FedInvent™ Patents
Patent Details for Tuesday, September 26, 2023
This page was updated on Wednesday, September 27, 2023 at 05:53 AM GMT
Department of Health and Human Services (HHS)
| US 11766172 | Rege et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vasoptic Medical Inc. (Baltimore, Maryland) |
| ASSIGNEE(S) | Vasoptic Medical Inc. (Columbia, Maryland) |
| INVENTOR(S) | Abhishek Rege (Baltimore, Maryland); M. Jason Brooke (University Park, Maryland) |
| ABSTRACT | Imaging various regions of the eye is important for both clinical diagnostic and treatment purposes as well as for scientific research. Diagnosis of a number of clinical conditions relies on imaging of the various tissues of the eye. The subject technology describes a method and apparatus for imaging of the back and/or front of the eye using multiple illumination modalities, which permits the collection of one or more of reflectance, spectroscopic, fluorescence, and laser speckle contrast images. |
| FILED | Friday, July 24, 2020 |
| APPL NO | 16/938492 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/12 (20130101) A61B 3/14 (20130101) Original (OR) Class A61B 3/18 (20130101) A61B 3/0025 (20130101) A61B 3/0033 (20130101) A61B 3/0041 (20130101) A61B 3/0075 (20130101) A61B 3/0083 (20130101) A61B 3/0091 (20130101) A61B 3/152 (20130101) A61B 3/1208 (20130101) A61B 3/1233 (20130101) A61B 3/1241 (20130101) A61B 5/0013 (20130101) A61B 5/02007 (20130101) A61B 5/6803 (20130101) A61B 2560/0475 (20130101) Optical Elements, Systems, or Apparatus G02B 27/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766343 | Dillingham |
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| APPLICANT(S) | iFIT Prosthetics, LLC (Pewaukee, Wisconsin) |
| ASSIGNEE(S) | iFIT Prosthetics, LLC (Pewaukee, Wisconsin) |
| INVENTOR(S) | Timothy R. Dillingham (Philadelphia, Pennsylvania) |
| ABSTRACT | An apparatus for adjusting an expandable prosthetic device includes: an elongated main support having a longitudinal axis and a distal end, and being adapted to connect to an outer or inner side of an adjustable socket having a distal end; an adjustable cup adapted to connect to the distal end of the elongated main support and having an expandable base and at least one side adapted to move laterally toward or laterally away from the longitudinal axis of the elongated main support; and at least a portion of a suspension system disposed in the adjustable cup and having a top adapted to connect to the distal end of the adjustable socket and a bottom adapted to slidably connect to the expandable base of the adjustable cup. |
| FILED | Wednesday, January 11, 2023 |
| APPL NO | 18/095715 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/76 (20130101) A61F 2/80 (20130101) Original (OR) Class A61F 2002/509 (20130101) A61F 2002/5026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766403 | Moudgil et al. |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Kamal D. Moudgil (Silver Springs, Maryland); Rakeshchandra R. Meka (Halethorp, Maryland) |
| ABSTRACT | The present invention relates in part to compositions for targeted delivery of an agent and agent delivery systems comprising a novel tissue-targeting peptide ligand (CKPFDRALC) (SEQ ID NO: 1) named ART-2. In certain aspects, the ART-2-coated liposomes encapsulating an agent, such as a therapeutic agent, diagnostic agent, imaging agent, or any combination thereof, were more effective in inhibiting, diagnosing, or imaging a disease or disorder, such as an arthritis progression, than control, despite a comparable safety profile. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 16/825371 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) Original (OR) Class A61K 38/08 (20130101) A61K 47/42 (20130101) A61K 47/64 (20170801) A61K 47/6911 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) Peptides C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766408 | Cheng et al. |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Qiang Cheng (Dallas, Texas); Tuo Wei (Dallas, Texas); Daniel J. Siegwart (Dallas, Texas) |
| ABSTRACT | The present disclosure provides compositions which shown preferential targeting or delivery of a nucleic acid composition to a particular organ. In some embodiments, the composition comprises a steroid or sterol, an ionizable cationic lipid, a phospholipid, a PEG lipid, and a permanently cationic lipid which may be used to deliver a nucleic acid. |
| FILED | Thursday, March 04, 2021 |
| APPL NO | 17/191975 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/553 (20130101) A61K 9/51 (20130101) A61K 9/127 (20130101) A61K 9/1271 (20130101) A61K 9/1272 (20130101) A61K 9/5123 (20130101) Original (OR) Class A61K 31/713 (20130101) A61K 31/7105 (20130101) A61K 38/465 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766423 | Slusher et al. |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER, NATIONAL INSTITUTES OF HEALTH (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barbara Slusher (Kingsville, Maryland); Camilo Rojas (Baltimore, Maryland); Ajit G. Thomas (Baltimore, Maryland); Norman Haughey (Baltimore, Maryland); Marc Ferrer (Potomac, Maryland); Xin Hu (Frederick, Maryland) |
| ABSTRACT | Methods for treating one or more diseases associated with neutral sphingomyelinase 2 (nSMase2) in a subject in need of treatment thereof, the method comprising administering to the subject a therapeutically effective amount of 2,6-dimethoxy-4-(5-phenyl-4-thiophen-2-yl-1H-imidazol-2-yl)-phenol (DPTIP) or a pharmaceutically acceptable salt thereof, are disclosed. |
| FILED | Friday, March 01, 2019 |
| APPL NO | 16/977305 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4178 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766433 | Wipf et al. |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Peter Wipf (Pittsburgh, Pennsylvania); James K. Johnson (Silver Spring, Maryland); Erin M. Skoda (Silver Spring, Maryland); Joel B. Nelson (Pittsburgh, Pennsylvania); Zhou Wang (Pittsburgh, Pennsylvania); Serene Tai (Pittsburgh, Pennsylvania); Keita Takubo (Pittsburgh, Pennsylvania); John Milligan (Philadelphia, Pennsylvania) |
| ABSTRACT | A compound, or a pharmaceutically acceptable salt or ester thereof, according to formula I: R20—(Z)b—(Y)c—(R21)a—(X)d—R22—R23 wherein R20 is aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a thio-containing group, or a seleno-containing group; Z is alkanediyl, substituted alkanediyl, cycloalkanediyl, or substituted cycloalkanediyl; Y is S, O, S(═O), —S(═O)(═O)—, or NR10, wherein R10 is H or alkyl; R21 is alkanediyl, substituted alkanediyl, cycloalkanediyl, substituted cycloalkanediyl, alkadienyl, substituted alkadienyl, cycloalkenediyl, substituted cycloalkenediyl, alkatrienyl, substituted alkatrienyl; X is —C(═O)—, —S(═O)(═O)—, or —N(H)C(═O)—; R22 includes at least one divalent amino radical; R23 is aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a thio-containing group, or a seleno-containing group; a, b, c, and d independently are 0 or 1. |
| FILED | Wednesday, November 04, 2020 |
| APPL NO | 17/089519 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/47 (20130101) A61K 31/58 (20130101) A61K 31/122 (20130101) A61K 31/167 (20130101) A61K 31/401 (20130101) A61K 31/407 (20130101) A61K 31/497 (20130101) A61K 31/504 (20130101) Original (OR) Class A61K 31/4166 (20130101) A61K 31/4439 (20130101) A61K 31/4985 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766440 | Zuo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| ASSIGNEE(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| INVENTOR(S) | Jian Zuo (Omaha, Nebraska); Zhuo Li (Omaha, Nebraska) |
| ABSTRACT | In one aspect, use of compounds as active agents to treat a hearing impairment and to prevent a hearing impairment, and methods of treating and/or preventing hearing impairments or disorders using the compositions are disclosed. Momelotinib and Fedratinib exhibit excellent protection against antibiotic-induced hearing loss in zebrafish and mice when administered prophylactically. In one aspect, Momelotinib or Fedratinib can be used as a therapy for the treatment and/or prevention of hearing loss. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Monday, March 06, 2023 |
| APPL NO | 18/117852 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5377 (20130101) Original (OR) Class A61K 31/7036 (20130101) A61K 33/243 (20190101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766448 | Wilson et al. |
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| APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | James M. Wilson (Philadelphia, Pennsylvania); Christie L. Bell (Boston, Massachusetts); Luc H. Vandenberghe (Weston, Massachusetts) |
| ABSTRACT | A method of altering the targeting and/or cellular uptake efficiency of an adeno-associated virus (AAV) viral vector having a capsid containing an AAV9 cell surface binding domain is described. The method involves modifying a clade F cell surface receptor which comprises a glycan having a terminal sialic acid residue and a penultimate β-galactose residue. The modification may involve retargeting the vector by temporarily functionally ablate AAV9 binding in a subset of cells, thereby redirecting the vector to another subset of cells. Alternatively, the modification may involve increasing cellular update efficiency by treating the cells with a neuraminidase to expose cell surface β-galactose. Also provided are compositions containing the AAV9 vector and a neuraminidase. Also provided is a method for purifying AAV9 using β-galactose linked to solid support. Also provided are mutant vectors which have been modified to alter their targeting specificity, including mutant AAV9 in which the galactose binding domain is mutated and AAV in which an AAV9 galactose binding domain is engineered. |
| FILED | Wednesday, January 27, 2021 |
| APPL NO | 17/159735 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/685 (20130101) A61K 31/7088 (20130101) Original (OR) Class A61K 38/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14043 (20130101) C12N 2750/14045 (20130101) C12N 2810/6027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11766461 — Compositions and methods for nucleic acid expression and protein secretion in Bacteroides
| US 11766461 | Sonnenburg et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Stanford Junior (California, Canada) |
| INVENTOR(S) | Justin L. Sonnenburg (Redwood City, California); Weston R. Whitaker (Daly City, California); Elizabeth Stanley (Portola Valley, California) |
| ABSTRACT | Provided are nucleic acids that include a promoter, where the promoter is operable in a Bacteroides cell and is operably linked to a heterologous nucleotide sequence of interest. Also provided are nucleic acids that include a promoter (operable in a prokaryotic cell such as a Bacteroides cell) operably linked to a sequence encoding a synthetic ribosomal binding site (RBS). Also provided are fusion proteins (and nucleic acids encoding them) in which a secreted Bacteroides polypeptide is fused to a heterologous polypeptide of interest. Also provided are prokaryotic cells (e.g., E. coli, a Bacteroides cell, and the like) that include one more nucleic acids such as those described above. Also provided are methods of expression in a prokaryotic cell, methods of detectably labeling a Bacteroides cell in an animal's gut, and methods of delivering a protein to an individual's gut. |
| FILED | Tuesday, April 18, 2017 |
| APPL NO | 16/094694 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 38/00 (20130101) Peptides C07K 14/195 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0069 (20130101) C12N 15/52 (20130101) C12N 15/70 (20130101) C12N 15/74 (20130101) C12N 15/90 (20130101) C12N 2795/00022 (20130101) C12N 2795/10043 (20130101) Enzymes C12Y 113/12005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766467 | Nair |
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| APPLICANT(S) | University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | Sreejayan Nair (Laramie, Wyoming) |
| ABSTRACT | Diabetic wounds have elevated levels of cathepsin K, a protease enzyme, which degrades proteins, such as collagen, causing delayed wound healing. By targeting cathepsin K, diabetic wound healing is ameliorated. Methods and devices for treatment include intradermal injection of odanacatib at or adjacent a wound. Methods and devices for treatment include topical application of pharmacological inhibitors of cathepsin K, for example, in the form of gel, powder, or bandage. Other methods and systems include localized genetic knock out of the cathepsin K gene by topical application of a small interfering RNA (siRNA) or antisense oligonucleotide to aid in wound healing. |
| FILED | Friday, August 28, 2020 |
| APPL NO | 17/006003 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 38/08 (20130101) Original (OR) Class A61K 38/4886 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/44 (20130101) A61L 15/425 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766471 | Spiegelman et al. |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Bruce M. Spiegelman (Waban, Massachusetts); Shingo Kajimura (San Francisco, California) |
| ABSTRACT | The invention provides methods and compositions for inducing brown fat cell differentiation through modulation of both Prdm16 and C/EBPβ activity and/or expression. Also provided are methods for preventing or treating obesity or an obesity related disorder in a subject through stimulation of both Prdm16 and C/EBPβ expression and/or activity. Further provided are methods for identifying compounds that are capable of modulating both Prdm16 and C/EBPβ expression and/or activity. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 16/720142 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/405 (20130101) A61K 31/573 (20130101) A61K 31/4439 (20130101) A61K 38/00 (20130101) A61K 38/28 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/16 (20130101) C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766478 | Wu et al. |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Tzyy-Choou Wu (Stevenson, Maryland); Chien-Fu Hung (Timonium, Maryland) |
| ABSTRACT | Described herein are methods comprising administering to a mammalian subject an effective amount of an annexin chimeric fusion protein, wherein the annexin chimeric fusion protein comprises at least one immunogenic antigen, thereby enhancing the antigen specific immune response relative to administration of the immunogenic antigen alone. Methods and kits for treating or preventing recurrence of hyper proliferating diseases, e.g., cancer, are described. A method may comprise priming a mammal by administering to the mammal an effective amount of a chemotherapeutic agent and boosting the mammal by administering to the mammal an effective amount of an annexin chimeric fusion. |
| FILED | Friday, August 28, 2020 |
| APPL NO | 17/006224 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 33/243 (20190101) A61K 38/1709 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 47/643 (20170801) A61K 47/646 (20170801) A61K 2039/54 (20130101) A61K 2039/545 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/4721 (20130101) C07K 2319/40 (20130101) C07K 2319/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766481 | Flynn et al. |
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| FUNDED BY |
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| APPLICANT(S) | GanNA Bio, Inc. (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | GanNA Bio, Inc. (Cambridge, Massachusetts); The Children's Medical Center (Boston, Massachusetts) |
| INVENTOR(S) | Ryan A. Flynn (Brookline, Massachusetts); Brian Goodman (Boston, Massachusetts); Ciaran Lawlor (Milton, Massachusetts); Namita Bisaria (Somerville, Massachusetts); Richard D. Cummings (Brookline, Massachusetts); Mohui Wei (Boston, Massachusetts); Carolyn R. Bertozzi (Menlo Park, California) |
| ABSTRACT | The present disclosure relates to glycan-modified nucleic acids, including short interfering RNA molecules. The glycan-modified nucleic acids include an oligosaccharide moiety that is bond to the nucleic acid and that contains a multiple antennary complex type N-glycan. The disclosure also relates to pharmaceutical compositions containing such glycan-modified nucleic acids, and methods for making and using such glycan-modified nucleic acids. |
| FILED | Thursday, May 26, 2022 |
| APPL NO | 17/825737 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/61 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766488 | Jaskula-Ranga et al. |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Vinod Jaskula-Ranga (Cambridge, Massachusetts); Donald Zack (Baltimore, Maryland); Derek Welsbie (Baltimore, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides compositions and methods comprising improvements of a CRISPR system (e.g. CRISPR associated (Cas) 9 (CRISPR-Cas9, non-Cas9 CRISPR systems). Such compositions may comprise modifications to the H1 promoter region, addition of 5′UTR modifications, different orthologous sequences of the H1 promoter, novel compact bidirectional promoter sequences with both pol II and pol III activity, addition of Kozak consensus sequences, termination sequences, addition of conditional pol II/pol III bidirectional promoter expression, addition of a donor template sequence for correcting mutations, or combinations thereof. Other aspects of the invention relate to modifications to Cas9 through post-transcriptional cell-cycle regulation fusions, engineered partial target sites such that the nuclease can bind without DNA cleavage, auto-regulation sites, and N-terminal modifications to modulate half-life. |
| FILED | Wednesday, July 05, 2017 |
| APPL NO | 16/315458 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2310/20 (20170501) C12N 2330/51 (20130101) C12N 2710/10344 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766518 | El-Khatib et al. |
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| APPLICANT(S) | BETA BIONICS, INC. (Concord, Massachusetts) |
| ASSIGNEE(S) | BETA BIONICS, INC. (Concord, Massachusetts) |
| INVENTOR(S) | Firas H. El-Khatib (Allston, Massachusetts); Edward R. Damiano (Acton, Massachusetts) |
| ABSTRACT | A blood glucose control system is configured to modify therapy provided to a subject. The system can cause first therapy to be delivered by the blood glucose control system to a subject during a first therapy period. The first therapy can be delivered based at least in part on a first value of a control parameter used by a control algorithm to generate a dose control signal. The system can determine a first effect corresponding at least in part to the first therapy and autonomously generate a second value of the control parameter. The system can cause second therapy to be delivered by the blood glucose control system to the subject during a second therapy period, wherein the second therapy is delivered based at least in part on the second value of the control parameter. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/213929 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 5/14244 (20130101) A61M 2005/1726 (20130101) A61M 2005/14208 (20130101) A61M 2205/16 (20130101) A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/505 (20130101) A61M 2205/3553 (20130101) A61M 2205/3561 (20130101) A61M 2205/3584 (20130101) A61M 2205/3592 (20130101) A61M 2230/201 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 20/17 (20180101) G16H 20/60 (20180101) G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767291 | Kattamuri et al. |
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| FUNDED BY |
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| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Padmanabha Venkatesh Kattamuri (Houston, Texas); Laszlo Kurti (Houston, Texas) |
| ABSTRACT | In one aspect, the present disclosure provides methods of preparing a secondary amine. In some embodiments, the secondary amine comprises two different groups or two identical groups. Also provided herein are compositions for use in the preparation of the secondary amine. |
| FILED | Thursday, May 17, 2018 |
| APPL NO | 16/614272 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 69/36 (20130101) C07C 69/675 (20130101) C07C 227/06 (20130101) C07C 229/04 (20130101) C07C 311/19 (20130101) Original (OR) Class C07C 381/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767301 | Spiegel et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); David Caianiello (Brooklyn, New York) |
