FedInvent™ Patents
Patent Details for Tuesday, June 06, 2023
This page was updated on Monday, June 19, 2023 at 06:33 PM GMT
Department of Health and Human Services (HHS)
| US 11666219 | Fox |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Michael D. Fox (Brookline, Massachusetts) |
| ABSTRACT | Methods and apparatus for providing a functional mapping of a brain lesion in a patient's brain. The method comprises determining using a computer processor, based on human connectome data stored on at least one computer datastore in communication with the computer processor, at least one functional network associated with a location of a brain lesion identified in an image of a patient's brain. The at least one functional network includes a plurality of brain areas functionally connected to the location of the brain lesion and a plurality of correlation measures. Each of the correlation measures indicates a strength of functional connection between the location of the brain lesion and a respective brain area of the plurality of brain areas in the at least one functional network. The method further comprises determining, based at least one functional network, a likelihood that the brain lesion is causing one or more patient symptoms. |
| FILED | Friday, July 28, 2017 |
| APPL NO | 16/321688 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) Original (OR) Class A61B 5/4064 (20130101) A61B 5/7425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666238 | Rege et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vasoptic Medical, Inc. (Baltimore, Maryland) |
| ASSIGNEE(S) | Vasoptic Medical Inc. (Baltimore, Maryland) |
| INVENTOR(S) | Abhishek Rege (Baltimore, Maryland); M. Jason Brooke (University Park, Maryland); Kartikeya Murari (Calgary, Canada); Yusi Liu (Rockville, Maryland) |
| ABSTRACT | Examination of the structure and function of blood vessels is an important means of monitoring the health of a subject. Such examination can be important for disease diagnoses, monitoring specific physiologies over the short- or long-term, and scientific research. This disclosure describes technology and various embodiments of a system and method for imaging blood vessels and the intra-vessel blood flow, using at least laser speckle contrast imaging, with high speed so as to provide a rapid estimate of vessel-related or blood flow-related parameters. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/333568 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) A61B 3/14 (20130101) A61B 3/0075 (20130101) A61B 3/0083 (20130101) A61B 3/1208 (20130101) A61B 3/1233 (20130101) A61B 5/02 (20130101) A61B 5/0066 (20130101) A61B 5/0261 (20130101) Original (OR) Class A61B 5/721 (20130101) A61B 5/742 (20130101) A61B 5/7207 (20130101) Optical Elements, Systems, or Apparatus G02B 27/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666263 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Cheng Yang (Charlottesville, Virginia); B. Jill Venton (Charlottesville, Virginia); Elefterios Trikantzopoulos (Richmond, Virginia) |
| ABSTRACT | A method for preparing microsensors (e.g., microelectrodes) suitable for use in electrophysiology and electrochemistry studies in vitro and in vivo is described. The method can involve preparing a polymeric resin-insulated electron conducting fiber using a 3D printed mold comprising one or more channels, wherein each of the channels includes a tapered section. An electron conducting fiber partially enclosed within a metal or glass support can be laid in a channel; and a polymeric resin can be poured into the channel and cured, providing a polymer-insulated electron conducting fiber having a tapered section in proximity to a polymer-free electroactive tip area. For example, the method can be used to provide a polyimide-insulated carbon fiber microsensor. The mold can be used for the batch fabrication of the microsensors. The microsensors themselves, the molds for making the microsensors, and methods of using the microsensors are also described. |
| FILED | Wednesday, August 16, 2017 |
| APPL NO | 16/314492 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/283 (20210101) Original (OR) Class A61B 5/291 (20210101) A61B 2562/028 (20130101) A61B 2562/125 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 1/04 (20130101) H01B 1/24 (20130101) H01B 3/306 (20130101) H01B 3/307 (20130101) H01B 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666385 | Feiner et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (, None) |
| INVENTOR(S) | Steven Feiner (New York, New York); Gabrielle Loeb (Wynnewood, Pennsylvania); Alon Grinshpoon (New York, New York); Shirin Sadri (San Clemente, California); Carmine Elvezio (Bellmore, New York) |
| ABSTRACT | Certain embodiments include a method for assisting a clinician in performing a medical procedure on a patient using augmented reality guidance. The method can include obtaining a three-dimensional model of an anatomic part of the patient. The method can also include aligning the three-dimensional model with data to form augmented reality guidance for the medical procedure. In addition, the method can include presenting the augmented reality guidance to the clinician during the medical procedure using an augmented reality three-dimensional display. |
| FILED | Thursday, February 20, 2020 |
| APPL NO | 16/796645 |
| ART UNIT | 2173 — Graphical User Interface and Document Processing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 2034/107 (20160201) A61B 2034/108 (20160201) Electric Digital Data Processing G06F 3/167 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 19/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666444 | Kheradvar et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Arash Kheradvar (Irvine, California); Gregory S. Kelley (Santee, California) |
| ABSTRACT | Described is a collapsible atrial cage for percutaneous delivery and implantation of an atrioventricular valve within an atrium of the heart. The atrial cage includes an atrial portion and a ventricular portion. The ventricular portion is attached with and separated from the atrial portion by a valve juncture portion. Notably, the cage includes at least one interlock shaped to lock with and secure an atrioventricular valve proximate the valve juncture portion. Thus, when deployed and expanded, the atrioventricular valve is secured at the atrioventricular juncture. |
| FILED | Thursday, August 02, 2018 |
| APPL NO | 16/636170 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2415 (20130101) A61F 2/2418 (20130101) A61F 2/2487 (20130101) Original (OR) Class A61F 2210/0014 (20130101) A61F 2220/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666445 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Yunzhi Yang (Stanford, California); Stuart B. Goodman (Los Altos, California); Yaser Shanjani (Milpitas, California); Chi-Chun Pan (Stanford, California) |
| ABSTRACT | An engineered medical device for treatment of osteonecrosis is provided where the size, porosity and ceramic content of the device can be personalized based on an individual patient's anatomical and physiological condition. The device distinguishes different segments mimicking anatomically-relevant cortical and cancellous segments, in which the cortical segments of the device can sustain mechanical loading, and the cancellous segment of the device can promote bone ingrowth, osteogenesis and angiogenesis. |
| FILED | Wednesday, June 17, 2020 |
| APPL NO | 16/904408 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/28 (20130101) Original (OR) Class A61F 2002/2828 (20130101) A61F 2002/2835 (20130101) A61F 2310/00179 (20130101) A61F 2310/00796 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666539 | Xu |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Boston, Massachusetts) |
| INVENTOR(S) | Qiaobing Xu (Lexington, Massachusetts) |
| ABSTRACT | Disclosed are (i) compounds of formula I, or pharmaceutically acceptable salts thereof, and (ii) lipidoid nanoparticles comprising compound of formula I or pharmaceutically acceptable salts thereof, as well as their use as vehicles for drug delivery across the blood-brain barrier. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/339563 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) Original (OR) Class A61K 38/45 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 215/20 (20130101) C07C 323/58 (20130101) Heterocyclic Compounds C07D 209/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666547 | Martina et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Marco Martina (Evanston, Illinois); Herbert Y. Meltzer (Evanston, Illinois) |
| ABSTRACT | Disclosed are methods for treating a psychiatric disease or disorder and/or symptoms thereof in a subject in need thereof, the method comprising administering to the subject an effective amount of an antagonist of the Na+-K+-2Cl— cation-chloride cotransporter isoform 1 (NKCC1) for treating the psychiatric disorder and/or the symptoms thereof in the subject. The methods further may include administering to the subject a dopamine D1 agonist and/or a GABAA agonist, optionally at a subeffective dose, where co-administering the antagonist of NKCC1 improves the efficacy of the dopamine D1 agonist and/or the GABAA agonist, optionally at the subeffective dose, for treating the psychiatric disease or disorder and/or symptoms thereof. |
| FILED | Monday, June 29, 2020 |
| APPL NO | 16/915746 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/57 (20130101) A61K 31/196 (20130101) Original (OR) Class A61K 31/4365 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/18 (20180101) A61P 25/24 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666569 | Gradilone et al. |
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| FUNDED BY |
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| APPLICANT(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
| ASSIGNEE(S) | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS) U.S. GOVERNMENT (Bethesda, Maryland) |
| INVENTOR(S) | Sergio A. Gradilone (Rochester, Minnesota); Nicholas F. LaRusso (Rochester, Minnesota) |
| ABSTRACT | An HDAC6-specific inhibitor (i.e., a compound of Formula I or II) is shown to reduce the pathogenesis associated with polycystic disease. Administration of an HDAC6-specific inhibitor attenuated many of the symptoms characteristic of polycystic liver disease including cyst formation, cyst growth and cholangiocyte proliferation. Treatment with a HDAC6-specific inhibitor also increased the amount of bile duct acetylated tubulin and β-catenin phosphorylation and/or acetylation while reducing bile duct β-catenin synthesis. These results demonstrate that HDAC6 is overexpressed in cystic cholangiocytes and that its pharmacological inhibition reduces cholangiocyte proliferation and cyst growth. |
| FILED | Thursday, May 14, 2020 |
| APPL NO | 16/874251 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666578 | Roush et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainseville, Florida); THE UNIVERSITY OF FLORIDA BOARD OF TRUSTEES (Gainesville, Florida) |
| INVENTOR(S) | William R. Roush (Jupiter, Florida); Derek R. Duckett (Jupiter, Florida); Andrii Monastyrskyi (Jupiter, Florida) |
| ABSTRACT | The invention provides compounds and methods of inhibiting a cyclin-dependent kinase, comprising contacting the cyclin-dependent kinase and an effective amount or concentration of a compound of formula (I) wherein variables are as defined herein. Compounds of formula (I) can be highly selective inhibitors of cyclin-dependent kinases such as CDK12/13, relative to other kinases such as casein kinases, such as CK1δ/ε. Compounds can be used in treatment of cancers, such as breast cancer, brain cancer and ovarian cancer. |
| FILED | Tuesday, May 07, 2019 |
| APPL NO | 17/053652 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5377 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666580 | Polyak et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kornelia Polyak (Brookline, Massachusetts); Shaokun Shu (Brookline, Massachusetts); James E. Bradner (Weston, Massachusetts); Charles Yang Lin (Houston, Texas) |
| ABSTRACT | The present disclosure provides combination therapy comprising a BET inhibitor and a protein phosphatase 2A (PP2A) activator, a B-cell lymphoma-2 (Bcl-2) inhibitor, a B-cell lymphoma-extra large (Bcl-xl) inhibitor, a casein kinase 2 (CK2) inhibitor, and/or a mediator complex subunit 1 (MED1) for cancer. The combination therapy is expected to be synergistic in treating the cancer, compared to the monotherapy. Methods for identifying a subject having a cancer that is resistant to or at risk of developing resistance to bromodomain and extra terminal (BET) inhibitor therapy are also provided. |
| FILED | Wednesday, August 10, 2016 |
| APPL NO | 15/751914 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/137 (20130101) A61K 31/551 (20130101) Original (OR) Class A61K 31/551 (20130101) A61K 31/635 (20130101) A61K 31/5415 (20130101) A61K 31/5415 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666589 | Lothstein et al. |
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| FUNDED BY |
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| APPLICANT(S) | Paradox Pharmaceuticals, Inc. (Memphis, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leonard Lothstein (Eads, Tennessee); Judith Soberman (Eads, Tennessee); Tiffany N. Seagroves (Memphis, Tennessee) |
| ABSTRACT | The present invention relates to compositions comprising at least one of pivarubicin and benzarubicin, or a pharmaceutically acceptable salt thereof, and methods for using the compositions in the treatment of triple negative breast cancer (TNBC) by administering an effective amount of the compositions to a subject. In some instances, the subject is a mammal, including at least one of human, feline, and canine mammals. |
| FILED | Tuesday, March 02, 2021 |
| APPL NO | 17/190317 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) Original (OR) Class A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/14 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666592 | Hirano et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Michio Hirano (New York, New York); Caterina Garone (Cambridge, United Kingdom); Ramon Marti (Barcelona, Spain) |
| ABSTRACT | The invention relates generally to a pharmacological therapy for human genetic diseases, specifically those characterized by unbalance nucleotide pools, more specifically mitochondrial DNA depletion syndromes, and more specifically, thymidine kinase 2 (TK2) deficiency. The pharmacological therapy involves the administration of at least one deoxynucleoside, or mixtures thereof. For the treatment of TK2 deficiency, the pharmacological therapy involves the administration of either deoxythymidine (dT) or deoxycytidine (dC), or mixtures thereof. This administration of deoxynucleosides is applicable to other disorders of unbalanced nucleotide pools, especially those found in mitochondrial DNA depletion syndrome. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/242822 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/513 (20130101) A61K 31/513 (20130101) A61K 31/708 (20130101) A61K 31/708 (20130101) A61K 31/7068 (20130101) A61K 31/7068 (20130101) A61K 31/7072 (20130101) Original (OR) Class A61K 31/7072 (20130101) A61K 31/7076 (20130101) A61K 31/7076 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666611 | Bry et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Lynn Bry (Jamaica Plain, Massachusetts); Georg Gerber (Newton, Massachusetts); Jessica Allegretti (Boston, Massachusetts); Richard Lavin (Brighton, Massachusetts); Nicholas DiBenedetto (Meford, Massachusetts) |
| ABSTRACT | Described herein are methods and compositions for the use of treating and/or preventing Clostridium difficile infections, including recurrent C. difficile infections, in a subject. Aspects of the technology relate to administering to a subject in need thereof a composition comprising a defined therapeutic microbiota comprising, e.g. Clostridial species. Also described herein are biomarker profiles, including a biomarker profile comprising two groups of Clostridial species, that is predictive of the likelihood of recurrent C. difficile infection and/or susceptibility to initial C. difficile infection. |
| FILED | Tuesday, December 11, 2018 |
| APPL NO | 16/771979 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0031 (20130101) A61K 9/0053 (20130101) A61K 35/741 (20130101) A61K 35/742 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/34 (20130101) A61K 47/42 (20130101) A61K 47/183 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/06 (20130101) C12Q 1/26 (20130101) C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/50 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666630 | George et al. |
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| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia); RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY (Thiruvananthapuram, India) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Rajiv Gandhi Centre for Biotechnology (Thiruvananthapuram, India) |
| INVENTOR(S) | Sanil George (Thimvananthapuram, India); Joshy Jacob (Snellville, Georgia); David Holthausen (Atlanta, Georgia); Song Hee Lee (Atlanta, Georgia); Jessica Shartouny (Atlanta, Georgia) |
| ABSTRACT | Antiviral polypeptides and methods of use are provided herein. In particular, these polypeptides can comprise the Yodha amino acid sequence, variants, derivatives, or truncated versions thereof. In certain embodiments, this disclosure relates to uses of the peptides, nucleic acid molecules, and compositions disclosed herein to treat or prevent a viral infection. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/127161 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/17 (20130101) Original (OR) Class A61K 38/46 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 14/463 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666633 | Hsu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Sheau Yu Hsu (Menlo Park, California); Chia Lin Chang (Palo Alto, California) |
| ABSTRACT | Long-acting agonistic analogs for CLR/RAMP receptors are provided that have an extended half-live in vivo. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/043642 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/22 (20130101) Original (OR) Class A61K 47/50 (20170801) Peptides C07K 14/575 (20130101) C07K 16/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666636 | Niswender et al. |
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| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Kevin Niswender (Nashville, Tennessee); Stokes Peebles (Nashville, Tennessee) |
| ABSTRACT | The present disclosure relates to glucagon-like peptide-1 receptor (GLP-1R) agonists and methods of treating or preventing allergic inflammation and/or methods of treating or preventing respiratory syncytial virus (RSV) infection. |
| FILED | Wednesday, February 14, 2018 |
| APPL NO | 16/485190 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/26 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666640 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Gong Chen (State College, Pennsylvania); Zheng Wu (State College, Pennsylvania) |
| ABSTRACT | Neonatal seizure is different from adult seizure, and many anti epileptic drugs that are effective in adults often fail to treat neonatal seizure. Gluconic acid, a natural organic acid enriched in fruits and honey, and the glucose oxidase enzyme, is shown herein to potently inhibit neonatal epilepsy both in vitro and in vivo. Sodium gluconate is shown to inhibit epileptiform burst activity in cell cultures and protect neurons from kainic acid-induced cell death. Sodium gluconate also inhibited epileptiform burst activity in brain slices in a manner that was much more potent in neonatal animals than in older animals. Consistently, in vivo EEC recordings also revealed that sodium gluconate inhibited the epileptic seizure activity in a manner that was much more potent in neonates than in adult animals. Mechanistically, sodium gluconate inhibits voltage-dependent CLC-3 C1− channels both in neuronal cultures and in hippocampal slices. Together, these data suggest a novel antiepileptic drug gluconate that potently inhibits neonatal seizures through blocking CLC-3 C1− channels. |
| FILED | Thursday, January 03, 2019 |
| APPL NO | 16/957087 |
| ART UNIT | 1699 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/443 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) Enzymes C12Y 101/03004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666647 | Hazlett et al. |
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| FUNDED BY |
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| APPLICANT(S) | ALBANY MEDICAL COLLEGE (Albany, New York) |
| ASSIGNEE(S) | ALBANY MEDICAL COLLEGE (Albany, New York) |
| INVENTOR(S) | Karsten Hazlett (East Berne, New York); Kristen M. Tummillo (Union, New Jersey); Edmund J. Gosselin (Delanson, New York) |
| ABSTRACT | An approach for modifying multiple types of bacteria to produce surface modifications that enhance the immunologic response when used as a vaccine. A series of plasmids (pYF, pYFC, pYFP, pSF, pSPF, and pSCF) may be used to transform bacteria which then produce surface-exposed ligands that bind to complement receptors on antigen presenting cells. When modified bacteria are used as a vaccine, the vaccine recipients produce significantly higher titers of specific antibodies and are better protected against challenges from the disease-causing bacteria. |
| FILED | Tuesday, September 29, 2020 |
| APPL NO | 17/036526 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) A61K 38/1725 (20130101) A61K 39/02 (20130101) Original (OR) Class A61K 2039/55516 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 2310/3517 (20130101) C12N 2800/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666648 | Jacobs, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
| INVENTOR(S) | William R. Jacobs, Jr. (Pelham, New York); Sangeeta Tiwari (Bronx, New York) |
| ABSTRACT | Provided are attenuated strains of M. tuberculosis and M. bovis BCG which are double auxotrophic mutants with genes knocked out in the biosynthetic pathways for arginine and methionine, and compositions and methods of use thereof. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 17/268789 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) Original (OR) Class A61K 2039/522 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666661 | Nomura et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); FRONTIER MEDICINES CORPORATION (Portola Valley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Frontier Medicines Corporation (Portola Valley, California) |
| INVENTOR(S) | Daniel K. Nomura (Walnut Creek, California); Roberto Zoncu (San Francisco, California); Carl Ward (Berkeley, California); Sin Ki Fung (Berkeley, California); Chris Kumar Varma (Portola Valley, California); Benjamin Fontaine (Berkeley, California) |
