FedInvent™ Patents
Patent Details for Tuesday, May 16, 2023
This page was updated on Tuesday, May 16, 2023 at 09:37 AM GMT
Department of Health and Human Services (HHS)
US 11647737 | Tsai et al. |
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FUNDED BY |
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APPLICANT(S) | APPLIED STEMCELL, INC. (Milpitas, California); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | ASC THERAPEUTICS INC. (Milpitas, California); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Ruby Yanru Tsai (San Jose, California); Jie Xu (Fairfax, Virginia); Yuqing Chen (Superior Township, Michigan); Jifeng Zhang (Ann Arbor, Michigan); Ling-Jie Kong (Union City, California) |
ABSTRACT | Provided is a genetically modified non-human mammal that comprises an anchor DNA sequence inserted at an endogenous locus of a secretory milk protein gene, wherein the anchor DNA sequence comprises a site-specific recombinase recognition site. Also provided is a genetically modified non-human mammal that comprises a transgene inserted at an endogenous locus of a secretory milk protein gene, wherein the transgene encodes a secretory protein and is operably linked to the endogenous promoter of said secretory milk protein gene, and wherein the transgene is flanked by a pair of site-specific recombinase resulting sites. The genetically modified non-human mammals provided can be used for producing the secreted recombinant protein encoded by the transgene from the milk produced by the genetically modified non-human mammals. |
FILED | Friday, December 29, 2017 |
APPL NO | 16/475127 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) Original (OR) Class A01K 2217/072 (20130101) A01K 2227/107 (20130101) A01K 2267/01 (20130101) Peptides C07K 14/4732 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11647915 | Fielden et al. |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | Samuel Fielden (Charlottesville, Virginia); Li Zhao (Charlottesville, Virginia); Max Wintermark (Charlottesville, Virginia); Craig H. Meyer (Charlottesville, Virginia) |
ABSTRACT | Aspects of the present disclosure relate to systems and methods for medical imaging that incorporate prior knowledge. Some aspects relate to incorporating prior knowledge using a non-local means filter. Some aspects relate to incorporating prior knowledge for improved perfusion imaging, such as those incorporating arterial spin labeling. |
FILED | Thursday, April 02, 2015 |
APPL NO | 14/677891 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0263 (20130101) Original (OR) Class A61B 6/5229 (20130101) A61B 2576/026 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11647959 | Sun et al. |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Duxin Sun (Ann Arbor, Michigan); Yogesh B. Gianchandani (Ann Arbor, Michigan); Tao Li (Ann Arbor, Michigan); Jinhui Liao (Ann Arbor, Michigan); Qisen Cheng (Ann Arbor, Michigan); Johnathan Lewis (Ann Arbor, Michigan); Ryan Meredith (Ann Arbor, Michigan); Jeremy Felton (Ann Arbor, Michigan) |
ABSTRACT | An ingestible electronic capsule for the collection of samples along a gastric intestinal tract and methods relating thereto are provided. The ingestible electronic capsule includes a housing and a cap that form an interior chamber. The cap includes a sampling port and one or more sample collection chambers are disposed within the interior chamber. A motor is also disposed within the interior chamber and is configured to rotate one of the cap and the one or more sample collection chambers so to align one or the one or more sample collection chambers and the sampling port of the cap so to allow for sample collection. A microcontroller is also disposed within the interior chamber and is in communication with at least the motor. The microcontroller is configured to control the selective alignment of the sampling port and one of the one or more sample collection chambers and induce gastric intestinal fluid sampling. |
FILED | Wednesday, January 02, 2019 |
APPL NO | 16/958165 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/036 (20130101) A61B 5/073 (20130101) A61B 5/4255 (20130101) A61B 5/6861 (20130101) Original (OR) Class A61B 5/14539 (20130101) A61B 10/0045 (20130101) A61B 2010/0061 (20130101) A61B 2560/0214 (20130101) A61B 2562/06 (20130101) A61B 2562/162 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648200 | Chilkoti et al. |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Ashutosh Chilkoti (Durham, North Carolina); Davoud Mozhdehi (Durham, North Carolina); Kelli M. Luginbuhl (Durham, North Carolina) |
ABSTRACT | Disclosed herein are conjugates including a fatty acid, a self-assembly domain, and a polypeptide, where the conjugates have phase transition behavior. Further disclosed are methods of using the conjugates to treat disease, methods of delivering an agent, and methods of preparing the conjugates. |
FILED | Friday, January 12, 2018 |
APPL NO | 16/477229 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 47/42 (20130101) Peptides C07K 14/78 (20130101) C07K 2319/033 (20130101) C07K 2319/90 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/1029 (20130101) C12N 2501/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) Enzymes C12Y 203/01097 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648209 | Cheng et al. |
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APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
INVENTOR(S) | Qiang Cheng (Dallas, Texas); Tuo Wei (Dallas, Texas); Daniel J. Siegwart (Dallas, Texas) |
ABSTRACT | The present disclosure provides compositions which shown preferential targeting or delivery of a nucleic acid composition to a particular organ. In some embodiments, the composition comprises a steroid or sterol, an ionizable cationic lipid, a phospholipid, a PEG lipid, and a permanently cationic lipid which may be used to deliver a nucleic acid. |
FILED | Tuesday, June 14, 2022 |
APPL NO | 17/839699 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) Original (OR) Class A61K 48/0033 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2320/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648210 | Cheng et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
INVENTOR(S) | Qiang Cheng (Dallas, Texas); Tuo Wei (Dallas, Texas); Daniel J. Siegwart (Dallas, Texas) |
ABSTRACT | The present disclosure provides compositions which shown preferential targeting or delivery of a nucleic acid composition to a particular organ. In some embodiments, the composition comprises a steroid or sterol, an ionizable cationic lipid, a phospholipid, a PEG lipid, and a permanently cationic lipid which may be used to deliver a nucleic acid. |
FILED | Sunday, September 04, 2022 |
APPL NO | 17/929704 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) Original (OR) Class A61K 48/0033 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2320/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648221 | Deng |
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FUNDED BY |
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APPLICANT(S) | Emory University (Atlanta, Georgia) |
ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
INVENTOR(S) | Xingming Deng (Atlanta, Georgia) |
ABSTRACT | In certain embodiments, this disclosure relates to KRAS agonists, pharmaceutical composition, and uses in managing cancer. In certain embodiments, the KRAS agonist is 4-(4-(2-bromoacetamido)butyl)benzoic acid, salt, prodrug, or derivative thereof. In certain embodiments, this disclosure relates to methods of treating cancer comprising administering an effective amount of a compound of Formula I, salt, prodrug, or derivative thereof, to a subject in need thereof, wherein, substituents are reported herein. |
FILED | Monday, September 28, 2020 |
APPL NO | 17/034908 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648222 | Ghiaur et al. |
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FUNDED BY |
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APPLICANT(S) | Io Therapeutics, Inc. (Houston, Texas); The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | IO Therapeutics, Inc. (Spring, Texas); The Johns Hopkins Univercity (Baltimore, Maryland) |
INVENTOR(S) | Gabriel Ghiaur (Baltimore, Maryland); Richard J. Jones (Baltimore, Maryland); Salvador Alonso (Baltimore, Maryland); Roshantha A. Chandraratna (San Juan Capistrano, California) |
ABSTRACT | Disclosed herein are methods for treating a cancer comprising administering to a subject in need thereof an effective dose of a CYP26-resistant retinoic acid receptor (RAR) alpha (RARα) selective agonist, whereby as a result of the treatment the tumor burden is reduced in the subject and cancer stem cells resident in the bone marrow are substantially reduced. |
FILED | Tuesday, December 29, 2020 |
APPL NO | 17/136428 |
ART UNIT | 1628 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/58 (20130101) A61K 31/69 (20130101) A61K 31/138 (20130101) A61K 31/138 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) Original (OR) Class A61K 31/196 (20130101) A61K 31/277 (20130101) A61K 31/277 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/4166 (20130101) A61K 31/4166 (20130101) A61K 31/4196 (20130101) A61K 31/4196 (20130101) A61K 31/4545 (20130101) A61K 31/4545 (20130101) A61K 31/5685 (20130101) A61K 31/5685 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648237 | Baraban |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Scott C. Baraban (Novato, California) |
ABSTRACT | Provided, inter alia, are methods for treating an epilepsy disorder using a 5HT receptor agonist, or a pharmaceutically acceptable salt thereof. |
FILED | Friday, November 08, 2019 |
APPL NO | 16/679112 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/137 (20130101) A61K 31/137 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/4184 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648241 | Abergel et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Rebecca J. Abergel (Kensington, California); Taylor A. Choi (South San Francisco, California); Kenneth N. Raymond (Berkeley, California); David K. Shuh (Oakland, California) |
ABSTRACT | Provided herein are pharmaceutical formularions comprising a 1,2-HOPO chelating agent and/or 3,2-HOPO chelating agent. |
FILED | Tuesday, September 05, 2017 |
APPL NO | 16/330601 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0056 (20130101) A61K 9/0095 (20130101) A61K 9/1611 (20130101) A61K 9/1623 (20130101) A61K 9/1652 (20130101) A61K 9/2009 (20130101) A61K 9/2018 (20130101) A61K 9/2054 (20130101) A61K 31/444 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/04 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648272 | Georgiou et al. |
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APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | George Georgiou (Austin, Texas); Everett Stone (Austin, Texas); John Blazeck (Austin, Texas); Christos Karamitros (Austin, Texas) |
ABSTRACT | Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids. |
FILED | Tuesday, April 16, 2019 |
APPL NO | 16/385562 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/46 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) Enzymes C12Y 307/01003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648294 | Aldhamen et al. |
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APPLICANT(S) | Yasser A. Aldhamen (East Lansing, Michigan); Andrea Amalfitano (East Lansing, Michigan) |
ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
INVENTOR(S) | Yasser A. Aldhamen (East Lansing, Michigan); Andrea Amalfitano (East Lansing, Michigan) |
ABSTRACT | The present invention relates to compositions and methods for modulating immune responses using at least one CRACC composition comprising an adenoviral vector comprising at least one CRACC fusion. Such CRACC compositions may be combined with a number of other therapeutic agents which target modulating immune responses, as well as, treatments that include immune events. |
FILED | Wednesday, September 18, 2019 |
APPL NO | 16/574397 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/10343 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648297 | Lux et al. |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Jacques Lux (Dallas, Texas); Robert F. Mattrey (Dallas, Texas); Annie Y. Heble (Dallas, Texas) |
ABSTRACT | Shielding enzymes are made by modifying the enzyme surface with silica precursors and then depositing silica to a desired thickness while retaining biological activity of the enzyme. |
FILED | Sunday, June 02, 2019 |
APPL NO | 16/429026 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/44 (20130101) A61K 38/50 (20130101) A61K 38/51 (20130101) A61K 38/446 (20130101) Original (OR) Class A61K 38/4813 (20130101) A61K 49/221 (20130101) A61K 49/222 (20130101) A61K 49/223 (20130101) A61K 49/225 (20130101) A61K 51/088 (20130101) A61K 51/1244 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0065 (20130101) C12N 9/96 (20130101) C12N 11/14 (20130101) Enzymes C12Y 111/01006 (20130101) C12Y 113/12005 (20130101) C12Y 115/01001 (20130101) C12Y 304/17011 (20130101) C12Y 305/01001 (20130101) C12Y 404/01011 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648301 | Strober et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Samuel Strober (Stanford, California); Alexander Filatenkov (Menlo Park, California) |
ABSTRACT | In one aspect, the present invention provides a method for treating cancer comprising tumor cell vaccination in combination with hematopoietic and immune cell transplantation. In some embodiments, the method involves autologous tumor cell vaccination prior to autologous hematopoietic and immune cell transplantation. In another aspect, the present invention provides a method of purifying tumor cells from a subject in preparation for vaccination. |
FILED | Thursday, March 21, 2019 |
APPL NO | 16/360678 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) A61K 35/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 41/00 (20130101) A61K 2039/80 (20180801) A61K 2039/5152 (20130101) A61K 2039/55522 (20130101) A61K 2039/55561 (20130101) A61K 2300/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648304 | Livengood et al. |
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FUNDED BY |
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APPLICANT(S) | TAKEDA VACCINES, INC. (Cambridge, Massachusetts); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
ASSIGNEE(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Jill A. Livengood (Cambridge, Massachusetts); Holli Giebler (Cambridge, Massachusetts); Whitney Baldwin (Cambridge, Massachusetts); Hansi Dean (Cambridge, Massachusetts); Claire Y. H. Kinney (Atlanta, Georgia) |
ABSTRACT | The present disclosure relates to Zika virus vaccines and immunogenic compositions having one or more antigens from a Zika virus (e.g., a Zika virus clonal isolate, a non-human cell adapted Zika virus, etc.), and methods of manufacture, formulation, testing, and uses thereof. |
FILED | Monday, November 05, 2018 |
APPL NO | 16/761368 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/54 (20130101) A61K 2039/545 (20130101) A61K 2039/5252 (20130101) A61K 2039/55505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/24034 (20130101) C12N 2770/24071 (20130101) C12N 2770/24134 (20130101) C12N 2770/24151 (20130101) C12N 2770/24163 (20130101) C12N 2770/24164 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648307 | Ariizumi et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
INVENTOR(S) | Kiyoshi Ariizumi (Dallas, Texas); Ponciano Cruz (Dallas, Texas) |
ABSTRACT | The present disclosure is directed to antibodies that bind to DC-HIL on the surface of myeloid-derived suppressor cells, and thus antagonize the T cell suppressor function of these cells, as well as their use in diagnosing and treating cancers such as melanoma. |
FILED | Tuesday, December 31, 2019 |
APPL NO | 16/731285 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 39/395 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) Peptides C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2827 (20130101) C07K 2317/76 (20130101) C07K 2319/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6886 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5743 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648381 | Langer et al. |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Robert S. Langer (Newton, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts); Sahab I Babaee (Arlington, Massachusetts); Simo Pajovic (Mississauga, Canada); Jiuyun | Shi (Chicago, Illinois) |
ABSTRACT | Residence devices for long term delivery of therapeutic compounds and/or for sensing one or more relevant parameters in vivo are disclosed. In one embodiment, a residence device may include a plurality of links interconnected by a corresponding plurality of flexible hinges to permit the residence device to be deformed into a contracted configuration and subsequently permitted to return to an expanded configuration once positioned in a desired location, such as the stomach, of a subject. In some instances, at least a portion of the interconnected links may include a first link segment, a second link segment, and a coupling that selectively connects the first link segment to the second link segment. The coupling may be configured to weaken or decouple a connection between the first link segment and the second link segment when exposed to a temperature greater than a threshold temperature to selectively weaken and/or disassemble the residence device. |
FILED | Friday, November 15, 2019 |
APPL NO | 16/684638 |
ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/16 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14276 (20130101) A61M 31/002 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648394 | Frank et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Loren M. Frank (San Anselmo, California); Jason Chung (Oakland, California) |
ABSTRACT | The present disclosure generally provides methods of implanting an implantable device in contact with a brain of a subject. Also provided are kits and systems for the implantation of one or more implantable devices. |
FILED | Friday, November 02, 2018 |
APPL NO | 16/756013 |
ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/6868 (20130101) A61B 17/3468 (20130101) A61B 2090/103 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) Original (OR) Class A61N 1/0539 (20130101) A61N 1/37223 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648559 | Mao |
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FUNDED BY |
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APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
INVENTOR(S) | Leidong Mao (Athens, Georgia) |
ABSTRACT | A variety of devices and methods are provided for separating or enriching circulating tumor cells in a biological sample such as whole blood. In some aspects, the devices are multi-stage devices including at least (i) a filtering stage, (ii) a sheath flow stage for ferrohydrodynamic separation of magnetically labelled white blood cells, and (iii) a focusing stage for marker-independent and size-independent focusing of magnetically labeled particles so as to separate or enrich unlabeled rare cells in the biological sample. The devices and methods are, in some aspects, capable of high throughput in excess of 6 milliliters per hour while achieving high separation (>95%) of the unlabeled rare cells. |
FILED | Saturday, August 04, 2018 |
APPL NO | 16/636517 |
ART UNIT | 3653 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 3/502776 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/0681 (20130101) B01L 2300/0864 (20130101) B01L 2300/0883 (20130101) B01L 2400/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649214 | Capobianco et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
INVENTOR(S) | Anthony J. Capobianco (Miami Beach, Florida); Stephan C. Schürer (Coral Gables, Florida); Xiaoxia Zhu (Palmetto Bay, Florida); Tanya T. Kelley (Miami, Florida) |
ABSTRACT | Disclosed herein are Notch transcriptional activation complex kinase (“NACK”) inhibitors, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein include compounds of Formula (la) and pharmaceutically acceptable salts thereof: wherein the substituents are as described. |
FILED | Wednesday, February 06, 2019 |
APPL NO | 16/967652 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 231/54 (20130101) Original (OR) Class Enzymes C12Y 207/00 (20130101) C12Y 306/01003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649218 | Marugan et al. |
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FUNDED BY |
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APPLICANT(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); Pontificia Universidad Católica de Chile (Santiago, Chile) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Pontificia Universidad Catolica de Chile (Santiago, Chile) |
INVENTOR(S) | Juan J. Marugan (Gaithersburg, Maryland); Marc Ferrer (Potomac, Maryland); Noel T. Southall (Potomac, Maryland); Andres E. Dulcey (Gaithersburg, Maryland); Xin Hu (Frederick, Maryland); Christopher R. Dextras (Frederick, Maryland); Daniel C. Talley (Baltimore, Maryland); Alejandra Alvarez (Santiago, Chile); Silvana Zanlungo (Santiago, Chile); Rommy M. Von Bernhardi (Santiago, Chile) |