| ABSTRACT | The present invention is directed to bi-functional compounds which find use as pharmaceutical agents in the treatment of disease states and/or conditions which are mediated through macrophage migration inhibitory factor (MIF) or immunoglubin G (IgG). The present invention is also directed to pharmaceutical compositions which comprise these bi-functional compounds as well as methods for treating disease states and/or conditions which are mediated through MIF/IgG or where MIF/IgG is a contributing factor to the development and perpetuation of diseases and/or conditions, especially including autoimmune diseases and cancer, among others. The purpose of the present invention is to provide a molecular strategy to lower plasma MIF/IgG level in patients with autoimmune diseases or certain types of cancers. The bi-functional molecule construct is comprised of a MIF/IgG-targeting motif, that is derived from small molecule MIF/IgG ligands, and an ASGPr-targeting motif that binds to hepatocyte asialoglycoprotein receptor (ASGPr). The compounds selectively bind MIF or IgG in plasma and subsequently engage the endo-lysosomal pathway of hepatocytes through ASGPr. As a consequence, MIF/IgG is internalized and degraded by hepatocytes, thus resulting in potential attenuation of corresponding disease symptoms which are modulated through MIF/IgG. |
| FILED | Monday, April 08, 2019 |
| APPL NO | 17/046192 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 249/04 (20130101) Original (OR) Class C07D 413/14 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767302 | Fox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Delaware (Newark, Delaware) |
| ASSIGNEE(S) | UNIVERSITY OF DELAWARE (Newark, Delaware) |
| INVENTOR(S) | Joseph M. Fox (Landenberg, Pennsylvania); William Lambert (Gurnee, Illinois); Yinzhi Fang (Newark, Delaware); Christopher William am Ende (Mystic, Connecticut); Subham Mahapatra (Groton, Connecticut); Yixin Xie (Newark, Delaware); Chuanqi Wang (Newark, Delaware) |
| ABSTRACT | Disclosed herein are mono- and di-substituted tetrazines and methods of their preparation and converting an oxetanyl ester to a thio-substituted tetrazine, which is then converted to a mono-substituted tetrazine, a di-substituted tetrazine, or a vinylether disubstituted tetrazine. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 17/492016 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0298 (20130101) B01J 31/2265 (20130101) B01J 31/2409 (20130101) B01J 2531/824 (20130101) Heterocyclic Compounds C07D 257/08 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 401/14 (20130101) C07D 403/08 (20130101) C07D 405/04 (20130101) C07D 409/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Steroids C07J 43/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767303 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Health Research, Inc. (Menands, New York); Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | HEALTH RESEARCH, INC. (Menands, New York); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Hongmin Li (Tucson, Arizona); Zhong Li (Tucson, Arizona); Jia Zhou (League City, Texas); Jimin Xu (Galveston, Texas); Qing-Yu Zhang (Tucson, Arizona) |
| ABSTRACT | The present disclosure relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof. The present disclosure further relates to methods of inhibiting viral replication including contacting one or more cells that have been infected with a virus with an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein the virus comprises a flavivirus. Also disclosed is a method of treating and/or preventing a flavivirus infection and/or a condition resulting from a flavivirus infection including administering an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof under conditions effective to treat and/or prevent a flavivirus infection and/or a condition resulting from a flavivirus infection. |
| FILED | Friday, July 23, 2021 |
| APPL NO | 17/384051 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Acyclic or Carbocyclic Compounds C07C 233/75 (20130101) Heterocyclic Compounds C07D 211/46 (20130101) C07D 213/75 (20130101) C07D 265/30 (20130101) Original (OR) Class C07D 333/54 (20130101) C07D 409/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767334 | Gurney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tetra Discovery Partners, LLC (Grand Rapids, Michigan) |
| ASSIGNEE(S) | Tetra Discovery Partners, LLC (Grand Rapids, Michigan) |
| INVENTOR(S) | Mark E. Gurney (Grand Rapids, Michigan); Timothy J. Hagen (Lisle, Illinois); Xuesheng Mo (Naperville, Illinois); A. Samuel Vellekoop (Altamont, New York); Donna L. Romero (Chesterfield, Missouri); Robert Campbell (Niskayuna, New York); Joel R. Walker (Schenectady, New York); Lei Zhu (Schenectady, New York) |
| ABSTRACT | The present invention relates to compounds and methods useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators. |
| FILED | Thursday, June 23, 2022 |
| APPL NO | 17/808439 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/53 (20130101) A61K 31/69 (20130101) A61K 31/435 (20130101) A61K 31/496 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/4418 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 213/56 (20130101) C07D 213/72 (20130101) C07D 213/74 (20130101) C07D 221/04 (20130101) C07D 239/26 (20130101) C07D 239/70 (20130101) C07D 251/22 (20130101) C07D 251/30 (20130101) C07D 251/42 (20130101) C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 403/12 (20130101) C07D 405/04 (20130101) C07D 409/04 (20130101) C07D 409/14 (20130101) C07D 413/12 (20130101) C07D 413/14 (20130101) C07D 495/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) C07F 5/027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767346 | Zolotukhin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Sergei Zolotukhin (Gainesville, Florida); Sanford L. Boye (Gainesville, Florida); Shannon E. Boye (Gainesville, Florida); Damien Marsic (Rockville, Maryland); Paul D. Gamlin (Birmingham, Alabama) |
| ABSTRACT | Adeno associated viral (AAV) particles are emerging as a useful vehicle for gene delivery to various organs and tissues, one of them being the retina. Provided here are variant AAV (for example, variant serotype 2 (AAV2)) capsid proteins and variant capsid protein containing particles with enhanced ability to transduce retinal cells. |
| FILED | Tuesday, March 08, 2022 |
| APPL NO | 17/689324 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/1037 (20130101) C12N 2320/32 (20130101) C12N 2750/14011 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767347 | Kong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Leopold Kong (Bethesda, Maryland); Ian A. Wilson (La Jolla, California); Natalia De Val (San Diego, California); Andrew B. Ward (San Diego, California); Dennis Burton (La Jolla, California); Linling He (San Diego, California); Jiang Zhu (San Diego, California) |
| ABSTRACT | The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 17/553070 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 47/64 (20170801) A61K 47/6929 (20170801) A61K 2039/645 (20130101) A61K 2039/5258 (20130101) A61K 2039/6031 (20130101) Peptides C07K 14/005 (20130101) C07K 14/162 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767351 | Kalkum et al. |
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| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Markus Kalkum (Azusa, California); Yoko Fujita-Yamaguchi (Pasadena, California); Karine Bagramyan (North Hollywood, California); Teresa B. Hong (El Monte, California); Sarah Shuck (Orange, California) |
| ABSTRACT | Disclosed herein are a recombinant Streptomyces S27S5 hemagglutinin (SHA), and homologues thereof, and a fusion protein of a fluorescent protein (such as GFP and mCherry1) and SHA or a homologue thereof, which specifically bind to carbohydrates, including oligomeric sugars that terminate in L-rhamnose or D-galactose. The SHA, SHA homologues, and fusion proteins can be used to detect a variety of microorganisms or cancer or tumor antigens. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/394313 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/08 (20130101) Peptides C07K 14/36 (20130101) Original (OR) Class C07K 2319/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/57419 (20130101) G01N 33/57438 (20130101) G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767353 | Sokoloff et al. |
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| FUNDED BY |
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| APPLICANT(S) | Theraly Fibrosis, Inc. (Gaithersburg, Maryland) |
| ASSIGNEE(S) | THERALY FIBROSIS, INC. (Gaithersburg, Maryland) |
| INVENTOR(S) | Alex Sokoloff (Madison, Wisconsin); Viktor Roschke (Bethesda, Maryland); Kang Choon Lee (Seoul, South Korea); Seulki Lee (Ellicott City, Maryland); Yumin Oh (Clarksville, Maryland) |
| ABSTRACT | Fusion polypeptides with modified multimerization domains that provide high expression, solubility, stability, and low immunogenicity to the fusion polypeptides have been developed. TRAIL compositions with the modified multimerization domains show improved physico-chemical and biological properties relative to TRAIL compositions with unmodified multimerization domains. The TRAIL compositions also have lower immunogenicity in the mammalian host when compared to that of TRAIL compositions with unmodified multimerization domains. The TRAIL compositions induce apoptosis of cancer cells and cancer-associated fibroblasts in vivo, reducing tumor size. |
| FILED | Tuesday, April 06, 2021 |
| APPL NO | 17/223283 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 47/60 (20170801) A61K 47/65 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4703 (20130101) Original (OR) Class C07K 14/70575 (20130101) C07K 2319/00 (20130101) C07K 2319/21 (20130101) C07K 2319/73 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767498 | Bobrow et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Johanna Bobrow (Somerville, Massachusetts); Todd Thorsen (Carlisle, Massachusetts); David Walsh (Boston, Massachusetts); Christina Zook (Tewksbury, Massachusetts); Min Jae Song (Laytonsville, Maryland); Marc Ferrer-Alegre (Potomac, Maryland); Sam Michael (Germantown, Maryland); Yen-Ting Tung (Derwood, Maryland); Molly Elizabeth Boutin (Troy, New York) |
| ABSTRACT | An in vitro tissue plate may include a well plate, a fluidic plate disposed on a bottom surface of the well plate, and a media manifold disposed on a bottom surface of the fluidic plate. The well plate may have at least two wells, including a tissue well and a waste well. The fluid plate may include a fluid channel extending between and fluidly connecting the tissue well to the waste well. The media manifold may include a one or more media outlets fluidly connected to the fluid channel. A tissue layer may be deposited in the tissue well. The tissue layer may include human cells such as neurovascular cells. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 16/912941 |
| ART UNIT | 1799 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 2300/0829 (20130101) B01L 2300/0861 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) Original (OR) Class C12M 23/40 (20130101) C12M 25/14 (20130101) C12M 29/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767500 | Murthy |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Shashi K. Murthy (Newton, Massachusetts) |
| ABSTRACT | Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood, and the automated generation of immunotherapeutic products from those dendritic cells, all within a closed system. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease. |
| FILED | Monday, May 23, 2022 |
| APPL NO | 17/664532 |
| ART UNIT | 1799 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 23/28 (20130101) C12M 27/00 (20130101) C12M 29/04 (20130101) C12M 33/00 (20130101) C12M 35/08 (20130101) C12M 41/14 (20130101) C12M 41/48 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0639 (20130101) C12N 2501/22 (20130101) C12N 2501/25 (20130101) C12N 2501/2306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767508 | Ashton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Randolph Scott Ashton (Madison, Wisconsin); Gavin T. Knight (Coral Springs, Florida) |
| ABSTRACT | Described herein are methods, compositions, and kits for directed differentiation of human pluripotent stem cells, neuromesodermal progenitors, and neural stem cells into biomimetic neural tissues comprising one or more rosette structures. Preferably, the methods provided herein direct differentiation of human pluripotent stem cells, neuromesodermal progenitors, and neural stem cells into biomimetic neural tissues comprising a singular neural rosette structure that is comparable to at least a portion of the developing human neural tube. Also described are engineered neural tissue preparations comprising biomimetic neural tissues comprising a singular rosette structure having regional neural progenitor phenotypes. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/044236 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 2501/41 (20130101) C12N 2501/115 (20130101) C12N 2501/119 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/03 (20130101) C12N 2513/00 (20130101) C12N 2533/30 (20130101) C12N 2533/90 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767515 | Wells et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | James M. Wells (Cincinnati, Ohio); Jorge Orlando Munera (Cincinnati, Ohio) |
| ABSTRACT | Disclosed herein are methods for the in vitro differentiation of a precursor cell into definitive endoderm, which may further be differentiated into a human colonic organoid (HCO), via modulation of signaling pathways. Further disclosed are HCOs and methods of using HCOs, which may be used, for example, for the HCOs may be used to determine the efficacy and/or toxicity of a potential therapeutic agent for a disease selected from colitis, colon cancer, polyposis syndromes, and/or irritable bowel syndrome. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 16/461147 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0679 (20130101) Original (OR) Class C12N 2501/11 (20130101) C12N 2501/113 (20130101) C12N 2501/115 (20130101) C12N 2501/117 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2506/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767527 | Khvorova et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Julia Alterman (Worcester, Massachusetts); Faith Conroy (Worcester, Massachusetts); Edith Pfister (Boxborough, Massachusetts); Neil Aronin (Newtonville, Massachusetts); Ken Yamada (Boston, Massachusetts) |
| ABSTRACT | Novel oligonucleotides that enhance silencing of the expression of a gene containing a single nucleotide polymorphism (SNP) relative to the expression of the corresponding wild-type gene are provided. Methods of using novel oligonucleotides that enhance silencing of the expression of a gene containing a SNP relative to the expression of the corresponding wild-type gene are provided. |
| FILED | Friday, August 09, 2019 |
| APPL NO | 16/537374 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/312 (20130101) C12N 2310/351 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767528 | Borrajo |
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| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jacob Borrajo (Cambridge, Massachusetts) |
| ABSTRACT | This disclosure provides compositions and methods of using these compositions to mediate a targeted trans-splicing event on a pre-mRNA in a cell. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 16/994230 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767530 | Burnett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | John C. Burnett (Chatsworth, California); Elizabeth Epps (Mission Viejo, California); John J. Rossi (Azusa, California) |
| ABSTRACT | Provided herein are, inter alia, oligonucleotides, kits, and methods useful for increasing lentiviral titers. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387064 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/1132 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/33 (20130101) C12N 2330/51 (20130101) C12N 2740/16043 (20130101) C12N 2740/16052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767551 | Bushkin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Yuri Bushkin (Croton-on-Hudson, New York); Maria L. Gennaro (New York, New York); Sanjay Tyagi (New York, New York); Richard Pine (Corinth, New York) |
| ABSTRACT | The present invention relates to a method for rapidly detecting copies of at least one RNA molecule expressed in individual cells and uses thereof. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144793 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) Original (OR) Class C12Q 1/6841 (20130101) C12Q 2565/626 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767557 | Love et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | J. Christopher Love (Somerville, Massachusetts); Todd Michael Gierahn (Brookline, Massachusetts); Alexander K. Shalek (Lexington, Massachusetts); Marc Havens Wadsworth (Somerville, Massachusetts); Travis K. Hughes (Cambridge, Massachusetts) |
| ABSTRACT | Modifications to both hardware and enzymatic reactions used in single cell analyses such as but not limited to Seq-well that enable significant increases in the yield of transcripts per cell, portability and ease of use, increased scalability of the assay, and linkage of transcript information to other measurements made in the picowell arrays are disclosed. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/213551 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 2200/0647 (20130101) B01L 2300/0681 (20130101) B01L 2300/0819 (20130101) B01L 2300/0829 (20130101) B01L 2300/0851 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1068 (20130101) C12N 15/1093 (20130101) C12N 15/1093 (20130101) C12N 15/1096 (20130101) C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/15 (20130101) C12Q 2525/155 (20130101) C12Q 2525/173 (20130101) C12Q 2525/191 (20130101) C12Q 2533/101 (20130101) C12Q 2533/101 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/2014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767564 | Chattopadhyay et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Chandrani Chattopadhyay (Houston, Texas); Janos Roszik (Houston, Texas) |
| ABSTRACT | Provided herein are methods for identifying expression of SDHA, MIF, and or monosomy 3 or disomy 3 status in sample to identify the sample as high-risk melanoma and/or the sensitivity to oxidative phosphorylation inhibitors. Also provided herein are methods for treating monosomy 3 uveal melanoma by administering a SDHA inhibitor in combination with an oxidative phosphorylation inhibitor. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/759265 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 103/05001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768150 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ji-Xin Cheng (Newton, Massachusetts); Lu Lan (Allston, Massachusetts); Jiaze Yin (Waltham, Massachusetts) |
| ABSTRACT | Systems and methods are provided for performing photothermal dynamic imaging. An exemplary method includes: scanning a sample to produce a plurality of raw photothermal dynamic signals; receiving the raw photothermal dynamic signals of the sample; generating a plurality of second signals by matched filtering the raw photothermal dynamic signals to reject non-modulated noise; and performing an inverse operation on the second signals to retrieve at least one thermodynamic signal in a temporal domain. |
| FILED | Friday, August 05, 2022 |
| APPL NO | 17/881996 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) G01N 21/47 (20130101) G01N 21/171 (20130101) Original (OR) Class G01N 2021/3595 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768174 | Xie et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Ping Xie (Needham, Massachusetts); Charles M. Lieber (Lexington, Massachusetts) |
| ABSTRACT | To sense the translocation of a molecule through a nanopore, there is directed to an inlet of the nanopore, having a nanopore fluidic resistance, RP, a molecule disposed in a cis fluidic ionic solution having a cis fluidic access resistance, RC. The molecule is caused to translocate through the nanopore from the inlet of the nanopore to an outlet of the nanopore and to a trans fluidic ionic solution having a trans fluidic access resistance, RT. The trans fluidic access resistance, RT, is of the same order of magnitude as the nanopore fluidic resistance, RP, and both RT and RP are at least an order of magnitude greater than the cis fluidic access resistance, RC. An indication of local electrical potential is produced at a site within the nanopore sensor that is on the trans fluidic ionic solution-side of the nanopore, to sense translocation of the molecule through the nanopore. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 17/732990 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2565/631 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) Original (OR) Class G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768196 | Ham et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Donhee Ham (Cambridge, Massachusetts); Jeffrey T. Abbott (Cambridge, Massachusetts); Hongkun Park (Cambridge, Massachusetts); Wenxuan Wu (Cambridge, Massachusetts) |