| ABSTRACT | Provided herein, inter alia, are methods and compounds for targeted autophagy. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/362573 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/6803 (20170801) A61K 47/6889 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 25/14 (20180101) A61P 25/28 (20180101) A61P 35/00 (20180101) A61P 37/06 (20180101) Heterocyclic Compounds C07D 417/12 (20130101) C07D 495/04 (20130101) Peptides C07K 16/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666663 | Shapiro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bruce A. Shapiro (Gaithersburg, Maryland); Paul J. Zakrevsky (Frederick, Maryland); Luc Jaeger (Goleta, California) |
| ABSTRACT | Disclosed are nanostructures comprising a ribonucleic acid (RNA) scaffold comprising a hexameric tetrahedral core. The tetrahedral core may comprise four hexameric RNA nanorings linked together. Related pharmaceutical compositions, methods of modulating the expression of a target gene in a mammal, methods of treating or preventing a disease in a mammal, and methods of producing a hexameric tetrahedral RNA nanostructure are also disclosed. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 17/053615 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/549 (20170801) A61K 47/6929 (20170801) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666665 | Wagers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Amy J. Wagers (Cambridge, Massachusetts); Mohammadsharif Tabebordbar (Cambridge, Massachusetts); Wei Leong Chew (Boston, Massachusetts); George M. Church (Brookline, Massachusetts) |
| ABSTRACT | Methods of editing target nucleic acids are provided using a guide RNA and a Cas9 protein to excise exons in a target gene and where the edited gene is expressed to produce a truncated polypeptide. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 16/834339 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666666 | Pyle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | April D. Pyle (Los Angeles, California); Courtney S. Young (Los Angeles, California); Melissa J. Spencer (Los Angeles, California) |
| ABSTRACT | The present disclosure provides a method of modifying a mutant dystrophin gene in the genome of a cell. The present disclosure further provides compositions and kits for modifying a mutant dystrophin gene in the genome of a cell. |
| FILED | Thursday, February 09, 2017 |
| APPL NO | 16/076616 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0306 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) Original (OR) Class A61K 48/0091 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Peptides C07K 14/4708 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) C12N 15/113 (20130101) C12N 15/861 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666672 | Hui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Susanta Kumar Hui (Duarte, California); Paul J. Yazaki (Duarte, California); Srideshikan Sargur Madabushi (Duarte, California) |
| ABSTRACT | Disclosed is a non-invasive PET-CT imaging method for detecting acute myeloid leukemia (AML) or extramedullary disease (EMD) in a subject using a radioactive isotope-labeled anti-CD33 antibody. Also disclosed is a PET-CT imaged-guided method for treating AML or EMD. |
| FILED | Thursday, November 21, 2019 |
| APPL NO | 16/691071 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/5235 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 51/1045 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1039 (20130101) A61N 2005/1052 (20130101) Peptides C07K 16/2803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666686 | Wynne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WYNNVISION, LLC (Richmond, Virginia) |
| ASSIGNEE(S) | WynnVision, LLC (Richmond, Virginia) |
| INVENTOR(S) | Kenneth J. Wynne (Midlothian, Virginia); Olga Zolotarskaya (Richmond, Virginia); Rebecca Jarrell (Williamsburg, Virginia); Kennard Brunson (Richmond, Virginia); Chenyu Wang (Midlothian, Virginia) |
| ABSTRACT | A composition, comprising: a physiologically-acceptable polydimethylsiloxane having a surface; and one or more normal C6-C20NR1R2 saturated amine, salt thereof, or combination thereof, in contact with the polydimethylsiloxane, the surface, or both, wherein R1 and R2 may be same or different and independently selected from H, —CH3, —CH2CH3, —CH2CH2CH3, or combination thereof. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/867252 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) A01N 33/04 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/06 (20130101) Original (OR) Class A61L 29/06 (20130101) A61L 29/08 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/06 (20130101) A61L 2300/204 (20130101) A61L 2300/404 (20130101) A61L 2420/02 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667598 | Serhan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Charles N. Serhan (Needham, Massachusetts); Jesmond Dalli (London, United Kingdom) |
| ABSTRACT | The invention describes novel mono-hydroxy, di-hydroxy and tri-hydroxy docosapentaenoic acid (DPA) analogues, their preparation, isolation, identification, purification and uses thereof. |
| FILED | Monday, August 26, 2019 |
| APPL NO | 16/551697 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 57/03 (20130101) Original (OR) Class Heterocyclic Compounds C07D 303/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667623 | Watts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Val J. Watts (West Lafayette, Indiana); Richard M. van Rijn (West Lafayette, Indiana); Daniel Patrick Flaherty (West Lafayette, Indiana); Jatinder Kaur (West Lafayette, Indiana) |
| ABSTRACT | The present invention relates to a method of treatment for chronic pain, opioid dependence, alcohol use disorder or autism using a class of pyrimidinone compounds, an adenylyl cyclase 1 (AC1) inhibitor. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases in mammals using those compounds disclosed herein. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839219 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/32 (20180101) A61P 25/36 (20180101) Heterocyclic Compounds C07D 403/04 (20130101) Original (OR) Class C07D 405/14 (20130101) C07D 409/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667658 | Rosen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Barry P. Rosen (Boynton Beach, Florida); Masafumi Yoshinaga (Doral, Florida); Stanislaw F. Wnuk (Miami, Florida); Md Abu Hasan Howlader (Miami, Florida); Sk Md Sazzad Hossain Suzol (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Barry P. Rosen (Boynton Beach, Florida); Masafumi Yoshinaga (Doral, Florida); Stanislaw F. Wnuk (Miami, Florida); Md Abu Hasan Howlader (Miami, Florida); Sk Md Sazzad Hossain Suzol (Philadelphia, Pennsylvania) |
| ABSTRACT | The subject invention provides methods for the chemical synthesis of racemic arsinothricin (D,L-AST), the novel organoarsenical antibiotic. One is by condensation of the 2-chloroethyl(methyl)arsinic acid with acetamidomalonate, and the second involves reduction of the N-acetyl-protected derivative of hydroxyarsinothricin (AST-OH) and subsequent methylation of the resulting sodium salt of trivalent arsenic intermediate with methyl iodide. The enzyme AST N-acetyltransferase (ArsN1) was utilized to purify L-AST from racemic AST. This expedient chemical synthesis of AST provides a source of this novel antibiotic for future drug development. |
| FILED | Monday, December 05, 2022 |
| APPL NO | 18/074835 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/72 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667676 | Chong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Lucy S. Chong (Pasadena, California); Ronghui Zhu (Pasadena, California); Xiaofei Ge (Beijing, China PRC); Michael B. Elowitz (Pasadena, California); Mark W. Budde (Arcadia, California) |
| ABSTRACT | Disclosed herein include methods, compositions, and kits suitable for use in thresholding of protein signals. There are provided, in some embodiments, synthetic protein circuits that respond to inputs only above or below a certain threshold concentration. In some embodiments, the threshold value itself is tunable. Methods of treating a disease or disorder characterized by aberrant signaling are provided in some embodiments. |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 16/738664 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/001 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667677 | Tak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Y. Esther Tak (Charlestown, Massachusetts); Benjamin Kleinstiver (Medford, Massachusetts); J. Keith Joung (Winchester, Massachusetts) |
| ABSTRACT | Drug-inducible, tunable, and multiplexable Clustered Regularly Interspaced Short Palindromic Repeats from Prevotella and Francisella 1 (Cpf1)-based activators, and methods of use thereof. |
| FILED | Monday, April 23, 2018 |
| APPL NO | 16/606680 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/52 (20130101) C12N 15/62 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2310/153 (20130101) C12N 2710/16222 (20130101) C12N 2800/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667678 | Pahan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rush University Medical Center (Chicago, Illinois) |
| ASSIGNEE(S) | Rush University Medical Center (Chicago, Illinois) |
| INVENTOR(S) | Kalipada Pahan (Skokie, Illinois) |
| ABSTRACT | Compositions for inhibiting the binding between ACE2 and SARS-CoV-2 spike S1 are disclosed. Methods of treating COVID-19 are disclosed. Methods of making an in vivo model of COVID-19 are also disclosed. |
| FILED | Monday, March 21, 2022 |
| APPL NO | 17/699792 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/162 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/20022 (20130101) C12N 2770/20033 (20130101) C12N 2770/20071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667690 | Palmenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Ann Carol Palmenberg (Madison, Wisconsin); Kelly Watters (Madison, Wisconsin) |
| ABSTRACT | The present invention provides soluble truncated peptides of CDHR3, recombinant variants thereof and methods of making these peptides. The present invention also provide methods of inhibiting rhinovirus C infection and an in vitro assay for screening for anti-viral agents against rhinovirus C. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 17/058934 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667692 | Tran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Eric Tran (Portland, Oregon); Yong-Chen Lu (Rockville, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/739310 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/82 (20130101) C07K 14/7051 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) G01N 2333/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667695 | Refaeli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TAIGA BIOTECHNOLOGIES, INC. (Aurora, Colorado) |
| ASSIGNEE(S) | Taiga Biotechnologies, Inc. (Aurora, Colorado) |
| INVENTOR(S) | Yosef Refaeli (Denver, Colorado); Brian Turner (Denver, Colorado) |
| ABSTRACT | Provided herein are various processes for the improved production of antibody producing organisms, antibody producing tissues, antibody producing cells and antibodies. In certain embodiments, provided herein are methods for rapidly producing antibody producing organisms, tissues, cells and antibodies derived from humans, organisms, plants or cells that are genetically altered to over-express certain proteins. |
| FILED | Thursday, October 10, 2019 |
| APPL NO | 16/598690 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 2039/53 (20130101) A61K 2039/505 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/82 (20130101) Original (OR) Class C07K 16/00 (20130101) C07K 16/40 (20130101) C07K 16/1018 (20130101) C07K 2319/10 (20130101) C07K 2319/20 (20130101) C07K 2319/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667697 | Crowe, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | James E. Crowe, Jr. (Nashville, Tennessee); Iuliia Gilchuk (Nashville, Tennessee) |
| ABSTRACT | The present disclosure is directed to antibodies binding to and neutralizing Poxvirus and methods for use thereof. |
| FILED | Wednesday, October 18, 2017 |
| APPL NO | 16/343107 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) Peptides C07K 16/081 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667725 | Elias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Jack A. Elias (Providence, Rhode Island); Chun Geun Lee (Woodbridge, Connecticut); Chuan Hua He (Madison, Connecticut); Bing Ma (Branford, Connecticut); Suchitra Kamle (Providence, Rhode Island); Chang-Min Lee (Warwick, Rhode Island) |
| ABSTRACT | Described herein are methods and compositions relating to anti-Chi3L1 antibodies, antibody reagents, and antigen-binding fragments thereof which display superior properties, e.g., high sensitivity, high specificity, high binding affinity, neutralization activity ex vivo and in vivo (e.g., blocks Chi3L1-induced MAPK and AKT signaling). Methods of treatment, e.g., of treating cancer, obesity, and/or asthma by administering the compounds described herein are also provided. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/939265 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 19/02 (20180101) A61P 29/00 (20180101) A61P 31/04 (20180101) A61P 35/00 (20180101) A61P 35/04 (20180101) Peptides C07K 16/18 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667726 | Elias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Jack A. Elias (Providence, Rhode Island); Chun Geun Lee (Woodbridge, Connecticut); Chuan Hua He (Madison, Connecticut); Bing Ma (Branford, Connecticut); Suchitra Kamle (Providence, Rhode Island); Chang-Min Lee (Warwick, Rhode Island) |
| ABSTRACT | It is demonstrated herein that inhibitors of immune checkpoints and CHI3L1 are synergistic. Accordingly, described herein are methods and compositions relating to combinatorial therapies for cancer, e.g., comprising an inhibitor of CHI3L1; and an inhibitor of an immune checkpoint protein. In some embodiments, the CHI3L1 inhibitor can be an antibody or antibody reagent as described herein. |
| FILED | Thursday, July 30, 2020 |
| APPL NO | 16/943320 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Peptides C07K 16/40 (20130101) Original (OR) Class C07K 16/2803 (20130101) C07K 16/2839 (20130101) C07K 2317/34 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667899 | Pyle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Anna Marie Pyle (Guilford, Connecticut); Chen Zhao (New Haven, Connecticut) |
| ABSTRACT | The present invention provides compositions, methods, and kits related to reverse transcriptases derived from E.r. maturase. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/626008 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1276 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Enzymes C12Y 207/07049 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667900 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yingxiao Wang (San Diego, California); Shu Chien (La Jolla, California); Lei Lei (San Diego, California); Shaoying Lu (San Diego, California); Jie Sun (San Diego, California) |
| ABSTRACT | Provided are Shp2- and Spleen tyrosine kinase (Syk)-integrated sensing and actuating protein (iSNAP) (Shp2- and Syk-iSNAP) chimeric proteins comprising: a bi-phosphorylatable peptide, optionally a bisphosphoryl tyrosine-based activation (BTAM) motif; a Fluorescent Protein (FP) Förster Resonance Energy Transfer (FRET) (or FP FRET) pair or pair of motifs; a truncated Shp2 domain comprising an N-Src Homology 2(N-SH2) domain and a C-Src Homology 2(C-SH2) domain; and, a phosphatase (PTP) domain or a kinase domain. Provided are engineered cells and methods for cancer cell or tumor eradication, or for the treatment or amelioration of a cancer, tumor or dysfunctional cell, or for promoting an anti-cancer, anti-tumor or anti-dysfunctional cell inflammatory response, including enhancing macrophage-, monocyte-, microglia-, osteoclast-, Kupffer cell- or dendritic cell-mediated antibody- or monoclonal antibody (mAb)-guided cancer or dysfunctional cell or tumor eradication, amelioration, or treatment. |
| FILED | Thursday, July 12, 2018 |
| APPL NO | 16/631041 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/39558 (20130101) Peptides C07K 14/435 (20130101) C07K 2319/03 (20130101) C07K 2319/61 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/03048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667903 | Yeo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (La Jolla, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eugene Yeo (La Jolla, California); David A. Nelles (La Jolla, California); Mark Fang (La Jolla, California); Ranjan Batra (La Jolla, California) |
| ABSTRACT | Cas9 polypeptides which target RNA and method of using them are provided. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 16/794918 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/0058 (20130101) Peptides C07K 2319/09 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/10 (20130101) C12N 2310/20 (20170501) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667919 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Da Yang (Pittsburgh, Pennsylvania); Zehua Wang (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods of treating cancer are provided along with nucleic acids and nucleic acid analog sequences of a long-non-coding RNA (lncRNA), and reagents useful for knocking down the lncRNA. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/970845 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/551 (20130101) A61K 31/5517 (20130101) A61K 31/7088 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2320/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667920 | Liu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Da Zhi Liu (Davis, California) |
| ABSTRACT | The disclosure provides methods and pharmaceutical compositions that include a microRNA (miR) or a mimic thereof and a pharmaceutically acceptable carrier for treating brain injuries (e.g., traumatic brain injury (TBI)), preventing or reducing neuronal death, preventing or reducing leukocyte infiltration, and/or preventing or reducing blood-brain barrier (BBB) disruption after brain injuries (e.g., TBI) in a subject. The miR may be selected from the group consisting of miR-125b-5p, miR-122-5p, and a combination thereof. In some embodiments, the methods include administering to the subject the miR or the mimic thereof to decrease the expression level of one or more genes (e.g., Mknk2, Alpk3, and Neu1). |
| FILED | Tuesday, August 18, 2020 |
| APPL NO | 16/996616 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667949 | Korennykh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Alexei Korennykh (Princeton, New Jersey); Alisha Chitrakar (Princeton, New Jersey); Jesse Donovan (Princeton, New Jersey) |
| ABSTRACT | The present disclosure relates, in general, to a fusion protein construct comprising RNase L and a split reporter system, and methods of using the reporter for detecting 2′-5′ linked oligoadenylates (2-5A) and double stranded RNA in vivo. |
| FILED | Friday, February 15, 2019 |
| APPL NO | 16/277632 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 2319/61 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/0069 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) Original (OR) Class C12Q 1/66 (20130101) Enzymes C12Y 113/12007 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/02 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667960 | Worobey et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Michael Worobey (Tucson, Arizona); Thomas Watts (Tucson, Arizona) |
| ABSTRACT | Disclosed are methods and systems for detecting RNA and sequencing RNA in a wide range of samples such as samples with low concentrations of nucleic acid, samples with degraded nucleic acid, samples that would not otherwise be amenable to conventional sequencing or RNA detection methods, poor quality samples, high quality samples in which rare mutations are sought, formalin-fixed paraffin-embedded samples, blood samples, etc. The methods of the present invention may use paired, large panels of primers to amplify many short fragments that overlap between but not within each panel. Each panel's amplicon set may fill the gaps between those of the opposing panel, thereby providing complete gene or genomic coverage. A preliminary, multiplex amplification step amplifies target nucleic acid for all downstream reactions such as Sanger sequencing, cloning, and Next Generation Sequencing (NGS). |
| FILED | Thursday, April 20, 2017 |
| APPL NO | 16/089658 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) C12Q 1/70 (20130101) C12Q 1/703 (20130101) C12Q 1/6844 (20130101) Original (OR) Class C12Q 1/6844 (20130101) C12Q 2521/107 (20130101) C12Q 2521/107 (20130101) C12Q 2525/204 (20130101) C12Q 2525/204 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667970 | Bashir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Rashid Bashir (Champaign, Illinois); Anurup Ganguli (Champaign, Illinois); Farhad Kosari (Rochester, Minnesota) |
| ABSTRACT | Various methods and devices for spatial molecular analysis from tissue is provided. For example, a method of spatially mapping a tissue sample is provided with a microarray having a plurality of wells, wherein adjacent wells are separated by a shearing surface; overlaying said microarray with a tissue sample; applying a deformable substrate to an upper surface of said tissue sample; applying a force to the deformable substrate, thereby forcing underlying tissue sample into the plurality of wells; shearing the tissue sample along the shearing surface into a plurality of tissue sample islands, with each unique tissue sample island positioned in a unique well; and imaging or quantifying said plurality of tissue sample islands, thereby generating a spatial map of said tissue sample. The imaging and/or quantifying may use a nucleic acid amplification technique. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/939665 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/5085 (20130101) B01L 3/50851 (20130101) B01L 2200/0642 (20130101) B01L 2300/0819 (20130101) B01L 2300/0858 (20130101) B01L 2300/0893 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1003 (20130101) C12N 15/1003 (20130101) C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6827 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2521/107 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) G01N 2001/282 (20130101) G01N 2001/2873 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 25/10 (20190201) G16B 30/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667972 | Salk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/392180 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667976 | Vogelstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Luis Diaz (Ellicott City, Maryland); Nickolas Papadopoulos (Towson, Maryland); George J. Netto (Baltimore, Maryland); Ralph Hruban (Baltimore, Maryland); Isaac A. Kinde (Beaumont, California) |
| ABSTRACT | TERT promoter mutations occur in both papillary and flat lesion bladder cancers, are the most frequent genetic alterations identified to date in noninvasive precursor lesions of the bladder, are detectable in urine, and appear to be strongly associated with bladder cancer recurrence. The TERT promoter mutations are useful urinary biomarker for both the early detection and monitoring of bladder neoplasia. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097510 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668556 | Fujimoto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | James G. Fujimoto (Medford, Massachusetts); Eric Michael Moult (Cambridge, Massachusetts); ByungKun Lee (Cambridge, Massachusetts) |
| ABSTRACT | A computer-implemented method of imaging an object, and an optical coherent tomography (OCT) imaging system implementing same. The method comprises acquiring a three-dimensional optical coherence tomography (OCT) data set representing an object, wherein the OCT data set includes at least a first and a second three-dimensional data subsets, each element of the OCT data set having a respective sampling period, wherein at least a first element of the first data subset represents a point in space that is not represented by any element of the second subset, and at least one element of the second subset has a sampling period different from the sampling period of the first element of the first subset; processing at least the first and the second data subsets according to at least one imaging modality, thereby generating at least a first and a second processed data subsets, each processed data subset representing the object; and generating a composite image representing the object based on at least the first and the second processed data subsets. |
| FILED | Friday, May 04, 2018 |
| APPL NO | 16/611011 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) A61B 3/107 (20130101) A61B 3/1233 (20130101) A61B 3/1241 (20130101) A61B 5/0035 (20130101) A61B 5/0066 (20130101) A61B 5/0261 (20130101) A61B 5/0285 (20130101) A61B 5/02014 (20130101) A61B 5/7425 (20130101) A61B 5/14535 (20130101) A61B 5/14552 (20130101) A61B 90/39 (20160201) A61B 2090/3937 (20160201) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02045 (20130101) G01B 9/02091 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668631 | Kounovsky-Shafer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Kristy Leigh Kounovsky-Shafer (Kearney, Nebraska); Cody Dean Masters (Kearney, Nebraska); Jocelyn Dolphin (Blair, Nebraska); April Vonderfecht (Deshler, Nebraska) |
| ABSTRACT | This disclosure relates to mesofluidic devices and methods for eluting and concentrating a plurality of nucleic acid molecules. The mesofluidic device includes a device frame having a bottom surface upon which is defined a first reservoir and the second reservoir. The first reservoir includes a first electrode, and the second reservoir includes a second electrode. The first and second electrodes are configured for electrical connection. The mesofluidic device includes an elongated channel extending between the first reservoir and the second reservoir. The mesofluidic device includes a first slot having a first slot width. The first slot is configured to receive an insert. The first slot intersects the elongated channel. The mesofluidic device includes a second slot having a second slot width. The second slot is configured to receive a separation material having a first porosity. The second slot intersects the elongated channel. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 16/592695 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/508 (20130101) B01L 2300/12 (20130101) B01L 2300/0645 (20130101) B01L 2300/0681 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1017 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4005 (20130101) Original (OR) Class G01N 27/44747 (20130101) G01N 2001/4016 (20130101) G01N 2001/4038 (20130101) G01N 2001/4088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668638 | Sulchek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Todd Sulchek (Atlanta, Georgia); Alexander Alexeev (Atlanta, Georgia); Bushra Tasadduq (Atlanta, Georgia) |
| ABSTRACT | A microchannel for processing cells by compression of the cells including an inlet, ridges and an outlet. Each ridge including a compressive surface and a cell adhesion entity. The outlet configured to remove at least one of a first portion of the cells and a second portion of the cells from the microchannel. Each ridge oriented at an angle of from 25 degrees to 70 degrees relative to a center axis of the microchannel. The cell adhesion entity configured such that the first portion of the cells has a first adhesion property relative to the cell adhesion entity to follow a first trajectory through the microchannel. The cell adhesion entity further configured such that the second portion of the cells has a second adhesion property relative to the cell adhesion entity to follow a second trajectory through the microchannel. The first trajectory is different from the second trajectory. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/650033 |
| ART UNIT | 1677 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/16 (20130101) B01L 2300/0877 (20130101) B01L 2400/086 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 15/1056 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668641 | Lo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yu-Hwa Lo (San Diego, California); Yuanyuan Han (San Diego, California); Yi Gu (San Diego, California); Ce Zhang (La Jolla, California) |
| ABSTRACT | Disclosed are systems, devices and methods for imaging and image-based sorting of particles in a flow system, including cells in a flow cytometer. In some aspects, a system includes a particle flow device to flow particles through a channel, an imaging system to obtain image data of a particle during flow through the channel, a processing unit to determine a property associated with the particle and to produce a control command for sorting the particle based on sorting criteria associated with particle properties, and an actuator to direct the particle into one of a plurality of output paths of the particle flow device in real-time. |
| FILED | Thursday, May 20, 2021 |
| APPL NO | 17/326312 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/36 (20130101) G01J 3/46 (20130101) G01J 3/51 (20130101) G01J 3/0208 (20130101) G01J 3/0229 (20130101) G01J 3/4406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) G01N 15/1429 (20130101) G01N 15/1475 (20130101) Original (OR) Class G01N 15/1484 (20130101) G01N 2015/149 (20130101) G01N 2015/1006 (20130101) G01N 2015/1402 (20130101) G01N 2015/1497 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11668711 — Multiplexed diagnostic assay for iron and vitamin A deficiency and methods of use thereof
| US 11668711 | Mehta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERISTY (Ithaca, New York) |
| INVENTOR(S) | Saurabh Mehta (Ithaca, New York); David Erickson (Ithaca, New York); Zhengda Lu (Ithaca, New York) |
| ABSTRACT | A diagnostic assay strip includes a first layer that includes an iron mobile labelled specific binding partner that will bind to and iron biomarker from a sample and produce an iron complex and a vitamin A mobile labelled specific binding partner that will bind to a vitamin A biomarker from the sample and produce a vitamin A complex. A second layer includes iron and vitamin A test regions, and a control region. The iron test region has immobilized specific binding partners that will bind to the iron complex. The vitamin A test region has immobilized vitamin A biomarker that will bind to vitamin A mobile labelled specific binding partner, which is not bound to the vitamin A biomarker, passing from the first layer to the second layer. The control region has a moiety which will non-specifically bind to and immobilize the iron and vitamin A labelled specific binding partners. Methods of using the diagnostic assay strip are also discussed. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/763707 |
| ART UNIT | 1677 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/82 (20130101) G01N 33/84 (20130101) G01N 33/582 (20130101) G01N 33/6803 (20130101) G01N 33/54386 (20130101) G01N 33/54388 (20210801) Original (OR) Class G01N 2021/6441 (20130101) G01N 2333/705 (20130101) G01N 2333/4737 (20130101) G01N 2458/00 (20130101) G01N 2470/04 (20210801) G01N 2470/10 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11669976 | Datta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Sandeep Robert Datta (Cambridge, Massachusetts); Matthew J. Johnson (Cambridge, Massachusetts); Alexander B. Wiltschko (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods are disclosed to objectively identify sub-second behavioral modules in the three-dimensional (3D) video data that represents the motion of a subject. Defining behavioral modules based upon structure in the 3D video data itself—rather than using a priori definitions for what should constitute a measurable unit of action—identifies a previously-unexplored sub-second regularity that defines a timescale upon which behavior is organized, yields important information about the components and structure of behavior, offers insight into the nature of behavioral change in the subject, and enables objective discovery of subtle alterations in patterned action. The systems and methods of the invention can be applied to drug or gene therapy classification, drug or gene therapy screening, disease study including early detection of the onset of a disease, toxicology research, side-effect study, learning and memory process study, anxiety study, and analysis in consumer behavior. |
| FILED | Friday, October 30, 2020 |
| APPL NO | 17/085510 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) A61B 5/1116 (20130101) A61B 5/1128 (20130101) Image Data Processing or Generation, in General G06T 7/66 (20170101) G06T 7/215 (20170101) Original (OR) Class G06T 7/251 (20170101) G06T 7/254 (20170101) G06T 2207/10016 (20130101) G06T 2207/10021 (20130101) G06T 2207/10028 (20130101) G06T 2207/20032 (20130101) G06T 2207/20064 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670421 | Longmire et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Medable Inc. (Palo Alto, California) |
| ASSIGNEE(S) | Medable Inc. (Palo Alto, California) |
| INVENTOR(S) | Michelle Longmire (Palo Alto, California); Ingrid Oakley-Girvan (Henderson, California); Nick Moss (Los Alamos, New Mexico); Reem Yunis (Menlo Park, California); Anushka Manoj Gupta (Raleigh, North Carolina) |
| ABSTRACT | The instant system and method will be a scalable and flexible software platform to agnostically capture wearable, implantable, or external device data and create a digital biomarker for various disease conditions, care and analysis. The system and method also provides an informatics tool for automated data aggregation, integration, and machine learning algorithms to uniformly compare/contrast/couple data streams as a function of patient and context over time. The focus is on user engagement and usability, accessibility and reporting to the clinical care team, and usability by researchers interested in analyzing data and outcomes. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/219867 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/00 (20180101) G16H 40/67 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/50 (20180101) G16H 50/70 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11666216 | Scherer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Axel Scherer (Barnard, Vermont); Peter A Petillo (Lawrence, Kansas); Samson Chen (Pasadena, California); Azita Emami (Pasadena, California) |
| ABSTRACT | A smart cage includes radiofrequency transceivers and tags attached to laboratory animals. The tags include sensors to detect monitorable conditions of the laboratory animals. The sensors include working electrodes, counter electrodes, reference electrodes, and potentiostats. The top surface of the electrodes is coated with ionophores or enzymes which detect the monitorable conditions of the laboratory animals. |
| FILED | Wednesday, May 23, 2018 |
| APPL NO | 15/987843 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 1/031 (20130101) A01K 11/006 (20130101) A01K 29/00 (20130101) Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/002 (20130101) Original (OR) Class A61B 5/1113 (20130101) A61B 5/1486 (20130101) A61B 5/6832 (20130101) A61B 5/6868 (20130101) A61B 5/14532 (20130101) A61B 5/14539 (20130101) A61B 5/14542 (20130101) A61B 5/14546 (20130101) A61B 5/14865 (20130101) A61B 2503/40 (20130101) A61B 2503/42 (20130101) Transmission H04B 5/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666462 | van der Merwe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| ASSIGNEE(S) | DEKA PRODUCTS LIMITED PARTNERSHIP (Manchester, New Hampshire) |
| INVENTOR(S) | Dirk Albertus van der Merwe (Canterbury, New Hampshire); Gregory R. Lanier (Manchester, New Hampshire); John M. Kerwin (Manchester, New Hampshire); Gerald M. Guay (Greenville, New Hampshire); N. Christopher Perry (Manchester, New Hampshire); Susan D. Dastous (Litchfield, New Hampshire) |
| ABSTRACT | A control system for control of a prosthetic device having a plurality of actuators receives an orientation signal indicative of a desired movement. The control system evaluates whether the prosthetic device may move as desired with a current angle of rotation and commands at least one actuator to move the prosthetic device as desired by maintaining the current angle of rotation or by adjusting the angle of rotation if the prosthetic device cannot move as desired with the current angle. The control system may alternate between commanding a first subset of actuators and a second subset of actuators each time the orientation signal is indicative of a neutral position. The control system may include a position sensor and a compliance sensor and may command at least one actuator based on a combination of positional control using the position sensor and force control using the compliance sensor. |
| FILED | Monday, August 05, 2019 |
| APPL NO | 16/531641 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/389 (20210101) A61B 5/1036 (20130101) A61B 5/4528 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/70 (20130101) Original (OR) Class A61F 2/72 (20130101) A61F 2/581 (20130101) A61F 2/582 (20130101) A61F 2/583 (20130101) A61F 2/585 (20130101) A61F 2/586 (20130101) A61F 2002/543 (20130101) A61F 2002/546 (20130101) A61F 2002/587 (20130101) A61F 2002/701 (20130101) A61F 2002/704 (20130101) A61F 2002/705 (20130101) A61F 2002/707 (20130101) A61F 2002/762 (20130101) A61F 2002/764 (20130101) A61F 2002/5018 (20130101) A61F 2002/5021 (20130101) A61F 2002/6827 (20130101) A61F 2002/7625 (20130101) A61F 2002/7635 (20130101) A61F 2002/7645 (20130101) A61F 2002/7685 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666580 | Polyak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kornelia Polyak (Brookline, Massachusetts); Shaokun Shu (Brookline, Massachusetts); James E. Bradner (Weston, Massachusetts); Charles Yang Lin (Houston, Texas) |
| ABSTRACT | The present disclosure provides combination therapy comprising a BET inhibitor and a protein phosphatase 2A (PP2A) activator, a B-cell lymphoma-2 (Bcl-2) inhibitor, a B-cell lymphoma-extra large (Bcl-xl) inhibitor, a casein kinase 2 (CK2) inhibitor, and/or a mediator complex subunit 1 (MED1) for cancer. The combination therapy is expected to be synergistic in treating the cancer, compared to the monotherapy. Methods for identifying a subject having a cancer that is resistant to or at risk of developing resistance to bromodomain and extra terminal (BET) inhibitor therapy are also provided. |
| FILED | Wednesday, August 10, 2016 |
| APPL NO | 15/751914 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/137 (20130101) A61K 31/551 (20130101) Original (OR) Class A61K 31/551 (20130101) A61K 31/635 (20130101) A61K 31/5415 (20130101) A61K 31/5415 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666611 | Bry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Lynn Bry (Jamaica Plain, Massachusetts); Georg Gerber (Newton, Massachusetts); Jessica Allegretti (Boston, Massachusetts); Richard Lavin (Brighton, Massachusetts); Nicholas DiBenedetto (Meford, Massachusetts) |
| ABSTRACT | Described herein are methods and compositions for the use of treating and/or preventing Clostridium difficile infections, including recurrent C. difficile infections, in a subject. Aspects of the technology relate to administering to a subject in need thereof a composition comprising a defined therapeutic microbiota comprising, e.g. Clostridial species. Also described herein are biomarker profiles, including a biomarker profile comprising two groups of Clostridial species, that is predictive of the likelihood of recurrent C. difficile infection and/or susceptibility to initial C. difficile infection. |
| FILED | Tuesday, December 11, 2018 |
| APPL NO | 16/771979 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0031 (20130101) A61K 9/0053 (20130101) A61K 35/741 (20130101) A61K 35/742 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/34 (20130101) A61K 47/42 (20130101) A61K 47/183 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/06 (20130101) C12Q 1/26 (20130101) C12Q 1/37 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/50 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666647 | Hazlett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ALBANY MEDICAL COLLEGE (Albany, New York) |
| ASSIGNEE(S) | ALBANY MEDICAL COLLEGE (Albany, New York) |
| INVENTOR(S) | Karsten Hazlett (East Berne, New York); Kristen M. Tummillo (Union, New Jersey); Edmund J. Gosselin (Delanson, New York) |
| ABSTRACT | An approach for modifying multiple types of bacteria to produce surface modifications that enhance the immunologic response when used as a vaccine. A series of plasmids (pYF, pYFC, pYFP, pSF, pSPF, and pSCF) may be used to transform bacteria which then produce surface-exposed ligands that bind to complement receptors on antigen presenting cells. When modified bacteria are used as a vaccine, the vaccine recipients produce significantly higher titers of specific antibodies and are better protected against challenges from the disease-causing bacteria. |
| FILED | Tuesday, September 29, 2020 |
| APPL NO | 17/036526 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) A61K 38/1725 (20130101) A61K 39/02 (20130101) Original (OR) Class A61K 2039/55516 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 2310/3517 (20130101) C12N 2800/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666786 | Opperman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Orbital Research Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Anthony Opperman (Wickliffe, Ohio); Frederick Lisy (Euclid, Ohio) |
| ABSTRACT | The present invention is a wearable device for comprehensive bio-monitoring of physiologic metrics to determine metabolic, pulmonary and cardiac function and oxygen saturation measurements from breathing mask apparatuses. The device non-invasively monitors the physiologic profile of the subject, and is capable of detecting physiologic changes, predicting onset of symptoms, and alerting the wearer or another person or system. In some embodiments, the device comprises both a wearable sensor suite and a portable gas composition and flow analysis system. In preferred embodiments, it comprises a miniaturized non-invasive sensor suite for detecting physiologic changes to detect dangerous breathing or other health conditions. The system utilizes advanced fast-response sensors with improved efficiency and lifespan, and provides rapid analysis for substantially real-time monitoring of the subject's present condition to predict, mitigate and/or prevent the onset of dangerous conditions. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/987573 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 5/097 (20130101) A61B 5/0873 (20130101) A61B 5/7275 (20130101) A61B 2503/12 (20130101) A61B 2560/0223 (20130101) A61B 2560/0252 (20130101) Devices, Apparatus or Methods for Life-saving A62B 7/14 (20130101) A62B 9/006 (20130101) Original (OR) Class A62B 18/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667379 | Milgram |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Judah H. Milgram (Washington, District of Columbia) |
| ABSTRACT | Systems, apparatus, and methods are provided for retrieving data from remotely deployed sensor systems. Flight control systems are also provided for maintaining the orientation of a high gain antenna affixed to an aircraft relative to a stationary or nearly stationary transceiver. |
| FILED | Tuesday, November 17, 2020 |
| APPL NO | 16/950441 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Original (OR) Class Unmanned aerial vehicles [UAV]; equipment therefor B64U 2101/30 (20230101) B64U 2201/20 (20230101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0607 (20130101) G05D 1/0808 (20130101) Antennas, i.e Radio Aerials H01Q 1/287 (20130101) H01Q 3/005 (20130101) H01Q 19/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667407 | Yakimenko et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Oleg Yakimenko (Seaside, California); Edward Hanlon (Mt. Pleasant, South Carolina) |
| ABSTRACT | Embodiments in accordance with the invention address potential co-orbital threats to a spacecraft through the use of a plurality of evasion pattern maneuvers selected to prevent a rendezvous with a potential co-orbital threat from occurring within a finite horizon. Embodiments in accordance with the invention maintain separation from the potential co-orbital threat while minimizing a defending spacecraft's fuel consumption. |
| FILED | Wednesday, April 22, 2020 |
| APPL NO | 16/855205 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/10 (20130101) B64G 1/36 (20130101) B64G 1/52 (20130101) Original (OR) Class B64G 1/242 (20130101) Electric Digital Data Processing G06F 17/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667546 | Popovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jovan Popovic (Ventura, California); John Joseph Kornuc (Malibu, California) |
| ABSTRACT | A drop-in treatment apparatus and system for PFAS-impacted liquids. The drop-in treatment apparatus and system may comprise one or more cartridges having a plurality openings; one or more mesh containers disposed within the one or more cartridges; one or more tethers; a submersible pump coupled to the cartridges via the tethers; and a power source electrically coupled to the submersible pump. The drop-in treatment apparatus may further comprise a plurality of prescribed masses of sorbent or resin filled within the mesh containers, such that the prescribed masses of sorbent or resin are disposed within the cartridges. The prescribed masses of sorbent or resin may be configured to remove PFAS compounds from a liquid and may be in the range of 0.1-50,000 milligrams per milliliter of liquid volume to be treated. The sorbent may be pyrogenic carbon, granular activated carbon, biochar, zeolite, aluminosilicates, and combinations thereof. |
| FILED | Friday, April 09, 2021 |
| APPL NO | 17/226543 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 35/027 (20130101) B01D 35/0273 (20130101) B01D 35/0276 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2220/62 (20130101) B01J 2220/66 (20130101) Dispensing, Delivering or Transferring Liquids, Not Otherwise Provided for B67D 7/58 (20130101) B67D 7/68 (20130101) B67D 7/76 (20130101) B67D 7/766 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/001 (20130101) C02F 1/42 (20130101) C02F 1/283 (20130101) Original (OR) Class C02F 1/685 (20130101) C02F 1/687 (20130101) C02F 2001/422 (20130101) C02F 2101/36 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 23/02 (20130101) F04B 23/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667576 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Xinghang Zhang (West Lafayette, Indiana); Haiyan Wang (West Lafayette, Indiana); Jin Li (West Lafayette, Indiana); Jaehun Cho (West Lafayette, Indiana); Xin Li Phuah (West Lafayette, Indiana); Han Wang (Richland, Washington) |
| ABSTRACT | Methods of determining and controlling the deformability of ceramic materials, as a nonlimiting example, YSZ, particularly through the application of a flash sintering process, and to ceramic materials produced by such methods. Such a method includes providing a nanocrystalline powder of a ceramic material, making a compact of the powder, and subjecting the compact to flash sintering by applying an electric field and thermal energy to the compact. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/811814 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 23/08 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/90 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/48 (20130101) Original (OR) Class C04B 35/64 (20130101) C04B 2235/549 (20130101) C04B 2235/666 (20130101) C04B 2235/3246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667669 | Bassett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ROWAN UNIVERSITY (Glassboro, New Jersey); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| ASSIGNEE(S) | Rowan University (Glassboro, New Jersey); The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Alexander W. Bassett (Mullica Hill, New Jersey); Joseph F. Stanzione, III (Wilmington, Delaware); John J. La Scala (Wilmington, Delaware) |
| ABSTRACT | The present invention relates to the unexpected discovery of novel monomer compounds capable of crosslinking interpenetrating polymer networks (IPNs). In certain embodiments, the monomer compounds of the invention each comprise at least one methacrylate functionality capable of forming polymeric bonds with other methacrylate and vinyl functionalities, and at least one epoxide functionality capable of forming polymeric bonds with epoxide functionalities, amine functionalities, and/or reactive oxygen species. |
| FILED | Tuesday, August 13, 2019 |
| APPL NO | 16/538989 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 303/22 (20130101) C07D 493/04 (20130101) Steroids C07J 53/002 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 20/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667676 | Chong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Lucy S. Chong (Pasadena, California); Ronghui Zhu (Pasadena, California); Xiaofei Ge (Beijing, China PRC); Michael B. Elowitz (Pasadena, California); Mark W. Budde (Arcadia, California) |
| ABSTRACT | Disclosed herein include methods, compositions, and kits suitable for use in thresholding of protein signals. There are provided, in some embodiments, synthetic protein circuits that respond to inputs only above or below a certain threshold concentration. In some embodiments, the threshold value itself is tunable. Methods of treating a disease or disorder characterized by aberrant signaling are provided in some embodiments. |
| FILED | Thursday, January 09, 2020 |
| APPL NO | 16/738664 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/001 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667682 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fuzhong Zhang (St. Louis, Missouri); Christopher H. Bowen (St. Louis, Missouri); Bin Dai (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Fuzhong Zhang (St. Louis, Missouri); Christopher H. Bowen (St. Louis, Missouri); Bin Dai (St. Louis, Missouri) |
| ABSTRACT | The present disclosure is directed to systems and methods for synthesizing a spidroin. In some embodiments, the methods comprise synthesizing a monomer in vivo in a heterologous host, the monomer comprising an N-terminus IntC domain and a C-terminus IntN domain, and post-translationally polymerizing the synthesized monomer via in vitro split-intein mediated polymerization. |
| FILED | Friday, December 13, 2019 |
| APPL NO | 16/713643 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/05 (20190201) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2089/00 (20130101) B29K 2995/0088 (20130101) Peptides C07K 14/43518 (20130101) Original (OR) Class C07K 2319/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 15/70 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/02 (20130101) D01D 5/06 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667733 | Liebfarth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Frank Liebfarth (Carrboro, North Carolina); Aaron Teator (Chapel Hill, North Carolina) |
| ABSTRACT | Disclosed herein are isotactic polyvinyl ethers and improved methods of making same. The method disclosed herein can produce polyvinyl ethers having a higher isotacticity as compared to polyvinyl ethers prepared with conventional methods. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 17/269247 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 16/18 (20130101) C08F 16/20 (20130101) Original (OR) Class C08F 116/18 (20130101) C08F 116/20 (20130101) C08F 216/18 (20130101) C08F 216/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667737 | Harvey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin G. Harvey (Ridgecrest, California); Andrew Chafin (Ridgecrest, California); Matthew C. Davis (Ridgecrest, California) |
| ABSTRACT | A method for making thermosetting polyimides from resveratrol including converting resveratrol to trisaniline, reacting trisaniline with one or more dianhydride and thermosetting endcap to form amic acid, thermally imidizing amic acid to form polyimide oligomer, and cross-linking polyimide oligomer with heat and pressure to generate polyimide thermoset. |
| FILED | Thursday, October 28, 2021 |
| APPL NO | 17/513133 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/123 (20130101) Acyclic or Carbocyclic Compounds C07C 209/22 (20130101) C07C 211/51 (20130101) C07C 217/90 (20130101) Heterocyclic Compounds C07D 235/20 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 132/08 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667910 | Funkner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CureVac Manufacturing GmbH (Tübingen, Germany) |
| ASSIGNEE(S) | CureVac Manufacturing GmbH (Tübingen, Germany) |
| INVENTOR(S) | Andreas Funkner (Tübingen, Germany); Stefanie Dorner (Tübingen, Germany); Stefanie Sewing (Tübingen, Germany); Johannes Kamm (Tübingen, Germany); Norbert Broghammer (Tübingen, Germany); Thomas Ketterer (Gomaringen, Germany); Thorsten Mutzke (Reutlingen, Germany) |
| ABSTRACT | The present invention relates to method for producing and purifying RNA comprising the steps of providing DNA encoding the RNA; transcription of the DNA into RNA; and conditioning and/or purifying of the solution comprising transcribed RNA by one or more steps of tangential flow filtration (TFF). |
| FILED | Thursday, February 03, 2022 |
| APPL NO | 17/591978 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Separation B01D 61/145 (20130101) B01D 71/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1017 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/02 (20130101) G01N 2030/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667999 | Trivedi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UES INC. (Dayton, Ohio); MIDWEST THERMAL-VAC INC (Kenosha, Wisconsin); AKTIEBOLAGET SKF (Gothenburg, Sweden) |
| ASSIGNEE(S) | UES INC. (Dayton, Ohio); MIDWEST THERMAL-VAC INC. (Kenosha, Wisconsin); AKTIEBOLAGET SKF (Gothenburg, Sweden) |
| INVENTOR(S) | Hitesh K. Trivedi (Fairborn, Ohio); Frederick J. Otto (Pleasant Prairie, Wisconsin); Timothy W. Piazza (Jamestown, New York); Bryan A. McCoy (Jamestown, New York); Rabi S. Bhattacharya (Beavercreek, Ohio) |
| ABSTRACT | A method for producing a case-hardened martensitic stainless steel article includes: providing an article comprised, at least in part, of a martensitic stainless steel, carburizing the article within a temperature range of 1625° F.-1680° F. (885° C.-916° C.), and then carbo-nitriding the article within a temperature range of 1575° F.-1625° F. (857° C.-885° C.). An article, such as a bearing ring, comprising such a case-hardened martensitic stainless steel is also disclosed. |
| FILED | Thursday, July 19, 2018 |
| APPL NO | 16/039564 |
| ART UNIT | 1738 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/06 (20130101) C21D 1/25 (20130101) C21D 6/005 (20130101) C21D 6/007 (20130101) C21D 9/40 (20130101) C21D 2211/008 (20130101) Alloys C22C 5/04 (20130101) C22C 19/03 (20130101) C22C 38/02 (20130101) C22C 38/04 (20130101) C22C 38/44 (20130101) C22C 38/46 (20130101) C22C 38/48 (20130101) C22C 38/52 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/32 (20130101) Original (OR) Class C23C 8/58 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 33/62 (20130101) F16C 33/64 (20130101) F16C 2202/04 (20130101) F16C 2204/70 (20130101) F16C 2240/06 (20130101) F16C 2240/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668023 | Truong |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Quoc T Truong (Hyde Park, Massachusetts) |
| ABSTRACT | The disclosed subject matter relates to a superomniphobic fiber including a core having a surface and at least one channel and a plurality of nanoparticles disposed in the material core at least partially protruding from the surface of the material core. |
| FILED | Friday, April 15, 2022 |
| APPL NO | 17/721400 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/253 (20130101) Original (OR) Class D01D 10/02 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 8/06 (20130101) D01F 8/10 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2321/06 (20130101) D10B 2321/022 (20130101) D10B 2401/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668387 | Dunbar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Caterpillar Inc. (Peoria, Illinois) |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | James Dunbar (East Peoria, Illinois); Lee David Kress (Lafayette, Indiana); Dongyao Wang (Rochester Hills, Michigan) |
| ABSTRACT | A damper and pulley assembly for an internal combustion engine is disclosed. The damper and pulley assembly, including a pulley closely fitted between two dampers, is configured to have increased air movement for heat dissipation while conforming to low spacing requirements of an engine compartment. The pulley can have multiple slots along its two side surfaces and openings located in the slots. The slots and openings of the pulley are aligned with openings of the two dampers, and facilitate air movement through the pulley and around the dampers. |
| FILED | Monday, June 13, 2022 |
| APPL NO | 17/839328 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 25/02 (20130101) B60K 2025/022 (20130101) Gearing F16H 55/36 (20130101) Original (OR) Class F16H 57/0416 (20130101) F16H 2055/366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668497 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Nanfang Yu (Fort Lee, New Jersey); Jyotirmoy Mandal (New York, New York); Adam Overvig (New York, New York); Norman Nan Shi (San Jose, California); Meng Tian (Fort Lee, New Jersey) |
| ABSTRACT | Systems and methods for radiative cooling and heating are provided. For example, systems for radiative cooling can include a top layer including one or more polymers, where the top layer has high emissivity in at least a portion of the thermal spectrum and an electromagnetic extinction coefficient of approximately zero, absorptivity of approximately zero, and high transmittance in at least a portion of the solar spectrum, and further include a reflective layer including one or more metals, where the reflective layer has high reflectivity in at least a portion of the solar spectrum. |
| FILED | Monday, March 21, 2022 |
| APPL NO | 17/699789 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/18 (20130101) B32B 27/283 (20130101) B32B 33/00 (20130101) B32B 2305/18 (20130101) B32B 2305/30 (20130101) B32B 2307/30 (20130101) B32B 2307/416 (20130101) B32B 2311/24 (20130101) B32B 2333/12 (20130101) B32B 2383/00 (20130101) B32B 2386/00 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 10/40 (20180501) F24S 70/30 (20180501) F24S 70/60 (20180501) F24S 70/225 (20180501) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/003 (20130101) Original (OR) Class Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 2245/06 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668533 | Lockwood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Windsor Locks, Connecticut) |
| INVENTOR(S) | William T. Lockwood (Windsor Locks, Connecticut); Matthew William Miller (Enfield, Connecticut); Luke J. Mayo (Coventry, Connecticut) |
| ABSTRACT | A method for manufacturing a heat exchanger includes stacking a plurality of parting sheets, a plurality of lengthwise closure bars, and a plurality of widthwise closure bars to form a rectangular first heat exchanger section. The first heat exchanger section includes at least one widthwise passage extending between a pair of the widthwise closure bars and at least one lengthwise passage extending between a pair of the lengthwise closure bars. The method also includes brazing the rectangular first heat exchanger section together and cutting a first side and a second side of the rectangular first heat exchanger section to give the first heat exchanger section a tapered-trapezoid profile. The method further includes brazing an end of a second heat exchanger section to the first or second side of the first heat exchanger section. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/345307 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 1/0012 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/0246 (20130101) F28D 1/05366 (20130101) F28D 7/005 (20130101) F28D 9/0025 (20130101) F28D 9/0062 (20130101) F28D 2021/0021 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/025 (20130101) Original (OR) Class F28F 9/26 (20130101) F28F 2210/10 (20130101) F28F 2240/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668556 | Fujimoto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | James G. Fujimoto (Medford, Massachusetts); Eric Michael Moult (Cambridge, Massachusetts); ByungKun Lee (Cambridge, Massachusetts) |
| ABSTRACT | A computer-implemented method of imaging an object, and an optical coherent tomography (OCT) imaging system implementing same. The method comprises acquiring a three-dimensional optical coherence tomography (OCT) data set representing an object, wherein the OCT data set includes at least a first and a second three-dimensional data subsets, each element of the OCT data set having a respective sampling period, wherein at least a first element of the first data subset represents a point in space that is not represented by any element of the second subset, and at least one element of the second subset has a sampling period different from the sampling period of the first element of the first subset; processing at least the first and the second data subsets according to at least one imaging modality, thereby generating at least a first and a second processed data subsets, each processed data subset representing the object; and generating a composite image representing the object based on at least the first and the second processed data subsets. |
| FILED | Friday, May 04, 2018 |
| APPL NO | 16/611011 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) A61B 3/107 (20130101) A61B 3/1233 (20130101) A61B 3/1241 (20130101) A61B 5/0035 (20130101) A61B 5/0066 (20130101) A61B 5/0261 (20130101) A61B 5/0285 (20130101) A61B 5/02014 (20130101) A61B 5/7425 (20130101) A61B 5/14535 (20130101) A61B 5/14552 (20130101) A61B 90/39 (20160201) A61B 2090/3937 (20160201) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02045 (20130101) G01B 9/02091 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668614 | Willens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Materials and Devices (Reno, Nevada) |
| ASSIGNEE(S) | Advanced Materials and Devices, Inc. (Reno, Nevada) |
| INVENTOR(S) | Kyle Willens (Carson City, Nevada); Blake Muzinich (Reno, Nevada); Barkan Kavlicoglu (Reno, Nevada); Faramarz Gordaninejad (Reno, Nevada) |
| ABSTRACT | A wearable universal blast sensor includes an underwater pressure sensing transducer and at least one blast parameter sensing transducer to measure a blast parameter from the blast other than pressure, an analog-to-digital converter having an analog input and a digital output, the analog input coupled to the pressure sensing transducer and a digital output, a rolling memory buffer coupled to the digital output of the analog-to-digital converter, at least one controller coupled to the rolling memory buffer and configured to store a time sequence of digital pressure signals from the digital output of the analog-to-digital converter, write into a blast event memory data from the rolling memory buffer including data corresponding to the blast event if one of the digital pressure signals exceeds a set first threshold, generate a first blast magnitude indicator signal if any of the digital pressure signals exceeds a second set threshold. |
| FILED | Tuesday, April 19, 2022 |
| APPL NO | 17/724010 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/14 (20130101) Original (OR) Class G01L 19/147 (20130101) G01L 19/149 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11669009 | Sreenivasan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Sidlgata V. Sreenivasan (Austin, Texas); Shrawan Singhal (Austin, Texas); Ovadia Abed (Austin, Texas); Lawrence Dunn (Austin, Texas); Paras Ajay (Austin, Texas); Ofodike Ezekoye (Austin, Texas) |
| ABSTRACT | A method for fabricating patterns on a flexible substrate in a roll-to-roll configuration. Drops of a monomer diluted in a solvent are dispensed on a substrate, where the drops spontaneously spread and merge with one another to form a liquid resist formulation. The solvent is evaporated (e.g., blanket evaporation) from the liquid resist formulation followed by selective multi-component resist film evaporation resulting in a non-uniform and substantially continuous film on the substrate. The gap between the film on the substrate and a template is closed such that the film fills the features of the template. After cross-linking the film to polymerize the film, the template is separated from the substrate thereby leaving the polymerized film on the substrate. |
| FILED | Thursday, August 03, 2017 |
| APPL NO | 16/322842 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/24 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11669661 | Mirzendehdel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Amirmassoud Mirzendehdel (San Mateo, California); Morad Behandish (Mountain View, California); Saigopal Nelaturi (Mountain View, California) |
| ABSTRACT | A representation of an initial design domain, at least one subtractive tool assembly, machine degrees of freedom, and a termination criterion are used to iteratively generate intermediate part designs by redistributing the material within the design domain. A measure of inaccessibility of exteriors of the intermediate part designs by the at least one subtractive manufacturing tool assembly are generated. The measure of inaccessibility is used to inform generation of an intermediate part design at a next iteration. The iterative algorithm is terminated when the termination criterion is satisfied, the result of the iterative algorithm being a part design accessible for subtractive manufacturing. |
| FILED | Monday, June 15, 2020 |
| APPL NO | 16/901187 |
| ART UNIT | 2147 — Multiplex and VoIP |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) G05B 2219/32015 (20130101) Electric Digital Data Processing G06F 30/17 (20200101) G06F 30/23 (20200101) Original (OR) Class G06F 2111/04 (20200101) G06F 2119/18 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670731 | Lo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the Unversity of California (Oakland, California) |
| INVENTOR(S) | Yu-Hwa Lo (San Diego, California); David Hall (San Diego, California); Yu-Hsin Liu (San Diego, California); Zihan Xu (La Jolla, California); Lujiang Yan (La Jolla, California) |
| ABSTRACT | Methods, systems, and devices are disclosed for low noise and high efficiency photoelectric amplification based on cycling excitation process (CEP). In some aspects, a device for amplifying signals of light-induced photocurrent includes an anode connected to a positive terminal of a voltage source; a disordered material layer coupled to the anode, wherein the disordered material layer is structured to have a thickness of 100 nm or less; and a cathode coupled to the disordered material layer and connected to a negative terminal of the voltage source, in which the device is operable to amplify photoexcited carriers based on photon absorption to produce an external quantum efficiency of the device that is at least 100%. |
| FILED | Tuesday, February 13, 2018 |
| APPL NO | 16/486482 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0376 (20130101) H01L 31/1075 (20130101) Original (OR) Class H01L 31/03762 (20130101) H01L 31/03765 (20130101) H01L 51/4213 (20130101) H01L 2031/0344 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670759 | Hopkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Brandon J. Hopkins (Bethesda, Maryland); Joseph F. Parker (Riva, Maryland); Jeffrey W. Long (Alexandria, Virginia); Debra R. Rolison (Arlington, Virginia) |
| ABSTRACT | Disclosed are methods of making porous zinc electrodes. Taken together, the steps are: forming a mixture of water, a soluble compound that increases the viscosity of the mixture, an insoluble porogen, and metallic zinc powder; placing the mixture in a mold to form a sponge; optionally drying the sponge; placing the sponge in a metal mesh positioned to allow air flow through substantially all the openings in the mesh; heating the sponge in an inert atmosphere at a peak temperature of 200 to 420° C. to fuse the zinc particles to each other to form a sintered sponge; and heating the sintered sponge in an oxygen-containing atmosphere at a peak temperature of 420 to 700° C. to form ZnO on the surfaces of the sintered sponge. The heating steps burn out the porogen. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375381 |
| ART UNIT | 1752 — Semiconductors/Memory |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/11 (20130101) B22F 3/1007 (20130101) B22F 3/1143 (20130101) B22F 2301/30 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/30 (20130101) Original (OR) Class H01M 4/38 (20130101) H01M 4/244 (20130101) H01M 4/0433 (20130101) H01M 4/0471 (20130101) H01M 10/24 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670848 | Kwon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wichita State University (Wichita, Kansas) |
| ASSIGNEE(S) | WICHITA STATE UNIVERSITY (Wichita, Kansas) |
| INVENTOR(S) | Hyuck M. Kwon (Wichita, Kansas); Krittetash Pinoyoanuntapong (Wichita, Kansas); Khanh Pham (Albuquerque, New Mexico) |
| ABSTRACT | The present disclosure provides an anti jamming system for a wireless communication system an antenna array comprising N antenna elements. At least two multiphase filters being connected to the antenna array and configured to receive an antenna element signal from each one of the N antenna elements. An anti-jamming system for a wireless communication system comprising an antenna array comprising N antenna elements and a filter configured to attenuate jamming signals from sources that is greater than, less than, or equal to N. An anti-jamming system for a wireless communication system comprising a multiphase filter connected to the antenna array to receive an antenna element signal from each antenna element of the antenna array, the multiphase filters comprising a first phase and a second phase, wherein the first phase of the multiphase filter executes a Frost's algorithm and the second phase of the multiphase filter executes a Maximin algorithm. |
| FILED | Tuesday, August 25, 2020 |
| APPL NO | 17/002452 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/246 (20130101) H01Q 3/2605 (20130101) Original (OR) Class Transmission H04B 7/0617 (20130101) Secret Communication; Jamming of Communication H04K 3/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11671063 | Clerk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Aashish Clerk (Chicago, Illinois); Alexander McDonald (Chicago, Illinois) |
| ABSTRACT | Optimally detuned parametric amplification amplifies a signal in a resonator that is driven off-resonance, with respect to a signal mode, using a far-detuned pump. This pump establishes a parametric drive strength, and is “far-detuned” in that its detuning from the signal mode is greater than the drive strength. The amplitude and frequency of the pump are chosen so that the eigenfrequency of the resulting Bogoliobov mode matches a photonic loss rate of the Bogoliobov mode. In this case, a signal coupled into the Bogoliobov mode will be amplified with a gain that is broader and flatter than that achieved with conventional parametric amplification, and is not limited by a gain-bandwidth product. Optimally detuned parametric amplification may be used for degenerate or non-degenerate parametric amplification, and may be used to amplify microwaves, light, electronic signals, acoustic waves, or any other type of signal that can be amplified using conventional parametric amplification. |
| FILED | Sunday, December 13, 2020 |
| APPL NO | 17/756481 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/31 (20130101) G02F 1/392 (20210101) Amplifiers H03F 3/189 (20130101) H03F 7/04 (20130101) Original (OR) Class H03F 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11671436 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
| INVENTOR(S) | Jiejun Xu (Diamond Bar, California); Kang-Yu Ni (Calabasas, California); Alexei Kopylov (Pasadena, California); Shane M. Roach (San Francisco, California); Tsai-Ching Lu (Thousand Oaks, California) |
| ABSTRACT | Described is a system for producing indicators and warnings of adversarial activities. The system receives multiple networks of transactional data from different sources. Each node of a network of transactional data represents an entity, and each edge represents a relation between entities. A worldview graph is generated by merging the multiple networks of transactional data. Suspicious subgraph regions related to an adversarial activity are identified in the worldview graph through activity detection. The suspicious subgraph regions are used to generate and transmit an alert of the adversarial activity. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/021542 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/24578 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11671452 | Halford |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Caliola Engineering, LLC (Colorado Springs, Colorado) |
| ASSIGNEE(S) | CALIOLA ENGINEERING, LLC (Colordo Springs, Colorado) |
| INVENTOR(S) | Thomas R. Halford (Colorado Springs, Colorado) |
| ABSTRACT | A system and method for cryptographically securing data communications between a group of networked devices establishes and maintains an overlay network at the Application Layer, on top of a unicast routing service provided at the Internetworking Layer. The overlay network provides first, the routes that are used to deliver multicast datagrams and second, the cryptographic keys used to secure multicast datagrams. A common cryptographic key is established between all members of each group, and end-to-end encryption ensures that multicast datagrams can be accessed only by authorized group members. In other embodiments, keys are established between pairs of adjacent devices in the overlay network, and hop-by-hop encryption ensures that multicast datagrams can be accessed only by overlay network members. |
| FILED | Thursday, June 04, 2020 |
| APPL NO | 16/892883 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0841 (20130101) H04L 63/065 (20130101) H04L 63/168 (20130101) Original (OR) Class H04L 63/0435 (20130101) H04L 63/0464 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11671817 | Stroman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Richard O. Stroman (Washington, District of Columbia); Karen Swider-Lyons (Alexandria, Virginia); Eric A. Leadbetter (Columbia, Maryland); Christopher Buesser (Washington, District of Columbia) |
| ABSTRACT | An embodiment of the invention includes a non-transitory computer-readable medium storing instructions that, when executed by a computer, cause the computer to carry out a method for scheduling at least one activity to achieve a time-varying energy balance of a power system. A mission plan for a mission is received. The mission plan includes at least one activity and at least one route. Each route of the at least one route includes at least one time and at least one location. A plurality of power load identifications is received for at least one time-varying power load for use in the mission plan. A plurality of energy storage device identifications is received for at least one energy storage device. Based on the plurality of power load identifications, a power requirement required to complete the mission plan is determined using the at least one power load. Based at least in part on the mission plan and the plurality of energy storage device identifications, an available power for the mission is determined. The at least one activity along the at least one route is scheduled based on the power requirement and the available energy. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/160569 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Electric Digital Data Processing G06F 1/28 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/00 (20130101) H02J 3/003 (20200101) H02J 3/381 (20130101) H02J 7/35 (20130101) H02J 2203/20 (20200101) H02J 2300/20 (20200101) H02J 2300/24 (20200101) Wireless Communication Networks H04W 8/06 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/00 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 40/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11672106 | Duffy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Jason C. Duffy (Granby, Connecticut); Kenneth J. Trotman (Granby, Connecticut) |
| ABSTRACT | A chassis includes top rails extending along a top side of the chassis, bottom rails extending along a bottom side of the chassis, a fluid inlet connected to the chassis that is configured to receive a thermal transfer fluid, and a fluid outlet connected to the chassis that is configured to discharge the thermal transfer fluid. The chassis further includes a thermal transfer fluid path extending between and fluidly coupled to the fluid inlet and the fluid outlet, wherein the thermal transfer fluid is configured to flow through the thermal transfer fluid path, and wherein the thermal transfer fluid path extends in a serpentine pattern through at least one of the top rails and through at least one of the bottom rails. |
| FILED | Monday, June 28, 2021 |
| APPL NO | 17/360839 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 37/34 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 5/0291 (20130101) H05K 7/20272 (20130101) H05K 7/20636 (20130101) H05K 7/20872 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11666221 | O'Brien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Christine O'Brien (Nashville, Tennessee); Katherine Cochran (Nashville, Tennessee); Anita Mahadevan-Jansen (Nashville, Tennessee); Kristen Rose Findley (Nashville, Tennessee); William Stokes (Nashville, Tennessee); Lowell Hays (Nashville, Tennessee); Mohsin Tejani (Nashville, Tennessee); Anne-Marie Crowe (Nashville, Tennessee) |
| ABSTRACT | A method for identification of biochemical markers associated with cervical remodeling over the course of pregnancy of humans includes obtaining Raman signals from the cervix of each of a group of humans with pregnancy at each phase of pregnancy; finding Raman signatures corresponding to each type of cervical tissue from the obtained Raman signals; and identifying biochemical markers associated with cervical remodeling at each phase of pregnancy corresponding to the Raman signatures. |
| FILED | Friday, May 18, 2018 |
| APPL NO | 16/613445 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) Original (OR) Class A61B 5/435 (20130101) A61B 5/6875 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0248 (20130101) G01J 3/2823 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666385 | Feiner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (, None) |
| INVENTOR(S) | Steven Feiner (New York, New York); Gabrielle Loeb (Wynnewood, Pennsylvania); Alon Grinshpoon (New York, New York); Shirin Sadri (San Clemente, California); Carmine Elvezio (Bellmore, New York) |
| ABSTRACT | Certain embodiments include a method for assisting a clinician in performing a medical procedure on a patient using augmented reality guidance. The method can include obtaining a three-dimensional model of an anatomic part of the patient. The method can also include aligning the three-dimensional model with data to form augmented reality guidance for the medical procedure. In addition, the method can include presenting the augmented reality guidance to the clinician during the medical procedure using an augmented reality three-dimensional display. |
| FILED | Thursday, February 20, 2020 |
| APPL NO | 16/796645 |
| ART UNIT | 2173 — Graphical User Interface and Document Processing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 2034/107 (20160201) A61B 2034/108 (20160201) Electric Digital Data Processing G06F 3/167 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 19/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666666 | Pyle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | April D. Pyle (Los Angeles, California); Courtney S. Young (Los Angeles, California); Melissa J. Spencer (Los Angeles, California) |
| ABSTRACT | The present disclosure provides a method of modifying a mutant dystrophin gene in the genome of a cell. The present disclosure further provides compositions and kits for modifying a mutant dystrophin gene in the genome of a cell. |
| FILED | Thursday, February 09, 2017 |
| APPL NO | 16/076616 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0306 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) Original (OR) Class A61K 48/0091 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Peptides C07K 14/4708 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) C12N 15/113 (20130101) C12N 15/861 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666891 | Lou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yang Lou (Tempe, Arizona); Jingyue Liu (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Yang Lou (Tempe, Arizona); Jingyue Liu (Scottsdale, Arizona) |
| ABSTRACT | A nanocatalyst including single atoms of platinum dispersed on a nanoscale metal oxide, and the nanocatalyst comprises 0.01 wt % to 1 wt % platinum. Preparing the nanocatalyst includes combining a solution comprising a nanoscale metal oxide and a compound containing a Group 10 metal to yield a mixture, aging the mixture for a length of time, filtering the mixture to yield a solid, washing the solid to eliminate water soluble anions, and calcining the solid to yield a nanocatalyst including single atoms or clusters of atoms of the Group 10 metal on the nanoscale metal oxide. |
| FILED | Monday, June 06, 2022 |
| APPL NO | 17/833285 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 23/10 (20130101) B01J 23/42 (20130101) Original (OR) Class B01J 23/83 (20130101) B01J 23/745 (20130101) B01J 35/0013 (20130101) B01J 37/06 (20130101) B01J 37/088 (20130101) B01J 37/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11666941 | Claridge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Shelley A Claridge (Lafayette, Indiana); Shi Wah Choong (West Lafayette, Indiana); Jae Jin Bang (West Lafayette, Indiana); Shane Richard Russell (West Lafayette, Indiana) |
| ABSTRACT | This invention discloses a method for controlling nanoscopic wetting near or at a molecular scale for synthetic material applications. In particular this invention relates to a method for preparing a monolayer or thin film with a patterned nanoscopic wetting surface using a ‘sitting’ phase of polymerizable amphiphile, wherein hydrophobic alkyl chains of the amphiphile extend along the supporting surface and the amphiphile molecules align side-to-side, effectively forming a repeating cross-section of bilayer with alternating hydrophilic and hydrophobic stripes of a ˜6 nm pitch tunable based on the chain length of the amphiphile. Products prepared according to the methods disclosed herein are within the scope of this invention. In some embodiments, monolayers or thin films so prepared are transferable. |
| FILED | Monday, October 28, 2019 |
| APPL NO | 16/665320 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/04 (20130101) B05D 1/18 (20130101) B05D 1/204 (20130101) B05D 5/04 (20130101) Original (OR) Class B05D 5/06 (20130101) B05D 5/08 (20130101) B05D 7/24 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 2217/75 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 139/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667301 | Misra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Perceptive Automata, Inc. (Somerville, Massachusetts) |
| ASSIGNEE(S) | Perceptive Automata, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kshitij Misra (Cambridge, Massachusetts); Samuel English Anthony (Cambridge, Massachusetts) |
| ABSTRACT | A system performs modeling and simulation of non-stationary traffic entities for testing and development of modules used in an autonomous vehicle system. The system uses a machine learning based model that predicts hidden context attributes for traffic entities that may be encountered by a vehicle in traffic. The system generates simulation data for testing and development of modules that help navigate autonomous vehicles. The generated simulation data may be image or video data including representations of traffic entities, for example, pedestrians, bicyclists, and other vehicles. The system may generate simulation data using generative adversarial neural networks. |
| FILED | Tuesday, December 10, 2019 |
| APPL NO | 16/709788 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 40/04 (20130101) B60W 50/0097 (20130101) Original (OR) Class B60W 60/0011 (20200201) B60W 60/0015 (20200201) B60W 2554/00 (20200201) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 2201/0213 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Image or Video Recognition or Understanding G06V 20/56 (20220101) Traffic Control Systems G08G 1/0125 (20130101) G08G 1/0145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667535 | Turner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Christopher L. Turner (Lancaster, California); Richard B. Kaner (Pacific Palisades, California); Georgiy Akopov (Ames, Iowa); Michael T. Yeung (Los Angeles, California) |
| ABSTRACT | Disclosed herein are compounds, methods, and tools which comprise tungsten borides and mixed transition metal borides. |
| FILED | Wednesday, November 07, 2018 |
| APPL NO | 16/183346 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/04 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/77 (20130101) C01P 2002/88 (20130101) C01P 2004/03 (20130101) Alloys C22C 1/051 (20130101) C22C 29/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667550 | Westerhoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul K. Westerhoff (Scottsdale, Arizona); Francois Perreault (Tempe, Arizona); Sergio Garcia-Segura (Tempe, Arizona); Shahnawaz Sinha (Chandler, Arizona); Ana Barrios (Tempe, Arizona); Renato Martin Montenegro Ayo (Lima, Peru) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Paul K. Westerhoff (Scottsdale, Arizona); Francois Perreault (Tempe, Arizona); Sergio Garcia-Segura (Tempe, Arizona); Shahnawaz Sinha (Chandler, Arizona); Ana Barrios (Tempe, Arizona); Renato Martin Montenegro Ayo (Lima, Peru) |
| ABSTRACT | A water-disinfecting apparatus includes a vessel with a cathode, an insert with a photoanode, an ultraviolet light source configured to be positioned in the insert, and a power source. The cathode forms an electrically conductive layer on an inner surface of the vessel. The photoanode is configured to be positioned in the cathode. The power source is configured to be operably coupled to the cathode, the photoanode, and the light source. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/245640 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Travelling or Camp Equipment: Sacks or Packs Carried on the Body A45F 3/18 (20130101) A45F 2003/003 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/325 (20130101) C02F 1/4672 (20130101) C02F 1/46109 (20130101) Original (OR) Class C02F 2001/46142 (20130101) C02F 2001/46171 (20130101) C02F 2201/009 (20130101) C02F 2303/04 (20130101) C02F 2305/10 (20130101) C02F 2305/023 (20130101) C02F 2307/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667581 | Cui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures, Inc. (Lincoln, Nebraska) |
| INVENTOR(S) | Bai Cui (Lincoln, Nebraska); Fei Wang (Lincoln, Nebraska); Yongfeng Lu (Lincoln, Nebraska); Michael Nastasi (Lincoln, Nebraska) |
| ABSTRACT | Systems for and methods for improving mechanical properties of ceramic material are provided. The system comprises a heat source for heating the ceramic material to a temperature greater than a brittle-to-ductile transition temperature of the ceramic material; a probe for mounting the ceramic material and configured to extend the ceramic material into the heat source; a plasma-confining medium and a sacrificial layer disposed between the ceramic material and the plasma-confining medium; and an energy pulse generator such as a laser pulse generator. The sacrificial layer is utilized to form plasma between the ceramic material and the plasma-confining medium. The method comprises heating ceramic material to a temperature greater than a brittle-to-ductile transition temperature of the ceramic material and subjecting the ceramic material to energy pulses via a sacrificial layer and a plasma-confining medium whereby a plasma of the sacrificial coating forms between the ceramic material and a plasma-confining medium. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 16/557698 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/53 (20151001) B23K 26/083 (20130101) B23K 26/356 (20151001) B23K 26/0622 (20151001) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 11/005 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/00 (20130101) C04B 35/10 (20130101) C04B 41/009 (20130101) C04B 41/0036 (20130101) C04B 41/0036 (20130101) C04B 41/0072 (20130101) Original (OR) Class C04B 41/0072 (20130101) C04B 41/4527 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667593 | Dos Santos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Nikolas Ramos Dos Santos (Tallahassee, Florida); Igor Alabugin (Tallahassee, Florida); Alexandria Palazzo (Tallahassee, Florida) |
| ABSTRACT | Methods of forming arenes, including asymmetrical arenes, such as asymmetrical pyrene derivatives. Substituents of starting materials may be selected to direct a photochemical cascade and possibly a 1,2-aryl shift. The methods may include a Mallory cyclization, which is controlled, at least in part, by substituents of the starting materials. Compounds and compositions including asymmetrical arenes. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/903529 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 5/393 (20130101) C07C 6/04 (20130101) Original (OR) Class C07C 15/38 (20130101) C07C 2603/50 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667898 | Cegelski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Lynette Cegelski (Palo Alto, California); Wiriya Thongsomboon (Stanford, California) |
| ABSTRACT | Phosphoethanolamine cellulose and methods of making and using it are disclosed. In particular, the invention relates to a method of producing a phosphoethanolamine cellulose biosynthetically using a BcsG phosphoethanolamine transferase for cellulose modification. Recombinant constructs encoding BcsG are described, including constructs encoding BcsG by itself or in combination with BcsE and BcsF, which increase the extent of cellulose modification and the amount of modified cellulose produced. Production of phosphoethanolamine cellulose in cell culture and derivatization of phosphoethanolamine cellulose are also described. |
| FILED | Wednesday, May 05, 2021 |
| APPL NO | 17/308724 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/245 (20130101) C07K 14/255 (20130101) Polysaccharides; Derivatives Thereof C08B 3/06 (20130101) C08B 5/02 (20130101) C08B 5/14 (20130101) C08B 11/08 (20130101) C08B 15/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/10 (20130101) Original (OR) Class C12N 9/14 (20130101) C12N 9/1229 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) Enzymes C12Y 201/01103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667900 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yingxiao Wang (San Diego, California); Shu Chien (La Jolla, California); Lei Lei (San Diego, California); Shaoying Lu (San Diego, California); Jie Sun (San Diego, California) |
| ABSTRACT | Provided are Shp2- and Spleen tyrosine kinase (Syk)-integrated sensing and actuating protein (iSNAP) (Shp2- and Syk-iSNAP) chimeric proteins comprising: a bi-phosphorylatable peptide, optionally a bisphosphoryl tyrosine-based activation (BTAM) motif; a Fluorescent Protein (FP) Förster Resonance Energy Transfer (FRET) (or FP FRET) pair or pair of motifs; a truncated Shp2 domain comprising an N-Src Homology 2(N-SH2) domain and a C-Src Homology 2(C-SH2) domain; and, a phosphatase (PTP) domain or a kinase domain. Provided are engineered cells and methods for cancer cell or tumor eradication, or for the treatment or amelioration of a cancer, tumor or dysfunctional cell, or for promoting an anti-cancer, anti-tumor or anti-dysfunctional cell inflammatory response, including enhancing macrophage-, monocyte-, microglia-, osteoclast-, Kupffer cell- or dendritic cell-mediated antibody- or monoclonal antibody (mAb)-guided cancer or dysfunctional cell or tumor eradication, amelioration, or treatment. |
| FILED | Thursday, July 12, 2018 |
| APPL NO | 16/631041 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/39558 (20130101) Peptides C07K 14/435 (20130101) C07K 2319/03 (20130101) C07K 2319/61 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/03048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667970 | Bashir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Rashid Bashir (Champaign, Illinois); Anurup Ganguli (Champaign, Illinois); Farhad Kosari (Rochester, Minnesota) |
| ABSTRACT | Various methods and devices for spatial molecular analysis from tissue is provided. For example, a method of spatially mapping a tissue sample is provided with a microarray having a plurality of wells, wherein adjacent wells are separated by a shearing surface; overlaying said microarray with a tissue sample; applying a deformable substrate to an upper surface of said tissue sample; applying a force to the deformable substrate, thereby forcing underlying tissue sample into the plurality of wells; shearing the tissue sample along the shearing surface into a plurality of tissue sample islands, with each unique tissue sample island positioned in a unique well; and imaging or quantifying said plurality of tissue sample islands, thereby generating a spatial map of said tissue sample. The imaging and/or quantifying may use a nucleic acid amplification technique. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/939665 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/5085 (20130101) B01L 3/50851 (20130101) B01L 2200/0642 (20130101) B01L 2300/0819 (20130101) B01L 2300/0858 (20130101) B01L 2300/0893 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1003 (20130101) C12N 15/1003 (20130101) C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6827 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2521/107 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) G01N 2001/282 (20130101) G01N 2001/2873 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 25/10 (20190201) G16B 30/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668497 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Nanfang Yu (Fort Lee, New Jersey); Jyotirmoy Mandal (New York, New York); Adam Overvig (New York, New York); Norman Nan Shi (San Jose, California); Meng Tian (Fort Lee, New Jersey) |
| ABSTRACT | Systems and methods for radiative cooling and heating are provided. For example, systems for radiative cooling can include a top layer including one or more polymers, where the top layer has high emissivity in at least a portion of the thermal spectrum and an electromagnetic extinction coefficient of approximately zero, absorptivity of approximately zero, and high transmittance in at least a portion of the solar spectrum, and further include a reflective layer including one or more metals, where the reflective layer has high reflectivity in at least a portion of the solar spectrum. |
| FILED | Monday, March 21, 2022 |
| APPL NO | 17/699789 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/18 (20130101) B32B 27/283 (20130101) B32B 33/00 (20130101) B32B 2305/18 (20130101) B32B 2305/30 (20130101) B32B 2307/30 (20130101) B32B 2307/416 (20130101) B32B 2311/24 (20130101) B32B 2333/12 (20130101) B32B 2383/00 (20130101) B32B 2386/00 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 10/40 (20180501) F24S 70/30 (20180501) F24S 70/60 (20180501) F24S 70/225 (20180501) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/003 (20130101) Original (OR) Class Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 2245/06 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668638 | Sulchek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Todd Sulchek (Atlanta, Georgia); Alexander Alexeev (Atlanta, Georgia); Bushra Tasadduq (Atlanta, Georgia) |
| ABSTRACT | A microchannel for processing cells by compression of the cells including an inlet, ridges and an outlet. Each ridge including a compressive surface and a cell adhesion entity. The outlet configured to remove at least one of a first portion of the cells and a second portion of the cells from the microchannel. Each ridge oriented at an angle of from 25 degrees to 70 degrees relative to a center axis of the microchannel. The cell adhesion entity configured such that the first portion of the cells has a first adhesion property relative to the cell adhesion entity to follow a first trajectory through the microchannel. The cell adhesion entity further configured such that the second portion of the cells has a second adhesion property relative to the cell adhesion entity to follow a second trajectory through the microchannel. The first trajectory is different from the second trajectory. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/650033 |
| ART UNIT | 1677 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 3/502776 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2300/16 (20130101) B01L 2300/0877 (20130101) B01L 2400/086 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 15/1056 (20130101) Original (OR) Class G01N 33/5005 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668676 | Yanik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ahmet Ali Yanik (Santa Cruz, California); Xiangchao Zhu (Santa Cruz, California); Evan Peterson (Sebastopol, California); Yixiang Li (Santa Cruz, California) |
| ABSTRACT | The present disclosure provides methods, microfluidic devices, and systems for isolating target particles from a sample containing or suspected of containing the target particles. The methods, microfluidic devices, and systems disclosed herein facilitate affinity-based isolation of target particles in a microfluidic channel by translating the target particles to the side walls of the microfluidic channel where capture agents that bind to the target particles are immobilized. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 16/886438 |
| ART UNIT | 1677 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/022 (20130101) Original (OR) Class G01N 29/046 (20130101) G01N 29/2437 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11668711 — Multiplexed diagnostic assay for iron and vitamin A deficiency and methods of use thereof
| US 11668711 | Mehta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERISTY (Ithaca, New York) |
| INVENTOR(S) | Saurabh Mehta (Ithaca, New York); David Erickson (Ithaca, New York); Zhengda Lu (Ithaca, New York) |
| ABSTRACT | A diagnostic assay strip includes a first layer that includes an iron mobile labelled specific binding partner that will bind to and iron biomarker from a sample and produce an iron complex and a vitamin A mobile labelled specific binding partner that will bind to a vitamin A biomarker from the sample and produce a vitamin A complex. A second layer includes iron and vitamin A test regions, and a control region. The iron test region has immobilized specific binding partners that will bind to the iron complex. The vitamin A test region has immobilized vitamin A biomarker that will bind to vitamin A mobile labelled specific binding partner, which is not bound to the vitamin A biomarker, passing from the first layer to the second layer. The control region has a moiety which will non-specifically bind to and immobilize the iron and vitamin A labelled specific binding partners. Methods of using the diagnostic assay strip are also discussed. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/763707 |
| ART UNIT | 1677 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/82 (20130101) G01N 33/84 (20130101) G01N 33/582 (20130101) G01N 33/6803 (20130101) G01N 33/54386 (20130101) G01N 33/54388 (20210801) Original (OR) Class G01N 2021/6441 (20130101) G01N 2333/705 (20130101) G01N 2333/4737 (20130101) G01N 2458/00 (20130101) G01N 2470/04 (20210801) G01N 2470/10 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668719 | Jarrold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | The Trustees Of Indiana University (Bloomington, Indiana) |
| INVENTOR(S) | Martin F. Jarrold (Bloomington, Indiana); Corrine A. Lutomski (Bloomington, Indiana) |
| ABSTRACT | The present disclosure relates to a method of identifying components present in a lipoprotein. Methods provided include single particle mass spectrometry, such as charge detection mass spectrometry (CDMS). Distinct subpopulations that exist within lipoprotein classes are determined by correlating m/z and mass. |
| FILED | Thursday, September 20, 2018 |
| APPL NO | 16/647955 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/6848 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/025 (20130101) H01J 49/40 (20130101) H01J 49/0068 (20130101) H01J 49/4225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668803 | Sampson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Rachel Sampson (Oviedo, Florida); Alireza Fardoost (Orlando, Florida); Guifang Li (Orlando, Florida); He Wen (Oviedo, Florida); Yuanhang Zhang (Orlando, Florida); Huiyuan Liu (Orlando, Florida) |
| ABSTRACT | A few-mode light detection and ranging (LIDAR) system may include an illumination source to generate an illumination beam, one or more transmission optics to direct at least a portion of the illumination beam within a field of view, one or more collection optics to collect return light from an object in the field of view illuminated by the illumination beam, wherein the collected return light includes a plurality of spatial modes, a few-mode optical amplifier to optically amplify portions of the return light propagating along at least two of the plurality of spatial modes, and a detector configured to convert output light from the few-mode optical amplifier to an output electrical signal. |
| FILED | Thursday, August 22, 2019 |
| APPL NO | 16/548644 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) Original (OR) Class G01S 7/4814 (20130101) G01S 7/4817 (20130101) G01S 17/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11669009 | Sreenivasan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Sidlgata V. Sreenivasan (Austin, Texas); Shrawan Singhal (Austin, Texas); Ovadia Abed (Austin, Texas); Lawrence Dunn (Austin, Texas); Paras Ajay (Austin, Texas); Ofodike Ezekoye (Austin, Texas) |
| ABSTRACT | A method for fabricating patterns on a flexible substrate in a roll-to-roll configuration. Drops of a monomer diluted in a solvent are dispensed on a substrate, where the drops spontaneously spread and merge with one another to form a liquid resist formulation. The solvent is evaporated (e.g., blanket evaporation) from the liquid resist formulation followed by selective multi-component resist film evaporation resulting in a non-uniform and substantially continuous film on the substrate. The gap between the film on the substrate and a template is closed such that the film fills the features of the template. After cross-linking the film to polymerize the film, the template is separated from the substrate thereby leaving the polymerized film on the substrate. |
| FILED | Thursday, August 03, 2017 |
| APPL NO | 16/322842 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/24 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670441 | Carpenter |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Virginia Commonwealth University (Richmond, Virginia) |
| ASSIGNEE(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| INVENTOR(S) | Everett E. Carpenter (Mechanicsville, Virginia) |
| ABSTRACT | In various aspects, methods of making perovskite manganese oxide particles are provided as well as perovskite manganese oxide particles made therefrom. The perovskite manganese oxide particles exhibit a strong magnetocaloric effect, making them well suited for applications in power generation and magnetic refrigeration, especially at or near room temperature. The methods can include forming an aqueous mixture of (i) a low-molecular-weight polymeric polyalcohol gel precursor, (ii) a stoichiometric amount of metal salts or hydrates thereof, wherein the metal salts or hydrates thereof comprise at least a Manganese (Mn), and (iii) a polybasic carboxylic acid; polymerizing the aqueous mixture to form a gel containing perovskite manganese oxide nanoparticles entrapped therein; and calcining the gel to remove at least a portion of organic material in the gel and form the perovskite manganese oxide particles. Method and systems are also provided for power generation and magnetic refrigeration using the perovskite manganese oxide particles. |
| FILED | Saturday, December 01, 2018 |
| APPL NO | 16/768173 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) F25B 2321/002 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/012 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11671100 | Bhunia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Swarup Bhunia (Gainesville, Florida); Christopher Vega (Gainesville, Florida); Shubhra Deb Paul (Gainesville, Florida) |
| ABSTRACT | Methods and systems are directed to creating a physical unclonable function (PUF) on a Field Programmable Gate Array (FPGA) and generating a unique signature for a device. The method includes, in part, designing a PUF by taking advantages of programmable logic elements on the FPGA, and extracting uninitialized values associated with one or more storage elements comprised in the PUF when the FPGA is powered up. The extracted uninitialized values can be combined to generate the unique signature for the device. The one or more storage elements can be bi-stable memory cells that are mapped to look up tables (LUTs) on the FPGA. The coordinates of these LUTs can be determined based on hamming distance analysis. Alternatively, the one or more storage elements can be memory cells associated with boundary scan cells of a boundary scan chain. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/465958 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 19/1737 (20130101) H03K 19/1776 (20130101) Original (OR) Class H03K 19/17728 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11667795 | Van Overmeere et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Quentin Van Overmeere (Mountain View, California); Scott Alan Elrod (Palo Alto, California); Scott E. Solberg (San Jose, California); Gabriel Iftime (Dublin, California); Ravi Neelakantan (Redwood City, California); Bernard D. Casse (Saratoga, California) |
| ABSTRACT | Disclosed herein in is a radiative cooling formulation including a first component with >55% reflectance in a wavelengths range of 0.3 to 2.5 microns, a second component with a first thermal emissivity peak value greater than 0.85 at a first wavelength in a range of 8 to 13 microns (μm), and a third component to mechanically bind together a mixture of the first component and second component. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/392028 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/30 (20130101) C08K 2003/2241 (20130101) C08K 2003/3045 (20130101) C08K 2201/005 (20130101) Compositions of Macromolecular Compounds C08L 33/10 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/004 (20130101) Original (OR) Class C09D 5/024 (20130101) C09D 7/69 (20180101) C09D 129/14 (20130101) C09D 129/14 (20130101) C09D 133/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667853 | Marker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gas Technology Institute (Des Plaines, Illinois) |
| ASSIGNEE(S) | GTI Energy (Des Plaines, Illinois) |
| INVENTOR(S) | Terry Marker (Park Ridge, Illinois); Martin B. Linck (Wilmette, Illinois); Jim Wangerow (Oak Park, Illinois); Pedro Ortiz-Toral (Wheeling, Illinois) |
| ABSTRACT | Processes for converting methane and/or other hydrocarbons to synthesis gas (i.e., a gaseous mixture comprising H2 and CO) are disclosed, in which at least a portion of the hydrocarbon(s) is reacted with CO2. At least a second portion of the methane may be reacted with H2O (steam), thereby improving overall thermodynamics of the process, in terms of reducing endothermicity (ΔH) and the required energy input, compared to “pure” dry reforming in which no H2O is present. Such dry reforming (reaction with CO2 only) or CO2-steam reforming (reaction with both CO2 and steam) processes are advantageously integrated with Fischer-Tropsch synthesis to yield liquid hydrocarbon fuels. Further integration may involve the use of a downstream finishing stage involving hydroisomerization to remove FT wax. Yet other integration options involve the use of combined CO2-steam reforming and FT synthesis stages (optionally with finishing) for producing liquid fuels from gas streams generated in a number of possible processes, including the hydropyrolysis of biomass. |
| FILED | Tuesday, July 14, 2020 |
| APPL NO | 16/928096 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 3/06 (20130101) B01D 3/143 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/50 (20170801) Acyclic or Carbocyclic Compounds C07C 1/04 (20130101) C07C 1/12 (20130101) C07C 5/13 (20130101) C07C 9/04 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 47/32 (20130101) C10G 50/00 (20130101) Original (OR) Class C10G 2300/1025 (20130101) C10G 2400/02 (20130101) C10G 2400/04 (20130101) C10G 2400/08 (20130101) C10G 2400/16 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667995 | Godlewski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ford Global Technologies, LLC (Dearborn, Michigan); The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | Ford Global Technologies, LLC (Dearborn, Michigan); The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Larry Alan Godlewski (Fenton, Michigan); Mei Li (Bloomfield Hills, Michigan); Carlos Engler-Pinto (Dearborn, Michigan); Simon Naymovich Lekakh (Columbia, Missouri) |
| ABSTRACT | A cast iron alloy is provided with a composition in weight percent (wt. %) of carbon between 2.6 to 3.4 wt. %, silicon between 2.4 to 3.2 wt. %, manganese between 0.3 to 0.6 wt. %, molybdenum between 0.4 to 1.2 wt. %, nickel between 0.6 to 1.75 wt. %, magnesium between 0.01 to 0.075 wt. %, aluminum between 1.8 to 3.5 wt. %, sulfur between 0.003 to 0.025 wt. %, zirconium between 0.001 to 0.02 wt. %, cerium between 0.001 to 0.03 wt. %, lanthanum between 0.0005 to 0.02 wt. %, and a balance of iron and unavoidable trace elements. A part formed from the cast iron alloy is also provided and the part has an Ac1 temperature equal to or greater than 895° C. and a thermo-mechanical fatigue lifetime of at least 10,000 cycles when cycled between 400° C. to 800° C. with a total cyclic strain equal to 0.001 m/m. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 17/448262 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 37/04 (20130101) C22C 37/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667996 | Rios et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); Eck Industries, Inc. (Manitowoc, Wisconsin) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); Eck Industries, Inc. (Manitowoc, Wisconsin) |
| INVENTOR(S) | Orlando Rios (Knoxville, Tennessee); Michael S. Kesler (Knoxville, Tennessee); Zachary C. Sims (Knoxville, Tennessee); Edgar Lara-Curzio (Oak Ridge, Tennessee); David Weiss (Manitowoc, Wisconsin) |
| ABSTRACT | A solid aluminum-fiber composite comprising: (i) an aluminum-containing matrix comprising elemental aluminum; (ii) coated or uncoated fibers embedded within said aluminum-containing matrix, wherein said fibers have a different composition than said aluminum-containing matrix and impart additional strength to said aluminum-containing matrix as compared to said aluminum-containing matrix in the absence of said fibers embedded therein; and (iii) an intermetallic layer present as an interface between each of said fibers and the aluminum-containing matrix, wherein said intermetallic layer has a composition different from said aluminum-containing matrix and said fibers, and said intermetallic layer contains at least one element that is also present in the aluminum-containing matrix and at least one element present in the fibers, whether from the coated or interior portion of the fibers. Methods of producing the above-described composite are also described. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/203881 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Alloys C22C 47/04 (20130101) C22C 47/12 (20130101) C22C 49/06 (20130101) Original (OR) Class C22C 49/12 (20130101) C22C 49/14 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12736 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668012 | Ding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Dong Ding (Idaho Falls, Idaho); Ting He (Idaho Falls, Idaho); Wei Wu (Idaho Falls, Idaho); Yunya Zhang (Idaho Falls, Idaho) |
| ABSTRACT | A method of forming a hydrocarbon product and hydrogen gas comprises introducing CH4 to a positive electrode of an electrochemical cell comprising the positive electrode, a negative electrode, and a proton-conducting membrane between the positive electrode and the negative electrode. The proton-conducting membrane comprises an electrolyte material having an ionic conductivity greater than or equal to about 10−2 S/cm at one or more temperatures within a range of from about 150° C. to about 600° C. A potential difference is applied between the positive electrode and the negative electrode of the electrochemical cell to produce the hydrocarbon product and the hydrogen gas. A CH4 activation system and an electrochemical cell are also described. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196283 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/02 (20130101) C25B 3/00 (20130101) Original (OR) Class C25B 9/19 (20210101) C25B 11/077 (20210101) C25B 11/081 (20210101) C25B 13/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668242 | Griffis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Clay Thomas Griffis (Greenville, South Carolina); Jonathan Dwight Berry (Simpsonville, South Carolina); Keith Cletus Belsom (Laurens, South Carolina); Heath Michael Ostebee (Easley, South Carolina) |
| ABSTRACT | Fuel injection assemblies and combustors are provided. A fuel injection assembly includes a fuel injector having a first annular wall that about an axial centerline and extends from a primary inlet disposed at a first end to a primary outlet disposed at a second end. A second annular wall surrounds the first annular wall. A fuel plenum is defined between the first annular wall and the second annular wall. A fuel duct extends from a fuel outlet defined in the second annular wall to a fuel inlet. wherein the fuel duct is in fluid communication with the fuel plenum. The fuel duct includes a polygonal segment and a cylindrical inlet segment. The polygonal segment extends from the fuel outlet to the cylindrical inlet segment. |
| FILED | Tuesday, September 29, 2020 |
| APPL NO | 17/036745 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/222 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/35 (20130101) F05D 2250/231 (20130101) Burners F23D 14/583 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668478 | Woods et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Jason David Woods (Boulder, Colorado); Eric Kozubal (Superior, Colorado) |
| ABSTRACT | Integrated systems comprising both i) heat and mass exchange systems and ii) electrolysis stacks are disclosed, together with related methods of use. The disclosed systems cool and/or dehumidify air using two streams of salt solutions as liquid desiccants. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/688293 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/1417 (20130101) Original (OR) Class F24F 13/30 (20130101) F24F 2003/1435 (20130101) F24F 2003/1458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668497 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Nanfang Yu (Fort Lee, New Jersey); Jyotirmoy Mandal (New York, New York); Adam Overvig (New York, New York); Norman Nan Shi (San Jose, California); Meng Tian (Fort Lee, New Jersey) |
| ABSTRACT | Systems and methods for radiative cooling and heating are provided. For example, systems for radiative cooling can include a top layer including one or more polymers, where the top layer has high emissivity in at least a portion of the thermal spectrum and an electromagnetic extinction coefficient of approximately zero, absorptivity of approximately zero, and high transmittance in at least a portion of the solar spectrum, and further include a reflective layer including one or more metals, where the reflective layer has high reflectivity in at least a portion of the solar spectrum. |
| FILED | Monday, March 21, 2022 |
| APPL NO | 17/699789 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/18 (20130101) B32B 27/283 (20130101) B32B 33/00 (20130101) B32B 2305/18 (20130101) B32B 2305/30 (20130101) B32B 2307/30 (20130101) B32B 2307/416 (20130101) B32B 2311/24 (20130101) B32B 2333/12 (20130101) B32B 2383/00 (20130101) B32B 2386/00 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 10/40 (20180501) F24S 70/30 (20180501) F24S 70/60 (20180501) F24S 70/225 (20180501) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/003 (20130101) Original (OR) Class Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 2245/06 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668544 | Timpson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Erik Joseph Timpson (Olathe, Kansas); Seth Hartman (Belton, Missouri); Joshua J. Miller (Kansas City, Missouri) |
| ABSTRACT | An EM driver for accelerating an object may be configured as an EM rifle for accelerating, rotating to spin-stabilize, and releasing a projectile. A core includes a stator coil, forward and reverse coils, a railed shaft, and a transfer shaft. The stator coil generates a first EM field, and the forward and reverse coils generate second and third EM fields which interact with the first EM field to accelerate the armature in forward and reverse directions, respectively. The railed shaft is elongated along a central axis through the armature and includes multiple rails arranged helically around a central shaft. The armature remains in contact with the rails during acceleration so as to impart a turning motion. The transfer shaft is physically coupled with and projects forwardly from the armature and transfers to the projectile the acceleration and the turning motion of the armature in the forward direction. |
| FILED | Friday, February 26, 2021 |
| APPL NO | 17/186082 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for F41B 6/003 (20130101) Original (OR) Class F41B 6/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668595 | Holland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Justin M. Holland (Clinton, Tennessee); Deandra J. Peoples (Nashville, Tennessee); Stephen R. Bennett (Rockwood, Tennessee); Benjamin D. Green (Knoxville, Tennessee) |
| ABSTRACT | A fluid level and conductivity sensor having a sensing probe with four electrodes disposed therein particularly suited for high temperature applications. A distal end of the second and third electrodes are positioned a distance from the sensing end that is greater than distal ends of the first and fourth electrodes. The sensor includes an electronics system having a signal relay system for receiving signals from each of the electrodes and switching between different measurement modes by determining a resistance between selected pairs of electrodes based on instructions from the microcontroller. The measurement modes include a conductivity measurement mode in which a resistance between the first and fourth electrodes is determined, and a fluid level measurement mode in which a resistance between the first and third electrodes is determined and compared to a resistance between the second and third electrodes. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/471589 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/241 (20130101) Original (OR) Class G01F 23/242 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11668618 — Apparatus for measuring the pressure and flow rate of a high temperature corrosive liquid
| US 11668618 | Parish et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Flowserve Management Company (Irving, Texas) |
| ASSIGNEE(S) | Flowserve Pte. Ltd. (Singapore, Singapore) |
| INVENTOR(S) | Paul Jeffrey Parish (Spanish Fork, Utah); Michael P. Nelson (Lehi, Utah) |
| ABSTRACT | An apparatus for measuring a pressure of a corrosive or high temperature process liquid includes a pressure sensor in communication with the process liquid via a vertical tube. A buffer gas injected into the vertical tube forms a liquid/gas interface at a desired height. The buffer gas supply is then either isolated or regulated so as to cause the buffer gas pressure within the vertical tube to remain equal with the process liquid pressure. The pressure sensor indirectly measures the process liquid pressure by measuring the buffer gas pressure within the vertical tube, while remaining chemically and thermally protected from the process liquid. In embodiments, pressure measurements from a pair of gas buffered pressure sensors located upstream and downstream of a valve are combined with measurements of the process liquid temperature to determine a flow rate of the process liquid through the valve. |
| FILED | Monday, September 27, 2021 |
| APPL NO | 17/485670 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/34 (20130101) G01F 1/68 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 7/18 (20130101) G01L 19/0627 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668845 | Preston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jeffrey Robert Preston (Knoxville, Tennessee); Ashley C. Stowe (Knoxville, Tennessee) |
| ABSTRACT | A wide band gap semiconductor NAND based neutron detection system includes a semiconductor layer comprising a wide band gap material with a neutron absorber material in the wide band gap material, and the semiconductor layer is the only layer of the wide band gap semiconductor NAND based neutron detection system fabricated with the neutron absorber material. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 17/370366 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/245 (20130101) Original (OR) Class G01T 3/08 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11669959 | Schiefelbein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Bryan E. Schiefelbein (Kansas City, Missouri); Christopher Alan Griffiths (Kansas City, Missouri) |
| ABSTRACT | Systems, methods, and computer-readable media for evaluating a set of computed tomography data associated with a lattice structure. The lattice structure may be additively manufactured. The computed tomography data may be segmented using a filter for identifying blob-like structures to identify nodes present within the lattice structure. A three-dimensional path traversal is applied to volumetric data to identify a plurality of struts within the lattice structure that are compared to corresponding struts within a set if three-dimensional mesh data of the lattice structure to identify defective struts. Further, two-dimensional slices may be extracted from each of the computed tomography data and the mesh data and compared to identify one or more inconsistencies indicative of defects within the lattice structure. |
| FILED | Thursday, April 14, 2022 |
| APPL NO | 17/720875 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/4038 (20130101) G06T 7/001 (20130101) Original (OR) Class G06T 2200/24 (20130101) G06T 2207/10081 (20130101) G06T 2207/20044 (20130101) G06T 2207/20092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670036 | Paglieroni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | David W. Paglieroni (Pleasanton, California); Harry E. Martz, Jr. (Livermore, California) |
| ABSTRACT | An automatic threat recognition system and method is disclosed for scanning the x-ray CT image of an article to identify the objects of interest (OOIs) contained within the article, which are otherwise not always quickly apparent or discernable to an individual. The system uses a computer to receive information from two-dimensional (2D) image slices from a reconstructed computed tomography (CT) scan image and to produce a plurality of voxels for each slice of the 2D image. The computer analyzes the voxels to create a likelihood map (LM) representing likelihoods that voxels making up the CT image are associated with a material of interest (MOI). The computer further analyzes the LM to construct neighborhoods of voxels within the LM, and classifies each voxel neighborhood based on its features, thereby decluttering the LM to facilitate the process of connecting voxels of a like MOI together to form segments. The computer classifies each candidate segment based on its features, thereby identifying those segments that correspond to objects of interest. |
| FILED | Tuesday, July 14, 2020 |
| APPL NO | 16/928653 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) G06K 9/6267 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 15/005 (20130101) G06T 15/08 (20130101) Original (OR) Class G06T 2207/10081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670797 | Pol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Vilas Ganpat Pol (West Lafayette, Indiana); Patrick J H Kim (West Lafayette, Indiana) |
| ABSTRACT | A metal-ion deposition regulator to regulate the flux and deposition of metal ions in an electrochemical cell. The regulator containing two membranes made of a polymer and a plurality of two-dimensional porous nanosheets sandwiched between the two membranes. The regulator is capable of distributing flux of metal ions passing through the metal-ion deposition regulator and regulating the deposition of the metal ions onto the cathode or anode thereby suppressing dendrite growth in the electrochemical cell. An electrochemical cell containing an anode, a cathode, a liquid electrolyte, and a metal-ion deposition regulator. A method of making a metal-ion deposition regulator. The method includes fabricating two-dimensional porous nanosheets utilizing graphene oxide as an expendable template, and sandwiching the porous nanosheets between two membranes made of a polymer such that the nanosheets are in contact with the two membranes. |
| FILED | Thursday, December 20, 2018 |
| APPL NO | 16/228498 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) Original (OR) Class H01M 50/44 (20210101) H01M 50/46 (20210101) H01M 50/414 (20210101) H01M 50/417 (20210101) H01M 50/426 (20210101) H01M 50/434 (20210101) H01M 50/446 (20210101) H01M 50/451 (20210101) H01M 50/457 (20210101) H01M 50/489 (20210101) H01M 50/491 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670881 | Khaligh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); Fariborz Musavi (Redmond, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Alireza Khaligh (Arlington, Virginia); Fariborz Musavi (Redmond, Washington) |
| ABSTRACT | In some embodiments, systems and methods for connector assembly for use with an AC or DC power interface of a power conversion device, such as a converter and an inverter, are provided. The connector assembly can include a circuit board, a power connector, and a pin. The power connector can have a base configured to be secured relative to the circuit board and define a first channel extending through the power connector along a first channel axis. The first pin can have a first pin body that extends along a first pin axis and a first connection element that extends along the first pin axis from the first pin body to a first terminal end that is skewed relative to the first pin axis. |
| FILED | Monday, November 02, 2020 |
| APPL NO | 17/087343 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/7082 (20130101) Original (OR) Class H01R 13/2471 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/32 (20141201) H02S 40/36 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670933 | Shen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zheng John Shen (Chicago, Illinois); Yuanfeng Zhou (Chicago, Illinois); Risha Na (Chicago, Illinois) |
| ASSIGNEE(S) | ILLINOIS INSTITUTE OF TECHNOLOGY (Chicago, Illinois) |
| INVENTOR(S) | Zheng John Shen (Chicago, Illinois); Yuanfeng Zhou (Chicago, Illinois); Risha Na (Chicago, Illinois) |
| ABSTRACT | A momentary circuit interrupter in series connection with a mechanical switch to provide protection against short circuit faults in a DC power circuit. The momentary circuit interrupter injects a transient voltage pulse via a pulse transformer to reduce a DC fault current to near zero in a DC circuit branch, thus allowing the mechanical switch to disconnect the faulty branch under a near zero-current condition. The power electronic circuit on the primary side of the transformer controls the discharge of a plurality of pre-charged capacitors to generate the transient voltage pulse during the fault interruption process, but otherwise does not incur any power loss during normal operation. The secondary winding of the pulse transformer conducts the main DC current, and is highly conductive to minimize the conduction power loss. The invention provides ultrafast response to a short circuit fault (even faster than solid-state circuit breakers and much faster than hybrid circuit breakers), significantly reduced overcurrent stress in the power system, and/or ultralow conduction power losses. |
| FILED | Thursday, October 14, 2021 |
| APPL NO | 17/501175 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 33/596 (20130101) Emergency Protective Circuit Arrangements H02H 1/0007 (20130101) H02H 3/087 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11671054 | Brocato et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Robert W. Brocato (Sandia Park, New Mexico); Michael P. Frank (Albuquerque, New Mexico) |
| ABSTRACT | An adiabatic resonator, an adiabatic oscillator, and an adiabatic oscillator system are disclosed. An adiabatic system is one that ideally transfers no heat outside of the system, thereby reducing the required operating power. The adiabatic resonator, which includes a plurality of tank circuits, acts as an energy reservoir, the missing aspect of previously attempted adiabatic computational systems. By using the adiabatic resonator as a feedback element with an amplifier, an adiabatic oscillator is formed. An adiabatic oscillator system is formed with a primary adiabatic oscillator feeding a plurality of secondary adiabatic oscillators. In this manner, the adiabatic oscillator system may be used to generate the multiple clock signals required of adiabatic computational logic elements, such as Split-level Charge Recovery Logic and 2-Level Adiabatic Logic. The adiabatic oscillator system stores enough energy to drive many individual adiabatic computational logic elements, permitting implementation of complex logic circuits. |
| FILED | Thursday, August 19, 2021 |
| APPL NO | 17/406240 |
| ART UNIT | 2849 — Electrical Circuits and Systems |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/12 (20130101) Original (OR) Class Amplifiers H03F 3/2176 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11671320 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jared M. Smith (Knoxville, Tennessee); Jordan A. Johnson (Knoxville, Tennessee); Brian Weber (Alexandria, Virginia); Christopher R. Hathhorn (Knoxville, Tennessee); Benjamin T. McDaniel (Deer Park, New York) |
| ABSTRACT | One or more virtual supervisory control and data acquisition (SCADA) controllers are provided. The virtual SCADA controller(s) may be deployed upon a detection of a failure of a physical SCADA controller. An on-site module may detect failure including a security breach which causes the physical SCADA controller to be disconnected from a network and the virtual SCADA controller(s) to take over control. The virtual SCADA controller(s) may be on-site or off-site. |
| FILED | Thursday, October 21, 2021 |
| APPL NO | 17/506969 |
| ART UNIT | 2447 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/082 (20130101) H04L 41/0668 (20130101) H04L 41/0695 (20130101) H04L 41/0816 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11666080 | Kozubal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| INVENTOR(S) | Mark A. Kozubal (Bozeman, Montana); Richard E. Macur (Manhattan, Montana); Yuval C. Avniel (Missoula, Montana); Maximilian Devane Hamilton (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Friday, August 05, 2022 |
| APPL NO | 17/882490 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667682 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fuzhong Zhang (St. Louis, Missouri); Christopher H. Bowen (St. Louis, Missouri); Bin Dai (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Fuzhong Zhang (St. Louis, Missouri); Christopher H. Bowen (St. Louis, Missouri); Bin Dai (St. Louis, Missouri) |
| ABSTRACT | The present disclosure is directed to systems and methods for synthesizing a spidroin. In some embodiments, the methods comprise synthesizing a monomer in vivo in a heterologous host, the monomer comprising an N-terminus IntC domain and a C-terminus IntN domain, and post-translationally polymerizing the synthesized monomer via in vitro split-intein mediated polymerization. |
| FILED | Friday, December 13, 2019 |
| APPL NO | 16/713643 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/05 (20190201) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2089/00 (20130101) B29K 2995/0088 (20130101) Peptides C07K 14/43518 (20130101) Original (OR) Class C07K 2319/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 15/70 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/02 (20130101) D01D 5/06 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668633 | King et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Arlington, Virginia) |
| INVENTOR(S) | Garnel King (Madison, Alabama); Dennis L. Coad (Madison, Alabama); Jennifer L. Chevallier (Huntsville, Alabama) |
| ABSTRACT | The present disclosure provides an apparatus and method of use thereof for compressive creep testing of materials in the presence of fluids. The apparatus includes a cantilever arm connected on a first end to a cantilever pivot and including a weight holder on a second end; a first platen connected to the cantilever arm via a swivel located between the first end and the second end; a reservoir; and a second platen disposed within the reservoir and positioned to secure a sample between the first platen and the second platen when a force is applied via the weight holder and the first platen to a sample. Electrical properties of the material can be monitored and measured during the compression creep testing. |
| FILED | Tuesday, April 21, 2020 |
| APPL NO | 16/854537 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/04 (20130101) G01N 3/14 (20130101) Original (OR) Class G01N 2203/0019 (20130101) G01N 2203/0071 (20130101) G01N 2203/0242 (20130101) G01N 2203/0617 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668896 | Brennan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eagle Technology, LLC (Melbourne, Florida) |
| ASSIGNEE(S) | EAGLE TECHNOLOGY, INC. (Melbourne, Florida) |
| INVENTOR(S) | Sean A. Brennan (Pittsford, New York); Matthew John East (Fairport, New York) |
| ABSTRACT | According to one implementation a mount pad is provided that includes a plurality of arcuate flexure members disposed between and connected to top and bottom plates. According to some implementations a majority or all of the arcuate flexure members have a semi-circular cross-section and are arranged to form a plurality of radially spaced-apart concentric rings. Concave surfaces of the arcuate flexure members face radially inward toward a center of the concentric rings. Circumferential adjacent arcuate flexure members in each of the concentric rings are circumferentially spaced apart from one another so that a gap exists between them. According to some implementations the mount pad further includes a coupling unit prolonging from one of the top and bottom plates, the coupling unit facilitating a connection of the mount pad to a support structure. According to some implementations the mount pad is a monolithic structure. According to some implementations the monolithic structure is made using an additive manufacturing method. |
| FILED | Thursday, March 11, 2021 |
| APPL NO | 17/198699 |
| ART UNIT | 3632 — Static Structures, Supports and Furniture |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 7/182 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670432 | Choi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Sang H. Choi (Poquoson, Virginia); Dennis M. Bushnell (Hampton, Virginia); David R. Komar (Hampton, Virginia); Robert C. Hendricks (Cleveland, Ohio) |
| ABSTRACT | The present disclosure is directed to a nuclear thermionic avalanche cell (NTAC) systems and related methods of generating energy comprising a radioisotope core, a plurality of thin-layered radioisotope sources configured to emit high energy beta particles and high energy photons, and a plurality of NTAC layers integrated with the radioisotope core and the radioisotope sources, wherein the plurality of NTAC layers are configured to receive the beta particles and the photons from the radioisotope core and sources, and by the received beta particles and photons, free up electrons in an avalanche process from deep and intra bands of an atom to output a high density avalanche cell thermal energy through a photo-ionic or thermionic process of the freed up electrons. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/571765 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Conversion of Chemical Elements; Radioactive Sources G21G 1/12 (20130101) G21G 2001/0068 (20130101) G21G 2001/0094 (20130101) Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 1/04 (20130101) Original (OR) Class G21H 1/12 (20130101) G21H 1/103 (20130101) G21H 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670903 | Delavaux et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cybel, LLC. (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Cybel, LLC. (Bethlehem, Pennsylvania) |
| INVENTOR(S) | Jean-Marc Delavaux (Pittstown, New Jersey); Robert E. Tench (Allentown, Pennsylvania); Alexandre Amavigan (Whitehall, Pennsylvania); Clement Romano (Strasburg, France) |
| ABSTRACT | A hybrid optical amplifier is proposed that includes a preamplifier element formed of single-clad Ho-doped optical fiber and a power amplifier element formed of single-clad Tm-doped (or Tm—Ho co-doped) optical fiber. The preamplifier is used to impart gain to an input signal propagating at a wavelength λS in the presence of a first pump beam operating at λP1, creating an amplified output over a defined transmission bandwidth. The power amplifier element is disposed at the output of the preamplifier element and provides an additional level of gain to the output of the preamplifier element in the presence of a second pump beam operating at λP2. A passband filter may be used between the preamplifier and the power amplifier to ensure that only wavelength components within the defined transmission bandwidth are applied as an output to the power amplifier. |
| FILED | Tuesday, May 19, 2020 |
| APPL NO | 16/878211 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/161 (20130101) H01S 3/0675 (20130101) H01S 3/0941 (20130101) H01S 3/1608 (20130101) H01S 3/1616 (20130101) H01S 3/1618 (20130101) H01S 3/06716 (20130101) H01S 3/06758 (20130101) Original (OR) Class H01S 3/08013 (20130101) H01S 3/10023 (20130101) H01S 3/10061 (20130101) H01S 3/094042 (20130101) H01S 3/094076 (20130101) H01S 2301/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11667799 | Bell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey) |
| ASSIGNEE(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey) |
| INVENTOR(S) | Howard Y. Bell (Princeton, New Jersey); Joshua E. Collins (Philadelphia, Pennsylvania); Robert A. Ferlis (McLean, Virginia); Kunik Lee (McLean, Virginia) |
| ABSTRACT | A cooperative vehicle-highway communication system allows vehicles and pedestrians to determine their location by sensing selected coatings on roadways, sidewalks, and other paved surfaces in both indoor and outdoor environments. The systems recognize intelligent materials under sensors to determine geo-location. The intelligent materials are incorporated into paints on the roadway surface to mark key locations. Additionally, vehicles recognize highway paint/markings and signs with intelligent paint that provide specialized message content to support driver information and control applications. The intelligent paint materials include a coating that absorbs light while converting the absorbed light to electromagnetic energy. This electromagnetic energy is read by sensors to recognize the materials. The sensors transform the electromagnetic energy into processing signals to determine operating characteristics of the vehicle, including position and motion characteristics, and to provide operation actions of the vehicle. For mobility impaired pedestrians, the precisely defined geo-locations |
| FILED | Wednesday, January 13, 2021 |
| APPL NO | 17/147818 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/22 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/0236 (20130101) G05D 2201/0213 (20130101) Image or Video Recognition or Understanding G06V 10/225 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11668236 | Wood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Trevor Howard Wood (Clifton Park, New York); Nikolai N. Pastouchenko (Glenville, New York); Kishore Ramakrishnan (Rexford, New York); Timothy Richard DePuy (Liberty Township, Ohio); Wendy Wenling Lin (Montgomery, Ohio); Robert William Davidoff (Pittsburgh, Pennsylvania) |
| ABSTRACT | An acoustic core includes an array of resonant cells. The array may include a plurality of coupled resonant cells respectively defining an antecedent resonant space and a subsequent resonant space, with at least one cell wall having one or more wall-apertures defining a pathway between the antecedent resonant space and the subsequent resonant space. The array may include a plurality of high-frequency resonant cells respectively defining a high-frequency resonant space and being matched with respective ones of the plurality of coupled resonant cells. A cross-sectional dimension of the one or more wall-apertures defining the pathway between the antecedent resonant space and the subsequent resonant space may be less than a cross-sectional dimension of the antecedent resonant space and/or a cross-sectional dimension of the subsequent resonant space. The array may include a plurality of partitioned resonant cells that have a partition integrally formed with at least one of a corresponding one or more cell walls and transecting the corresponding resonant space with at least one surface of the partition having an interface angle that is oblique or perpendicular relative to a plane parallel to a top face and/or a bottom face of the array of resonant cells. |
| FILED | Friday, July 24, 2020 |
| APPL NO | 16/938150 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/12 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/045 (20130101) Original (OR) Class Jet-propulsion Plants F02K 1/827 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/282 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11669653 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Xianghong Liu (Ann Arbor, Michigan); Yiheng Feng (Ann Arbor, Michigan) |
| ABSTRACT | A system and method for simulating a real roadway environment that can be used for testing of a real connected autonomous vehicle (CAV) on roadways using augmented reality to add simulated virtual environmental objects such as additional vehicles, pedestrians, and other obstructions to the nearby surroundings seen by the CAV under test. The method carried out by the system includes: receiving vehicle status information indicating the location of a connected real vehicle as it moves along a roadway; and generating a simulated environment of the real vehicle on the roadway using a mapped model of the roadway and the vehicle status information. The simulated environment includes one or more virtual objects such as vehicles, pedestrians, or other obstructions, and these simulated virtual objects may be sent to the real vehicle for testing of its response without requiring the use of real vehicles, pedestrians, or other obstructions. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 16/609996 |
| ART UNIT | 2467 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) Original (OR) Class Traffic Control Systems G08G 1/09 (20130101) Wireless Communication Networks H04W 4/44 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11666080 | Kozubal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| INVENTOR(S) | Mark A. Kozubal (Bozeman, Montana); Richard E. Macur (Manhattan, Montana); Yuval C. Avniel (Missoula, Montana); Maximilian Devane Hamilton (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Friday, August 05, 2022 |
| APPL NO | 17/882490 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670421 | Longmire et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Medable Inc. (Palo Alto, California) |
| ASSIGNEE(S) | Medable Inc. (Palo Alto, California) |
| INVENTOR(S) | Michelle Longmire (Palo Alto, California); Ingrid Oakley-Girvan (Henderson, California); Nick Moss (Los Alamos, New Mexico); Reem Yunis (Menlo Park, California); Anushka Manoj Gupta (Raleigh, North Carolina) |
| ABSTRACT | The instant system and method will be a scalable and flexible software platform to agnostically capture wearable, implantable, or external device data and create a digital biomarker for various disease conditions, care and analysis. The system and method also provides an informatics tool for automated data aggregation, integration, and machine learning algorithms to uniformly compare/contrast/couple data streams as a function of patient and context over time. The focus is on user engagement and usability, accessibility and reporting to the clinical care team, and usability by researchers interested in analyzing data and outcomes. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/219867 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/00 (20180101) G16H 40/67 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/50 (20180101) G16H 50/70 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11670903 | Delavaux et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cybel, LLC. (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Cybel, LLC. (Bethlehem, Pennsylvania) |
| INVENTOR(S) | Jean-Marc Delavaux (Pittstown, New Jersey); Robert E. Tench (Allentown, Pennsylvania); Alexandre Amavigan (Whitehall, Pennsylvania); Clement Romano (Strasburg, France) |
| ABSTRACT | A hybrid optical amplifier is proposed that includes a preamplifier element formed of single-clad Ho-doped optical fiber and a power amplifier element formed of single-clad Tm-doped (or Tm—Ho co-doped) optical fiber. The preamplifier is used to impart gain to an input signal propagating at a wavelength λS in the presence of a first pump beam operating at λP1, creating an amplified output over a defined transmission bandwidth. The power amplifier element is disposed at the output of the preamplifier element and provides an additional level of gain to the output of the preamplifier element in the presence of a second pump beam operating at λP2. A passband filter may be used between the preamplifier and the power amplifier to ensure that only wavelength components within the defined transmission bandwidth are applied as an output to the power amplifier. |
| FILED | Tuesday, May 19, 2020 |
| APPL NO | 16/878211 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/161 (20130101) H01S 3/0675 (20130101) H01S 3/0941 (20130101) H01S 3/1608 (20130101) H01S 3/1616 (20130101) H01S 3/1618 (20130101) H01S 3/06716 (20130101) H01S 3/06758 (20130101) Original (OR) Class H01S 3/08013 (20130101) H01S 3/10023 (20130101) H01S 3/10061 (20130101) H01S 3/094042 (20130101) H01S 3/094076 (20130101) H01S 2301/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11667970 | Bashir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Rashid Bashir (Champaign, Illinois); Anurup Ganguli (Champaign, Illinois); Farhad Kosari (Rochester, Minnesota) |
| ABSTRACT | Various methods and devices for spatial molecular analysis from tissue is provided. For example, a method of spatially mapping a tissue sample is provided with a microarray having a plurality of wells, wherein adjacent wells are separated by a shearing surface; overlaying said microarray with a tissue sample; applying a deformable substrate to an upper surface of said tissue sample; applying a force to the deformable substrate, thereby forcing underlying tissue sample into the plurality of wells; shearing the tissue sample along the shearing surface into a plurality of tissue sample islands, with each unique tissue sample island positioned in a unique well; and imaging or quantifying said plurality of tissue sample islands, thereby generating a spatial map of said tissue sample. The imaging and/or quantifying may use a nucleic acid amplification technique. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/939665 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/5085 (20130101) B01L 3/50851 (20130101) B01L 2200/0642 (20130101) B01L 2300/0819 (20130101) B01L 2300/0858 (20130101) B01L 2300/0893 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1003 (20130101) C12N 15/1003 (20130101) C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6827 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2521/107 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) G01N 2001/282 (20130101) G01N 2001/2873 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 25/10 (20190201) G16B 30/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP35202 | Fazio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Gennaro Fazio (Geneva, New York); Terence Lee Robinson (Geneva, New York); Herbert Sanders Aldwinckle (Geneva, New York); James N. Cummins (Alcoa, Tennessee) |
| ABSTRACT | A new and distinct variety of apple tree rootstock Malus domestica x Malus robusta hybrid ‘G.66’ is described herein. The new variety is a productive, yield efficient, semi-dwarfing rootstock that is resistant to fire blight (Erwinia amylovora) and crown rot (Phytophthora cactorum). The ‘G.66’ rootstock is useful in that it can be propagated clonally and used as a rootstock or root system for apple trees as well as for interstems of apple trees. |
| FILED | Monday, January 31, 2022 |
| APPL NO | 17/589341 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/7418 (20180501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11666223 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States Government as Represented by the Dept of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Cha-Min Tang (Wayne, Pennsylvania); Joseph Schmitt (Cupertino, California) |
| ABSTRACT | An apparatus provided for detecting tooth pulp vitality includes a handle, a pivot and a caliper. A pair of fiber optic lines pass through an interior of the handle, the pivot and the caliper. One of the fiber optic lines is a source line with a connector at an end of the source line and another of the fiber optic lines is a detector line with a connector at an end of the detector line. The source line is single mode in the handle and the detector line is multi mode. A system is also provided for detecting tooth pulp vitality that includes the apparatus. Additionally, a method is provided for detecting tooth pulp vitality that employs the apparatus. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 16/487775 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/0088 (20130101) Original (OR) Class A61B 5/0261 (20130101) A61B 5/682 (20130101) A61B 5/4547 (20130101) A61B 2090/3614 (20160201) Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 3/10 (20130101) A61C 19/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11667678 | Pahan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rush University Medical Center (Chicago, Illinois) |
| ASSIGNEE(S) | Rush University Medical Center (Chicago, Illinois) |
| INVENTOR(S) | Kalipada Pahan (Skokie, Illinois) |
| ABSTRACT | Compositions for inhibiting the binding between ACE2 and SARS-CoV-2 spike S1 are disclosed. Methods of treating COVID-19 are disclosed. Methods of making an in vivo model of COVID-19 are also disclosed. |
| FILED | Monday, March 21, 2022 |
| APPL NO | 17/699792 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/162 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/20022 (20130101) C12N 2770/20033 (20130101) C12N 2770/20071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11669426 | Gao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Xing Gao (Williamsburg, Virginia); Zhongshu Gu (Croton-on-Hudson, New York); Mehmet Kayaalp (White Plains, New York); Dimitrios Pendarakis (Westport, Connecticut) |
| ABSTRACT | A system and method for achieving power isolation across different cloud tenants and workloads is provided. The system includes a model of per-workload power consumption and an approach for attributing power consumption for each container. It allows a cloud provider to detect abnormally high power usage caused by specific containers and/or tenants, and to neutralize the emerging power attacks that exploit information leakages in the public container cloud. The approach also enables the provider to bill tenants for their specific power usage. Thus, the technique herein provides a mechanism that operates to attribute power consumption data for each container to defend against emerging power attacks, as well as to make it feasible to develop a cloud billing model based on power usage. The mechanism defends against emerging power attacks in container cloud offerings by implementing in a power-based namespace workflow in an OS kernel. The namespace workflow partitions the power consumption information for each container. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/638694 |
| ART UNIT | 2147 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Electric Digital Data Processing G06F 1/3203 (20130101) G06F 1/3206 (20130101) G06F 1/3234 (20130101) G06F 1/3296 (20130101) G06F 9/455 (20130101) G06F 9/45558 (20130101) G06F 11/3062 (20130101) Original (OR) Class G06F 11/3447 (20130101) G06F 21/53 (20130101) G06F 21/81 (20130101) G06F 21/755 (20170801) G06F 2009/45587 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 11670867 | Boyarsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Michael Boyarsky (Durham, North Carolina); Seyedmohammadreza Faghih Imani (Tempe, Arizona); David R. Smith (Durham, North Carolina) |
| ABSTRACT | According to various embodiments, systems and methods for suppressing grating lobes in a traveling-wave antenna system are disclosed. An apparatus can include a traveling-wave antenna array comprising a plurality of adjacent traveling-wave antennas. The apparatus also can include a phase diversity feed coupled to the traveling-wave antenna array. The phase diversity feed can be configured to provide phase diverse input to two or more of the plurality of adjacent traveling-wave antennas. |
| FILED | Monday, November 23, 2020 |
| APPL NO | 17/102310 |
| ART UNIT | 2896 — Digital Communications |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 13/20 (20130101) H01Q 21/0037 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Smithsonian Institution (SI)
| US 11668630 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Smithsonian Institution (Washington, District of Columbia) |
| ASSIGNEE(S) | Smithsonian Institution (Washington, District of Columbia) |
| INVENTOR(S) | Alexander Whitman Miller (Annapolis, Maryland); Amanda C. Reynolds (Annapolis, Maryland) |
| ABSTRACT | The current disclosure provides a gas-liquid falling film equilibration apparatus, systems incorporating the apparatus, and methods of their use. The apparatus comprises a chamber, an equilibration member within the chamber, liquid and gas inlet and outlets, such that a liquid introduced into the chamber from the liquid inlet contacts the upper portion of the outer surface of the equilibration member. The apparatus finds use in the measurement of dissolved gases in a variety of liquids including the measurement of carbon dioxide in water. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678556 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) Original (OR) Class G01N 33/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11667427 | Lee, Sr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | James Edward Lee, Sr. (St. Leonard, Maryland) |
| ABSTRACT | Embodiments of a reusable stackable shipping box are provided herein. The reusable stackable shipping box may be reused and cleaned without causing harm to the integrity of the box. In addition, the box is slightly tapered in shape such that the box may be stacked upon and within other boxes for ease in shipping and organization. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576703 |
| ART UNIT | 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 5/001 (20130101) Original (OR) Class B65D 5/10 (20130101) B65D 5/14 (20130101) B65D 5/0245 (20130101) B65D 5/0281 (20130101) B65D 5/4266 (20130101) B65D 5/4608 (20130101) B65D 5/48024 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/80 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11667552 | Jolly |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clifford D. Jolly (Parker, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clifford D. Jolly (Parker, Colorado) |
| ABSTRACT | A system and method for delivering silver ion biocide is described herein. The systems described relate to passing water from a water system through a silver ion release module and optional high-concentration silver ion release module. The system includes an analyzer, detector, and/or controller for monitoring the concentration of silver ion and adjusting the flow path, flow rate, temperature and/or pH of the water in order to obtain the desired concentration of silver ion. The system optionally includes other metal ions released into a water system, the concentration of which may be used to automatically calibrate the described system and/or cause the system to take actions based on the measured concentration of silver ion or of the second metal ion. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/080393 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/008 (20130101) C02F 1/505 (20130101) Original (OR) Class C02F 1/687 (20130101) C02F 1/688 (20130101) C02F 1/4606 (20130101) C02F 1/4672 (20130101) C02F 2201/4612 (20130101) C02F 2209/001 (20130101) C02F 2209/02 (20130101) C02F 2209/003 (20130101) C02F 2209/006 (20130101) C02F 2209/06 (20130101) C02F 2209/36 (20130101) C02F 2209/40 (20130101) C02F 2301/043 (20130101) C02F 2303/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 06, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230606.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page