FedInvent™ Patents
Patent Details for Tuesday, March 28, 2023
This page was updated on Tuesday, March 28, 2023 at 11:44 AM GMT
Department of Health and Human Services (HHS)
| US 11612163 | Sandlin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Rebecca Sandlin (Charlestown, Massachusetts); Keith Wong (Newton, Massachusetts); Shannon Tessier (Framingham, Massachusetts); Mehmet Toner (Charlestown, Massachusetts); Shannon Stott (Stoneham, Massachusetts) |
| ABSTRACT | Methods for stabilizing blood samples, e.g., clinical blood samples, for storage or transportation before use. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/937528 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Original (OR) Class A01N 1/0231 (20130101) A01N 1/0278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612311 | Senaras et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Caglar Senaras (Eindhoven, Netherlands); Aaron Christopher Moberly (Columbus, Ohio); Theodoros Teknos (Powell, Ohio); Garth Fredric Essig, Jr. (Columbus, Ohio); Charles Albert Elmaraghy (Dublin, Ohio); Nazhat Fatima Taj-Schaal (Lewis Center, Ohio); Lianbo Yu (Columbus, Ohio); Metin Nafi Gurcan (Winston-Salem, North Carolina) |
| ABSTRACT | Disclosed herein are systems and methods to detect a wide range of eardrum abnormalities by using high-resolution otoscope images and report the condition of the eardrum as “normal” or “abnormal.” |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/188681 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/000094 (20220201) A61B 1/227 (20130101) Original (OR) Class A61B 5/12 (20130101) A61B 5/7264 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/0014 (20130101) G06T 2207/10024 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612322 | Stern et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Emily Stern (Chestnut Hill, Massachusetts); David Silbersweig (Chestnut Hill, Massachusetts); Hong Pan (Boston, Massachusetts) |
| ABSTRACT | An automated system and method is provided for biotype extraction and biomarker discovery from task-based fMRI imaging data. The system and method may include automatically mapping a localizome, such as a task-condition/contrast/population-specific brain functional localizome, based on fMRI data and automatically selecting and sorting brain regions or brain nodes to produce a subset of functional brain regions or brain nodes. A report may then be generated indicating that the subject has a particular brain circuit pattern of activity and connectivity associated with one or more symptoms of the given mental disorder, treatments, or associated with normal brain functions, based upon the extracted biosignatures by searching for the optimal multivariate classifier with least dimensionality in the brain functional localizome. These biosignatures and biomarkers that reveal hidden, implicit, and latent brain circuit patterns provoked by fMRI tasks, can also provide for the development of non-invasive diagnostics and targeted therapeutics in neuropsychiatric diseases. |
| FILED | Wednesday, October 03, 2018 |
| APPL NO | 16/753020 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/16 (20130101) A61B 5/0042 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 5/4884 (20130101) A61B 2576/026 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/5608 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 50/70 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612336 | Halpern et al. |
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| FUNDED BY |
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| APPLICANT(S) | Howard J. Halpern (Chicago, Illinois); Boris Epel (Chicago, Illinois) |
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| INVENTOR(S) | Howard J. Halpern (Chicago, Illinois); Boris Epel (Chicago, Illinois) |
| ABSTRACT | An apparatus and method for improved S/N measurements useful for electron paramagnetic resonance imaging in situ and in vivo, using high-isolation transmit/receive surface coils and temporally spaced pulses of RF energy (e.g., in some embodiments, a RF pi pulse) having an amplitude sufficient to rotate the magnetization by 180 degrees followed after varied delays, by a second RF pulse having an amplitude half that of the initial pulse to rotate the magnetization by, e.g., 90 degrees (a pi/2 pulse), to the plane orthogonal to the static field where it evolves for a short time. Then a third RF pi pulse sufficient to rotate the magnetization by, e.g., 180 degrees, forms an echo (in some embodiments, the second and third pulses are from the same signal as the first pulse but are phase shifted by 0, 90, 180, or 270 degrees to reduce signal artifact), to image human body. |
| FILED | Tuesday, July 19, 2016 |
| APPL NO | 15/213768 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/60 (20130101) G01R 33/341 (20130101) G01R 33/3607 (20130101) G01R 33/3621 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612344 | Clements et al. |
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| FUNDED BY |
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| APPLICANT(S) | BioCircuit Technologies, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | BioCircuit Technologies, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Isaac Perry Clements (Marietta, Georgia); Anna Harrison (Atlanta, Georgia); Edgar Brown (Decatur, Georgia); Amanda Preyer (Atlanta, Georgia); James David Ross (Decatur, Georgia); Andrew Willsie (Lilburn, Georgia); Maximilian Sonntag (Atlanta, Georgia) |
| ABSTRACT | Systems, devices, and methods for interfacing with biological tissue are described herein. An example electrode patch as described herein includes a flexible substrate and an electrode array arranged on the flexible substrate. The electrode array includes a plurality of electrodes, where each of the plurality of electrodes is formed of a hydrogel. Additionally, each of the plurality of electrodes defines a raised geometry. Additionally, an example system includes the electrode patch, which is configured to interface with a subject's skin, and an electronics module operably coupled to the electrode array. |
| FILED | Monday, November 04, 2019 |
| APPL NO | 16/673734 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) Original (OR) Class A61B 5/0536 (20130101) A61B 5/6833 (20130101) A61B 5/6843 (20130101) A61B 5/7203 (20130101) A61B 2562/046 (20130101) A61B 2562/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612379 | Dixon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rivanna Medical LLC (Charlottesville, Virginia) |
| ASSIGNEE(S) | Rivanna Medical, Inc. (Charlottesville, Virginia) |
| INVENTOR(S) | Adam Dixon (Charlottesville, Virginia); Frank William Mauldin (Charlottesville, Virginia); Kevin Owen (Crozet, Virginia) |
| ABSTRACT | An ultrasound imaging scan head includes a fluid chamber including a gearless voice-coil motor therein. The voice-coil motor mechanism includes a rigid mechanical assembly, capable of moving with the fluid chamber, having one or more transducer elements and motor windings. Within the fluid chamber are motor magnets physically separated from the rigid mechanical assembly. The ultrasound imaging scan head further includes an inductive position sensor and internal bladder wherein the one or more transducer elements are capable of moving within the fluid chamber when a current is passed through the motor windings in a presence of a magnetic field generated by the one or more motor magnets. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/032382 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/483 (20130101) A61B 8/4461 (20130101) Original (OR) Class A61B 8/5207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612399 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the Stevens Institute of Technology (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Xiaojun Yu (Fishers, Indiana); Munish B. Shah (Galloway, New Jersey); Wei Chang (New York, New York) |
| ABSTRACT | A nerve guidance conduit includes one or more guidance channels formed as porous polymeric structures. The guidance channels are within an outer tubular structure that includes randomly-oriented nanofibers. The guidance channels may have electrospun nanofibers on their inner and outer surfaces in a parallel alignment with the guidance channels. Such aligned nanofibers may also be present on the inner surface of the outer tubular structure. The outer surfaces of the guidance channels and the inner surface of the tubular structure define additional guidance channels. Such a nerve guidance conduit provides augmented surface areas for providing directional guidance and enhancing peripheral nerve regeneration. The structure also has the mechanical and nutrient transport requirements required over long regeneration periods. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/448550 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1128 (20130101) Original (OR) Class A61B 2017/00526 (20130101) A61B 2017/1132 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/50 (20130101) A61L 27/56 (20130101) A61L 2400/12 (20130101) A61L 2430/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612570 | Woodworth et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Graeme F. Woodworth (Baltimore, Maryland); Jeffrey A. Winkles (Frederick, Maryland); Anthony J. Kim (Clarksville, Maryland); Aniket Wadajkar (Germantown, Maryland) |
| ABSTRACT | Metastatic triple negative breast cancer (TNBC) still carries a dismal prognosis with the current treatment paradigms. The effectiveness of drug treatment for many solid tumors such as TNBC is limited by tumor heterogeneity, lack of tumor specificity, off-target toxicities, and transient therapeutic action(s). Strategies that provide tumor-specific, sustained concentrations of drugs to the tumors and tumor receptor-specific binding, while reducing off-target effects are needed to ensure sufficient tumor cell uptake within the primary and metastatic tumor microenvironment. The decreased non-specific adhesivity, receptor-targeted nanoparticle formulations (“DART” nanoparticles) of the invention were assessed for clinical potential in directing biological agents to the cell surface receptor Fn14, which is expressed in many solid cancer types, including TNBC primary tumors and metastatic lesions. They are contemplated for use against solid tumors, particularly brain tumors such as glioblastoma and breast cancer, including metastatic breast cancer. |
| FILED | Monday, October 19, 2020 |
| APPL NO | 16/949198 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) Original (OR) Class A61K 9/5031 (20130101) A61K 31/337 (20130101) A61K 47/60 (20170801) A61K 47/6855 (20170801) A61K 47/6921 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2875 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612580 | Hasty et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Edward Paul Hasty (San Antonio, Texas); Dmitri Nickolaevich Ivanov (San Antonio, Texas) |
| ABSTRACT | Provided here are therapeutically effective pharmaceutical compositions containing one or more TREX2 inhibitors, and more specifically methods of administering TREX2 inhibitors to increase the effectiveness of a chemotherapeutic agent. Also provided here are methods of identifying agents that inhibit the exonuclease activity of TREX2. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/756705 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/24 (20130101) Original (OR) Class A61K 31/53 (20130101) A61K 31/136 (20130101) A61K 31/192 (20130101) A61K 31/352 (20130101) A61K 31/405 (20130101) A61K 31/655 (20130101) A61K 49/0043 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 2600/136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612583 | Dagda et al. |
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| FUNDED BY |
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| APPLICANT(S) | Nevada Research and Innovation Corporation (Reno, Nevada) |
| ASSIGNEE(S) | Nevada Research and Innovation Corporation (Reno, Nevada) |
| INVENTOR(S) | Raul Y. Dagda (Reno, Nevada); Ruben K. Dagda (Reno, Nevada) |
| ABSTRACT | The present invention relates to the discovery that Forskolin can be used to treat Parkinson's disease (PD) in subjects in need thereof. In certain embodiments, the invention provides a method of treating PD, wherein a therapeutically effective amount of Forskolin is administered to a subject via intranasal or intrapulmonary routes. In other embodiments, the subject is further administered a therapeutically effective amount of Noopept. In yet other embodiments, the method reverses damage to the subject's brain caused by PD and promotes growth of new neurons. |
| FILED | Thursday, June 20, 2019 |
| APPL NO | 17/055349 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/12 (20130101) A61K 9/0043 (20130101) A61K 31/352 (20130101) Original (OR) Class A61K 31/4015 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612586 | Alaniz et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Robert C. Alaniz (College Station, Texas); Arul Jayaraman (College Station, Texas); Kyongbum Lee (Winchester, Massachusetts) |
| ABSTRACT | The disclosure provides methods and compositions for affecting the development of antigen presenting cell (APC, e.g., a macrophage or dendritic cell). The methods include maturing an APC, promoting anti-inflammatory phenotype, promoting development of a T regulatory cell (Treg) from a naive T cell. The methods generally include exposing an APC to a tryptophan derived microbiota metabolite (TDMM), such as an anti-inflammatory or pro-mucosal TDMM, and permitting the APC to mature. In some embodiments, the conditioned APC is exposed to a naive T cell to further promote development of a T regulatory cell (Treg). In some embodiments, the TDMM is selected from the group consisting of indole, indole-3-acetate, 5-hydroxyindole, and indole-3-pyruvate. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 16/085912 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/405 (20130101) Original (OR) Class A61K 31/475 (20130101) A61K 31/7004 (20130101) A61K 35/17 (20130101) A61K 45/06 (20130101) A61K 2035/122 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 29/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/064 (20130101) C12N 5/0636 (20130101) C12N 5/0637 (20130101) C12N 2501/15 (20130101) C12N 2501/24 (20130101) C12N 2501/51 (20130101) C12N 2501/515 (20130101) C12N 2501/999 (20130101) C12N 2501/2301 (20130101) C12N 2501/2304 (20130101) C12N 2501/2306 (20130101) C12N 2501/2312 (20130101) C12N 2501/2321 (20130101) C12N 2501/2323 (20130101) C12N 2502/1121 (20130101) C12N 2502/1157 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612604 | Oegema et al. |
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| FUNDED BY |
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| APPLICANT(S) | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD (Zurich, Switzerland) |
| ASSIGNEE(S) | Ludwig Institute for Cancer Research Ltd (Zurich, Switzerland) |
| INVENTOR(S) | Karen Oegema (La Jolla, California); Andrew Shiau (La Jolla, California); Arshad Desai (La Jolla, California); Franz Meitinger (La Jolla, California); Robert Davis (La Jolla, California) |
| ABSTRACT | Provided herein, inter alia, are compounds and methods for inhibiting PLK4 and for treating cancer in a subject in need thereof. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/769458 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/506 (20130101) A61K 31/5377 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612618 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Henry Ford Health System (Detroit, Michigan) |
| ASSIGNEE(S) | Henry Ford Health System (Detroit, Michigan) |
| INVENTOR(S) | Jieli Chen (Troy, Michigan); Michael Chopp (Southfield, Michigan) |
| ABSTRACT | Provided herein are methods for the prevention and treatment of cardiovascular diseases and disorders in a subject diagnosed as having suffered a cerebrovascular injury by administering agents that contain or induce the expression of microRNA-126. |
| FILED | Wednesday, November 14, 2018 |
| APPL NO | 16/763290 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/127 (20130101) A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612619 | Honkanen et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Alabama Foundation for Research and Commercialization (Mobile, Alabama) |
| ASSIGNEE(S) | National Institute of Health (NIH), U.S. Dept. of Health and Human Services (DHHS), U.S. Government (Bethesda, Maryland) |
| INVENTOR(S) | Richard Eric Honkanen (Mobile, Alabama); Brandon Marshall D'Arcy (Mobile, Alabama); Mark Raymond Swingle (Mobile, Alabama) |
| ABSTRACT | Compositions, methods, and systems for modifying sterol metabolism in a subject is disclosed. In some embodiments, the subjects may be administered one or more mammalian cells modified to express at least one sterol degrading enzyme derived from a bacterium. In many embodiments, the cell is a macrophage or monocyte stably expressing three or more enzymes that aid in opening the β ring of cholesterol. The disclosed compositions and methods may be useful in lowering cholesterol levels in a subject in need thereof. In some embodiments, the subject may have a genetic predisposition to atherosclerosis. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 16/672185 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 2319/43 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/0077 (20130101) C12N 9/0095 (20130101) C12N 15/52 (20130101) C12N 15/62 (20130101) C12N 2710/16141 (20130101) C12N 2820/005 (20130101) C12N 2820/60 (20130101) Enzymes C12Y 101/01051 (20130101) C12Y 101/01145 (20130101) C12Y 103/01021 (20130101) C12Y 103/99004 (20130101) C12Y 106/02004 (20130101) C12Y 114/15 (20130101) C12Y 114/15006 (20130101) C12Y 118/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612636 | Kachlany et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); Actinobac Biomed, Inc. (Princeton, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey); ACTINOBAC BIOMED, INC. (Princeton, New Jersey) |