| ABSTRACT | Methods and systems for stimulating and monitoring electrogenic cells are described. Some systems for stimulating electrogenic cells are based on the injection of electric currents into the cells via electrodes connected to the cells. Such stimulators may comprise an impedance element having an input terminal and an output terminal coupled to an electrode, and a voltage follower coupled between the input terminal and the output terminal of the impedance element, the voltage follower being configured to maintain a substantially constant voltage between the input terminal and the output terminal of the impedance element. The impedance element may comprise one or more switched capacitors at least in some embodiments. In some embodiments, the voltage follower may be implemented using a source follower. |
| FILED | Friday, July 06, 2018 |
| APPL NO | 16/625603 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/053 (20130101) A61B 2562/0285 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/18 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/00 (20130101) G01N 33/48728 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768203 | Chaudhary |
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| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Preet M. Chaudhary (Toluca Lake, California) |
| ABSTRACT | Provided herein are methods for detecting an antigen or for detecting expression of a chimeric antigen receptor (CAR). The methods include obtaining a sample from a subject, contacting the sample with a fusion protein comprising a reporter fused to a single chain antibody specific to the antigen or fused to an extracellular domain of an antigen targeted by the CAR or fused to Protein L and assaying the activity of the reporter, wherein presence of reporter activity or increase in reporter activity relative to a reference value is indicative of presence of the antigen or presence of the expression of the chimeric antigen receptor in the sample. |
| FILED | Friday, March 31, 2017 |
| APPL NO | 16/089278 |
| ART UNIT | 1678 — Printing/Measuring and Testing |
| CURRENT CPC | Peptides C07K 16/2803 (20130101) C07K 16/2827 (20130101) C07K 16/2866 (20130101) C07K 16/2878 (20130101) C07K 16/2887 (20130101) C07K 16/2896 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/43 (20130101) C07K 2319/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/581 (20130101) G01N 33/5023 (20130101) G01N 33/5044 (20130101) G01N 33/56966 (20130101) G01N 33/56972 (20130101) Original (OR) Class G01N 2333/72 (20130101) G01N 2333/70503 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768208 | Sarwal et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Minnie M. Sarwal (Portola Valley, California); Tara Sigdel (Palo Alto, California); Amit Kaushal (Mountain View, California); Li Li (Stanford, California); Wenzhong Xiao (San Jose, California); Atul J. Butte (Menlo Park, California); Purvesh Khatri (Menlo Park, California) |
| ABSTRACT | Aspects of the present invention include methods for determining a transplant category of a subject having a transplant. Common mechanisms of rejection injury are uncovered across different tissue transplants, and provide a means to understand rational drug design. Various sources of tissues are examined form the patient for understanding AR mechanism (graft biopsy), as well as monitoring by minimal invasive means (blood) or non-invasive means (urine for the kidney allograft). For biomarker discovery different categories of markers are examined such as genes, proteins, peptides and antibodies. These biomarkers can help determine the subject's transplant category (e.g., acute allograft rejection (AR), stable allograft (STA), BK viremia, BK nephritis, drug toxicity or chronic allograft injury (CAI), and the like). Also provided are compositions, systems, kits and computer program products that find use in practicing the subject methods. The methods and compositions find use in a variety of applications. |
| FILED | Friday, January 29, 2021 |
| APPL NO | 17/162093 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768264 | Ma et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); University College Cardiff Consultants Limited (Cardiff, United Kingdom) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); University College Cardiff Consultants Limited Cardiff (Cardiff, United Kingdom) |
| INVENTOR(S) | Dan Ma (Solon, Ohio); Mark A. Griswold (Shaker Heights, Ohio); Derek Jones (Cardiff, United Kingdom); Maryam Afzali (Cardiff, United Kingdom); Lars Mueller (Cardiff, United Kingdom) |
| ABSTRACT | A method for multi-dimensional, relaxation-diffusion magnetic resonance fingerprinting (MRF) includes performing, using a magnetic resonance imaging (MRI) system, a pulse sequence that integrates free-waveform b-tensor diffusion encoding into a magnet resonance fingerprinting pulse sequence to perform a multi-dimensional, relaxation-diffusion encoding while acquiring MRF signal evolutions, processing, using a processor, the acquired MRF signal evolutions to determine at least one relaxation parameter and at least one diffusivity parameter, and generating, using the processor, a report including at least one of the at least one relaxation parameter and the at least diffusivity parameter. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/661736 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) Original (OR) Class G01R 33/5608 (20130101) G01R 33/56341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11768676 — Switching blood glucose control system execution without interruption of therapy delivery
| US 11768676 | Rosinko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beta Bionics, Inc. (Irvine, California) |
| ASSIGNEE(S) | Beta Bionics, Inc. (Irvine, California) |
| INVENTOR(S) | Michael J. Rosinko (Las Vegas, Nevada); Edward R. Damiano (Acton, Massachusetts); David Chi-Wai Lim (Irvine, California); Firas H. El-Khatib (Allston, Massachusetts); Himanshu Patel (Rancho Santa Margarita, California); John R. Costik (Livonia, New York); Justin P. Brown (Tustin, California); Bryan Dale Knodel (Flagstaff, Arizona) |
| ABSTRACT | Systems and methods are disclosed herein for switching control of an ambulatory medical device from an application executing on the ambulatory medical device to a safe version or a new version of the application without interrupting therapy provided by the ambulatory medical device to a subject. The ambulatory medical device can maintain copies of a safe version and a new version of the application. The disclosed systems and methods can execute the new version, while the prior version of the application continues to execute, determine whether a minimum set of operating conditions are satisfied by the new version, and switch control of the ambulatory medical device from the prior version to the new version. The systems and methods can also automatically revert to the safe version of the application case the current version is malfunctioning without interrupting therapy provided to the subject. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478146 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/172 (20130101) A61M 5/1723 (20130101) A61M 5/14244 (20130101) A61M 5/14248 (20130101) A61M 5/16831 (20130101) A61M 2005/1726 (20130101) A61M 2005/14208 (20130101) A61M 2205/18 (20130101) A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/505 (20130101) A61M 2205/581 (20130101) A61M 2205/582 (20130101) A61M 2205/583 (20130101) A61M 2205/609 (20130101) A61M 2205/3327 (20130101) A61M 2205/3546 (20130101) A61M 2205/3553 (20130101) A61M 2205/3584 (20130101) A61M 2205/3592 (20130101) A61M 2230/201 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) G06F 3/04883 (20130101) G06F 8/61 (20130101) G06F 8/65 (20130101) G06F 8/656 (20180201) Original (OR) Class G06F 21/31 (20130101) G06F 21/84 (20130101) G06F 21/305 (20130101) G06F 21/6245 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) G08B 21/0453 (20130101) G08B 25/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/00 (20180101) G16H 40/40 (20180101) G16H 40/60 (20180101) G16H 40/67 (20180101) G16H 50/30 (20180101) G16H 80/00 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/088 (20130101) H04L 63/101 (20130101) H04L 67/34 (20130101) Wireless Communication Networks H04W 76/10 (20180201) H04W 76/14 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768949 | Sadeh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Norman Sadeh (Pittsburgh, Pennsylvania); Bin Liu (Pittsburgh, Pennsylvania); Anupam Das (Pittsburgh, Pennsylvania); Martin Degeling (Pittsburgh, Pennsylvania); Florian Schaub (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system and method configures permission settings for applications (“apps”) running on a computing device of a user. A data center generates at least one model of collective privacy preferences. The computing device is in communication with the data center via a communications network. The computing device comprises a processor that execute at least a first app that requests access to at least one permission of the computing device and a personal privacy assistant app. The personal privacy assistant app receives the at least one model from the one or more servers of the data center; collects information about the user; identifies at least one recommended permission setting for the first app based on the at least one model and such that the recommended permission setting is user-specific; and configures the computing device to implement the received at least one user-specific recommended permission setting. |
| FILED | Tuesday, February 02, 2021 |
| APPL NO | 17/165775 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/604 (20130101) Original (OR) Class G06F 21/629 (20130101) G06F 21/6245 (20130101) Computer Systems Based on Specific Computational Models G06N 7/00 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/101 (20130101) H04L 63/102 (20130101) H04L 67/12 (20130101) H04L 67/306 (20130101) H04L 67/535 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769316 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Stowers Institute for Medical Research (Kansas City, Missouri) |
| ASSIGNEE(S) | Stowers Institute for Medical Research (Kansas City, Missouri) |
| INVENTOR(S) | Congrong (Ron) Yu (Leawood, Kansas); Rishabh Raj (Kansas City, Missouri); Dar Wilbur Dahlen (Albany, California) |
| ABSTRACT | This disclosure relates to the use of “pseudo-images” to perform image recognition, e.g., to perform facial image recognition. In an embodiment, the pseudo-image is obtained by starting with a real world image and, after optional preprocessing, subjecting the image to a non-linear transformation that converts the image into a pseudo-image. While real world objects (or, more generally, real world patterns) may be perceivable in the starting image, they cannot be perceived in the pseudo-image. Image recognition takes place by comparing the pseudo-image with a library of known pseudo-images, i.e., image recognition takes place in pseudo-image space without a return to real world space. In this way, robust image recognition is achieved even for imperfect real world images, such as, real world images that have been degraded by noise, poor illumination, uneven lighting, and/or occlusion, e.g., the presence of glasses, scarves, or the like in the case of facial images. |
| FILED | Saturday, August 07, 2021 |
| APPL NO | 17/396667 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/7715 (20220101) Original (OR) Class G06V 40/169 (20220101) G06V 40/172 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11766218 | Hassan-Ali et al. |
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| FUNDED BY |
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| APPLICANT(S) | Flex Ltd. (Singapore, Singapore) |
| ASSIGNEE(S) | Flex Ltd. (Singapore, Singapore) |
| INVENTOR(S) | Mudhafar Hassan-Ali (Menlo Park, California); Connor Meehan (Richardson, Texas); Phuocan N. Nguyen (Milpitas, California); Anthony Joseph Piazza (San Jose, California); Yolita C. Nugent (Chestnut Hill, Massachusetts); Adam M. Whiton (Chestnut Hill, Massachusetts); Jeffrey B. Cross (Aptos, California); Biren Salunke (Milpitas, California); Syed Muhammad Abdullah (Frisco, Texas); Allison E. Bowles (Boston, Massachusetts); Dennis T. Nguyen (Allen, Texas); Mark A. Bergman (Redwood City, California) |
| ABSTRACT | Embodiments of the disclosure provide systems and methods for a garment comprising a fabric layer, a plurality of biometric sensors integrated into the fabric layer, and a connectivity layer integrated into the fabric layer. The connectivity layer can comprise signal conductors and power conductors coupled with each of the plurality of biometric sensors. The garment can further comprise a power source coupled with each of the power conductors and providing, via the power conductors of the connectivity layer, electrical power to each of the plurality of biometric sensors, a signal monitor coupled with the connectivity layer and receiving, via the signal conductors of the connectivity layer, a signal comprising biometric information from each of the plurality of biometric sensors, and a gateway coupled with the signal monitor, the gateway receiving the biometric information from the signal monitor and providing the biometric information to an external computer system. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 16/427713 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/002 (20130101) A41D 13/02 (20130101) A41D 13/1281 (20130101) Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/25 (20210101) A61B 5/0059 (20130101) A61B 5/282 (20210101) A61B 5/296 (20210101) A61B 5/0809 (20130101) A61B 5/0816 (20130101) A61B 5/6804 (20130101) Original (OR) Class A61B 5/6843 (20130101) A61B 2562/0209 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766417 | Ari D'Agostino et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Csilla Ari D'Agostino (Tampa, Florida); Dominic Paul D'Agostino (Tampa, Florida) |
| ABSTRACT | Methods of treating anxiety disorders or reducing anxiety-related behaviors. The methods include administering a therapeutically effective amount of ketone supplementation, such as butanediol, ketone esters (e.g., 1,3-butanediol-acetoacetate diester) and/or ketone salts (e.g., beta-hydroxybutyrate-mineral salt), chronically, sub-chronically, or acutely, with or without admixture with a medium chain triglyceride or in combination. It was determined herein that ketone supplementation reduced anxiety in rats on elevated plus maze as measured by less entries to closed arms, more time spent in open arms, more distance travelled in open arms, and delayed latency to entrance to closed arms, when compared to control. Along with reducing anxiety-related behavior, the chronic, sub-chronic, and acute ketone supplements also caused significant elevation of blood βHB levels and changed blood glucose levels. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/234382 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/12 (20160801) A23L 33/16 (20160801) A23L 33/30 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/19 (20130101) A61K 31/22 (20130101) Original (OR) Class A61K 31/23 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766433 | Wipf et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Peter Wipf (Pittsburgh, Pennsylvania); James K. Johnson (Silver Spring, Maryland); Erin M. Skoda (Silver Spring, Maryland); Joel B. Nelson (Pittsburgh, Pennsylvania); Zhou Wang (Pittsburgh, Pennsylvania); Serene Tai (Pittsburgh, Pennsylvania); Keita Takubo (Pittsburgh, Pennsylvania); John Milligan (Philadelphia, Pennsylvania) |
| ABSTRACT | A compound, or a pharmaceutically acceptable salt or ester thereof, according to formula I: R20—(Z)b—(Y)c—(R21)a—(X)d—R22—R23 wherein R20 is aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a thio-containing group, or a seleno-containing group; Z is alkanediyl, substituted alkanediyl, cycloalkanediyl, or substituted cycloalkanediyl; Y is S, O, S(═O), —S(═O)(═O)—, or NR10, wherein R10 is H or alkyl; R21 is alkanediyl, substituted alkanediyl, cycloalkanediyl, substituted cycloalkanediyl, alkadienyl, substituted alkadienyl, cycloalkenediyl, substituted cycloalkenediyl, alkatrienyl, substituted alkatrienyl; X is —C(═O)—, —S(═O)(═O)—, or —N(H)C(═O)—; R22 includes at least one divalent amino radical; R23 is aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, alkoxy, aryloxy, a thio-containing group, or a seleno-containing group; a, b, c, and d independently are 0 or 1. |
| FILED | Wednesday, November 04, 2020 |
| APPL NO | 17/089519 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/47 (20130101) A61K 31/58 (20130101) A61K 31/122 (20130101) A61K 31/167 (20130101) A61K 31/401 (20130101) A61K 31/407 (20130101) A61K 31/497 (20130101) A61K 31/504 (20130101) Original (OR) Class A61K 31/4166 (20130101) A61K 31/4439 (20130101) A61K 31/4985 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766440 | Zuo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| ASSIGNEE(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| INVENTOR(S) | Jian Zuo (Omaha, Nebraska); Zhuo Li (Omaha, Nebraska) |
| ABSTRACT | In one aspect, use of compounds as active agents to treat a hearing impairment and to prevent a hearing impairment, and methods of treating and/or preventing hearing impairments or disorders using the compositions are disclosed. Momelotinib and Fedratinib exhibit excellent protection against antibiotic-induced hearing loss in zebrafish and mice when administered prophylactically. In one aspect, Momelotinib or Fedratinib can be used as a therapy for the treatment and/or prevention of hearing loss. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Monday, March 06, 2023 |
| APPL NO | 18/117852 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5377 (20130101) Original (OR) Class A61K 31/7036 (20130101) A61K 33/243 (20190101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766837 | Makeev |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Andrew Makeev (Arlington, Texas) |
| ABSTRACT | Disclosed herein are carbon-fiber reinforced polymeric composite and methods related thereto. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 17/606137 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/08 (20130101) Original (OR) Class B29C 70/025 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) B29K 2105/16 (20130101) B29K 2105/089 (20130101) B29K 2105/251 (20130101) B29K 2307/04 (20130101) B29K 2507/04 (20130101) B29K 2509/02 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/10 (20130101) C08J 5/042 (20130101) C08J 2363/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767096 | Walter |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Matthew W. Walter (Troy, Missouri) |
| ABSTRACT | A system for initiating a canopy release signal for a canopy of an aircraft includes a first striker secured to the canopy, and a first initiator assembly secured to a fuselage of the aircraft. The first initiator assembly has a protrusion. The first striker is configured to be rotated against the protrusion of the first initiator assembly. The canopy release signal is output in response to the first striker rotating against the protrusion of the first initiator assembly. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/530607 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/32 (20130101) Original (OR) Class B64C 1/1476 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767259 | Justus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Brian L. Justus (Springfield, Virginia); Alan L. Huston (Aldie, Virginia); Barbara A. Marcheschi (Fairfax Station, Virginia) |
| ABSTRACT | A copper-doped glass formed by placing a target glass in a container, surrounding the target glass with a powder mixture comprised of SiO2 powder and Cu2S powder, wherein the SiO2 powder and the Cu2S powder are mixed according to the formula (SiO2)(1-x)(Cu2S)x, where 0.01<x<0.1, and heated to a temperature of between 800° C. and 1150° C. for a duration of between 1 and 10 hours. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/117681 |
