FedInvent™ Patents
Patent Details for Tuesday, May 09, 2023
This page was updated on Wednesday, May 10, 2023 at 05:15 AM GMT
Department of Health and Human Services (HHS)
| US 11642057 | Berthier et al. |
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| FUNDED BY |
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| APPLICANT(S) | Tasso, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | Tasso, Inc. (Seattle, Washington) |
| INVENTOR(S) | Erwin Berthier (Seattle, Washington); Ben Casavant (Seattle, Washington); Ben Moga (Soquel, California) |
| ABSTRACT | The disclosed apparatus, systems and methods relate to devices, systems and methods for the collection of bodily fluids involving a single-use actuation and retraction mechanism disposed within a collector. |
| FILED | Wednesday, August 28, 2019 |
| APPL NO | 16/554246 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/15113 (20130101) A61B 5/15115 (20130101) Original (OR) Class A61B 5/15117 (20130101) A61B 5/15144 (20130101) A61B 5/150022 (20130101) A61B 5/150099 (20130101) A61B 5/150167 (20130101) A61B 5/150175 (20130101) A61B 5/150221 (20130101) A61B 5/150236 (20130101) A61B 5/150908 (20130101) A61B 5/150916 (20130101) A61B 5/150984 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642100 | Fatemi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Mostafa Fatemi (Rochester, Minnesota); Azra Alizad (Rochester, Minnesota); Marek Belohlavek (Scottsdale, Arizona); Viksit Kumar (Rochester, Minnesota) |
| ABSTRACT | Described here are systems and method for using ultrasound to localize a medical device to which an active ultrasound element that can transmits ultrasound energy is attached. Doppler signal data of the medical device are acquired while the active element is transmitting acoustic energy, and the Doppler signal data are processed to detect symmetric Doppler shifts associated with the active element. The systems and methods described in the present disclosure enable tracking and display of one or more locations on or associated with the medical device. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/577194 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7257 (20130101) A61B 8/488 (20130101) A61B 8/0841 (20130101) A61B 8/4245 (20130101) Original (OR) Class A61B 8/4488 (20130101) A61B 90/37 (20160201) A61B 2034/2063 (20160201) A61B 2090/364 (20160201) A61B 2090/378 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642143 | Kallmes et al. |
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| FUNDED BY |
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| APPLICANT(S) | Covidien LP (Mansfield, Massachusetts); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | COVIDIEN LP (Mansfield, Massachusetts); MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
| INVENTOR(S) | David F. Kallmes (Rochester, Minnesota); Waleed Brinjikji (Rochester, Minnesota); Brady Hatcher (Rogers, Minnesota); Randy Beyreis (Rogers, Minnesota) |
| ABSTRACT | A balloon guiding sheath may include an elongated sheath comprising a proximal end, a distal end, an inner tube, an outer tube surrounding the inner tube, an access port, a distal port, and a working lumen extending through an interior portion of the elongated sheath between the access port and the distal port. The balloon guiding sheath may also include an inflatable balloon located on an outer surface of the elongated sheath adjacent the distal end. The balloon guiding sheath may include a plurality of inflation holes extending through a side wall of the elongated sheath. The elongated sheath may be sized and configured to enable direct insertion into a patient's vasculature through an arteriotomy in at least one of a femoral artery and vertebral artery to position the inflatable balloon at a target site. |
| FILED | Monday, April 05, 2021 |
| APPL NO | 17/222392 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/22 (20130101) Original (OR) Class A61B 2017/22065 (20130101) A61B 2017/22079 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/1018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642232 | McDonnall et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ripple, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | Ripple LLC (Salt Lake City, Utah) |
| INVENTOR(S) | Daniel Allen McDonnall (Salt Lake City, Utah); Scott Darold Hiatt (South Jordan, Utah); Brian Scott Crofts (Salt Lake City, Utah); Christopher Farand Smith (North Salt Lake, Utah); Andrew Miller Wilder (Salt Lake City, Utah) |
| ABSTRACT | Disclosed herein are systems and methods for sensor systems. In one embodiment, a system may include an implantable component and an external component. The implantable component may comprise a housing and an electrode array configured to receive a plurality of biopotential signals. The housing may comprise a wireless power receiver and a wireless data transmitter to transmit representations of the biopotential signals. The external component may comprise a wireless data receiver configured to receive the plurality of digital representations of the biopotential signals and a wireless power transmitter configured to provide power to the internal component. A shielding component may separate the wireless power transmitter from the wireless data receiver. An interface may be configured to communicate with a prosthesis and configured to cause the prosthesis to implement a voluntary motion based on the plurality of digital presentations of the biopotential signals. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 16/869248 |
| ART UNIT | 2683 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0017 (20130101) A61B 5/0031 (20130101) A61B 5/296 (20210101) A61B 5/389 (20210101) A61B 2560/0214 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Original (OR) Class A61F 2002/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642317 | Popov et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Alexey Popov (Waltham, Massachusetts); Elizabeth M. Enlow (Waltham, Massachusetts); James Bourassa (Somerville, Massachusetts); Colin R. Gardner (Concord, Massachusetts); Hongming Chen (Belmont, Massachusetts); Laura M. Ensign (Towson, Maryland); Samuel K. Lai (Carrboro, North Carolina); Tao Yu (Baltimore, Maryland); Justin Hanes (Baltimore, Maryland); Ming Yang (Towson, Maryland) |
| ABSTRACT | Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP) without any polymeric carriers, or with minimal use of polymeric carriers. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles formed of pharmaceutical agents that have a low water solubility. Such methods and compositions can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier. |
| FILED | Wednesday, July 08, 2020 |
| APPL NO | 16/923980 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/10 (20130101) A61K 9/5031 (20130101) Original (OR) Class A61K 9/5089 (20130101) A61K 9/5138 (20130101) A61K 31/12 (20130101) A61K 31/56 (20130101) A61K 31/58 (20130101) A61K 31/341 (20130101) A61K 31/405 (20130101) A61K 31/409 (20130101) A61K 31/496 (20130101) A61K 31/522 (20130101) A61K 31/569 (20130101) A61K 31/573 (20130101) A61K 31/635 (20130101) A61K 31/662 (20130101) A61K 31/675 (20130101) A61K 47/34 (20130101) A61K 49/0089 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642354 | Slaga et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, the University of Texas System (, None) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Thomas J. Slaga (San Antonio, Texas); Jacob Junco (San Antonio, Texas); Huiyun Liang (San Antonio, Texas); Sara Reyna (San Antonio, Texas) |
| ABSTRACT | Certain embodiments are directed to methods and compositions for treating obesity, diabetes, and/or cancer with a combination of ursolic acid and resveratrol. |
| FILED | Saturday, April 17, 2021 |
| APPL NO | 17/233456 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/05 (20130101) A61K 31/05 (20130101) A61K 31/19 (20130101) A61K 31/19 (20130101) A61K 31/56 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642366 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | GLYCOMIRA THERAPEUTICS, INC. (Salt Lake City, Utah) |
| ASSIGNEE(S) | GLYCOMIRA THERAPEUTICS, INC. (Salt Lake City, Utah) |
| INVENTOR(S) | Won Yong Lee (Bountiful, Utah); Abigail Pulsipher (Salt Lake City, Utah); Thomas P. Kennedy (Charlotte, North Carolina); Justin Rodney Savage (North Salt Lake, Utah); Glenn Prestwich (Spokane, Washington) |
| ABSTRACT | Described herein are methods for preventing a serious health consequence and/or tissue damage in a subject after the subject has been exposed to ionizing radiation and/or chemotherapy. The methods involve administering to the subject a sulfated polysaccharide or the pharmaceutically acceptable salt or ester thereof after the subject has been exposed to ionizing radiation and/or chemotherapy. The methods described herein are most beneficial to cancer patients who suffer from mucositis after exposure to ionizing radiation. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 17/059982 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/727 (20130101) Original (OR) Class A61K 31/728 (20130101) A61K 31/737 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642371 | Seto et al. |
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| FUNDED BY |
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| APPLICANT(S) | ADVANTAGE SILVER DENTAL ARREST, LLC (Salem, Oregon) |
| ASSIGNEE(S) | ADVANTAGE SILVER DENTAL ARREST, LLC (Salem, Oregon) |
| INVENTOR(S) | Jong Seto (San Francisco, California); Peter M. Milgrom (Seattle, Washington) |
| ABSTRACT | The invention provides compositions and methods that comprise encapsulated silver diamine fluoride or other antimicrobial materials for use in treatment of dental caries, for example. |
| FILED | Tuesday, December 01, 2020 |
| APPL NO | 17/108947 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/501 (20130101) A61K 9/5073 (20130101) A61K 9/5089 (20130101) A61K 33/38 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 47/16 (20130101) A61K 47/32 (20130101) A61K 47/34 (20130101) A61K 47/46 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642374 | Moriarity et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota); INTIMA BIOSCIENCE, INC. (New York, New York); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | INTIMA BIOSCIENCE, INC. (New York, New York); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Branden Moriarity (Shoreview, Minnesota); Beau Webber (Coon Rapids, Minnesota); Modassir Choudhry (New York, New York); Steven A. Rosenberg (Potomac, Maryland); Douglas C. Palmer (North Bethesda, Maryland); Nicholas P. Restifo (Chevy Chase, Maryland) |
| ABSTRACT | Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer. |
| FILED | Tuesday, November 06, 2018 |
| APPL NO | 16/182146 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 14/4718 (20130101) C07K 14/7051 (20130101) C07K 14/7158 (20130101) C07K 14/70503 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/87 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642375 | Moriarity et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota); INTIMA BIOSCIENCE, INC. (New York, New York); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | INTIMA BIOSCIENCE, INC. (New York, New York); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Branden Moriarity (Shoreview, Minnesota); Beau Webber (Coon Rapids, Minnesota); Modassir Choudhry (New York, New York); Steven A. Rosenberg (Potomac, Maryland); Douglas C. Palmer (North Bethesda, Maryland); Nicholas P. Restifo (Chevy Chase, Maryland) |
| ABSTRACT | Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer. |
| FILED | Tuesday, November 06, 2018 |
| APPL NO | 16/182189 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 14/4718 (20130101) C07K 14/7051 (20130101) C07K 14/7158 (20130101) C07K 14/70503 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/87 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642391 | Mann et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vascular BioSciences (San Diego, California); Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California); David Mann (San Diego, California); Erkki Ruoslahti (La Jolla, California); Masanobu Komatsu (La Jolla, California) |
| ASSIGNEE(S) | Vascular Biosciences (San Diego, California) |
| INVENTOR(S) | David Mann (San Diego, California); Erkki Ruoslahti (La Jolla, California); Masanobu Komatsu (La Jolla, California) |
| ABSTRACT | Compositions and methods useful for delivery of targeted therapies for pulmonary arterial hypertension, sepsis, cancer and cachexia. The compositions and methods are based on peptide pharmacophores that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. Peptide pharmacophores may selectively target tumor vasculature, regenerating tissue, wounded tissue, inflamed tissue, fibrotic tissue, remodeled tissue, tissue characterized by elevated heparanase levels, and have the ability to internalize into such diseased cells. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 15/502170 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/222 (20130101) A61K 31/222 (20130101) A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/436 (20130101) A61K 31/438 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 38/08 (20130101) A61K 38/12 (20130101) Original (OR) Class A61K 38/55 (20130101) A61K 45/06 (20130101) A61K 47/64 (20170801) A61K 47/643 (20170801) A61K 47/6811 (20170801) A61K 47/6851 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 9/12 (20180101) A61P 11/00 (20180101) A61P 13/12 (20180101) A61P 31/00 (20180101) A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/15 (20130101) G01N 33/5008 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 35/00 (20190201) G16B 35/10 (20190201) G16B 35/20 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/60 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642401 | Masopust, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | David B. Masopust, Jr. (Minneapolis, Minnesota); Vaiva D. Vezys (Minneapolis, Minnesota) |
| ABSTRACT | Provided herein are methods of treating cancer by activating resident memory T cells using one or more antigenic peptides. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/939962 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/395 (20130101) A61K 39/39558 (20130101) A61K 48/0058 (20130101) A61K 48/0066 (20130101) A61K 2039/585 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2710/10032 (20130101) C12N 2760/10034 (20130101) C12N 2760/20234 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642405 | Khader et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); BLUEWILLOW BIOLOGICS (Ann Arbor, Michigan) |
| INVENTOR(S) | Shabaana Abdul Khader (St. Louis, Missouri); Mushtaq Ahmed (St. Louis, Missouri); Ali Fattom (St. Louis, Missouri); Douglas Smith (St. Louis, Missouri); Tarek Hamouda (St. Louis, Missouri) |
| ABSTRACT | The present disclosure relates to compositions and methods for inducing an immune response to a composition of the invention in a subject. Additionally, the present disclosure generally relates to methods for screening for immune response to a composition of the invention. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/624722 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) Original (OR) Class A61K 2039/543 (20130101) A61K 2039/5154 (20130101) A61K 2039/55566 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642409 | Irvine et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Insttute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Darrell J. Irvine (Arlington, Massachusetts); Karl Dane Wittrup (Boston, Massachusetts); Tyson Moyer (Boston, Massachusetts); Yash Agarwal (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides immunomodulatory fusion proteins-metal hydroxide complexes comprising an immunomodulatory domain adsorbed to a metal hydroxide via ligand exchange. The disclosure also features compositions and methods of using the same, for example, to treat cancer. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/857999 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/08 (20130101) A61K 38/20 (20130101) A61K 38/191 (20130101) A61K 38/195 (20130101) A61K 39/3955 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/54 (20130101) C07K 14/521 (20130101) C07K 14/525 (20130101) C07K 16/2809 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642416 | Moynihan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kelly Dare Moynihan (Allston, Massachusetts); Rebecca Lynn Holden (Cambridge, Massachusetts); Darrell J. Irvine (Arlington, Massachusetts); Bradley Lether Pentelute (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides a conjugate comprising an albumin binding peptide and a cargo, compositions for directing cargos to the lymphatic system, and vaccines. The methods of the invention can be used to increase an immune response, or to treat cancer or an infectious disease. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/371367 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0011 (20130101) A61K 39/001192 (20180801) A61K 47/646 (20170801) Original (OR) Class A61K 2039/876 (20180801) A61K 2039/6031 (20130101) A61K 2039/6093 (20130101) A61K 2039/55561 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/76 (20130101) C07K 14/4748 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642419 | Schwendeman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Anna A. Schwendeman (Ann Arbor, Michigan); Yuqing Eugene Chen (Superior Township, Michigan); Yanhong Guo (Ann Arbor, Michigan); Jifeng Zhang (Ann Arbor, Michigan); Wenmin Yuan (Ann Arbor, Michigan); Emily Morin (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to nanoparticles complexed with therapeutic agents configured for treating cardiovascular related disorders, and methods of synthesizing the same. In particular, the present invention is directed to compositions comprising synthetic HDL (sHDL) nanoparticles carrying therapeutic agents configured for treating cardiovascular related disorders, methods for synthesizing such sHDL nanoparticles, as well as systems and methods utilizing such sHDL nanoparticles (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutic agents, imaging agents, and/or targeting agents (e.g., in cardiovascular disease diagnosis and/or therapy, etc.))). |
| FILED | Friday, March 25, 2016 |
| APPL NO | 15/561372 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/5169 (20130101) A61K 31/145 (20130101) A61K 31/192 (20130101) A61K 31/4439 (20130101) A61K 38/49 (20130101) A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 47/6917 (20170801) Original (OR) Class A61K 49/008 (20130101) A61K 49/0032 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642423 | Amin |
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| FUNDED BY |
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| APPLICANT(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Neal Dilip Amin (La Jolla, California) |
| ABSTRACT | The present disclosure relates to nucleic acid promoter sequences that are able to specifically express genes operatively linked to the promoter in brainstem and spinal motor neuron cells, and to methods for using such promoters to selectively express genes in motor neurons in vitro and in vivo. It is based, at least in part, on the discovery that the nucleic acid of SEQ ID NO: 1 functioned as a motor neuron-specific promoter and was successful in expressing transgenes in motor neuron cells in vivo. The present disclosure also relates to compositions that can increase the activity or expression level of miR-218 and to compositions that can decrease the expression of miR-218 target nucleic acids. |
| FILED | Tuesday, June 16, 2020 |
| APPL NO | 16/903257 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 67/0276 (20130101) A01K 2217/052 (20130101) A01K 2217/075 (20130101) A01K 2227/50 (20130101) A01K 2227/105 (20130101) A01K 2267/0318 (20130101) A01K 2267/0393 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 48/0016 (20130101) A61K 48/0066 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2310/113 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642487 | Heimbuch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| INVENTOR(S) | Brian K. Heimbuch (Albuquerque, New Mexico); Delbert A. Harnish (Albuquerque, New Mexico); Geoffrey A. Kibble (Albuquerque, New Mexico); Thomas B. Stephenson (Albuquerque, New Mexico); Sheila J. Nogueira-Prewitt (Albuquerque, New Mexico); Christopher G. Estkowski (Pullman, Michigan); Johnnie H. Copley (Minooka, Illinois); Graham Wilson (Flint, United Kingdom); Chris Ward (St. Asaph, United Kingdom) |
| ABSTRACT | A reusable respirator including a mask adapted for covering and conforming to the face around the nose and a mouth of a user, a strap configured to secure the mask to a face of the user, and a filter component. All components of the respirator are capable of being cleaned, disinfected and sterilized at temperatures in excess of 50° C. An outer surface of the mask is substantially smooth and wettable for easily disinfecting and is shaped with a pair of outer shield portions for housing particulate air filters. The outer shield portions each include a closeable vent through the outer surface that is adapted to provide a user seal check and direct air flow through the outer surface for filtering by the respective particulate air filter, which is adapted to filter at least 95% of airborne particles. |
