FedInvent™ Patents

Patent Details for Tuesday, May 23, 2023 

This page was updated on Saturday, June 10, 2023 at 02:31 AM GMT

Department of Health and Human Services (HHS) 

US 11653834 Hillman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Non-Profit Organization (NPO)
Wallace H Coulter Foundation (WHCF)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Elizabeth Marjorie Clare Hillman (New York, New York);  Sean A. Burgess (New York, New York)
ABSTRACT Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM).
FILED Tuesday, August 31, 2021
APPL NO 17/462824
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0064 (20130101) Original (OR) Class
A61B 5/0066 (20130101)
A61B 5/0071 (20130101)
A61B 5/0073 (20130101)
A61B 5/0075 (20130101)
A61B 5/0088 (20130101)
A61B 5/444 (20130101)
A61B 5/445 (20130101)
A61B 2562/0238 (20130101)
A61B 2562/0242 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/42 (20130101)
G01J 3/457 (20130101)
G01J 3/2889 (20130101)

Optical Elements, Systems, or Apparatus
G02B 23/2476 (20130101)
G02B 26/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11653839 Zharov
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) BioVentures, LLC (Little Rock, Arkansas)
ASSIGNEE(S) BioVentures, LLC (Little Rock, Arkansas)
INVENTOR(S) Vladimir Pavlovich Zharov (Little Rock, Arkansas)
ABSTRACT A fractionated photoacoustic flow cytometry (PAFC) system and methods for the in vivo detection of target objects in biofluidic systems (e.g., blood, lymph, urine, or cerebrospinal fluid) of a living organism is described. The fractionated system includes a fractionated laser system, a fractionated optical system, a fractionated acoustic system, and combinations thereof. The fractionated laser system includes at least one laser or laser array for pulsing a target object within the circulatory vessel with fractionated focused laser beams. The fractionated optical system separates one or several laser beams into multiple beams in a spatial configuration on the skin above the circulatory vessel of the living organism. The fractionated acoustic system includes multiple focused ultrasound transducers for receiving photoacoustic signals emitted by the target object in response to the fractionated laser beams.
FILED Wednesday, February 24, 2021
APPL NO 17/184284
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0095 (20130101) Original (OR) Class
A61B 8/4461 (20130101)
A61B 8/4477 (20130101)
A61B 2560/04 (20130101)
A61B 2562/0204 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1056 (20130101)
G01N 15/1434 (20130101)
G01N 15/1459 (20130101)
G01N 15/1463 (20130101)
G01N 15/1475 (20130101)
G01N 2015/1006 (20130101)
G01N 2015/1062 (20130101)
G01N 2015/1075 (20130101)
G01N 2015/1438 (20130101)
G01N 2015/1477 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11653851 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Jin Hyung Lee (Palo Alto, California);  Hyun Joo Lee (Stanford, California);  Andrew J. Weitz (Stanford, California)
ABSTRACT Provided herein are methods for analyzing in vivo a brain circuit. A method of the present disclosure may include using optogenetics to stimulate a first region of a brain of an individual, in conjunction with functional magnetic resonance imaging (fMRI) of different regions of the brain to determine a dynamic functional connection between individual neurons of the first region and a second region of the brain. The method may further include identifying a third region of the brain, the neurons of which region mediate the dynamic functional connection between the first and second regions.
FILED Wednesday, November 30, 2016
APPL NO 15/781688
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class
A61B 5/0059 (20130101)
A61B 5/369 (20210101)
A61B 5/377 (20210101)
A61B 5/4064 (20130101)
A61B 2503/42 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/0622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11653899 Sawyer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Daniel P. Sawyer (Pasadena, California);  Arash Farhadi (Pasadena, California);  Avinoam D. Bar-Zion (Pasadena, California);  Mikhail Shapiro (Pasadena, California)
ABSTRACT The application of a step function increase in acoustic pressure during ultrasound imaging using gas vesicle contrast, along with capturing successive frames of ultrasound imaging and extracting time-series vectors for pixels of the frames, allows for improved imaging down to even the cell level. Template vectors can be used to implement signal separation of the time-series vectors to improve detection.
FILED Tuesday, January 07, 2020
APPL NO 16/736581
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/481 (20130101)
A61B 8/5207 (20130101) Original (OR) Class
A61B 8/5246 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654110 Elfar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) UNIVERSITY OF ROCHESTER (Rochester, New York)
ASSIGNEE(S) UNIVERSITY OF ROCHESTER (Rochester, New York)
INVENTOR(S) John Elfar (Rochester, New York);  Kuang-Ching Tseng (Rochester, New York);  Mark Noble (Brighton, New York)
ABSTRACT Provided herein are methods of treating a peripheral nerve injury in a subject. The methods include administering to the subject at or near the site of the peripheral nerve injury an effective amount of a composition comprising an agent that promotes remyelination of the peripheral nerve. Also provided are methods of determining whether a peripheral nerve injury has a capacity for recovery. The methods include selecting a subject with a peripheral nerve injury, administering to the subject a first dose of a composition comprising and agent that promote remyelination and detecting after the first dose one or more characteristics of peripheral nerve recovery, the presence of one or more characteristics of peripheral nerve recovery indicating a peripheral nerve injury has a capacity for recovery and the absence of characteristics of peripheral nerve recovery indicating a peripheral nerve injury without a capacity for recovery.
FILED Tuesday, November 26, 2019
APPL NO 16/696095
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0024 (20130101)
A61K 9/1647 (20130101) Original (OR) Class
A61K 9/7007 (20130101)
A61K 31/4409 (20130101)
A61K 45/06 (20130101)
A61K 47/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654123 Barnett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) West Virginia University (Morgantown, West Virginia);  University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  Temple University Of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) West Virginia University (Morgantown, West Virginia);  University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  Temple University Of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) John B. Barnett (Morgantown, West Virginia);  Harry C. Blair (Pittsburgh, Pennsylvania);  Jonathan Soboloff (Cheltenham, Pennsylvania)
ABSTRACT This invention provides a composition comprising Formula I, or salt thereof,
wherein X is chlorine, Y is a methyl group, and R is an alkyl group having a carbon chain length of three carbon atoms. A method of inhibiting osteoclast development and a method for preventing bone erosion in a patient using the compositions of Formula I are disclosed.
FILED Wednesday, May 20, 2020
APPL NO 16/879484
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/167 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654137 Oyelere et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Adegboyega K. Oyelere (Marietta, Georgia);  Verjine Khodaverdian (Atlanta, Georgia);  Subhasish Tapadar (Atlanta, Georgia)
ABSTRACT Compositions and methods for inhibiting histone lysine demethylases are provided. Several new DFP-based KDM inhibitors which alter the velocity of HP1-mediated heterochromatin gene repression are provided.
FILED Wednesday, March 20, 2019
APPL NO 16/982559
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4439 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 401/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654147 Yu et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  The United States of America, as Represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Paul B. Yu (Boston, Massachusetts);  Wenwei Huang (Rockville, Maryland);  Philip Edward Sanderson (Bethesda, Maryland);  Jian-Kang Jiang (Columbia, Maryland);  Khalida Shamim (Gaithersburg, Maryland);  Wei Zheng (Potomac, Maryland);  Xiuli Huang (Potomac, Maryland);  Gregory Tawa (Doylestown, Pennsylvania);  Arthur Lee (San Jose, California);  Asaf Alimardanov (North Bethesda, Maryland);  Junfeng Huang (Woodstock, Maryland)
ABSTRACT The present invention provides small-molecule inhibitors of BMP signaling and compositions and methods for inhibiting BMP signaling. These compounds and compositions may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds and compositions may also be used to treat subjects with Sjögren's syndrome, or diffuse intrinsic pontine glioma (DIPG).
FILED Monday, June 07, 2021
APPL NO 17/340589
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101) Original (OR) Class
A61K 31/551 (20130101)
A61K 31/675 (20130101)
A61K 31/5377 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/08 (20180101)

Heterocyclic Compounds
C07D 487/04 (20130101)
C07D 519/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/6561 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654148 Strum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) G1 Therapeutics, Inc. (Research Triangle Park, North Carolina)
ASSIGNEE(S) G1 Therapeutics, Inc. (Research Triangle Park, North Carolina)
INVENTOR(S) Jay Copeland Strum (Hillsborough, North Carolina);  John Emerson Bisi (Chapel Hill, North Carolina);  Patrick Joseph Roberts (Durham, North Carolina);  Francis X. Tavares (Durham, North Carolina)
ABSTRACT This invention is in the area of improved compounds for and methods of treating selected RB-positive cancers and other Rb-positive abnormal cellular proliferative disorders while minimizing the deleterious effects on healthy cells, for example healthy Hematopoietic Stem Cells and Progenitor Cells (HSPCs), associated with current treatment modalities. In one aspect, improved treatment of select RB-positive cancers is disclosed using specific compounds disclosed herein. In certain embodiments, the compounds described herein act as highly selective and, in certain embodiments, short, transiently-acting cyclin-dependent kinase 4/6 (CDK 4/6) inhibitors when administered to subjects.
FILED Monday, February 22, 2021
APPL NO 17/181638
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 31/519 (20130101)
A61K 31/527 (20130101) Original (OR) Class
A61K 31/555 (20130101)
A61K 31/5377 (20130101)
A61K 31/7048 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 35/04 (20180101)

Heterocyclic Compounds
C07D 487/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654149 Zon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S) Leonard I. Zon (Wellesley, Massachusetts);  Alison M. Taylor (Cambridge, Massachusetts)
ABSTRACT The present invention relates generally to methods, compositions and kits for treatment of ribosomal disorders and ribosomopathy, e.g. Diamond Blackfan anemia (DBA). In some embodiments, the invention relates to methods for the use of calmodulin inhibitors and calcium channel blockers for treatment of ribosomal disorders and ribosomopathy, e.g. Diamond Blackfan anemia (DBA).
FILED Monday, June 21, 2021
APPL NO 17/353717
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/54 (20130101)
A61K 31/145 (20130101)
A61K 31/495 (20130101)
A61K 31/553 (20130101) Original (OR) Class
A61K 31/4184 (20130101)
A61K 31/4375 (20130101)
A61K 31/4418 (20130101)
A61K 31/4965 (20130101)
A61K 31/5415 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654157 Grindrod et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Shuttle Pharmaceuticals, Inc. (Rockville, Maryland)
ASSIGNEE(S) Shuttle Pharmaceuticals, Inc. (Rockville, Maryland)
INVENTOR(S) Scott Grindrod (Rockville, Maryland);  Mira Jung (Rockville, Maryland);  Olga Timofeeva (Rockville, Maryland);  Milton Brown (Rockville, Maryland);  Anatoly Dritschilo (Rockville, Maryland)
ABSTRACT Methods and formulations are provided for treating cancer and neoplastic diseases in conjunction with radiation therapy where such methods and formulations include a combination of a radiosensitizing agent that is metabolized by thymidine phosphorylase and a thymidine phosphorylase inhibitor that increases the half-life of the radiosensitizing agent.
FILED Tuesday, January 09, 2018
APPL NO 16/475999
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/513 (20130101)
A61K 31/7072 (20130101) Original (OR) Class
A61K 33/243 (20190101)
A61K 2121/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654161 Hartung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Thomas Hartung (Baltimore, Maryland);  David Pamies (Baltimore, Maryland);  Helena T. Hogberg (Nottingham, Maryland)
ABSTRACT The present invention relates to novel compositions and methods to produce 3D organ equivalents of the brain (i.e. “mini-brains”). The invention also relates to methods of using human induced pluripotent stem cells, a combination of growth and other soluble factors and gyratory shaking. Cells from healthy or diseased donors or animals can be used to allow testing different genetic backgrounds. The model can be further enhanced by using genetically modified cells, adding micro-glia or their precursors or indicator cells (e.g. with reporter genes or tracers) as well as adding endothelial cells to form a blood-brain-barrier.
FILED Monday, December 02, 2019
APPL NO 16/700750
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/30 (20130101) Original (OR) Class
A61K 38/41 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0062 (20130101)
C12N 5/0696 (20130101)
C12N 2501/11 (20130101)
C12N 2501/13 (20130101)
C12N 2501/22 (20130101)
C12N 2501/115 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
G01N 33/58 (20130101)
G01N 33/6893 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654178 Watnick
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
INVENTOR(S) Randolph S. Watnick (Newton, Massachusetts)
ABSTRACT Provided herein are cyclic prosaposin peptides and compositions and uses thereof. Exemplary uses include use in the treatment of cancer or in the treatment of inflammatory diseases or disorders.
FILED Wednesday, November 03, 2021
APPL NO 17/518074
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/08 (20130101)
A61K 38/12 (20130101) Original (OR) Class

Peptides
C07K 7/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654179 Kumar-Singh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) Rajendra Kumar-Singh (Weston, Massachusetts);  Derek Leaderer (Boston, Massachusetts);  Siobhan M. Cashman (Boston, Massachusetts)
ABSTRACT Compositions, methods and kits are provided for treating complement related disorders in a subject with protein in combination having protein fusions of at least two of a CD46 protein, a CD55 protein and a CD59 protein or with a recombinant chimeric protein having at least two of a CD46 protein, a CD55 protein and a CD59 protein or with nucleic acids encoding these proteins. The composition negatively modulates classical and alternative complement pathways thereby treating complement related disorder such as macular degeneration, age-related macular degeneration, diabetic retinopathy, inflammatory bowel disease, thyroiditis, cryoglobulinaemia, fetal loss, organ graft rejection, cancer, etc.
FILED Friday, October 09, 2020
APPL NO 17/067515
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Sanitary Equipment Not Otherwise Provided for; Toilet Accessories
A47K 7/026 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/177 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/00 (20180101)

Cleaning in General; Prevention of Fouling in General
B08B 7/02 (20130101)

Handles for Hand Implements
B25G 1/04 (20130101)
B25G 1/06 (20130101)

Peptides
C07K 14/70596 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
G01N 2333/4716 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654181 Williams
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Wake Forest University Health Sciences (Winston-Salem, North Carolina)
ASSIGNEE(S) Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S) James K. Williams (Clemmons, North Carolina)
ABSTRACT This invention relates to C-X-C motif chemokine 12 (CXCL12), also known as stromal cell-derived factor 1 (SDF-1), vectors encoding the same, and methods of using the same for a male subject that has undergone prostate surgery to treat urological symptoms of the surgery.
FILED Friday, August 10, 2018
APPL NO 16/637498
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0031 (20130101)
A61K 9/0034 (20130101)
A61K 38/195 (20130101) Original (OR) Class
A61K 48/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 15/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654185 Raghavan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Preeti Raghavan (Brooklyn, New York);  Antonio Stecco (Padua, Italy)
ABSTRACT Provided are methods and kits for reducing the severity of muscle stiffness. The method comprises delivering to one or more specific locations in the deep fascia of an affected muscle a composition comprising a therapeutically effective amount of hyaluronidase.
FILED Monday, June 03, 2019
APPL NO 16/429272
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/47 (20130101) Original (OR) Class
A61K 47/02 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 21/02 (20180101)