| ART UNIT | 1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/06 (20130101) C03C 3/076 (20130101) C03C 4/12 (20130101) C03C 14/006 (20130101) C03C 21/008 (20130101) C03C 23/002 (20130101) Original (OR) Class C03C 2201/40 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) C09K 11/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767301 | Spiegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); David Caianiello (Brooklyn, New York) |
| ABSTRACT | The present invention is directed to bi-functional compounds which find use as pharmaceutical agents in the treatment of disease states and/or conditions which are mediated through macrophage migration inhibitory factor (MIF) or immunoglubin G (IgG). The present invention is also directed to pharmaceutical compositions which comprise these bi-functional compounds as well as methods for treating disease states and/or conditions which are mediated through MIF/IgG or where MIF/IgG is a contributing factor to the development and perpetuation of diseases and/or conditions, especially including autoimmune diseases and cancer, among others. The purpose of the present invention is to provide a molecular strategy to lower plasma MIF/IgG level in patients with autoimmune diseases or certain types of cancers. The bi-functional molecule construct is comprised of a MIF/IgG-targeting motif, that is derived from small molecule MIF/IgG ligands, and an ASGPr-targeting motif that binds to hepatocyte asialoglycoprotein receptor (ASGPr). The compounds selectively bind MIF or IgG in plasma and subsequently engage the endo-lysosomal pathway of hepatocytes through ASGPr. As a consequence, MIF/IgG is internalized and degraded by hepatocytes, thus resulting in potential attenuation of corresponding disease symptoms which are modulated through MIF/IgG. |
| FILED | Monday, April 08, 2019 |
| APPL NO | 17/046192 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 249/04 (20130101) Original (OR) Class C07D 413/14 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767473 | Yao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Tianyi Yao (Exton, Pennsylvania); Kathleen J Stebe (Penn Valley, Pennsylvania) |
| ABSTRACT | Provided are compositions that include a nematic colloid, the nematic colloid comprising a nematic liquid crystal and a key colloid; and a lock colloid, the lock colloid optionally having at least two arms extending therefrom, the lock colloid being configured for assembly with the key colloid of the nematic colloid, the assembly optionally being mediated by a dipole interaction between the colloid and the lock colloid, by a disinclination line of the nematic colloid, or any combination thereof. Also provided are related methods. The disclosed compositions and methods can be used to, e.g., assemble chain and lattice structures from the key colloids by exploiting disinclination lines and dipole defects of the components of the compositions. |
| FILED | Wednesday, May 25, 2022 |
| APPL NO | 17/664911 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/00 (20130101) C09K 19/0208 (20130101) Original (OR) Class C09K 2323/031 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767498 | Bobrow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Johanna Bobrow (Somerville, Massachusetts); Todd Thorsen (Carlisle, Massachusetts); David Walsh (Boston, Massachusetts); Christina Zook (Tewksbury, Massachusetts); Min Jae Song (Laytonsville, Maryland); Marc Ferrer-Alegre (Potomac, Maryland); Sam Michael (Germantown, Maryland); Yen-Ting Tung (Derwood, Maryland); Molly Elizabeth Boutin (Troy, New York) |
| ABSTRACT | An in vitro tissue plate may include a well plate, a fluidic plate disposed on a bottom surface of the well plate, and a media manifold disposed on a bottom surface of the fluidic plate. The well plate may have at least two wells, including a tissue well and a waste well. The fluid plate may include a fluid channel extending between and fluidly connecting the tissue well to the waste well. The media manifold may include a one or more media outlets fluidly connected to the fluid channel. A tissue layer may be deposited in the tissue well. The tissue layer may include human cells such as neurovascular cells. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 16/912941 |
| ART UNIT | 1799 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 2300/0829 (20130101) B01L 2300/0861 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) Original (OR) Class C12M 23/40 (20130101) C12M 25/14 (20130101) C12M 29/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767501 | Hazlebeck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Global Algae Technologies, LLC (Santee, California) |
| ASSIGNEE(S) | GLOBAL ALGAE TECHNOLOGY, LLC (Santee, California) |
| INVENTOR(S) | David A. Hazlebeck (El Cajon, California); William Rickman (Lebanon, Tennessee) |
| ABSTRACT | Algae harvesting and cultivating systems and methods for producing high concentrations of algae product with minimal energy. In an embodiment, a dead-end filtration system and method includes at least one tank and a plurality hollow fiber membranes positioned in the at least one tank. An algae medium is pulled through the hollow fiber membranes such that a retentate and a permeate are produced. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/896632 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/22 (20130101) B01D 61/146 (20220801) B01D 63/02 (20130101) B01D 63/04 (20130101) B01D 63/046 (20130101) B01D 65/02 (20130101) B01D 2311/04 (20130101) B01D 2311/06 (20130101) B01D 2311/2626 (20130101) B01D 2311/2688 (20130101) B01D 2313/18 (20130101) B01D 2313/26 (20130101) B01D 2313/50 (20130101) B01D 2315/06 (20130101) B01D 2315/08 (20130101) B01D 2317/02 (20130101) B01D 2317/022 (20130101) B01D 2321/04 (20130101) B01D 2321/18 (20130101) B01D 2321/40 (20130101) B01D 2321/185 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/02 (20130101) C12M 29/04 (20130101) C12M 29/16 (20130101) C12M 29/18 (20130101) C12M 29/20 (20130101) C12M 33/14 (20130101) C12M 41/32 (20130101) C12M 41/44 (20130101) C12M 41/48 (20130101) C12M 45/00 (20130101) C12M 47/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/02 (20130101) C12N 1/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767557 | Love et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | J. Christopher Love (Somerville, Massachusetts); Todd Michael Gierahn (Brookline, Massachusetts); Alexander K. Shalek (Lexington, Massachusetts); Marc Havens Wadsworth (Somerville, Massachusetts); Travis K. Hughes (Cambridge, Massachusetts) |
| ABSTRACT | Modifications to both hardware and enzymatic reactions used in single cell analyses such as but not limited to Seq-well that enable significant increases in the yield of transcripts per cell, portability and ease of use, increased scalability of the assay, and linkage of transcript information to other measurements made in the picowell arrays are disclosed. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/213551 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 2200/0647 (20130101) B01L 2300/0681 (20130101) B01L 2300/0819 (20130101) B01L 2300/0829 (20130101) B01L 2300/0851 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1068 (20130101) C12N 15/1093 (20130101) C12N 15/1093 (20130101) C12N 15/1096 (20130101) C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/15 (20130101) C12Q 2525/155 (20130101) C12Q 2525/173 (20130101) C12Q 2525/191 (20130101) C12Q 2533/101 (20130101) C12Q 2533/101 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/2014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767770 | Nevinsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Michael D. Nevinsky (Philadelphia, Pennsylvania); David T. Misciagna (West Chester, Pennsylvania); Joseph Orso (Glen Mills, Pennsylvania); Robert A. DiChiara, Jr (Carlsbad, California); Marc Daniel Spiccia Karasek (Media, Pennsylvania) |
| ABSTRACT | A system and method for mitigating thermal loading between engine exhaust structures having different coefficients of thermal expansion. The engine exhaust structure comprises a metallic duct portion, a ceramic duct portion, and a double bipod fitting joining the metallic duct portion to the ceramic duct portion. The double bipod fitting is capable of flexing and taking up the thermal expansion differences between the joined metallic and ceramic ducts across the full temperature spectrum that an engine exhaust structure will experience in service. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/444759 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/243 (20130101) Original (OR) Class Jet-propulsion Plants F02K 1/80 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768196 | Ham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Donhee Ham (Cambridge, Massachusetts); Jeffrey T. Abbott (Cambridge, Massachusetts); Hongkun Park (Cambridge, Massachusetts); Wenxuan Wu (Cambridge, Massachusetts) |
| ABSTRACT | Methods and systems for stimulating and monitoring electrogenic cells are described. Some systems for stimulating electrogenic cells are based on the injection of electric currents into the cells via electrodes connected to the cells. Such stimulators may comprise an impedance element having an input terminal and an output terminal coupled to an electrode, and a voltage follower coupled between the input terminal and the output terminal of the impedance element, the voltage follower being configured to maintain a substantially constant voltage between the input terminal and the output terminal of the impedance element. The impedance element may comprise one or more switched capacitors at least in some embodiments. In some embodiments, the voltage follower may be implemented using a source follower. |
| FILED | Friday, July 06, 2018 |
| APPL NO | 16/625603 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/053 (20130101) A61B 2562/0285 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/18 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/00 (20130101) G01N 33/48728 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768301 | Inglis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Silverside Detectors Inc (Waltham, Massachusetts) |
| ASSIGNEE(S) | Silverside Detectors Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Andrew Inglis (Brookline, Massachusetts); Alison Forsyth (Somerville, Massachusetts); Zachary S. Hartwig (Roslindale, Massachusetts); Philip C. Taber (Arlington, Massachusetts); Timothy Teal (Brighton, Massachusetts); Hidefumi Tomita (Pittsburgh, Pennsylvania) |
| ABSTRACT | A fissile neutron detection system includes an ionizing thermal neutron detector arrangement including an inner peripheral shape that at least substantially surrounds a moderator region for detecting thermal neutrons that exit the moderator region but is at least generally transparent to the incident fissile neutrons. A moderator is disposed within the moderator region having lateral extents such that any given dimension that bisects the lateral extents includes a length that is greater than any thickness of the moderator arrangement transverse to the lateral extents. The moderator can include major widthwise and major lengthwise lateral extents such that any given dimension across the lengthwise and widthwise lateral extents includes a length that is greater than any thickness of the moderator arrangement transverse to the lateral extents. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346894 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/00 (20130101) Original (OR) Class G01T 3/008 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 47/1233 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768365 | Greenwald |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Arlington, Virginia) |
| INVENTOR(S) | David Greenwald (O'Hara, Pennsylvania) |
| ABSTRACT | An optical element support system and a method of supporting an optical element are provided. The optical element includes an optical axis, an arcuate front surface, and a back surface. The optical element support system includes an axial support system that provides axial support to the optical element in a direction parallel to the optical axis of the optical element, and further includes a lateral support system that provides lateral support to the optical element in one or more directions perpendicular to the optical axis of the optical element that is offset from a center-of-gravity of the optical element. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/338356 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 7/02 (20130101) G02B 7/182 (20130101) G02B 23/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768384 | Lentz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | US Gov't as represented by Sec'y of Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Joshua Lentz (Niceville, Florida) |
| ABSTRACT | A cycloidal diffractive waveplate based star simulator generates a star field with very high precision star locations and accurate brightness. The present disclosure provides a star simulator that allows for a large FOV, modular, multi-star simulator capable of very high precision dynamic star locations for testing of high accuracy, large FOV star trackers. The system is composed of a light source, a polarization grating-based image [1], and an opto-mechanical system for steering the light. The light is projected onto a diffuse screen where the light is scattered, creating a functional point source at the screen. A star tracker or other device under test views the screen which has a multitude of projected spots (each with its own light source and beam steering device) positioned in a star field distribution appropriate for the simulated viewing direction. |
| FILED | Monday, January 03, 2022 |
| APPL NO | 17/567578 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/1842 (20130101) G02B 26/0891 (20130101) G02B 27/4261 (20130101) Original (OR) Class Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 21/142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768418 | Watts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Analog Photonics LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Analog Photonics LLC (Boston, Massachusetts) |
| INVENTOR(S) | Michael Watts (Hingham, Massachusetts); Ehsan Hosseini (Milton, Massachusetts); Christopher Poulton (Cambridge, Massachusetts); Erman Timurdogan (Somerville, Massachusetts) |
| ABSTRACT | An optical phase shifter may include a waveguide core that has a top surface, and a semiconductor contact that is laterally displaced relative to the waveguide core and is electrically connected to the waveguide core. A top surface of the semiconductor contact is above the top surface of the waveguide core. The waveguide core may include a p-type core region and an n-type core region. A p-type semiconductor region may be in physical contact with the n-type core region of the waveguide core, and an n-type semiconductor region may be in physical contact with the p-type core region of the waveguide core. A phase shifter region and a light-emitting region may be disposed at different depth levels, and the light-emitting region may emit light from a phase shifter region that is in a position adjacent to the light-emitting region. |
| FILED | Thursday, July 29, 2021 |
| APPL NO | 17/443971 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/1223 (20130101) G02B 6/29331 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) G02F 1/0151 (20210101) G02F 1/225 (20130101) Original (OR) Class G02F 1/292 (20130101) G02F 2203/10 (20130101) G02F 2203/20 (20130101) G02F 2203/24 (20130101) G02F 2203/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768462 | Mansoor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | METROLASER, INC. (Irvine, California) |
| ASSIGNEE(S) | METROLASER, INC. (Laguna Hills, California); NAVAIR LAKEHURST, NAVAL AIR WARFARE CENTER AD (LKE) (Joint Base MDL, New Jersey) |
| INVENTOR(S) | Mohammad Mansoor (Irvine, California); James Trolinger (Costa Mesa, California); Jacob George (Downey, California) |
| ABSTRACT | Embodiments described herein provide an integrated holographic reconstruction platform that enables a user to perform three-dimensional visualization of a phenomenon by reconstructing holograms using a combination of normalization and propagation algorithms, which yields better results with significantly less demanding processing time and computing resources. Specifically, the integrated holographic reconstruction platform may be implemented as an all-in-one computer software that includes software components of digital holographic reconstruction, de-twinning and optical distortion removal via a user-friendly graphical interface. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 17/374670 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/2202 (20130101) Original (OR) Class G03H 2001/2247 (20130101) G03H 2226/02 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) Image Data Processing or Generation, in General G06T 3/4023 (20130101) G06T 5/002 (20130101) G06T 5/006 (20130101) G06T 5/20 (20130101) G06T 2200/24 (20130101) G06T 2207/20056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768949 | Sadeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Norman Sadeh (Pittsburgh, Pennsylvania); Bin Liu (Pittsburgh, Pennsylvania); Anupam Das (Pittsburgh, Pennsylvania); Martin Degeling (Pittsburgh, Pennsylvania); Florian Schaub (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system and method configures permission settings for applications (“apps”) running on a computing device of a user. A data center generates at least one model of collective privacy preferences. The computing device is in communication with the data center via a communications network. The computing device comprises a processor that execute at least a first app that requests access to at least one permission of the computing device and a personal privacy assistant app. The personal privacy assistant app receives the at least one model from the one or more servers of the data center; collects information about the user; identifies at least one recommended permission setting for the first app based on the at least one model and such that the recommended permission setting is user-specific; and configures the computing device to implement the received at least one user-specific recommended permission setting. |
| FILED | Tuesday, February 02, 2021 |
| APPL NO | 17/165775 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/604 (20130101) Original (OR) Class G06F 21/629 (20130101) G06F 21/6245 (20130101) Computer Systems Based on Specific Computational Models G06N 7/00 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/101 (20130101) H04L 63/102 (20130101) H04L 67/12 (20130101) H04L 67/306 (20130101) H04L 67/535 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769040 | Shao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NVIDIA Corp. (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA CORP. (Santa Clara, California) |
| INVENTOR(S) | Yakun Shao (Santa Clara, California); Rangharajan Venkatesan (San Jose, California); Nan Jiang (St. Louis, Missouri); Brian Matthew Zimmer (Mountain View, California); Jason Clemons (Leander, Texas); Nathaniel Pinckney (Cedar Park, Texas); Matthew R Fojtik (Chapel Hill, North Carolina); William James Dally (Incline Village, Nevada); Joel S. Emer (Acton, Massachusetts); Stephen W. Keckler (Austin, Texas); Brucek Khailany (Austin, Texas) |
| ABSTRACT | A distributed deep neural net (DNN) utilizing a distributed, tile-based architecture implemented on a semiconductor package. The package includes multiple chips, each with a central processing element, a global memory buffer, and processing elements. Each processing element includes a weight buffer, an activation buffer, and multiply-accumulate units to combine, in parallel, the weight values and the activation values. |
| FILED | Friday, July 19, 2019 |
| APPL NO | 16/517431 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/544 (20130101) G06F 9/44505 (20130101) Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) Original (OR) Class G06N 3/082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769257 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Benjamin Lee Johnson (Brooklyn Park, Minnesota); Vibhor L Bageshwar (Minneapolis, Minnesota); Srivatsan Varadarajan (St. Louis Park, Minnesota) |
