FedInvent™ Patents

Patent Details for Tuesday, May 02, 2023 

This page was updated on Tuesday, May 02, 2023 at 11:29 AM GMT

Department of Defense (DOD) 

US 11638645 Kumta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Prashant N. Kumta (Pittsburgh, Pennsylvania);  Gary Yu (Pittsburgh, Pennsylvania);  Abhijit Roy (Pittsburgh, Pennsylvania)
ABSTRACT The invention relates generally to generation of biomimetic scaffolds for bone tissue engineering and, more particularly, to multi-level lamellar structures having rotated or alternated plywood designs to mimic natural bone tissue. The invention also includes methods of preparing and applying the scaffolds to treat bone tissue defects. The biomimetic scaffold includes a lamellar structure having multiple lamellae and each lamella has a plurality of layers stacked parallel to one another. The lamellae and/or the plurality of layers is rotated at varying angles based on the design parameters from specific tissue structural imaging data of natural bone tissue, to achieve an overall trend in orientation to mimic the rotated lamellar plywood structure of the naturally occurring bone tissue.
FILED Tuesday, September 22, 2020
APPL NO 17/027810
ART UNIT 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/28 (20130101) Original (OR) Class
A61F 2/3094 (20130101)
A61F 2002/2835 (20130101)
A61F 2002/30062 (20130101)
A61F 2002/30224 (20130101)
A61F 2002/30973 (20130101)
A61F 2002/30985 (20130101)
A61F 2310/00005 (20130101)
A61F 2310/00017 (20130101)
A61F 2310/00023 (20130101)
A61F 2310/00029 (20130101)
A61F 2310/00041 (20130101)
A61F 2310/00293 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/165 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11638724 Badylak et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Stephen F. Badylak (West Lafayette, Indiana);  Anne E. Faust (Pittsburgh, Pennsylvania);  George S. Hussey (Cranberry Township, Pennsylvania);  Yolandi Van der Merwe (Pittsburgh, Pennsylvania);  Michael Brandt Steketee (Pittsburgh, Pennsylvania)
ABSTRACT Methods are disclosed herein for increasing retinal ganglion cell survival in a subject in need thereof. These methods include selecting a subject in need of increased retinal ganglion cell survival and administering a therapeutically effective amount of isolated nanovesicles derived from an extracellular matrix (MBVs) to the subject.
FILED Friday, May 04, 2018
APPL NO 16/610866
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0048 (20130101)
A61K 9/5176 (20130101)
A61K 35/22 (20130101) Original (OR) Class
A61K 38/44 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)
A61P 27/06 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1135 (20130101)
C12N 2310/141 (20130101)

Enzymes
C12Y 104/03013 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11638745 Jackson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth Cvctom of Hierher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Travis C. Jackson (Pittsburgh, Pennsylvania);  Patrick M. Kochanek (Pittsburgh, Pennsylvania)
ABSTRACT A method of improving brain function in a hypothermic patient is provided. The method comprises administering to the patient an amount of a fibroblast growth factor 21 (FGF21) effective to increase RNA binding motif 3 (RBM3) production in nerve cells of the patient. The method is useful, for example, where the patient is or will be undergoing cardiac surgery or spinal surgery, such as requiring deep hypothermia circulatory arrest (DHCA), or is subject to an emergency preservation and resuscitation (EPR) method, or where a patient suffers from mild/moderate/severe traumatic brain injury (TBI), ventricular fibrillation cardiac arrest (VFCA), subarachnoid hemorrhage (SAH), subdural hematoma (SH), cerebral vasospasm, neonatal abusive head trauma (a.k.a. shaken baby syndrome), neonatal hypoxic ischemic encephalopathy (HIE), asphyxia cardiac arrest (ACA), treatment of spinal injury, prophylaxis in spinal surgery, stroke, and drug overdose.
FILED Friday, May 20, 2016
APPL NO 15/573006
ART UNIT 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0226 (20130101)
A01N 1/0284 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 7/02 (20130101)
A61F 7/10 (20130101)
A61F 7/12 (20130101)
A61F 7/0097 (20130101)
A61F 2007/0002 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0043 (20130101)
A61K 9/0053 (20130101)
A61K 9/0085 (20130101)
A61K 38/1825 (20130101) Original (OR) Class
A61K 47/6811 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)
A61P 9/04 (20180101)
A61P 9/10 (20180101)
A61P 25/00 (20180101)
A61P 25/28 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11638748 Super et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Michael Super (Lexington, Massachusetts);  Edward J. Doherty (Mansfield, Massachusetts);  Mark Joseph Cartwright (West Newton, Massachusetts);  Des White (Oxford, Massachusetts);  Alexander Stafford (Revere, Massachusetts);  Omar Abdel-Rahman Ali (Oakland, California);  Amanda Graveline (Boston, Massachusetts);  Donald E. Ingber (Boston, Massachusetts);  David J. Mooney (Sudbury, Massachusetts);  Benjamin Seiler (Boston, Massachusetts)
ABSTRACT The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a pathogen in a subject having a pathogen infection, methods of increasing the surviving rate of a subject having a pathogen infection, methods of reducing the level of pain associated with a pathogen infection, and methods of reducing the level of distress associated with a pathogen infection in a subject in need thereof. Novel scaffold compositions and opsonin-bound or lectin-bound pathogen compositions, and uses thereof, are also provided herein.
FILED Wednesday, September 09, 2020
APPL NO 17/015177
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/025 (20130101)
A61K 39/0258 (20130101) Original (OR) Class
A61K 2039/58 (20130101)
A61K 2039/6031 (20130101)
A61K 2039/6093 (20130101)
A61K 2039/55522 (20130101)
A61K 2039/55561 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639014 Powell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brandon Powell (Washington, District of Columbia);  John A. Montgomery (Washington, District of Columbia)
ABSTRACT A method to improve thermal performance of vascular composites by using a two-phase working fluid for isothermalization includes the steps of: manufacturing a vascular composite structure optimized for a design point; manufacturing a thermal back end sized for the application; integrating the vascular composite into a fluid loop; and evacuating and filling the fluid loop with working fluid to an amount resulting in two-phase operation at the design point.
FILED Tuesday, December 10, 2019
APPL NO 16/709700
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 35/16 (20130101) Original (OR) Class
B29C 70/30 (20130101)
B29C 2035/1616 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/3076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639223 Allwein et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) General Atomics Aeronautical Systems, Inc. (San Diego, California)
ASSIGNEE(S) General Atomics Aeronautical Systems, Inc. (San Diego, California)
INVENTOR(S) Michael Joseph Allwein (San Luis Obispo, California);  Kevin David Koller (Ramona, California);  Ryan Bylard (San Diego, California);  Roy Hultenius (Encinitas, California)
ABSTRACT Features for in-flight recovery of an unmanned aerial vehicle (UAV). A towline may be deployed by a host aircraft in-flight to recover an in-flight target UAV. The towline or portion thereof may be oriented nearly vertical. The towline may have a fitting thereon. A capture mechanism on the target UAV may have one or more deployable flaps that engage with the near vertical towline and fitting. The flaps may stow to secure the target aircraft to the towline and fitting. The host aircraft may then retract the towline to pull in the target UAV to the host aircraft using a hoist system having a winch. A latching system located in a pylon of the host aircraft, which may be under a wing, may have a towline connector that engages with and secures the target UAV. The host aircraft may have multiple hoist systems for deployment and/or recovery of multiple target UAV's.
FILED Wednesday, November 17, 2021
APPL NO 17/455383
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 3/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639326 Collins et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) SRI INTERNATIONAL (Menlo Park, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Nathan Collins (San Mateo, California);  Jeremiah Malerich (San Jose, California);  Judy Szeto (Daly City, California);  Joseph A. Kozocas (Fremont, California)
ABSTRACT This disclosure generally relates to methods of making ibuprofen, naproxen, and derivatives thereof. This disclosure also generally relates to compounds made by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Friday, April 06, 2018
APPL NO 16/500687
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 17/16 (20130101)
C07C 17/16 (20130101)
C07C 22/04 (20130101)
C07C 29/143 (20130101)
C07C 29/143 (20130101)
C07C 33/22 (20130101)
C07C 45/46 (20130101)
C07C 45/46 (20130101)
C07C 49/76 (20130101)
C07C 51/08 (20130101) Original (OR) Class
C07C 51/08 (20130101)
C07C 57/30 (20130101)
C07C 57/30 (20130101)
C07C 253/14 (20130101)
C07C 253/14 (20130101)
C07C 253/16 (20130101)
C07C 255/01 (20130101)
C07C 255/33 (20130101)
C07C 303/28 (20130101)
C07C 303/28 (20130101)
C07C 309/66 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639412 Wynne et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James H. Wynne (Alexandria, Virginia);  Jeffrey G. Lundin (Springfield, Virginia);  Christopher L. Mcgann (Alexandria, Virginia);  Benjamin C. Streifel (Puyallup, Washington);  Michael G. Stockelman (Silver Spring, Maryland);  Chaselynn M. Watters (Silver Spring, Maryland);  Timothy B. Bentley (Rockville, Maryland);  Christopher J. Santee (Lansdowne, Virginia)
ABSTRACT A compound made by copolymerizing a poly(N-isopropylacrylamide) chain transfer agent, an acrylate salt, and a polyethylene glycol diacrylate. A compound made by copolymerizing a polyethylene glycol, a glycerol ethoxylate, and an aliphatic diisocyanate.
FILED Wednesday, September 11, 2019
APPL NO 16/567681
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/24 (20130101)
A61L 15/26 (20130101)
A61L 15/26 (20130101)
A61L 15/425 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/06 (20130101)
C08F 220/56 (20130101)
C08F 220/56 (20130101)
C08F 222/102 (20200201)
C08F 293/005 (20130101) Original (OR) Class