Enzymes
C12Y 302/01035 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654193 Kipps et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Thomas J. Kipps (San Diego, California);  Liguang Chen (San Diego, California);  Bing Cui (San Diego, California)
ABSTRACT There are provided, inter alia, compositions and methods for treatment of cancer. The methods include administering to a subject in need a therapeutically effective amount of a Bruton's tyrosine kinase (BTK) antagonist and a ROR-1 antagonist. Further provided are pharmaceutical compositions including a BTK antagonist, ROR-1 antagonist and a pharmaceutically acceptable excipient. In embodiments, the BTK antagonist is ibrutinib and the ROR-1 antagonist is cirmtuzumab.
FILED Friday, May 08, 2020
APPL NO 16/870803
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/519 (20130101)
A61K 31/519 (20130101)
A61K 39/39558 (20130101) Original (OR) Class
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 16/2803 (20130101)
C07K 2317/24 (20130101)
C07K 2317/56 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654204 Steinmetz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Nicole Steinmetz (San Diego, California);  Michael Bruckman (Cleveland, Ohio)
ABSTRACT A rod-shaped plant virus having an interior surface and an exterior surface, and at least one imaging agent that is linked to the interior and/or exterior surface is described. The rod-shaped viruses can be combined into larger spherical nanoparticles. A rod-shaped plant virus or spherical nanoparticles including an imaging agent can be used in a method of generating an image of a tissue region of a subject such as a tumor or atherosclerotic tissue by administering the virus particle to the subject and generating an image of the tissue region of the subject to which the virus particle has been distributed.
FILED Tuesday, June 01, 2021
APPL NO 17/335557
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/1884 (20130101)
A61K 49/1896 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/00031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654286 McIntyre et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Cameron McIntyre (Lakewood, Ohio);  Amir Ali Farokhniaee (Cleveland, Ohio)
ABSTRACT Embodiments discussed herein facilitate implementation of one or more DBS pulsing strategies that maximize synaptic suppression with the minimum number of stimuli. One example embodiment comprises a non-transitory computer-readable medium storing computer-executable instructions that, when executed, cause a processor to perform operations, comprising: applying deep brain stimulation (DBS) electrical stimulation according to a first mode to cause steady-state excitatory post-synaptic current (EPSC) suppression in a set of synapses; and applying DBS electrical stimulation according to a second mode that is different than the first mode to maintain EPSC suppression in the set of synapses.
FILED Monday, June 29, 2020
APPL NO 16/914877
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0534 (20130101)
A61N 1/36139 (20130101)
A61N 1/36171 (20130101) Original (OR) Class
A61N 1/36175 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654402 Bruening et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
ASSIGNEE(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
INVENTOR(S) Merlin L. Bruening (East Lansing, Michigan);  Salinda Wijeratne (East Lansing, Michigan);  Wenjing Ning (East Lansing, Michigan);  Jinlan Dong (East Lansing, Michigan);  Weijing Liu (East Lansing, Michigan)
ABSTRACT The disclosure relates to processes, related polyacid polymers, and related articles for functionalizing a porous membrane by contacting the membrane with a polyacid polymer at low pH to stably adsorb a polyacid layer on the membrane pore surface, in particular polyacid polymers including repeating units with a pendent metal-binding ligand or star polyacid polymers. The resulting functionalized membrane is characterized by a high density of free acid groups, resulting in a higher specific capacity for its intended application. The process allows functionalization of porous membranes in a very simple, one-step process, for example without a need to derivatize an adsorbed polyacid layer to impart metal-binding ligand functionality thereto. Such functional membranes may find multiple uses, including rapid, selective binding of proteins for their purification or immobilization.
FILED Tuesday, September 15, 2020
APPL NO 17/021105
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 67/0088 (20130101)
B01D 67/0093 (20130101)
B01D 69/02 (20130101)
B01D 69/141 (20130101)
B01D 69/142 (20130101) Original (OR) Class
B01D 69/144 (20130101)
B01D 71/38 (20130101)
B01D 71/40 (20130101)
B01D 71/60 (20130101)
B01D 71/64 (20130101)
B01D 71/82 (20130101)

Compositions of Macromolecular Compounds
C08L 73/02 (20130101)
C08L 77/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654434 Lockery
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) NemaMetrix Inc. (Eugene, Oregon);  University of Oregon (Eugene, Oregon)
ASSIGNEE(S) NemaMetrix Inc. (Eugene, Oregon);  University of Oregon (Eugene, Oregon)
INVENTOR(S) Shawn Lockery (Eugene, Oregon)
ABSTRACT Disclosed herein are microinjection chips, devices, and systems for injection of unicellular or multicellular organisms. The microinjection chip and device disclosed herein include the microfluidic features, inlet port, pre-injection reservoir, injection channel and post injection channel in fluid communication with each other. The inlet port is adapted to sequentially move individual organisms into the injection channel, which is adapted to immobilize the individual organism in fluid. The injection channel features a side wall adapted to receive a microinjection pipette without a microinjection port and to reseal when the microinjection pipette is removed.
FILED Monday, June 24, 2019
APPL NO 16/449707
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0336 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502715 (20130101)
B01L 3/502753 (20130101)
B01L 3/502761 (20130101) Original (OR) Class

Apparatus for Enzymology or Microbiology;
C12M 33/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/89 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655210 Fava et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Maurizio Fava (Newton, Massachusetts);  Xudong Huang (Andover, Massachusetts)
ABSTRACT The present application relates to a compound which may be useful for mediating NO production and improving L-arginine bioavailability in a subject. Pharmaceutical compositions comprising the compound and methods of using the compound are also provided.
FILED Monday, May 20, 2019
APPL NO 17/056521
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 279/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655212 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) Jinkun Chen (Lexington, Massachusetts);  Qisheng Tu (Newton, Massachusetts);  Xingwen Wu (Boston, Massachusetts);  Gang Chen (Shanghai, China PRC);  Wei Qiu (Boston, Massachusetts)
ABSTRACT Disclosed herein are adiponectin receptor agonists and methods of using the same for the treatment of inflammation or bone loss in a subject.
FILED Tuesday, December 14, 2021
APPL NO 17/550834
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/08 (20180101)
A61P 29/00 (20180101)

Heterocyclic Compounds
C07D 211/58 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655236 Bogyo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Matthew S. Bogyo (Redwood City, California);  Martijn Verdoes (Nijmegen, Netherlands)
ABSTRACT Activity-based probe compounds for use in labeling a cysteine protease are provided. The compounds are targeted to the protease through a specific targeting element. The compounds additionally include a detectable element, such as a fluorescent label, a radiolabel, or a chelator. In some cases, the compounds additionally include a quenching element that is released upon reaction with the protease. Also provided are compositions comprising the compounds and methods for using the compounds, for example in labeling a protease in an animal and in visualizing a tumor in an animal.
FILED Monday, November 09, 2020
APPL NO 17/092587
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0032 (20130101)
A61K 49/0034 (20130101)
A61K 49/0041 (20130101)

Heterocyclic Compounds
C07D 401/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655288 Witztum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Joseph L. Witztum (San Diego, California);  Sotirios Tsimikas (San Diego, California);  Xuchu Que (San Diego, California)
ABSTRACT The disclosure provides for single chain variable fragments to oxidized phospholipid epitopes and methods of use thereof, including the production of transgenic animal models and the use of the fragments as therapeutic agents for treating CAS.
FILED Tuesday, May 29, 2018
APPL NO 15/991792
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0275 (20130101)
A01K 67/0278 (20130101)
A01K 2217/15 (20130101)
A01K 2217/052 (20130101)
A01K 2217/206 (20130101)
A01K 2227/105 (20130101)
A01K 2267/01 (20130101)
A01K 2267/0362 (20130101)
A01K 2267/0368 (20130101)
A01K 2267/0375 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/76 (20130101)
C07K 2317/622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655299 Debinski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Wake Forest University Health Sciences (Winston-Salem, North Carolina)
ASSIGNEE(S) Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S) Waldemar Debinski (Winston-Salem, North Carolina);  Denise Mazess Herpai (Winston-Salem, North Carolina)
ABSTRACT Provided herein are monoclonal antibodies that specifically bind IL-13RA2 with cross-reactivity in humans and canines. Also provided are methods of use of the antibodies in the treatment and monitoring of cancers.
FILED Tuesday, May 05, 2020
APPL NO 16/866736
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/3955 (20130101)
A61K 47/6813 (20170801)
A61K 47/6829 (20170801)
A61K 47/6849 (20170801)
A61K 47/6851 (20170801)
A61K 47/6911 (20170801)
A61K 49/0004 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/2866 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/33 (20130101)
C07K 2317/34 (20130101)
C07K 2317/56 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/93 (20130101)

Enzymes
C12Y 603/01004 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/58 (20130101)
G01N 33/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655468 Gao
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Trustees of Boston College (Chestnut Hill, Massachusetts)
ASSIGNEE(S) The Trustees of Boston College (Chesnut Hill, Morocco)
INVENTOR(S) Jianmin Gao (Newton, Massachusetts)
ABSTRACT Provided is a chemically modified phage display platform and method of use thereof. More specifically, the present disclosure provides a chemically modified phage display library that incorporates 2-acetylphenylboronic acid (APBA) moieties to elicit dynamic covalent binding to the bacterial cell surface. The APBA-modified phage display libraries described herein are applicable to a wide array of bacterial strains and/or mammalian cells, paving the way to facile diagnosis and development of strain-specific antibiotics, and/or peptide-antibiotic conjugates for effective and targeted treatment. Also provided are therapeutic peptides, and pharmaceutical compositions thereof, that are identified by screening the phage display library of the present disclosure, and method of use of such therapeutic peptides for effective and targeted treatment.
FILED Monday, January 25, 2021
APPL NO 17/156908
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/1037 (20130101) Original (OR) Class
C12N 2795/00011 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655469 Saleh et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland);  miRecule, Inc. (Rockville, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  miRenlo, Inc. (Rockville, Maryland)
INVENTOR(S) Anthony D. Saleh (Potomac, Maryland);  Carter Van Waes (Brookeville, Maryland);  Zhong Chen (Bethesda, Maryland);  Hui Cheng (Falls Church, Virginia)
ABSTRACT Disclosed herein are methods of treating a tumor in a subject, including administering to the subject one or more miRNA nucleic acids or variants (such as mimics or mimetics) thereof with altered expression in the tumor. Also disclosed herein are compositions including one or more miRNA nucleic acids. In some examples, the miRNA nucleic acids are modified miRNAs, for example, and miRNA nucleic acid including one or more modified nucleotides and/or a 5′-end and/or 3′-end modification. In particular examples, the modified miRNA nucleic acid is an miR-30a nucleic acid. Further disclosed herein are methods of diagnosing a subject as having a tumor with altered expression of one or more miRNA nucleic acids. In some embodiments, the methods include detecting expression of one or more miRNAs in a sample from the subject and comparing the expression in the sample from the subject to a control.
FILED Tuesday, March 07, 2017
APPL NO 16/082852
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 45/06 (20130101)
A61K 47/6849 (20170801)
A61K 47/6913 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/141 (20130101)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/322 (20130101)
C12N 2310/346 (20130101)
C12N 2310/3521 (20130101)
C12N 2310/3533 (20130101)
C12N 2320/32 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655470 Bonnemann et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland);  MURDOCH UNIVERSITY (Perth, Australia);  THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts);  UCL BUSINESS PLC (London, United Kingdom)
ASSIGNEE(S) The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Carsten G. Bonnemann (Washington, District of Columbia);  Veronique Bolduc (Rockville, Maryland);  Francesco Muntoni (London, United Kingdom);  Steve Wilton (Applecross, Australia);  Daniel Macarthur (Cambridge, Massachusetts);  Monkol Lek (Braintree, Massachusetts);  Beryl Cummings (Brookline, Massachusetts)
ABSTRACT A single nucleotide polymorphism (SNP) that results in development of a Type VI collagen, alpha 1 chain-related disorder, and the use of the SNP to identify individuals at risk for developing COL6-related disorders (COL6-RD). Also provided are antisense oligomers for treating individuals at risk for developing COL6-RD, as well as methods for screening compounds for their potential as therapeutic agents.
FILED Wednesday, July 05, 2017
APPL NO 16/315278
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/3233 (20130101)
C12N 2320/33 (20130101)
C12N 2800/60 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655483 Gao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Child Health and Human Development (NICHD)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Guangping Gao (Westborough, Massachusetts);  Phillip Tai (Worcester, Massachusetts);  Manish Muhuri (Worcester, Massachusetts);  Wei Zhan (Worcester, Massachusetts)
ABSTRACT The disclosure, in some aspects, relates to nucleic acids, compositions and kits useful for gene therapy with reduced immune response to transgene products.
FILED Friday, January 21, 2022
APPL NO 17/581306
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101) Original (OR) Class
C12N 15/113 (20130101)
C12N 2310/141 (20130101)
C12N 2320/32 (20130101)
C12N 2330/51 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14171 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655506 Plaas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Rush University Medical Center (Chicago, Illinois);  The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) Rush University Medical Center (Chicago, Illinois);  The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Anna Plaas (Chicago, Illinois);  Vincent Wang (Naperville, Illinois);  John Sandy (Chicago, Illinois);  Rebecca Bell (New York, New York);  Jorge Galante (Sanibel, Florida);  Katie J. Trella (Chicago, Illinois)
ABSTRACT A method for monitoring a treatment of a subject having a musculoskeletal disorder is provided. The method includes measuring a first expression level of at least two biomarkers at a treatment site prior to the treatment and measuring a second expression level of the at least two biomarkers at the treatment site after the treatment begins. The method further includes comparing the first expression level of the at least two biomarkers prior to the treatment to the second expression level of the at least two biomarkers post treatment and continuing the treatment, altering the treatment or stopping the treatment based on the comparison. A method of treating a musculoskeletal disorder in a subject is also provided. The method includes removing a aggrecan-hyaluronan matrix from a treatment site in the subject.
FILED Wednesday, January 14, 2015
APPL NO 15/111395
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/43 (20130101)
A61K 38/1841 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6887 (20130101)
G01N 2800/10 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655508 Watnick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Athena Diagnostics, Inc. (Marlborough, Massachusetts);  The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) Athena Diagnostics, Inc. (Marlborough, Massachusetts);  The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Terry J. Watnick (Chevy Chase, Maryland);  Miguel Garcia-Gonzalez (Brion, Spain);  Gregory G. Germino (Chevy Chase, Maryland);  Jeffery G. Jones (Wilbraham, Massachusetts)
ABSTRACT The present invention relates to methods of detecting novel mutations in a PKD1 and/or PKD2 gene that have been determined to be associated with autosomal dominant polycystic kidney disease (ADPKD) in order to detect or predict the occurrence of ADPKD in an individual.
FILED Monday, August 31, 2020
APPL NO 17/008385
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656164 Simpson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Garth Jason Simpson (West Lafayette, Indiana);  Chen Li (West Lafayette, Indiana);  Changqin Ding (West Lafayette, Indiana)
ABSTRACT A method of obtaining a measurement signal representative of the particle size distributions in nanocrystal suspensions that includes a step of providing a first light beam along a first axis to a first micro-retarder array to generate polarization wavefront shaped light. The shaped light is applied to an objective configured to focus two orthogonally polarized components of the polarization wavefront shaped light to produce first and second axially offset foci along the first axis. A sample having particles in suspension is disposed in one foci to produce a measurement optical signal having phase and intensity values corresponding to at least some of the particles in suspension. The method also includes determining intensity and quantitative phase information as a function of time based on the optical signals.
FILED Monday, May 24, 2021
APPL NO 17/329017
ART UNIT 2877 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/0224 (20130101)
G01J 3/457 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/0211 (20130101) Original (OR) Class
G01N 15/0227 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656221 Avery et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Adam William Avery (Rochester Hills, Michigan);  Thomas S. Hays (St. Paul, Minnesota);  David D. Thomas (Minneapolis, Minnesota);  Michael E. Fealey (Dallas, Texas);  Robyn T. Rebbeck (Minneapolis, Minnesota)
ABSTRACT The present disclosure provides methods for identifying compounds that cause structural changes in a protein bound to an actin filament. The methods include the use of cells that include two actin-binding proteins, each labeled with a chromophore, and exposing the cells to a test compound. The method further includes detecting a change in fluorescence resonance energy transfer (FRET) between the chromophores.
FILED Wednesday, June 10, 2020
APPL NO 16/897977
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 33/502 (20130101) Original (OR) Class
G01N 2021/6439 (20130101)
G01N 2333/4712 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656233 Bertozzi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trastees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Carolyn Bertozzi (Menlo Park, California);  Stephen J. Galli (Portola Valley, California);  Kaori Mukai (Cambridge, Massachusetts);  Peter Robinson (San Francisco, California);  Cheng-ting Tsai (Palo Alto, California);  Mindy Tsai (Palo Alto, California)
ABSTRACT Methods and reagents for multiplex detection of antibodies are disclosed. In particular, the invention relates to multiplex detection of antibodies using antigen-DNA and antibody-binding agent-DNA conjugates carrying DNA barcodes for identifying and quantitating disease-relevant antibody isotypes, such as those involved in allergic responses, autoimmune diseases, infections, and inflammation.
FILED Thursday, March 29, 2018
APPL NO 16/497668
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6806 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/564 (20130101)
G01N 33/686 (20130101) Original (OR) Class
G01N 2458/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656302 Rispoli et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Joseph Vincent Rispoli (West Lafayette, Indiana);  Jana M. Vincent (West Lafayette, Indiana)
ABSTRACT An apparatus for detecting RF signals in magnetic resonance testing procedure includes a multidirectional stretchable fabric and a flexible radio frequency (RF) coil. The flexible RF coil has a coil shape, and comprises conductive fiber stitched into the stretchable fabric in a plurality of repeating, non-linear stitch patterns. The plurality of stitch patterns collectively define the coil shape.
FILED Tuesday, May 12, 2020
APPL NO 17/610929
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/34 (20130101) Original (OR) Class
G01R 33/385 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656448 Valdes et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Pablo A. Valdes (Hanover, New Hampshire);  David W. Roberts (Lyme, New Hampshire);  Keith D. Paulsen (Hanover, New Hampshire);  Frederic Leblond (Montreal, Canada)
ABSTRACT An imaging system includes an illumination device for illuminating a target. A surgical microscope receives light from the target, the surgical microscope comprising at least one optical output port at which at least a portion of the received light is provided as an output from the surgical microscope. A tunable filter receives the portion of the received light provided as the output from the surgical microscope, the tunable filter being tunable to pass a filtered portion of the received light, the filtered portion of the received light having a plurality of wavelengths selected by the tunable filter and provided as output from the tunable filter. A high-resolution, broad-bandwidth electronic camera receives the light of a plurality of wavelengths selected by the tunable filter, the electronic camera converting the light of a plurality of wavelengths selected by the tunable filter to a plurality of electrical signals. A processor processes the plurality of electrical signals to form an image of the target.
FILED Monday, June 17, 2019
APPL NO 16/443760
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/063 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101) Original (OR) Class
G02B 21/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657311 Kovacs
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Istvan Kovacs (Brighton, Massachusetts)
ABSTRACT A method and corresponding system identify missing interactions in incompletely known datasets represented as complex networks. The method identifies missing connections in a complex network. The method accesses an electronic representation of the network. The network includes nodes and links, the nodes represent entities, and the links represent interactions between the entities. For each pair of nodes not directly connected by a link, the method determines a number of paths connecting the pair of nodes and calculates a prediction score for the pair of nodes based on the number of paths connecting the pair of nodes. The method ranks the pairs of nodes based on the prediction scores, resulting in an ordered list of node pairs, and selects at least a subset of the pairs of nodes based on the ordered list of node pairs. The selected pairs of nodes represent missing connections in the network.
FILED Monday, May 21, 2018
APPL NO 15/985023
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/022 (20130101)
G06N 7/01 (20230101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 30/0631 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 5/20 (20190201)
G16B 20/00 (20190201)
G16B 30/00 (20190201)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/10 (20180101)
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657486 Buckler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) ELUCID BIOIMAGING INC. (Boston, Massachusetts)
ASSIGNEE(S) ELUCID BIOIMAGING INC. (Boston, Massachusetts)
INVENTOR(S) Andrew J. Buckler (Boston, Massachusetts);  Changguo Ji (Lexington, Massachusetts);  Murali Ayyapillai (Acton, Massachusetts)
ABSTRACT Systems and methods for improving soft tissue contrast, characterizing tissue, classifying phenotype, stratifying risk, and performing multi-scale modeling aided by multiple energy or contrast excitation and evaluation are provided. The systems and methods can include single and multi-phase acquisitions and broad and local spectrum imaging to assess atherosclerotic plaque tissues in the vessel wall and perivascular space.
FILED Wednesday, July 27, 2022
APPL NO 17/874617
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/463 (20130101)
A61B 6/482 (20130101)
A61B 6/504 (20130101)
A61B 6/4241 (20130101)
A61B 6/5247 (20130101)