| ABSTRACT | In one embodiment, a vision aided navigation system comprises: at least one image sensor configured to produce image frames of a surrounding environment; a feature extractor configured to extract at least one image feature from a first image frame; a navigation filter configured to output a navigation solution based navigation data from a navigation device and changes in position of the image feature in the images; a feature tracker to receive the image frames and predict a location of the image feature in a subsequent image frame; a dynamic localized parameter adjuster to adjust at least one image parameter of the subsequent image frame; and wherein the feature tracker is configured so that when the image feature cannot be identified in the subsequent image frame within a bounded region around the predicted location, the dynamic localized parameter adjuster adjusts the at least one image parameter within the bounded region. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 16/426733 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/20 (20130101) G06T 7/246 (20170101) Original (OR) Class G06T 2207/30244 (20130101) G06T 2207/30252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769262 | Menozzi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| INVENTOR(S) | Alberico Menozzi (Raleigh, North Carolina); Chris F. Argenta (Cary, North Carolina); James B. Cook (Apex, North Carolina) |
| ABSTRACT | The described technology regards an augmented reality system and method for estimating a position of a location of interest relative to the position and orientation of a display, including receiving and selectively filtering a plurality of measurement vectors from a rate-gyroscope. Systems of the described technology include including a plurality of sensors, a processing module or other computation means, and a database. Methods of the described technology use data from the sensor package useful to accurately render graphical user interface information on a display. |
| FILED | Monday, June 06, 2022 |
| APPL NO | 17/833196 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/1654 (20200801) G01C 21/1656 (20200801) Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) G02B 27/0093 (20130101) G02B 2027/0138 (20130101) G02B 2027/0141 (20130101) G02B 2027/0181 (20130101) Electric Digital Data Processing G06F 1/163 (20130101) G06F 3/01 (20130101) G06F 3/011 (20130101) G06F 3/04817 (20130101) G06F 11/00 (20130101) Image Data Processing or Generation, in General G06T 5/20 (20130101) G06T 7/33 (20170101) Original (OR) Class G06T 11/00 (20130101) G06T 19/006 (20130101) G06T 2200/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769604 | Cumby et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Brad L Cumby (Liberty Township, Ohio); Christopher Tabor (Kettering, Ohio) |
| ABSTRACT | A deformable yet mechanically resilient microcapsule having electrical properties, a method of making the microcapsules, and a circuit component including the microcapsules. The microcapsule containing a gallium liquid metal alloy core having from about 60 to about 100 wt. % gallium and at least one alloying metal, and a polymeric shell encapsulating the liquid core, said polymeric shell having conductive properties. |
| FILED | Thursday, June 02, 2022 |
| APPL NO | 17/830463 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Alloys C22C 28/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) Original (OR) Class H01B 13/0036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769710 | Refai-Ahmed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | XILINX, INC. (San Jose, California) |
| ASSIGNEE(S) | XILINX, INC. (San Jose, California) |
| INVENTOR(S) | Gamal Refai-Ahmed (Santa Clara, California); Suresh Ramalingam (Fremont, California); Ken Chang (Los Altos Hills, California); Mayank Raj (Sunnyvale, California); Chuan Xie (Fremont, California); Yohan Frans (Palo Alto, California) |
| ABSTRACT | Some examples described herein provide for a heterogeneous integration module (HIM) that includes a thermal management apparatus. In an example, an apparatus (e.g., a HIM) includes a wiring substrate, a first component, a second component, and a thermal management apparatus. The first component and the second component are communicatively coupled together via the wiring substrate. The thermal management apparatus is in thermal communication with the first component and the second component. The thermal management apparatus has a first thermal energy flow path for dissipating thermal energy generated by the first component and has a second thermal energy flow path for dissipating thermal energy generated by the second component. The first thermal energy flow path has a lower thermal resistivity than the second thermal energy flow path. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 16/833034 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/473 (20130101) Original (OR) Class H01L 23/3675 (20130101) H01L 25/167 (20130101) H01L 2023/4062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769981 | O'Loughlin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico) |
| INVENTOR(S) | James Peter O'Loughlin (Placitas, New Mexico) |
| ABSTRACT | The embodiments disclosed herein reduce numerous active regulators (e.g., to only one) used in previous circuits that require regulated current and still accomplish the current regulation provided to each load by means of an array of autotransformers, and if required, rectifiers, and filters. Therefore, in an exemplary embodiment, there is eliminated the numerous active regulators by replacing them with simple passive components and an active regulator. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 16/833471 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 25/50 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0912 (20130101) Original (OR) Class H01S 3/0941 (20130101) H01S 5/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11770160 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland) |
| ASSIGNEE(S) | INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland) |
| INVENTOR(S) | Xingping Lin (Germantown, Maryland); Genshe Chen (Germantown, Maryland); Khanh Pham (Kirtland AFB, New Mexico); Erik Blasch (Arlington, Virginia); Zhonghai Wang (Germantown, Maryland) |
| ABSTRACT | A hidden chamber detector includes a linear frequency modulated continuous wave (LFMCW) radar, a synthetic aperture radar (SAR) imaging processor, and a time division multiple access (TDMA) multiple input multiple output (MIMO) antenna array, including a plurality of transmitting and receiving (Tx-Rx) antenna pairs. A Tx-Rx antenna pair is selected, in a time division manner, as a Tx antenna and an Rx antenna for the LFMCW radar. The LFMCW radar is configured to transmit an illumination signal, receive an echo signal, convert the echo signal to a baseband signal, collect baseband samples, and send the collected samples to the SAR imaging processor. The SAR imaging processor is configured to receive the collected samples, collect structure/configuration of the antenna array and scanning information, and form an SAR image based on the collected samples, the structure/configuration of the antenna array, and the scanning information. |
| FILED | Monday, March 09, 2020 |
| APPL NO | 16/813250 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/032 (20130101) G01S 7/354 (20130101) G01S 13/34 (20130101) Transmission H04B 7/0413 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11770347 | Pham |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Govt of the US as rep by the Secy of the Air Force (Wright Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Khanh Dai Pham (Albuquerque, New Mexico) |
| ABSTRACT | A dynamic heterogeneous network for transmitting media. The network has plural sources sending signals through various links and routers to plural destinations. Upon identifying a bottleneck link the network matches actual demand rate to actual service rate. A buffer setpoint is established to accommodate the difference between the demand rate and the service rate. The network determines an epoch having a penalty for deviation from the buffer setpoint. The rate allowance is reallocated to reduce the media bottleneck. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/653361 |
| ART UNIT | 2444 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/76 (20130101) Original (OR) Class H04L 47/129 (20220501) H04L 47/827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11770635 | Tantawy |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Senseics Corporation (Columbus, Ohio) |
| ASSIGNEE(S) | Senseics Corporation (Columbus, Ohio) |
| INVENTOR(S) | Ramy S. Tantawy (Columbus, Ohio) |
| ABSTRACT | An integrated circuit (IC) includes an analog to digital converter (ADC) circuit having an ADC input and an ADC output. The ADC circuit is configured to receive an input signal at the ADC input and generate a digital output signal at the ADC output based on the input signal. An ADC circuit path is coupled between the ADC input and the ADC output. The ADC circuit comprises a plurality of capacitors coupled between reference voltage sources and the ADC circuit path. The ADC has a reconfigurable resolution and a reconfigurable sampling rate. The ADC circuit is configured to scale the reference voltage sources and/or the plurality of capacitors based on the reconfigurable resolution. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/102941 |
| ART UNIT | 2696 — Selective Visual Display Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/129 (20130101) H03M 1/442 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11766203 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Philip Rocco Miller (Albuquerque, New Mexico); Ronen Polsky (Albuquerque, New Mexico); Nathaniel Bryant Pfeifer (Los Lunas, New Mexico) |
| ABSTRACT | The present invention is directed to devices including one or more hollow needles and a transducing wire disposed within at least one needle. In particular instances, arrays of such needles can be employed. Methods for fabricating and using such devices are also disclosed herein. |
| FILED | Monday, September 10, 2018 |
| APPL NO | 16/126039 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14503 (20130101) A61B 5/14532 (20130101) A61B 5/14539 (20130101) A61B 5/14865 (20130101) A61B 5/150022 (20130101) A61B 5/150282 (20130101) A61B 5/150396 (20130101) A61B 5/150984 (20130101) Original (OR) Class A61B 2562/028 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) A61M 2037/003 (20130101) A61M 2037/0053 (20130101) A61M 2037/0061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766651 | Walker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Charles A. Walker (Albuquerque, New Mexico); Peter D. D. Schwindt (Albuquerque, New Mexico); Grant Biedermann (Albuquerque, New Mexico); Dennis J. De Smet (Bosque Farms, New Mexico); Jongmin Lee (Albuquerque, New Mexico) |
| ABSTRACT | A sealed, passively pumped, polycrystalline ceramic vacuum chamber and method for fabricating the chamber are disclosed. The body of the vacuum chamber is made from a polycrystalline ceramic, for example, alumina. The vacuum chamber includes one or more windows made from a transparent ceramic, for example, sapphire, to accommodate optical access, while remaining amorphous-glass free to minimize or eliminate helium permeation. The vacuum chamber components are joined via laser welding or furnace brazing and the completed chamber is bakeable at temperatures up to 400° C. The vacuum chamber can operate at high or ultra-high vacuum pressures for an extended period through the use of one or more getter-based pumps. The vacuum chamber may include one or more atomic sources depending upon the application. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 16/840637 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 3/03 (20130101) B01J 3/004 (20130101) B01J 3/006 (20130101) Original (OR) Class Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/125 (20130101) Non-positive-displacement Pumps F04D 19/04 (20130101) Pistons; Cylinders; Sealings F16J 12/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766661 | Griffin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Michael Brandon Griffin (Denver, Colorado); Calvin Mukarakate (Arvada, Colorado); Maarit Kristiina Iisa (Golden, Colorado); Abhijit Dutta (Littleton, Colorado); Joshua A. Schaidle (Arvada, Colorado); Andrew Nolan Wilson (Denver, Colorado); Mark R. Nimlos (Golden, Colorado); Matthew Maurice Yung (Denver, Colorado) |
| ABSTRACT | The present disclosure relates to a catalyst that includes a support that includes a metal oxide and a metal deposited on the support, where the metal oxide includes at least one of TiO2, Al2O3, SiO2, CeO2, and/or ZrO2, the metal includes at least one of Pt, Pd, Ru Rh, Ni, and/or Mo, the metal is in the form of a particle, and the metal is present on the support at a concentration between about 0.1 wt % and about 5.0 wt %. |
| FILED | Wednesday, March 03, 2021 |
| APPL NO | 17/191370 |
| ART UNIT | 1738 — Optics |
| CURRENT CPC | Separation B01D 53/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) B01J 23/42 (20130101) Original (OR) Class B01J 35/08 (20130101) B01J 35/1014 (20130101) B01J 35/1038 (20130101) B01J 35/1042 (20130101) B01J 35/1057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767225 | Minguez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, New Caledonia) |
| INVENTOR(S) | Ignacio Luz Minguez (Durham, North Carolina); Mustapha Soukri (Cary, North Carolina); Marty Lail (Raleigh, North Carolina) |
| ABSTRACT | A method, comprising i) contacting an aqueous solution of an organic ligand salt of the formula AX(L−X) with a mesoporous material (MPM) to form an impregnated mesoporous salt material of the formula AX(L−X)/MPM, ii) treating the impregnated mesoporous salt material with an aqueous acidic solution to form an impregnated mesoporous acid material of the formula HX(L−X)/MPM, iii) contacting an aqueous solution of a metal precursor of the formula M+y(B)y with the impregnated mesoporous acid material to form an impregnated mesoporous metal organic framework precursor of the formula [M+y(B)y][Hx(L−x)]/MPM, and iv) at least one of 1) heating the impregnated mesoporous metal organic framework precursor in the absence of a solvent or 2) exposing the impregnated mesoporous metal organic framework precursor to a volatile vapor in the absence of a solvent such that the heating or the exposing forms a hybrid material of the formula (M+yL−x)/MPM, wherein the hybrid material comprises a nano-crystalline metal organic framework (MOF) embedded within the mesoporous material. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 16/324296 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 2253/108 (20130101) B01D 2253/204 (20130101) B01D 2259/4583 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) B01J 20/226 (20130101) B01J 20/3236 (20130101) B01J 20/3265 (20130101) B01J 29/06 (20130101) B01J 31/1691 (20130101) Non-metallic Elements; Compounds Thereof; C01B 39/00 (20130101) C01B 39/02 (20130101) C01B 39/026 (20130101) Original (OR) Class C01B 39/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767347 | Kong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Leopold Kong (Bethesda, Maryland); Ian A. Wilson (La Jolla, California); Natalia De Val (San Diego, California); Andrew B. Ward (San Diego, California); Dennis Burton (La Jolla, California); Linling He (San Diego, California); Jiang Zhu (San Diego, California) |
| ABSTRACT | The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 17/553070 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 47/64 (20170801) A61K 47/6929 (20170801) A61K 2039/645 (20130101) A61K 2039/5258 (20130101) A61K 2039/6031 (20130101) Peptides C07K 14/005 (20130101) C07K 14/162 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767468 | Sava Gallis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Dorina F. Sava Gallis (Albuquerque, New Mexico); Kimberly Butler (Albuquerque, New Mexico); Lauren E. S. Rohwer (Albuquerque, New Mexico) |
| ABSTRACT | Optical tags provide a way to identify assets quickly and unambiguously, an application relevant to anti-counterfeiting and protection of valuable resources or information. The present invention is directed to a tag fluorophore that encodes multilayer complexity in a family of heterometallic rare-earth metal-organic frameworks (RE-MOFs) based on highly connected polynuclear clusters and carboxylic acid-based linkers. Both overt (visible) and covert (near infrared, NIR) properties with concomitant multi-emissive spectra and tunable luminescence lifetimes impart both intricacy and security. Tag authentication can be validated with a variety of orthogonal detection methodologies. The relationships between structure, composition, and optical properties of the family of RE-MOFs can be used to create a large library of rationally designed, highly complex, difficult to counterfeit optical tags. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/479710 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/003 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 2211/10 (20130101) C09K 2211/182 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767501 | Hazlebeck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Global Algae Technologies, LLC (Santee, California) |
| ASSIGNEE(S) | GLOBAL ALGAE TECHNOLOGY, LLC (Santee, California) |
| INVENTOR(S) | David A. Hazlebeck (El Cajon, California); William Rickman (Lebanon, Tennessee) |
| ABSTRACT | Algae harvesting and cultivating systems and methods for producing high concentrations of algae product with minimal energy. In an embodiment, a dead-end filtration system and method includes at least one tank and a plurality hollow fiber membranes positioned in the at least one tank. An algae medium is pulled through the hollow fiber membranes such that a retentate and a permeate are produced. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/896632 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/22 (20130101) B01D 61/146 (20220801) B01D 63/02 (20130101) B01D 63/04 (20130101) B01D 63/046 (20130101) B01D 65/02 (20130101) B01D 2311/04 (20130101) B01D 2311/06 (20130101) B01D 2311/2626 (20130101) B01D 2311/2688 (20130101) B01D 2313/18 (20130101) B01D 2313/26 (20130101) B01D 2313/50 (20130101) B01D 2315/06 (20130101) B01D 2315/08 (20130101) B01D 2317/02 (20130101) B01D 2317/022 (20130101) B01D 2321/04 (20130101) B01D 2321/18 (20130101) B01D 2321/40 (20130101) B01D 2321/185 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/02 (20130101) C12M 29/04 (20130101) C12M 29/16 (20130101) C12M 29/18 (20130101) C12M 29/20 (20130101) C12M 33/14 (20130101) C12M 41/32 (20130101) C12M 41/44 (20130101) C12M 41/48 (20130101) C12M 45/00 (20130101) C12M 47/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/02 (20130101) C12N 1/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767521 | Eng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Thomas T. Eng (Berkeley, California); Deepanwita Banerjee (Emeryville, California); Aindrila Mukhopadhyay (Oakland, California) |
| ABSTRACT | The present invention provides for a genetically modified bacterial host cell capable of producing indigoidine, wherein the host cell comprises a non-ribosomal peptide synthetase (NRPS) that converts glutamine to indigoidine, and the bacterial host cell is reduced in its expression of one or more of the sixteen indicated enzymes. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180633 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) Original (OR) Class C12N 9/1217 (20130101) C12N 15/70 (20130101) C12N 15/78 (20130101) C12N 2310/20 (20170501) C12N 2510/02 (20130101) C12N 2511/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768012 | Rendall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Joseph D. Rendall (Oak Ridge, Tennessee); Kyle R. Gluesenkamp (Knoxville, Tennessee); Anthony C. Gehl (Knoxville, Tennessee); Jerald A. Atchley (Oak Ridge, Tennessee) |
