FedInvent™ Patents

Patent Details for Tuesday, October 10, 2023 

This page was updated on Tuesday, October 10, 2023 at 09:39 PM GMT

Department of Health and Human Services (HHS) 

US 11778995 Flavell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Regeneron Pharmaceuticals, Inc. (Tarrytown, New York);  Yale University (New Haven, Connecticut);  Institute for Research In Biomedicine (IRB) (Bellinzona, Switzerland)
ASSIGNEE(S) Regeneron Pharmaceuticals, Inc. (Tarrytown, New York);  Yale University (New Haven, Connecticut);  Institute for Research in Biomedicine (IRB) (Bellinzona, Switzerland)
INVENTOR(S) Richard Flavell (Guilford, Connecticut);  Till Strowig (Braunschweig, Germany);  Markus G. Manz (Zollikon, Switzerland);  Chiara Borsotti (Bronxville, New York);  Madhav Dhodapkar (New Haven, Connecticut);  Andrew J. Murphy (Croton-on-Hudson, New York);  Sean Stevens (San Diego, California);  George D. Yancopoulos (Yorktown Heights, New York)
ABSTRACT Genetically modified non-human animals are provided that may be used to model human hematopoietic cell development, function, or disease. The genetically modified non-human animals comprise a nucleic acid encoding human IL-6 operably linked to an IL-6 promoter. In some instances, the genetically modified non-human animal expressing human IL-6 also expresses at least one of human M-CSF, human IL-3, human GM-CSF, human SIRPa or human TPO. In some instances, the genetically modified non-human animal is immunodeficient. In some such instances, the genetically modified non-human animal is engrafted with healthy or diseased human hematopoietic cells. Also provided are methods for using the subject genetically modified non-human animals in modeling human hematopoietic cell development, function, and/or disease, as well as reagents and kits thereof that find use in making the subject genetically modified non-human animals and/or practicing the subject methods.
FILED Friday, August 21, 2020
APPL NO 17/000140
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0276 (20130101)
A01K 67/0278 (20130101) Original (OR) Class
A01K 2207/15 (20130101)
A01K 2217/15 (20130101)
A01K 2217/052 (20130101)
A01K 2217/072 (20130101)
A01K 2217/075 (20130101)
A01K 2227/105 (20130101)
A01K 2267/01 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0008 (20130101)

Peptides
C07K 14/524 (20130101)
C07K 14/535 (20130101)
C07K 14/5403 (20130101)
C07K 14/5412 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779218 Javitt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Daniel Javitt (Fort Lee, New Jersey);  Joan Prudic (New York, New York);  Stefan Rowny (New York, New York);  Marta Moreno (Hopewell Junction, New York)
ABSTRACT An exemplary system, method, and computer-accessible medium for determining a position or a characteristic of a target(s) for a transcranial magnetic stimulation (TMS) treatment of a patient(s) can be provided, which can include, for example, receiving imaging information of a portion(s) of a head of the patient(s), and determining the position or the characteristic of the target(s) for the TMS treatment of the patient(s) based on the imaging information. The imaging information can be magnetic resonance imaging information. The imaging information can include information regarding a brain and a skull of the patient(s). The position or the characteristic of the target(s) can be determined by identifying (i) the skull, and (ii) a parcel in a section(s) of a brain of the patient(s). The parcel can a dorsolateral prefrontal cortex (DLPFC) parcel. The DLPFC parcel can be identified using a parcellation procedure, which can be a human connectome pipeline procedure.
FILED Monday, April 25, 2022
APPL NO 17/728526
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0036 (20180801)
A61B 5/0042 (20130101) Original (OR) Class
A61B 5/055 (20130101)
A61B 5/165 (20130101)
A61B 5/167 (20130101)
A61B 5/4076 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2/006 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/30016 (20130101)
G06T 2210/41 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/30 (20180101)
G16H 20/70 (20180101)
G16H 30/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779219 Boppart et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Stephen A. Boppart (Champaign, Illinois);  Freddy T. Nguyen (Urbana, Illinois);  Adam M. Zysk (Chicago, Illinois)
ABSTRACT A system for providing intraoperative feedback to a user during the course of surgery. A core imaging unit provides low-coherence optical radiation coupled to a sampling device and generates optical coherence tomography (OCT) data based on combining scattered light received from the sampling device together with a reference signal. The sampling device is adapted to receive the low-coherence optical radiation from the core imaging unit and to illuminate the tissue, and to collect light scattered by the tissue and to return said light to the core imaging unit. A core software unit receives the OCT data from the core imaging unit provides real-time feedback, such as an image, to the user via an indicator.
FILED Thursday, December 20, 2018
APPL NO 16/227546
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0066 (20130101) Original (OR) Class
A61B 5/0073 (20130101)
A61B 5/415 (20130101)
A61B 5/418 (20130101)
A61B 5/6852 (20130101)
A61B 5/6853 (20130101)
A61B 5/7257 (20130101)
A61B 2562/0238 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779256 Schalk et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Health Research, Inc. (Menands, New York);  Albany Medical College (Albany, New York)
ASSIGNEE(S) HEALTH RESEARCH, INC. (Menands, New York);  ALBANY MEDICAL COLLEGE (Albany, New York)
INVENTOR(S) Gerwin Schalk (Glenmont, New York);  Anthony L. Ritaccio (Voorheesville, New York);  Adriana De Pesters (Coppet, Switzerland);  AmiLyn Taplin (Albany, New York)
ABSTRACT Provided is a method for mapping a neural area involved in speech processing, including applying a plurality of recording electrodes to a surface of a cortex of a human subject, presenting a plurality of auditory stimuli to the subject wherein some of the plurality of stimuli are speech sounds and others of the plurality of auditory stimuli are non-speech sounds, recording brain activity during the presenting of the plurality of auditory stimuli, and identifying one or more brain areas wherein activity changes more after presentation of speech sounds than it does after presentation of non-speech sounds, wherein the human subject does not speak during the presenting and the recording. Also provided is a method for mapping a neural area involved in speech production wherein the human subject does not speak during presenting speech stimuli and recording neural activity.
FILED Thursday, July 01, 2021
APPL NO 17/365032
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/03 (20130101) Original (OR) Class
A61B 5/4064 (20130101)
A61B 5/4094 (20130101)
A61B 2505/05 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/32 (20130101)
A61N 1/0531 (20130101)
A61N 1/36082 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/70 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779310 Dong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Huiming Dong (Columbus, Ohio);  Rizwan Ahmad (Hilliard, Ohio);  Arunark Kolipaka (Delaware, Ohio)
ABSTRACT Systems and methods for magnetic resonance elastography (MRE) are disclosed. In one embodiment, MRE data corresponding to mechanical waves in tissue of interest of a subject is acquired. The MRE data is associated with stiffness of the tissue. The method also includes generating, based on the MRE data, a stiffness map representing stiffness of the tissue. Generating the stiffness map includes performing an unconstrained optimization cost function that is configured to reduce noise in the acquired MRE data and achieve inversion of the reduced-noise data.
FILED Wednesday, May 08, 2019
APPL NO 16/406488
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/05 (20130101)
A61B 5/055 (20130101)
A61B 5/7257 (20130101)
A61B 8/485 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2291/02827 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/56358 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 15/8906 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779544 Maheshwari et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Akhil Maheshwari (Clarksville, Maryland);  Samuel Wickline (Temple Terrace, Florida);  Kopperuncholan Namachivayam (Cockeyesville, Maryland);  Hua Pan (Tampa, Florida)
ABSTRACT The present disclosure is directed to antithrombotic nanoparticles and methods of treating necrotizing enterocolitis.
FILED Monday, March 29, 2021
APPL NO 17/215668
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5123 (20130101) Original (OR) Class
A61K 31/401 (20130101)
A61K 38/1767 (20130101)
A61K 45/06 (20130101)
A61K 47/6929 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779548 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S) Jie Li (San Diego, California);  Zilei Liu (San Diego, California);  Suhua Li (Guangzhou, China PRC);  Peng Wu (San Diego, California);  K. Barry Sharpless (La Jolla, California)
ABSTRACT A high-throughput screening methods for identifying candidate anticancer medicinal agents is described herein. The candidate anticancer medicinal agents are arylfluorosulfate compounds derived from phenolic compounds. The method involves in situ generation of the arylfluorosulfate compounds in multi-well plates by reaction of phenolic compounds in DMSO with a saturated solution of SO2F2 dissolved in a solvent such as acetonitrile, in the presence of an organic base, followed by reaction of generated fluoride ion with trimethylsilanol to form volatile trimethylsilyl fluoride. Solvents, organic base, and silyl compounds are then removed, in vacuo, to afford the arylfluorosulfate compounds suitable for biological screening in cancer cell lines without further purification.
FILED Monday, May 11, 2020
APPL NO 16/871902
ART UNIT 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/05 (20130101) Original (OR) Class
A61K 31/14 (20130101)
A61K 31/40 (20130101)
A61K 31/47 (20130101)
A61K 31/53 (20130101)
A61K 31/56 (20130101)
A61K 31/65 (20130101)
A61K 31/70 (20130101)
A61K 31/136 (20130101)
A61K 31/197 (20130101)
A61K 31/198 (20130101)
A61K 31/397 (20130101)
A61K 31/407 (20130101)
A61K 31/439 (20130101)
A61K 31/473 (20130101)
A61K 31/485 (20130101)
A61K 31/505 (20130101)
A61K 31/515 (20130101)
A61K 31/655 (20130101)
A61K 31/4045 (20130101)
A61K 31/4168 (20130101)
A61K 31/4245 (20130101)
A61K 31/4353 (20130101)
A61K 31/4709 (20130101)
A61K 31/4745 (20130101)
A61K 31/5513 (20130101)
A61K 31/7048 (20130101)
A61K 38/31 (20130101)
A61K 47/54 (20170801)
A61K 51/0497 (20130101)

Acyclic or Carbocyclic Compounds
C07C 305/26 (20130101)
C07C 2601/14 (20170501)
C07C 2603/18 (20170501)

Heterocyclic Compounds
C07D 277/82 (20130101)
C07D 295/26 (20130101)
C07D 295/088 (20130101)
C07D 295/185 (20130101)

Peptides
C07K 1/02 (20130101)
C07K 1/1136 (20130101)
C07K 2/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0693 (20130101)
C12N 2503/02 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 30/04 (20130101)
C40B 30/06 (20130101)
C40B 40/04 (20130101)
C40B 50/08 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2500/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779550 Andersen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada);  BRITISH COLUMBIA CANCER AGENCY BRANCH (Vancouver, Canada)
ASSIGNEE(S) The University of British Columbia (Vancouver, Canada);  British Columbia Cancer Agency Branch (Vancouver, Canada)
INVENTOR(S) Raymond John Andersen (Vancouver, Canada);  Kunzhong Jian (Surrey, Canada);  Marianne Dorothy Sadar (West Vancouver, Canada);  Nasrin R. Mawji (Burnaby, Canada);  Carmen Adriana Banuelos (Richmond, Canada)
ABSTRACT Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1, R2, L1, L2, L3, X, a, b, c, n, and m are as defined herein, are provided. Uses of such compounds for modulating androgen receptor activity and uses as therapeutics as well as methods for treatment of subjects in need thereof, including prostate cancer are also provided.
FILED Wednesday, December 09, 2020
APPL NO 17/116070
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/09 (20130101) Original (OR) Class
A61K 31/047 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Acyclic or Carbocyclic Compounds
C07C 43/23 (20130101)
C07C 43/225 (20130101)
C07C 69/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779552 Wardell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Suzanne E. Wardell (Durham, North Carolina);  Erik R. Nelson (Champaign, Illinois);  Donald P McDonnell (Chapel Hill, North Carolina)
ABSTRACT Disclosed herein are methods of treating subjects suffering from estrogen receptor positive cancer of the brain by administering a selective estrogen receptor degrader (SERM). Also disclosed are methods of treating a cancer that is resistant to an estrogen receptor modulator by administering a SERM.
FILED Wednesday, December 22, 2021
APPL NO 17/558731
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/40 (20130101)
A61K 31/40 (20130101)
A61K 31/136 (20130101)
A61K 31/137 (20130101) Original (OR) Class
A61K 31/137 (20130101)
A61K 31/138 (20130101)
A61K 31/138 (20130101)
A61K 31/565 (20130101)
A61K 31/565 (20130101)
A61K 31/4196 (20130101)
A61K 31/4196 (20130101)
A61K 31/4535 (20130101)
A61K 31/4535 (20130101)
A61K 31/5685 (20130101)
A61K 31/5685 (20130101)
A61K 45/06 (20130101)
A61K 2121/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Acyclic or Carbocyclic Compounds
C07C 217/78 (20130101)
C07C 217/84 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779559 Nobile et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Clarissa J. Nobile (Merced, California);  Megha Gulati (Merced, California)
ABSTRACT The disclosure provides compositions comprising amino acids, individually and in combination, and methods of making the compositions and methods of using the compositions as pharmaceutically active agents to, inter alia, treat disease in animals, including humans.
FILED Friday, June 03, 2022
APPL NO 17/832040
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/133 (20130101)
A61K 31/198 (20130101) Original (OR) Class
A61K 31/401 (20130101)
A61K 31/405 (20130101)
A61K 31/661 (20130101)
A61K 31/4172 (20130101)
A61K 47/08 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
A61P 31/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779566 Tyavanagimatt et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S) SIGA TECHNOLOGIES, INC. (Corvallis, Oregon)
ASSIGNEE(S) Siga Technologies, Inc. (Corvallis, Oregon)
INVENTOR(S) Shanthakumar R. Tyavanagimatt (Sammamish, Washington);  Kris Holt (Colorado Springs, Colorado);  Ying Tan (Millbrae, California);  Melialani A. C. L. S. Anderson (Corvallis, Oregon);  Dennis E. Hruby (Albany, Oregon)
ABSTRACT The present invention is directed to a dry suspension for reconstitution containing Tecovirimat (ST-246) powder and simethicone. The dry suspension is dispersed in water to provide an aqueous pharmaceutical suspension formulation for oral administration for treating orthopoxvirus infections and/or eczema vaccinatum. The suspension formulation exhibits excellent stability and good dissolution and has an improved taste and texture.
FILED Thursday, July 14, 2022
APPL NO 17/864909
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/16 (20130101)
A61K 9/0053 (20130101)
A61K 9/0095 (20130101)
A61K 31/403 (20130101) Original (OR) Class
A61K 47/26 (20130101)
A61K 47/34 (20130101)
A61K 47/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779570 Tang et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, Inc. (Tallahassee, Florida);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Hengli Tang (Tallahassee, Florida);  Emily M. Lee (Tallahassee, Florida);  Wei Zheng (Rockville, Maryland);  Ruili Huang (Rockville, Maryland);  Miao Xu (Rockville, Maryland);  Wenwei Huang (Rockville, Maryland);  Khalida Shamim (Rockville, Maryland);  Guoli Ming (Philadelphia, Pennsylvania);  Hongjun Song (Philadelphia, Pennsylvania)
ABSTRACT The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections.
FILED Tuesday, June 28, 2022
APPL NO 17/809345
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/165 (20130101)
A61K 31/245 (20130101)
A61K 31/336 (20130101)
A61K 31/352 (20130101)
A61K 31/422 (20130101)
A61K 31/427 (20130101)
A61K 31/433 (20130101)
A61K 31/506 (20130101)
A61K 31/517 (20130101)
A61K 31/519 (20130101)
A61K 31/554 (20130101)
A61K 31/4162 (20130101)
A61K 31/4184 (20130101) Original (OR) Class
A61K 31/4535 (20130101)
A61K 31/4709 (20130101)
A61K 31/4741 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779601 Bot et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Kite Pharma, Inc. (Santa Monica, California);  United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland)
ASSIGNEE(S) Kite Pharma, Inc. (Santa Monica, California);  The United States of America as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Adrian Bot (Santa Monica, California);  Jeffrey S. Wiezorek (Santa Monica, California);  William Go (Santa Monica, California);  Rajul Jain (Santa Monica, California);  James N. Kochenderfer (Bethesda, Maryland);  Steven A. Rosenberg (Bethesda, Maryland)
ABSTRACT The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes methods of identifying a patient who would respond well to a T cell therapy or conditioning a patient prior to a T cell therapy so that the patient responds well to a T cell therapy. The conditioning involves administering one or more preconditioning agents prior to a T cell therapy and identifying biomarker cytokines prior to administering a T cell therapy.
FILED Friday, May 27, 2016
APPL NO 15/577672
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/52 (20130101)
A61K 31/095 (20130101)
A61K 31/445 (20130101)
A61K 31/665 (20130101)
A61K 35/17 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/00 (20130101)
C07K 14/52 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 15/00 (20130101)
C12N 15/85 (20130101)
C12N 2510/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6869 (20130101)
G01N 2333/5418 (20130101)
G01N 2333/5443 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779603 Childs et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland);  Loyola University of Chicago (Maywood, Illinois)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  Loyola University of Chicago (Maywood, Illinois)
INVENTOR(S) Richard W. Childs (Rockville, Maryland);  Michael I. Nishimura (Maywood, Illinois);  Elena A. Cherkasova (Rockville, Maryland)
ABSTRACT Disclosed herein are T cell receptors (TCRs) capable of binding an antigen expressed by renal cell carcinoma cells. In some examples, the TCRs include an α chain (such as SEQ ID NO: 2) and a β chain (such as SEQ ID NO: 3). Also disclosed herein are vectors including nucleic acids encoding the disclosed TCR α and/or β chains. Further disclosed are modified T cells expressing the TCRs. In some examples, the modified T cells are prepared by transducing T cells with a vector including nucleic acids encoding the TCR α chain and the TCR β chain. In some embodiments, methods include treating a subject with RCC, by obtaining a population of T cells, transducing the population of T cells with a vector including a nucleic acids encoding the TCR α chain and the TCR β chain, and administering a composition comprising the modified T cells to the subject.
FILED Friday, June 30, 2017
APPL NO 16/313712
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class

Peptides
C07K 14/005 (20130101)
C07K 14/4748 (20130101)
C07K 14/7051 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779634 Pearlman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Eric Pearlman (Cleveland, Ohio);  Sixto M. Leal, Jr. (Cleveland, Ohio)
ABSTRACT A method of treating a fungal infection in a subject includes topically administering to the subject a therapeutically effective amount of a fungal iron acquisition inhibitor to treat fungal infection in the subject.
FILED Tuesday, January 25, 2022
APPL NO 17/583498
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/08 (20130101)
A61K 9/0014 (20130101)
A61K 9/0048 (20130101)
A61K 31/16 (20130101)
A61K 31/22 (20130101)
A61K 31/40 (20130101)
A61K 31/69 (20130101)
A61K 31/198 (20130101)
A61K 31/366 (20130101)
A61K 31/426 (20130101)
A61K 31/4196 (20130101)
A61K 31/4412 (20130101)
A61K 38/16 (20130101)
A61K 38/40 (20130101) Original (OR) Class
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779643 Minar
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S) Children's Hospital Medical Center (Cincinnati, Ohio)
INVENTOR(S) Phillip Minar (Montgomery, Ohio)
ABSTRACT Disclosed herein are methods for the treatment of an individual having an inflammatory bowel disease (“IBD”). The disclosed methods may include the detection of Oncostatin M (OSM) in a biological sample obtained from an individual having an IBD. The detection of OSM may be used to characterize the individual as a tumor necrosis factor (TNF) inhibitor (TNFi) responder or a TNFi non-responder for selection of appropriate treatment.
FILED Thursday, August 27, 2020
APPL NO 17/004555
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/573 (20130101)
A61K 39/39558 (20130101) Original (OR) Class
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/00 (20180101)

Peptides
C07K 16/241 (20130101)
C07K 2317/24 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6863 (20130101)
G01N 2333/52 (20130101)
G01N 2800/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779651 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Sanofi (Paris, France)
ASSIGNEE(S) Sanofi (Paris, France)
INVENTOR(S) Zhi-Yong Yang (Bridgewater, New Jersey);  Gary J. Nabel (Bridgewater, New Jersey);  Ling Xu (Bridgewater, New Jersey);  Jochen Beninga (Frankfurt am Main, Germany);  Jochen Kruip (Erzhausen, Germany);  Ercole Rao (Morfelden-Walldorf, Germany);  Wulf Dirk Leuschner (Frankfurt am Main, Germany);  Christian Beil (Frankfurt am Main, Germany);  Christian Lange (Frankfurt am Main, Germany)
ABSTRACT Provided herein are bivalent, bispecific binding proteins that specifically bind to two different HIV-1 Env protein epitopes.
FILED Tuesday, August 17, 2021
APPL NO 17/404908
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 47/6881 (20170801) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)