Image Data Processing or Generation, in General
G06T 5/50 (20130101) Original (OR) Class
G06T 7/0012 (20130101)
G06T 7/174 (20170101)
G06T 2207/10081 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/10132 (20130101)
G06T 2207/20216 (20130101)
G06T 2207/20224 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657895 Baliga et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) INSTITUTE FOR SYSTEMS BIOLOGY (Seattle, Washington)
ASSIGNEE(S) INSTITUTE FOR SYSTEMS BIOLOGY (Seattle, Washington)
INVENTOR(S) Nitin S. Baliga (Tempe, Arizona);  Christopher L. Plaisier (Tempe, Arizona)
ABSTRACT The invention includes methods and systems for identifying targets for therapeutic intervention for various diseases and conditions; and provides specific materials and methods for treatment of specific diseases and conditions.
FILED Wednesday, May 03, 2017
APPL NO 16/097897
ART UNIT 1672 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 2310/141 (20130101)
C12N 2320/11 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 15/30 (20190201) Original (OR) Class
G16B 25/10 (20190201)
G16B 40/00 (20190201)
G16B 45/00 (20190201)
G16B 50/00 (20190201)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/50 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657918 Rasmussen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Luke V. Rasmussen (Wilmette, Illinois);  Justin B. Starren (Wilmette, Illinois);  Carl Christensen (Terra Ceia, Florida);  Federico A. Almaraz (Chicago, Illinois);  Maureen E. Smith (Chicago, Illinois)
ABSTRACT Systems and methods for integrating genomic results with electronic health records in accordance with embodiments of the invention are disclosed. In one embodiment, a method includes obtaining first raw genetic data formatted in a first format, obtaining second raw genetic data formatted in a second format normalizing the first raw genetic data by substituting at least one symbol in the first raw genetic data, normalizing the second raw genetic data, generating genetic data for the patient by modifying the first raw genetic data by converting the normalized symbols in the first raw genetic data to a common format, modifying the second raw genetic data by converting the normalized symbols in the second raw genetic data to the common format, and generating the genetic data for the patient based on the first raw genetic data and the second raw genetic data, and storing the genetic data.
FILED Tuesday, June 18, 2019
APPL NO 16/444742
ART UNIT 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Electric Digital Data Processing
G06F 16/258 (20190101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 50/00 (20190201)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/10 (20180101)
G16H 50/20 (20180101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658638 Green et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Scott R. Green (Maumee, Ohio);  Yogesh Gianchandani (Ann Arbor, Michigan);  Ramprasad M. Nambisan (Ann Arbor, Michigan);  Jiqing Jiang (Mountain View, California)
ABSTRACT A resonator comprising a magnetoelastic body having a mass load portion and an active resonating portion can be used in implementations such as a security tag. The resonator includes a mass at the mass load portion of the magnetoelastic body. Displacement of the magnetoelastic body is configured to occur at both the mass load portion and the active resonating portion. A strain at the active resonating portion during displacement is configured to be greater than a strain at the mass load portion during displacement.
FILED Friday, August 28, 2020
APPL NO 17/006014
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Impedance Networks, e.g Resonant Circuits; Resonators
H03H 3/06 (20130101)
H03H 9/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11654034 Langenfeld et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S) DEKA Products Limited Partnership (Manchester, New Hampshire)
ASSIGNEE(S) DEKA PRODUCTS LIMITED PARTNERSHIP (Manchester, New Hampshire)
INVENTOR(S) Christopher C. Langenfeld (Nashua, New Hampshire);  Christopher O. Evans (Amherst, New Hampshire);  Stanley B. Smith, III (Raymond, New Hampshire);  Alexander H. Muller (Manchester, New Hampshire);  John M. Kerwin (Manchester, New Hampshire);  Thomas S. Schnellinger (North Andover, Massachusetts);  G. Michael Guay (Greenville, New Hampshire);  Dirk A. van der Merwe (Manchester, New Hampshire)
ABSTRACT A prosthetic arm apparatus comprising a plurality of segments that provide a user of the prosthetic arm apparatus with substantially the same movement capability and function as a human arm. The segments are connectable to one another and connectable to a harness mount that may be adorned by the user. Each segment of the plurality of segments provides a portion of the movement capability, enabling the plurality of connected segments connected to the harness mount to provide substantially the same movement capability as that lacking in the user.
FILED Friday, May 24, 2019
APPL NO 16/421558
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/54 (20130101) Original (OR) Class
A61F 2/70 (20130101)
A61F 2/78 (20130101)
A61F 2/581 (20130101)
A61F 2/582 (20130101)
A61F 2/583 (20130101)
A61F 2/585 (20130101)
A61F 2/586 (20130101)
A61F 2002/507 (20130101)
A61F 2002/543 (20130101)
A61F 2002/546 (20130101)
A61F 2002/587 (20130101)
A61F 2002/701 (20130101)
A61F 2002/704 (20130101)
A61F 2002/764 (20130101)
A61F 2002/5001 (20130101)
A61F 2002/5059 (20130101)
A61F 2002/5061 (20130101)
A61F 2002/5069 (20130101)
A61F 2002/5083 (20130101)
A61F 2002/6827 (20130101)
A61F 2002/6836 (20130101)
A61F 2002/6845 (20130101)
A61F 2002/6854 (20130101)
A61F 2002/6863 (20130101)
A61F 2002/7625 (20130101)
A61F 2002/7635 (20130101)
A61F 2002/7862 (20130101)
A61F 2002/30462 (20130101)
A61F 2220/0075 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654147 Yu et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  The United States of America, as Represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Paul B. Yu (Boston, Massachusetts);  Wenwei Huang (Rockville, Maryland);  Philip Edward Sanderson (Bethesda, Maryland);  Jian-Kang Jiang (Columbia, Maryland);  Khalida Shamim (Gaithersburg, Maryland);  Wei Zheng (Potomac, Maryland);  Xiuli Huang (Potomac, Maryland);  Gregory Tawa (Doylestown, Pennsylvania);  Arthur Lee (San Jose, California);  Asaf Alimardanov (North Bethesda, Maryland);  Junfeng Huang (Woodstock, Maryland)
ABSTRACT The present invention provides small-molecule inhibitors of BMP signaling and compositions and methods for inhibiting BMP signaling. These compounds and compositions may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. These compounds and compositions may also be used to treat subjects with Sjögren's syndrome, or diffuse intrinsic pontine glioma (DIPG).
FILED Monday, June 07, 2021
APPL NO 17/340589
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101) Original (OR) Class
A61K 31/551 (20130101)
A61K 31/675 (20130101)
A61K 31/5377 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/08 (20180101)

Heterocyclic Compounds
C07D 487/04 (20130101)
C07D 519/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/6561 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654225 Batchinsky et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) The Geneva Foundation (Tacoma, Washington)
ASSIGNEE(S) The Geneva Foundation (Tacoma, Washington)
INVENTOR(S) Andriy I. Batchinsky (San Antonio, Texas);  George T. Harea (San Antonio, Texas);  Daniel S. Wendorff (San Antonio, Texas);  Brendan M. Beely (San Antonio, Texas);  Teryn R. Roberts (San Antonio, Texas)
ABSTRACT In one exemplary embodiment, a wearable extracorporeal life support device includes a catheter fluidly connected to a pump and first and second modular extracorporeal life support components. The device may also be configured to be attached to a garment. The pump and the first and second modular extracorporeal life support components may be fluidly connected in series. The pump and the first and second modular extracorporeal life support components may also be fluidly connected in parallel. The first modular extracorporeal life support component may be a lung membrane and the second modular extracorporeal life support component may be a dialysis membrane.
FILED Thursday, June 27, 2019
APPL NO 16/454486
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/6866 (20130101)
A61B 5/6867 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/16 (20130101)
A61M 1/34 (20130101)
A61M 1/1698 (20130101)
A61M 1/3659 (20140204)
A61M 1/3667 (20140204) Original (OR) Class
A61M 60/31 (20210101)
A61M 60/37 (20210101)
A61M 60/38 (20210101)
A61M 60/113 (20210101)
A61M 60/216 (20210101)
A61M 60/232 (20210101)
A61M 60/279 (20210101)
A61M 60/546 (20210101)
A61M 2209/088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654332 Eder
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) INCLUDEHEALTH, INC. (Mason, Ohio)
ASSIGNEE(S) IncludeHealth, Inc. (Cincinnati, Ohio)
INVENTOR(S) James Ryan Eder (Columbus, Ohio)
ABSTRACT Systems and methods for providing a customized exercise protocol to a computing device of a user. As the user performs the exercise protocol, one or more cameras of the computing device can track the user's movements. The user's movement are assessed to determine if proper form and technique is being used.
FILED Wednesday, July 14, 2021
APPL NO 17/375518
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 24/0006 (20130101)
A63B 24/0062 (20130101) Original (OR) Class
A63B 24/0075 (20130101)
A63B 2024/0068 (20130101)
A63B 2024/0071 (20130101)
A63B 2220/05 (20130101)
A63B 2220/806 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654399 Coon et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David James Coon (Cambridge, Massachusetts);  Tiama Hamkins-Indik (Cambridge, Massachusetts);  Donald E. Ingber (Boston, Massachusetts);  Miles Ingram (Cambridge, Massachusetts);  Daniel Levner (Brookline, Massachusetts);  Richard Novak (Jamaica Plain, Massachusetts);  Jefferson Puerta (Malden, Massachusetts);  Daniel E. Shea (Mendon, Massachusetts);  Josiah Sliz (Boston, Massachusetts);  Norman Wen (Newton, Massachusetts)
ABSTRACT A method for micro-molding a polymeric membrane and including pouring a predetermined volume of curable polymer unto a micro-fabricated mold having a post array with pillars, and overlaying the polymer with a support substrate. A spacer, such as a rubber spacer, is placed in contact with the support substrate and a force is applied to an exposed side of the spacer to compress the support substrate and the polymer together. While applying the force, the polymer is cured on the mold for a predetermined time period and at a predetermined temperature to form a polymeric membrane having a pore array with a plurality of pores corresponding to the plurality of pillars of the post array. The polymeric membrane is removed from the support substrate.
FILED Wednesday, March 16, 2016
APPL NO 15/558191
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Separation
B01D 67/0034 (20130101) Original (OR) Class
B01D 71/70 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502707 (20130101)
B01L 2300/123 (20130101)
B01L 2400/086 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 33/68 (20130101)
B29C 33/424 (20130101)
B29C 39/006 (20130101)
B29C 39/26 (20130101)
B29C 41/12 (20130101)
B29C 41/36 (20130101)
B29C 41/38 (20130101)
B29C 2043/025 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/755 (20130101)
B29L 2031/756 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 25/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654415 McGill et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) R. Andrew McGill (Lorton, Virginia);  Courtney A. Roberts (Washington, District of Columbia)
ABSTRACT The invention relates to strong hydrogen-bond acidic sorbents. The sorbents may be provided in a form that limits or eliminates intramolecular bonding of the hydrogen-bond acidic site between neighboring sorbent molecules, for example, by providing steric groups adjacent to the hydrogen-bond acidic site. The hydrogen bond site may be a phenolic structure based on a bisphenol architecture. The sorbents of the invention may be used in methods for trapping or detecting hazardous chemicals or explosives.
FILED Thursday, April 21, 2022
APPL NO 17/725794
ART UNIT 1796 — Optics
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/22 (20130101) Original (OR) Class
B01J 20/281 (20130101)
B01J 20/282 (20130101)
B01J 20/3425 (20130101)
B01J 20/3483 (20130101)
B01J 20/28023 (20130101)
B01J 2220/54 (20130101)

Acyclic or Carbocyclic Compounds
C07C 39/367 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 14/06 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 59/00 (20130101)
C08G 64/00 (20130101)
C08G 64/10 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/482 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654569 Blankespoor et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) BOSTON DYNAMICS, INC. (Waltham, Massachusetts)
INVENTOR(S) Kevin Blankespoor (Arlington, Massachusetts);  Benjamin Stephens (Somerville, Massachusetts);  Marco da Silva (Arlington, Massachusetts)
ABSTRACT An example method may include i) detecting a disturbance to a gait of a robot, where the gait includes a swing state and a step down state, the swing state including a target swing trajectory for a foot of the robot, and where the target swing trajectory includes a beginning and an end; and ii) based on the detected disturbance, causing the foot of the robot to enter the step down state before the foot reaches the end of the target swing trajectory.
FILED Tuesday, December 22, 2020
APPL NO 17/129996
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/16 (20130101)
B25J 9/1628 (20130101)
B25J 9/1679 (20130101)
B25J 9/1692 (20130101) Original (OR) Class

Motor Vehicles; Trailers
B62D 57/032 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
Y10S 901/46 (20130101)
Y10S 901/49 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654613 Nino et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Quest Integrated, LLC (Kent, Washington)
ASSIGNEE(S) Quest Integrated, LLC (Kent, Washington)
INVENTOR(S) Giovanni Nino (Issaquah, Washington);  Tyler Blumenthal (Renton, Washington)
ABSTRACT Systems and methods for printed multifunctional skin are disclosed herein. In one embodiment, a method of manufacturing a smart device includes providing a structure, placing a sensor over an outer surface of the structure, and placing conductive traces over the outer surface of the structure. The conductive traces electrically connect the sensor to electronics.
FILED Monday, April 05, 2021
APPL NO 17/222746
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/112 (20170801) Original (OR) Class
B29C 70/882 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/34 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Aeroplanes; Helicopters
B64C 3/26 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 45/00 (20130101)
B64D 2045/0085 (20130101)

Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 1/46 (20130101)

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 1/14 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/2206 (20130101)
G01L 1/2287 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 5/0016 (20130101)
G01M 5/0083 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654984 Blankespoor et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
INVENTOR(S) Kevin Blankespoor (Arlington, Massachusetts);  Alex Perkins (Arlington, Massachusetts);  Marco da Silva (Arlington, Massachusetts)
ABSTRACT An example method may include i) determining a first distance between a pair of feet of a robot at a first time, where the pair of feet is in contact with a ground surface; ii) determining a second distance between the pair of feet of the robot at a second time, where the pair of feet remains in contact with the ground surface from the first time to the second time; iii) comparing a difference between the determined first and second distances to a threshold difference; iv) determining that the difference between determined first and second distances exceeds the threshold difference; and v) based on the determination that the difference between the determined first and second distances exceeds the threshold difference, causing the robot to react.
FILED Tuesday, January 26, 2021
APPL NO 17/158471
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1633 (20130101)
B25J 9/1653 (20130101)
B25J 9/1694 (20130101)
B25J 13/08 (20130101)
B25J 13/085 (20130101)