| ABSTRACT | A diffuser for a water heater fill tubes having a tube wall with an outside diameter. The diffuser includes an elongated flexible diffuser body for positioning at the outlet end of the fill tube. The diffuser body has a sealing end for sealing with an outside surface of the fill tube wall closest to the inlet end of the fill tube, and an open end for positioning at an end closest to the outlet end of the fill tube. The open end has a diameter larger than an outside diameter of the tube wall, thereby creating an diffuser water outlet opening between the diffuser body and the tube wall for redirecting radial water flow emanating from the fill tube water outlet opening(s) toward the diffuser outlet opening. A fill tube assembly for a water heater, a water heater, and a method for heating water are also disclosed. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/193344 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Fluid Heaters, e.g Water or Air Heaters, Having Heat Generating Means, in General F24H 1/186 (20130101) F24H 9/0015 (20130101) Original (OR) Class F24H 9/133 (20220101) F24H 9/2035 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 2020/0069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768041 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado); University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a Body Corporate (Denver, Colorado); University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | Ronggui Yang (Boulder, Colorado); Xiaobo Yin (Boulder, Colorado); Gang Tan (Fort Collins, Colorado); Dongliang Zhao (Boulder, Colorado); Yaoguang Ma (Boulder, Colorado); Yao Zhai (Boulder, Colorado) |
| ABSTRACT | Polymer-based selective radiative cooling structures are provided which include a selectively emissive layer of a polymer or a polymer matrix composite material. Exemplary selective radiative cooling structures are in the form of a sheet, film or coating. Also provided are methods for removing heat from a body by selective thermal radiation using polymer-based selective radiative cooling structures, and a cold collection system comprising a plurality of the polymer-based selective radiative cooling structures. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/940031 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 17/10238 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/01 (20180101) C08K 3/36 (20130101) C08K 2201/005 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 5/0092 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/003 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/00 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/18 (20130101) Original (OR) Class F28F 2245/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768128 | Wissink et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Martin L. Wissink (Oak Ridge, Tennessee); Christopher L. Wray (San Antonio, Texas); Scott J. Curran (Oak Ridge, Tennessee); Ke An (Oak Ridge, Tennessee); Matthew J. Frost (Oak Ridge, Tennessee); Yan Chen (Oak Ridge, Tennessee) |
| ABSTRACT | An internal combustion engine for neutron diffraction analysis is provided. The engine includes an elongated piston chamber formed from an aluminum alloy to ensure maximum neutron visibility into the combustion chamber. An elongated piston assembly reciprocates within the elongated piston chamber, the piston assembly including an upper piston joined to a lower piston. The upper piston and the lower piston are hollow, thereby reducing the reciprocating mass and increasing neutron access to the combustion chamber. The upper piston is lubricated with a neutron-transparent fluorocarbon lubricant such as perfluoropolyether (PFPE), while the lower piston and the crankcase are lubricated with hydrocarbon lubricant. The engine enables 3D and time-resolved measurements of strain, stress, and temperature, as well as phase transformation, texture, and microstructure. |
| FILED | Tuesday, June 07, 2022 |
| APPL NO | 17/833989 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cooling of Machines or Engines in General; Cooling of Internal-combustion Engines F01P 3/02 (20130101) F01P 3/08 (20130101) F01P 2003/021 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 1/36 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/02 (20130101) G01M 15/042 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768164 | Lavens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Alex A Lavens (Frankfort, Illinois); Gyorgy Babnigg (Countryside, Illinois); Darren A. Sherrell (Naperville, Illinois); Andrzej Joachimiak (Bolingbrook, Illinois); Youngchang Kim (Naperville, Illinois); Jessica L Johnson (Plainfield, Illinois) |
| ABSTRACT | The invention provides a device for immobilizing and shipping crystals and for data collection via serial crystallography, the device having a first planar substrate defining a first transversely extending aperture, wherein the first substrate has a first laterally facing surface; a second planar substrate defining a second transversely extending aperture coaxial with the first aperture, wherein the second substrate has a second laterally facing surface; a third planar substrate and a fourth planar substrate positioned between the first and second substrates such that the first planar substrate, the second planar substrate, the third planar substrate and the fourth planar substrate are parallel; and a means for reversibly applying axial pressure to the first and second laterally facing surfaces so as to compress the third and fourth substrates together. |
| FILED | Wednesday, June 17, 2020 |
| APPL NO | 16/903601 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/207 (20130101) G01N 23/20025 (20130101) Original (OR) Class G01N 2223/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768340 | Patra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Susant K. Patra (Brentwood, California); Jonathan L. Dubois (Livermore, California) |
| ABSTRACT | The present disclosure relates to an interconnect system for interfacing an electronic subsystem to a qubit package, wherein the qubit package has a plurality of independent qubits. The system makes use of an optical fiber cable having a plurality of optical fibers, which is interfaced to the electronic subsystem. A 3D optical structure is used which has a plurality of internal waveguides, and which is configured to interface the optical fiber cable to the qubit package. The 3D optical structure further has at least one subsystem for using the plurality of waveguides to receive signals of a first type from at least one of the qubits package or the optical fiber cable, to convert the signals from the first type to a second type, and to transmit the signals in the second type to the other one of the fiber optic cable or the qubit package. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466581 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4249 (20130101) Original (OR) Class G02B 6/4269 (20130101) Optical Computing Devices; G06E 1/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768779 | Yin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Jieming Yin (Bothell, Washington); Yasuko Eckert (Redmond, Washington); Subhash Sethumurugan (Minneapolis, Minnesota) |
| ABSTRACT | Systems, apparatuses, and methods for cache management based on access type priority are disclosed. A system includes at least a processor and a cache. During a program execution phase, certain access types are more likely to cause demand hits in the cache than others. Demand hits are load and store hits to the cache. A run-time profiling mechanism is employed to find which access types are more likely to cause demand hits. Based on the profiling results, the cache lines that will likely be accessed in the future are retained based on their most recent access type. The goal is to increase demand hits and thereby improve system performance. An efficient cache replacement policy can potentially reduce redundant data movement, thereby improving system performance and reducing energy consumption. |
| FILED | Monday, December 16, 2019 |
| APPL NO | 16/716194 |
| ART UNIT | 2132 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/126 (20130101) Original (OR) Class G06F 2212/602 (20130101) G06F 2212/1021 (20130101) G06F 2212/1044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769055 | Shanthamallu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona); Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Uday Shanthamallu (Tempe, Arizona); Jayaraman Thiagarajan (Dublin, California); Andreas Spanias (Tempe, Arizona); Huan Song (Tempe, Arizona) |
| ABSTRACT | Various embodiments of systems and methods for attention models with random features for multi-layered graph embeddings are disclosed. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/739824 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9024 (20190101) G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/084 (20130101) Original (OR) Class G06N 3/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769070 | You et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Fengqi You (Ithaca, New York); Akshay Ajagekar (Ithaca, New York) |
| ABSTRACT | Technologies for a quantum/classical hybrid approach to solving optimization problems is disclosed. In the illustrative embodiment, an optimization problem is decomposed into two sub-problems. The first sub-problem is solved on a classical computer, and a result from the first sub-problem is provided to a quantum computer. The quantum computer then solves the second sub-problem based on the result of the first sub-problem from the classical computer. The quantum computer can then provide a result to the classical computer to re-solve the first problem. The iterative calculation is continued until an end condition is met. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/767247 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/60 (20220101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769600 | Stauff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Nicolas E. Stauff (Oak Park, Illinois); Yinbin Miao (Naperville, Illinois); Abdellatif M. Yacout (Naperville, Illinois); Taek K. Kim (Naperville, Illinois) |
| ABSTRACT | A heat transfer module can include an envelope sealed to define an internal volume that contains a working fluid and a wick disposed on an internal surface of the envelope. The wick and envelope each has a first portion extending through an evaporator region and a second portion extending through adiabatic and condenser regions. The first portion of the wick is a metal hydride. The first portion of the envelope includes a metal liner surrounding the first portion of the wick, a first diffusion barrier layer disposed between the first portion of the wick and the metal liner, and a ceramic matrix composite cladding surrounding the metal liner. The second portions of the wick and envelope each includes a refractory metal and/or stainless steel. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/011744 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/046 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/081 (20130101) Nuclear Reactors G21C 15/257 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769905 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Gui-Liang Xu (Downers Grove, Illinois); Jianzhao Liu (Lemont, Illinois); Zonghai Chen (Bolingbrook, Illinois); Khalil Amine (Oak Brook, Illinois) |
| ABSTRACT | An electrochemical device includes a cathode including elemental selenium, elemental sulfur, or selenium-sulfur containing composite; a negative electrode; a separator; and an electrolyte including a poly(alkyleneoxide) siloxane; and a salt; wherein a concentration of the salt in the electrolyte is sufficient to minimize dissolution of polysulfides/polyselenides formed during cycling of the device. |
| FILED | Monday, August 07, 2017 |
| APPL NO | 15/670295 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/30 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 10/054 (20130101) H01M 10/056 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 2300/0082 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769908 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhuoying Zhu (La Jolla, California); Shyue Ping Ong (La Jolla, California); Erik Wu (La Jolla, California); Han Nguyen (La Jolla, California); Ying Shirley Meng (La Jolla, California); Iek Heng Chu (La Jolla, California) |
| ABSTRACT | Presented are new, earth-abundant lithium superionic conductors, Li3Y(PS4)2 and Li5PS4Cl2, that emerged from a comprehensive screening of the Li—P—S and Li-M-P—S chemical spaces. Both candidates are derived from the relatively unexplored quaternary silver thiophosphates. One key enabler of this discovery is the development of a first-of-its-kind high-throughput first principles screening approach that can exclude candidates unlikely to satisfy the stringent Li+ conductivity requirements using a minimum of computational resources. Both candidates are predicted to be synthesizable, and are electronically insulating. Systems and methods according to present principles enable new, all-solid-state rechargeable lithium-ion batteries. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/528280 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/00 (20190201) G16C 20/30 (20190201) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11766480 | Kirshenbaum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Kent Kirshenbaum (New York, New York); Paul Michael Levine (New York, New York); Michael John Garabedian (New York, New York); Justin M. Holub (Athens, Ohio) |
| ABSTRACT | Novel peptoid oligomers are disclosed that have a formula represented by the following formula Ia or Ib: The peptoid oligomers are prepared as modulators of androgen receptor (AR), and may be prepared as pharmaceutical compositions and used for the prevention or treatment of a variety of conditions in mammals, including humans, associated with unwanted or aberrant AR activity. The present peptoid oligomers are particularly valuable for the treatment of subjects with cancer. |
| FILED | Wednesday, March 28, 2018 |
| APPL NO | 15/938418 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/55 (20170801) A61K 47/59 (20170801) A61K 47/64 (20170801) A61K 47/554 (20170801) Original (OR) Class Peptides C07K 5/0806 (20130101) C07K 5/1008 (20130101) C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 7/64 (20130101) C07K 14/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766663 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jingyue Liu (Scottsdale, Arizona); Xu Li (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jingyue Liu (Scottsdale, Arizona); Xu Li (Tempe, Arizona) |
| ABSTRACT | A nanocomposite catalyst includes a support, a multiplicity of nanoscale metal oxide clusters coupled to the support, and one or more metal atoms coupled to each of the nanoscale metal oxide clusters. Fabricating a nanocomposite catalyst includes forming nanoscale metal oxide clusters including a first metal on a support, and depositing one or more metal atoms including a second metal on the nanoscale metal oxide clusters. The nanocomposite catalyst is suitable for catalyzing reactions such as CO oxidation, water-gas-shift, reforming of CO2 and methanol, and oxidation of natural gas. |
| FILED | Wednesday, June 10, 2020 |
| APPL NO | 16/897871 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/10 (20130101) B01J 23/42 (20130101) B01J 23/44 (20130101) B01J 23/72 (20130101) B01J 23/75 (20130101) Original (OR) Class B01J 23/745 (20130101) B01J 35/0013 (20130101) B01J 35/1014 (20130101) B01J 37/0221 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/16 (20130101) C01B 3/40 (20130101) C01B 3/326 (20130101) C01B 32/50 (20170801) C01B 2203/107 (20130101) C01B 2203/0233 (20130101) C01B 2203/0261 (20130101) C01B 2203/0283 (20130101) C01B 2203/1082 (20130101) C01B 2203/1223 (20130101) C01B 2203/1241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766823 | Angelini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida); Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Thomas Ettor Angelini (Gainesville, Florida); Wallace Gregory Sawyer (Gainesville, Florida); Kyle Gene Rowe (Gainesville, Florida); Tapomoy Bhattacharjee (Kolkata, India); Alberto Fernandez-Nieves (Suwanee, Georgia); Ya-Wen Chang (Alpharetta, Georgia); Samantha M. Marquez (New Haven, Connecticut) |
| ABSTRACT | A method or apparatus for creating a three-dimensional tissue construct of a desired shape for repair or replacement of a portion of an organism. The method may comprise injecting at least one biomaterial in a three-dimensional pattern into a first material such that the at least one biomaterial is held in the desired shape of the tissue construct by the first material. The apparatus may comprise an injector configured to inject at least one biomaterial in a three-dimensional pattern into a first material such that the at least one biomaterial is held in the desired shape of the tissue construct by the first material. The first material may comprise a yield stress material, which may be a material exhibiting Herschel-Bulkley behavior. The tissue construct may have a smallest feature size of ten micrometers or less. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/233626 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/30942 (20130101) A61F 2002/30962 (20130101) A61F 2240/002 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) A61L 27/18 (20130101) A61L 27/26 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/60 (20130101) A61L 27/507 (20130101) A61L 27/3604 (20130101) A61L 27/3625 (20130101) A61L 2300/64 (20130101) A61L 2300/414 (20130101) A61L 2430/20 (20130101) A61L 2430/26 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7532 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) B33Y 80/00 (20141201) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/069 (20130101) C12N 5/0686 (20130101) C12N 2513/00 (20130101) C12N 2533/30 (20130101) C12N 2533/74 (20130101) C12N 2533/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767263 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Guoqiang Li (Baton Rouge, Louisiana); Harper Meng (Baton Rouge, Louisiana) |
| ABSTRACT | Provided is a method for altering properties of tension programmed fibrous shape memory polymer. The method can include applying a protective coating to the tension programmed shape memory polymer, then applying a supportive coating to the tension programmed shape memory polymer to form a coated fiber. The protective coating avoids contact between the shape memory polymer and chemicals used in the supportive coating that can decompensate the shape memory polymer. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 17/740779 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 73/18 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 20/1037 (20130101) C04B 26/04 (20130101) C04B 26/16 (20130101) Original (OR) Class C04B 26/26 (20130101) C04B 28/02 (20130101) C04B 2103/0065 (20130101) C04B 2111/72 (20130101) C04B 2111/00612 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/10 (20130101) C08G 18/664 (20130101) C08G 18/3206 (20130101) C08G 18/3206 (20130101) C08G 18/4238 (20130101) C08G 18/7671 (20130101) C08G 2110/0025 (20210101) C08G 2280/00 (20130101) C08G 2350/00 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/12 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767291 | Kattamuri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Padmanabha Venkatesh Kattamuri (Houston, Texas); Laszlo Kurti (Houston, Texas) |
| ABSTRACT | In one aspect, the present disclosure provides methods of preparing a secondary amine. In some embodiments, the secondary amine comprises two different groups or two identical groups. Also provided herein are compositions for use in the preparation of the secondary amine. |
| FILED | Thursday, May 17, 2018 |
| APPL NO | 16/614272 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 69/36 (20130101) C07C 69/675 (20130101) C07C 227/06 (20130101) C07C 229/04 (20130101) C07C 311/19 (20130101) Original (OR) Class C07C 381/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767302 | Fox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Delaware (Newark, Delaware) |
| ASSIGNEE(S) | UNIVERSITY OF DELAWARE (Newark, Delaware) |
| INVENTOR(S) | Joseph M. Fox (Landenberg, Pennsylvania); William Lambert (Gurnee, Illinois); Yinzhi Fang (Newark, Delaware); Christopher William am Ende (Mystic, Connecticut); Subham Mahapatra (Groton, Connecticut); Yixin Xie (Newark, Delaware); Chuanqi Wang (Newark, Delaware) |
| ABSTRACT | Disclosed herein are mono- and di-substituted tetrazines and methods of their preparation and converting an oxetanyl ester to a thio-substituted tetrazine, which is then converted to a mono-substituted tetrazine, a di-substituted tetrazine, or a vinylether disubstituted tetrazine. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 17/492016 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0298 (20130101) B01J 31/2265 (20130101) B01J 31/2409 (20130101) B01J 2531/824 (20130101) Heterocyclic Compounds C07D 257/08 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 401/14 (20130101) C07D 403/08 (20130101) C07D 405/04 (20130101) C07D 409/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Steroids C07J 43/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767516 | Melvin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | Board of Supervisors of Louisiana State University (Baton Rouge, Louisiana) |
