decreased equivalent series resistance performance. Increasing fibrillization of the binder material may facilitate formation of thinner electrode films, such as dry electrode films.
FILED Thursday, February 11, 2021
APPL NO 17/173748
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/06 (20130101)
H01G 11/28 (20130101)
H01G 11/38 (20130101)
H01G 11/42 (20130101) Original (OR) Class
H01G 11/50 (20130101)
H01G 11/52 (20130101)
H01G 11/86 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/043 (20130101)
H01M 4/133 (20130101)
H01M 4/0416 (20130101)
H01M 4/587 (20130101)
H01M 4/621 (20130101)
H01M 4/625 (20130101)
H01M 10/0525 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588747 Ros-Giralt et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Reservoir Labs, Inc. (New York, New York)
ASSIGNEE(S) Reservoir Labs, Inc. (San Diego, California)
INVENTOR(S) Jordi Ros-Giralt (Newport Beach, California);  Alan Commike (San Jose, California);  Peter Cullen (New York, New York);  Richard A. Lethin (New York, New York)
ABSTRACT In a network system, an application receiving packets can consume one or more packets in two or more stages, where the second and the later stages can selectively consume some but not all of the packets consumed by the preceding stage. Packets are transferred between two consecutive stages, called producer and consumer, via a fixed-size storage. Both the producer and the consumer can access the storage without locking it and, to facilitate selective consumption of the packets by the consumer, the consumer can transition between awake and sleep modes, where the packets are consumed in the awake mode only. The producer may also switch between awake and sleep modes. Lockless access is made possible by controlling the operation of the storage by the producer and the consumer both according to the mode of the consumer, which is communicated via a shared memory location.
FILED Monday, May 10, 2021
APPL NO 17/315933
ART UNIT 2463 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 47/30 (20130101)
H04L 47/58 (20130101) Original (OR) Class
H04L 47/521 (20130101)
H04L 49/9031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11589164 Zettl et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alexander K. Zettl (Kensington, California);  Stephen M. Gilbert (Albany, California);  Donez J. Horton-Bailey (El Cerrito, California);  Hu Long (El Cerrito, California)
ABSTRACT This disclosure provides systems, methods, and apparatus related to acoustic transducers.
FILED Tuesday, August 06, 2019
APPL NO 17/266539
ART UNIT 2651 — Videophones and Telephonic Communications
CURRENT CPC
Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 7/06 (20130101) Original (OR) Class
H04R 7/18 (20130101)
H04R 19/02 (20130101)
H04R 19/005 (20130101)
H04R 2307/023 (20130101)
H04R 2307/204 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11582971 Yang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) Jingxiang Yang (New York, New York);  Xiaolong Zhu (New York, New York);  Bart Kahr (Brooklyn, New York);  Michael D. Ward (New York, New York)
ABSTRACT The present invention relates to a novel crystalline form of deltamethrin, which is a pyrethroid compound useful as a pest control agent. The present invention further relates to a process of preparing the novel crystalline form, and to methods of controlling pests using the novel crystalline form.
FILED Friday, September 25, 2020
APPL NO 17/032254
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 25/12 (20130101)
A01N 25/34 (20130101)
A01N 53/00 (20130101) Original (OR) Class

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/13 (20130101)

Acyclic or Carbocyclic Compounds
C07C 255/41 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583228 Jur et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S) North Carolina State University (Raleigh, North Carolina)
INVENTOR(S) Jesse S. Jur (Raleigh, North Carolina);  Amanda C. Myers (Raleigh, North Carolina);  Allison Bowles (Raleigh, North Carolina);  Raj Bhakta (Raleigh, North Carolina);  Braden M. Li (Raleigh, North Carolina);  Elizabeth Cobarrubias (Raleigh, North Carolina);  Michael Lim (Raleigh, North Carolina)
ABSTRACT Described herein are functionalized garments that can be worn on the torso of a subject and can be configured with varying zones or areas of compressions and can provide increased signal-to-noise ratios and reduced motion artifacts in areas while allowing a substantially unimpeded freedom of motion.
FILED Friday, February 07, 2020
APPL NO 16/784297
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/2415 (20210101)
A61B 5/6805 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 1/163 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583572 Weiss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Michael Weiss (Moreland Hills, Ohio);  Jonathan Pokorski (Cleveland, Ohio)
ABSTRACT An insulin composition comprises an insulin analogue and polymer blend. The insulin analogue contains cysteine substitutions at positions B4 and A10 (to form cystine B4-A10), and one or more additional substitutions selected from the group consisting of: a connecting domain of 5-11 amino acids between insulin A- and B domains; a non-beta-branched amino-acid substitution at position A8; a non-beta-branched acidic or polar side chain at position A14; a halogenic modification of PheB24 at the ortho position; and substitution of lysine at position B29 by Glu, Ala, Val, Ile, Leu, amino-propionic acid, amino-butryic acid, or Norleucine. The insulin analogue is compatible with a process of manufacture that includes one or more steps within the temperature range 90-120° C. The encapsulated insulin analogue may optionally contain free PEG or be PEGylated. The insulin analogue-encapsulated polymer blend may be cast as a microneedle patch for topical administration or as micropellets for subcutaneous injection.
FILED Friday, December 23, 2016
APPL NO 16/065596
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0021 (20130101)
A61K 38/28 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583819 Lopez et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Duke University (Durham, North Carolina);  UNM Rainforest Innovations (Albuquerque, New Mexico)
ASSIGNEE(S) UNM Rainforest Innovations (Albuquerque, New Mexico);  Duke University (Durham, North Carolina)
INVENTOR(S) Gabriel P. Lopez (Durham, North Carolina);  Joseph R. Simon (Durham, North Carolina);  Nick J. Carroll (Durham, North Carolina);  Ashutosh Chilkoti (Durham, North Carolina)
ABSTRACT Nano- to microscale liquid coacervate particles are provided. The liquid coacervate particles are produced by a process including stimulating a population of liquid droplets containing one or a mixture of components to induce a phase separation point of a first component, and maintaining stimulation at the phase separation point to form a coacervate domain of the first component within each of the droplets to form the liquid coacervate particles. The self-assembled nano, meso, micro and macro liquid coacervate particles and related coated substrates can have utility in drug delivery, bioanalytical systems, controlled cell culture, tissue engineering, biomanufacturing and drug discovery.
FILED Thursday, March 12, 2020
APPL NO 16/817299
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/146 (20130101)
A61K 38/00 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/34 (20130101)
A61L 27/54 (20130101)
A61L 29/085 (20130101)
A61L 31/10 (20130101)
A61L 31/16 (20130101)
A61L 2300/62 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 2/00 (20130101)
B01J 2/06 (20130101)
B01J 13/06 (20130101) Original (OR) Class

Peptides
C07K 14/78 (20130101)
C07K 19/00 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584021 Nguyen et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Pham Nguyen (Mesa, Arizona);  Wenlong Zhang (Mesa, Arizona);  Panagiotis Polygerinos (Gilbert, Arizona);  Francisco Lopez Arellano (Phoenix, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Pham Nguyen (Mesa, Arizona);  Wenlong Zhang (Mesa, Arizona);  Panagiotis Polygerinos (Gilbert, Arizona);  Francisco Lopez Arellano (Phoenix, Arizona)
ABSTRACT A soft robot hand includes a palm, a first fabric-reinforced textile actuator coupled to the palm, and a second fabric-reinforced textile actuator coupled to the palm. The first actuator is moveable relative to the palm between a collapsed position and an inflated position to approximate a joint in a first human finger. The second actuator is spaced apart from the first actuator. The second actuator is moveable relative to the palm between a collapsed position and an inflated position to approximate a joint in a second human finger.
FILED Friday, May 15, 2020
APPL NO 16/875047
ART UNIT 3651 — Material and Article Handling
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/14 (20130101)
B25J 15/0009 (20130101) Original (OR) Class
B25J 15/12 (20130101)
B25J 15/024 (20130101)

Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials
D06M 15/564 (20130101)
D06M 2101/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584637 Langford et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) William Kai Langford (Cambridge, Massachusetts);  Amanda Ghassaei (Cambridge, Massachusetts);  Neil Gershenfeld (Cambridge, Massachusetts)
ABSTRACT A system of flexural, actuating, and semiconducting elements of part-types necessary to assemble actuated robotic systems. These parts are joined with a common interface, interlocking with neighboring parts to form a regular lattice structure. Primary considerations for the design of the part interfaces include ease of assembly and the ability to transfer mechanical loads and electronic signals to neighboring parts. The parts are designed to be assembled vertically so structures can he built incrementally one part at a time. They can be easily fabricated at a range of length-scales using a variety of two-dimensional manufacturing processes. These processes include, for example, stamping and laminating, which enable high-throughput production. The simple mechanical interfaces between parts also enable disassembly allowing for reconfigurability and reuse. The interlocking nature of these assemblies allows loads to be distributed through many parallel load-paths.
FILED Thursday, August 23, 2018
APPL NO 16/109947
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0021 (20130101)
B81B 7/0003 (20130101) Original (OR) Class
B81B 2201/13 (20130101)
B81B 2207/07 (20130101)

Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00007 (20130101)

Dynamo-electric Machines
H02K 41/0354 (20130101)

Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils
H02P 7/025 (20160201)
H02P 25/034 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584712 Toscano et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) John Pasquale Toscano (Baltimore, Maryland);  Vinayak S. Khodade (Baltimore, Maryland)
ABSTRACT Alkylamine-substituted perthiocarbamates capable of controllable release of hydropersulfides (RSSH) and carbonyl sulfide (COS) and their use in treating or preventing ischemia-reperfusion injury are described.
FILED Wednesday, February 03, 2021
APPL NO 17/166434
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Acyclic or Carbocyclic Compounds
C07C 321/14 (20130101)
C07C 333/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584937 Wagner et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Doris Wagner (Narberth, Pennsylvania);  Nobutoshi Yamaguchi (Philadelphia, Pennsylvania)
ABSTRACT The invention relates to molecules for controlling plant growth and development. Specifically, the invention relates to molecules comprising a gibberellin activator or a gibberellin inhibitor operably linked to a promoter specific to a lateral organ primordium. The invention also relates to transgenic plants having the transgenic molecules and methods for making such transgenic plants.
FILED Tuesday, April 28, 2015
APPL NO 15/307356
ART UNIT 1662 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0071 (20130101)
C12N 15/827 (20130101) Original (OR) Class
C12N 15/8223 (20130101)
C12N 15/8243 (20130101)

Enzymes
C12Y 114/11 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584986 Abelson et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) John R. Abelson (Urbana, Illinois);  Elham Mohimi (Urbana, Illinois);  Gregory S. Girolami (Urbana, Illinois);  Sumeng Liu (Urbana, Illinois);  Zhejun Zhang (Urbana, Illinois)
ABSTRACT Provided herein are methods for forming a layer on a substrate wherein the layer is formed selectively on a first region of the substrate relative to a second region having a composition different than the first region. Methods of the invention include selectively forming a layer using an inhibitor agent capable of reducing the average acidity of a first region of the substrate having a composition characterized by a plurality of hydroxyl groups. Methods of the invention include selectively forming a layer by exposure of the substrate to: (i) an inhibitor agent comprising a substituted or an unsubstituted amine group, a substituted or an unsubstituted pyridyl group, a carbonyl group, or a combination of these, and (ii) a precursor gas comprising one or more ligands selected from the group consisting of a carbonyl group, an allyl group, combination thereof.
FILED Thursday, November 01, 2018
APPL NO 16/178213
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/04 (20130101) Original (OR) Class
C23C 16/0272 (20130101)
C23C 16/45553 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02271 (20130101)
H01L 21/28194 (20130101)
H01L 21/28562 (20130101)
H01L 21/76843 (20130101)
H01L 21/76849 (20130101)
H01L 21/76895 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585964 Yanik et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ahmet Ali Yanik (Santa Cruz, California);  Ahsan Habib (Santa Cruz, California);  Xiangchao Zhu (Santa Cruz, California)
ABSTRACT An electro-plasmonic array is disclosed. The electro-plasmonic array includes a substrate and a plurality of nanoantennas disposed on a surface of the substrate, each of the electro-plasmonic nanoantennas including a conductive nanodisk and a conforming biocompatible electrochromic polymer layer.
FILED Monday, August 10, 2020
APPL NO 16/989266
ART UNIT 2877 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/658 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/008 (20130101) Original (OR) Class

Antennas, i.e Radio Aerials
H01Q 1/38 (20130101)
H01Q 9/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586062 Partee et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Syght, Inc. (Golden, Colorado)
ASSIGNEE(S) Syght, Inc. (Golden, Colorado)
INVENTOR(S) Charles C. Partee (Golden, Colorado);  Kevin D. McKinstry (Westminster, Colorado)
ABSTRACT An optoelectronic system includes a concentration layer, a modulation layer including an array of light modulators, an exit layer that receives the modulation layer output having a modulation layer output spatial distribution and remaps the modulation layer output spatial distribution to a modified spatial distribution. A collector layer receives the modified spatial distribution to produce a collector layer output. A detector receives the collector layer output. A processor controls the modulation layer and receives the detector output to generate an image. The collector layer can receive the modified spatial distribution at a plurality of collector layer inputs and combine the plurality of collector layer inputs at a collector layer output. Modulators can be configured to direct couple modulated light to a collector layer, without using an exit layer. Configurations with spatial light modulator modules and sub-modules are described.
FILED Wednesday, July 22, 2020
APPL NO 16/936340
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 3/0056 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/09 (20130101) Original (OR) Class
G02F 1/035 (20130101)
G02F 1/092 (20130101)
G02F 1/095 (20130101)
G02F 1/0311 (20130101)
G02F 1/0322 (20130101)
G02F 2201/18 (20130101)
G02F 2203/07 (20130101)
G02F 2203/12 (20130101)