Motor Vehicles; Trailers
B62D 57/02 (20130101) Original (OR) Class
B62D 57/032 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/021 (20130101)
G05D 1/027 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655197 Epshteyn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Albert Epshteyn (Potomac, Maryland);  Andrew P. Purdy (Alexandria, Virginia)
ABSTRACT A nanoparticle of a decomposition product of a transition metal aluminum hydride compound, a transition metal borohydride compound, or a transition metal gallium hydride compound. A process of: reacting a transition metal salt with an aluminum hydride compound, a borohydride compound, or a gallium hydride compound to produce one or more of the nanoparticles. The reaction occurs in solution while being sonicated at a temperature at which the metal hydride compound decomposes. A process of: reacting a nanoparticle with a compound containing at least two hydroxyl groups to form a coating having multi-dentate metal-alkoxides.
FILED Thursday, December 03, 2020
APPL NO 17/110580
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/054 (20220101)
B22F 1/102 (20220101)
B22F 9/24 (20130101)
B22F 9/24 (20130101)
B22F 9/24 (20130101)
B22F 2003/248 (20130101)
B22F 2202/01 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101) Original (OR) Class
B82Y 40/00 (20130101)

Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 45/32 (20130101)
C06B 45/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655393 Kidwell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David A. Kidwell (Alexandria, Virginia);  Thomas O'Shaughnessy (Arlington, Virginia)
ABSTRACT A mixed acrylate-siloxane polymer can be used to create three-dimensional (3D) structures of arbitrary shape via nanolithography. Treatment of such structures with amine (such as diamine) makes them permissive for neuronal cell adhesion and growth without need of additional modification such as poly-lysine (D or L) nor laminin.
FILED Monday, August 15, 2022
APPL NO 17/888009
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 17/32 (20130101)
C03C 2218/32 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 133/08 (20130101)
C09D 183/04 (20130101) Original (OR) Class

Apparatus for Enzymology or Microbiology;
C12M 25/14 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/70058 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655477 Loria et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Rosemary Loria (Gainesville, Florida);  Yucheng Zhang (Gainesville, Florida);  Yousong Ding (Gainesville, Florida);  Guangde Jiang (Gainesville, Florida)
ABSTRACT The present disclosure includes genetically engineered, non-pathogenic Streptomyces bacterium with exogenous, non-native Thaxtomin A (ThxA) biosynthetic gene clusters conferring the genetically engineered, non-pathogenic Streptomyces bacterium with the ability to produce thaxtomin A. Also included are methods of providing thaxtomin producing capability in non-native Streptomyces bacterial strains, methods of producing thaxtomin compounds with the genetically engineered Streptomyces bacteria of the present disclosure, and methods of producing thaxtomin compounds and nitro-tryptophan analogs, and fluorinated thaxtomin compounds, analogs, and intermediates with the genetically engineered Streptomyces bacteria of the present disclosure.
FILED Wednesday, May 23, 2018
APPL NO 16/616059
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/28 (20200101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)
C12N 15/76 (20130101) Original (OR) Class
C12N 2510/02 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 17/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655498 Ricke et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Darrell Orlyn Ricke (Winchester, Massachusetts);  James Harper (Jamaica Plain, Massachusetts);  Brian S. Helfer (Brookline, Massachusetts);  Joseph Isaacson (Latham, New York);  Adam M. Michaleas (Hudson, New Hampshire);  Martha S. Petrovick (Barre, Massachusetts);  Eric Schwoebel (Woburn, Massachusetts);  Anna Shcherbina (East Palo Alto, California);  Philip Fremont-Smith (Medford, Massachusetts);  James G. Watkins (Sutton, Massachusetts);  Edward C. Wack (Waltham, Massachusetts)
ABSTRACT The disclosure provides various systems and methods for identifying individuals from one or more samples. In particular, improved systems and methods of analysis are provided for handling multiple contributors, as well as systems and methods that model not only individual error rates per locus but factor in amplification of errors induced through PCR cycles. In some embodiments, modeling of error rates can be applied in multi-contributor settings to more accurately establish real alleles from artifacts. Other aspects involve application of sequencing in error modeling. Further, methods are provided for determining the presence of common individual DNA profiles in one or more complex DNA mixtures and for deconvolution of multiple complex DNA mixtures into shared individual components.
FILED Friday, July 06, 2018
APPL NO 16/629081
ART UNIT 2166 — Data Bases & File Management
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6858 (20130101) Original (OR) Class
C12Q 1/6869 (20130101)
C12Q 1/6886 (20130101)
C12Q 2600/156 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
G16B 40/10 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655715 Hayes
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Test Center (AFTC)
APPLICANT(S) Special Aerospace Services, LLC (Boulder, Colorado)
ASSIGNEE(S) Special Aerospace Services, LLC (Boulder, Colorado)
INVENTOR(S) Christopher Hayes (Denver, Colorado)
ABSTRACT Methods and systems for manipulating surface topology of additively manufactured fluid interacting structures, such as additively manufactured heat exchangers or airfoils, and associated additively manufactured articles, are disclosed. In one aspect, an article which interacts with a fluid is imparted with surface topology features which affect performance parameters related to the fluid flow. The topological features may be sequenced, combined, intermixed, and functionally varied in size and form to locally manipulate and co-optimize multiple performance parameters at each or selectable differential lengths along a flow path. The co-optimization method may uniquely prioritize selectable performance parameters at different points along the flow path to improve or enhance overall system performance. Topological features may include design features such as dimples, fins, boundary layer disruptors, and biomimicry surface textures, and manufacturing artefacts such as surface roughness and subsurface porosity distribution and morphology.
FILED Tuesday, December 22, 2020
APPL NO 17/130916
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 33/38 (20130101)
B29C 45/2612 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/14 (20130101) Original (OR) Class

Jet-propulsion Plants
F02K 9/60 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2230/31 (20130101)
F05D 2300/514 (20130101)
F05D 2300/516 (20130101)

Electric Digital Data Processing
G06F 30/15 (20200101)
G06F 30/28 (20200101)
G06F 2113/10 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656140 Miller
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Gary A. Miller (Springfield, Virginia)
ABSTRACT An active apparatus includes a pressure sensor array. The pressure sensor array includes at least one transducer and a standard optical fiber mechanically coupled thereto. The active apparatus includes a distributed Bragg reflector fiber laser located within the optical fiber. The fiber laser emits a wavelength. The fiber laser consists of two fiber Bragg gratings, which define a linear cavity. The linear cavity is mechanically coupled to the at least one transducer. A pressure change detected by the at least one transducer causes at least one property change in the optical fiber. For example, the at least one property change in the optical fiber causes a change in the cavity length. The change in the cavity length causes a wavelength shift relative to the wavelength emitted by the fiber laser.
FILED Monday, April 25, 2022
APPL NO 17/728036
ART UNIT 2878 — Optics
CURRENT CPC
Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 5/35316 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 11/04 (20130101)
G01L 11/025 (20130101) Original (OR) Class

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/186 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656192 Gupta et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Chaitanya Gupta (San Carlos, California);  Ross M. Walker (Salt Lake City, Utah);  Boris Murmann (Stanford, California);  Roger T. Howe (Stanford, California)
ABSTRACT A high-gain and low-noise negative feedback control (“feedback control”) system can detect charge transfer in quantum systems at room temperatures. The feedback control system can attenuate dissipative coupling between a quantum system and its thermodynamic environment. The feedback control system can be integrated with standard commercial voltage-impedance measurement system, for example, a potentiostat. In one aspect, the feedback control system includes a plurality of electrodes that are configured to electrically couple to a sample, and a feedback mechanism coupled to a first electrode of the plurality of electrodes. The feedback mechanism is configured to detect a potential associated with the sample via the first electrode. The feedback mechanism provides a feedback signal to the sample via a second electrode of the plurality of electrodes, the feedback signal is configured to provide excitation control of the sample at a third electrode of the plurality of electrode.
FILED Tuesday, May 11, 2021
APPL NO 17/317422
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/028 (20130101) Original (OR) Class
G01N 27/49 (20130101)
G01N 27/416 (20130101)
G01N 27/3273 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656193 Stein et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Analog Devices International Unlimited Company (Limerick, Ireland);  Analog Devices, Inc. (Wilmington, Massachusetts)
ASSIGNEE(S) Analog Devices, Inc. (Wilmington, Massachusetts)
INVENTOR(S) Yosef Stein (Sharon, Massachusetts);  Seth S. Kessler (Newton, Massachusetts);  Haim Primo (Ganei Tikva, Israel)
ABSTRACT Aspects of the present application allow for measurement of a calibrated resistance for a resistive film in a sensing element, such that effects from contact resistance and background resistance drifts due to factors such as temperature, strain or aging can be reduced or eliminated. In some embodiments, by taking a plurality of two-terminal resistance measurements between various pairs of electrodes on a resistive film, a contact-resistance-independent resistance of a reference portion of the resistive film can be determined. Further, a contact-resistance-independent resistance of a sensing portion of the resistive film can be determined based on a plurality of two-terminal resistance measurements between pairs of electrodes. The resistance of the reference portion can be removed from the measured resistance of the sensing portion, such that variations in the reference portion resistance that are not caused by a sensed environmental condition may be compensated.
FILED Friday, June 11, 2021
APPL NO 17/346049
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/20 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656386 Kildishev et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Alexander V. Kildishev (West Lafayette, Indiana);  Di Wang (West Lafayette, Indiana);  Zhaxylyk A. Kudyshev (West Lafayette, Indiana);  Maowen Song (West Lafayette, Indiana);  Alexandra Boltasseva (West Lafayette, Indiana);  Vladimir M. Shalaev (West Lafayette, Indiana)
ABSTRACT A plasmonic system is disclosed. The system includes at least one polarizer that is configured to provide at least one linearly polarized broadband light beam, an anisotropic plasmonic metasurface (APM) assembly having a plurality of nanoantennae each having a predetermined orientation with respect to a global axis representing encoded digital data, the APM assembly configured to receive the at least one linearly polarized broadband light beam and by applying localized surface plasmon resonance reflect light with selectable wavelengths associated with the predetermined orientations of the nanoantennae, and at least one analyzer that is configured to receive the reflected light with selectable wavelength, wherein the relative angles between each of the at least one analyzers and each of the at least one polarizers are selectable with respect to the global axis, thereby allowing decoding of the digital data.
FILED Wednesday, April 07, 2021
APPL NO 17/224338
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/008 (20130101) Original (OR) Class

Information Storage Based on Relative Movement Between Record Carrier and Transducer
G11B 7/125 (20130101)
G11B 7/1381 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656452 Gao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Magic Leap, Inc. (Plantation, Florida)
ASSIGNEE(S) Magic Leap, Inc. (Plantation, Florida)
INVENTOR(S) Chunyu Gao (Tucson, Arizona);  Yuxiang Lin (Tucson, Arizona);  Hong Hua (Tucson, Arizona)
ABSTRACT The present invention comprises a compact optical see-through head-mounted display capable of combining, a see-through image path with a virtual image path such that the opaqueness of the see-through image path can be modulated and the virtual image occludes parts of the see-through image and vice versa.
FILED Friday, December 18, 2020
APPL NO 17/127316
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/04 (20130101)
G02B 13/06 (20130101)
G02B 25/001 (20130101)
G02B 26/00 (20130101) Original (OR) Class
G02B 27/144 (20130101)
G02B 27/0172 (20130101)
G02B 27/283 (20130101)
G02B 27/1066 (20130101)
G02B 2027/015 (20130101)
G02B 2027/0118 (20130101)
G02B 2027/0145 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 37/02 (20130101)

Image Data Processing or Generation, in General
G06T 19/006 (20130101)