| INVENTOR(S) | Adam Melvin (Baton Rouge, Louisiana); John Pojman (Baton Rouge, Louisiana); Anowar Khan (Baton Rouge, Louisiana) |
| ABSTRACT | Provided are thiol-acrylate hydrogels and tunable cell culture materials including thiol-acrylate hydrogels, and methods of making thereof. Also provided are systems for forming three-dimensional cell culture scaffolds including the materials, and methods of culturing cells, including cancer cells, using thiol-acrylate hydrogels and tunable cell culture materials. The materials herein can be used in microfluidic droplet-generating devices. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116289 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/04 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0693 (20130101) Original (OR) Class C12N 2500/05 (20130101) C12N 2500/34 (20130101) C12N 2513/00 (20130101) C12N 2533/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767523 | Krieg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Elisha Krieg (Dresden, Germany); William M. Shih (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are methods, compositions and kits for large-scale production of long single-stranded DNA in solution. |
| FILED | Monday, September 11, 2017 |
| APPL NO | 16/332674 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/56 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 2333/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) Original (OR) Class C12N 15/1017 (20130101) C12N 2310/00 (20130101) C12N 2330/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 2523/32 (20130101) C12Q 2523/32 (20130101) C12Q 2523/101 (20130101) C12Q 2523/101 (20130101) C12Q 2523/113 (20130101) C12Q 2523/113 (20130101) C12Q 2523/305 (20130101) C12Q 2525/204 (20130101) C12Q 2565/107 (20130101) C12Q 2565/107 (20130101) C12Q 2565/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767602 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Shaowei Chen (Santa Cruz, California); Forrest Nichols (Santa Cruz, California) |
| ABSTRACT | The catalyst composition includes graphitic carbon nitride and a plurality of platinum oxide nanoparticles disposed on the graphitic carbon nitride. |
| FILED | Wednesday, October 21, 2020 |
| APPL NO | 17/076004 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/052 (20210101) Original (OR) Class C25B 11/067 (20210101) C25B 11/075 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767604 | Pham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ELECTRASTEEL, INC. (Boulder, Colorado) |
| ASSIGNEE(S) | ELECTRASTEEL, INC. (Boulder, Colorado) |
| INVENTOR(S) | Ai Quoc Pham (Boulder, Colorado); Sandeep Nijhawan (Boulder, Colorado); Adolfredo Alvarez (Boulder, Colorado); Colleen Wallace (Boulder, Colorado); Steven Fatur (Boulder, Colorado) |
| ABSTRACT | Methods and systems for producing are disclosed. A method for producing iron, for example, comprises: providing an iron-containing ore to a dissolution subsystem comprising a first electrochemical cell; wherein the first anolyte has a different composition than the first catholyte; dissolving at least a portion of the iron-containing ore using an acid to form an acidic iron-salt solution having dissolved first Fe3+ ions; providing at least a portion of the acidic iron-salt solution to the first cathodic chamber; first electrochemically reducing said first Fe3+ ions in the first catholyte to form Fe2+ ions; transferring the formed Fe2+ ions from the dissolution subsystem to an iron-plating subsystem having a second electrochemical cell; second electrochemically reducing a first portion of the transferred formed Fe2+ ions to Fe metal at a second cathode of the second electrochemical cell; and removing the Fe metal. |
| FILED | Tuesday, August 09, 2022 |
| APPL NO | 17/884260 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/06 (20130101) C22B 5/00 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/06 (20130101) Original (OR) Class C25C 7/02 (20130101) C25C 7/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768420 | Tzang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Omer Tzang (Boulder, Colorado); Rafael Piestun (Boulder, Colorado); Antonio Miguel Caravaca-Aguirre (Boulder, Colorado); Kelvin Wagner (Boulder, Colorado) |
| ABSTRACT | Recent remarkable progress in wave-front shaping has enabled control of light propagation inside linear media to focus and image through scattering objects. In particular, light propagation in multimode fibers comprises complex intermodal interactions and rich spatiotemporal dynamics. Control of physical phenomena in multimode fibers and its applications is in its infancy, opening opportunities to take advantage of complex mode interactions. Various embodiments of the present technology provide wave-front shaping for controlling nonlinear phenomena in multimode fibers. Using a spatial light modulator at the fiber's input and a genetic algorithm optimization, some embodiments control a highly nonlinear stimulated Raman scattering cascade and its interplay with four wave mixing via a flexible implicit control on the superposition of modes that are coupled into the fiber. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/723196 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 29/46 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) Original (OR) Class G02F 1/3501 (20130101) G02F 1/3536 (20130101) G02F 2201/02 (20130101) G02F 2201/05 (20130101) G02F 2201/58 (20130101) G02F 2203/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768949 | Sadeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Norman Sadeh (Pittsburgh, Pennsylvania); Bin Liu (Pittsburgh, Pennsylvania); Anupam Das (Pittsburgh, Pennsylvania); Martin Degeling (Pittsburgh, Pennsylvania); Florian Schaub (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system and method configures permission settings for applications (“apps”) running on a computing device of a user. A data center generates at least one model of collective privacy preferences. The computing device is in communication with the data center via a communications network. The computing device comprises a processor that execute at least a first app that requests access to at least one permission of the computing device and a personal privacy assistant app. The personal privacy assistant app receives the at least one model from the one or more servers of the data center; collects information about the user; identifies at least one recommended permission setting for the first app based on the at least one model and such that the recommended permission setting is user-specific; and configures the computing device to implement the received at least one user-specific recommended permission setting. |
| FILED | Tuesday, February 02, 2021 |
| APPL NO | 17/165775 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/604 (20130101) Original (OR) Class G06F 21/629 (20130101) G06F 21/6245 (20130101) Computer Systems Based on Specific Computational Models G06N 7/00 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/101 (20130101) H04L 63/102 (20130101) H04L 67/12 (20130101) H04L 67/306 (20130101) H04L 67/535 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769055 | Shanthamallu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona); Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Uday Shanthamallu (Tempe, Arizona); Jayaraman Thiagarajan (Dublin, California); Andreas Spanias (Tempe, Arizona); Huan Song (Tempe, Arizona) |
| ABSTRACT | Various embodiments of systems and methods for attention models with random features for multi-layered graph embeddings are disclosed. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/739824 |
| ART UNIT | 2125 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9024 (20190101) G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/084 (20130101) Original (OR) Class G06N 3/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769548 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Muqing Liu (Minneapolis, Minnesota); Chen Zhou (Minneapolis, Minnesota); Keshab K. Parhi (Minneapolis, Minnesota); Hyung-il Kim (Minneapolis, Minnesota) |
| ABSTRACT | A method includes setting an output of each memory cell in an array of memory cells to a same first value, decreasing power to the array of memory cells and then increasing power to the array of memory cells. Memory cells in the array of memory cells with outputs that switched to a second value different from the first value are then identified in response to decreasing and then increasing the power. A set of memory cells is then selected from the identified memory cells to use in hardware security. |
| FILED | Thursday, March 10, 2022 |
| APPL NO | 17/691618 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 12/14 (20130101) G06F 21/44 (20130101) G06F 21/45 (20130101) G06F 21/73 (20130101) Static Stores G11C 11/417 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769908 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhuoying Zhu (La Jolla, California); Shyue Ping Ong (La Jolla, California); Erik Wu (La Jolla, California); Han Nguyen (La Jolla, California); Ying Shirley Meng (La Jolla, California); Iek Heng Chu (La Jolla, California) |
| ABSTRACT | Presented are new, earth-abundant lithium superionic conductors, Li3Y(PS4)2 and Li5PS4Cl2, that emerged from a comprehensive screening of the Li—P—S and Li-M-P—S chemical spaces. Both candidates are derived from the relatively unexplored quaternary silver thiophosphates. One key enabler of this discovery is the development of a first-of-its-kind high-throughput first principles screening approach that can exclude candidates unlikely to satisfy the stringent Li+ conductivity requirements using a minimum of computational resources. Both candidates are predicted to be synthesizable, and are electronically insulating. Systems and methods according to present principles enable new, all-solid-state rechargeable lithium-ion batteries. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/528280 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/00 (20190201) G16C 20/30 (20190201) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11769944 | Towfiq et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | i5 Technologies, Inc. (North Logan, Utah); Utah State University (Logan, Utah) |
| ASSIGNEE(S) | i5 Technologies, Inc. (North Logan, Utah); Utah State University (Logan, Utah) |
| INVENTOR(S) | Asaduzzaman Towfiq (North Logan, Utah); Bedri A. Cetiner (North Logan, Utah) |
| ABSTRACT | Among other things, a reconfigurable antenna array (RAA) includes individual pattern reconfigurable antennas (PRA). Each of the PRAs has (a) an antenna, (b) components controllable to generate and effect any of two or more modes of the PRA, the modes having respectively different steered radiation patterns, and (c) inputs to receive drive signals for the antenna and control signals for the controllable components. Control circuitry has outputs coupled to the inputs of the PRAs to drive the antennas of the PRAs to form an array beam having an array peak in a particular direction and at the same time to deliver control signals for the controllable components to effect a selected mode of each of the PRAs for which the steered radiation pattern has a peak in the particular direction of the array beam and has one or more nulls in the directions of one or more of the side-lobes of the array beam. |
| FILED | Thursday, December 30, 2021 |
| APPL NO | 17/566145 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/2617 (20130101) Original (OR) Class H01Q 9/0442 (20130101) H01Q 19/005 (20130101) H01Q 21/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11770399 | Charles et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Thelijjagoda S N Charles (Gainesville, Florida); Prabhat Kumar Mishra (Gainesville, Florida) |
| ABSTRACT | Various examples are provided related to software and hardware architectures that enable lightweight and trust-aware routing. In one example, among others, a method for trust-aware routing includes calculating trust values to represent how much a node can be trusted to route packets through its router. Each node can store the trust values of routers that are one hop and two hops away from it, which represent direct trust and delegated trust, respectively. When a router receives a packet, the router can update trust values and forward the packet to the next hop. |
| FILED | Tuesday, July 21, 2020 |
| APPL NO | 16/934612 |
| ART UNIT | 2442 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 15/7825 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 45/745 (20130101) H04L 49/109 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 69/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11766475 | Curtiss, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Roy Curtiss, III (Gainesville, Florida); Soo-Young Wanda (Gainesville, Florida) |
| ABSTRACT | Described herein are compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation, regulated expression of one or more antigens of interest, and/or N-glycan modification of secreted/surface antigens. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/207948 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/105 (20130101) A61K 39/205 (20130101) A61K 39/0275 (20130101) Original (OR) Class A61K 2039/58 (20130101) A61K 2039/70 (20130101) A61K 2039/522 (20130101) A61K 2039/523 (20130101) Peptides C07K 14/205 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) C12N 15/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11766476 | Gladue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Douglas P. Gladue (Guilford, Connecticut); Manuel V. Borca (Westbrook, Connecticut) |
| ABSTRACT | Provided herein are details on the construction of a recombinant African Swine Fever Virus (ASFV) live attenuated vaccine for prevention of ASF caused by various strains of ASFV, such as the highly virulent Georgia 2007 isolate (“ASFV-G”). An exemplary vaccine comprises a deletion of multiple genes allowing for industrial-scale growth in stable cell lines. |
| FILED | Tuesday, December 22, 2020 |
| APPL NO | 17/130814 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/04 (20130101) C12N 2710/12021 (20130101) C12N 2710/12034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11767289 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VMI Foundation (Lexington, Virginia); United States, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); THE VMI FOUNDATION (Lexington, Virginia) |
| INVENTOR(S) | Tappey H. Jones (Staunton, Virginia); Robert Kenneth Vander Meer (Newberry, Florida) |
| ABSTRACT | Methods and compositions for pest control, and more particularly for control of ants, e.g., of the subfamily Myrmicinae, using tyramides. |
| FILED | Monday, January 30, 2017 |
| APPL NO | 15/419899 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/18 (20130101) A01N 37/36 (20130101) A01N 37/42 (20130101) Acyclic or Carbocyclic Compounds C07C 233/18 (20130101) C07C 235/08 (20130101) C07C 235/74 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP35394 | Goffreda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Joseph C. Goffreda (Columbus, New Jersey); Anna M. Voordeckers (East Windsor, New Jersey) |
| ABSTRACT | A new and distinct peach variety of Prunus persica named ‘NJ362’ is provided. This variety is distinguished from other peach varieties by its unique combination of non-showy flowers, medium to large, round, freestone fruit, with a greyed-red to greyed-purple blush over a yellow-white ground, ripening in late-season, and possessing sweet, sub-acid flavor. |
| FILED | Monday, November 28, 2022 |
| APPL NO | 17/994602 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/196 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11767263 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Guoqiang Li (Baton Rouge, Louisiana); Harper Meng (Baton Rouge, Louisiana) |
| ABSTRACT | Provided is a method for altering properties of tension programmed fibrous shape memory polymer. The method can include applying a protective coating to the tension programmed shape memory polymer, then applying a supportive coating to the tension programmed shape memory polymer to form a coated fiber. The protective coating avoids contact between the shape memory polymer and chemicals used in the supportive coating that can decompensate the shape memory polymer. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 17/740779 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 73/18 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 20/1037 (20130101) C04B 26/04 (20130101) C04B 26/16 (20130101) Original (OR) Class C04B 26/26 (20130101) C04B 28/02 (20130101) C04B 2103/0065 (20130101) C04B 2111/72 (20130101) C04B 2111/00612 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/10 (20130101) C08G 18/664 (20130101) C08G 18/3206 (20130101) C08G 18/3206 (20130101) C08G 18/4238 (20130101) C08G 18/7671 (20130101) C08G 2110/0025 (20210101) C08G 2280/00 (20130101) C08G 2350/00 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/12 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768880 | Nemani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Ramakrishna Rao Nemani (Sunnyvale, California); Jia Zhang (Sunnyvale, California); Tseng-Dar John Lee (Burke, Virginia) |
| ABSTRACT | Community-driven, context-aware (e.g., geospatially and space-time aware) intelligent research assistant systems are provided. A virtual assistant application of a user computing system may receive a query from a user and provide the query to a server. The server may determine a category and topic of the query and determine whether an application exists for the category and topic. When the application exists, the server may call an application programming interface (API) associated with the application that executes finite state machine (FSM) logic to determine a context-aware answer to the query and provide the determined context-aware answer to the virtual assistant application. |
| FILED | Thursday, December 12, 2019 |
| APPL NO | 16/712982 |
| ART UNIT | 2161 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 9/453 (20180201) G06F 9/547 (20130101) G06F 16/9038 (20190101) Original (OR) Class G06F 16/24575 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11770066 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Bo Liu (Vernon, Connecticut); Yongduk Lee (Vernon, Connecticut); Xin Wu (Glastonbury, Connecticut); Suman Dwari (East Hartford, Connecticut) |
| ABSTRACT | A power converter can include a first line, a second line, a capacitor line disposed between the first line and the second line, a first capacitor and a second capacitor connected to the capacitor line in series between the first line and the second line, a midpoint line connected to a midpoint between the first capacitor and the second capacitor, and a protection circuit disposed between the first capacitor and the second capacitor and configured to provide protection to one or more portions of the power converter. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/345548 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/32 (20130101) Original (OR) Class H02M 7/217 (20130101) H02M 7/537 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11770184 | Bode et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ATLAS Space Operations, Inc. (Traverse City, Michigan) |
| ASSIGNEE(S) | ATLAS Space Operations, Inc. (Traverse City, Michigan) |
| INVENTOR(S) | Brad Arnold Bode (Pacific Palisades, California); Kyle Stephen Polich (Los Angeles, California) |
| ABSTRACT | Described herein are systems, methods, media, and devices for generating a satellite program for contacting satellites. In some embodiments, data including one or more targets for accessing a satellite constellation is obtained. Based on the data, a set of representations may be generated and candidate satellite constellation access programs may be determined based on the set of representations. For each program, a first score may be computed for each target to obtain a first set of scores, and a second score may be computed for each first score of the first set of scores to obtain a second set of scores. A satellite constellation access program may be selected from the candidate satellite access programs based on the second set of second scores. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/327068 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 7/18513 (20130101) H04B 7/18519 (20130101) H04B 7/18526 (20130101) H04B 7/18539 (20130101) H04B 7/18547 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11766294 | Gooding et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rachel Gooding (Herndon, Virginia); Alexander Dolan (Frederick, Maryland); David Bradley (Bel Air, Maryland); Kevin Wegman (Columbus, Ohio); Patrick Wilson (Dublin, Ohio); Brian Hawkins (Broomfield, Colorado); Timothy Davis (Atlanta, Georgia); Thomas Kirsch (Bethesda, Maryland) |