ABSTRACT | Disclosed herein are embodiments of a compound that inhibits c-Abl tyrosine kinase (also referred to herein as “c-Abl”). The compound embodiments described herein are novel c-Abl inhibitors that can bind to c-Abl at an allosteric site and inhibit its activity in various pathways. The compound embodiments also are capable of crossing the blood brain barrier and therefore are useful in inhibiting c-Abl activity as it affects pathways and/or proteins in the brain. The compound embodiments described herein are effective therapeutic agents for treating diseases involving c-Abl, such as cancers, motor neuron diseases, and neurodegenerative diseases. Also disclosed herein are embodiments of methods for making and using the c-Abl inhibitory compound embodiments. |
FILED | Friday, March 08, 2019 |
APPL NO | 16/976012 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/553 (20130101) A61K 31/554 (20130101) A61K 31/5513 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) A61P 25/28 (20180101) A61P 33/06 (20180101) A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 201/12 (20130101) C07C 227/22 (20130101) C07C 319/14 (20130101) Heterocyclic Compounds C07D 243/38 (20130101) Original (OR) Class C07D 267/18 (20130101) C07D 267/20 (20130101) C07D 281/16 (20130101) C07D 401/04 (20130101) C07D 403/04 (20130101) C07D 413/04 (20130101) C07D 413/10 (20130101) C07D 413/14 (20130101) C07D 417/04 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) C07F 7/0812 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649228 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
INVENTOR(S) | Wen-Hong Li (Dallas, Texas); Ebrahim Ghazvini Zadeh (Dallas, Texas) |
ABSTRACT | The present disclosure provides compounds of the formula: wherein the variables are defined herein. The present disclosure also provides methods of imaging Zn2+ within granules in cells, such as pancreatic α-, β-, and δ-cells. The present disclosure also provides methods of sorting cells comprising the use of the compounds of the present disclosure. |
FILED | Monday, October 28, 2019 |
APPL NO | 16/665647 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 405/14 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/06 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/54 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 21/76 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649234 | Miller et al. |
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FUNDED BY |
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APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
ASSIGNEE(S) | THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
INVENTOR(S) | Courtney Miller (Jupiter, Florida); Patrick R. Griffin (Jupiter, Florida); Theodore Mark Kamenecka (Palm Beach Gardens, Florida); Gavin Rumbaugh (Jupiter, Florida); Matthew Surman (Albany, New York); Steve Young (Lansdale, Pennsylvania); Steven Duddy (Ann Arbor, Michigan); Laszlo Radnai (East Palm Beach Gardens, Florida) |
ABSTRACT | The invention can provide compounds, analogs of blebbistatin, effective and selective inhibitors of nonmuscle myosin II relative to cardiac myosin II. Compounds can be used in the method of treating a disease, disorder, or medical condition in a patient, comprising modulating myosin II ATPase, such as treatment of substance abuse relapse disorder, or of renal disease, cancer and metastasis, benign prostate hyperplasia, hemostasis or thrombosis, nerve injury including retinal damage, lung fibrosis, liver fibrosis, arthrofibrosis, wound healing, spinal cord injury, periodontitis, glaucoma and immune-related diseases including multiple sclerosis; or wherein the disease, disorder, or medical condition comprises addiction including abuse of or addiction to anything classified as a Substance-Related or Addictive Disorder in the Diagnostic and Statistical Manual of Mental Disorders (DSM), such as, but not limited to, cocaine, opioids, amphetamines, ethanol, cannabis/marijuana, nicotine, and activities including gambling Compounds are of general formula (I) with substituents as defined herein. |
FILED | Thursday, June 13, 2019 |
APPL NO | 17/250203 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 471/14 (20130101) C07D 495/14 (20130101) C07D 519/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649237 | Keenan et al. |
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FUNDED BY |
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APPLICANT(S) | Optikira LLC (Cleveland, Ohio); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | Optikira LLC (Cleveland, Ohio); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Richard M. Keenan (Malvern, Pennsylvania); Bradley J. Backes (San Francisco, California); Dustin J. Maly (Seattle, Washington); Charles Reynolds (Malvern, Pennsylvania); Ben Whittaker (Malvern, Pennsylvania); Jamie Knight (Malvern, Pennsylvania); Jonathan Mark Sutton (Malvern, Pennsylvania); George Hynd (Malvern, Pennsylvania); Feroz R. Papa (Oakland, California); Scott A. Oakes (Oakland, California) |
ABSTRACT | Provided herein, inter alia, are substituted imidazo[1,5-α]pyrazine compounds, compositions and methods for treating or preventing an IRE1α-related disease or disorder. In certain embodiments, the disease or disorder is selected from the group consisting of a neurodegenerative disease, a demyelinating disease, cancer, an eye disease, a fibrotic disease, and diabetes. |
FILED | Friday, August 31, 2018 |
APPL NO | 16/642208 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 519/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649240 | Petrukhin et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Konstantin Petrukhin (New Windsor, New York); Christopher Cioffi (Troy, New York); Graham Johnson (Sanbornton, New Hampshire); Rando Allikmets (Cornwall on Hudson, New York); Emily Freeman (Voorheesville, New York); Ping Chen (Slingerlands, New York); Michael Conlon (Schenectady, New York); Lei Zhu (Glenmont, New York) |
ABSTRACT | The present invention provides a compound having the structure: wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl, wherein two or more of R1, R2, R3, R4, or R5 are other than H; R6 is H, OH, or halogen; and B is a substituted or unsubstituted heterobicycle, wherein when R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is H, R2 is CF3, R3 is H, R4 is CF3, and R5 is H, or R1 is Cl, R2 is H, R3 is H, R4 is F, and R5 is H, or R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is CF3, R2 is F, R3 is H, R4 is H, and R5 is H, or R1 is Cl, R2 is F, R3 is H, R4 is H, and R5 is H, then B is other than or a pharmaceutically acceptable salt thereof. |
FILED | Monday, November 16, 2020 |
APPL NO | 17/099231 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) C07D 487/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649276 | Mouquet et al. |
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FUNDED BY |
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APPLICANT(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Hugo Mouquet (New York, New York); Michel Nussenzweig (New York, New York); Pamela J. Bjorkman (La Canada Flintridge, California); Louise Scharf (Porter Ranch, California) |
ABSTRACT | The present invention relates to anti-HIV antibodies. Also disclosed are related methods and compositions. HIV causes acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies. Since its discovery in 1981, HIV type 1 (HIV-1) has led to the death of at least 25 million people worldwide. |
FILED | Thursday, September 09, 2021 |
APPL NO | 17/470184 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/1045 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/21 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/64 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16111 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649279 | Rosenthal et al. |
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FUNDED BY |
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APPLICANT(S) | Annexon, Inc. (South San Francisco, California) |
ASSIGNEE(S) | Annexon, Inc. (South San Francisco, California) |
INVENTOR(S) | Arnon Rosenthal (Woodside, California); Michael Leviten (Emerald Hills, California) |
ABSTRACT | The present invention provides anti-C1q antibodies and methods of using the same. |
FILED | Wednesday, February 10, 2021 |
APPL NO | 17/172807 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0004 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/40 (20130101) C07K 2317/14 (20130101) C07K 2317/20 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/734 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 2333/4716 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649284 | Gottschalk et al. |
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FUNDED BY |
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APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
INVENTOR(S) | Stephen M. G. Gottschalk (Houston, Texas); Felicia Cao (Houston, Texas) |
ABSTRACT | Embodiments of the disclosure concern treatment of cancer utilizing methods and compositions that block CD47 such that tumor associated macrophages (TAMs) are not inhibited by CD47 and are able to phagocytose and kill tumor cells. In specific embodiments, the compositions and their use concern fusions of an entity that binds CD47 and an entity that binds cells having FC receptors, such as the FC receptor on TAMs. Certain embodiments concern gene therapy that produces a fusion of the ectodomain of SIRPa and the constant region of IgG4 at a localized tumor or tumor microenvironment, for example. In specific cases, gene transfer is utilized to deliver SIRPa fusion genes into a tumor and/or tumor microenvironment so that the molecules can be expressed locally to increase efficacy (given that the expression of the molecules will be highest at tumor sites) and decrease potential toxicities. |
FILED | Tuesday, April 18, 2017 |
APPL NO | 16/094416 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 48/005 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/705 (20130101) C07K 14/70596 (20130101) C07K 16/283 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 2317/622 (20130101) C07K 2319/30 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649287 | Diaz et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Luis Diaz (Ellicot City, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland); Dung Le (Lutherville, Maryland); Drew M. Pardoll (Brookville, Maryland); Suzanne L. Topalian (Brookville, Maryland) |
ABSTRACT | Blockade of immune checkpoints such as cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed death-1 (PD-1) shows promise in patients with cancer. Inhibitory antibodies directed at these receptors have been shown to break immune tolerance and promote anti-tumor immunity. These agents work particularly well in patients with a certain category of tumor. Such tumors may be particularly susceptible to treatment because of the multitude of neoantigens which they produce. |
FILED | Thursday, September 02, 2021 |
APPL NO | 17/465096 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/55 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/30 (20130101) C07K 16/40 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/00 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 113/11052 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649291 | Griswold et al. |
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FUNDED BY |
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APPLICANT(S) | Insmed Incorporated (Bridgewater, New Jersey) |
ASSIGNEE(S) | Insmed Incorporated (Bridgewater, New Jersey) |
INVENTOR(S) | Karl Edwin Griswold (Lyme, New Hampshire); Chris Bailey-Kellogg (Strafford, Vermont); Yoonjoo Choi (Gyeonggi-do, South Korea) |
ABSTRACT | Provided are variants of a chimeric anti-EGFR antibody. In various embodiments, the variants exhibit substantially improved thermostabilities and/or substantially higher levels of humanness, while retaining binding affinity near the parental level. The consistently high quality of the turnkey CoDAH designs, over a whole panel of variants, suggests that a computationally-directed approach encapsulates key determinants of antibody structure and function. |
FILED | Wednesday, May 24, 2017 |
APPL NO | 16/303530 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Peptides C07K 16/2863 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649326 | Luo et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
ASSIGNEE(S) | The Research Foundation for the State University of New York (Syracuse, New York) |
INVENTOR(S) | Juntao Luo (Syracuse, New York); Xu Wang (Syracuse, New York); Changying Shi (Jamesville, New York) |
ABSTRACT | Provided are multiply functional charged telodendrimers. The telodendrimers can be used for protein encapsulation and delivery. The charged telodendrimers may have one or more crosslinking groups (e.g., boronic acid/catechol reversible crosslinking groups). The telodendrimers can aggregate to form nanoparticles. Cargo such as combinations of proteins and other materials may be sequestered in the core of the nanoparticles via non-covalent or covalent interactions with the telodendrimers. Such nanoparticles may be used in protein delivery applications. |
FILED | Tuesday, March 02, 2021 |
APPL NO | 17/189868 |
ART UNIT | 1699 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/107 (20130101) A61K 9/5146 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/08 (20180101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/329 (20130101) C08G 83/00 (20130101) C08G 83/002 (20130101) Original (OR) Class C08G 2650/32 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649424 | Vunjak-Novakovic et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Gordana Vunjak-Novakovic (New York, New York); Hesam Parsa (New York, New York) |
ABSTRACT | The present disclosure relates to a pneumatic microfluidic platform for high-throughput studies of cardiac hypertrophy that enables repetitive (hundreds of thousands of times) and robust (over several weeks) manipulation of cardiac μtissues. The platform is reusable for stable and reproducible mechanical stimulation of cardiac μtissues (each containing only 500 cells). Heterotypic and homotypic μtissues produced in the device were pneumatically loaded in a range of regimes, with real-time on-chip analysis of tissue phenotypes. Concentrated loading of the three-dimensional cardiac tissue faithfully recapitulated the pathology of volume overload seen in native heart tissue. Sustained volume overload of μtissues was sufficient to induce pathological cardiac remodeling associated with upregulation of the fetal gene program, in a dose-dependent manner. |
FILED | Tuesday, July 24, 2018 |
APPL NO | 16/043877 |
ART UNIT | 1799 — Organic Chemistry |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 23/12 (20130101) C12M 23/16 (20130101) C12M 35/04 (20130101) C12M 41/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649430 | Keller |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Nancy P. Keller (Madison, Wisconsin) |
ABSTRACT | A method of promoting fungal spore germination. The method includes the step of contacting a fungal spore with a germination-promoting concentration of an exogenous imizoquin. |
FILED | Monday, August 26, 2019 |
APPL NO | 16/550720 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/90 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/38 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649431 | Studer et al. |
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FUNDED BY |
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APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); CORNELL UNIVERSITY (Ithaca, New York) |
ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); CORNELL UNIVERSITY (Ithaca, New York) |
INVENTOR(S) | Lorenz Studer (New York, New York); Asif M. Maroof (Bowie, Massachusetts); Stewart Anderson (Philadelphia, Pennsylvania) |
ABSTRACT | Provided are cortical interneurons and other neuronal cells and in vitro methods for producing such cortical interneurons and other neuronal cells by the directed differentiation of stem cells and neuronal progenitor cells. The present disclosure relates to novel methods of in vitro differentiation of stem cells and neural progenitor cells to produce several type neuronal cells and their precursor cells, including cortical interneurons, hypothalamic neurons and pre-optic cholinergic neurons. The present disclose describes the derivation of these cells via inhibiting SMAD and Wnt signaling pathways and activating SHH signaling pathway. The present disclosure relates to the novel discovery that the timing and duration of SHH activation can be harnessed to direct controlled differentiation of neural progenitor cells into either cortical interneurons, hypothalamic neurons or pre-optic cholinergic neurons. The present disclosure also relates to compositions of cortical interneurons, hypothalamic neurons or pre-optic cholinergic neurons, and their precursors, that are highly enriched and can be used in variety of application. These cells can be used therapeutically to treat neurodegenerative and neuropsychiatric disorders, and can be used for disease modeling and drug screening. |
FILED | Friday, October 23, 2015 |
APPL NO | 14/922110 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 2501/15 (20130101) C12N 2501/41 (20130101) C12N 2501/415 (20130101) C12N 2501/999 (20130101) C12N 2502/08 (20130101) C12N 2506/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5029 (20130101) G01N 33/5058 (20130101) G01N 33/5073 (20130101) G01N 33/5088 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
11649435 — Methods and compositions for cells expressing a chimeric intracellular signaling molecule
US 11649435 | June et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Wayne State University (Detroit, Michigan) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Wayne State University (Detroit, Michigan) |
INVENTOR(S) | Carl H. June (Merion Station, Pennsylvania); Michael Milone (Cherry Hill, New Jersey); Yangbing Zhao (Lumberton, New Jersey); Lawrence G. Lum (Charlottesville, Virginia); Archana Thakur (Charlottesville, Virginia) |
ABSTRACT | The present invention relates to compositions and methods for enhancing T cell metabolism and activity for more effective adoptive T cell therapy. By expressing an intracellular signaling molecule in T cells, the T cells are metabolically enhanced with improved cytotoxicity and resistance to immunosuppression imposed by tumor microenvironments. One aspect includes a modified T cell and pharmaceutical compositions comprising the modified cells for adoptive cell therapy and treating a disease or condition associated with enhanced immunity. |
FILED | Thursday, August 25, 2016 |
APPL NO | 15/756244 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/4748 (20130101) C07K 14/7051 (20130101) C07K 16/32 (20130101) C07K 16/2863 (20130101) C07K 16/2887 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2510/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649437 | Bollard et al. |
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FUNDED BY |
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APPLICANT(S) | CHILDREN'S NATIONAL MEDICAL CENTER (Washington, District of Columbia) |
ASSIGNEE(S) | CHILDREN'S NATIONAL MEDICAL CENTER (Washington, District of Columbia) |
INVENTOR(S) | Catherine M. Bollard (Washington, District of Columbia); Conrad Russell Cruz (Washington, District of Columbia); Patrick J. Hanley (Washington, District of Columbia); Michael Keller (Washington, District of Columbia) |
ABSTRACT | Safe, rapid and efficient methods for producing antigen-specific T cells recognizing human papilloma virus or HPV antigens. |
FILED | Tuesday, January 19, 2021 |
APPL NO | 17/152149 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/00 (20180101) A61P 31/00 (20180101) A61P 37/04 (20180101) Peptides C07K 14/55 (20130101) C07K 14/5412 (20130101) C07K 14/5418 (20130101) C07K 14/5434 (20130101) C07K 14/5443 (20130101) C07K 14/70514 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/59 (20130101) C12N 2501/2302 (20130101) C12N 2501/2307 (20130101) C12N 2501/2315 (20130101) C12N 2502/1121 (20130101) C12N 2502/1157 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649447 | You et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Lingchong You (Durham, North Carolina); Anna Lee (Durham, North Carolina); Zhuojun Dai (Durham, North Carolina) |
ABSTRACT | The present disclosure relates to compositions, systems, and methods for the production of biomolecules using microorganisms. In particular, the present disclosure provides biomolecule production platforms that include genetically engineered microorganisms with genetic circuits functionally coupled to microcapsules formed from materials that are responsive to culture conditions. The biomolecule production platforms disclosed herein facilitate the efficient and robust production, purification, and/or analysis of any biomolecule-of-interest. |