| FILED | Thursday, October 01, 2020 |
| APPL NO | 17/060970 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/0035 (20130101) A61L 2/206 (20130101) A61L 2202/22 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0605 (20140204) A61M 16/0683 (20130101) A61M 16/1065 (20140204) Original (OR) Class A61M 2202/203 (20130101) A61M 2202/206 (20130101) A61M 2209/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642501 | Ferrante et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Giner, Inc. (Newton, Massachusetts) |
| ASSIGNEE(S) | GINER, INC. (Newton, Massachusetts) |
| INVENTOR(S) | Anthony A. Ferrante (Belmont, Massachusetts); Simon G. Stone (Arlington, Massachusetts) |
| ABSTRACT | Implantable gas delivery device and methods, systems, and devices including same. According to one embodiment, the implantable gas delivery device includes a porous core that permits facile transport of gas throughout its open volume. The porous core has sufficiently high tensile strength to withstand pressurization without significant deformation. The porous core is generally planar and is shaped to include a pair of opposing surfaces and a periphery. Diffusion membranes are fixed to the two opposing surfaces of the porous core. A gas supply tube has one end inserted into the porous core and another end connectable to a gas source. The periphery of the porous core is sealed gas-tight, either with a gasket or by sealing the porous core and/or diffusion membranes. The device may be used to deliver a gas to an implanted cell capsule or to native cells or tissues or may be used to expel waste gas. |
| FILED | Friday, May 04, 2018 |
| APPL NO | 15/971658 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14276 (20130101) A61M 31/002 (20130101) Original (OR) Class A61M 2202/09 (20130101) A61M 2202/0208 (20130101) A61M 2205/04 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 9/17 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642524 | Djalilian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Hamid R. Djalilian (Orange, California); Fan-Gang Zeng (Irvine, California); Harrison Lin (Orange, California) |
| ABSTRACT | An electrical stimulation system that provides for transtympanic stimulation of the inner ear that can be used for safely and effectively treating tinnitus. The electrical stimulation system of the present invention may be fully implantable or partially implantable. The system features an electrode placed on the round window membrane. An external portion provides the power to the electrode, which can stimulate the inner ear via the round window as needed by the patient. The present invention also features methods of treating tinnitus using the electrical stimulation system described herein. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 16/859802 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36038 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642528 | Halpern et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Casey Halpern (Menlo Park, California); Robert C. Malenka (Palo Alto, California); Hemmings Wu (Palo Alto, California) |
| ABSTRACT | The present invention provides, inter alia, methods, apparatus, and systems useful for ameliorating impulse control disorders known to be extremely disabling and common to many neurological and psychiatric conditions using closed-loop (responsive) neuro stimulation. |
| FILED | Wednesday, September 27, 2017 |
| APPL NO | 16/337315 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4064 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/0529 (20130101) A61N 1/36085 (20130101) Original (OR) Class A61N 1/36089 (20130101) A61N 1/36139 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642642 | Oakey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| INVENTOR(S) | John Oakey (Laramie, Wyoming); Katie Dongmei Li-Oakey (Laramie, Wyoming); Daniel Debroy (Laramie, Wyoming); Carl Frick (Laramie, Wyoming); Rajib Shaha (Laramie, Wyoming) |
| ABSTRACT | Described are methods and devices for the generation of hydrogel particles with micrometer and submicrometer dimensions using oxygen-inhibited partial polymerization, and the particles generated therefrom. The described methods generate particles with dimensions independent of the starting polymerizable solution dimension, for example, a microdroplet. Further, microfluidic flow parameters (e.g. viscosity, flow rate) and photopolymerization process parameters (e.g. optical exposure intensity and duration) are controlled to generate particles with tunable crosslinking density-determined properties including elasticity, diffusivity, and biomolecular display for diverse applications such as drug delivery, tissue engineering cell scaffolds, and single- and multiple- cell therapeutics. Similarly, gradients of crosslinking density-determined properties can be created within single particles through the selection of optical exposure intensity and duration. In addition to conventional spherical shapes, a suite of non-spherical shapes may be generated by manipulating the dimensions of the microfluidic channels and other related physical and process parameters. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/647869 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1635 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/14 (20130101) Original (OR) Class B01J 13/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642849 | Varanasi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas); The Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); The Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Venu G. Varanasi (Dallas, Texas); Azhar Ilyas (Arlington, Texas); Philip Roger Kramer (Dallas, Texas); Taha Azimaie (Dallas, Texas); Pranesh B. Aswath (Grapevine, Texas); Tugba Cebe (Grapevine, Texas) |
| ABSTRACT | Bio-Inks and methods of using compositions comprising the bio-Inks are disclosed. 3-D tissue repair and regeneration through precise and specific formation of biodegradable tissue scaffolds in a tissue site using the bio-inks are also provided. Specific methylacrylated gelatin hydrogels (MAC) and methacrylated chitosan (MACh) preparations formulated with sucrose, a silicate-containing component (such as laponite), and/or a cross-linking agent (such as a photo-initiator or chemical initiator), as well as powdered preparations of these, are also disclosed. Kits containing these preparations are provided for point-of-care tissue repair in vivo. Superior, more complete (up to 99.85% tissue regeneration within 4 weeks applied in situ), and rapid in situ tissue repair and bone formation are also demonstrated. |
| FILED | Tuesday, July 30, 2019 |
| APPL NO | 16/526697 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/722 (20130101) A61K 33/00 (20130101) A61K 38/39 (20130101) A61K 41/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 2005/0661 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/307 (20170801) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/046 (20130101) B29K 2995/0056 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643388 | Sheppard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); ShangPharma Innovation Inc. (South San Francisco, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); ShangPharma Innovation Inc. (South San Francisco, California) |
| INVENTOR(S) | Dean Sheppard (Oakland, California); William F. DeGrado (San Francisco, California); Aparna Sundaram (San Francisco, California); Hyunil Jo (Lafayette, California); Richard Beresis (San Francisco, California); Marc Adler (Orinda, California) |
| ABSTRACT | Disclosed herein, inter alia, are inhibitors of alpha 2 beta 1 integrin and methods of using the same. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/246014 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) Acyclic or Carbocyclic Compounds C07C 275/24 (20130101) C07C 275/26 (20130101) Original (OR) Class Heterocyclic Compounds C07D 205/04 (20130101) C07D 213/73 (20130101) C07D 217/02 (20130101) C07D 217/06 (20130101) C07D 239/84 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643393 | Arnaout |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | M. Amin Arnaout (Chestnut Hill, Massachusetts) |
| ABSTRACT | The present application relates to compounds which are integrin antagonists. Methods of preparing the integrin antagonists and methods of treating diseases and disorders associated with abnormal levels and/or expression of one or more integrins are also provided. |
| FILED | Thursday, August 08, 2019 |
| APPL NO | 17/266336 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/04 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Heterocyclic Compounds C07D 211/22 (20130101) Original (OR) Class Peptides C07K 14/70546 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643394 | Mallipattu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); Icahn School of Medicine at Mount Sinai (New York, New York); The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Sandeep Mallipattu (St. James, New York); Bhaskar Das (West Nyack, New York) |
| ABSTRACT | The present disclosure is concerned with small molecule modulators of KLF15 signaling useful for treating various disorders such as, for example, kidney disease (e.g., chronic kidney disease), heart disease, obesity, or a neurodegenerative disorder (e.g., amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, traumatic brain injury, vascular dementia, Huntington's disease, mental retardation, and attention deficit and hyperactivity disorder (ADHD)). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244762 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) Acyclic or Carbocyclic Compounds C07C 321/20 (20130101) Heterocyclic Compounds C07D 213/74 (20130101) C07D 213/85 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643444 | Buehler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Markus J. Buehler (Boxford, Massachusetts); David L. Kaplan (Concord, Massachusetts); Shengjie Ling (Allston, Massachusetts); Kai Jin (Cambridge, Massachusetts) |
| ABSTRACT | The present invention, in some aspects, provides compositions including a solution comprising a plurality of exfoliated silk microfibrils and/or exfoliated silk nanofibrils, wherein the micro- or nano-fibrils are characterized as having a substantially nematic structure, as well as methods for making and using the same. |
| FILED | Friday, March 31, 2017 |
| APPL NO | 16/098954 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Separation B01D 61/145 (20130101) B01D 71/74 (20130101) Peptides C07K 14/43586 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0656 (20130101) Mechanical Treatment of Natural Fibrous or Filamentary Material to Obtain Fibres of Filaments, e.g for Spinning D01B 7/00 (20130101) Chemical Treatment of Natural Filamentary or Fibrous Material to Obtain Filaments or Fibres for Spinning; Carbonising Rags to Recover Animal Fibres D01C 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643450 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Lai-Xi Wang (Ellicott City, Maryland); Wei Huang (Shanghai, China PRC) |
| ABSTRACT | The present invention provides for recombinant Endo-S mutants that exhibit reduced hydrolysis activity and increased transglycosylation activity for the synthesis of glycoproteins wherein a desired sialylated oxazoline or synthetic oligosaccharide oxazoline is added to a core fucosylated or nonfucosylated GlcNAc-protein acceptor. Such recombinant Endo-S mutants are useful for efficient glycosylation remodeling of IgG1-Fc domain to provide different antibody glycoforms carrying structurally well-defined Fc N-glycans. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097534 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6849 (20170801) A61K 47/6867 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) A61P 35/00 (20180101) Peptides C07K 14/473 (20130101) Original (OR) Class C07K 14/4725 (20130101) C07K 16/00 (20130101) C07K 16/18 (20130101) C07K 16/2809 (20130101) C07K 16/2887 (20130101) C07K 2317/10 (20130101) C07K 2317/14 (20130101) C07K 2317/41 (20130101) C07K 2317/52 (20130101) C07K 2317/72 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 1/205 (20210501) C12N 9/2402 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/46 (20210501) Enzymes C12Y 302/01096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643455 | Achkar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York) |
| INVENTOR(S) | Jacqueline M. Achkar (Brooklyn, New York); Jonathan Lai (Dobbs Ferry, New York); Elise Ishida (Aiea, Hawaii); Daniel Hofmann (Moembris, Germany); Tingting Chen (Bronx, New York) |
| ABSTRACT | Provided are high affinity Mycobacterium tuberculosis capsule-specific antibodies and fragments thereof, as well as methods of use and devices employing such antibodies and/or fragments. |
| FILED | Tuesday, December 15, 2020 |
| APPL NO | 17/247532 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1289 (20130101) Original (OR) Class C07K 2317/56 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5302 (20130101) G01N 33/5695 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643462 | Diaz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Luis Diaz (Ellicot City, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Dung Le (Lutherville, Maryland); Drew M. Pardoll (Brookville, Maryland); Suzanne L. Topalian (Brookville, Maryland) |
| ABSTRACT | Blockade of immune checkpoints such as cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed death-1 (PD-1) shows promise in patients with cancer. Inhibitory antibodies directed at these receptors have been shown to break immune tolerance and promote anti-tumor immunity. These agents work particularly well in patients with a certain category of tumor. Such tumors may be particularly susceptible to treatment because of the multitude of neoantigens which they produce. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 17/354653 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/55 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) C07K 16/40 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/00 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 113/11052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643636 | Shusta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Eric V. Shusta (Madison, Wisconsin); Sean P. Palecek (Verona, Wisconsin); Matthew Stebbins (Madison, Wisconsin) |
| ABSTRACT | A population of brain pericyte-like cells, wherein the cells express pericyte markers but do not express ACTA2 and wherein the cells are generated from hPSCs, is disclosed herein. |
| FILED | Wednesday, July 10, 2019 |
| APPL NO | 16/507586 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0618 (20130101) Original (OR) Class C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643652 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Andrew Vito Anzalone (Cambridge, Massachusetts); James William Nelson (Cambridge, Massachusetts) |
| ABSTRACT | Compositions and methods are provided herein for conducting prime editing of a target DNA molecule (e.g., a genome) that enables the incorporation of a nucleotide change and/or targeted mutagenesis. The compositions include fusion proteins comprising nucleic acid programmable DNA binding proteins (napDNAbp) and a polymerase (e.g., reverse transcriptase), which is guided to a specific DNA sequence by a modified guide RNA, named an PEgRNA. The PEgRNA has been altered (relative to a standard guide RNA) to comprise an extended portion that provides a DNA synthesis template sequence which encodes a single strand DNA flap which is synthesized by the polymerase of the fusion protein and which becomes incorporated into the target DNA molecule. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/219635 |
| ART UNIT | 1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/3519 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643659 | Marcucci et al. |
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| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Guido Marcucci (Duarte, California); Ya-Huei Kuo (Duarte, California); Si-ping Han (Duarte, California); Lisa Scherer (Duarte, California); William A. Goddard, III (Pasadena, California); John Rossi (Duarte, California) |
| ABSTRACT | Disclosed herein are conditional siRNAs activatable by CBFβ-MYH11 oncogenic gene and use thereof for treating conditions such as acute myeloid leukemia (AML). The conditional siRNAs target MCL-1 or HDAC8. |
| FILED | Monday, February 10, 2020 |
| APPL NO | 16/786793 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/3519 (20130101) C12N 2320/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643662 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Lily Yang (Atlanta, Georgia); Xiangxue Guo (Lilburn, Georgia) |
| ABSTRACT | This disclosure relates to targeted protease compositions and uses related thereto. In certain embodiments, the disclosure relates to nanoparticles wherein a targeting molecule is linked to the nanoparticle and wherein a catalytic domain of a protease is linked to the nanoparticle. In certain embodiments, the targeting molecule and the catalytic domain are within a single polypeptide sequence. In certain embodiments, the targeting molecule binds a molecule more highly expressed on cancer cells then non-cancerous cells, and the nanoparticles disclosed herein are used for the treatment of cancer by further attaching an anti-cancer agent to the nanoparticle or incorporating an anticancer agent within the nanoparticle. |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/436055 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) A61K 49/0056 (20130101) A61K 49/0065 (20130101) Peptides C07K 2319/01 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) C12N 15/63 (20130101) Original (OR) Class C12N 2810/00 (20130101) Enzymes C12Y 304/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643686 | Salk et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/392193 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644437 | Xie et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Ping Xie (Needham, Massachusetts); Charles M. Lieber (Lexington, Massachusetts) |
| ABSTRACT | There is provided a nanopore sensor including cis and trans fluidic reservoirs. A nanopore is provided in a support structure separating the cis and trans reservoirs. The nanopore has an inlet in fluidic connection with the cis fluidic reservoir and an outlet in fluidic connection with the trans fluidic reservoir. The cis fluidic reservoir has a fluidic access resistance, RC, the trans fluidic reservoir has a fluidic access resistance, RT, and the nanopore has a fluidic resistance, RP. RP is of the same order of magnitude as RT and both RP and RT are at least an order of magnitude greater than RC. An electrical transduction element is disposed at a nanopore sensor site that exposes the transduction element to the trans reservoir. An electrical circuit is connected to the electrical transduction element for producing an electrical signal indicative of changes in electrical potential local to the trans reservoir. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346636 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) Original (OR) Class G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644440 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Shigao Chen (Rochester, Minnesota); James F. Greenleaf (Rochester, Minnesota); Armando Manduca (Rochester, Minnesota); Daniel C. Mellema (Rochester, Minnesota); Joshua D. Trzasko (Rochester, Minnesota); Matthew W. Urban (Rochester, Minnesota) |
| ABSTRACT | Methods for processing data acquired using ultrasound elastography, in which shear waves are generated in a subject using continuous vibration of the ultrasound transducer, are described. The described methods can effectively separate shear wave signals from signals corresponding to residual motion artifacts associated with vibration of the ultrasound transducer. The systems and methods described here also provide for real-time visualization of shear waves propagating in the subject. |
| FILED | Thursday, August 09, 2018 |
| APPL NO | 16/637349 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/42 (20130101) G01N 29/043 (20130101) Original (OR) Class G01N 29/46 (20130101) G01N 29/348 (20130101) G01N 29/0645 (20130101) G01N 2291/044 (20130101) G01N 2291/106 (20130101) G01N 2291/0422 (20130101) G01N 2291/02475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644466 | Polyak et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kornelia Polyak (Brookline, Massachusetts); Vanessa Almendro (Brookline, Massachusetts); Sibgat Choudhury (Chestnut Hill, Massachusetts) |