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/14 (20130101)
C08G 18/73 (20130101)
C08G 18/302 (20130101)
C08G 18/4812 (20130101)
C08G 18/4833 (20130101)
C08G 18/4841 (20130101)
C08G 18/6677 (20130101)
C08G 2110/0083 (20210101)
C08G 2210/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/00 (20130101)
C08J 9/28 (20130101)
C08J 2201/05 (20130101)
C08J 2201/028 (20130101)
C08J 2205/05 (20130101)
C08J 2205/022 (20130101)
C08J 2205/044 (20130101)
C08J 2207/10 (20130101)
C08J 2333/26 (20130101)
C08J 2353/00 (20130101)
C08J 2375/04 (20130101)

Compositions of Macromolecular Compounds
C08L 33/08 (20130101)
C08L 33/26 (20130101)
C08L 77/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639450 Webster et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
ASSIGNEE(S) NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
INVENTOR(S) Dean C. Webster (Fargo, North Dakota);  Mukund P. Sibi (Fargo, North Dakota);  Samantha D. Silbert (Fargo, North Dakota);  Eric M. Serum (Eau Claire, Wisconsin)
ABSTRACT The invention relates to curable non-isocyanate polyurethane coating compositions which is the reaction product of a polycarbamate resin and a dialdehyde. The invention also relates to methods of making and using the curable coating compositions of the invention. The invention also relates to objects coated with the curable coating composition of the invention.
FILED Tuesday, June 30, 2020
APPL NO 16/917009
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 71/04 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 175/06 (20130101)
C09D 175/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639456 Kamavaram et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Oceanit Laboratories, Inc. (Honolulu, Hawaii)
ASSIGNEE(S) Oceanit Laboratories, Inc. (Honolulu, Hawaii)
INVENTOR(S) Venkat Kamavaram (Honolulu, Hawaii);  Ravi Pare (Kailua, Hawaii)
ABSTRACT The present invention relates to thermally conductive materials, including, for instance, thermally conductive tubing and thermally conductive apparel, and applications thereof. In particular, the invention relates to thermally conductive tubing that can used in thermoregulatory apparel, such as, for example, cooling garments and cooling vests. In at least one embodiment, the present invention includes a thermally conductive material made from one or more base polymers and one or more additives that increase the thermal conductivity of the thermally conductive material relative to the one or more base polymers. The base polymer may include, for example, ethylene vinyl acetate (EVA), and the additive may include, for example, graphite fibers. The thermally conductive material may also include, for instance, a secondary polymer, such as ethylene propylene diene monomer (EPDM) and/or a plasticizer, such as bis(2-ethylhexyl) adipate (DEHA). Thermally conductive material produced according to one or more embodiments of the present invention may also be extruded or formed to create thermally conductive tubing and/or sheets.
FILED Monday, January 11, 2021
APPL NO 17/146442
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 110/02 (20130101)
C08F 118/08 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/203 (20130101)
C08J 5/18 (20130101)
C08J 2323/08 (20130101)
C08J 2331/04 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/04 (20130101)
C08K 3/22 (20130101)
C08K 3/38 (20130101)
C08K 3/041 (20170501)
C08K 3/042 (20170501)
C08K 5/11 (20130101)
C08K 7/06 (20130101)
C08K 13/04 (20130101)
C08K 2003/385 (20130101)
C08K 2003/2296 (20130101)
C08K 2201/001 (20130101)
C08K 2201/011 (20130101)
C08K 2201/014 (20130101)

Compositions of Macromolecular Compounds
C08L 23/0853 (20130101)
C08L 31/04 (20130101)
C08L 2203/16 (20130101)
C08L 2205/06 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 5/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639514 Dresios et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) Leidos, Inc. (Reston, Virginia)
ASSIGNEE(S) Leidos, Inc. (Reston, Virginia)
INVENTOR(S) John Dresios (Carlsbad, California);  Richard Holmes Griffey (Vista, California);  Challise J. Sullivan (San Diego, California);  Erik D. Pendleton (San Diego, California);  Henri M. Sasmor (Oceanside, California);  William L. Hicks (San Diego, California);  Eric M. Amendt (San Diego, California)
ABSTRACT A portable fluidic platform for rapid and flexible end-to-end production of recombinant protein biologics includes a bioreactor system hosting stable and robust cell-free translation systems that is fluidically integrated with modular protein separation functionalities (e.g., size exclusion, ion exchange or affinity chromatography systems) for purification of the cell-free expressed product and which are configurable for process-specific isolation of different proteins, as well as for formulation. The bioreactor utilizes lysates from engineered eukaryotic (e.g., yeast) or prokaryotic (e.g., bacterial) strains that contain factors for protein folding and posttranslational modifications. Combination of various purification modules on the same fluidic platform allows flexibility of re-routing for purification of different proteins depending on specific target requirements. Protein synthesis and purification modules are integrated into self-contained disposable fluidic cartridge that eliminates cross-contamination between runs. The platform allows for flexible production of protein biologics within 24 hours (from DNA to purified product).
FILED Friday, April 10, 2020
APPL NO 16/846025
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Separation
B01D 15/10 (20130101)
B01D 15/12 (20130101)
B01D 15/14 (20130101)
B01D 15/22 (20130101)
B01D 15/34 (20130101)
B01D 15/361 (20130101)
B01D 15/3804 (20130101)

Peptides
C07K 14/505 (20130101)
C07K 14/535 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 21/18 (20130101)
C12M 23/28 (20130101)
C12M 23/44 (20130101)
C12M 29/00 (20130101)
C12M 41/48 (20130101)
C12M 47/10 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/06 (20130101)
C12N 9/1223 (20130101)
C12N 9/1252 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/00 (20130101) Original (OR) Class
C12P 21/02 (20130101)
C12P 21/06 (20130101)

Enzymes
C12Y 207/03002 (20130101)
C12Y 207/07007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639915 Giurgiutiu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) University of South Carolina (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Victor Giurgiutiu (Columbia, South Carolina);  Jingjing Bao (West Columbia, South Carolina);  Banibrata Poddar (Germantown, Maryland);  Md Yeasin Bhuiyan (West Columbia, South Carolina)
ABSTRACT The current disclosure determines if structural faults exist and extracts geometric features of the structural faults from acoustic emission waveforms, such as crack length and orientation, and can evaluate the structural faults online, during normal operation conditions.
FILED Friday, September 11, 2020
APPL NO 17/018327
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/14 (20130101) Original (OR) Class
G01N 29/46 (20130101)
G01N 29/2437 (20130101)
G01N 29/4454 (20130101)
G01N 2291/0231 (20130101)
G01N 2291/0232 (20130101)
G01N 2291/0258 (20130101)
G01N 2291/0289 (20130101)
G01N 2291/2634 (20130101)
G01N 2291/2693 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639932 Roy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
APPLICANT(S) Orono Spectral Solutions, Inc. (Bangor, Maine)
ASSIGNEE(S) Orono Spectral Solutions, Inc. (Hermon, Maine)
INVENTOR(S) Eric Roy (Lisbon Falls, Maine);  Rachel Gettings (Bangor, Maine);  Luke Doucette (Hampden, Maine)
ABSTRACT An apparatus for capturing a target analyte in advance of performing spectroscopic analysis to determine the existence of the target analyte from a source contacted with a collection substrate. The collection substrate is fabricated of a material selected to have an affinity for the target analyte, sufficiently transparent in a spectral region of interest and capable of immobilizing the target analyte thereon in a manner that limits scattering sufficient to obscure spectral analysis. The collection substrate may be coated with a material selected to react with, bind to, or absorb the target analyte. The target analyte may be captured to the collection substrate by one or more of wiping, dabbing or swabbing a target analyte carrier with the collection substrate.
FILED Monday, March 22, 2021
APPL NO 17/208891
ART UNIT 1796 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5029 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/02 (20130101)
G01N 1/04 (20130101)
G01N 21/552 (20130101)
G01N 21/3563 (20130101)
G01N 33/54373 (20130101) Original (OR) Class
G01N 2001/028 (20130101)
G01N 2001/045 (20130101)
G01N 2021/3595 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639973 Montoya et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) Naval Information Warfare Center Pacific (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Sergio A Montoya (Chula Vista, California);  Benjamin J Taylor (Escondido, California);  Susan Anne Elizabeth Berggren (San Diego, California);  Anna Leese de Escobar (Encinitas, California);  Nicholas Ferrante (Lakeside, California)
ABSTRACT A superconducting electronic circuit includes at least two SQUID elements, an array of at least three Josephson Junctions, and a magnetic source element. Each SQUID element has no shared Josephson Junctions or at least one shared Josephson Junction with another SQUID element and at least one exclusive Josephson Junction. The array of at least three Josephson Junctions are connected in one, two, or three-dimensions. The magnetic source element has an electrically-tunable spatially non-uniform magnetic field.
FILED Wednesday, July 14, 2021
APPL NO 17/375118
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/0354 (20130101) Original (OR) Class

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 6/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639994 Paulus
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
INVENTOR(S) Mark Paulus (Poulsbo, Washington)
ABSTRACT An acoustic vector sensor has an array of sensors to detect at least the bearing of a target. The acoustic vector sensor or hydrophone with sensor array avoids the need to deploy multiple hydrophones each with a single sensor. The array of sensor signals can be processed using any one of a number of methods.
FILED Friday, July 17, 2020
APPL NO 16/873829
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 5/18 (20130101)
G01S 15/588 (20130101) Original (OR) Class

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/186 (20130101)
G01V 2210/1427 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11640043 Lentz
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) US Gov't as represented by Secy of Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Joshua Lentz (Niceville, Florida)
ABSTRACT An optical focus control and method use rotations of a set of shift-invariant optical elements (Risley elements) that are fairly tolerant to optical misalignments and wobble in control systems. The Risley elements can be Risley prisms, Risley gratings, or photonic crystals that impart a fixed angular offset. Aligning at least one pair of Risley elements that are individually rotated can achieve an angular correct to light received off-axis for better detection by an optical detector, improving focus control.
FILED Monday, January 03, 2022
APPL NO 17/567452
ART UNIT 2871 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/04 (20130101)
G02B 7/28 (20130101) Original (OR) Class

