FedInvent™ Patents
Patent Details for Tuesday, July 18, 2023
This page was updated on Monday, July 24, 2023 at 04:26 PM GMT
Department of Health and Human Services (HHS)
| US 11701054 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio); Adaptive Sensory Technology, Inc. (San Diego, California) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio); ADAPTIVE SENSORY TECHNOLOGY, INC. (San Diego, California) |
| INVENTOR(S) | Zhong-Lin Lu (Dublin, Ohio); Yukai Zhao (Columbus, Ohio); Luis A. Lesmes (San Diego, California) |
| ABSTRACT | The present disclosure relates to systems and methods for characterizing a behavior change of a process. A behavior model that can include a set of behavior parameters can be generated based on behavior data characterizing a prior behavior change of a process. A stimulus parameter for a performance test can be determined based on the set of behavior parameters. An application of the performance test to the process can be controlled based on the stimulus parameter to provide a measure of behavior change of the process. Response data characterizing one or more responses associated with the process during the performance test can be received. The set of behavior parameters can be updated based on the response data to update the behavior model characterizing the behavior change of the process. In some examples, the behavior model can be evaluated to improve or affect a future behavior performance of the process. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 16/492525 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/16 (20130101) A61B 5/4005 (20130101) Original (OR) Class A61B 5/4082 (20130101) A61B 5/4088 (20130101) A61B 5/4842 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) G06N 20/00 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701061 | Desai et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland (College Park, Maryland) |
| INVENTOR(S) | Jaydev P. Desai (Marietta, Georgia); Hardik Jeetendra Pandya (Bangalore, India); Kihan Park (Atlanta, Georgia) |
| ABSTRACT | A MEM-based device and method of fabrication, the device comprising a biochip substrate comprising one or more compliant materials, a plurality of mechanical and electrical micro-sensors configured in an array to simultaneously measure electrical and mechanical properties of a sample, wherein a first mechanical micro-sensor is formed as a patterned layer of at least one of the compliant materials, wherein the patterned layer is coupled to a first pillar comprising a dielectric material formed onto the compliant materials, the first pillar being coated with a metal film at a contact surface with the sample and along a side of the first pillar to act as a conductive probe for the first electrical micro-sensor, and wherein the first pillar is formed on the first mechanical micro-sensor to transfer a force to the first mechanical micro-sensor. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/011642 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0062 (20130101) A61B 5/68 (20130101) A61B 5/72 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/59 (20130101) G01N 21/6458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701073 | Harrison et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Daniel David Harrison (Delanson, New York); Ge Wang (Loudonville, New York) |
| ABSTRACT | Systems and method for performing X-ray computed tomography (CT) that can improve spectral separation and decrease motion artifacts without increasing radiation dose are provided. The systems and method can be used with either a kVp-switching source or a single-kVp source. When used with a kVp-switching source, an absorption grating and a filter grating can be disposed between the X-ray source and the sample to be imaged. Relative motion of the filter and absorption gratings can by synchronized to the kVp switching frequency of the X-ray source. When used with a single-kVp source, a combination of absorption and filter gratings can be used and can be driven in an oscillation movement that is optimized for a single-kVp X-ray source. With a single-kVp source, the absorption grating can also be omitted and the filter grating can remain stationary. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 17/354286 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/482 (20130101) A61B 6/4007 (20130101) A61B 6/4035 (20130101) Original (OR) Class A61B 6/4085 (20130101) A61B 6/5258 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701134 | Maxwell et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Adam D. Maxwell (Ann Arbor, Michigan); Zhen Xu (Ann Arbor, Michigan); Hitinder S. Gurm (Ann Arbor, Michigan); Charles A. Cain (Ann Arbor, Michigan) |
| ABSTRACT | Methods for performing non-invasive thrombolysis with ultrasound using, in some embodiments, one or more ultrasound transducers to focus or place a high intensity ultrasound beam onto a blood clot (thrombus) or other vascular inclusion or occlusion (e.g., clot in the dialysis graft, deep vein thrombosis, superficial vein thrombosis, arterial embolus, bypass graft thrombosis or embolization, pulmonary embolus) which would be ablated (eroded, mechanically fractionated, liquefied, or dissolved) by ultrasound energy. The process can employ one or more mechanisms, such as of cavitational, sonochemical, mechanical fractionation, or thermal processes depending on the acoustic parameters selected. This general process, including the examples of application set forth herein, is henceforth referred to as “Thrombolysis.” |
| FILED | Friday, June 10, 2022 |
| APPL NO | 17/838085 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0536 (20130101) A61B 8/00 (20130101) A61B 8/08 (20130101) A61B 8/485 (20130101) A61B 17/2258 (20130101) A61B 17/22004 (20130101) Original (OR) Class A61B 2017/00154 (20130101) A61B 2017/00172 (20130101) A61B 2017/00778 (20130101) A61B 2017/22001 (20130101) A61B 2017/22008 (20130101) A61B 2017/22088 (20130101) A61B 2017/22089 (20130101) A61B 2090/378 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701144 | McDonnall et al. |
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| FUNDED BY |
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| APPLICANT(S) | Veritas IP, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | Veritas IP, LLC (Salt Lake City, Utah) |
| INVENTOR(S) | Daniel Allen McDonnall (Salt Lake City, Utah); Nathaniel Anthony Srok (Salt Lake City, Utah); Christopher Farand Smith (North Salt Lake, Utah) |
| ABSTRACT | Disclosed herein are systems and methods for insertion tools for implanting electrode leads. In one embodiment, an insertion tool comprises a shaft having an outer cannula and an inner cannula. An actuator may be configured to transition the insertion tool between at least three configurations. In a first configuration, the inner cannula and the outer cannula are configured to receive the lead in the shaft. In a second configuration, the inner cannula and the outer cannula are configured to secure the lead in the shaft. In a third configuration, the inner cannula and the outer cannula are configured to cause the lead to separate from the insertion tool and implant in adjacent tissue. |
| FILED | Thursday, February 03, 2022 |
| APPL NO | 17/591843 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3421 (20130101) A61B 17/3468 (20130101) Original (OR) Class A61B 2017/00367 (20130101) A61B 2017/00438 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701227 | Kheradvar et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Arash Kheradvar (Irvine, California); Gregory Scott Kelley (Santee, California) |
| ABSTRACT | A gimbal handle assembly including: an inner gimbal and an outer gimbal that are concentrically linked and have pivot axes that are orthogonal relative to each other, a spool coupled to and rotatable around the outer gimbal, and a plurality of draw lines attached to the spool in a circumferential configuration, wherein rotation of the spool and/or rotation of the spool and the outer and inner gimbals increases or reduces tension in the draw lines. Also disclosed are a transcatheter valve delivery assembly that includes the gimbal handle assembly, a multi-lumen catheter, a sleeve attached to a distal end of the multi-lumen catheter, and a transcatheter heart valve including an expandable valve frame. Methods of delivering the transcatheter valve to a subject are described, wherein pitch and yaw orientations of the transcatheter valve can be precisely controlled with enhanced degrees of freedom. |
| FILED | Tuesday, May 05, 2020 |
| APPL NO | 16/866913 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/95 (20130101) A61F 2/2418 (20130101) A61F 2/2436 (20130101) A61F 2/2439 (20130101) Original (OR) Class A61F 2/9517 (20200501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701232 | Guo et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Ting Guo (Cambridge, Massachusetts); John Patrick Fisher (Kensington, Maryland); Hannah Baker (Baltimore, Maryland); Max Jonah Lerman (Silver Spring, Maryland); Robert Choe (Arlington, Virginia) |
| ABSTRACT | An implantable acellular polymeric scaffold device functionalized with aggrecan is provided. Also provided are methods of fabricating a polymeric scaffold device, including methods of fabricating the scaffold device via 3D printing. Methods of treating a cartilage defect in a subject in need thereof comprise application of the disclosed scaffold device in combination with microfracture procedures. A specialized lid for a centrifugation well plate is also provided. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743315 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/30756 (20130101) Original (OR) Class A61F 2002/30766 (20130101) A61F 2002/30985 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701328 | Balu-Iyer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Buffalo, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| INVENTOR(S) | Sathy Balu-Iyer (Amherst, New York); Richard Bankert (Eden, New York); Radha Ramakrishnan (Plainsboro, New Jersey); Robert Dingman (Henrietta, New York); Vandana Iyer (Amherst, New York); Jennifer Schneider (Boston, Massachusetts); Fiona Yau Glassman (Central Islip, New York); Nhan Hanh Nguyen (Amherst, New York) |
| ABSTRACT | Compositions and methods for inducing immune tolerance to proteins and subsequence administration of the proteins are disclosed. Compositions comprise proteins complexed with liposomes comprising PS and PC, wherein at least part of the PS is present as lyso-PS. |
| FILED | Thursday, March 19, 2020 |
| APPL NO | 16/823912 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 31/203 (20130101) A61K 31/436 (20130101) A61K 38/38 (20130101) A61K 38/39 (20130101) A61K 38/47 (20130101) A61K 38/168 (20130101) A61K 38/1709 (20130101) Enzymes C12Y 302/0102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701334 | Dewji |
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| FUNDED BY |
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| APPLICANT(S) | Cura Therapeutics, LLC (La Jolla, California) |
| ASSIGNEE(S) | Cura Therapeutics, LLC (La Jolla, California) |
| INVENTOR(S) | Nazneen Dewji (San Diego, California) |
| ABSTRACT | Provided herein are pharmaceutical compositions, each comprising a phenylsulfonamide, for example, a compound of Formula I, or an enantiomer, a mixture of enantiomers, a mixture of two or more diastereomers, a tautomer, a mixture of two or more tautomers, or an isotopic variant thereof; or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof; and a pharmaceutically acceptable excipient. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a neurodegenerative disease. |
| FILED | Tuesday, January 08, 2019 |
| APPL NO | 16/961191 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/18 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701345 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Hongbing Wang (Ellicot City, Maryland); Fengtian Xue (Potomac, Maryland); Dongdong Liang (Baltimore, Maryland) |
| ABSTRACT | The invention relates to selective small molecule human constitutive androstane receptor (hCAR) activators of Formula (I) or (II), pharmaceutical compositions thereof, and use thereof for the treatment of hematologic malignancies and other cancers. The small molecule hCAR activator in combination with CPA based chemotherapy regimen provides a synergistic effect to help promote cytoxicity of the cyclophosphamide (CPA) based anticancer treatments including CHOP regimen (CPA, doxorubicin, vincristine, and prednisone) by preferential induction of CYP2B6 over CYP3A4 and promoting the formation of therapeutically active CPA metabolite 4-OH-CPA. |
| FILED | Tuesday, June 19, 2018 |
| APPL NO | 16/623453 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/424 (20130101) A61K 31/429 (20130101) Original (OR) Class A61K 31/475 (20130101) A61K 31/519 (20130101) A61K 31/573 (20130101) A61K 31/704 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) C07D 498/04 (20130101) C07D 513/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701346 | Spellberg et al. |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Brad Spellberg (Los Angeles, California); Brian Luna (Los Angeles, California) |
| ABSTRACT | To identify novel agents to treat carbapenem-resistant Acinetobacter baumannii. the Inventors used a nutrient-depleted medium with serum to mimic the in vivo environment. In RPMI with serum, the screen identified rifabutin (RBT) as being 133-fold more potent than rifampin (RIF) against A. baumannii, with MICs of 0.031 μg/ml and 4 μg/ml respectively. No difference in RBT vs. RIF activity was observed when MHII was used as the culture media. RBT possesses markedly superior in efficacy to RIF in murine models of lethal iv and pneumonia models of infection with a hyper-virulent, clinical lung and blood isolate of extreme-drug resistant (XDR) A. baumannii. In both models, RBT significantly improved survival and lowered bacterial burden compared to RIF. RBT is a promising, novel therapeutic option for A. baumannii infections. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821861 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/438 (20130101) Original (OR) Class A61K 31/438 (20130101) A61K 38/12 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701361 | Cambier et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| ASSIGNEE(S) | NATIONAL INSTITUTES OF HEALTH (NCH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT NIH DIVISION OF EXTRAMURAL INVENTIONS AND TECHNOLOGY RESOURCES (DEITR) (Bethesda, Maryland); THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| INVENTOR(S) | John Cambier (Denver, Colorado); Elizabeth Franks (Denver, Colorado) |
| ABSTRACT | Methods of using a phosphoinositide 3-kinase p110-delta inhibitor to treat, delay the onset, or slow the progression of an autoimmune disease or disorder in a subject, without suppressing the subject's B cell responses to exogenous antigens or rendering the subject immunocompromised, as well as pharmaceutical compositions containing phosphoinositide 3-kinase p110-delta inhibitors in amounts suitable for convenient and accurate administration within these therapeutic methods. |
| FILED | Monday, January 07, 2019 |
| APPL NO | 16/959960 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 37/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701364 | Lairson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Luke L. Lairson (San Diego, California); Emily Chin (San Diego, California); Arnab K. Chatterjee (San Diego, California); Manoj Kumar (San Diego, California); Ana Maria Gamo Albero (La Jolla, California); Hank Michael James Petrassi (San Diego, California); Peter G. Schultz (La Jolla, California); Chenguang Yu (La Jolla, California); Junko Tamiya (Carlsbad, California); William Vernier (Vista, California); Anil Gupta (San Diego, California); Ramkumar Modukuri (Houston, Texas) |
| ABSTRACT | The invention provides compounds having STimulator of INterferon Genes (STING) agonistic bioactivity that can be used in the treatment of tumors in patients afflicted therewith. The compounds are of formula (I): as defined herein. Compounds for practice of a method of the invention can be delivered via oral delivery for systemic exposure, as well as delivered intratumorally. Antitumor therapy using a compound of formula (I) can further comprise administration of an effective dose of an immune-checkpoint targeting drug. |
| FILED | Thursday, February 21, 2019 |
| APPL NO | 15/733535 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/127 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 31/536 (20130101) A61K 31/5365 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/6803 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701371 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Lingyin Li (Stanford, California); Mark Smith (San Francisco, California); Kelsey Erin Shaw (Atlanta, Georgia); Jacqueline Ann Carozza (Stanford, California); Volker Boehnert (Palo Alto, California) |
| ABSTRACT | Compounds, compositions and methods are provided for the inhibition of ENPP1. Aspects of the subject methods include contacting a sample with a ENPP1 inhibitor to inhibit cGAMP hydrolysis activity of ENPP1. In some cases, the ENPP1 inhibitor is cell impermeable. Also provided are compositions and methods for treating cancer. Aspects of the methods include administering to a subject a therapeutically effective amount of a ENPP1 inhibitor to treat the subject for cancer. In certain cases, the cancer is a solid tumor cancer. Also provided are methods of administering radiation therapy to a subject either before or after administering an ENPP1 inhibitor. The radiation therapy can be administered at a dosage and/or frequency effective to reduce radiation damage to the subject. In certain cases, the method is performed in combination with a chemotherapeutic agent, or a checkpoint inhibitor, or both. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/645300 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701379 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island) |
| ASSIGNEE(S) | Rhode Island Hospital (Providence, Rhode Island) |
| INVENTOR(S) | Qian Chen (Barrington, Rhode Island); Yupeng Chen (Sharon, Massachusetts); Hongchuan Yu (Chestnut Hill, Massachusetts) |
| ABSTRACT | The compositions and methods of the invention provide compositions and methods for preferential targeting of tissues to delivery therapeutic or diagnostic agents. For example, such compounds are useful in the treatment of joint disorders those affecting articulating joints, e.g., injury-induced osteoarthritis as well as autoimmune diseases affecting joint tissue such as rheumatoid arthritis. |
| FILED | Tuesday, March 26, 2019 |
| APPL NO | 17/041399 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Original (OR) Class A61K 47/545 (20170801) A61K 47/6929 (20170801) A61K 47/6949 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) C12N 2310/141 (20130101) C12N 2320/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701380 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Jian Liu (Chapel Hill, North Carolina); Zhangjie Wang (Changchun, China PRC); Po-Hung Hsieh (Pasadena, California); Yongmei Xu (Durham, North Carolina) |
| ABSTRACT | Heparin compounds and synthetic heparin analogues having short acting anticoagulant activity are provided. Methods of synthesizing such heparin compounds, including chemoenzymatic pathways using sulfotransferase enzymes are provided. Methods of treating subjects in need of anticoagulant activity are provided. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 16/492858 |
| ART UNIT | 1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/727 (20130101) Original (OR) Class A61K 38/4846 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) Polysaccharides; Derivatives Thereof C08B 37/0075 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) C12P 19/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701389 | Galipeau et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Jacques Galipeau (Madison, Wisconsin); Raghavan Chinnadurai (Tucker, Georgia) |
| ABSTRACT | This disclosure relates to methods of preserving mesenchymal stromal/stem cells (MSCs) for use in clinical applications. In certain embodiments, this disclosure relates to methods of preserving MSCs comprising mixing MSCs with interferon-gamma prior to cryopreserving, freezing, or cooling the MSCs to a temperature below zero degrees Celsius. |
| FILED | Thursday, March 09, 2017 |
| APPL NO | 16/083661 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0215 (20130101) A01N 1/0221 (20130101) A01N 1/0226 (20130101) A01N 1/0284 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) C12N 2501/24 (20130101) C12N 2523/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701433 | Lei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Yu Lei (Ann Arbor, Michigan); Yee Sun Tan (Ann Arbor, Michigan); Kanokwan Sansanaphongpricha (Ann Arbor, Michigan); Duxin Sun (Ann Arbor, Michigan); Hongwei Chen (Ann Arbor, Michigan); Hongxiang Hu (Ann Arbor, Michigan) |