Pictorial Communication, e.g Television
H04N 5/2253 (20130101)
H04N 9/3167 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586075 Wei et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Kent State University (Kent, Ohio)
ASSIGNEE(S) KENT STATE UNIVERSITY (Kent, Ohio)
INVENTOR(S) Qi-Huo Wei (Hudson, Ohio);  Hao Yu (Kent, Ohio);  Yubing Guo (Kent, Ohio);  Miao Jiang (Kent, Ohio);  Oleg D. Lavrentovich (Kent, Ohio)
ABSTRACT A method for aligning molecular orientations of liquid crystals and/or polymeric materials into spatially variant patterns uses metamasks. When non-polarized or circularly polarized light is transmitted through or reflected by the metamasks, spatially varied polarization direction and intensity patterns of light can be generated. By projecting the optical patterns of the metamasks onto substrates coated with photoalignment materials, spatially variant molecular orientations encoded in the polarization and intensity patterns are induced in the photoalignment materials, and transfer into the liquid crystals. Possible designs for the metamask use nanostructures of metallic materials (e.g., rectangular nanocuboids of metallic materials arrayed on a transparent substrate).
FILED Wednesday, February 07, 2018
APPL NO 16/484218
ART UNIT 2871 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)
B82Y 40/00 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 19/56 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/1523 (20130101)
G02F 1/13378 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586884 Yang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) University of Massachusetts (Amherst, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Jianhua Yang (Hadley, Massachusetts);  Qiangfei Xia (Amherst, Massachusetts);  Mark McLean (Severna Park, Maryland);  Qing Wu (Manilus, New York)
ABSTRACT A diffusive memristor device and an electronic device for emulating a biological neuron is disclosed. The diffusive memristor device includes a bottom electrode, a top electrode formed opposite the bottom electrode, and a dielectric layer disposed between the top electrode and the bottom electrode. The dielectric layer comprises an oxide doped with a metal.
FILED Friday, February 08, 2019
APPL NO 16/270848
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/061 (20130101)
G06N 3/063 (20130101) Original (OR) Class
G06N 3/0454 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586905 Song et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Arizona Board of Regents (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona);  LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Huan Song (Tempe, Arizona);  Jayaraman Thiagarajan (Dublin, California);  Andreas Spanias (Tempe, Arizona)
ABSTRACT A method including receiving an input data set. The input data set can include one of a feature domain set or a kernel matrix. The method also can include constructing dense embeddings using: (i) Nyström approximations on the input data set when the input data set comprises the kernel matrix, and (ii) clustered Nyström approximations on the input data set when the input data set comprises the feature domain set. The method additionally can include performing representation learning on each of the dense embeddings using a multi-layer fully-connected network for each of the dense embeddings to generate latent representations corresponding to each of the dense embeddings. The method further can include applying a fusion layer to the latent representations corresponding to the dense embeddings to generate a combined representation. The method additionally can include performing classification on the combined representation. Other embodiments of related systems and methods are also disclosed.
FILED Friday, October 05, 2018
APPL NO 16/152841
ART UNIT 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Electric Digital Data Processing
G06F 17/16 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586968 King et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Atom Computing Inc. (Berkeley, California)
ASSIGNEE(S) ATOM COMPUTING INC. (Berkeley, California)
INVENTOR(S) Jonathan King (Berkeley, California);  Benjamin Bloom (Berkeley, California);  Krish Kotru (Berkeley, California);  Brian Lester (Berkeley, California);  Maxwell Parsons (Berkeley, California)
ABSTRACT The present disclosure provides methods and systems for performing non-classical computations. The methods and systems generally use a plurality of spatially distinct optical trapping sites to trap a plurality of atoms, one or more electromagnetic delivery units to apply electromagnetic energy to one or more atoms of the plurality to induce the atoms to adopt one or more superposition states of a first atomic state and a second atomic state, one or more entanglement units to quantum mechanically entangle at least a subset of the one or more atoms in the one or more superposition states with at least another atom of the plurality, and one or more readout optical units to perform measurements of the superposition states to obtain the non-classical computation.
FILED Wednesday, November 06, 2019
APPL NO 16/676317
ART UNIT 2872 — Optics
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587232 Wick et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) CAMERAD TECHNOLOGIES (Decatur, Georgia);  THE UAB RESEARCH FOUNDATION (Birmingham, Alabama)
ASSIGNEE(S) CAMERAD TECHNOLOGIES (Decatur, Georgia);  THE UAB RESEARCH FOUNDATION (Birmingham, Alabama)
INVENTOR(S) Carson Arthur Wick (Atlanta, Georgia);  Srini Tridandapani (Decatur, Georgia)
ABSTRACT A method for preventing wrong-patient errors includes receiving a selection of a current imaging subject. The current imaging subject is selected for a current image acquisition session comprising capturing one or more current images of the current imaging subject utilizing at least a first image sensor system of a first imaging modality. The method includes accessing one or more previous images of a previous imaging subject. The one or more previous images depict the previous imaging subject according to at least a second imaging modality that is different from the first imaging modality. The method includes presenting the one or more previous images on a display system and, in response to determining that the previous imaging subject matches the current imaging subject based upon the one or more previous images, performing the current image acquisition session.
FILED Friday, May 06, 2022
APPL NO 17/738932
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0035 (20130101)

Electric Digital Data Processing
G06F 3/165 (20130101)

Image Data Processing or Generation, in General
G06T 7/0016 (20130101) Original (OR) Class
G06T 2200/24 (20130101)
G06T 2207/10016 (20130101)
G06T 2207/30004 (20130101)

Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 17/04 (20130101)
G10L 17/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587696 Watkins et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) James Watkins (South Hadley, Massachusetts);  Michael R. Beaulieu (Chicopee, Massachusetts);  Nicholas R. Hendricks (South Deerfield, Massachusetts)
ABSTRACT Aspects relate to patterned nanostructures having a feature size not including film thickness of below 5 microns. The patterned nanostructures are made up of nanoparticles having an average particle size of less than 100 nm. A nanoparticle composition, which, in some cases, includes a binder, is applied to a substrate. A patterned mold used in concert with electromagnetic radiation function to manipulate the nanoparticle composition in forming the patterned nanostructure. In some embodiments, the patterned mold nanoimprints a pattern onto the nanoparticle composition and the composition is cured through UV or thermal energy. Three-dimensional patterned nanostructures may be formed. A number of patterned nanostructure layers may be prepared and joined together. In some cases, a patterned nanostructure may be formed as a layer that is releasable from the substrate upon which it is initially formed. Such releasable layers may be arranged to form a three-dimensional patterned nanostructure for suitable applications.
FILED Thursday, April 07, 2022
APPL NO 17/715411
ART UNIT 1785 — Miscellaneous Articles, Stock Material
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/118 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/08 (20130101) Original (OR) Class
H01B 3/10 (20130101)
H01B 13/003 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 51/0015 (20130101)
H01L 51/442 (20130101)
H01L 51/5209 (20130101)
H01L 2251/5369 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/04 (20130101)
H01M 4/0433 (20130101)
H01M 6/40 (20130101)
H01M 8/124 (20130101)
H01M 8/1286 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)

Technical Subjects Covered by Former US Classification
Y10T 428/24893 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588226 Shafer et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Arizona Board of Regents acting for and on behalf of Northern Arizona University (Flagstaff, Arizona)
ASSIGNEE(S) Arizona Board of Regents Acting for and on behalf of Northern Arizona University (Flagstaff, Arizona)
INVENTOR(S) Michael W. Shafer (Flagstaff, Arizona);  Paul G. Flikkema (Flagstaff, Arizona)
ABSTRACT Implementations of a method of detecting a plurality of radio pulses may include, using a signal processor, combining at least three pulses included in radio data collected over a first time interval by a directional antenna coupled with a software defined radio coupled with a unmanned aerial vehicle (UAV), the UAV coupled with a base station including the signal processor; determining a detected time for each of the at least three pulses in the first time interval; using the detected time for each of the at least three pulses, predicting a future time for each of at least three future pulses; and, using the software defined radio and directional antenna, listening for each of the at least three future pulses in radio data over a second time interval.
FILED Wednesday, September 22, 2021
APPL NO 17/448511
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 11/008 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 1/045 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/28 (20130101) Original (OR) Class
H01Q 1/273 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588240 Afzal et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Hamidreza Afzal (Davis, California);  Omeed Momeni (Davis, California);  Rouzbeh Kananizadeh (Folsom, California);  Razieh Abedi (Irvine, California);  Payam Heydari (Irvine, California)
ABSTRACT Techniques, systems and architectures for generating desired phase shifts in a phased array to control the directions of radiation in a wide range of angles are disclosed. Particularly, phased array architectures based on novel PLL-coupled phase shifting techniques for implementation in millimeter-wave (mm-wave) and sub-terahertz (sub-THz) operations range are described. In one aspect, a phased array including an array of unit cells is disclosed. In some embodiments, each unit cell in the array of unit cells includes a dual-nested PLL that is configured to effectuate phase locking and frequency locking to a reference signal from an adjacent unit cell. Moreover, each PLL includes control circuitry that can generate a wide range of phase shifts between adjacent unit cells to facilitate phased-array operations. Note that using the dual-nested PLL to generate a desired phase shift between adjacent radiating elements eliminates the use of conventional lossy phase shifters in the phased array.
FILED Thursday, October 07, 2021
APPL NO 17/496626
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 3/36 (20130101) Original (OR) Class