| ABSTRACT | Methods for treating, preventing and predicting a subject's risk of developing breast cancer are provided. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 16/704941 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2333/705 (20130101) G01N 2333/70585 (20130101) G01N 2333/70596 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644467 | Rimm et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | David L. Rimm (Branford, Connecticut); Kurt Schalper (Branford, Connecticut) |
| ABSTRACT | The present disclosure provides a method of treating cancer by immune checkpoint blockade, or selecting patients for treatment with immune checkpoint blockers, by detecting tumors with high levels of T-lymphocytes with low levels of activation and proliferation. In various embodiments the tissue sample may be from a conventional biopsy. In various embodiments the cancer may be non-small cell lung cancer. |
| FILED | Thursday, November 30, 2017 |
| APPL NO | 16/464010 |
| ART UNIT | 1796 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/2818 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57423 (20130101) Original (OR) Class G01N 2333/4739 (20130101) G01N 2333/7051 (20130101) G01N 2333/70514 (20130101) G01N 2333/70517 (20130101) G01N 2333/70589 (20130101) G01N 2333/96436 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644520 | Gilbo et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Yekaterina K. Gilbo (Charlottesville, Virginia); Helen L. Sporkin (Charlottesville, Virginia); Samuel W. Fielden (Lewisburg, Pennsylvania); John P. Mugler, III (Charlottesville, Virginia); Grady W. Miller, IV (Charlottesville, Virginia); Steven P. Allen (Charlottesville, Virginia); Craig H. Meyer (Charlottesville, Virginia) |
| ABSTRACT | Described herein are systems, methods, and computer-readable medium for magnetic resonance (MR) based thermometry. In one aspect, in accordance with one embodiment, a method for magnetic resonance based thermometry includes: acquiring, by a variable flip-angle T1 mapping sequence, MR data in an area of interest of a subject that is heated by the application of focused ultrasound (FUS) to the brain of the subject, where the MR data includes T1 values over time, and where the acquisition of the MR data includes applying an accelerated three-dimensional ultra-short spiral acquisition sequence with a nonselective excitation pulse; and determining, based at least in part on a mathematical relationship established by T1 mapping thermometry, a temperature change in the area of interest over time, and where the temperature change is caused at least in part by a change in the applied FUS. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144319 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/561 (20130101) G01R 33/3804 (20130101) G01R 33/4814 (20130101) Original (OR) Class G01R 33/4816 (20130101) G01R 33/4818 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644656 | Glaser et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Adam K. Glaser (Seattle, Washington); Jonathan T. C. Liu (Seattle, Washington) |
| ABSTRACT | Apparatuses, systems, and methods for an open-top light-sheet (OTLS) microscope which includes an illumination objective and a collection objective which have optical axes which are non-orthogonal to each other. The optical axis of the collection objective may be orthogonal to a plane of the sample holder. The illumination and collection objective may be located below the sample holder. The OTLS microscope may optionally include a second collection objective which has an optical axis orthogonal to the optical axis of the illumination objective. The illumination objective may be an air objective, and the collection objective may be an immersion objective. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737736 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/06 (20130101) Original (OR) Class G02B 21/33 (20130101) G02B 21/361 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645753 | Madabhushi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The Cleveland Clinic Foundation (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Catherine Jayapandian (Strongsville, Ohio); Yijiang Chen (Cleveland, Ohio); Andrew Janowczyk (East Meadow, New York); John Sedor (Shaker Heights, Ohio); Laura Barisoni (Durham, North Carolina) |
| ABSTRACT | Embodiments discussed herein facilitate segmentation of histological primitives from stained histology of renal biopsies via deep learning and/or training deep learning model(s) to perform such segmentation. One example embodiment is configured to access a first histological image of a renal biopsy comprising a first type of histological primitives, wherein the first histological image is stained with a first type of stain; provide the first histological image to a first deep learning model trained based on the first type of histological primitive and the first type of stain; and receive a first output image from the first deep learning model, wherein the first type of histological primitives is segmented in the first output image. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/032617 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 3/0006 (20130101) G06T 7/11 (20170101) G06T 7/0014 (20130101) Original (OR) Class G06T 11/001 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30084 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646099 | Staudt et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); British Columbia Cancer Agency Branch (Vancouver, Canada); Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Julius-Maximilians-University of Würzburg (Würzburg, Germany); Board of Regents of the University of Nebraska (Lincoln, Nebraska); Oslo University Hospital HF (Oslo, Norway); Hospital Clinic de Barcelona (Barcelona, Spain); Universitat de Barcelona (Barcelona, Spain); Institut D'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS) (Barcelona, Spain); Robert Bosch Gesellschaft fuer medizinische Forschung mbH (Stuttgart, Germany); Oregon Health and Science University (Portland, Oregon); City of Hope (Duarte, California); The Cleveland Clinic Foundation (Cleveland, Ohio) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); British Columbia Cancer Agency (Vancouver, Canada); Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Julius-Maximilians-University of Würzburg (Würuzburg, Germany); Boatd of Regents of the University of Nebraska (Lincoln, Nebraska); Oslo University Hospital HF (Oslo, Norway); Hospital Clinic de Barcelona (Barcelona, Spain); Universitat de Barceloa (Barcelona, Spain); Institut D'Investigacions Biomédiques Pi I Sunyer (IDIBAPS) (Barcelona, Spain); Robert Bosch Gesellschaft feuer medizinische Forshung mbH (Stuttgart, Germany); Oregon Health and Science University (Portland, Oregon); City of Hope (Duarte, California); The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Louis M. Staudt (Bethesda, Maryland); Christian Steidl (North Vancouver, Canada); Anja Mottok (Ulm, Germany); George W. Wright (Rockville, Maryland); David William Scott (Vancouver, Canada); Lisa M. Rimsza (Scottsdale, Arizona); Andreas Rosenwald (Würzburg, Germany); Randy Gascoyne (North Vancouver, Canada); Timothy Greiner (Council Bluffs, Iowa); Dennis Weisenburger (Glendora, California); Erlend B. Smeland (Oslo, Norway); Jan Delabie (Toronto, Canada); Elias Campo Guerri (Barcelona, Spain); German Ott (Bitighein-Bissingen, Germany); Rita Braziel (West Linn, Oregon); Elaine S. Jaffe (Great Falls, Virginia); Kai Fu (Omaha, Nebraska); Wing C. Chan (Pasadena, California); Joo Song (Duarte, California); James R. Cook (Shaker Heights, Ohio) |
| ABSTRACT | In embodiments of the invention, the invention provides a method for distinguishing between lymphoma types based on gene expression measurements. In embodiments, the invention distinguishes between PMBCL and DLBCL based on gene expression signatures, and can further distinguish between DLBCL subtypes. In embodiments of the invention, the distinctions are used in methods of treatment. |
| FILED | Friday, December 13, 2019 |
| APPL NO | 16/713528 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class G16B 25/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11642052 | Beidleman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Beth Beidleman (Holliston, Massachusetts); Mark Buller (Douglas, Massachusetts); Alexander Welles (Brookline, Massachusetts) |
| ABSTRACT | A method of monitoring a subject for the risk of Acute Mountain Sickness (AMS) includes obtaining real-time pulse arterial oxygen saturation (SpO2) measurements from the subject. The SpO2 measurements are transformed into a novel metric known as Accumulated Hypoxic Debt (AHD). The AHD metric is used as the independent variable in a longitudinal generalized linear mixed model to calculate the probability D that the subject is at risk of AMS. Based on the probability D, appropriate courses of action may be communicated to the subject via the output device of a wearable or portable monitor. |
| FILED | Saturday, December 08, 2018 |
| APPL NO | 16/628158 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/02 (20130101) A61B 5/08 (20130101) A61B 5/11 (20130101) A61B 5/22 (20130101) A61B 5/4023 (20130101) A61B 5/7275 (20130101) A61B 5/14551 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642069 | Bergold et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Peter John Bergold (Brooklyn, New York); William Winzer Lytton (Scarsdale, New York); Joshua Michael Skolnick (Far Rockaway, New York) |
| ABSTRACT | A stimulus is displayed in a visual field on a stimulus side (e.g., right or left) of a subject. An input is received from an input side of the subject. Where the input side is contralateral to the first stimulus side, a crossed reaction time is determined as a span of time between displaying the stimulus and receiving the input. Where the input side is ipsilateral to the stimulus side, an uncrossed reaction time is determined as a span of time between displaying the stimulus and receiving the input. A crossed-uncrossed difference time can be determined as a difference between the crossed reaction time and the uncrossed reaction time. The crossed reaction time, the uncrossed reaction time, and/or the crossed-uncrossed difference time can be used to determine a severity of Traumatic Brain Injury of the subject. |
| FILED | Friday, June 03, 2016 |
| APPL NO | 15/579559 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/162 (20130101) A61B 5/163 (20170801) A61B 5/4064 (20130101) Original (OR) Class A61B 2505/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642232 | McDonnall et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ripple, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | Ripple LLC (Salt Lake City, Utah) |
| INVENTOR(S) | Daniel Allen McDonnall (Salt Lake City, Utah); Scott Darold Hiatt (South Jordan, Utah); Brian Scott Crofts (Salt Lake City, Utah); Christopher Farand Smith (North Salt Lake, Utah); Andrew Miller Wilder (Salt Lake City, Utah) |
| ABSTRACT | Disclosed herein are systems and methods for sensor systems. In one embodiment, a system may include an implantable component and an external component. The implantable component may comprise a housing and an electrode array configured to receive a plurality of biopotential signals. The housing may comprise a wireless power receiver and a wireless data transmitter to transmit representations of the biopotential signals. The external component may comprise a wireless data receiver configured to receive the plurality of digital representations of the biopotential signals and a wireless power transmitter configured to provide power to the internal component. A shielding component may separate the wireless power transmitter from the wireless data receiver. An interface may be configured to communicate with a prosthesis and configured to cause the prosthesis to implement a voluntary motion based on the plurality of digital presentations of the biopotential signals. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 16/869248 |
| ART UNIT | 2683 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0017 (20130101) A61B 5/0031 (20130101) A61B 5/296 (20210101) A61B 5/389 (20210101) A61B 2560/0214 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Original (OR) Class A61F 2002/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642313 | DeSimone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Belmont, Massachusetts); Benjamin W. Maynor (Durham, North Carolina); Larken E. Euliss (Augoura Hills, California); Ginger Denison Rothrock (Durham, North Carolina); Ansley E. Dennis (Augusta, Georgia); Edward T. Samulski (Chapel Hill, North Carolina); R. Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
| FILED | Wednesday, November 11, 2020 |
| APPL NO | 17/095301 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 9/0097 (20130101) A61K 9/5138 (20130101) A61K 9/5153 (20130101) A61K 9/5192 (20130101) A61K 47/34 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/0085 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0004 (20130101) H01L 51/0021 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/24273 (20150115) Y10T 428/24479 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642407 | Ricke |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Darrell O. Ricke (Winchester, Massachusetts) |
| ABSTRACT | Provided herein are universal prophylactic compositions for preventing infection with influenza viruses by directing the immune response to highly conserved regions of the virus. Also provided are universal therapeutic compositions for treating influenza infection by targeting the highly conserved regions. Methods for using the prophylactic and therapeutic compositions are also provided. |
| FILED | Friday, February 26, 2021 |
| APPL NO | 17/186851 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/16 (20130101) A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642694 | Pringle, IV et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | John Walter Pringle, IV (Torrance, California); Angelica Davancens (Reseda, California); Ryan Vutha Touch (Irvine, California); Dehwei Oliver Hsu (Cypress, California) |
| ABSTRACT | A robot end effector for dispensing an extrudable substance comprises a chassis and cartridge bays, attached to the chassis and each shaped to receive a corresponding one of two-part cartridges. Robot end effector also comprises a dispensing valve, attached to the chassis and comprising a valve inlet and a valve outlet, in selective fluidic communication with the valve inlet. Robot end effector further comprises a manifold, comprising a manifold outlet and manifold inlets. The manifold outlet is in fluidic communication with the valve inlet. Robot end effector additionally comprises a plunger assembly, comprising pairs of plungers. Plunger assembly is arranged to concurrently extrude contents of the two-part cartridges through the cartridge outlets when the two-part cartridges are received by the cartridge bays. Robot end effector also comprises a non-rotating linear pneumatic actuator, configured to selectively move the plunger assembly relative to the chassis. |
| FILED | Friday, May 22, 2020 |
| APPL NO | 16/882421 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Apparatus for Applying Fluent Materials to Surfaces, in General B05C 5/00 (20130101) B05C 5/0216 (20130101) B05C 11/1036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643169 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the USA represented by the Sec. of the Navy (Washington, District of Columbia); Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Xaiobo Tan (Okemos, Michigan); Thassyo Da Silva Pinto (East Lansing, Michigan); Demetris Coleman (East Lansing, Michigan); Weilin Hou (Slidell, Louisiana); Silvia Matt (Carriere, Mississippi); Sergio Restaino (Alexandria, Virginia); Freddie Santiago (Fort Washington, Maryland); Hongyang Shi (East Lansing, Michigan) |
| ABSTRACT | An apparatus including a controllable fluid-contacting surface is provided. In another aspect, the present apparatus includes a flexible membrane and multiple actuators each having an output shaft or activation member coupled to a water-contacting membrane, with the shafts extending in a direction offset from the nominal outer surface of the membrane. A further aspect of the present apparatus includes an underwater vessel including a propulsion source, a flexible membrane having a water-contacting outer surface and an electronic controller including programmable software for actuating the actuators. |
| FILED | Tuesday, October 29, 2019 |
| APPL NO | 16/667089 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 1/32 (20130101) Original (OR) Class B63B 1/36 (20130101) B63B 79/15 (20200101) B63B 79/40 (20200101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/007 (20130101) F15D 1/12 (20130101) Dynamo-electric Machines H02K 7/14 (20130101) H02K 21/24 (20130101) H02K 33/16 (20130101) H02K 35/02 (20130101) H02K 41/031 (20130101) Selecting H04Q 3/545 (20130101) H04Q 3/54575 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643177 | Ripplinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battle Sight Technologies, LLC (Dayton, Ohio) |
| ASSIGNEE(S) | Battle Sight Technologies, LLC (Dayton, Ohio) |
| INVENTOR(S) | Nicholas R. Ripplinger (Springboro, Ohio); Christopher J. Vogt (Cincinnati, Ohio) |
| ABSTRACT | An apparatus that facilitates search and rescue, for example, in open water. The apparatus comprises a substrate with a particular geometry and a perimeter. The apparatus further comprises a cover positioned atop the substrate with the cover also having a particular geometry and perimeter, which correspond to the geometry and perimeter of the substrate. An air-tight seal seals the substrate perimeter to the cover perimeter and creates a sealed internal region. A breakable vessel holding an activator is located in the sealed internal region, along with illuminable dyes that are also located in the sealed internal region. When the breakable vessel is broken, the activator reacts with the illuminable dyes and illuminates the illuminable dyes. |
| FILED | Thursday, March 17, 2022 |
| APPL NO | 17/697335 |
| ART UNIT | 3617 — Fluid Handling and Dispensing |
| CURRENT CPC | Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 9/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643209 | Kiser |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Brett Kiser (Honolulu, Hawaii) |
| ABSTRACT | An aircraft loading system is configured to tether equipment within an aircraft. The loading system has a wedge shaped bracket that has a front plate joined to two side plates and a bottom plate. A middle plate is parallel to the front plate and joins the two side plates. A front opening is arranged through the bottom plate between the front plate and the middle plate. The front opening is configured to accommodate an attachment ring. The attachment ring is used to tether the equipment within the aircraft. |
| FILED | Monday, September 28, 2020 |
| APPL NO | 17/034332 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects B60P 7/0807 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 9/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643215 | White et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Christopher James White (Yeovil, United Kingdom); Jan Ludvik (Jesenice, Czech Republic) |
| ABSTRACT | A system includes a concentration sensor, a flow sensor, and a controller. The concentration sensor is configured to measure a concentration of a contaminant in a cabin of an aircraft. The flow sensor is configured to measure a flow rate of air into the cabin. The controller is configured to determine whether a concentration measurement of the contaminant in the cabin exceeds a first concentration threshold. The controller is configured to, in response to determining that the concentration measurement does not exceed the first concentration threshold, control the flow rate of air into the cabin based on a flow rate setpoint. The controller is configured to, in response to determining that the concentration measurement exceeds the first concentration threshold, control the flow rate of air into the cabin based on a flow rate setpoint and a correction factor that is based on a flow sensor tolerance. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/897076 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 13/04 (20130101) B64D 13/06 (20130101) Original (OR) Class B64D 13/08 (20130101) B64D 2013/0603 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 9/001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643225 | Helvajian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Henry Helvajian (Pasadena, California); Randy Villahermosa (Pasadena, California) |