Pictorial Communication, e.g Television
H04N 23/45 (20230101)
H04N 23/698 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656484 Lee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Somin Eunice Lee (Ann Arbor, Michigan);  Yipei Wang (Ann Arbor, Michigan);  Yunbo Liu (Ann Arbor, Michigan)
ABSTRACT Precise polarimetric imaging of polarization-sensitive nanoparticles is essential to resolving their accurate spatial positions beyond the diffraction limit. However, conventional technologies typically employ mechanically rotated optical components, causing beam deviation errors that cannot be corrected beyond the diffraction limit. To overcome this limitation, a spatially stable nano-imaging system is presented for polarization-sensitive nanoparticles. In this disclosure, it is demonstrated that by integrating a voltage-tunable polarizer into optical microscopy, one is able to achieve high precision nano-imaging without mechanically induced image shift. It is also demonstrated that by integrating a voltage-tunable polarizer into photographic imaging system, one can achieve high-speed suppression of reflection glare and/or high-speed variation light exposure to the imager. By applying amplitude-modulated voltages, high-speed rotation of the transmission polarization and/or modulation of transmission intensity can be achieved for dynamic polarimetric nano-imaging. In addition, it is also demonstrated that by integrating a voltage-tunable polarizer into a photographic camera system, one is able to remove glare from object surfaces for providing images with more contrast, and control the variable light exposure as a variable neutral density filter.
FILED Friday, November 09, 2018
APPL NO 16/761826
ART UNIT 2871 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/3025 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0136 (20130101) Original (OR) Class
G02F 1/13471 (20130101)
G02F 1/133531 (20210101)
G02F 1/133638 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656662 Steely, Jr. et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Simon C. Steely, Jr. (Hudson, New Hampshire);  Richard Dischler (Bolton, Massachusetts);  David Bach (Shrewsbury, Massachusetts);  Olivier Franza (Brookline, Massachusetts);  William J. Butera (Newton, Massachusetts);  Christian Karl (Hudson, Massachusetts);  Benjamin Keen (Minneapolis, Minnesota);  Brian Leung (Quincy, Massachusetts)
ABSTRACT Embodiments herein may present an integrated circuit or a computing system having an integrated circuit, where the integrated circuit includes a physical network layer, a physical computing layer, and a physical memory layer, each having a set of dies, and a die including multiple tiles. The physical network layer further includes one or more signal pathways dynamically configurable between multiple pre-defined interconnect topologies for the multiple tiles, where each topology of the multiple pre-defined interconnect topologies corresponds to a communication pattern related to a workload. At least a tile in the physical computing layer is further arranged to move data to another tile in the physical computing layer or a storage cell of the physical memory layer through the one or more signal pathways in the physical network layer. Other embodiments may be described and/or claimed.
FILED Thursday, February 11, 2021
APPL NO 17/174106
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Electric Digital Data Processing
G06F 1/183 (20130101) Original (OR) Class
G06F 9/5027 (20130101)
G06F 15/76 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/5384 (20130101)
H01L 23/5385 (20130101)
H01L 23/5386 (20130101)
H01L 25/0657 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656927 Rosenkranz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Joshua M Rosenkranz (White Plains, New York);  Pranita Sharad Dewan (New York, New York);  Mudhakar Srivatsa (White Plains, New York);  Praveen Jayachandran (Bangalore, India);  Chander Govindarajan (Chennai, India);  Priyanka Prakash Naik (Mumbai, India);  Kavya Govindarajan (Chennai, India)
ABSTRACT An ensemble of autoencoder models can be trained using different seeds. The trained ensemble of autoencoder models can be run on new time series data to generate a prediction associated with the new time series data. The new time series data can include multiple dimensions per time step. Reconstruction errors can be determined for the prediction. Dimensions having highest reconstruction errors can be selected among the multiple dimensions based on a threshold. The prediction can be segmented based on bursts of the reconstruction errors over time, where temporal segments can be obtained. At least one common pattern including a set of dimensions among the selected dimensions across the temporal segments can be obtained to represent a failure fingerprint.
FILED Friday, December 03, 2021
APPL NO 17/541453
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/076 (20130101) Original (OR) Class
G06F 11/079 (20130101)
G06F 11/0709 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657127 Bhunia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Swarup Bhunia (Gainesville, Florida);  Md Moshiur Rahman (Gainesville, Florida);  Abdulrahman Alaql (Gainesville, Florida)
ABSTRACT The present disclosure describes exemplary methods and systems of protecting an integrated circuit. One exemplary method comprises receiving a plurality of key inputs for enabling operation of the integrated circuit; determining whether the received key inputs are correct key inputs for enabling operation of the integrated circuit; and if the received key inputs are determined to be incorrect key inputs, locking sequential logic and combinational logic of the integrated circuit until correct key inputs are received.
FILED Monday, December 14, 2020
APPL NO 17/120778
ART UNIT 2432 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 9/4498 (20180201)
G06F 21/14 (20130101) Original (OR) Class
G06F 21/75 (20130101)
G06F 21/602 (20130101)
G06F 30/327 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657312 Akhalwaya et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Ismail Yunus Akhalwaya (Emmarentia, South Africa);  Kenneth Clarkson (Madison, New Jersey);  Lior Horesh (North Salem, New York);  Mark S. Squillante (Greenwich, Connecticut);  Shashanka Ubaru (Ossining, New York);  Vasileios Kalantzis (White Plains, New York)
ABSTRACT Techniques and a system to facilitate estimation of a quantum phase, and more specifically, to facilitate estimation of an expectation value of a quantum state, by utilizing a hybrid of quantum and classical methods are provided. In one example, a system is provided. The system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can include an encoding component and a learning component. The encoding component can encode an expectation value associated with a quantum state. The learning component can utilize stochastic inference to determine the expectation value based on an uncollapsed eigenvalue pair.
FILED Friday, January 31, 2020
APPL NO 16/778878
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Electric Digital Data Processing
G06F 17/11 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657314 Xiong et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Chi Xiong (Yorktown Heights, New York);  Jason S. Orcutt (Katonah, New York);  Ricardo Alves Donaton (Cortlandt Manor, New York);  Stephen M. Gates (Ossining, New York);  Swetha Kamlapurkar (Yorktown Heights, New York);  Abram L Falk (Port Chester, New York)
ABSTRACT Techniques regarding microwave-to-optical quantum transducers are provided. For example, one or more embodiments described herein can include an apparatus that can include a microwave resonator on a dielectric substrate and adjacent to an optical resonator, and a photon barrier structure at least partially surrounding an optical resonator, wherein the photon barrier structure is configured to provide isolation of the microwave resonator from optical photons in the dielectric substrate outside the photon barrier structure.
FILED Wednesday, March 03, 2021
APPL NO 17/191178
ART UNIT 2874 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0356 (20130101)
G02F 2203/15 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658256 Derkacs et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) SolAero Technologies Corp. (Albuquerque, New Mexico)
ASSIGNEE(S) SolAero Technologies Corp. (Albuquerque, New Mexico)
INVENTOR(S) Daniel Derkacs (Albuquerque, New Mexico);  John Hart (Albuquerque, New Mexico);  Zachary Bittner (Albuquerque, New Mexico)
ABSTRACT A multijunction solar cell including an upper first solar subcell having a first band gap and positioned for receiving an incoming light beam; a second solar subcell disposed below and adjacent to and lattice matched with said upper first solar subcell, and having a second band gap smaller than said first band gap; wherein at least one of the solar cells has a graded band gap throughout its thickness.
FILED Monday, December 07, 2020
APPL NO 17/114158
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0725 (20130101) Original (OR) Class
H01L 31/0735 (20130101)
H01L 31/1844 (20130101)
H01L 31/1892 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658331 Yushin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Sila Nanotechnologies Inc. (Alameda, California)
ASSIGNEE(S) SILA NANOTECHNOLOGIES, INC. (Alameda, California);  GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
INVENTOR(S) Gleb Yushin (Atlanta, Georgia);  Feixiang Wu (Atlanta, Georgia);  Hyea Kim (Atlanta, Georgia)
ABSTRACT Lithium-ion batteries are provided that variously comprise anode and cathode electrodes, an electrolyte, a separator, and, in some designs, a protective layer. In some designs, at least one of the electrodes may comprise a composite of (i) Li2S and (ii) conductive carbon that is embedded in the core of the composite. In some designs, the protective layer may be disposed on at least one of the electrodes via electrolyte decomposition. Various methods of fabrication for lithium-ion battery electrodes and particles are also provided.
FILED Monday, January 31, 2022
APPL NO 17/649418
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/136 (20130101)
H01M 4/366 (20130101)
H01M 4/0404 (20130101)
H01M 4/0428 (20130101)
H01M 4/0471 (20130101)
H01M 4/1397 (20130101)
H01M 4/5815 (20130101)
H01M 10/052 (20130101) Original (OR) Class
H01M 10/0568 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/70 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 156/10 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658350 Tomar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Vikas Tomar (West Lafayette, Indiana);  Thomas Edward Adams (West Lafayette, Indiana);  Jonathan E. Alvarado (San Diego, California);  James Eric Dietz (Lafayette, Indiana);  Bing Li (West Lafayette, Indiana);  Christian T. Neal (Pittsburgh, Pennsylvania)
ABSTRACT Various implementations of a smart battery management system are provided. An example method includes identifying sensor data of a cell in a battery system; predicting, based on the sensor data, a failure event of the cell; and preventing the failure event by activating a control circuit connected to the cell.
FILED Thursday, February 27, 2020
APPL NO 16/803127
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 53/63 (20190201)
B60L 58/12 (20190201)
B60L 58/24 (20190201)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/482 (20130101)
H01M 10/486 (20130101)
H01M 10/4257 (20130101) Original (OR) Class
H01M 50/574 (20210101)
H01M 2010/4278 (20130101)
H01M 2220/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658361 Evans et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) Aspen Aerogels, Inc. (Northborough, Massachusetts)
ASSIGNEE(S) Aspen Aerogels, Inc. (Northborough, Massachusetts)
INVENTOR(S) Owen Richard Evans (Chelmsford, Massachusetts);  Nicholas Anthony Zafiropoulos (Wayland, Massachusetts);  Shannon Olga White (Bolton, Massachusetts);  Wenting Dong (Marlborough, Massachusetts);  Wendell E. Rhine (Belmont, Massachusetts)
ABSTRACT The present invention provides a fiber-reinforced aerogel material which can be used as insulation in thermal battery applications. The fiber-reinforced aerogel material is highly durable, flexible, and has a thermal performance that exceeds the insulation materials currently used in thermal battery applications. The fiber-reinforced aerogel insulation material can be as thin as 1 mm less, and can have a thickness variation as low as 2% or less. Also provided is a method for improving the performance of a thermal battery by incorporating a reinforced aerogel material into the thermal battery. Further provided is a casting method for producing thin fiber-reinforced aerogel materials.
FILED Friday, May 06, 2022
APPL NO 17/738861
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/0091 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 6/36 (20130101)
H01M 6/5072 (20130101)
H01M 50/116 (20210101)
H01M 50/117 (20210101)
H01M 50/121 (20210101)
H01M 50/122 (20210101)
H01M 50/124 (20210101)
H01M 50/131 (20210101)
H01M 50/133 (20210101)
H01M 50/138 (20210101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658450 Keyser et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) US Gov't as represented by Sec'y of Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Christian Keyser (Shalimar, Florida);  Trevor Courtney (Niceville, Florida);  John Timler (River Ridge, Louisiana);  David M Barrett (Westminister, Maryland)
ABSTRACT A cylindrical electrode module of a fiber optic laser system includes an inner cylinder having an inner repeating pattern of longitudinally-aligned positive and negative electrodes on an outer surface of the inner cylinder. The cylindrical electrode mode includes an outer cylinder that encloses the inner cylinder. The outer cylinder that has an outer repeating pattern of longitudinally-aligned negative and positive electrodes on an inner surface of the inner cylinder that are in corresponding and complementary, parallel alignment with the positive and negative electrodes of the inner repeating pattern on the outer surface of the inner cylinder. The cylindrical electrode module includes an optical fiber having an input end configured to align with and be optically coupled to a pump laser. The optical fiber is wrapped around the inner cylinder within the outer cylinder to form a cylindrical fiber assembly. The electrodes are activated to achieve quasi-phase matching.
FILED Tuesday, February 15, 2022
APPL NO 17/671962
ART UNIT 2874 — Optics
CURRENT CPC
Manufacture, Shaping, or Supplementary Processes
C03B 2203/16 (20130101)
C03B 2203/42 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/0005 (20130101)
G02B 6/02328 (20130101)
G02B 6/4296 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0385 (20130101) Original (OR) Class
H01S 5/1003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658461 Liu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Quantum Valley Ideas Laboratories (Waterloo, Canada)
ASSIGNEE(S) Quantum Valley Ideas Laboratories (Waterloo, Canada)
INVENTOR(S) Chang Liu (Waterloo, Canada);  Kent Arnold Nickerson (Waterloo, Canada);  Mojtaba Hajialamdari (Waterloo, Canada);  James P. Shaffer (Kitchener, Canada)
ABSTRACT In a general aspect, a laser system includes a laser and a frequency comb generator system. The laser is configured to generate a laser signal, and the frequency comb generator system is configured to generate a frequency comb based on the laser signal. The frequency comb includes frequency comb signals at respective comb frequencies. The laser system also includes a frequency comb dispersion system configured to spatially separate the frequency comb signals onto respective optical channels of the frequency comb dispersion system. The laser system additionally includes a frequency selector system configured to generate a selected frequency signal from the frequency comb signals after separation. The selected frequency signal includes a target separated frequency comb signal. The laser system also includes a frequency shifter configured to alter the selected frequency signal toward a target output frequency of the laser system.
FILED Wednesday, January 04, 2023
APPL NO 18/150110
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/065 (20130101)
H01S 5/0085 (20130101)
H01S 5/0687 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658663 Gaul et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska);  INTEL CORPORATION (Santa Clara, California);  Board OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Nishtha Sharma Gaul (Richardson, Texas);  Andrew Marshall (Dallas, Texas);  Peter A. Dowben (Crete, Nebraska);  Dmitri E. Nikonov (Beaverton, Oregon)
ABSTRACT A magneto-electric (ME) inverter includes two anti-ferromagnetic spin orbit read (AFSOR) circuit elements, each AFSOR circuit element has a CMOS inverter; and an AFSOR device with a ME base layer; a semiconductor channel layer on the ME base layer and comprising a source terminal and a drain terminal, where the source terminal is coupled to an output of the CMOS inverter; and a gate electrode on the semiconductor channel layer. The gate electrode of a second AFSOR device of the two AFSOR circuit elements is coupled to the drain terminal of a first AFSOR device of the two AFSOR circuit elements.
FILED Sunday, May 29, 2022
APPL NO 17/827747
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/42312 (20130101)

Pulse Technique
H03K 19/10 (20130101)
H03K 19/16 (20130101) Original (OR) Class
H03K 19/21 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11659670 McDowell
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Navy Engineering Logistics Office (NELO)
APPLICANT(S) CACI, Inc. Federal (Arlington, Virginia)
ASSIGNEE(S) CACI, Inc. Federal (Reston, Virginia)
INVENTOR(S) David McDowell (Arlington, Virginia)
ABSTRACT The present application describes apparatuses, systems, and methods for robust, adaptable, and deployable computing devices and radio systems. In one aspect, the present application describes a chassis for housing electronic componentry. The chassis includes a frame with a top plate and a bottom plate, an interface panel located on the chassis frame; a back panel located on the chassis frame opposite the interface panel, and a protective protrusion located at a corner of the chassis frame extending beyond the top plate and the bottom plate.
FILED Friday, April 30, 2021
APPL NO 17/245003
ART UNIT 2847 — Electrical Circuits and Systems
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 15/02 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 5/04 (20130101)
H05K 5/06 (20130101)
H05K 5/023 (20130101)
H05K 5/0204 (20130101)
H05K 5/0213 (20130101) Original (OR) Class
H05K 5/0247 (20130101)
H05K 7/20145 (20130101)
H05K 7/20336 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11654117 Steinmetz et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Nicole F. Steinmetz (San Diego, California);  Jonathan Pokorski (San Diego, California)
ABSTRACT A melt processed viral nanoparticle construct for delivery of virus or virus-like particles to a site of interest includes a degradable polymer matrix and a plurality of virus or virus-like particles encapsulated within the degradable polymer matrix. The nanoparticle construct upon administration to the site of interest providing a sustained release of the virus or virus-like particles and/or nanoparticles upon degradation of the polymer matrix.
FILED Friday, November 03, 2017
APPL NO 16/347503
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0021 (20130101)
A61K 9/5153 (20130101)
A61K 9/5184 (20130101) Original (OR) Class
A61K 2039/5258 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/18071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654204 Steinmetz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Nicole Steinmetz (San Diego, California);  Michael Bruckman (Cleveland, Ohio)
ABSTRACT A rod-shaped plant virus having an interior surface and an exterior surface, and at least one imaging agent that is linked to the interior and/or exterior surface is described. The rod-shaped viruses can be combined into larger spherical nanoparticles. A rod-shaped plant virus or spherical nanoparticles including an imaging agent can be used in a method of generating an image of a tissue region of a subject such as a tumor or atherosclerotic tissue by administering the virus particle to the subject and generating an image of the tissue region of the subject to which the virus particle has been distributed.
FILED Tuesday, June 01, 2021
APPL NO 17/335557
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/1884 (20130101)
A61K 49/1896 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/00031 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654402 Bruening et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
ASSIGNEE(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan)
INVENTOR(S) Merlin L. Bruening (East Lansing, Michigan);  Salinda Wijeratne (East Lansing, Michigan);  Wenjing Ning (East Lansing, Michigan);  Jinlan Dong (East Lansing, Michigan);  Weijing Liu (East Lansing, Michigan)
ABSTRACT The disclosure relates to processes, related polyacid polymers, and related articles for functionalizing a porous membrane by contacting the membrane with a polyacid polymer at low pH to stably adsorb a polyacid layer on the membrane pore surface, in particular polyacid polymers including repeating units with a pendent metal-binding ligand or star polyacid polymers. The resulting functionalized membrane is characterized by a high density of free acid groups, resulting in a higher specific capacity for its intended application. The process allows functionalization of porous membranes in a very simple, one-step process, for example without a need to derivatize an adsorbed polyacid layer to impart metal-binding ligand functionality thereto. Such functional membranes may find multiple uses, including rapid, selective binding of proteins for their purification or immobilization.
FILED Tuesday, September 15, 2020
APPL NO 17/021105
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 67/0088 (20130101)
B01D 67/0093 (20130101)
B01D 69/02 (20130101)
B01D 69/141 (20130101)
B01D 69/142 (20130101) Original (OR) Class
B01D 69/144 (20130101)
B01D 71/38 (20130101)
B01D 71/40 (20130101)
B01D 71/60 (20130101)
B01D 71/64 (20130101)
B01D 71/82 (20130101)

Compositions of Macromolecular Compounds
C08L 73/02 (20130101)
C08L 77/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654404 Swager et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy M. Swager (Newton, Massachusetts);  Sara N. Nagelberg (Somerville, Massachusetts);  Mathias Kolle (Hull, Massachusetts);  Lukas Zeininger (Berlin, Germany);  Kent Harvey (South Boston, Massachusetts);  Myles Herbert (Somerville, Massachusetts)
ABSTRACT Embodiments described herein may be useful for optofluidic devices. For example, optofluidic devices using dynamic fluid lens materials represent an ideal platform to create versatile, reconfigurable, refractive optical components. For example, the articles described herein may be useful as fluidic tunable compound micro-lenses. Such compound micro-lenses may be composed of two or more components (e.g., two or more inner phases) that form stable bi-phase emulsion droplets in outer phases (e.g., aqueous media). In some embodiments, the articles described herein may be useful as light emitting droplets. Advantageously, the plurality of droplets may be configured such that light rays may modified (e.g., via stimulation of the droplets, exposure to an analyte such as a pathogen) to have a detectable emission intensity and/or angle of maximum emission intensity under a particular set of conditions.
FILED Friday, May 17, 2019
APPL NO 16/415353
ART UNIT 2884 — Optics
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 23/41 (20220101) Original (OR) Class
B01F 23/4145 (20220101)
B01F 25/14 (20220101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502784 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/25 (20130101)
G01N 21/47 (20130101)
G01N 21/55 (20130101)
G01N 21/59 (20130101)
G01N 21/1717 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654429 Cunningham et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Brian T. Cunningham (Champaign, Illinois);  Rashid Bashir (Champaign, Illinois);  Anurup Ganguli (Urbana, Illinois);  Akid Ornob (Champaign, Illinois);  Gregory Damhorst (Elgin, Illinois);  Hojeong Yu (Savoy, Illinois);  Weili Chen (Sunnyvale, California);  Fu Sun (Urbana, Illinois)
ABSTRACT A sample carrier may include a sample preparation module and an amplification module. A sample mixes with a lysis medium and a nucleic acid amplification medium in the sample preparation module and then flows into a plurality of microfluidic chambers in the amplification module. The microfluidic chambers have disposed therein primers configured to initiate amplification of one or more target nucleic acid sequences corresponding to one or more pathogens. The sample carrier is inserted into an apparatus that includes a plurality of Sight sources and a camera. The light sources illuminate the microfluidic chambers with excitation light, a fluorophore emits fluorescence light indicative of nucleic acid amplification in response to the excitation-light, and the camera captures images of the microfluidic chambers. A target nucleic acid sequence in the sample is indicated by the images showing an increasing fluorescence in a microfluidic chamber that has the primers for that sequence.
FILED Tuesday, March 20, 2018
APPL NO 16/495614
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101) Original (OR) Class
B01L 7/52 (20130101)
B01L 2200/10 (20130101)
B01L 2200/16 (20130101)
B01L 2300/06 (20130101)
B01L 2300/0809 (20130101)
B01L 2300/1805 (20130101)
B01L 2400/06 (20130101)
B01L 2400/0487 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6844 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/01 (20130101)
G01N 21/6428 (20130101)
G01N 21/6452 (20130101)
G01N 21/6456 (20130101)
G01N 2021/6439 (20130101)
G01N 2021/6471 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654612 Fernandez-Nieves et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Alberto Fernandez-Nieves (Suwanee, Georgia);  Thomas Ettor Angelini (Gainesville, Florida);  Ya-Wen Chang (Alpharetta, Georgia);  Samantha M. Marquez (New Haven, Connecticut)
ABSTRACT A method or apparatus for three-dimensionally printing. The method may comprise causing a phase change in a region of the first material by applying focused energy to the region using a focused energy source, and displacing the first material with a second material. The apparatus may comprise a container configured to hold a first material, a focused energy source configured to cause a phase change in a region of the first material by applying focused energy to the region, and an injector configured to displace the first material with a second material. The first material may comprise a yield stress material, which is a material exhibiting Herschel-Bulkley behavior. The yield stress material may comprise a soft granular gel. The second material may comprise one or more cells.
FILED Friday, November 05, 2021
APPL NO 17/519752
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/40 (20170801)
B29C 64/106 (20170801) Original (OR) Class
B29C 64/153 (20170801)
B29C 64/209 (20170801)
B29C 64/259 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2023/06 (20130101)
B29K 2033/08 (20130101)
B29K 2033/26 (20130101)
B29K 2105/0061 (20130101)
B29K 2105/251 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 70/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655271 Minden et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Jonathan Minden (Pittsburgh, Pennsylvania);  Amber Lucas (Pittsburgh, Pennsylvania)
ABSTRACT Provided herein are methods, reagents, and kits for isolating polypeptides, such as a proteome. Also provided herein is a modified trypsin polypeptide that is resistant to autolysis, and that can be selectively-separated from a biological sample once digestion is complete.
FILED Friday, June 07, 2019
APPL NO 16/972923
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Heterocyclic Compounds
C07D 403/12 (20130101)