FILED | Tuesday, June 12, 2018 |
APPL NO | 16/621615 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 25/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) Original (OR) Class C12N 15/70 (20130101) C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649451 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Zhen Chen (Boston, Massachusetts); Phillip Andrew Lichtor (Cambridge, Massachusetts) |
ABSTRACT | The present invention provides methods and compositions for performing ordered multi-step syntheses involving modified nucleic acids by nucleic acid-mediated chemistry. This approach is useful for generating sequence-defined highly functionalized nucleic acid polymers. The invention also provides modified nucleic acid polymers that bind to proteins of interest (e.g., PCSK9 and IL-6), which are implicated in human disease. |
FILED | Friday, July 06, 2018 |
APPL NO | 16/629013 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7115 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1068 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649457 | Pyle et al. |
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FUNDED BY |
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APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
INVENTOR(S) | Anna Marie Pyle (Guilford, Connecticut); Akiko Iwasaki (Guilford, Connecticut); Tianyang Mao (New Haven, Connecticut) |
ABSTRACT | The present disclosure provides small hairpin nucleic acid molecules capable of stimulating interferon production. The nucleic acid molecules of the present disclosure has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises at least one 5′-triphosphate and/or at least one 5′-diphosphate. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection, and/or ameliorating, minimizing, reversing, and/or preventing persistent SARS-CoV-2 viral infection, and/or minimizing or preventing SARS-CoV-2 viral infection-derived mortality and/or lethality, in a subject. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection in a tumor-bearing subject. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection in an immune-compromised and/or immunodeficient subject. |
FILED | Wednesday, March 30, 2022 |
APPL NO | 17/709282 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649458 | Daugherty et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky) |
ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
INVENTOR(S) | Alan Daugherty (Lexington, Kentucky); Hong Lu (Lexington, Kentucky); Mary Sheppard (Lexington, Kentucky); Jeff Chen (Lexington, Kentucky) |
ABSTRACT | Disclosed herein is a method for attenuating aortic pathology in a subject having Marfan syndrome by reducing angiotensinogen plasma levels in the subject. |
FILED | Wednesday, May 05, 2021 |
APPL NO | 17/308895 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4178 (20130101) A61K 31/7088 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/351 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649462 | Farhadi et al. |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Arash Farhadi (Pasadena, California); Gabrielle H Ho (Pasadena, California); Daniel P Sawyer (Pasadena, California); Mikhail Shapiro (Pasadena, California); Robert C. Hurt (Pasadena, California); Mengtong Duan (Pasadena, California) |
ABSTRACT | Provided herein are genetically engineered gas vesicle expression systems (GVES) that are configured to express gas vesicles (GVs) in a mammalian cell, related gas vesicle polynucleotide constructs, gas vesicle reporting genetic circuits, vectors, genetically engineered mammalian cells, non-human mammalian hosts, compositions, methods and systems, which in several embodiments can be used together with contrast-enhanced imaging techniques to detect and report biological events in an imaging target site comprising a mammalian cell and/or organism. |
FILED | Tuesday, January 07, 2020 |
APPL NO | 16/736683 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Original (OR) Class C12N 2510/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649464 | Slade et al. |
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FUNDED BY |
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APPLICANT(S) | Arcadia Biosciences, Inc. (Davis, California) |
ASSIGNEE(S) | ARCADIA BIOSCIENCES, INC. (Davis, California) |
INVENTOR(S) | Ann J. Slade (Bellevue, Washington); Dayna L. Loeffler (Seattle, Washington); Aaron M. Holm (Shoreline, Washington); Jessica C. Mullenberg (Lynnwood, Washington) |
ABSTRACT | A series of independent human-induced non-transgenic mutations found at one or more of the SBEII genes of wheat; wheat plants having these mutations in one or more of their SBEII genes; and a method of creating and finding similar and/or additional mutations of SBEII by screening pooled and/or individual wheat plants. The seeds and flour from the wheat plants of the present invention exhibit an increase in amylose and resistant starch without having the inclusion of foreign nucleic acids in their genomes. Additionally, the wheat plants of the present invention exhibit altered SBEII activity without having the inclusion of foreign nucleic acids in their genomes. |
FILED | Tuesday, January 12, 2021 |
APPL NO | 17/147281 |
ART UNIT | 1662 — Plants |
CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/4678 (20180501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/107 (20130101) C12N 15/8245 (20130101) Original (OR) Class Enzymes C12Y 204/01018 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649469 | Church et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | George M. Church (Brookline, Massachusetts); Kevin M. Esvelt (Auburndale, Massachusetts); Prashant G. Mali (La Jolla, California) |
ABSTRACT | Methods of modulating expression of a target nucleic acid in a cell are provided including use of multiple orthogonal Cas9 proteins to simultaneously and independently regulate corresponding genes or simultaneously and independently edit corresponding genes. |
FILED | Tuesday, May 14, 2019 |
APPL NO | 16/411793 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 2/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/85 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/3519 (20130101) C12N 2320/33 (20130101) C12N 2320/50 (20130101) C12N 2800/40 (20130101) C12N 2800/80 (20130101) C12N 2800/107 (20130101) C12N 2810/10 (20130101) C12N 2830/00 (20130101) C12N 2830/34 (20130101) C12N 2999/007 (20130101) Enzymes C12Y 301/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649482 | Bell et al. |
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FUNDED BY |
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APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Avery Davis Bell (Cambridge, Massachusetts); Steven A. McCarroll (Cambridge, Massachusetts) |
ABSTRACT | The present disclosure relates to compositions and methods for performing droplet-based high throughput sequencing upon genomic DNA of single cells (e.g., individual sperm). The instant disclosure provides a droplet that includes: i) a mammalian cell nucleus; and ii) a microbead presenting attached oligonucleotides, where the attached oligonucleotides include a nucleic acid sequence capable of hybridization and capture of genomic DNA and a microbead identification sequence that is common to all oligonucleotides attached to the microbead, where the mammalian cell nucleus is accessible to the microbead-attached oligonucleotides to an extent sufficient to allow for genomic DNA capture and amplification of genomic DNA to occur within the droplet. |
FILED | Friday, April 26, 2019 |
APPL NO | 17/053418 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649484 | Bowler et al. |
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FUNDED BY |
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APPLICANT(S) | ABBOTT DIAGNOSTICS SCARBOROUGH, INC. (Scarborough, Maine) |
ASSIGNEE(S) | ABBOTT DIAGNOSTICS SCARBOROUGH, INC. (Scarborough, Maine) |
INVENTOR(S) | Frank Ray Bowler (Norfolk, United Kingdom); Grzegorz Artur Orlowski (Cambridgeshire, United Kingdom); Hazel Lucy Greetham (Cambridgeshire, United Kingdom); Cheng Zhou (Cambridgeshire, United Kingdom); Niall A. Armes (Suffolk, United Kingdom); Olaf Piepenburg (Essex, United Kingdom) |
ABSTRACT | This invention relates to sequence specific electrochemically-labeled oligonucleotide probes for the detection of nucleic acids and methods associated therewith. |
FILED | Friday, February 24, 2017 |
APPL NO | 16/079273 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6876 (20130101) C12Q 2525/186 (20130101) C12Q 2563/113 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649503 | Schwartz et al. |
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FUNDED BY |
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APPLICANT(S) | National Jewish Health (Denver, Colorado) |
ASSIGNEE(S) | National Jewish Health (Denver, Colorado) |
INVENTOR(S) | David A. Schwartz (Aurora, Colorado); Max Seibold (Denver, Colorado) |
ABSTRACT | The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease. |
FILED | Friday, November 06, 2020 |
APPL NO | 17/091507 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/172 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/4725 (20130101) G01N 2800/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651850 | Ward et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Kevin Ward (Glen Allen, Virginia); Daniel Francis Taylor (Belleville, Michigan); Michael W. Sjoding (Ann Arbor, Michigan); Christopher Elliot Gillies (Ann Arbor, Michigan) |
ABSTRACT | A computer-implemented method includes preprocessing a variable dimension medical image, identifying one or more areas of interest in the medical image; and analyzing the one or more areas of interest using a deep learning model. A computing system includes one or more processors; and one or more memories storing instructions that, when executed by the one or more processors, cause the computing system to preprocess a variable dimension medical image, identify one or more areas of interest in the medical image; and analyze the one or more areas of interest using a deep learning model. A non-transitory computer readable medium contains program instructions that when executed, cause a computer to preprocess a variable dimension medical image, identify one or more areas of interest in the medical image, and analyze the one or more areas of interest using a deep learning model. |
FILED | Wednesday, October 28, 2020 |
APPL NO | 17/082145 |
ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 11/20 (20130101) G06T 2207/10116 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30061 (20130101) G06T 2210/12 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 11647904 | Hu et al. |
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FUNDED BY |
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APPLICANT(S) | University Of Maryland, Baltimore (Baltimore, Maryland) |
ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
INVENTOR(S) | Fu-Ming Hu (Ellicott City, Maryland); Lynn G. Stansbury (Seattle, Washington); Colin F. Mackenzie (Pasadena, Maryland); Thomas M. Scalea (Baltimore, Maryland); Deborah M. Stein (Owings Mills, Maryland); Shiming Yang (Halethorpe, Maryland) |
ABSTRACT | A method and apparatus for monitoring collection of subject condition data is provided. The method includes receiving a value of a parameter of subject condition data and a value of a sample time, for each of a plurality of sample times. The method also includes storing the subject condition data in a data structure including a first field for holding data indicating a current sample time and a second field for holding data indicating the value of the parameter. The method also includes determining a time gap defined by a duration between the current sample time and a most recent sample time and determining whether the time gap exceeds a time gap threshold and causing an apparatus to perform remedial action. A method for presenting the subject condition data on a display is also provided. |
FILED | Monday, February 21, 2022 |
APPL NO | 17/676657 |
ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0006 (20130101) A61B 5/0008 (20130101) A61B 5/0022 (20130101) Original (OR) Class A61B 5/1113 (20130101) A61B 5/1455 (20130101) A61B 5/02055 (20130101) A61B 5/02405 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 10/60 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648239 | Dobi et al. |
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FUNDED BY |
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APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
INVENTOR(S) | Albert L. Dobi (Rockville, Maryland); Clifton L. Dalgard (Chevy Chase, Maryland); Shiv K. Srivastava (Potomac, Maryland) |
ABSTRACT | Selective azophenol inhibitors of a wild type or an altered ERG protein expression are described, where the inhibitors represent a compound of Formula (I) or Formula (II) wherein X, X1, X2, X3, X4 and X5, R1 through R4 and R9 are as described. |
FILED | Tuesday, January 26, 2021 |
APPL NO | 17/158930 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/426 (20130101) Original (OR) Class A61K 31/4402 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 245/00 (20130101) C07C 245/02 (20130101) C07C 245/04 (20130101) Heterocyclic Compounds C07D 277/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648529 | McGill et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | R. Andrew McGill (Lorton, Virginia); Courtney A. Roberts (Washington, District of Columbia) |
ABSTRACT | The invention relates to strong hydrogen-bond acidic sorbents. The sorbents may be provided in a form that limits or eliminates intramolecular bonding of the hydrogen-bond acidic site between neighboring sorbent molecules, for example, by providing steric groups adjacent to the hydrogen-bond acidic site. The hydrogen bond site may be a phenolic structure based on a bisphenol architecture. The sorbents of the invention may be used in methods for trapping or detecting hazardous chemicals or explosives. |
FILED | Thursday, April 21, 2022 |
APPL NO | 17/725840 |
ART UNIT | 1796 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) Original (OR) Class B01J 20/281 (20130101) B01J 20/282 (20130101) B01J 20/3425 (20130101) B01J 20/3483 (20130101) B01J 20/28023 (20130101) B01J 2220/54 (20130101) Acyclic or Carbocyclic Compounds C07C 39/367 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 14/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/00 (20130101) C08G 64/00 (20130101) C08G 64/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/482 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648548 | Landers et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Chemical Biological Center (APG, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | John M. Landers (Riverton, New Jersey); Christopher J. Karwacki (Churchville, Maryland); Trenton M. Tovar (Parkville, Maryland); Gregory W. Peterson (Bel Air, Maryland) |
ABSTRACT | The present invention relates to single thread composite fibers comprising at least one binder and at least one active catalyst for the capture and degradation of chemical threats such as chemical warfare agents (CWA), biological warfare agents, and toxic industrial chemicals (TIC) and a method for producing the same. The invention fibers are applicable to the fields of protective garments, filtration materials, and decontamination materials. |
FILED | Friday, August 20, 2021 |
APPL NO | 17/407457 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/30 (20130101) A62D 2101/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/066 (20130101) B01J 35/06 (20130101) Original (OR) Class B01J 35/1004 (20130101) B01J 35/1052 (20130101) B01J 37/0009 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649042 | Dunn et al. |
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FUNDED BY |
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APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
ASSIGNEE(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
INVENTOR(S) | Eric Dunn (Trumbull, Connecticut); Keith M. Schenone (Fairfield, Connecticut); Sven R. Lofstrom (Irving, Texas) |
ABSTRACT | According to an aspect, a method of assembling a mandrel includes assembling a plurality of members via interlocking features arranged at opposing edges of each member of the plurality of members to form a compartment, the assembled members having a collective outer surface that conforms to an inner surface of the spar. A support member is inserted into the compartment formed radially inward from the assembled members, the support member making contact with a portion of each member of the plurality of members. |
FILED | Tuesday, July 14, 2020 |
APPL NO | 16/928453 |
ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/485 (20130101) B29C 53/824 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 99/0028 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Aeroplanes; Helicopters B64C 27/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649158 | Dosev et al. |
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FUNDED BY |
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APPLICANT(S) | Rosemount Aerospace Inc. (Burnsville, Minnesota) |
ASSIGNEE(S) | Rosemount Aerospace Inc. (Burnsville, Minnesota) |
INVENTOR(S) | Dosi Dosev (Chanhassen, Minnesota); David P. Potasek (Lakeville, Minnesota); Marcus Allen Childress (Farmington, Minnesota) |
ABSTRACT | A microelectromechanical systems (MEMS) device includes a MEMS device body connected to a first mooring portion and a second mooring portion. The MEMS device body further includes a first cantilever and a second cantilever and connected by a spring. The spring is in operable communication with the first cantilever and the second cantilever. |
FILED | Monday, July 22, 2019 |
APPL NO | 16/517944 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) Original (OR) Class B81B 2203/019 (20130101) B81B 2203/0118 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649159 | Kub et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | |
INVENTOR(S) | Francis J. Kub (Arnold, Maryland); Karl D. Hobart (Alexandria, Virginia); Eugene A. Imhoff (Washington, District of Columbia); Rachael L. Myers-Ward (Springfield, Virginia) |
ABSTRACT | A method of fabricating suspended beam silicon carbide microelectromechanical (MEMS) structure with low capacitance and good thermal expansion match. A suspended material structure is attached to an anchor material structure that is direct wafer bonded to a substrate. The anchor material structure and the suspended material structure are formed from either a hexagonal single-crystal SiC material, and the anchor material structure is bonded to the substrate while the suspended material structure does not have to be attached to the substrate. The substrate may be a semi-insulating or insulating SiC substrate. The substrate may have an etched recess region on the substrate first surface to facilitate the formation of the movable suspended material structures. The substrate may have patterned electrical electrodes on the substrate first surface, within recesses etched into the substrate. |
FILED | Monday, September 14, 2020 |
APPL NO | 17/020702 |
ART UNIT | 2811 — Semiconductors/Memory |
CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) Original (OR) Class B81B 3/0072 (20130101) B81B 2201/0235 (20130101) B81B 2201/0242 (20130101) B81B 2203/0109 (20130101) B81B 2203/0118 (20130101) B81B 2203/0127 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00531 (20130101) B81C 2201/019 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/1608 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649160 | Painter et al. |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annandale, Virginia) |
ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
FILED | Monday, November 02, 2020 |
APPL NO | 17/087316 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 3/0029 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 13/025 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649320 | Tropp et al. |
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FUNDED BY |
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APPLICANT(S) | Joshua Tropp (Hattiesburg, Mississippi); Douglas V. Amato (Hattiesburg, Mississippi); Derek L. Patton (Hattiesburg, Mississippi); Jason D. Azoulay (Hattiesburg, Mississippi) |
ASSIGNEE(S) | University of Southern Mississippi (Hattiesburg, Mississippi) |
INVENTOR(S) | Joshua Tropp (Hattiesburg, Mississippi); Douglas V. Amato (Hattiesburg, Mississippi); Derek L. Patton (Hattiesburg, Mississippi); Jason D. Azoulay (Hattiesburg, Mississippi) |
ABSTRACT | The present invention provides novel polymer compounds and methods and processes for polymerizing and synthesizing the new polymers by post-modifying conjugated polymers bearing unsaturated functionalities. The post-modifications are facilitated by light-mediated initiators, thermal initiators, redox-based initiators, small molecule-based initiators, or a combination thereof. Syntheses and post-modifications are carried out to high conversion via thiol-ene “click” chemistry-based mechanisms. The products comprise monomeric, oligomeric, and polymeric materials with easily-accessible pendant functionalities which impart new, distinct, and/or improved properties. |