| ABSTRACT | Cell-based systems may interlock in a reconfigurable configuration to support a mission. Space systems, for example, of a relatively large size may be assembled using an ensemble of individual “cells”, which are individual space vehicles. The cells may be held together via magnets, electromagnets, mechanical interlocks, etc. The topology or shape of the joined cells may be altered by cells hopping, rotating, or “rolling” along the joint ensemble. The cells may be multifunctional, mass producible units. Rotation of cell faces, or of components within cells, may change the functionality of the cell. The cell maybe collapsible for stowage or during launch. |
| FILED | Friday, July 21, 2017 |
| APPL NO | 15/655972 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/244 (20190501) B64G 1/283 (20130101) Original (OR) Class B64G 1/443 (20130101) B64G 1/645 (20130101) B64G 1/646 (20130101) B64G 1/1085 (20130101) B64G 2001/1092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643406 | Palmese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania); The Government of the United States of America, as represented by The Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania); The Government of the United States of America, as represented by The Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Giuseppe R. Palmese (Hainesport, New Jersey); Santosh K. Yadav (Geneva, Ohio); John J. LaScala (Wilimington, Delaware) |
| ABSTRACT | Benzoxazine compounds, methods of making them, polymers made therefrom and methods of polymerizing the benzoxazines. These renewable benzoxazine monomers and polymers that utilize the variety of building blocks found in renewable plant biomass, demonstrate excellent processability and large temperature windows for processing of resin systems. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/637551 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 307/52 (20130101) C07D 413/06 (20130101) Original (OR) Class C07D 413/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/024 (20130101) C08G 73/0273 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643443 | Joshi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Neel Satish Joshi (Somerville, Massachusetts); Noémie-Manuelle Dorval Courchesne (Cambridge, Massachusetts) |
| ABSTRACT | Methods of making engineered protein-based materials, nanofibers, and biofilms from bacterial amyloid-based structures that are capable of mediating long-range electron transport are provided. |
| FILED | Friday, November 18, 2016 |
| APPL NO | 15/777070 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 14/195 (20130101) C07K 14/245 (20130101) Original (OR) Class C07K 14/395 (20130101) C07K 14/4711 (20130101) C07K 14/4717 (20130101) C07K 2319/00 (20130101) C07K 2319/20 (20130101) C07K 2319/21 (20130101) C07K 2319/23 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0065 (20130101) C12N 9/2462 (20130101) Enzymes C12Y 111/01007 (20130101) C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643563 | Velev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Orlin D. Velev (Cary, North Carolina); Sangchul Roh (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure relates to compositions and methods for three-dimensional printing. |
| FILED | Thursday, July 13, 2017 |
| APPL NO | 16/317073 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/36 (20130101) C09D 11/38 (20130101) C09D 11/40 (20130101) C09D 11/54 (20130101) C09D 11/102 (20130101) Original (OR) Class C09D 11/322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643636 | Shusta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Eric V. Shusta (Madison, Wisconsin); Sean P. Palecek (Verona, Wisconsin); Matthew Stebbins (Madison, Wisconsin) |
| ABSTRACT | A population of brain pericyte-like cells, wherein the cells express pericyte markers but do not express ACTA2 and wherein the cells are generated from hPSCs, is disclosed herein. |
| FILED | Wednesday, July 10, 2019 |
| APPL NO | 16/507586 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0618 (20130101) Original (OR) Class C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643672 | Unwalla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hoshang Jehangir Unwalla (Miami, Florida); Srinivasan Chinnapaiyan (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTERS (Miami, Florida) |
| INVENTOR(S) | Hoshang Jehangir Unwalla (Miami, Florida); Srinivasan Chinnapaiyan (Miami, Florida) |
| ABSTRACT | The invention pertains to an inducible CRISPR system for controlling expression of a CRISPR complex with an inducible fusion promoter. One embodiment of the invention provides HIV LTR-minimal Drosophila hsp70 fusion promoter that can be used for inducible co-expression of gRNA and Cas9 in HIV-infected cells to target cellular cofactors such as Cyclin T1. A single introduction of such embodiment leads to sustained suppression of HIV replication in stringent, chronically infected HeLa-CD4 cell lines as well as in T-cell lines. In another embodiment, the invention further relates to enhancement of HIV suppression by incorporating cis-acting ribozymes immediately upstream of the gRNA in the inducible CRISPR system construct. The inducible fusion promoter is adaptable for other tissue- or cell-type specific expression of the inducible CRISPR system. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 17/491738 |
| ART UNIT | 1699 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/85 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2740/16041 (20130101) C12N 2830/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643676 | Petillo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Design-Zyme LLC (Lawrence, Kansas) |
| ASSIGNEE(S) | Design-Zyme LLC (Lawrence, Kansas) |
| INVENTOR(S) | Peter Albert Petillo (Lawrence, Kansas); Dwight O'Dell Deay, III (Lawrence, Kansas); Michael Gregory Branden (Lawrence, Kansas) |
| ABSTRACT | The present invention is broadly concerned with new in vitro glycosylation methods that provide rational approaches for producing glycosylated proteins, and the use of glycosylated proteins. In more detail, the present invention comprises methods of glycosylating a starting protein having an amino sidechain with a nucleophilic moiety, comprising the step of reacting the protein with a carbohydrate having an oxazoline moiety on the reducing end thereof, to covalently bond the amino sidechain of the starting protein with the oxazoline moiety, wherein the glycosylated protein substantially retains the structure and function of the starting protein. Target proteins include oxidase, oxidoreductase and dehydrogenase enzymes. The glycosylated proteins advantageously have molecular weights of at least about 7500 Daltons. In a further embodiment, the present invention concerns the use of glycosylated proteins, fabricated by the methods disclosed herein, in the assembly of amperometric biosensors. |
| FILED | Thursday, April 08, 2021 |
| APPL NO | 17/301590 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/006 (20130101) C07K 1/1077 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/0006 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643968 | Bacon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Bruce Bennett Bacon (Euless, Texas); Kristine Joyce Lazo (Dallas, Texas); Shawn Patrick Leonard, Jr. (Fort Worth, Texas) |
| ABSTRACT | An air intake system for an aircraft, which is switchable between a performance mode and a filtered mode, includes a duct forming filtered air inlet slits. The air intake system also includes interconnected gills adjacent to the filtered air inlet slits. The gills are movable between various gill positions including a closed position substantially covering the filtered air inlet slits and an open position substantially exposing the filtered air inlet slits. The air intake system also includes an actuator configured to move the gills into the closed position in the performance mode and the open position in the filtered mode. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/313267 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/02 (20130101) B64D 2033/0253 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/055 (20130101) F02C 7/057 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/329 (20130101) F05D 2240/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644046 | Cottrell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| INVENTOR(S) | Daniel Cottrell (Manassas, Virginia); Randall Tatman (Manassas, Virginia); Steven Petullo (Bristow, Virginia) |
| ABSTRACT | A fan blade comprising a blade body spanning from a blade root to a blade tip in a longitudinal direction and a fluid passageway formed within the blade body and extending from the blade root to the blade tip. The blade body spanning from a leading edge to a trailing edge in a lateral direction. The fluid passageway allowing fluid to flow out of the blade. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 15/863210 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 11/16 (20130101) B64C 11/18 (20130101) B64C 11/24 (20130101) B64C 11/26 (20130101) B64C 11/30 (20130101) B64C 29/0033 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/02 (20130101) Non-positive-displacement Pumps F04D 29/36 (20130101) F04D 29/164 (20130101) F04D 29/324 (20130101) F04D 29/388 (20130101) Original (OR) Class F04D 29/522 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644278 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Dean Reed (Titusville, Florida); Devyn Dodge (Orlando, Florida); Troyle Thomas (Winter Springs, Florida) |
| ABSTRACT | A device can include one or more sensors configured to output sensor data, and a trigger detection module configured to receive the sensor data from the one or more sensors and to determine whether a trigger event has occurred. The trigger detection module can be configured to output a trigger detection signal when the trigger event is detected. The trigger detection signal can be configured to be used by an augmented reality or virtual reality system to cause an augmented reality or virtual reality event. |
| FILED | Tuesday, December 29, 2020 |
| APPL NO | 17/137287 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 33/02 (20130101) Weapon Sights; Aiming F41G 3/32 (20130101) F41G 3/2633 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 19/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644288 | Schuh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Christopher A. Schuh (Wayland, Massachusetts); Zachary Copoulos Cordero (Cambridge, Massachusetts); Mansoo Park (Boston, Massachusetts) |
| ABSTRACT | Nanocrystalline alloy penetrators and related methods are generally provided. In some embodiments, a munition comprises a nanocrystalline alloy penetrator. In certain embodiments, the nanocrystalline alloy has particular properties (e.g., grain size, grain isotropy, mechanical properties) such that the penetrator acts as a rigid body kinetic penetrator. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/268096 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Alloys C22C 27/04 (20130101) C22C 27/06 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/18 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/06 (20130101) Original (OR) Class F42B 12/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644291 | Hansen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Karman Holdings, LLC (Huntington Beach, California) |
| ASSIGNEE(S) | Karman Holdings, LLC (Huntington Beach, California) |
| INVENTOR(S) | Stephanie J. Hansen (Woodinville, Washington); Keith Krasnowski (Lynnwood, Washington); Peter J. Golden (Seattle, Washington); Michael Knollmeyer (Kirkland, Washington); Minh Button (Mountlake Terrace, Washington); Morgan Condit (Lake Forest Park, Washington); Joel Hoksbergen (Bow, Washington); Andrew Lindo (Mount Vernon, Washington) |
| ABSTRACT | Multistage thermal trigger devices disclosed herein may include a first stage and a second stage, wherein the first stage activates at a first temperature, and wherein the second stage activates at a second temperature. The first stage activates an arming assembly so that the second stage is armed. The second stage may then activate the output of the multistage thermal trigger device, via the arming assembly, when the second temperature is reached. An autoignition material (AIM) capsule is also disclosed herein. The AIM capsule may be deployed in connection with the disclosed multistage thermal trigger devices. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/895615 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/36 (20130101) F42C 19/08 (20130101) F42C 19/0803 (20130101) F42C 19/0815 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644313 | Wen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Haoran Wen (Atlanta, Georgia); Farrokh Ayazi (Atlanta, Georgia) |
| ABSTRACT | A microelectromechanical resonator includes a resonator member suspended over a surface of a substrate by at least one anchor that is connected to the substrate. The resonator member includes outer and inner frames that are concentrically arranged and mechanically coupled by support structures extending therebetween. Related apparatus and gyroscopes are also discussed. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 16/644389 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/02 (20130101) B81B 2201/0242 (20130101) B81B 2201/0271 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5684 (20130101) Original (OR) Class G01C 19/5698 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644466 | Polyak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kornelia Polyak (Brookline, Massachusetts); Vanessa Almendro (Brookline, Massachusetts); Sibgat Choudhury (Chestnut Hill, Massachusetts) |
| ABSTRACT | Methods for treating, preventing and predicting a subject's risk of developing breast cancer are provided. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 16/704941 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) Original (OR) Class G01N 2333/47 (20130101) G01N 2333/705 (20130101) G01N 2333/70585 (20130101) G01N 2333/70596 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644578 | Phan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| ASSIGNEE(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| INVENTOR(S) | Huan T. Phan (Cedar Rapids, Iowa); Gary A. McGraw (Cedar Rapids, Iowa); Michael J. Armatys (Cedar Rapids, Iowa) |
| ABSTRACT | A system and for determining precision navigation solutions decorrelates GPS carrier-phase ambiguities derived from multiple-source GPS information via Least-squares AMBiguity Decorrelation Adjustment (LAMBDA) algorithms. The set of decorrelated floating-point ambiguities is used to compute protection levels and the probability of almost fix (PAF), or the probability that the partial almost-fix solution corresponding to the decorrelated ambiguities is within the region of correctly-fixed or low-error almost-fixed ambiguities. While the PAF remains below threshold and the protection levels remain below alert levels, the optimal navigation solution (floating-point, partial almost-fix, or fully fixed) is generated by fixing the decorrelated ambiguities are one at a time in the LAMBDA domain and replacing the appropriate carrier-phase ambiguities with the corresponding fixed ambiguities, reverting to the last solution if PAF reaches the threshold or if protection levels reach the alert levels. |
| FILED | Wednesday, December 29, 2021 |
| APPL NO | 17/564906 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/07 (20130101) G01S 19/15 (20130101) G01S 19/20 (20130101) G01S 19/40 (20130101) G01S 19/41 (20130101) G01S 19/44 (20130101) Original (OR) Class G01S 19/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644656 | Glaser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Adam K. Glaser (Seattle, Washington); Jonathan T. C. Liu (Seattle, Washington) |
| ABSTRACT | Apparatuses, systems, and methods for an open-top light-sheet (OTLS) microscope which includes an illumination objective and a collection objective which have optical axes which are non-orthogonal to each other. The optical axis of the collection objective may be orthogonal to a plane of the sample holder. The illumination and collection objective may be located below the sample holder. The OTLS microscope may optionally include a second collection objective which has an optical axis orthogonal to the optical axis of the illumination objective. The illumination objective may be an air objective, and the collection objective may be an immersion objective. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737736 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/06 (20130101) Original (OR) Class G02B 21/33 (20130101) G02B 21/361 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644682 | O'Toole et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Matthew O'Toole (Pittsburgh, Pennsylvania); Mark Sheinin (Pittsburgh, Pennsylvania); Srinivasa Narasimhan (Pittsburgh, Pennsylvania) |
| ABSTRACT | A novel class of imaging systems that combines diffractive optics with 1D line sensing is disclosed. When light passes through a diffraction grating or prism, it disperses as a function of wavelength. This property is exploited to recover 2D and 3D positions from line images. A detailed image formation model and a learning-based algorithm for 2D position estimation are disclosed. The disclosure includes several extensions of the imaging system to improve the accuracy of the 2D position estimates and to expand the effective field-of-view. The invention is useful for fast passive imaging of sparse light sources, such as streetlamps, headlights at night and LED-based motion capture, and structured light 3D scanning with line illumination and line sensing. |
| FILED | Thursday, February 18, 2021 |
| APPL NO | 17/178855 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/002 (20130101) G01B 11/03 (20130101) Optical Elements, Systems, or Apparatus G02B 5/18 (20130101) G02B 27/0944 (20130101) G02B 27/4233 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644835 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TOYOTA RESEARCH INSTITUTE, INC. (Los Altos, California); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | TOYOTA RESEARCH INSTITUTE, INC. (Los Altos, California); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Mingyu Wang (Stanford, California); Negar Zahedi Mehr (Stanford, California); Adrien David Gaidon (Mountain View, California); Mac Schwager (San Francisco, California) |
| ABSTRACT | A method for risk-aware game-theoretic trajectory planning is described. The method includes modeling an ego vehicle and at least one other vehicle as risk-aware agents in a game-theoretic driving environment. The method also includes ranking upcoming planned trajectories according to a risk-aware cost function of the ego vehicle and a risk-sensitivity of the other vehicle associated with each of the upcoming planned trajectories. The method further includes selecting a vehicle trajectory according to the ranking of the upcoming planned trajectories based on the risk-aware cost function and the risk-sensitivity of the other vehicle associated with each of the upcoming planned trajectories to reach a target destination according to a mission plan. |
| FILED | Wednesday, July 29, 2020 |
| APPL NO | 16/942560 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/16 (20130101) B60W 30/0953 (20130101) B60W 30/0956 (20130101) B60W 30/18163 (20130101) B60W 40/09 (20130101) B60W 60/0011 (20200201) B60W 60/0025 (20200201) B60W 2556/65 (20200201) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3453 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) Original (OR) Class G05D 1/0214 (20130101) Wireless Communication Networks H04W 4/40 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645101 | Turner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Assured Information Security, Inc. (Rome, New York) |
| ASSIGNEE(S) | ASSURED INFORMATION SECURITY, INC. (Rome, New York) |
| INVENTOR(S) | Richard Turner (Verona, New York); Joel Upham (Paris, New York) |
| ABSTRACT | Provision of a virtual secure cryptoprocessor (VSC) for a guest virtual machine (VM), part of a first guest, of a hypervisor of a computer system, includes (i) storing guest VM state and VSC state together in an encrypted virtual hard disk drive file, (ii) storing a decryption key in a sealed partition, of a second guest, sealed against a physical secure cryptoprocessor, (iii) based on verifying that a host computing environment of the computer system is in a trusted state and on booting the hypervisor thereon, unsealing the sealed partition of the second guest, the unsealing providing the decryption key, and decrypting the encrypted virtual hard disk drive file using the decryption key, where the decrypting decrypts the stored guest VM state for execution of the guest VM and decrypts the VSC state to provide the VSC for use by the guest VM. |
| FILED | Tuesday, March 31, 2020 |
| APPL NO | 16/835875 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) Original (OR) Class G06F 21/53 (20130101) G06F 21/78 (20130101) G06F 21/575 (20130101) G06F 21/6209 (20130101) G06F 2009/45587 (20130101) G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645222 | Prentice |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | US Gov't as represented by Sec'y of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | David C Prentice (Springboro, Ohio) |