| ABSTRACT | The present invention provides methods, compositions, systems, and kits comprising nano-satellite complexes and/or serum albumin carrier complexes, which are used for modulating antigen-specific immune response (e.g., enhancing anti-tumor immunity). In certain embodiments, the nano-satellite complexes comprise: a) a core nanoparticle complex comprising a biocompatible coating surrounding a nanoparticle core; b) at least one satellite particle attached to, or absorbed to, the biocompatible coating; and c) an antigenic component conjugated to, or absorbed to, the at least one satellite particle component. In certain embodiments, the complexes further comprise: d) an type I interferon agonist agent. In some embodiments, the serum albumin complexes comprise: a) at least part of a serum albumin protein, b) an antigenic component conjugated to the carrier protein, and c) a type I interferon agonist agent. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 16/619802 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/02 (20130101) A61K 39/0003 (20130101) A61K 39/0011 (20130101) A61K 39/118 (20130101) A61K 39/385 (20130101) A61K 47/643 (20170801) A61K 47/646 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Original (OR) Class A61K 2039/60 (20130101) A61K 2039/572 (20130101) A61K 2039/622 (20130101) A61K 2039/55561 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701436 | Roy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Subhojit Roy (Madison, Wisconsin); Jichao Sun (Madison, Wisconsin) |
| ABSTRACT | Described herein is a method for treating Alzheimer's disease (AD) by selective silencing of the amyloid precursor protein (APP) using Cas9 nuclease gene editing. Methods of making and using genetic constructs comprising a Cas9 nuclease and a sequence encoding guide RNA (gRNA) specific to APP capable of truncating the C-terminus of APP, as well as compositions comprising these constructs, are provided. |
| FILED | Tuesday, October 05, 2021 |
| APPL NO | 17/494457 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 48/0008 (20130101) A61K 48/0058 (20130101) A61K 48/0066 (20130101) Original (OR) Class A61K 48/0075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 14/4711 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2740/16043 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701437 | Milanova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Denitsa M. Milanova (Boston, Massachusetts); George M. Church (Brookline, Massachusetts); Noah Davidsohn (Brookline, Massachusetts); Carl Schoellhammer (Medford, Massachusetts); Robert S. Langer (Newton, Massachusetts); Anna I. Mandinova (Newton, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts) |
| ABSTRACT | A method for the systemic delivery of a polypeptide within a subject is provided by creating genetically modified skin cells via topical introduction of a genetically engineered virus which delivers a nucleic acid encoding a therapeutic polypeptide for expression by the skin cells, wherein the expressed therapeutic polypeptide is secreted by the skin cells and is introduced into the circulatory system of the subject. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 16/612648 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/7023 (20130101) A61K 47/6901 (20170801) A61K 48/0075 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) C12N 2750/14151 (20130101) C12N 2810/859 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701450 | Leisk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| INVENTOR(S) | Gary G. Leisk (Somerville, Massachusetts); Tim Jia-Ching Lo (Taoyuan, Taiwan); Lei Li (Beijing, China PRC); Evangelia Bellas (Philadelphia, Pennsylvania); David L. Kaplan (Concord, Massachusetts) |
| ABSTRACT | The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein can be injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection). In some embodiments, the composition described herein comprises a compressed silk fibroin matrix, which can expand upon injection into the tissue and retain its original expanded volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void, e.g., for tissue repair and/or augmentation, or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments, the compositions described herein can be used for soft tissue repair or augmentation. |
| FILED | Thursday, September 22, 2016 |
| APPL NO | 15/273327 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1767 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/48 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3604 (20130101) A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2400/08 (20130101) A61L 2430/34 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701453 | Bertassoni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Luiz Bertassoni (Portland, Oregon); Anthony Tahayeri (Sherwood, Oregon); Avathamsa Athirasala (Hillsboro, Oregon); Jack L. Ferracane (Portland, Oregon) |
| ABSTRACT | Disclosed is a method for filling a root canal in a tooth. The method includes positioning a fiber in the root canal of the tooth, filling at least a portion of the root canal with an unset hydrogel composition, such that the unset hydrogel composition contacts at least a portion of the fiber, setting the hydrogel composition, thereby forming a set hydrogel, and removing the fiber from the set hydrogel, thereby leaving a channel in the set hydrogel. Methods and kits for repairing teeth are also described. |
| FILED | Wednesday, May 30, 2018 |
| APPL NO | 16/618329 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/12 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/222 (20130101) A61L 2400/06 (20130101) A61L 2430/12 (20130101) Compositions of Macromolecular Compounds C08L 89/06 (20130101) C08L 93/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701455 | Grunlan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Melissa A. Grunlan (College Station, Texas); Gerard L. Cote (College Station, Texas); Alexander A. Abraham (College Station, Texas); Ruochong Fei (College Station, Texas); Andrea K. Locke (College Station, Texas) |
| ABSTRACT | The disclosure provides a method for cleaning an implanted medical device. In one embodiment, the method includes providing a medical device including a membrane; wherein the membrane comprises a thermoresponsive hydrogel including N-isopropylacrylamide (NIPAAm) or poly(N-isopropylacrylamide) (PNIPAAm), and a volume phase transition temperature (VPTT). The method also includes implanting the medical device into a target area; wherein the membrane temperature is maintained at substantially the same temperature as the target area; wherein temperature fluctuations within the target area that approach, meet and/or exceed the volume phase transition temperature induce deswelling or relative deswelling in the membrane and temperature fluctuations within the target area that are relatively lower and/or approach and/or fall below the volume phase transition temperature induce swelling or relative swelling in the membrane. |
| FILED | Wednesday, January 27, 2016 |
| APPL NO | 15/545811 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1473 (20130101) A61B 5/14532 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/10 (20130101) A61L 31/048 (20130101) Original (OR) Class A61L 31/145 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/56 (20130101) Compositions of Macromolecular Compounds C08L 33/26 (20130101) C08L 2203/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702394 | Gouw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Arvin Gouw (San Francisco, California); Dean W. Felsher (San Mateo, California); Feng Jin (Stanford, California); Richard N. Zare (Stanford, California); Katherine Margulis (San Francisco, California); Steven R. Schow (Redwood City, California); Robert J. Greenhouse (Newark, California); David Loughhead (Belmont, California); Steven Richards (Stanford, California) |
| ABSTRACT | Inhibitors of Glycerol 3-Phosphate Acyltransferase (GPAT) are provided; and methods of use in the treatment of cancer; and treatment of conditions relating to metabolic syndrome and hyperlipidemia. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/968836 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 311/08 (20130101) Heterocyclic Compounds C07D 295/092 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702402 | Qi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Jun Qi (Sharon, Massachusetts); Kenneth C. Anderson (Wellesley, Massachusetts); Lei Wu (Shanghai, China PRC); Yan Song (Brookline, Massachusetts); Dharminder Chauhan (Natick, Massachusetts) |
| ABSTRACT | Provided herein are bifunctional compounds with a moiety (e.g., lenalidomide, thalidomide) that is a binder of an E3 ubiquitin ligase (e.g., Cereblon) and another moiety (e.g., RA190) that is a binder of the ubiquitin receptor RPN13 to induce degradation of RPN13 and thereby inhibit proteasome function. Also provided are pharmaceutical compositions comprising the bifunctional compounds, and methods of treating and/or preventing diseases (e.g., proliferative diseases, cancers, benign neoplasms, pathological angiogenesis, inflammatory diseases, and autoimmune diseases). Provided also are methods of inducing the degradation of ubiquitin receptor RPN13 by administering a bifunctional compound or composition described herein, wherein one component of the bifunctional compound is a binder of an E3 ubiquitin ligase (e.g., lenalidomide, thalidomide) and another component of the compound is a binder of ubiquitin receptor RPN13 (e.g., RA190) in a subject. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/969458 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class C07D 495/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702403 | Hodgetts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio); THE BRIGHAM AND WOMAN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Kevin Hodgetts (Boston, Massachusetts); Chien-Liang Glenn Lin (Columbus, Ohio) |
| ABSTRACT | Disclosed are compounds that activate excitatory amino acid transporter 2 (EAAT2), as well as methods of using these compounds to treat or preventing diseases, disorders, and conditions associated with glutamate excitotoxicity. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 16/972311 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/22 (20180101) A61P 25/24 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 237/14 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 413/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702417 | Slaugenhaupt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); The United States Of America, as represented by the secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Susan A. Slaugenhaupt (Hingham, Massachusetts); Graham Johnson (Sanbornton, New Hampshire); William D. Paquette (Amsterdam, New York); Wei Zhang (Sharon, Massachusetts); Juan Marugan (Gaithersburg, Maryland) |
| ABSTRACT | Provided herein are compounds useful for improving mRNA splicing in a cell. Exemplary compounds provided herein are useful for improving mRNA splicing in genes comprising at least one exon ending in the nucleotide sequence CAA. Methods for preparing the compounds and methods of treating diseases of the central nervous system are also provided. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/877254 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 405/12 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) C07D 473/16 (20130101) C07D 473/34 (20130101) Original (OR) Class C07D 487/04 (20130101) C07D 495/04 (20130101) C07D 513/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702442 | Tor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yitzhak Tor (San Diego, California); Yao Li (San Diego, California); Andrea Fin (San Diego, California) |
| ABSTRACT | The disclosure provides cyclic dinucleotides that are useful as STING agonists, pharmaceutical compositions and vaccines comprising the cyclic dinucleotides, and methods of treating diseases and disorders using the cyclic dinucleotides, pharmaceutical compositions, and vaccines. |
| FILED | Thursday, August 27, 2020 |
| APPL NO | 17/005045 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Original (OR) Class C07H 21/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702453 | Tai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Andrew Tai (Ann Arbor, Michigan); David Lin (Ann Arbor, Michigan) |
| ABSTRACT | The disclosure provides materials in the form of flavivirus variants that each encode a Non-Structural Protein-1 (NS1) variant, wherein the coding region is a chimera of at least two different NS1 coding regions, or wherein the coding region has at least one mutation in a codon of a canonical Asn-Xxx-Ser/Thr N-linked glycosylation site, wherein Asn is asparagine, Xxx is any amino acid, and Ser/Thr is either serine or threonine, or wherein the coding region is both a chimera and has at least one mutation in a codon of a canonical N-liked glycosylation site, wherein Asn is asparagine, Xxx is any amino acid, and Ser/Thr is either serine or threonine. The disclosure also provides methods of using such flavivirus variants to inhibit the transmission of infectious flavivirus. |
| FILED | Tuesday, August 20, 2019 |
| APPL NO | 17/269191 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7052 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 14/1825 (20130101) Original (OR) Class C07K 2319/91 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/24122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702464 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Patrick Wilson (Chicago, Illinois); Yaoqing Chen (Chicago, Illinois); Haley L. Dugan (Chicago, Illinois) |
| ABSTRACT | Provided herein are anti-neuraminidase agents useful for neutralization of influenza virus infection, and methods of use and manufacture thereof. In particular, compositions comprising anti-neuraminidase agents (e.g., antibodies) that are cross-reactive with multiple influenza strains are provided, as well as methods of treatment and prevention of influenza infection therewith. |
| FILED | Friday, March 01, 2019 |
| APPL NO | 16/977327 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702472 | Adusumilli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); The U.S.A. as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); THE U.S.A. AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Prasad S. Adusumilli (New York, New York); Michel Sadelain (New York, New York); Dimiter S. Dimitrov (Frederick, Maryland); Yang Feng (Frederick, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) that specifically target human mesothelin, and immunoresponsive cells comprising such CARs. The presently disclosed mesothelin-targeted CARs have enhanced immune-activating properties, including anti-tumor activity. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821674 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/705 (20130101) C07K 14/4748 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 2317/21 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702480 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bin Liu (San Francisco, California); Namkyung Lee (San Francisco, California); Yang Su (San Francisco, California); Scott Bidlingmaier (San Francisco, California) |
| ABSTRACT | The present disclosure relates to an engineered antibody that co-engages a cell type-selective (or specific) antigen (guide) and a signaling receptor (effector) on a target cell. In some instances, the engineered antibody is capable of modulating a signaling pathway on a target cell. In other embodiments, an engineered antibody of the present disclosure is administered to a subject for the treatment of a disease or condition. |
| FILED | Friday, November 17, 2017 |
| APPL NO | 16/349958 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Peptides C07K 16/30 (20130101) Original (OR) Class C07K 16/468 (20130101) C07K 16/2821 (20130101) C07K 16/2866 (20130101) C07K 2317/31 (20130101) C07K 2317/64 (20130101) C07K 2317/76 (20130101) C07K 2317/77 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702545 | Choi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Hak Soo Choi (Needham, Massachusetts); Jonghan Kim (Cambridge, Massachusetts); Georges El Fakhri (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are compounds that are able to bind metal ions (e.g., free metal ions or metal ions bound to low affinity ligands) in a sample or subject. Also provided herein are methods of using the compounds for chelating metal ions and for the treatment of diseases associated with abnormal levels of metal ions. Methods of preparing the compounds and pharmaceutical compositions are also provided. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 17/733766 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 23/0025 (20130101) C09B 23/0033 (20130101) C09B 23/0041 (20130101) C09B 23/0066 (20130101) Original (OR) Class C09B 69/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702637 | Woods et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ossium Health, Inc. (San Francisco, California) |
| ASSIGNEE(S) | Ossium Health, Inc. (San Francisco, California) |
| INVENTOR(S) | Erik John Woods (Carmel, Indiana); Brian H. Johnstone (Fishers, Indiana); Dongsheng Gu (Indianapolis, Indiana); Aubrey Marie Sherry (Carmel, Indiana); Kelsey Gwen Musall (Avon, Indiana); John R. Woods (Indianapolis, Indiana); James Hardin (Columbia, South Carolina); Alan Hooks (Commerce City, Colorado) |
| ABSTRACT | Methods are provided for extracting bone marrow cells from bone obtained from deceased donors, for preparing the bone marrow for cryopreservation and for obtaining desired cells from cryopreserved and fresh bone marrow. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/013395 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Diagnosis; Surgery; Identification A61B 17/1611 (20130101) A61B 2017/00831 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702649 | Blainey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Paul Blainey (Cambridge, Massachusetts); Navpreet Ranu (Cambridge, Massachusetts); Todd Gierahn (Cambridge, Massachusetts); J. Christopher Love (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to the analysis of complex single cell sequencing libraries. Disclosed are methods for enrichment of library members based on the presence of cell-of origin barcodes to identify and concentrate DNA that is relevant to interesting cells or components that would be expensive or difficult to study otherwise. Also, disclosed are methods of capturing cDNA library molecules by use of CRISPR systems, hybridization or PCR. The present invention allows for identifying the properties of rare cells in single cell RNA-seq data and accurately profile them through clustering approaches. Further information on transcript abundances from subpopulations of single cells can be analyzed at a lower sequencing effort. The methods also allow for linking TCR alpha and beta chains at the single cell level. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/758640 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) C12N 15/1006 (20130101) Original (OR) Class C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/465 (20210501) Enzymes C12Y 301/11 (20130101) C12Y 302/02027 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) C40B 40/06 (20130101) C40B 40/10 (20130101) C40B 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702656 | Fu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xiang-Dong Fu (Rancho Santa Fe, California); Hao Qian (San Diego, California) |
| ABSTRACT | Provided herein is a method of reprogramming a non-neuronal cell to a neuron. Aspects of the present disclosure relate to using cell reprogramming agent suppresses the expression or activity of PTB to convert a non-neuronal cell into a neuron. Also provided herein is a method of treating neurodegenerative disease by reprogramming non-neuronal cells in vivo to functional neurons. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 16/986798 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702657 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aiming Yu (Sacramento, California); Joseph L Jilek (Davis, California); Qianyu Zhang (Davis, California); Pui Yan Ho (Davis, California); Meijuan Tu (Davis, California) |
| ABSTRACT | Provided are hybrid tRNA/pre-microRNA and tRNA molecules and their use in methods of preventing and treating hepatocellular carcinoma (HCC). In some embodiments, provided are polynucleotides that include a tRNA operably linked to one or more pre-microRNA (pre-miRNA), where the tRNA and/or pre-miRNA are operably linked to one or more inserted RNA molecules that inhibit the growth or proliferation of a hepatocellular carcinoma (HCC) cell. |
| FILED | Friday, April 19, 2019 |
| APPL NO | 17/048466 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/141 (20130101) C12N 2310/3519 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702659 | Khvorova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Vignesh Narayan Hariharan (Natick, Massachusetts); Sarah Davis (Wellesley, Massachusetts); Annabelle Biscans (Cambridge, Massachusetts); Ananth Karumanchi (Chestnut Hill, Massachusetts) |
| ABSTRACT | This disclosure relates to novel targets for angiogenic disorders. Novel oligonucleotides are also provided. Methods of using the novel oligonucleotides for the treatment of angiogenic disorders (e.g., preeclampsia) are also provided. |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 17/846526 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/344 (20130101) C12N 2310/346 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702672 | Yan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa); University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Ziying Yan (Iowa City, Iowa); John F. Engelhardt (Iowa City, Iowa); Jianming Qiu (Overland Park, Kansas) |
| ABSTRACT | A method of preparing a chimeric virus comprising bocavirus capsid protein (VP) and a recombinant adeno-associated (AAV) viral genome, and isolated mutant bocavirus genomes, are provided. |
| FILED | Wednesday, February 08, 2017 |
| APPL NO | 16/076219 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/015 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14143 (20130101) C12N 2800/22 (20130101) C12N 2810/6027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702673 | Zolotukhin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Sergei Zolotukhin (Gainesville, Florida); Oleksandr Kondratov (Gainesville, Florida) |