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/139 (20130101)
G02F 1/133528 (20130101)
G02F 1/133607 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11640079 Sitter, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S) David N. Sitter, Jr. (El Segundo, California)
ABSTRACT A beam splitter configured to split incident light includes a polarization grating having a liquid crystal layer and a reflective sub-aperture beam splitter. The liquid crystal layer is configured to switch between an “on” state and an “off” state in response to an applied voltage. In the “off” state, the polarization grating angularly deviates and polarizes a portion of received incident light passing therethrough. In the “on” state, crystals of the polarization grating align with the incident light, allowing it to pass therethrough unimpeded and unpolarized. The beam splitter includes a plurality of sub-aperture mirrors which are spaced at randomly varying distances from one another, the mirrors being configured to reflect a portion of the incident light.
FILED Thursday, July 23, 2020
APPL NO 16/937224
ART UNIT 2871 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/283 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/133528 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11640893 Borchard et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Dymenso LLC (San Francisco, California)
ASSIGNEE(S) Dymenso LLC (San Francisco, California)
INVENTOR(S) Philipp Borchard (San Francisco, California);  Joseph S. Hoh (Richmond, California)
ABSTRACT A high-power vacuum electron device source of 10 mm-0.1 mm wavelength radiation is composed of an electron gun joined to a RF vacuum electronic circuit. The electron gun includes a cathode, a focus electrode, and a grid. It generates an electron beam that is injected into the circuit for amplifying RF waves. The circuit is composed of metal circuit plates, e.g., copper alloy, that mate with each other and are shaped to provide a beam tunnel and RF circuit envelopes. Precision alignment pins made of nickel super alloy, are used to mutually align the metal circuit plates using elastic averaging implemented by positioning the precision alignment pins in precision alignment holes in the metal circuit plates. Preferably, the electron gun is aligned with the circuit using quasi-kinematic coupling.
FILED Thursday, November 18, 2021
APPL NO 17/530042
ART UNIT 2875 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 29/04 (20130101)
H01J 29/54 (20130101)
H01J 29/66 (20130101) Original (OR) Class
H01J 2223/083 (20130101)
H01J 2229/481 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11641003 Razeghi
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Manijeh Razeghi (Wilmette, Illinois)
ABSTRACT Diffusion-based and ion implantation-based methods are provided for fabricating planar photodetectors. The methods may be used to fabricate planar photodetectors comprising type II superlattice absorber layers but without mesa structures. The fabricated planar photodetectors exhibit high quantum efficiencies, low dark current densities, and high specific detectivities as compared to photodetectors having mesa structures.
FILED Monday, November 30, 2020
APPL NO 17/106937
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/101 (20130101)
H01L 31/105 (20130101)
H01L 31/1035 (20130101)
H01L 31/1844 (20130101) Original (OR) Class
H01L 31/03046 (20130101)
H01L 31/035236 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11641194 Whiteley
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) Synopsys, Inc. (Mountain View, California)
ASSIGNEE(S) Synopsys, Inc. (Mountain View, California)
INVENTOR(S) Stephen Robert Whiteley (Sunnyvale, California)
ABSTRACT A circuit can include a first sub-circuit, a second sub-circuit, and a third sub-circuit. The first sub-circuit can store a reset state or a set state, and can include a first Josephson junction (JJ), a second JJ, and a third JJ coupled in parallel using superconducting inductors. The first JJ, the second JJ, and the third JJ can be biased using a JJ-based current source. The second sub-circuit can switch the first sub-circuit to the set state in response to receiving a pulse. The third sub-circuit can switch the first sub-circuit to the reset state in response to receiving one or more pulses.
FILED Friday, July 10, 2020
APPL NO 16/926385
ART UNIT 2849 — Printing/Measuring and Testing
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/22 (20130101)
H01L 39/223 (20130101)

Pulse Technique
H03K 3/38 (20130101) Original (OR) Class
H03K 19/1954 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11641411 Agassounon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Textron Systems Corporation (Hunt Valley, Maryland)
ASSIGNEE(S) Textron Systems Corporation (Hunt Valley, Maryland)
INVENTOR(S) William Agassounon (North Reading, Massachusetts);  Robert Newcomb Litchfield (Litchfield, New Hampshire);  Andrew Kevin McCann (Graveland, Massachusetts)
ABSTRACT A technique of managing communications among multiple modules of a munition includes receiving, by a first module of the munition, a first set of messages from a second module of the munition. The first set of messages is received in a first protocol used for communicating among the modules of the munition over a computer network. The technique further includes translating, by an interface assembly of the first module, the first set of messages in the first protocol into a second set of messages in a second protocol. The second protocol is a native protocol of the first module and is different from the first protocol. The technique still further includes providing the second set of messages from the interface module to an operational component of the first module, the operational component then responding to the second set of messages for performing a function of the munition.
FILED Friday, August 28, 2020
APPL NO 17/006104
ART UNIT 2469 — Multiplex and VoIP
CURRENT CPC
Weapon Sights; Aiming
F41G 7/007 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 12/5601 (20130101)
H04L 12/5691 (20130101)
H04L 67/12 (20130101)
H04L 69/18 (20130101) Original (OR) Class
H04L 2012/563 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11641531 Moebius et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Charles Stark Draper Laboratory Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Michael Moebius (Allston, Massachusetts);  Julian Brown (Cambridge, Massachusetts);  Steven Spector (Lexington, Massachusetts);  Benjamin Lane (Sherborn, Massachusetts);  Alan Zhou (Brookline, Massachusetts);  Hannah Anne Clevenson (Cambridge, Massachusetts);  Lucas David Benney (Brighton, Massachusetts)
ABSTRACT A compressive/transform imager comprising a lens array positioned above input ports for collecting light into the input ports, waveguides routing the light from the input port to waveguide mixing regions (e.g. multi-mode interference couplers), and detectors for receiving outputs of the waveguide mixing regions.
FILED Monday, December 07, 2020
APPL NO 17/113956
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 3/0043 (20130101)
G02B 3/0056 (20130101)
G02B 6/2813 (20130101)
G02B 6/4215 (20130101)
G02B 6/29344 (20130101)
G02B 27/0087 (20130101)
G02B 2005/1804 (20130101)

Pictorial Communication, e.g Television
H04N 5/369 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11641699 Pirlo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Naw (Washington, District of Columbia)
INVENTOR(S) Russell Kirk Pirlo (Oakwood, Ohio);  Joel D. Gaston (Alexandria, Virginia)
ABSTRACT A device having: an article having a flat surface and a lower surface opposed to the flat surface; a cavity formed in the lower surface forming a complete loop surrounding a central portion of the article; a heating element having the same shape as the complete loop in the cavity and positioned to warm a portion of the flat surface adjacent to the heating element when the heating element is activated; a cooling device positioned to cool a portion of the flat surface in the central portion; and a release layer on the flat surface. A device having: an article having an upper surface; a heating element on the upper surface forming a complete loop surrounding a central portion of the article; and an electrically insulating material on the upper surface within the central portion.
FILED Wednesday, September 29, 2021
APPL NO 17/488738
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/0015 (20130101)
D01D 5/0061 (20130101)
D01D 5/0076 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 3/40 (20130101) Original (OR) Class
H05B 3/64 (20130101)
H05B 2213/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 11638522 Abramoff et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Michael D. Abramoff (University Heights, Iowa);  Meindert Niemeijer (Iowa City, Iowa);  Xiayu Xu (Iowa City, Iowa);  Milan Sonka (Coralville, Iowa);  Joseph M. Reinhardt (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa);  United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Michael D. Abramoff (University Heights, Iowa);  Meindert Niemeijer (Iowa City, Iowa);  Xiayu Xu (Iowa City, Iowa);  Milan Sonka (Coralville, Iowa);  Joseph M. Reinhardt (Iowa City, Iowa)
ABSTRACT The methods and systems provided can automatically determine an Arteriolar-to-Venular diameter Ratio, AVR, in blood vessels, such as retinal blood vessels and other blood vessels in vertebrates. The AVR is an important predictor of increases in the risk for stroke, cerebral atrophy, cognitive decline, and myocardial infarct.
FILED Monday, March 26, 2018
APPL NO 15/936162
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/12 (20130101) Original (OR) Class
A61B 3/0016 (20130101)
A61B 3/0058 (20130101)
A61B 3/1225 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11638645 Kumta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Prashant N. Kumta (Pittsburgh, Pennsylvania);  Gary Yu (Pittsburgh, Pennsylvania);  Abhijit Roy (Pittsburgh, Pennsylvania)
ABSTRACT The invention relates generally to generation of biomimetic scaffolds for bone tissue engineering and, more particularly, to multi-level lamellar structures having rotated or alternated plywood designs to mimic natural bone tissue. The invention also includes methods of preparing and applying the scaffolds to treat bone tissue defects. The biomimetic scaffold includes a lamellar structure having multiple lamellae and each lamella has a plurality of layers stacked parallel to one another. The lamellae and/or the plurality of layers is rotated at varying angles based on the design parameters from specific tissue structural imaging data of natural bone tissue, to achieve an overall trend in orientation to mimic the rotated lamellar plywood structure of the naturally occurring bone tissue.
FILED Tuesday, September 22, 2020
APPL NO 17/027810
ART UNIT 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/28 (20130101) Original (OR) Class
A61F 2/3094 (20130101)
A61F 2002/2835 (20130101)
A61F 2002/30062 (20130101)
A61F 2002/30224 (20130101)
A61F 2002/30973 (20130101)
A61F 2002/30985 (20130101)
A61F 2310/00005 (20130101)
A61F 2310/00017 (20130101)
A61F 2310/00023 (20130101)
A61F 2310/00029 (20130101)
A61F 2310/00041 (20130101)
A61F 2310/00293 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/165 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11638728 Gajewski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Thomas F. Gajewski (Chicago, Illinois);  Jason Luke (Oak Park, Illinois);  Riyue Bao (Chicago, Illinois);  Vyara Matson (Chicago, Illinois);  Jessica Fessler (Chicago, Illinois)
ABSTRACT Provided herein are compositions and methods comprising microbiome biomarkers of responsiveness/resistance to immunotherapy (e.g., anti-PD1/PD-L1 therapy), and diagnostic, prognostic and therapeutic uses thereof. In particular, the amount, identity, presence, and/or ratio of microflora in the microbiome of a subject is used to determine the responsiveness/resistance of the subject to immunotherapy, and/or the microbiome of a subject is manipulated to enhance the responsiveness of the subject to various immunotherapies and co-therapies.
FILED Tuesday, June 05, 2018
APPL NO 16/618700
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/745 (20130101) Original (OR) Class
A61K 35/747 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2818 (20130101)
C07K 16/2827 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11638745 Jackson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth Cvctom of Hierher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Travis C. Jackson (Pittsburgh, Pennsylvania);  Patrick M. Kochanek (Pittsburgh, Pennsylvania)
ABSTRACT A method of improving brain function in a hypothermic patient is provided. The method comprises administering to the patient an amount of a fibroblast growth factor 21 (FGF21) effective to increase RNA binding motif 3 (RBM3) production in nerve cells of the patient. The method is useful, for example, where the patient is or will be undergoing cardiac surgery or spinal surgery, such as requiring deep hypothermia circulatory arrest (DHCA), or is subject to an emergency preservation and resuscitation (EPR) method, or where a patient suffers from mild/moderate/severe traumatic brain injury (TBI), ventricular fibrillation cardiac arrest (VFCA), subarachnoid hemorrhage (SAH), subdural hematoma (SH), cerebral vasospasm, neonatal abusive head trauma (a.k.a. shaken baby syndrome), neonatal hypoxic ischemic encephalopathy (HIE), asphyxia cardiac arrest (ACA), treatment of spinal injury, prophylaxis in spinal surgery, stroke, and drug overdose.
FILED Friday, May 20, 2016
APPL NO 15/573006
ART UNIT 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0226 (20130101)
A01N 1/0284 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 7/02 (20130101)
A61F 7/10 (20130101)
A61F 7/12 (20130101)
A61F 7/0097 (20130101)
A61F 2007/0002 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0043 (20130101)
A61K 9/0053 (20130101)
A61K 9/0085 (20130101)
A61K 38/1825 (20130101) Original (OR) Class
A61K 47/6811 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)
A61P 9/04 (20180101)
A61P 9/10 (20180101)
A61P 25/00 (20180101)
A61P 25/28 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11638763 Bilgicer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Notre Dame du Lac (South Bend, Indiana)
ASSIGNEE(S) University of Notre Dame du Lac (South Bend, Indiana)
INVENTOR(S) Zihni Basar Bilgicer (South Bend, Indiana);  Peter Edward Deak (South Bend, Indiana);  Tanyel Kiziltepe Bilgicer (South Bend, Indiana);  Jared Francis Stefanick (South Bend, Indiana);  Jonathan Darryl Ashley (South Bend, Indiana)
ABSTRACT Embodiments of the present disclosure provide a nanoparticle based platform, and nanoallergens for identifying, evaluating and studying allergen mimotopes as multiple copies of a single mimotope or various combinations on the same particle. The nanoparticle is extremely versatile and allows multivalent binding to IgEs specific to a variety of mimotopes, simulating allergen proteins. Nanoparticles can include various molecular ratios of components. For example, the nanoallergens can include about 0.1-40% mimotope-lipid conjugate and about 60-99.9% lipid. The mimotope-lipid conjugate includes a mimotope, a first linker, and lipid molecule. Nanoallergens can be used in in vitro and in vivo applications to identify a specific patient's sensitivity to a set of epitopes and predict a symptomatic clinical response, identify allergen epitopes through blind screening peptide sequences from allergen protein, and in a clinical application similar to a scratch test.
FILED Friday, December 18, 2020
APPL NO 17/126616
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/1271 (20130101)
A61K 39/35 (20130101)
A61K 47/6911 (20170801)
A61K 49/0006 (20130101) Original (OR) Class
A61K 2039/60 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/40 (20130101)