FILED | Monday, September 23, 2019 |
APPL NO | 16/579694 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) C08G 61/126 (20130101) Original (OR) Class C08G 2261/18 (20130101) C08G 2261/78 (20130101) C08G 2261/124 (20130101) C08G 2261/145 (20130101) C08G 2261/228 (20130101) C08G 2261/1412 (20130101) C08G 2261/1426 (20130101) C08G 2261/3142 (20130101) C08G 2261/3223 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649446 | Isaacs et al. |
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FUNDED BY |
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APPLICANT(S) | Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
INVENTOR(S) | Farren Isaacs (Stamford, Connecticut); Miriam Amiram (Stamford, Connecticut); Adrian Haimovich (New Haven, Connecticut); Dieter Soil (Guilford, Connecticut) |
ABSTRACT | Compositions, systems, and methods for preparation of polypeptides having multiple iterations of non-standard amino acids are provided. The compositions and method can be used to produce recombinant proteins at a greater yield than the same or similar polypeptides made using conventional compositions, systems, and methods. Accordingly, in some embodiments, the polypeptides are ones that could not be made using conventional methods and reagents, or could not be made a sufficient yield or purity to serve a practical purpose using conventional methods and reagents. Polypeptides made using the disclosed compositions, systems, and methods are also provided. |
FILED | Wednesday, October 23, 2019 |
APPL NO | 16/661703 |
ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) Original (OR) Class C12N 15/102 (20130101) C12N 15/1058 (20130101) Enzymes C12Y 601/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649451 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Zhen Chen (Boston, Massachusetts); Phillip Andrew Lichtor (Cambridge, Massachusetts) |
ABSTRACT | The present invention provides methods and compositions for performing ordered multi-step syntheses involving modified nucleic acids by nucleic acid-mediated chemistry. This approach is useful for generating sequence-defined highly functionalized nucleic acid polymers. The invention also provides modified nucleic acid polymers that bind to proteins of interest (e.g., PCSK9 and IL-6), which are implicated in human disease. |
FILED | Friday, July 06, 2018 |
APPL NO | 16/629013 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7115 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1068 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650028 | Howell et al. |
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FUNDED BY |
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APPLICANT(S) | BRIGHAM YOUNG UNIVERSITY (Provo, Utah) |
ASSIGNEE(S) | BRIGHAM YOUNG UNIVERSITY (Provo, Utah) |
INVENTOR(S) | Larry L. Howell (Provo, Utah); Spencer P. Magleby (Provo, Utah); David C. Morgan (Provo, Utah); Terri Bateman (Provo, Utah); Jeffrey E. Niven (Provo, Utah); Alex Avila (Provo, Utah); Erica Crampton (Provo, Utah); Kyler Tolman (Provo, Utah); Jacob Greenwood (Provo, Utah); Peter Schleede (Provo, Utah) |
ABSTRACT | An example barrier can be switchable between an at least partially collapsed state and at least partially expanded state (e.g., a deployed state). For example, the barrier can be formed from a continuous sheet and a plurality of rigid sections (e.g., rigid panels) attached or incorporated into the continuous sheet. The barrier can also include a plurality of hinges, such as hinge lines, between the panels that are formed from the continuous sheet. The hinges enable the barrier to be rigid foldable (e.g., the hinges can fold and unfold while the rigid sections remain stiff and rigid) between the expanded and collapsed states. |
FILED | Wednesday, December 01, 2021 |
APPL NO | 17/539436 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Additional Work, Such as Equipping Roads or the Construction of Platforms, Helicopter Landing Stages, Signs, Snow Fences, or the Like E01F 13/02 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/06 (20130101) E06B 2009/007 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/04 (20130101) F41H 5/06 (20130101) Original (OR) Class F41H 5/013 (20130101) F41H 5/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650031 | Galloway et al. |
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FUNDED BY |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Kevin C. Galloway (Nashville, Tennessee); Kelsay E. Neely (Nashville, Tennessee); Aimee J. Valles (Nashville, Tennessee); Robert J. Clark (Nashville, Tennessee); Jesse L. Frederick (Nashville, Tennessee) |
ABSTRACT | Shaped charge devices, systems, and related methods of use. A housing sheet is configurable to form at least part of a shaped charge enclosure enclosing a shaped charge and biasing an explosion in a desired direction. The housing sheet can include one or more incisions in at least one surface thereof. The housing sheet can have at least one connection mechanism integrally formed therein, and the housing sheet can be configurable to form a plurality of sizes of shaped charge housing portions. The housing sheet can also provide for forming a plurality of dimensions of the shaped charge enclosure. |
FILED | Friday, August 07, 2020 |
APPL NO | 16/987933 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 1/028 (20130101) Original (OR) Class F42B 1/036 (20130101) F42B 3/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650034 | Hollis et al. |
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FUNDED BY |
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APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Michael Hollis (Flanders, New Jersey); Gary Dundon (Rockaway, New Jersey) |
ABSTRACT | Components of a projectile are held together by a captive collar that is internal to the projectile. The internal captive collar is rotated about a central boss, allowing external threads on the collar to engage one of the mating components and pull that mating component into the other mating component in an axial only translation. The internal captive collar is rotated using a geared-key during assembly. This key engages a geared crown feature of the captive collar, allowing it to rotate. After assembly, the gear key is removed from the assembly. Castellated features nest within slots to transmit torque in the assembled projectile. |
FILED | Thursday, March 24, 2022 |
APPL NO | 17/703605 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/20 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650040 | Provenzano |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
INVENTOR(S) | Daniel Provenzano (Philadelphia, Pennsylvania) |
ABSTRACT | A snubber gap measurement tool and a method for measuring snubber gaps in resilient mounts are provided. The tool has a handle, a stem, and a flag, and is sufficiently thin to fit within a resilient mount's inspection window. Upon rotation by 90 degrees the tool's flag extends within the snubber gap and thereby allows measurement of the snubber gap. |
FILED | Wednesday, June 30, 2021 |
APPL NO | 17/305107 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 5/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650042 | Saxer et al. |
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FUNDED BY |
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APPLICANT(S) | BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Christopher E. Saxer (Cary, North Carolina); Mark S. Branham (Oro Valley, Arizona); Jacob D. Garan (Honolulu, Hawaii) |
ABSTRACT | A laser transmission apparatus utilizing multiple laser beams and beam paths with a diverger lens to provide an illumination pattern that can compensate for lateral movement of the platform during shearography is provided. Further, this optical setup requires no moving parts and does not reduce power of the laser beams as they move through the individual components thereof. From the perspective of the surface being scanned or inspected, the present disclosure may provide two laser images of a single surface that appear to be identical despite the fact that they were taken from two different spatial positions of the moving platform. |
FILED | Friday, May 17, 2019 |
APPL NO | 16/414971 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02087 (20130101) G01B 9/02095 (20130101) G01B 9/02098 (20130101) Original (OR) Class G01B 11/162 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4815 (20130101) Optical Elements, Systems, or Apparatus G02B 27/48 (20130101) G02B 27/106 (20130101) G02B 27/123 (20130101) G02B 27/0955 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650130 | Gillaugh et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | Daniel Gillaugh (Troy, Ohio); Alexander Kaszynski (Layfayette, Colorado); Jeffrey Brown (Bellbrook, Ohio) |
ABSTRACT | The present disclosure is directed to a method and system to develop finite element (FE) models of as-manufactured turbomachinery blades using a combination of optical topography measurements, mesh morphing and strain gauge measurements. The method and system improves strain gauge to blade tip timing correlation using as-manufactured blade dimensions with finite element modeling. |
FILED | Tuesday, October 05, 2021 |
APPL NO | 17/493955 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/26 (20130101) G01B 11/0691 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/22 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650193 | Murdoch et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Heather A. Murdoch (Baltimore, Maryland); Christopher A. Schuh (Wayland, Massachusetts) |
ABSTRACT | Identifying a stable phase of a binary alloy comprising a solute element and a solvent element. In one example, at least two thermodynamic parameters associated with grain growth and phase separation of the binary alloy are determined, and the stable phase of the binary alloy is identified based on the first thermodynamic parameter and the second thermodynamic parameter, wherein the stable phase is one of a stable nanocrystalline phase, a metastable nanocrystalline phase, and a non-nanocrystalline phase. In different aspects, an enthalpy of mixing of the binary alloy may be calculated as a first thermodynamic parameter, and an enthalpy of segregation of the binary alloy may be calculated as a second thermodynamic parameter. In another example, a diagram delineating a plurality of regions respectively representing different stable phases of at least one binary alloy is employed, wherein respective regions of the plurality of regions are delineated by at least one boundary determined as a function of at least two thermodynamic parameters associated with grain growth and phase separation of the at least one binary alloy. |
FILED | Tuesday, January 22, 2019 |
APPL NO | 16/254570 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Alloys C22C 1/00 (20130101) C22C 5/02 (20130101) C22C 5/04 (20130101) C22C 5/06 (20130101) C22C 7/00 (20130101) C22C 11/00 (20130101) C22C 12/00 (20130101) C22C 13/00 (20130101) C22C 16/00 (20130101) C22C 20/00 (20130101) C22C 22/00 (20130101) C22C 24/00 (20130101) C22C 27/00 (20130101) C22C 27/02 (20130101) C22C 27/04 (20130101) C22C 27/06 (20130101) C22C 27/025 (20130101) C22C 28/00 (20130101) C22C 38/002 (20130101) C22C 43/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/02 (20130101) G01N 25/12 (20130101) G01N 33/204 (20190101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650222 | Moheimani et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Seyed Omid Reza Moheimani (Allen, Texas); Hamed Alemansour (Richardson, Texas) |
ABSTRACT | In the system and method disclosed, an ultrahigh vacuum (UHV) scanning tunneling microscope (STM) tip is used to selectively desorb hydrogen atoms from the Si(100)-2X1:H surface by injecting electrons at a negative sample bias voltage. A new lithography method is disclosed that allows the STM to operate under imaging conditions and simultaneously desorb H atoms as required. A high frequency signal is added to the negative sample bias voltage to deliver the required energy for hydrogen removal. The resulted current at this frequency and its harmonics are filtered to minimize their effect on the operation of the STM's feedback loop. This approach offers a significant potential for controlled and precise removal of hydrogen atoms from a hydrogen-terminated silicon surface and thus may be used for the fabrication of practical silicon-based atomic-scale devices. |
FILED | Thursday, September 30, 2021 |
APPL NO | 17/490925 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 10/065 (20130101) Original (OR) Class G01Q 60/10 (20130101) G01Q 80/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/26 (20130101) H01J 37/28 (20130101) H01J 37/3174 (20130101) H01J 2237/2818 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650339 | Nelson |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Kyle Alan Nelson (San Diego, California) |
ABSTRACT | A sensor for spectroscopic measurement of alpha and beta particles includes first and second layers, a photomultiplier, and an analyzer. A first material of the first layer scintillates a first stream of photons for each of the alpha particles. However, the beta particles pass through the first layer. A second material of the second layer scintillates a second stream of photons for each of the beta particles, but passes the first stream of photons for each alpha particle. The photomultiplier amplifies the first and second streams of photons for the alpha and beta particles into an electrical signal. The electrical signal includes a respective pulse for each of the alpha and beta particles. From the electrical signal, the analyzer determines a respective energy of each of the alpha and/or beta particles from a shape of the respective pulse for each of the alpha and beta particles. |
FILED | Tuesday, May 12, 2020 |
APPL NO | 15/930117 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/362 (20130101) Original (OR) Class G01T 1/20181 (20200501) G01T 1/20184 (20200501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650370 | Chandrahalim et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | Hengky Chandrahalim (Beavercreek, Ohio); Kyle T Bodily (Xenia, Ohio) |
ABSTRACT | The present invention relates to evanescently coupling whispering gallery mode optical resonators having a liquid coupling as well as methods of making and using same. The aforementioned evanescently coupling whispering gallery mode optical resonators having a liquid couplings provide increased tunability and sensing selectivity over current same. The aforementioned. Applicants' method of making evanescent-wave coupled optical resonators can be achieved while having coupling gap dimensions that can be fabricated using standard photolithography. Thus economic, rapid, and mass production of coupled WGM resonators-based lasers, sensors, and signal processors for a broad range of applications can be realized. |
FILED | Thursday, October 21, 2021 |
APPL NO | 17/506854 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/29341 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650440 | De Cea Falco et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Marc De Cea Falco (Cambridge, Massachusetts); Amir H. Atabaki (San Francisco, California); Rajeev J. Ram (Arlington, Massachusetts) |
ABSTRACT | A photovoltaic modulator utilizes free carriers generated by absorption of optical radiation passing through the modulator to achieve ultra-low energy modulation of the radiation. The photovoltaic modulator can also function as an electro-optic transducer for low-power, low-EMI, high-density sensing applications. |
FILED | Monday, June 21, 2021 |
APPL NO | 17/353081 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) Original (OR) Class G02F 1/2257 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0745 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650578 | Behandish et al. |
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FUNDED BY |
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APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
INVENTOR(S) | Morad Behandish (Mountain View, California); Saigopal Nelaturi (Mountain View, California) |
ABSTRACT | Two or more computational services are defined that each represent a respective different manufacturing capability used to partially create a target part model. A common space shared among the computational services is defined to reference the target part model and manufacturing primitives corresponding to each capability. The computational services are queried to construct a logical representation of the planning space based on intersections among the primitives. One or more process plans are formed using the different manufacturing capabilities to manufacture the part. |
FILED | Monday, August 09, 2021 |
APPL NO | 17/397499 |
ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4183 (20130101) G05B 19/4188 (20130101) Original (OR) Class G05B 19/41885 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650652 | Ardanaz et al. |
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FUNDED BY |
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APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
ASSIGNEE(S) | INTEL CORPORATION (Santa Clara, California) |
INVENTOR(S) | Federico Ardanaz (Hillsboro, Oregon); Jonathan M. Eastep (Portland, Oregon); Richard J. Greco (West Linn, Oregon); Ramkumar Nagappan (Chandler, Arizona); Alan B. Kyker (Winters, California) |
ABSTRACT | Apparatus, systems, and methods provide an interface between a plurality of hardware resources of a node and a power manager. The interface is configured to define one or more resource groups to expose to the power manager for power measurement and control, assign the plurality of hardware resources to the one or more resource groups, and provide a power allowance to each resource group. |
FILED | Thursday, June 24, 2021 |
APPL NO | 17/357479 |
ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 1/325 (20130101) Original (OR) Class G06F 1/3287 (20130101) G06F 1/3293 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651194 | Ren et al. |
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FUNDED BY |
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APPLICANT(S) | NVIDIA Corp. (Santa Clara, California) |
ASSIGNEE(S) | NVIDIA Corp. (Santa Clara, California) |
INVENTOR(S) | Haoxing Ren (Austin, Texas); George Kokai (Cupertino, California); Ting Ku (San Jose, California); Walker Joseph Turner (Raleigh, North Carolina) |
ABSTRACT | A graph neural network to predict net parasitics and device parameters by transforming circuit schematics into heterogeneous graphs and performing predictions on the graphs. The system may achieve an improved prediction rate and reduce simulation errors. |
FILED | Monday, April 27, 2020 |
APPL NO | 16/859585 |
ART UNIT | 2436 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 16/9024 (20190101) G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651231 | Hoskins et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
INVENTOR(S) | Brian Douglas Hoskins (North Bethesda, Maryland); Mark David Stiles (Silver Spring, Maryland); Matthew William Daniels (Bethesda, Maryland); Advait Madhavan (Silver Spring, Maryland); Gina Cristina Adam (Washington, District of Columbia) |
ABSTRACT | A quasi-systolic array includes: a primary quasi-systolic processor; an edge row bank and edge column bank of edge quasi-systolic processors; and an interior bank of interior quasi-systolic processors. The primary quasi-systolic processor, edge quasi-systolic processor, and interior quasi-systolic processor independently include a quasi-systolic processor and are disposed and electrically connected in rows and columns in the quasi-systolic array. |
FILED | Monday, March 02, 2020 |
APPL NO | 16/806121 |
ART UNIT | 2182 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) G06F 2207/4824 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/10 (20130101) Original (OR) Class G06N 3/0635 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651261 | Harris |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
INVENTOR(S) | Daniel E. Harris (Huntsville, Alabama) |
ABSTRACT | A computer-implemented method includes receiving a plurality of expert datasets representing computer-generated beliefs; generating respective expert tensors for each expert dataset; fusing each of the respective expert tensors into a final result tensor, wherein the final result tensor represents the simultaneous fusing of the plurality of expert datasets; and storing or outputting the final result for use in an application. |
FILED | Tuesday, October 29, 2019 |
APPL NO | 16/667722 |