Peptides
C07K 1/10 (20130101)
C07K 1/14 (20130101) Original (OR) Class
C07K 19/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/6427 (20130101)

Enzymes
C12Y 304/21004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655377 Chanda et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
ASSIGNEE(S) UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
INVENTOR(S) Debashis Chanda (Oviedo, Florida);  Daniel Franklin (Orlando, Florida);  Pablo Manuel Cencillo Abad (Winter Park, Florida)
ABSTRACT An inorganic paint pigment may include a fluid matrix, and paint flakes carried within the fluid matrix. Each paint flake may include a common aluminum layer having a first major surface and a second major surface opposing the first major surface, a first plasmonic aluminum reflector layer carried by the first major surface, and a second plasmonic aluminum reflector layer carried by the second major surface.
FILED Monday, December 09, 2019
APPL NO 16/707363
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 2/24 (20130101)

Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black;
C09C 1/642 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/004 (20130101) Original (OR) Class
C09D 7/20 (20180101)
C09D 7/70 (20180101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/20 (20130101)
C23C 14/30 (20130101)
C23C 14/588 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655548 Archer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Lynden A. Archer (Ithaca, New York);  Wajdi Issam Al Sadat (Freeville, New York)
ABSTRACT Systems and methods to upgrade a feedstock include a metal/oxygen electrochemical cell having a positive electrode, a negative electrode and an electrolyte in which the cell is configured to produce superoxide. The superoxide can react or complex with a feedstock to upgrade the feedstock.
FILED Monday, June 18, 2018
APPL NO 16/625270
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 3/00 (20130101) Original (OR) Class
C25B 5/00 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/96 (20130101)
H01M 12/08 (20130101)
H01M 2300/0022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655552 Chen et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S) Jingyi Chen (Fayetteville, North Carolina);  Lauren F Greenlee (Fayetteville, Arkansas);  Ryan Manso (Fayetteville, Arkansas);  Prashant Acharya (Fayetteville, North Carolina);  Cameron C Crane (Hiwassee, Arkansas)
ABSTRACT In an aspect, a method of making a composite core-shell nanoparticle comprises forming a nanoparticle core comprising nickel oxide or iron oxide via thermal decomposition of a nickel complex or an iron complex; and forming an oxide shell over the core, the oxide shell comprising nickel, iron or a mixture thereof. In another aspect, a method of making composite nanoparticles comprises providing a mixture comprising nickel complex and iron complex; and thermally decomposing the nickel and iron complexes to provide the composite nanoparticles comprising (Ni,Fe)Ox alloy. In yet another aspect, a composition comprises composite nanoparticles, the composite nanoparticles including a nickel oxide core and oxide shell, the oxide shell comprising a mixture of nickel and iron.
FILED Friday, March 13, 2020
APPL NO 16/818249
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 11/051 (20210101)
C25B 11/091 (20210101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656235 Xiao et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Yi Xiao (Miami, Florida);  Obtin Alkhamis (Miami, Florida);  Haixiang Yu (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Yi Xiao (Miami, Florida);  Obtin Alkhamis (Miami, Florida);  Haixiang Yu (Miami, Florida)
ABSTRACT The subject invention provides materials and methods for single-step detection of target molecules in a sample. The methods and assays of the subject invention employ a dye-displacement strategy, in which aptamers complexed with a cyanine dye for sensitive and rapid detection of targets of interest. In the presence of a target, aptamer-target binding liberates the non-covalently bound aptamer-binding dye, resulting in optical changes that can be observed spectrophotometrically or with the naked eye. The methods and assays of the subject invention enable the colorimetric detection of targets of interest regardless of their structure, sequence, target-binding affinity, and physicochemical properties of their targets.
FILED Saturday, August 07, 2021
APPL NO 17/396663
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/78 (20130101)
G01N 33/583 (20130101)
G01N 33/946 (20130101)
G01N 33/948 (20130101)
G01N 33/9413 (20130101)
G01N 33/9486 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656484 Lee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Somin Eunice Lee (Ann Arbor, Michigan);  Yipei Wang (Ann Arbor, Michigan);  Yunbo Liu (Ann Arbor, Michigan)
ABSTRACT Precise polarimetric imaging of polarization-sensitive nanoparticles is essential to resolving their accurate spatial positions beyond the diffraction limit. However, conventional technologies typically employ mechanically rotated optical components, causing beam deviation errors that cannot be corrected beyond the diffraction limit. To overcome this limitation, a spatially stable nano-imaging system is presented for polarization-sensitive nanoparticles. In this disclosure, it is demonstrated that by integrating a voltage-tunable polarizer into optical microscopy, one is able to achieve high precision nano-imaging without mechanically induced image shift. It is also demonstrated that by integrating a voltage-tunable polarizer into photographic imaging system, one can achieve high-speed suppression of reflection glare and/or high-speed variation light exposure to the imager. By applying amplitude-modulated voltages, high-speed rotation of the transmission polarization and/or modulation of transmission intensity can be achieved for dynamic polarimetric nano-imaging. In addition, it is also demonstrated that by integrating a voltage-tunable polarizer into a photographic camera system, one is able to remove glare from object surfaces for providing images with more contrast, and control the variable light exposure as a variable neutral density filter.
FILED Friday, November 09, 2018
APPL NO 16/761826
ART UNIT 2871 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/3025 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0136 (20130101) Original (OR) Class
G02F 1/13471 (20130101)
G02F 1/133531 (20210101)
G02F 1/133638 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657089 Sequeda et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Juan Federico Sequeda (Austin, Texas);  Wayne Phillip Heideman (Austin, Texas);  Daniel Paul Miranker (Austin, Texas)
ASSIGNEE(S) data.world, Inc. (Austin, Texas)
INVENTOR(S) Juan Federico Sequeda (Austin, Texas);  Wayne Phillip Heideman (Austin, Texas);  Daniel Paul Miranker (Austin, Texas)
ABSTRACT A system and method for creating and editing graph schema data structures in a collaborative, real time graphical editing environment is disclosed. The system and method further operates to integrate external sources of data as components of the graph schema. The system and method outputs definition files for the graph schema data structure and mapping files that enable the population of a graph database.
FILED Saturday, August 31, 2019
APPL NO 16/558076
ART UNIT 2159 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/212 (20190101)
G06F 16/213 (20190101)
G06F 16/367 (20190101)
G06F 16/2438 (20190101)
G06F 16/9024 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657405 Chowdhury et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Sreeja Chowdhury (Gainesville, Florida);  Fatemeh Ganji (Gainesville, Florida);  Nima Maghari (Gainesville, Florida);  Domenic J. Forte (Gainesville, Florida)
ABSTRACT Embodiments of the present disclosure provide methods, systems, apparatus, and computer program products are for detecting whether a suspect component such as an integrated circuit (IC) or a system-on-chip (SoC) is recycled. Specifically, various embodiments involve processing power supply rejection ratio (PSRR) data obtained from a low drop-out regulator (LDO) used for the suspect component using a recycle detection machine learning model to generate a recycle prediction. In particular embodiments, the recycle detection machine learning model is developed based at least in part on degradation of PSRRs of LDOs. Accordingly, a determination is made as to whether the suspect component is recycled based on the recycle prediction. If so, then an indication that the suspect component is recycled is provided.
FILED Tuesday, September 01, 2020
APPL NO 17/008722
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/2851 (20130101)

Electric Digital Data Processing
G06F 21/44 (20130101)
G06F 21/73 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 30/018 (20130101)
G06Q 30/0185 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657523 Chugunov et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey);  KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (Thuwal, Saudi Arabia)
ASSIGNEE(S) The Trustees of Princeton University (Princeton, New Jersey);  King Abdullah University of Science and Technology (Thuwal, Saudi Arabia)
INVENTOR(S) Ilya Chugunov (Princeton, New Jersey);  Seung-Hwan Baek (Princeton, New Jersey);  Qiang Fu (Thuwal, Saudi Arabia);  Wolfgang Heidrich (Thuwal, Saudi Arabia);  Felix Heide (Princeton, New Jersey)
ABSTRACT The microlens amplitude masks for flying pixel removal in time-of-flight imaging includes systems, devices, methods, and instructions for image depth determination, including receiving an image, adding noise to the image, determining a set of correlation images, each correlation image having a varying phase offset, for each pixel of the image, generating a masked pixel by applying a mask array, and for each masked pixel, determining the depth of the masked pixel to generate a depth map for the image on a per pixel basis.
FILED Thursday, March 17, 2022
APPL NO 17/915536
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4816 (20130101)
G01S 7/4912 (20130101)
G01S 17/894 (20200101)

Image Data Processing or Generation, in General
G06T 7/50 (20170101) Original (OR) Class
G06T 2207/10028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657895 Baliga et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) INSTITUTE FOR SYSTEMS BIOLOGY (Seattle, Washington)
ASSIGNEE(S) INSTITUTE FOR SYSTEMS BIOLOGY (Seattle, Washington)
INVENTOR(S) Nitin S. Baliga (Tempe, Arizona);  Christopher L. Plaisier (Tempe, Arizona)
ABSTRACT The invention includes methods and systems for identifying targets for therapeutic intervention for various diseases and conditions; and provides specific materials and methods for treatment of specific diseases and conditions.
FILED Wednesday, May 03, 2017
APPL NO 16/097897
ART UNIT 1672 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 2310/141 (20130101)
C12N 2320/11 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 15/30 (20190201) Original (OR) Class
G16B 25/10 (20190201)
G16B 40/00 (20190201)
G16B 45/00 (20190201)
G16B 50/00 (20190201)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/50 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658213 Chang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Robert P. H. Chang (Glenview, Illinois);  Woongkyu Lee (Evanston, Illinois)
ABSTRACT Superlattices and methods of making them are disclosed herein. The superlattices are prepared by irradiating a sample to prepare an alternating superlattice of layers of a first material and a second material, wherein the ratio of the first deposition rate to the second deposition rate is between 1.0:2.0 and 2.0:1.0. The superlattice comprises a multiplicity of alternating layers, wherein the multiplicity of layers of the first material have a thickness between 0.1 nm and 50.0 nm or the multiplicity of layers of the second material have a thickness between 0.1 nm and 50.0.
FILED Monday, June 24, 2019
APPL NO 17/254499
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02175 (20130101)
H01L 21/02565 (20130101)
H01L 29/24 (20130101)
H01L 29/152 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658267 Rajan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Siddharth Rajan (Columbus, Ohio);  Yuewei Zhang (Columbus, Ohio);  Zane Jamal-Eddine (Columbus, Ohio);  Fatih Akyol (Corum/ Merkez, Turkey)
ABSTRACT An example tunnel junction ultraviolet (UV) light emitting diode (LED) is described herein. The UV LED can include a mesa structure having at least one of: an n-doped bottom contact region, a p-doped region, and a tunnel junction arranged in contact with the p-doped region. Additionally, a geometry of the mesa structure can be configured to increase respective efficiencies of extracting transverse-electric (TE) polarized light and transverse-magnetic (TM) polarized light from the tunnel junction UV LED. The mesa structure can be configured such that an emitted photon travels less than 10 μm before reaching the inclined sidewall.
FILED Tuesday, November 02, 2021
APPL NO 17/516796
ART UNIT 2816 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 33/06 (20130101)
H01L 33/20 (20130101) Original (OR) Class
H01L 33/32 (20130101)
H01L 33/385 (20130101)
H01L 33/405 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658305 Greer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Julia R. Greer (San Marino, California);  Lucas R. Meza (Pasadena, California);  Lauren C. Montemayor (Pasadena, California);  Xun W. Gu (Pasadena, California)
ABSTRACT A scaffold includes struts that intersect at nodes. In some instances, a cross section of the cores has at least one dimension less than 100 microns. The core can be a solid, liquid or a gas. In some instances, one or more shell layers are positioned on the core.
FILED Friday, January 24, 2020
APPL NO 16/752372
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0037 (20130101)
G03F 7/70375 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/26 (20130101)
H01G 11/30 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/72 (20130101) Original (OR) Class
H01M 8/0247 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658612 Naing et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) MUMEC, INC. (Oakland, California)
ASSIGNEE(S) MUMEC, INC. (Oakland, California)
INVENTOR(S) Thura Lin Naing (Union City, California);  Tristan Orion Rocheleau (Berkeley, California)
ABSTRACT The present disclosure provides a super-regenerative transceiver with a feedback element having a controllable gain. The super-regenerative transceiver utilizes the controllable gain to improve RF signal data sensitivity and improve RF signal data capture rates. Super-regenerative transceivers described herein permit signal data capture over a broad range of frequencies and for a range of communication protocols. Super-regenerative transceivers described herein are tunable, consume very little power for operation and maintenance, and permit long term operation even when powered by very small power sources (e.g., coin batteries).
FILED Sunday, January 24, 2021
APPL NO 17/248411
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 5/30 (20130101)
H03B 5/32 (20130101) Original (OR) Class
H03B 5/323 (20130101)
H03B 5/1215 (20130101)

Demodulation or Transference of Modulation From One Carrier to Another
H03D 11/04 (20130101)
H03D 11/08 (20130101)
H03D 2200/0074 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 3/02 (20130101)
H03H 9/02228 (20130101)
H03H 9/02259 (20130101)
H03H 9/02393 (20130101)
H03H 9/2447 (20130101)
H03H 9/2457 (20130101)
H03H 2003/027 (20130101)

Transmission
H04B 1/16 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/127 (20130101)

Wireless Communication Networks
H04W 64/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658663 Gaul et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska);  INTEL CORPORATION (Santa Clara, California);  Board OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Nishtha Sharma Gaul (Richardson, Texas);  Andrew Marshall (Dallas, Texas);  Peter A. Dowben (Crete, Nebraska);  Dmitri E. Nikonov (Beaverton, Oregon)
ABSTRACT A magneto-electric (ME) inverter includes two anti-ferromagnetic spin orbit read (AFSOR) circuit elements, each AFSOR circuit element has a CMOS inverter; and an AFSOR device with a ME base layer; a semiconductor channel layer on the ME base layer and comprising a source terminal and a drain terminal, where the source terminal is coupled to an output of the CMOS inverter; and a gate electrode on the semiconductor channel layer. The gate electrode of a second AFSOR device of the two AFSOR circuit elements is coupled to the drain terminal of a first AFSOR device of the two AFSOR circuit elements.
FILED Sunday, May 29, 2022
APPL NO 17/827747
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/42312 (20130101)

Pulse Technique
H03K 19/10 (20130101)
H03K 19/16 (20130101) Original (OR) Class
H03K 19/21 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658754 Wan et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas);  University of North Texas (Denton, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas);  University of North Texas (Denton, Texas)
INVENTOR(S) Yan Wan (Plano, Texas);  Yixin Gu (Austin, Texas);  Chenyuan He (Austin, Texas);  Songwei Li (Austin, Texas);  Mushuang Liu (Austin, Texas);  Shengli Fu (Austin, Texas)
ABSTRACT The present disclosure presents aerial communication systems and methods. One such system comprises an unmanned aerial vehicle platform and a communication component integrated with the unmanned aerial vehicle platform, wherein the communication component is configured to establish an Air to Air (A2A) communication channel with a remote directional antenna that is integrated with a remote unmanned aerial vehicle platform. The system further includes a computing component integrated with the unmanned aerial vehicle platform, wherein the computing component is configured to determine an optimal heading angle for transmission of communication signals from a directional antenna to the remote directional antenna in an unknown communication environment from received signal strength indicator (RSSI) information obtained from the remote directional antenna. Other systems and methods are also disclosed.
FILED Friday, February 05, 2021
APPL NO 17/168973
ART UNIT 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission
H04B 7/043 (20130101)
H04B 17/318 (20150115) Original (OR) Class
H04B 17/391 (20150115)