| ABSTRACT | Provided herein are methods and compositions useful in the production of recombinant AAV (rAAV) in host producer cells, such as insect cells. In some embodiments, methods, uses and compositions are provided that comprise recombinant VP1 genes comprising modified Kozak sequences to express AAV VP1 proteins in amounts that are useful for producing infective rAAV particles. These infective rAAV particles may comprise a gene of interest. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/657959 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/075 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0601 (20130101) C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2710/14041 (20130101) C12N 2710/14143 (20130101) C12N 2710/14144 (20130101) C12N 2750/14123 (20130101) C12N 2750/14143 (20130101) C12N 2750/14151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702675 | Ertl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE WISTAR INSTITUTE (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Wistar Institute (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Hildegund C. J. Ertl (Villanova, Pennsylvania); Xiang Yang Zhou (North Wales, Pennsylvania) |
| ABSTRACT | This disclosure provides replication-incompetent adenoviral vectors useful in vaccine development and gene therapy. The disclosed vectors comprise a selective deletion of E3 and are particularly useful for preparation of vaccines development and for gene therapy using toxic transgene products that result in vector instability that occurs when the entire E3 domain is deleted. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/037966 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 39/015 (20130101) A61K 39/21 (20130101) A61K 39/29 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/861 (20130101) C12N 2710/10043 (20130101) C12N 2710/10343 (20130101) C12N 2710/10352 (20130101) C12N 2740/16134 (20130101) C12N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702676 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Chengwen Li (Chapel Hill, North Carolina); Richard Jude Samulski (Hillsborough, North Carolina) |
| ABSTRACT | The present invention provides a polyploid adeno-associated virus (AAV) capsid, wherein the capsid comprises capsid protein VP1, wherein said capsid protein VP1 is from one or more than one first AAV serotype, wherein said capsid protein VP2 is from one or more than one first AAV serotype and capsid protein VP3, wherein said capsid protein VP3 is from one or more than one second AAV serotype and wherein at least one of said first AAV serotype is different from at least one of said second AAV serotype and is different from at least one of said third AAV serotype, in any combination. |
| FILED | Wednesday, November 18, 2020 |
| APPL NO | 16/951004 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0025 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) Peptides C07K 14/005 (20130101) C07K 2317/24 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/8645 (20130101) Original (OR) Class C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) C12N 2750/14151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702687 | Fan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Rong Fan (Cheshire, Connecticut); Yao Lu (New Haven, Connecticut); Nayi Wang (New Haven, Connecticut) |
| ABSTRACT | This disclosure demonstrates an approach that translates synthetic DNA codes to spatial codes registered in nanoliter microchambers for multiplexed measurement of nearly any type of molecular targets (e.g., miRNAs, mRNAs, intracellular and surface proteins) in single cells. |
| FILED | Monday, July 17, 2017 |
| APPL NO | 16/319188 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6837 (20130101) Original (OR) Class C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 2523/319 (20130101) C12Q 2523/319 (20130101) C12Q 2523/319 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/203 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2537/143 (20130101) C12Q 2565/514 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703510 | Bhatia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Sangeeta N. Bhatia (Lexington, Massachusetts); Geoffrey A. von Maltzahn (Boston, Massachusetts); Gabriel A. Kwong (Atlanta, Georgia) |
| ABSTRACT | The present invention relates to methods and products associated with in vivo enzyme profiling. In particular, the invention relates to methods of in vivo processing of exogenous molecules followed by detection of signature molecules as representative of the presence of active enzymes associated with diseases or conditions. The invention also relates to products, kits, and databases for use in the methods of the invention. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/091075 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 7/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) C12Q 1/56 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) G01N 33/6848 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704582 | Jain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VigNet Incorporated (Fairfax, Virginia) |
| ASSIGNEE(S) | VigNet Incorporated (Fairfax, Virginia) |
| INVENTOR(S) | Praduman Jain (Fairfax, Virginia); Dave Klein (Oakton, Virginia); Josh Schilling (Salem, Oregon) |
| ABSTRACT | Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for using machine learning to generate precision predictions of readiness. In some implementations, a database is accessed to obtain status data that indicates activities or attributes of a subject. A set of feature scores is derived from the status data for the subject, the set of feature scores including values indicative of attributes or activities of the subject. The set of feature scores to one or more models that have been configured to predict readiness of subjects to satisfy one or more readiness criteria. The one or models can be models configured using machine learning training. Based on processing performed using the one or more machine learning models and the set of feature scores, a prediction regarding the subject's ability to achieve readiness to satisfy the one or more readiness criteria is generated. |
| FILED | Wednesday, October 06, 2021 |
| APPL NO | 17/494879 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 24/00 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Original (OR) Class G06N 20/00 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704790 | Leuthardt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eric Leuthardt (St. Louis, Missouri); Carl Hacker (St. Louis, Missouri); Shan Siddiqi (St. Louis, Missouri); Tim Laumann (St. Louis, Missouri); Andy Daniel (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Eric Leuthardt (St. Louis, Missouri); Carl Hacker (St. Louis, Missouri); Shan Siddiqi (St. Louis, Missouri); Tim Laumann (St. Louis, Missouri); Andy Daniel (St. Louis, Missouri) |
| ABSTRACT | A target location for a therapeutic intervention is determined in a subject with a neurological disorder. The target location is selected within at least one resting state network (RSN) map according to a predetermined criterion for the neurological disorder. The at least one RSN map includes a plurality of functional voxels within a brain of the subject, and each functional voxel of the plurality of functional voxels is associated with a probability of membership in an RSN. Instructions are transmitted to a treatment system that cause operation to be performed on the selected target location. |
| FILED | Tuesday, September 25, 2018 |
| APPL NO | 16/141605 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 5/4848 (20130101) A61B 5/7267 (20130101) A61B 34/10 (20160201) A61B 2034/107 (20160201) A61B 2576/026 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Electric Digital Data Processing G06F 18/213 (20230101) G06F 18/2178 (20230101) G06F 18/2415 (20230101) G06F 18/24133 (20230101) Computer Systems Based on Specific Computational Models G06N 3/00 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30016 (20130101) Image or Video Recognition or Understanding G06V 10/764 (20220101) G06V 2201/031 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704809 | Buckland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Translational Imaging Innovations, Inc. (Hickory, North Carolina) |
| ASSIGNEE(S) | Translational Imaging Innovations, Inc. (Hickory, North Carolina) |
| INVENTOR(S) | Eric L. Buckland (Hickory, North Carolina); Micaela R. Mendlow (Jersey City, New Jersey); Robert C. Williams (Durham, North Carolina) |
| ABSTRACT | A method for segmenting images is provided including tessellating an image obtained from one of an image database and an imaging system into a plurality of sectors; classifying each of the plurality of sectors by applying one or more pre-defined labels to each of the plurality of sectors, wherein the pre-defined labels indicate at least one of an image quality metric (IQM) and a metric of structure; assigning each of the plurality of classified sectors an Image Quality Classification (IQC); identifying anchor sectors among the plurality of classified sectors, applying filtering and edge detection to identify target boundaries; applying contouring across contiguous sectors and using the assigned IQC as a guide to complete segmentation of an edge between any two identified anchor sectors; and smoothing across segmented regions to increase parametric second-order continuity. |
| FILED | Wednesday, January 06, 2021 |
| APPL NO | 17/142560 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/243 (20230101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/12 (20170101) Original (OR) Class G06T 2207/10101 (20130101) G06T 2207/20021 (20130101) G06T 2207/30041 (20130101) G06T 2207/30168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11706177 | Hsu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Patrick D. Hsu (San Francisco, California); Silvana Konermann (Menlo Park, California) |
| ABSTRACT | Provided herein are CRISPR/Cas methods and compositions for targeting RNA molecules, which can be used to detect, edit, or modify a target RNA. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 17/711924 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/85 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) C12N 15/8201 (20130101) C12N 15/8213 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) C12N 2310/3519 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/08 (20130101) H04L 9/30 (20130101) H04L 45/745 (20130101) H04L 51/08 (20130101) H04L 51/18 (20130101) H04L 51/212 (20220501) Original (OR) Class H04L 51/214 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11701144 | McDonnall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Veritas IP, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | Veritas IP, LLC (Salt Lake City, Utah) |
| INVENTOR(S) | Daniel Allen McDonnall (Salt Lake City, Utah); Nathaniel Anthony Srok (Salt Lake City, Utah); Christopher Farand Smith (North Salt Lake, Utah) |
| ABSTRACT | Disclosed herein are systems and methods for insertion tools for implanting electrode leads. In one embodiment, an insertion tool comprises a shaft having an outer cannula and an inner cannula. An actuator may be configured to transition the insertion tool between at least three configurations. In a first configuration, the inner cannula and the outer cannula are configured to receive the lead in the shaft. In a second configuration, the inner cannula and the outer cannula are configured to secure the lead in the shaft. In a third configuration, the inner cannula and the outer cannula are configured to cause the lead to separate from the insertion tool and implant in adjacent tissue. |
| FILED | Thursday, February 03, 2022 |
| APPL NO | 17/591843 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3421 (20130101) A61B 17/3468 (20130101) Original (OR) Class A61B 2017/00367 (20130101) A61B 2017/00438 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701245 | Shepherd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Robert F. Shepherd (Ithaca, New York); James Pikul (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure provides an electrohydraulic device. The device includes a battery having a vessel containing a flowable electrolyte. The battery may be a flow cell battery, such as, for example, a redox flow cell battery. In a flow cell battery, the flowable electrolyte may a catholyte and/or an anolyte. An actuator is in fluidic communication with the vessel of the battery. The actuator is configured to be actuated using the flowable electrolyte. A cation exchange membrane may separate the vessel into an anolyte side and a catholyte side. The actuator may be in fluidic communication with either side (anolyte side or catholyte side) of the vessel. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 17/605996 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/74 (20210801) Original (OR) Class A61F 2/586 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0288 (20130101) A61H 3/00 (20130101) A61H 2201/1238 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) H01M 8/04186 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701371 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Lingyin Li (Stanford, California); Mark Smith (San Francisco, California); Kelsey Erin Shaw (Atlanta, Georgia); Jacqueline Ann Carozza (Stanford, California); Volker Boehnert (Palo Alto, California) |
| ABSTRACT | Compounds, compositions and methods are provided for the inhibition of ENPP1. Aspects of the subject methods include contacting a sample with a ENPP1 inhibitor to inhibit cGAMP hydrolysis activity of ENPP1. In some cases, the ENPP1 inhibitor is cell impermeable. Also provided are compositions and methods for treating cancer. Aspects of the methods include administering to a subject a therapeutically effective amount of a ENPP1 inhibitor to treat the subject for cancer. In certain cases, the cancer is a solid tumor cancer. Also provided are methods of administering radiation therapy to a subject either before or after administering an ENPP1 inhibitor. The radiation therapy can be administered at a dosage and/or frequency effective to reduce radiation damage to the subject. In certain cases, the method is performed in combination with a chemotherapeutic agent, or a checkpoint inhibitor, or both. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/645300 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701450 | Leisk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| INVENTOR(S) | Gary G. Leisk (Somerville, Massachusetts); Tim Jia-Ching Lo (Taoyuan, Taiwan); Lei Li (Beijing, China PRC); Evangelia Bellas (Philadelphia, Pennsylvania); David L. Kaplan (Concord, Massachusetts) |
| ABSTRACT | The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein can be injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection). In some embodiments, the composition described herein comprises a compressed silk fibroin matrix, which can expand upon injection into the tissue and retain its original expanded volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void, e.g., for tissue repair and/or augmentation, or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments, the compositions described herein can be used for soft tissue repair or augmentation. |
| FILED | Thursday, September 22, 2016 |
| APPL NO | 15/273327 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1767 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/48 (20130101) A61L 27/50 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/227 (20130101) Original (OR) Class A61L 27/3604 (20130101) A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2400/08 (20130101) A61L 2430/34 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701784 | Pringle, IV et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | John Walter Pringle, IV (Torrance, California); Angelica Davancens (Reseda, California); Derek Adam Nelson (Long Beach, California) |
| ABSTRACT | A robot end effector for dispensing an extrudable substance comprises a chassis, cartridge bays, attached to the chassis and each shaped to receive a corresponding one of two-part cartridges, and a manifold, comprising a manifold outlet, manifold inlets, and a valve inlet. When the two-part cartridges are received by the cartridge bays, the manifold inlets are in fluidic communication with corresponding ones of the two-part cartridges via static mixers, attached to cartridge outlets of the two-part cartridges. The robot end effector additionally comprises a head assembly, comprising pairs of fittings, configured to selectively supply compressed air from a pressure source to the two-part cartridges when the two-part cartridges are received by the cartridge bays, so that contents of the two-part cartridges are concurrently extruded through the cartridge outlets. |
| FILED | Friday, May 22, 2020 |
| APPL NO | 16/882425 |
| ART UNIT | 3754 — Fluid Handling and Dispensing |
| CURRENT CPC | Apparatus for Applying Fluent Materials to Surfaces, in General B05C 5/0225 (20130101) B05C 11/1036 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 15/0019 (20130101) Original (OR) Class B25J 15/045 (20130101) B25J 19/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702202 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Michael L. Anderson (Colorado Springs, Colorado); Zachary Froembling (Yelm, Washington); Kaz I. Teope (Corvallis, Oregon) |
| ABSTRACT | A system, method and apparatus for unfolding and folding a multi-arm device that includes a support member and an actuator. A first arm is coupled to the actuator and extends from a folded position to an unfolded position upon actuation of the actuator. A second arm is coupled to the actuator and moves from a folded position to an unfolded position upon actuation of a linkage that causes the second arm to rotate. A third arm moves from a folded position to an unfolded position, via an elbow joint, upon release of a tether attached to the third arm. |
| FILED | Friday, May 03, 2019 |
| APPL NO | 16/402562 |
| ART UNIT | 3632 — Static Structures, Supports and Furniture |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/30 (20130101) B64C 27/33 (20130101) B64C 39/024 (20130101) Original (OR) Class Unmanned aerial vehicles [UAV]; equipment therefor B64U 10/13 (20230101) B64U 30/20 (20230101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/14 (20130101) Gearing F16H 25/2204 (20130101) Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 13/022 (20130101) F16M 2200/06 (20130101) F16M 2200/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702390 | Iacono et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Scott T. Iacono (Colorado Springs, Colorado); Chadron M. Friesen (Langley, Canada) |
| ABSTRACT | The present invention relates to a mechanochemical based synthesis of perfluoropyridine monomers, polymers made using such monomers and methods of making and using articles comprising such polymers. Such perfluoropyridine monomers are easily chemically tuned have the strength needed for high temperature applications and the flexibility needed for low temperature applications. In addition, to the aforementioned monomers, a mechanochemical based synthesis for such perfluoropyridine monomers is provided. All of the aforementioned performance application advantages are also found in polymers comprising Applicants' perfluoropyridine monomers. |
| FILED | Monday, December 05, 2022 |
| APPL NO | 18/075018 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Heterocyclic Compounds C07D 213/61 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0627 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 71/00 (20130101) Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 147/04 (20130101) C10M 169/041 (20130101) C10M 2203/003 (20130101) C10M 2213/06 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2050/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702472 | Adusumilli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); The U.S.A. as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); THE U.S.A. AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Prasad S. Adusumilli (New York, New York); Michel Sadelain (New York, New York); Dimiter S. Dimitrov (Frederick, Maryland); Yang Feng (Frederick, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides for methods and compositions for enhancing the immune response toward cancers and pathogens. It relates to chimeric antigen receptors (CARs) that specifically target human mesothelin, and immunoresponsive cells comprising such CARs. The presently disclosed mesothelin-targeted CARs have enhanced immune-activating properties, including anti-tumor activity. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821674 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/705 (20130101) C07K 14/4748 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 16/30 (20130101) C07K 2317/21 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702604 | Patel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nikhil Manubhai Patel (Grand Forks, North Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nikhil Manubhai Patel (Grand Forks, North Dakota) |