Peptides
C07K 16/468 (20130101)
C07K 16/1063 (20130101)
C07K 2317/31 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/94 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779653 Meng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Huan Meng (Los Angeles, California);  Melissa J. Spencer (Los Angeles, California);  April D. Pyle (Los Angeles, California);  Courtney S. Young (Los Angeles, California);  Xiangsheng Liu (Los Angeles, California);  Ying Ji (Los Angeles, California);  Michael Reza Emami (Los Angeles, California)
ABSTRACT In various embodiments a polyrotaxane carrier for in vivo delivery of a nucleic acid is provided. In certain embodiments the carrier comprises: a multi-arm polyethylene glycol (PEG) backbone comprising at least three arms; at least one cyclic compound having a cavity, where an arm of said multi-arm PEG backbone is threaded into the cavity of said cyclic compound forming an inclusion complex; a bulky moiety capping the terminal of the arm(s) threaded into said cyclic compound where said moiety inhibits dethreading of the cyclodextrin from the arm(s) of said backbone; and where at least one arm of said PEG backbone is free of cyclic compounds; and where said carrier has a net positive charge.
FILED Thursday, September 27, 2018
APPL NO 16/648204
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/60 (20170801)
A61K 47/6951 (20170801) Original (OR) Class
A61K 48/0008 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Polysaccharides; Derivatives Thereof
C08B 37/0015 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 83/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779661 Sosnovik et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) David Sosnovik (Newton, Massachusetts);  Lee Josephson (Reading, Massachusetts);  Howard Chen (Milton, Massachusetts)
ABSTRACT The present disclosure provides nucleic acid binding nanoprobes having one or more fluorochromes and a polymer, where each of the fluorochromes is connected to the polymer, and methods of using the same.
FILED Wednesday, November 08, 2017
APPL NO 16/348572
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/61 (20170801)
A61K 47/6929 (20170801)
A61K 49/10 (20130101)
A61K 49/0021 (20130101)
A61K 49/0032 (20130101)
A61K 49/0052 (20130101)
A61K 49/0054 (20130101) Original (OR) Class
A61K 51/0491 (20130101)
A61K 51/0497 (20130101)

Heterocyclic Compounds
C07D 221/12 (20130101)
C07D 413/06 (20130101)
C07D 417/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779662 Reshetnyak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island);  Yale University (New Haven, Connecticut)
ASSIGNEE(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island);  Yale University (New Haven, Connecticut)
INVENTOR(S) Yana K. Reshetnyak (South Kingstown, Rhode Island);  Oleg A. Andreev (South Kingstown, Rhode Island);  Donald M. Engelman (New Haven, Connecticut)
ABSTRACT The present subject matter provides compounds, compositions, and methods for identifying, monitoring, treating, and removing diseased tissue. Compounds, compositions, and methods for identifying, monitoring, and detecting circulating fluids such as blood are also provided.
FILED Friday, September 22, 2017
APPL NO 15/713324
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0071 (20130101)
A61B 5/0082 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/04 (20130101)
A61K 49/0034 (20130101)
A61K 49/0056 (20130101) Original (OR) Class
A61K 49/221 (20130101)
A61K 49/227 (20130101)

Peptides
C07K 14/001 (20130101)
C07K 19/00 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 69/107 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 2211/1466 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779665 Sadeghi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Saman Sadeghi (Los Angeles, California);  Mehrdad Balandeh (Los Angeles, California)
ABSTRACT Provided herein are methods of fluorinating organic compounds. The electrochemical fluorination and radiofluorination of organic molecules using the cation pool technique is described, where the 18F and/or 19F-fluorine ions are added after the process of electrochemical oxidation, i.e., after formation of a carbocationic organic compound (i.e., a compound having a carbon atom with a positive charge).
FILED Monday, February 04, 2019
APPL NO 16/963463
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/04 (20130101) Original (OR) Class

General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/001 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 3/23 (20210101)
C25B 9/23 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779762 Bhadra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Niloy Bhadra (Cleveland, Ohio);  Narendra Bhadra (Cleveland, Ohio);  Kevin L. Kilgore (Cleveland, Ohio);  Scott Lempka (Cleveland, Ohio);  Jesse Wainright (Cleveland, Ohio);  Tina Vrabec (Cleveland, Ohio);  Manfred Franke (Cleveland, Ohio)
ABSTRACT One aspect of the present disclosure is a system including a waveform generator, a controller, and an electrical contact. The waveform generator is for generating an electrical nerve conduction block (ENCB). The controller is coupled with the waveform generator. The controller is configured to receive an input comprising at least one parameter to adjust the ENCB. The electrical contact is coupled with the waveform generator. The electrical contact is configured to be placed into contact with a nerve. The electrical contact comprises a high charge capacity material that prevents formation of damaging electro-chemical products at a charge delivered by the ENCB. The electrical contact is configured to deliver the ENCB to the nerve to block transmission of a signal related to a pain through the nerve.
FILED Thursday, December 10, 2020
APPL NO 17/117228
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/06 (20130101)
A61N 1/20 (20130101)
A61N 1/0551 (20130101)
A61N 1/36021 (20130101)
A61N 1/36057 (20130101)
A61N 1/36071 (20130101) Original (OR) Class
A61N 1/36103 (20130101)
A61N 1/36125 (20130101)
A61N 1/36171 (20130101)
A61N 1/36175 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779778 Friedman
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Integrated Sensors, LLC (Ottawa Hills, Ohio)
ASSIGNEE(S) Integrated Sensors, LLC (Palm Beach Gardens, Florida)
INVENTOR(S) Peter S. Friedman (Ottawa Hills, Ohio)
ABSTRACT Embodiments are directed generally to an ionizing-radiation beamline monitoring system that includes a vacuum chamber structure with vacuum compatible flanges through which an incident ionizing-radiation beam enters the monitoring system. Embodiments further include at least one scintillator within the vacuum chamber structure that can be at least partially translated in the ionizing-radiation beam while oriented at an angle greater than 10 degrees to a normal of the incident ionizing-radiation beam, a machine vision camera coupled to a light-tight structure at atmospheric/ambient pressure that is attached to the vacuum chamber structure by a flange attached to a vacuum-tight viewport window with the camera and lens optical axis oriented at an angle of less than 80 degrees with respect to a normal of the scintillator, and at least one ultraviolet (“UV”) illumination source facing the scintillator in the ionizing-radiation beam for monitoring a scintillator stability comprising scintillator radiation damage.
FILED Wednesday, October 20, 2021
APPL NO 17/451517
ART UNIT 2884 — Optics
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/00 (20130101)
A61N 5/1045 (20130101)
A61N 5/1048 (20130101)
A61N 5/1049 (20130101)
A61N 5/1064 (20130101)
A61N 5/1067 (20130101) Original (OR) Class
A61N 5/1077 (20130101)
A61N 2005/1059 (20130101)
A61N 2005/1087 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/29 (20130101)
G01T 1/40 (20130101)
G01T 1/1612 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779922 Schwartz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin);  University of Leiden (Leiden, Netherlands);  University of Chicago (Chicago, Illinois)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) David Charles Schwartz (Madison, Wisconsin);  Kristy L. Kounovsky-Shafer (Kearney, Nebraska);  Juan Pablo Hernandez-Ortiz (Madison, Wisconsin);  Konstantinos Dimitrios Potamousis (Madison, Wisconsin);  Juan Jose De Pablo (Chicago, Illinois);  Theo Odijk (Leiden, Netherlands);  Kyubong Jo (Seoul, South Korea)
ABSTRACT Devices, systems, and methods for en masse patterning of nucleic acid molecule structures are disclosed. The devices can include microchannels and nanoslits. The microchannels and nanoslits can be connected by parking chambers. The systems and methods can utilize the geometry of the devices in coordination with a voltage application routine to park nucleic acid molecules in the parking chambers and subsequently inject the nucleic acid molecules into the nanoslits. The methods can be utilized to present nucleic acid molecules in a fashion suitable for genomic analysis. The methods can also be utilized to provide size selection of the nucleic acid molecules.
FILED Monday, December 20, 2021
APPL NO 17/556100
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101) Original (OR) Class
B01L 2200/0663 (20130101)
B01L 2300/0645 (20130101)
B01L 2300/0896 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44791 (20130101)
G01N 33/48721 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780815 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) City of Hope (Duarte, California);  California Institute of Technology (Pasadena, California)
ASSIGNEE(S) City of Hope (Duarte, California);  California Institute of Technology (Pasadena, California)
INVENTOR(S) Binghui Shen (La Verne, California);  Judith Campbell (Pasadena, California);  Li Zheng (Arcadia, California);  Hongzhi Li (Duarte, California);  David Horne (Duarte, California);  Jun Xie (Duarte, California);  Kenneth Karanja (Maple Grove, Minnesota)
ABSTRACT Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.
FILED Friday, October 29, 2021
APPL NO 17/515252
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 215/56 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780828 Georg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Ingrid Gunda Georg (Minneapolis, Minnesota);  Narsihmulu Cheryala (Minneapolis, Minnesota)
ABSTRACT The invention provides a compound of formula (I):
or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof, wherein R1-R6 have any of the values described in the specification, as well as compositions comprising a compound of formula (I). The compounds are useful as contraceptive agents.
FILED Tuesday, May 03, 2022
APPL NO 17/735918
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 15/16 (20180101)

Heterocyclic Compounds
C07D 405/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780872 Boons et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) Geert-Jan Boons (Athens, Georgia);  Anthony Robert Prudden (Athens, Georgia);  Lin Liu (Athens, Georgia)
ABSTRACT Disclosed herein are oligosaccharides and intermediates useful for the production thereof. The compounds are useful as analytical standards and as intermediates for the preparation of more complex oligosaccharide and N-glycan products. The compounds may be prepared in high purity using the selective stop/go synthetic methods disclosed herein.
FILED Wednesday, December 09, 2020
APPL NO 17/116706
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 5/06 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/26 (20130101)
C12P 19/305 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780885 Dowd et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
INVENTOR(S) Kimberly Dowd (Rockville, Maryland);  Barney S. Graham (Rockville, Maryland);  Sung-Youl Ko (Rockville, Maryland);  Wing-Pui Kong (Rockville, Maryland);  John Mascola (Rockville, Maryland);  Theodore Pierson (Rockville, Maryland);  Mayuri Sharma (Cambridge, Massachusetts);  Dong Yu (Rockville, Maryland)
ABSTRACT Compounds useful as components of immunogenic compositions for the induction of an immunogenic response in a subject against viral infection, methods for their use in treatment, and processes for their manufacture are provided herein. The compounds comprise a nucleic acid construct comprising a sequence which encodes a Zika virus antigen.
FILED Wednesday, November 15, 2017
APPL NO 16/461503
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 2039/53 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/24122 (20130101)
C12N 2770/24134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780896 Horowitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Colorado Seminary Which Owns and Operates the University of Denver (Denver, Colorado)
ASSIGNEE(S) University of Denver (Denver, Colorado)
INVENTOR(S) Scott Horowitz (Englewood, Colorado);  Adam Begeman (Denver, Colorado);  Ahhyun Son (Denver, Colorado);  Alexa Gomez (Thornton, Colorado);  Theodore Litberg (Denver, Colorado)
ABSTRACT Systems and method for providing chaperone activity to a protein-containing compound is disclosed. The method includes selecting a nucleic acid based on one or more of the nucleic acid's particular properties and a specific sequence of the nucleic acid and applying the nucleic acid to a compound comprising one or more proteins to provide chaperone activity to the compound.
FILED Monday, November 16, 2020
APPL NO 17/098571
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/4702 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 2310/151 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6839 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780901 Gellman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Samuel H. Gellman (Madison, Wisconsin);  Shi Liu (Madison, Wisconsin);  Thomas J. Gardella (Needham, Massachusetts)
ABSTRACT Described are polypeptide analogs of parathyroid hormone (PTH) that include an unnatural amino acid substitution at positions 7 or 8 from the N-terminus of the polypeptide. Also described are pharmaceutical compositions useful for treating hypoparathyroidism that contain the analogs and methods of using the analogs to treat hypoparathyroidism.
FILED Thursday, September 24, 2020
APPL NO 17/031178
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/635 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780918 Majeti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Ravindra Majeti (Palo Alto, California);  Irving L. Weissman (Stanford, California);  Siddhartha Jaiswal (San Francisco, California);  Mark P. Chao (Mountain View, California)
ABSTRACT Markers of acute myeloid leukemia stem cells (AMLSC) are identified. The markers are differentially expressed in comparison with normal counterpart cells, and are useful as diagnostic and therapeutic targets.
FILED Wednesday, May 04, 2022
APPL NO 17/736847
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)
A61K 2039/507 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/02 (20180101)

Peptides
C07K 16/28 (20130101)
C07K 16/30 (20130101)
C07K 16/2803 (20130101) Original (OR) Class
C07K 16/2896 (20130101)
C07K 2317/24 (20130101)
C07K 2317/73 (20130101)
C07K 2317/75 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0093 (20130101)
C12N 5/0694 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/112 (20130101)
C12Q 2600/136 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5011 (20130101)
G01N 33/57426 (20130101)
G01N 2500/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780931 Weiskopf et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Kipp Andrew Weiskopf (Brookline, Massachusetts);  Kim J. Hasenkrug (Victor, Montana);  Cheryl A. Stoddart (Pacifica, California);  Joseph McCrary McCune (San Francisco, California);  Irving L. Weissman (Stanford, California)
ABSTRACT Methods are provided for treating a subject with for an intracellular pathogen infection, by administering an agent that reduces the binding of CD47 on a infected cell to SIRPα on a host phagocytic cell, in an effective dose for increasing the phagocytosis of infected cells.
FILED Tuesday, December 14, 2021
APPL NO 17/550881
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1774 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/2803 (20130101)
C07K 16/2896 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/76 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780932 Zorniak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Michael Zorniak (San Diego, California);  Paul A. Clark (Madison, Wisconsin);  Yongku Peter Cho (Storrs, Connecticut);  Benjamin J. Umlauf (Madison, Wisconsin);  Eric V. Shusta (Madison, Wisconsin);  John Shu-Shin Kuo (Austin, Texas)
ABSTRACT The present invention provides antibodies that target glioblastoma stem-like cells and methods and kits for their use.
FILED Tuesday, October 09, 2018
APPL NO 16/754677
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0058 (20130101)
A61K 2039/505 (20130101)

Peptides
C07K 16/3053 (20130101) Original (OR) Class
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57407 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780982 Turng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Lih-Sheng Turng (Madison, Wisconsin);  Yiyang Xu (Madison, Wisconsin);  Yu-Jyun Lin (Madison, Wisconsin);  Dong-Fang Wang (Madison, Wisconsin)
ABSTRACT Green, fast and easy evaporating organic solvent for use as a lubricant in the processing of polytetrafluoroethylene (PTFE) and expanded polytetrafluoroethylene (ePTFE) products and processes of using the solvents to fabricate the products are disclosed herein. The products can be used in the field of bio- and medical applications, such as for use in vascular grafts, cardiovascular and soft tissue patches, facial implants, surgical sutures, and endovascular prosthesis, and for any products known in the aerospace, electronics, fabrics, filtration, industrial and sealant arts.
FILED Monday, April 25, 2022
APPL NO 17/728188
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/16 (20130101)
A61L 27/56 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/092 (20130101)
C08J 9/286 (20130101) Original (OR) Class
C08J 2201/03 (20130101)
C08J 2201/0502 (20130101)
C08J 2327/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780984 Kendall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Eric L. Kendall (College Park, Maryland);  Erik Wienhold (College Park, Maryland);  Omid Rahmanian (College Park, Maryland);  Don L. Devoe (College Park, Maryland)
ABSTRACT Bare porous polymer monoliths, fluidic chips, methods of incorporating bare porous polymer monoliths into fluidic chips, and methods for functionalizing bare porous polymer monoliths are described. Bare porous polymer monoliths may be fabricated ex situ in a mold. The bare porous polymer monoliths may also be functionalized ex situ. Incorporating the bare preformed porous polymer monoliths into the fluidic chips may include inserting the monoliths into channels of channel substrates of the fluidic chips. Incorporating the bare preformed porous polymer monoliths into the fluidic chips may include bonding a capping layer to the channel substrate. The bare porous polymer monoliths may be mechanically anchored to channel walls and to the capping layer. The bare porous polymer monoliths may be functionalized by ex situ immobilization of capture probes on the monoliths. The monoliths may be functionalized by direct attachment of chitosan.
FILED Monday, June 08, 2020
APPL NO 16/895617
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Separation
B01D 2253/342 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/2485 (20130101)
B01J 20/3007 (20130101)
B01J 20/3242 (20130101)
B01J 20/3255 (20130101)
B01J 2219/2402 (20130101)
B01J 2219/2433 (20130101)
B01J 2220/82 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502 (20130101)
B01L 3/5023 (20130101)
B01L 3/502707 (20130101)
B01L 3/502723 (20130101)
B01L 3/502753 (20130101)
B01L 2200/12 (20130101)
B01L 2200/0631 (20130101)
B01L 2300/16 (20130101)
B01L 2300/165 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/325 (20200201)
C08F 222/102 (20200201)
C08F 222/103 (20200201)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/246 (20130101)
C08J 9/36 (20130101) Original (OR) Class
C08J 9/224 (20130101)
C08J 9/286 (20130101)
C08J 2201/026 (20130101)
C08J 2205/022 (20130101)
C08J 2205/024 (20130101)
C08J 2207/00 (20130101)
C08J 2333/10 (20130101)
C08J 2333/14 (20130101)
C08J 2335/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781035 Taton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Innovative Surface Technologies, Inc. (St. Paul, Minnesota)
ASSIGNEE(S) Innovative Surface Technologies, Inc. (St. Paul, Minnesota)
INVENTOR(S) Kristin Taton (Little Canada, Minnesota);  Daniel Guire (Hopkins, Minnesota);  Nathaniel Olson (Minneapolis, Minnesota);  Eric Guire (St. Paul, Minnesota);  Patrick Guire (Hopkins, Minnesota)
ABSTRACT Durable polyurea copolymer coatings can be applied to surfaces that come in contact with fluids, such as biological fluids, thereby passivating the surface. Polyurea copolymer coating compositions comprise a reaction product of (a) a diamine composition that includes a polyethylene glycol diamine, and optionally, a dipiperidyl alkane; and (b) a diisocyanate. Solutions containing polyurea copolymers, coated surfaces and methods are also described.
FILED Tuesday, December 11, 2018
APPL NO 16/771285
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/6846 (20130101)

Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/02 (20130101)
B05D 1/18 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/73 (20130101)
C08G 18/325 (20130101)
C08G 18/755 (20130101)
C08G 18/3228 (20130101)
C08G 18/5024 (20130101)
C08G 18/6685 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/1662 (20130101)
C09D 175/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781101 Panoskaltsis-Mortari et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Angela Panoskaltsis-Mortari (Woodbury, Minnesota);  Michael C. McAlpine (Minneapolis, Minnesota);  Fanben Meng (Saint Paul, Minnesota)
ABSTRACT A 3D-printed in vitro model biological microenvironment in examples discussed below may have one or more of the following features: (a) a gel matrix 3D-printed scaffold, wherein the gel matrix comprises a chemical composition configured to culture a first type of live cells, (b) a target chemical disposed at one or more locations within the gel matrix, the target chemical forming a chemical depot from which a chemical gradient is created within the gel matrix, (c) a conduit disposed within the gel matrix and defining a lumen comprising a second type of live cells, wherein the conduit is configured to enable at least some of the first type of live cells to migrate through the conduit and facilitate flow of at least: some of the live cells to an outlet of the conduit, or enable introduction of at least one of other cells, Achemical mediators, or drugs into the 3D-printed microenvironment.
FILED Tuesday, November 05, 2019
APPL NO 16/674815
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/4825 (20130101)
A61K 9/4833 (20130101)
A61K 9/4866 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/00 (20210101)
B22F 10/85 (20210101)
B22F 12/00 (20210101)
B22F 12/82 (20210101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/00 (20170801)
B29C 64/10 (20170801)
B29C 64/20 (20170801)
B29C 64/25 (20170801)
B29C 64/30 (20170801)
B29C 64/40 (20170801)
B29C 64/176 (20170801)
B29C 64/182 (20170801)
B29C 64/205 (20170801)
B29C 64/227 (20170801)
B29C 64/245 (20170801)
B29C 64/255 (20170801)
B29C 64/307 (20170801)
B29C 64/386 (20170801)
B29C 64/393 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 40/00 (20141201)
B33Y 40/10 (20200101)
B33Y 40/20 (20200101)
B33Y 50/00 (20141201)
B33Y 50/02 (20141201)
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)
B33Y 99/00 (20141201)