Enzymes
C12Y 302/01052 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/586 (20130101)
G01N 33/686 (20130101)
G01N 33/6854 (20130101)
G01N 2800/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11638778 Wu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland);  BREETHE, INC (Halethorpe, Maryland)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland);  Breethe, Inc. (Halethorpe, Maryland)
INVENTOR(S) Zhongjun Wu (Marriottsville, Maryland);  Bartley Griffith (Gibson Island, Maryland);  David N. Wells (Silver Spring, Maryland)
ABSTRACT An oxygen supply unit for use with a blood oxygenator comprises an oxygen concentrator and a carbon dioxide scrubber. In an on-line operational mode, oxygen-rich gas from the oxygen concentrator is predominantly supplied to the blood oxygenator with a reduced flow of recycled gas from the concentrator. In an off-line operational mode where the oxygen supply unit is being powered by battery only, a larger flow of recycled gas from the blood oxygenator is passed through the carbon dioxide scrubber and combined with a lesser amount of oxygen-rich gas from the oxygen concentrator. The oxygen supply unit may be used in combination with a blood pump and oxygenator to provide ambulatory blood oxygenation to patients with compromised lung function.
FILED Wednesday, August 14, 2019
APPL NO 16/540102
ART UNIT 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/1698 (20130101)
A61M 1/3666 (20130101)
A61M 1/3667 (20140204) Original (OR) Class
A61M 2202/0208 (20130101)
A61M 2205/8206 (20130101)
A61M 2209/08 (20130101)
A61M 2209/088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639335 Amaravadi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Ravi K. Amaravadi (Media, Pennsylvania);  Jeffrey D. Winkler (Wynnewood, Pennsylvania)
ABSTRACT The invention provides novel asymmetric and symmetric bisaminoquinolmes and related compounds, methods of treatment and syntheses. The novel compounds exhibit effective anticancer activity and are useful in the treatment of a variety of autophagy-related disorders.
FILED Tuesday, April 13, 2021
APPL NO 17/229012
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/436 (20130101)
A61K 31/506 (20130101)
A61K 31/517 (20130101)
A61K 31/519 (20130101)
A61K 31/704 (20130101)
A61K 31/4375 (20130101)
A61K 31/4545 (20130101)
A61K 31/4706 (20130101)
A61K 31/4706 (20130101)
A61K 31/4709 (20130101)
A61K 31/4709 (20130101)
A61K 31/4745 (20130101)
A61K 31/4995 (20130101)
A61K 31/7056 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 215/46 (20130101) Original (OR) Class
C07D 401/12 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639340 Scheidt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Karl A. Scheidt (Evanston, Illinois);  Rick C. Betori (Gurnee, Illinois);  Benjamin R. McDonald (Somerville, Massachusetts)
ABSTRACT Disclosed are chromane compounds, analogs thereof, and methods of their synthesis and use. The compounds may be synthesized by methods involving reductive annulations of arylidene malonates with unsaturated electrophiles using photoredox/Lewis acid cooperative catalysis. The compounds may be formulated in a pharmaceutical composition for treating one of the aforementioned diseases or disorders.
FILED Wednesday, July 08, 2020
APPL NO 16/923843
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 215/14 (20130101)
C07D 215/58 (20130101)
C07D 307/80 (20130101)
C07D 311/58 (20130101) Original (OR) Class
C07D 311/92 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639359 Castor
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Trevor Percival Castor (Arlington, Massachusetts)
ASSIGNEE(S) APHIOS CORPORATION (Woburn, Massachusetts)
INVENTOR(S) Trevor Percival Castor (Arlington, Massachusetts)
ABSTRACT Embodiments of the present invention feature novel Bryoid compositions, methods of making and methods of treating disease.
FILED Sunday, March 21, 2021
APPL NO 17/207675
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/365 (20130101)

Heterocyclic Compounds
C07D 493/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639379 Bubeck-Wardenburg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Juliane Bubeck-Wardenburg (Frankfort, Illinois);  Olaf Schneewind (Chicago, Illinois)
ABSTRACT Embodiments of the invention include methods and compositions useful in a vaccination strategy capable of neutralizing Hla to provide immunoprotection against S. aureus pneumonia. In certain aspects the invention includes a Hla with reduced toxicity, represented by a recombinant mutant form of Hla (HlaH35L) in which histidine 35 is converted to leucine, which can be used to abrogate the productive assembly of the toxin and protect a subject from staphylococcal pneumonia.
FILED Tuesday, May 19, 2020
APPL NO 15/929741
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/40 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/1271 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639508 Kass et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) David A. Kass (Baltimore, Maryland);  Mark J. Ranek (Baltimore, Maryland);  Kristen Kokkonen (Baltimore, Maryland);  Jonathan D. Powell (Baltimore, Maryland);  Chirag Patel (Baltimore, Maryland)
ABSTRACT Provided herein are engineered TSC2 polypeptides, and nucleic acid sequences encoding them, in which the ability of a serine residue to be phosphorylated is altered. In some aspects, the TSC2 serine residue cannot be phosphorylated (e.g., by substituting the serine residue with an alanine residue). In some aspects, the TSC2 serine acts as if it is constitutively phosphorylated (e.g., by substituting the serine residue with a glutamic acid residue). Also provided herein are engineered immune cells comprising altered TSC2 polypeptides or nucleic acid sequences encoding them, and methods of making and using such engineered immune cells.
FILED Friday, July 13, 2018
APPL NO 16/631069
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639509 Samulski
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
NIH Office of the Director (NIHOD)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Richard Jude Samulski (Hillsborough, North Carolina)
ABSTRACT Disclosed herein are methods and compositions comprising an adeno-associated virus 2.5 (AAV2.5) capsid protein, comprising one or more amino acids substitutions, (e.g., which does not contain a substitution at the position corresponding to amino acid 267 of AAV2.5, or does not contain a serine at the position corresponding to amino acid 267 of AAV2.5) wherein the substitutions introduce a new glycan binding site into the AAV capsid protein.
FILED Friday, January 21, 2022
APPL NO 17/581639
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/16 (20180101)
A61P 31/18 (20180101)
A61P 31/20 (20180101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2750/14122 (20130101)
C12N 2750/14142 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14171 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639518 Church et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) George M. Church (Brookline, Massachusetts);  Jehyuk Lee (Allston, Massachusetts);  Daniel Levner (Boston, Massachusetts);  Michael Super (Lexington, Massachusetts)
ABSTRACT Methods of analyzing nucleic acids of a cell are provided.
FILED Wednesday, January 26, 2022
APPL NO 17/584959
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6804 (20130101)
C12Q 1/6806 (20130101) Original (OR) Class
C12Q 1/6816 (20130101)
C12Q 1/6837 (20130101)
C12Q 1/6844 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6874 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 2458/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639519 Seelig et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Georg Seelig (Seattle, Washington);  Richard Muscat (London, United Kingdom);  Alexander B. Rosenberg (Seattle, Washington)
ABSTRACT Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
FILED Monday, July 25, 2022
APPL NO 17/814712
ART UNIT 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101) Original (OR) Class
C12Q 1/6855 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639523 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Feng Zhang (Cambridge, Massachusetts);  Jonathan Gootenberg (Cambridge, Massachusetts);  Omar Abudayyeh (Cambridge, Massachusetts);  Julia Joung (Cambridge, Massachusetts);  Alim Ladha (Cambridge, Massachusetts);  Han Altae-Tran (Cambridge, Massachusetts);  Guilhem Faure (Cambridge, Massachusetts)
ABSTRACT Engineered or non-naturally occurring systems and compositions comprising a novel Cas12b and a guide molecule. Also provided include methods of use the systems and compositions, including in treating and diagnosing diseases.
FILED Friday, June 05, 2020
APPL NO 16/894678
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 7/52 (20130101)
B01L 2300/0816 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/78 (20130101)
C12N 9/1276 (20130101)
C12N 2310/20 (20170501)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6844 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
C12Q 2600/156 (20130101)