| INVENTOR(S) | Scott C. Kachlany (Bridgewater, New Jersey); Benjamin A. Belinka, Jr. (Newtown, Connecticut) |
| ABSTRACT | This invention concerns compositions and methods of treating or diagnosing inflammatory disorders and other disorders, as well as compositions and methods of treating HIV. |
| FILED | Thursday, April 01, 2021 |
| APPL NO | 17/220573 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) Original (OR) Class A61K 39/102 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 47/6849 (20170801) A61K 51/1093 (20130101) A61K 2039/505 (20130101) A61K 2039/55544 (20130101) Peptides C07K 16/2896 (20130101) C07K 2317/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5052 (20130101) G01N 33/56911 (20130101) G01N 33/56988 (20130101) G01N 2800/26 (20130101) G01N 2800/52 (20130101) G01N 2800/709 (20130101) G01N 2800/7095 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 530/825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612639 | Wagers et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Amy J. Wagers (Cambridge, Massachusetts); Richard T. Lee (Weston, Massachusetts) |
| ABSTRACT | Methods and compositions for rejuvenating skeletal muscle stem cells are disclosed. |
| FILED | Monday, October 08, 2018 |
| APPL NO | 16/154691 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1875 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612641 | Davidson et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Beverly L. Davidson (Iowa City, Iowa); John H. Lee (Iowa City, Iowa) |
| ABSTRACT | The present disclosure provides methods for treating or preventing Huntington's disease (HD) in a subject in need thereof, comprising administering a therapeutic agent that activates mTORC 1 function and/or increases Ras Homolog Enriched in Striatum (Rhes) level in the subject's brain as compared to the function or level in the subject prior to treatment, and methods for modulating mHTT-associated metabolic phenotypes and/or reversal of striatal atrophy by administering a therapeutic agent that activates mTORC1 function and/or increases Ras Homolog Enriched in Striatum (Rhes) level in the subject's brain as compared to the function or level in the subject prior to treatment. |
| FILED | Wednesday, December 30, 2015 |
| APPL NO | 15/540746 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0085 (20130101) A61K 38/46 (20130101) Original (OR) Class A61K 48/005 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 306/05002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612663 | Panitch et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Alyssa Panitch (Oakland, California); Emily Michelle Misnick (Oakland, California); Jenny B. Lin (Oakland, California); Kit S. Lam (Davis, California); Ruiwu Liu (Oakland, California); Dake Hao (Oakland, California); Aijun Wang (Sacramento, California) |
| ABSTRACT | The present disclosure provides pro-angiogenic proteoglycan mimetics that can provide a provisional, pro-angiogenic scaffold to support tissue regeneration while limiting systemic exposure to VEGF activity. These mimetics can protect a collagen matrix from rapid degradation, and in conjunction with EPCs promote angiogenesis in order to accelerate ischemic wound healing. For example, the provided compounds can be delivered from the end of a catheter following balloon angioplasty to coat the collagen exposed areas, prevent platelet binding and thrombosis, support capture of EPCs from blood to facilitate reendothelialization, and reduce late-lumen loss (neointimal hyperplasia). |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/062300 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/60 (20170801) A61K 47/61 (20170801) Original (OR) Class A61K 47/64 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612681 | Luo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Syracuse, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Syracuse, New York) |
| INVENTOR(S) | Juntao Luo (Jamesville, New York); Lili Wang (Syracuse, New York); Changying Shi (Jamesville, New York) |
| ABSTRACT | Provided are sorption materials and devices using the sorption materials, and methods of using the sorption materials and devices containing the sorption materials. In various examples, the sorption materials bind to various inflammation stimulating and/or mediating molecules, which are often associated with systemic infections and systemic inflammation associated with conditions such as, for example, sepsis. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/644782 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3679 (20130101) A61M 1/3687 (20130101) Original (OR) Class Separation B01D 15/20 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/262 (20130101) B01J 20/3214 (20130101) B01J 20/3219 (20130101) B01J 20/3272 (20130101) B01J 20/28047 (20130101) B01J 20/28054 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/68 (20130101) C02F 1/285 (20130101) C02F 1/685 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613514 | Thomas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Craig Thomas (Gaithersburg, Maryland); Carlos Zarate (Germantown, Maryland); Ruin Moaddel (Bel Air, Maryland); Todd Gould (Elkridge, Maryland); Panos Zanos (Baltimore, Maryland); Patrick Morris (Columbia, Maryland) |
| ABSTRACT | The disclosure provides a method for synthesizing free base forms of (2R,6R)-hydroxynorketamine (HNK) and (2S,6S)-hydroxynorketamine. In an embodiment synthesis of (2R,6R)-hydroxynorketamine (HNK) includes preparation of (R)-norketamine via chiral resolution from racemic norketamine via a chiral resolution with L-pyroglutamic acid. The disclosure also provided crystal forms of the corresponding (2R,6R)-hydroxynorketamine (HNK) and (2S,6S)-hydroxynorketamine hydrochloride salts. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/155162 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Acyclic or Carbocyclic Compounds C07C 221/00 (20130101) C07C 221/00 (20130101) C07C 225/20 (20130101) Original (OR) Class C07C 225/20 (20130101) C07C 269/06 (20130101) C07C 269/06 (20130101) C07C 271/24 (20130101) C07C 2601/14 (20170501) C07C 2601/16 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613517 | Scanlan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Thomas S. Scanlan (Portland, Oregon); Skylar J. Ferrara (Portland, Oregon) |
| ABSTRACT | Provided herein are novel amide prodrug forms of pharmaceutically active agents useful for central nervous system disorders. |
| FILED | Tuesday, February 26, 2019 |
| APPL NO | 16/971171 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/65 (20130101) C07C 235/34 (20130101) Original (OR) Class C07C 309/66 (20130101) C07C 2602/10 (20170501) Heterocyclic Compounds C07D 261/20 (20130101) C07D 277/26 (20130101) C07D 409/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613538 | Graci et al. |
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| FUNDED BY |
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| APPLICANT(S) | PTC Therapeutics, Inc. (South Plainfield, New Jersey) |
| ASSIGNEE(S) | PTC Therapeutics, Inc. (South Plainfield, New Jersey) |
| INVENTOR(S) | Jason Graci (West Orange, New Jersey); Zhengxian Gu (Shanghai, China PRC) |
| ABSTRACT | Compounds that inhibit viral replication or the production of viral RNA or DNA or viral protein and compositions comprising such Compounds are described. Also described are methods of inhibiting or reducing viral replication or the production of viral RNA or DNA or viral protein using such Compounds, and methods for treating viral infections, such as an RNA virus belonging to the family Coronaviridae, involving the administration of such Compounds. The Compounds may be administered as a single agent therapy or in combination with one or more additional therapies to a human in need of such treatments. |
| FILED | Tuesday, June 23, 2020 |
| APPL NO | 16/909394 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/437 (20130101) A61K 31/4745 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613544 | Backes et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); University of Washington Through Its Center For Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Washington Through Its Center For Commercialization (Seattle, Washington) |
| INVENTOR(S) | Bradley J. Backes (San Francisco, California); Dustin J. Maly (Seattle, Washington); Scott A. Oakes (San Francisco, California); Feroz R. Papa (San Francisco, California); Gayani Perera (Nugegoda, Sri Lanka); Likun Wang (San Francisco, California) |
| ABSTRACT | Described herein, inter alia, are certain substituted imidazo[1,5-a]pyrazines of formula (I) and methods of using the same for modulating the activity of Ire1. |
| FILED | Thursday, September 24, 2020 |
| APPL NO | 17/031132 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613547 | Majumdar et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Health Sciences and Pharmacy in St. Louis (St. Louis, Missouri); University of Southern California (Los Angeles, California); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Memorial Sloan Kettering Cancer Center (New York, New York); University of Florida Research Foundation, Incorporated (Gainesville, Florida); Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | University of Health Sciences and Pharmacy in St. Louis (St. Louis, Missouri); University of Southern California (Los Angeles, California); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Memorial Sloan Kettering Cancer Center (New York, New York); University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Susruta Majumdar (St. Louis, Missouri); Vsevolod Katritch (Los Angeles, California); Bryan Roth (Chapel Hill, North Carolina); Jay McLaughlin (Gainesville, Florida); Saheem Zaidi (Los Angeles, California); Gavril W. Pasternak (, None); Rajendra Uprety (Cary, North Carolina) |
| ABSTRACT | In some aspects, the present disclosure provides compounds of the formula: wherein the variables are as defined herein. In some embodiments, these compounds may be used to reduce the pain of a patient. These compounds may be used in pain relief and show an improved pharmaceutical profile relative to other commonly used opiates and opioid derivatives. |
| FILED | Wednesday, July 08, 2020 |
| APPL NO | 16/924037 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 221/28 (20130101) C07D 489/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613603 | Hearon et al. |
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| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Keith Hearon (College Station, Texas); Landon D. Nash (College Station, Texas); Thomas Wilson (Livermore, California); Duncan J. Maitland (College Station, Texas); Mark A. Wierzbicki (College Station, Texas) |
| ABSTRACT | An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein. |
| FILED | Thursday, July 09, 2020 |
| APPL NO | 16/924819 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/675 (20130101) C08G 18/758 (20130101) C08G 18/3206 (20130101) Original (OR) Class C08G 18/3212 (20130101) C08G 18/6715 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/16 (20130101) C08L 81/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613729 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Yan Li (Tallahassee, Florida); Teng Ma (Tallahassee, Florida) |
| ABSTRACT | Improved hybrid neurovascular spheroids and methods for making the same are provided. In some embodiments of a method for making a hybrid neurovascular spheroid, the method includes i) propagating cortical cells to form a cortical spheroid; ii) propagating endothelial cells to form an endothelial spheroid; iii) propagating mesenchymal stem cells to form a mesenchymal cell culture; and iv) combining the cortical spheroid, endothelial spheroid, and mesenchymal spheroid under conditions to form the hybrid neurovascular spheroid. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821395 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0618 (20130101) Original (OR) Class C12N 2501/20 (20130101) C12N 2501/165 (20130101) C12N 2501/999 (20130101) C12N 2502/08 (20130101) C12N 2502/28 (20130101) C12N 2502/088 (20130101) C12N 2502/1352 (20130101) C12N 2513/00 (20130101) C12N 2533/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613754 | Peter et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Marcus E. Peter (Chicago, Illinois); William E. Putzbach (Lombard, Illinois); Andrea E. Murmann (Chicago, Illinois); Monal Patel (Des Plaines, Illinois); Quan Gao (Chicago, Illinois) |
| ABSTRACT | Disclosed are polynucleotides, compositions, and methods related to RNA interference (RNAi). The disclosed polynucleotides, compositions, and methods may be utilized for treating diseases and disorders through RNAi. Particular disclosed are toxic RNAi active seed sequences and methods of using toxic RNAi active sequences for killing cancer cells. The disclosed toxic RNAi active seed sequences preferentially target and inhibit the expression of multiple essential genes for cell survival and/or growth through a process called “death-induced by survival gene elimination” or “DISE.” |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/900392 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 47/64 (20170801) A61K 47/6931 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/122 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) C12N 2320/10 (20130101) C12N 2320/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613758 | Hasty et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeff Hasty (Encinitas, California); Lev Tsimring (San Diego, California); Muhammad Omar Din (San Diego, California); Arthur Prindle (San Diego, California); Sangeeta Bhatia (Lexington, Massachusetts); Tal Danino (Cambridge, Massachusetts) |
| ABSTRACT | Some embodiments described herein relate to cells which have been genetically engineered to release a polypeptide when a population of the cells reaches a desired density. In some embodiments, the released polypeptide may be a therapeutic polypeptide. In some embodiments, the therapeutic polypeptide kills tumor cells or which inhibits the growth of tumor cells. |
| FILED | Thursday, November 11, 2021 |
| APPL NO | 17/524332 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 38/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/06 (20130101) C12N 1/20 (20130101) C12N 15/63 (20130101) C12N 15/74 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613775 | de Paz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Alexandra M. de Paz (Evanston, Illinois); Keith E.J. Tyo (Evanston, Illinois) |
| ABSTRACT | Provided herein are systems and methods for high-resolution mapping of DNA polymerase fidelity using nucleotide imbalances and next-generation sequencing. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/231013 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6848 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613780 | Leng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fenfei Leng (Palmetto Bay, Florida); Xiaoduo Zhi (Volo, Illinois); Samantha Dages (Miami, Florida); Kelley Dages (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Fenfei Leng (Palmetto Bay, Florida); Xiaoduo Zhi (Volo, Illinois); Samantha Dages (Miami, Florida); Kelley Dages (Miami, Florida) |
| ABSTRACT | The disclosure describes the effects of transcription mediated from a promoter on the transcription mediated by divergently coupled supercoiling-sensitive promoter. Transcription initiated from a promoter inhibits transcription mediated by a specific supercoiling-sensitive promoter that is divergently coupled to the promoter. A gyrase inhibitor relieves this inhibition and substantially increases the transcription mediated by the specific supercoiling-sensitive promoter that is divergently coupled to another promoter. Accordingly, the invention pertains to a method for identifying a compound as a gyrase inhibitor or not a gyrase inhibitor based on differential expression of genes under the control of divergently coupled promoters in the presence of the compound. Another embodiment of the invention provides an assay for identifying one or more compounds from a library of compounds as a gyrase inhibitor. Polynucleotides and cells containing such polynucleotides that are suitable for carrying out the methods described herein are also provided. |
| FILED | Friday, June 15, 2018 |
| APPL NO | 16/009735 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/90 (20130101) C12N 15/63 (20130101) C12N 15/70 (20130101) C12N 15/1086 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) C12Q 1/66 (20130101) C12Q 1/533 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Enzymes C12Y 599/01003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613781 | Salk et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/392193 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613782 | Suliman et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CAPE TOWN (Cape Town, South Africa); STELLENBOSCH UNIVERSITY (Cape Town, South Africa); SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington); MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V (Munich, Germany); UNITED KINGDOM RESEARCH AND INNOVATION (Swindon, United Kingdom) |