Apparatus for Enzymology or Microbiology;
C12M 25/14 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0691 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/4833 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781135 Miller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Washington University (St. Louis, Missouri);  Biogen MA Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) Washington University (St. Louis, Missouri);  Biogen MA Inc. (Cambridge, Massachusetts)
INVENTOR(S) Timothy M. Miller (St. Louis, Missouri);  Sarah Devos (St. Louis, Missouri);  C. Frank Bennett (Carlsbad, California);  Frank Rigo (Carlsbad, California)
ABSTRACT Disclosed herein are methods for reducing expression of Tau mRNA and protein in an animal with Tau antisense compounds. Also disclosed are methods for modulating splicing of Tau mRNA in an animal with Tau antisense compounds. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. Examples of neurodegenerative diseases that can be treated, prevented, and ameliorated with the administration Tau antisense oligonucleotides include Alzheimer's Disease, Fronto-temporal Dementia (FTD), FTDP-17, Progressive Supranuclear Palsy, Chronic Traumatic Encephalopathy, Epilepsy, and Dravet's Syndrome.
FILED Monday, March 11, 2019
APPL NO 16/298607
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/321 (20130101)
C12N 2310/341 (20130101)
C12N 2310/346 (20130101)
C12N 2310/3341 (20130101)
C12N 2310/3525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781144 Arora
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Rishi Arora (Chicago, Illinois)
ABSTRACT Disclosed herein are pharmaceutical compositions and methods for inhibiting oxidative stress in a subject having atrial or ventricular arrhythmias, ventricular failure or heart failure. The methods include administering an effective amount of a NOX2 inhibitor agent to the subject, wherein said administering is under conditions such that a level of oxidative stress in myocardial tissue is reduced or eliminated. The pharmaceutical compositions include a NOX2 inhibitor agent.
FILED Monday, April 26, 2021
APPL NO 17/240659
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/316 (20210101)
A61B 5/361 (20210101)
A61B 5/4848 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1137 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/531 (20130101)

Enzymes
C12Y 106/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781172 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts);  PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Feng Zhang (Cambridge, Massachusetts);  Bernd Zetsche (Gloucester, Massachusetts);  Jonathan S. Gootenberg (Cambridge, Massachusetts);  Omar O. Abudayyeh (Boston, Massachusetts);  Ian Slaymaker (Cambridge, Massachusetts)
ABSTRACT The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a novel DNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA. Methods for making and using and uses of such systems, methods, and compositions and products from such methods and uses are also disclosed and claimed.
FILED Tuesday, April 30, 2019
APPL NO 16/400026
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/113 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101)
C12Q 1/6816 (20130101)
C12Q 1/6832 (20130101) Original (OR) Class
C12Q 2521/301 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781173 Singer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York)
ASSIGNEE(S) Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S) Robert H. Singer (New York, New York);  Evelina Tutucci (New York, New York);  Maria Vera Ugalde (New York, New York)
ABSTRACT An RNA tagging system for visualization of single mRNA molecules based on a MSB-MCP system, as well as methods of use.
FILED Thursday, April 19, 2018
APPL NO 16/606046
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6841 (20130101) Original (OR) Class
C12Q 1/6897 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781179 Iafrate et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
INVENTOR(S) Anthony John Iafrate (Newton, Massachusetts);  Long Phi Le (Boston, Massachusetts);  Zongli Zheng (Boston, Massachusetts)
ABSTRACT The technology described herein is directed to methods of determining oligonucleotide sequences, e.g. by enriching target sequences prior to sequencing the sequences.
FILED Wednesday, June 10, 2020
APPL NO 16/897588
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6855 (20130101) Original (OR) Class
C12Q 1/6855 (20130101)
C12Q 1/6874 (20130101)
C12Q 2525/155 (20130101)
C12Q 2525/161 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/191 (20130101)
C12Q 2531/113 (20130101)
C12Q 2535/122 (20130101)
C12Q 2535/122 (20130101)
C12Q 2537/159 (20130101)
C12Q 2537/159 (20130101)
C12Q 2549/119 (20130101)
C12Q 2565/607 (20130101)
C12Q 2565/607 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781188 De Vlaminck et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Iwijn De Vlaminck (Ithaca, New York);  John Richard Lee (Ithaca, New York);  Philip Smith Burnham (Ithaca, New York);  Alexandre Pellan Cheng (Ithaca, New York);  Manikkam Suthanthrian (Ithaca, New York);  Darshana Dadhania (Ithaca, New York)
ABSTRACT The present disclosure is directed to methods of detecting cell-free DNA (cfDNA) in biological samples and using it to quantify organ damage and identify pathogens. In some aspects, the biological samples are from patients who have undergone solid-organ transplantation. The disclosure is also directed to methods of detecting and analyzing methylation patterns in cell-free DNA from organ transplant patients to identify the presence of pathogens as well as quantify contributing tissue proportions as a measurement of the host response.
FILED Thursday, April 05, 2018
APPL NO 16/500929
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101)
C12Q 1/701 (20130101)
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/154 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 30/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781193 Shalek et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Alexander K. Shalek (Cambridge, Massachusetts);  Carly Ziegler (Cambridge, Massachusetts)
ABSTRACT Embodiments disclosed herein provide a pan-tissue cell atlas of healthy and diseased subjects obtained by single cell sequencing. The present invention discloses novel markers for cell types. Moreover, genes associated with disease, including HIV infection and tuberculosis are identified. The invention provides for diagnostic assays based on gene markers and cell composition, as well as therapeutic targets for controlling immune regulations and cell-cell communication of the cell types disclosed herein. In addition, novel cell types and methods of quantitating, detecting and isolating the cell types are disclosed.
FILED Tuesday, October 16, 2018
APPL NO 16/756573
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/703 (20130101) Original (OR) Class
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781955 Kobayashi et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Hisataka Kobayashi (Laurel, Maryland);  Peter Choyke (Rockville, Maryland);  Martin John Schnermann (Rockville, Maryland)
ABSTRACT This disclosure provides IR700-molecule conjugates and methods of their use to remove (e.g., separate or isolate) a target from a sample in vivo or from a subject in vitro. It is shown herein that exposure of IR700 to near infrared (NIR) light removes a portion of IR700, changing it from a hydrophilic molecule, to one that is hydrophobic, resulting in aggregation of IR700 and anything bound to it. For example, the disclosed IR700-molecule conjugates and methods provide photo-controlled ways to control the pharmacokinetics of a drug in vivo, and can be used to remove undesired agents from environmental or food samples or to isolate target molecules in a laboratory.
FILED Monday, September 21, 2020
APPL NO 17/026724
ART UNIT 1678 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0071 (20130101)
A61K 47/6891 (20170801)
A61K 49/0036 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101)
A61N 2005/0651 (20130101)
A61N 2005/0663 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/44 (20130101) Original (OR) Class
G01N 1/405 (20130101)
G01N 33/5002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782011 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Morgan State University (Baltimore, Maryland)
ASSIGNEE(S) MORGAN STATE UNIVERSITY (Baltimore, Maryland)
INVENTOR(S) Yongchao Zhang (Ellicott City, Maryland);  Aeshah Alshehri (Tanomah, Saudi Arabia)
ABSTRACT An electrochemical biosensor includes a working electrode modified with a redox polymer and amine-terminated capture aptamer specific for a particular detection target. The binding sequence of the capture aptamer is also complementary to part of a second ssDNA which is labeled with HRP (horseradish peroxidase). The capture aptamer will form dsDNA with the HRP-labeled ssDNA and bring HRP into electrical contact with the redox polymer and the electrode. Prior to capturing the detection target, addition of H2O2 will lead to the highest reduction current due to the redox polymer-mediated, enzyme-amplified electroreduction of H2O2.
FILED Wednesday, April 28, 2021
APPL NO 17/243107
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3276 (20130101)
G01N 27/3277 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782046 Chiou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Pei-Yu E. Chiou (Los Angeles, California);  Michael A. Teitell (Tarzana, California);  Xiongfeng Zhu (Los Angeles, California);  Xing Haw Marvin Tan (Jurong West, Singapore);  Thang Nguyen (Fountain Valley, California)
ABSTRACT New platform technologies to actuate and sense force propagation in real-time for large sheets of cells are provided. In certain embodiments the platform comprises a device for the measurement of mechanical properties of cells or other moieties, where device comprises a transparent elastic or viscoelastic polymer substrate disposed on a rigid transparent surface; and a plurality of micromirrors disposed on or in said polymer substrate, wherein the reflective surfaces of the micromirrors are oriented substantially parallel to the surface of said polymer substrate. In certain embodiments the device comprises more than about 1,000,000, or more than about 10,000,000 micromirrors. In certain embodiments the micromirrors comprise a magnetic layer and/or a diffraction grating.
FILED Tuesday, July 03, 2018
APPL NO 16/626507
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 5/266 (20130101)
G01D 5/285 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/4833 (20130101) Original (OR) Class
G01N 33/5008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782064 Linghu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Changyang Linghu (Cambridge, Massachusetts);  Shannon L. Johnson (Cambridge, Massachusetts);  Edward Stuart Boyden (Chestnut Hill, Massachusetts)
ABSTRACT The invention, in some aspects, relates to the preparation and use of signaling reporter islands (SiRIs) in single cells. Compositions of the invention that produce SiRIs can be delivered to a cell resulting in the presence of one or more SiRIs in the cell. Methods of the invention include detecting signals generated by elements in the SiRIs in a cell and use of the detected signals to determine and analyze simultaneous physiological processes within the cell, or cells.
FILED Monday, September 14, 2020
APPL NO 17/020803
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/705 (20130101)
C07K 2319/01 (20130101)
C07K 2319/60 (20130101)
C07K 2319/735 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/10 (20130101)
C12N 15/62 (20130101)
C12N 15/63 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
G01N 33/5005 (20130101)
G01N 33/6872 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782065 Tarca et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Wayne State University (Detroit, Michigan);  The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) Wayne State University (Detroit, Michigan);  The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Adi L. Tarca (South Lyon, Michigan);  Piya Chaemsaithong (Shatin, China Hong Kong);  Tinnakorn Chaiworapongsa (Grosse Pointe Park, Michigan);  Sonia S. Hassan (Novi, Michigan);  Roberto Romero (Grosse Pointe, Michigan)
ABSTRACT Biomarkers tests which can be used to predict a positive or negative risk of preeclampsia are described. More specifically, a panel of biomarkers including MMP-7 and gpIIbIIIa, described. The test is useful to predict preeclampsia when a biological sample is obtained between the 16th and 22nd week of pregnancy. Prediction later in pregnancy can be achieved by a combination of Siglec-6, Activin A, ALCAM, and/or FCN2.
FILED Tuesday, December 21, 2021
APPL NO 17/558248
ART UNIT 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/16 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/158 (20130101)

Enzymes
C12Y 304/24007 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/689 (20130101) Original (OR) Class
G01N 2333/96494 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782112 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Cornell University Center for Technology Licensing (CTL) (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Yi Wang (New York, New York);  Zhe Liu (New York, New York);  Jinwei Zhang (New York, New York);  Qihao Zhang (New York, New York);  Junghun Cho (New York, New York);  Pascal Spincemaille (New York, New York)
ABSTRACT Exemplary methods for quantitative mapping of physical properties, systems and computer-accessible medium can be provided to generate images of tissue magnetic susceptibility, transport parameters and oxygen consumption from magnetic resonance imaging data using the Bayesian inference approach, which minimizes a data fidelity term under a constraint of a structure prior knowledge. The data fidelity term is constructed directly from the magnetic resonance imaging data. The structure prior knowledge can be characterized from known anatomic images using image feature extraction operation or artificial neural network. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining physical properties associated with at least one structure.
FILED Thursday, May 28, 2020
APPL NO 17/614277
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/055 (20130101)
A61B 5/7221 (20130101)
A61B 5/7267 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5608 (20130101) Original (OR) Class
G01R 33/56536 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783912 Chabon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Jacob J. Chabon (Arvada, Colorado);  David M. Kurtz (San Carlos, California);  Maximilian Diehn (San Carlos, California);  Arash Ash Alizadeh (San Mateo, California)
ABSTRACT Processes and materials to detect cancer, transplant rejection, or fetal genetic abnormalities from a biopsy are described. In some cases, nucleic acid molecules, such as cell-free nucleic acids, can be sequenced, and the sequencing result can be utilized to detect sequences indicative of a neoplasm, transplant rejection, or fetal genetic abnormality. Detection of somatic variants occurring in phase and/or insertions and deletions (indels) can indicate the presence of cancer, transplant rejection, or fetal genetic abnormalities in a diagnostic scan, and a clinical intervention can be performed.
FILED Wednesday, April 27, 2022
APPL NO 17/661034
ART UNIT 1671 — Semiconductors/Memory
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6813 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6886 (20130101)
C12Q 2600/156 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/20 (20190201) Original (OR) Class
G16B 25/00 (20190201)
G16B 25/20 (20190201)
G16B 30/00 (20190201)
G16B 30/10 (20190201)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/60 (20180101)
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11785856 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Zi Chen (Hanover, New Hampshire);  John X. J. Zhang (Hanover, New Hampshire);  Lin Dong (Hanover, New Hampshire);  Zhe Xu (Hanover, New Hampshire)
ABSTRACT A piezoelectric energy harvester has a layered structure comprising a first electrode, a polymeric piezoelectric material, and a second electrode, the layered structure coupled to receive mechanical stress from the environment, and the first and second electrode electrically coupled to a power converter. The power converter is adapted to charge an energy storage device selected from a capacitor and a battery. The method of harvesting energy from the environment includes providing a piezoelectric device comprising a layer of a polymeric piezoelectric material disposed between a first and a second electrode; coupling mechanical stress derived from an environment to the piezoelectric device; and coupling electrical energy from the piezoelectric device.
FILED Friday, January 26, 2018
APPL NO 16/481023
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/3785 (20130101)

Electric Machines Not Otherwise Provided for
H02N 2/186 (20130101)

Electric solid-state devices not otherwise provided for
H10N 30/306 (20230201) Original (OR) Class
H10N 30/857 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE49687 Grembecka et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of The University of Michigan (Ann Arbor, Michigan);  Kura Oncology, Inc. (San Diego, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  KURA ONCOLOGY, INC. (San Diego, California)
INVENTOR(S) Jolanta Grembecka (Ann Arbor, Michigan);  Tomasz Cierpicki (Ann Arbor, Michigan);  Dmitry Borkin (Ann Arbor, Michigan);  Jonathan Pollock (Ann Arbor, Michigan);  Hongzhi Miao (Ann Arbor, Michigan);  Duxin Sun (Ann Arbor, Michigan);  Liansheng Li (San Diego, California);  Tao Wu (San Diego, California);  Jun Feng (San Diego, California);  Pingda Ren (San Diego, California);  Yi Liu (San Diego, California)
ABSTRACT The present disclosure provides compounds and methods for inhibiting the interaction of menin with its upstream or downstream signaling molecules including but not limited to MLL1, MLL2 and MLL-fusion oncoproteins. Compounds of the disclosure may be used in methods for the treatment of a wide variety of cancers and other diseases associated with one or more of MLL1, MLL2, MLL fusion proteins, and menin.
FILED Tuesday, February 02, 2021
APPL NO 17/165794
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Heterocyclic Compounds
C07D 495/04 (20130101) Original (OR) Class
C07D 519/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/5325 (20130101)
C07F 9/65583 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11779256 Schalk et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Health Research, Inc. (Menands, New York);  Albany Medical College (Albany, New York)
ASSIGNEE(S) HEALTH RESEARCH, INC. (Menands, New York);  ALBANY MEDICAL COLLEGE (Albany, New York)
INVENTOR(S) Gerwin Schalk (Glenmont, New York);  Anthony L. Ritaccio (Voorheesville, New York);  Adriana De Pesters (Coppet, Switzerland);  AmiLyn Taplin (Albany, New York)
ABSTRACT Provided is a method for mapping a neural area involved in speech processing, including applying a plurality of recording electrodes to a surface of a cortex of a human subject, presenting a plurality of auditory stimuli to the subject wherein some of the plurality of stimuli are speech sounds and others of the plurality of auditory stimuli are non-speech sounds, recording brain activity during the presenting of the plurality of auditory stimuli, and identifying one or more brain areas wherein activity changes more after presentation of speech sounds than it does after presentation of non-speech sounds, wherein the human subject does not speak during the presenting and the recording. Also provided is a method for mapping a neural area involved in speech production wherein the human subject does not speak during presenting speech stimuli and recording neural activity.
FILED Thursday, July 01, 2021
APPL NO 17/365032
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/03 (20130101) Original (OR) Class
A61B 5/4064 (20130101)
A61B 5/4094 (20130101)
A61B 2505/05 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/32 (20130101)
A61N 1/0531 (20130101)
A61N 1/36082 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/70 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779422 Zhao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Xuanhe Zhao (Allston, Massachusetts);  Yoonho Kim (Cambridge, Massachusetts)
ABSTRACT Robotic devices and methods for performing minimally invasive procedures on the vascular system, particularly cerebrovascular and endovascular neurosurgical procedures, where a submillimeter-scale continuum robotic device is configured and adapted for active steering and navigation based on external magnetic actuation. The submillimeter-scale continuum robotic device includes an elongate body having an inner core and an outer shell, where the outer shell is fabricated of an elastomeric material having a plurality of ferromagnetic particles dispersed therein.
FILED Thursday, August 26, 2021
APPL NO 17/458114
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/203 (20130101)
A61B 34/20 (20160201)
A61B 34/30 (20160201)
A61B 34/71 (20160201)
A61B 34/73 (20160201) Original (OR) Class
A61B 2018/00577 (20130101)
A61B 2034/731 (20160201)
A61B 2034/2061 (20160201)
A61B 2090/306 (20160201)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1682 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779476 Evans et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S) DEKA Products Limited Partnership (Manchester, New Hampshire)
ASSIGNEE(S) DEKA Products Limited Partnership (Manchester, New Hampshire)
INVENTOR(S) Christopher O. Evans (Amherst, New Hampshire);  Keith D. Violette (Sandown, New Hampshire)
ABSTRACT A system for powering a prosthetic arm is disclosed. The system includes at least one internal battery located in the prosthetic arm, at least one external battery connected to the prosthetic arm, and a master controller configured to connect either the at least one internal battery or the at least one external battery to a power bus to power the prosthetic arm.
FILED Tuesday, October 11, 2022
APPL NO 17/963689
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/54 (20130101)
A61F 2/70 (20130101) Original (OR) Class
A61F 2/74 (20210801)
A61F 2/78 (20130101)
A61F 2/581 (20130101)
A61F 2/582 (20130101)
A61F 2/585 (20130101)
A61F 2/586 (20130101)
A61F 2002/587 (20130101)
A61F 2002/701 (20130101)
A61F 2002/702 (20130101)
A61F 2002/704 (20130101)
A61F 2002/705 (20130101)
A61F 2002/708 (20130101)
A61F 2002/764 (20130101)
A61F 2002/768 (20130101)
A61F 2002/769 (20130101)
A61F 2002/5001 (20130101)
A61F 2002/5061 (20130101)
A61F 2002/5083 (20130101)
A61F 2002/6836 (20130101)
A61F 2002/6845 (20130101)
A61F 2002/6881 (20130101)
A61F 2002/7625 (20130101)
A61F 2002/7635 (20130101)
A61F 2002/7645 (20130101)
A61F 2002/7665 (20130101)
A61F 2002/7862 (20130101)
A61F 2002/30462 (20130101)
A61F 2220/0075 (20130101)
A61F 2250/008 (20130101)
A61F 2250/0074 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 19/005 (20130101)