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/0802 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588418 Pint et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Cary L. Pint (Nashville, Tennessee);  Nitin Muralidharan (Nashville, Tennessee)
ABSTRACT Disclosed herein are energy harvesting devices and methods of making and use thereof. The energy harvesting devices can efficiently harvest energy for motions at a frequency of 5 Hz or less.
FILED Wednesday, August 08, 2018
APPL NO 16/058046
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/11 (20130101)
A61B 5/112 (20130101)
A61B 5/4585 (20130101)

Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 7/005 (20130101)
F03G 7/08 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/0906 (20130101)

Electric Machines Not Otherwise Provided for
H02N 2/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588526 Sur et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of South Carolina (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Sanjib Sur (Cayce, South Carolina);  Moh. S. Saadat (West Columbia, South Carolina);  Srihari Nelakuditi (Columbia, South Carolina)
ABSTRACT Described herein are systems, methods and devices for implementing a temperature-aware, multi-antenna scheduler that cools mmWave devices by preventing heat buildup via switching or distributing a data stream to other redundant antennas, allowing for dissipation of heat as well as providing reliable connectivity.
FILED Monday, May 24, 2021
APPL NO 17/327881
ART UNIT 2464 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 7/0608 (20130101) Original (OR) Class
H04B 7/0693 (20130101)

Wireless Communication Networks
H04W 52/0277 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588532 Gupta et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) WASHINGTON STATE UNIVERSITY (Pullman, Washington)
ASSIGNEE(S) WASHINGTON STATE UNIVERSITY (Pullman, Washington)
INVENTOR(S) Subhanshu Gupta (Pullman, Washington);  Erfan Ghaderi (Hillsboro, Oregon)
ABSTRACT An N-element baseband (BB) time-domain spatial signal processor system and methodology for large modulated bandwidth multi-antenna receivers are provided. Such a processor generally includes a pipeline converter configured as an asynchronous time-to-digital converter, wherein the asynchronous time-to-digital converter arrangement generates a residue value and an asynchronous pulse and is further arranged to amplify the residue value so as to result in an amplified residue value; and a 2-bit flash time-to-digital-converter configured to quantize the amplified residue value. Thus, a true-time delay spatial signal processing system and technique in the time-domain that enables beamforming, beam-nulling and multiple independent interference cancellation after time-alignment of signals using cascaded voltage-to-time converters and quantization using relaxed pipeline time-to-digital converters is presented.
FILED Tuesday, May 04, 2021
APPL NO 17/307008
ART UNIT 2632 — Digital Communications
CURRENT CPC
Time-interval Measuring
G04F 10/005 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/36 (20130101)
H01Q 3/2611 (20130101)

Transmission
H04B 7/0639 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 25/03891 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588539 Polese et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Michele Polese (Boston, Massachusetts);  Francesco Restuccia (Boston, Massachusetts);  Tommaso Melodia (Newton, Massachusetts)
ABSTRACT A system and method for beam management in a wireless network are provided. A learning module having a trained classification module processes received I/Q input samples to determine transmitted beam information of incoming RF transmissions. The learning module includes a beam inference engine to determine waveform characteristics of incoming RF transmissions, and an angle of arrival engine operative to determine an angle of arrival of the incoming RF transmissions on an antenna array. An incoming RF transmission and angle of arrival are selected based on the determined waveforms for beam management operations.
FILED Wednesday, September 22, 2021
APPL NO 17/481378
ART UNIT 2631 — Digital Communications
CURRENT CPC
Transmission
H04B 7/086 (20130101) Original (OR) Class
H04B 7/088 (20130101)
H04B 7/0695 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588645 Yavuz
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Attila A. Yavuz (Tampa, Florida)
ABSTRACT A new compromise-resilient and compact cryptographic tool is provided that ensures a breach-resilient authentication and integrity of system measurements in computer systems. The described methods are forward-secure digital signatures with signature and partial public key aggregation capabilities. The methods reduce the total space overhead of signature and public key storage. The methods offer a high space efficiency for systems who has relatively low state transitions, wherein the same message is continuously signed and then followed by different messages.
FILED Wednesday, September 02, 2020
APPL NO 17/009884
ART UNIT 2497 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/14 (20130101)
H04L 9/3073 (20130101)
H04L 9/3247 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588926 Shi
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Justin Yuan Shi (Wayne, Pennsylvania)
ABSTRACT A system for network-scale parallel computing comprises a set of computer-readable instructions implementing the steps of executing a computational process from at least one client node by communicating via a content addressable service network implemented using the Tuple Space abstraction, data parallel semantics and Unidirectional Virtual Ring architecture, with any number of service computers, networks and storage to deliver lossless, non-stop services. A network-scale distributed storage system, an enhanced Domain Name System (DNS) system, a network-scale database system and a network-scale hybrid transactional analytical processing systems are also described.
FILED Tuesday, November 14, 2017
APPL NO 16/348899
ART UNIT 2447 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 69/14 (20130101)
H04L 69/40 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11589286 Liang
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Trustees of Indiana University (Indianapolis, Indiana)
ASSIGNEE(S) The Trustees of Indiana University (Bloomington, Indiana)
INVENTOR(S) Yao Liang (Carmel, Indiana)
ABSTRACT A system and method for data acquisition in a wireless sensor network include receiving measurements made by a plurality of sensor nodes in the wireless sensor network during a given time period, the measurements being carried in data packets that are routed from the plurality of sensor nodes to a base node. The system and method also include determining a plurality of routing paths for the data packets based on routing topology tomography. The system and method further include determining a measurement matrix and a representation basis, and acquiring sensor signals in the wireless sensor network based on the measurement matrix and the representation basis.
FILED Friday, May 08, 2020
APPL NO 16/869742
ART UNIT 2469 — Multiplex and VoIP
CURRENT CPC
Wireless Communication Networks
H04W 4/38 (20180201)
H04W 40/02 (20130101) Original (OR) Class
H04W 84/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11583608 Stasko et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Novan, Inc. (Morrisville, North Carolina)
ASSIGNEE(S) Novan, Inc. (Durham, North Carolina)
INVENTOR(S) Nathan Stasko (Chapel Hill, North Carolina);  Susanne Bauman (Durham, North Carolina);  Pranav R. Joshi (Bangalore, India)
ABSTRACT Provided according to some embodiments of the invention are wound dressings that include a polymer matrix and nitric oxide-releasing polysiloxane macromolecules within and/or on the polymer matrix. Also provided are wound dressing kits and methods of using and forming such wound dressings.
FILED Friday, February 02, 2018
APPL NO 15/887649
ART UNIT 3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/44 (20130101) Original (OR) Class
A61L 15/225 (20130101)
A61L 15/225 (20130101)
A61L 15/225 (20130101)
A61L 15/425 (20130101)
A61L 2300/45 (20130101)
A61L 2300/114 (20130101)
A61L 2300/602 (20130101)