| ASSIGNEE(S) | UNIVERSITY OF CAPE TOWN (Cape Town, South Africa); STELLENBOSCH UNIVERSITY (Cape Town, South Africa); SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington); MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V (Munich, Germany); UNITED KINGDOM RESEARCH AND INNOVATION (Swindon, United Kingdom) |
| INVENTOR(S) | Sara Suliman (Brookline, Massachusetts); Ethan Greene Thompson (Seattle, Washington); Jayne Suzanne Sutherland (Banjul, Gambia); Stefan H. E. Kaufmann (Berlin, Germany); Thomas Jens Scriba (Cape Town, South Africa); Daniel Edward Zak (Seattle, Washington); Gerhard Walzl (Cape Town, South Africa) |
| ABSTRACT | The invention provides a gene signature for use in determining a likelihood of a latent tuberculosis (TB) infection in a subject transitioning to active TB disease. The gene signature comprises at least SEPT4 and BLK, and optionally also GAS6 and/or CD1C. Expression levels of these genes are detected in a sample from the subject, and the ratios of expression of at least two of the above genes are calculated (e.g. SEPT4:BLK, SEPT4:CD1C, GAS6:BLK and/or GAS6:CD1C). A score is assigned to each ratio, the score being indicative of the likelihood of the latent TB infection transitioning into active TB disease, based on the ratio for the respective gene pair. The subject can be identified as having a latent TB infection that is likely to transition into active TB disease or that is not likely to transition into active TB disease based on the score or on the average of the scores. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/980121 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613784 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Liang Liu (Flushing, New York); Yao Shen (New York, New York) |
| ABSTRACT | The present invention provides methods of detecting ultraviolet radiation (UVR)-induced skin damage in a subject. The method includes the steps of: a) obtaining a skin sample from the subject; b) analyzing expression levels in the skin sample of UVR-induced differentially expressed genes (DEGs) listed in Table 8 or a subset thereof; and c) comparing the expression levels of the UVR-induced DEGs to a control skin sample; wherein, when the expression levels of the UVR-induced DEGs in the skin sample is above or below the level of each of the UVR-induced DEGs in the control sample, the subject is identified as likely being afflicted with UVR-induced skin damage. Also provided are methods for measuring the effectiveness of a test agent in reducing ultraviolet radiation (UVR)-induced damage. |
| FILED | Thursday, March 16, 2017 |
| APPL NO | 16/072825 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613786 | McCarroll et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Steven A. McCarroll (Cambridge, Massachusetts); Giulio Genovese (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to clonal expansion of somatic cells in subjects, and acquired selective advantage of cell clones during the lifetime of a subject. In particular, the invention relates to methods for predicting the development of cancer based on the observation of specific genetic mutations in somatic cell clones, as well as to methods for treating or preventing cancer in a subject, in which clonal expansion of cells comprising specific modifications is observed. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/858085 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/91017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613787 | Kurtz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | David M. Kurtz (San Carlos, California); Maximilian Diehn (San Carlos, California); Arash Ash Alizadeh (San Mateo, California) |
| ABSTRACT | Processes and materials to detect cancer from a biopsy are described. In some cases, cell-free nucleic acids can be sequenced, and the sequencing result can be utilized to detect sequences derived from a neoplasm. Detection of somatic variants occurring in phase can indicate the presence of cancer in a diagnostic scan and a clinical intervention can be performed. |
| FILED | Wednesday, December 29, 2021 |
| APPL NO | 17/646473 |
| ART UNIT | 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1089 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/10 (20190201) G16B 20/20 (20190201) G16B 30/00 (20190201) G16B 30/10 (20190201) G16B 35/20 (20190201) G16B 40/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 10/60 (20180101) G16H 20/10 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 50/70 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614437 | Hickman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | James Hickman (Orlando, Florida); Maria Stancescu (Orlando, Florida); Peter Molnar (Orlando, Florida); Christopher Long (Orlando, Florida); Christopher McAleer (Orlando, Florida) |
| ABSTRACT | In an aspect, disclosed herein are physiological devices and systems, and components thereof, used to evaluate cardiac parameters and arrhythmogenic mechanisms. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 16/913528 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 41/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614548 | Adler |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Stephen S. Adler (Chevy Chase, Maryland) |
| ABSTRACT | Methods and apparatus for calibrating radioactive sources are described. An array of scintillation detectors form a receptacle within which a sample or sample container can be retained by a holder. The scintillation detectors are coupled via light transducers such as photomultiplier tubes (PMTs) to independent electronic counters. Coincidence processing of time-tagged events yields a correlated event rate. One or more corrections can be applied as needed, for background counts, deadtime, or random coincidences. Voltage tuning of PMTs yields improved reproducibility. Variations are disclosed. 1% accuracy has been demonstrated over a range of 10 kBq-3 MBq, covering a gap in the capabilities of conventional technology. |
| FILED | Friday, May 07, 2021 |
| APPL NO | 17/314355 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/167 (20130101) Original (OR) Class G01T 1/2006 (20130101) G01T 1/2023 (20130101) G01T 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614610 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ALLEN INSTITUTE (Seattle, Washington) |
| ASSIGNEE(S) | ALLEN INSTITUTE (Seattle, Washington) |
| INVENTOR(S) | Gregory Johnson (Seattle, Washington); Chawin Ounkomol (Seattle, Washington); Forrest Collman (Seattle, Washington); Sharmishtaa Seshamani (Shoreline, Washington) |
| ABSTRACT | A computing device, method, system, and instructions in a non-transitory computer-readable medium for performing image analysis on 3D microscopy images to predict localization and/or labeling of various structures or objects of interest, by predicting the location in such images at which a dye or other marker associated with such structures would appear. The computing device, method, and system receives sets of 3D images that include unlabeled images, such as transmitted light images or electron microscope images, and labeled images, such as images captured with fluorescence tagging. The computing device trains a statistical model to associate structures in the labeled images with the same structures in the unlabeled light images. The processor further applies the statistical model to a new unlabeled image to generate a predictive labeled image that predicts the location of a structure of interest in the new image. |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/148192 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0454 (20130101) G06N 20/20 (20190101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/174 (20170101) G06T 7/187 (20170101) G06T 2207/10061 (20130101) G06T 2207/10064 (20130101) G06T 2207/30024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11615687 | DeMazumder |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University Of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University Of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Deeptankar DeMazumder (Baltimore, Maryland) |
| ABSTRACT | A system and a method for predicting kinesthetic outcomes from observed position, posture, behavior or activity of an individual 1602, 1702. The system uses kinesthetic activity sensors 102, 104 each collecting one or more of audio, video, or physiological signals and capturing the activity of the individual or an ambient environment of the individual. These signals are delivered into a computer system 106 implementing a learning routine 108 which constructs one or more personalized kinetic state models 1510 of positional states for the individual and transitions between the positional states, and further develops one or more customized multi-dimensional prediction models 1500 for the individual and uses the multidimensional prediction models to predict behaviors, activities and/or positional changes likely to occur in the future, and provides notice of predicted unsafe or undesired outcomes. |
| FILED | Monday, January 28, 2019 |
| APPL NO | 16/960264 |
| ART UNIT | 2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/08 (20130101) A61B 5/021 (20130101) A61B 5/0077 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/1113 (20130101) A61B 5/02405 (20130101) A61B 5/4806 (20130101) A61B 5/4866 (20130101) A61B 5/14551 (20130101) A61B 2560/0242 (20130101) A61B 2560/0431 (20130101) A61B 2560/0475 (20130101) A61B 2562/0204 (20130101) A61B 2562/0219 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/043 (20130101) Original (OR) Class G08B 21/0453 (20130101) G08B 21/0476 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) G16H 50/20 (20180101) G16H 50/50 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11615864 | Salzman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Julia Salzman (Palo Alto, California) |
| ABSTRACT | Unveiling of chimeric biomolecule sequences and applications thereof are described. Generally, systems comprising statistical analysis are performed to unveil chimeric biomolecule sequences from sequencing data sets. Bloom filters and hierarchical bloom filter tree data structures can be constructed such that chimeric sequence unveiling systems are more efficient. Finally, chimeric sequences are used to develop research tools, diagnostics, and medicaments. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 16/487033 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9027 (20190101) G06F 30/20 (20200101) G06F 2111/10 (20200101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/20 (20190201) G16B 30/10 (20190201) Original (OR) Class G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE49474 | Golkowski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STERIFRE MEDICAL, INC. (Kirkland, Washington) |
| ASSIGNEE(S) | Sterifre Medical, Inc. (Kirkland, Washington) |
| INVENTOR(S) | Czeslaw Golkowski (Ithaca, New York) |
| ABSTRACT | A free radical sterilization system having a chamber defining a region, and a generator for generating free radical reach effluent from a free radical electric generator and/or a vaporizer. A closed loop circulating system without a free-radical destroyer is provided for supplying the mixture of free radicals from the electric generator mixed with the hydrogen peroxide solution in the form of the effluent to the chamber. The free-radical sterilization system is used in sterilizing items in the chamber and, with an open-bottomed wound chamber, in treating wounds on a body. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 16/542205 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0294 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/00 (20130101) Original (OR) Class A61L 2/22 (20130101) A61L 2/186 (20130101) A61L 2/208 (20130101) A61L 9/00 (20130101) A61L 9/03 (20130101) A61L 9/015 (20130101) A61L 11/00 (20130101) A61L 2202/11 (20130101) A61L 2202/14 (20130101) A61L 2202/15 (20130101) A61L 2202/26 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/69 (20210501) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 12/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE49477 | Fertala et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THOMAS JEFFERSON UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Andrzej Fertala (Voorhees, New Jersey); Andrzej Steplewski (Phoenixville, Pennsylvania) |
| ABSTRACT | A chimeric, humanized or single-chain antibody contains a light chain variable region containing the complementarity determining regions of SEQ ID NO: 1, SEQ ID NO:2 and SEQ ID NO:3, and a heavy chain variable region containing the complementarity determining regions SEQ ID NO:4, SEQ ID NO:5 and SEQ ID NO:6. The antibody or antibody fragment thereof is capable of binding the C-terminal telopeptide of the α2(I) chain of human collagen I, and is useful in the treatment of diseases or disorders associated with excessive collagen fibril. |
| FILED | Wednesday, October 02, 2019 |
| APPL NO | 16/590929 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11612399 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the Stevens Institute of Technology (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Xiaojun Yu (Fishers, Indiana); Munish B. Shah (Galloway, New Jersey); Wei Chang (New York, New York) |
| ABSTRACT | A nerve guidance conduit includes one or more guidance channels formed as porous polymeric structures. The guidance channels are within an outer tubular structure that includes randomly-oriented nanofibers. The guidance channels may have electrospun nanofibers on their inner and outer surfaces in a parallel alignment with the guidance channels. Such aligned nanofibers may also be present on the inner surface of the outer tubular structure. The outer surfaces of the guidance channels and the inner surface of the tubular structure define additional guidance channels. Such a nerve guidance conduit provides augmented surface areas for providing directional guidance and enhancing peripheral nerve regeneration. The structure also has the mechanical and nutrient transport requirements required over long regeneration periods. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/448550 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1128 (20130101) Original (OR) Class A61B 2017/00526 (20130101) A61B 2017/1132 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/50 (20130101) A61L 27/56 (20130101) A61L 2400/12 (20130101) A61L 2430/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612748 | Provenza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Nicole Provenza (Providence, Rhode Island); David Borton (Pawtucket, Rhode Island); Alik Widge (Somerville, Massachusetts); Darin Dougherty (Charlestown, Massachusetts); Emad Eskandar (Boston, Massachusetts) |
| ABSTRACT | In accordance with some embodiments of the disclosed subject matter, mechanisms (which can, for example, include systems, methods, and media) for detecting an effortful mental state providing real-time deep brain stimulation to enhance performance of effortful mental tasks are provided. In some embodiments, system for detecting and facilitating effortful mental states is provided, the system comprising: monitoring sensors to capture neural activity from a subject's brain; an implanted stimulator to provide electrical stimulation to the subject's brain; a hardware processor programmed to: correlate activity in a first and second region of the subject brain during task performance; correlate activity in the first and second regions during task non performance; train a support vector machine (SVM) using the correlations as first and second class examples; and provide stimulation to augment brain function when the SVM indicates, based on activity in the first and second regions, the subject is in the mental state. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 16/607989 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/37 (20210101) A61B 5/291 (20210101) A61B 5/6847 (20130101) A61B 5/7267 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 1/36092 (20130101) Original (OR) Class A61N 1/36139 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612893 | Selden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ANDE Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | ANDE CORPORATION (Waltham, Massachusetts) |
| INVENTOR(S) | Richard F. Selden (Lincoln, Massachusetts); Eugene Tan (Lexington, Massachusetts) |
| ABSTRACT | A biochip for the integration of all steps in a complex process from the insertion of a sample to the generation of a result, performed without operator intervention includes microfluidic and macrofluidic features that are acted on by instrument subsystems in a series of scripted processing steps. Methods for fabricating these complex biochips of high feature density by injection molding are also provided. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/368180 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Separation B01D 69/02 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502723 (20130101) B01L 3/502738 (20130101) B01L 3/502753 (20130101) B01L 7/52 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2200/12 (20130101) B01L 2200/16 (20130101) B01L 2200/027 (20130101) B01L 2200/142 (20130101) B01L 2300/18 (20130101) B01L 2300/087 (20130101) B01L 2300/123 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0819 (20130101) B01L 2300/0861 (20130101) B01L 2300/0864 (20130101) B01L 2300/0874 (20130101) B01L 2300/1822 (20130101) B01L 2400/0421 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) B01L 2400/0655 (20130101) B01L 2400/0677 (20130101) B01L 2400/0688 (20130101) Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 11/08 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0025 (20130101) B29C 2045/0027 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) B29K 2105/251 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/26 (20130101) G01N 27/44704 (20130101) G01N 27/44721 (20130101) G01N 27/44743 (20130101) G01N 27/44791 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4998 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11612894 | Selden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ANDE Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | ANDE CORPORATION (Waltham, Massachusetts) |