Couplings for Transmitting Rotation; Clutches; Brakes
F16D 9/06 (20130101)
F16D 27/01 (20130101)
F16D 41/12 (20130101)
F16D 41/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779601 Bot et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Kite Pharma, Inc. (Santa Monica, California);  United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland)
ASSIGNEE(S) Kite Pharma, Inc. (Santa Monica, California);  The United States of America as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Adrian Bot (Santa Monica, California);  Jeffrey S. Wiezorek (Santa Monica, California);  William Go (Santa Monica, California);  Rajul Jain (Santa Monica, California);  James N. Kochenderfer (Bethesda, Maryland);  Steven A. Rosenberg (Bethesda, Maryland)
ABSTRACT The invention provides methods of increasing the efficacy of a T cell therapy in a patient in need thereof. The invention includes methods of identifying a patient who would respond well to a T cell therapy or conditioning a patient prior to a T cell therapy so that the patient responds well to a T cell therapy. The conditioning involves administering one or more preconditioning agents prior to a T cell therapy and identifying biomarker cytokines prior to administering a T cell therapy.
FILED Friday, May 27, 2016
APPL NO 15/577672
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/52 (20130101)
A61K 31/095 (20130101)
A61K 31/445 (20130101)
A61K 31/665 (20130101)
A61K 35/17 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/00 (20130101)
C07K 14/52 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 15/00 (20130101)
C12N 15/85 (20130101)
C12N 2510/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6869 (20130101)
G01N 2333/5418 (20130101)
G01N 2333/5443 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779699 Pedroni et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Lynntech, Inc. (College Station, Texas)
ASSIGNEE(S) LYNNTECH, INC. (College Station, Texas)
INVENTOR(S) Jesse Pedroni (Castle Rock, Colorado);  Jibi Varughese (Eindhoven, Netherlands);  Grayson Ridge (Highlands Ranch, Colorado);  Graham Weeks (College Station, Texas);  Alex Moreland (College Station, Texas);  Jonathan Presley (College Station, Texas);  Jonathan A. Reeh (College Station, Texas);  Tiffany Jefferson (The Woodlands, Texas);  Seth Berry (Bryan, Texas);  Seth Cocking (Sugar Land, Texas);  Justin McIntire (College Station, Texas);  Jady Stevens (Bryan, Texas);  Chris Hadley (Bryan, Texas);  John Zbranek (College Station, Texas);  Rebecca Berger (Bryan, Texas);  Kacey G. Ortiz (College Station, Texas);  Geoffrey Duncan Hitchens (Allen, Texas);  Ashwin Balasubramanian (The Woodlands, Texas)
ABSTRACT A pump including a disposable component including a disposable component inlet port coupled to a first disposable conduit in fluid communication with a fluid medium source, wherein the first disposable conduit includes a disposable piston pump assembly and a disposable bubble eliminator, and the first disposable conduit is in fluid communication with a disposable component outlet port, wherein the disposable bubble eliminator is in fluid communication with a lumen of the first disposable conduit and is operable to reduce a gas content of a fluid medium; wherein the disposable piston pump assembly is operable to pump the fluid medium from the disposable component inlet port, through the first disposable conduit and the disposable bubble eliminator, to the disposable component outlet port; and a reusable component including a reusable movable stage operable to compress the disposable piston pump assembly; and a reusable mechanical actuator operable to drive the movable stage.
FILED Thursday, September 03, 2020
APPL NO 17/011749
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/1454 (20130101) Original (OR) Class
A61M 5/16809 (20130101)
A61M 5/16886 (20130101)
A61M 2005/5046 (20130101)
A61M 2005/14268 (20130101)
A61M 2205/505 (20130101)
A61M 2205/3334 (20130101)
A61M 2205/8206 (20130101)
A61M 2205/8262 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779901 McGill et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) R. Andrew McGill (Lorton, Virginia);  Courtney A. Roberts (Washington, District of Columbia)
ABSTRACT The invention relates to strong hydrogen-bond acidic sorbents. The sorbents may be provided in a form that limits or eliminates intramolecular bonding of the hydrogen-bond acidic site between neighboring sorbent molecules, for example, by providing steric groups adjacent to the hydrogen-bond acidic site. The hydrogen bond site may be a phenolic structure based on a bisphenol architecture. The sorbents of the invention may be used in methods for trapping or detecting hazardous chemicals or explosives.
FILED Thursday, April 21, 2022
APPL NO 17/725811
ART UNIT 1796 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/22 (20130101) Original (OR) Class
B01J 20/281 (20130101)
B01J 20/282 (20130101)
B01J 20/286 (20130101)
B01J 20/3425 (20130101)
B01J 20/3483 (20130101)
B01J 20/28023 (20130101)
B01J 2220/54 (20130101)

Acyclic or Carbocyclic Compounds
C07C 39/367 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 14/06 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 59/00 (20130101)
C08G 64/00 (20130101)
C08G 64/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780003 Wright et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) QuesTek Innovations LLC (Evanston, Illinois)
ASSIGNEE(S) QuesTek Innovations LLC (Evanston, Illinois)
INVENTOR(S) James A. Wright (Los Gatos, California);  Jason Sebastian (Chicago, Illinois);  Herng-Jeng Jou (San Jose, California);  Thomas S. Kozmel, II (Des Plaines, Illinois);  Clay A. Houser (Chicago, Illinois)
ABSTRACT Provided herein are titanium alloys that can achieve a combination of high strength and high toughness or elongation, and a method to produce the alloys. By tolerating iron, oxygen, and other incidental elements and impurities, the alloys enable the use of lower quality scrap as raw materials. The alloys are castable and can form α-phase laths in a basketweave morphology by a commercially feasible heat treatment that does not require hot-working or rapid cooling rates. The alloys comprise, by weight, about 3.0% to about 6.0% aluminum, 0% to about 1.5% tin, about 2.0% to about 4.0% vanadium, about 0.5% to about 4.5% molybdenum, about 1.0% to about 2.5% chromium, about 0.20% to about 0.55% iron, 0% to about 0.35% oxygen, 0% to about 0.007% boron, and 0% to about 0.60% other incidental elements and impurities, the balance of weight percent comprising titanium. There exists an unmet need to produce titanium alloys for use in aerospace applications which have a refined equiaxed grain structure. This can be beneficial for fatigue critical applications. The technology developed by QuesTek describes a titanium alloy and manufacturing methods thereof to obtain equiaxed grains on the order of 300 microns and corresponding UTS of approximately 170 ksi. In addition, various forms of the alloys are disclosed including ingots, billets, powders and wire in accord with the described microstructure and physical characteristics.
FILED Tuesday, November 12, 2019
APPL NO 16/681112
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 25/00 (20130101) Original (OR) Class

Alloys
C22C 1/02 (20130101)
C22C 14/00 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/183 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780014 Behera et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) QUESTEK INNOVATIONS LLC (Evanston, Illinois)
ASSIGNEE(S) QUESTEK INNOVATIONS LLC (Evanston, Illinois)
INVENTOR(S) Amit Behera (Evanston, Illinois);  Greg Olson (Evanston, Illinois)
ABSTRACT Exemplary martensitic steel alloys may be particularly suited for additive manufacturing applications. Exemplary atomized alloy powders usable in additive manufacturing may include carbon, nickel, manganese, chromium, and the balance iron and incidental impurities. Exemplary steel alloys can be molybdenum free.
FILED Friday, February 26, 2021
APPL NO 17/186556
ART UNIT 1738 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/00 (20130101)
B22F 9/08 (20130101)
B22F 10/20 (20210101) Original (OR) Class
B22F 10/28 (20210101)
B22F 10/64 (20210101)
B22F 2301/35 (20130101)
B22F 2303/01 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 70/00 (20141201)

Alloys
C22C 38/04 (20130101)
C22C 38/005 (20130101)
C22C 38/50 (20130101)
C22C 38/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780023 Paul et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) The Florida International University Board of Trustees (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Tanaji Paul (Miami, Florida);  Arvind Agarwal (Miami, Florida);  Cheng Zhang (Miami, Florida);  Sohail Mazher Ali Khan Mohammed (Miami, Florida)
ABSTRACT Methods for fabricating high-strength aluminum-boron nitride nanotube (Al—BNNT) wires or wire feedstock from Al—BNNT composite raw materials by mechanical deformation using wire drawing and extrusion are provided, as well as large-scale, high-strength Al—BNNT composite components (e.g., with a length on the order of meters (m) and/or a mass on the order of hundreds of kilograms (kg)). The large-scale, high-strength Al—BNNT composite components can be made via wire-based additive manufacturing.
FILED Wednesday, December 14, 2022
APPL NO 18/065791
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/14 (20220101)
B22F 1/107 (20220101)

Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 9/044 (20130101) Original (OR) Class
B23K 37/0229 (20130101)
B23K 2103/10 (20180801)
B23K 2103/16 (20180801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/10 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780141 Ioannidis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Nikolaos Ioannidis (Bloomfield, New Jersey);  Zohar Ophir (West Orange, New Jersey);  Viral Panchal (Parlin, New Jersey);  Philip Abbate (Hackettstown, New Jersey);  Francis Sullivan (Morristown, New Jersey);  Ming Wan Young (Basking Ridge, New Jersey);  Costas G. Gogos (Wyckoff, New Jersey)
ABSTRACT The present invention is directed to a continuous process for producing a foamable celluloid product by introducing a solid component (comprising nitrocellulose, chemical blowing agent (CBA), stabilizer and alcohol) and a liquid component (comprising camphor and acetone) into a mixer/devolatilizer machine where the chamber is under atmospheric pressure and having significant overhead space. The chamber is comprised of two zones wherein the first zone has a temperature that is less than the second zone and at least one rotor comprising hollow, temperature-controlled arms having a tilted angle affixed to the rotors. The rotors of the mixer/devolatilizer machine act to mix the solid and liquid components under lower shearing forces, lower mechanical stress and longer residence times than those used by twin-screw extruders.
FILED Tuesday, December 03, 2019
APPL NO 16/701823
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 27/702 (20220101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 48/0012 (20190201) Original (OR) Class
B29C 48/29 (20190201)
B29C 48/397 (20190201)
B29C 2948/92704 (20190201)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2001/18 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/0023 (20130101)
C08J 2301/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780154 Ware et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas);  University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Taylor H. Ware (Dallas, Texas);  Cedric P. Ambulo (Plano, Texas);  Mohand O. Saed (Dallas, Texas);  Jennifer M. Boothby (Plano, Texas);  Julia J. Henricks (Dallas, Texas);  Ravi Shankar Meenakshisundaram (Aspinwall, Pennsylvania)
ABSTRACT A method of ink-extrusion printing an object, including providing a mixture including liquid crystal monomers and photo-catalyzing or heating the mixture to produce a liquid crystal ink. The ink is in a nematic phase. The method includes extruding the ink through a print-head orifice moving along a print direction to form an extruded film of the object. The extruded film exhibits birefringence. Also disclosed are a liquid crystal ink. The ink includes a mixture including liquid crystal monomers. The mixture when at a target printing temperature is in a nematic phase. Also disclosed is ink-extrusion-printed object. The object includes an extrusion-printed film including a nematic liquid crystal elastomer, wherein the film exhibits birefringence along an extrusion axis of the film.
FILED Friday, April 23, 2021
APPL NO 17/238771
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/106 (20170801) Original (OR) Class
B29C 64/112 (20170801)
B29C 71/04 (20130101)
B29C 2035/0827 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2105/0079 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/101 (20130101)
C09D 11/107 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780574 Preiss et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
ASSIGNEE(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
INVENTOR(S) Yair Preiss (Norwalk, Connecticut);  Bradley M. Bauer (Fort Worth, Texas)
ABSTRACT A rotatable swashplate is rotatable relative to a stationary swashplate around a shaft and connects to a pitch control rod assembly. The rotatable swashplate includes an upper portion and a lower portion. The upper portion is extendable outside of a stationary swashplate and includes a plurality of lugs each configured to attach to a pitch control rod assembly, an innermost wall configured to receive a shaft, and a membrane. The lower portion is positionable within the stationary swashplate and has an outermost wall and at least one extension extending radially between the outermost wall and the innermost wall. The membrane extends radially over the at least one extension.
FILED Thursday, June 03, 2021
APPL NO 17/337719
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/10 (20130101)
B64C 27/605 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780586 Provenza
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Jerry Provenza (Niceville, Florida)
ABSTRACT An adaptive force vehicle airbag (AFVA) system includes airbag(s) stowed in a compressed state within an interior of a vehicle. An impact sensor detects a change in motion of the vehicle indicative of a collision. Selectable force gas generator(s) (SFGGs) gas-generating propellant cells that are individually fired. The SFGGs have conduit(s) that receive gas from fired gas-generating propellant cells and direct the gas to inflate at least one of the airbag(s). A controller is communicatively coupled to the inflation initiating component and the gas-generating propellant cells of the SFGGs. The controller enables the AFVA system to: (i) receive an inflation signal from the impact sensor; and (ii) fire a selected number of the gas-generating propellant cells to at least partially inflate the at least one airbag.
FILED Tuesday, September 01, 2020
APPL NO 17/009079
ART UNIT 3614 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for
B60R 21/26 (20130101)
B60R 21/0132 (20130101)
B60R 21/0136 (20130101)
B60R 21/203 (20130101)
B60R 21/207 (20130101)
B60R 21/231 (20130101)
B60R 21/01516 (20141001)
B60R 2021/0093 (20130101)
B60R 2021/01013 (20130101)
B60R 2021/01231 (20130101)
B60R 2021/2078 (20130101)
B60R 2021/23107 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 11/0621 (20141201) Original (OR) Class
B64D 2201/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780779 Apostolov
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Zlatomir D. Apostolov (Beavercreek, Ohio)
ABSTRACT The present disclosure includes a system and method for monitoring degradation of a high temperature composite component (HTC). The HTC is defined by a volume that includes a matrix material and a fiber formed from at least one of ceramic and carbon material. One or more electrical conductors are disposed within the volume and connected directly or indirectly to a monitoring system.
FILED Tuesday, April 06, 2021
APPL NO 17/223428
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/62231 (20130101)
C04B 35/62272 (20130101) Original (OR) Class
C04B 2111/94 (20130101)
C04B 2235/40 (20130101)
C04B 2235/522 (20130101)
C04B 2235/5248 (20130101)
C04B 2235/5256 (20130101)
C04B 2235/5288 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780780 Boakye et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Emmanuel E Boakye (Centerville, Ohio);  Michael K Cinibulk (Beavercreek, Ohio);  Randal S Hay (Beavercreek, Ohio);  Pavel Mogilevsky (Beavercreek, Ohio);  Triplicane A Parthasarathy (Beavercreek, Ohio);  Kristin A Keller (Springboro, Ohio)
ABSTRACT A method of manufacturing a coated reinforcing fiber for use in Ceramic Matrix Composites, the method comprising pre-oxidizing a plurality of silicon-based fibers selected from the group consisting of silicon carbide (SiC) fibers, silicon nitride (Si3N4) fibers, SiCO fibers, SiCN fibers, SiCNO fibers, and SiBCN fibers at between 700 to 1300 degrees Celsius in an oxidizing atmosphere to form a silica surface layer on the plurality of silicon-based fibers, forming a plurality of pre-oxidized fibers; applying a rare earth orthophosphate (REPO4) coating to the plurality of pre-oxidized fibers; and heating the plurality of REPO4 coated pre-oxidized fibers at about 1000-1500 degrees Celsius in an inert atmosphere to react the REPO4 with the silica surface layer to form a rare earth silicate or disilicate. The pre-oxidizing step may be 0.5 hours to about 100 hours. The heating step may be about 5 minutes to about 100 hours.
FILED Monday, March 29, 2021
APPL NO 17/214994
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/80 (20130101)
C04B 35/62675 (20130101)
C04B 35/62881 (20130101) Original (OR) Class
C04B 2235/5244 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780815 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) City of Hope (Duarte, California);  California Institute of Technology (Pasadena, California)
ASSIGNEE(S) City of Hope (Duarte, California);  California Institute of Technology (Pasadena, California)
INVENTOR(S) Binghui Shen (La Verne, California);  Judith Campbell (Pasadena, California);  Li Zheng (Arcadia, California);  Hongzhi Li (Duarte, California);  David Horne (Duarte, California);  Jun Xie (Duarte, California);  Kenneth Karanja (Maple Grove, Minnesota)
ABSTRACT Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.
FILED Friday, October 29, 2021
APPL NO 17/515252
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 215/56 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780860 Chaloux et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Brian L. Chaloux (Washington, District of Columbia);  Andrew P. Purdy (Washington, District of Columbia);  Albert Epshteyn (Washington, District of Columbia)
ABSTRACT Cyanophosphines other than P(CN)3 react with lithium dicyanamide to produce lithiated carbon phosphonitrides with mobile Li+ ions.
FILED Wednesday, November 09, 2022
APPL NO 17/983662
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/5036 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780902 Morey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado)
ASSIGNEE(S) Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S) Kevin J. Morey (Fort Collins, Colorado);  June I. Medford (Fort Collins, Colorado)
ABSTRACT The present disclosure provides compositions and methods for sensing a target substance of interest in the environment and inducing gene expression in response thereto, useful for detection of biological and chemical agents and environmental pollutants.
FILED Friday, July 19, 2019
APPL NO 16/517107
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/705 (20130101) Original (OR) Class
C07K 2319/035 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/12 (20130101)
C12N 15/62 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5097 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780984 Kendall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Eric L. Kendall (College Park, Maryland);  Erik Wienhold (College Park, Maryland);  Omid Rahmanian (College Park, Maryland);  Don L. Devoe (College Park, Maryland)
ABSTRACT Bare porous polymer monoliths, fluidic chips, methods of incorporating bare porous polymer monoliths into fluidic chips, and methods for functionalizing bare porous polymer monoliths are described. Bare porous polymer monoliths may be fabricated ex situ in a mold. The bare porous polymer monoliths may also be functionalized ex situ. Incorporating the bare preformed porous polymer monoliths into the fluidic chips may include inserting the monoliths into channels of channel substrates of the fluidic chips. Incorporating the bare preformed porous polymer monoliths into the fluidic chips may include bonding a capping layer to the channel substrate. The bare porous polymer monoliths may be mechanically anchored to channel walls and to the capping layer. The bare porous polymer monoliths may be functionalized by ex situ immobilization of capture probes on the monoliths. The monoliths may be functionalized by direct attachment of chitosan.
FILED Monday, June 08, 2020
APPL NO 16/895617
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Separation
B01D 2253/342 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/2485 (20130101)
B01J 20/3007 (20130101)
B01J 20/3242 (20130101)
B01J 20/3255 (20130101)
B01J 2219/2402 (20130101)
B01J 2219/2433 (20130101)
B01J 2220/82 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502 (20130101)
B01L 3/5023 (20130101)
B01L 3/502707 (20130101)
B01L 3/502723 (20130101)
B01L 3/502753 (20130101)
B01L 2200/12 (20130101)
B01L 2200/0631 (20130101)
B01L 2300/16 (20130101)
B01L 2300/165 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/325 (20200201)
C08F 222/102 (20200201)
C08F 222/103 (20200201)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/246 (20130101)
C08J 9/36 (20130101) Original (OR) Class
C08J 9/224 (20130101)
C08J 9/286 (20130101)
C08J 2201/026 (20130101)
C08J 2205/022 (20130101)
C08J 2205/024 (20130101)
C08J 2207/00 (20130101)
C08J 2333/10 (20130101)
C08J 2333/14 (20130101)
C08J 2335/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781106 Slocik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Joseph M Slocik (Dayton, Ohio);  Rajesh R. Naik (Centerville, Ohio);  Patrick B Dennis (Cincinnati, Ohio)
ABSTRACT A method for transfecting microorganisms comprises inoculating a growth media consisting of at least one of sterile LB media and tryptic soy broth with microorganism cells (cells) consisting of at least one of E.coli (DH5α), C. lytica, or B. subtilus, Pichia pastoris; growing the cells at between 28-40° C. to achieve a desired cell density; harvesting the cells; adding a protein ionic liquid consisting of at least one of green fluorescent protein (GFP), ferritin, rabbit IgG antibodies, and photosystem II from spinach ionic liquid to the cells; suspending the cells in the protein ionic liquid; freezing the suspended cells between −20 to −212° C.; and removing at least 99% of water from the frozen suspended cells to make a cell powder. The cell powder may be reconstituted in Tris HCl buffer and mixed to obtain uniform cell suspension; and centrifuged to obtain cell pellet.
FILED Monday, March 01, 2021
APPL NO 17/187976
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 17/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101) Original (OR) Class
C12N 9/96 (20130101)
C12N 15/87 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781149 Khalil et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Ahmad S. Khalil (Lexington, Massachusetts);  Caleb J. Bashor (Boston, Massachusetts);  Nikit Patel (Brookline, Massachusetts);  James J. Collins (Newton, Massachusetts)
ABSTRACT Embodiments disclosed herein provide artificial expression systems comprising multivalent transcription factor complexes for cooperative transcription factor assembly and modulating gene expression. More specifically, engineered synthetic transcription factors are recruited and structurally organized on synthetic gene circuits using molecular clamps, where the strength of intra-complex interactions can be modulated for fine tuning of gene expression as desired.
FILED Friday, June 28, 2019
APPL NO 16/456556
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/47 (20130101)
C07K 2319/81 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8216 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781195 Chung et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Yip-Wah Chung (Wilmette, Illinois);  Qian Wang (Mt. Prospect, Illinois);  Arman Mohammad Khan (Evanston, Illinois);  Tobias Vela Martin (Evanston, Illinois)
ABSTRACT Methods for forming carbon-based lubricious and/or wear-protective films in situ on the surface of steel alloys are provided. The methods use chromium-containing steel alloys, molybdenum-containing steel alloys, and steel alloys that contain both copper and nickel. When such alloys are subjected to a rubbing motion in the presence of a hydrocarbon fluid, the chromium, molybdenum, copper, and nickel in the steel alloy catalyzes the formation of solid carbon-containing films that reduce the friction, wear, or both of the contacting surfaces.
FILED Tuesday, December 14, 2021
APPL NO 17/550951
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 1/58 (20130101)
C21D 1/60 (20130101)
C21D 1/613 (20130101)
C21D 8/0205 (20130101)
C21D 8/0278 (20130101) Original (OR) Class
C21D 2201/00 (20130101)
C21D 2211/001 (20130101)