| ABSTRACT | A system to estimate consequences of an explosion includes a scenario generator to generate a scenario based on user input and scenario parameters; an explosive device model generator to generate an explosive device model based on the user input and explosive device parameters; a propagation of hazards modeler to model propagation of hazards into the scenario based on the user input and hazard parameters; an injury modeler to model injuries corresponding to modeling propagation of hazards into the scenario based on injury parameters; and an iteration and output generator to iterate by using additional iterative subsets of the parameters to generate the scenario, generate the explosive device model, model propagation of hazards, and model injuries, until parameter spaces of the parameters are covered. The iteration and output generator generates an injury record based injury outcomes from the modeling of injuries corresponding to the iterating. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/576471 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 2034/105 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11768117 | Hernandez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Hernandez (Springfield, Missouri); Karmen Noel Lappo (Albuquerque, New Mexico); Steven Wayne Bayley (Bosque Farms, New Mexico); Mark R. Nissen (Georgetown, Texas); Cole Sandin (Albuquerque, New Mexico); Allen Dean Gorby (Tijeras, New Mexico) |
| ABSTRACT | An apparatus for forming an anchor to connect a fiber to an explosive charge wall includes an anchor insert tab disposed on the interior side of the wall, a top plate disposed on the exterior side of the wall, an ST connector disposed on the exterior side and attached to the top plate to position the ST connector at the fiber insert wall opening for receiving the fiber, a plurality of zip ties extending through the anchor insert tab, the wall, and the top plate, and a plurality of locking members one for each of the zip ties. The zip ties each have a locking head disposed on the interior side of the wall to press the anchor insert tab against the interior wall surface. The locking members are engaged with the zip ties to press the top plate against the exterior wall surface to form the anchor. |
| FILED | Thursday, February 02, 2023 |
| APPL NO | 18/105137 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/14 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/227 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11770715 | Chung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Apple Inc. (Cupertino, California) |
| ASSIGNEE(S) | Apple Inc. (Cupertino, California) |
| INVENTOR(S) | Ho Cheung Chung (Sunnyvale, California); Gianpaolo Fasoli (Burlingame, California); Vinay Ganesh (San Jose, California); Irene M. Graff (Cupertino, California); Martijn Theo Haring (Utrecht, Netherlands); Ahmer A. Khan (San Jose, California); Franck Farian Rakotomalala (Dublin, California); Gordon Y. Scott (Cupertino, California) |
| ABSTRACT | An embodiment includes a method to increase the efficiency of security checkpoint operations. A security checkpoint kiosk serves as a Relying Party System (RPS). The RPS establishes a secure local connection between the RPS and a User Mobile-Identification-Credential Device (UMD). The RPS sends a user information request to the UMD, via the secure local connection, seeking release of user information associated with a Mobile Identification Credential (MIC). The RPS obtains authentication of the user information received in response to the user information request. The RPS retrieves user travel information based on the user information. The RPS determines that the user travel information matches the user information. When the user travel information matches the user information, the RPS approves the user to proceed past the security checkpoint kiosk. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/398723 |
| ART UNIT | 2496 — Selective Visual Display Systems |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Wireless Communication Networks H04W 4/80 (20180201) H04W 12/02 (20130101) H04W 12/037 (20210101) H04W 12/47 (20210101) H04W 12/69 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11768147 | Polyakov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Sergey Vladimirovich Polyakov (Gaithersburg, Maryland); Ivan Alexandrovich Burenkov (Germantown, Maryland); Yu-Hsiang Cheng (North Brunswick, New Jersey) |
| ABSTRACT | A quantum flow cytometer for detecting an analyte with photon-number statistics includes: a flow cytometer that: receives a pump light in a first direction; receives an analyte flow comprising the analyte in a second direction; and produces scattered light from scattering the pump light by the analyte; a single photon detector in optical communication with the flow cytometer and that: receives, in a third direction, the scattered light from the flow cytometer; provides a correlative time-of-arrival waveform comprising photon-number statistics as an amplitude and an integrated area, the integrated area being proportional to a number of photons received by the single photon detector, wherein the first direction, the second direction, and the third direction are arranged at oblique angles. |
| FILED | Thursday, May 20, 2021 |
| APPL NO | 17/325363 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 2015/1454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11767097 | Barrett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Ronald Martin Barrett (Lawrence, Kansas); Lauren Nicole Schumacher (Rolla, Missouri); Patrick Ian McNamee (Topeka, Kansas); John Austin Haug (Austin, Texas); Joshua Donald Mudd (Port St. Lucie, Florida); Dalton Bastiaan Prins (Clovis, California); Nicholas Donald Werner (Overland Park, Kansas) |
| ABSTRACT | A general mounting method for ducted fan propulsors is disclosed. This mounting method uses extremely slender stators that connect the duct ring to the propulsor which is mounted in the middle and drives the rotor, fan or propeller. The slender stators take the form of spokes and as such are so slender that the midspan stresses within the spokes are dominated by axial tension loads rather than the shear loads experienced by conventional stators. The spokes may have an aerodynamic shape and damping methods may be used to retard spoke vibrations and transmission of engine vibrations to the duct and force. The duct itself is also stiffened by the spoke arrangement, thereby reducing low frequency vibration modes. |
| FILED | Tuesday, April 16, 2019 |
| APPL NO | 17/047779 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 11/001 (20130101) B64C 11/008 (20130101) Original (OR) Class B64C 27/20 (20130101) B64C 33/00 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/04 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/96 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11766403 | Moudgil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Kamal D. Moudgil (Silver Springs, Maryland); Rakeshchandra R. Meka (Halethorp, Maryland) |
| ABSTRACT | The present invention relates in part to compositions for targeted delivery of an agent and agent delivery systems comprising a novel tissue-targeting peptide ligand (CKPFDRALC) (SEQ ID NO: 1) named ART-2. In certain aspects, the ART-2-coated liposomes encapsulating an agent, such as a therapeutic agent, diagnostic agent, imaging agent, or any combination thereof, were more effective in inhibiting, diagnosing, or imaging a disease or disorder, such as an arthritis progression, than control, despite a comparable safety profile. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 16/825371 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) Original (OR) Class A61K 38/08 (20130101) A61K 47/42 (20130101) A61K 47/64 (20170801) A61K 47/6911 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) Peptides C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 11768160 | Pellerin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES GEOLOGICAL SURVEY (Reston, Virginia) |
| ASSIGNEE(S) | U.S. Geological Survey (Reston, Virginia) |
| INVENTOR(S) | Brian Anthony Pellerin (Herndon, Virginia); Angela Merleen Hansen (Sacramento, California) |
| ABSTRACT | A multiparameter standard solution for verifying and calibrating water quality sensors containing an aqueous pH buffer, a xanthene dye, and distyryl biphenyl (DSBP) is provided. The standard solution provides a safe, quick, easy, and stable field standard to simultaneously conduct calibration analysis for several sensors at once. The standard solution is stable when stored and can be safely disposed of in the field. Methods of calibrating sensors used in water quality analysis using the multiparameter standard solution are also provided. |
| FILED | Saturday, November 21, 2020 |
| APPL NO | 17/100859 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/93 (20130101) Original (OR) Class G01N 33/18 (20130101) G01N 2201/13 (20130101) G01N 2201/12715 (20130101) G01N 2201/12746 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 11767508 | Ashton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Randolph Scott Ashton (Madison, Wisconsin); Gavin T. Knight (Coral Springs, Florida) |
| ABSTRACT | Described herein are methods, compositions, and kits for directed differentiation of human pluripotent stem cells, neuromesodermal progenitors, and neural stem cells into biomimetic neural tissues comprising one or more rosette structures. Preferably, the methods provided herein direct differentiation of human pluripotent stem cells, neuromesodermal progenitors, and neural stem cells into biomimetic neural tissues comprising a singular neural rosette structure that is comparable to at least a portion of the developing human neural tube. Also described are engineered neural tissue preparations comprising biomimetic neural tissues comprising a singular rosette structure having regional neural progenitor phenotypes. |
| FILED | Tuesday, July 24, 2018 |
| APPL NO | 16/044236 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 2501/41 (20130101) C12N 2501/115 (20130101) C12N 2501/119 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/03 (20130101) C12N 2513/00 (20130101) C12N 2533/30 (20130101) C12N 2533/90 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 11769224 | Moore et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Jerry O. Moore (Wylie, Texas); Matthew A. Schaefer (Rowlett, Texas) |
| ABSTRACT | A system mitigates transitions among pixels a mosaic image. The system uses two balancing adjustments and an easing transition adjustment. The first balancing adjustment uses a histogram to remap the pixels in the mosaic to a normal distribution. The second balancing adjustment minimizes transitions between adjacent individual images in the mosaic based on pixels positions of edge pixels and intensity differences between edge pixels in the adjacent images. The easing transitions adjustment modifies the intensity of a target pixel as a function of a radius from the target pixel, the distance between the target pixel and a nearest neighbor pixel, and an intensity difference between the nearest neighbor pixel and a pixel adjacent to the nearest neighbor pixel. A revised mosaic image is created as a function of the first balancing adjustment, the second balancing adjustment, and the easing transition adjustment. |
| FILED | Thursday, April 08, 2021 |
| APPL NO | 17/225566 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/4038 (20130101) Original (OR) Class G06T 5/40 (20130101) G06T 7/70 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 11770190 | Esman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| ASSIGNEE(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| INVENTOR(S) | Daniel J. Esman (Ellicott City, Maryland); Ronald D. Esman (Mclean, Virginia); Oliver S. King (Frederick, Maryland) |
| ABSTRACT | A system and related method for multiple-sensitivity optical phase modulation splits an optical carrier generated by a photonic source into at least two copies and directs the copies through an electro-optical (EO) phase modulator wherein the optical field associated with the optical carrier overlaps with a radio frequency (RF) electrical field associated with a radio frequency (RF) input signal, such that the EO modulator phase-modulates each optical copy according to the RF input signal of interest based on characteristics distinct to each optical copy (e.g., relative strength of, or proximity of the optical carrier to, the overlapping electrical field) that provide for phase modulation of each optical copy at a different sensitivity voltage. The variably modified optical copies are directed to a photonic processor for further signal processing in the optical domain. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/849087 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/035 (20130101) Transmission H04B 10/5561 (20130101) H04B 10/25759 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 11767291 | Kattamuri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Padmanabha Venkatesh Kattamuri (Houston, Texas); Laszlo Kurti (Houston, Texas) |
| ABSTRACT | In one aspect, the present disclosure provides methods of preparing a secondary amine. In some embodiments, the secondary amine comprises two different groups or two identical groups. Also provided herein are compositions for use in the preparation of the secondary amine. |
| FILED | Thursday, May 17, 2018 |
| APPL NO | 16/614272 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 69/36 (20130101) C07C 69/675 (20130101) C07C 227/06 (20130101) C07C 229/04 (20130101) C07C 311/19 (20130101) Original (OR) Class C07C 381/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11769345 | Raguin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HID Global Corporation (Austin, Texas) |
| ASSIGNEE(S) | HID Global Corporation (Austin, Texas) |
| INVENTOR(S) | Daniel Henri Raguin (North Palm Beach, Florida); George William McClurg (Jensen Beach, Florida); Aleksei Caesare Sebastiani (West Palm Beach, Florida); Markus Johannes Schiefele (Huntly, Virginia); Gregory Lewis Cannon (Lake Worth, Florida) |
| ABSTRACT | An apparatus for capturing an image of an object on a platen and including a platen having a surface for receiving the object, wherein the platen is transmissive to an optical wavelength of light, an illumination module configured to illuminate at least a portion of the object with light from an illumination source, and an optical sensing module configured to receive the light from the illumination source after the light interacts with the at least a portion of the object. The light from the illumination source is spatially patterned prior to reaching the object. The illumination module can be configured to create the spatially patterned illumination and/or the platen may include a patterned optical coating creating the spatially patterned illumination. The spatially patterned illumination can include a plurality of discrete areas (e.g., a stepped pattern) of different illumination intensity and/or a gradient of different illumination intensity. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 17/594931 |
| ART UNIT | 2621 — Selective Visual Display Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/0033 (20130101) Image or Video Recognition or Understanding G06V 10/143 (20220101) G06V 10/145 (20220101) G06V 10/774 (20220101) G06V 40/1318 (20220101) G06V 40/1324 (20220101) Original (OR) Class G06V 40/1394 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11768462 | Mansoor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | METROLASER, INC. (Irvine, California) |
| ASSIGNEE(S) | METROLASER, INC. (Laguna Hills, California); NAVAIR LAKEHURST, NAVAL AIR WARFARE CENTER AD (LKE) (Joint Base MDL, New Jersey) |
| INVENTOR(S) | Mohammad Mansoor (Irvine, California); James Trolinger (Costa Mesa, California); Jacob George (Downey, California) |
| ABSTRACT | Embodiments described herein provide an integrated holographic reconstruction platform that enables a user to perform three-dimensional visualization of a phenomenon by reconstructing holograms using a combination of normalization and propagation algorithms, which yields better results with significantly less demanding processing time and computing resources. Specifically, the integrated holographic reconstruction platform may be implemented as an all-in-one computer software that includes software components of digital holographic reconstruction, de-twinning and optical distortion removal via a user-friendly graphical interface. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 17/374670 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/2202 (20130101) Original (OR) Class G03H 2001/2247 (20130101) G03H 2226/02 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) Image Data Processing or Generation, in General G06T 3/4023 (20130101) G06T 5/002 (20130101) G06T 5/006 (20130101) G06T 5/20 (20130101) G06T 2200/24 (20130101) G06T 2207/20056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
| US 11766400 | Saltzman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut); Family Health International (Durham, North Carolina) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut); FAMILY HEALTH INTERNATIONAL (Durham, North Carolina) |
| INVENTOR(S) | W. Mark Saltzman (New Haven, Connecticut); Elias Quijano (Durham, Connecticut); Fan Yang (Branford, Connecticut); Zhaozhong Jiang (New Haven, Connecticut); Derek Owen (Durham, North Carolina) |
| ABSTRACT | Biodegradable contraceptive implants and methods of making and using thereof, are preferably formed of poly(ω-pentadecalactone-co-p-dioxanone) [poly(PDL-co-DO)], a family of polyester copolymers that degrade slowly in the presence of water. The material is suitable as the basis of a biodegradable contraceptive implant that provides sustained release of a progestin at a rate similar to a commercially available nondegradable implant. In a preferred embodiment, the progestin is levonorgestrel (LNG), a hormone that prevents pregnancy by preventing the release of an egg from the ovary or by preventing fertilization of the egg by sperm. The implant may be inserted subcutaneously, allowing degradation over a period of up to about 18 or 24 months, eliminating the need for removal by a trained practitioner. |
| FILED | Tuesday, October 24, 2017 |
| APPL NO | 16/344663 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) Original (OR) Class A61K 31/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11767760 | Conner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Richard David Conner (Peoria, Arizona); Ryan Cox (Gilbert, Arizona); Josef Merki (Chandler, Arizona); Brian Larsen (Downey, California) |
| ABSTRACT | A ram air turbine rotor comprises at least one intra-flow path shroud structure coupled between rotor blades, along a radial position between a support disc and an outer rim. The shroud structure includes shroud sectors each coupled between a respective pair of blades. The sectors each include a first edge adjacent to leading edges of the respective pair of blades, the first edge including a first curved segment, and a second edge adjacent to trailing edges of the respective pair of blades, the second edge including a second curved segment. The curved segments are each partially defined by a respective ellipse having a semi-major axis and a semi-minor axis. The semi-major axis is a portion of a spanwise distance between the respective pair of blades. The semi-minor axis is a portion of an axial distance between the leading edge of one blade and the trailing edge of an adjacent blade. |
| FILED | Wednesday, November 04, 2020 |
| APPL NO | 17/089564 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/03 (20130101) F01D 5/10 (20130101) Original (OR) Class F01D 5/022 (20130101) F01D 5/143 (20130101) Wind Motors F03D 1/0633 (20130101) F03D 9/32 (20160501) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2220/31 (20130101) F05B 2240/33 (20130101) F05B 2240/923 (20130101) F05B 2250/14 (20130101) F05B 2250/141 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 26, 2023.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20230926.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page