| INVENTOR(S) | Richard F. Selden (Lincoln, Massachusetts); Eugene Tan (Lexington, Massachusetts) |
| ABSTRACT | A biochip for the integration of all steps in a complex process from the insertion of a sample to the generation of a result, performed without operator intervention includes microfluidic and macrofluidic features that are acted on by instrument subsystems in a series of scripted processing steps. Methods for fabricating these complex biochips of high feature density by injection molding are also provided. |
| FILED | Thursday, January 26, 2017 |
| APPL NO | 15/416603 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Separation B01D 69/02 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502723 (20130101) B01L 3/502738 (20130101) B01L 3/502753 (20130101) B01L 7/52 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2200/12 (20130101) B01L 2200/16 (20130101) B01L 2200/027 (20130101) B01L 2200/142 (20130101) B01L 2300/18 (20130101) B01L 2300/087 (20130101) B01L 2300/123 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0819 (20130101) B01L 2300/0861 (20130101) B01L 2300/0864 (20130101) B01L 2300/0874 (20130101) B01L 2300/1822 (20130101) B01L 2400/0421 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) B01L 2400/0655 (20130101) B01L 2400/0677 (20130101) B01L 2400/0688 (20130101) Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 11/08 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0025 (20130101) B29C 2045/0027 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) B29K 2105/251 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/26 (20130101) G01N 27/44704 (20130101) G01N 27/44721 (20130101) G01N 27/44743 (20130101) G01N 27/44791 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4998 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613051 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); David H. Wang (Beavercreek, Ohio) |
| ABSTRACT | The invention generally relates to polymer nanocomposite films that possess shape memory properties at elevated temperatures. Such films can absorb microwaves, are thermally conductive, are electrically conductive and have increased mechanical strength. In addition, the present invention relates to methods of fabricating such films into 3D objects. Due to the improved properties of such films more advanced sensors and microwave shields can be constructed. |
| FILED | Monday, January 27, 2020 |
| APPL NO | 16/752787 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/003 (20130101) Original (OR) Class B29C 41/46 (20130101) B29C 2791/001 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2079/085 (20130101) B29K 2105/246 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/14 (20130101) C08G 73/1007 (20130101) C08G 73/1067 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/041 (20170501) C08K 3/042 (20170501) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 79/08 (20130101) C08L 2201/12 (20130101) C08L 2312/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613077 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Hsiang H. Liu (Lakewood, Colorado); James O. Hardin, IV (Enon, Ohio); John D. Berrigan (Beavercreek, Ohio) |
| ABSTRACT | The present invention relates to 3-D structures having high temperature stability and improved micro-porosity as well as processes of making and using same. The disclosed 3-D are advantageous because they have low densities and low permittivities. When compared to previous 3-D structures, the present structures maintain their low permittivities over a broader range of electromagnetic frequencies. Thus, when used in communication devices such as array antennas, can provided higher communication performance in high temperature environments. |
| FILED | Tuesday, July 28, 2020 |
| APPL NO | 16/940421 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) Original (OR) Class B29C 64/209 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) B29K 2079/08 (20130101) B29K 2081/06 (20130101) B29K 2083/00 (20130101) B29K 2995/0017 (20130101) B29K 2995/0077 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 70/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613219 | Bernhardt |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Arlington, Virginia) |
| INVENTOR(S) | Roger D. Bernhardt (St. Louis, Missouri) |
| ABSTRACT | The present disclosure provides a structural member for a vehicle. The structural member comprises a plurality of finned spar members interlocked with one another, wherein each finned spar member of the plurality of finned spar members includes a main body, a plurality of web members extending from a flange of the main body, a circuit board formed on the main body, and a bus bar comprising a tube positioned in an opening formed in the main body, the bus bar being in electrical communication with the circuit board, wherein a compartment is formed between adjacent web members, the compartment being sized to receive a battery. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/437800 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 16/04 (20130101) Original (OR) Class Aeroplanes; Helicopters B64C 3/32 (20130101) B64C 3/185 (20130101) B64C 2201/042 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/26 (20130101) B64D 2221/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/20 (20210101) Boards, Substations, or Switching Arrangements for the Supply or Distribution of Electric Power H02B 1/20 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 5/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613344 | Ol et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Michael V Ol (Xenia, Ohio); Alberto Medina (Fairborn, Ohio) |
| ABSTRACT | A wing, a method of controlling lift on a wing, and a system to produce lift on a wing are provided. The wing may include a fore-element, an aft-element, a pivotable linkage that operatively connects the aft-element leading edge to the fore-element trailing edge in a span-wise direction, and an actuator. The actuator may deflect the aft-element through a predetermined deflection angle about the pivotable linkage relative to the fore-element within less than or equal to two convective periods. The method may include deflecting a span-wise flap through the deflection angle in less than or equal to two convective periods to produce high lift. The system may include a sensor to detect an input and a controller to deflect the span-wise flap of the wing by the deflection angle in not more than two convective periods based on the received input signal. |
| FILED | Tuesday, March 02, 2021 |
| APPL NO | 17/189363 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 1/28 (20130101) B63B 1/248 (20130101) Aeroplanes; Helicopters B64C 3/48 (20130101) B64C 9/28 (20130101) Original (OR) Class B64C 13/16 (20130101) B64C 13/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613365 | Al-Husseini |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mahdi Al-Husseini (Douglasville, Georgia) |
| ASSIGNEE(S) | United States Army Airborne School (Fort Benning, Georgia) |
| INVENTOR(S) | Mahdi Al-Husseini (Douglasville, Georgia) |
| ABSTRACT | Disclosed are various embodiments for an electromagnetic automatic deactivation device (ADD). An ADD may be used with an ejector-spring static line reserve parachute, common in low-altitude military jumps. Activating a reserve parachute from within an aircraft, while being towed by an aircraft, or when trapped inside another parachute, can result in significant injury, and may be fatal. An ADD may be added to the internal packaging of a reserve parachute to prevent its accidental activation. An ADD may be configured to sense ambient pressure, linear and rotational motion, and other data, to identify hazardous environmental conditions. An ADD may be further configured to support a towed jumper whose static line is cut, by strategically deactivating the electromagnetic assembly, and therefore activating the reserve parachute. The ADD may be modified to include the ability to override the ADD with a secondary pull on the ripcord handle. |
| FILED | Thursday, December 23, 2021 |
| APPL NO | 17/561200 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 17/60 (20130101) B64D 17/70 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613746 | Coppock |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Matthew B. Coppock (Arlington, Virginia) |
| ABSTRACT | A method for developing capture agents for target proteins employs a compound library to find cyclic peptide sequences that bind the target protein. The target protein is also reacted with a clickable group-provider reagent to provide the protein with clickable groups. The compounds in the library are provided with complementary clickable groups that bind the clickable group on the target protein when the peptide sequences bind the target protein. In some embodiments, the cyclic peptide sequences that bind the target protein are incorporated into constructs having one or more arms that can serve as capture agents or potential treatments against the pathogens from which the target protein is derived. Some embodiments provide pharmaceutical compositions for immunoassays, diagnostics, therapeutics or the like, that employ the constructs. |
| FILED | Thursday, May 09, 2019 |
| APPL NO | 16/407780 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class C12N 15/1072 (20130101) C12N 15/1086 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/02 (20130101) C40B 40/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/543 (20130101) G01N 33/5008 (20130101) G01N 33/6845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614301 | Seghi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven Seghi (Bloomington, Indiana); Kevin Kellar (Crane, Indiana) |
| ABSTRACT | The invention relates to quick acting interfaces that allow for easier transportation and maintenance of precision rifles. Embodiments include an interface with an engaging segment and a receiving segment that engage one another and lock together. The engaging segment may have a series of connective bearings that fit into indentations inside the receiving segment. Embodiments allow a firearm to be modulated such that a barrel of the firearm may be disassembled without the need of any specialized equipment and reassembled without impacting the firearm's accuracy or reliability. Embodiments are scalable such that multiple interfaces can be used to adjust the total length of the firearm barrel. |
| FILED | Tuesday, March 16, 2021 |
| APPL NO | 17/202819 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/482 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614313 | Shaw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Anthony Shaw (Madison, New Jersey); Jay Poret (Sparta, New Jersey); Lori Groven (Rapid City, South Dakota); Joshua Koenig (Rapid City, South Dakota); Jason Brusnahan (Semaphore Park, Australia) |
| ABSTRACT | The present invention is a pyrotechnic time delay system that is improved over prior-art designs. Specifically, the system described herein comprises at least one delay element. The delay element or delay elements each have an input charge, a delay composition, and an output charge. Both the input charge and the output charge are igniter compositions and are comprised of the same components despite having different functional goals. The input charge and output charge compositions preferably contain titanium, manganese dioxide, and polytetrafluoroethylene. The delay composition may be modified from current formulations to include manganese and manganese dioxide, or tungsten and manganese dioxide. The system disclosed herein may be comprised of one delay element, or it may be modular wherein multiple delay elements are connected in series. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/389598 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/00 (20130101) C06B 33/00 (20130101) Detonating or Priming Devices; Fuses; Chemical Lighters; Pyrophoric Compositions C06C 5/00 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 9/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
11614365 — Luminescent cold shield paneling for infrared camera continuous non-uniformity correction
| US 11614365 | Reeves et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration, Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Jeremy B. Reeves (Chelmsford, Massachusetts); Steven R. Jost (Amherst, New Hampshire); Paul R. Moffitt (Hollis, New Hampshire); Ian B. Murray (Amherst, New Hampshire); David J. Shelton (Ocoee, Florida); Raymond D. Tower, Jr. (Nashua, New Hampshire) |
| ABSTRACT | A luminescent diode surface within the cold shield of an infrared camera to allow for continuous non-uniformity correction with uniform irradiance across an infrared IR detector array. Further provided by the inclusion of a luminescent diode surface within the cold shield paneling is the ability to change the diode bias providing a negative luminescent effect while utilizing reverse bias and an electro-luminescent effect while utilizing a forward bias. This may then further allow for multiple set points to provide continuous offset and gain correction and to correct non-linear response effects. |
| FILED | Tuesday, April 13, 2021 |
| APPL NO | 17/229310 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/06 (20130101) G01J 5/53 (20220101) G01J 5/061 (20130101) Original (OR) Class G01J 5/80 (20220101) G01J 2005/065 (20130101) G01J 2005/0077 (20130101) G01J 2005/528 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) H04N 25/671 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614552 | Penny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Decision Sciences International Corporation (Poway, California) |
| ASSIGNEE(S) | Decision Sciences International Corporation (Poway, California) |
| INVENTOR(S) | Robert D. Penny (San Diego, California); Michael James Sossong (Ramona, California); Matthew Steiger (El Cajon, California); Young K. Lee (San Diego, California) |
| ABSTRACT | A volume interrogation system can use an accelerated beam of charged particles to interrogate objects using charged-particle attenuation and scattering tomography to screen items such as portable electronic devices, packages, baggage, industrial products, or food products for the presence of materials of interest inside. The exemplary systems and methods in this patent document can be employed in checkpoint applications to scan items. Such checkpoint applications can include border crossings, mass transit terminals (subways, buses, railways, ferries, etc.), and government and private-sector facilities. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/853520 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 5/08 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/32 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/001 (20130101) H05H 7/04 (20130101) H05H 13/00 (20130101) H05H 2007/002 (20130101) H05H 2007/045 (20130101) H05H 2277/1405 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614583 | Shepherd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Robert Shepherd (Ithaca, New York); Hedan Bai (Ithaca, New York); Shuo Li (Ithaca, New York); Yaqi Tu (Ithaca, New York) |
| ABSTRACT | A waveguide is provided. The waveguide having a first core, a second core spaced apart from and parallel with the first core, and a cladding surrounding the first core and the second core. An interstitial portion of the cladding is located between the first core and the second core. A first region of the first core adjacent to the cladding or of the cladding adjacent to the first core is color dyed. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/767918 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) G02B 6/1221 (20130101) Original (OR) Class G02B 2006/12069 (20130101) G02B 2006/12097 (20130101) G02B 2006/12138 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614643 | Peng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Cheng Peng (Beijing, China PRC); Christopher Louis Panuski (Somerville, Massachusetts); Ryan Hamerly (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | A reflective spatial light modulator (SLM) made of an electro-optic material in a one-sided Fabry-Perot resonator can provide phase and/or amplitude modulation with fine spatial resolution at speeds over a Gigahertz. The light is confined laterally within the electro-optic material/resonator layer stack with microlenses, index perturbations, or by patterning the layer stack into a two-dimensional (2D) array of vertically oriented micropillars. Alternatively, a photonic crystal guided mode resonator can vertically and laterally confine the resonant mode. In phase-only modulation mode, each SLM pixel can produce a π phase shift under a bias voltage below 10 V, while maintaining nearly constant reflection amplitude. This high-speed SLM can be used in a wide range of new applications, from fully tunable metasurfaces to optical computing accelerators, high-speed interconnects, true 2D phased array beam steering, beam forming, or quantum computing with cold atom arrays. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/876477 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/26 (20130101) Optical Elements, Systems, or Apparatus G02B 6/0016 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/03 (20130101) Original (OR) Class G02F 1/21 (20130101) G02F 1/01708 (20130101) G02F 2202/32 (20130101) G02F 2203/12 (20130101) G02F 2203/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614751 | Alonso-Mora et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Javier Alonso-Mora (Leiden, Netherlands); Samitha Samaranayake (Brooktondale, New York); Alexander J. Wallar (Cambridge, Massachusetts); Daniela L. Rus (Weston, Massachusetts) |