| ABSTRACT | Various embodiments comprise systems, mechanisms, methods and apparatus configured to regenerate or recreate a stream of substantially continuous serial bus data traffic using stored data packet sequences representing captured energy associated with inverting and non-inverting communication lines of a differential transmission line type of serial bus (e.g., RS-422, MIL STD 1553, and the like). |
| FILED | Tuesday, January 11, 2022 |
| APPL NO | 17/572853 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 13/1668 (20130101) G06F 13/4282 (20130101) Original (OR) Class G06F 2213/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645380 | Chittamuru et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Sai Vineel Reddy Chittamuru (Fort Collins, Colorado); Sudeep Pasricha (Fort Collins, Colorado); Ishan Thakkar (Fort Collins, Colorado) |
| ABSTRACT | The exemplified methods and systems provide hardware-circuit-level encryption for inter-core communication of photonic communication devices such as photonic network-on-chip devices. In some embodiments, the hardware-circuit level encryption uses authentication signatures that are based on process variation that inherently occur during the fabrication of the photonic communication device. The hardware level encryption can facilitate high bandwidth on-chip data transfers while preventing hardware-based trojans embedded in components of the photonic communication device such as PNoC devices or preventing external snooping devices from snooping data from the neighboring photonic signal transmission medium in a shared photonic signal transmission medium. In some embodiments, the hardware-circuit-level encryption is used for unicast/multicast traffic. |
| FILED | Friday, June 07, 2019 |
| APPL NO | 16/434420 |
| ART UNIT | 2496 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 15/7825 (20130101) G06F 21/44 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) Wireless Communication Networks H04W 4/06 (20130101) H04W 12/069 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645444 | Scheutz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Matthias J. Scheutz (Boston, Massachusetts); Evan A. Krause (Somerville, Massachusetts) |
| ABSTRACT | An intelligent system, such as an autonomous robot agent, includes systems and methods to learn various aspects about a task in response to instructions received from a human instructor, to apply the instructed knowledge immediately during task performance following the instruction, and to instruct other intelligent systems about the knowledge for performing the task. The learning is accomplished free of training the intelligent system. The instructions from the human instructor may be provided in a natural language format and may include deictic references. The instructions may be received while the intelligent system is online, and may be provided to the intelligent system in one shot, e.g., in a single encounter or transaction with the human instructor. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 16/098785 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/40153 (20130101) Electric Digital Data Processing G06F 16/3344 (20190101) G06F 16/90332 (20190101) G06F 16/90335 (20190101) G06F 40/00 (20200101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645544 | Rostami et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
| INVENTOR(S) | Mohammad Rostami (Los Angeles, California); Soheil Kolouri (Agoura Hills, California); Praveen K. Pilly (West Hills, California) |
| ABSTRACT | Described is a system for continual learning using experience replay. In operation, the system receives a plurality of tasks sequentially, from which a current task is fed to an encoder. The current task has data points associated with the current task. The encoder then maps the data points into an embedding space, which reflects the data points as discriminative features. A decoder then generates pseudo-data points from the discriminative features, which are provided back to the encoder. The discriminative features are updated in the embedding space based on the pseudo-data points. The encoder then learns (updates) a classification of a new task by matching the new task with the discriminative features in the embedding space. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875852 |
| ART UNIT | 2652 — Videophones and Telephonic Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/088 (20130101) Original (OR) Class G06N 3/0454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646201 | Tassev et al. |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Vladimir Tassev (Beavercreek, Ohio); Shivashankar Vangala (Mason, Ohio); David H Tomich (New Carlisle, Ohio) |
| ABSTRACT | A method for preparation of orientation-patterned (OP) templates comprising the steps of: depositing a first layer of a first material on a common substrate by a far-from-equilibrium process; and depositing a first layer of a second material on the first layer of the first material by a close-to-equilibrium process, wherein a first assembly is formed. The first material and the second material may be the same material or different materials. The substrate material may be Al2O3 (sapphire), silicon (Si), germanium (Ge), GaAs, GaP, GaSb, InAs, InP, CdTe, CdS, CdSe, or GaSe. The first material deposited on the common substrate may be one or more electronic or optical binary materials from the group consisting of AlN, GaN, GaP, InP, GaAs, InAs, AlAs, ZnSe, GaSe, ZnTe, CdTe, HgTe, GaSb, SiC, CdS, CdSe, or their ternaries or quaternaries. The far-from-equilibrium process is one of MOCVD and MBE, and the close-to-equilibrium process is HVPE. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346642 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/02502 (20130101) H01L 21/02516 (20130101) Original (OR) Class H01L 21/02609 (20130101) H01L 21/02667 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646395 | Liao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Yitao Liao (Redwood City, California); Theodore D. Moustakas (Dover, Massachusetts) |
| ABSTRACT | A method of growing an AlGaN semiconductor material utilizes an excess of Ga above the stoichiometric amount typically used. The excess Ga results in the formation of band structure potential fluctuations that improve the efficiency of radiative recombination and increase light generation of optoelectronic devices, in particular ultraviolet light emitting diodes, made using the method. Several improvements in UV LED design and performance are also provided for use together with the excess Ga growth method. Devices made with the method can be used for water purification, surface sterilization, communications, and data storage and retrieval. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/723966 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0237 (20130101) H01L 21/0242 (20130101) H01L 21/0254 (20130101) H01L 21/0259 (20130101) H01L 21/02458 (20130101) H01L 21/02507 (20130101) H01L 21/02573 (20130101) H01L 21/02625 (20130101) H01L 33/06 (20130101) H01L 33/007 (20130101) H01L 33/025 (20130101) H01L 33/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646795 | Pascoguin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Bienvenido Melvin L. Pascoguin (San Diego, California); Brittany Lynn (San Diego, California) |
| ABSTRACT | A system for electromagnetic communication with a vortex beam concurrently conveys multiple topological charges of orbital angular momentum. The system includes a source, at least one vortex-sensing diffraction grating, and an array of photodetectors. The source generates the vortex beam concurrently conveying a respective number of selected topological charges during each of the time intervals. The selected topological charges for each time interval are selected from a set of available topological charges. The selected topological charges for each time interval encode a symbol of data. The vortex-sensing diffraction grating combines a vortex phase pattern and a linear phase pattern. The vortex sensing diffraction grating produces a diffraction pattern from diffracting the vortex beam received from the source. The array of photodetectors detects portions of the diffraction pattern and from the detected portions recovers the selected topological charges encoding the symbol of each time interval. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 17/535281 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/4233 (20130101) Transmission H04B 10/27 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11647041 | Njilla et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Rome, New York) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Rome, New York) |
| INVENTOR(S) | Laurent Y Njilla (Liverpool, New York); Celestin Wafo Soh (Ridgeland, Mississippi) |
| ABSTRACT | A system and method enabling enterprises to engage in cyber threat information sharing in a privacy-enhanced fashion. The invention reduces the enterprise's risk to sensitive information leakage by inducing a state in the information it shares such that, when an enterprise's shared data attributes are interdependent, the sensitive features (those to be kept private to the enterprise) are not deducible by another enterprise. This state is accomplished by employing rough set theory to undermine the deductive route to the data's sensitive features. |
| FILED | Thursday, September 19, 2019 |
| APPL NO | 16/575790 |
| ART UNIT | 2419 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/20 (20190101) G06F 16/278 (20190101) G06F 16/2282 (20190101) G06F 21/6254 (20130101) Computer Systems Based on Specific Computational Models G06N 5/01 (20230101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0428 (20130101) H04L 63/1441 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11647673 | Taylor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin J. Taylor (Escondido, California); Teresa H. Emery (San Diego, California) |
| ABSTRACT | An antenna comprising; a substrate; a continuous film of yttrium barium copper oxide (YBCO) disposed on the substrate having first and second regions, wherein the first region has a first oxygen doping level and wherein the second region has a second oxygen doping level that is different from the first oxygen doping level; a nano-scale conductive structure, shaped to resonate at a terahertz (THz) frequency, disposed on a boundary between the first and second regions; and a conductive path electrically connected to the first and second regions and to the conductive structure such that induced current in the structure due to incoming THz radiation heats the boundary thereby creating a thermal gradient, which results in the generation of Seebeck effect voltage. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 17/355005 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Electric solid-state devices not otherwise provided for H10N 10/17 (20230201) Original (OR) Class H10N 10/81 (20230201) H10N 60/20 (20230201) H10N 60/124 (20230201) H10N 60/203 (20230201) H10N 60/0941 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11642074 | Arnold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KNOW BIOLOGICAL, INC. (Milton, Georgia); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Know Biological, Inc. (Milton, Georgia); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Gary Stephen Arnold (Cumming, Georgia); Matthew Wallace Moorman (Albuquerque, New Mexico); Joshua Jonathan Whiting (Albuquerque, New Mexico) |
| ABSTRACT | A method of detecting a seizure includes collecting volatile organic compounds with a collector material of a collector; separating a mixture of the volatile organic compounds into its constituent chemicals with a gas chromatography column; ionizing the constituent chemicals to create ionized chemicals and detecting the ionized chemicals; and analyzing the ionized chemicals to identify seizure-indicative volatile organic compounds. |
| FILED | Wednesday, May 05, 2021 |
| APPL NO | 17/308145 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/443 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/6831 (20130101) A61B 5/6833 (20130101) A61B 5/14546 (20130101) A61B 10/00 (20130101) A61B 2010/0083 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/00 (20130101) G01N 30/20 (20130101) G01N 30/64 (20130101) G01N 30/80 (20130101) G01N 2030/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642665 | Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Mark E. Davis (Pasadena, California); Stephen Kramer Brand (Pasadena, California); Joel E. Schmidt (Utrecht, Netherlands); Michael W. Deem (West University Place, Texas) |
| ABSTRACT | This disclosure describes enantiomerically enriched chiral molecular sieves and methods of making and using the same. In some embodiments, the molecular sieves are silicates or germanosilicates of STW topology. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 17/523485 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/047 (20130101) Original (OR) Class B01J 31/0244 (20130101) B01J 35/002 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/07 (20130101) Acyclic or Carbocyclic Compounds C07C 2529/04 (20130101) Heterocyclic Compounds C07D 233/66 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20075 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642819 | Aitharaju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Venkateshwar R. Aitharaju (Troy, Michigan); William R. Rodgers (Bloomfield Township, Michigan); Selina X. Zhao (Rochester Hills, Michigan); Terrence Wathen (Sterling Heights, Michigan) |
| ABSTRACT | A method of manufacturing a composite component according to various aspects of the present disclosure includes disposing a fiber preform in a mold. The fiber preform includes a first portion having a first edge and a second portion having a second edge. The first edge and the second edge cooperate to at least partially define a gap. One of the first portion or the second portion includes a first ferromagnetic material and the other of the first portion or the second portion includes a first magnetic or magnetizable component. The method further includes closing the gap by generating a magnetic field from the first magnetic or magnetizable component. The method further includes injecting a polymer precursor into the mold. The method further includes forming the composite component by solidifying the polymer precursor to form a polymer. The composite component includes the fiber preform and the polymer. |
| FILED | Monday, January 27, 2020 |
| APPL NO | 16/773516 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 31/008 (20130101) B29C 33/16 (20130101) B29C 33/32 (20130101) B29C 45/14008 (20130101) B29C 45/14065 (20130101) Original (OR) Class B29C 2045/14131 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642841 | Saito et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Tomonori Saito (Knoxville, Tennessee); Amy M. Elliott (Oak Ridge, Tennessee) |
| ABSTRACT | A method for indirect additive manufacturing of an object, the method comprising: (i) separately feeding a powder from which said object is to be manufactured and either a difunctional curable monomer according to Formula (I) or an adhesive polymer binder into an additive manufacturing device; (ii) dispensing selectively positioned droplets of said difunctional curable monomer or adhesive polymer binder, from a printhead of said additive manufacturing device, into a bed of said powder to bind particles of said powder with said difunctional curable monomer or adhesive polymer binder to produce a curable preform having a shape of the object to be manufactured; and, in the case of the difunctional curable monomer, (iii) curing said curable preform to form a crosslinked object. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 15/783574 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/15 (20130101) B22F 3/15 (20130101) B22F 3/1021 (20130101) B22F 10/14 (20210101) B22F 10/14 (20210101) B22F 10/14 (20210101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/30 (20170801) B29C 64/165 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/00 (20141201) B33Y 70/10 (20200101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 122/20 (20130101) C08F 122/1006 (20200201) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/08 (20130101) C08K 3/10 (20130101) C08K 3/22 (20130101) Alloys C22C 33/0207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643066 | Ramakrishnan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | UNITED STATES DEPARTMENT OF ENERGY (Washington, District of Columbia) |
| INVENTOR(S) | Kesavan Ramakrishnan (Columbus, Indiana); Vaidehi Y. Hoshing (Columbus, Indiana) |
| ABSTRACT | Methods and systems of power management in a hybrid vehicle are disclosed. A control system of the hybrid vehicle obtains battery temperature and catalyst temperature. The control system determines (a) whether the battery temperature is within an optimal battery temperature range and (b) whether the catalyst temperature is within an optimal catalyst temperature range. The control system determines a power split ratio (PSR) based on the determination of (a) and (b). The control system controls the engine and the motor-generator based on the determined PSR. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/918481 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/06 (20130101) B60W 10/08 (20130101) B60W 20/16 (20160101) Original (OR) Class B60W 2510/244 (20130101) B60W 2510/246 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 11/002 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3461 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643172 | Siegel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Atargis Energy Corporation (Pueblo, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stefan G. Siegel (Pueblo, Colorado) |
| ABSTRACT | A mooring latch includes a passive foundation portion and a latching portion. The latching portion includes a mechanism, a conical surface shaped to mate with a conical surface of the passive portion, a connector for connection to a mooring structure and permitting rotation about a horizontal axis. The mechanism has a latched configuration that mates the conical surfaces and permits rotations about a shared vertical axis of the conical surfaces. A mooring line threaded through the passive and latching portions and equipped with one or more stops may be used to guide the latching portion to or from the passive portion and to actuate latching or unlatching or the mooring latch. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/149272 |
| ART UNIT | 3617 — Fluid Handling and Dispensing |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 21/04 (20130101) Original (OR) Class B63B 2021/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643698 | Monroe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Alan Monroe (Syracuse, New York); Ibrahim Karaman (College Station, Texas); Raymundo Arroyave (College Station, Texas) |
| ABSTRACT | A controlled thermal coefficient product manufacturing system and method is disclosed. The disclosed product relates to the manufacture of metallic material product (MMP) having a thermal expansion coefficient (TEC) in a predetermined range. The disclosed system and method provides for a first material deformation (FMD) of the MMP that comprises at least some of a first material phase (FMP) wherein the FMP comprises martensite randomly oriented and a first thermal expansion coefficient (FTC). In response to the FMD at least some of the FMP is oriented in at least one predetermined orientation. Subsequent to deformation, the MMP comprises a second thermal expansion coefficient (STC) that is within a predetermined range and wherein the thermal expansion of the MMP is in at least one predetermined direction. The MMP may be comprised of a second material phase (SMP) that may or may not transform to the FMP in response to the FMD. |
| FILED | Monday, September 21, 2020 |
| APPL NO | 17/026880 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 22/20 (20130101) B21D 35/002 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/14 (20130101) B23K 26/38 (20130101) B23K 26/0643 (20130101) B23K 26/0648 (20130101) B23K 26/1476 (20130101) B23K 2101/16 (20180801) B23K 2103/04 (20180801) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/785 (20130101) C21D 8/005 (20130101) C21D 9/0068 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/08 (20130101) C22F 1/10 (20130101) C22F 1/183 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 7/06 (20130101) F27D 11/06 (20130101) F27D 2007/066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643751 | Britt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MATRIX SENSORS, INC. (San Diego, California) |
| ASSIGNEE(S) | MATRIX SENSORS, INC. (San Diego, California) |
| INVENTOR(S) | David K Britt (El Cerrito, California); Paul R Wilkinson (El Segundo, California); Steven Yamamoto (San Diego, California) |
| ABSTRACT | An apparatus and method is provided for coating a surface of a material with a film of porous coordination polymer. A first substrate having a first surface to be coated is positioned in a processing chamber such that the first surface is placed in a substantially opposing relationship to a second surface. In some embodiments, the second surface is provided by a wall of the processing chamber, and in other embodiments the second surface is provided by a second substrate to be coated. The first substrate is held such that a gap exists between the first and second surfaces, and the gap is filled with at least one reaction mixture comprising reagents sufficient to form the crystalline film on at least the first surface. A thin gap (e.g., having a thickness less than 2 mm) between the first and second surfaces is effective for producing a high quality film having a thickness less than 100 μm. Confining the volume of the reaction mixture to a thin layer adjacent the substrate surface significantly reduces problems with sedimentation and concentration control. In some embodiments, the size, shape, or average thickness of the gap is adjusted during formation of the film in response to feedback from at least one film growth monitor. |
| FILED | Wednesday, March 10, 2021 |
| APPL NO | 17/198204 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/00 (20130101) C07F 15/04 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 28/04 (20130101) Original (OR) Class C30B 29/58 (20130101) Weighing G01G 3/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643756 | Agarwal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arvind Agarwal (Miami, Florida); Ambreen Nisar (Miami, Florida); Lihua Lou (Miami, Florida); Benjamin Peter Boesl (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Arvind Agarwal (Miami, Florida); Ambreen Nisar (Miami, Florida); Lihua Lou (Miami, Florida); Benjamin Peter Boesl (Miami, Florida) |
| ABSTRACT | Hybrid carbon nanofiber (Cnf) products (e.g., mats, yarns, webs, etc.) and methods of fabricating the same are provided. The hybrid Cnf products are flexible and lightweight and have high thermal conductivity. An electrospinning process can be used to fabricate the hybrid Cnf products and can include preparation of an electrospinning solution, electrospinning, and carbonization (e.g., under a vacuum condition). |
| FILED | Monday, June 27, 2022 |
| APPL NO | 17/809059 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/203 (20130101) C08J 3/212 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/02 (20130101) D01D 5/003 (20130101) D01D 5/0038 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) D01F 9/22 (20130101) Original (OR) Class D01F 9/225 (20130101) D01F 9/245 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 3/03 (20130101) D04H 3/007 (20130101) Finishing, Dressing, Tentering or Stretching Textile Fabrics D06C 7/04 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/12 (20130101) D10B 2101/122 (20130101) D10B 2503/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644219 | Zhu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Guangdong Zhu (Englewood, Colorado) |
| ABSTRACT | A secondary reflector for receiving light from a plurality of primary reflectors that includes a reflecting surface having a length aligned along a first axis (z), where a cross-section of the reflecting surface in a plane perpendicular to the first axis (z) forms a curve comprising a concave section positioned between a first endpoint and a second endpoint, at least a portion of the concave section is accurately approximated by a polynomial equation, an aperture is formed by a straight line connecting the first endpoint to the second endpoint, and the concave section is configured to focus a plurality of beams of light passing through the aperture onto a focal point. |
| FILED | Tuesday, August 04, 2020 |
| APPL NO | 16/984254 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 23/71 (20180501) F24S 23/72 (20180501) F24S 23/74 (20180501) Original (OR) Class F24S 23/79 (20180501) F24S 23/82 (20180501) F24S 25/00 (20180501) F24S 2023/83 (20180501) F24S 2023/832 (20180501) F24S 2023/834 (20180501) F24S 2023/838 (20180501) F24S 2023/872 (20180501) Optical Elements, Systems, or Apparatus G02B 5/085 (20130101) G02B 19/0023 (20130101) G02B 19/0042 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644301 | Katzenmeyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Aaron Michael Katzenmeyer (Albuquerque, New Mexico); Christopher Todd DeRose (Albuquerque, New Mexico) |
| ABSTRACT | A system and method are provided for optical homodyne detection in an optical fiber interferometer. A detection signal is obtained by interfering an optical data signal with a phase-modulated optical reference signal. The modulator for the optical reference signal is phase-locked to an oscillatory modulation waveform. In embodiments, the modulator includes a piezoelectric element. In more specific embodiments, the modulator is a piezoelectric optical fiber-stretcher. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/540500 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02015 (20130101) Original (OR) Class G01B 9/02067 (20130101) G01B 2290/45 (20130101) G01B 2290/60 (20130101) G01B 2290/70 (20130101) Transmission H04B 10/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644462 | Sava Gallis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Dorina F. Sava Gallis (Albuquerque, New Mexico); Kimberly Butler (Albuquerque, New Mexico) |
| ABSTRACT | Metal-organic frameworks (MOFs) comprising amines on the organic linker can be used for cell targeting. In particular, primary amine groups represent one of the most versatile chemical moieties for conjugation to biologically relevant molecules, including antibodies and enzymes. Different chemical conjugation schemes can be used to conjugate biological molecules to the amino functionality on the organic linker. For example, carbodiimide chemistry can be used to link a primary amine to available carboxyl groups on the protein. For example, sulfhydryl crosslinking chemistry can be used via Traut's reagent scheme. As a demonstration of the invention, the ability of EpCAM antibody-targeted MOFs to bind to a human epithelial cell line (A549), a common target for imaging studies, was confirmed with confocal microscopy. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/243417 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/544 (20130101) G01N 33/54353 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645073 | Kalamatianos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| ASSIGNEE(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| INVENTOR(S) | John Kalamatianos (Boxborough, Massachusetts); Krishnan V. Ramani (Santa Clara, California); Susumu Mashimo (Fukuoka, Japan) |
| ABSTRACT | Address-based filtering for load/store speculation includes maintaining a filtering table including table entries associated with ranges of addresses; in response to receiving an ordering check triggering transaction, querying the filtering table using a target address of the ordering check triggering transaction to determine if an instruction dependent upon the ordering check triggering transaction has previously been generated a physical address; and in response to determining that the filtering table lacks an indication that the instruction dependent upon the ordering check triggering transaction has previously been generated a physical address, bypassing a lookup operation in an ordering violation memory structure to determine whether the instruction dependent upon the ordering check triggering transaction is currently in-flight. |
| FILED | Friday, April 23, 2021 |
| APPL NO | 17/238844 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/35 (20130101) G06F 9/3842 (20130101) G06F 9/30043 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645538 | Suski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Applied Engineering Concepts, Inc. (Eldersburg, Maryland) |
| ASSIGNEE(S) | APPLIED ENGINEERING CONCEPTS, INC. (Eldersburg, Maryland) |
| INVENTOR(S) | William Charles Suski (Mount Pleasant, South Carolina); Christopher Alan Card (Sykesville, Maryland); Brian Richard Few (Sykesville, Maryland) |
| ABSTRACT | A network authentication system can be configured for sampling a plurality of signal samples from a device on a network, providing the plurality of signal samples to a first machine-learned model that is configured to determine a device fingerprint based at least in part on the plurality of signal samples, and providing the device fingerprint to a second machine-learned model that is configured to classify the device based at least in part on the device fingerprint. |
| FILED | Wednesday, February 17, 2021 |
| APPL NO | 17/177513 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/214 (20230101) G06F 18/2411 (20230101) G06F 18/24765 (20230101) Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) G06N 3/084 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/764 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646407 | Anguchamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zenlabs Energy, Inc. (Fremont, California) |
| ASSIGNEE(S) | Zenlabs Energy, Inc. (Fremont, California) |
| INVENTOR(S) | Yogesh Kumar Anguchamy (Newark, California); Haixia Deng (Fremont, California); Yongbong Han (San Francisco, California); Charan Masarapu (Fremont, California); Sujeet Kumar (Newark, California); Herman A. Lopez (Sunnyvale, California) |
| ABSTRACT | Composite silicon based materials are described that are effective active materials for lithium ion batteries. The composite materials comprise processed, e.g., high energy mechanically milled, silicon suboxide and graphitic carbon in which at least a portion of the graphitic carbon is exfoliated into graphene sheets. The composite materials have a relatively large surface area, a high specific capacity against lithium, and good cycling with lithium metal oxide cathode materials. The composite materials can be effectively formed with a two-step high energy mechanical milling process. In the first milling process, silicon suboxide can be milled to form processed silicon suboxide, which may or may not exhibit crystalline silicon x-ray diffraction. In the second milling step, the processed silicon suboxide is milled with graphitic carbon. Composite materials with a high specific capacity and good cycling can be obtained in particular with balancing of the processing conditions. |
| FILED | Wednesday, December 23, 2020 |
| APPL NO | 17/132279 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/364 (20130101) Original (OR) Class H01M 4/485 (20130101) H01M 4/583 (20130101) H01M 10/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646419 | Sakshaug et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Group14 Technologies, Inc. (Woodinville, Washington) |
| ASSIGNEE(S) | GROUP 14 TECHNOLOGIES, INC. (Woodinville, Washington) |
| INVENTOR(S) | Avery Sakshaug (Snohomish, Washington); Henry R. Costantino (Woodinville, Washington); Aaron M. Feaver (Seattle, Washington); Leah A. Thompkins (Seattle, Washington); Katharine Geramita (Seattle, Washington); Benjamin E. Kron (Seattle, Washington); Sarah Fredrick (Denver, Colorado); Farshid Afkhami (Lake Stevens, Washington); Adam Strong (Lake Forest Park, Washington) |
| ABSTRACT | Composites of silicon and various porous scaffold materials, such as carbon material comprising micro-, meso- and/or macropores, and methods for manufacturing the same are provided. The compositions find utility in various applications, including electrical energy storage electrodes and devices comprising the same. |
| FILED | Wednesday, August 17, 2022 |
| APPL NO | 17/890197 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/522 (20130101) C04B 35/524 (20130101) C04B 38/0051 (20130101) C04B 38/0054 (20130101) C04B 38/0064 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/85 (20130101) C04B 41/4529 (20130101) C04B 41/5096 (20130101) C04B 41/5096 (20130101) C04B 2111/00853 (20130101) C04B 2235/428 (20130101) C04B 2235/616 (20130101) C04B 2235/6581 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/362 (20130101) H01M 4/364 (20130101) H01M 4/366 (20130101) H01M 4/386 (20130101) H01M 4/0416 (20130101) H01M 4/587 (20130101) Original (OR) Class H01M 4/625 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101) H01M 2220/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646437 | Bazzarella et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | 24M Technologies, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | 24M Technologies, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Ricardo Bazzarella (Woburn, Massachusetts); Alexander H. Slocum (Bow, New Hampshire); Tristan Doherty (Somerville, Massachusetts); James C. Cross, III (Carlisle, Massachusetts) |
| ABSTRACT | Electrochemical cells and methods of making electrochemical cells are described herein. In some embodiments, an apparatus includes a multi-layer sheet for encasing an electrode material for an electrochemical cell. The multi-layer sheet including an outer layer, an intermediate layer that includes a conductive substrate, and an inner layer disposed on a portion of the conductive substrate. The intermediate layer is disposed between the outer layer and the inner layer. The inner layer defines an opening through which a conductive region of the intermediate layer is exposed such that the electrode material can be electrically connected to the conductive region. Thus, the intermediate layer can serve as a current collector for the electrochemical cell. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 17/402059 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0404 (20130101) Original (OR) Class H01M 10/0413 (20130101) H01M 10/0436 (20130101) H01M 10/0525 (20130101) H01M 50/105 (20210101) H01M 50/124 (20210101) H01M 50/545 (20210101) H01M 50/553 (20210101) H01M 2220/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646444 | Visco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Lutgard C. De Jonghe (Lafayette, California); Bruce D. Katz (Moraga, California); Vitaliy Nimon (San Francisco, California) |
| ABSTRACT | A lithium ion-conductive solid electrolyte including a freestanding inorganic vitreous sheet of sulfide-based lithium ion conducting glass is capable of high performance in a lithium metal battery by providing a high degree of lithium ion conductivity while being highly resistant to the initiation and/or propagation of lithium dendrites. Such an electrolyte is also itself manufacturable, and readily adaptable for battery cell and cell component manufacture, in a cost-effective, scalable manner. |
| FILED | Thursday, October 01, 2020 |
| APPL NO | 16/948835 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 50/44 (20210101) H01M 50/437 (20210101) H01M 50/489 (20210101) H01M 50/497 (20210101) H01M 2300/0068 (20130101) H01M 2300/0071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646445 | Visco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Lutgard C. De Jonghe (Lafayette, California); Bruce D. Katz (Moraga, California); Vitaliy Nimon (San Francisco, California) |
| ABSTRACT | A standalone lithium ion-conductive solid electrolyte including a freestanding inorganic vitreous sheet of sulfide-based lithium ion conducting glass is capable of high performance in a lithium metal battery by providing a high degree of lithium ion conductivity while being highly resistant to the initiation and/or propagation of lithium dendrites. Such an electrolyte is also itself manufacturable, and readily adaptable for battery cell and cell component manufacture, in a cost-effective, scalable manner. |
| FILED | Thursday, October 01, 2020 |
| APPL NO | 16/948836 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 17/06 (20130101) C03B 17/064 (20130101) C03B 17/067 (20130101) C03B 23/037 (20130101) C03B 23/245 (20130101) C03B 33/0235 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/19 (20130101) C03C 3/321 (20130101) C03C 4/18 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646472 | Visco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Bruce D. Katz (Moraga, California); Yevgeniy S. Nimon (Danville, California); Lutgard C. De Jonghe (Lafayette, California) |
| ABSTRACT | Active metal and active metal intercalation electrode structures and battery cells having ionically conductive protective architecture including an active metal (e.g., lithium) conductive impervious layer separated from the electrode (anode) by a porous separator impregnated with a non-aqueous electrolyte (anolyte). This protective architecture prevents the active metal from deleterious reaction with the environment on the other (cathode) side of the impervious layer, which may include aqueous or non-aqueous liquid electrolytes (catholytes) and/or a variety electrochemically active materials, including liquid, solid and gaseous oxidizers. Safety additives and designs that facilitate manufacture are also provided. |
| FILED | Tuesday, January 05, 2021 |
| APPL NO | 17/248024 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/06 (20130101) H01G 11/52 (20130101) H01G 11/58 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/366 (20130101) H01M 4/587 (20130101) H01M 4/628 (20130101) H01M 6/34 (20130101) H01M 8/065 (20130101) H01M 10/36 (20130101) H01M 10/052 (20130101) H01M 10/0562 (20130101) H01M 12/08 (20130101) H01M 50/46 (20210101) Original (OR) Class H01M 50/449 (20210101) H01M 2004/027 (20130101) H01M 2300/0085 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646671 | Teeneti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chakridhar Reddy Teeneti (North Logan, Utah); Regan A. Zane (Hyde Park, Utah); Hongjie Wang (North Logan, Utah); Dorai Babu Yelaverthi (Raleigh, North Carolina) |
| ASSIGNEE(S) | Utah State University (Logan, Utah) |
| INVENTOR(S) | Chakridhar Reddy Teeneti (North Logan, Utah); Regan A. Zane (Hyde Park, Utah); Hongjie Wang (North Logan, Utah); Dorai Babu Yelaverthi (Raleigh, North Carolina) |
| ABSTRACT | An power converter includes an unfolder connected to a three-phase source and has an output connection with a positive terminal, a negative terminal and a neutral terminal. The unfolder creates two unipolar piece-wise sinusoidal DC voltage waveforms offset by a half of a period. A three-input converter connected to the unfolder produces a quasi-sinusoidal output voltage across output terminals. Switches of the converter selectively connect the positive, negative and neutral inputs across the output terminals. A PWM controller controls a first duty ratio and a second duty ratio for the converter based on a phase angle of the source and a modulation index generated from an error signal related to a control variable. The duty ratios are time varying with a fundamental frequency of the source. The modulation index relates to output voltage of the converter, peak voltage or current of the source and/or peak current at the output terminals. |
| FILED | Tuesday, October 12, 2021 |
| APPL NO | 17/499735 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/007 (20210501) H02M 1/4216 (20130101) H02M 5/225 (20130101) H02M 5/2932 (20210501) Original (OR) Class H02M 7/5395 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646896 | Crosby et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Sean Michael Crosby (Albuquerque, New Mexico); William Marchetto, II (Albuquerque, New Mexico); Kurt Daniel Brenning (Albuquerque, New Mexico) |
| ABSTRACT | A system for generating and authenticating remote sensing imagery includes a remote sensing platform. The remote sensing platform includes an imaging sensor and a hardware logic device that is directly coupled to the imaging sensor. The hardware logic device receives image data from the imaging sensor and generates a cryptographic signature based upon the image data. The hardware logic device outputs a signed image that includes the image data and the cryptographic signature. A computing device operated by a downstream user receives the signed image and can determine whether the image data has been modified from its original content based upon the cryptographic signature. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231377 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) Original (OR) Class H04L 9/3278 (20130101) Pictorial Communication, e.g Television H04N 1/32144 (20130101) H04N 7/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11647643 | Li |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jian Li (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jian Li (Tempe, Arizona) |
| ABSTRACT | An organic light emitting device including an emissive layer including a blue phosphorescent emitter, an electron transport layer, and a hole blocking layer between the emissive layer and the electron transport layer, wherein the hole blocking layer comprises a tetradentate palladium complex. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/756207 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0072 (20130101) H01L 51/0074 (20130101) H01L 51/0081 (20130101) H01L 51/0087 (20130101) H01L 51/5016 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5096 (20130101) Original (OR) Class H01L 2251/552 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11641857 | Cutler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakand, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Sean R. Cutler (Riverside, California); Aditya Vaidya (Riverside, California) |
| ABSTRACT | The present invention sets forth new compounds that potently block activation of ABA receptors. In some aspects, these compounds can be used to enhance germination of crop seeds to stand establishment and to increase transpiration and photosynthetic yields when water is not limiting plant growth. |
| FILED | Friday, June 19, 2020 |
| APPL NO | 16/906765 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/647 (20130101) Original (OR) Class Heterocyclic Compounds C07D 249/06 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 405/12 (20130101) C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642313 | DeSimone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Jason P. Rolland (Belmont, Massachusetts); Benjamin W. Maynor (Durham, North Carolina); Larken E. Euliss (Augoura Hills, California); Ginger Denison Rothrock (Durham, North Carolina); Ansley E. Dennis (Augusta, Georgia); Edward T. Samulski (Chapel Hill, North Carolina); R. Jude Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique. |
| FILED | Wednesday, November 11, 2020 |
| APPL NO | 17/095301 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) Original (OR) Class A61K 9/0097 (20130101) A61K 9/5138 (20130101) A61K 9/5153 (20130101) A61K 9/5192 (20130101) A61K 47/34 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 99/0085 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0004 (20130101) H01L 51/0021 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/3154 (20150401) Y10T 428/24273 (20150115) Y10T 428/24479 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642642 | Oakey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| INVENTOR(S) | John Oakey (Laramie, Wyoming); Katie Dongmei Li-Oakey (Laramie, Wyoming); Daniel Debroy (Laramie, Wyoming); Carl Frick (Laramie, Wyoming); Rajib Shaha (Laramie, Wyoming) |
| ABSTRACT | Described are methods and devices for the generation of hydrogel particles with micrometer and submicrometer dimensions using oxygen-inhibited partial polymerization, and the particles generated therefrom. The described methods generate particles with dimensions independent of the starting polymerizable solution dimension, for example, a microdroplet. Further, microfluidic flow parameters (e.g. viscosity, flow rate) and photopolymerization process parameters (e.g. optical exposure intensity and duration) are controlled to generate particles with tunable crosslinking density-determined properties including elasticity, diffusivity, and biomolecular display for diverse applications such as drug delivery, tissue engineering cell scaffolds, and single- and multiple- cell therapeutics. Similarly, gradients of crosslinking density-determined properties can be created within single particles through the selection of optical exposure intensity and duration. In addition to conventional spherical shapes, a suite of non-spherical shapes may be generated by manipulating the dimensions of the microfluidic channels and other related physical and process parameters. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/647869 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1635 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/14 (20130101) Original (OR) Class B01J 13/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642671 | Moon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Hyejin Moon (Austin, Texas); Shubhodeep Paul (Austin, Texas) |
| ABSTRACT | A method and system for performing biomolecule extraction are provided that use liquid-to-liquid extraction (LLE) in combination with an electrowetting on dielectric (EWOD) device to provide a biomolecule extraction solution that has high extraction efficiency and that is less costly and easier to use than current state of the art methods and systems. The system and method are well suited for, but not limited to, extraction of DNA, RNA and protein molecules. |
| FILED | Monday, June 27, 2022 |
| APPL NO | 17/850242 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 11/0496 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2400/0427 (20130101) Peptides C07K 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642835 | Hoelzle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | David J. Hoelzle (Columbus, Ohio); Desmond M. D'Souza (Columbus, Ohio); Andrej Simeunovic (Columbus, Ohio); Ali Asghari Adib (Columbus, Ohio) |
| ABSTRACT | The present disclosure provides methods for freeform extrusion-based additive manufacturing via a robotic arm. In specific aspects, methods are particularly provided for minimally invasive, intracorporeal three-dimensional printing of biocompatible materials. An end effector of a robotic arm includes a sharp member and a reservoir filled with a printing material. The provided method may include piercing a substrate with the sharp member. A bulb or microbolus of material may be extruded beneath the substrate surface to act as an anchor. The end effector may be manipulated to extrude biomaterial along a printing path. Periodically along the printing path, the sharp member is used to pierce the substrate surface create additional respective anchors. In some instances, the method may terminate after extruding material to form a single layer construct. In other instances, the method includes forming one or more layers on top of the initial base layer anchored to the substrate. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 17/600950 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/0061 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642839 | Nussbaum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Justin Nussbaum (Knoxville, Tennessee); Nathan Crane (Lutz, Florida) |
| ABSTRACT | The disclosed subject matter relates to method for increasing the molecular weight of a polymer material during an additive manufacturing process. The method can comprise disposing a first layer of the polymer material at a target surface; exposing the first layer of the polymer material to an energy source for a sufficient period of time to sinter or melt and undergo a condensation reaction at least at a portion of the polymer material; controlling the condensation reaction to allow a desired increased number average molecular weight of the polymer material; and repeating the method steps to form an object in a layerwise fashion. Controlling the condensation reaction can comprise controlling and/or adjusting an energy 10 source-related parameter, a polymer-related parameter, a temperature related parameter, a vacuum related parameter, a process duration, a processing gas, an air flow volume and/or speed, or a combination thereof. |
| FILED | Monday, July 22, 2019 |
| APPL NO | 17/277949 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) Original (OR) Class B29C 64/245 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/10 (20200101) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643366 | Gardiner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Christopher Joseph Gardiner (St. Petersburg, Florida); Justin Nussbaum (Tampa, Florida); Nathan Crane (Lutz, Florida) |
| ABSTRACT | A large area sintering platform, system, and methodology. The system includes a convection oven with a projection window disposed within a top surface of the oven. A platform is disposed within the oven below the window at a spaced distance away from the window. A powder is positioned on top of the platform, with a thermocouple positioned within the powder on the platform. A high intensity projector moves in sync with the platform, and uses low intensities and long exposure times to project an image through the window onto the powder and sinter the powder to fabricate the desired model layer by layer. |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/637448 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/28 (20210101) B22F 10/368 (20210101) B22F 12/13 (20210101) B22F 12/44 (20210101) B22F 12/90 (20210101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) B29C 64/264 (20170801) B29C 64/295 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/00 (20141201) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643443 | Joshi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Neel Satish Joshi (Somerville, Massachusetts); Noémie-Manuelle Dorval Courchesne (Cambridge, Massachusetts) |
| ABSTRACT | Methods of making engineered protein-based materials, nanofibers, and biofilms from bacterial amyloid-based structures that are capable of mediating long-range electron transport are provided. |
| FILED | Friday, November 18, 2016 |
| APPL NO | 15/777070 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 14/195 (20130101) C07K 14/245 (20130101) Original (OR) Class C07K 14/395 (20130101) C07K 14/4711 (20130101) C07K 14/4717 (20130101) C07K 2319/00 (20130101) C07K 2319/20 (20130101) C07K 2319/21 (20130101) C07K 2319/23 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0065 (20130101) C12N 9/2462 (20130101) Enzymes C12Y 111/01007 (20130101) C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643659 | Marcucci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CITY OF HOPE (Duarte, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Guido Marcucci (Duarte, California); Ya-Huei Kuo (Duarte, California); Si-ping Han (Duarte, California); Lisa Scherer (Duarte, California); William A. Goddard, III (Pasadena, California); John Rossi (Duarte, California) |
| ABSTRACT | Disclosed herein are conditional siRNAs activatable by CBFβ-MYH11 oncogenic gene and use thereof for treating conditions such as acute myeloid leukemia (AML). The conditional siRNAs target MCL-1 or HDAC8. |
| FILED | Monday, February 10, 2020 |
| APPL NO | 16/786793 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/3519 (20130101) C12N 2320/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643698 | Monroe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Alan Monroe (Syracuse, New York); Ibrahim Karaman (College Station, Texas); Raymundo Arroyave (College Station, Texas) |
| ABSTRACT | A controlled thermal coefficient product manufacturing system and method is disclosed. The disclosed product relates to the manufacture of metallic material product (MMP) having a thermal expansion coefficient (TEC) in a predetermined range. The disclosed system and method provides for a first material deformation (FMD) of the MMP that comprises at least some of a first material phase (FMP) wherein the FMP comprises martensite randomly oriented and a first thermal expansion coefficient (FTC). In response to the FMD at least some of the FMP is oriented in at least one predetermined orientation. Subsequent to deformation, the MMP comprises a second thermal expansion coefficient (STC) that is within a predetermined range and wherein the thermal expansion of the MMP is in at least one predetermined direction. The MMP may be comprised of a second material phase (SMP) that may or may not transform to the FMP in response to the FMD. |
| FILED | Monday, September 21, 2020 |
| APPL NO | 17/026880 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 22/20 (20130101) B21D 35/002 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/14 (20130101) B23K 26/38 (20130101) B23K 26/0643 (20130101) B23K 26/0648 (20130101) B23K 26/1476 (20130101) B23K 2101/16 (20180801) B23K 2103/04 (20180801) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/785 (20130101) C21D 8/005 (20130101) C21D 9/0068 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/08 (20130101) C22F 1/10 (20130101) C22F 1/183 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 7/06 (20130101) F27D 11/06 (20130101) F27D 2007/066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644682 | O'Toole et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Matthew O'Toole (Pittsburgh, Pennsylvania); Mark Sheinin (Pittsburgh, Pennsylvania); Srinivasa Narasimhan (Pittsburgh, Pennsylvania) |
| ABSTRACT | A novel class of imaging systems that combines diffractive optics with 1D line sensing is disclosed. When light passes through a diffraction grating or prism, it disperses as a function of wavelength. This property is exploited to recover 2D and 3D positions from line images. A detailed image formation model and a learning-based algorithm for 2D position estimation are disclosed. The disclosure includes several extensions of the imaging system to improve the accuracy of the 2D position estimates and to expand the effective field-of-view. The invention is useful for fast passive imaging of sparse light sources, such as streetlamps, headlights at night and LED-based motion capture, and structured light 3D scanning with line illumination and line sensing. |
| FILED | Thursday, February 18, 2021 |
| APPL NO | 17/178855 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/002 (20130101) G01B 11/03 (20130101) Optical Elements, Systems, or Apparatus G02B 5/18 (20130101) G02B 27/0944 (20130101) G02B 27/4233 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645380 | Chittamuru et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Sai Vineel Reddy Chittamuru (Fort Collins, Colorado); Sudeep Pasricha (Fort Collins, Colorado); Ishan Thakkar (Fort Collins, Colorado) |
| ABSTRACT | The exemplified methods and systems provide hardware-circuit-level encryption for inter-core communication of photonic communication devices such as photonic network-on-chip devices. In some embodiments, the hardware-circuit level encryption uses authentication signatures that are based on process variation that inherently occur during the fabrication of the photonic communication device. The hardware level encryption can facilitate high bandwidth on-chip data transfers while preventing hardware-based trojans embedded in components of the photonic communication device such as PNoC devices or preventing external snooping devices from snooping data from the neighboring photonic signal transmission medium in a shared photonic signal transmission medium. In some embodiments, the hardware-circuit-level encryption is used for unicast/multicast traffic. |
| FILED | Friday, June 07, 2019 |
| APPL NO | 16/434420 |
| ART UNIT | 2496 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 15/7825 (20130101) G06F 21/44 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) Wireless Communication Networks H04W 4/06 (20130101) H04W 12/069 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645835 | Greenblatt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Aaron Benjamin Greenblatt (Stoughton, Massachusetts); Sos S. Agaian (San Antonio, Texas) |
| ABSTRACT | A method and system for creating hypercomplex representations of data includes, in one exemplary embodiment, at least one set of training data with associated labels or desired response values, transforming the data and labels into hypercomplex values, methods for defining hypercomplex graphs of functions, training algorithms to minimize the cost of an error function over the parameters in the graph, and methods for reading hierarchical data representations from the resulting graph. Another exemplary embodiment learns hierarchical representations from unlabeled data. The method and system, in another exemplary embodiment, may be employed for biometric identity verification by combining multimodal data collected using many sensors, including, data, for example, such as anatomical characteristics, behavioral characteristics, demographic indicators, artificial characteristics. In other exemplary embodiments, the system and method may learn hypercomplex function approximations in one environment and transfer the learning to other target environments. Other exemplary applications of the hypercomplex deep learning framework include: image segmentation; image quality evaluation; image steganalysis; face recognition; event embedding in natural language processing; machine translation between languages; object recognition; medical applications such as breast cancer mass classification; multispectral imaging; audio processing; color image filtering; and clothing identification. |
| FILED | Thursday, August 30, 2018 |
| APPL NO | 16/117415 |
| ART UNIT | 2621 — Selective Visual Display Systems |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/627 (20130101) G06K 9/6257 (20130101) G06K 9/6289 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/082 (20130101) G06N 3/0445 (20130101) G06N 3/0454 (20130101) G06N 3/0481 (20130101) G06N 5/046 (20130101) Image or Video Recognition or Understanding G06V 10/98 (20220101) G06V 10/454 (20220101) G06V 20/13 (20220101) G06V 20/64 (20220101) G06V 20/194 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11645939 | Delson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); NATIONAL SCIENCE FOUNDATION (Alexandria, Virginia) |
| INVENTOR(S) | Nathan Delson (San Diego, California) |
| ABSTRACT | A computer-based method and system for teaching educational sketching includes receiving a user-generated image created in response to a learning assignment and comparing the user-generated image to a solution image to identify one or more errors in the user-generated image relative to the solution image, where the errors may include additional image elements and missing image elements. Comparing is performed by providing a solution region corresponding to an acceptable variation from the solution image and identifying one or more errors based on a presence or absence of at least a portion of a corresponding element of the user-generated image within the solution region. If errors are identified and a non-passing status is determined, a hint is displayed to the user. The hint may be the correct elements of the user-generated image, a portion of the solution image, or a combination thereof. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/701012 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Electric Digital Data Processing G06F 3/04883 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 2207/30168 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/02 (20130101) G09B 11/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646191 | Jarrold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | The Trustees Of Indiana University (Bloomington, Indiana) |
| INVENTOR(S) | Martin F. Jarrold (Bloomington, Oregon); Joanna A. Hogan (Hillsboro, Oregon) |
| ABSTRACT | An instrument for separating ions may include an ion source configured to generate ions from a sample, at least one ion separation instrument configured to separate the generated ions as a function of at least one molecular characteristic and an electrostatic linear ion trap (ELIT) positioned to receive ions exiting the at least one ion separation instrument. The ELIT has first and second ion mirrors separated by a charge detection cylinder, and is configured such that an ion trapped therein oscillates back and forth through the charge detection cylinder between the first and second ion mirrors with a duty cycle, corresponding to a ratio of time spent by the trapped ion traversing the charge detection cylinder and total time spent by the trapped ion traversing a combination of the first and second ion mirrors and the charge detection cylinder during one complete oscillation cycle, of approximately 50%. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/468791 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/025 (20130101) H01J 49/0036 (20130101) H01J 49/48 (20130101) H01J 49/4245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646693 | Agrawal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rakesh Agrawal (West Lafayette, Indiana); Peter Andrew Bermel (West Lafayette, Indiana); Allison Perna (Berthoud, Colorado) |
| ASSIGNEE(S) | NATIONAL SCIENCE FOUNDATION (Alexandria, Virginia) |
| INVENTOR(S) | Rakesh Agrawal (West Lafayette, Indiana); Peter Andrew Bermel (West Lafayette, Indiana); Allison Perna (Berthoud, Colorado) |
| ABSTRACT | A photovoltaic system for generating electrical power on farmland while minimizing reduction of solar radiation incident on ground due to shadowing, including a photovoltaic module having a first photovoltaic face defining a first plane, a normal axis extending from the first plane, a first pivot axis extending through the photovoltaic module, a second pivot axis extending through the photovoltaic module, at least one motor operationally connected to pivot the photovoltaic module about at least one pivot axis, and an electronic controller operationally connected to at least one motor. An incident solar ray strikes the photovoltaic module at an angle of incidence defined as an intersection of the incident solar ray and the normal axis. The electronic controller sends signals to the at least one motor to maintain the angle of incidence as close as possible to ninety degrees. |