Enzymes
C12Y 207/07049 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2333/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639930 Kumar et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The U.S.A., as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland);  Yale University (New Haven, Connecticut)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland);  Yale University (New Haven, Connecticut)
INVENTOR(S) Sanjai Kumar (Potomac, Maryland);  Nitin Verma (Germantown, Maryland);  Ankit Puri (Rockville, Maryland);  Peter J. Krause (Old Saybrook, Connecticut)
ABSTRACT Identification of immunodominant Babesia microti antigens using genome-wide immunoscreening is described. Candidate antigens were screened against sera from patients with clinical babesiosis. Also described are diagnostic assays with high sensitivity and specificity for detecting B. microti-specific antibodies in patient samples using the identified immunodominant antigens.
FILED Thursday, November 01, 2018
APPL NO 16/761034
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/44 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1096 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54306 (20130101) Original (OR) Class
G01N 33/56905 (20130101)
G01N 2469/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639941 Warner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) ICAGEN, LLC (San Diego, California)
ASSIGNEE(S) Icagen, LLC (Emeryville, California)
INVENTOR(S) Benjamin P. Warner (Los Alamos, New Mexico);  Lori J. Peterson (Los Alamos, New Mexico);  Jennifer A. Berger (Los Alamos, New Mexico);  Eva R. Birnbaum (Los Alamos, New Mexico);  Rebecca L. E. Miller (Los Alamos, New Mexico)
ABSTRACT The present invention includes a method and apparatus for measuring the transport of analytes from living, biological cells through a cell barrier, which includes, but is not limited to, steps of providing the living, biological cells loaded with analytes, unloading at least a portion of said analytes from the cells through ion channels, removing unloaded analyte remaining in the cells, and measuring the analytes using x-ray fluorescence, specifically wherein the measurement uses an energy dispersive x-ray fluorescence spectrometer equipped with a microfocus x-ray tube. These steps may be repeated so that multiple measurements can be obtained over a period of time.
FILED Wednesday, August 22, 2018
APPL NO 16/109049
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/223 (20130101)
G01N 33/502 (20130101)
G01N 33/6872 (20130101) Original (OR) Class
G01N 2223/076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11640204 Shenoy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Krishna V. Shenoy (Stanford, California);  Jaimie M. Henderson (Stanford, California);  Francis Robert Willett (Palo ALto, California)
ABSTRACT Systems and methods for decoding intended symbols from neural activity in accordance with embodiments of the invention are illustrated. One embodiment includes a symbol decoding system for brain-computer interfacing, including a neural signal recorder implanted into a brain of a user, and a symbol decoder, the symbol decoder including a processor, and a memory, where the memory includes a symbol decoding application capable of directing the processor to obtain neural signal data from the neural signal recorder, estimate a symbol from the neural signal data using a symbol model, and perform a command associated with the symbol.
FILED Friday, August 28, 2020
APPL NO 17/006645
ART UNIT 2622 — Selective Visual Display Systems
CURRENT CPC
Electric Digital Data Processing
G06F 3/015 (20130101) Original (OR) Class

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 9/00496 (20130101)
G06K 9/6254 (20130101)
G06K 9/6257 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 7/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11641168 Degertekin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Fahrettin Levent Degertekin (Atlanta, Georgia);  Sarp Satir (Atlanta, Georgia);  Sushruta Surappa (Atlanta, Georgia)
ABSTRACT A parametric resonator can be driven by varying a parameter of a modulated capacitor or other externally powered type device to achieve transduction. Conventionally, externally powered type devices generally require an external power source or a static charge to achieve transduction. By pumping the parameter of the device at a frequency that is about twice the resonance frequency, and an amplitude that is above a threshold, however parametric resonance can be generated and sustained without requiring an external power source or charge to be applied to the device.
FILED Tuesday, July 17, 2018
APPL NO 16/038137
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/3787 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/2406 (20130101)
G01N 2291/02827 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/15 (20160201)

Electric Machines Not Otherwise Provided for
H02N 2/188 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE49514 Chopra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Board of Regents of The University of Texas System (Austin, Texas);  Westport Bio, LLC (Sugar Land, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas);  Westport Bio, LLC (Sugar Land, Texas)
INVENTOR(S) Ashok K. Chopra (League City, Texas);  Vladimir L. Motin (League City, Texas);  Eric Rothe (Houston, Texas)
ABSTRACT Provided herein are methods for using compositions that include a fusion protein having a YscF protein domain, a mature F1 protein domain, and a LcrV protein domain. In one embodiment the composition is used to confer immunity to plague, such as pneumonic plague, caused by Yersinia pestis. In one embodiment, the composition is administered to a mucosal surface, such as by an intranasal route. In one embodiment, the administration to a mucosal surface includes a vector that has a polynucleotide encoding a fusion protein, where the fusion protein includes a YscF protein domain, a mature F1 protein domain, and a LcrV protein domain. The administration is followed by a second administration by a different route, such as an intramuscular route. The second administration includes a fusion protein having the same three domains, and in one embodiment the fusion protein is the same one administered to a mucosal surface.
FILED Thursday, September 17, 2020
APPL NO 17/023547
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/025 (20130101)
A61K 39/0291 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/70 (20130101)
A61K 2039/543 (20130101)
A61K 2039/545 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/10043 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11638907 Campbell et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Patrick Campbell (Oakland, California);  Sarah Baker (Dublin, California);  Maira Ceron Hernandez (Livermore, California);  Jennifer Marie Knipe (Oakland, California);  Joshuah K. Stolaroff (Oakland, California)
ABSTRACT In accordance with one aspect of the presently disclosed inventive concepts, a porous ceramic structure includes a three-dimensional printed structure having predefined features, where the three-dimensional structure has a geometric shape. The average length of the features may be at least 10 microns. The three-dimensional structure includes a ceramic material having an open cell structure with a plurality of pores, where the pores form continuous channels through the ceramic material from one side of the ceramic material to an opposite side of the ceramic material.
FILED Friday, December 06, 2019
APPL NO 16/706526
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/62 (20130101)
B01D 53/80 (20130101)
B01D 53/228 (20130101)
B01D 53/229 (20130101)
B01D 67/0079 (20130101)
B01D 69/141 (20130101)
B01D 71/024 (20130101)
B01D 2251/304 (20130101)
B01D 2251/606 (20130101)
B01D 2257/504 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/06 (20130101) Original (OR) Class
B01J 20/041 (20130101)
B01J 20/3007 (20130101)
B01J 20/3064 (20130101)
B01J 20/3078 (20130101)
B01J 20/3204 (20130101)
B01J 20/3287 (20130101)
B01J 20/3433 (20130101)
B01J 20/3483 (20130101)
B01J 20/28045 (20130101)
B01J 20/28085 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/10 (20200101)
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11638911 Suib et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) University of Connecticut (Farmington, Connecticut)
ASSIGNEE(S) UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
INVENTOR(S) Steven L. Suib (Storrs, Connecticut);  Wimalika Rasangi Kumari Thalgaspitiya (Vernon, Connecticut);  Tharindu M. P. K. Kapuge (Vernon, Connecticut)
ABSTRACT The present disclosure relates to mesoporous metal titanate materials composition. Specifically, the present disclosure relates to a mesoporous metal titanate material composition that is active for multiple reactions, including aromatic alkylation, alkene coupling, alkene cyclization, alkyne oxidation, alcohol dehydrogenation reactions.
FILED Tuesday, February 18, 2020
APPL NO 16/793669
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/02 (20130101)
B01J 23/06 (20130101)
B01J 23/10 (20130101)
B01J 23/18 (20130101)
B01J 23/22 (20130101)
B01J 23/28 (20130101)
B01J 23/30 (20130101)
B01J 23/34 (20130101)
B01J 23/72 (20130101)
B01J 23/75 (20130101)
B01J 23/745 (20130101)
B01J 23/755 (20130101) Original (OR) Class
B01J 35/1019 (20130101)
B01J 35/1023 (20130101)
B01J 35/1038 (20130101)
B01J 35/1042 (20130101)
B01J 35/1061 (20130101)
B01J 35/1085 (20130101)
B01J 37/04 (20130101)
B01J 37/06 (20130101)
B01J 37/0018 (20130101)
B01J 37/088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11638970 Matthews
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Manyalibo Joseph Matthews (Livermore, California)
ABSTRACT The present disclosure relates to a laser based system for laser peening a workpiece. The system has a pulse laser configured to generate laser pulses and a controller for controlling operation of the pulse laser. The controller is further configured to control the pulse laser to cause the pulse laser to generate at least one of the laser pulses with a spatio-temporally varying laser fluence over a duration of the at least one of the laser pulses.
FILED Tuesday, September 24, 2019
APPL NO 16/580141
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/073 (20130101)
B23K 26/356 (20151001) Original (OR) Class
B23K 26/0608 (20130101)
B23K 26/0622 (20151001)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639010 Geelhoed
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Fermi National Accelerator Laboratory (FNAL)
Federally Funded Research and Development Center (FFRDC)
Operated by Fermi Research Alliance, LLC (FRA) at Batavia, IL
APPLICANT(S) Fermi Research Alliance, LLC (Batavia, Illinois)
ASSIGNEE(S) FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois)
INVENTOR(S) Michael Geelhoed (Batavia, Illinois)
ABSTRACT A system and method for the treatment of invasive pests includes an irradiation device that can generate an electron beam that is applicable to a tree infected by an invasive pest, wherein the electron beam provides an in-situ treatment for the tree infected by the invasive pest by killing the invasive pest via electron beam irradiation. One or more temperature sensors can be used to track the internal temperature of a tree surrogate. A differential temperature difference tracked by temperature sensor can be used to ensure that a reduction in temperature of the tree is attributable to the electron beam rather than increase in heat.
FILED Tuesday, July 07, 2020
APPL NO 16/923059
ART UNIT 2876 — Optics
CURRENT CPC
Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants
A01M 1/226 (20130101)