| ABSTRACT | Described are concepts, systems, devices and techniques for real-time high-capacity ride-sharing that (i) scales to large numbers of passengers and trips and (ii) dynamically generates routes (e.g. optimal or near optimal routes) in response to online demand and vehicle locations. |
| FILED | Tuesday, January 23, 2018 |
| APPL NO | 15/877935 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/0291 (20130101) Original (OR) Class G05D 2201/0213 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614891 | Brewer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Tony Brewer (Plano, Texas) |
| ABSTRACT | Devices and techniques for communicating a programmable atomic operator to a memory controller are described herein. A memory controller can receive a memory request and extract a command indicator that indicates a programmable atomic operator (PAO) command from the memory request. The memory controller can then extract a PAO index from the request and invoke the PAO based on the PAO index. |
| FILED | Tuesday, October 20, 2020 |
| APPL NO | 17/074937 |
| ART UNIT | 2132 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0644 (20130101) G06F 3/0659 (20130101) Original (OR) Class G06F 3/0679 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614995 | Nelson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | David K. Nelson (Medicine Lake, Minnesota); Robert Rabe (Chanhassen, Minnesota); Keith Goike (Minneapolis, Minnesota) |
| ABSTRACT | A method for storing data includes determining, using a first match line, that a match word satisfies a first content addressable memory (CAM) word stored in a CAM array, wherein the CAM array is configured to store a second CAM word that matches the first CAM word. The method further includes determining that a first parity bit associated with the first CAM word matches a first parity of the first CAM word. The method further includes, in response to determining that the first parity bit associated with the first CAM word matches the first parity determining, using the first match line, a first random access memory (RAM) word stored in a RAM array and outputting the first RAM word. |
| FILED | Wednesday, October 13, 2021 |
| APPL NO | 17/450716 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1004 (20130101) Original (OR) Class Static Stores G11C 15/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11615221 | McMahon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew D. McMahon (Damascus, Maryland); Krzysztof J. Rutkowski (Riva, Maryland); Stephen M. Farley (Sterling, Virginia) |
| ABSTRACT | Exemplary practice of the present invention defines “sphibules” in computer-modeling the spread of a substance in a fluid medium. A “sphibule,” a modeling entity conceived and named by the present inventors, represents a discrete quantity of a substance that is propagative in a fluid medium. Every sphibule has the same size when created, the same constant geometric shape, the same constant mass, and a uniform density. Multiple sphibules are created at a prescribed rate at a source in the fluid medium. Several or many timesteps are performed to compute enlargement and relocation, in the fluid medium, of each sphibule that has been created. Through succeeding timesteps, each sphibule becomes less dense and more distant from the source. A sphibule ceases to exist when the sphibule is less dense than a prescribed minimum density of the sphibules, and/or when the sphibule travels beyond a prescribed spatial boundary of the fluid medium. |
| FILED | Thursday, May 08, 2014 |
| APPL NO | 14/272796 |
| ART UNIT | 2147 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11615318 | De La Houssaye et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul R. De La Houssaye (San Diego, California); Benjamin J. Migliori (Santa Fe, New Mexico); Adi Ratan Bulsara (San Diego, California); Chriswell Hutchens (San Diego, California); Justin M. Mauger (San Diego, California) |
| ABSTRACT | A pattern recognition device comprising: a coupled network of damped, nonlinear, dynamic elements configured to generate an output response in response to at least one environmental condition, wherein each element has an associated multi-stable potential energy function that defines multiple energy states of an individual element, and wherein the elements are tuned such that environmental noise triggers stochastic resonance between energy levels of at least two elements; a processor configured to monitor the output response over time and to determine a probability that the pattern recognition device is in a given state based on the monitored output response; and detecting a pattern in the at least one environmental condition based on the probability. |
| FILED | Friday, July 23, 2021 |
| APPL NO | 17/384338 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/214 (20230101) G06F 18/21355 (20230101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/088 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/955 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11615336 | Oliver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); SOCPRA SCIENCES ET GENIE S.E.C. (Sherbrooke, Canada) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | William D. Oliver (Arlington, Massachusetts); Simon Gustavsson (Cambridge, Massachusetts); Roni Winik (Somerville, Massachusetts); Catherine Leroux (Sainte Julie, Canada); Agustin Di Paolo (Sherbrooke, Canada); Alexandre Blais (Sherbrooke, Canada) |
| ABSTRACT | A quantum circuit called a “qumon” is provided to cancel unwanted ZZ interaction in a superconducting qubit architecture. The qumon qubit has a high coherence, and a positive anharmonicity that may be tuned to cancel the negative anharmonicity in a coupled qubit, such as a transmon qubit. The qumon has three parallel branches, in which are a shunt capacitor; a Josephson junction having weighted energy level and capacitance; and several Josephson junctions in series. The weight is chosen to provide the desired anharmonicity, and the transverse flux noise and transverse charge noise each decrease in proportion to the number of the Josephson junctions in series. Because unwanted ZZ interactions are canceled, qumon qubits and transmon qubits may be capacitively coupled in an alternating pattern to provide a surface code in which these interactions are canceled in an extensible way. |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/188461 |
| ART UNIT | 2896 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) H01L 39/223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616129 | Ma et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Zhenqiang Ma (Middleton, Wisconsin); Yei Hwan Jung (Seoul, South Korea) |
| ABSTRACT | Patterning methods for forming patterned device substrates are provided. Also provided are devices made using the methods. The methods utilize photoresist features have re-entrant profiles to form a secondary metal hard mask that can be used to pattern an underlying device substrate. |
| FILED | Wednesday, December 16, 2020 |
| APPL NO | 17/123453 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/283 (20130101) H01L 21/3086 (20130101) H01L 21/28114 (20130101) H01L 21/76885 (20130101) H01L 24/03 (20130101) H01L 24/05 (20130101) H01L 29/401 (20130101) H01L 29/778 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) H01L 29/42316 (20130101) H01L 29/42376 (20130101) Original (OR) Class H01L 29/66462 (20130101) H01L 2224/03472 (20130101) H01L 2224/05016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616184 | Strano et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael S. Strano (Lexington, Massachusetts); Anton Lee Cottrill (Cambridge, Massachusetts); Sayalee Girish Mahajan (Cambridge, Massachusetts); Tianxiang Liu (Cambridge, Massachusetts); Volodymyr B. Koman (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure is directed to materials, devices, and methods for resonant ambient thermal energy harvesting. Thermal energy can be harvested using thermoelectric resonators that capture and store ambient thermal fluctuations and convert the fluctuations to energy. The resonators can include non-linear heat transfer elements, such as thermal diodes, to enhance their performance. Incorporation of thermal diodes can allow for a dynamic rectification of temperature fluctuations into a single polarity temperature difference across a heat engine for power extraction, as compared to the dual polarity nature of the output voltage of linear thermal resonators, which typically necessitates electrical rectification to be routed to an entity for energy storage. In some embodiments, the thermal diode can be applied to transient energy harvesting to construct thermal diode bridges. Methods for constructing such devices, and using such devices, are also provided. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 16/120125 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/04 (20130101) F03G 7/06 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/02 (20130101) H01L 35/30 (20130101) Original (OR) Class H01L 35/32 (20130101) Electric Machines Not Otherwise Provided for H02N 11/002 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/44 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616246 | Ramani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vijay K. Ramani (St. Louis, Missouri); Zhongyang Wang (St. Louis, Missouri); Javier Parrondo (St. Louis, Missouri); Shrihari Sankarasubramanian (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Vijay K. Ramani (St. Louis, Missouri); Zhongyang Wang (St. Louis, Missouri); Javier Parrondo (St. Louis, Missouri); Shrihari Sankarasubramanian (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of method of inducing or providing a pH gradient in electrochemical or chemical systems. Briefly, the pH gradient is induced by use of coated particles or films with an ion exchange ionomer. |
| FILED | Tuesday, April 09, 2019 |
| APPL NO | 16/379212 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/083 (20130101) Original (OR) Class H01M 8/1004 (20130101) H01M 2300/0014 (20130101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616247 | Garsany et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Yannick Garsany (Severna Park, Maryland); Robert Atkinson, III (Winchester, Massachusetts); Benjamin Gould (Springfield, Virginia) |
| ABSTRACT | A fuel cell membrane electrode assembly having: a proton exchange membrane, an anode catalyst coating on one side of the membrane, and a cathode catalyst coating on the other side of the membrane. The cathode catalyst coating has at least two carbon catalyst layers, with a low porosity layer adjacent to a high porosity layer. The high porosity layers have a volume fraction that is higher than the volume fraction of the low porosity layers. |
| FILED | Wednesday, June 16, 2021 |
| APPL NO | 17/349464 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/926 (20130101) H01M 4/8605 (20130101) H01M 8/1004 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616300 | Bastin |
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| FUNDED BY |
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| APPLICANT(S) | Nantenna LLC (Melbourne, Florida) |
| ASSIGNEE(S) | Nantenna LLC (Melbourne, Florida) |
| INVENTOR(S) | Gary L. Bastin (Palm Bay, Florida) |
| ABSTRACT | The teachings of the present application generally provide a solution to one or more of the aforementioned needs by providing for a ultra-high frequency (UHF) antenna assembly which provides for a smaller package size with the same or better efficiency as a much larger antenna, particularly at 100 MHz to 500 MHz. Particularly, through the combination of components and structures for implementing frequency selective surfaces (FSS) and high impedance structures (HIS) in combination with an anisotropic magneto-dielectric material, the present teachings provide for the use of both lower and higher frequency techniques at 200 MHz to 400 MHz frequency range and miniaturization, accurately improving the performance of UHF satellite communication antennas. Specifically improving performance in narrowband, with increases in efficiency, bandwidth, and lowered elevation angle radiation characteristics. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/671915 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/48 (20130101) H01Q 1/523 (20130101) H01Q 5/22 (20150115) Original (OR) Class H01Q 5/357 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616341 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Hui Cao (New Haven, Connecticut); Stefan Wolfgang Bittner (Metz, France); Kyungduk Kim (New Haven, Connecticut) |
| ABSTRACT | Exemplary embodiments of the present disclosure include chip-scale laser sources, such as semiconductor laser sources, that produce directional beams with low spatial coherence. The lasing modes are based on the axial orbit in a stable cavity and have good directionality. To reduce the spatial coherence of emission, the number of transverse lasing modes can be increased by fine-tuning the cavity geometry. Decoherence is reached in as little as several nanoseconds. Such rapid decoherence facilitates applications in ultrafast speckle-free full-field imaging. |
| FILED | Friday, July 24, 2020 |
| APPL NO | 16/937985 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/48 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/06817 (20130101) H01S 5/18386 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616378 | Kuznetsov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Stephen Kuznetsov (Marlboro, Massachusetts) |
| ABSTRACT | A power transfer system includes a series of energy storage modules (ESMs) or energy storage devices (ESDs) that are coupled together to be able to transfer power between one another, as well as receive power from a power source, such as an onshore power generator. The energy storage modules may be hybrid energy storage modules, each including an electrical-machine-inertial energy store and an electro-chemical energy store. The energy storage modules are configured to receive constant-current DC or AC input from the power source, and are able to provide constant-current and constant-voltage output, either sequentially or simultaneously. The power transfer system allows the modules to operate independently or in conjunction with one another, should some of the connections of the system be broken. The energy storage modules may be used to provide power to underwater systems, for example sonar systems, weapons systems, or underwater vehicles. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/437750 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/46 (20130101) H01M 12/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/30 (20130101) H02J 3/322 (20200101) H02J 7/0024 (20130101) Original (OR) Class H02J 7/345 (20130101) Dynamo-electric Machines H02K 7/025 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/217 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/007 (20130101) Transmission H04B 13/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616477 | Wagner et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Eric C. Wagner (Redondo Beach, California); Timothy R. LaRocca (Torrance, California) |
| ABSTRACT | A radio frequency (RF) summer circuit having a characteristic impedance Zo comprises first and second ports coupled by first and second resistances, respectively, to a junction. The circuit further comprises a series combination of a third resistance and a switch movable between open and closed positions and an amplifier having input and output terminals and operable in an off state and an on state wherein the series combination is coupled across the input and output terminals of the amplifier between the junction and a third port. The first resistance, second resistance, and the third resistance are all substantially equal to Z0/3. Further, when the switch is moved to the closed position and the amplifier is switched to the off state a passive mode of operation is implemented and when the switch is moved to the open position and the amplifier is switched to the on state an active mode of operation is implemented. The RF summer circuit develops a summed signal at the third port equal to a sum of signals at the first and second ports modified by one of first and second gain values. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/126756 |
| ART UNIT | 2843 — Electrical Circuits and Systems |
| CURRENT CPC | Amplifiers H03F 1/56 (20130101) H03F 3/72 (20130101) H03F 3/195 (20130101) Original (OR) Class H03F 2200/451 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11612586 | Alaniz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Robert C. Alaniz (College Station, Texas); Arul Jayaraman (College Station, Texas); Kyongbum Lee (Winchester, Massachusetts) |
| ABSTRACT | The disclosure provides methods and compositions for affecting the development of antigen presenting cell (APC, e.g., a macrophage or dendritic cell). The methods include maturing an APC, promoting anti-inflammatory phenotype, promoting development of a T regulatory cell (Treg) from a naive T cell. The methods generally include exposing an APC to a tryptophan derived microbiota metabolite (TDMM), such as an anti-inflammatory or pro-mucosal TDMM, and permitting the APC to mature. In some embodiments, the conditioned APC is exposed to a naive T cell to further promote development of a T regulatory cell (Treg). In some embodiments, the TDMM is selected from the group consisting of indole, indole-3-acetate, 5-hydroxyindole, and indole-3-pyruvate. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 16/085912 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/405 (20130101) Original (OR) Class A61K 31/475 (20130101) A61K 31/7004 (20130101) A61K 35/17 (20130101) A61K 45/06 (20130101) A61K 2035/122 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 29/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/064 (20130101) C12N 5/0636 (20130101) C12N 5/0637 (20130101) C12N 2501/15 (20130101) C12N 2501/24 (20130101) C12N 2501/51 (20130101) C12N 2501/515 (20130101) C12N 2501/999 (20130101) C12N 2501/2301 (20130101) C12N 2501/2304 (20130101) C12N 2501/2306 (20130101) C12N 2501/2312 (20130101) C12N 2501/2321 (20130101) C12N 2501/2323 (20130101) C12N 2502/1121 (20130101) C12N 2502/1157 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613502 | Bartel et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Christopher Bartel (Boulder, Colorado); Alan W. Weimer (Niwot, Colorado); Rebecca Jean O'Toole (Boulder, Colorado); Maila Kodas (Carlisle, Massachusetts) |
| ABSTRACT | Disclosed herein is a ceramic particle comprising a core substrate chosen from yttria-stabilized zirconia, partially stabilized zirconia, zirconium oxide, aluminum nitride, silicon nitride, silicon carbide, and cerium oxide, and a conformal coating of a sintering aid film having a thickness of less than three nanometers and covering the core substrate, and methods for producing the ceramic particle. |
| FILED | Saturday, November 04, 2017 |
| APPL NO | 16/347585 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/624 (20130101) C04B 35/4885 (20130101) Original (OR) Class C04B 35/62813 (20130101) C04B 2235/3217 (20130101) C04B 2235/3246 (20130101) C04B 2235/6026 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1253 (20130101) H01M 2008/1293 (20130101) H01M 2300/0077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613603 | Hearon et al. |
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| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Keith Hearon (College Station, Texas); Landon D. Nash (College Station, Texas); Thomas Wilson (Livermore, California); Duncan J. Maitland (College Station, Texas); Mark A. Wierzbicki (College Station, Texas) |
| ABSTRACT | An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein. |
| FILED | Thursday, July 09, 2020 |
| APPL NO | 16/924819 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/675 (20130101) C08G 18/758 (20130101) C08G 18/3206 (20130101) Original (OR) Class C08G 18/3212 (20130101) C08G 18/6715 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/16 (20130101) C08L 81/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613648 | Rangari et al. |
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| FUNDED BY |
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| APPLICANT(S) | TUSKEGEE UNIVERSITY (Tuskegee, Alabama) |
| ASSIGNEE(S) | TUSKEGEE UNIVERSITY (Tuskegee, Alabama) |
| INVENTOR(S) | Vijaya Rangari (Tuskegee, Alabama); Boniface Tiimob (Tuskegee, Alabama) |
| ABSTRACT | A biopolymer blend is provided that comprises a combination of three components: poly (butylene adipate-co-terephthalate) (PBAT); agriculture sourced polylactic acid (PLA); and engineered proteinaceous eggshell nanoparticles. The two polymer components can be present in any ratio but an approximate 70:30 ratio is preferred. The engineered proteinaceous eggshell nanoparticles are preferably about 10-25 nanometers. Also provided are methods of preparing biopolymer film and packaging components. Pelleted poly (butylene adipate-co-terephthalate) and agriculture sourced polylactic acid (PLA) are dissolved in chloroform and mixed together to form a polymer blend, and engineered proteinaceous eggshell nanoparticles are incorporated into the polymer blend, which is then extruded to create a biopolymer film or component. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/393315 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/11 (20130101) C08J 3/14 (20130101) C08J 3/093 (20130101) C08J 3/212 (20130101) C08J 3/215 (20130101) C08J 5/18 (20130101) C08J 2367/02 (20130101) C08J 2467/04 (20130101) C08J 2489/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/00 (20130101) C08K 7/00 (20130101) C08K 2201/005 (20130101) C08K 2201/011 (20130101) C08K 2201/018 (20130101) Compositions of Macromolecular Compounds C08L 67/02 (20130101) C08L 67/04 (20130101) Original (OR) Class C08L 77/00 (20130101) C08L 89/00 (20130101) C08L 2201/06 (20130101) C08L 2203/16 (20130101) C08L 2205/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613653 | Delcamp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Mississippi (University, Mississippi) |
| ASSIGNEE(S) | UNIVERSITY OF MISSISSIPPI (University, Mississippi) |
| INVENTOR(S) | Jared Heath Delcamp (Oxford, Mississippi); Roberta Ramalho Rodrigues (Oxford, Mississippi); Adithya Peddapuram (Oxford, Mississippi); Hammad Arshad Cheema (Lahore, Pakistan) |
| ABSTRACT | Provided herein are dyes, dye-sensitized solar cells, and sequential series multijunction dye-sensitized solar cell devices. The dyes include an electron deficient acceptor moiety, a medium electron density ?-bridge moiety, and an electron rich donor moiety comprising a biaryl, a substituted biaryl, or an R1, R2, R3 substituted phenyl where each of R1, R2, and R3 independently comprises H, aryl, multiaryl, alkyl substituted aryl, alkoxy substituted aryl, alkyl substituted multiaryl, alkoxy substituted multiaryl, OR4, N(R5)2, or a combination thereof; each R4 independently comprises H, alkyl, aryl, alkyl substituted aryl, alkoxy substituted aryl, or a combination thereof; and each R5 independently comprises aryl, multiaryl, alkyl substituted aryl, alkoxy substituted aryl, alkyl substituted multiaryl, alkoxy substituted multiaryl, or a combination thereof. The solar cells include a glass substrate, a dye-sensitized active layer, and a redox shuttle. The devices include at least two dye-sensitized solar cells connected in series. |
| FILED | Thursday, July 26, 2018 |
| APPL NO | 16/634050 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 11/04 (20130101) Original (OR) Class C09B 57/004 (20130101) C09B 69/008 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2018 (20130101) H01G 9/2063 (20130101) H01G 9/2072 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0067 (20130101) H01L 51/0069 (20130101) H01L 51/0074 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613674 | Sitti et al. |
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| FUNDED BY |
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| APPLICANT(S) | nanoGriptech, Inc. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Setex Technologies, Inc. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Metin Sitti (Pittsburgh, Pennsylvania); Burak Aksak (Lubbock, Texas) |
| ABSTRACT | This invention identifies important geometric parameters of an adhesive microfiber with mushroom-shaped tip for improving and optimizing adhesive ability. The magnitude of pull-off stress is dependent on a wedge angle γ and the ratio of the tip radius to the stalk radius β of the mushroom-shaped fiber. Pull-off stress is also found to depend on a dimensionless parameter x, the ratio of the fiber radius to a length-scale related to the dominance of adhesive stress. Finally, the shape of edge tip, where the surface and sides of the mushroom-shaped tip join, is a factor that impacts strength of adhesion. Optimizing ranges for these parameters are identified. |
| FILED | Tuesday, June 02, 2020 |
| APPL NO | 16/890204 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/00 (20130101) Original (OR) Class C09J 9/00 (20130101) C09J 2301/31 (20200801) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/20 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/10 (20130101) D10B 2401/06 (20130101) D10B 2403/0114 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2976 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613695 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Jing Li (Cranbury, New Jersey); Wei Liu (New Brunswick, New Jersey); Kun Zhu (Piscataway, New Jersey) |
| ABSTRACT | Inorganic-organic hybrid structures having both ionic and coordinate bonds in a molecular cluster possessing the features of structural diversity, high luminescence and stability, and excellent dispersibility, suitable for use as lighting phosphors. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 16/610712 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 2211/188 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/60 (20130101) H01L 33/502 (20130101) H01L 51/0091 (20130101) H01L 2933/0041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613782 | Suliman et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CAPE TOWN (Cape Town, South Africa); STELLENBOSCH UNIVERSITY (Cape Town, South Africa); SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington); MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V (Munich, Germany); UNITED KINGDOM RESEARCH AND INNOVATION (Swindon, United Kingdom) |
| ASSIGNEE(S) | UNIVERSITY OF CAPE TOWN (Cape Town, South Africa); STELLENBOSCH UNIVERSITY (Cape Town, South Africa); SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington); MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V (Munich, Germany); UNITED KINGDOM RESEARCH AND INNOVATION (Swindon, United Kingdom) |
| INVENTOR(S) | Sara Suliman (Brookline, Massachusetts); Ethan Greene Thompson (Seattle, Washington); Jayne Suzanne Sutherland (Banjul, Gambia); Stefan H. E. Kaufmann (Berlin, Germany); Thomas Jens Scriba (Cape Town, South Africa); Daniel Edward Zak (Seattle, Washington); Gerhard Walzl (Cape Town, South Africa) |
| ABSTRACT | The invention provides a gene signature for use in determining a likelihood of a latent tuberculosis (TB) infection in a subject transitioning to active TB disease. The gene signature comprises at least SEPT4 and BLK, and optionally also GAS6 and/or CD1C. Expression levels of these genes are detected in a sample from the subject, and the ratios of expression of at least two of the above genes are calculated (e.g. SEPT4:BLK, SEPT4:CD1C, GAS6:BLK and/or GAS6:CD1C). A score is assigned to each ratio, the score being indicative of the likelihood of the latent TB infection transitioning into active TB disease, based on the ratio for the respective gene pair. The subject can be identified as having a latent TB infection that is likely to transition into active TB disease or that is not likely to transition into active TB disease based on the score or on the average of the scores. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/980121 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613807 | Maschmann et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Matthew R. Maschmann (Columbia, Missouri); Matthias J. Young (Columbia, Missouri) |
| ABSTRACT | A method of depositing a nanoscale-thin film onto a substrate is disclosed. The method generally comprises depositing a layer of a solid or gaseous state functionalizing molecule onto or adjacent to the first surface of the substrate and exposing the first surface to a source of ionizing radiation, thereby functionalizing the first surface of the substrate. Once the layer of functionalizing molecule is removed, a nanoscale-thin film is then deposited onto the functionalized first surface of the substrate. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387185 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/20 (20130101) C23C 16/0263 (20130101) Original (OR) Class C23C 16/403 (20130101) C23C 16/45527 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614501 | Javor et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Joshua Javor (Cambridge, Massachusetts); David Bishop (Brookline, Massachusetts); David Campbell (Brookline, Massachusetts); Matthias Imboden (St. Blaise, Switzerland) |
| ABSTRACT | A gradiometer includes a at least one magnet attached to a beam. The magnet moves in response to a magnetic force. A sensing element is configured to measure movement or deflection of the beam or magnet. The gradiometer is configured to determine a gradient of a magnetic field acting on the first magnet based on movement of the magnet. The gradiometer can further measure higher order gradients. |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/692692 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/022 (20130101) Original (OR) Class G01R 33/038 (20130101) G01R 33/0052 (20130101) G01R 33/0385 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614823 | Do et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Brian H. Do (Plant City, Florida); Allison M. Okamura (Mountain View, California); Laura H. Blumenschein (Lafayette, Indiana) |
| ABSTRACT | A macro-mini actuation mechanism for pneumatic pouches is provided which involves stacking smaller proximal pouches (proximal layer) underneath larger distal pouches (distal layer). The proximal layer of smaller pouches is the contact area with e.g. a (human) body. Macro-mini pneumatic actuation of pouches for wearable haptic displays allows for the control of contact area of pneumatic pouches and the ability to cover large areas while maintaining a fast-dynamic response and higher spatial resolutions. This stacked pouch concept allows for pressure/force feedback to a user—something which cannot be rendered by vibrotactile actuators alone. Control of effective pouch height may also allow a potential wearable haptic display to better conform to the human body. A pressure-based display with stacked pouches could allow for larger tolerances between the display and the human body without sacrificing contact area, allowing better fit across users. |
| FILED | Monday, April 11, 2022 |
| APPL NO | 17/718043 |
| ART UNIT | 2627 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/016 (20130101) G06F 3/0416 (20130101) Original (OR) Class Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11615266 | Faller |
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| FUNDED BY |
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| APPLICANT(S) | Perceptive Automata Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | PERCEPTIVE AUTOMATA, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Avery Wagner Faller (Boston, Massachusetts) |
| ABSTRACT | A vehicle collects video data of an environment surrounding the vehicle including traffic entities, e.g., pedestrians, bicyclists, or other vehicles. The captured video data is sampled and presented to users to provide input on a traffic entity's state of mind. The user responses on the captured video data is used to generate a training dataset. A machine learning based model configured to predict a traffic entity's state of mind is trained with the training dataset. The system determines input video frames and associated dimension attributes for which the model performs poorly. The dimension attributes characterize stimuli and/or an environment shown in the input video frames. The system generates a second training dataset based on video frames that have the dimension attributes for which the model performed poorly. The model is retrained using the second training dataset and provided to an autonomous vehicle to assist with navigation in traffic. |
| FILED | Tuesday, October 27, 2020 |
| APPL NO | 17/081211 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/0221 (20130101) G05D 2201/0213 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6254 (20130101) Original (OR) Class G06K 9/6256 (20130101) G06K 9/6262 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image or Video Recognition or Understanding G06V 20/56 (20220101) G06V 40/10 (20220101) G06V 2201/08 (20220101) Traffic Control Systems G08G 1/0112 (20130101) G08G 1/0125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616299 | Gómez-Diaz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Juan Sebastián Gómez-Diaz (Davis, California); Diego Correas Serrano (Phoenix, Arizona); Alejandro Álvarez-Melcón (Cartagena, Spain); Jiawei Zang (Beijing, China PRC) |
| ABSTRACT | The disclosed embodiments relate to the design of a system that implements a reflectarray antenna. The system includes a time-modulated metasurface, which is configured to act as a planar reflector for an electromagnetic wave that is radiated by a feeder into free space at an operation frequency f0. The time-modulated metasurface includes time-modulated unit-cells that provide a nonlinear conversion between f0 and another desired frequency fd. The system also includes a phase-delay mechanism, which adjusts a phase delay by acting on a phase applied to a modulation frequency fm that modulates each unit-cell. The nonlinear conversion and the phase-delay mechanism operate collectively to facilitate angle-independent nonreciprocity by imposing different phase gradients during up-conversion and down-conversion processes, and by preventing generation of certain propagative harmonics due to total internal reflection. |
| FILED | Monday, December 16, 2019 |
| APPL NO | 16/715520 |
| ART UNIT | 2849 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 1/288 (20130101) H01Q 3/22 (20130101) H01Q 3/36 (20130101) H01Q 3/46 (20130101) Original (OR) Class H01Q 9/0457 (20130101) H01Q 15/148 (20130101) H01Q 21/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE49474 | Golkowski |
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| FUNDED BY |
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| APPLICANT(S) | STERIFRE MEDICAL, INC. (Kirkland, Washington) |
| ASSIGNEE(S) | Sterifre Medical, Inc. (Kirkland, Washington) |
| INVENTOR(S) | Czeslaw Golkowski (Ithaca, New York) |
| ABSTRACT | A free radical sterilization system having a chamber defining a region, and a generator for generating free radical reach effluent from a free radical electric generator and/or a vaporizer. A closed loop circulating system without a free-radical destroyer is provided for supplying the mixture of free radicals from the electric generator mixed with the hydrogen peroxide solution in the form of the effluent to the chamber. The free-radical sterilization system is used in sterilizing items in the chamber and, with an open-bottomed wound chamber, in treating wounds on a body. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 16/542205 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0294 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/00 (20130101) Original (OR) Class A61L 2/22 (20130101) A61L 2/186 (20130101) A61L 2/208 (20130101) A61L 9/00 (20130101) A61L 9/03 (20130101) A61L 9/015 (20130101) A61L 11/00 (20130101) A61L 2202/11 (20130101) A61L 2202/14 (20130101) A61L 2202/15 (20130101) A61L 2202/26 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/69 (20210501) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 12/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11612899 | Siler et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | David Michael Siler (Albuquerque, New Mexico); Michael Edward Ferdinand (Placitas, New Mexico) |
| ABSTRACT | A method for isolating vibrations for centrifuge testing devices is provided. The method comprises coupling a test payload platform to a number of piezoelectric actuators and coupling the piezoelectric actuators to a reaction mass coupled to a centrifuge arm. A layer of vibration-absorbing material is sandwiched between the reaction mass and the centrifuge arm. The centrifuge arm is rotated around an axis, and the test payload platform is vibrated with the piezoelectric actuators as the centrifuge rotates, wherein the layer of vibration-absorbing material prevents vibrations from traveling down the centrifuge arm. |
| FILED | Monday, March 15, 2021 |
| APPL NO | 17/202158 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Centrifuges B04B 5/10 (20130101) Original (OR) Class Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0629 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 15/08 (20130101) F16F 2234/02 (20130101) F16F 2234/06 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 7/022 (20130101) G01M 7/027 (20130101) G01M 99/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613603 | Hearon et al. |
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| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Keith Hearon (College Station, Texas); Landon D. Nash (College Station, Texas); Thomas Wilson (Livermore, California); Duncan J. Maitland (College Station, Texas); Mark A. Wierzbicki (College Station, Texas) |
| ABSTRACT | An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein. |
| FILED | Thursday, July 09, 2020 |
| APPL NO | 16/924819 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/73 (20130101) C08G 18/675 (20130101) C08G 18/758 (20130101) C08G 18/3206 (20130101) Original (OR) Class C08G 18/3212 (20130101) C08G 18/6715 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/16 (20130101) C08L 81/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613649 | Freeman et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Benny D. Freeman (Austin, Texas); Donald R. Paul (Austin, Texas); Joshua D. Moon (Austin, Texas) |
| ABSTRACT | Polymer blends comprising an ortho-functionalized polyimide homo or copolymer and a polybenzimidazole homo or copolymer, wherein the ortho-functionalized polyimide thermally rearranges to a polymer comprising a phenylene heterocyclic group, such as, polybenzoxazole, polybenzothiazole, polybenzimidazole and/or other heterocyclic structure upon heating. Also disclosed are method of forming a polymer blend comprising dissolving an ortho-functionalized polyimide homo or copolymer and a polybenzimidazole homo or copolymer in a solvent, and optional compatibilizer, to form a polymer solution; contacting a support with the polymer solution; and evaporating the solvent to provide a thin layer comprising the polymer blend on the support. Further, methods of heat treating these polymer blends to thermally rearrange the disclosed polyimides are disclosed, as are the polymer blends prepared thereby. Methods of using these polymer blends to separate gases are also disclosed. |
| FILED | Tuesday, April 02, 2019 |
| APPL NO | 17/044540 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 53/268 (20130101) B01D 67/0013 (20130101) B01D 67/0018 (20130101) B01D 69/12 (20130101) B01D 71/64 (20130101) Compositions of Macromolecular Compounds C08L 79/08 (20130101) Original (OR) Class C08L 2207/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613691 | Pollock |
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| FUNDED BY |
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| APPLICANT(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| ASSIGNEE(S) | OCEANIT LABORATORIES, INC. (Honolulu, Hawaii) |
| INVENTOR(S) | Jacob Pollock (Honolulu, Hawaii) |
| ABSTRACT | Deployable smart acoustic resonance particles have dense cores, compliant matrixes surrounding the cores and stiff outer shells surrounding the matrixes. The particles have mechanical stress sensitivities that provide unique band gap shifts when compressed. Groups of similar particles with similar stress sensitivities and similar band gap shifts are added at different times to hydraulic fluids, as circulated through wells with the fluid and pushed into fractures. A plural, sonic monopole well logging tool is lowered into the well to determine locations and depth of fractures and local pressures by distinct resonance of individual groups. |
| FILED | Tuesday, December 31, 2019 |
| APPL NO | 16/731732 |
| ART UNIT | 3619 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/805 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/267 (20130101) E21B 47/095 (20200501) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/46 (20130101) G01V 2210/14 (20130101) G01V 2210/123 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613760 | Oikawa |
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| FUNDED BY |
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| APPLICANT(S) | AFINGEN, INC. (Emeryville, California) |
| ASSIGNEE(S) | AFINGEN, INC. (Emeryville, California) |
| INVENTOR(S) | Ai Oikawa (Emeryville, California) |
| ABSTRACT | The present invention relates to transgenic plants with vascular xylem tissue-targeting overexpression of tissue factors involved in vascular xylem cell development. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/965809 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8223 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613823 | Willit et al. |
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| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | James L. Willit (Batavia, Illinois); Magdalena M. Tylka (Willow Springs, Illinois); Mark A. Williamson (Naperville, Illinois); Stanley G. Wiedmeyer (Glen Ellyn, Illinois); Javier Figueroa (Andover, Kansas) |
| ABSTRACT | A method for recycling molten salt from electrorefining processes, the method having the steps of collecting actinide metal using a first plurality of cathodes from an electrolyte bath, collecting rare earths metal using a second plurality of cathodes from the electrolyte bath, inserting the collected actinide metal and uranium into the bath, and chlorinating the inserted actinide metal and uranium. Also provided is a system for recycling molten salt, the system having a vessel adapted to receive and heat electrolyte salt, a first plurality of cathodes adapted to be removably inserted into the vessel, a second plurality of cathodes adapted to be removably inserted into the vessel, an anode positioned within the vessel so as to be coaxially aligned with the vessel, and a vehicle for inserting uranium into the salt. |
| FILED | Monday, December 23, 2019 |
| APPL NO | 16/724705 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 3/34 (20130101) Original (OR) Class C25C 7/005 (20130101) C25C 7/06 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613825 | Hubbard et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Lance Hubbard (Richland, Washington); Christina Arendt (Richland, Washington); Ryan Webster (Spokane Valley, Washington) |
| ABSTRACT | Disclosed herein are embodiments of a coating composition and a method of using the same for forming metal coatings on substrates. In particular embodiments, the coating composition comprises a deep eutectic solvent and/or an ionic liquid; a metal precursor; an alkali metal salt; and an optional additive component. The coating composition and method embodiments disclosed herein provide durable, even, high-surface area coatings on various types of substrates and also can be used at low temperatures. |
| FILED | Wednesday, May 27, 2020 |
| APPL NO | 16/884999 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/54 (20130101) Original (OR) Class C25D 5/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614233 | Berry et al. |
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| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Jonathan Dwight Berry (Simpsonville, South Carolina); Jerome Walter Goike (Greenville, South Carolina); Clay Thomas Griffis (Greenville, South Carolina) |
| ABSTRACT | An integrated combustor nozzle includes a combustion liner that extends between an inner liner segment and an outer liner segment along a radial direction. The combustion liner including a forward end portion, an aft end portion, a first side wall, and a second side wall. An impingement panel having an impingement plate disposed along an exterior surface of one of the inner liner segment or the outer liner segment. The impingement plate defines a plurality of impingement apertures that direct coolant in discrete jets towards the exterior surface of the inner liner segment or the outer liner segment. The impingement panel includes an inlet portion that extends from the impingement plate to a collection duct. The impingement panel further includes a plurality of supports spaced apart from one another. The plurality of supports extend between, and are coupled to, the inlet portion, the collection duct, and the impingement plate. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/007108 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/201 (20130101) F05D 2260/22141 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) Original (OR) Class F23R 3/283 (20130101) F23R 2900/03044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614534 | Beer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | N. Reginald Beer (Pleasanton, California); Steven Bond (Livermore, California); Peter C. Haugen (Livermore, California); Jacob Trueblood (Dublin, California); Brian Matthew Wihl (Pleasanton, California) |
| ABSTRACT | A GPR system the implements a modified multistatic mode of operation is provided. The GPR is suitable for mounting on an unmanned aerial vehicle. The GPR system has radar transceivers. The GPR system transmits transmit signal serially via the transceivers. For each transceiver that transmits a transmit signal, the GPR system receives a return signal acquired by each transceiver except for a return signal for the transceiver that transmits the transmit signal. The GPR system outputs of matrix of return signals that includes a null value for the return signals of the transceivers that transmit. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 16/779339 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/003 (20130101) G01S 13/87 (20130101) G01S 13/89 (20130101) G01S 13/0209 (20130101) G01S 13/885 (20130101) Original (OR) Class Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616158 | Zhu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Shanghai Jiao Tong University (Minhang, China PRC) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Kai Zhu (Littleton, Colorado); Yixin Zhao (Shanghai, China PRC); Mengjin Yang (Lakewood, Colorado); Taiyang Zhang (Shanghai, China PRC) |
| ABSTRACT | Methods are described that include contacting an alkyl ammonium metal halide film with an alkyl ammonium halide, where the alkyl ammonium metal halide film includes a first halogen and a metal, the alkyl ammonium halide includes a second halogen, such that the contacting forms an alkyl ammonium metal mixed-halide film that interfaces with the alkyl ammonium metal halide film, where the alkyl ammonium metal mixed-halide film includes the first halogen, the second halogen, and the metal. |
| FILED | Monday, May 11, 2020 |
| APPL NO | 16/871406 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 15/043 (20130101) B32B 2307/202 (20130101) B32B 2311/14 (20130101) B32B 2311/16 (20130101) B32B 2457/12 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) C01P 2002/72 (20130101) C01P 2004/03 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/24 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/055 (20130101) Original (OR) Class H01L 31/0256 (20130101) H01L 51/0003 (20130101) H01L 51/0032 (20130101) H01L 51/4226 (20130101) H01L 2031/0344 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11613504 | Brogden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Michael Brogden (Galloway, New Jersey); Steve Duffy (Hammonton, New Jersey) |
| ABSTRACT | An explosive sheet simulant that uses an ethylene vinyl acetate polymer combined with boron carbide or iron oxide for X-ray attenuating properties, and components of the mixture selected for predetermined flexural modulus combined with particle density, effective atomic number, X-ray transmission properties, or millimeter wave properties. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/583983 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/001 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/38 (20130101) C08K 3/38 (20130101) C08K 2003/265 (20130101) C08K 2003/2244 (20130101) C08K 2003/2265 (20130101) Compositions of Macromolecular Compounds C08L 23/0853 (20130101) C08L 23/0853 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613537 | Zang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Ling Zang (Salt Lake City, Utah); Paul Slattum (Salt Lake City, Utah) |
| ABSTRACT | Methods of detecting a non-explosive analyte can include exposing a sensor compound to a non-explosive analyte and displaying a change in the sensor compound upon exposure of the sensor compound to the non-explosive analyte. A variety of sensor compounds for detecting a target analyte, including both explosive and non-explosive analytes, is also described. Sensor devices for detecting a target analyte can include a substrate and a sensor compound positioned on the substrate in a plurality of detection zones. |
| FILED | Tuesday, March 31, 2020 |
| APPL NO | 16/835735 |
| ART UNIT | 1796 — Organic Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Heterocyclic Compounds C07D 221/18 (20130101) C07D 471/04 (20130101) Original (OR) Class C07D 491/052 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/643 (20130101) G01N 27/126 (20130101) G01N 2021/6432 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614544 | Taylor, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Setter Research, Inc. (Greensboro, North Carolina) |
| ASSIGNEE(S) | Setter Research, Inc. (Greensboro, North Carolina) |
| INVENTOR(S) | David W. A. Taylor, Jr. (Greensboro, North Carolina) |
| ABSTRACT | Disclosed herein are methods, devices, and systems for determining geographic location and time. In one embodiment, a radio and a processor configured for deriving a first signal tone originating from a first remote antenna located at a first location; deriving a second signal tone originating from a second remote antenna located at a second location; deriving a third signal tone originating from a third remote antenna located at a third location; determining a first frequency and a first phase at a first time of the first signal tone; determining a second frequency and a second phase at a second time of the second signal tone; and determining a third frequency and a third phase at a third time of the third signal tone. The method further includes determining a geographic location based on the first, second, and third frequencies; the first, second, and third phases; and the first, second, and third locations. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/412325 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/25 (20130101) Original (OR) Class G01S 19/26 (20130101) G01S 19/243 (20130101) Wireless Communication Networks H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614559 | Atherton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | Eric Atherton (Middletown, New Jersey); Matthew Aderholdt (Vineland, New Jersey); Joseph Regensburger (Grove City, Ohio); Lucinda Flaherty (Bradenton, Florida); Joseph Cochran (Egg Harbor Township, New Jersey) |
| ABSTRACT | A dosimeter assembly being placed within an inner volume of a test article for evaluating an image produced by an x-ray computed tomography (CT) system. The dosimeter assembly includes: a dosimeter having a display, a dosimeter shelf that supports the dosimeter; and an alignment bracket that positions the dosimeter on the dosimeter shelf. The dosimeter shelf is operable to be mounted within the x-ray computed tomography system test article, and the display of the dosimeter is viewable through a dosimeter window which is disposed at a front end of the x-ray computed tomography system test article, wherein the dosimeter assembly is accessible through an access panel directly beneath the dosimeter assembly, the access panel being an opening which is disposed on a base of the x-ray computer tomography system test article. The dosimeter is operably connected to a connection interface which is configured to exchange communication with an external device. |
| FILED | Thursday, October 22, 2020 |
| APPL NO | 17/078028 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/02 (20130101) G01T 7/005 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/005 (20130101) Original (OR) Class G01V 5/0008 (20130101) G01V 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11613349 | North et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | David D. North (Williamsburg, Virginia); Michael P. Hendrickson (Hampton, Virginia); Joshua C. Glaab (Hampton, Virginia) |
| ABSTRACT | The presently disclosed embodiments relate to vertical takeoff and landing (VTOL) aircraft that have the capability of hovering in both a “nose forward” and a “nose up” orientation, and any orientation between those two. The disclosed aircraft can also transition into wing born (non-hovering) flight from any of the hovering orientations. In addition, certain of the disclosed embodiments can, if desired, use only vectored thrust control to maintain stable flight in both hover and forward flight. No control surfaces (e.g. ailerons, elevators, rudders, flaps) are required to maintain a stable vehicle attitude. However, the disclosure contemplates aircraft both with and without such control surfaces. |
| FILED | Tuesday, May 25, 2021 |
| APPL NO | 17/329853 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 11/46 (20130101) B64C 11/48 (20130101) B64C 29/0033 (20130101) Original (OR) Class B64C 29/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11613760 | Oikawa |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AFINGEN, INC. (Emeryville, California) |
| ASSIGNEE(S) | AFINGEN, INC. (Emeryville, California) |
| INVENTOR(S) | Ai Oikawa (Emeryville, California) |
| ABSTRACT | The present invention relates to transgenic plants with vascular xylem tissue-targeting overexpression of tissue factors involved in vascular xylem cell development. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/965809 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8223 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614331 | Seah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CHEVRON U.S.A. INC. (San Ramon, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | Chevron U.S.A. Inc. (San Ramon, California); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Robert Kwan Meng Seah (Cypress, Texas); Hailing An (Houston, Texas); Darmindra Arumugam (Pasadena, California) |
| ABSTRACT | Magneto-electric quasistatic (MEQS) field may be used to track positions of persons and/or objects inside metallic environments. A magneto-electric quasistatic field generator may generate a magneto-electric quasistatic field inside a metallic environment. A magneto-electric quasistatic field detector inside the metallic environment may detect the magneto-electric quasistatic field and generate output signals conveying characteristics of the magneto-electric quasistatic field. The relative position of the magneto-electric quasistatic field detector with respect to the magneto-electric quasistatic field generator may be determined based on the output signals. The position of the magneto-electric quasistatic field detector/generator and/or the position of a person/object carrying the magneto-electric quasistatic field detector/generator may be tracked using the relative position of the magneto-electric quasistatic field detector with respect to the magneto-electric quasistatic field generator. |
| FILED | Wednesday, November 04, 2020 |
| APPL NO | 17/089496 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/206 (20130101) Original (OR) Class G01C 21/1654 (20200801) Wireless Communication Networks H04W 4/029 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616574 | Velazco |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Jose E. Velazco (Pasadena, California) |
| ABSTRACT | Optical ground terminals (OGT) allowing high optical rate communications for line of sight and non-line of sight operating conditions are disclosed. The described devices include a multifaceted structure where optical telescopes, phase array antennas, and arrays of optical detectors are disposed. Methods to calculate angle-of-arrival based the contributions from optical detectors are also disclosed. |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/184446 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/48 (20130101) Optical Elements, Systems, or Apparatus G02B 26/0816 (20130101) G02B 27/30 (20130101) Antennas, i.e Radio Aerials H01Q 3/2676 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/042 (20130101) Transmission H04B 10/25 (20130101) H04B 10/50 (20130101) H04B 10/118 (20130101) Original (OR) Class H04B 10/616 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11613674 | Sitti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | nanoGriptech, Inc. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Setex Technologies, Inc. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Metin Sitti (Pittsburgh, Pennsylvania); Burak Aksak (Lubbock, Texas) |
| ABSTRACT | This invention identifies important geometric parameters of an adhesive microfiber with mushroom-shaped tip for improving and optimizing adhesive ability. The magnitude of pull-off stress is dependent on a wedge angle γ and the ratio of the tip radius to the stalk radius β of the mushroom-shaped fiber. Pull-off stress is also found to depend on a dimensionless parameter x, the ratio of the fiber radius to a length-scale related to the dominance of adhesive stress. Finally, the shape of edge tip, where the surface and sides of the mushroom-shaped tip join, is a factor that impacts strength of adhesion. Optimizing ranges for these parameters are identified. |
| FILED | Tuesday, June 02, 2020 |
| APPL NO | 16/890204 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/00 (20130101) Original (OR) Class C09J 9/00 (20130101) C09J 2301/31 (20200801) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/20 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/10 (20130101) D10B 2401/06 (20130101) D10B 2403/0114 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2976 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11614544 | Taylor, Jr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Setter Research, Inc. (Greensboro, North Carolina) |
| ASSIGNEE(S) | Setter Research, Inc. (Greensboro, North Carolina) |
| INVENTOR(S) | David W. A. Taylor, Jr. (Greensboro, North Carolina) |
| ABSTRACT | Disclosed herein are methods, devices, and systems for determining geographic location and time. In one embodiment, a radio and a processor configured for deriving a first signal tone originating from a first remote antenna located at a first location; deriving a second signal tone originating from a second remote antenna located at a second location; deriving a third signal tone originating from a third remote antenna located at a third location; determining a first frequency and a first phase at a first time of the first signal tone; determining a second frequency and a second phase at a second time of the second signal tone; and determining a third frequency and a third phase at a third time of the third signal tone. The method further includes determining a geographic location based on the first, second, and third frequencies; the first, second, and third phases; and the first, second, and third locations. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/412325 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/25 (20130101) Original (OR) Class G01S 19/26 (20130101) G01S 19/243 (20130101) Wireless Communication Networks H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11613760 | Oikawa |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AFINGEN, INC. (Emeryville, California) |
| ASSIGNEE(S) | AFINGEN, INC. (Emeryville, California) |
| INVENTOR(S) | Ai Oikawa (Emeryville, California) |
| ABSTRACT | The present invention relates to transgenic plants with vascular xylem tissue-targeting overexpression of tissue factors involved in vascular xylem cell development. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/965809 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8223 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Education (ED)
| US 11612504 | Kuiken et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rehabilitation Institute of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | Rehabilitation Institute of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Todd Kuiken (Chicago, Illinois); Frank Ursetta (Chicago, Illinois) |
| ABSTRACT | The present disclosure is directed to a compact wrist rotator and flexor mechanism for use with a prosthetic hand. The wrist rotator and flexor uses a set of motors to provide a driven mechanism having two degrees of freedom, a wrist rotation and a wrist flexion. The rotator uses a motor with an inverted shaft gearbox combined with a worm gear and a face gear transmission to generate continuous and non-backdrivable rotation. The rotator is integrated into a flexor that uses a lead screw acting as a linear actuator to provide strong non-backdrivable flexion and extension. Due to the arrangement of the drives, the resulting wrist rotator and flexor mechanism has a low and compact profile. |
| FILED | Monday, December 14, 2020 |
| APPL NO | 17/121288 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/68 (20130101) A61F 2/80 (20130101) A61F 2/585 (20130101) Original (OR) Class A61F 2002/701 (20130101) A61F 2002/6836 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 17/0258 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 11613782 | Suliman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF CAPE TOWN (Cape Town, South Africa); STELLENBOSCH UNIVERSITY (Cape Town, South Africa); SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington); MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V (Munich, Germany); UNITED KINGDOM RESEARCH AND INNOVATION (Swindon, United Kingdom) |
| ASSIGNEE(S) | UNIVERSITY OF CAPE TOWN (Cape Town, South Africa); STELLENBOSCH UNIVERSITY (Cape Town, South Africa); SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington); MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V (Munich, Germany); UNITED KINGDOM RESEARCH AND INNOVATION (Swindon, United Kingdom) |
| INVENTOR(S) | Sara Suliman (Brookline, Massachusetts); Ethan Greene Thompson (Seattle, Washington); Jayne Suzanne Sutherland (Banjul, Gambia); Stefan H. E. Kaufmann (Berlin, Germany); Thomas Jens Scriba (Cape Town, South Africa); Daniel Edward Zak (Seattle, Washington); Gerhard Walzl (Cape Town, South Africa) |
| ABSTRACT | The invention provides a gene signature for use in determining a likelihood of a latent tuberculosis (TB) infection in a subject transitioning to active TB disease. The gene signature comprises at least SEPT4 and BLK, and optionally also GAS6 and/or CD1C. Expression levels of these genes are detected in a sample from the subject, and the ratios of expression of at least two of the above genes are calculated (e.g. SEPT4:BLK, SEPT4:CD1C, GAS6:BLK and/or GAS6:CD1C). A score is assigned to each ratio, the score being indicative of the likelihood of the latent TB infection transitioning into active TB disease, based on the ratio for the respective gene pair. The subject can be identified as having a latent TB infection that is likely to transition into active TB disease or that is not likely to transition into active TB disease based on the score or on the average of the scores. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/980121 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11613502 | Bartel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Christopher Bartel (Boulder, Colorado); Alan W. Weimer (Niwot, Colorado); Rebecca Jean O'Toole (Boulder, Colorado); Maila Kodas (Carlisle, Massachusetts) |
| ABSTRACT | Disclosed herein is a ceramic particle comprising a core substrate chosen from yttria-stabilized zirconia, partially stabilized zirconia, zirconium oxide, aluminum nitride, silicon nitride, silicon carbide, and cerium oxide, and a conformal coating of a sintering aid film having a thickness of less than three nanometers and covering the core substrate, and methods for producing the ceramic particle. |
| FILED | Saturday, November 04, 2017 |
| APPL NO | 16/347585 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/624 (20130101) C04B 35/4885 (20130101) Original (OR) Class C04B 35/62813 (20130101) C04B 2235/3217 (20130101) C04B 2235/3246 (20130101) C04B 2235/6026 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1253 (20130101) H01M 2008/1293 (20130101) H01M 2300/0077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11612874 | Ramler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Velocys, Inc. (Plain City, Ohio) |
| ASSIGNEE(S) | Velocys, Inc. (Plain City, Ohio) |
| INVENTOR(S) | Jeffrey J. Ramler (Lewis Center, Ohio); Anna Lee Tonkovich (Dublin, Ohio); Rachid D. Taha (Dublin, Ohio); Kai T. P. Jarosch (Bexley, Ohio); Robert J. Luzenski (Marysville, Ohio); Jeffery D. Slane (Galloway, Ohio); Thomas D. Hickey (Dublin, Ohio); Sean D. Fitzgerald (Columbus, Ohio); Harley D. Freeman (Dublin, Ohio); Frederick A. Zenz (Cold Spring, New York) |
| ABSTRACT | The invention providing methods of loading and unloading particulate from micorchannels in apparatus that contains multiple microchannels, typically apparatus that is designed to operate with hundreds or thousands of particulate-containing microchannels. Aligning a sonicating head at one end of a set of microchannels provides a particularly effective mode for densifying particulate in microchannels. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 16/418986 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) Original (OR) Class B01J 2219/0086 (20130101) B01J 2219/00788 (20130101) B01J 2219/00822 (20130101) B01J 2219/00824 (20130101) B01J 2219/00835 (20130101) B01J 2219/00867 (20130101) B01J 2219/00873 (20130101) B01J 2219/00891 (20130101) B01J 2219/00932 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11616187 | Graninger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aurelius L. Graninger (Sykesville, Maryland); Joel D. Strand (Ellicott City, Maryland); Micah John Atman Stoutimore (Kensington, Maryland); Zachary Kyle Keane (Baltimore, Maryland); Jeffrey David Hartman (Severn, Maryland); Justin C. Hackley (Catonsville, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Aurelius L. Graninger (Sykesville, Maryland); Joel D. Strand (Ellicott City, Maryland); Micah John Atman Stoutimore (Kensington, Maryland); Zachary Kyle Keane (Baltimore, Maryland); Jeffrey David Hartman (Severn, Maryland); Justin C. Hackley (Catonsville, Maryland) |
| ABSTRACT | Test structures and methods for superconducting bump bond electrical characterization are used to verify the superconductivity of bump bonds that electrically connect two superconducting integrated circuit chips fabricated using a flip-chip process, and can also ascertain the self-inductance of bump bond(s) between chips. The structures and methods leverage a behavioral property of superconducting DC SQUIDs to modulate a critical current upon injection of magnetic flux in the SQUID loop, which behavior is not present when the SQUID is not superconducting, by including bump bond(s) within the loop, which loop is split among chips. The sensitivity of the bump bond superconductivity verification is therefore effectively perfect, independent of any multi-milliohm noise floor that may exist in measurement equipment. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/168443 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2884 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/12 (20130101) H01L 24/16 (20130101) H01L 24/81 (20130101) H01L 25/0657 (20130101) H01L 27/18 (20130101) H01L 39/06 (20130101) H01L 39/08 (20130101) H01L 39/10 (20130101) H01L 39/12 (20130101) H01L 39/025 (20130101) Original (OR) Class H01L 39/223 (20130101) H01L 2224/13109 (20130101) H01L 2224/16145 (20130101) H01L 2224/81024 (20130101) H01L 2224/81908 (20130101) H01L 2225/06513 (20130101) H01L 2225/06596 (20130101) H01L 2924/1423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, March 28, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230328.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page