ART UNIT | 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/027 (20130101) G06N 7/01 (20230101) Original (OR) Class G06N 20/00 (20190101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651267 | Monroe et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (, None) |
INVENTOR(S) | Christopher Monroe (Ellicott City, Maryland); Martin Lichtman (Philadelphia, Pennsylvania); Ismail Volkan Inlek (Cary, North Carolina); Clayton Crocker (Hyattsville, Maryland); Ksenia Sosnova (Silver Spring, Maryland) |
ABSTRACT | The disclosure describes aspects of using multiple species in trapped-ion nodes for quantum networking. In an aspect, a quantum networking node is described that includes multiple memory qubits, each memory qubit being based on a 171Yb+ atomic ion, and one or more communication qubits, each communication qubit being based on a 138Ba+ atomic ion. The memory and communication qubits are part of a lattice in an atomic ion trap. In another aspect, a quantum computing system having a modular optical architecture is described that includes multiple quantum networking nodes, each quantum networking node including multiple memory qubits (e.g., based on a 171Yb+ atomic ion) and one or more communication qubits (e.g., based on a 138Ba+ atomic ion). The memory and communication qubits are part of a lattice in an atomic ion trap. The system further includes a photonic entangler coupled to each of the multiple quantum networking nodes. |
FILED | Tuesday, March 29, 2022 |
APPL NO | 17/707541 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Electric Digital Data Processing G06F 9/3877 (20130101) G06F 9/5027 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/422 (20130101) Transmission H04B 10/70 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0858 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651270 | Castelli et al. |
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FUNDED BY |
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APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Vittorio Castelli (Croton on Hudson, New York); Radu Florian (Danbury, Connecticut); Taesun Moon (Scarsdale, New York); Avirup Sil (Ossining, New York) |
ABSTRACT | A method and system are provided for combining models. The method includes forming, by a computer having a processor and a memory, model pairs from a model ensemble that includes a plurality of models. The method further includes comparing the model pairs based on sets of output results produced by the model pairs to provide comparison results. The method also includes constructing, by the computer, a combination model from at least one of the model pairs based on the comparison results. The comparing step is performed using user-generated set-based feedback. |
FILED | Tuesday, March 22, 2016 |
APPL NO | 15/077303 |
ART UNIT | 2126 — AI & Simulation/Modeling |
CURRENT CPC | Electric Digital Data Processing G06F 16/3326 (20190101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class G06N 20/20 (20190101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651850 | Ward et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Kevin Ward (Glen Allen, Virginia); Daniel Francis Taylor (Belleville, Michigan); Michael W. Sjoding (Ann Arbor, Michigan); Christopher Elliot Gillies (Ann Arbor, Michigan) |
ABSTRACT | A computer-implemented method includes preprocessing a variable dimension medical image, identifying one or more areas of interest in the medical image; and analyzing the one or more areas of interest using a deep learning model. A computing system includes one or more processors; and one or more memories storing instructions that, when executed by the one or more processors, cause the computing system to preprocess a variable dimension medical image, identify one or more areas of interest in the medical image; and analyze the one or more areas of interest using a deep learning model. A non-transitory computer readable medium contains program instructions that when executed, cause a computer to preprocess a variable dimension medical image, identify one or more areas of interest in the medical image, and analyze the one or more areas of interest using a deep learning model. |
FILED | Wednesday, October 28, 2020 |
APPL NO | 17/082145 |
ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 11/20 (20130101) G06T 2207/10116 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30061 (20130101) G06T 2210/12 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652129 | Vincentsen et al. |
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FUNDED BY |
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APPLICANT(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
ASSIGNEE(S) | Wavefront Research, Inc. (Northhampton, Pennsylvania) |
INVENTOR(S) | David M. Vincentsen (Bethlehem, Pennsylvania); Jonas D. Corl (Bethlehem, Pennsylvania); Thomas A. Mitchell (Northampton, Pennsylvania); Michelle M. Stone (Hellertown, Pennsylvania); Thomas W. Stone (Hellertown, Pennsylvania); Randall C. Veitch (Walnutport, Pennsylvania) |
ABSTRACT | The present disclosure provides an optoelectronic module. In one aspect, the optoelectronic module includes an insertion member including a housing insert and an imager disposed in the housing insert, and a receiving member including an interposer, a housing disposed on the interposer, and an optoelectronic device electrically connected to said interposer. The housing of the receiving member is configured to engage and receive the housing insert of the insertion member. The optoelectronic device of the receiving member is configured to align with the imager of the insertion member. |
FILED | Monday, June 21, 2021 |
APPL NO | 17/353695 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14618 (20130101) H01L 27/14636 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652183 | Zheng et al. |
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FUNDED BY |
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APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
INVENTOR(S) | Bob Yi Zheng (Houston, Texas); Hangqi Zhao (Houston, Texas); Benjamin Cerjan (Houston, Texas); Mehbuba Tanzid (Houston, Texas); Peter J. Nordlander (Houston, Texas); Nancy J. Halas (Houston, Texas) |
ABSTRACT | An infrared photodetector includes: a p-type and highly-doped silicon substrate; a metal structure disposed on the silicon substrate; a first electric contact to the silicon substrate; and a second electric contact to the metal structure. |
FILED | Friday, June 12, 2020 |
APPL NO | 16/899759 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/20 (20130101) G01J 2005/0077 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/101 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652395 | Miesner |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | John E. Miesner (Fairfax, Virginia) |
ABSTRACT | Inertial actuators are provided, which use a one-dimensional or a two-dimensional voice coil array to achieve the same force output performance as a monolithic actuator. The voice coil arrays use less permanent magnet and flux conducting material, and have a lower inductance, while achieving increased frequency bandwidth. |
FILED | Friday, March 04, 2022 |
APPL NO | 17/686535 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Dynamo-electric Machines H02K 33/18 (20130101) H02K 41/0354 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652473 | Curbow et al. |
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FUNDED BY |
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APPLICANT(S) | Cree Fayetteville, Inc. (Fayetteville, Arkansas) |
ASSIGNEE(S) | WOLFSPEED, INC. (Durham, North Carolina) |
INVENTOR(S) | Austin Curbow (Fayetteville, Arkansas); Daniel Martin (Fayetteville, Arkansas) |
ABSTRACT | The disclosure is directed to a power module apparatus that includes a base plate, a power substrate positioned relative to the base plate, at least two power contacts, a gate-source board mounted relative to the power substrate, gate drive connectors electrically connected to the gate-source board, a housing secured to the power substrate, and a clamping circuit electrically connected to the at least one power device. The clamping circuit being configured to clamp an input to a gate of the at least one power device. The clamping circuit being arranged with at least one of the following: the base plate, the power substrate, one of the at least two power contacts, the at least one power device, the gate-source board, the gate drive connectors, and the housing. The disclosure is further directed to a process of configuring a power module apparatus. |
FILED | Friday, December 16, 2016 |
APPL NO | 15/382172 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/00 (20130101) H01L 25/072 (20130101) H01L 2224/48091 (20130101) H01L 2224/48091 (20130101) H01L 2924/00014 (20130101) Pulse Technique H03K 3/013 (20130101) Original (OR) Class H03K 5/08 (20130101) H03K 17/165 (20130101) H03K 17/0822 (20130101) H03K 17/0826 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) H05K 1/0306 (20130101) H05K 2201/10166 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652478 | Curbow et al. |
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FUNDED BY |
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APPLICANT(S) | Cree Fayetteville, Inc. (Fayetteville, Arkansas) |
ASSIGNEE(S) | WOLFSPEED, INC. (Durham, North Carolina) |
INVENTOR(S) | Austin Curbow (Fayetteville, Arkansas); Daniel Martin (Fayetteville, Arkansas) |
ABSTRACT | A power module apparatus includes a power substrate, at least one power device electrically connected to the power substrate and a gate-source board mounted relative to the power substrate, the gate-source board electrically connected to the at least one power device, a housing secured to the power substrate, and a clamping circuit electrically connected to the at least one power device. The clamping circuit being configured to reduce a voltage charge up at a gate of the at least one power device to within 8 V of a desired voltage. |
FILED | Friday, February 24, 2017 |
APPL NO | 15/441857 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Pulse Technique H03K 5/08 (20130101) H03K 17/063 (20130101) H03K 17/163 (20130101) H03K 17/165 (20130101) Original (OR) Class H03K 17/168 (20130101) H03K 2017/066 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/145 (20130101) H05K 1/181 (20130101) H05K 1/182 (20130101) H05K 7/1432 (20130101) H05K 2201/042 (20130101) H05K 2201/10166 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652557 | Zheng et al. |
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FUNDED BY |
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APPLICANT(S) | Yahong Rosa Zheng (Rolla, Missouri); Weimin Duan (San Diego, California); Chengshan Xiao (Rolla, Missouri) |
ASSIGNEE(S) | UNIVERSITY OF MISSOURI (Columbia, Missouri) |
INVENTOR(S) | Yahong Rosa Zheng (Rolla, Missouri); Weimin Duan (San Diego, California); Chengshan Xiao (Rolla, Missouri) |
ABSTRACT | Aspects of the present disclosure include methods for communication using a MIMO channel, such as an acoustic channel for underwater communication. An acoustic receiver may receive a signal comprising information encoded in at least one transmitted symbol. Using a two-layer iterative process, the at least one transmitted symbol is estimated. The first layer of the two-layer process uses iterative exchanges of soft-decisions between an adaptive turbo equalizer and a MAP decoder. The second layer of the two-layer process uses a data-reuse procedure that adapts an equalizer vector of both a feedforward filter and a serial interference cancellation filter of the adaptive turbo equalizer using a posteriori soft decisions of the at least one transmitted symbol. After a plurality of iterations, a hard decision of the bits encoded on the at least one transmitted symbol is output from the MAP decoder. |
FILED | Tuesday, March 17, 2020 |
APPL NO | 16/821816 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Transmission H04B 11/00 (20130101) H04B 13/02 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/03057 (20130101) H04L 27/0008 (20130101) H04L 2025/03426 (20130101) H04L 2025/03636 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652839 | Aloisio et al. |
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FUNDED BY |
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APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
INVENTOR(S) | Scott Aloisio (Willseyville, New York); Robert A. Joyce (Ithaca, New York); Kenneth McVearry (Dewitt, New York); Mark E. Peters (Newport News, Virginia) |
ABSTRACT | An attack tree model for an aviation system comprises a plurality of tree nodes organized as a tree. For each tree node of the attack tree model model, the tree node corresponds to a respective event that may befall aviation system. An analysis computing system generates one or more attack tree models for the aviation system, wherein the aviation system includes one or more systems, sub-systems, or components. The analysis computing system further performs an assessment of one or more of the system, sub-systems, or components of the aviation system using the one or more attack tree models, and outputs metrics indicative of the assessment. |
FILED | Thursday, May 02, 2019 |
APPL NO | 16/401592 |
ART UNIT | 2492 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/577 (20130101) G06F 2221/034 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1408 (20130101) H04L 63/1416 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 63/1441 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11653125 | Kobold |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Michael Kobold (Panama City, Florida) |
ABSTRACT | A data collection method uses a receiver having data collection sensitivity to signals originating from objects dispersed in a field that is subject to distortion. The sensitivity of the receiver is swept along a first arc. For each of the objects detected during the sweeping step, two of the signals are collected at two different points in time. A difference between the two signals is compared to a threshold. When the difference exceeds the threshold, the sensitivity of the receiver is re-swept along a second arc that is angularly less than the first arc. When the difference is less than the threshold, the signals are captured. |
FILED | Friday, April 16, 2021 |
APPL NO | 17/233125 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Selecting H04Q 9/00 (20130101) Original (OR) Class H04Q 2209/10 (20130101) H04Q 2209/40 (20130101) H04Q 2209/756 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 11648241 | Abergel et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Rebecca J. Abergel (Kensington, California); Taylor A. Choi (South San Francisco, California); Kenneth N. Raymond (Berkeley, California); David K. Shuh (Oakland, California) |
ABSTRACT | Provided herein are pharmaceutical formularions comprising a 1,2-HOPO chelating agent and/or 3,2-HOPO chelating agent. |
FILED | Tuesday, September 05, 2017 |
APPL NO | 16/330601 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0056 (20130101) A61K 9/0095 (20130101) A61K 9/1611 (20130101) A61K 9/1623 (20130101) A61K 9/1652 (20130101) A61K 9/2009 (20130101) A61K 9/2018 (20130101) A61K 9/2054 (20130101) A61K 31/444 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/04 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648546 | Elam et al. |
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FUNDED BY |
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APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Jeffrey W. Elam (Elmhurst, Illinois); Christian P. Canlas (Westmont, Illinois) |
ABSTRACT | Zeolites are industrially important materials possessing high Bronsted acidity and shape-selectivity. However, their inherently small pores restrict application for catalytic conversion of bulky molecules. A method of synthesis of ‘artificial’ zeolites. The artificial zeolites have well-tailored Bronsted and Lewis acid sites prepared on mesostructured silica to circumvent this limitation. This novel approach utilizes atomic layer deposition to tailor both porosity and acid speciation, providing exquisite control over catalytic behavior and enabling systematic studies. |
FILED | Thursday, January 29, 2015 |
APPL NO | 14/609276 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/12 (20130101) B01J 29/06 (20130101) B01J 31/22 (20130101) Original (OR) Class B01J 35/02 (20130101) B01J 35/0006 (20130101) B01J 35/1023 (20130101) B01J 35/1061 (20130101) B01J 37/0246 (20130101) B01J 37/348 (20130101) B01J 2229/12 (20130101) B01J 2229/32 (20130101) B01J 2229/60 (20130101) B01J 2229/186 (20130101) B01J 2231/76 (20130101) B01J 2531/002 (20130101) B01J 2531/008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648706 | Lee et al. |
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FUNDED BY |
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APPLICANT(S) | San Diego State University (San Diego, California) |
ASSIGNEE(S) | San Diego State University Research Foundation (San Diego, California) |
INVENTOR(S) | Geuntak Lee (Seoul, South Korea); Eugene Olevsky (San Diego, California); Charles Maniere (Toulouse, France) |
ABSTRACT | The invention relates to a process for fabricating complex mechanical shapes from metal or ceramic, and in particular to fabricating complex mechanical shapes using a pressure-assisted sintering technique to address problems relating to variations in specimen thickness and tooling, or densification gradients, by 3-D printing of a sacrificial, self-destructing powder mold is created using e.g. alumina and swellable binders such as polysaccharides. The binder-free sintering powder that forms the manufactured item is injected into the mold, and high pressure is applied. The powder assembly can then be sintered by any pressure assisted technique to full densification and the self-destructing mold allows the release of the fully densified complex manufactured item. |
FILED | Friday, April 26, 2019 |
APPL NO | 17/050835 |
ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 5/77 (20170201) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/04 (20130101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) B28B 7/342 (20130101) Original (OR) Class B28B 7/346 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) B33Y 80/00 (20141201) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/10 (20130101) C04B 35/48 (20130101) C04B 35/6455 (20130101) C04B 2235/3217 (20130101) C04B 2235/3244 (20130101) C04B 2235/3246 (20130101) C04B 2235/6026 (20130101) C04B 2235/6562 (20130101) C04B 2235/6567 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649198 | Weaver et al. |
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FUNDED BY |
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APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
INVENTOR(S) | Jason F. Weaver (Gainesville, Florida); Yingxue Bian (Golden, Colorado) |
ABSTRACT | Methods of converting ethane to ethylene at relatively low temperatures are described. IrO2-based catalysts are used in the conversion. Methods of converting a base gas to a first gas by exposing the base gas to an IrO2-based catalyst and forming the first gas are described. The base gas can be an alkane. The first gas can include an alkene, an alkyne, an alcohol, an aldehyde, or combinations thereof. |
FILED | Wednesday, November 17, 2021 |
APPL NO | 17/528675 |
ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/468 (20130101) Acyclic or Carbocyclic Compounds C07C 5/3337 (20130101) Original (OR) Class C07C 11/04 (20130101) C07C 2523/46 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649358 | Liao et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Chen Liao (Westmont, Illinois); Trevor L. Dzwiniel (Carol Stream, Illinois); Kewel Liu (Aurora, Illinois) |
ABSTRACT | Described herein are borate salts useful as additives, binders, and electrolyte salts for solid state lithium ion batteries. In particular, the borate salts of Formula (I), Formula (II) and Formula (III) as described herein: can be polymerized, or can be bound to an existing polymer, to provide polymeric binders for ceramic solid state electrolytes that are themselves capable of ion transport independent of the ceramic. |
FILED | Wednesday, September 11, 2019 |
APPL NO | 16/567647 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/37 (20130101) Compositions of Macromolecular Compounds C08L 85/04 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/622 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 2300/0091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649410 | Hafenstine et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
INVENTOR(S) | Glenn Richard Hafenstine (Wheat Ridge, Colorado); Derek Richard Vardon (Lakewood, Colorado); Xiangchen Huo (Golden, Colorado); Nabila Asem Huq (Boulder, Colorado) |
ABSTRACT | The present disclosure relates to a composition that includes a first oxide having a phosphate, a ratio of Brønsted acid sites to Lewis acid sites between 0.05 and 1.00, and a total acidity between 50 μmol/g and 300 μmol/g, where the phosphate is at least one of a functional group covalently bonded to the first oxide and/or an anion ionically bonded to the first oxide. |