| ABSTRACT | gasifier and a gasification process provides a long, uniform temperature zone in the gasifier, regardless of the particle size, chemical composition, and moisture content of the fuel by sandwiching a reduction zones between two oxidation zones. The gasifier and gasification process produces a char that is more energy-dense and almost devoid of moisture, affording an additional (char) oxidation zone with a temperature that is higher than a first oxidation zone which is closer to an evaporation and devolatilization zone. As such, the additional (char) oxidation zone contributes to augmenting the reduction zone temperature, providing a favorable dual impact in improving syngas composition and near-complete conversion of the tar. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 17/570448 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/08 (20130101) Original (OR) Class C10J 3/22 (20130101) C10J 3/26 (20130101) C10J 3/723 (20130101) C10J 2300/092 (20130101) C10J 2300/093 (20130101) C10J 2300/0946 (20130101) C10J 2300/0956 (20130101) C10J 2300/0959 (20130101) C10J 2300/0976 (20130101) C10J 2300/1246 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 1/024 (20130101) C10K 1/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702622 | Raphael et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Marc P. Raphael (Springfield, Virginia); Wonmo Kang (Springfield, Virginia) |
| ABSTRACT | A system and method for studying cell injury mechanisms by applying biologically relevant mechanical impact to in vitro cell culture are disclosed. This approach is for maintaining consistent in vitro conditions during experiments, accommodating multiple cell populations, and monitoring each in real-time while achieving amplitude and time scale of input acceleration that mimic blunt injury cases. These multiplexed, environmental control capabilities enable characterizing the relationships between mechanical impact and cell injury in multivariate biological systems. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 16/999174 |
| ART UNIT | 1799 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/12 (20130101) C12M 23/34 (20130101) C12M 25/04 (20130101) Original (OR) Class C12M 35/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702625 | Rao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore County (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore County (Baltimore, Maryland) |
| INVENTOR(S) | Govind Rao (Ellicott city, Maryland); Yordan Kostov (Columbia, Maryland); Leah Tolosa (Columbia, Maryland); Xudong Ge (Woodstock, Maryland); Douglas Frey (Ellicott City, Maryland) |
| ABSTRACT | A portable and mobile bioprocessing system and method for protein manufacturing that is compact, integrated and suited for on-demand production of any type of proteins and for delivery of the produced proteins to patients or for assay purposes. The portable system and method can also be used for efficient on-demand production of any type of protein with point-of-care delivery. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 17/376439 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/12 (20130101) C12M 47/10 (20130101) Original (OR) Class C12M 47/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702810 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Colt T. Miller (Bloomington, Indiana); Sean P Gish (Bedford, Indiana) |
| ABSTRACT | Provided is a flood barrier for use with HAZMAT materials. The barrier includes a first wall and a second wall joined together at a first end, tape for securing the barrier to a surface to prevent leaks, multiple flexible ribs attached between the first wall and second walls, one or more holes for filling, and a rod that separates an open end of the first and second wall to form a chamber with an open end. Several insulating floats are evenly spaced between the ribs on a bottom surface of the first wall to prevent overflow. A gap filler, such as uncured silicone and tape is used in the transition from a terminal rib to an exposed corner of the barrier. The barrier can withstand high heat for a sustained period of time, is leak-proof, and includes an improved method of sealing corners. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/578657 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Hydraulic Engineering E02B 3/106 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702945 | Heeter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Robert W. Heeter (Noblesville, Indiana); Daniel E. Molnar, Jr. (Lebanon, Indiana) |
| ABSTRACT | A fan case assembly adapted for use with a gas turbine engine includes a fan track liner and an annular case. The fan track liner extends circumferentially at least partway about a central axis of the gas turbine engine. The annular case is configured to support the fan track liner at a radial position relative to the central axis. The fan case assembly further includes an air recirculation duct configured to redirect air around the fan track liner. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 17/560227 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/06 (20130101) Original (OR) Class F01D 25/26 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2240/12 (20130101) F05D 2240/14 (20130101) F05D 2260/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702950 | Farris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | John R. Farris (Bolton, Connecticut); Michael G. McCaffrey (Windsor, Connecticut) |
| ABSTRACT | A method of forming a coating includes disposing a substrate having a plurality of protrusions on a seal and layering a topcoat over the protrusions. The method of forming a coating also includes creating a wear pattern and converting the topcoat. A turbine section includes a casing, a plurality of blades within the casing, and a substrate deposited on the casing having a plurality of protrusions. The turbine also includes an unconverted topcoat disposed over the plurality of protrusions, the topcoat having segmented portions defining a plurality of faults extending from the protrusions through the topcoat. A method of forming a coating includes creating a channel in the coating during an initial rub event and converting the coating during a high-temperature event. Converting the coating includes preserving the channel created during the initial rub event. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/388219 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/007 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/01 (20160101) C23C 4/11 (20160101) C23C 4/18 (20130101) C23C 28/042 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/12 (20130101) Original (OR) Class F01D 11/122 (20130101) F01D 25/005 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/11 (20130101) F05D 2250/294 (20130101) F05D 2300/20 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703075 | Blazek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin M. Blazek (Ridgecrest, California); Lee R. Hardt (Ridgecrest, California) |
| ABSTRACT | Embodiments are directed to first and second structural members that are threadingly-engaged with each other. The first and second structural members are dissimilar strength materials. Each structural member configured with a plurality of threads for the threading engagement. The thread thickness of each thread in the plurality of threads for the first structural member is not equal to the thread thickness of each thread in the plurality of threads for the second structural member. |
| FILED | Thursday, June 04, 2020 |
| APPL NO | 16/892831 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 31/04 (20130101) F16B 37/02 (20130101) Original (OR) Class F16B 37/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703091 | Bartolomeo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Mark E. Bartolomeo (Indianapolis, Indiana) |
| ABSTRACT | In some examples, a cone clutch assembly includes an inner cone member rotationally coupled to a first shaft, the inner cone member defining a first friction surface; and an outer cone member rotationally coupled to a second shaft, the outer cone member defining a second friction surface opposing the first friction surface. The inner cone member and outer cone member may be selectively engaged and disengaged from another. The inner cone member and/or the outer cone member may include a first metallic layer and a second metallic layer separated by an open structure core. The open structure core is configured to allow flow of a fluid between the first metallic layer and the second metallic layer to remove heat from the at least one of the inner cone member or the outer cone member. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/446893 |
| ART UNIT | 3659 — Material and Article Handling |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/32 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 13/26 (20130101) Original (OR) Class F16D 13/66 (20130101) F16D 13/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703257 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Zunfeng Liu (Tianjin, China PRC); Run Wang (Tianjin, China PRC); Jiuke Mu (Plano, Texas); Zhong Wang (Dallas, Texas); Shaoli Fang (Richardson, Texas); Marcio Dias Lima (Richardson, Texas); Ali E. Aliev (Plano, Texas); Na Li (Milwaukee, Wisconsin); Carter S. Haines (Murphy, Texas); Ray H. Baughman (Dallas, Texas) |
| ABSTRACT | Cooling by a twist-untwist process, by a stretch-release process for twisted, coiled, or supercoiled yarns or fibers, and methods and systems thereof. High mechanocaloric cooling results from release of inserted twist or from stretch release for twisted, coiled, or supercoiled fibers, including natural rubber fibers, NiTi wires, and polyethylene fishing line. Twist utilization can increase cooling and cooling efficiencies. A cooler using twist insertion and release can be shorter and smaller in volume than a cooler that requires a large elastomeric elongation. The cooler system can be utilized in mechanochromic textiles and remotely readable tensile and torsional sensors. |
| FILED | Tuesday, September 29, 2020 |
| APPL NO | 17/036018 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/44 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/06 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/0612 (20210801) F03G 7/0615 (20210801) F03G 7/06113 (20210801) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/00 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 10/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2925 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703289 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Nanfang Yu (Fort Lee, New Jersey); Norman Shi (San Jose, California); Meng Tian (Fort Lee, New Jersey) |
| ABSTRACT | Devices for radiative cooling and optical waveguiding are provided, wherein the devices comprise a fabric including one or more fibers extending for a length in a longitudinal direction and a plurality of void structures positioned within each of the one or more fibers and extended over the length of each of the one or more fibers. Each of the plurality of void structures is configured to scatter at least a portion of an electromagnetic radiation received thereon to thereby radiatively cool the object. |
| FILED | Tuesday, February 18, 2020 |
| APPL NO | 16/793668 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/06 (20130101) D01D 1/106 (20130101) D01D 5/06 (20130101) D01D 5/16 (20130101) D01D 5/247 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/04 (20130101) D01F 1/06 (20130101) D01F 1/106 (20130101) D01F 2/00 (20130101) D01F 4/02 (20130101) D01F 6/12 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/022 (20130101) D10B 2401/22 (20130101) D10B 2403/02421 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/003 (20130101) Original (OR) Class F28F 2245/06 (20130101) Optical Elements, Systems, or Apparatus G02B 6/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/25 (20150115) Y10T 428/2915 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703318 | Drexler |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kyle Robert Drexler (San Diego, California) |
| ABSTRACT | A homodyne encoder system has adaptive matching of path lengths. Primary apertures receive light from a target. An optical spreader spreads apart the light passing through the primary apertures by at least a factor of two times a baseline separation of the primary apertures. The optical spreader includes a plurality of actuators for modifying the path lengths within the homodyne encoder system through the primary apertures to a detector. A focusing optic focuses the light from the optical spreader at the detector. The detector detects an image of the target with the light from the focusing optic. |
| FILED | Thursday, February 24, 2022 |
| APPL NO | 17/679423 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/0209 (20130101) G01B 9/02057 (20130101) Original (OR) Class G01B 9/02084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703321 | Adelson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Edward Adelson (Winchester, Massachusetts); Branden Romero (Brighton, Massachusetts); Filipe Fernandes Veiga (Cambridge, Massachusetts) |
| ABSTRACT | A retrographic sensor includes a transparent structure, a transparent elastomeric pad, and an at least partially reflective layer. One or more light sources emit light into a side surface of the transparent structure. The light undergoes internal reflection in the transparent structure and is reflected toward a camera oriented toward the transparent structure. The at least partially reflective layer may be semi-specular in some embodiments. |
| FILED | Thursday, October 15, 2020 |
| APPL NO | 17/071301 |
| ART UNIT | 2627 — Selective Visual Display Systems |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/24 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/24 (20130101) Electric Digital Data Processing G06F 3/016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703330 | Shkel et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Andrei M. Shkel (Irvine, California); Mohammad H. Asadian Ardakani (Irvine, California); Yusheng Wang (Irvine, California) |
| ABSTRACT | A dual-shell architecture and methods of fabrication of fused quartz resonators is disclosed. The architecture may include two encapsulated and concentric cavities using plasma-activated wafer bonding followed by the high-temperature glassblowing. The dual-shell architecture can provide a protective shield as well as a “fixed-fixed” anchor for the sensing element of the resonators. Structures can be instrumented to operate as a resonator, a gyroscope, or other vibratory sensor and for precision operation in a harsh environment. Methods for fabricating a dual-shell resonator structure can include pre-etching cavities on a cap wafer, pre-etching cavities on a device wafer, bonding the device wafer to a substrate wafer to form a substrate pair and aligning and bonding the cap wafer to the substrate pair to form a wafer stack with aligned cavities including a cap cavity and a device cavity. The wafer stack may be glassblown to form a dual-shell structure. |
| FILED | Tuesday, March 31, 2020 |
| APPL NO | 16/836387 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0051 (20130101) B81B 7/0016 (20130101) B81B 2201/0242 (20130101) B81B 2201/0271 (20130101) B81B 2203/0127 (20130101) B81B 2203/0172 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00158 (20130101) B81C 1/00182 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/5691 (20130101) G01C 19/5719 (20130101) Original (OR) Class Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/0072 (20130101) H03H 9/1057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703331 | Najafi et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Khalil Najafi (Ann Arbor, Michigan); Sajal Singh (Ann Arbor, Michigan); Jae Yoong Cho (Ann Arbor, Michigan) |
| ABSTRACT | Three-dimensional (3D) micro-scale shells are presented with openings of various sizes and geometries on the surface. The shell consist of a suspended ring-shaped resonator, multiple support beams, a support post, and a cap region that connects the support beams to the support post. Shells with openings of various sizes and geometries allow the creation of micro electromechanical systems (MEMS) sensors and actuators with a wide range of engineered mechanical and electrical properties. The openings on the shell surface can, for example, control the mechanical quality factor (Q) and resonance frequencies of the shell when the shell is used as a suspended proof mass of a mechanical resonator of a vibratory gyroscope. The shells can also serve as mechanical supporting layers and/or an electrode connection layer for MEMS actuators and sensors that use 3D shells as proof masses. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/205562 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 2201/0242 (20130101) B81B 2201/0271 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00444 (20130101) B81C 2201/0143 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/005 (20220101) G01C 19/5684 (20130101) G01C 19/5691 (20130101) G01C 19/5783 (20130101) Original (OR) Class Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/0072 (20130101) H03H 9/02259 (20130101) H03H 9/2405 (20130101) H03H 2009/02496 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703453 | Meyer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Jerry R. Meyer (Catonsville, Maryland); Igor Vurgaftman (Severna Park, Maryland); Chadwick Lawrence Canedy (Washington, District of Columbia); William W. Bewley (Falls Church, Virginia); Chul Soo Kim (Springfield, Virginia); Charles D. Merritt (Fairfax, Virginia); Michael V. Warren (Arlington, Virginia); R. Joseph Weiblen (Washington, District of Columbia); Mijin Kim (Springfield, Virginia) |
| ABSTRACT | Building blocks are provided for on-chip chemical sensors and other highly-compact photonic integrated circuits combining interband or quantum cascade lasers and detectors with passive waveguides and other components integrated on a III-V or silicon. A MWIR or LWIR laser source is evanescently coupled into a passive extended or resonant-cavity waveguide that provides evanescent coupling to a sample gas (or liquid) for spectroscopic chemical sensing. In the case of an ICL, the uppermost layer of this passive waveguide has a relatively high index of refraction that enables it to form the core of the waveguide, while the ambient air, consisting of the sample gas, functions as the top cladding layer. A fraction of the propagating light beam is absorbed by the sample gas if it contains a chemical species having a fingerprint absorption feature within the spectral linewidth of the laser emission. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/407230 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/1895 (20130101) G01J 3/2803 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/27 (20130101) G01N 21/59 (20130101) Original (OR) Class G01N 21/255 (20130101) G01N 2201/0612 (20130101) Optical Elements, Systems, or Apparatus G02B 6/102 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/062 (20130101) H01S 5/101 (20130101) H01S 5/125 (20130101) H01S 5/0215 (20130101) H01S 5/0262 (20130101) H01S 5/0287 (20130101) H01S 5/343 (20130101) H01S 5/0421 (20130101) H01S 5/0612 (20130101) H01S 5/2063 (20130101) H01S 5/2206 (20130101) H01S 5/3402 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703601 | Bobrek et al. |
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| FUNDED BY |
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| APPLICANT(S) | FAIRWINDS TECHNOLOGIES, LLC (Annapolis, Maryland) |
| ASSIGNEE(S) | CANNON ERGOS S.P.A. (, None) |
| INVENTOR(S) | Pavlo Bobrek (Bradenton, Florida); Timothy Hillner (Middletown, Delaware); Glenn Link (Odenton, Maryland) |
| ABSTRACT | A signal processing apparatus and method provides the ability to dynamically select a subset of subcarriers from a received frequency division multiplex (FDM), select which subsets of subcarriers are coherently combined per satellite, and translate the selected subcarriers into a FDM having a smaller bandwidth. There are at least two first phase aligners, a digital cross-connect, and at least two second phase aligners. The first and second phase aligners are configured to receive a pair of in-phase and quadrature pairs and provide automatic gain control and coherent combing of the pairs. The digital cross-connect is configured to receive the in-phase and quadrature pairs from the two phase aligners and associate any in-phase and quadrature pair with another. Preferably, the apparatus further includes dual front-end digital channelizers configured to convert signals into an in-phase and quadrature pairs which are input to the first phase aligners. |
| FILED | Monday, January 17, 2022 |
| APPL NO | 17/577308 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/44 (20130101) Original (OR) Class G01S 19/45 (20130101) G01S 19/423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703643 | Coolbaugh et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Douglas Coolbaugh (Highland, New York); Thomas Adam (Slingerlands, New York); Gerald L. Leake (Delmar, New York) |
| ABSTRACT | A photonic structure can include in one aspect one or more waveguides formed by patterning of waveguiding material adapted to propagate light energy. Such waveguiding material may include one or more of silicon (single-, poly-, or non-crystalline) and silicon nitride. |
| FILED | Tuesday, December 17, 2019 |
| APPL NO | 16/717737 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/13 (20130101) Original (OR) Class G02B 6/43 (20130101) G02B 6/132 (20130101) G02B 6/136 (20130101) G02B 6/1347 (20130101) G02B 6/12002 (20130101) G02B 2006/121 (20130101) G02B 2006/12061 (20130101) G02B 2006/12104 (20130101) G02B 2006/12123 (20130101) G02B 2006/12169 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0245 (20130101) H01L 21/0262 (20130101) H01L 21/2033 (20130101) H01L 21/2053 (20130101) H01L 21/02381 (20130101) H01L 21/02505 (20130101) H01L 21/02532 (20130101) H01L 21/02573 (20130101) H01L 21/02639 (20130101) H01L 27/14625 (20130101) H01L 27/14629 (20130101) H01L 31/028 (20130101) H01L 31/105 (20130101) H01L 31/0232 (20130101) H01L 31/1808 (20130101) H01L 31/02327 (20130101) H01L 31/022408 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) Y02E 10/547 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703882 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | U.S. Government as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Melanie Anderson (Redmond, Washington); Kevin Brink (Fort Walton Beach, Florida); Thomas Daniel (Seattle, Washington); Sawyer Fuller (Seattle, Washington); Joseph Sullivan (Redmond, Washington); Jennifer Talley (Niceville, Florida) |
| ABSTRACT | A bio-hybrid odor-localizing autonomous air vehicle includes an airborne robotic platform having a navigation platform, a wireless transmitter communicatively coupled to a management console, and a biological sensor mounted on the airborne robotic platform that reacts to at least one olfactory odor. A controller is communicatively coupled to the airborne robotic platform, the navigation platform, and the biological sensor. The controller monitors the biological sensor. In response to the biological sensor detecting the at least one olfactory odor, the controller directs the airborne platform to three-dimensionally map an olfactory plume of the at least one olfactory odor using an olfactory-driven search pattern. The controller stores the three-dimensional map for later retrieval or transmits the three-dimensional map of the olfactory plume to the management console via the wireless transmitter. |
| FILED | Wednesday, May 20, 2020 |
| APPL NO | 16/879296 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 39/028 (20130101) B64C 2201/127 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0038 (20130101) G05D 1/0044 (20130101) G05D 1/0274 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/40 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704155 | Vega et al. |
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| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machine Corporation (Armonk, New York) |
| INVENTOR(S) | Augusto Vega (Mount Vernon, New York); Alper Buyuktosunoglu (White Plains, New York); Hubertus Franke (Cortlandt Manor, New York); John-David Wellman (Hopewell Junction, New York); Pradip Bose (Yorktown Heights, New York); Robert Matthew Senger (Tarrytown, New York); Aporva Amarnath (Ann Arbor, Michigan) |
| ABSTRACT | Described are techniques for scheduling tasks on a heterogeneous system on a chip (SoC). The techniques including receiving a directed acyclic graph at a meta pre-processor associated with a heterogeneous SoC and communicatively coupled to a scheduler, wherein the directed acyclic graph corresponds to a control flow graph of tasks associated with an application executed by the heterogeneous SoC. The techniques further including determining a rank for a respective task in the directed acyclic graph, wherein the rank is based on a priority of the respective task and a slack in the directed acyclic graph. The techniques further including providing the respective task to the scheduler for execution on the heterogeneous SoC according to the rank. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/917975 |
| ART UNIT | 3687 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4893 (20130101) Original (OR) Class G06F 16/9024 (20190101) G06F 2209/486 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704946 | Hassaan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Syed Hassaan (Tempe, Arizona); Qiang Shen (Tempe, Arizona); Sze Zheng Yong (Mesa, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Syed Hassaan (Tempe, Arizona); Qiang Shen (Tempe, Arizona); Sze Zheng Yong (Mesa, Arizona) |
| ABSTRACT | The present disclosure provides a method in a data processing system that includes at least one processor and at least one memory. The at least one memory includes instructions executed by the at least one processor to implement a bounded-error estimator system. The method includes receiving information about a plurality of vehicle states of a vehicle from at least one sensor, determining that the information is missing data about at least one vehicle state of the plurality of vehicle states, and determining an estimated vehicle state associated with a final vehicle state. Determining the estimated vehicle state includes calculating a plurality of augmented states for each of the vehicle states included in the plurality of vehicle states and calculating the estimated vehicle state based on the plurality of augmented states. The estimated vehicle state is provided to a vehicle control system of the vehicle. |
| FILED | Thursday, July 09, 2020 |
| APPL NO | 16/925216 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 16/215 (20190101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/008 (20130101) G07C 5/0816 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705527 | Jiang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Peng Jiang (Gainesville, Florida); Zhuxiao Gu (Gainesville, Florida); Ruwen Tan (Gainesville, Florida) |
| ABSTRACT | Embodiments of the present disclosure provide for methods of making substrates having an (AR) antireflective layer, substrates having an antireflective layer, devices including a substrate having an antireflective layer, and the like. The AR layer can have a total specular reflection of less than 10% at a wavelength of about 400-800 nm, and a height of about 500-1000 nm. |
| FILED | Tuesday, December 18, 2018 |
| APPL NO | 16/956029 |
| ART UNIT | 2896 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/118 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/186 (20130101) H01L 31/02168 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705535 | Jonker et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Berend T. Jonker (Davidsonville, Maryland); Matthew R. Rosenberger (Arlington, Virginia); Hsun-Jen Chuang (Alexandria, Virginia); Joshua R. Hendrickson (Dayton, Ohio); Chandriker Kavir Dass (Dayton, Ohio) |
| ABSTRACT | A nano-indent process for creating a single photon emitter in a two-dimensional materials platform comprising the steps of providing a substrate, providing a layer of polymer, providing a layer of two-dimensional material, utilizing a proximal probe, applying mechanical stress to the layer of two-dimensional material and to the layer of polymer, deforming the layer of two-dimensional material and the layer of polymer, and forming a nano-indent in the two-dimensional material. A single photon emitter in a two-dimensional materials platform comprising a substrate, a deformable polymer film, a two-dimensional material, and a nano-indent in the two-dimensional material. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/919024 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 40/00 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/16 (20130101) G01Q 60/38 (20130101) G01Q 80/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/856 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705943 | Sagduyu et al. |
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| FUNDED BY |
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| APPLICANT(S) | INTELLIGENT AUTOMATION, LLC (Rockville, Maryland) |
| ASSIGNEE(S) | INTELLIGENT AUTOMATION, LLC (Rockville, Maryland) |
| INVENTOR(S) | Yalin Evren Sagduyu (Gaithersburg, Maryland); Tugba Erpek (McLean, Virginia); Yi Shi (Boyds, Maryland); Satya Ponnaluri (Gaithersburg, Maryland) |
| ABSTRACT | A network control and rate optimization solution for multiuser multiple input multiple output (MU-MIMO) communications in wireless networks. This solution is decentralized and includes scheduling and routing of the MU-MIMO communication links that adapt to dynamic channel, interference, and traffic conditions. The ergodic sum rates of MIMO multiple access channel (MAC) and interference channel (IC) configurations are analyzed by considering the error, and overhead effects due to channel estimation (training) and quantization (feedback). By taking practical considerations such as channel estimation, quantization error and in-network interference into account, the rate gain is shown with an increasing number of antennas compared with single-input single-output (SISO) systems. A distributed channel access protocol to select and activate MU-MIMO configurations is presented with the maximum achievable sum rates using local information on channel, interference, and traffic conditions. The scheduling algorithm is extended to routing via a cross-layer solution based on a decentralized version of the backpressure algorithm. After accounting for the control message overhead, it is shown that the proposed MU-MIMO scheduling and routing solution improves the stable throughput over the minimum distance routing based on frequency of encounters and single user MIMO communications in a mobile ad hoc network (MANET) setting. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/007970 |
| ART UNIT | 2476 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/0452 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0202 (20130101) H04L 41/0896 (20130101) Wireless Communication Networks H04W 84/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11706221 | Spiegel |
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| FUNDED BY |
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| APPLICANT(S) | Two Six Labs, LLC (Arlington, Virginia) |
| ASSIGNEE(S) | Two Six Labs, LLC (Arlington, Virginia) |
| INVENTOR(S) | Michael Spiegel (Vienna, Virginia) |
| ABSTRACT | A shared memory system for providing unidirectional communication across a security threshold defined by producer and consumer of a message at different security levels. A unidirectional shared memory element is accessible for read and write access by the message producer (sender), and the consumer (receiver) has only read access. Transmission logic ensures atomic receipt of the message if it is received, as the receiver cannot issue an acknowledgement to the sender as in conventional electronic interfaces. An arrangement of indices and counters allows asynchronous operation by the sender and receiver, as messages may queue up in the shared memory if the producer exceeds the consumer. In the event of a failure, anomaly, or resource overrun, it is known that messages that were received were received in entirety; in other words, atomicity is preserved. |
| FILED | Tuesday, May 25, 2021 |
| APPL NO | 17/329551 |
| ART UNIT | 2499 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/101 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11706848 | Kessler et al. |
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| FUNDED BY |
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| APPLICANT(S) | Metis Design Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Metis Design Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Seth S. Kessler (Newton, Massachusetts); Gregory A. Thomas (San Francisco, California); Christopher T. Dunn (Salem, Massachusetts); Michael Borgen (Wilmington, Massachusetts); Brian L. Wardle (Lexington, Massachusetts) |
| ABSTRACT | A multifunctional assembly having a resistive element a conductive element in electrical communication with the resistive element, the conductive element defining at least one of a plurality of multifunctional zones of the resistive element, wherein the conductive element is configured to direct a flow of electricity across at least one of the plurality of multifunctional zones of the resistive element in a preselected manner. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576019 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Resistors H01C 13/00 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/33 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 1/0236 (20130101) H05B 3/20 (20130101) H05B 3/145 (20130101) H05B 3/265 (20130101) H05B 3/267 (20130101) H05B 6/101 (20130101) Original (OR) Class H05B 2203/011 (20130101) H05B 2203/013 (20130101) H05B 2203/016 (20130101) H05B 2203/017 (20130101) H05B 2214/02 (20130101) H05B 2214/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11701046 | Sridhar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Srinivas Sridhar (Newton, Massachusetts); Craig Versek (Cranston, Rhode Island); Peter Bex (Concord, Massachusetts) |
| ABSTRACT | A portable wireless neuromonitoring device can be used to diagnose and/or treat conditions of the brain and vision system. The device includes a sensor unit mountable on the head of a human subject and capable of recording signals from the brain in EEG and/or EFEG (electric field encephalography) mode, and the device can be used for simultaneous stimulus display and recording with latency of less than 1 millisecond. The device also includes electrodes that allow rapid set-up and measurement with low impedance contact with the scalp. The device can also be used in conjunction with virtual reality or alternate reality environments. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 16/347049 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/10 (20130101) A61B 5/162 (20130101) A61B 5/291 (20210101) Original (OR) Class A61B 5/378 (20210101) A61B 5/742 (20130101) A61B 5/4082 (20130101) A61B 5/4088 (20130101) A61B 5/6803 (20130101) A61B 5/6831 (20130101) A61B 5/7264 (20130101) A61B 2562/14 (20130101) A61B 2562/0209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11701092 — Automated ultrasound apparatus and methods to non-invasively monitor fluid responsiveness
| US 11701092 | Kruger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Grant Kruger (Ann Arbor, Michigan); Torben K. Becker (Gainesville, Florida); Nikhil Theyyunni (Ann Arbor, Michigan); Ross Kessler (Ann Arbor, Michigan); Bradley Plummer (Ann Arbor, Michigan); Matthew Tafoya (Oakland, California); Chelsea Tafoya (Oakland, California); Steven E. Harte (Livonia, Michigan) |
| ABSTRACT | A fully automated ultrasound apparatus includes a sensor or probe which can be initially manually attached to a side of the neck of a patient, an ultrasound interface to control the sensor and periodically acquire raw ultrasound data, a signal and image processing system to autonomously convert the raw ultrasound data into a measurement that is useful to physicians, and a display to relay the current measurements and measurement history to provide data trends. The sensor can include one or more ultrasound transducers built into a housing. A disposable component can serve to secure the sensor to the neck of the patient and to provide a coupling medium between the sensor and the skin of the patient. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 16/611470 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/02 (20130101) A61B 8/06 (20130101) A61B 8/4236 (20130101) A61B 8/4254 (20130101) A61B 8/5207 (20130101) Original (OR) Class A61B 8/5223 (20130101) A61B 8/5276 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701232 | Guo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Ting Guo (Cambridge, Massachusetts); John Patrick Fisher (Kensington, Maryland); Hannah Baker (Baltimore, Maryland); Max Jonah Lerman (Silver Spring, Maryland); Robert Choe (Arlington, Virginia) |
| ABSTRACT | An implantable acellular polymeric scaffold device functionalized with aggrecan is provided. Also provided are methods of fabricating a polymeric scaffold device, including methods of fabricating the scaffold device via 3D printing. Methods of treating a cartilage defect in a subject in need thereof comprise application of the disclosed scaffold device in combination with microfracture procedures. A specialized lid for a centrifugation well plate is also provided. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743315 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/30756 (20130101) Original (OR) Class A61F 2002/30766 (20130101) A61F 2002/30985 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701494 | Dezfulian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Cameron Dezfulian (Pittsburgh, Pennsylvania); William W. Clark (Wexford, Pennsylvania); Ehsan Qaium (Pittsburgh, Pennsylvania); Dennis Wist (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed catheter insertion systems enable the user to identify the location of the needle based on the electrical properties of subcutaneous tissue relative the electrical properties of other fluids such as blood or air. Disclosed systems can include one or more of the following features: 1) the catheter assembly is modular (e.g., the catheter can be connected and disconnected from the detection unit at will); 2) the detection unit employs an electrical circuit that allows for the discernment between subcutaneous tissue and blood; 3) the system assists the end user with catheter advancement. Some embodiments can be used to insert catheters into a spaces where the needle passes first through subcutaneous fat and muscle before entering fluid or air. |
| FILED | Thursday, July 05, 2018 |
| APPL NO | 16/623611 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0606 (20130101) Original (OR) Class A61M 25/09041 (20130101) A61M 2205/273 (20130101) A61M 2205/581 (20130101) A61M 2205/582 (20130101) A61M 2205/583 (20130101) A61M 2205/3538 (20130101) A61M 2205/3553 (20130101) A61M 2205/3653 (20130101) A61M 2205/6027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701656 | Cai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Dawen Cai (Ann Arbor, Michigan); Daniel Nunez (Ann Arbor, Michigan); Katsuo Kurabayashi (Ann Arbor, Michigan); Meng-Ting Chung (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are systems, methods, and articles of manufacture for collecting and merging two different size droplets using a substrate comprising a plurality of trapping sites. In certain embodiments, provided herein are systems composed of a plurality of larger droplets and smaller droplets and a substrate comprising a plurality of trapping sites where each trapping site is configured to trap only one of the larger droplets and only one of the smaller droplets when the larger droplet is already present at the trapping site. In particular embodiments, the larger and/or smaller droplets are sorted prior to being contacted with the substrate to ensure they contain the desired component (e.g., cell or barcoded bead). In other embodiments, each trapping site is composed of one or multiple fluidically linked capture wells. In some embodiments, collected larger and smaller droplets are merged (e.g., via a demulsifier or electricity). |
| FILED | Wednesday, January 02, 2019 |
| APPL NO | 16/957338 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 3/502792 (20130101) B01L 2200/16 (20130101) B01L 2200/0673 (20130101) B01L 2300/12 (20130101) B01L 2300/0645 (20130101) B01L 2300/0654 (20130101) B01L 2300/0819 (20130101) B01L 2400/0415 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702495 | Le Floch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Paul Le Floch (Cambridge, Massachusetts); Xi Yao (Cambridge, Massachusetts); Qihan Liu (Cambridge, Massachusetts); Guodong Nian (Hangzhou, China PRC); Canhui Yang (Somerville, Massachusetts); Zhigang Suo (Lexington, Massachusetts) |
| ABSTRACT | A polymer composite of dissimilar polymers covalently bonded at the interface is disclosed. A method for bonding dissimilar polymers includes providing a first precursor to a hydrogel polymer network comprising a first coupling agent; providing a second precursor to a second polymer network comprising a second coupling agent, wherein the hydrogel polymer network and the second polymer network are different; initiating polymerization of the first precursor to form a hydrogel polymer network, wherein the first coupling agent is incorporated into the polymer network with a negligible amount of condensation; initiating polymerization of the second precursor to form a second polymer network, wherein the second coupling agent is incorporated into the second polymer network with a negligible amount of condensation; contacting one of the first hydrogel precursor or the hydrogel polymer network with one of the second polymer precursor or second polymer networks and initiating condensation between the first and second coupling agents to form a covalent bond. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/634039 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/56 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/38 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 8/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702543 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander A. Green (Scottsdale, Arizona); Matthew Gilliam (Tempe, Arizona); Ahmed Yousaf (Hillsboro, Oregon); Qing Hua Wang (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Alexander A. Green (Scottsdale, Arizona); Matthew Gilliam (Tempe, Arizona); Ahmed Yousaf (Hillsboro, Oregon); Qing Hua Wang (Scottsdale, Arizona) |
| ABSTRACT | A polymerizable composition for 3D printing includes a photocurable polymer resin and metal diboride nanosheets. The resulting polymer nanocomposite includes a polymer matrix and metal diboride nanosheets dispersed throughout the polymer matrix. A method of synthesizing a nanomaterial-containing resin for 3D printing includes preparing a dispersion of metal diboride nanosheets in a solvent, and combining the dispersion with a liquid polymer resin to yield the nanomaterial-containing resin. A method of fabricating a nanocomposite structure from the nanomaterial-containing resin includes providing the nanomaterial-containing resin to a three-dimensional printer, forming a three-dimensional structure with the three-dimensional printer, and processing the three-dimensional structure to yield the nanocomposite structure. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 16/832225 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/56 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/38 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702667 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Yinong Yang (State College, Pennsylvania); Kabin Xie (Wuhan, China PRC) |
| ABSTRACT | The invention includes materials and methods to generate numerous small RNAs from one polynucleotide construct (synthetic gene) to facilitate RNA-guided multiplex genome editing, modification, inhibition of expression and other RNA-based technologies. The synthetic gene/polynucleotide construct encodes polycistronic RNA components separated by tRNAs, and preferably also includes regulatory components such as a promoter or terminator to form an expression cassette. Once transcribed in a cell, the transcript is processed by the cell to multiple RNA molecules by the endogenous tRNA processing system. The system can be sued for any RNA based gene manipulation method including RNA-mediated genome editing, artificial microRNA mediated gene silencing, small RNA mediated genetic manipulation, double-stranded RNA mediated gene silencing, antisense mechanisms and the like. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 16/386903 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/8213 (20130101) Original (OR) Class C12N 15/8216 (20130101) C12N 15/8218 (20130101) C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2310/51 (20130101) C12N 2330/31 (20130101) C12N 2330/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703285 | Skop |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Helen Skop (Skokie, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Helen Skop (Skokie, Illinois) |
| ABSTRACT | An energy exchanger for exchanging energy between a hot flow and a cold flow may comprise a hot flow section and a cold flow section, each of the sections comprising the same quantity of channels having variable cross sections. The inlets of the hot flow channels may be juxtaposed to the outlets of the cold flow channels and the outlets of the hot flow channels may be juxtaposed to the inlets of the cold flow channels such that the hot and cold flows move in opposing directions. The energy exchanger may further comprise a liquid distribution system and a common interface between each hot flow channel and a corresponding cold flow channel with an exponentially varying surface area adapted for exchanging latent energy released through condensation in the hot flow section and absorbed through evaporation in the cold flow section. |
| FILED | Monday, February 27, 2023 |
| APPL NO | 18/114396 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 9/04 (20130101) F28D 15/02 (20130101) F28D 20/02 (20130101) Original (OR) Class F28D 21/0003 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703429 | Godfrin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NANOSOFT, LLC. (Coventry, Rhode Island) |
| ASSIGNEE(S) | NanoSoft, LLC (Coventry, Rhode Island) |
| INVENTOR(S) | Michael Godfrin (Narragansett, Rhode Island); Michael Franzblau (Scituate, Rhode Island) |
| ABSTRACT | A method includes introducing a fluidic sample into the void volume and onto the surface of a porous material, bringing the porous material into contact with a hydrophilic substrate compatible with a cryogenic Transmission Electron Microscope, separating the porous material from the substrate, and transferring a portion of the sample from the porous material to the substrate between their contact and separation. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346758 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) Original (OR) Class G01N 23/04 (20130101) G01N 2223/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703476 | Wanunu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | NORTHEASTERN UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Meni Wanunu (Needham, Massachusetts); Mohammadamin Alibakhshi (Boston, Massachusetts); Xinqi Kang (Boston, Massachusetts); Zhuoyu Zhang (Brooklyn, New York) |
| ABSTRACT | An apparatus is provided for sensing a molecule in a sample. The apparatus utilizes an electric field to draw molecules from a first chamber through an aperture, defined by a chemical layer, into a second chamber. The apparatus can detect a DNA molecule with, for example, 4, 5, or 6 unique base pairs. As molecules pass through the aperture, a sensor detects or measures a change in an electric parameter used to generate the electric field, thereafter translating the change in the electric parameter into information about the molecule. A divider element separates the first and second chambers and supports a chemical layer defining the aperture. The apparatus enables detection or measurement of molecules over prolonged time at a higher electric field strength than other nanopores, due to a combination of the shape of the divider, structural elements thereon, and thickness of the chemical layer at the aperture. |
| FILED | Wednesday, October 28, 2020 |
| APPL NO | 17/083264 |
| ART UNIT | 1758 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 2300/0645 (20130101) B01L 2300/0832 (20130101) B01L 2400/0406 (20130101) B01L 2400/0415 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4166 (20130101) Original (OR) Class G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703555 | Dubroca et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Thierry Dubroca (Tallahassee, Florida); Bianca Trociewitz (Tallahassee, Florida); Johannes McKay (Tallahassee, Florida); Frederic Mentink-Vigier (Tallahassee, Florida) |
| ABSTRACT | Apparatuses and methods for removing caps, such as NMR rotor caps. The apparatuses and methods may permit caps to be removed in a manner that minimizes damage to equipment and instruments. The apparatuses may include a plate defining an aperture, and two screws arranged in the plate, such as a tightening screw and at least one pushing screw. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/104057 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/307 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703855 | Chowdhary et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Girish Chowdhary (Champaign, Illinois); Chinmay P. Soman (Urbana, Illinois); Beau David Barber (Ogden, Illinois) |
| ABSTRACT | The present disclosure provides a system for monitoring unstructured environments. A predetermined path can be determined according to an assignment of geolocations to one or more agronomically anomalous target areas, where the one or more agronomically anomalous target areas are determined according to an analysis of a plurality of first images that automatically identifies a target area that deviates from a determination of an average of the plurality of first images that represents an anomalous place within a predetermined area, where the plurality of first images of the predetermined area are captured by a camera during a flight over the predetermined area. A camera of an unmanned vehicle can capture at least one second image of the one or more agronomically anomalous target areas as the unmanned vehicle travels along the predetermined path. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 17/522699 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0038 (20130101) Original (OR) Class Electric Digital Data Processing G06F 16/29 (20190101) G06F 18/2178 (20230101) Image or Video Recognition or Understanding G06V 10/22 (20220101) G06V 10/763 (20220101) G06V 10/7784 (20220101) G06V 20/17 (20220101) G06V 20/188 (20220101) G06V 20/194 (20220101) Traffic Control Systems G08G 5/0039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11704129 — Transparent interpretation and integration of layered software architecture event streams
| US 11704129 | Yuile et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Adam Bates Yuile (Champaign, Illinois); Wajih Ul Hassan (Champaign, Illinois); Mohammad Noureddine (Urbana, Illinois) |
| ABSTRACT | A computerized method includes analyzing program code, including a control flow graph, of one or more applications that are executable by an operating system of a computing device to determine event-logging functions of the program code that generate event logs; extracting, by the processing device based on the event-logging functions, log message strings from the program code that describes event-logging statements; identifying, by the processing device, via control flow analysis, possible control flow paths of the log message strings through the control flow graph; storing, in a database accessible by the processing device, the possible control flow paths; and inputting, by the processing device into a log parser, the possible control flow paths of the log message strings to facilitate interpretation of application events during runtime execution of the one or more applications. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/247038 |
| ART UNIT | 2153 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) G06F 9/3005 (20130101) Original (OR) Class G06F 9/3017 (20130101) G06F 16/1734 (20190101) G06F 40/205 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704457 | Riasi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CINCINNATI (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Mohammad Sadegh Riasi (Cincinnati, Ohio); Lilit Yeghiazarian (Cincinnati, Ohio) |
| ABSTRACT | Methods, software, and apparatuses for accurate and computationally fast and efficient topologic and geometric characterization of porous material or medium, flow characterization of porous material or medium, and porous material or medium design are described. |
| FILED | Friday, June 15, 2018 |
| APPL NO | 16/009757 |
| ART UNIT | 2148 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) G06F 30/23 (20200101) Original (OR) Class G06F 2111/10 (20200101) Image Data Processing or Generation, in General G06T 7/0004 (20130101) G06T 7/62 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704460 | Jin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Yier Jin (Gainesville, Florida); Shaojie Zhang (Orlando, Florida); James Geist (Oviedo, Florida); Travis Meade (Orlando, Florida); Jason Liam Portillo (San Jose, California) |
| ABSTRACT | Embodiments herein provide for reverse engineering of integrated circuits (ICs) for design verification. In example embodiments, an apparatus receives a gate-level netlist for an integrated circuit (IC), generates a list of equivalence classes related to signals included in the gate-level netlist, determines control signals of the gate-level netlist based at least in part on the list of equivalence classes, determines a logic flow of a finite state transducer (FST) based at least in part on the control signals, and generates register transfer level (RTL) source code for the IC based on the FST. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/343231 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 30/33 (20200101) Original (OR) Class G06F 30/327 (20200101) G06F 2115/08 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704473 | Tashman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Craig S. Tashman (South Salem, New York); W. Keith Edwards (Atlanta, Georgia) |
| ABSTRACT | Review systems and methods facilitate active reading by providing a flexible environment in which users can examine documents. A review system can comprise a virtual workspace, a document view region, a preview region, and optional document objects. The virtual workspace can simulate a desktop or other physical workspace. The document view region can display a portion of an open document at a magnification sufficient for reading. The preview region can display the document at a magnification sufficient to enable the general layout of the entire document to be determined. The document objects can be created from the document through tools of the review system. These document objects can be independently moveable throughout the virtual workspace as needed to facilitate the user's active reading process. |
| FILED | Monday, April 22, 2019 |
| APPL NO | 16/391003 |
| ART UNIT | 2178 — Graphical User Interface and Document Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0483 (20130101) G06F 3/0485 (20130101) G06F 3/04883 (20130101) G06F 40/103 (20200101) Original (OR) Class G06F 40/169 (20200101) G06F 2203/04808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705373 | Moody et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Michael J. Moody (Chicago, Illinois); Lincoln J. Lauhon (Chicago, Illinois); Ju Ying Shang (Romeoville, Illinois) |
| ABSTRACT | A system and method for performing in-situ measurements of semiconductor devices during chemical vapor deposition (CVD) includes disposing a chip carrier within a sealed chamber of a reactor for carrying out in-situ monitoring of partially fabricated semiconductor devices. The chip carrier includes a plurality of metallized bonding pads disposed along both peripheral edges on a same surface of the base for making electrical connections to metallized pads or contacts on the semiconductor device through bonding wires. Each of the plurality of metallized bonding pads disposed along both peripheral edges is electrically connected to each other as a pair through electrically connecting to a corresponding pair of ports which are disposed along both peripheral edges of the chip carrier. In-situ monitoring of the partially fabricated semiconductor device is performed through connecting the plurality of ports on the chip carrier to an external source-measure unit through a connector and wire harness. |
| FILED | Wednesday, March 10, 2021 |
| APPL NO | 17/197654 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/52 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2621 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/67253 (20130101) H01L 22/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705527 | Jiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Peng Jiang (Gainesville, Florida); Zhuxiao Gu (Gainesville, Florida); Ruwen Tan (Gainesville, Florida) |
| ABSTRACT | Embodiments of the present disclosure provide for methods of making substrates having an (AR) antireflective layer, substrates having an antireflective layer, devices including a substrate having an antireflective layer, and the like. The AR layer can have a total specular reflection of less than 10% at a wavelength of about 400-800 nm, and a height of about 500-1000 nm. |
| FILED | Tuesday, December 18, 2018 |
| APPL NO | 16/956029 |
| ART UNIT | 2896 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/118 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/186 (20130101) H01L 31/02168 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705639 | Mendis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | Brown University (Providence, Rhode Island) |
| INVENTOR(S) | Rajind Mendis (Providence, Rhode Island); Masaya Nagai (Osaka, Japan); Daniel M. Mittleman (Providence, Rhode Island) |
| ABSTRACT | An isolator based on a waveguide-based artificial dielectric medium is scalable to a range of desired terahertz frequencies, has non-reciprocal transmission and provides low insertion loss and high isolation at various tunable terahertz frequencies, far exceeding the performance of other terahertz isolators, and rivaling that of commercial optical isolators based on the Faraday effect. This approach offers a promising new route for polarization control of free-space terahertz beams in various instrumentation applications. Artificial dielectrics are man-made media that mimic properties of naturally occurring dielectric media, or even manifest properties that cannot generally occur in nature. A simple and effective strategy implements a polarizing-beam-splitter and a quarter wave plate to form a highly effective isolator. Performance of the device is believed to exceed that of any other experimentally demonstrated method for isolation of back-reflections for terahertz beams. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 16/494221 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/3008 (20130101) G02B 5/3058 (20130101) G02B 27/285 (20130101) Antennas, i.e Radio Aerials H01Q 15/242 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705720 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Fei Wang (Knoxville, Tennessee); Edward A. Jones (Knoxville, Tennessee) |
| ABSTRACT | A power converter circuit includes a switch including a field effect transistor, the field effect transistor being a wide bandgap field effect transistor and being configured to maintain an on operational state responsive to a maintenance signal received through a gate terminal, a current sensing circuit that is configured to estimate a drain terminal current of the field effect transistor responsive to a voltage between the gate terminal of the field effect transistor and a source terminal of the field effect transistor, and a gate driving circuit that is configured to generate the maintenance signal responsive to the estimate of the drain terminal current. |
| FILED | Thursday, May 19, 2022 |
| APPL NO | 17/664163 |
| ART UNIT | 2839 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/1066 (20130101) H01L 29/2003 (20130101) H01L 29/7787 (20130101) H01L 29/41766 (20130101) Emergency Protective Circuit Arrangements H02H 1/0007 (20130101) H02H 7/122 (20130101) H02H 7/125 (20130101) H02H 7/1213 (20130101) Original (OR) Class Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 1/0009 (20210501) H02M 1/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11706127 | Michael et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VMware, Inc. (Palo Alto, California) |
| ASSIGNEE(S) | VMWARE, INC. (Palo Alto, California) |
| INVENTOR(S) | Nithin Michael (San Francisco, California); Ao Tang (San Francisco, California); Victor de Souza Lima e Silva (San Francisco, California); Thiago Sousa Santos (San Francisco, California); Ning Wu (San Francisco, California); Archit Baweja (San Francisco, California); Ki Suh Lee (San Francisco, California); Yao Wang (San Francisco, California); Andrey Gushchin (San Francisco, California); Sakethnath Are (San Francisco, California) |
| ABSTRACT | A method comprising instantiating virtual routers (VRs) at each of a set of nodes that form a network. Each VR is coupled to the network and to a tenant of the node. The network comprises virtual links in an overlay network provisioned over an underlay network including servers of a public network. The method comprises configuring at least one VR to include a feedback control system comprising at least one objective function that characterizes the network. The method comprises configuring the VR to receive link state data of a set of virtual links of the virtual links, and control routing of a tenant traffic flow of each tenant according to a best route of the network determined by the at least one objective function using the link state data. |
| FILED | Monday, September 13, 2021 |
| APPL NO | 17/474034 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0864 (20130101) H04L 43/0876 (20130101) H04L 45/22 (20130101) Original (OR) Class H04L 45/24 (20130101) H04L 45/745 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11700798 | Pan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wei Pan (Vancouver, Washington) |
| ASSIGNEE(S) | DWP Energy Solutions LLC (Vancouver, Washington) |
| INVENTOR(S) | Wei Pan (Vancouver, Washington) |
| ABSTRACT | A translucent solar module assembly for integration with a greenhouse having a frame with a plurality of roof supports includes a pair of brackets attachable to each of the plurality of roof supports, a bi-facial solar panel attachable to the pair of brackets, and a pair of reflector rails attachable to each of the plurality of roof supports. A dichroic reflector is attachable to the pair of reflector rails. |
| FILED | Friday, June 05, 2020 |
| APPL NO | 16/893631 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 9/14 (20130101) A01G 9/243 (20130101) Original (OR) Class Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 7/22 (20130101) F21V 9/04 (20130101) F21V 9/20 (20180201) Solar Heat Collectors; Solar Heat Systems F24S 25/61 (20180501) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/0814 (20220101) Optical Elements, Systems, or Apparatus G02B 6/29361 (20130101) G02B 27/141 (20130101) G02B 2027/0114 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 33/12 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0475 (20141201) H01L 31/0488 (20130101) H01L 31/0504 (20130101) H01L 31/0549 (20141201) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/23 (20141201) H02S 30/10 (20141201) H02S 40/22 (20141201) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 10/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701077 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Xianbo Shi (Naperville, Illinois); Zhi Qiao (Darien, Illinois); Michael J. Wojcik (Orland Park, Illinois); Lahsen Assoufid (Chicago, Illinois) |
| ABSTRACT | Phase contrast and dark-field X-ray imaging enable imaging of objects that absorb or reflect very little X-ray light. Disclosed is a method and systems for performing coded-mask-based multi-contrast imaging (CMMI). The method includes providing radiation to a coded mask that has a known phase and absorption profile according to a pre-determined pattern. The radiation is then impingent upon a sample, and the radiation is detected to perform phase-reconstruction and image processing. The method and associated systems allow for the use of maximum-likelihood and machine learning methods for reconstruction images of the sample from the detected radiation. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/185387 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/40 (20130101) A61B 6/484 (20130101) A61B 6/584 (20130101) A61B 6/4035 (20130101) A61B 6/4085 (20130101) A61B 6/4291 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) G01N 23/041 (20180201) Measurement of Nuclear or X-radiation G01T 1/295 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/02 (20130101) G21K 1/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11701827 | Shusteff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Maxim Shusteff (Livermore, California); Christopher M. Spadaccini (Livermore, California); Nicholas Fang (Livermore, California); Robert Matthew Panas (Livermore, California); Johannes Henriksson (Livermore, California); Brett Kelly (Livermore, California); Allison E. Browar (Livermore, California) |
| ABSTRACT | A multi-beam volumetric resin curing system and method for whole-volume additive manufacturing of an object includes a bath containing a photosensitive resin, a light source for producing a light beam, and a spatial light modulator which produces a phase- or intensity-modulated light beam by impressing a phase profile or intensity profile of an image onto a light beam received from the light source. The system and method also include projection optics which then produces multiple sub-image beams from the modulated light beam which are projected to intersect each other in the photosensitive resin to cure select volumetric regions of the resin in a whole-volume three-dimensional pattern representing the object. |
| FILED | Wednesday, December 23, 2020 |
| APPL NO | 17/133244 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) B29C 64/264 (20170801) B29C 64/268 (20170801) B29C 64/282 (20170801) Original (OR) Class B29C 64/286 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/2205 (20130101) G03H 1/2294 (20130101) G03H 2001/0094 (20130101) G03H 2001/221 (20130101) G03H 2001/0491 (20130101) G03H 2001/2207 (20130101) G03H 2210/30 (20130101) G03H 2210/33 (20130101) G03H 2225/22 (20130101) G03H 2225/32 (20130101) G03H 2225/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702059 | Gosala et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | CUMMINS INC. (Columbus, Indiana) |
| INVENTOR(S) | Dheeraj B. Gosala (Columbus, Indiana); Carlos A. Lana (Columbus, Indiana) |
| ABSTRACT | At least some embodiments of the present disclosure are directed to systems and methods of online power management for hybrid powertrains. In some embodiments, the hybrid powertrain control system is configured to conduct a brake-thermal-efficiency (BTE) estimation procedure when the powertrain is in operation by operating the hybrid powertrain at a plurality of speeds for a plurality of designated power levels and select certain BTE operating conditions to update the power management. |
| FILED | Wednesday, July 22, 2020 |
| APPL NO | 16/935346 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 20/00 (20130101) Original (OR) Class B60W 2510/18 (20130101) B60W 2510/244 (20130101) B60W 2510/0657 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702465 | Lillo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Antonietta Maria Lillo (Los Alamos, New Mexico); Nileena Velappan (Los Alamos, New Mexico); Armand Earl Ko Dichosa (Los Alamos, New Mexico); Stosh Anthony Kozimor (Los Alamos, New Mexico); Laura Margaret Lilley (Los Alamos, New Mexico) |
| ABSTRACT | Monoclonal antibodies that specifically bind the F1 antigen of Yersinia pestis with high affinity are described. Use of the monoclonal antibodies for the detection of Y. pestis infection and the diagnosis of plague are also described. Immunoconjugates of the monoclonal antibodies and a radionuclide can also be used for the treatment of a Y. pestis infection. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/033516 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/1009 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) Peptides C07K 16/1228 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56916 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702486 | Laskowski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 3M Innovative Properties Company (St. Paul, Minnesota); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | 3M Innovative Properties Company (St. Paul, Minnesota); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Carl A. Laskowski (Minneapolis, Minnesota); Michael A. Yandrasits (Hastings, Minnesota); Timothy M. Gillard (St. Paul, Minnesota); Zbyslaw R. Owczarczyk (Littleton, Colorado); Marina M. Kaplun (Woodbury, Minnesota) |
| ABSTRACT | Described herein are cationic polymers having a plurality of quaternary amino groups, methods of making such polymers, and uses of such polymers as ion exchange membranes in electrochemical devices. |
| FILED | Monday, March 11, 2019 |
| APPL NO | 16/980312 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/04 (20130101) C08F 8/32 (20130101) Original (OR) Class C08F 8/44 (20130101) C08F 236/06 (20130101) C08F 297/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/50 (20130101) Compositions of Macromolecular Compounds C08L 53/025 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702551 | Zalich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Michael A. Zalich (Wexford, Pennsylvania); Paul H. Berdahl (Walnut Creek, California); Stuart D. Hellring (Pittsburgh, Pennsylvania) |
| ABSTRACT | A coating composition includes: (i) a film-forming resin; (ii) an infrared reflective pigment; and (iii) an infrared fluorescent pigment or dye different from the infrared reflective pigment. A multi-layer coating including the coating composition, and a substrate at least partially coated with the coating composition is also disclosed. A method of detecting an article at least partially coated with the coating composition is also disclosed. |
| FILED | Thursday, May 26, 2022 |
| APPL NO | 17/825623 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 5/063 (20130101) B05D 7/52 (20130101) B05D 7/546 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/013 (20180101) C08K 5/0041 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/004 (20130101) Original (OR) Class C09D 5/22 (20130101) C09D 7/62 (20180101) C09D 127/16 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/06 (20130101) C09K 11/55 (20130101) C09K 11/58 (20130101) C09K 11/59 (20130101) C09K 11/592 (20130101) C09K 11/685 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702604 | Patel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nikhil Manubhai Patel (Grand Forks, North Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nikhil Manubhai Patel (Grand Forks, North Dakota) |
| ABSTRACT | gasifier and a gasification process provides a long, uniform temperature zone in the gasifier, regardless of the particle size, chemical composition, and moisture content of the fuel by sandwiching a reduction zones between two oxidation zones. The gasifier and gasification process produces a char that is more energy-dense and almost devoid of moisture, affording an additional (char) oxidation zone with a temperature that is higher than a first oxidation zone which is closer to an evaporation and devolatilization zone. As such, the additional (char) oxidation zone contributes to augmenting the reduction zone temperature, providing a favorable dual impact in improving syngas composition and near-complete conversion of the tar. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 17/570448 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/08 (20130101) Original (OR) Class C10J 3/22 (20130101) C10J 3/26 (20130101) C10J 3/723 (20130101) C10J 2300/092 (20130101) C10J 2300/093 (20130101) C10J 2300/0946 (20130101) C10J 2300/0956 (20130101) C10J 2300/0959 (20130101) C10J 2300/0976 (20130101) C10J 2300/1246 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 1/024 (20130101) C10K 1/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703027 | Bacelli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Giorgio Bacelli (Albuquerque, New Mexico); David G. Wilson (Tijeras, New Mexico); Dominic Forbush (Billings, Montana); Steven J. Spencer (Albuquerque, New Mexico); Ryan G. Coe (Taos, New Mexico) |
| ABSTRACT | Systems and methods for a WEC controller that uses a self-tuning proportional-integral control law prescribing motor torques to maximize electrical power generation and automatically tune the controller to maximize power absorption. In an embodiment, the controller may be part of any resonant WEC system. The control law relies upon an identified model of device intrinsic impedance to generate a frequency-domain estimate of the wave-induced excitation force and measurements of device velocities. The control law was tested in irregular sea-states that evolved over hours (a rapid, but realistic time-scale) and that changed instantly (an unrealistic scenario to evaluate controller response). |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/866083 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Machines or Engines for Liquids F03B 13/14 (20130101) Original (OR) Class F03B 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703404 | McKay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | John Keith McKay (Fort Collins, Colorado); Caleb Andrew Alvarado (Fort Collins, Colorado); Guy R. Babbitt (Fort Collins, Colorado); Kyle Joseph Palmiscno (Loveland, Colorado); Christopher Wayne Turner (Windsor, Colorado); Bryce Conrad Whitehill (Fort Collins, Colorado) |
| ABSTRACT | This invention comprises a device for measuring root pulling force (RPF) in a plant. The RPF device comprises a plant grasping mechanism, as well as a force measurement sensor. In certain embodiments, the device is automatic, so that the “hand of man” is not required to exert force on the plant while the root pulling force of the plant is being measured. Also disclosed is a root pulling force motion mechanism, which brings the RPF device into proximity of a plant to be measured. Further disclosed is a method for measuring root pulling force of a plant. |
| FILED | Wednesday, June 17, 2020 |
| APPL NO | 16/904195 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Harvesting; Mowing A01D 25/042 (20130101) A01D 27/02 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/023 (20130101) B25J 13/085 (20130101) B25J 15/0033 (20130101) B25J 15/0253 (20130101) B25J 19/023 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/0033 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/894 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704153 | Ros-Giralt |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Reservoir Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | Reservoir Labs, Inc. (New York, New York) |
| INVENTOR(S) | Jordi Ros-Giralt (Newport Beach, California) |
| ABSTRACT | A system for storing and extracting elements according to their priority takes into account not only the priorities of the elements but also three additional parameters, namely, a priority resolution pΔ and two priority limits pmin and pmax. By allowing an ordering error if the difference in the priorities of elements are within the priority resolution, an improvement in performance is achieved. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/355339 |
| ART UNIT | 2195 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4881 (20130101) Original (OR) Class G06F 9/5038 (20130101) G06F 16/245 (20190101) G06F 16/9017 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705250 | McCall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); American Ceramic Technology (Poway, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); American Ceramic Technology (Poway, California) |
| INVENTOR(S) | Scott McCall (Livermore, California); Richard Culbertson (Poway, California) |
| ABSTRACT | A magnetic shielding material includes a material comprising manganese bismuth (MnBi) and tungsten (W), where a ratio of MnBi:W is in a range of 50:50 to about 70:30. A radiation shielding product includes a part including manganese bismuth (MnBi) and tungsten (W), and a plurality of layers having a defined thickness in a z-direction, wherein each layer extends along an x-y plane perpendicular to the z-direction. At least some of the plurality of layers form a functional gradient in the z-direction and/or along the x-y plane, and the functional gradient is defined by a first layer comprising a ratio of MnBi:W being less than 100:0 and an nth layer above the first layer comprising a ratio of MnBi:W greater than 0:100. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/112726 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Alloys C22C 27/04 (20130101) C22C 30/00 (20130101) C22C 2202/02 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 1/085 (20130101) Original (OR) Class G21F 1/125 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/055 (20130101) H01F 27/366 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705255 | Klausner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | James F. Klausner (Haslett, Michigan); Renwei Mei (Gainesville, Florida); Ayyoub Mehdizadeh Momen (Knoxville, Tennessee); Kyle Allen (San Ramon, California) |
| ABSTRACT | Disclosed herein is a method comprising disposing a first particle in a reactor; the first particle being a magnetic particle or a particle that can be influenced by a magnetic field, an electric field or a combination of an electrical field and a magnetic field; fluidizing the first particle in the reactor; applying a uniform magnetic field, a uniform electrical field or a combination of a uniform magnetic field and uniform electrical field to the reactor; elevating the temperature of the reactor; and fusing the first particles to form a monolithic solid. |
| FILED | Wednesday, March 24, 2021 |
| APPL NO | 17/210742 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/745 (20130101) B01J 37/0009 (20130101) B01J 37/0221 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/50 (20170801) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/01 (20130101) C04B 35/515 (20130101) C04B 35/515 (20130101) C04B 38/0038 (20130101) C04B 38/0038 (20130101) C04B 38/0038 (20130101) C04B 38/0096 (20130101) C04B 38/0096 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/01 (20130101) Original (OR) Class H01F 1/342 (20130101) H01F 41/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705580 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Xia Cao (Richland, Washington); Ji-Guang Zhang (Richland, Washington); Wu Xu (Richland, Washington) |
| ABSTRACT | Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/537149 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/587 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2300/0042 (20130101) H01M 2300/0051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705755 | Ding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Fei Ding (Littleton, Colorado); Weijia Liu (Littleton, Colorado) |
| ABSTRACT | An example system includes an aggregator configured to receive a service collaboration request and iteratively determine, based on minimum and maximum power values for DERs under its management, an optimized operation schedule. The aggregator may also be configured to iteratively determine, based on the optimized operation schedule, an estimated flexibility range for devices under its management and output an indication thereof. The system may also include a power management unit (PMU) configured to iteratively receive the indication and determine, based on a network model that includes the estimated flexibility range, a reconfiguration plan and an overall optimized operation schedule for the network. The PMU may also be configured to iteratively cause reconfiguration of the network based on the plan. The PMU and aggregator may also be configured to iteratively, at a fast timescale, cause energy resources under their management to modify operation based on the overall optimized operation schedule. |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/188704 |
| ART UNIT | 2119 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/003 (20200101) H02J 3/004 (20200101) H02J 3/381 (20130101) H02J 9/061 (20130101) H02J 9/068 (20200101) H02J 13/00004 (20200101) Original (OR) Class H02J 2203/10 (20200101) H02J 2300/24 (20200101) H02J 2310/58 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705782 | Alahyari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Abbas A. Alahyari (Glastonbury, Connecticut); Kimberly Rae Saviers (Glastonbury, Connecticut); Jagadeesh Kumar Tangudu (South Windsor, Connecticut); Joseph Turney (Amston, Connecticut) |
| ABSTRACT | A stator and a motor including a stator. The stator includes a stator hub, a plurality of stator teeth extending from the stator hub that define a stator slot having a stator slot base, at least one winding disposed in the stator slot, and one or more oscillating heat pipes disposed at least partially in the at least one winding. The at least one winding is held apart from the stator slot base so that a cooling channel is defined between an inner winding portion of the at least one winding and a portion of the one or more oscillating heat pipes is disposed in the channel so cooling fluid can be passed between the stator slot base and the inner winding portion to cool the inner winding portion via at least operation of the one or more oscillating heat pipes. |
| FILED | Thursday, September 23, 2021 |
| APPL NO | 17/482737 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 1/20 (20130101) H02K 3/12 (20130101) H02K 3/24 (20130101) H02K 3/34 (20130101) H02K 3/48 (20130101) H02K 9/20 (20130101) Original (OR) Class H02K 9/225 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11706192 | Akyol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Bora A. Akyol (El Dorado Hills, California); Jereme N. Haack (West Richland, Washington); Thomas E. Carroll (Richland, Washington); Kyle E. Monson (West Richland, Washington); Penny L. McKenzie (Kennewick, Washington); Keith W. Thornhill (Pasco, Washington); Michael E. Mylrea (Alexandria, Virginia) |
| ABSTRACT | A cybersecurity infrastructure command validation system is provided herein for validating asset commands issued within an infrastructure network. The cybersecurity infrastructure command validation system can be integrated into an infrastructure network to monitor and validate infrastructure asset commands in real-time or while the infrastructure network is active. The cybersecurity infrastructure command validation system can receive or intercept commands issued by asset controllers. The cybersecurity infrastructure command validation system can validate the commands based on a command validation model. The command validation model can represent normal operating behavior of the infrastructure network. The cybersecurity infrastructure command validation system can provide valid commands to the intended infrastructure asset, or can reject invalid commands. The cybersecurity infrastructure command validation system can store validation results for use in updating the command validation model. The cybersecurity infrastructure command validation system can flag or otherwise warn the infrastructure network or administrators of invalid commands. |
| FILED | Wednesday, October 16, 2019 |
| APPL NO | 16/655071 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 9/02 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/0209 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11700860 | Sarker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Wahington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Majher I. Sarker (Hatfield, Pennsylvania); Wilbert Long, III (Philadelphia, Pennsylvania); Cheng Kung Liu (Maple Glen, Pennsylvania) |
| ABSTRACT | Compositions and methods for cleaning and decontaminating animal carcasses are disclosed. The compositions comprise a mud ball remover having a thioglycolate salt and a base and an antimicrobial agent effective to remove mud balls and reduce microbial contamination of a hide surface at ambient temperatures. The methods comprise cleaning and decontaminating an animal carcass by applying the disclosed compositions onto the surface of the animal carcass to soften and loosen foreign debris attached to the carcass followed by mechanically removing the foreign debris while preserving the integrity and quality of the hide byproduct and resulting leather articles. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 16/580586 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/66 (20130101) Slaughtering A22B 5/0082 (20130101) Original (OR) Class Detergent Compositions; Use of Single Substances as Detergents; Soap or Soap-making; Resin Soaps; Recovery of Glycerol C11D 1/04 (20130101) C11D 3/044 (20130101) C11D 3/48 (20130101) C11D 3/323 (20130101) C11D 11/0011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702374 | Bakshi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| ASSIGNEE(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| INVENTOR(S) | Santanu Bakshi (Ames, Iowa); Robert C. Brown (Ames, Iowa); Ryan G. Smith (Ames, Iowa) |
| ABSTRACT | The present application relates to an iron impregnated biochar and its use as a fertilizer. The iron impregnated biochar of the present application has a ratio of iron (III) to iron (II) ranging from 5:1 to 10:1. The biochar may be produced by a method including treating the biomass with an iron (II) ion solution, pyrolyzing the iron (II)-treated biomass in an oxidative environment and recovering the biochar product from the pyrolyzed iron (II)-treated biomass. |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/336804 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Inorganic Fertilisers Not Covered by Subclasses C05B, C05C; Fertilisers Producing Carbon Dioxide C05D 9/00 (20130101) Original (OR) Class Mixtures of Fertilisers Covered Individually by Different Subclasses of Class C05; Mixtures of One or More Fertilisers With Materials Not Having a Specific Fertilising Activity, e.g Pesticides, Soil-conditioners, Wetting Agents; Fertilisers Characterised by Their Form C05G 3/80 (20200201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11702667 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Yinong Yang (State College, Pennsylvania); Kabin Xie (Wuhan, China PRC) |
| ABSTRACT | The invention includes materials and methods to generate numerous small RNAs from one polynucleotide construct (synthetic gene) to facilitate RNA-guided multiplex genome editing, modification, inhibition of expression and other RNA-based technologies. The synthetic gene/polynucleotide construct encodes polycistronic RNA components separated by tRNAs, and preferably also includes regulatory components such as a promoter or terminator to form an expression cassette. Once transcribed in a cell, the transcript is processed by the cell to multiple RNA molecules by the endogenous tRNA processing system. The system can be sued for any RNA based gene manipulation method including RNA-mediated genome editing, artificial microRNA mediated gene silencing, small RNA mediated genetic manipulation, double-stranded RNA mediated gene silencing, antisense mechanisms and the like. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 16/386903 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/8213 (20130101) Original (OR) Class C12N 15/8216 (20130101) C12N 15/8218 (20130101) C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2310/51 (20130101) C12N 2330/31 (20130101) C12N 2330/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11701296 | Oaks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Tristan Oaks (Arlington, Virginia); Wesley Russell (Washington, District of Columbia); Sadie Simons (Ware, Massachusetts); Breanna Wood (Milton, Florida); Michael Plumley (Groton, Connecticut); Ronald Adrezin (East Lyme, Connecticut) |
| ABSTRACT | A method for cardiopulmonary resuscitation (CPR) includes supplying an inflation gas at an operative pressure to an inflation actuated soft gripper device to change form from an undeployed state to a deployed grip state that accommodates and grips a human torso. The inflation actuated soft gripper device includes a first inflatable gripper arm having a first distal end and a second inflatable gripper arm having a second distal end. The first distal end and the second distal end approach one another from the undeployed state to the deployed grip state. The first and second distal ends are spaced apart from one another further in the undeployed state than in the deployed grip state. An actuator power and a CPR control signal are delivered to a CPR pressure application device to cyclically extend and retract a pressure applicator along an axis in alignment with a sternum of the human torso. |
| FILED | Thursday, January 12, 2023 |
| APPL NO | 18/096124 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 31/004 (20130101) A61H 31/006 (20130101) Original (OR) Class A61H 2201/0103 (20130101) A61H 2201/0107 (20130101) A61H 2201/149 (20130101) A61H 2201/0157 (20130101) A61H 2201/1215 (20130101) A61H 2201/1621 (20130101) A61H 2201/1647 (20130101) A61H 2201/1664 (20130101) A61H 2201/5015 (20130101) A61H 2201/5025 (20130101) A61H 2201/5043 (20130101) A61H 2201/5097 (20130101) A61H 2205/084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703471 | Gregory et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rhode Island Board of Trustees (Kingston, Rhode Island) |
| ASSIGNEE(S) | University of Rhode Island Board of Trustees (Kingston, Rhode Island) |
| INVENTOR(S) | Otto J. Gregory (Narragansett, Rhode Island); Peter Ricci, III (West Warwick, Rhode Island); Andrew Rossi (Portsmouth, Rhode Island) |
| ABSTRACT | Methods and apparatuses for highly sensitive detection of analytes using redox reactions. A library of heat reactions of analytes of interest with a variety of catalysts at a variety of temperatures is prepared. An array of sensors with low thermal mass heating elements is prepared, depositing the same or different catalysts, such as metal oxide catalysts that have multiple oxidation states, on each heating element. The low thermal mass heating elements are preferably not in thermal contact with a substrate, or a low mass substrate is used. The array is exposed to a sample at various temperatures. The sign and magnitude of the heat effect of the redox reaction of compounds in the sample or their decomposition products with each catalyst is measured and compared with the library. The catalysts and temperatures are chosen so that the desired analytes have a unique pattern of heat effect signs and magnitudes when reacted with those catalysts at those temperatures. The resulting detector is highly selective and sensitive to the analytes of interest. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/724068 |
| ART UNIT | 1796 — Optics |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/52 (20130101) B01J 35/023 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/34 (20130101) G01N 25/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11706078 | Clark et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Two Six Labs, LLC (Arlington, Virginia) |
| ASSIGNEE(S) | Two Six Labs, LLC (Arlington, Virginia) |
| INVENTOR(S) | Chae A. Clark (Arlington, Virginia); Robert P. Gove, Jr. (Reston, Virginia); Violet Lingenfelter (Arlington, Virginia); Anthony Wong (Arlington, Virginia) |
| ABSTRACT | A network disruption detection engine gathers and stores network routing path update messages that routinely modify routing tables used by internet routers for transporting message traffic between a source and a destination. Routing path messages continually maintain a network transport infrastructure both for intranets used for particular entities such as corporations, and internet traffic between arbitrary source and destination nodes. Major disruptions or outages typically result in an increase in routing path messages, typically focused on a particular set, region or network entity where the disruption occurred, as other routing entities seek to avoid the troubled region. Analysis of this sudden activity of routing messages and extracting message content about the network region they seek to avoid allows identification and queries of a widespread network outage. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/207985 |
| ART UNIT | 2454 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/06 (20130101) Original (OR) Class H04L 41/12 (20130101) H04L 41/0677 (20130101) H04L 43/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11702662 | Jacobson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gen9, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Gen9, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Joseph Jacobson (Newton, Massachusetts); Daniel Schindler (Newton Upper Falls, Massachusetts); Scott S. Lawton (Bedford, Massachusetts) |
| ABSTRACT | Aspects of the invention relate to methods, compositions and algorithms for designing and producing a target nucleic acid. The method can include: (1) providing a plurality of blunt-end double-stranded nucleic acid fragments having a restriction enzyme recognition sequence at both ends thereof; (2) producing via enzymatic digestion a plurality of cohesive-end double-stranded nucleic acid fragments each having two different and non-complementary overhangs; (3) ligating the plurality of cohesive-end double-stranded nucleic acid fragments with a ligase; and (4) forming a linear arrangement of the plurality of cohesive-end double-stranded nucleic acid fragments, wherein the unique arrangement comprises the target nucleic acid. In certain embodiments, the plurality of blunt-end double-stranded nucleic acid fragments can be provided by: releasing a plurality of oligonucleotides synthesized on a solid support; and synthesizing complementary strands of the plurality of oligonucleotides using a polymerase based reaction. |
| FILED | Monday, July 12, 2021 |
| APPL NO | 17/373324 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/10 (20130101) C12N 15/66 (20130101) Original (OR) Class C12N 15/1027 (20130101) C12N 15/1027 (20130101) C12N 15/1031 (20130101) C12N 15/1089 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2521/301 (20130101) C12Q 2521/301 (20130101) C12Q 2521/301 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) C12Q 2521/501 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) G16B 30/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11705373 | Moody et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Michael J. Moody (Chicago, Illinois); Lincoln J. Lauhon (Chicago, Illinois); Ju Ying Shang (Romeoville, Illinois) |
| ABSTRACT | A system and method for performing in-situ measurements of semiconductor devices during chemical vapor deposition (CVD) includes disposing a chip carrier within a sealed chamber of a reactor for carrying out in-situ monitoring of partially fabricated semiconductor devices. The chip carrier includes a plurality of metallized bonding pads disposed along both peripheral edges on a same surface of the base for making electrical connections to metallized pads or contacts on the semiconductor device through bonding wires. Each of the plurality of metallized bonding pads disposed along both peripheral edges is electrically connected to each other as a pair through electrically connecting to a corresponding pair of ports which are disposed along both peripheral edges of the chip carrier. In-situ monitoring of the partially fabricated semiconductor device is performed through connecting the plurality of ports on the chip carrier to an external source-measure unit through a connector and wire harness. |
| FILED | Wednesday, March 10, 2021 |
| APPL NO | 17/197654 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/52 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/2621 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/67253 (20130101) H01L 22/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11701046 | Sridhar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Srinivas Sridhar (Newton, Massachusetts); Craig Versek (Cranston, Rhode Island); Peter Bex (Concord, Massachusetts) |
| ABSTRACT | A portable wireless neuromonitoring device can be used to diagnose and/or treat conditions of the brain and vision system. The device includes a sensor unit mountable on the head of a human subject and capable of recording signals from the brain in EEG and/or EFEG (electric field encephalography) mode, and the device can be used for simultaneous stimulus display and recording with latency of less than 1 millisecond. The device also includes electrodes that allow rapid set-up and measurement with low impedance contact with the scalp. The device can also be used in conjunction with virtual reality or alternate reality environments. |
| FILED | Thursday, November 02, 2017 |
| APPL NO | 16/347049 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/10 (20130101) A61B 5/162 (20130101) A61B 5/291 (20210101) Original (OR) Class A61B 5/378 (20210101) A61B 5/742 (20130101) A61B 5/4082 (20130101) A61B 5/4088 (20130101) A61B 5/6803 (20130101) A61B 5/6831 (20130101) A61B 5/7264 (20130101) A61B 2562/14 (20130101) A61B 2562/0209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704582 | Jain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VigNet Incorporated (Fairfax, Virginia) |
| ASSIGNEE(S) | VigNet Incorporated (Fairfax, Virginia) |
| INVENTOR(S) | Praduman Jain (Fairfax, Virginia); Dave Klein (Oakton, Virginia); Josh Schilling (Salem, Oregon) |
| ABSTRACT | Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for using machine learning to generate precision predictions of readiness. In some implementations, a database is accessed to obtain status data that indicates activities or attributes of a subject. A set of feature scores is derived from the status data for the subject, the set of feature scores including values indicative of attributes or activities of the subject. The set of feature scores to one or more models that have been configured to predict readiness of subjects to satisfy one or more readiness criteria. The one or models can be models configured using machine learning training. Based on processing performed using the one or more machine learning models and the set of feature scores, a prediction regarding the subject's ability to achieve readiness to satisfy the one or more readiness criteria is generated. |
| FILED | Wednesday, October 06, 2021 |
| APPL NO | 17/494879 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 24/00 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Original (OR) Class G06N 20/00 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11703565 | Schlehuber |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Steven R. Schlehuber (Marlborough, Massachusetts) |
| ABSTRACT | A tracking method and system includes receiving a primary radar report after establishment of a real track of the aircraft, determining a false track slant range associated with the aircraft based on an effective altitude of the aircraft above a ground or water surface and an aircraft slant range defined between the radar arranged on the ground surface and the aircraft, determining a capture area based on the false track slant range and an azimuth of the aircraft, and determining whether the primary radar report is a false report by comparing a position of the aircraft determined from the primary radar report to the capture area. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 16/834768 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/414 (20130101) Original (OR) Class G01S 13/91 (20130101) G01S 13/723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 11701642 | Al-Abed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government, as represented by the Administrator of the U.S. EPA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government, as represented by the Administrator of the U.S. EPA, Waashington DC (Washington, District of Columbia) |
| INVENTOR(S) | Souhail Al-Abed (Cincinnati, Ohio); John McKernan (Cincinnati, Ohio); Slawomir Lomnicki (Baton Rouge, Louisiana) |
| ABSTRACT | Catalyst materials comprising iron and palladium are described. Also described are methods for preparing such materials. In addition, methods for remediating materials such as sediments and groundwater using the catalyst materials are described. |
| FILED | Tuesday, February 18, 2020 |
| APPL NO | 16/793538 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/8906 (20130101) Original (OR) Class B01J 35/1061 (20130101) B01J 37/14 (20130101) B01J 37/18 (20130101) B01J 37/0203 (20130101) B01J 37/0213 (20130101) Reclamation of Contaminated Soil B09C 1/002 (20130101) B09C 1/08 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/725 (20130101) C02F 2101/36 (20130101) C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11703544 | Bolotin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Gary S. Bolotin (Pasadena, California); Don J. Hunter (LaVerne, California); Malcolm L. Lias (Pasadena, California); Ben Cheng (Pasadena, California); John J. Waters (Pasadena, California); Sunant Katanyoutanant (Monterey Park, California) |
| ABSTRACT | Current sensing devices that are capable of surviving harsh ambient environment of ocean worlds, such as Jupiter and Saturn moons are disclosed. The described devices can meet 300 Krad radiation requirements and can survive at cold temperatures down to −184° C. Exemplary implementations of the constituent circuits of the devices are presented. A scheduling algorithm to perform various measurement by the disclosed current sensing devices is also described. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/339502 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/66 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 19/22 (20130101) G01R 31/34 (20130101) Original (OR) Class Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 29/60 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 11703257 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Zunfeng Liu (Tianjin, China PRC); Run Wang (Tianjin, China PRC); Jiuke Mu (Plano, Texas); Zhong Wang (Dallas, Texas); Shaoli Fang (Richardson, Texas); Marcio Dias Lima (Richardson, Texas); Ali E. Aliev (Plano, Texas); Na Li (Milwaukee, Wisconsin); Carter S. Haines (Murphy, Texas); Ray H. Baughman (Dallas, Texas) |
| ABSTRACT | Cooling by a twist-untwist process, by a stretch-release process for twisted, coiled, or supercoiled yarns or fibers, and methods and systems thereof. High mechanocaloric cooling results from release of inserted twist or from stretch release for twisted, coiled, or supercoiled fibers, including natural rubber fibers, NiTi wires, and polyethylene fishing line. Twist utilization can increase cooling and cooling efficiencies. A cooler using twist insertion and release can be shorter and smaller in volume than a cooler that requires a large elastomeric elongation. The cooler system can be utilized in mechanochromic textiles and remotely readable tensile and torsional sensors. |
| FILED | Tuesday, September 29, 2020 |
| APPL NO | 17/036018 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/44 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/06 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/0612 (20210801) F03G 7/0615 (20210801) F03G 7/06113 (20210801) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/00 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 10/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2925 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11703014 | Shealy |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | James Shealy (Cincinnati, Ohio) |
| ABSTRACT | An apparatus for sealing such a gap may be a plunger seal which may include a flap arm comprising resilient sheets and a wall arm comprising resilient sheets. A proximal end portion of the flap arm may include a closeout seal coupled to the flap. A proximal end portion of the wall arm may include a plunger having a geometry corresponding to that of the closeout seal so the plunger may be matingly received by the closeout seal. When positioned in a gap, the plunger seal may exert a force to urge the flap arm towards the flap and to urge the wall arm and resilient sheet towards the structure to seal the gap. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 17/362391 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/005 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Jet-propulsion Plants F02K 1/805 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/55 (20130101) F05D 2240/59 (20130101) Pistons; Cylinders; Sealings F16J 15/0887 (20130101) F16J 15/0893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11703549 | Bagga et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sunny Bagga (Corona, California); Brian J. Cadwell (Pasadena, California); Shaun Mark Goodwin (East New Market, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Sunny Bagga (Corona, California); Brian J. Cadwell (Pasadena, California); Shaun Mark Goodwin (East New Market, Maryland) |
| ABSTRACT | A ground fault detection circuit can include a band-pass filter that can have a first node and a second node that can be coupled to an earth ground. The first node can be coupled to a local ground of an automatic test equipment (ATE) system for an electrical device that can be coupled via at least one wire to the ATE. The band-pass filter can be configured to pass and amplify a test current signal established at the first node in response to a coupling of one of a conductor of the at least one wire carrying the test current signal to the local ground, and a conductive element of the electrical device carrying the test current signal to the local ground. A fault alert signal can be provided to provide an indication of ground fault based on a comparison of the amplified test current signal. |
| FILED | Thursday, April 30, 2020 |
| APPL NO | 16/863308 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/52 (20200101) Original (OR) Class G01R 31/083 (20130101) G01R 31/2834 (20130101) G01R 31/31905 (20130101) G01R 31/31932 (20130101) Emergency Protective Circuit Arrangements H02H 3/16 (20130101) H02H 3/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11704227 | Jackson, II et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Gary L. Jackson, II (Laurel, Maryland); Sterling E. Vinson, II (Columbia, Maryland) |
| ABSTRACT | A test environment apparatus having processing circuitry is provided for testing an embedded system-under-test. The processing circuitry may be configured to implement the system-under-test for interaction with external test participants via messaging and control operation of an inner agent and an outer agent. The inner agent may be implemented within a virtual machine that is also implementing the system-under-test and the outer agent may be implemented external to the virtual machine implementing the system-under-test. The inner agent and the outer agent may be controlled to operate collaboratively to trigger captures of snapshots that store current states of the system-under-test at respective times and trigger a rollback of the system-under-test based on a timestamp of a delayed message using a snapshot for a selected time that provides a state of the system-under-test prior to the timestamp to permit subsequent delivery of the delayed message with the system-under-test in a rollback state. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/358134 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 11/1469 (20130101) G06F 11/3664 (20130101) Original (OR) Class G06F 2009/45591 (20130101) G06F 2201/84 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 18, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230718.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page