Alloys
C22C 38/22 (20130101)
C22C 38/24 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/1204 (20130101)
C23C 18/1241 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781437 Karafillis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Apostolos Pavlos Karafillis (Winchester, Massachusetts);  Eric Dean Jorgensen (Upton, Massachusetts);  Craig Douglas Young (Blanchester, Ohio);  Jonathan Harry Kerner (Brookline, Massachusetts);  Leonardo Ajdelsztajn (Niskayuna, New York)
ABSTRACT A component for a turbine engine may be formed by spraying particulate with a nozzle toward a substrate. The particulate may be deposited to form one or more annular layers and a reinforcing structure. The component may be a closed loop annular component having a reinforcing structure of specific dimensions enabled by the methods described.
FILED Tuesday, May 04, 2021
APPL NO 17/307394
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/12 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 9/06 (20130101) Original (OR) Class
F01D 25/24 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2230/31 (20130101)
F05D 2240/128 (20130101)
F05D 2260/606 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781448 Holleran
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Aeronautical Systems Center (ASC)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Mark Anthony Holleran (Cincinnati, Ohio)
ABSTRACT A shroud assembly is provided for a gas turbine engine defining an axial direction, a radial direction, and a circumferential direction. The shroud assembly includes: a shroud segment extending substantially along the circumferential direction and including a shroud wall, the shroud wall defining a shroud attachment opening; a hanger assembly including a hanger wall defining a hanger attachment opening; and an attachment pin assembly including a first member defining an interference fit with the hanger wall through the hanger attachment opening and including a shoulder contacting the hanger wall, the first member further extending through the shroud attachment opening and defining a hollow core; and a second member extending through the hollow core of the first member, the second member extending between a first end and a second end, the second member including a rim at the first end and a secondary attachment member at the second end.
FILED Tuesday, April 05, 2022
APPL NO 17/713515
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 11/08 (20130101)
F01D 25/005 (20130101)
F01D 25/28 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/11 (20130101)
F05D 2260/36 (20130101)
F05D 2300/6033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781791 Mahmoud et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Carrier Corporation (Palm Beach Gardens, Florida)
ASSIGNEE(S) Carrier Corporation (Palm Beach Gardens, Florida)
INVENTOR(S) Ahmad M. Mahmoud (Bolton, Connecticut);  Jinliang Wang (Ellington, Connecticut);  Frederick J. Cogswell (Glastonbury, Connecticut);  Parmesh Verma (South Windsor, Connecticut)
ABSTRACT A method for operating a heat pump (20; 300) includes operating in a cooling mode wherein heat is absorbed by refrigerant in the indoor heat exchanger (26) and rejected by refrigerant in the outdoor heat exchanger (24). The heat pump switches to operation in a heating mode wherein heat is rejected by refrigerant in the indoor heat exchanger, heat is absorbed by refrigerant in the outdoor heat exchanger, and there is an ejector (60) motive flow and ejector secondary flow. In the heating mode a refrigerant pressure (PH) or temperature (TL) is measured and, responsive to the measured refrigerant pressure or temperature, at least one of a fan speed is changed and a needle (132) of the ejector is actuated.
FILED Thursday, May 23, 2019
APPL NO 17/253855
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 13/00 (20130101) Original (OR) Class
F25B 41/42 (20210101)
F25B 49/02 (20130101)
F25B 2313/0293 (20130101)
F25B 2341/0013 (20130101)
F25B 2400/23 (20130101)
F25B 2600/11 (20130101)
F25B 2700/1931 (20130101)
F25B 2700/1933 (20130101)
F25B 2700/21162 (20130101)
F25B 2700/21163 (20130101)
F25B 2700/21174 (20130101)
F25B 2700/21175 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781814 Kasim
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Arlington, Virginia)
INVENTOR(S) Kawthar Kasim (Long Beach, California)
ABSTRACT A tapered groove width heat pipe is disclosed, including a tube having an internal surface, a first end, a second end, and a central axis. A plurality of groove walls on the internal surface define a plurality of trapezoidal grooves. Each groove wall has a proximal width closest to the central axis and a distal width furthest from the central axis, the proximal width of a portion of each groove wall tapering gradually between the first end and the second end.
FILED Monday, March 16, 2020
APPL NO 16/820701
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 15/04 (20130101)
F28D 15/046 (20130101)
F28D 15/0233 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781967 McDonnell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) James McDonnell (West Chester, Pennsylvania);  Lisa Weiser (Cherry Hill, New Jersey);  Jaime Santiago (Annapolis, Maryland);  Colin Ratcliffe (Millersville, Maryland)
ABSTRACT A device and method are provided for determining whether a laminate is bonded or debonded from its substrate. The device and method provide simple, accurate, rapid, cost-effective, and reliable means for assessing the bonding state of a laminated substrate.
FILED Tuesday, December 31, 2019
APPL NO 16/731759
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 3/13 (20130101)

Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 1/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 3/34 (20130101)
G01N 3/066 (20130101)
G01N 19/04 (20130101) Original (OR) Class
G01N 2203/0039 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781993 Leo et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Sin Yen Leo (Gainesville, Florida);  Peng Jiang (Gainesville, Florida);  Tianwei Xie (Gainesville, Florida)
ABSTRACT Embodiments of the present disclosure provide for methods of detecting, sensors (e.g., chromogenic sensor), kits, compositions, and the like that related to or use tunable macroporous polymer. In an aspect, tunable macroporous materials as described herein can be used to determine the presence of a certain type(s) and quantity of liquid in a liquid mixture.
FILED Tuesday, September 06, 2022
APPL NO 17/903312
ART UNIT 1758 — Optics
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/81 (20130101)
C08G 18/6755 (20130101)
C08G 2101/00 (20130101)
C08G 2280/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/26 (20130101)
C08J 2201/0442 (20130101)
C08J 2205/044 (20130101)
C08J 2375/14 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/25 (20130101)
G01N 21/78 (20130101) Original (OR) Class
G01N 21/255 (20130101)
G01N 21/272 (20130101)
G01N 33/2852 (20130101)
G01N 2021/7723 (20130101)
G01N 2021/7773 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782039 Rubenstein
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) H. Mitchell Rubenstein (Beavercreek, Ohio)
ABSTRACT A method for reducing the variability, as measured by relative standard deviation (RSD), of an analytical testing technique is provided. This improvement in RSD improves the confidence in the values obtained during field testing. The method includes incorporating a focusing agent into the sampling media, which permits providing sampling media such as thermal desorption tubes preloaded with the focusing agent.
FILED Wednesday, July 21, 2021
APPL NO 17/381810
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Separation
B01D 53/025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/405 (20130101)
G01N 30/08 (20130101)
G01N 30/7206 (20130101)
G01N 30/8668 (20130101)
G01N 33/0006 (20130101)
G01N 33/0057 (20130101) Original (OR) Class
G01N 2030/025 (20130101)
G01N 2030/085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782047 Alden et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Jonathan Alden (Ithaca, New York);  Alejandro Cortese (Ithaca, New York);  Arthur Barnard (Hayward, California);  Paul McEuen (Newfield, New York)
ABSTRACT A nanopore-containing substrate includes a substrate, a membrane on the substrate, and at least one nanoscale electronic element disposed on or embedded in the membrane. The membrane defines at least one nanopore. The nanoscale electronic element is aligned with one of the nanopores such that a shortest distance between an edge of the nanoscale electronic element and the edge of the nanopore is less than 50 nm. The nanopores may be formed by etching through a dielectric layer using a solution while applying a voltage to the nanoscale electronic element relative to the solution. The nanopore-containing substrate can be used to detect or sequence a biopolymer, such as a nucleic acid. The nanopore-containing substrate may be used with a biopolymer detection and/or sequencing system.
FILED Monday, May 17, 2021
APPL NO 17/322168
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4145 (20130101)
G01N 27/4146 (20130101)
G01N 27/44791 (20130101)
G01N 33/48721 (20130101) Original (OR) Class
G01N 33/54366 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782064 Linghu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Changyang Linghu (Cambridge, Massachusetts);  Shannon L. Johnson (Cambridge, Massachusetts);  Edward Stuart Boyden (Chestnut Hill, Massachusetts)
ABSTRACT The invention, in some aspects, relates to the preparation and use of signaling reporter islands (SiRIs) in single cells. Compositions of the invention that produce SiRIs can be delivered to a cell resulting in the presence of one or more SiRIs in the cell. Methods of the invention include detecting signals generated by elements in the SiRIs in a cell and use of the detected signals to determine and analyze simultaneous physiological processes within the cell, or cells.
FILED Monday, September 14, 2020
APPL NO 17/020803
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/705 (20130101)
C07K 2319/01 (20130101)
C07K 2319/60 (20130101)
C07K 2319/735 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/10 (20130101)
C12N 15/62 (20130101)
C12N 15/63 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
G01N 33/5005 (20130101)
G01N 33/6872 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782163 McVey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) THE AEROSPACE CORPORATION (El Segundo, California)
INVENTOR(S) John McVey (El Segundo, California);  Henry Helvajian (El Segundo, California);  Shawn Perdue (El Segundo, California);  Glenn Peterson (El Segundo, California);  Marlon Sorge (El Segundo, California);  David Cardoza (El Segundo, California);  Joseph Gangestad (El Segundo, California)
ABSTRACT Systems, apparatuses, and methods for identifying and tracking objects (e.g., debris, particles, space vehicles, etc.) using one or more light detection and ranging (LIDAR)-based sensors are disclosed. Such systems, apparatuses, and methods may be particularly beneficial for detecting millimeter scale and/or sub-millimeter scale objects. Such systems, apparatuses, and methods may be used for detection of objects in space, in the atmosphere, or in the ocean, for example.
FILED Friday, July 26, 2019
APPL NO 16/522789
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/481 (20130101)
G01S 17/89 (20130101)
G01S 17/931 (20200101) Original (OR) Class
G01S 17/933 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782194 Mitchell
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) WAVEFRONT RESEARCH, INC. (Northampton, Pennsylvania)
ASSIGNEE(S) Wavefront Research, Inc. (Northhampton, Pennsylvania)
INVENTOR(S) Thomas A. Mitchell (Arrington, Tennessee)
ABSTRACT Configurable afocal optical system that can be configured to have different magnifications, including unity magnification, and which are capable of being cascaded to produce any number of magnifications.
FILED Saturday, June 11, 2022
APPL NO 17/838194
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/08 (20130101)
G02B 5/0278 (20130101)
G02B 5/0284 (20130101) Original (OR) Class
G02B 27/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782264 Lentz
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Joshua K Lentz (Niceville, Florida)
ABSTRACT The systems and methods provided herein are directed to a flight motion simulator. The target axes are replaced by a system of Risley pairs. Light is projected to the unit under testing at a range of angles by rotating elements within the Risley pairs.
FILED Thursday, October 01, 2020
APPL NO 17/061525
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 26/0891 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782779 Albert et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Victor V. Albert (New Haven, Connecticut);  Shantanu Mundhada (New Haven, Connecticut);  Alexander Grimm (New Haven, Connecticut);  Steven Touzard (New Haven, Connecticut);  Michel Devoret (New Haven, Connecticut);  Liang Jiang (Guilford, Connecticut)
ABSTRACT Techniques for quantum error correction of a multi-level system are provided and described. In some aspects, techniques for encoding a state of a multi-level quantum system include encoding a quantum information in a two-mode state of two quantum mechanical oscillators. Techniques for protecting the two-mode state against dephasing and energy loss are described.
FILED Saturday, January 05, 2019
APPL NO 16/959209
ART UNIT 2896 — Optics
CURRENT CPC
Electric Digital Data Processing
G06F 11/0736 (20130101)
G06F 11/0751 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)
G06N 10/70 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782786 Gilton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Jeffrey S. Gilton (Cincinnati, Ohio);  Matthew B. Pfenninger (Cincinnati, Ohio);  Serge Rosine (Cincinnati, Ohio)
ABSTRACT A method to be performed by a processor includes determining whether an application software has called an application programming interface, upon determination that the application software has called the application programming interface, determining whether one or more floating-point errors are recorded in a floating-point status register, and upon determination that one or more floating-point errors are recorded in the floating-point status register, performing a predefined action for each type of floating-point error recorded in the floating-point status register.
FILED Thursday, March 17, 2022
APPL NO 17/697465
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 9/3013 (20130101)
G06F 11/0721 (20130101)
G06F 11/0793 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783169 Fok et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Femtosense, Inc. (San Bruno, California)
ASSIGNEE(S) Femtosense, Inc. (San Bruno, California)
INVENTOR(S) Sam Brian Fok (San Leandro, California);  Alexander Smith Neckar (Redwood City, California)
ABSTRACT Systems, apparatus, and methods for thread-based scheduling within a multicore processor. Neural networking uses a network of connected nodes (aka neurons) to loosely model the neuro-biological functionality found in the human brain. Various embodiments of the present disclosure use thread dependency graphs analysis to decouple scheduling across many distributed cores. Rather than using thread dependency graphs to generate a sequential ordering for a centralized scheduler, the individual thread dependencies define a count value for each thread at compile-time. Threads and their thread dependency count are distributed to each core at run-time. Thereafter, each core can dynamically determine which threads to execute based on fulfilled thread dependencies without requiring a centralized scheduler.
FILED Monday, January 02, 2023
APPL NO 18/149145
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/48 (20130101)
G06F 9/3802 (20130101)
G06F 9/3818 (20130101)
G06F 9/3836 (20130101)
G06F 9/3838 (20130101)
G06F 9/3851 (20130101)
G06F 9/3885 (20130101)
G06F 11/3024 (20130101)
G06F 11/3433 (20130101)
G06F 15/16 (20130101)
G06F 15/7807 (20130101)
G06F 16/901 (20190101)
G06F 17/16 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/10 (20130101)
G06N 3/045 (20230101)
G06N 3/048 (20230101)
G06N 3/063 (20130101) Original (OR) Class

Coding; Decoding; Code Conversion in General
H03M 7/702 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783196 O'Shea
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia)
ASSIGNEE(S) Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia)
INVENTOR(S) Timothy James O'Shea (Arlington, Virginia)
ABSTRACT Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training and deploying machine-learned identification of radio frequency (RF) signals. One of the methods includes: determining an RF signal configured to be transmitted through an RF band of a communication medium; determining first classification information that is associated with the RF signal, and that includes a representation of a characteristic of the RF signal or a characteristic of an environment in which the RF signal is communicated; using at least one machine-learning network to process the RF signal and generate second classification information as a prediction of the first classification information; calculating a measure of distance between (i) the second classification information that was generated by the at least one machine-learning network, and (ii) the first classification information associated with the RF signal; and updating the at least one machine-learning network based on the measure of distance.
FILED Friday, May 01, 2020
APPL NO 16/864516
ART UNIT 2198 — Computer Architecture and I/O
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/045 (20230101)
G06N 3/086 (20130101) Original (OR) Class
G06N 20/00 (20190101)

Transmission
H04B 17/30 (20150115)

Wireless Communication Networks
H04W 24/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784035 Cooks
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana)
ABSTRACT The invention generally relates to systems and methods for conducting reactions and screening for reaction products.
FILED Wednesday, January 25, 2023
APPL NO 18/101265
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/0013 (20130101)
H01J 49/165 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784274 Hart et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) SolAero Technologies Corp. (Albuquerque, New Mexico)
ASSIGNEE(S) SolAero Technologies Corp (Albuquerque, New Mexico)
INVENTOR(S) John Hart (Albuquerque, New Mexico);  Daniel Derkacs (Albuquerque, New Mexico);  Zachary Bittner (Albuquerque, New Mexico);  Andrew Espenlaub (Albuquerque, New Mexico)
ABSTRACT A multijunction solar cell including an upper first solar subcell having a first band gap and positioned for receiving an incoming light beam; a second solar subcell disposed below and adjacent to and lattice matched with said upper first solar subcell, and having a second band gap smaller than said first band gap; wherein at least one of the solar subcells has a graded band gap throughout the thickness of at least a portion of the active layer of the one solar subcell.
FILED Thursday, January 13, 2022
APPL NO 17/574750
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/065 (20130101)
H01L 31/184 (20130101)
H01L 31/0725 (20130101) Original (OR) Class
H01L 31/0735 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784358 Nemanick et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) THE AEROSPACE CORPORATION (El Segundo, California)
INVENTOR(S) Eric Joseph Nemanick (Santa Monica, California);  Ann L. Chervenak (Los Angeles, California);  Joseph Z. Fuerst (Beavercreek, Ohio);  Andrew Brethorst (Hawthorne, California);  Michael R. Hale (West Hollywood, California);  Kevin Macdougall (Torrance, California);  Justin Stocker (Sherman Oaks, California)
ABSTRACT A self-regulating battery may generate a basis state for one or more modules using one or more system inputs. The system inputs comprise current, voltage, and battery degradation. The battery generates a family of weighted forecasts for future bus demands using usage and performance based weights. The battery generates one or more plans to support demand from the battery using the weighted forecasts. The battery scores the one or more plans based on efficiency of power extraction from the battery, and combines the scored one or more plans with an updated SoH value based on induced degradation from a usage plan. The battery generates the combined scored for each of the one or more plans, and transmits one of the combined scored to the battery management unit for execution.
FILED Wednesday, July 07, 2021
APPL NO 17/369895
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/48 (20130101) Original (OR) Class
H01M 10/4257 (20130101)
H01M 2010/4271 (20130101)
H01M 2010/4278 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784571 Kerber et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) Naval Information Warfare Center Pacific (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Maxwell Mayekawa Kerber (San Diego, California);  Lewis Hsu (Honolulu, Hawaii);  Joseph F. Schnecker, Jr. (San Diego, California);  Alex G. Phipps (San Diego, California)
ABSTRACT An electrical network including a power source, a flyback converter, a microcontroller, a PID controller, a voltage boost converter, a pulse width modulator integrated circuit, and a battery. The power source produces a charge with a voltage ranging from about 0.1V to about 0.8V and a power ranging from about 0.3 mW to about 100 mW. The flyback converter functions in discontinuous current mode. The microcontroller monitors the power source voltage, calculates a voltage response, and outputs a control signal for the voltage. The PID controller is a digital PID controller, an analog PID controller, or a combination thereof. The voltage boost converter utilizes the power source voltage and power to provide higher voltage power to the electrical network. The pulse width modulator integrated circuit sets a duty cycle and frequency for the flyback converter. The battery stores excess charge produced by the power source.
FILED Thursday, July 29, 2021
APPL NO 17/388135
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 3/33515 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784616 Chang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California);  SoCal Simulations, LLC (Sacramento, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  SOCAL SIMULATIONS, LLC (Sacramento, California)
INVENTOR(S) Tammy Chang (San Ramon, California);  Adam Conway (Livermore, California);  Victor Valeryevich Khitrov (San Ramon, California);  Lars Voss (Livermore, Idaho);  Benjamin Fasenfest (Redding, California);  Peter Asbeck (Del Mar, California)
ABSTRACT Power amplifier apparatuses and techniques for optimizing the design of power amplifiers are disclosed. In one aspect, a method for optimizing a power amplifier includes selecting a circuit topology for the power amplifier. The circuit topology includes one or more photoconductive switches and an impedance matching network including one or more parameter values representative of the impedance matching network or the photoconductive switches that can be adjusted. The method further includes selecting one or more optimization goals for the impedance matching network and the one or more photoconductive switches, and adjusting the one or more parameter values according to the one or more optimization goals. The one or more optimization goals include an efficiency at a particular power output.
FILED Tuesday, March 16, 2021
APPL NO 17/202691
ART UNIT 2843 — Electrical Circuits and Systems
CURRENT CPC
Amplifiers
H03F 1/565 (20130101)
H03F 3/195 (20130101)
H03F 3/245 (20130101) Original (OR) Class
H03F 2200/318 (20130101)
H03F 2200/421 (20130101)
H03F 2200/423 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784641 Mehrotra et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S) NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina)
INVENTOR(S) Utkarsh Mehrotra (Raleigh, North Carolina);  Douglas C. Hopkins (Raleigh, North Carolina)
ABSTRACT Various examples are provided related to supercascode power switches that can be used in, e.g., HV and MV applications. This disclosure introduces a cascaded supercascode (CSC) power switch which can include a series of unit supercascode (USC) circuits; a control switch coupled in series with the series of USC circuits; and an external balancing network coupled to each of the n USC circuits. The series has a plurality of USC circuits, with each of the USC circuits including first and second switches coupled in series and an internal balancing network coupled across the first and second switches. A source of each of the USC circuits is a source of the first switch. The internal balancing network can include a capacitor connected between a gate of the second switch and the source of the first switch and a diode connected in parallel with the capacitor.
FILED Saturday, January 15, 2022
APPL NO 17/576921
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 17/102 (20130101)
H03K 17/161 (20130101)
H03K 17/6874 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784653 Zhao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Digital Analog Integration, Inc. (Auburn, Alabama)
ASSIGNEE(S) Digital Analog Integration, Inc. (Auburn, Alabama)
INVENTOR(S) Haoyi Zhao (Auburn, Alabama);  Fa Dai (Auburn, Alabama);  John David Irwin (Auburn, Alabama)
ABSTRACT An analog-to-digital converter includes a first converter stage, a second converter stage coupled to the first converter stage to quantize a residue signal of the first converter stage, and an inter-stage converter disposed between the first and second converter stages. The inter-stage converter is configured to convert between a first domain and a second domain. The inter-stage converter is configured to process the residue signal of the first converter stage such that a range of the residue signal matches a full scale of the second converter stage.
FILED Thursday, October 28, 2021
APPL NO 17/513476
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Time-interval Measuring
G04F 10/005 (20130101)