Processes, Apparatus or Selection of Substances for Impregnating, Staining, Dyeing, Bleaching of Wood or Similar Materials, or Treating of Wood or Similar Materials With Permeant Liquids, Not Otherwise Provided for; Chemical or Physical Treatment of Cork, Cane, Reed, Straw or Similar Materials
B27K 5/0035 (20130101) Original (OR) Class

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 3/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639031 Shusteff et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Maxim Shusteff (Piedmont, California);  James Oakdale (Castro Valley, California);  Robert Matthew Panas (Dublin, California);  Christopher M. Spadaccini (Oakland, California);  Hayden K. Taylor (Berkeley, California);  Brett Kelly (Berkeley, California);  Indrasen Bhattacharya (Berkeley, California);  Hossein Heidari (Berkeley, California)
ABSTRACT Methods and materials for volumetric additive manufacturing, including computed axial lithography (“CAL”), using photosensitive resins comprising a photocurable resin prepolymer; a photoinitiator; and (optionally) a curing inhibitor. In various embodiments, such photosensitive polymers comprise (a) one or more monomer (or prepolymer) molecules, which form the backbone of the polymer network of the polymeric material and define its architecture; and (b) a photoinitiator that captures illumination energy and initiates polymerization.
FILED Wednesday, May 13, 2020
APPL NO 15/930822
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/106 (20170801)
B29C 64/124 (20170801)
B29C 64/153 (20170801)
B29C 64/232 (20170801)
B29C 64/241 (20170801)
B29C 64/264 (20170801)
B29C 64/268 (20170801)
B29C 64/277 (20170801)
B29C 64/282 (20170801)
B29C 64/386 (20170801)
B29C 64/393 (20170801) Original (OR) Class

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2033/08 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 40/20 (20200101)
B33Y 50/02 (20141201)
B33Y 70/10 (20200101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 2/50 (20130101)
C08F 20/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639304 Gangloff, Jr. et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
INVENTOR(S) John J. Gangloff, Jr. (Middletown, Connecticut);  Paul Sheedy (Bolton, Connecticut);  Rajiv Ranjan (South Windsor, Connecticut)
ABSTRACT A method of fabricating a glass matrix composite includes providing a fiber preform in a cavity of a die tooling, the fiber preform circumscribing an interior region; providing a parison of glass matrix material in the interior region, the glass matrix material having a first viscosity; introducing pressurized inert gas into the parison to outwardly inflate the parison against the fiber preform; and while under pressure from the pressurized inert gas, decreasing the first viscosity of the glass matrix material to a second viscosity. The pressure and the second viscosity cause the glass matrix material to flow and infiltrate into the fiber preform to thereby form a consolidated workpiece. The consolidated workpiece is then cooled to form a glass matrix composite.
FILED Friday, February 07, 2020
APPL NO 16/784384
ART UNIT 1759 — Material and Article Handling
CURRENT CPC
Manufacture, Shaping, or Supplementary Processes
C03B 9/347 (20130101) Original (OR) Class

Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 10/00 (20130101)
C03C 14/002 (20130101)
C03C 2214/20 (20130101)
C03C 2214/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639506 Piotrowski et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Jeff Scott Piotrowski (Madison, Wisconsin);  Scott Bottoms (Madison, Wisconsin);  Quinn Dickinson (Madison, Wisconsin);  Robert Chase Landick (Madison, Wisconsin)
ABSTRACT The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified strains of Saccharomyces cerevisiae having enhanced tolerance for ionic liquid (IL) toxicity. Also provided are methods of using such genetically engineered yeast strains for improved IL-mediated hydrolysis of lignocellulosic biomass for industrial-scale production of various fuels, chemical feedstocks, and synthetic polymers.
FILED Friday, May 13, 2016
APPL NO 15/154537
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/81 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/10 (20130101)
C12P 19/02 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639903 Miller et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Erin A. Miller (Richland, Washington);  Richard E. Jacob (Kennewick, Washington);  Nikhil S. Deshmukh (Everett, Washington);  Cynthia L. Warner (Richland, Washington);  Richard S. Wittman (Richland, Washington);  Luke W. Campbell (Richland, Washington);  Dustin M. Kasparek (Richland, Washington);  Andy Gilbert (Richland, Washington);  Stanley L. Owsley, Jr. (Pasco, Washington);  Kurt L. Silvers (Pasco, Washington);  Mital A. Zalavadia (Richland, Washington)
ABSTRACT Method include emitting x-rays from an x-ray source, directing a first portion of the x-rays through an object grating situated adjacent to an object while the object is scanned relative to the object grating along a scan direction, directing a second portion of the x-rays through the object and subsequently through a detector grating without transmitting through the object grating, wherein the object grating and detector grating are adjacently arranged in a field of view of the x-rays sequentially with respect to each other in the scan direction, and receiving the first portion transmitted through the object and object grating with a first portion of a detector and receiving the second portion transmitted through the object and the detector grating with a second portion of the detector adjacent to the first portion of the detector. Systems are also disclosed, along with related techniques for beam hardening correction.
FILED Monday, May 17, 2021
APPL NO 17/322635
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/06 (20130101)
A61B 6/484 (20130101)
A61B 6/4035 (20130101)
A61B 6/4291 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/10 (20130101)
G01N 23/18 (20130101)
G01N 23/041 (20180201) Original (OR) Class
G01N 23/083 (20130101)
G01N 2223/316 (20130101)
G01N 2223/401 (20130101)
G01N 2223/424 (20130101)
G01N 2223/3307 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639975 Shi et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jing Shi (Riverside, California);  Junxue Li (Riverside, California)
ABSTRACT Systems and methods for spin-based detection of electromagnetic radiation at terahertz and sub-terahertz frequencies is provided. The detector can include a heterostructure, a magnetic field generator, and an electrical circuit. The heterostructure can include a first layer formed of an antiferromagnetic material (AFM) in contact with a second layer of a heavy metal (HM) or a topological insulator. The magnetic field generator can generate a magnetic field oriented approximately parallel to an easy axis of the first layer and approximately parallel to a propagation direction of electromagnetic radiation. The circuit can be in electrical communication with the second layer. The first layer can inject a spin current into the second layer in response to receipt of electromagnetic radiation having a sub-terahertz or terahertz frequency. The second layer can convert the injected spin current into a potential difference. The circuit can be configured to output a signal corresponding to the potential difference.
FILED Monday, September 14, 2020
APPL NO 17/020796
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/3586 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/075 (20130101)
G01R 33/1284 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 43/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11641185 McIntyre
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oakridge, Tennessee)
INVENTOR(S) Timothy J. McIntyre (Farragut, Tennessee)
ABSTRACT A method of making an acoustic wave sensor includes the steps of providing a piezoelectric substrate layer and printing on the substrate layer a sensor layer comprising a first interdigitated acoustic wave transducer, a sensing film, and positioned on an opposing side of the sensing film from the first interdigitated acoustic wave transducer at least one selected from the group consisting of a second interdigitated acoustic wave transducer and a Bragg reflector. An insulation layer can be printed. An antenna can be printed in an antenna layer, and the insulation layer can be interposed between the antenna layer and the sensor layer. An electrical connection can be printed between the antenna and the first interdigitated acoustic wave transducer. An acoustic wave sensor is also disclosed.
FILED Tuesday, March 26, 2019
APPL NO 16/365252
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/022 (20130101)
G01N 29/22 (20130101)
G01N 2291/0255 (20130101)
G01N 2291/0256 (20130101)
G01N 2291/0423 (20130101)
G01N 2291/0426 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 9/02007 (20130101)
H03H 9/02275 (20130101)
H03H 9/02535 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11641282 Murialdo et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Maxwell R. Murialdo (Westminster, California);  Brian Giera (San Mateo, California);  Brian M. Howell (Livermore, California);  Robert M. Panas (Dublin, California)
ABSTRACT Systems and methods performed for generating authentication information for an image using optical computing are provided. When a user takes a photo of an object, an optical authentication system receives light reflected and/or emitted from the object. The system also receives a random key from an authentication server. The system converts the received light to plenoptic data and uploads it to the authentication server. In addition, the system generates an optical hash of the received light using the random key, converts the generated optical hash to a digital optical hash, and uploads the digital optical hash to the authentication server. When the authentication server receives the upload, it verifies whether the time of the upload is within a certain threshold time from the sending of the random key and whether the digital optical hash was generated from the same light as the plenoptic data.
FILED Thursday, May 27, 2021
APPL NO 17/332415
ART UNIT 2497 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/10 (20130101)
G06F 21/64 (20130101)
G06F 2221/0733 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Image Data Processing or Generation, in General
G06T 7/0002 (20130101)
G06T 2207/10052 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/50 (20220501)
H04L 9/0643 (20130101)
H04L 9/0819 (20130101)
H04L 9/0877 (20130101)
H04L 9/0894 (20130101)
H04L 9/3236 (20130101) Original (OR) Class
H04L 9/3247 (20130101)
H04L 9/3297 (20130101)