Compositions of Macromolecular Compounds
C08L 75/04 (20130101)
C08L 83/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11583814 Bromberg et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) MAAT Energy Company (Cambridge, Massachusetts)
ASSIGNEE(S) MAAT Energy Company (Cambridge, Massachusetts)
INVENTOR(S) Leslie Bromberg (Sharon, Massachusetts);  Kim-Chinh Tran (Cambridge, Massachusetts);  Jorj Ian Owen (Dulles, Virginia);  Jonathan Whitlow (Melbourne Beach, Florida)
ABSTRACT Devices and methods for reducing the specific energy required to reform or pyrolyze reactants in plasmas operating at high flow rates and high pressures are presented. These systems and methods include 1) introducing electrons and/or easily ionized materials to a plasma reactor, 2) increasing turbulence and swirl velocity of the flows of feed gases to have improved mixing in a plasma reactor, and 3) reducing slippage from a plasma reactor system. Such plasma systems may allow plasma reactors to operate at lower temperatures, higher pressure, with improved plasma ignition, increased throughput and improved energy efficiency. In preferred embodiments, the plasma reactors are used to produce hydrogen and carbon monoxide, hydrogen and carbon, or carbon monoxide through reforming and pyrolysis reactions. Preferred feedstocks include methane, carbon dioxide, and other hydrocarbons.
FILED Tuesday, February 25, 2020
APPL NO 17/433131
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 4/001 (20130101)
B01J 6/008 (20130101) Original (OR) Class
B01J 8/0278 (20130101)
B01J 19/088 (20130101)
B01J 19/126 (20130101)
B01J 19/129 (20130101)
B01J 19/2405 (20130101)
B01J 2219/00159 (20130101)
B01J 2219/0847 (20130101)
B01J 2219/0849 (20130101)
B01J 2219/0892 (20130101)
B01J 2219/0898 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/26 (20130101)
C01B 3/382 (20130101)
C01B 2203/0205 (20130101)
C01B 2203/0277 (20130101)
C01B 2203/0861 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11584957 Mitra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Lucira Health, Inc. (Emeryville, California)
ASSIGNEE(S) Lucira Health, Inc. (Emeryville, California)
INVENTOR(S) Debkishore Mitra (Berkeley, California);  Ivan Krastev Dimov (Union City, California);  John Robert Waldeisen (Berkeley, California)
ABSTRACT Colorimetry is used to detect amplification reaction products. A sample is contacted with a reaction mix under conditions such that an amplification reaction occurs and produces an amplification reaction product if the sample contains a target nucleic acid template molecule. The reaction mix includes an enzyme for catalyzing the amplification reaction, and at least one halochromic agent. If the target nucleic acid template molecule is present, the amplification reaction changes the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating the presence of the target nucleic acid. If the target nucleic acid template molecule is not present, the amplification reaction does not generate an adequate number of protons to sufficiently change the starting pH of the reaction mix to cause a detectable colorimetric change of the halochromic agent, thereby indicating that the amplification reaction product has not been produced.
FILED Friday, June 05, 2020
APPL NO 16/894694
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6844 (20130101) Original (OR) Class
C12Q 1/6846 (20130101)
C12Q 1/6846 (20130101)
C12Q 2527/119 (20130101)
C12Q 2527/125 (20130101)
C12Q 2563/173 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586968 King et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Atom Computing Inc. (Berkeley, California)
ASSIGNEE(S) ATOM COMPUTING INC. (Berkeley, California)
INVENTOR(S) Jonathan King (Berkeley, California);  Benjamin Bloom (Berkeley, California);  Krish Kotru (Berkeley, California);  Brian Lester (Berkeley, California);  Maxwell Parsons (Berkeley, California)
ABSTRACT The present disclosure provides methods and systems for performing non-classical computations. The methods and systems generally use a plurality of spatially distinct optical trapping sites to trap a plurality of atoms, one or more electromagnetic delivery units to apply electromagnetic energy to one or more atoms of the plurality to induce the atoms to adopt one or more superposition states of a first atomic state and a second atomic state, one or more entanglement units to quantum mechanically entangle at least a subset of the one or more atoms in the one or more superposition states with at least another atom of the plurality, and one or more readout optical units to perform measurements of the superposition states to obtain the non-classical computation.
FILED Wednesday, November 06, 2019
APPL NO 16/676317
ART UNIT 2872 — Optics
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587232 Wick et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) CAMERAD TECHNOLOGIES (Decatur, Georgia);  THE UAB RESEARCH FOUNDATION (Birmingham, Alabama)
ASSIGNEE(S) CAMERAD TECHNOLOGIES (Decatur, Georgia);  THE UAB RESEARCH FOUNDATION (Birmingham, Alabama)
INVENTOR(S) Carson Arthur Wick (Atlanta, Georgia);  Srini Tridandapani (Decatur, Georgia)
ABSTRACT A method for preventing wrong-patient errors includes receiving a selection of a current imaging subject. The current imaging subject is selected for a current image acquisition session comprising capturing one or more current images of the current imaging subject utilizing at least a first image sensor system of a first imaging modality. The method includes accessing one or more previous images of a previous imaging subject. The one or more previous images depict the previous imaging subject according to at least a second imaging modality that is different from the first imaging modality. The method includes presenting the one or more previous images on a display system and, in response to determining that the previous imaging subject matches the current imaging subject based upon the one or more previous images, performing the current image acquisition session.
FILED Friday, May 06, 2022
APPL NO 17/738932
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0035 (20130101)

Electric Digital Data Processing
G06F 3/165 (20130101)

Image Data Processing or Generation, in General
G06T 7/0016 (20130101) Original (OR) Class
G06T 2200/24 (20130101)
G06T 2207/10016 (20130101)
G06T 2207/30004 (20130101)

Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 17/04 (20130101)
G10L 17/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11587682 Longmire et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Medable Inc. (Palo Alto, California)
ASSIGNEE(S) Medable Inc. (Palo Alto, California)
INVENTOR(S) Michelle Longmire (Palo Alto, California);  Ingrid Oakley-Girvan (Henderson, California);  Nick Moss (Los Alamos, New Mexico)
ABSTRACT A method and system for connecting, capturing, managing and predicting outcomes for an improved care for home based patients by collecting data from caregivers and home-based patients. The method and system implemented as a mobile technology is more efficient and effective method for delivering healthcare that will ease the caregiving burden. Providing resources and information to communicate, capture and deliver by the caregivers (formal and informal), patients and healthcare providers communicate helps integrate essential data and care. Through the use of this mobile technology and associated devices vital information from informal caregivers, which is currently not regularly used in remotely located patients, can be captured and implemented in the decisions and adjustments to patients' care plans. In addition, the technology helps with adherence of patient specific treatment guidelines for home-based patients.
FILED Sunday, March 14, 2021
APPL NO 17/200866
ART UNIT 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/20 (20180101)
G16H 10/65 (20180101)
G16H 50/20 (20180101) Original (OR) Class
G16H 80/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588176 Lin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Bioenno Tech LLC (Santa Ana, California)
ASSIGNEE(S) Bioenno Tech LLC (Santa Ana, California)
INVENTOR(S) Zhigang Lin (Santa Ana, California);  Chunhu Tan (Santa Ana, California);  Tianyu Meng (Santa Ana, California)
ABSTRACT Electrolyte-infiltrated composite electrode includes an electrolyte component consisting of a polymer matrix with ceramic nanoparticles embedded in the matrix to form a networking structure of electrolyte. Suitable ceramic nanoparticles have the basic formula Li7La3Zr2O12 (LLZO) and its derivatives such as AlxLi7-xLa3Zr2-y-zTayNbzO12 where x ranges from 0 to 0.85, y ranges from 0 to 0.50 and z ranges from 0 to 0.75, wherein at least one of x, y and z is not equal to 0. The networking structure of the electrolyte establishes an effective lithium-ion transport pathway in the electrode and strengthens the contact between electrode layer and solid-state electrolyte resulting in higher lithium-ion electrochemical cell's cycling stability and longer battery life. Sold-state electrolytes incorporating the ceramic particles demonstrate improved performance. Large dimensional electrolyte-infiltrated composite electrode sheets can be used in all solid-state lithium electrochemical pouch cells which can be assembled into battery packs.
FILED Monday, January 04, 2021
APPL NO 17/140690
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/622 (20130101)
H01M 4/625 (20130101)
H01M 10/0525 (20130101)
H01M 10/0562 (20130101) Original (OR) Class
H01M 2004/021 (20130101)
H01M 2300/0071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11582956 Zhu et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-ST)
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) James J. Zhu (Niantic, Connecticut);  Elizabeth A. Bishop (Shelter Island, New York);  Palaniappan Ramanathan (Dickinson, Texas)
ABSTRACT Disclosed herein is a recombinant adenovirus genome, said adenovirus genome comprising a heterologous nucleic acid inserted into a cloning site of said genome, said heterologous nucleic acid comprising: (a) a first nucleic acid sequence comprising an adenovirus tripartite sequence (e.g., SEQ ID NO:1) operably linked to a second nucleic acid sequence encoding an interferon (e.g., SEQ ID NO:2); (b) a third nucleic acid sequence comprising a bovine growth hormone polyA termination sequence operably linked to said second nucleic acid sequence (e.g., SEQ ID NO:3); (c) a fourth nucleic acid sequence comprising a porcine elongation factor 1-alpha (EF1α) promoter (e.g., SEQ ID NO:4); (d) a fifth nucleic acid sequence operably linked to said fourth nucleic acid sequence, said fifth nucleic acid sequence encoding a suppressor of cytokine signaling 1 (SOCS1) protein (e.g., SEQ ID NO:5). Furthermore, there is disclosed a method of producing interferon in an animal (e.g., swine).
FILED Tuesday, September 03, 2019
APPL NO 16/558501
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101) Original (OR) Class
A01K 2207/15 (20130101)
A01K 2217/15 (20130101)
A01K 2217/056 (20130101)
A01K 2217/072 (20130101)
A01K 2217/206 (20130101)
A01K 2227/108 (20130101)
A01K 2267/01 (20130101)

Peptides
C07K 14/52 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 15/907 (20130101)
C12N 2015/8518 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11582968 West et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S) North Carolina State University (Raleigh, North Carolina)
INVENTOR(S) Andre J. West (Raleigh, North Carolina);  Marian G. McCord (Raleigh, North Carolina);  Richard Michael Roe (Raleigh, North Carolina);  James Brian Davis (Raleigh, North Carolina);  Jiwei Zhu (Raleigh, North Carolina)
ABSTRACT A variety of agricultural spacer fabrics/textiles are provided that protect plants from insect penetration while allowing for light and air penetration, and methods of use. The textiles can be used alone or in conjunction with agents such as insecticides, insect repellants, and fungicides. The agricultural textile can have an outermost fabric layer, an innermost fabric layer, and a plurality of filaments connecting the outermost fabric layer and the innermost fabric layer.
FILED Saturday, January 26, 2019
APPL NO 16/258574
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 25/24 (20130101)
A01N 25/34 (20130101) Original (OR) Class
A01N 25/34 (20130101)
A01N 31/02 (20130101)
A01N 49/00 (20130101)
A01N 53/00 (20130101)
A01N 53/00 (20130101)

Knitting
D04B 21/16 (20130101)
D04B 21/20 (20130101)

Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials
D06M 13/144 (20130101)
D06M 13/2246 (20130101)

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2403/033 (20130101)
D10B 2505/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11582990 Aksoy et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) Auburn University (Auburn, Alabama);  The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) Auburn University (Auburn, Alabama);  The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Burak Aksoy (Auburn, Alabama);  Zhihua Jiang (Auburn, Alabama);  Mediha Aksoy (Auburn, Alabama);  Benjamin Beck (Auburn, Alabama)
ABSTRACT A method of making a binder for extruded, pelleted, or agglomerated animal feed. The binder is made by treating biomass such as soybean hull or lemon peels with an aqueous acidic solution for a time, at a temperature, and at a pH sufficient to yield a first mixture containing biomass solids and partially dissolved biomass; and mechanically treating the first mixture of step to yield a first mechanically treated mixture; and then incorporating the first mechanically treated mixture as a binder in an animal feed. Also described are animal feeds made using the binder.
FILED Friday, January 17, 2020
APPL NO 16/745562
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Fodder
A23K 10/30 (20160501)
A23K 20/147 (20160501)
A23K 20/163 (20160501)
A23K 40/10 (20160501)
A23K 40/25 (20160501) Original (OR) Class
A23K 50/80 (20160501)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11585291 Muldoon et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Neil A Armstrong Flight Research Center (AFRC)
APPLICANT(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Marc J. Muldoon (East Hartford, Connecticut);  Jonathan Rheaume (East Hartford, Connecticut);  Stephen H. Taylor (East Hartford, Connecticut)
ABSTRACT An ejector assembly for a cooling system of a gas turbine engine may comprise: a tail cone having a tail cone outlet in fluid communication with a cooling air flow of the cooling system; an ejector body defining a mixing section, a constant area section, and a diffuser section; and a nozzle section in fluid communication with an exhaust air flow of the gas turbine engine, the ejector assembly configured to entrain the cooling air flow via the exhaust air flow.
FILED Friday, September 11, 2020
APPL NO 17/018795
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 15/10 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/18 (20130101)
F02C 7/32 (20130101)

Jet-propulsion Plants
F02K 1/36 (20130101) Original (OR) Class
F02K 1/38 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2220/76 (20130101)
F05D 2260/201 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11586497 Geist et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Alessandro Geist (Bethesda, Maryland);  Cody Brewer (Greenbelt, Maryland);  Robin A. Ripley (Greenbelt, Maryland);  Christopher M. Wilson (Greenbelt, Maryland);  Nicholas Franconi (Greenbelt, Maryland);  Gary A. Crum (Silver Spring, Maryland);  David J. Petrick (Severna Park, Maryland);  Thomas P. Flatley (Huntingtown, Maryland)
ABSTRACT The present invention relates to a single-board processor card configured for use in a 1U CubeSat payload form-factor multi-purpose architecture, including: a field-programmable-gate-array (FPGA) which is reconfigurable in flight; wherein a configuration memory of the FPGA can be scrubbed in flight to correct errors or upsets; and a radiation-hardened monitor (RHM) which provides radiation mitigation and system monitoring of the single-board processor card, and which reconfigures said FPGA during flight, scrubs the configuration memory, and monitors a health of the FPGA. The 1U CubeSat payload form-factor multi-purpose architecture includes a backplane having a plurality of slots, one of the plurality of slots which accommodates the single-board processor card, wherein the backplane routes signals to a plurality of standard-sized processor cards, interchangeably disposed in any of the plurality of slots.
FILED Thursday, September 17, 2020
APPL NO 17/023513
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/106 (20130101) Original (OR) Class
G06F 11/1629 (20130101)
G06F 30/34 (20200101)

Coding; Decoding; Code Conversion in General
H03M 13/19 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588628 Wroblewski
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Adam C. Wroblewski (Cleveland, Ohio)
ABSTRACT A space and wave division multiplexing and demultiplexing system and method for quantum key distribution (QKD) using free space laser communications. The system operates to transmit a quantum channel, including a key of QKD, included in a combined laser transmission with a classical channel, including an encrypted message of QKD. The laser transmission can be transmitted through free space to a lens, wherein it is diffracted into two separate diffraction patterns and captured by a double clad optical receiver fiber having an inner core and a concentric outer core. The diffraction pattern of the classical channel is captured by the outer core, while the diffraction pattern of the quantum channel is captured by the inner core, thus allowing separate treatment of each channel.
FILED Wednesday, March 31, 2021
APPL NO 17/218788
ART UNIT 2437 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/083 (20130101)
H04L 9/085 (20130101)
H04L 9/0858 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11582956 Zhu et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-ST)
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) James J. Zhu (Niantic, Connecticut);  Elizabeth A. Bishop (Shelter Island, New York);  Palaniappan Ramanathan (Dickinson, Texas)
ABSTRACT Disclosed herein is a recombinant adenovirus genome, said adenovirus genome comprising a heterologous nucleic acid inserted into a cloning site of said genome, said heterologous nucleic acid comprising: (a) a first nucleic acid sequence comprising an adenovirus tripartite sequence (e.g., SEQ ID NO:1) operably linked to a second nucleic acid sequence encoding an interferon (e.g., SEQ ID NO:2); (b) a third nucleic acid sequence comprising a bovine growth hormone polyA termination sequence operably linked to said second nucleic acid sequence (e.g., SEQ ID NO:3); (c) a fourth nucleic acid sequence comprising a porcine elongation factor 1-alpha (EF1α) promoter (e.g., SEQ ID NO:4); (d) a fifth nucleic acid sequence operably linked to said fourth nucleic acid sequence, said fifth nucleic acid sequence encoding a suppressor of cytokine signaling 1 (SOCS1) protein (e.g., SEQ ID NO:5). Furthermore, there is disclosed a method of producing interferon in an animal (e.g., swine).
FILED Tuesday, September 03, 2019
APPL NO 16/558501
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101) Original (OR) Class
A01K 2207/15 (20130101)
A01K 2217/15 (20130101)
A01K 2217/056 (20130101)
A01K 2217/072 (20130101)
A01K 2217/206 (20130101)
A01K 2227/108 (20130101)
A01K 2267/01 (20130101)

Peptides
C07K 14/52 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 15/907 (20130101)
C12N 2015/8518 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585801 Latham
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-ST)
APPLICANT(S) The MITRE Corporation (McLean, Virginia)
ASSIGNEE(S) The MITRE Corporation (McLean, Virginia)
INVENTOR(S) Robert Latham (Springfield, Virginia)
ABSTRACT Method, systems, and techniques for determining the age of an underground space are provided. In some embodiments, determining the age of an underground space comprises taking soil samples from a plurality of surface locations within a second underground space, analyzing the soil samples from the plurality of surface locations to determine an amount of a chemical compound for each soil sample, and determining an age of the second underground space using one or more relationships based on amounts of the chemical compound measured in a plurality of soil samples taken over a period of time in a first underground space and a baseline amount of the chemical compound at one or more locations remote from both the first underground space and the second underground space.
FILED Friday, June 26, 2020
APPL NO 16/913762
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/79 (20130101)
G01N 21/3563 (20130101)
G01N 23/223 (20130101)
G01N 23/2076 (20130101)
G01N 33/24 (20130101) Original (OR) Class
G01N 2021/3572 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11588091 Hussein et al.
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado);  Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland);  The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) Mahmoud Hussein (Boulder, Colorado);  Kristine A. Bertness (Boulder, Colorado);  Howard Branz (Boulder, Colorado);  Joel C. Weber (Boulder, Colorado)
ABSTRACT A nanophononic metamaterial-based thermoelectric energy conversion device and processes for fabricating a nanophononic metamaterial-based thermoelectric energy conversion device is provided. In one implementation, for example, a nanophononic metamaterial-based thermoelectric energy conversion device includes a first conductive pad, a second conductive pad, and a plurality of strip units. In one implementation, the first conductive pad is coupled to a first connection of the thermoelectric energy conversion device, and the second conductive pad is coupled to a second connection of the thermoelectric energy conversion device. The plurality of strip units are connected in series between the first and second conductive pads and provide a parallel heat transfer pathway. The strip units include a nanostructure design comprising a nanophononic metamaterial.
FILED Saturday, February 09, 2019
APPL NO 16/271823
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 21/02 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/10 (20130101)
H01L 35/14 (20130101) Original (OR) Class
H01L 35/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11583626 Vidovich
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) The Board of Trustees of the University of Illinois (Chicago, Illinois);  The US Government Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  The US Government Represented by the Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) Mladen I. Vidovich (Chicago, Illinois)
ABSTRACT The present invention is directed to a multi-angulated catheter and methods of using the multi-angulated catheter. The multi-angulated catheter is so dimensioned as to facilitate accessing the left ventricle from an arm of a patient. The multi-angulated catheter generally includes in order: (a) a coiled end; (b) a first straight portion having a first straight portion length; (c) a first shaft including a distal end connected to the first straight portion and a proximal end opposite the distal end, the first shaft and the first straight portion defining a first obtuse angle, the first shaft having a first shaft length; and (d) a second shaft connected to the first shaft on said proximal end. The catheter is flexible so as to afford being straightened when it is advanced over a guide wire. The catheter resiliently returns to a multi-angulated position after the guide wire is withdrawn.
FILED Monday, November 04, 2019
APPL NO 16/673186
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/007 (20130101) Original (OR) Class
A61M 25/0041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11588798 Cline et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) The Government of the United States as represented by the Director, National Security Agency (Ft. George G. Meade, Maryland)
ASSIGNEE(S) Government of the United States, as represented by the National Security Agency (, None)
INVENTOR(S) Joshua E. Cline (Edgewater, Maryland);  Dan A. DeVries (Brooklyn, Maryland);  William J. Layton (Sykesville, Maryland);  Zachary Smith (Severn, Maryland);  Brendan S. Surrusco (Highland, Maryland);  Andrew H. White (Catonsville, Maryland);  David F. Wiecek (Ft. George G. Meade, Maryland);  Mitchell E. Buchman (Hanover, Maryland)
ABSTRACT The present invention provides an encrypting device including an encryption unit and a communications unit. Paired encrypting devices allow for communication of trusted data between trusted devices over an untrusted network. Data received by the encryption unit is encrypted and provided with a connectionless header for delivery to the communications unit. Data received by the communications units is provided with a complex header for delivery to the paired encrypting device. The encrypting devices may be implemented in hardware or may be virtualized on a server or a plurality of servers. Arrangement of the encrypting devices in a hub-and-spoke topology allows for communication amongst a plurality of trusted devices. The encrypting devices can be used to convert commercially available equipment suitable for high assurance environments.
FILED Friday, March 12, 2021
APPL NO 17/200468
ART UNIT 2499 — Multiplex and VoIP
CURRENT CPC
Electric Digital Data Processing
G06F 21/602 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 45/74 (20130101)
H04L 63/0272 (20130101)
H04L 63/0471 (20130101) Original (OR) Class

Wireless Communication Networks
H04W 28/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11583528 Smith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Child Health and Human Development (NICHD)
Non-Profit Organization (NPO)
Bright Focus Foundation
Massachusetts Lions Eye Research Fund, Inc.
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Lois Smith (West Newton, Massachusetts);  Jean-Sebastien Joyal (Boston, Massachusetts)
ABSTRACT The instant invention provides methods and compositions related to discovery of Free Fatty Acid Receptor 1 (FFA1) as a therapeutic target for treatment or prevention of diseases or disorders of neurons that are characterized by angiogenesis, or of vascular diseases of the eye, retinal degeneration and/or tumors more generally. Therapeutic and/or prophylactic uses and compositions of known FFA1 inhibitors, including small molecules and nucleic acid agents, are described. Methods for identification of novel FFA1 inhibitors are also provided.
FILED Friday, February 17, 2017
APPL NO 15/999535
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/352 (20130101)
A61K 31/513 (20130101) Original (OR) Class
A61K 31/519 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5044 (20130101)
G01N 2800/50 (20130101)
G01N 2800/164 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 11586884 Yang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) University of Massachusetts (Amherst, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Jianhua Yang (Hadley, Massachusetts);  Qiangfei Xia (Amherst, Massachusetts);  Mark McLean (Severna Park, Maryland);  Qing Wu (Manilus, New York)
ABSTRACT A diffusive memristor device and an electronic device for emulating a biological neuron is disclosed. The diffusive memristor device includes a bottom electrode, a top electrode formed opposite the bottom electrode, and a dielectric layer disposed between the top electrode and the bottom electrode. The dielectric layer comprises an oxide doped with a metal.
FILED Friday, February 08, 2019
APPL NO 16/270848
ART UNIT 2123 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/061 (20130101)
G06N 3/063 (20130101) Original (OR) Class
G06N 3/0454 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11587016 Briggman et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) Chandra A. Briggman (Springfield, Virginia);  Jane Elizabeth Quenk (Washington, District of Columbia);  Timothy M. Moran (National Harbor, Maryland);  Kelley A. Sullivan (Alexandria, Virginia);  Robert E. Dixon, Jr. (Washinton, District of Columbia)
ABSTRACT A method, electronic device, and computer-readable storage medium are provided. In one embodiment, a method is provided for receiving a request to display a calendar associated with a delivery point of a user, accessing shipment information associated with the user, the shipment information including a record of physical delivery items and electronic delivery items, and displaying, for each day on the calendar, a count of the physical delivery items and electronic delivery items.
FILED Monday, June 17, 2019
APPL NO 16/443154
ART UNIT 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)
G06Q 10/083 (20130101)
G06Q 10/0833 (20130101) Original (OR) Class
G06Q 10/1093 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 51/42 (20220501)
H04L 51/214 (20220501)
H04L 51/234 (20220501)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11583689 Kim et al.
FUNDED BY
APPLICANT(S) AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Suwon-si, South Korea)
ASSIGNEE(S) AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Suwon-si, South Korea)
INVENTOR(S) Chul Ho Kim (Seoul, South Korea);  Yun Sang Lee (Seoul, South Korea);  Myeong Hoon Lee (Suwon-si, South Korea)
ABSTRACT The present invention relates to a composition for atopy or psoriasis treatment comprising a plasma-treated liquid material. More particularly, the present invention relates to a method for producing a plasma-treated liquid material for preventing or treating atopic dermatitis or psoriasis, a pharmaceutical composition for preventing or treating a topic dermatitis or psoriasis using a plasma-treated liquid material produced according to the method, and a method for preventing or treating atopic dermatitis or psoriasis using the plasma-treated liquid material.
FILED Tuesday, September 19, 2017
APPL NO 16/335904
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/44 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 37/32082 (20130101)
H01J 37/32825 (20130101)
H01J 2237/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11585274 Anderson et al.
FUNDED BY
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) William C. Anderson (Evendale, Ohio);  Thomas E. Agin (Evendale, Ohio);  Michael William Murrish (Evendale, Ohio);  Timothy McCann (Cincinnati, Ohio);  Caitlin Ford (Cincinnati, Ohio)
ABSTRACT A turbofan engine includes an outer bypass duct and a gas turbine engine having an outer casing. The gas turbine engine is disposed in the outer bypass duct such that a bypass airflow passage is formed between the outer casing of the gas turbine engine and the outer bypass duct. The turbofan engine includes a turbine rear frame link assembly including a set of links coupled between the outer bypass duct and the outer casing to support the gas turbine engine relative to the outer bypass duct. The links are arranged around the gas turbine engine on a plane that is perpendicular to a centerline axis of the turbofan engine. None of the links extends through the bypass airflow passage at a position that intersects a radius extending in a vertically downward direction from the centerline axis.
FILED Monday, December 28, 2020
APPL NO 17/135640
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 25/28 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/20 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11588482 Tsen et al.
FUNDED BY
APPLICANT(S) HRL Laboratories, LLC (Malibu, California)
ASSIGNEE(S) HRL LABORATORIES, LLC (Malibu, California)
INVENTOR(S) Chan-Tang Tsen (Thousand Oaks, California);  Donald Hitko (Olney, Maryland);  Susan Morton (Pittsford, New York)
ABSTRACT A signal processing circuit. In some embodiments, the signal processing circuit includes a first sample and hold circuit and a second sample and hold circuit. The first sample and hold circuit may include: a hold capacitor; an input switch connected between a common input node and the hold capacitor; a signal path amplifier having an input connected to the hold capacitor; and an output switch connected between an output of the signal path amplifier and a common output node. An input of a voltage feedback amplifier may be connected to the hold capacitor, and an output of the voltage feedback amplifier may be operatively coupled to an internal node of the input switch.
FILED Monday, November 01, 2021
APPL NO 17/516582
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Amplifiers
H03F 3/45475 (20130101)

Pulse Technique
H03K 17/6871 (20130101) Original (OR) Class
H03K 19/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11589248 Greenberg et al.
FUNDED BY
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Adam Hodge Greenberg (Los Angeles, California);  Richard A. Loveless (Redondo Beach, California)
ABSTRACT A method for identifying a current state of an electronic system is provided. The method includes identifying a pool of candidate states of the electronic system, selecting a probing parameter in accordance with a model, and probing the electronic system based on the selected probing parameter. When the probing yields a positive result, all candidate states that are not intersected by the probing parameter are removed from the pool. When the probing parameter yields M negative results, all candidate states that are intersected by the probing parameter are removed from the pool, where M≥1. A last remaining candidate state in the pool is identified as the current state of the electronic system. The model is based on at least one of a probability that the probing would yield a false-negative result or a probability that a result of the probing would be interpreted and/or processed incorrectly.
FILED Thursday, February 18, 2021
APPL NO 17/178369
ART UNIT 2412 — Multiplex and VoIP
CURRENT CPC
Wireless Communication Networks
H04W 24/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, February 21, 2023.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230221.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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