Coding; Decoding; Code Conversion in General
H03M 1/002 (20130101) Original (OR) Class
H03M 1/50 (20130101)
H03M 1/145 (20130101)
H03M 1/804 (20130101)
H03M 1/1009 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784710 Ge et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) THE AEROSPACE CORPORATION (El Segundo, California)
INVENTOR(S) Howard H. Ge (Hacienda Heights, California);  Erin Y. Hong (Lawndale, California);  Richard Y. Chiang (Torrance, California);  Devon Feaster (Torrance, California);  Tuong-Vi Thi Tran (Garden Grove, California);  Michael Andonian (Los Angeles, California)
ABSTRACT Embodiments of the present invention include a two-stage blending filter that blends the measurements from two angular sensors to form a single superior high bandwidth measurement for improved disturbance rejection in a satellite systems for increased accuracy in satellite pointing, orientation, and attitude control. Embodiments of the present invention can include a satellite system including a first sensor including or defining a first measurement bandwidth; a first filter connected to the first sensor; a second sensor including or defining a second measurement bandwidth; a second filter connected to the second sensor; and a third filter connected to the first filter and the second filter. The third filter blend the first signal and the second signal into a third signal; and transmit the third signal to a flight controller configured to adjust an orientation of the satellite, a satellite subsystem, or both, relative to a target in response to the third signal.
FILED Thursday, March 10, 2022
APPL NO 17/691696
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission
H04B 1/1018 (20130101)
H04B 7/18539 (20130101) Original (OR) Class
H04B 7/18591 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11785452 Harley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Peter Michael Baab Harley (Annapolis, Maryland);  Murali Tummala (Monterey, California);  John Colin Mceachen (Carmel, California)
ABSTRACT The invention relates to concealing information within error correction codes of adaptive rate wireless communication systems. In some embodiments, the invention includes selecting a modulation and coding scheme with a more robust error correction capacity than needed by current channel conditions; encoding a hidden message with a pre-shared key that is known by a covert transmitter and a covert receiver, and after a standard message is encoded by a transmitting station of the wireless communication systems, replacing codeword parity bits of codewords in the encoded standard message with the encoded hidden message at designated locations. Before a receiving station of the wireless communication systems decodes the encoded standard message, a covert receiver extracts the embedded hidden message from the encoded standard message, replaces bit values of the embedded hidden message with zero at the designated locations, and decodes the extracted hidden message with the pre-shared key.
FILED Friday, January 22, 2021
APPL NO 17/156425
ART UNIT 2495 — Cryptography and Security
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 13/353 (20130101)
H03M 13/1102 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0002 (20130101)
H04L 1/0054 (20130101)
H04L 1/0061 (20130101)
H04L 63/04 (20130101)

Wireless Communication Networks
H04W 12/037 (20210101) Original (OR) Class
H04W 12/0431 (20210101)
H04W 84/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11785561 Kwon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Wichita State University (Wichita, Kansas)
ASSIGNEE(S) WICHITA STATE UNIVERSITY (Wichita, Kansas)
INVENTOR(S) Hyuck M. Kwon (Wichita, Kansas);  Madhuprana Goswami (Wichita, Kansas);  Vidhi Rana (Wichita, Kansas);  Khanh Pham (Albuquerque, New Mexico)
ABSTRACT A satellite communications system is disclosed, the system comprising a ground controller, a decode-and-forward (DF) satellite transponder, and a digital high-power amplifier (HPA). The DF is further comprised of a transponder front end including a digital channelizer and a predistorter. The ground controller is configured to transmit multiple-access frequency-division-multiplexed signals to the DF, where the DF is configured to down-convert the signals received at the transponder front end. The digital channelizer is configured to convert the signals received into a single sample steam and feed the stream through the predistorter into the single digital HPA, wherein the HPA is configured to amplify each input sample of the stream in sample-by-sample fashion and generates a discrete output. The DF is further configured to convert the output of the digital HPA to a continuous time signal and up-convert the output with a main carrier frequency for down-link transmission to multiple-access ground users.
FILED Tuesday, June 29, 2021
APPL NO 17/361962
ART UNIT 2466 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 1/59 (20130101)
H04B 7/19 (20130101)
H04B 7/2621 (20130101)
H04B 7/18517 (20130101)

Wireless Communication Networks
H04W 52/52 (20130101) Original (OR) Class
H04W 52/243 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11779143 Howard
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Panit Clifton Howard (Albuquerque, New Mexico)
ABSTRACT A donning system allows a user to don disposable garments without contaminating the exterior of the garment. The disposable garment is part of a garment package, which also includes a cuff by which the garment is loaded into and dispensed from the donning system. The cuff includes elements whereby multiple garments are simultaneously loaded, but the garments are dispensed and donned one at a time. The donning system can include multiple cartridges allowing the user to don multiple garments simultaneously, such as right and left gloves or shoe covers. The donning system can include multiple chambers allowing the system to dispense garments of different sizes.
FILED Wednesday, February 03, 2021
APPL NO 17/165996
ART UNIT 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 19/0055 (20130101)
A41D 2400/44 (20130101)
A41D 2400/52 (20130101)

Characteristic Features of Footwear; Parts of Footwear
A43B 3/163 (20130101)

Household or Table Equipment
A47G 25/80 (20130101)
A47G 25/904 (20130101) Original (OR) Class

Diagnosis; Surgery; Identification
A61B 42/40 (20160201)
A61B 42/50 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779778 Friedman
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Integrated Sensors, LLC (Ottawa Hills, Ohio)
ASSIGNEE(S) Integrated Sensors, LLC (Palm Beach Gardens, Florida)
INVENTOR(S) Peter S. Friedman (Ottawa Hills, Ohio)
ABSTRACT Embodiments are directed generally to an ionizing-radiation beamline monitoring system that includes a vacuum chamber structure with vacuum compatible flanges through which an incident ionizing-radiation beam enters the monitoring system. Embodiments further include at least one scintillator within the vacuum chamber structure that can be at least partially translated in the ionizing-radiation beam while oriented at an angle greater than 10 degrees to a normal of the incident ionizing-radiation beam, a machine vision camera coupled to a light-tight structure at atmospheric/ambient pressure that is attached to the vacuum chamber structure by a flange attached to a vacuum-tight viewport window with the camera and lens optical axis oriented at an angle of less than 80 degrees with respect to a normal of the scintillator, and at least one ultraviolet (“UV”) illumination source facing the scintillator in the ionizing-radiation beam for monitoring a scintillator stability comprising scintillator radiation damage.
FILED Wednesday, October 20, 2021
APPL NO 17/451517
ART UNIT 2884 — Optics
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/00 (20130101)
A61N 5/1045 (20130101)
A61N 5/1048 (20130101)
A61N 5/1049 (20130101)
A61N 5/1064 (20130101)
A61N 5/1067 (20130101) Original (OR) Class
A61N 5/1077 (20130101)
A61N 2005/1059 (20130101)
A61N 2005/1087 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/29 (20130101)
G01T 1/40 (20130101)
G01T 1/1612 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779882 Pourpoint et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Timothee L. Pourpoint (West Lafayette, Indiana);  Utkarsh Pandey (Lafayette, Indiana);  Jonathan Poggie (West Lafayette, Indiana)
ABSTRACT A high enthalpy and low-cost Hypersonic Test Facility (HTF), which employs nitrous oxide to generate clean air-like gas; and a method of decomposing nitrous oxide in the presence of a catalyst in a catalytic decomposition chamber in a HTF.
FILED Thursday, April 07, 2022
APPL NO 17/715305
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/8628 (20130101) Original (OR) Class
B01D 53/8631 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780012 Anderson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Iver E. Anderson (Ames, Iowa);  Jordan A. Tiarks (Ames, Iowa);  Timothy E. Prost (Ames, Iowa);  Bo Kong (Ames, Iowa);  Emma H. White (Ames, Iowa);  Trevor M. Riedemann (Ames, Iowa);  Eric J. Deaton (Ames, Iowa);  Ross Anderson (Ames, Iowa);  David Byrd (Ames, Iowa);  Franz Hugolino Hernandez Gaitan (Ames, Iowa)
ABSTRACT The broad applicability of at least certain aspects of the present invention derives from the ability to determine the critical location where secondary satellite formation occurs for any atomization system or design and allows for the rapid assessment of the effectiveness of various satellite reduction strategies, including but not limited to several embodiments detailed herein. Aspects of this invention can be utilized during initial atomization system design in order to evaluate effective chamber geometries and enabling strategies which reduce/eliminate satelliting, or can be retrofit to existing systems and allows for economic evaluation of effectiveness based off of initial capital expenditures versus increased operating requirements/expenses.
FILED Wednesday, June 23, 2021
APPL NO 17/304586
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 9/082 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780122 Lojek, III et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania)
ASSIGNEE(S) Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania)
INVENTOR(S) John Lojek, III (Valencia, Pennsylvania);  Matthew M. Swartz (Claridge, Pennsylvania);  William A. Byers (Murrysville, Pennsylvania)
ABSTRACT A forming assembly configured to form a wick is disclosed. The forming assembly includes an expandable tube and a forming shell assembly. The expandable tube is hydraulically expandable to an expanded configuration. A wick mesh is configured to be wrapped about the expandable tube. The forming shell assembly includes a first forming shell comprising a first recess defined therein and a second forming shell comprising a second recess defined therein. The first recess and the second recess cooperate to define an outer diameter of the wick. The expandable tube and the wick mesh are positionable between the first recess and the second recess. The expandable tube and the forming shell assembly are configured to deform the wick mesh and form the wick based on the expandable tube hydraulically expanding towards the expanded configuration.
FILED Monday, April 20, 2020
APPL NO 16/853270
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 43/10 (20130101) Original (OR) Class
B29C 43/3642 (20130101)
B29C 2043/3602 (20130101)
B29C 2043/3649 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780389 Verma et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Kiren E. Verma (Oak Ridge, Tennessee);  Robert A. Bridges (Oak Ridge, Tennessee);  Samuel C Hollifield (Oak Ridge, Tennessee)
ABSTRACT A system and method for decoding an unknown automotive controller area network (“CAN”) message definitions. CAN data vehicle signal mappings are typically held in secret and varied by automotive model and year. Without knowledge of the mappings, the wealth of real-time vehicle data hidden in the automotive CAN packets is uninterpretable—impeding research, after-market tuning, efficiency and performance monitoring, fault diagnosis, and privacy-related technologies. This technology can ascertain the CAN signals' boundaries (start bit and length), endianness (byte ordering), signedness (binary-to-integer encoding) from raw CAN data. This allows conversion of CAN data to time series. Interpreting the translated CAN data's physical meaning and finding a linear mapping to standard units (e.g., knowing the signal is speed and scaling values to represent units of miles per hour) can be achieved for many signals by leveraging diagnostic standards to obtain real-time measurements of in-vehicle systems. The system and method can be integrated into lightweight hardware enabling an OBD-II plugin for real-time in-vehicle CAN decoding or run on standard computers. The system can output a standard DBC file with the signal definition information.
FILED Thursday, December 10, 2020
APPL NO 17/117535
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for
B60R 16/0232 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 5/008 (20130101)
G07C 5/10 (20130101)
G07C 5/0808 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780453 Aggoune et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados)
ASSIGNEE(S) DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados)
INVENTOR(S) Karim Aggoune (Auburn Hills, Michigan);  Frans M. Theunissen (Rochester Hills, Michigan)
ABSTRACT A method for assignment of vehicle control includes receiving route data indicating a route between a starting location of a vehicle and a destination location, and determining an optimal vehicle configuration for the route based on a target vehicle speed and a hybrid torque split. The method further includes receiving a driver requested torque value and determining a passive pedal torque value based on the route data and vehicle powertrain data. The method further includes selectively assigning control of the vehicle to a vehicle system or to a driver of the vehicle based on the driver requested torque value and the passive pedal torque value.
FILED Tuesday, September 29, 2020
APPL NO 17/035904
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 10/04 (20130101)
B60W 10/10 (20130101)
B60W 50/10 (20130101)
B60W 50/087 (20130101) Original (OR) Class
B60W 2510/0604 (20130101)
B60W 2520/30 (20130101)
B60W 2556/50 (20200201)
B60W 2710/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780787 Li et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Zhenglong Li (Knoxville, Tennessee);  Andrew Sutton (Oak Ridge, Tennessee);  Cameron M. Moore (White Rock, New Mexico);  Michael Cordon (Knoxville, Tennessee)
ABSTRACT A method for converting a diol in solution to an olefin fraction, the method comprising: (i) reacting a diol of the formula HO—R—OH in solution with a carbonyl-containing molecule of the formula:
in the presence of an acid catalyst to result in a dioxolane molecule of the formula:
wherein R is a hydrocarbon linker containing 1-12 carbon atoms, and R1 and R2 are independently selected from hydrogen atom and hydrocarbon groups containing 1-12 carbon atoms, wherein R1 and R2 optionally interconnect; (ii) removing the dioxolane molecule from the solution by phase separation; and (iii) contacting the dioxolane molecule with a metal-loaded zeolite at a temperature of 100-500° C. to convert the dioxolane molecule to an olefin fraction.
FILED Wednesday, February 01, 2023
APPL NO 18/104545
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 29/40 (20130101)

Acyclic or Carbocyclic Compounds
C07C 2/46 (20130101) Original (OR) Class
C07C 7/11 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780829 Thompson et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The University of Southern California (Los Angeles, California)
ASSIGNEE(S) The University of Southern California (Los Angeles, California)
INVENTOR(S) Mark E. Thompson (Anaheim, California);  Abegail Tadle (Bakersfield, California);  Karim El Roz (Los Angeles, California);  Peter Ivan Djurovich (Long Beach, California);  Daniel Sylvinson Muthiah Ravinson (Los Angeles, California);  Jessica H. Golden (Berkeley, California);  Stuart W. Sawyer (South Hampton, United Kingdom)
ABSTRACT A compound of Formula X wherein ring A is absent, or present and selected from a 5-membered or 6-membered, carbocyclic or heterocyclic ring, which is optionally substituted; ring B is absent, or present and selected from a 5-membered or 6-membered, carbocyclic or heterocyclic ring, which is optionally substituted; and at least one of ring A or ring B is present, and the hash line represents ring A fused to ring N—W1—W3 and ring B fused to ring N—W4—W6; W1, W2, W3, W4, W5, and W6 are independently selected from CR1 or N; Z is selected from CRZ or N; and Y is selected from a group consisting of C(R2)2, B(R2)2, Al(R2)2, Si(R2)2, and Ge(R2)2. An optoelectronic device selected from the group consisting of a photovoltaic device, a photodetector device, a photosensitive device, and an OLED, the optoelectronic device including an organic layer that comprises a compound of Formula X. A consumer product that includes the optoelectronic device.
FILED Thursday, January 16, 2020
APPL NO 16/744728
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 209/82 (20130101)
C07D 251/24 (20130101)
C07D 333/54 (20130101)
C07D 403/04 (20130101)
C07D 403/14 (20130101)
C07D 405/14 (20130101) Original (OR) Class
C07D 409/14 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/0812 (20130101)

Organic electric solid-state devices
H10K 85/40 (20230201)
H10K 85/622 (20230201)
H10K 85/6572 (20230201)
H10K 85/6574 (20230201)
H10K 85/6576 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780891 Gruver et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) PIONEER HI-BRED INTERNATIONAL, INC. (Johnston, Iowa)
ASSIGNEE(S) PIONEER HI-BRED INTERNATIONAL, INC. (, None)
INVENTOR(S) Steven D Gruver (Pacifica, California);  Heather Kozy (Walnut Creek, California);  Jessica O'Rear (Redwood City, California);  Barbara Rosen (Mountain View, California);  Ute Schellenberger (Palo Alto, California);  Jun-Zhi Wei (Johnston, Iowa);  Weiping Xie (East Palo Alto, California);  Xiaohong Zhong (San Leandro, California);  Genhai Zhu (San Jose, California)
ABSTRACT Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
FILED Wednesday, November 03, 2021
APPL NO 17/453439
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 37/46 (20130101)
A01N 63/27 (20200101)
A01N 63/50 (20200101)
A01N 63/50 (20200101)

Peptides
C07K 14/21 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8286 (20130101)