Pictorial Communication, e.g Television
H04N 5/22541 (20180801)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11638603 Sano et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia)
ASSIGNEE(S) Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia)
INVENTOR(S) Michael B. Sano (Durham, North Carolina);  Christopher B. Arena (Burlington, North Carolina);  Scott S. Verbridge (Blacksburg, Virginia);  Rafael V. Davalos (Blacksburg, Virginia)
ABSTRACT The present invention relates to the field of biomedical engineering and medical treatment of diseases and disorders. Methods, devices, and systems for in vivo treatment of cell proliferative disorders are provided. In embodiments, the methods comprise the delivery of high-frequency bursts of bipolar pulses to achieve the desired modality of cell death. More specifically, embodiments of the invention relate to a device and method for destroying aberrant cells, including tumor tissues, using high-frequency, bipolar electrical pulses having a burst width on the order of microseconds and duration of single polarity on the microsecond to nanosecond scale. In embodiments, the methods rely on conventional electroporation with adjuvant drugs or irreversible electroporation to cause cell death in treated tumors. The invention can be used to treat solid tumors, such as brain tumors.
FILED Monday, June 17, 2019
APPL NO 16/443351
ART UNIT 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/14 (20130101) Original (OR) Class
A61B 2018/0016 (20130101)
A61B 2018/00577 (20130101)
A61B 2018/00613 (20130101)
A61B 2018/00761 (20130101)
A61B 2018/00767 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/327 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639425 Lee et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Daeyeon Lee (Wynnewood, Pennsylvania);  Yun-Ru Huang (Philadelphia, Pennsylvania);  Shu Yang (Blue Bell, Pennsylvania);  Dengteng Ge (Philadelphia, Pennsylvania)
ABSTRACT A method of producing a nanocomposite film includes generating a bilayer film including at least a first layer of at least one nanoparticle and a second layer of at least one material and annealing the bilayer film. A uniform nanocomposite film includes a plurality of nanoparticles dispersed in a polymer matrix, wherein the plurality of nanoparticles form at least 60% by volume of the polymer nanocomposite film.
FILED Tuesday, May 12, 2015
APPL NO 15/310172
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/005 (20130101)
B05D 3/067 (20130101)
B05D 3/0209 (20130101)
B05D 3/0254 (20130101)
B05D 5/00 (20130101)
B05D 5/08 (20130101)

Cleaning in General; Prevention of Fouling in General
B08B 17/06 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101) Original (OR) Class
C08J 2325/06 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/22 (20130101)
C08K 2003/2241 (20130101)
C08K 2201/011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639482 Chung et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Yip-Wah Chung (Wilmette, Illinois);  Qian Jane Wang (Mount Prospect, Illinois);  Qiang Ma (Evanston, Illinois);  Arman Mohammad Khan (Evanston, Illinois)
ABSTRACT A lubricant composition includes a base lubricant and a plurality of lubricant additive molecules functioning as precursor molecules to induce tribopolymerization and forming in situ protective tribofilm with desirable robustness and low shear resistance. Each lubricant additive molecule includes one or more surface-active groups attractable to target surface, and a carbon containing component operable connected to the one or more surface active groups. The carbon containing component comprise a carbon ring structure having a high ring strain that is metastable and activatable with a ring-opening reaction. A less stable carbon ring structure is more readily activated to the intermediate state, preferable to form more active fragments. Increasing the adsorption strength further is beneficial to prolonging the residence time of additive molecules on the target surface, thereby facilitating the dissociation of molecules and subsequent polymerization.
FILED Tuesday, April 13, 2021
APPL NO 17/228920
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 129/32 (20130101)
C10M 129/34 (20130101)
C10M 177/00 (20130101) Original (OR) Class
C10M 2207/122 (20130101)
C10M 2207/123 (20130101)

Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions
C10N 2070/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639519 Seelig et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Georg Seelig (Seattle, Washington);  Richard Muscat (London, United Kingdom);  Alexander B. Rosenberg (Seattle, Washington)
ABSTRACT Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
FILED Monday, July 25, 2022
APPL NO 17/814712
ART UNIT 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101) Original (OR) Class
C12Q 1/6855 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639554 Wang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Trustees of Boston College (Chestnut Hill, Massachusetts)
ASSIGNEE(S) The Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S) Dunwei Wang (Newton, Massachusetts);  Qi Dong (Newton, Massachusetts);  Xizi Zhang (Berkeley, California)
ABSTRACT A flow cell for reducing carbon dioxide may include a first chamber having a gold coated gas diffusion layer working electrode, a reference electrode, and a water-in-salt electrolyte comprising a super concentrated aqueous solution of lithium bis-(trifluoromethanesulfonyl)imide (LiTFSI). A second chamber adjacent the first chamber has a gold coated gas diffusion layer counter electrode and the water-in-salt electrolyte. The second chamber being separated from the first chamber by a proton exchange membrane. A reservoir coupled to each of the first and the second chambers with a pump contains a volume of the water-in-salt electrolyte and a head space.
FILED Wednesday, December 16, 2020
APPL NO 17/123578
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 3/26 (20210101) Original (OR) Class
C25B 9/15 (20210101)
C25B 15/025 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11640013 Garrett et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Division of Atmospheric and Geospace Sciences (AGS)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Timothy John Garrett (Salt Lake City, Utah);  Florian Solzbacher (Salt Lake City, Utah);  Konstantin Shkurko (Salt Lake City, Utah)
ABSTRACT A weather-detecting device (100) can include a substrate (102) and a detection region (106) exposed to an environment within which the weather-detecting device (100) is situated when in use. An array (110) of heating elements (112) can be mounted at a first side of the substrate (102), with at least one surface of each heating element (112) in the array (110) being positioned within the detection region (106). A controller can be electrically coupled to the array (110) of heating elements (112), and the controller can individually address each heating element (112) in the array (110) to selectively pass electrical current through each heating element (112).
FILED Monday, October 15, 2018
APPL NO 16/755812
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Meteorology
G01W 1/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11640014 Hihath et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Joshua Hihath (Woodland, California);  Omeed Momeni (Davis, California);  Davide Donadio (Davis, California)
ABSTRACT Various metamaterials are disclosed. An example metamaterial comprises: a first portion with a plurality of nanoparticles; a second portion with a plurality of molecules configured to interlink with the plurality of nanoparticles; and a signal generator configured to provide a signal to the material. The first portion and the second portion of the material are configured to form a hybrid molecule-nanoparticle super-lattice. In some implementations, the first portion of the material is configured to have a mass configured to achieve, at least in part, a designated resonance frequency. The second portion of the material is, in some implementations, configured to have a molecular stiffness configured to achieve, at least in part, the designated resonance frequency. The signal generator is, in some implementations, configured to generate radio frequency (RF) signals.
FILED Monday, September 28, 2020
APPL NO 17/034091
ART UNIT 2871 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/005 (20130101) Original (OR) Class
G02B 2207/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11640464 Yavuz et al.
FUNDED BY
Non-Profit Organization (NPO)
Semiconductor Research Corporation (SRC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Tuba Yavuz (Gainesville, Florida);  Farhaan Fowze (Gainesville, Florida);  Kevin Raymond Boyce Butler (Gainesville, Florida);  Jing Tian (Gainesville, Florida);  Grant Haydock Hernandez (Gainesville, Florida)
ABSTRACT The present disclosure describes a firmware analysis system and method that can generate a collection of protocol constraints from known firmware and apply the collection of protocol constraints towards an unknown firm to recognize protocol relevant fields and detect functionality within the unknown firmware.
FILED Thursday, May 30, 2019
APPL NO 16/426691
ART UNIT 2492 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/562 (20130101) Original (OR) Class
G06F 2221/033 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11638904 Glover et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Thomas Grant Glover (Spanish Fort, Alabama);  Stephen Michael Christopher Ritchie (Northport, Alabama)
ASSIGNEE(S) The University of South Alabama (Mobile, Alabama);  The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama)
INVENTOR(S) Thomas Grant Glover (Spanish Fort, Alabama);  Stephen Michael Christopher Ritchie (Northport, Alabama)
ABSTRACT A method of encapsulating an engineered pellet in a porous membrane is disclosed. The method includes the steps of: (i) dissolving a membrane solute in a membrane solvent to produce a membrane solution; (ii) applying the membrane solution to a pellet to form a pellet encapsulated with the membrane solution; (iii) subjecting the membrane solution that encapsulates the pellet to a phase inversion and; (iv) drying the pellet to form a porous membrane encapsulated pellet. A porous membrane encapsulated pellet is also described.
FILED Tuesday, December 15, 2020
APPL NO 17/121974
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/08 (20130101)
B01D 53/1475 (20130101)
B01D 67/0002 (20130101)
B01D 69/141 (20130101) Original (OR) Class
B01D 2325/02 (20130101)
B01D 2325/14 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/226 (20130101)
B01J 20/262 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11640013 Garrett et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Division of Atmospheric and Geospace Sciences (AGS)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Timothy John Garrett (Salt Lake City, Utah);  Florian Solzbacher (Salt Lake City, Utah);  Konstantin Shkurko (Salt Lake City, Utah)
ABSTRACT A weather-detecting device (100) can include a substrate (102) and a detection region (106) exposed to an environment within which the weather-detecting device (100) is situated when in use. An array (110) of heating elements (112) can be mounted at a first side of the substrate (102), with at least one surface of each heating element (112) in the array (110) being positioned within the detection region (106). A controller can be electrically coupled to the array (110) of heating elements (112), and the controller can individually address each heating element (112) in the array (110) to selectively pass electrical current through each heating element (112).
FILED Monday, October 15, 2018
APPL NO 16/755812
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Meteorology
G01W 1/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11639279 Perry-Eaton et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Wayne Perry-Eaton (Leesburg, Virginia);  George W. Potts, Jr. (Upper Marlboro, Maryland);  Daniel Radtke (Madison, Wisconsin)
ABSTRACT An automated system for transferring articles from a container. An item transfer system includes retainers configured to secure a first tray and a second tray, a movable paddle assembly, a frame, and a plurality of actuators. The system is configured to transfer articles from the first tray to the second tray by an automated process including securing the articles within the first tray with the paddle assembly, rotating the frame by approximately 90° to 100°, moving the paddle assembly in a series of linear translations to remove the items from the first tray and place the items into the second tray, rotating the frame back to its initial orientation, and releasing the items into the second tray.
FILED Monday, June 06, 2022
APPL NO 17/805655
ART UNIT 3652 — Material and Article Handling
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/087 (20130101)

Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors
B65G 1/137 (20130101)

Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables
B65H 1/027 (20130101)
B65H 5/006 (20130101)
B65H 15/02 (20130101) Original (OR) Class
B65H 29/02 (20130101)
B65H 2301/42242 (20130101)
B65H 2301/422542 (20130101)
B65H 2301/422548 (20130101)
B65H 2701/1916 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11639854 Bonnell et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Clayton C. Bonnell (Fairfax, Virginia);  Neri G. Terry (Springfield, Virginia);  Kurt J. Schulz (Ballwin, Missouri)
ABSTRACT A method and system for generating a location identification grid and for using a location identification grid. The location identification grid can include a first geographic area that correspond to a pre-existing area. This pre-existing area can correspond to a postal code such as a zip code, a telephone code such as, an area code, or any other desired pre-existing area. The location identification grid can be subdivided into smaller geographic areas to allow more accurate identification of a location. The location identification grid can include a second geographic area. The second geographic area can be a subdivision of the first geographic area. The location identification grid can be used with signals that identify a location within a location identification grid. These signals can include a first component corresponding to the first geographic area and the second component corresponding to one or more second geographic areas.
FILED Friday, February 19, 2021
APPL NO 17/180584
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/20 (20130101)
G01C 21/34 (20130101) Original (OR) Class
G01C 21/3667 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 29/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US PP35144 Chen et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Chunxian Chen (Byron, Georgia);  William R. Okie (Augusta, Georgia)
ABSTRACT A new and distinct cultivar of peach tree, denominated ‘Cardinal Joy’, has firm, melting, semi-freestone fruit with a high coverage of red blush, yellow flesh, normal acidity, rich flavor and pleasant eating quality at maturity. The fruit typically ripen about a week after ‘Flavorich’ (syn. ‘Rich May’) and a few days before ‘Carored’ in mid to late May at Byron, Ga. The tree has self-fertile showy pink flowers and is moderately vigorous and semi-spreading in growth habit. This cultivar has a winter chilling requirement of approximately 850 chill hours, crops well most years, and is suited for high chill areas.
FILED Friday, August 05, 2022
APPL NO 17/881660
ART UNIT 1661 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 6/7463 (20180501) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11638522 Abramoff et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Michael D. Abramoff (University Heights, Iowa);  Meindert Niemeijer (Iowa City, Iowa);  Xiayu Xu (Iowa City, Iowa);  Milan Sonka (Coralville, Iowa);  Joseph M. Reinhardt (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa);  United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Michael D. Abramoff (University Heights, Iowa);  Meindert Niemeijer (Iowa City, Iowa);  Xiayu Xu (Iowa City, Iowa);  Milan Sonka (Coralville, Iowa);  Joseph M. Reinhardt (Iowa City, Iowa)
ABSTRACT The methods and systems provided can automatically determine an Arteriolar-to-Venular diameter Ratio, AVR, in blood vessels, such as retinal blood vessels and other blood vessels in vertebrates. The AVR is an important predictor of increases in the risk for stroke, cerebral atrophy, cognitive decline, and myocardial infarct.
FILED Monday, March 26, 2018
APPL NO 15/936162
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/12 (20130101) Original (OR) Class
A61B 3/0016 (20130101)
A61B 3/0058 (20130101)
A61B 3/1225 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11640524 Mountain
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) The Government of the United States as represented by the Director, National Security Agency (Ft George G Meade, Maryland)
ASSIGNEE(S) The Government of the United States as represented by the Director, National Security Agency (Ft. George G. Meade, Maryland)
INVENTOR(S) David J Mountain (Baltimore, Maryland)
ABSTRACT A computer processor includes an on-chip network and a plurality of tiles. Each tile includes an input circuit to receive a voltage signal from the network, and a crossbar array, including at least one neuron. The neuron includes first and second bit lines, a programmable resistor connecting the voltage signal to the first bit line, and a comparator to receive inputs from the two bit lines and to output a voltage, when a bypass condition is not active. Each tile includes a programming circuit to set a resistance value of the resistor, a pass-through circuit to provide the voltage signal to an input circuit of a first additional tile, when a pass-through condition is active, a bypass circuit to provide values of the bit lines to a second additional tile, when the bypass condition is active; and at least one output circuit to provide an output signal to the network.
FILED Friday, August 27, 2021
APPL NO 17/459079
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/084 (20130101)
G06N 3/0635 (20130101) Original (OR) Class

Static Stores
G11C 13/0069 (20130101)

Amplifiers
H03F 3/45269 (20130101)

Pulse Technique
H03K 5/2481 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11640464 Yavuz et al.
FUNDED BY
Non-Profit Organization (NPO)
Semiconductor Research Corporation (SRC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Tuba Yavuz (Gainesville, Florida);  Farhaan Fowze (Gainesville, Florida);  Kevin Raymond Boyce Butler (Gainesville, Florida);  Jing Tian (Gainesville, Florida);  Grant Haydock Hernandez (Gainesville, Florida)
ABSTRACT The present disclosure describes a firmware analysis system and method that can generate a collection of protocol constraints from known firmware and apply the collection of protocol constraints towards an unknown firm to recognize protocol relevant fields and detect functionality within the unknown firmware.
FILED Thursday, May 30, 2019
APPL NO 16/426691
ART UNIT 2492 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/562 (20130101) Original (OR) Class
G06F 2221/033 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 11641194 Whiteley
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) Synopsys, Inc. (Mountain View, California)
ASSIGNEE(S) Synopsys, Inc. (Mountain View, California)
INVENTOR(S) Stephen Robert Whiteley (Sunnyvale, California)
ABSTRACT A circuit can include a first sub-circuit, a second sub-circuit, and a third sub-circuit. The first sub-circuit can store a reset state or a set state, and can include a first Josephson junction (JJ), a second JJ, and a third JJ coupled in parallel using superconducting inductors. The first JJ, the second JJ, and the third JJ can be biased using a JJ-based current source. The second sub-circuit can switch the first sub-circuit to the set state in response to receiving a pulse. The third sub-circuit can switch the first sub-circuit to the reset state in response to receiving one or more pulses.
FILED Friday, July 10, 2020
APPL NO 16/926385
ART UNIT 2849 — Printing/Measuring and Testing
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 39/22 (20130101)
H01L 39/223 (20130101)

Pulse Technique
H03K 3/38 (20130101) Original (OR) Class
H03K 19/1954 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11640655 Hayes et al.
FUNDED BY
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) RAYTHEON COMPANY (Waltham, Massachusetts)
INVENTOR(S) Matthew John Francis Hayes (McKinney, Texas);  Dustin Hamill (McKinney, Texas);  James Robarge (McKinney, Texas);  Christopher Beardsley (McKinney, Texas);  Carl Magnuson (McKinney, Texas)
ABSTRACT A system, and method of operating the same detects moving targets in images and performs image turbulence correction. The system includes an automatic target recognizer (ATR) system including a database. The ATR includes a feature extractor and processor arranged to detect a plurality of reference features associated with targets within image frames, and calculate a position of the plurality of reference features. The system includes an image processor arranged to receive the position, demosaic the image frames into a plurality of video tiles, iteratively process the video tiles for turbulence correction to generate turbulence corrected video tiles associated with acquired targets; convert the turbulence corrected video tiles into a single video frame tile including turbulence degradation correction; and mosaic each of the single video frame tiles to generate a full field of view turbulence corrected video stream.
FILED Wednesday, April 14, 2021
APPL NO 17/230621
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/9021 (20190501)
G01S 17/89 (20130101)

Image Data Processing or Generation, in General
G06T 3/4038 (20130101)
G06T 5/003 (20130101) Original (OR) Class
G06T 7/246 (20170101)
G06T 2207/10024 (20130101)
G06T 2207/10048 (20130101)
G06T 2207/20132 (20130101)
G06T 2207/30196 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11641269 Robinson
FUNDED BY
APPLICANT(S) Rampart Communications, Inc. (Annapolis, Maryland)
ASSIGNEE(S) Rampart Communications, Inc. (Linthicum Heights, Maryland)
INVENTOR(S) Matthew Brandon Robinson (Crownsville, Maryland)
ABSTRACT A method for implementing a fast UBDM transform includes receiving a first, input vector via a processor, and partitioning the first vector to produce a magnitude vector and a sign vector. A second vector, including a modified magnitude vector and a modified sign vector, is generated by: applying a permutation to the magnitude vector to produce the modified magnitude vector, converting the sign vector, based on an algorithm, into an intermediate sign vector, and applying nonlinear layers to the intermediate sign vector. Each nonlinear layer includes a permutation, an S-box transformation, a diffusive linear operation and/or an Xor operation. Multiple linear layers are applied to the second vector to produce a third vector, the third vector being a transformed version of the first vector. A first signal representing the third vector is sent to at least one transmitter for transmission of a second signal representing the transformed data vector.
FILED Tuesday, June 30, 2020
APPL NO 16/916303
ART UNIT 2433 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0637 (20130101) Original (OR) Class
H04L 27/2627 (20130101)
H04L 2209/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, May 02, 2023.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230502.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital