FedInvent™ Patents

Patent Details for Tuesday, June 27, 2023 

This page was updated on Wednesday, June 28, 2023 at 02:38 AM GMT

Department of Health and Human Services (HHS) 

US 11684274 Mukkamala et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan);  University of Maryland (College Park, Maryland)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Ramakrishna Mukkamala (East Lansing, Michigan);  Anand Chandrasekhar (East Lansing, Michigan);  Jin-Oh Hahn (Rockville, Maryland)
ABSTRACT A system and method is presented for cuff-less blood pressure measurement in a mobile device. A key aspect of this disclosure is the discovery of a new location for blood pressure measurement at the fingertip of a subject and that reflectance-mode photoplethysmography can be used to help make this measurement. Through experiments in human subjects, it was discovered that it is indeed possible to measure systemic blood pressure by having a subject press the fingertip against a reflectance-mode photo-plethysmography-force sensor unit under visual guidance and then compute blood pressure from the resulting variable-amplitude blood volume oscillations and applied pressure via an oscillometric algorithm.
FILED Wednesday, June 02, 2021
APPL NO 17/336739
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0077 (20130101)
A61B 5/0261 (20130101)
A61B 5/0295 (20130101)
A61B 5/706 (20130101)
A61B 5/743 (20130101)
A61B 5/02055 (20130101)
A61B 5/02141 (20130101) Original (OR) Class
A61B 5/02225 (20130101)
A61B 5/02416 (20130101)
A61B 5/6898 (20130101)
A61B 2560/0462 (20130101)
A61B 2562/0238 (20130101)
A61B 2562/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684284 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
NIH Office of the Director (NIHOD)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Jin Hyung Lee (Stanford, California);  Ben A. Duffy (Palo Alto, California)
ABSTRACT The present disclosure provides a device for carrying out magnetic resonance imaging compatible optogenetics; and methods for using the device.
FILED Wednesday, July 20, 2016
APPL NO 15/743174
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class
A61B 5/0084 (20130101)
A61B 5/4041 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/05 (20130101)
A61N 1/086 (20170801)
A61N 5/067 (20210801)
A61N 5/0622 (20130101)
A61N 2005/063 (20130101)
A61N 2005/0651 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684306 Buxbaum et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES et al. (Bethesda, Maryland)
INVENTOR(S) Nataliya Buxbaum (Bethesda, Maryland);  Donald Farthing (Bethesda, Maryland);  Martin Lizak (Bethesda, Maryland);  Helmut Merkle (Bethesda, Maryland);  Natella Maglakelidze (Bethesda, Maryland);  Brittany Oliver (Bethesda, Maryland);  Ronald Gress (Bethesda, Maryland)
ABSTRACT This disclosure generally relates to stable water isotope labeling followed by detection via MRI (swiMRI), including deuterium MRI (dMRI) and 17O MRI, for visualizing rapidly dividing immune cells within target and/or lymphoid organ/s and/or tissues affected by chronic graft-versus-host disease (cGVHD). Using deuterated water labeling, followed by dMRI, a distinction in deuterium signal was detected in a target organ (e.g. liver) of the cGVHD-affected mice compared to unaffected mice, i.e. syngeneic HSCT recipient mice, where the host and donor are matched, and normal (unmanipulated) mice.
FILED Friday, October 27, 2017
APPL NO 16/345612
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0036 (20180801)
A61B 5/055 (20130101)
A61B 5/413 (20130101) Original (OR) Class
A61B 2503/40 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/3635 (20130101)
G01R 33/4828 (20130101)
G01R 33/34061 (20130101)
G01R 33/34069 (20130101)
G01R 33/34092 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684307 Anker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) CLEMSON UNIVERSITY RESEARCH FOUNDATION (Clemson, South Carolina)
ASSIGNEE(S) Clemson University Research Foundation (Clemson, South Carolina)
INVENTOR(S) Jeffrey Anker (Greenville, South Carolina);  Caleb Behrend (Pittsford, New York);  John Desjardins (Clemson, South Carolina)
ABSTRACT Implantable sensors for determining bone health that can be utilized in conjunction with orthopedic implants are described. The sensors can include passive strain gauges or passive chemical sensors that can be read by radiographic imaging techniques. Sensors can be affixed to implantable support devices so as to non-invasively monitor the effect of load on the implant; for instance, to provide a quantitative assessment of when a fracture is sufficiently healed to allow safe weight-bearing upon the limb. Alternatively, sensors can monitor the health of a local implant area; for instance, to monitor the implant area of early stage infection or healing of a fusion procedure.
FILED Thursday, April 23, 2020
APPL NO 16/856477
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0031 (20130101)
A61B 5/1071 (20130101)
A61B 5/4504 (20130101) Original (OR) Class
A61B 6/12 (20130101)
A61B 6/505 (20130101)
A61B 17/72 (20130101)
A61B 17/80 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/24 (20130101)
G01L 1/25 (20130101)
G01L 19/086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684315 Langer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Robert S. Langer (Newton, Massachusetts);  Carlo Giovanni Traverso (Newton, Massachusetts);  Yong Lin Kong (Salt Lake City, Utah)
ABSTRACT Gastric resident electronics, devices, systems, and related methods are generally provided. Some embodiments comprise administering (e.g., orally) an (electronic) resident structure to a subject (e.g., a patient) such that the (electronic) resident structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before exiting said location internal to the subject. In some embodiments, the resident structure is a gastric resident electronic. That is to say, in some embodiments, the resident structure is configured for relatively long gastric residence and comprises an electronic component. In some embodiments, the structures and components described herein may comprise one or more components configured for the delivery of an active substance(s) (e.g., a pharmaceutical agent) to the subject. In some embodiments, the device has a modular design, combining an electronic component(s) with materials configured for controlled and/or tunable degradation/dissolution to determine the time at which (gastric) residence is lost and the device exits the location internal to the subject. For example, in some embodiments, the resident structure comprises an electronic component and one or more additional components associated with the electronic component such that the resident structure is configured to be retained at a location internal to a subject for greater than or equal to 24 hours.
FILED Wednesday, November 28, 2018
APPL NO 16/202647
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0031 (20130101)
A61B 5/073 (20130101)
A61B 5/4238 (20130101)
A61B 5/6861 (20130101)
A61B 5/6871 (20130101)
A61B 5/6885 (20130101) Original (OR) Class
A61B 2560/0443 (20130101)
A61B 2562/162 (20130101)
A61B 2562/0285 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 31/002 (20130101)
A61M 2205/0216 (20130101)
A61M 2205/0272 (20130101)
A61M 2205/3523 (20130101)
A61M 2210/1053 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684328 Dejongh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) ProtonVDA LLC (Naperville, Illinois)
ASSIGNEE(S) ProtonVDA LLC (Naperville, Illinois)
INVENTOR(S) Don F. Dejongh (Naperville, Illinois);  Victor Rykalin (Batavia, Illinois)
ABSTRACT A medical imaging system includes a first tracking detector and a second tracking detector. The tracking detectors are spaced to allow for an object to be present between the first tracking detector and the second tracking detector. The system also includes a residual range detector adjacent the first tracking detector. The residual range detector includes: (1) a scintillator material having a first surface at least partially covered with an anti-reflection material and a second surface facing the first tracking detector and (2) at least one photon detector coupled to the scintillator material at a third surface of the scintillator material different than the first surface and opposite the second surface.
FILED Monday, April 19, 2021
APPL NO 17/234540
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/582 (20130101)
A61B 6/4216 (20130101)
A61B 6/4258 (20130101) Original (OR) Class
A61B 6/5205 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2005/1054 (20130101)
A61N 2005/1087 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/29 (20130101)
G01T 1/1603 (20130101)
G01T 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684345 Alizad et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Azra Alizad (Rochester, Minnesota);  Mahdi Bayat (Cleveland, Ohio);  Mostafa Fatemi (Rochester, Missouri)
ABSTRACT Methods and systems for producing a visually-perceived representation of a sub-millimeter-sized blood vessel located at a depth of many centimeters in the biological tissue, in which the background clutter is suppressed (by at least 30 dB using SVT and additional 23 dB using a combination of morphology filtering and vessel enhancement filtering) as compared to an image obtained with the use of a B-mode ultrasound imaging, while at the same time maintaining the morphology of the blood vessel.
FILED Monday, November 29, 2021
APPL NO 17/536625
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/06 (20130101)
A61B 8/14 (20130101)
A61B 8/463 (20130101)
A61B 8/488 (20130101)
A61B 8/0891 (20130101)
A61B 8/4444 (20130101)
A61B 8/5223 (20130101) Original (OR) Class
A61B 8/5246 (20130101)
A61B 8/5276 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684404 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Chen Yang (Newton, Massachusetts);  Ji-Xin Cheng (Newton, Massachusetts);  Nan Zheng (Allston, Massachusetts);  Yueming Li (Brighton, Massachusetts);  Ying Jiang (Brighton, Massachusetts);  Lu Lan (Allston, Massachusetts);  Linli Shi (Allston, Massachusetts)
ABSTRACT A tapered fiber optoacoustic emitter includes a nanosecond laser configured to emit laser pulses and an optic fiber. The optic fiber includes a tip configured to guide the laser pulses. The tip has a coating including a diffusion layer and a thermal expansion layer, wherein the diffusion layer includes epoxy and zinc oxide nanoparticles configured to diffuse the light while restricting localized heating. The thermal expansion layer includes carbon nanotubes (CNTs) and Polydimethylsiloxane (PDMS) configured to convert the laser pulses to generate ultrasound. The frequency of the ultrasound is tuned with a thickness of the diffusion layer and a CNT concentration of the expansion layer.
FILED Wednesday, March 09, 2022
APPL NO 17/690948
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0035 (20130101)
A61B 5/0059 (20130101)
A61B 5/0095 (20130101)
A61B 8/4416 (20130101)
A61B 8/4483 (20130101)
A61B 18/04 (20130101) Original (OR) Class
A61B 18/26 (20130101)
A61B 2018/266 (20130101)
A61B 2018/2205 (20130101)
A61B 2018/2244 (20130101)
A61B 2018/2261 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/10 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/2431 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 15/8968 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/004 (20130101)
G02B 6/021 (20130101)
G02B 6/34 (20130101)
G02B 6/02033 (20130101)
G02B 6/02104 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684583 Traverso et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Carlo Giovanni Traverso (Newton, Massachusetts);  Ashok Kakkar (Pointe-Claire, Canada);  Joshua Korzenik (Waban, Massachusetts);  Robert S. Langer (Newton, Massachusetts);  Sufeng Zhang (Cambridge, Massachusetts)
ABSTRACT Compositions, articles, and methods for targeted drug delivery, such as thermoresponsive hydrogel polymers, are generally provided. In one aspect, the compositions and articles comprise a thermoresponsive hydrogel polymer comprising a releasable therapeutic agent. In some cases, the compositions described herein have advantageous combinations of properties including mechanical strength, biocompatibility, tunable charge densities, thermal responsiveness, drug loading, and/or configurations for targeted drug delivery. In one embodiment, the composition comprises a solution comprising a thermoresponsive polymer including one or more ligands attached to the polymer, wherein the solution is configured to undergo a sol-to-gel transition under physiological conditions. In another embodiment, the composition comprises a plurality of nanoparticles e.g., associated with the thermoresponsive polymer. In yet another embodiment, the composition comprises a therapeutic agent e.g., associated with the nanoparticles and/or thermoresponsive polymer.
FILED Friday, December 08, 2017
APPL NO 16/080737
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0024 (20130101)
A61K 9/5026 (20130101)
A61K 9/5036 (20130101)
A61K 9/5052 (20130101) Original (OR) Class
A61K 9/5169 (20130101)
A61K 31/58 (20130101)
A61K 38/193 (20130101)
A61K 47/34 (20130101)
A61K 47/54 (20170801)
A61K 47/58 (20170801)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/54 (20130101)
C08F 220/56 (20130101)
C08F 224/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684599 Bazan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana);  University of Southern California (Los Angeles, California)
ASSIGNEE(S) Board of Supervisors of Lousiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana);  University of Southern California (Los Angeles, California)
INVENTOR(S) Nicolas G. Bazan (New Orleans, Louisiana);  Nicos A. Petasis (Los Angeles, California)
ABSTRACT Provided are compounds, pharmaceutical compositions, cosmetic and dermatological compositions or nutritional supplement compositions, comprising omega-3 very-long-chain polyunsaturated fatty acids (n-3 VLC-PUFAs) and/or their endogenous hydroxylated derivatives thereof, known as elovanoids. This disclosure provides methods for neuroprotection, organ and tissue protection or restoration, prevention or slowing down of aging-related diseases and conditions, and sustainment of function during the aging process.
FILED Thursday, September 19, 2019
APPL NO 16/576456
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 33/12 (20160801)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/0029 (20130101)
A61K 31/202 (20130101) Original (OR) Class
A61K 31/685 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
A61P 39/06 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684601 Ye et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Jiangbin Ye (Stanford, California);  Yang Li (Stanford, California)
ABSTRACT Methods are provided for the treatment of cancer by administering a combination of metabolic interventions to differentiate the cancer cells. The effect on the targeted cancer cell is enhanced relative to a regimen in which a single agent is used; and the effect may be synergistic relative to a regimen in which a single agent is used.
FILED Friday, February 14, 2020
APPL NO 16/792012
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 31/22 (20130101) Original (OR) Class
A61K 31/203 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684603 Martinez-Lemus et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Curators Of The University Of Missouri (Columbia, Missouri)
ASSIGNEE(S) CURATORS OF THE UNIVERSITY OF MISSOURI UNIVERSITY (Columbia, Missouri)
INVENTOR(S) Luis A. Martinez-Lemus (Columbia, Missouri);  Christopher A. Foote (Columbia, Missouri);  Jaume Padilla (Columbia, Missouri)
ABSTRACT Disclosed are methods for ameliorating glycocalyx damage by administering a neuraminidase inhibitor. Also disclosed are methods for treating endothelial dysfunction and for improving flow mediated dilation.
FILED Wednesday, October 10, 2018
APPL NO 16/754814
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/196 (20130101)
A61K 31/215 (20130101)
A61K 31/351 (20130101) Original (OR) Class
A61K 31/445 (20130101)
A61K 38/47 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684609 Baraban
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents Of The University Of California (Oakland, California)
ASSIGNEE(S) The Regents Of The University Of California (Oakland, California)
INVENTOR(S) Scott C. Baraban (Novato, California)
ABSTRACT Provided, inter alia, are methods for treating an epilepsy disorder using clemizole, a clemizole analog, or pharmaceutical salts thereof.
FILED Thursday, February 08, 2018
APPL NO 15/892204
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/19 (20130101)
A61K 31/20 (20130101)
A61K 31/20 (20130101)
A61K 31/27 (20130101)
A61K 31/27 (20130101)
A61K 31/36 (20130101)
A61K 31/55 (20130101)
A61K 31/137 (20130101)
A61K 31/137 (20130101)
A61K 31/195 (20130101)
A61K 31/195 (20130101)
A61K 31/197 (20130101)
A61K 31/197 (20130101)
A61K 31/357 (20130101)
A61K 31/433 (20130101)
A61K 31/433 (20130101)
A61K 31/473 (20130101)
A61K 31/473 (20130101)
A61K 31/551 (20130101)
A61K 31/551 (20130101)
A61K 31/4015 (20130101)
A61K 31/4166 (20130101)
A61K 31/4184 (20130101) Original (OR) Class
A61K 31/4184 (20130101)
A61K 31/5513 (20130101)
A61K 31/7048 (20130101)
A61K 31/7048 (20130101)
A61K 33/00 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684614 Abergel et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Rebecca J. Abergel (Kensington, California);  Taylor A. Choi (South San Francisco, California);  Kenneth N. Raymond (Berkeley, California);  David K. Shuh (Oakland, California)
ABSTRACT Provided herein are pharmaceutical formularions comprising a 1,2-HOPO chelating agent and/or 3,2-HOPO chelating agent.
FILED Tuesday, September 05, 2017
APPL NO 16/330601
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0056 (20130101)
A61K 9/0095 (20130101)
A61K 9/1611 (20130101)
A61K 9/1623 (20130101)
A61K 9/1652 (20130101)
A61K 9/2009 (20130101)
A61K 9/2018 (20130101)
A61K 9/2054 (20130101)
A61K 31/444 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 39/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684626 Slaga et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Board of Regents, the University of Texas System (, None)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Thomas J. Slaga (San Antonio, Texas);  Jacob Junco (San Antonio, Texas);  Huiyun Liang (San Antonio, Texas);  Sara Reyna (San Antonio, Texas)
ABSTRACT Certain embodiments are directed to methods and compositions for treating obesity, diabetes, and/or cancer with a combination of ursolic acid and resveratrol.
FILED Saturday, April 17, 2021
APPL NO 17/233455
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 31/05 (20130101)
A61K 31/05 (20130101)
A61K 31/19 (20130101)
A61K 31/19 (20130101)
A61K 31/56 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/04 (20180101)
A61P 3/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684638 Prabha et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Swayam Prabha (Minneapolis, Minnesota);  Tanmoy Sadhukha (Minneapolis, Minnesota);  Buddhadev Layek (Minneapolis, Minnesota)
ABSTRACT A method for targeted delivery of cargo to a target locus in a subject and components of the system. Generally, the method includes administering to the subject a cell that has an artificial saccharide-derived target presented on the surface of the cell, allowing the cell to localize to a target locus in the subject, then administering to the subject an agent that specifically binds to the artificial target. In some embodiments, the agent can include a therapeutic compound. In some embodiments, the agent can include a detectable label. In some of these embodiments, that method can further include detecting the detectable label.
FILED Thursday, February 16, 2017
APPL NO 15/434640
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/28 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0006 (20130101)
C12N 5/0663 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684653 Chang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Cleveland Clinic Foundation (Cleveland, Ohio)
ASSIGNEE(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
INVENTOR(S) Eugene Chang (Chicago, Illinois);  Jeannette Messer (Chicago, Illinois)
ABSTRACT The present disclosure relates to compositions and methods for reducing virulence of microorganisms. In particular, the present invention provides HMGB1 and variants and mimetics thereof for use in reducing virulence of microorganisms (e.g., in disease).
FILED Tuesday, March 03, 2020
APPL NO 16/807792
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1709 (20130101) Original (OR) Class
A61K 47/64 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/00 (20180101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684662 Sampson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) John H Sampson (Durham, North Carolina);  Duane A Mitchell (Durham, North Carolina);  Kristen A Batich (Durham, North Carolina);  Michael D Gunn (Durham, North Carolina)
ABSTRACT Pre-conditioning a vaccine site with a potent recall antigen such as tetanus/diphtheria (Td) toxoid can significantly improve the lymph node homing and efficacy of tumor antigen-specific DC vaccines. Patients given Td had enhanced DC migration bilaterally and significantly improved survival. In mice, Td pre-conditioning also enhanced bilateral DC migration and suppressed tumor growth in a manner dependent on the chemokines CCL3 and CCL21 and Td-activated CD4+ T cells. Interference with any component of this axis markedly reduced Td-mediated DC migration and antitumor responses. Our clinical studies and corroborating investigations in mice suggest that pre-conditioning with a potent recall antigen represents a viable strategy to increase DC homing to lymph nodes and improve antitumor immunotherapy.
FILED Sunday, July 11, 2021
APPL NO 17/372475
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/195 (20130101)
A61K 39/05 (20130101)
A61K 39/08 (20130101) Original (OR) Class
A61K 39/0011 (20130101)
A61K 39/12 (20130101)
A61K 39/39 (20130101)
A61K 39/092 (20130101)
A61K 39/102 (20130101)
A61K 49/06 (20130101)
A61K 49/0008 (20130101)
A61K 2039/53 (20130101)
A61K 2039/54 (20130101)
A61K 2039/58 (20130101)
A61K 2039/70 (20130101)
A61K 2039/545 (20130101)
A61K 2039/585 (20130101)
A61K 2039/5154 (20130101)
A61K 2039/5158 (20130101)
A61K 2039/55544 (20130101)

Peptides
C07K 14/33 (20130101)
C07K 14/34 (20130101)
C07K 14/285 (20130101)
C07K 14/523 (20130101)
C07K 14/3156 (20130101)
C07K 14/4748 (20130101)
C07K 2319/55 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/16134 (20130101)
C12N 2710/16171 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684666 Ruprecht et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The University of Louisiana at Lafayette (Lafayette, Louisiana)
ASSIGNEE(S) University of Louisiana at Lafayette (Lafayette, Louisiana)
INVENTOR(S) Ruth M. Ruprecht (San Antonio, Texas);  Samir K. Lakhashe (San Antonio, Texas)
ABSTRACT Provided here are certain recombinant HIV compositions and animal models to evaluate prophylactic and therapeutic antiviral compositions.
FILED Tuesday, November 07, 2017
APPL NO 16/348104
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/027 (20130101)
A01K 2207/10 (20130101)
A01K 2207/20 (20130101)
A01K 2227/106 (20130101)
A01K 2267/0337 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 39/21 (20130101) Original (OR) Class

Peptides
C07K 2319/40 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2740/15022 (20130101)
C12N 2740/16021 (20130101)
C12N 2740/16122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684667 Baker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
APPLICANT(S) LOYOLA UNIVERSITY CHICAGO (Maywood, Illinois)
ASSIGNEE(S) LOYOLA UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S) Susan Baker (Elmhurst, Illinois);  Xufang Deng (Lyons, Illinois)
ABSTRACT Coronaviruses, vaccines comprising the same, and methods for preventing disease. One embodiment of such includes a live, attenuated coronavirus comprising a variant replicase gene encoding polyproteins comprising a non-structural protein (nsp)-15, the replicase gene encoding the nsp15 and causes any change, including mutations and/or deletions, that affects the stability or activity of the nsp15.
FILED Friday, March 02, 2018
APPL NO 15/910617
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/215 (20130101) Original (OR) Class
A61K 2039/5254 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)
C12N 2770/20022 (20130101)
C12N 2770/20034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684670 Herold et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Albert Einstein College of Medicine (Bronx, New York)
ASSIGNEE(S) ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York)
INVENTOR(S) Betsy C. Herold (Rowayton, Connecticut);  Clare Burn Aschner (Bronx, New York)
ABSTRACT Methods of vaccinating, immunizing and/or treating a subject against a herpes simplex virus infection or a disease caused by a herpes simplex virus infection comprise administering to the subject an effective amount of a HSV-2 single-cycle virus and an effective amount of a recombinant HSV-2 glycoprotein D, wherein the HSV-2 single-cycle virus comprises HSV-2 having a deletion of glycoprotein D-encoding gene in the genome and the HSV-2 is phenotypically complemented with an HSV-1 glycoprotein D on a lipid bilayer of the HSV-2.
FILED Tuesday, June 01, 2021
APPL NO 17/335548
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 39/245 (20130101) Original (OR) Class
A61K 2039/54 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/22 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/16621 (20130101)
C12N 2710/16622 (20130101)
C12N 2710/16634 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684673 Bakaletz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio)
ASSIGNEE(S) Research Institute at Nationwide Children's Hospital (Columbus, Ohio)
INVENTOR(S) Lauren O. Bakaletz (Hilliard, Ohio);  Steven D. Goodman (Hilliard, Ohio)
ABSTRACT This disclosure provides isolated or recombinant polypeptides that are useful to vaccinate individuals suffering from chronic/recurrent biofilm disease or as a therapeutic for those with an existing infection. The individual's immune system will then naturally generate antibodies which prevent or clear these bacteria from the host by interfering with the construction and or maintenance of a functional protective biofilm. Alternatively, antibodies to the polypeptides can be administered to treat or prevent infection. Bacteria that are released from the biofilm by our technology are more readily cleared by the remainder of the host's immune system.
FILED Friday, January 15, 2021
APPL NO 17/150731
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 8/64 (20130101)
A61K 39/12 (20130101)
A61K 39/40 (20130101) Original (OR) Class
A61K 39/395 (20130101)
A61K 2039/507 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/54 (20130101)
A61L 29/16 (20130101)
A61L 2300/404 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Specific Use of Cosmetics or Similar Toilet Preparations
A61Q 11/00 (20130101)
A61Q 17/005 (20130101)

Peptides
C07K 16/12 (20130101)
C07K 16/18 (20130101)
C07K 16/1217 (20130101)
C07K 16/1232 (20130101)
C07K 16/1242 (20130101)
C07K 16/1271 (20130101)
C07K 16/1275 (20130101)
C07K 2317/34 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/62 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684675 Kessler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Julian Kessler (Salt Lake City, Utah);  Michael S. Yu (Salt Lake City, Utah);  Yang Li (Salt Lake City, Utah)
ABSTRACT Disclosed are peptide conjugates comprising an active agent, a spacer moiety, and a dimeric collagen hybridizing peptide comprising a first and second collagen hybridizing peptide, a linker; and a branch point, wherein the first and second collagen hybridizing peptides comprise the sequence of at least (GXY)n, wherein G is glycine, wherein X and Y are any amino acid, and wherein n is any number between 3 and 12. Also disclosed are methods of detecting denatured collagen in a sample comprising contacting a composition comprising any one of the disclosed peptide conjugates to a sample, wherein the active agent comprises a therapeutic agent, and detecting the presence or absence of binding of the peptide conjugate to denatured collagen, the presence of binding indicating the presence of denatured collagen in the sample. Also disclosed are methods of treating a disease or injury involving collagen damage comprising administering to a subject having a disease or injury involving collagen damage any one of the disclosed peptide conjugates.
FILED Wednesday, February 24, 2021
APPL NO 17/184289
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/64 (20170801)
A61K 47/65 (20170801)
A61K 47/641 (20170801) Original (OR) Class

Peptides
C07K 14/78 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6887 (20130101)
G01N 2333/78 (20130101)
G01N 2500/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684676 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Yong Zhang (Los Angeles, California);  Zhefu Dai (Los Angeles, California);  Xiao-Nan Zhang (Los Angeles, California)
ABSTRACT Antibody-drug conjugates, compositions thereof, and methods use. The antibody-drug conjugates include a fusion protein comprising an antibody covalently linked to an ADP-ribosyl cyclase protein via a peptide linker moiety at one or more of a C-terminus or N-terminus of a heavy or light chain of the antibody, a NAD or NMN analogue, and a payload such that the NAD or NMN analogue is conjugated to both the payload and the ADP-ribosyl cyclase protein.
FILED Monday, May 10, 2021
APPL NO 17/996313
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/6807 (20170801)
A61K 47/6815 (20170801) Original (OR) Class
A61K 47/6851 (20170801)
A61K 47/6889 (20170801)
A61K 2039/505 (20130101)

Peptides
C07K 16/2851 (20130101)
C07K 2317/90 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2497 (20130101)

Enzymes
C12Y 302/02006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684679 Engelhardt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) University of Iowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) John F. Engelhardt (Iowa City, Iowa);  Ziying Yan (Iowa City, Iowa)
ABSTRACT An isolated recombinant parvovirus vector comprising a synthetic enhancer comprising plurality of enhancer sequences operably linked to a promoter, and methods of using the vector, are provided.
FILED Tuesday, March 07, 2017
APPL NO 16/082767
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/55 (20170801)
A61K 48/0066 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2750/14041 (20130101)
C12N 2750/14043 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684681 Pease et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Leonard F. Pease (Salt Lake City, Utah);  Hedieh Saffari (Salt Lake City, Utah);  Gerald J. Gleich (Salt Lake City, Utah);  Kristin M. Leiferman (Salt Lake City, Utah);  Kathryn A. Peterson (Salt Lake City, Utah);  Russell Morris Condie (Salt Lake City, Utah)
ABSTRACT Disclosed are methods of detecting eosinophil degranulation in the respiratory tract of subjects. Also, disclosed are methods of producing medical images of the respiratory tract of subjects. The method can include administering radiolabeled heparin to the respiratory tract of subjects, wherein the radiolabeled heparin binds to one or more eosinophil granule protein in the mucosal tissue of the respiratory tract.
FILED Monday, July 19, 2021
APPL NO 17/379402
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/08 (20130101)
A61K 51/0491 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684763 Falo, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Louis D. Falo, Jr. (Wexford, Pennsylvania);  Geza Erdos (Wexford, Pennsylvania)
ABSTRACT A method of forming a microneedle array can include forming a microneedle array that has one or more bioactive component. The microneedle array can include a base portion and plurality of microneedles extending from the base portion, and the one or more bioactive components can be combined with other components to exhibit specific release kinetics when the microneedle array is inserted into the skin of a patient.
FILED Monday, October 17, 2016
APPL NO 15/768514
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0021 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0015 (20130101) Original (OR) Class
A61M 2037/0046 (20130101)
A61M 2037/0053 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684922 Weiss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Paul S. Weiss (Los Angeles, California);  Steven J. Jonas (Hawthorne, California);  Dan Wilkinson (New York, New York);  Adam Z. Stieg (Pasadena, California);  Jason Belling (Los Angeles, California)
ABSTRACT A microfluidic-based device and system is disclosed for the high-throughput intracellular delivery of biomolecular cargo to cells (eukaryotic or prokaryotic) or enveloped viruses. Cargo integration occurs due to transient membrane permeabilization by exposure to bulk acoustic waves (BAWs) transduced from surface acoustic waves (SAWs) generated by a rapidly oscillating piezoelectric substrate. In this approach, temporary pores are established across the cellular membrane as cells are partially deformed and squeezed or subject to shearing forces as they travel through the vibrational modes created within the microfludic channel(s) of the device.
FILED Tuesday, February 13, 2018
APPL NO 16/485424
ART UNIT 1796 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101) Original (OR) Class
B01L 2400/0436 (20130101)
B01L 2400/0442 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/87 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 41/04 (20130101)
H01L 41/081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685711 De La Cruz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Georgia State University Research Foundation, Inc. (Atlanta, Georgia)
ASSIGNEE(S) GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia)
INVENTOR(S) Ladie Kimberly c. De La Cruz (Atlanta, Georgia);  Xingyue Ji (Atlanta, Georgia);  Zhixiang Pan (Atlanta, Georgia);  Binghe Wang (Atlanta, Georgia)
ABSTRACT The present invention generally relates to carbon monoxide releasing compounds and compositions, and their use as carbon monoxide prodrugs.
FILED Thursday, August 09, 2018
APPL NO 16/637737
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 49/757 (20130101)
C07C 62/38 (20130101)
C07C 323/22 (20130101)
C07C 323/65 (20130101) Original (OR) Class
C07C 2602/42 (20170501)

Heterocyclic Compounds
C07D 335/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685717 Arnaout
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) M. Amin Arnaout (Chestnut Hill, Massachusetts)
ABSTRACT The present application relates to polypeptides which are integrin antagonists. Methods of preparing the integrin antagonists and methods of treating diseases and disorders associated with abnormal levels and/or expression of one or more integrins are also provided.
FILED Thursday, August 08, 2019
APPL NO 17/266339
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/04 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/13 (20130101)

Heterocyclic Compounds
C07D 211/22 (20130101) Original (OR) Class

Peptides
C07K 14/4703 (20130101)
C07K 14/70546 (20130101)
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US 11685723 Ebright et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Rutgers, the State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S) Richard H. Ebright (New Brunswick, New Jersey);  Yon W. Ebright (New Brunswick, New Jersey)
ABSTRACT The invention provides compounds of formula Ia, Ib, Ic, or as well as compositions comprising a compound of formula Ia-Id, methods of making such compounds, and methods of using such compounds, e.g., as inhibitors of bacterial RNA polymerase and as antibacterial agents.
FILED Tuesday, February 12, 2019
APPL NO 16/969530
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 47/12 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
A61P 31/06 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/05 (20130101)
C07B 2200/07 (20130101)

Heterocyclic Compounds
C07D 309/38 (20130101) Original (OR) Class
C07D 417/06 (20130101)
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US 11685763 Cleland et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Rensselaer Polytechnic Institute (Troy, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Timothy Paul Cleland (Pflugerville, Texas);  Deepak Vashishth (Glenmont, New York)
ABSTRACT Embodiments of the invention relate generally to protein extraction and, more generally, to bone protein extraction methods that do not require demineralization. In one embodiment, the invention provides a method comprising: mixing a bone sample and a quantity of an extraction buffer comprising: ammonium phosphate dibasic; or ammonium phosphate dibasic and ammonium bicarbonate; or ammonium phosphate dibasic, ammonium bicarbonate, and guanidine HCl; or sodium phosphate dibasic and sodium bicarbonate; or sodium phosphate dibasic, sodium bicarbonate, and guanidine HCl; or potassium phosphate dibasic and potassium bicarbonate; or potassium phosphate dibasic, potassium bicarbonate, and guanidine HCl; and incubating the bone sample/extraction buffer mixture.
FILED Friday, March 01, 2019
APPL NO 16/289782
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/32 (20130101)

Peptides
C07K 1/145 (20130101) Original (OR) Class
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US 11685767 McFadden et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Douglas Grant McFadden (Tempe, Arizona);  Alfred S. Lewin (Gainesville, Florida);  Alexandra Rose Lucas (Tempe, Arizona);  Cristhian J. Ildefonso (Gainesville, Florida);  Mohammed Masmudur Rahman (Chandler, Arizona)
ABSTRACT Disclosed are methods and compositions for preventing, treating, and/or ameliorating one or more symptoms of inflammation in a mammal. In particular, viral vectors and medicaments containing them are disclosed, which are useful in the prophylaxis, therapy, or amelioration of symptoms of one or more inflammatory-mediated mammalian diseases, such as age-related macular degeneration (AMD), arthritis, Bechet's disease, Best macular dystrophy, corneal inflammation, diabetic retinopathy, drusen formation, dry AMD, dry eye, geographic atrophy, glaucomaocular neovascularization, Lupus erythematosus, macular degeneration, Mallatia Leventinese and Doyne honeycomb retinal dystrophy, nephritis, ocular hypertension, ocular inflammation, recurrent uveitis, Sorsby fundus dystrophy, vasculitis, vitreoretinopathy, wet AMD, or related disorders. In exemplary methods, administration of a pharmaceutical composition comprising a recombinant viral vector that delivers a secretable and cell-penetrating M013 protein or peptide to a subject in need thereof facilitated treatment of particular human disorders such as AMD, ocular neovascularization, uveitis, and related inflammatory ocular disease.
FILED Friday, September 09, 2016
APPL NO 15/261599
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 38/162 (20130101)
A61K 48/00 (20130101)
A61K 48/005 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2710/24022 (20130101)
C12N 2750/14143 (20130101)
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US 11685774 Hotamisligil et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President And Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Gokhan S. Hotamisligil (Wellesley, Massachusetts);  Haiming Cao (Bethesda, Maryland)
ABSTRACT A method of reducing a symptom of a clinical disorder characterized by aberrantly elevated circulating aP2 is carried out by administering to a subject an inhibitor of secreted aP2, secretion of aP2, or a serum aP2 blocking agent. For example, glucose intolerance is reduced following administration of such an inhibitor or agent. Exemplary compositions inhibit cellular secretion of aP2 or bind to circulating aP2, thereby reducing the level or activity of aP2 in blood or serum.
FILED Monday, November 23, 2020
APPL NO 17/102329
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 2317/34 (20130101)
C07K 2317/76 (20130101)
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US 11685775 Mirza et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) XOMA Technology Ltd. (Emeryville, California);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) XOMA TECHNOLOGY LTD. (Emeryville, California);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Amer M. Mirza (San Francisco, California);  Rosemary J. Akhurst (Tiburon, California);  Ou Li (Dublin, California)
ABSTRACT The present disclosure relates, in general, to combination therapy using an inhibitor of transforming growth factor beta (TGFβ) and an inhibitor of programmed cell death protein 1 (PD-1) for treating cancer or preventing recurrence of cancer diseases such as lung cancer, prostate cancer, breast cancer, hepatocellular cancer, esophageal cancer, colorectal cancer, pancreatic cancer, bladder cancer, kidney cancer, ovarian cancer, stomach cancer, fibrotic cancer, glioma and melanoma, and metastases thereof.
FILED Monday, June 15, 2020
APPL NO 16/901596
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/57 (20130101)
A61K 2039/507 (20130101)

Peptides
C07K 16/22 (20130101) Original (OR) Class
C07K 16/2803 (20130101)
C07K 16/2818 (20130101)
C07K 2317/51 (20130101)
C07K 2317/56 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/515 (20130101)
C07K 2317/565 (20130101)
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US 11685782 Shi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Yang Shi (Newton, Massachusetts);  Wanqiang Sheng (Allston, Massachusetts);  Arlene H. Sharpe (Brookline, Massachusetts);  Martin W. LaFleur (Boston, Massachusetts)
ABSTRACT Provided herein are methods of treating cancer using LSD1 inhibitors in combination with immunotherapy.
FILED Tuesday, October 23, 2018
APPL NO 16/758474
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2818 (20130101) Original (OR) Class
C07K 16/2827 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1137 (20130101)
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US 11685898 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Rhode Island Hospital (Providence, Rhode Island)
ASSIGNEE(S) RHODE ISLAND HOSPITAL (Providence, Rhode Island)
INVENTOR(S) Qian Chen (Barrington, Rhode Island);  Chathuraka T. Jayasuriya (Barrington, Rhode Island)
ABSTRACT This invention is directed to, inter alia, stable cartilage-derived progenitor cell lines as well as methods for producing stable cartilage-derived progenitor cell lines from diseased human cartilaginous tissues and lesions. Also provided herein are methods for using cartilage-derived progenitor cell lines for treatment of cartilage and bone degenerative diseases.
FILED Tuesday, February 28, 2017
APPL NO 16/081029
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/32 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0655 (20130101) Original (OR) Class
C12N 15/86 (20130101)
C12N 2740/10043 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5044 (20130101)
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US 11685901 Evans et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Salk Institute for Biological Studies (La Jolla, California)
ASSIGNEE(S) Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S) Ronald Evans (La Jolla, California);  Michael Downes (La Jolla, California);  Annette Atkins (La Jolla, California);  Eiji Yoshihara (La Jolla, California);  Ruth Yu (La Jolla, California)
ABSTRACT The invention features pancreatic islet and pancreatic organoids, and cell cultures and methods that are useful for the rapid and reliable generation of pancreatic islet and pancreatic islet organoids. The invention also features methods of treating pancreatic diseases and methods of identifying agents that are useful for treatment of pancreatic diseases, such as type 2 diabetes and pancreatic cancer, using the pancreatic islet and pancreatic organoids of the invention.
FILED Monday, March 28, 2022
APPL NO 17/706272
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/39 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0677 (20130101) Original (OR) Class
C12N 2501/16 (20130101)
C12N 2501/117 (20130101)
C12N 2501/385 (20130101)
C12N 2501/395 (20130101)
C12N 2501/415 (20130101)
C12N 2501/727 (20130101)
C12N 2501/999 (20130101)
C12N 2502/28 (20130101)
C12N 2502/1382 (20130101)
C12N 2503/02 (20130101)
C12N 2506/02 (20130101)
C12N 2506/45 (20130101)
C12N 2513/00 (20130101)
C12N 2533/52 (20130101)
C12N 2533/54 (20130101)
C12N 2533/90 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5088 (20130101)
G01N 2800/04 (20130101)
G01N 2800/7028 (20130101)
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US 11685916 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Feng Zhang (Cambridge, Massachusetts);  Jonathan Gootenberg (Cambridge, Massachusetts);  David Benjamin Turitz Cox (Cambridge, Massachusetts);  Omar Abudayyeh (Cambridge, Massachusetts);  Soumya Kannan (Cambridge, Massachusetts)
ABSTRACT The disclosure provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a RNA-targeting Cas13 protein, at least one guide molecule, and at least one adenosine deaminase protein or catalytic domain thereof.
FILED Wednesday, May 13, 2020
APPL NO 15/930478
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 2319/71 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/102 (20130101) Original (OR) Class

Enzymes
C12Y 305/04004 (20130101)
C12Y 305/04005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685917 Bauer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts);  CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Daniel E. Bauer (Cambridge, Massachusetts);  Stuart H. Orkin (Brookline, Massachusetts);  Neville Espi Sanjana (New York, New York);  Ophir Shalem (Albany, California);  Jason Wright (Cambridge, Massachusetts);  Feng Zhang (Cambridge, Massachusetts)
ABSTRACT The application relates to a deep scanning mutagenesis library to interrogate phenotypic changes in a population of cells comprising a plurality of CRISPR-Cas system guide RNAs targeting genomic sequences within at least one continuous genomic region, wherein the guide RNAs target at least 100 genomic sequences upstream of a PAM sequence for every 1000 base pairs within the continuous genomic region and methods for their use.
FILED Wednesday, November 08, 2017
APPL NO 15/807007
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/102 (20130101)
C12N 15/1075 (20130101)
C12N 15/1079 (20130101) Original (OR) Class
C12N 15/1082 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685923 Jaffrey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Mental Health (NIMH)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Samie R. Jaffrey (New York, New York);  Kate D. Meyer (Durham, North Carolina)
ABSTRACT The present invention relates to methods and a kit for enhancing the translation ability of an RNA molecule. The methods involve the use of an RNA molecule comprising a methylated adenosine residue in a 5′ untranslated region (UTR). Also disclosed are methods for eIF4E-independent translation of an RNA molecule and treatment methods.
FILED Wednesday, February 19, 2020
APPL NO 16/795216
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/67 (20130101) Original (OR) Class
C12N 2310/333 (20130101)
C12N 2740/16043 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)
C12P 21/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685924 Chang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Howard Y. Chang (Stanford, California);  Chun-Kan Chen (Stanford, California)
ABSTRACT Provided herein are recombinant circular RNA (circRNA) molecules comprising an internal ribosome entry site (IRES) operably linked to a protein-coding nucleic acid sequence. The IRES includes at least one RNA secondary structure element; and a sequence region that is complementary to an 18S ribosomal RNA (rRNA). Methods of producing a protein in a cell using the recombinant circRNA molecules are also provided.
FILED Monday, October 03, 2022
APPL NO 17/937617
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/67 (20130101) Original (OR) Class
C12N 15/85 (20130101)
C12N 15/113 (20130101)
C12N 2840/203 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685954 Liu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Xiaole Liu (Wayland, Massachusetts);  Myles Brown (Boston, Massachusetts);  Wei Li (Boston, Massachusetts);  Tengfei Xiao (Shanghai, China PRC)
ABSTRACT The present invention is based on the identification of novel biomarkers predictive of endocrine resistance in breast cancer.
FILED Monday, July 10, 2017
APPL NO 16/315861
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57415 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686735 Chaiworapongsa et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Wayne State University (Detroit, Michigan);  The United States of America as Represented by the Secretary, Department of Health and Human Service (Bethesda, Maryland)
ASSIGNEE(S) WAYNE STATE UNIVERSITY (Detroit, Michigan);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
INVENTOR(S) Tinnakorn Chaiworapongsa (Grosse Pointe Park, Michigan);  Roberto Romero (Grosse Pointe, Michigan);  Sonia S. Hassan (Novi, Michigan)
ABSTRACT Provided are systems and methods for assessing the presence or risk of obstetrical complications, particularly those related to an angiogenic and anti-angiogenic imbalance. Also provided are methods of treating an angiogenic and anti-angiogenic imbalance with water-soluble statins, such as pravastatin.
FILED Wednesday, April 17, 2019
APPL NO 16/387486
ART UNIT 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/22 (20130101)
A61K 31/616 (20130101)
A61K 31/727 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/689 (20130101) Original (OR) Class
G01N 33/6872 (20130101)
G01N 2333/475 (20130101)
G01N 2333/912 (20130101)
G01N 2800/50 (20130101)
G01N 2800/368 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/40 (20180101)
G16H 20/10 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686736 Ballantyne et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Christie Mitchell Ballantyne (Houston, Texas);  Ron Hoogeveen (Houston, Texas);  Vijay Nambi (Houston, Texas);  Lloyd E. Chambless (Chapel Hill, North Carolina)
ASSIGNEE(S)
INVENTOR(S) Christie Mitchell Ballantyne (Houston, Texas);  Ron Hoogeveen (Houston, Texas);  Vijay Nambi (Houston, Texas);  Lloyd E. Chambless (Chapel Hill, North Carolina)
ABSTRACT The present disclosure relates to the field of laboratory diagnostics. Specifically, methods are disclosed for determining a patient's risk of suffering from heart failure (HF) based on the detection of NT-proBNP, troponin T, and/or a natriuretic peptide. Also disclosed are methods for improving both the accuracy and speed of HF risk models by incorporating biomarker data from patient samples.
FILED Thursday, March 15, 2018
APPL NO 15/922431
ART UNIT 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 33/6887 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 2333/58 (20130101)
G01N 2333/4712 (20130101)
G01N 2800/50 (20130101)
G01N 2800/52 (20130101)
G01N 2800/325 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686798 Roberts
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Nathan Tibbitts Roberts (Madison, Wisconsin)
ABSTRACT A system and method are provided for magnetic resonance imaging (MRI) and/or image reconstruction that includes acquiring multi-pass, chemical shift-encoded (CSE)-MRI imaging data of a subject. The method further includes performing a complex, joint estimation of phase terms in the imaging data for each pass of the multi-pass, CSE-MRI imaging data to account for concomitant gradient (CG)-induced phase errors of different passes. The method also includes generating at least one of a proton density fat fraction (PDFF) estimate or an R2* estimate that is unbiased by CG-induced phase errors using the phase terms and communicating a report that includes at least one of the PDFF estimate or the R2* estimate.
FILED Wednesday, September 29, 2021
APPL NO 17/489698
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/385 (20130101)
G01R 33/445 (20130101)
G01R 33/485 (20130101) Original (OR) Class
G01R 33/4828 (20130101)
G01R 33/5608 (20130101)
G01R 33/56518 (20130101)
G01R 33/56527 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11687790 Feinberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Evan Nathaniel Feinberg (Palo Alto, California);  Vijay Satyanand Pande (Woodside, California);  Bharath Ramsundar (Fremont, California)
ABSTRACT Systems and methods for spatial graph convolutions in accordance with embodiments of the invention are illustrated. One embodiment includes a method for predicting characteristics for molecules, wherein the method includes performing a first set of graph convolutions with a spatial graph representation of a set of molecules, wherein the first set of graph convolutions are based on bonds between the set of molecules, performing a second set of graph convolutions with the spatial graph representation, wherein the second set of graph convolutions are based on at least a distance between each atom and other atoms of the set of molecules, performing a graph gather with the spatial graph representation to produce a feature vector, and predicting a set of one or more characteristics for the set of molecules based on the feature vector.
FILED Tuesday, March 05, 2019
APPL NO 16/293586
ART UNIT 2126 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/02 (20130101)
G06N 3/08 (20130101)
G06N 3/126 (20130101) Original (OR) Class

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 15/30 (20190201)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 10/00 (20190201)
G16C 20/30 (20190201)
G16C 20/50 (20190201)
G16C 20/70 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688294 Boyce et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) UNIVERSITY OF CINCINNATI (Cincinnati, Ohio)
ASSIGNEE(S) UNIVERSITY OF CINCINNATI (Cincinnati, Ohio)
INVENTOR(S) Suzanne Boyce (Cincinnati, Ohio);  Sarah Hamilton Dugan (Dayton, Ohio);  T. Douglas Mast (Cincinnati, Ohio);  Michael Riley (Cincinnati, Ohio)
ABSTRACT Systems and methods for an enhanced ultrasound biofeedback therapy for an improved speech remediation treatment for an individual include transmitting a plurality of ultrasound (US) waves toward a tongue of the individual; receiving a plurality of reflected US waves; converting the plurality of reflected US waves into a plurality of US signals to transmit to an ultrasound machine; and generating one or more enhanced images of the tongue at least partially based on the US signals in real-time, the enhanced images including identified Regions of Interest (ROIs) along tongue sub-parts comprising the tongue root, the tongue dorsum, and the tongue blade and respective ROI points identified therein. An interactive visual story is generated and updated in real-time with a tongue-mapping trajectory of the individual on a display based on the enhanced one or more images to determine a successful or unsuccessful sound production.
FILED Friday, December 21, 2018
APPL NO 16/955120
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/085 (20130101)
A61B 8/5223 (20130101)

Image Data Processing or Generation, in General
G06T 5/002 (20130101)
G06T 7/0012 (20130101)
G06T 2207/10132 (20130101)
G06T 2207/20104 (20130101)
G06T 2207/30004 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 5/06 (20130101) Original (OR) Class
G09B 19/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688488 Westerhoff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) QuantumBio Inc. (State College, Pennsylvania)
ASSIGNEE(S) Quantumbio, Inc. (State College, Pennsylvania)
INVENTOR(S) Lance Michael Westerhoff (Annville, Pennsylvania);  Oleh Y. Borbulevych (Bellefonte, Pennsylvania);  Roger Isaac Martin (State College, Pennsylvania)
ABSTRACT An analytic method for improving the efficiency in identifying protein molecular effect information using low resolution x-ray crystallography, by selecting and imaging a protein sample with low resolution x-ray crystallography and assaying the data thus generated as to local ligand strain energy value, followed by calculating a real-space difference density Z for each element and compiling ZDD data therefrom, followed by determining the true protomer/tautomer state of the protein sample by calculating Scorei according to the following equation so that the highest Scorei signifies the molecular effect information:
Scorei={((ZDDi−μZDD)/σZDD)+((SEi−σSE)/σSE)}.
FILED Wednesday, February 26, 2020
APPL NO 16/801588
ART UNIT 1672 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/20008 (20130101)
G01N 33/6803 (20130101)
G01N 2223/304 (20130101)
G01N 2223/612 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 15/00 (20190201) Original (OR) Class
G16B 20/00 (20190201)
G16B 20/30 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688503 Kayyali et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Cleveland Medical Devices Inc. (Cleveland, Ohio)
ASSIGNEE(S) Cleveland Medical Devices Inc. (Cleveland, Ohio)
INVENTOR(S) Hani Kayyali (Shaker Heights, Ohio);  Craig A. Frederick (Solon, Ohio);  Robert N. Schmidt (Ft. Myers, Florida);  Brian M. Kolkowski (Leroy, Ohio)
ABSTRACT The various embodiments of the method of the present invention include a method to improving or expanding the capacity of a sleep analysis unit or laboratory, a method sleep analysis testing a patient admitted for diagnosis or treatment of another primary medical condition while being treated or diagnosed for that condition, a method of sleep analysis testing a patient that cannot be easily moved or treated in a sleep analysis unit or laboratory and other like methods.
FILED Monday, January 09, 2023
APPL NO 18/094539
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0004 (20130101)
A61B 5/0006 (20130101)
A61B 5/0022 (20130101)
A61B 5/087 (20130101)
A61B 5/369 (20210101)
A61B 5/486 (20130101)
A61B 5/721 (20130101)
A61B 5/4806 (20130101)
A61B 5/4815 (20130101)
A61B 5/6831 (20130101)
A61B 5/7282 (20130101)
A61B 5/14552 (20130101)
A61B 2560/0214 (20130101)
A61B 2560/0475 (20130101)
A61B 2562/0219 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101) Original (OR) Class
G16H 40/20 (20180101)
G16H 40/67 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11684597 Akingbade et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (, None)
INVENTOR(S) Katherine L. Akingbade (Silver Spring, Maryland);  Christian J. Sund (Bethesda, Maryland)
ABSTRACT A method for increasing susceptibility of microorganisms to antibiotics includes providing a microorganism; administering an antibiotic including a nitro-containing amphenicol compound to the microorganism; and administering any of an uronic, aldonic, ulosonic, and aldaric feedstock to the microorganism. The feedstock is adapted to promote cell metabolism, and inhibit antibiotic inactivation pathways in the microorganism causing increased sensitivity of the microorganism to the nitro-containing amphenicol.
FILED Monday, January 28, 2019
APPL NO 16/258780
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0056 (20130101)
A61K 31/165 (20130101)
A61K 31/191 (20130101) Original (OR) Class
A61K 31/655 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684675 Kessler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Julian Kessler (Salt Lake City, Utah);  Michael S. Yu (Salt Lake City, Utah);  Yang Li (Salt Lake City, Utah)
ABSTRACT Disclosed are peptide conjugates comprising an active agent, a spacer moiety, and a dimeric collagen hybridizing peptide comprising a first and second collagen hybridizing peptide, a linker; and a branch point, wherein the first and second collagen hybridizing peptides comprise the sequence of at least (GXY)n, wherein G is glycine, wherein X and Y are any amino acid, and wherein n is any number between 3 and 12. Also disclosed are methods of detecting denatured collagen in a sample comprising contacting a composition comprising any one of the disclosed peptide conjugates to a sample, wherein the active agent comprises a therapeutic agent, and detecting the presence or absence of binding of the peptide conjugate to denatured collagen, the presence of binding indicating the presence of denatured collagen in the sample. Also disclosed are methods of treating a disease or injury involving collagen damage comprising administering to a subject having a disease or injury involving collagen damage any one of the disclosed peptide conjugates.
FILED Wednesday, February 24, 2021
APPL NO 17/184289
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/64 (20170801)
A61K 47/65 (20170801)
A61K 47/641 (20170801) Original (OR) Class

Peptides
C07K 14/78 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6887 (20130101)
G01N 2333/78 (20130101)
G01N 2500/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684676 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Yong Zhang (Los Angeles, California);  Zhefu Dai (Los Angeles, California);  Xiao-Nan Zhang (Los Angeles, California)
ABSTRACT Antibody-drug conjugates, compositions thereof, and methods use. The antibody-drug conjugates include a fusion protein comprising an antibody covalently linked to an ADP-ribosyl cyclase protein via a peptide linker moiety at one or more of a C-terminus or N-terminus of a heavy or light chain of the antibody, a NAD or NMN analogue, and a payload such that the NAD or NMN analogue is conjugated to both the payload and the ADP-ribosyl cyclase protein.
FILED Monday, May 10, 2021
APPL NO 17/996313
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/6807 (20170801)
A61K 47/6815 (20170801) Original (OR) Class
A61K 47/6851 (20170801)
A61K 47/6889 (20170801)
A61K 2039/505 (20130101)

Peptides
C07K 16/2851 (20130101)
C07K 2317/90 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2497 (20130101)

Enzymes
C12Y 302/02006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684921 Betts et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
APPLICANT(S) Leidos, Inc. (Reston, Virginia);  Jennifer W. Sekowski (Forest Hill, Maryland)
ASSIGNEE(S) Leidos, Inc. (Reston, Virginia);  The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Kelley D. Betts (Rising Sun, Maryland);  Jennifer W. Sekowski (Forest Hill, Maryland)
ABSTRACT The pocket detection platform (PDP) detects pathogens, toxins and chemicals of interest simultaneously by way of a multi-channeled, soft see-through plastic pouch design that consists of inner and outer compartments that promote compartmentalization and/or unidirectional sample flow. The platform enables the concurrent running of multiple detection assay techniques such as lateral flow immunoassays (LFI), Isothermal molecular assays (i.e., Recombinase Polymerase Amplification, or RPA) and/or paper-based chemical assays (i.e., M8, pH paper) from a single wet or dry sample with minimal sample processing. The PDP reduces soldier overburden by decreasing size weight, and power (SWaP) as well as training time, electronic burden, while providing a flexible, customizable assay platform that can be rapidly produced, assembled, sustained, and when contaminated, easily to dispose of.
FILED Friday, August 07, 2020
APPL NO 16/988368
ART UNIT 1677 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101) Original (OR) Class
B01L 2200/10 (20130101)
B01L 2200/027 (20130101)
B01L 2200/0689 (20130101)
B01L 2300/04 (20130101)
B01L 2300/123 (20130101)
B01L 2300/126 (20130101)
B01L 2300/0636 (20130101)
B01L 2300/0809 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/02 (20130101)
G01N 33/5302 (20130101)
G01N 2001/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685892 Rao et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland)
ASSIGNEE(S) University of Maryland, Baltimore County (Baltimore, Maryland)
INVENTOR(S) Govind Rao (Ellicott City, Maryland);  Yordan Kostov (Columbia, Maryland);  Benjamin Punshon-Smith (Gwynn Oak, Maryland);  Rajani Adiga (Laurel, Maryland)
ABSTRACT The present invention relates to cell free protein manufacturing, and more particularly, for integrating machine learning into a portable cell-free bioprocessing system for producing proteins with increased and consistent purity, potency and quality wherein such proteins are prepared on-demand and for point-of-care delivery.
FILED Wednesday, May 15, 2019
APPL NO 17/055149
ART UNIT 1799 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/54 (20130101)
C12M 41/48 (20130101) Original (OR) Class
C12M 47/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685934 Walter
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Amyris, Inc. (Emeryville, California)
ASSIGNEE(S) Amyris, Inc. (Emeryville, California)
INVENTOR(S) Jessica Walter (Albany, California)
ABSTRACT The present invention provides high efficiency targeted and marker-less single or simultaneous multiple integrations using nucleases and a stable plasmid in Kluyveromyces host cells.
FILED Wednesday, September 12, 2018
APPL NO 16/646028
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/815 (20130101)
C12N 15/905 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685954 Liu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Xiaole Liu (Wayland, Massachusetts);  Myles Brown (Boston, Massachusetts);  Wei Li (Boston, Massachusetts);  Tengfei Xiao (Shanghai, China PRC)
ABSTRACT The present invention is based on the identification of novel biomarkers predictive of endocrine resistance in breast cancer.
FILED Monday, July 10, 2017
APPL NO 16/315861
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57415 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686202 Molnar, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana)
INVENTOR(S) Daniel E. Molnar, Jr. (Lebanon, Indiana)
ABSTRACT A rotor assembly for a gas turbine engine includes a rotor extending circumferentially about a central axis. The rotor includes a ring that extends around the central axis and a mount that extends axially away from the ring. The ring includes an axially facing engagement surface. A blade extends radially outward from the ring of the rotor. A damper is coupled with the mount of the rotor and engaged with the engagement surface to minimize vibrations of the rotor assembly.
FILED Monday, December 20, 2021
APPL NO 17/557025
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/10 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/60 (20130101)
F05D 2240/24 (20130101)
F05D 2260/96 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686211 Hall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Rolls-Royce Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S) Christopher D. Hall (Danville, Indiana);  William B. Bryan (Indianapolis, Indiana);  Daniel E. Molnar, Jr. (Lebanon, Indiana)
ABSTRACT A fan assembly includes a fan duct, an inlet fan, and an outlet guide vane assembly. The inlet fan forces fan exit air toward an aft end of the fan duct. The outlet guide vane assembly is located in the fan duct downstream of the inlet fan and adjusts a direction of the fan exit air, and includes a plurality of outlet guide vanes and a plurality of actuation assemblies that control rotation of the outlet guide vanes about a pitch axis. The outlet guide vanes include a leading edge portion and a trailing edge portion rotatably coupled to an axially aft edge of the leading edge portion. The actuation assembly rotates the leading edge portion and the trailing edge portion to minimize losses created by distortions in fan inlet air and created by the leading edge portion redirecting the fan exit air in the first direction.
FILED Wednesday, August 25, 2021
APPL NO 17/412222
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 17/08 (20130101)
F01D 17/162 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2240/12 (20130101)
F05D 2270/10 (20130101)
F05D 2270/102 (20130101)
F05D 2270/301 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686510 Chester et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Mainstream Engineering Corporation (Rockledge, Florida)
ASSIGNEE(S) Mainstream Engineering Corporation (Rockledge, Florida)
INVENTOR(S) Gregory E. Chester (Rockledge, Florida);  Ryan D. Reeves (Melbourne, Florida);  Justin J. Hill (Rockledge, Florida)
ABSTRACT A process is disclosed for cooling a material that includes semiconductor nanoparticles in matrix material by anti-Stokes up-conversion. The semiconductor nanoparticle matrix is irradiated by a laser with a photonic wavelength matched to the anti-Stokes photoluminescence of the semiconductor nanoparticle bandgap. The semiconductor nanoparticles absorb the laser photon and phonons (heat) from lattice vibrations to photoluminescence photons with higher energy than the photon that were absorbed. A net cooling effect is generated from the lower energy and lower temperature in the material after anti-Stoke up-conversion.
FILED Friday, October 29, 2021
APPL NO 17/514038
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 23/003 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 6/262 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686627 Roth, II et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Naval Air Warfare Center (NAWC)
APPLICANT(S) Etegent Technologies LTD. (Cincinnati, Ohio)
ASSIGNEE(S) ETEGENT TECHNOLOGIES LTD. (Cincinnati, Ohio)
INVENTOR(S) Richard A. Roth, II (Goshen, Ohio);  Stuart J. Shelley (Cincinnati, Ohio);  Kevin Sigmund (Newtown, Ohio);  Oleg Lobkis (Mason, Ohio)
ABSTRACT An active mechanical waveguide including an ultrasonically-transmissive material and a plurality of reflection points defined along a length of the waveguide may be driven at multiple resonant frequencies to sense environmental conditions, e.g., using tracking of a phase derivative. In addition, frequency-dependent reflectors may be incorporated into an active mechanical waveguide, and a drive frequency may be selected to render the frequency-dependent reflectors substantially transparent.
FILED Tuesday, April 10, 2018
APPL NO 16/604426
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 11/24 (20130101) Original (OR) Class

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/10 (20130101)
G01L 11/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/42 (20130101)
G01N 29/44 (20130101)
G01N 29/075 (20130101)
G01N 29/4454 (20130101)
G01N 2291/044 (20130101)

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/24 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 3/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686770 Dickens
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) GRAMMATECH, INC. (Ithaca, New York)
ASSIGNEE(S) GRAMMATECH INC. (Ithaca, New York)
INVENTOR(S) Jason Alvin Dickens (Newfield, New York)
ABSTRACT Systems, methods, and computer readable medium described herein relate to techniques for characterizing and/or anomaly detection in integrated circuits such as, but not limited to, field programmable gate arrays (FPGAs) and application-specific integrated circuits (ASICs). In one example aspect of certain example embodiments, a fully digital technique relies on the pulse width of signals propagated through a path under test. In another example aspect, the re-configurability of the integrated circuit is leveraged to combine the pulse propagation technique with a delay characterization technique to yield better detection of certain type of Trojans and the like. Another example aspect provides for running the test through reconfigurable path segments in order to isolate and identify anomalous circuit elements. Yet another example aspect provides for performing the characterization and anomaly detection without requiring golden references and the like.
FILED Monday, August 09, 2021
APPL NO 17/397417
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/3177 (20130101)
G01R 31/31706 (20130101)
G01R 31/31725 (20130101)
G01R 31/318519 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11687148 Montoye et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Robert K. Montoye (Yorktown Heights, New York);  Kevin Tien (Trumbull, Connecticut);  Yutaka Nakamura (Kyoto, Japan);  Jeffrey Haskell Derby (Chapel Hill, North Carolina);  Martin Cochet (South Salem, New York);  Todd Edward Takken (Brewster, New York);  Xin Zhang (Chappaqua, New York)
ABSTRACT A system and method for supporting an interconnection of processor cores, each core with functional state monitors for monitoring operations of each processor core, the processor cores interconnected using a resistive network connected between two-terminal regions being embedded in the resistive network such that each terminal of a region may be connected by controllable resistors to one or both fixed rails or by controllable resistors to one or more intermediate nodes. The resistor values are configurable to provide indirect control of the voltages across each two-terminal region, allowing full dynamic control of voltages of the two-terminal regions in a range up to the full voltage between the two voltage rails, and where a management unit accesses the functional state monitors and controls the resistor values. Feedback from functional state monitors allow the operating frequency to extend down to arbitrarily low values and up to the limits imposed by the technology.
FILED Tuesday, April 26, 2022
APPL NO 17/729638
ART UNIT 2186 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 1/324 (20130101)
G06F 1/3296 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11687619 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Robert Bosch GmbH (Stuttgart, Germany)
ASSIGNEE(S) ROBERT BOSCH GMBH (Stuttgart, Germany)
INVENTOR(S) Xiao Zhang (Charlottesville, Virginia);  Anit Kumar Sahu (Pittsburgh, Pennsylvania);  Jeremy Kolter (Pittsburgh, Pennsylvania)
ABSTRACT A computer-program product storing instructions which, when executed by a computer, cause the computer to receive an input data from a sensor, wherein the input data includes data indicative of an image, wherein the sensor includes a video, radar, LiDAR, sound, sonar, ultrasonic, motion, or thermal imaging sensor, generate an adversarial version of the input data, utilizing a generator, in response to the input data, create a training data set utilizing the input data and the adversarial version of the input data, determine an update direction of a meta model utilizing stochastic gradient respect with respect to an adversarial loss, and determine a cross-entropy based classification loss in response to the input data and classification utilizing a classifier, and update the meta model and the classifier in response to the cross-entropy classification loss utilizing the training data set.
FILED Friday, October 02, 2020
APPL NO 17/062385
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 18/2148 (20230101) Original (OR) Class
G06F 18/2185 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/02 (20130101)
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688539 Levy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Jeremy Levy (Pittsburgh, Pennsylvania);  Feng Bi (Pittsburgh, Pennsylvania);  Patrick R. Irvin (Allison Park, Pennsylvania)
ABSTRACT A structure includes an electronically controllable ferromagnetic oxide structure that includes at least three layers. The first layer comprises STO. The second layer has a thickness of at least about 3 unit cells, said thickness being in a direction substantially perpendicular to the interface between the first and second layers. The third layer is in contact with either the first layer or the second layer or both, and is capable of altering the charge carrier density at the interface between the first layer and the second layer. The interface between the first and second layers is capable of exhibiting electronically controlled ferromagnetism.
FILED Monday, November 22, 2021
APPL NO 17/533044
ART UNIT 1785 — Miscellaneous Articles, Stock Material
CURRENT CPC
Static Stores
G11C 11/155 (20130101)
G11C 11/161 (20130101)
G11C 11/1675 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/40 (20130101)
H01F 10/06 (20130101)
H01F 10/193 (20130101)
H01F 10/3213 (20130101)
H01F 13/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688593 Schmitt et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Spark Thermionics, Inc. (Berkeley, California)
ASSIGNEE(S) Spark Thermionics, Inc. (Berkeley, California)
INVENTOR(S) Felix Schmitt (Berkeley, California);  Jared William Schwede (Berkeley, California);  Adam Lorimer (Berkeley, California)
ABSTRACT A system for thermionic energy generation, preferably including one or more thermionic energy converters, and optionally including one or more power inputs, airflow modules, and/or electrical loads. A thermionic energy converter, preferably including an emitter module, a collector module, and/or a seal, and optionally including a spacer. The thermionic energy converter preferably defines a chamber and/or a heating cavity. A method for thermionic energy generation, preferably including receiving power, emitting electrons, and/or receiving the emitted electrons, and optionally including convectively transferring heat.
FILED Friday, July 15, 2022
APPL NO 17/866381
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 45/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688599 Lindstrom et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico)
ASSIGNEE(S) Government of the United States of America as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico)
INVENTOR(S) Chadwick Lindstrom (Albuquerque, New Mexico);  John Ballenthin (Albuquerque, New Mexico);  David Barton (Los Ranchos, New Mexico);  Joseph Coombs (Albuquerque, New Mexico);  Scott Kratochvil (Albuquerque, New Mexico);  David Stiles (Albuquerque, New Mexico);  Adrian Wheelock (Albuquerque, New Mexico);  Stephen Quigley (Albuquerque, New Mexico);  Patrick Roddy (Albuquerque, New Mexico);  Richard Selesnick (Albuquerque, New Mexico)
ABSTRACT An environmental sensor may acquire data related to flux and energy of charged particles in an environment for using the data to determine, in substantially real time, whether the environment is conducive to an anomaly caused by the charged particles. The sensor may include an electrostatic analyzer structurally configured for charged particle detection, the electrostatic analyzer generating controllable electric fields to provide energy filtering of incoming charged particles, where, after filtering, the charged particles impact a charge multiplier to establish a detectable signal. The sensor may further include a plurality of silicon detector telescopes structurally configured to collectively detect electrons having energy within the range of about 100 electronvolts (eV) to about 5 mega-electronvolts (MeV) and to collectively detect protons having energy within the range of about 2 MeV to about 100 MeV.
FILED Tuesday, December 18, 2018
APPL NO 16/223471
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/05 (20130101)
H01J 37/244 (20130101)
H01J 37/261 (20130101)
H01J 49/48 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688638 Chan et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) SRI International (Menlo Park, California)
ASSIGNEE(S) SRI International (Menlo Park, California)
INVENTOR(S) Winston K. Chan (Princeton, New Jersey);  Joey J. Michalchuk (Lambertville, New Jersey)
ABSTRACT A system to manufacture a plurality of dies may include an etching tool, an electrically-conductive-adhesive-composition, a heat-applying-extraction-tool and a porous substrate cooperating with an evacuation component. The etching tool uses an ion beam that is configured to singulate a plurality of dies on a wafer with an ion etching process. The electrically-conductive-adhesive-composition is located between the wafer and a porous substrate carrying the wafer during the ion etching process. The electrically-conductive-adhesive-composition adheres the wafer to the porous substrate to keep the dies in place during the ion etching process. The electrically-conductive-adhesive-composition also aids in conducting electrons away from the wafer as a drain during the ion etching process. The heat-applying-extraction-tool applies heat to an individual die during a handling process of the manufacturing process in order to melt the electrically-conductive-adhesive-composition through the porous substrate to an evacuation component in order to then pick up an individual die singulated from the wafer.
FILED Tuesday, March 27, 2018
APPL NO 16/497113
ART UNIT 2899 — Semiconductors/Memory
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 43/006 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 2003/085 (20130101)
C08K 2003/0806 (20130101)
C08K 2003/0831 (20130101)
C08K 2201/001 (20130101)

Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives
C09J 9/02 (20130101)
C09J 11/04 (20130101)
C09J 191/06 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/78 (20130101) Original (OR) Class
H01L 21/6835 (20130101)
H01L 21/67092 (20130101)
H01L 29/0657 (20130101)
H01L 2221/68327 (20130101)
H01L 2221/68381 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688756 Goldstein et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Jordan Goldstein (Cambridge, Massachusetts);  Dirk Robert Englund (Brookline, Massachusetts)
ABSTRACT A filter-based color imaging array that resolves N different colors detects only 1/Nth of the incoming light. In the thermal infrared wavelength range, filtering loss is exacerbated by the lower sensor detectivity at infrared wavelengths than at visible wavelengths. To avoid loss due to filtering, most spectral imagers use bulky optics, such as diffraction gratings or Fourier transform interferometers, to resolve different colors. Fortunately, it is possible to avoid filtering loss without bulky optics: detect light with interleaved arrays of sub-wavelength-spaced antennas tuned to different wavelengths. An optically sensitive element inside each antenna absorbs light at the antenna's resonant wavelength. Metallic slot antennas offer high efficiency, intrinsic unidirectionality, and lower cross-talk than dipole or bowtie antennas. Graphene serves at the optically active material inside each antenna because its 2D nature makes it easily adaptable to this imager architecture.
FILED Friday, November 15, 2019
APPL NO 16/684917
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/2004 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/14649 (20130101) Original (OR) Class
H01L 29/1606 (20130101)

Antennas, i.e Radio Aerials
H01Q 21/064 (20130101)

Pictorial Communication, e.g Television
H04N 5/33 (20130101)

Electric solid-state devices not otherwise provided for
H10N 19/00 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11689223 Aspuru-Guzik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Alan Aspuru-Guzik (Cambridge, Massachusetts);  Jonathan P. Olson (Cambridge, Massachusetts);  Jhonathan Romero Fontalvo (Cambridge, Massachusetts);  Peter D. Johnson (Cambridge, Massachusetts);  Yudong Cao (Cambridge, Massachusetts);  Pierre-Luc Dallaire-Demers (Cambridge, Massachusetts)
ABSTRACT Model-free error correction in quantum processors is provided, allowing tailoring to individual devices. In various embodiments, a quantum circuit is configured according to a plurality of configuration parameters. The quantum circuit comprises an encoding circuit and a decoding circuit. Each of a plurality of training states is input to the quantum circuit. The encoding circuit is applied to each of the plurality of training states and to a plurality of input syndrome qubits to produce encoded training states. The decoding circuit is applied to each of the encoded training states to determine a plurality of outputs. A fidelity of the quantum circuit is measured for the plurality of training states based on the plurality of outputs. The fidelity is provided to a computing node. The computing node determines a plurality of optimized configuration parameters. The optimized configuration parameters maximize the accuracy of the quantum circuit for the plurality of training states.
FILED Friday, September 14, 2018
APPL NO 16/647188
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)
G06N 10/70 (20220101)
G06N 20/00 (20190101)

Coding; Decoding; Code Conversion in General
H03M 13/1575 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11689821 Divitt et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Shawn Divitt (Gaithersburg, Maryland);  Samuel Park (McLean, Virginia)
ABSTRACT An Incoherent Fourier ptychographic imaging system. Multiple known light patterns are projected sequentially onto a target and images of the combined pattern and target are recorded by a camera, with the images being processed using an optical transfer function (OTF). The camera and projection system are aligned along the same optical axis. The known illumination patterns and the optical transfer function (OTF) are combined in an iterative algorithm to generate an image with resolution greater than would be achieved by uniform illumination of the target and imaging with the camera.
FILED Tuesday, July 27, 2021
APPL NO 17/386005
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Pictorial Communication, e.g Television
H04N 5/265 (20130101)
H04N 23/56 (20230101)
H04N 23/951 (20230101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11690090 Learned
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Rachel E. Learned (Waltham, Massachusetts)
ABSTRACT In some embodiments, a method for mitigating interference in a channel having multiple users includes: transmitting, by a transmitter, a signal of interest (SOI) to a sequential interference cancellation (SIC) receiver at a transmit power; determining a packet drop rate as seen by the receiver; and decreasing the transmit power in response to determining the packet drop rate exceeds a predetermined maximum packet drop rate. The transmitter's coding rate and/or modulation level may also be lowered based on the decrease in transmit power.
FILED Thursday, May 21, 2020
APPL NO 16/880410
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission
H04B 1/7103 (20130101)
H04B 7/086 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0048 (20130101)
H04L 25/0204 (20130101)

Wireless Communication Networks
H04W 52/241 (20130101)
H04W 52/367 (20130101)
H04W 72/541 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11690160 Eden et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) J. Gary Eden (Mahomet, Illinois);  Peng Sun (Savoy, Illinois);  Wenyuan Chen (Champaign, Illinois);  Yin Huang (Urbana, Illinois)
ABSTRACT The invention provides a microplasma photonic crystal for reflecting, transmitting and/or storing incident electromagnetic energy includes a periodic array of elongate microtubes confining microplasma therein and having a column-to-column spacing, average electron density and plasma column diameter selected to produce a photonic response to the incident electromagnetic energy entailing the increase or suppression of crystal resonances and/or shifting the frequency of the resonances. The crystal also includes electrodes for stimulating microplasma the elongated microtubes Electromagnetic energy can be interacted with the periodic array of microplasma to reflect, transmit and/or trap the incident electromagnetic energy.
FILED Friday, September 04, 2020
APPL NO 17/012539
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/2406 (20130101) Original (OR) Class
H05H 1/2431 (20210501)
H05H 1/2437 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11690295 Taylor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Patrick J. Taylor (Oakton, Virginia);  Jay R. Maddux (Greenbelt, Maryland);  Kimberly A. Olver (Ellicot City, Maryland);  Sina Simingalam (McLean, Virginia)
ABSTRACT Protective coating to prevent sublimation are disclosed. More particularly, the protective coatings comprise one or more alkaline earth halide materials, or mixtures thereof, to prevent sublimation. The alkaline earth halide material of the coating can be judiciously selected to match the coefficient of thermal expansion (CTE) of the material of the external surface of the underlying substrate coated. The protective coatings may be advantageous for protecting external surfaces of thermoelectric materials, parts and devices at high temperature to prevent sublimation and material loss.
FILED Monday, June 15, 2020
APPL NO 16/901138
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 35/10 (20130101)
H01L 35/32 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11684284 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
NIH Office of the Director (NIHOD)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Jin Hyung Lee (Stanford, California);  Ben A. Duffy (Palo Alto, California)
ABSTRACT The present disclosure provides a device for carrying out magnetic resonance imaging compatible optogenetics; and methods for using the device.
FILED Wednesday, July 20, 2016
APPL NO 15/743174
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class
A61B 5/0084 (20130101)
A61B 5/4041 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/05 (20130101)
A61N 1/086 (20170801)
A61N 5/067 (20210801)
A61N 5/0622 (20130101)
A61N 2005/063 (20130101)
A61N 2005/0651 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684295 Kivi et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Storx Technologies, Inc. (Davis, California)
ASSIGNEE(S) Storx Technologies, Inc. (Davis, California)
INVENTOR(S) Golnaz Alipour Kivi (San Diego, California);  Soheil Ghiasihafezi (Davis, California)
ABSTRACT Systems and methods are described, and one method includes determining a fetal blood oxygenation level, including: activating at least one light source with at least two distinct wavelengths of light on an abdomen of a pregnant mammal to direct light into a maternal abdomen toward a fetus; receiving a set of mixed signals from a set of photodetectors positioned at different locations on the maternal abdomen from reflected light that traverses maternal tissue or maternal tissue and fetal tissue; determining the fetal blood oxygenation level by performing computations on a composite fetal signal produced from the mixed signals; and ensuring a skin temperature of the maternal abdomen does not rise to unsafe levels due to activating the at least one light source.
FILED Wednesday, November 25, 2020
APPL NO 17/104654
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/0064 (20130101)
A61B 5/725 (20130101)
A61B 5/02411 (20130101)
A61B 5/4362 (20130101)
A61B 5/6823 (20130101)
A61B 5/14542 (20130101) Original (OR) Class
A61B 2562/0271 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684536 Kazerooni et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Homayoon Kazerooni (Berkeley, California);  Mimi Parker (Berkeley, California);  Lace Co Ting Keh (La Crescenta, California)
ABSTRACT A fall prevention device configured to be coupled to a person and comprising a mechanical torso configured to be coupled to the person's torso and a mechanical structure configurable to be coupled to the mechanical torso from its first end. The mechanical structure and mechanical torso resist forces at least along one direction to maintain their posture relative to each other. In operation the second end of the mechanical structure is positioned behind the person and substantially close to the ground. When the second end of the mechanical structure contacts the ground, contact points of legs of the person on the ground and contact points of the second end of the mechanical structure outline a multi-sided polygon on the ground. If the vertical projection of the center of gravity of the person to the ground intersects the ground within the multi-sided polygon, the person and fall prevention device remain stable.
FILED Tuesday, November 13, 2018
APPL NO 16/189809
ART UNIT 3786 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/70 (20130101)
A61F 2002/701 (20130101)
A61F 2002/704 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 3/00 (20130101)
A61H 3/04 (20130101)
A61H 3/008 (20130101) Original (OR) Class
A61H 2003/007 (20130101)
A61H 2201/0161 (20130101)
A61H 2201/163 (20130101)
A61H 2201/165 (20130101)
A61H 2201/0192 (20130101)
A61H 2201/1616 (20130101)
A61H 2201/1642 (20130101)
A61H 2201/1652 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684681 Pease et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah)
INVENTOR(S) Leonard F. Pease (Salt Lake City, Utah);  Hedieh Saffari (Salt Lake City, Utah);  Gerald J. Gleich (Salt Lake City, Utah);  Kristin M. Leiferman (Salt Lake City, Utah);  Kathryn A. Peterson (Salt Lake City, Utah);  Russell Morris Condie (Salt Lake City, Utah)
ABSTRACT Disclosed are methods of detecting eosinophil degranulation in the respiratory tract of subjects. Also, disclosed are methods of producing medical images of the respiratory tract of subjects. The method can include administering radiolabeled heparin to the respiratory tract of subjects, wherein the radiolabeled heparin binds to one or more eosinophil granule protein in the mucosal tissue of the respiratory tract.
FILED Monday, July 19, 2021
APPL NO 17/379402
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/08 (20130101)
A61K 51/0491 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684780 Song et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Dong Song (Walnut, California);  Theodore W. Berger (Rancho Palos Verdes, California);  Sahar Elyahoodayan (Los Angeles, California)
ABSTRACT A method for providing stimulation of living tissue may include generating electrical pulses onto multiple output channels to a plurality of electrodes each corresponding to one of the multiple output channels. The method may also include disconnecting the plurality of electrodes from recording amplifiers during a stimulation. Additionally, the method may include shorting, after each stimulation before recording is resumed, inputs of the recording amplifiers to ground to suppress ringing in the recording system.
FILED Thursday, October 17, 2019
APPL NO 16/656478
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36082 (20130101)
A61N 1/36125 (20130101)
A61N 1/36128 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684894 Jeong et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Texas A and M University (College Station, Texas)
ASSIGNEE(S) Texas A and M University (College Station, Texas)
INVENTOR(S) Hae-Kwon Jeong (College Station, Texas);  Mohamad Rezi Abdul Hamid (Perak, Malaysia)
ABSTRACT Provided herein are in situ methods for fabricating a mixed-matrix membrane or a mixed-matrix hollow fiber membrane for increasing formation of zeolitic imidazolate framework nanoparticles inside the mixed-matrix membrane. Generally, in the method a polyimide polymer coated onto at least one support is hydrolzed with a base and the poly(amic acid)-salt film formed thereby undergoes ion exchange with a metal ion, treatment of the formed poly(amic acid)-metal salt film with an organic linker to produce metal-organic framework nanoparticles in situ, and imidization of the treated poly(amic acid)-metal salt film produces a polyimide/metal-organic framework mixed-matrix membrane or a mixed-matrix hollow fiber membrane module. Also provided is the mixed-matrix membrane and the polymer mixed-matrix hollow fiber membrane module fabricated by the methods and methods for separating a binary gas mixture via the fabricated mixed-matrix membrane.
FILED Monday, October 26, 2020
APPL NO 17/080291
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/228 (20130101)
B01D 63/023 (20130101)
B01D 67/0079 (20130101) Original (OR) Class
B01D 69/148 (20130101)
B01D 71/028 (20130101)
B01D 71/64 (20130101)
B01D 2323/36 (20130101)
B01D 2323/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684989 Romanelli et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) IHT Automation GmbH and Co. KG (Baden-Baden, Germany);  The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) IHT Automation GmbH and Co. KG (Baden-Baden, Germany);  The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Giuseppe Romanelli (Buehl, Germany);  Marcel Biskaborn (Oberkirch, Germany);  Christopher Reed Martin (Hollidaysburg, Pennsylvania)
ABSTRACT A method for monitoring a flame cutting process includes a preheating phase, a piercing phase following the preheating phase and a cutting phase following the piercing phase, wherein a cutting torch applies a flame generated by combustion of a gas mixture to an electrically conductive workpiece and wherein an electric current flowing between an electrically conductive part of the cutting torch and the workpiece is measured by a current measuring device during a measuring period. An ignition point at which piercing of a hole through the workpiece using the flame starts due to oxidation of the workpiece is detected by a change in the measured current.
FILED Tuesday, July 06, 2021
APPL NO 17/367857
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 7/102 (20130101) Original (OR) Class

Burners
F23D 14/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685270 Karalis et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MIT (Cambridge, Massachusetts)
INVENTOR(S) Aristeidis Karalis (Boston, Massachusetts);  Andre B. Kurs (Chestnut Hill, Massachusetts);  Robert Moffatt (Reston, Virginia);  John D. Joannopoulos (Belmont, Massachusetts);  Peter H. Fisher (Cambridge, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT Disclosed is an apparatus for use in wireless energy transfer, which includes a first resonator structure configured to transfer energy non-radiatively with a second resonator structure over a distance greater than a characteristic size of the second resonator structure. The non-radiative energy transfer is mediated by a coupling of a resonant field evanescent tail of the first resonator structure and a resonant field evanescent tail of the second resonator structure.
FILED Tuesday, September 01, 2020
APPL NO 17/009041
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 53/126 (20190201) Original (OR) Class
B60L 2210/20 (20130101)

Antennas, i.e Radio Aerials
H01Q 7/00 (20130101)
H01Q 9/04 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/12 (20160201)
H02J 50/80 (20160201)
H02J 50/90 (20160201)

Transmission
H04B 5/0037 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/70 (20130101)
Y02T 10/72 (20130101)
Y02T 10/7072 (20130101)
Y02T 90/12 (20130101)
Y02T 90/14 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/4902 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685271 Joannopoulos et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) John D. Joannopoulos (Belmont, Massachusetts);  Aristeidis Karalis (Boston, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT Described herein are embodiments of a source high-Q resonator, optionally coupled to an energy source, a second high-Q resonator, optionally coupled to an energy drain that may be located a distance from the source resonator. A third high-Q resonator, optionally coupled to an energy drain that may be located a distance from the source resonator. The source resonator and at least one of the second resonator and third resonator may be coupled to transfer electromagnetic energy from said source resonator to said at least one of the second resonator and third resonator.
FILED Tuesday, August 31, 2021
APPL NO 17/462126
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 53/126 (20190201) Original (OR) Class

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 38/14 (20130101)

Antennas, i.e Radio Aerials
H01Q 9/04 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/12 (20160201)
H02J 50/40 (20160201)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/70 (20130101)
Y02T 10/7072 (20130101)
Y02T 90/12 (20130101)
Y02T 90/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685741 Guo
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Maolin Guo (Dartmouth, Massachusetts)
ABSTRACT The present disclosure relates to compounds of Formula I, II, or III and compositions of the same, which are reversible off-on or ratiometric fluorescent iron sensors and are useful in live-cell imaging of labile iron ions and their quantification in subcellular compartments, as well as treatment of diseases associated with iron dyshomoestasis.
FILED Thursday, February 01, 2018
APPL NO 16/485469
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 491/22 (20130101)
C07D 491/107 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/643 (20130101)
G01N 33/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685797 Pyun et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Dong-Chul Pyun (Tucson, Arizona);  Robert A. Norwood (Tucson, Arizona);  Roland Himmelhuber (Tucson, Arizona);  Tristan Stephen Kleine (Tuscon, Arizona);  Liliana Ruiz Diaz (Tuscon, Arizona);  Laura E. Anderson (Tuscon, Arizona)
ABSTRACT The present invention provides certain polymeric materials, precursors thereof as well as the preparation and uses thereof.
FILED Thursday, March 29, 2018
APPL NO 16/499689
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 329/10 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 112/30 (20200201) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 1/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686007 Majumdar et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) New Mexico Tech University Research Park Corporation (Socorro, New Mexico)
ASSIGNEE(S) NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION (Socorro, New Mexico)
INVENTOR(S) Bhaskar S. Majumdar (Socorro, New Mexico);  Sherin Bhassyvasantha (Socorro, New Mexico);  Luke Soule (Albuquerque, New Mexico)
ABSTRACT The disclosure provides a Sn—In electroplating bath that is Pb-free, environmentally safe, operates at room temperature, and does not require changes in existing plating assemblies. Room temperature aging and limited thermal cycling tests show that the electroplated Sn—In alloy film on a Cu substrate effectively mitigates whisker growth.
FILED Friday, December 14, 2018
APPL NO 16/220883
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/31 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/30 (20130101)
C25D 3/32 (20130101)
C25D 3/60 (20130101) Original (OR) Class
C25D 17/10 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 3/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686097 Blundo et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Tyler Blundo (Ringwood, New Jersey);  Christiana Honsberg (Tempe, Arizona);  Stephen Goodnick (Fort McDowell, Arizona);  Richard King (Tempe, Arizona);  Nicholas Irvin (Phoenix, Arizona)
ABSTRACT A skylight for a building includes a solar panel arranged within the skylight, the solar panel comprising one or more photovoltaic cells to collect direct radiation from rays of sunlight for conversion to electrical power, and an optical element to receive the direct radiation and refract it to the solar panel, and to receive the direct radiation and diffuse radiation scattered from the rays of sunlight and refract the direct radiation and the diffuse radiation through the skylight, bypassing the solar panel, to provide daylighting in the building.
FILED Monday, November 23, 2020
APPL NO 17/102191
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Roof Coverings; Sky-lights; Gutters; Roof-working Tools
E04D 13/033 (20130101) Original (OR) Class

Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates
E06B 9/24 (20130101)
E06B 2009/2417 (20130101)
E06B 2009/2494 (20130101)

Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors
F21S 11/002 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/32 (20130101)
G02B 5/208 (20130101)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 20/26 (20141201)
H02S 40/22 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686729 Ramasamy et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) Ramaraja P. Ramasamy (Watkinsville, Georgia);  Yan Zhou (Athens, Georgia)
ABSTRACT The present disclosure includes methods and systems of detecting bacteria in a sample using phage-functionalized sensors, methods of enriching a sample with phage-functionalized magnetic particles, phage-functionalized magnetic particles and methods of making phage-functionalized magnetic particles.
FILED Wednesday, November 29, 2017
APPL NO 16/464645
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2795/10131 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/554 (20130101)
G01N 33/5438 (20130101)
G01N 33/54326 (20130101)
G01N 33/56911 (20130101) Original (OR) Class
G01N 2333/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686933 Zheng
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Connecticut (Farmington, Connecticut)
ASSIGNEE(S) University of Connecticut (Farmington, Connecticut)
INVENTOR(S) Guoan Zheng (Vernon, Connecticut)
ABSTRACT An imaging system includes a sample mount for holding a sample to be imaged, a light source configured to emit a light beam to be incident on the sample, a translation mechanism coupled to the sample mount and configured to scan the sample to a plurality of sample positions in a plane substantially perpendicular to an optical axis of the imaging system, a mask positioned downstream from the sample along the optical axis, and an image sensor positioned downstream from the mask along the optical axis. The image sensor is configured to acquire a plurality of images as the sample is translated to the plurality of sample positions. Each respective image corresponds to a respective sample position. The imaging system further includes a processor configured to process the plurality of images to recover a complex profile of the sample based on positional shifts extracted from the plurality of images.
FILED Friday, September 16, 2022
APPL NO 17/946833
ART UNIT 2425 — Cable and Television
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2806 (20130101)
G01N 15/10 (20130101)
G01N 2015/1493 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/36 (20130101)
G02B 21/367 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11687230 Krishnamurthy et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Vinayak Raman Krishnamurthy (West Lafayette, Indiana);  Cecil Piya (West Lafayette, Indiana);  Karthik Ramani (West Lafayette, Indiana)
ABSTRACT Some examples provides a set of frameworks, process and methods aimed at enabling the expression and exploration of free-form and parametric 3D shape designs enabled through natural interactions with a hand-held mobile device acting as a controller for 3D virtual objects. A reference plane in a virtual space generated by the location of the mobile device may be used to select a 3D virtual object intersected by the reference plane. Positioning of the mobile device may also be used to control a pointer in the virtual space. In an example, the orientation of the mobile device may be detected by an accelerometer or gyroscope. In example, the position of the mobile device may be detected by a position sensor.
FILED Monday, January 10, 2022
APPL NO 17/571651
ART UNIT 2694 — Selective Visual Display Systems
CURRENT CPC
Electric Digital Data Processing
G06F 3/017 (20130101)
G06F 3/0346 (20130101)
G06F 3/04845 (20130101)
G06F 3/04883 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 19/006 (20130101)
G06T 19/20 (20130101)
G06T 2219/2016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11687333 Cai et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Drexel University (Philadelphia, Pennsylvania);  University of Hawaii (Honolulu, Hawaii)
ASSIGNEE(S) Drexel University (Philadelphia, Pennsylvania);  University of Hawaii (Honolulu, Hawaii)
INVENTOR(S) Yuanfang Cai (Paoli, Pennsylvania);  Ran Mo (Philadelphia, Pennsylvania);  Frederick Kazman (Pittsburgh, Pennsylvania)
ABSTRACT Enabling quick feature delivery is essential for product success and is therefore a goal of software architecture design. But how may we determine if and to what extent an architecture is “good enough” to support feature addition and modification, or determine if a refactoring effort is successful in that features may be added more easily? The applications may use Feature Space and Feature Dependency, derived from a software project's revision history that capture the dependency relations among the features of a system in a feature dependency structure matrix (FDSM), using features as first-class design elements. The applications may also use a Feature Decoupling Level (FDL) metric that may be used to measure the level of independence among features.
FILED Wednesday, January 30, 2019
APPL NO 16/261616
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/70 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11687581 Nandi et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Arnab Nandi (Columbus, Ohio);  Ritesh Sarkhel (Columbus, Ohio);  Codi Burley (Grove City, Ohio)
ABSTRACT An end-to-end software framework is provided for information extraction, enrichment, and caching in applications that involve exploring real-world data through a camera-based viewport in an augmented reality (AR) setting. It allows users to gather supplementary information through cross-modal data fusion against cloud-based datastores. Additional context is provided by retrieving data units from remote datastores that are relevant to the queried item. Given that such datastores often do not fit in main memory, a client-server architecture is used. Users interact with real-world objects via a camera-enabled client interface, and queries are executed using gesture-based interactions as supplementary information is retrieved from a back-end server (if necessary) and overlaid in the client's live camera-view.
FILED Monday, March 22, 2021
APPL NO 17/208201
ART UNIT 2167 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/54 (20190101)
G06F 16/535 (20190101)
G06F 16/538 (20190101) Original (OR) Class
G06F 16/9574 (20190101)

Image or Video Recognition or Understanding
G06V 20/20 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688539 Levy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Jeremy Levy (Pittsburgh, Pennsylvania);  Feng Bi (Pittsburgh, Pennsylvania);  Patrick R. Irvin (Allison Park, Pennsylvania)
ABSTRACT A structure includes an electronically controllable ferromagnetic oxide structure that includes at least three layers. The first layer comprises STO. The second layer has a thickness of at least about 3 unit cells, said thickness being in a direction substantially perpendicular to the interface between the first and second layers. The third layer is in contact with either the first layer or the second layer or both, and is capable of altering the charge carrier density at the interface between the first layer and the second layer. The interface between the first and second layers is capable of exhibiting electronically controlled ferromagnetism.
FILED Monday, November 22, 2021
APPL NO 17/533044
ART UNIT 1785 — Miscellaneous Articles, Stock Material
CURRENT CPC
Static Stores
G11C 11/155 (20130101)
G11C 11/161 (20130101)
G11C 11/1675 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/40 (20130101)
H01F 10/06 (20130101)
H01F 10/193 (20130101)
H01F 10/3213 (20130101)
H01F 13/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11689318 Yavas et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Recep Can Yavas (Pasadena, California);  Victoria Kostina (Pasadena, California);  Michelle Effros (Pasadena, California)
ABSTRACT Communication systems and methods in accordance with various embodiments of the invention employ a rateless coding strategy in which an encoder utilizes codewords located within a restricted subset of a multi-dimensional sphere. In one embodiment, a transmitter is configured to encode message data as symbols using a rateless code until an end of epoch message is received, where the rateless code comprises a set of codewords characterized in that they are located within a restricted subset of a multi-dimensional sphere. A receiver receives observed symbols and at each of a predetermined set of decode times, determines whether a decoding rule is satisfied. When the decoding rule is satisfied, the receiver decodes at least one message using the rateless code and transmits an end of epoch message.
FILED Monday, January 11, 2021
APPL NO 17/146462
ART UNIT 2631 — Digital Communications
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0643 (20130101)
H04L 1/0687 (20130101) Original (OR) Class
H04L 12/1868 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11689660 Adolphe et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Forward Edge AI, Inc. (San Antonio, Texas)
ASSIGNEE(S)
INVENTOR(S) Eric Adolphe (San Antonio, Texas);  Jesse Cai (McLean, Virginia);  Karthik Prasanna Maiya (Chantilly, Virginia);  Hongyi Guan (Herndon, Virginia);  Ben Sisko Adolphe (San Antonio, Texas)
ABSTRACT An innovative method is implemented to determine a robocall and blocks the incoming communication deemed to be a robocall. The method leverages blockchain's shared storage, memory, and ability to transact all information across a network and independently verified and stored on the immutable blockchain. The method takes advantage high-speed cellular network to process each communication with high-speed. Further, the method integrates blockchain encryption, swarm intelligence (SI), artificial intelligence (AI) and machine learning (ML) algorithms, a telecommunication expert knowledge graph (TEKG), and real-time parsing of records to block robocalls and reduce connection delays. All modules can evolve and update themselves with each use of the present invention through various SI, AI, and ML technologies. Additionally, the method includes a localized call-filtering feature based on state and federal laws to ensure the blocking of calls that are prohibited by either federal or state governments thereby facilitating recovery of damages.
FILED Thursday, December 03, 2020
APPL NO 17/110688
ART UNIT 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/06 (20130101)
H04L 9/50 (20220501)

Telephonic Communication
H04M 3/436 (20130101) Original (OR) Class
H04M 2203/6027 (20130101)

Wireless Communication Networks
H04W 12/12 (20130101)
H04W 12/72 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11684614 Abergel et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Rebecca J. Abergel (Kensington, California);  Taylor A. Choi (South San Francisco, California);  Kenneth N. Raymond (Berkeley, California);  David K. Shuh (Oakland, California)
ABSTRACT Provided herein are pharmaceutical formularions comprising a 1,2-HOPO chelating agent and/or 3,2-HOPO chelating agent.
FILED Tuesday, September 05, 2017
APPL NO 16/330601
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0056 (20130101)
A61K 9/0095 (20130101)
A61K 9/1611 (20130101)
A61K 9/1623 (20130101)
A61K 9/1652 (20130101)
A61K 9/2009 (20130101)
A61K 9/2018 (20130101)
A61K 9/2054 (20130101)
A61K 31/444 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 39/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684910 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Ailiance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Lucun Wang (Idaho Falls, Idaho);  Dong Ding (Idaho Falls, Idaho);  Yunya Zhang (Idaho Falls, Idaho);  Ting He (Idaho Falls, Idaho)
ABSTRACT A composite media for non-oxidative C2H6 dehydrogenation comprises an aluminosilicate zeolite matrix, and an EDH catalyst on one or more of an external surface of the aluminosilicate zeolite matrix and internal surfaces within pores of the aluminosilicate zeolite matrix. The EDH catalyst comprises one or more of Fe, Zn, Pt, Ga, alloys thereof, and oxides thereof. A C2H6 activation system, and a method of processing a C2H6-containing stream are also described.
FILED Monday, July 15, 2019
APPL NO 17/260486
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 8/009 (20130101)
B01J 8/0285 (20130101)
B01J 8/0292 (20130101)
B01J 29/44 (20130101)
B01J 29/46 (20130101) Original (OR) Class
B01J 29/405 (20130101)
B01J 35/023 (20130101)
B01J 35/026 (20130101)
B01J 35/1019 (20130101)
B01J 35/1038 (20130101)
B01J 2208/00017 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/26 (20130101)
C01B 2203/041 (20130101)
C01B 2203/0277 (20130101)

Acyclic or Carbocyclic Compounds
C07C 5/3335 (20130101)
C07C 5/3337 (20130101)
C07C 2529/44 (20130101)
C07C 2529/46 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684959 Whalen et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Scott A. Whalen (West Richland, Washington);  Vineet V. Joshi (Richland, Washington);  Md. Reza-E-Rabby (Richland, Washington);  Jens T. Darsell (West Richland, Washington);  Mageshwari Komarasamy (Richland, Washington);  Curt A. Lavender (Richland, Washington);  Glenn J. Grant (Benton City, Washington);  Aashish Rohatgi (Richland, Washington);  William E. Frazier, III (Richland, Washington)
ABSTRACT Devices and methods for performing shear-assisted extrusion processes for forming extrusions of a desired composition from a feedstock material are provided. The processes can use a device having a scroll face having an inner diameter portion bounded by an outer diameter portion, and a member extending from the inner diameter portion beyond a surface of the outer diameter portion. Extrusion feedstocks and extrusion processes are provided for forming extrusions of a desired composition from a feedstock. The processes can include providing a feedstock having at least two different materials and engaging the materials with one another within a feedstock container. Methods for preparing metal sheets are provided that can include preparing a metal tube via shear assisted processing and extrusion; opening the metal tube to form a sheet having a first thickness; and rolling the sheet to a second thickness that is less than the first thickness.
FILED Friday, February 04, 2022
APPL NO 17/665433
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material
B21C 23/002 (20130101) Original (OR) Class
B21C 23/04 (20130101)
B21C 23/218 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685050 Beer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) N. Reginald Beer (Pleasanton, California);  David H. Chambers (Livermore, California);  Jeffrey Edward Mast (Loveland, Colorado)
ABSTRACT A system for generating a machine learning system to generate guidance information based on locations of objects is provided. The system accesses training data that includes training time-of-arrival (“TOA”) information of looks and guidance information for each look. The guidance information is based on a training collection of object locations. The TOA of a look represents, for each object location of a training collection of object locations, times between signals transmitted by transmitters and return signals received by receivers. The return signals represent signals reflected from an object at the object location. The system trains a machine learning system using the training data wherein the machine learning system inputs TOA information and outputs guidance information.
FILED Wednesday, November 27, 2019
APPL NO 16/697652
ART UNIT 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1676 (20130101) Original (OR) Class

Aeroplanes; Helicopters
B64C 39/024 (20130101)

Unmanned aerial vehicles [UAV]; equipment therefor
B64U 10/13 (20230101)
B64U 2201/10 (20230101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 13/02 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0088 (20130101)
G05D 1/101 (20130101)

Image Data Processing or Generation, in General
G06T 7/70 (20170101)
G06T 2207/30252 (20130101)

Image or Video Recognition or Understanding
G06V 20/10 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685836 Percival et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Stephen John Percival (Albuquerque, New Mexico);  C. Garrett Campbell (Albuquerque, New Mexico);  Mathias C. Celina (Albuquerque, New Mexico);  Erik David Spoerke (Albuquerque, New Mexico);  Eric John Schindelholz (Columbus, Ohio)
ABSTRACT Nanocomposite anticorrosion coating can be achieved by depositing alternating, multilayers of a cross-linkable polymer and dispersed and aligned inorganic platelets followed by cross-linking of the cross-linkable polymer. The cross-linkable polymer can be an externally cross-linkable polymer that is cross-linked by diffusing a cross-linking agent into the deposited multilayer coating. Alternately, the cross-linkable polymer can be a functionalized cross-linkable polymer that is cross-linked by self-curing, thermal heat curing, or light (e.g., UV) following deposition of the multilayer coating.
FILED Wednesday, September 23, 2020
APPL NO 17/029630
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 7/148 (20130101)
B05D 7/542 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/346 (20130101)
C08K 7/00 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/084 (20130101) Original (OR) Class
C09D 7/70 (20180101)
C09D 139/02 (20130101)
C09D 163/00 (20130101)
C09D 179/02 (20130101)

Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25
C23F 11/173 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685897 Vandersarl et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
SLAC National Accelerator Laboratory (SLAC)
Federally Funded Research and Development Center (FFRDC)
Operated by Stanford University (LSJU) at Menlo Park, CA
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Jules J. Vandersarl (Eagle, Idaho);  Alexander M. Xu (Stanford, California);  Nicholas A. Melosh (Menlo Park, California);  Noureddine Tayebi (Stanford, California)
ABSTRACT In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of making a structure including nanotubes, a structure including nanotubes, methods of delivering a fluid to a cell, methods of removing a fluid to a cell, methods of accessing intracellular space, and the like.
FILED Monday, December 10, 2018
APPL NO 16/215503
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 40/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0075 (20130101) Original (OR) Class
C12N 2521/00 (20130101)
C12N 2533/10 (20130101)
C12N 2533/30 (20130101)
C12N 2535/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685942 Church et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Office of Science Consolidated Service Center (CSC)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) George M. Church (Brookline, Massachusetts);  Po-Yi Huang (Boston, Massachusetts)
ABSTRACT A method of making a polypeptide including one or more D-amino acids is provided. The method includes combining a ribosome with protein translation factors including (1) a template encoding the polypeptide, wherein the template encoding the polypeptide includes one or more codons which have been recoded to accept a tRNA attached to a D-amino acid, (2) a plurality of L-amino acids and a plurality of corresponding tRNAs, (3) a plurality of D-amino acids and their corresponding aminoacyl tRNA synthetase or a plurality of tRNAs ligated with a D-amino acid, and (4) elongation factor P in a concentration of 2 to 20 micromolar, wherein translation of the template encoding the polypeptide occurs to produce the polypeptide including one or more D-amino acids.
FILED Friday, March 03, 2017
APPL NO 16/081989
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686024 Ridley et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Other Lab, LLC (San Francisco, California)
ASSIGNEE(S) OTHER LAB, LLC (San Francisco, California)
INVENTOR(S) Brent Ridley (Huntington Beach, California);  Saul Griffith (San Francisco, California);  Shara Maikranz (San Francisco, California);  Jean Chang (San Francisco, California);  Pete Lynn (Oakland, California)
ABSTRACT An adaptive textile that includes a plurality of a first fiber having a first expansion coefficient and a plurality of a second fiber having a second expansion coefficient. There is a difference between the expansion coefficient of the first fiber and the expansion coefficient of the second fiber; at least one of the first or second fibers is a twisted coil actuator; and linear displacement of the twisted coil actuator causes the adaptive textile to bend.
FILED Tuesday, September 29, 2020
APPL NO 17/036210
ART UNIT 1789 — Miscellaneous Articles, Stock Material
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 31/065 (20190201)
A41D 2500/00 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/266 (20130101)
B32B 5/04 (20130101)
B32B 5/06 (20130101)
B32B 5/12 (20130101)
B32B 5/022 (20130101)
B32B 5/024 (20130101)
B32B 5/026 (20130101)
B32B 5/26 (20130101)
B32B 7/05 (20190101)
B32B 7/12 (20130101)
B32B 15/02 (20130101)
B32B 15/04 (20130101)
B32B 15/08 (20130101)
B32B 15/14 (20130101)
B32B 27/02 (20130101)
B32B 27/08 (20130101)
B32B 2250/02 (20130101)
B32B 2250/20 (20130101)
B32B 2250/24 (20130101)
B32B 2262/02 (20130101)
B32B 2307/30 (20130101)
B32B 2307/51 (20130101)
B32B 2307/54 (20130101)
B32B 2307/56 (20130101)
B32B 2307/58 (20130101)
B32B 2307/304 (20130101)
B32B 2307/416 (20130101)
B32B 2307/516 (20130101)
B32B 2307/518 (20130101)
B32B 2307/546 (20130101)
B32B 2307/554 (20130101)
B32B 2307/706 (20130101)
B32B 2307/724 (20130101)
B32B 2307/732 (20130101)
B32B 2307/7265 (20130101)
B32B 2437/00 (20130101)
B32B 2535/00 (20130101)
B32B 2601/00 (20130101)

Knitting
D04B 21/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686508 Baumann et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Theodore F. Baumann (Discovery Bay, California);  Joe H. Satcher, Jr. (Patterson, California);  Joseph C. Farmer (Tracy, California)
ABSTRACT An adsorptive cooling system includes two highly adsorptive structures positioned to receive thermal energy from a thermal energy source, each highly adsorptive structure includes a substrate and a metal-organic framework (MOF) coupled to the respective substrate and adapted for adsorbing and desorbing a refrigerant under predetermined thermodynamic conditions. The adsorptive cooling system includes a cooling unit and a circulation system adapted for circulating the refrigerant from one of the highly adsorptive structures to the cooling unit to provide cooling from the thermal energy source and to return the refrigerant from the cooling unit to the same or other highly adsorptive structure. Each substrate may include a plurality of microchannels, providing ingress and egress paths for a refrigerant, defined by grooves in a surface of the substrate nearest the MOF and/or surfaces of a plurality of microcapillaries of the substrate. The microchannels provide ingress and egress paths for a refrigerant.
FILED Monday, September 28, 2020
APPL NO 17/035206
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 17/08 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 29/49359 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686535 Borghese et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Honeywell International Inc. (Charlotte, North Carolina)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Joseph Borghese (Yucca Valley, California);  Quang Do (La Palma, California);  David Berukhim (Los Angeles, California);  Rafael Maldonado (Redondo Beach, California)
ABSTRACT A heat exchanger includes a shell housing a plurality of tubes and defining an exhaust fluid flow path within a first volume enclosed by the shell. The outer surfaces of the plurality of tubes are in fluid communication with the exhaust fluid flow path. The heat exchanger includes a cap attached to a first end of the shell and defining a second volume. A header is configured to separate the first volume from the second volume, flex with thermal expansion, and define tube inlet and outlet positions. The tube inlets and outlets are in fluid communication with a source fluid flow path, and each tube is substantially U-shaped and defines a flow path of the source fluid within the exhaust fluid flow path. The heat exchanger includes at least one longitudinal flow baffle within the shell configured to reduce an amount of exhaust fluid that may bypass the tubes.
FILED Monday, January 18, 2021
APPL NO 17/151534
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/10 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 7/06 (20130101)
F28D 7/0083 (20130101)
F28D 7/1607 (20130101)
F28D 21/001 (20130101) Original (OR) Class

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 9/0243 (20130101)
F28F 2225/08 (20130101)
F28F 2265/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686622 Rieker et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a body corporate (, None)
INVENTOR(S) Gregory B. Rieker (Boulder, Colorado);  Caroline B. Alden (Boulder, Colorado);  Robert J. Wright (Boulder, Colorado);  Sean C. Coburn (Longmont, Colorado)
ABSTRACT A frequency-measurement method uses a dual frequency-comb spectrometer as an optical wavemeter to measure the frequency of a reference laser that is used to frequency-stabilize the spectrometer. The method includes measuring a walking rate of center bursts in a sequence of interferograms recorded by the spectrometer, determining a number of teeth in each of a plurality of Nyquist windows formed by the dual frequency-comb spectrometer, and determining a Nyquist number of the one Nyquist window covering the laser frequency. The reference laser frequency can then be determined from the number of teeth in each Nyquist window, the Nyquist number, and the comb spacing of either one of the two frequency combs of the dual frequency-comb spectrometer. The reference laser frequency does not need to be measured with a separate wavemeter, or calibrated with respect to a known atomic or molecular transition.
FILED Wednesday, September 16, 2020
APPL NO 17/023080
ART UNIT 2877 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/4531 (20130101) Original (OR) Class
G01J 2003/2866 (20130101)
G01J 2003/4538 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/274 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11687369 Chen et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Tong Chen (Yorktown Heights, New York);  John Kevin O'Brien (South Salem, New York);  Daniel A. Prener (Croton-On-Hudson, New York);  Zehra N. Sura (Yorktown Heights, New York)
ABSTRACT Methods and systems for optimizing an application for a computing system having multiple distinct memory locations that are interconnected by one or more communication channels include determining one or more data handling properties for a data region in an application. One or more data handling policies for the data region are determined based on the one or more data handling properties. Data setup costs are determined for a scope in the application that uses the data region in different memory locations based on the one or more data handling properties. The application is optimized in accordance with the one or more data handling policies and the data setup costs for the different memory locations.
FILED Tuesday, March 02, 2021
APPL NO 17/189856
ART UNIT 2199 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/5016 (20130101) Original (OR) Class

Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use
Y02D 10/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11687460 LeBeane et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Sunnyvale, California)
INVENTOR(S) Michael W. LeBeane (Austin, Texas);  Walter B. Benton (Austin, Texas);  Vinay Agarwala (Sunnyvale, California)
ABSTRACT Methods, devices, and systems for GPU cache injection. A GPU compute node includes a network interface controller (NIC) which includes NIC receiver circuitry which can receive data for processing on the GPU, NIC transmitter circuitry which can send the data to a main memory of the GPU compute node and which can send coherence information to a coherence directory of the GPU compute node based on the data. The GPU compute node also includes a GPU which includes GPU receiver circuitry which can receive the coherence information; GPU processing circuitry which can determine, based on the coherence information, whether the data satisfies a heuristic; and GPU loading circuitry which can load the data into a cache of the GPU from the main memory if on the data satisfies the heuristic.
FILED Wednesday, April 26, 2017
APPL NO 15/498076
ART UNIT 2136 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0813 (20130101)
G06F 12/0828 (20130101) Original (OR) Class
G06F 12/0831 (20130101)
G06F 12/1081 (20130101)
G06F 13/28 (20130101)
G06F 2212/154 (20130101)
G06F 2212/621 (20130101)
G06F 2212/622 (20130101)
G06F 2212/1021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688550 Hatch et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kasas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Jonathan Douglas Hatch (Cleveland, Missouri);  Bob Dearth (Kansas City, Missouri);  Ida Sanchez (Leawood, Kansas);  Francisco Garcia-Moreno (Lee's Summit, Missouri)
ABSTRACT Systems and methods for forming a magnetically-enabled part via additive manufacturing. The method includes depositing a layer of additive manufacturing material on a build plate, melting or sintering the layer of additive manufacturing material, depositing additional layers of additive manufacturing material on previous layers of additive manufacturing material, the additive manufacturing material of at least some of the additional layers being magnetically permeable, and melting or sintering the additional layers of additive manufacturing material such that the magnetically-enabled part has a transition region including at least some of the magnetically permeable additive manufacturing material.
FILED Tuesday, October 20, 2020
APPL NO 17/075265
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/00 (20210101) Original (OR) Class
B22F 10/10 (20210101)

Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/342 (20151001)
B23K 2101/36 (20180801)
B23K 2103/04 (20180801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 40/20 (20200101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 41/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688596 Prieto Conaway et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Maria C. Prieto Conaway (Pleasanton, California);  Joshua R. Deotte (Livermore, California);  Nikola Dudukovic (Hayward, California);  Eric B. Duoss (Danville, California);  Bryan D. Moran (Pleasanton, California)
ABSTRACT The present disclosure relates to a lattice substrate adapted for use in direct ionization mass spectrometry. The substrate may have a plurality of tessellated unit cells forming an integral structure. Each tessellated unit cell may have a dimension of no more than about 1.5 mm and may include a plurality of pores arranged in an ordered pattern. The substrate may further include a form factor suitable for use with a direct ionization mass spectrometry system.
FILED Friday, February 12, 2021
APPL NO 17/175302
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0409 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688777 Haeberlen et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Infineon Technologies Austria AG (Villach, Austria)
ASSIGNEE(S) Infineon Technologies Austria AG (Villach, Austria)
INVENTOR(S) Oliver Haeberlen (St. Magdalen, Austria);  Eric G. Persson (Minnetonka, Minnesota);  Reenu Garg (Redondo Beach, California)
ABSTRACT In an embodiment, a semiconductor device is provided that includes a lateral transistor device having a source, a drain and a gate, and a monolithically integrated capacitor coupled between the gate and the drain.
FILED Monday, October 26, 2020
APPL NO 17/079615
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/642 (20130101)
H01L 29/41758 (20130101) Original (OR) Class
H01L 29/42316 (20130101)
H01L 29/66446 (20130101)

Pulse Technique
H03K 17/6871 (20130101)
H03K 2217/0081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11688892 Johnson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UChicago Argonne, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Christopher S. Johnson (Naperville, Illinois);  Anna Lee (Darien, Illinois)
ABSTRACT A process for charging a discharged electrochemical cell includes applying a voltage bias to the discharged electrochemical cell; and illuminating the cathode with a light source.
FILED Thursday, January 14, 2021
APPL NO 17/148875
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/502 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 10/44 (20130101) Original (OR) Class
H01M 10/052 (20130101)
H01M 10/441 (20130101)
H01M 10/0525 (20130101)
H01M 2004/028 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/00 (20130101)
H02J 7/35 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11689605 Grant et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Ryan Grant (Albuquerque, New Mexico);  William Whitney Schonbein (Albuquerque, New Mexico)
ABSTRACT A method and apparatus for performing operations by network interface cards in a network of computers. A network interface card is configured to receive a message and to interpret the message to identify a primitive operation to be performed. The primitive operation is one of a plurality of primitive operations that are performed to perform an operation. The primitive operation is performed by the network interface card and a trigger signal is generated in response to performing the primitive operation. The trigger signal is interpreted to identify a triggered message. The triggered message identifies a next one of the plurality of primitive operations to be performed. The triggered message is transmitted back to the network interface card or to another network interface card in the network for processing.
FILED Thursday, April 16, 2020
APPL NO 16/850994
ART UNIT 2455 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 9/5011 (20130101)
G06F 2209/509 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11689618 Cintuglu et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Hitachi Energy Switzerland AG (Baden, Switzerland)
ASSIGNEE(S) HITACHI ENERGY SWITZERLAND AG (Baden, Switzerland)
INVENTOR(S) Mehmet H. Cintuglu (Raleigh, North Carolina);  Dmitry Ishchenko (Raleigh, North Carolina)
ABSTRACT Systems, methods, techniques and apparatuses of asynchronous communication is distributed systems are disclosed. One exemplary embodiment is a method determining, with a plurality of agent nodes structured to communicate asynchronously in a distributed system, a first set of iterations including an iteration determined by each of the plurality of agent nodes; determining, with a first agent node of the plurality of agent nodes, a local vector clock; receiving, with the first agent node, a first iteration of the first set of iterations and a remote vector clock determined based on the first iteration; updating, with the first agent node, the local vector clock based on the received remote vector clock; and determining a first iteration of a second set of iterations based on the first set of iterations after determining all iterations of the first set of iterations have been received based on the local vector clock.
FILED Wednesday, December 18, 2019
APPL NO 16/718685
ART UNIT 2456 — Computer Networks
CURRENT CPC
Electric Digital Data Processing
G06F 17/16 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/1095 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11685129 Juarez et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINSTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Peter D. Juarez (Hampton, Virginia);  Elizabeth D. Gregory (Hampton, Virginia)
ABSTRACT Systems, methods, and devices are provided for the creation of predictable and accurate defects in a fiber tow of an Automated Fiber Placement (AFP) process, with such artificial defects being useful to support calibration of an in situ inspection system used in the AFP process. Various embodiments include methods for creating such artificial defects that support calibration of an in situ inspection system of an AFP system or process. Various embodiments may also include a defect stencils for an AFP system or process.
FILED Friday, December 04, 2020
APPL NO 17/112442
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/382 (20130101) Original (OR) Class
B29C 70/545 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/93 (20130101)
G01N 21/8851 (20130101)
G01N 2021/8472 (20130101)
G01N 2021/8874 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685516 Ivanco et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Thomas G. Ivanco (Yorktown, Virginia);  Patrick S. Heaney (Gloucester, Virginia);  Charles Chiou (Virgina Beach, Virginia)
ABSTRACT A passive gust load alleviation device for an aerodynamic panel includes a free-floating aerodynamic control surface connected to the panel via a revolute joint. A counterweight is connected to the control surface. Relative to a direction of ambient airflow, the counterweight has a center of gravity forward of the axis of rotation. The counterweight is configured to passively deflect the control surface about the axis to alleviate a gust load. A vehicle includes an aerodynamic panel connected to a body and extending into ambient airflow, and the control surface and counterweight. A method for alleviating the gust load on an aircraft panel includes connecting the control panel, via the revolute joint, along a trailing edge of the panel, and during a flight of an aircraft having the panel, passively deflecting the control panel about the axis in response to an incident wind gust.
FILED Friday, August 06, 2021
APPL NO 17/395747
ART UNIT 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 3/50 (20130101)
B64C 5/10 (20130101)
B64C 13/16 (20130101)
B64C 13/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685983 Sherman et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Terves, LLC (Euclid, Ohio)
ASSIGNEE(S) TERVES, LLC (Euclid, Ohio)
INVENTOR(S) Andrew J. Sherman (Mentor, Ohio);  Nicholas Farkas (Euclid, Ohio)
ABSTRACT A castable, moldable, or extrudable magnesium-based alloy that includes one or more insoluble additives. The insoluble additives can be used to enhance the mechanical properties of the structure, such as ductility and/or tensile strength. The final structure can be enhanced by heat treatment, as well as deformation processing such as extrusion, forging, or rolling, to further improve the strength of the final structure as compared to the non-enhanced structure. The magnesium-based composite has improved thermal and mechanical properties by the modification of grain boundary properties through the addition of insoluble nanoparticles to the magnesium alloys. The magnesium-based composite can have a thermal conductivity that is greater than 180 W/m-K, and/or ductility exceeding 15-20% elongation to failure.
FILED Monday, July 08, 2019
APPL NO 16/504621
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 19/14 (20130101)
B22D 21/04 (20130101)
B22D 21/007 (20130101)
B22D 23/06 (20130101)
B22D 25/06 (20130101)
B22D 27/00 (20130101)
B22D 27/02 (20130101)
B22D 27/08 (20130101)
B22D 27/11 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/054 (20220101)
B22F 1/054 (20220101)
B22F 1/062 (20220101)
B22F 1/0547 (20220101)
B22F 1/0547 (20220101)
B22F 1/0551 (20220101)
B22F 1/0551 (20220101)
B22F 2202/01 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 10/00 (20130101)

Alloys
C22C 1/03 (20130101)
C22C 1/0408 (20130101)
C22C 1/0408 (20130101)
C22C 1/1047 (20230101)
C22C 1/1047 (20230101)
C22C 1/1047 (20230101)
C22C 1/1047 (20230101)
C22C 1/1047 (20230101)
C22C 1/1047 (20230101)
C22C 1/1047 (20230101)
C22C 23/00 (20130101)
C22C 23/02 (20130101)
C22C 23/06 (20130101)
C22C 26/00 (20130101)
C22C 47/08 (20130101)
C22C 47/08 (20130101)
C22C 49/02 (20130101)
C22C 49/04 (20130101)
C22C 2026/002 (20130101)
C22C 2026/002 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/06 (20130101) Original (OR) Class

Foundations; Excavations; Embankments; Underground or Underwater Structures
E02D 27/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11686584 Arumugam
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Darmindra D. Arumugam (Pasadena, California)
ABSTRACT Methods and systems for indoor position sensing are disclosed. The described methods and systems are based on magnetoquasistatic field coupling theory and can be implemented in two- and three-dimensional, long-range, through-the-wall applications, where the transmitting devices are implemented outdoor, the receiving device is implemented indoor, or vice versa. Measurement systems implemented to characterize the disclosed methods are also presented for both two- and three-dimensional applications involving indoor position sensing. Orientation sensing methods and systems are also disclosed.
FILED Thursday, August 06, 2020
APPL NO 16/987205
ART UNIT 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/206 (20130101) Original (OR) Class
G01C 21/3635 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0274 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11689942 Barsoum et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Constellation Designs, LLC (Anaheim, California)
ASSIGNEE(S) Constellation Designs, LLC (Anaheim, California)
INVENTOR(S) Maged F. Barsoum (San Jose, California);  Christopher R. Jones (Pacific Palisades, California)
ABSTRACT Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation.
FILED Thursday, May 26, 2022
APPL NO 17/804306
ART UNIT 2632 — Digital Communications
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 13/255 (20130101)
H03M 13/6325 (20130101)

Transmission
H04B 15/00 (20130101)
H04B 17/336 (20150115)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0003 (20130101)
H04L 1/0009 (20130101)
H04L 27/3405 (20130101)
H04L 27/3483 (20130101)
H04L 27/3809 (20130101)

Wireless Communication Networks
H04W 24/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11684045 Drennan et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) HiveTech Solutions Inc. (Wilmington, Delaware)
ASSIGNEE(S) HiveTech Solutions Inc. (Wilmington, Delaware)
INVENTOR(S) Kimberly A Drennan (Boulder, Colorado);  Justin T Bellucci (Boulder, Colorado);  Chelsea Cook (Phoenix, Arizona);  Diana Glawe (Yellow Springs, Ohio)
ABSTRACT A mobile indoor controlled apiary system includes a mobile foundation, a plurality of insulated panels configured for modular assembly to form a structural envelope on top of the mobile foundation, and a removable shell configured for covering the structural envelope. The system further includes a data collection system for gathering environmental data within the structural envelope, and a climate control system configured for regulating environmental conditions within the structural envelope.
FILED Friday, April 10, 2020
APPL NO 16/846208
ART UNIT 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 1/0047 (20130101)
A01K 29/005 (20130101)
A01K 47/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11684667 Baker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
APPLICANT(S) LOYOLA UNIVERSITY CHICAGO (Maywood, Illinois)
ASSIGNEE(S) LOYOLA UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S) Susan Baker (Elmhurst, Illinois);  Xufang Deng (Lyons, Illinois)
ABSTRACT Coronaviruses, vaccines comprising the same, and methods for preventing disease. One embodiment of such includes a live, attenuated coronavirus comprising a variant replicase gene encoding polyproteins comprising a non-structural protein (nsp)-15, the replicase gene encoding the nsp15 and causes any change, including mutations and/or deletions, that affects the stability or activity of the nsp15.
FILED Friday, March 02, 2018
APPL NO 15/910617
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/215 (20130101) Original (OR) Class
A61K 2039/5254 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)
C12N 2770/20022 (20130101)
C12N 2770/20034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11685927 Ulmasov et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) COVERCRESS INC. (St. Louis, Missouri);  BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (Normal, Illinois);  REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) COVERCRESS INC. (St. Louis, Missouri);  BOARD OF TRUSTEES OF ILLINOIS STATE UNIVERSITY (Normal, Illinois);  REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Tim Ulmasov (Chesterfield, Missouri);  John C. Sedbrook (Bloomington, Illinois);  Michael David Marks (Roseville, Minnesota);  Ratan Chopra (St. Paul, Minnesota)
ABSTRACT Pennycress (Thlaspi arvense) seed, seed lots, seed meal, and compositions with reduced glucosinolate content as well as plants that yield such seed, seed lots, seed meal, and compositions are provided. Methods of making and using the pennycress plants and/or seed that provide such seed, seed lots, seed meal, and compositions are also provided.
FILED Tuesday, March 02, 2021
APPL NO 17/249431
ART UNIT 1663 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 5/10 (20130101)
A01H 6/20 (20180501)

Fodder
A23K 10/30 (20160501)
A23K 40/10 (20160501)
A23K 50/10 (20160501)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8245 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 11689277 Zeng et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
Data Communications Program (DATACOMM)
APPLICANT(S) The MITRE Corporation (McLean, Virginia)
ASSIGNEE(S) THE MITRE CORPORATION (McLean, Virginia)
INVENTOR(S) Dongsong Zeng (Germantown, Maryland);  John C. Gonda, III (Falls Church, Virginia)
ABSTRACT Disclosed herein are system, method, and computer program product embodiments for utilizing parallel links to improve sub-network availability and latency performance for ATC traffic. An embodiment operates by receiving a generated message. The type of the generated message is determined, where the type is an air traffic control message or a non-air traffic control message. Based on the type of message, communication links are selected, where the communication links include parallel transmission links or a serial link. The method continues by copying the generated message and transmitting the copied message using the selected communication links. The method waits to receive an acknowledgement indicating receipt of the transmitted message. Upon identifying an acknowledgement, any of the copied messages not yet retransmitted are deleted.
FILED Monday, April 05, 2021
APPL NO 17/222450
ART UNIT 2415 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 7/18506 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 45/245 (20130101)
H04L 47/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11685885 Mohapatra et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Subhra Mohapatra (Lutz, Florida);  Shyam S. Mohapatra (Lutz, Florida);  Tao Wang (Tampa, Florida)
ABSTRACT A 4D-perfused tumoroid-on-a-chip platform used in personalized cancer treatment. The platform includes a plate with a plurality of bottomless wells that resides atop a microfluidic channel layer, which in turn resides atop a surface acoustic wave (SAW) based sensor layer that is capable of measuring potential pH values of fluids disposed within the platform. The microfluidic channel layer includes a plurality of bioreactors, with each bioreactor including an inlet well, a culture well, and an outlet well. The inlet well, culture well, and outlet well form a closed system via fluid conduits spanning from the inlet well to the culture well, as well as from the culture well to the outlet well. Due to the fluid flow from the plate to the chip, and from the inlet well to the outlet well on the chip through the culture well, target cell (tumoroid) growth is promoted within the culture well.
FILED Monday, February 24, 2020
APPL NO 16/799413
ART UNIT 1799 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2300/0627 (20130101)
B01L 2300/0819 (20130101)
B01L 2300/0829 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/12 (20130101)
C12M 23/16 (20130101) Original (OR) Class
C12M 25/14 (20130101)
C12M 41/26 (20130101)
C12M 41/36 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0693 (20130101)
C12N 2503/02 (20130101)
C12N 2513/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 11688048 Breish et al.
FUNDED BY
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) DIGITAL CHECK CORP. (Northbrook, Illinois)
ASSIGNEE(S) DIGITAL CHECK CORP. (Northbrook, Illinois)
INVENTOR(S) Kurt Breish (Garden Valley, Idaho);  Torin Ford (Boise, Idaho)
ABSTRACT Methods and systems for blending line image data streams from a film scanner are disclosed. In one embodiment, a method is provided including receiving multiple data streams from line scan sensors. An overlap position may then be initially selected, which forms an overlap position between two of the data streams. A difference measure may then be calculated between the two data streams within the overlap area. The overlap positions may then be iteratively altered between a plurality of overlap positions, and additional difference measures may be computed for each overlap position. A blending position may then be selected from the plurality of overlap positions, which may correspond to the overlap position with the smallest difference measure. The data streams may then be blended at the selected blending position.
FILED Friday, January 31, 2020
APPL NO 16/778874
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/50 (20130101) Original (OR) Class
G06T 7/0002 (20130101)
G06T 7/97 (20170101)
G06T 2207/10008 (20130101)
G06T 2207/20221 (20130101)
G06T 2207/20224 (20130101)

Pictorial Communication, e.g Television
H04N 1/00665 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11686725 Shi et al.
FUNDED BY
Non-Profit Organization (NPO)
California Institute for Regenerative Medicine (CIRM)
APPLICANT(S) CITY OF HOPE (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Yanhong Shi (Arcadia, California);  Li Li (Glendale, California)
ABSTRACT Disclosed are methods of detecting abnormal expression of one or more genes associated with a neurological disease such as the Alexander disease, the Alzheimer's disease, the Parkinson disease, the Huntington disease, multiple sclerosis, and amyotrophic lateral sclerosis. The methods include performing a transcriptome analysis of the astrocytes derived from a patient and the astrocytes derived from a healthy control subject, thereby to determine one or more genes that are substantially differentially expressed. Also disclosed are methods of treating a neurological disease by correcting the abnormally expressed genes associated with the neurological disease.
FILED Monday, July 08, 2019
APPL NO 16/505534
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101)

Peptides
C07K 16/28 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0622 (20130101)
C12N 5/0696 (20130101)
C12N 2310/20 (20170501)
C12N 2310/141 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5058 (20130101) Original (OR) Class
G01N 2570/00 (20130101)
G01N 2800/285 (20130101)
G01N 2800/2821 (20130101)
G01N 2800/2835 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11689660 Adolphe et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Forward Edge AI, Inc. (San Antonio, Texas)
ASSIGNEE(S)
INVENTOR(S) Eric Adolphe (San Antonio, Texas);  Jesse Cai (McLean, Virginia);  Karthik Prasanna Maiya (Chantilly, Virginia);  Hongyi Guan (Herndon, Virginia);  Ben Sisko Adolphe (San Antonio, Texas)
ABSTRACT An innovative method is implemented to determine a robocall and blocks the incoming communication deemed to be a robocall. The method leverages blockchain's shared storage, memory, and ability to transact all information across a network and independently verified and stored on the immutable blockchain. The method takes advantage high-speed cellular network to process each communication with high-speed. Further, the method integrates blockchain encryption, swarm intelligence (SI), artificial intelligence (AI) and machine learning (ML) algorithms, a telecommunication expert knowledge graph (TEKG), and real-time parsing of records to block robocalls and reduce connection delays. All modules can evolve and update themselves with each use of the present invention through various SI, AI, and ML technologies. Additionally, the method includes a localized call-filtering feature based on state and federal laws to ensure the blocking of calls that are prohibited by either federal or state governments thereby facilitating recovery of damages.
FILED Thursday, December 03, 2020
APPL NO 17/110688
ART UNIT 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/06 (20130101)
H04L 9/50 (20220501)

Telephonic Communication
H04M 3/436 (20130101) Original (OR) Class
H04M 2203/6027 (20130101)

Wireless Communication Networks
H04W 12/12 (20130101)
H04W 12/72 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US D990479 Edmonds, III et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Dean S. Edmonds, III (Great Falls, Virginia);  David S. Dao (Annandale, Virginia);  William Carter, II (Front Royal, Virginia);  Daniel J. Widdershoven (Alexandria, Virginia);  David William Cerutti (Alexandria, Virginia)
ABSTRACT
FILED Tuesday, June 15, 2021
APPL NO 29/794856
ART UNIT 2914 — Design
CURRENT CPC
Recording, communication, or information retrieval equipment
D14/447
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11686577 Warren et al.
FUNDED BY
APPLICANT(S) United Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Eli C. Warren (Wethersfield, Connecticut);  Kevin A. Ford (Killingworth, Connecticut);  Patrick M. Harrington (West Hartford, Connecticut)
ABSTRACT An angled face cap probe includes a housing having a radially inner end and a radially outer end, defining a cavity, and configured to be located radially outward from an airfoil. The angled face cap probe further includes a sensor located in the cavity at the radially inner end of the housing, having a sensor body with a sensing face that is angled to match or substantially match an angle of a radially outward face the airfoil, and having a sensor flat that is elongated in a first direction. The angled face cap probe further includes an outer cap located in the cavity, coupled to the housing, and having an outer cap main body and cap legs that extend radially inward from the outer cap main body to interface with the sensor flat to resist rotation of the sensor relative to the housing.
FILED Thursday, September 20, 2018
APPL NO 16/137189
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 21/003 (20130101)
F01D 21/04 (20130101)

Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 21/16 (20130101) Original (OR) Class

Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 11/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 27, 2023.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230627.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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