Technologies for Adaptation to Climate Change
Y02A 40/146 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780938 Hartmann-Thompson et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota)
ASSIGNEE(S) 3M Innovative Properties Company (St. Paul, Minnesota)
INVENTOR(S) Claire Hartmann-Thompson (Lake Elmo, Minnesota);  Mark J. Pellerite (Woodbury, Minnesota);  Carl A. Laskowski (Minneapolis, Minnesota);  John Christopher Thomas (St. Paul, Minnesota);  Marina M. Kaplun (Woodbury, Minnesota)
ABSTRACT Cationic polymers are provided that comprise monomeric units of Formula (V). (V) Each asterisk (*) indicates an attachment position to another monomeric unit; R is hydrogen or methyl; each R2 is each independently an alkyl, aryl, or a combination thereof; L is a linking group comprising an alkylene group; and +R3 is a cationic nitrogen-containing group free of any N—H bonds. Membranes formed from said cationic polymers, devices including such membranes, and methods of making such cationic polymers are also provided.
FILED Thursday, December 03, 2020
APPL NO 17/756324
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/32 (20130101)
C08F 8/42 (20130101) Original (OR) Class
C08F 297/04 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/2243 (20130101)
C08J 2353/02 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 50/414 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780985 Delferro et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Massimiliano Delferro (Chicago, Illinois);  Magali S. Ferrandon (Steger, Illinois);  Robert M. Kennedy (Lemont, Illinois);  Gokhan Celik (Lemont, Illinois);  Ryan Hackler (Lemont, Illinois);  Kenneth Poeppelmeier (Evanston, Illinois);  Aaron D. Sadow (Ames, Iowa)
ABSTRACT A method of upcycling polymers to useful hydrocarbon materials. A catalyst with nanoparticles on a substrate selectively docks and cleaves longer hydrocarbon chains over shorter hydrocarbon chains. The nanoparticles exhibit an edge to facet ratio to provide for more interactions with the facets.
FILED Monday, August 24, 2020
APPL NO 17/000969
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/42 (20130101)
B01J 35/023 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/50 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 11/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781107 Beckham et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Gregg Tyler Beckham (Golden, Colorado);  Christopher W. Johnson (Denver, Colorado);  Allison Jean Zimont Werner (Denver, Colorado);  Davinia Salvachúa Rodríguez (Golden, Colorado);  Daniel A. Jacobson (Oak Ridge, Tennessee);  Erica Teixeira Prates (Oak Ridge, Tennessee);  Elsayed Tharwat Tolba Mohamed (Helsingborg, Sweden);  Adam Michael Feist (Oakland, California)
ABSTRACT Disclosed herein are the genetically modified Pseudomonas with improved tolerance to hydroxycinnamic acids.
FILED Wednesday, February 24, 2021
APPL NO 17/184580
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/205 (20210501) Original (OR) Class
C12N 15/78 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/38 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781199 Manuel et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  UTBATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Michele Viola Manuel (Gainesville, Florida);  Hunter B. Henderson (Gainesville, Florida);  Orlando Rios (Oak Ridge, Tennessee);  Gerard M. Ludtka (Oak Ridge, Tennessee)
ABSTRACT Disclosed herein is a method comprising disposing a container containing a metal and/or ferromagnetic solid and abrasive particles in a static magnetic field; where the container is surrounded by an induction coil; activating the induction coil with an electrical current, to heat up the metallic or ferromagnetic solid to form a fluid; generating sonic energy to produce acoustic cavitation and abrasion between the abrasive particles and the container; and producing nanoparticles that comprise elements from the container, the metal and/or the ferromagnetic solid and the abrasive particles. Disclosed herein too is a composition comprising first metal or a first ceramic; and particles comprising carbides and/or nitrides dispersed therein. Disclosed herein too is a composition comprising nanoparticles comprising chromium carbide, iron carbide, nickel carbide, γ-Fe and magnesium nitride.
FILED Thursday, February 23, 2023
APPL NO 18/173158
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/00 (20130101)
B22F 1/07 (20220101)
B22F 1/12 (20220101)
B22F 1/054 (20220101)
B22F 9/04 (20130101)
B22F 9/06 (20130101)
B22F 2009/042 (20130101)
B22F 2009/045 (20130101)
B22F 2202/01 (20130101)
B22F 2202/05 (20130101)
B22F 2202/07 (20130101)
B22F 2301/058 (20130101)
B22F 2302/10 (20130101)
B22F 2302/20 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Alloys
C22C 1/1084 (20130101) Original (OR) Class
C22C 1/1084 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 1/00 (20130101)
C25D 15/00 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/0036 (20130101)
H01F 1/047 (20130101)
H01F 1/442 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 6/367 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781379 Zhang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Xiaosheng Zhang (Berkeley, California);  Ming Chiang A Wu (Moraga, California);  Andrew S Michaels (Berkeley, California);  Johannes Henriksson (Berkeley, California)
ABSTRACT An integrated-optics MEMS-actuated beam-steering system is disclosed, wherein the beam-steering system includes a lens and a programmable vertical coupler array having a switching network and an array of vertical couplers, where the switching network can energize of the vertical couplers such that it efficiently emits the light into free-space. The lens collimates the light received from the energized vertical coupler and directs the output beam along a propagation direction determined by the position of the energized vertical coupler within the vertical-coupler array. In some embodiments, the vertical coupler is configured to correct an aberration of the lens. In some embodiments, more than one vertical coupler can be energized to enable steering of multiple output beams. In some embodiments, the switching network is non-blocking.
FILED Thursday, July 14, 2022
APPL NO 17/865131
ART UNIT 2874 — Optics
CURRENT CPC
Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates
E06B 9/34 (20130101)
E06B 9/42 (20130101)
E06B 9/80 (20130101) Original (OR) Class
E06B 9/325 (20130101)
E06B 9/326 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/292 (20130101)
G02F 1/3132 (20130101)
G02F 1/3137 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781469 Heher et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Transportation IP Holdings, LLC (Norwalk, Connecticut)
ASSIGNEE(S) Transportation IP Holdings, LLC (Norwalk, Connecticut)
INVENTOR(S) Brett Heher (Pittsburgh, Pennsylvania);  Adam Edgar Klingbeil (Ballston Lake, New York);  Manuel Licon Flores (Erie, Pennsylvania);  Kevin Paul Bailey (Mercer, Pennsylvania)
ABSTRACT An insert device includes a body having an upper body portion configured to couple with a cylinder head of an engine cylinder and a lower body portion extending from the upper body portion toward a combustion chamber of the engine cylinder. The body includes an interior surface extending around a central volume positioned to receive liquid fuel from a fuel injector. The body includes gas inlet channels and fuel-and-gas mixture outlet channels. The gas inlet channels direct gas into the central volume where the gas mixes with the liquid fuel to form the fuel-and-gas mixture. The fuel-and-gas mixture outlet channels direct the mixture into the combustion chamber. The interior surface includes concave surface portions between the inlet channels and the outlet channels along a center axis of the body that are shaped to direct the gas into the central volume toward the liquid fuel in the central volume.
FILED Thursday, August 12, 2021
APPL NO 17/401284
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 23/232 (20220101)
B01F 25/3142 (20220101)
B01F 2101/503 (20220101)

Internal-combustion Piston Engines; Combustion Engines in General
F02B 23/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781814 Kasim
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Arlington, Virginia)
INVENTOR(S) Kawthar Kasim (Long Beach, California)
ABSTRACT A tapered groove width heat pipe is disclosed, including a tube having an internal surface, a first end, a second end, and a central axis. A plurality of groove walls on the internal surface define a plurality of trapezoidal grooves. Each groove wall has a proximal width closest to the central axis and a distal width furthest from the central axis, the proximal width of a portion of each groove wall tapering gradually between the first end and the second end.
FILED Monday, March 16, 2020
APPL NO 16/820701
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 15/04 (20130101)
F28D 15/046 (20130101)
F28D 15/0233 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781839 Barr et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Christian Barr (Kansas City, Missouri);  Justin Tannehill (Kansas City, Missouri)
ABSTRACT A multi-layer body armor plate includes a strike plate; a mesh layer positioned over the strike plate, the mesh layer having a number of open cells; and an outer skin layer positioned over the mesh layer so as to encapsulate the open cells of the mesh layer between the strike plate and the outer skin layer. The open cells of the mesh layer may entrap air or may be filled with expandable, buoyant foam.
FILED Friday, February 26, 2021
APPL NO 17/186311
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 3/12 (20130101)
B32B 15/16 (20130101)
B32B 15/046 (20130101)
B32B 2260/025 (20130101)
B32B 2264/04 (20130101)
B32B 2307/558 (20130101)
B32B 2571/02 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 80/00 (20141201)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 5/04 (20130101)
F41H 5/08 (20130101)
F41H 5/0442 (20130101)
F41H 5/0457 (20130101) Original (OR) Class
F41H 5/0492 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781958 Nation et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Brendan L. Nation (Albuquerque, New Mexico);  Michael T. Dugger (Tijeras, New Mexico);  John Curry (Albuquerque, New Mexico)
ABSTRACT The present invention relates, in part, to systems for characterizing force (e.g., friction, wear, and/or torque). In one embodiment, the system allows for wear testing of samples in a high throughput manner. In another embodiment, the system allows for torque sensing in a non-contact manner.
FILED Wednesday, August 11, 2021
APPL NO 17/399954
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 3/08 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 3/02 (20130101)
G01N 3/56 (20130101) Original (OR) Class
G01N 21/27 (20130101)
G01N 2201/08 (20130101)
G01N 2201/063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781975 Smith
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Mark W. Smith (Albuquerque, New Mexico)
ABSTRACT A remote sensor system comprising a laser transmitter that emits a pulse of broadband laser illumination comprising a plurality of wavelengths and a receiver configured to detect laser illumination backscatter. The sensor system further includes a computing system configured to determine a plurality of species number densities along a travel path of the laser illumination. Determining the plurality of species number densities includes determining a first number density of a first species based on a first set of optical transmission values from the backscatter data for a first subset of wavelengths of the plurality of wavelengths and a first attenuation cross-section of the first species. Additional species are determined based on additional sets of optical transmission values from the backscatter data for additional subsets of wavelengths of the plurality of wavelengths and additional cross-sections of additional species.
FILED Thursday, September 23, 2021
APPL NO 17/482619
ART UNIT 2896 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/03 (20130101) Original (OR) Class
G01N 2201/06113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782007 Rhoads et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Jeffrey Frederick Rhoads (West Lafayette, Indiana);  George Tsu-Chih Chiu (West Lafayette, Indiana);  Bryan W Boudouris (West Lafayette, Indiana);  Nikhil Bajaj (West Lafayette, Indiana);  Allison Kelly Murray (West Lafayette, Indiana);  Zachary A Siefker (West Lafayette, Indiana);  Xikang Zhao (West Lafayette, Indiana)
ABSTRACT The present disclosure relates to a novel composite film configured for CO2 sensing, and the method of making and using the novel composite film. The novel composite film comprises a carbon nanotube film and a CO2 absorbing layer deposited on the carbon nanotube film, wherein the CO2 absorbing layer comprises a mixture of a branched polyethylenimine, a polyethylene glycol, and poly[1-(4-vinylbenzyl)-3-methylimidazolium tetrafluoroborate] of formula I: wherein n ranges from 10-300.
FILED Thursday, August 06, 2020
APPL NO 16/986340
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 9/007 (20130101)
B32B 9/045 (20130101)
B32B 27/302 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 30/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/174 (20170801)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 73/0206 (20130101)

Compositions of Macromolecular Compounds
C08L 71/02 (20130101)
C08L 79/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/126 (20130101)
G01N 27/127 (20130101) Original (OR) Class
G01N 33/004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782154 Sloan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) George R. Sloan (Albuquerque, New Mexico);  Tucker Caelan Ellis Haydon (Albuquerque, New Mexico)
ABSTRACT Various embodiments described herein provide for a terrain-aided location determination using a range/angle radar altimetry. Range/angle radar systems use vertical synthetic aperture radar measurements which do not include any cross-track resolution, such that if a range/Doppler cloud from a single VSAR image is compared to a regular DEM, there can be ambiguity in determining the cross-track position. By modifying the DEM to inherently include additional terrain signature information that could be compared to VSAR measurement, the limitation can be overcome, and a single range/angle radar system can provide an accurate position without the additional complexity of a range/angle/angle radar system.
FILED Monday, November 01, 2021
APPL NO 17/515720
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/933 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782164 Mostafanezhad et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Nalu Scientific, LLC (Honolulu, Hawaii)
ASSIGNEE(S) Nalu Scientific, LLC (Honolulu, Hawaii)
INVENTOR(S) Isar Mostafanezhad (Honolulu, Hawaii);  Luca Macchiarulo (Honolulu, Hawaii);  Dean Uehara (Honolulu, Hawaii);  Christopher Chock (Honolulu, Hawaii);  Benjamin Rotter (Honolulu, Hawaii);  Ruth Perron (Honolulu, Hawaii);  Gregory Uehara (Kailua, Hawaii)
ABSTRACT Diverse applications from particle physics experiments to lidar are driving cost and current reduction in giga-hertz sampling rate high-resolution data conversion. Multiple imagers captures a single pixel of data and require processing at very high speed. High-bandwidth high-rate signal sampling, analog-to-digital conversion, and transfer of large amounts of data to a digital data acquisition block are required in such systems. Dynamic range, power consumption, and transfer of high-speed, high-bit width data are key implementation challenges. Data acquisition architectures optimized for specific requirements of such systems may facilitate system implementation and reduce overall system cost.
FILED Monday, November 01, 2021
APPL NO 17/515745
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 30/08 (20130101)
B60W 2420/42 (20130101)
B60W 2420/52 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 17/931 (20200101) Original (OR) Class

Coding; Decoding; Code Conversion in General
H03M 1/188 (20130101)
H03M 1/1245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782181 Kasten et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) GE Energy Oilfield Technology, Inc. (Broussard, Louisiana)
ASSIGNEE(S) GE Energy Oilfield Technology, Inc. (Broussard, Louisiana)
INVENTOR(S) Ansas Matthias Kasten (Niskayuna, New York);  Yuri Plotnikov (Chesterfield, Virginia);  Sudeep Mandal (Broussard, Louisiana);  Sarah Lillian Katz (Albany, New York);  Frederick Wheeler (Niskayuna, New York);  William Robert Ross (Rotterdam, New York);  John Scott Price (Niskayuna, New York)
ABSTRACT A downhole multi-modality inspection system includes a first imaging device operable to generate first imaging data and a second imaging device operable to generate second imaging data. The first imaging device includes a first source operable to emit energy of a first modality, and a first detector operable to detect returning energy induced by the emitted energy of the first modality. The second imaging device includes a second source operable to emit energy of a second modality, and a second detector operable to detect returning energy induced by the emitted energy of the second modality. The system further includes a processor configured to receive the first imaging data and the second imaging data, and integrate the first imaging data with the second imaging data into an enhanced data stream. The processor correlates the first imaging data and the second imaging data to provide enhanced data for detecting potential wellbore anomalies.
FILED Monday, August 13, 2018
APPL NO 16/102371
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 47/13 (20200501)
E21B 47/16 (20130101)
E21B 47/085 (20200501)
E21B 47/117 (20200501)
E21B 47/135 (20200501)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/44 (20130101)
G01V 3/30 (20130101)
G01V 5/10 (20130101)
G01V 5/107 (20130101) Original (OR) Class
G01V 5/145 (20130101)
G01V 8/16 (20130101)
G01V 11/00 (20130101)

Electric Digital Data Processing
G06F 17/15 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783464 Keene
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Lionel Keene (Livermore, California)
ABSTRACT An extended reality (“XR”) inspection system for inspecting a target is provided. The XR inspection system includes an inspection system and an XR device. The inspection system includes an inspection main unit and an inspection probe. The inspection main unit collects inspection data from the inspection probe, receives commands input by an inspector using the XR device, performs functions associated with the commands, and sends display data to the XR device. The XR device provides an augmented reality display and sensors. The XR device displays display data received from the inspection main unit, receives commands via the sensors from the inspector, and sends the commands to the inspection main unit.
FILED Friday, May 18, 2018
APPL NO 15/984204
ART UNIT 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0004 (20130101) Original (OR) Class
G06T 19/006 (20130101)

Image or Video Recognition or Understanding
G06V 20/20 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783518 Kim et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Hyojin Kim (Davis, California);  Rushil Anirudh (Dublin, California);  Kyle Champley (Pleasanton, California)
ABSTRACT A system for generating 2D slices of a 3D image of a target volume is provided. The system receives a target sinogram collected during a computed tomography scan of the target volume. The system inputs the target sinogram to a convolutional neural network (CNN) to generate predicted 2D slices of the 3D image. The CNN is trained using training 2D slices of training 3D images. The system initializes 2D slices to the predicted 2D slices. The system reconstructs 2D slices of the 3D image from the target sinogram and the initialized 2D slices.
FILED Wednesday, September 30, 2020
APPL NO 17/038565
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/032 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/045 (20230101)
G06N 3/088 (20130101)

Image Data Processing or Generation, in General
G06T 9/002 (20130101)
G06T 11/006 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783847 Sivaraman Narayanaswamy et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Arizona Board of Regents on Behalf of Arizona State Univesity (Tempe, Arizona)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona)
INVENTOR(S) Vivek Sivaraman Narayanaswamy (Tempe, Arizona);  Jayaraman Thiagarajan (Dublin, California);  Rushil Anirudh (San Francisco, California);  Andreas Spanias (Tempe, Arizona)
ABSTRACT Various embodiments of a system and associated method for audio source separation based on generative priors trained on individual sources. Through the use of projected gradient descent optimization, the present approach simultaneously searches in the source-specific latent spaces to effectively recover the constituent sources. Though the generative priors can be defined in the time domain directly, it was found that using spectral domain loss functions leads to good-quality source estimates.
FILED Wednesday, December 29, 2021
APPL NO 17/564502
ART UNIT 2651 — Videophones and Telephonic Communications
CURRENT CPC
Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 21/028 (20130101) Original (OR) Class
G10L 25/18 (20130101)
G10L 25/30 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 29/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783952 Perkins et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Lindsay John Perkins (Pleasanton, California);  Jim H. Hammer (Livermore, California);  John H. Moody (Livermore, California);  Max Tabak (Livermore, California);  Burl Grant Logan (Danville, California)
ABSTRACT Application of axial seed magnetic fields in the range 20-100 T that compress to greater than 10,000 T (100 MG) under typical NIF implosion conditions may significantly relax the conditions required for ignition and propagating burn in NIF ignition targets that are degraded by hydrodynamic instabilities. Such magnetic fields can: (a) permit the recovery of ignition, or at least significant alpha particle heating, in submarginal NIF targets that would otherwise fail because of adverse hydrodynamic instability growth, (b) permit the attainment of ignition in conventional cryogenic layered solid-DT targets redesigned to operate under reduced drive conditions, (c) permit the attainment of volumetric ignition in simpler, room-temperature single-shell DT gas capsules, and (d) ameliorate adverse hohlraum plasma conditions during laser drive and capsule compression. In general, an applied magnetic field should always improve the ignition condition for any NIF ignition target design.
FILED Tuesday, December 14, 2021
APPL NO 17/644292
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Fusion Reactors
G21B 1/03 (20130101)
G21B 1/05 (20130101) Original (OR) Class
G21B 1/19 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 30/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783954 Wang et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Yifeng Wang (Albuquerque, New Mexico);  David Louie (Albuquerque, New Mexico);  Rekha R. Rao (Albuquerque, New Mexico);  Jeremy A. Templeton (Castro Valley, California)
ABSTRACT Systems and methods for injecting a carbonate-based sacrificial material into a nuclear reactor containment for containment of molten corium in severe nuclear reactor accidents are disclosed. Molten corium can be quickly cooled and solidified by the endothermic decomposition of the sacrificial material.
FILED Monday, February 07, 2022
APPL NO 17/665719
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Nuclear Reactors
G21C 9/00 (20130101)
G21C 9/016 (20130101) Original (OR) Class
G21C 15/18 (20130101)
G21C 19/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783968 Takayasu et al.
FUNDED BY
Department of Energy (DOE)
Office of Scientific and Technical Information (OSTI)
Office of Science (DOE-SC)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Brookhaven Technology Group, Inc. (Stony Brook, New York)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Brookhaven Technology Group, Inc. (Glen Cove, New York)
INVENTOR(S) Makoto Takayasu (Lexington, Massachusetts);  Vyacheslav Solovyov (Rocky Point, New York)
ABSTRACT A structure and method provide cables of high-temperature superconducting flat tape and/or filament wires, with a small bending diameter. A cable has a former having cross section that includes a rectangle having rounded ends (i.e. an obround), and the flat tape is wound around the surface of the former at an angle to minimize bending. The former surface may have raised helical ribs or lowered grooves to provide tape registration in multi-layer configurations. Tape may be wound from a spool onto the former under tension, and cut with a laser cutter to produce fine filaments immediately before winding. The former may be slit longitudinally to prevent loop eddy currents and reduce AC losses. The wound cable may be jacketed to provide a cable-in-conduit conductor (CICC), and coolant channels may be provided in the jacket or in the former.
FILED Friday, April 30, 2021
APPL NO 17/245863
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 12/06 (20130101)
H01B 12/08 (20130101) Original (OR) Class
H01B 12/16 (20130101)
H01B 13/282 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783996 Pratt et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Richard M. Pratt (Richland, Washington);  Michael CW Kintner-Meyer (Richland, Washington)
ABSTRACT Transformer power management controllers and transformer power management methods are described. According to one aspect, a transformer power management controller includes processing circuitry configured to monitor an electrical characteristic of electrical energy which is received from a secondary of a transformer of an electric power system, use the monitored electrical characteristic to determine transformer loading information which is indicative of an amount of power which is being supplied by the secondary of the transformer to a plurality of loads which are coupled with the secondary of the transformer, and use the transformer loading information to adjust an amount of the electrical energy which is supplied by the secondary of the transformer to at least one of the loads which is coupled with the secondary of the transformer.
FILED Wednesday, June 06, 2018
APPL NO 16/001465
ART UNIT 2119 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Systems for Regulating Electric or Magnetic Variables
G05F 1/14 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 27/402 (20130101) Original (OR) Class
H01F 2027/406 (20130101)