Wireless Communication Networks
H04W 4/46 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11654424 Kiplinger et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Jaqueline Loetsch Kiplinger (Los Alamos, New Mexico);  Louis A. Silks (Santa Fe, New Mexico);  Ross James Beattie (Los Alamos, New Mexico)
ABSTRACT The present disclosure is directed to method embodiments for making anhydrous lanthanide halide complexes. At least some embodiments comprise making a lanthanide halide complex by reacting a lanthanide metal oxide with an oxygen scavenger and catalyst in the presence of a donor solvent. The method is selective toward light lanthanide metal oxides and thus further provides a method for separating light lanthanide metal oxides from heavy lanthanide metal oxides, actinide oxides, and non-lanthanide rare earth element oxides.
FILED Wednesday, June 10, 2020
APPL NO 16/898253
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/24 (20130101) Original (OR) Class
B01J 31/226 (20130101)
B01J 31/1805 (20130101)
B01J 31/1815 (20130101)
B01J 31/2269 (20130101)
B01J 37/04 (20130101)
B01J 37/08 (20130101)
B01J 2531/38 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11654913 Sarlashkar et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Southwest Research Institute (San Antonio, Texas)
ASSIGNEE(S) SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas)
INVENTOR(S) Jayant V. Sarlashkar (San Antonio, Texas);  Sankar B. Rengarajan (San Antonio, Texas);  Scott R. Hotz (Pinckney, Michigan);  Stanislav A. Gankov (San Antonio, Texas)
ABSTRACT Vehicle controller circuitry for a subject vehicle to determine vehicle constraints including predicted values for vehicle speed of at least one other vehicle and predicted values of for vehicle position of the at least one other vehicle relative to the subject vehicle, wherein the vehicle constraints are determined at predetermined time steps (k) over a time horizon (Th).
FILED Thursday, March 04, 2021
APPL NO 17/249545
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 30/0956 (20130101)
B60W 30/18159 (20200201) Original (OR) Class
B60W 30/18163 (20130101)
B60W 40/04 (20130101)
B60W 40/105 (20130101)
B60W 40/107 (20130101)
B60W 2554/802 (20200201)
B60W 2554/4041 (20200201)
B60W 2556/65 (20200201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655183 Lange et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Andrew Lange (Livermore, California);  Jay W. Dawson (Livermore, California);  Rebecca Dylla-Spears (Dublin, California);  Cody Wren Mart (Livermore, California);  Michael J. Messerly (Danville, California);  Koroush Sasan (Pleasanton, California);  Nick Schenkel (Livermore, California);  Tayyab I. Suratwala (Pleasanton, California)
ABSTRACT The present disclosure relates to a method for forming a glass, ceramic or composite material. The method may involve initially forming a plurality of tubes and then performing a coating operation to coat the plurality of tubes with materials containing metal or metalloid elements, including inorganic compounds, organometallic compounds, or coordination complexes to form coated tubes. The method may further include performing at least one of a thermal operation or a thermochemical operation on the coated tubes to form a solid glass, ceramic, or composite structure with dimensions representing at least one of a rod or fiber.
FILED Thursday, June 11, 2020
APPL NO 16/899069
ART UNIT 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Manufacture, Shaping, or Supplementary Processes
C03B 37/16 (20130101)
C03B 37/02727 (20130101)

Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 17/3636 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655185 Messerly et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Michael Messerly (Danville, California);  Nicholas Calta (Oakland, California);  Selim Elhadj (Livermore, California);  Andrew Lange (Livermore, California);  Cody Wren Mart (Livermore, California);  Robert Mellors (Livermore, California);  Nick Schenkel (Livermore, California);  Charles Xiao Yu (Pleasanton, California)
ABSTRACT A method is disclosed of making a coated optical fiber. The method may involve drawing a preform through a furnace to create a fiber having a desired diameter and cross sectional shape. The fiber is then drawn through a slurry, wherein the slurry includes elements including at least one of metallic elements, alloy elements or dielectric elements, and the slurry wets an outer surface of the fiber. As the fiber is drawn through the slurry, it is then drawn through a forming die to impart a wet coating having a desired thickness on an outer surface of the fiber. The wet fiber is then drawn through an oven or ovens configured to heat the wet coating sufficiently to produce a consolidated surface coating on the fiber as the fiber exits the oven or ovens.
FILED Friday, April 03, 2020
APPL NO 16/839281
ART UNIT 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Manufacture, Shaping, or Supplementary Processes
C03B 37/15 (20130101)
C03B 37/032 (20130101)

Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 25/18 (20130101)
C03C 25/1063 (20180101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655550 Liang et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Siwei Liang (Dublin, California);  Sarah E. Baker (Dublin, California);  Theodore F. Baumann (Discovery Bay, California);  Eric B. Duoss (Dublin, California);  Christopher M. Spadaccini (Oakland, California);  Cheng Zhu (Livermore, California)
ABSTRACT An ink formulation and electrode that enhances hydrogen production, oxygen production, carbon dioxide reduction and other electrocatalytic reactions. Embodiments include an ink formulation with polymer binders having different catalytical precursors and a 3D electrode produced by additive manufacturing from the inventor's ink formulation. Various embodiments of the inventor's apparatus, systems, and methods provide inks that that are 3D-printed into patterns that optimize surface area and flow. The catalytic materials are imbedded into the ink matrix which is then printed into a 3D structure that has architecture that optimizes surface area and flow properties.
FILED Friday, April 10, 2020
APPL NO 16/845985
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/02 (20130101)
C25B 9/19 (20210101) Original (OR) Class
C25B 11/03 (20130101)
C25B 11/031 (20210101)
C25B 11/089 (20210101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/0656 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/36 (20130101)
Y02E 60/50 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/133 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655738 Roth
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados)
ASSIGNEE(S) DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados)
INVENTOR(S) Gregory Thomas Roth (Davison, Michigan)
ABSTRACT A piston oil squirter is selectively opened when an oil temperature is below a threshold oil temperature to transfer heat from the combustion chamber and heat the oil more rapidly when the engine is cold.
FILED Friday, December 04, 2015
APPL NO 14/958969
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Lubricating of Machines or Engines in General; Lubricating Internal Combustion Engines; Crankcase Ventilating
F01M 1/08 (20130101)
F01M 1/16 (20130101)
F01M 5/001 (20130101)
F01M 5/002 (20130101)
F01M 5/007 (20130101) Original (OR) Class
F01M 5/021 (20130101)

Cooling of Machines or Engines in General; Cooling of Internal-combustion Engines
F01P 3/08 (20130101)
F01P 2025/40 (20130101)
F01P 2037/02 (20130101)
F01P 2060/04 (20130101)

Internal-combustion Piston Engines; Combustion Engines in General
F02B 75/12 (20130101)

Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof
F02M 26/01 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655775 Puente et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Bryan P. Maldonado Puente (Oak Ridge, Tennessee);  Brian C. Kaul (Oak Ridge, Tennessee);  Catherine D. Schuman (Oak Ridge, Tennessee);  John Parker Mitchell (Oak Ridge, Tennessee);  Steven R. Young (Oak Ridge, Tennessee)
ABSTRACT A system that controls a combustion engine stores network vectors in a memory that represent diverse and distinct spiking neural networks. The system decodes the network vectors and trains and evaluates the spiking neural networks. The system duplicates selected network vectors and crosses-over the duplicated network vectors that represent modified spiking neural networks. The system mutates the crossed-over duplicated network vectors by randomly modifying one or more portions of the crossing-over duplicated network vectors. The system meter exhaust gas into an intake manifold when an engine temperature exceeds a threshold, an engine load exceeds a threshold, an engine's rotation-per-minute rate exceeds a threshold, and a fuel flow exceeds a threshold. The system modifies fuel flow into an engine's combustion chamber on a cycle-to-cycle basis by the trained spiking neural network.
FILED Monday, August 15, 2022
APPL NO 17/888047
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Controlling Combustion Engines
F02D 41/0002 (20130101)
F02D 41/022 (20130101)
F02D 41/38 (20130101)
F02D 41/0047 (20130101)
F02D 41/2438 (20130101) Original (OR) Class
F02D 2200/04 (20130101)
F02D 2200/021 (20130101)
F02D 2200/101 (20130101)
F02D 2200/501 (20130101)
F02D 2200/0614 (20130101)

Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines
F02P 5/1502 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/049 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655776 Petrus et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) GM Global Technology Operations LLC (Detroit, Michigan)
ASSIGNEE(S) GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan)
INVENTOR(S) Ronald John Petrus (Lake Orion, Michigan);  Richard M. Nichols, III (Macomb, Michigan);  Brian C. Leuenhagen (Clarkston, Michigan);  William A. Berry (Davison, Michigan);  Qigui Wang (Rochester Hills, Michigan);  James T. Singer (Defiance, Ohio)
ABSTRACT An automobile vehicle engine includes multiple water jackets individually formed in a cast engine block proximate to successive ones of multiple cylinder bores. Multiple cast-in place transition regions are individually formed during a casting operation of the cast engine block at entrances to individual ones of the multiple water jackets. Individual ones of multiple sawcuts open into individual ones of the multiple cast-in place transition regions.
FILED Friday, March 25, 2022
APPL NO 17/704535
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Foundry Moulding
B22C 9/10 (20130101)

Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines
F02F 1/16 (20130101) Original (OR) Class
F02F 2200/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655965 Gladden et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Glint Photonics, Inc. (Burlingame, California)
ASSIGNEE(S) Glint Photonics, Inc. (Burlingame, California)
INVENTOR(S) Christopher Gladden (San Mateo, California);  Andrew Kim (San Jose, California);  Peter Kozodoy (Palo Alto, California);  Barbara Kruse (San Francisco, California)
ABSTRACT A luminaire for providing configurable static lighting or dynamically-adjustable lighting. The luminaire uses an array of focusing elements that act on light provided via a corresponding array of sources or via an edge-lit lightguide. Designs are provided for adjusting the number of distinct beams produced by the luminaire, as well as the angular width, angular profile, and pointing angle of the beams. Designs are also provided for systems utilizing the adjustable luminaires in various applications.
FILED Thursday, September 16, 2021
APPL NO 17/476616
ART UNIT 2875 — Optics
CURRENT CPC
Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for
F21K 9/61 (20160801)

Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for
F21V 5/007 (20130101)
F21V 7/0008 (20130101)
F21V 14/06 (20130101) Original (OR) Class
F21V 17/02 (20130101)

Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted
F21Y 2105/00 (20130101)
F21Y 2115/10 (20160801)

Optical Elements, Systems, or Apparatus
G02B 3/0006 (20130101)
G02B 6/005 (20130101)
G02B 6/0036 (20130101)
G02B 6/0055 (20130101)
G02B 19/0028 (20130101)
G02B 19/0066 (20130101)
G02B 26/08 (20130101)
G02B 26/0875 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656075 Kreitinger et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Bridger Photonics, Inc. (Bozeman, Montana)
ASSIGNEE(S) Bridger Photonics, Inc. (Bozeman, Montana)
INVENTOR(S) Aaron Thomas Kreitinger (Bozeman, Montana);  Michael James Thorpe (Bozeman, Montana)
ABSTRACT Measurement apparatuses and methods are disclosed for generating high-precision and -accuracy gas concentration maps that can be overlaid with 3D topographic images by rapidly scanning one or several modulated laser beams with a spatially-encoded transmitter over a scene to build-up imagery. Independent measurements of the topographic target distance and path-integrated gas concentration are combined to yield a map of the path-averaged concentration between the sensor and each point in the image. This type of image is particularly useful for finding localized regions of elevated (or anomalous) gas concentration making it ideal for large-area leak detection and quantification applications including: oil and gas pipeline monitoring, chemical processing facility monitoring, and environmental monitoring.
FILED Wednesday, August 11, 2021
APPL NO 17/399106
ART UNIT 2896 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 21/20 (20130101) Original (OR) Class

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 15/00 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 3/28 (20130101)
G01M 3/38 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/39 (20130101)
G01N 21/53 (20130101)
G01N 2021/1793 (20130101)
G01N 2021/1795 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 5/00 (20130101)

Image or Video Recognition or Understanding
G06V 20/64 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11657148 Hart et al.
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S) Philip Joseph Hart (Rexford, New York);  Honggang Wang (Clifton Park, New York)
ABSTRACT According to some embodiments, system and methods are provided including receiving, via a communication interface of an event detection and classification module comprising a processor, data from one or more sensors in a system; determining an event occurred based on the received data; applying a coherency similarity process to the received data via a classification module; determining whether the event is an actual event or a mal-doer event based on an output of the classification module; transmitting the determination of the event as the actual or the mal-doer event; and modifying operation of the system based on the transmitted output. Numerous other aspects are provided.
FILED Friday, May 10, 2019
APPL NO 16/409189
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 3/032 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 23/0275 (20130101)

Electric Digital Data Processing
G06F 21/554 (20130101) Original (OR) Class

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 2203/20 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658253 Kuang et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Ping Kuang (Latham, New York);  Shawn Yu Lin (Troy, New York);  Anthony Post (Catskill, New York);  Sajeev Oommen John (Mississauga, Canada);  Sergey Leonidovich Eyderman (Toronto, Canada);  Mei-Li Hsieh (Zhunan Township, Taiwan)
ABSTRACT A high absorption photovoltaic material and method of making the material for use in a solar cell are disclosed. The photovoltaic material includes a surface modified with a layer of repeating photonic crystal structures. The photonic crystal structures are approximately inverse conically shaped and have a curved sidewall that has an approximately Gaussian shape. The photonic crystal structures generally have a high vertical depth and sidewall angle. The structures also have a gradient refractive index profile and exhibit the parallel-to-interface refraction light trapping effect. An anti-reflective coating is disposed over the photonic crystal structure layer. The photovoltaic material exhibits near unity light absorption over a broad range of visible and near infrared wavelengths and incidence angles, even at reduced thicknesses. The photovoltaic structures are formed via a combined photolithography and reactive-ion etching method at low power with a gas mixture having a high ratio of an etchant component to a passivation component.
FILED Wednesday, November 18, 2020
APPL NO 16/951541
ART UNIT 2883 — Optics
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/18 (20130101)
H01L 31/02168 (20130101)
H01L 31/02363 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658258 Steiner
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Myles Aaron Steiner (Denver, Colorado)
ABSTRACT The present disclosure relates to a method that includes depositing a spalling layer onto a surface that includes a substrate, depositing a device comprising a III-V material onto the spalling layer, resulting in the forming of a stack, and dividing the stack substantially at a plane positioned within the spalling layer to form a first portion that includes the substrate and a second portion that includes the PV device, where the spalling layer includes a first layer configured to provide a compressive stress and a second layer configured to provide a tensile stress, the first layer and the second layer form an interface, the dividing occurs as result of the interface, and the compressive stress and the tensile stress are strain-balanced so that a total strain within the spalling layer is approximately zero.
FILED Friday, September 24, 2021
APPL NO 17/484578
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/0392 (20130101)
H01L 31/0735 (20130101)
H01L 31/1844 (20130101)
H01L 31/1892 (20130101) Original (OR) Class
H01L 31/03046 (20130101)
H01L 33/12 (20130101)
H01L 33/30 (20130101)
H01L 33/0062 (20130101)
H01L 33/0093 (20200501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658291 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Hsien-Hau Wang (Downers Grove, Illinois);  Ritesh Jagatramka (Chicago, Illinois);  Samuel Plunkett (Chicago, Illinois);  Larry A. Curtiss (Downers Grove, Illinois);  Khalil Amine (Oakbrook, Illinois)
ABSTRACT An electrochemical device includes a lithium anode having a red poly(benzonitrile) coating covering at least a portion of the anode; a separator and an air cathode comprising reduced graphene oxide over gas diffusion layer; and an electrolyte comprising an ether solvent, benzonitrile, and a lithium salt.
FILED Tuesday, July 28, 2020
APPL NO 16/941249
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/62 (20130101)
H01M 4/134 (20130101)
H01M 4/366 (20130101) Original (OR) Class
H01M 4/382 (20130101)
H01M 4/885 (20130101)
H01M 4/926 (20130101)
H01M 4/8882 (20130101)
H01M 12/08 (20130101)
H01M 2004/027 (20130101)
H01M 2004/028 (20130101)
H01M 2300/0028 (20130101)
H01M 2300/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658298 Lipson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Albert L. Lipson (Forest Park, Illinois);  Jessica L. Durham (Frankfort, Illinois)
ABSTRACT A stabilized lithium metal oxide cathode material comprises microparticles of lithium metal oxide in which individual particles thereof a core of lithium metal oxide and a coating of a different lithium metal oxide surrounding the core. There is an interface layer between the cores and the coatings in which there are gradients of metal ions in the direction of coating to core. The materials are made by a three stage process involving coprecipitating precursor metal hydroxide core particles at a controlled pH; coprecipitating a different metal hydroxide coating on the particles without controlling the pH; and then calcining the resulting coated precursor particles with lithium hydroxide to form the stabilized lithium metal oxide material.
FILED Tuesday, May 19, 2020
APPL NO 16/877925
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/366 (20130101)
H01M 4/0471 (20130101)
H01M 4/525 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 10/0568 (20130101)
H01M 10/0569 (20130101)
H01M 50/40 (20210101)
H01M 2300/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658460 Leisher et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Paul O. Leisher (Dublin, California);  Robert J. Deri (Pleasanton, California);  Susant K. Patra (Brentwood, California)
ABSTRACT The present technology can be used to control the current injection profile in the longitudinal direction of a high-power diode laser in order to optimize current densities as a function of position in the cavity to promote higher reliable output power and increase the electrical to optical conversion efficiency of the device beyond the level which can be achieved without application of this technique. This approach can be utilized, e.g., in the fabrication of semiconductor laser chips to improve the output power and wall plug efficiency for applications requiring improved performance operation.
FILED Tuesday, March 26, 2019
APPL NO 17/041256
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/042 (20130101) Original (OR) Class
H01S 5/343 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11654187 Guerrero et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Felicito Guerrero (Paige, Texas);  Luisa N. Domingues (College Station, Texas)
ABSTRACT Antigenic polypeptides derived from a naturally occurring horn fly protein, and nucleic acid molecules encoding the polypeptides, are described. The polypeptides elicit an immune response which, in turn, produces detrimental effects in horn flies feeding on vaccinated cattle. Thus, the present disclosure provides a novel horn fly vaccine.
FILED Wednesday, February 03, 2021
APPL NO 17/166433
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0003 (20130101) Original (OR) Class
A61K 39/39 (20130101)
A61K 2039/552 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 43/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655447 Talaat
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Adel M. Talaat (Madison, Wisconsin)
ABSTRACT Described herein is a Mycobacterium mutant, comprising at least one mutation in at least one gene sequence encoding global gene regulators (GGRs) selected from the group consisting of sigH, sigL, sigE, ECF-1, and mixtures thereof, wherein the GGR gene is at least partially inactivated. Described herein also is a vaccine based on the mutant and a method of differentiating between subjects that have been infected with Mycobacterium and subjects that have not been infected with Mycobacterium or have been vaccinated with a Mycobacterium vaccine.
FILED Friday, April 02, 2021
APPL NO 17/221605
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/04 (20130101)
A61K 2039/522 (20130101)
A61K 2039/552 (20130101)

Peptides
C07K 14/35 (20130101)
C07K 14/195 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101) Original (OR) Class
C12N 1/36 (20130101)
C12N 1/205 (20210501)
C12N 15/1031 (20130101)
C12N 15/1136 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101)
C12Q 2600/156 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/32 (20210501)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5695 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11655477 Loria et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Rosemary Loria (Gainesville, Florida);  Yucheng Zhang (Gainesville, Florida);  Yousong Ding (Gainesville, Florida);  Guangde Jiang (Gainesville, Florida)
ABSTRACT The present disclosure includes genetically engineered, non-pathogenic Streptomyces bacterium with exogenous, non-native Thaxtomin A (ThxA) biosynthetic gene clusters conferring the genetically engineered, non-pathogenic Streptomyces bacterium with the ability to produce thaxtomin A. Also included are methods of providing thaxtomin producing capability in non-native Streptomyces bacterial strains, methods of producing thaxtomin compounds with the genetically engineered Streptomyces bacteria of the present disclosure, and methods of producing thaxtomin compounds and nitro-tryptophan analogs, and fluorinated thaxtomin compounds, analogs, and intermediates with the genetically engineered Streptomyces bacteria of the present disclosure.
FILED Wednesday, May 23, 2018
APPL NO 16/616059
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/28 (20200101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)
C12N 15/76 (20130101) Original (OR) Class
C12N 2510/02 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 17/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11654157 Grindrod et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Shuttle Pharmaceuticals, Inc. (Rockville, Maryland)
ASSIGNEE(S) Shuttle Pharmaceuticals, Inc. (Rockville, Maryland)
INVENTOR(S) Scott Grindrod (Rockville, Maryland);  Mira Jung (Rockville, Maryland);  Olga Timofeeva (Rockville, Maryland);  Milton Brown (Rockville, Maryland);  Anatoly Dritschilo (Rockville, Maryland)
ABSTRACT Methods and formulations are provided for treating cancer and neoplastic diseases in conjunction with radiation therapy where such methods and formulations include a combination of a radiosensitizing agent that is metabolized by thymidine phosphorylase and a thymidine phosphorylase inhibitor that increases the half-life of the radiosensitizing agent.
FILED Tuesday, January 09, 2018
APPL NO 16/475999
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/513 (20130101)
A61K 31/7072 (20130101) Original (OR) Class
A61K 33/243 (20190101)
A61K 2121/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656172 Knight-Rubino et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Photonics Automation Specialties LLC (Tucson, Arizona)
ASSIGNEE(S) Photonics Automation Specialties LLC (Tucson, Arizona)
INVENTOR(S) Gerard Knight-Rubino (Tucson, Arizona);  Xiyao Zhang (Tucson, Arizona)
ABSTRACT A multichannel angular spectrometer includes an array of fiber pickups having an arcuate arrangement and focused about a sample volume. A broadband light source is configured to illuminate a sample within the sample volume. At least one dispersion element is in optical communication with the array of fiber pickups. An imaging sensor is in optical communication with the array of fiber pickups. The imaging sensor is configured to image the broadband light received by the array of fiber pickups and dispersed by the at least one dispersion element. A processor is in electrical communication with the imaging sensor. The processor has a power supply and computer-readable memory.
FILED Tuesday, June 01, 2021
APPL NO 17/335921
ART UNIT 2896 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/31 (20130101) Original (OR) Class
G01N 2201/08 (20130101)
G01N 2201/0635 (20130101)
G01N 2201/0638 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11656452 Gao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Magic Leap, Inc. (Plantation, Florida)
ASSIGNEE(S) Magic Leap, Inc. (Plantation, Florida)
INVENTOR(S) Chunyu Gao (Tucson, Arizona);  Yuxiang Lin (Tucson, Arizona);  Hong Hua (Tucson, Arizona)
ABSTRACT The present invention comprises a compact optical see-through head-mounted display capable of combining, a see-through image path with a virtual image path such that the opaqueness of the see-through image path can be modulated and the virtual image occludes parts of the see-through image and vice versa.
FILED Friday, December 18, 2020
APPL NO 17/127316
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/04 (20130101)
G02B 13/06 (20130101)
G02B 25/001 (20130101)
G02B 26/00 (20130101) Original (OR) Class
G02B 27/144 (20130101)
G02B 27/0172 (20130101)
G02B 27/283 (20130101)
G02B 27/1066 (20130101)
G02B 2027/015 (20130101)
G02B 2027/0118 (20130101)
G02B 2027/0145 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 37/02 (20130101)

Image Data Processing or Generation, in General
G06T 19/006 (20130101)

Pictorial Communication, e.g Television
H04N 23/45 (20230101)
H04N 23/698 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11656172 Knight-Rubino et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Photonics Automation Specialties LLC (Tucson, Arizona)
ASSIGNEE(S) Photonics Automation Specialties LLC (Tucson, Arizona)
INVENTOR(S) Gerard Knight-Rubino (Tucson, Arizona);  Xiyao Zhang (Tucson, Arizona)
ABSTRACT A multichannel angular spectrometer includes an array of fiber pickups having an arcuate arrangement and focused about a sample volume. A broadband light source is configured to illuminate a sample within the sample volume. At least one dispersion element is in optical communication with the array of fiber pickups. An imaging sensor is in optical communication with the array of fiber pickups. The imaging sensor is configured to image the broadband light received by the array of fiber pickups and dispersed by the at least one dispersion element. A processor is in electrical communication with the imaging sensor. The processor has a power supply and computer-readable memory.
FILED Tuesday, June 01, 2021
APPL NO 17/335921
ART UNIT 2896 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/31 (20130101) Original (OR) Class
G01N 2201/08 (20130101)
G01N 2201/0635 (20130101)
G01N 2201/0638 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11658398 Downey et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) James M. Downey (Cleveland, Ohio);  Bryan L. Schoenholz (Cleveland, Ohio);  Marie T. Piasecki (Cleveland, Ohio)
ABSTRACT A phased-array, conformal antenna and a method for forming same are disclosed. The method comprises forming a substantially planar layered antenna structure by fabricating a printed circuit board (PCB) on a substantially planar first substrate, adhering the PCB to a second substantially planar substrate, the second substantially planar substrate comprising an aerogel, adhering a plurality of antenna elements to the substantially planar second substrate to form the phased-array, adhering a protective layer to the one or more antenna elements, and shaping the substantially planar layered antenna structure to form a substantially curved layered antenna structure.
FILED Monday, August 24, 2020
APPL NO 17/000597
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/02 (20130101)
H01Q 1/40 (20130101)
H01Q 1/286 (20130101) Original (OR) Class
H01Q 3/30 (20130101)
H01Q 9/0414 (20130101)
H01Q 9/0457 (20130101)
H01Q 21/20 (20130101)
H01Q 21/065 (20130101)
H01Q 21/0075 (20130101)
H01Q 21/0087 (20130101)
H01Q 23/00 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/181 (20130101)
H05K 3/0058 (20130101)
H05K 3/305 (20130101)
H05K 2201/09018 (20130101)
H05K 2201/10098 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11658663 Gaul et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska);  INTEL CORPORATION (Santa Clara, California);  Board OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Nishtha Sharma Gaul (Richardson, Texas);  Andrew Marshall (Dallas, Texas);  Peter A. Dowben (Crete, Nebraska);  Dmitri E. Nikonov (Beaverton, Oregon)
ABSTRACT A magneto-electric (ME) inverter includes two anti-ferromagnetic spin orbit read (AFSOR) circuit elements, each AFSOR circuit element has a CMOS inverter; and an AFSOR device with a ME base layer; a semiconductor channel layer on the ME base layer and comprising a source terminal and a drain terminal, where the source terminal is coupled to an output of the CMOS inverter; and a gate electrode on the semiconductor channel layer. The gate electrode of a second AFSOR device of the two AFSOR circuit elements is coupled to the drain terminal of a first AFSOR device of the two AFSOR circuit elements.
FILED Sunday, May 29, 2022
APPL NO 17/827747
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/42312 (20130101)

Pulse Technique
H03K 19/10 (20130101)
H03K 19/16 (20130101) Original (OR) Class
H03K 19/21 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11655051 Washington, II et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) William J. Washington, II (North Potomac, Maryland);  Christian Jordan (Baltimore, Maryland)
ABSTRACT A bag unlocking method includes receiving, by a bag handling system, a bag during a check-in process. The bag handling system identifies, from a travel carrier system, traveler information corresponding to the bag. A securing device of the bag is programmed, using an unlock code pertaining to the traveler information. The bag handling system reads a bag tag of the bag at a baggage inspection station and determines the unlock code pertaining to the bag tag. The bag handling system transmits the unlock code to cause the securing device to unlock at the baggage inspection station.
FILED Tuesday, August 02, 2022
APPL NO 17/879427
ART UNIT 2876 — Optics
CURRENT CPC
Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for
B64F 1/366 (20130101) Original (OR) Class
B64F 1/368 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11654311 Goldish et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia);  Fraunhofer-Gesellschaft zur Foerdrung der angewandten Forschung e. V. (Munich, Germany)
ASSIGNEE(S) United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia);  Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e. V. (Munich, Germany)
INVENTOR(S) Gary Goldish (Minneapolis, Minnesota);  Andrew Hansen (Minneapolis, Minnesota);  Stuart R. Fairhurst (Minneapolis, Minnesota);  Gregory O. Voss (Apple Valley, Minnesota);  Urs Schneider (Munich, Germany)
ABSTRACT A trunk control system having a harness assembly and a flexion control assembly. The harness assembly has a backrest member and a harness secured to the backrest member. The backrest member is configured to be moveably coupled to a wheelchair. The backrest member is selectively moveable about and between a fully retracted position and a fully extended position. The harness cooperates with the backrest member to define a receiving space for receiving at least a portion of a torso of a wheelchair user. The flexion control assembly is coupled to the backrest member of the harness assembly. The flexion control assembly is configured to selectively permit or restrict movement of the backrest member about and between the fully retracted position and the fully extended position.
FILED Tuesday, April 14, 2020
APPL NO 16/848303
ART UNIT 3636 — Static Structures, Supports and Furniture
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 5/3792 (20130101)

Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices
A61G 5/10 (20130101)

Devices, Apparatus or Methods for Life-saving
A62B 35/0012 (20130101) Original (OR) Class
A62B 35/0075 (20130101)

Seats Specially Adapted for Vehicles; Vehicle Passenger Accommodation Not Otherwise Provided for
B60N 2/245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11656662 Steely, Jr. et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Simon C. Steely, Jr. (Hudson, New Hampshire);  Richard Dischler (Bolton, Massachusetts);  David Bach (Shrewsbury, Massachusetts);  Olivier Franza (Brookline, Massachusetts);  William J. Butera (Newton, Massachusetts);  Christian Karl (Hudson, Massachusetts);  Benjamin Keen (Minneapolis, Minnesota);  Brian Leung (Quincy, Massachusetts)
ABSTRACT Embodiments herein may present an integrated circuit or a computing system having an integrated circuit, where the integrated circuit includes a physical network layer, a physical computing layer, and a physical memory layer, each having a set of dies, and a die including multiple tiles. The physical network layer further includes one or more signal pathways dynamically configurable between multiple pre-defined interconnect topologies for the multiple tiles, where each topology of the multiple pre-defined interconnect topologies corresponds to a communication pattern related to a workload. At least a tile in the physical computing layer is further arranged to move data to another tile in the physical computing layer or a storage cell of the physical memory layer through the one or more signal pathways in the physical network layer. Other embodiments may be described and/or claimed.
FILED Thursday, February 11, 2021
APPL NO 17/174106
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Electric Digital Data Processing
G06F 1/183 (20130101) Original (OR) Class
G06F 9/5027 (20130101)
G06F 15/76 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/5384 (20130101)
H01L 23/5385 (20130101)
H01L 23/5386 (20130101)
H01L 25/0657 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11653834 Hillman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Non-Profit Organization (NPO)
Wallace H Coulter Foundation (WHCF)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Elizabeth Marjorie Clare Hillman (New York, New York);  Sean A. Burgess (New York, New York)
ABSTRACT Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM).
FILED Tuesday, August 31, 2021
APPL NO 17/462824
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0064 (20130101) Original (OR) Class
A61B 5/0066 (20130101)
A61B 5/0071 (20130101)
A61B 5/0073 (20130101)
A61B 5/0075 (20130101)
A61B 5/0088 (20130101)
A61B 5/444 (20130101)
A61B 5/445 (20130101)
A61B 2562/0238 (20130101)
A61B 2562/0242 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/42 (20130101)
G01J 3/457 (20130101)
G01J 3/2889 (20130101)

Optical Elements, Systems, or Apparatus
G02B 23/2476 (20130101)
G02B 26/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11655722 Szul et al.
FUNDED BY
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Dale Szul (West Chester, Ohio);  Donald M. Corsmeier (West Chester, Ohio);  Bernard J. Renggli (Cincinnati, Ohio);  Andrew Keppeler (Mason, Ohio);  Steven Kirgiss (Fairfield, Ohio)
ABSTRACT Apparatuses and methods are provided herein useful to sealing a dynamic gap between a moveable flap and a sidewall. The apparatus may be a seal assembly that includes a spring body, a clip coupled to a distal end of the spring body, and a wear shoe coupled to the clip. The spring body includes a flap arm adjacent the flap and a wall arm adjacent the sidewall. The flap arm and the wall arm bias away from one another when under compression in the gap. A distal end of the wall arm includes a first knuckle and a second knuckle that are pivotally coupled to the clip to create a hinge feature. The wear shoe is pivotally coupled to the clip to create another hinge feature. A distal end of the flap arm includes a skirt that is received by the clip seal an interior space of the spring body.
FILED Wednesday, January 19, 2022
APPL NO 17/578717
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 9/02 (20130101)
F01D 11/005 (20130101) Original (OR) Class
F01D 25/246 (20130101)

Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/28 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/60 (20130101)
F05D 2240/57 (20130101)
F05D 2300/6033 (20130101)

Pistons; Cylinders; Sealings
F16J 15/0887 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, May 23, 2023.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230523.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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