FILED | Monday, July 19, 2021 |
APPL NO | 17/379477 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/44 (20130101) B01J 27/195 (20130101) B01J 27/1802 (20130101) B01J 35/023 (20130101) B01J 35/026 (20130101) B01J 35/1014 (20130101) B01J 35/1019 (20130101) B01J 35/1038 (20130101) B01J 35/1042 (20130101) Acyclic or Carbocyclic Compounds C07C 41/09 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) C10L 1/023 (20130101) C10L 1/026 (20130101) Original (OR) Class C10L 2200/0423 (20130101) C10L 2200/0446 (20130101) C10L 2270/023 (20130101) C10L 2270/026 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649450 | Kunjapur et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Aditya Mohan Kunjapur (Cambridge, Massachusetts); George M. Church (Brookline, Massachusetts) |
ABSTRACT | The disclosure provides methods of making a protein having a desired non-standard amino acid incorporated at its N-terminus in a cell and methods of screening for an amino acyl tRNA synthetase variant that preferentially selects a non-standard amino acid against its standard amino acid counterpart or undesired non-standard amino acids for incorporation into a protein in a cell. |
FILED | Friday, June 29, 2018 |
APPL NO | 16/627077 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) C12N 9/93 (20130101) C12N 15/74 (20130101) C12N 15/90 (20130101) C12N 15/1058 (20130101) Original (OR) Class Enzymes C12Y 601/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649469 | Church et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | George M. Church (Brookline, Massachusetts); Kevin M. Esvelt (Auburndale, Massachusetts); Prashant G. Mali (La Jolla, California) |
ABSTRACT | Methods of modulating expression of a target nucleic acid in a cell are provided including use of multiple orthogonal Cas9 proteins to simultaneously and independently regulate corresponding genes or simultaneously and independently edit corresponding genes. |
FILED | Tuesday, May 14, 2019 |
APPL NO | 16/411793 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 2/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/85 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/3519 (20130101) C12N 2320/33 (20130101) C12N 2320/50 (20130101) C12N 2800/40 (20130101) C12N 2800/80 (20130101) C12N 2800/107 (20130101) C12N 2810/10 (20130101) C12N 2830/00 (20130101) C12N 2830/34 (20130101) C12N 2999/007 (20130101) Enzymes C12Y 301/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649472 | Park et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Junyoung Park (Cambridge, Massachusetts); Nian Liu (Cambridge, Massachusetts); Gregory Stephanopoulos (Winchester, Massachusetts) |
ABSTRACT | The disclosure provides methods using mixed substrate cofeeding for bioproduct synthesis, which enables faster, more efficient, and higher yield carbon conversion in various organisms. |
FILED | Friday, June 29, 2018 |
APPL NO | 16/023336 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/16 (20130101) C12N 1/32 (20130101) C12N 1/205 (20210501) C12N 9/22 (20130101) C12N 9/2437 (20130101) C12N 9/2474 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/54 (20130101) Original (OR) Class C12P 7/64 (20130101) C12P 7/6409 (20130101) C12P 7/6463 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/02 (20210501) C12R 2001/145 (20210501) Enzymes C12Y 302/01004 (20130101) C12Y 302/01035 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649537 | Palasyuk et al. |
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FUNDED BY |
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APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | Andriy Palasyuk (Ames, Iowa); Tej Nath Lamichhane (Ames, Iowa); Olena Palasyuk (Ames, Iowa); Vladimir Antropov (Ames, Iowa); Paul C. Canfield (Ames, Iowa); Ralph W. McCallum (Santa Fe, New Mexico) |
ABSTRACT | Provided are Ce/Co/Cu permanent magnet alloys containing certain refractory metals, such as Ta and/or Hf, and optionally Fe which represent economically more favorable alternative to Sm-based magnets with respect to both material and processing costs and which retain and/or improve magnetic characteristics useful for GAP MAGNET applications. |
FILED | Monday, December 10, 2018 |
APPL NO | 16/350612 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Alloys C22C 19/07 (20130101) C22C 2202/02 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/10 (20130101) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/52 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/047 (20130101) H01F 1/055 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649707 | Sheng |
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FUNDED BY |
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APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
INVENTOR(S) | James J. Sheng (Lubbock, Texas) |
ABSTRACT | Methods for optimization of liquid oil production by huff-n-puff in shale reservoirs to achieve an improved (and optimal) oil recovery factor. The process determines and utilizes the optimum huff and puff times, number of cycles and soaking time under practical operation and reservoir conditions. The huff time in the process is a period so long that the pressure near the wellbore reaches the set maximum injection pressure during the huff period. The puff time in the process is the time required for the pressure near the wellbore to reach the set minimum production pressure during the puff period. Soaking is typically not necessary during the huff-n-puff gas injection in shale oil reservoirs. The number of huff-n-puff cycles is determinable by the time in which the economic rate cut-off is reached. |
FILED | Friday, April 02, 2021 |
APPL NO | 17/221073 |
ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/168 (20130101) Original (OR) Class E21B 47/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649777 | Carpenter, III et al. |
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FUNDED BY |
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APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, New Caledonia) |
INVENTOR(S) | John Reeves Carpenter, III (Research Triangle Park, North Carolina); David Douglas Barbee (Research Triangle Park, North Carolina); Apoorv Agarwal (Research Triangle Park, North Carolina) |
ABSTRACT | An internal combustion engine is operated at fuel-rich conditions by adjusting one or more operating parameters such as, for example, a throttle, an ignition timing, a load coupled to the engine, a fuel pressure, power to a supercharger, and power to a preheater to maintain a specified engine speed and a temperature of an exhaust gas. Operating the engine under these conditions allows the engine to function as a reformer producing a synthesis gas comprising hydrogen and carbon monoxide. |
FILED | Monday, September 24, 2018 |
APPL NO | 16/652307 |
ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 37/12 (20130101) Controlling Combustion Engines F02D 41/0002 (20130101) F02D 41/062 (20130101) Original (OR) Class F02D 41/1446 (20130101) F02D 41/1454 (20130101) F02D 2200/10 (20130101) F02D 2200/023 (20130101) F02D 2200/0602 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 31/16 (20130101) Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines F02P 5/142 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649992 | Holladay et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington); Emerald Energy NW, LLC (Bothell, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington); Emerald Energy NW, LLC (Bothell, Washington) |
INVENTOR(S) | Jamie D. Holladay (Richland, Washington); Kerry D. Meinhardt (Kennewick, Washington); Evgueni Polikarpov (Richland, Washington); Edwin C. Thomsen (Richland, Washington); John Barclay (Richland, Washington) |
ABSTRACT | A process for liquefying a process gas that includes introducing a heat transfer fluid into an active magnetic regenerative refrigerator apparatus that comprises a single stage comprising dual multilayer regenerators located axially opposite to each other. |
FILED | Tuesday, November 02, 2021 |
APPL NO | 17/517150 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) Original (OR) Class F25B 2321/0021 (20130101) F25B 2321/0022 (20130101) Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 11/02 (20130101) Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 1/001 (20130101) F25J 2270/908 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/0275 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/012 (20130101) Electric solid-state devices not otherwise provided for H10N 15/20 (20230201) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 30/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650016 | Swartz et al. |
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FUNDED BY |
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APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
INVENTOR(S) | Matthew M. Swartz (Claridge, Pennsylvania); William A. Byers (Murrysville, Pennsylvania); John Lojek, III (Valencia, Pennsylvania) |
ABSTRACT | A heat pipe is disclosed includes a container, a container lid including a groove defined therein, a wick, and an end plug operably coupled to the wick. The end plug includes a pin extending therefrom. The groove of the container lid is configured to receive the pin. |
FILED | Monday, April 20, 2020 |
APPL NO | 16/853345 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/046 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650222 | Moheimani et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | Seyed Omid Reza Moheimani (Allen, Texas); Hamed Alemansour (Richardson, Texas) |
ABSTRACT | In the system and method disclosed, an ultrahigh vacuum (UHV) scanning tunneling microscope (STM) tip is used to selectively desorb hydrogen atoms from the Si(100)-2X1:H surface by injecting electrons at a negative sample bias voltage. A new lithography method is disclosed that allows the STM to operate under imaging conditions and simultaneously desorb H atoms as required. A high frequency signal is added to the negative sample bias voltage to deliver the required energy for hydrogen removal. The resulted current at this frequency and its harmonics are filtered to minimize their effect on the operation of the STM's feedback loop. This approach offers a significant potential for controlled and precise removal of hydrogen atoms from a hydrogen-terminated silicon surface and thus may be used for the fabrication of practical silicon-based atomic-scale devices. |
FILED | Thursday, September 30, 2021 |
APPL NO | 17/490925 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 10/065 (20130101) Original (OR) Class G01Q 60/10 (20130101) G01Q 80/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/26 (20130101) H01J 37/28 (20130101) H01J 37/3174 (20130101) H01J 2237/2818 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651082 | Gourisetti et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington); The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington); The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
INVENTOR(S) | Sri Nikhil Gupta Gourisetti (Richland, Washington); Michael E. Mylrea (Alexandria, Virginia); Hirak Patangia (Little Rock, Arkansas) |
ABSTRACT | Technology related to blockchain cybersecurity solutions and a blockchain applicability framework is disclosed. In one example of the disclosed technology, a system is configured to receive parameters for a blockchain candidate application and evaluate the parameters to determine a recommendation for types of blockchain to apply to the candidate application. The recommendation may be based on an evaluation of the parameters to determine a level of applicability of blockchain usage, a level of applicability of one or more blockchain privacy types, and a level of applicability of one or more blockchain consensus types. The system may be configured to calculate an overall percentage distribution of the levels of applicability and to output an indication of the overall percentage distribution. |
FILED | Friday, July 10, 2020 |
APPL NO | 16/926600 |
ART UNIT | 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
CURRENT CPC | Electric Digital Data Processing G06F 16/27 (20190101) G06F 21/577 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06375 (20130101) G06Q 30/018 (20130101) G06Q 50/06 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/50 (20220501) H04L 9/0637 (20130101) H04L 9/3236 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651839 | Sankaranarayanan et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
INVENTOR(S) | Subramanian Sankaranarayanan (Naperville, Illinois); Troy David Loeffler (Chicago, Illinois); Henry Chan (Schaumburg, Illinois); Mathew J. Cherukara (Darien, Illinois); Srilok Srinivasan (Woodridge, Illinois) |
ABSTRACT | A system can include one or more processors configured to access at least one parameter of a material, generate a plurality of structures of the material using the at least one parameter, determine a state of each structure of the plurality of structures using the at least one parameter, determine a difference between the state of each structure of the plurality of structures and a ground state value, evaluate a convergence condition responsive to determining the difference between the state of each structure of the plurality of structures and the ground state value, and output at least one structure of the plurality of structures responsive to the convergence condition being satisfied. |
FILED | Monday, March 02, 2020 |
APPL NO | 16/807081 |
ART UNIT | 2897 — Semiconductors/Memory |
CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/00 (20190201) G16C 20/30 (20190201) Original (OR) Class G16C 20/70 (20190201) G16C 20/80 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651874 | Podpaly et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Yuri Anatoly Podpaly (Hayward, California); Michael Gordon Anderson (Discovery Bay, California); Steve Hawkins (Livermore, California); Alexander Peter Povilus (Livermore, California); Chris Vice (Livermore, California) |
ABSTRACT | High-voltage insulators are disclosed that are capable of handling diverse requirements, such as providing high standoff voltages, high temperature cycling, and the ability to withstand flexural stress. One high-voltage insulator includes a first piece formed from a first material, a second piece formed from a second material, and an interface section where the first piece contacts with and forms a seal with the second piece. The interface includes a first groove located that accommodates a first gasket, sets of matching threads on the first and second pieces. The interface section further accommodates a second gasket. In this multi-piece high-voltage insulator, the first material can have a first set of flexural, heat resistance, and electrical standoff characteristics suitable for a first environment, and the second material can have a second set of flexural, heat resistance and electrical standoff characteristics suitable for a second environment. |
FILED | Tuesday, April 13, 2021 |
APPL NO | 17/229487 |
ART UNIT | 2847 — Electrical Circuits and Systems |
CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 17/44 (20130101) H01B 17/305 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651945 | Kertesz et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Vilmos Kertesz (Oak Ridge, Tennessee); John F. Cahill (Knoxville, Tennessee) |
ABSTRACT | A system for the mass spectrometry analysis of an analyte includes a droplet ejection device, a spray head comprising a spray tip for ejecting the solvent as a spray, and a solvent delivery conduit for delivering solvent to the spray tip. The spray head includes a droplet inlet opening communicating with the surrounding atmosphere for receiving liquid droplets comprising the analyte. The droplet ejection device selectively ejects a liquid analyte droplet comprising the analyte through a surrounding atmosphere and the droplet inlet opening into a solvent flowing through the solvent delivery conduit. A method for the mass spectrometry analysis of an analyte is also disclosed. |
FILED | Monday, September 20, 2021 |
APPL NO | 17/480094 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/105 (20130101) H01J 49/145 (20130101) H01J 49/161 (20130101) H01J 49/165 (20130101) H01J 49/0445 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652330 | Lentine et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Yale University (New Haven, Connecticut) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Yale University (New Haven, Connecticut) |
INVENTOR(S) | Anthony L. Lentine (Albuquerque, New Mexico); Michael Gehl (Albuquerque, New Mexico); Peter Rakich (New Haven, Connecticut); Shai Gertler (New Haven, Connecticut); Nils Otterstrom (Albuquerque, New Mexico) |
ABSTRACT | An optical amplifier device employing a Mach-Zehnder Interferometer (MZI) that reduces the amount of residual pump power in the optical output of the amplifier is disclosed. The MZI amplifier employs two geometrically linear optical amplifier arms or two multi-spatial-mode racetrack optical amplifiers to amplify a signal with a pumping beam, with the signal output port having extremely low levels of residual pump power. The MZI optical amplifier is a silicon photonic integrated circuit, with all optical amplifiers, couplers, phase shifters, and optical attenuators formed of silicon photonic integrated circuit elements. The MZI optical amplifier may include one, two, or three MZI stages, and multiple MZI optical amplifiers may be used in parallel or sequentially to achieve higher overall signal gain or power. The MZI optical amplifier may employ Brillouin-scattering-based amplifiers, Raman-based integrated waveguide optical amplifiers, or Erbium-doped integrated waveguide optical amplifiers. |
FILED | Monday, November 16, 2020 |
APPL NO | 17/098577 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/30 (20130101) Original (OR) Class H01S 3/091 (20130101) H01S 3/0637 (20130101) H01S 3/2308 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652494 | Buckley et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Tektronix, Inc. (Beaverton, Oregon) |
ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); TEKTRONIX, INC. (Beaverton, Oregon) |
INVENTOR(S) | Brandon Walter Buckley (Walnut Creek, California); Ryan Douglas Muir (Livermore, California); Daniel G. Knierim (Beaverton, Oregon) |
ABSTRACT | Methods and devices for digitizing an analog repetitive signal using waveform averaging are described. An example method includes generating a discrete set of analog dither offset voltages, wherein at least two of the discrete set of analog dither offset voltages are different from each other, receiving the analog repetitive signal comprising multiple instances of a waveform, wherein the waveform has a waveform duration, generate a timing alignment to align each waveform of the analog repetitive signal and the corresponding analog dither offset voltage over the waveform duration, combining, based on the timing alignment, each waveform and the corresponding analog dither offset voltage over the waveform duration to produce an analog output signal, converting the analog output signal to a digital output signal, and producing, based on the timing alignment, a digital averaged signal based on averaging the multiple instances of the waveform in the analog output signal. |
FILED | Friday, December 17, 2021 |
APPL NO | 17/555226 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/124 (20130101) H03M 1/201 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 11647904 | Hu et al. |
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FUNDED BY |
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APPLICANT(S) | University Of Maryland, Baltimore (Baltimore, Maryland) |
ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
INVENTOR(S) | Fu-Ming Hu (Ellicott City, Maryland); Lynn G. Stansbury (Seattle, Washington); Colin F. Mackenzie (Pasadena, Maryland); Thomas M. Scalea (Baltimore, Maryland); Deborah M. Stein (Owings Mills, Maryland); Shiming Yang (Halethorpe, Maryland) |
ABSTRACT | A method and apparatus for monitoring collection of subject condition data is provided. The method includes receiving a value of a parameter of subject condition data and a value of a sample time, for each of a plurality of sample times. The method also includes storing the subject condition data in a data structure including a first field for holding data indicating a current sample time and a second field for holding data indicating the value of the parameter. The method also includes determining a time gap defined by a duration between the current sample time and a most recent sample time and determining whether the time gap exceeds a time gap threshold and causing an apparatus to perform remedial action. A method for presenting the subject condition data on a display is also provided. |
FILED | Monday, February 21, 2022 |
APPL NO | 17/676657 |
ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0006 (20130101) A61B 5/0008 (20130101) A61B 5/0022 (20130101) Original (OR) Class A61B 5/1113 (20130101) A61B 5/1455 (20130101) A61B 5/02055 (20130101) A61B 5/02405 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 10/60 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11647978 | Gao et al. |
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FUNDED BY |
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APPLICANT(S) | Cardiac Motion, LLC (Truckee, California); The Regents of The University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Xiaomeng Gao (Dublin, California); Xiaonan Jiang (Davis, California); Xiaoguang Liu (Davis, California); Dennis Matthews (Meadow Vista, California); Saul Schaefer (Davis, California) |
ABSTRACT | The present disclosure describes systems, methods, and devices to infer changes in pulmonary artery pressure in a subject using Doppler radar. A portable, non-invasive device for non-invasively measuring right ventricular cardiac motion that can be used in a subject's home can infer pulmonary artery pressure changes to increase patient compliance and mitigate the likelihood of heart decompensation. A mobile pulmonary artery pressure monitor can be especially useful to patients with congestive heart failure who are elderly, incapacitated, or do not have easy access to a clinic, doctor's office, or hospital. |
FILED | Tuesday, November 24, 2020 |
APPL NO | 17/102838 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/02 (20130101) A61B 8/04 (20130101) Original (OR) Class A61B 8/08 (20130101) A61B 8/488 (20130101) A61B 8/5207 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648200 | Chilkoti et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Ashutosh Chilkoti (Durham, North Carolina); Davoud Mozhdehi (Durham, North Carolina); Kelli M. Luginbuhl (Durham, North Carolina) |
ABSTRACT | Disclosed herein are conjugates including a fatty acid, a self-assembly domain, and a polypeptide, where the conjugates have phase transition behavior. Further disclosed are methods of using the conjugates to treat disease, methods of delivering an agent, and methods of preparing the conjugates. |
FILED | Friday, January 12, 2018 |
APPL NO | 16/477229 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 47/42 (20130101) Peptides C07K 14/78 (20130101) C07K 2319/033 (20130101) C07K 2319/90 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/1029 (20130101) C12N 2501/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) Enzymes C12Y 203/01097 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11648559 | Mao |
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FUNDED BY |
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APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
INVENTOR(S) | Leidong Mao (Athens, Georgia) |
ABSTRACT | A variety of devices and methods are provided for separating or enriching circulating tumor cells in a biological sample such as whole blood. In some aspects, the devices are multi-stage devices including at least (i) a filtering stage, (ii) a sheath flow stage for ferrohydrodynamic separation of magnetically labelled white blood cells, and (iii) a focusing stage for marker-independent and size-independent focusing of magnetically labeled particles so as to separate or enrich unlabeled rare cells in the biological sample. The devices and methods are, in some aspects, capable of high throughput in excess of 6 milliliters per hour while achieving high separation (>95%) of the unlabeled rare cells. |
FILED | Saturday, August 04, 2018 |
APPL NO | 16/636517 |
ART UNIT | 3653 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 3/502776 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/0681 (20130101) B01L 2300/0864 (20130101) B01L 2300/0883 (20130101) B01L 2400/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649160 | Painter et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annandale, Virginia) |
ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
FILED | Monday, November 02, 2020 |
APPL NO | 17/087316 |
ART UNIT | 2826 — Semiconductors/Memory |
CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 3/0029 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 13/025 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649320 | Tropp et al. |
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APPLICANT(S) | Joshua Tropp (Hattiesburg, Mississippi); Douglas V. Amato (Hattiesburg, Mississippi); Derek L. Patton (Hattiesburg, Mississippi); Jason D. Azoulay (Hattiesburg, Mississippi) |
ASSIGNEE(S) | University of Southern Mississippi (Hattiesburg, Mississippi) |
INVENTOR(S) | Joshua Tropp (Hattiesburg, Mississippi); Douglas V. Amato (Hattiesburg, Mississippi); Derek L. Patton (Hattiesburg, Mississippi); Jason D. Azoulay (Hattiesburg, Mississippi) |
ABSTRACT | The present invention provides novel polymer compounds and methods and processes for polymerizing and synthesizing the new polymers by post-modifying conjugated polymers bearing unsaturated functionalities. The post-modifications are facilitated by light-mediated initiators, thermal initiators, redox-based initiators, small molecule-based initiators, or a combination thereof. Syntheses and post-modifications are carried out to high conversion via thiol-ene “click” chemistry-based mechanisms. The products comprise monomeric, oligomeric, and polymeric materials with easily-accessible pendant functionalities which impart new, distinct, and/or improved properties. |
FILED | Monday, September 23, 2019 |
APPL NO | 16/579694 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) C08G 61/126 (20130101) Original (OR) Class C08G 2261/18 (20130101) C08G 2261/78 (20130101) C08G 2261/124 (20130101) C08G 2261/145 (20130101) C08G 2261/228 (20130101) C08G 2261/1412 (20130101) C08G 2261/1426 (20130101) C08G 2261/3142 (20130101) C08G 2261/3223 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649447 | You et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Lingchong You (Durham, North Carolina); Anna Lee (Durham, North Carolina); Zhuojun Dai (Durham, North Carolina) |
ABSTRACT | The present disclosure relates to compositions, systems, and methods for the production of biomolecules using microorganisms. In particular, the present disclosure provides biomolecule production platforms that include genetically engineered microorganisms with genetic circuits functionally coupled to microcapsules formed from materials that are responsive to culture conditions. The biomolecule production platforms disclosed herein facilitate the efficient and robust production, purification, and/or analysis of any biomolecule-of-interest. |
FILED | Tuesday, June 12, 2018 |
APPL NO | 16/621615 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 25/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) Original (OR) Class C12N 15/70 (20130101) C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649548 | Pyun et al. |
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APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
INVENTOR(S) | Dong-Chul Pyun (Tucson, Arizona); Richard S. Glass (Tucson, Arizona); Dennis Lichtenberger (Tucson, Arizona); William Brezinski (Tucson, Arizona); Kayla Clary (Tucson, Arizona); Metin Karayilan (Tucson, Arizona) |
ABSTRACT | Metallopolymers composed of polymers and catalytically active diiron-disulfide ([2Fe-2S]) complexes are described herein. [FeFe]-hydrogenase mimics have been synthesized and used to initiate polymerization of various monomers to generate metallopolymers containing active [2Fe-2S] sites which serve as catalysts for a hydrogen evolution reaction (HER). Vinylic monomers with polar groups provided water solubility relevant for large scale hydrogen production, leveraging the supramolecular architecture to improve catalysis. Metallopolymeric electrocatalysts displayed high turnover frequency and low overpotential in aqueous media as well as aerobic stability. Metallopolymeric photocatalysts incorporated P3HT ligands to serve as a photosensitizer to promote photoinduced electron transfer to the active complex. |
FILED | Monday, December 11, 2017 |
APPL NO | 16/466571 |
ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/165 (20130101) B01J 2531/842 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/02 (20130101) Original (OR) Class C25B 1/55 (20210101) C25B 11/048 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11649710 | Alali et al. |
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FUNDED BY |
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APPLICANT(S) | Eden GeoPower, Inc. (Somerville, Massachusetts) |
ASSIGNEE(S) | Eden GeoPower, Inc. (Somerville, Massachusetts) |
INVENTOR(S) | Ammar Alali (Somerville, Massachusetts); Mehrdad Mehrvand (Somerville, Massachusetts) |
ABSTRACT | Downhole tools, systems, and methods for electric-based fracturing are disclosed. A downhole tool for electric-based fracturing may include an outer enclosure, an insulator chamber disposed at least partially within the enclosure, and an electrode disposed at least partially within the insulator chamber. The electrode may extend out from the insulator chamber and the enclosure, and may be configured to transfer electric energy to an exterior environment surrounding the downhole tool. The insulator chamber may be configured to thermally and electrically insulate at least a portion of the electrode from the exterior environment. |
FILED | Thursday, July 15, 2021 |
APPL NO | 17/376809 |
ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 17/028 (20130101) E21B 43/26 (20130101) Original (OR) Class E21B 43/2401 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650028 | Howell et al. |
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FUNDED BY |
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APPLICANT(S) | BRIGHAM YOUNG UNIVERSITY (Provo, Utah) |
ASSIGNEE(S) | BRIGHAM YOUNG UNIVERSITY (Provo, Utah) |
INVENTOR(S) | Larry L. Howell (Provo, Utah); Spencer P. Magleby (Provo, Utah); David C. Morgan (Provo, Utah); Terri Bateman (Provo, Utah); Jeffrey E. Niven (Provo, Utah); Alex Avila (Provo, Utah); Erica Crampton (Provo, Utah); Kyler Tolman (Provo, Utah); Jacob Greenwood (Provo, Utah); Peter Schleede (Provo, Utah) |
ABSTRACT | An example barrier can be switchable between an at least partially collapsed state and at least partially expanded state (e.g., a deployed state). For example, the barrier can be formed from a continuous sheet and a plurality of rigid sections (e.g., rigid panels) attached or incorporated into the continuous sheet. The barrier can also include a plurality of hinges, such as hinge lines, between the panels that are formed from the continuous sheet. The hinges enable the barrier to be rigid foldable (e.g., the hinges can fold and unfold while the rigid sections remain stiff and rigid) between the expanded and collapsed states. |
FILED | Wednesday, December 01, 2021 |
APPL NO | 17/539436 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Additional Work, Such as Equipping Roads or the Construction of Platforms, Helicopter Landing Stages, Signs, Snow Fences, or the Like E01F 13/02 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/06 (20130101) E06B 2009/007 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/04 (20130101) F41H 5/06 (20130101) Original (OR) Class F41H 5/013 (20130101) F41H 5/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650148 | Pate |
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FUNDED BY |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | Brooks Hart Pate (Charlottesville, Virginia) |
ABSTRACT | A chiral molecule can be defined as a molecule that has a non-superimposable mirror image. These mirror images can be referred to as enantiomers. The enantiomers generally have the same set of bond lengths and bond angles in their three-dimensional geometry. Apparatus and techniques described herein can be used to perform analysis of chiral molecules using cavity-enhanced molecular rotational spectroscopy. A sample cell can define a resonant cavity, and a sample introduction port can provide pulse-jet injection of an analyte molecule and a chiral tag to allow analysis of a complex comprising the analyte and chiral tag. |
FILED | Friday, January 07, 2022 |
APPL NO | 17/647364 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/16 (20130101) G01J 3/30 (20130101) G01J 3/447 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3586 (20130101) Original (OR) Class G01N 22/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 23/20 (20130101) H01J 23/207 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650204 | Park et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
INVENTOR(S) | Young Geun Park (Ann Arbor, Michigan); Byunghoon Ryu (Ann Arbor, Michigan); Xiaogan Liang (Ann Arbor, Michigan); Katsuo Kurabayashi (Ann Arbor, Michigan) |
ABSTRACT | Provided herein are systems and methods for performing assays. In particular, provided herein are systems and methods for performing sensitive and rapid immunoassays. |
FILED | Monday, April 23, 2018 |
APPL NO | 16/607800 |
ART UNIT | 1677 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 2333/715 (20130101) Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652179 | Kotru et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
ASSIGNEE(S) | The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
INVENTOR(S) | Sushma Kotru (Tuscaloosa, Alabama); Vaishali Batra (Tuscaloosa, Alabama) |
ABSTRACT | Embodiments disclosed herein facilitates the monitoring of direct ultraviolet B (UVB) radiation exposure by a person via a system having a sensor (such as Lanthanum doped lead zirconate titanate (PLZT) thin-film sensors or other ferroelectric-based sensors) sensitive to UVB radiation. The system beneficially provides current real-time dosage information associated with Vitamin D production by the person as well as real-time indication of safe exposure and/or harmful exposure to current UVB radiation conditions while also, in some embodiments, takes into consideration a person's age, skin type and sensitivity, body surface area exposed. |
FILED | Tuesday, January 19, 2021 |
APPL NO | 17/151781 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) G01J 1/0219 (20130101) G01J 1/0238 (20130101) G01J 1/429 (20130101) G01J 5/10 (20130101) G01J 5/34 (20130101) G01J 5/046 (20130101) G01J 2001/0257 (20130101) G01J 2001/446 (20130101) G01J 2001/4266 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) H01L 31/032 (20130101) Original (OR) Class H01L 31/108 (20130101) H01L 31/109 (20130101) H01L 31/0465 (20141201) H01L 31/022475 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652183 | Zheng et al. |
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FUNDED BY |
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APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
INVENTOR(S) | Bob Yi Zheng (Houston, Texas); Hangqi Zhao (Houston, Texas); Benjamin Cerjan (Houston, Texas); Mehbuba Tanzid (Houston, Texas); Peter J. Nordlander (Houston, Texas); Nancy J. Halas (Houston, Texas) |
ABSTRACT | An infrared photodetector includes: a p-type and highly-doped silicon substrate; a metal structure disposed on the silicon substrate; a first electric contact to the silicon substrate; and a second electric contact to the metal structure. |
FILED | Friday, June 12, 2020 |
APPL NO | 16/899759 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/20 (20130101) G01J 2005/0077 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/101 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652187 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
INVENTOR(S) | Seok Kim (Champaign, Illinois); Moonsub Shim (Savoy, Illinois); Jun Kyu Park (Champaign, Illinois); Hohyun Keum (Champaign, Illinois); Yiran Jiang (Freemont, California) |
ABSTRACT | The present disclosure describes one or more embodiment of a method for creating a patterned quantum dot layer. The method includes bringing a patterning stamp in contact with a layer of quantum dots disposed on a substrate, the patterning stamp comprising a patterned photoresist layer disposed on an elastomer layer, such that a portion of the quantum dots in contact with the patterned photoresist layer adheres to the patterning stamp, the portion of the quantum dots being adhered quantum dots. The method also includes peeling the patterning stamp from the substrate with a peeling speed larger than a pre-determined peeling speed to remove the adhered quantum dots from the substrate. A remaining portion of the quantum dots forms a patterned quantum dot layer on the substrate. |
FILED | Tuesday, September 14, 2021 |
APPL NO | 17/474332 |
ART UNIT | 2822 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) Original (OR) Class H01L 33/505 (20130101) H01L 33/507 (20130101) H01L 2933/0041 (20130101) H01L 2933/0058 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652188 | Monavarian et al. |
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FUNDED BY |
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APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
ASSIGNEE(S) | |
INVENTOR(S) | Morteza Monavarian (Albuquerque, New Mexico); Daniel Feezell (Albuquerque, New Mexico); Behnam Abaie (Albuquerque, New Mexico); Arash Mafi (Albuquerque, New Mexico); Saadat Mishkat-Ul-Masabih (Albuquerque, New Mexico) |
ABSTRACT | A method of forming and a random Distributed Bragg Reflector (DBR) is disclosed. The random DBR includes a substrate and a plurality of alternating layers of lattice-matched nanoporous GaN (NP-GaN) and GaN formed on a top surface of the substrate, wherein at least one of the alternating layers has a thickness of λ/4n and an adjacent one of the alternating layers does not have a thickness of λ/4n, wherein λ is a wavelength of incident radiation and n is the refractive index of a particular layer of the plurality of alternating layers. |
FILED | Wednesday, October 28, 2020 |
APPL NO | 17/083242 |
ART UNIT | 2816 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/10 (20130101) Original (OR) Class H01L 33/32 (20130101) H01L 33/46 (20130101) H01L 33/0075 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/04253 (20190801) H01S 5/18361 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652556 | Alishahi et al. |
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FUNDED BY |
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APPLICANT(S) | University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
INVENTOR(S) | Fatemeh Alishahi (Los Angeles, California); Yinwen Cao (Los Angeles, California); Ahmad Fallahpour (Los Angeles, California); Amirhossein Mohajerin-Ariaei (Los Angeles, California); Alan E. Willner (Los Angeles, California) |
ABSTRACT | A method for all-optical reduction of inter-channel crosstalk for spectrally overlapped optical signals for maximizing utilization of an available spectrum includes receiving a plurality of spectrally overlapped optical signals modulated with data. The method further includes generating conjugate copies of each of the plurality of optical signals using non-linear optics. The method further includes selecting the conjugate copies and adjusting an amplitude, a phase, and a delay of the conjugate copies. The method further includes performing inter-channel interference (ICI) compensation on the spectrally overlapped optical signals in an optical domain by adding the adjusted conjugate copies to the spectrally overlapped optical signals. |
FILED | Friday, March 08, 2019 |
APPL NO | 16/979157 |
ART UNIT | 2637 — Optical Communications |
CURRENT CPC | Transmission H04B 10/615 (20130101) H04B 10/697 (20130101) Original (OR) Class H04B 10/2543 (20130101) H04B 10/2557 (20130101) Multiplex Communication H04J 14/0201 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652557 | Zheng et al. |
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FUNDED BY |
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APPLICANT(S) | Yahong Rosa Zheng (Rolla, Missouri); Weimin Duan (San Diego, California); Chengshan Xiao (Rolla, Missouri) |
ASSIGNEE(S) | UNIVERSITY OF MISSOURI (Columbia, Missouri) |
INVENTOR(S) | Yahong Rosa Zheng (Rolla, Missouri); Weimin Duan (San Diego, California); Chengshan Xiao (Rolla, Missouri) |
ABSTRACT | Aspects of the present disclosure include methods for communication using a MIMO channel, such as an acoustic channel for underwater communication. An acoustic receiver may receive a signal comprising information encoded in at least one transmitted symbol. Using a two-layer iterative process, the at least one transmitted symbol is estimated. The first layer of the two-layer process uses iterative exchanges of soft-decisions between an adaptive turbo equalizer and a MAP decoder. The second layer of the two-layer process uses a data-reuse procedure that adapts an equalizer vector of both a feedforward filter and a serial interference cancellation filter of the adaptive turbo equalizer using a posteriori soft decisions of the at least one transmitted symbol. After a plurality of iterations, a hard decision of the bits encoded on the at least one transmitted symbol is output from the MAP decoder. |
FILED | Tuesday, March 17, 2020 |
APPL NO | 16/821816 |
ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Transmission H04B 11/00 (20130101) H04B 13/02 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/03057 (20130101) H04L 27/0008 (20130101) H04L 2025/03426 (20130101) H04L 2025/03636 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 11651231 | Hoskins et al. |
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APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
INVENTOR(S) | Brian Douglas Hoskins (North Bethesda, Maryland); Mark David Stiles (Silver Spring, Maryland); Matthew William Daniels (Bethesda, Maryland); Advait Madhavan (Silver Spring, Maryland); Gina Cristina Adam (Washington, District of Columbia) |
ABSTRACT | A quasi-systolic array includes: a primary quasi-systolic processor; an edge row bank and edge column bank of edge quasi-systolic processors; and an interior bank of interior quasi-systolic processors. The primary quasi-systolic processor, edge quasi-systolic processor, and interior quasi-systolic processor independently include a quasi-systolic processor and are disposed and electrically connected in rows and columns in the quasi-systolic array. |
FILED | Monday, March 02, 2020 |
APPL NO | 16/806121 |
ART UNIT | 2182 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) G06F 2207/4824 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/10 (20130101) Original (OR) Class G06N 3/0635 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651949 | Leibrandt et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
INVENTOR(S) | David Ray Leibrandt (Superior, Colorado); David Brian Hume (Boulder, Colorado); Roger Charles Brown (Atlanta, Georgia); Jeffrey Aaron Sherman (Louisville, Colorado) |
ABSTRACT | A spherical ion trap includes a substrate and an ion aperture; two RF electrodes in electrostatic communication with an ion trapping region; RF ground electrodes in electrostatic communication with the ion trapping region; and the ion trapping region bounded by opposing RF electrodes and the RF ground electrodes, such that: the ion trapping region is disposed within the ion aperture and receives ions that are selectively trapped in the ion trapping region in response to receipt of DC and RF voltages by the RF electrodes, and receipt of the DC voltages by RF ground electrodes, and the first RF electrode, the second RF electrode, the RF ground electrodes, and the ion trapping region are disposed in the same plane within the ion aperture. |
FILED | Tuesday, February 01, 2022 |
APPL NO | 17/590690 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/424 (20130101) Original (OR) Class H01J 49/4265 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11652556 | Alishahi et al. |
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FUNDED BY |
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APPLICANT(S) | University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
INVENTOR(S) | Fatemeh Alishahi (Los Angeles, California); Yinwen Cao (Los Angeles, California); Ahmad Fallahpour (Los Angeles, California); Amirhossein Mohajerin-Ariaei (Los Angeles, California); Alan E. Willner (Los Angeles, California) |
ABSTRACT | A method for all-optical reduction of inter-channel crosstalk for spectrally overlapped optical signals for maximizing utilization of an available spectrum includes receiving a plurality of spectrally overlapped optical signals modulated with data. The method further includes generating conjugate copies of each of the plurality of optical signals using non-linear optics. The method further includes selecting the conjugate copies and adjusting an amplitude, a phase, and a delay of the conjugate copies. The method further includes performing inter-channel interference (ICI) compensation on the spectrally overlapped optical signals in an optical domain by adding the adjusted conjugate copies to the spectrally overlapped optical signals. |
FILED | Friday, March 08, 2019 |
APPL NO | 16/979157 |
ART UNIT | 2637 — Optical Communications |
CURRENT CPC | Transmission H04B 10/615 (20130101) H04B 10/697 (20130101) Original (OR) Class H04B 10/2543 (20130101) H04B 10/2557 (20130101) Multiplex Communication H04J 14/0201 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 11649991 | Jacobs |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Bryson Jacobs (Quaker Hill, Connecticut) |
ABSTRACT | A thermoacoustic refrigeration assembly includes a resonating tube having a first end and a second end; a first mechanical oscillator at the first end; a second mechanical oscillator at the second end; and a thermoacoustic stack sandwich disposed along a length of the resonating tube through which gas travels. The stack sandwich includes a first outboard heat exchanger on a first side of the stack sandwich facing the first mechanical oscillator, a second outboard heat exchanger on a second side of the stack sandwich facing the second mechanical oscillator, and a center heat exchanger disposed between the first outboard heat exchanger and the second outboard heat exchanger. |
FILED | Thursday, May 05, 2022 |
APPL NO | 17/737063 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 9/145 (20130101) Original (OR) Class F25B 2309/1407 (20130101) F25B 2309/1412 (20130101) F25B 2309/1413 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650168 | Karns et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
INVENTOR(S) | Duane Clifford Karns (Mays Landing, New Jersey); James Christopher Weatherall (Linwood, New Jersey); Jeffrey Brian Barber (Vineland, New Jersey); Barry Thomas Smith (Egg Harbor City, New Jersey); Zachary J. Landicini (Vineland, New Jersey) |
ABSTRACT | A method of using a resonant cavity for measuring a complex permittivity ε and identifying of a sample (solid or liquid) of microliter volume size includes using a network analyzer to measure over a defined millimeter wave frequency range, a first resonance frequency at a cavity resonance mode, and calculating an unloaded quality factor of an enclosed resonant waveguide cavity of a defined internal dimensions, placing a sample on a surface of a bottom wall of the resonant waveguide cavity and measure a second resonance frequency and calculating a loaded quality factor; determining, a resonance frequency shift Δf=(fs−fo), determining a complex permittivity ε of the sample according to the resonance frequency shift Δf, the loaded quality factor, the unloaded quality factor and the defined internal dimensions; and identifying the sample using a database through the complex permittivity ε. |
FILED | Friday, September 18, 2020 |
APPL NO | 17/025600 |
ART UNIT | 2866 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/00 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650310 | Vemury |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Arun Vemury (North Bethesda, Maryland) |
ABSTRACT | In an example, information related to a user of a mobile device and to an item associated with the user is received from a network. Based on the information a screening threshold is determined. The screening threshold is communicated to an electronic physical screening device and a direction instruction, indicating a location of a physical screening area corresponding to the electronic physical screening device, is communicated to the mobile device. The direction instruction causes the mobile device to display a direction information, directing the user to the physical screening area, for a physical screening in accordance with the threshold. |
FILED | Thursday, August 12, 2021 |
APPL NO | 17/401028 |
ART UNIT | 2685 — Selective Communication |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/887 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Wireless Communication Networks H04W 4/029 (20180201) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 11649337 | Wohl et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Christopher J Wohl (Suffolk, Virginia); Samantha I Applin (Hampton, Virginia); Hannes Schniepp (Williamsburg, Virginia); Bryce L Horvath (Virginia Beach, Virginia) |
ABSTRACT | A method of recycling a polymer structure includes converting a first polymer structure into feedstock. The first polymer structure comprises particles that are bonded to one another by chemical click bonds to form a first shape. The first polymer structure is converted into feedstock particles by breaking the click bonds. The feedstock particles are formed into a second shape, and the feedstock particles are chemically click-bonded together to form a second polymer structure having a second shape. Breaking the click bonds may include heating the particles. The structures may be formed by causing first particles having dienes to chemically bond to dienophiles of second particles. |
FILED | Thursday, March 26, 2020 |
APPL NO | 16/831163 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 290/064 (20130101) C08F 2810/20 (20130101) C08F 2810/30 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/12 (20130101) Original (OR) Class C08J 2363/00 (20130101) C08J 2379/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650151 | Bathel et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Brett F. Bathel (Yorktown, Virginia); Joshua M. Weisberger (Newport News, Virginia) |
ABSTRACT | Light is projected through a grid (e.g., a Ronchi ruling) and onto a background, where it forms an image of the ruling. The light from this projected image is then reflected back onto the same grid, with a polarizing refractor (e.g., a Rochon polarizing prism) imparting a small offset between the projected and reflected light, and then on to an imaging camera. Thus, a separate source and cutoff grid is not needed, resulting in a focusing schlieren system that is compact and easy to construct and align. In some embodiments, translation of the polarizing refractor along the instrument axis provides a sensitivity adjustment of the resulting schlieren images. Manipulation of the polarization state of the light through the system allows the projected and reflected light to be coincident, maintaining a small footprint for the system, which can be mounted to the front of the imaging camera. |
FILED | Thursday, September 30, 2021 |
APPL NO | 17/490521 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2513 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/455 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 27/286 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 11650652 | Ardanaz et al. |
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FUNDED BY |
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APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
ASSIGNEE(S) | INTEL CORPORATION (Santa Clara, California) |
INVENTOR(S) | Federico Ardanaz (Hillsboro, Oregon); Jonathan M. Eastep (Portland, Oregon); Richard J. Greco (West Linn, Oregon); Ramkumar Nagappan (Chandler, Arizona); Alan B. Kyker (Winters, California) |
ABSTRACT | Apparatus, systems, and methods provide an interface between a plurality of hardware resources of a node and a power manager. The interface is configured to define one or more resource groups to expose to the power manager for power measurement and control, assign the plurality of hardware resources to the one or more resource groups, and provide a power allowance to each resource group. |
FILED | Thursday, June 24, 2021 |
APPL NO | 17/357479 |
ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 1/325 (20130101) Original (OR) Class G06F 1/3287 (20130101) G06F 1/3293 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11651973 | Nah et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Jae-Woong Nah (Closter, New Jersey); Evan Colgan (Yorktown Heights, New York); Robert P. Kuder, II (Hopewell Junction, New York); James L. Speidell (Poughquag, New York); Bucknell C. Webb (Ossining, New York) |
ABSTRACT | A method and apparatus for bonding a processor wafer with a microchannel wafer/glass manifold to form a bonded wafer structure are provided. A glass fixture is also provided for protecting C4 solder bumps on chips disposed on the processor wafer. When the glass fixture is positioned on the processor wafer, posts extending from the glass fixture contact corresponding regions on the processor wafer devoid of C4 solder bumps, so that the glass fixture protects the C4 solder bumps during wafer bonding. The method involves positioning the processor wafer/glass fixture and the microchannel wafer/glass manifold in a metal fixture having one or more alignment structures adapted to engage corresponding alignment elements formed in the processor wafer, glass fixture and/or glass manifold. The metal fixture secures the wafer components in place and, after melting solder pellets disposed between the processor wafer/glass fixture and microchannel wafer/glass manifold, a bonded wafer structure is formed. |
FILED | Friday, May 08, 2020 |
APPL NO | 16/869744 |
ART UNIT | 2812 — Semiconductors/Memory |
CURRENT CPC | Electric Digital Data Processing G06F 1/20 (20130101) G06F 2200/201 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4882 (20130101) Original (OR) Class H01L 21/6835 (20130101) H01L 21/67092 (20130101) H01L 23/367 (20130101) H01L 23/473 (20130101) H01L 23/562 (20130101) H01L 23/49816 (20130101) H01L 2221/6834 (20130101) H01L 2224/94 (20130101) H01L 2224/11002 (20130101) H01L 2224/11009 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 11647765 | Ulmasov et al. |
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FUNDED BY |
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APPLICANT(S) | COVERCRESS INC. (St. Louis, Missouri); BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (Normal, Illinois); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
ASSIGNEE(S) | COVERCRESS INC. (St. Louis, Missouri); BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (Normal, Illinois); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
INVENTOR(S) | Tim Ulmasov (St. Louis, Missouri); Gary Hartnell (St. Peters, Missouri); John C. Sedbrook (Bloomington, Illinois); Michael David Marks (Roseville, Minnesota); Ratan Chopra (St. Louis, Missouri); Maliheh Esfahanian (Stanford, California) |
ABSTRACT | Pennycress seed, seed lots, and seed meal having reduced fiber content and improved suitability for use in producing animal feed are provided. |
FILED | Friday, December 10, 2021 |
APPL NO | 17/643730 |
ART UNIT | 1662 — Plants |
CURRENT CPC | Fodder A23K 10/30 (20160501) Original (OR) Class A23K 20/158 (20160501) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 11647869 | Wesley |
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FUNDED BY |
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APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Randall Wesley (Chicago, Illinois) |
ABSTRACT | A bench assembly can be for use in a bathtub for showering. The bench assembly can comprise a frame that is configured to sit within a bathtub. A bench can be coupled to the frame. A pivotable platform assembly can comprise a platform support structure pivotably coupled to the frame and a platform coupled to the platform support structure. The pivotable platform assembly can be configured to bias against an upper rim of the bathtub. |
FILED | Wednesday, November 18, 2020 |
APPL NO | 16/951326 |
ART UNIT | 3754 — Fluid Handling and Dispensing |
CURRENT CPC | Chairs; Sofas; Beds A47C 7/14 (20130101) Sanitary Equipment Not Otherwise Provided for; Toilet Accessories A47K 3/122 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
US 11649031 | Pascucilla |
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FUNDED BY |
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APPLICANT(S) | East Shore District Health Department (Branford, Connecticut) |
ASSIGNEE(S) | East Shore District Health Department (Branford, Connecticut) |
INVENTOR(S) | Michael A. Pascucilla (Guilford, Connecticut) |
ABSTRACT | A solar electric pump-out boat for removing human waste. The pump-out boat may include a boat hull, wherein the boat hull may include a bow, a stern, and a self-draining sole disposed therein. The pump-out boat may further include a holding tank disposed within the hull underneath the self-draining sole for collecting waste. The pump-out boat may further include a console disposed approximately center of, and on a top surface of the self-draining sole. The pump-out boat may further include a solar panel for absorbing sunlight to convert into electrical power. The pump-out boat may further include a pump disposed within the console. The pump-out boat may further include a battery connected to a motor, the pump, and the solar panel, such that the solar panel charges the battery to provide the electrical power to operate the pump and the motor. |
FILED | Thursday, October 22, 2020 |
APPL NO | 17/077151 |
ART UNIT | 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 17/02 (20130101) B63B 29/16 (20130101) B63B 2017/026 (20130101) Marine Propulsion or Steering B63H 21/17 (20130101) B63H 2021/171 (20130101) Auxiliaries on Vessels B63J 4/006 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 11647978 | Gao et al. |
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FUNDED BY |
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APPLICANT(S) | Cardiac Motion, LLC (Truckee, California); The Regents of The University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Xiaomeng Gao (Dublin, California); Xiaonan Jiang (Davis, California); Xiaoguang Liu (Davis, California); Dennis Matthews (Meadow Vista, California); Saul Schaefer (Davis, California) |
ABSTRACT | The present disclosure describes systems, methods, and devices to infer changes in pulmonary artery pressure in a subject using Doppler radar. A portable, non-invasive device for non-invasively measuring right ventricular cardiac motion that can be used in a subject's home can infer pulmonary artery pressure changes to increase patient compliance and mitigate the likelihood of heart decompensation. A mobile pulmonary artery pressure monitor can be especially useful to patients with congestive heart failure who are elderly, incapacitated, or do not have easy access to a clinic, doctor's office, or hospital. |
FILED | Tuesday, November 24, 2020 |
APPL NO | 17/102838 |
ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/02 (20130101) A61B 8/04 (20130101) Original (OR) Class A61B 8/08 (20130101) A61B 8/488 (20130101) A61B 8/5207 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 11650018 | Roberge |
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FUNDED BY |
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APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
INVENTOR(S) | Gary D. Roberge (Tolland, Connecticut) |
ABSTRACT | A heat exchanger duct includes a wall having ends spaced along a central axis. An inlet manifold is positioned within a downstream portion of the duct at a radially outward location. An outlet manifold is positioned within an upstream portion of the duct at a radially outward location. At least one of the inlet and outlet manifolds extend at least 10 degrees around the circumference of the duct. A central manifold is disposed between the inlet and outlet manifolds, and radially inwardly of the inlet and outlet manifolds. Heat exchanger entrance elements extend radially inward from the inlet manifold to the central manifold, and heat exchanger exit elements extend radially outward from the central manifold to the outlet manifold. A gas turbine engine is also disclosed. |
FILED | Friday, February 07, 2020 |
APPL NO | 16/784630 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/10 (20130101) F28F 9/22 (20130101) F28F 9/027 (20130101) Original (OR) Class F28F 27/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 11650356 | Starkovich et al. |
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FUNDED BY |
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APPLICANT(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
INVENTOR(S) | John A. Starkovich (Redondo Beach, California); Edward M. Silverman (Encino, California) |
ABSTRACT | A high-performance optical absorber is provided having a texturized base layer. The base layer has one or more of a polymer film and a polymer coating. A surface layer is located above and immediately adjacent to the base layer and the surface layer joined to the base layer. The surface layer comprises a plasma-functionalized, non-woven carbon nanotube (CNT) sheet, wherein the base layer texturization comprises one or more of substantially rectangular ridges, substantially triangular ridges, substantially pyramidal ridges, and truncated, substantially pyramidal ridges. The CNT sheet has a thickness greater than or equal to 10×λ, where λ is the wavelength of the incident light. In certain embodiments the base layer has a height above the surface layer greater than or equal to 10×λ, where λ is the wavelength of the incident light. |
FILED | Monday, September 19, 2022 |
APPL NO | 17/947375 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/0074 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Optical Elements, Systems, or Apparatus G02B 5/003 (20130101) Original (OR) Class G02B 2207/101 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 16, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230516.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page