| FILED | Wednesday, August 19, 2020 |
| APPL NO | 16/997386 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/32 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646872 | Brooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clemson University (Clemson, South Carolina) |
| ASSIGNEE(S) | Clemson University (Clemson, South Carolina); University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Richard R. Brooks (Clemson, South Carolina); Lu Yu (Clemson, South Carolina); Anthony Skjellum (Knoxville, Tennessee) |
| ABSTRACT | The system can be for the management of access authorization using an immutable ledger comprising and can include a server having a computer readable medium in communications with an immutable ledger. A set of computer readable instructions can be included in the server and can be configured for: receiving a set of data, encrypting the set of data with a data-encryption-key and storing the encrypted data on the immutable ledger, creating a key tree having a node associated with a user, creating a key-encryption-key associated with the node and the user, and, distributing the key-encryption-key to the user wherein the key-encryption-key is configured to decrypt the data-encryption-key thereby providing access to the data for the user. |
| FILED | Tuesday, April 20, 2021 |
| APPL NO | 17/235279 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/6209 (20130101) G06F 21/6218 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/50 (20220501) H04L 9/0822 (20130101) Original (OR) Class H04L 9/0836 (20130101) H04L 9/0894 (20130101) H04L 9/3297 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11642455 | Green et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ViaCyte, Inc. (San Diego, California) |
| ASSIGNEE(S) | ViaCyte, Inc. (San Diego, California) |
| INVENTOR(S) | Chad Green (San Diego, California); Laura Martinson (San Diego, California); Erik Olson (San Diego, California); Val Anthony Bellora (San Diego, California); Leah Elliott (San Diego, California); Richard Alexander Grant (San Diego, California); Donald Koenig (San Diego, California); Giacomo Strollo (San Diego, California) |
| ABSTRACT | Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551536 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/022 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/14276 (20130101) Original (OR) Class A61M 37/0069 (20130101) A61M 2209/045 (20130101) Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking B65B 3/003 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11644219 | Zhu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Guangdong Zhu (Englewood, Colorado) |
| ABSTRACT | A secondary reflector for receiving light from a plurality of primary reflectors that includes a reflecting surface having a length aligned along a first axis (z), where a cross-section of the reflecting surface in a plane perpendicular to the first axis (z) forms a curve comprising a concave section positioned between a first endpoint and a second endpoint, at least a portion of the concave section is accurately approximated by a polynomial equation, an aperture is formed by a straight line connecting the first endpoint to the second endpoint, and the concave section is configured to focus a plurality of beams of light passing through the aperture onto a focal point. |
| FILED | Tuesday, August 04, 2020 |
| APPL NO | 16/984254 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 23/71 (20180501) F24S 23/72 (20180501) F24S 23/74 (20180501) Original (OR) Class F24S 23/79 (20180501) F24S 23/82 (20180501) F24S 25/00 (20180501) F24S 2023/83 (20180501) F24S 2023/832 (20180501) F24S 2023/834 (20180501) F24S 2023/838 (20180501) F24S 2023/872 (20180501) Optical Elements, Systems, or Apparatus G02B 5/085 (20130101) G02B 19/0023 (20130101) G02B 19/0042 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646407 | Anguchamy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zenlabs Energy, Inc. (Fremont, California) |
| ASSIGNEE(S) | Zenlabs Energy, Inc. (Fremont, California) |
| INVENTOR(S) | Yogesh Kumar Anguchamy (Newark, California); Haixia Deng (Fremont, California); Yongbong Han (San Francisco, California); Charan Masarapu (Fremont, California); Sujeet Kumar (Newark, California); Herman A. Lopez (Sunnyvale, California) |
| ABSTRACT | Composite silicon based materials are described that are effective active materials for lithium ion batteries. The composite materials comprise processed, e.g., high energy mechanically milled, silicon suboxide and graphitic carbon in which at least a portion of the graphitic carbon is exfoliated into graphene sheets. The composite materials have a relatively large surface area, a high specific capacity against lithium, and good cycling with lithium metal oxide cathode materials. The composite materials can be effectively formed with a two-step high energy mechanical milling process. In the first milling process, silicon suboxide can be milled to form processed silicon suboxide, which may or may not exhibit crystalline silicon x-ray diffraction. In the second milling step, the processed silicon suboxide is milled with graphitic carbon. Composite materials with a high specific capacity and good cycling can be obtained in particular with balancing of the processing conditions. |
| FILED | Wednesday, December 23, 2020 |
| APPL NO | 17/132279 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/04 (20130101) H01M 4/364 (20130101) Original (OR) Class H01M 4/485 (20130101) H01M 4/583 (20130101) H01M 10/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11643394 | Mallipattu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); Icahn School of Medicine at Mount Sinai (New York, New York); The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Sandeep Mallipattu (St. James, New York); Bhaskar Das (West Nyack, New York) |
| ABSTRACT | The present disclosure is concerned with small molecule modulators of KLF15 signaling useful for treating various disorders such as, for example, kidney disease (e.g., chronic kidney disease), heart disease, obesity, or a neurodegenerative disorder (e.g., amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, traumatic brain injury, vascular dementia, Huntington's disease, mental retardation, and attention deficit and hyperactivity disorder (ADHD)). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244762 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) Acyclic or Carbocyclic Compounds C07C 321/20 (20130101) Heterocyclic Compounds C07D 213/74 (20130101) C07D 213/85 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11643656 | Bell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Robert J. A. Bell (Oakland, California); Joseph F. Costello (Oakland, California); Daniel Lim (Oakland, California); Andrew Mancini (Oakland, California) |
| ABSTRACT | The present invention provides methods for cancers associated with a TERT promoter mutation in a subject. In some embodiments, the methods comprise administering to the subject a therapeutically effective amount of an agent that specifically reduces or inhibits GA binding protein transcription factor beta subunit 1 long isoform (GABPBIL) expression or function. |
| FILED | Thursday, May 24, 2018 |
| APPL NO | 16/615287 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 31/7088 (20130101) A61K 45/06 (20130101) A61K 47/6807 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/3231 (20130101) C12N 2310/3513 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11644364 | Moore |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Louisiana Tech Research Corporation (Ruston, Louisiana) |
| ASSIGNEE(S) | Louisiana Tech Research Corporation (Ruston, Louisiana) |
| INVENTOR(S) | Arden Moore (Ruston, Louisiana) |
| ABSTRACT | A thermopile sensor including a uniform substrate having a first surface with a first section and a second section at an elevation varying relative to the first section by between about 5 micrometers and about 500 micrometers. The sensor further includes a plurality of thermopile junctions, with each junction having (i) a first strip of a first conductive material, extending from the first section to the second section, (ii) a second strip of a second conductive material, forming an electrical junction with the first strip on the second section and extending to the first section, and (iii) with the thermopile junctions being connected in series. A first contact pad on the substrate is connected to an initial thermopile junction and a second contact pad on the substrate is connected to a last thermopile junction, with conductors connecting to the first and second contact pads and extending off of the substrate. |
| FILED | Thursday, July 18, 2019 |
| APPL NO | 16/515857 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/14 (20130101) Original (OR) Class G01J 5/046 (20130101) G01J 5/0205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646679 | Choi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Sang H. Choi (Poquoson, Virginia); Dennis M. Bushnell (Hampton, Virginia); Adam J. Duzik (Rockledge, Florida) |
| ABSTRACT | Various aspects include electric generators configured to boost electrical output by leveraging electron avalanche generated by a high energy photon radiation source. In various aspects, an electric generator includes a stator and a rotor positioned within the stator, wherein the stator and rotor are configured to generate electric current when the rotor is rotated, and a high energy photon source (e.g., a gamma ray source) positioned and configured to irradiate at least a portion of conductors in the rotor or stator. In some aspects, the stator generates a magnetic field when the electric generator is operating, and the rotor includes armature windings configured to generate electric current when the rotor is rotated. In some aspects, the high energy photon source includes cobalt-60 and/or cesium-137. |
| FILED | Tuesday, April 20, 2021 |
| APPL NO | 17/235497 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 1/04 (20130101) G21H 1/12 (20130101) Electric Machines Not Otherwise Provided for H02N 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11642371 | Seto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADVANTAGE SILVER DENTAL ARREST, LLC (Salem, Oregon) |
| ASSIGNEE(S) | ADVANTAGE SILVER DENTAL ARREST, LLC (Salem, Oregon) |
| INVENTOR(S) | Jong Seto (San Francisco, California); Peter M. Milgrom (Seattle, Washington) |
| ABSTRACT | The invention provides compositions and methods that comprise encapsulated silver diamine fluoride or other antimicrobial materials for use in treatment of dental caries, for example. |
| FILED | Tuesday, December 01, 2020 |
| APPL NO | 17/108947 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/501 (20130101) A61K 9/5073 (20130101) A61K 9/5089 (20130101) A61K 33/38 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/02 (20130101) A61K 47/16 (20130101) A61K 47/32 (20130101) A61K 47/34 (20130101) A61K 47/46 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11642391 | Mann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vascular BioSciences (San Diego, California); Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California); David Mann (San Diego, California); Erkki Ruoslahti (La Jolla, California); Masanobu Komatsu (La Jolla, California) |
| ASSIGNEE(S) | Vascular Biosciences (San Diego, California) |
| INVENTOR(S) | David Mann (San Diego, California); Erkki Ruoslahti (La Jolla, California); Masanobu Komatsu (La Jolla, California) |
| ABSTRACT | Compositions and methods useful for delivery of targeted therapies for pulmonary arterial hypertension, sepsis, cancer and cachexia. The compositions and methods are based on peptide pharmacophores that selectively bind to and home to diseased tissue and enable targeted therapies to affect a beneficial therapeutic result. Peptide pharmacophores may selectively target tumor vasculature, regenerating tissue, wounded tissue, inflamed tissue, fibrotic tissue, remodeled tissue, tissue characterized by elevated heparanase levels, and have the ability to internalize into such diseased cells. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 15/502170 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/222 (20130101) A61K 31/222 (20130101) A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/436 (20130101) A61K 31/438 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 38/08 (20130101) A61K 38/12 (20130101) Original (OR) Class A61K 38/55 (20130101) A61K 45/06 (20130101) A61K 47/64 (20170801) A61K 47/643 (20170801) A61K 47/6811 (20170801) A61K 47/6851 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 9/12 (20180101) A61P 11/00 (20180101) A61P 13/12 (20180101) A61P 31/00 (20180101) A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/15 (20130101) G01N 33/5008 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 35/00 (20190201) G16B 35/10 (20190201) G16B 35/20 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/60 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11641864 | Ukuku |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Dike O. Ukuku (Philadelphia, Pennsylvania) |
| ABSTRACT | A synergistic composition of oxalic acid, citric acid, ascorbic acid, lactic acid, and hydrogen peroxide that has a combination of antimicrobial and antibrowning properties. |
| FILED | Monday, September 14, 2020 |
| APPL NO | 17/020363 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 7/10 (20130101) A23B 7/154 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/3508 (20130101) Original (OR) Class A23L 3/34635 (20130101) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11647274 | Vemury |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | Systems and methods are disclosed and an example system includes a digital image receiver for receiving a digital image, and an automatic obscuration processor coupled to the image receiver and configured to determine whether the digital image includes a region that classifies as an image of a category of object and, upon a positive determination, to obscure the region and output a corresponding obscured-region digital image. |
| FILED | Tuesday, February 01, 2022 |
| APPL NO | 17/590583 |
| ART UNIT | 2696 — Selective Visual Display Systems |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 2207/20008 (20130101) G06T 2207/20224 (20130101) Pictorial Communication, e.g Television H04N 5/272 (20130101) H04N 5/2252 (20130101) H04N 5/23219 (20130101) Original (OR) Class H04N 5/23222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11646802 | Liang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Di Liang (Santa Barbara, California); Zhihong Huang (Palo Alto, California) |
| ABSTRACT | Systems and methods are provided for receiving an optical signal from an optical fiber, including: coupling via an optical coupler the optical signal from an optical fiber into first and second waveguides, wherein the optical signal comprises TE and TM polarized optical signals and the optical coupler couples the TE polarized optical signal into the first waveguide and the TM polarized optical signal into the second waveguide; equalizing the TE and TM polarized optical signals from the coupler to equalize optical power levels of the TE and TM polarized optical signals; optically combining the equalized TE and TM polarized optical signals; and transmitting the combined optical signal to a photodetector. |
| FILED | Tuesday, June 02, 2020 |
| APPL NO | 16/891008 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/2572 (20130101) H04B 10/6151 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 11642455 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ViaCyte, Inc. (San Diego, California) |
| ASSIGNEE(S) | ViaCyte, Inc. (San Diego, California) |
| INVENTOR(S) | Chad Green (San Diego, California); Laura Martinson (San Diego, California); Erik Olson (San Diego, California); Val Anthony Bellora (San Diego, California); Leah Elliott (San Diego, California); Richard Alexander Grant (San Diego, California); Donald Koenig (San Diego, California); Giacomo Strollo (San Diego, California) |
| ABSTRACT | Embodiments herein describe tools, instruments and methods for aseptic loading, dispensing and/or delivering cells into an implantable device and aseptically and selectively sealing a device inside a sterile package as well as and storing and preparing for shipment the cell-filled device. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551536 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/022 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/14276 (20130101) Original (OR) Class A61M 37/0069 (20130101) A61M 2209/045 (20130101) Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking B65B 3/003 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11645590 | Ardulov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
| INVENTOR(S) | Victor Ardulov (Long Beach, California); Aruna Jammalamadaka (Camarillo, California); Tsai-Ching Lu (Thousand Oaks, California) |
| ABSTRACT | Described is a system for learning and predicting key phrases. The system learns based on a dataset of historical forecasting questions, their associated time-series data for a quantity of interest, and associated keyword sets. The system learns the optimal policy of actions to take given the associated keyword sets and the optimal set of keywords which are predictive of the quantity of interest. Given a new forecasting question, the system extracts an initial keyword set from a new forecasting question, which are perturbed to generate an optimal predictive key-phrase set. Key-phrase time-series data are extracted for the optimal predictive key-phrase set, which are used to generate a forecast of future values for a value of interest. The forecast can be used for a variety of purposes, such as advertising online. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 17/730957 |
| ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/907 (20190101) G06F 16/90335 (20190101) G06F 40/40 (20200101) G06F 40/166 (20200101) G06F 40/205 (20200101) G06F 40/284 (20200101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6289 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0202 (20130101) G06Q 30/0255 (20130101) G06Q 50/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11644057 | Sabo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Scott G. Sabo (Long Beach, California) |
| ABSTRACT | A release mechanism for releasably securing a releasable structure to a stationary structure, where the mechanism employs release balls that can re-secure the releasable structure to the stationary structure. The release mechanism includes a base portion having three rails extending radially outward from a center of the base portion, and a rotatable portion rotatably mounted to the base portion, where the rotatable portion has a cam indentation. The release balls are positioned between the base portion and the rotatable portion so that one of the release balls is ridable on each of the rails and all of the release balls are positioned within the cam indentation. The cam indentation is configured so that as the rotatable portion is rotated relative to the base portion the cam indentation causes and allows the release balls to move along the rails in unison with each other to hold and release the releasable structure. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/852852 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/222 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 21/02 (20130101) F16B 21/165 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 403/592 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11646734 | Marakov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander Marakov (Columbia, Maryland); Anthony Joseph Przybysz (Linthicum, Maryland); James R. Medford (Columbia, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Alexander Marakov (Columbia, Maryland); Anthony Joseph Przybysz (Linthicum, Maryland); James R. Medford (Columbia, Maryland) |
| ABSTRACT | Systems and methods are provided for resetting a qubit comprising a superconducting loop and a compound Josephson junction. A first bias flux is provided to the superconducting loop. A second bias flux is provided to the compound Josephson junction. Each of the first bias flux and the second bias flux are provided such that a given excited state of the qubit is near a top of a potential barrier associated with a potential of the qubit. A continuous microwave signal is generated having a frequency equal to a transition frequency between an other excited state of the qubit and the given excited state. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/745408 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 17/92 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 09, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230509.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page