Emergency Protective Circuit Arrangements
H02H 7/04 (20130101)

Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils
H02P 13/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784350 Zhang et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Zhengcheng Zhang (Naperville, Illinois);  Qian Liu (Darien, Illinois)
ABSTRACT The ionic liquids disclosed herein are salts comprising a nitrogen or phosphorus such as a quaternary ammonium ion, a quaternary phosphonium ion, or an N-alkylated nitrogen heterocycle, and which include at least one functional substituent, e.g., a fluoro, cyano, carbonate ester, an alkenyl group, or an alkynyl group bonded to a carbon atom the cation. In a preferred embodiment, the cation is represented by the structure of Formula (I) as described herein.
FILED Friday, December 20, 2019
APPL NO 16/722413
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 207/06 (20130101)
C07D 207/10 (20130101)
C07D 211/14 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0525 (20130101)
H01M 10/0569 (20130101) Original (OR) Class
H01M 2300/0028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784616 Chang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California);  SoCal Simulations, LLC (Sacramento, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  SOCAL SIMULATIONS, LLC (Sacramento, California)
INVENTOR(S) Tammy Chang (San Ramon, California);  Adam Conway (Livermore, California);  Victor Valeryevich Khitrov (San Ramon, California);  Lars Voss (Livermore, Idaho);  Benjamin Fasenfest (Redding, California);  Peter Asbeck (Del Mar, California)
ABSTRACT Power amplifier apparatuses and techniques for optimizing the design of power amplifiers are disclosed. In one aspect, a method for optimizing a power amplifier includes selecting a circuit topology for the power amplifier. The circuit topology includes one or more photoconductive switches and an impedance matching network including one or more parameter values representative of the impedance matching network or the photoconductive switches that can be adjusted. The method further includes selecting one or more optimization goals for the impedance matching network and the one or more photoconductive switches, and adjusting the one or more parameter values according to the one or more optimization goals. The one or more optimization goals include an efficiency at a particular power output.
FILED Tuesday, March 16, 2021
APPL NO 17/202691
ART UNIT 2843 — Electrical Circuits and Systems
CURRENT CPC
Amplifiers
H03F 1/565 (20130101)
H03F 3/195 (20130101)
H03F 3/245 (20130101) Original (OR) Class
H03F 2200/318 (20130101)
H03F 2200/421 (20130101)
H03F 2200/423 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784920 Roweth et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Spring, Texas)
INVENTOR(S) Duncan Roweth (Bristol, United Kingdom);  Edwin L. Froese (Burnaby, Canada);  Joseph G. Kopnick (Chippewa Falls, Wisconsin);  Andrew S. Kopser (Seattle, Washington);  Robert Alverson (Seattle, Washington)
ABSTRACT Systems and methods are provided for passing data amongst a plurality of switches having a plurality of links attached between the plurality of switches. At a switch, a plurality of load signals are received from a plurality of neighboring switches. Each of the plurality of load signals are made up of a set of values indicative of a load at each of the plurality of neighboring switches providing the load signal. Each value within the set of values provides an indication for each link of the plurality of links attached thereto as to whether the link is busy or quiet. Based upon the plurality of load signals, an output link for routing a received packet is selected, and the received packet is routed via the selected output link.
FILED Monday, March 23, 2020
APPL NO 17/594736
ART UNIT 2419 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Electric Digital Data Processing
G06F 9/505 (20130101)
G06F 9/546 (20130101)
G06F 12/0862 (20130101)
G06F 12/1036 (20130101)
G06F 12/1063 (20130101)
G06F 13/14 (20130101)
G06F 13/16 (20130101)
G06F 13/385 (20130101)
G06F 13/1642 (20130101)
G06F 13/1673 (20130101)
G06F 13/1689 (20130101)
G06F 13/4022 (20130101)
G06F 13/4068 (20130101)
G06F 13/4221 (20130101)
G06F 15/17331 (20130101)
G06F 2212/50 (20130101)
G06F 2213/0026 (20130101)
G06F 2213/3808 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0083 (20130101)
H04L 43/10 (20130101)
H04L 43/0876 (20130101)
H04L 45/16 (20130101)
H04L 45/20 (20130101)
H04L 45/021 (20130101)
H04L 45/22 (20130101)
H04L 45/24 (20130101)
H04L 45/028 (20130101)
H04L 45/28 (20130101) Original (OR) Class
H04L 45/38 (20130101)
H04L 45/42 (20130101)
H04L 45/46 (20130101)
H04L 45/70 (20130101)
H04L 45/122 (20130101)
H04L 45/123 (20130101)
H04L 45/125 (20130101)
H04L 45/566 (20130101)
H04L 45/745 (20130101)
H04L 45/7453 (20130101)
H04L 47/11 (20130101)
H04L 47/12 (20130101)
H04L 47/18 (20130101)
H04L 47/20 (20130101)
H04L 47/22 (20130101)
H04L 47/24 (20130101)
H04L 47/30 (20130101)
H04L 47/32 (20130101)
H04L 47/34 (20130101)
H04L 47/39 (20130101)
H04L 47/52 (20130101)
H04L 47/76 (20130101)
H04L 47/80 (20130101)
H04L 47/122 (20130101)
H04L 47/323 (20130101)
H04L 47/621 (20130101)
H04L 47/626 (20130101)
H04L 47/629 (20130101)
H04L 47/762 (20130101)
H04L 47/781 (20130101)
H04L 47/2441 (20130101)
H04L 47/2466 (20130101)
H04L 47/2483 (20130101)
H04L 47/6235 (20130101)
H04L 47/6275 (20130101)
H04L 49/15 (20130101)
H04L 49/30 (20130101)
H04L 49/90 (20130101)
H04L 49/101 (20130101)
H04L 49/3009 (20130101)
H04L 49/3018 (20130101)
H04L 49/3027 (20130101)
H04L 49/9005 (20130101)
H04L 49/9021 (20130101)
H04L 49/9036 (20130101)
H04L 49/9047 (20130101)
H04L 67/1097 (20130101)
H04L 69/22 (20130101)
H04L 69/28 (20130101)
H04L 69/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11785850 Ren et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) University of Houston System (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S) Zhifeng Ren (Pearland, Texas);  Hangtian Zhu (Houston, Texas)
ABSTRACT A method of thermoelectric power generation by converting heat to electricity via the use of a ZrCoBi-based thermoelectric material, wherein a thermoelectric conversion efficiency of the ZrCoBi-based thermoelectric material is greater than or equal to 7% at a temperature difference of up to 800 K.
FILED Thursday, June 09, 2022
APPL NO 17/836072
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Electric solid-state devices not otherwise provided for
H10N 10/80 (20230201)
H10N 10/853 (20230201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11779230 Mukkamala et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan);  University of Maryland (College Park, Maryland)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Ramakrishna Mukkamala (Okemos, Michigan);  Keerthana Natarajan (East Lansing, Michigan);  Jin-Oh Hahn (Rockville, Maryland)
ABSTRACT Current oscillometric devices for monitoring central blood pressure (BP) maintain the cuff pressure at a constant level to acquire a pulse volume plethysmography (PVP) waveform and calibrate it to brachial BP levels estimated with population average methods. A physiologic method was developed to further advance central BP measurement. A patient-specific method was applied to estimate brachial BP levels from a cuff pressure waveform obtained during conventional deflation via a nonlinear arterial compliance model. A physiologically-inspired method was then employed to extract the PVP waveform from the same waveform via ensemble averaging and calibrate it to the brachial BP levels. A method based on a wave reflection model was thereafter employed to define a variable transfer function, which was applied to the calibrated waveform to derive central BP.
FILED Thursday, July 12, 2018
APPL NO 16/629403
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/02225 (20130101) Original (OR) Class
A61B 5/7235 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779422 Zhao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Xuanhe Zhao (Allston, Massachusetts);  Yoonho Kim (Cambridge, Massachusetts)
ABSTRACT Robotic devices and methods for performing minimally invasive procedures on the vascular system, particularly cerebrovascular and endovascular neurosurgical procedures, where a submillimeter-scale continuum robotic device is configured and adapted for active steering and navigation based on external magnetic actuation. The submillimeter-scale continuum robotic device includes an elongate body having an inner core and an outer shell, where the outer shell is fabricated of an elastomeric material having a plurality of ferromagnetic particles dispersed therein.
FILED Thursday, August 26, 2021
APPL NO 17/458114
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/203 (20130101)
A61B 34/20 (20160201)
A61B 34/30 (20160201)
A61B 34/71 (20160201)
A61B 34/73 (20160201) Original (OR) Class
A61B 2018/00577 (20130101)
A61B 2034/731 (20160201)
A61B 2034/2061 (20160201)
A61B 2090/306 (20160201)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1682 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779466 Hoelzle
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of Notre Dame du LAC (South Bend, Indiana)
ASSIGNEE(S) University of Notre Dame du LAC (South Bend, Indiana)
INVENTOR(S) David J. Hoelzle (Columbus, Ohio)
ABSTRACT An additive manufacturing (AM) device for biomaterials comprises a reservoir, a shaft, and a material delivery head. The device can be used for intracorporeal additive manufacturing. Material within the reservoir can be expelled by a mechanical transmission element, for example a syringe pump, a peristaltic pump, an air pressure pump, or a hydraulic pressure pump. The reservoir can be a barrel, a cartridge, or a cassette. The reservoir can narrow into the shaft, and the shaft can terminate into the nozzle. The shaft can house an inner tube. The device can have an actuator joint capable of being mechanically linked to a robotic surgical system. The actuator joint can have a motor that drives the mechanical transmission element.
FILED Thursday, December 03, 2020
APPL NO 17/110973
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/08 (20130101)
A61F 2/30756 (20130101) Original (OR) Class
A61F 2/30942 (20130101)
A61F 2002/0894 (20130101)
A61F 2002/30962 (20130101)
A61F 2002/30985 (20130101)
A61F 2240/002 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/118 (20170801)
B29C 64/209 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2995/0056 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/7532 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779542 Murphy et al.
FUNDED BY
Environmental Protection Agency (EPA)
National Science Foundation (NSF)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) William L. Murphy (Waunakee, Wisconsin);  Andrew Salim Khalil (Madison, Wisconsin);  Xiaohua Yu (Mansfield Center, Connecticut)
ABSTRACT Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonucleic acid, and an interferon binding protein. Ribonucleic acids and interferon binding proteins can be adsorbed to the mineral layer, can be incorporated into the mineral Layer, and combinations thereof. Also disclosed are methods for co-delivery of ribonucleic acids and interferon binding proteins and methods for treating inflammatory diseases using mineral coated microparticles having a mineral layer to provide co-delivery of ribonucleic acids and interferon binding proteins.
FILED Monday, July 19, 2021
APPL NO 17/379351
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/501 (20130101) Original (OR) Class
A61K 38/162 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/88 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779646 DeForest et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) UNIVERSITY OF WASHINGTON (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Cole Alexander DeForest (Seattle, Washington);  Jared Shadish (Seattle, Washington);  Luman Liu (Seattle, Washington)
ABSTRACT The present disclosure features a protein-polymer conjugate, including a multivalent polymer building block, a stimuli-responsive protein covalently conjugated to the multivalent polymer building block to provide a protein-polymer conjugate, wherein the protein undergoes a modification upon exposure to a predetermined stimulus, and the protein modification triggers a physical and/or chemical response in the protein-polymer conjugate.
FILED Tuesday, April 30, 2019
APPL NO 16/399882
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/74 (20130101)
A61K 41/0042 (20130101)
A61K 47/58 (20170801) Original (OR) Class
A61K 47/593 (20170801)
A61K 47/6903 (20170801)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 31/145 (20130101)

Peptides
C07K 1/1136 (20130101)
C07K 17/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779647 Jeffries et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Eric M. Jeffries (West New York, New Jersey);  Yadong Wang (Bradford Woods, Pennsylvania)
ABSTRACT Provided herein are coacervate compositions including cytokines, and methods of making and using the same. The coacervate can be formed by the mixing of an active agent, such as a drug or protein with the polyanion, such as heparin or heparan sulfate, and a custom-made polycation (e.g., PEAD or PELD). The coacervates can be used in the treatment of diseases and disorders where targeted treatment is desired, for example in treatment of cancers.
FILED Friday, June 04, 2021
APPL NO 17/339373
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/08 (20130101)
A61K 9/10 (20130101)
A61K 9/0019 (20130101)
A61K 31/727 (20130101)
A61K 38/18 (20130101)
A61K 38/18 (20130101)
A61K 38/20 (20130101)
A61K 38/20 (20130101)
A61K 38/21 (20130101)
A61K 38/21 (20130101)
A61K 38/208 (20130101)
A61K 38/208 (20130101)
A61K 38/1825 (20130101)
A61K 38/1825 (20130101)
A61K 38/2066 (20130101)
A61K 38/2066 (20130101)
A61K 47/34 (20130101)
A61K 47/36 (20130101)
A61K 47/58 (20170801) Original (OR) Class
A61K 47/61 (20170801)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779682 Gerecht et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Sharon Gerecht (Severna Park, Maryland);  Shuming Zhang (Lehigh Acres, Florida);  Sebastian F. Barreto Ortiz (Baltimore, Texas);  Hai-Quan Mao (Baltimore, Maryland)
ABSTRACT The presently disclosed subject matter provides a scalable and electrostretching approach for generating hydrogel microfibers exhibiting uniaxial alignment from aqueous polymer solutions. Such hydrogel microfibers can be generated from a variety of water-soluble natural polymers or synthetic polymers. The hydrogel microfibers can be used for controlled release of bioactive agents. The internal uniaxial alignment exhibited by the presently disclosed hydrogel fibers provides improved mechanical properties to hydrogel microfibers, and contact guidance cues and induces alignment for cells seeded on or within the hydrogel microfibers.
FILED Friday, October 05, 2018
APPL NO 16/152556
ART UNIT 1786 — Miscellaneous Articles, Stock Material
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/52 (20130101) Original (OR) Class
A61L 27/58 (20130101)
A61L 27/225 (20130101)
A61L 27/3633 (20130101)
A61L 27/3808 (20130101)
A61L 27/3826 (20130101)
A61L 27/3886 (20130101)
A61L 2400/12 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/29 (20150115)
Y10T 428/2913 (20150115)
Y10T 428/2922 (20150115)
Y10T 428/2938 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779927 Moon et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Hyejin Moon (Euless, Texas);  Matin Torabinia (Arlington, Texas)
ABSTRACT A method of moving a solvent without electrowetting properties on an electro-wetting-on-dielectric (EWOD) microfluidic device comprises disposing a first droplet of a first fluid having electrowetting properties on a surface of the EWOD microfluidic device; disposing a second droplet of a second fluid without electrowetting properties on the surface; applying a voltage to the surface to move the first droplet towards the second droplet; contacting the first droplet with the second droplet to form a encapsulated droplet, where the second droplet encapsulates the first droplet.
FILED Monday, July 13, 2020
APPL NO 16/926947
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50273 (20130101)
B01L 3/502792 (20130101) Original (OR) Class
B01L 2200/0673 (20130101)
B01L 2300/0645 (20130101)
B01L 2300/0819 (20130101)
B01L 2400/0427 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779938 Sethi
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) HEN Nozzles Inc. (Castro Valley, California)
ASSIGNEE(S) HEN NOZZLES, INC. (Castro Valley, California)
INVENTOR(S) Sunny Sethi (Castro Valley, California)
ABSTRACT A high efficiency nozzle is designed. The nozzle allows water streams with long-range and high surface area in one system. Suitable transitions in the fluid pathways allow creating water streams that have a robust flow profile. The system allows minimum energy loss whilst maximizing the velocity and surface area. Such nozzles can be used for a variety of applications including but not limited to fire suppression, pressure washing, watering, and other such applications.
FILED Saturday, December 05, 2020
APPL NO 17/112993
ART UNIT 3752 — Fluid Handling and Dispensing
CURRENT CPC
Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 1/02 (20130101)
B05B 1/06 (20130101) Original (OR) Class
B05B 1/044 (20130101)
B05B 1/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780829 Thompson et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The University of Southern California (Los Angeles, California)
ASSIGNEE(S) The University of Southern California (Los Angeles, California)
INVENTOR(S) Mark E. Thompson (Anaheim, California);  Abegail Tadle (Bakersfield, California);  Karim El Roz (Los Angeles, California);  Peter Ivan Djurovich (Long Beach, California);  Daniel Sylvinson Muthiah Ravinson (Los Angeles, California);  Jessica H. Golden (Berkeley, California);  Stuart W. Sawyer (South Hampton, United Kingdom)
ABSTRACT A compound of Formula X wherein ring A is absent, or present and selected from a 5-membered or 6-membered, carbocyclic or heterocyclic ring, which is optionally substituted; ring B is absent, or present and selected from a 5-membered or 6-membered, carbocyclic or heterocyclic ring, which is optionally substituted; and at least one of ring A or ring B is present, and the hash line represents ring A fused to ring N—W1—W3 and ring B fused to ring N—W4—W6; W1, W2, W3, W4, W5, and W6 are independently selected from CR1 or N; Z is selected from CRZ or N; and Y is selected from a group consisting of C(R2)2, B(R2)2, Al(R2)2, Si(R2)2, and Ge(R2)2. An optoelectronic device selected from the group consisting of a photovoltaic device, a photodetector device, a photosensitive device, and an OLED, the optoelectronic device including an organic layer that comprises a compound of Formula X. A consumer product that includes the optoelectronic device.
FILED Thursday, January 16, 2020
APPL NO 16/744728
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 209/82 (20130101)
C07D 251/24 (20130101)
C07D 333/54 (20130101)
C07D 403/04 (20130101)
C07D 403/14 (20130101)
C07D 405/14 (20130101) Original (OR) Class
C07D 409/14 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/0812 (20130101)

Organic electric solid-state devices
H10K 85/40 (20230201)
H10K 85/622 (20230201)
H10K 85/6572 (20230201)
H10K 85/6574 (20230201)
H10K 85/6576 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780861 McNally et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado)
ASSIGNEE(S) Colorado State University Research Foundation (Fort Collins, Colorado)
INVENTOR(S) Andrew McNally (Fort Collins, Colorado);  Kyle Nottingham (Fort Collins, Colorado);  Chirag Patel (Fort Collins, Colorado);  Jeffrey Levy (Fort Collins, Colorado);  Xuan Zhang (Fort Collins, Colorado)
ABSTRACT A new set of bench-stable fluoroalkylphosphines that directly convert C—H bonds in pyridine building blocks, drug-like fragments, and pharmaceuticals, into fluoroalkyl derivatives. No pre-installed functional groups or directing motifs are required. The reaction tolerates a variety of sterically and electronically distinct pyridines and is exclusively selective for the 4-position in most cases. The reaction proceeds via initial phosphonium salt formation followed by sp2-sp3 phosphorus ligand-coupling, an underdeveloped manifold for C—C bond formation.
FILED Wednesday, October 20, 2021
APPL NO 17/634140
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 47/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/572 (20130101) Original (OR) Class
C07F 9/5022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780950 Stewart et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Novol, Inc. (San Leandro, California)
ASSIGNEE(S) Monica Bhatia (San Ramon, California)
INVENTOR(S) Ray F. Stewart (San Leandro, California);  Monica Bhatia (San Leandro, California);  Jagdish Jethmalani (San Leandro, California);  Sanjiban Chakraborty (San Leandro, California)
ABSTRACT The present invention is based, in part, on the discovery that the polymeric materials described herein produce polyurethane copolymers with advantageous optical properties. In particular embodiments, polyurethane copolymers comprise repeating units of isosorbide and a difunctional linker where the difunctional linkers can be diisocyanate, diisothiocyanate, dicarboxylic acid, and other monomers. Some of the advantageous optical properties of these polymeric materials include a refractive index of about 1.5 and an Abbe value of at least about 50. Also described are methods for producing these polyurethane copolymers.
FILED Friday, May 01, 2020
APPL NO 16/864681
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 493/04 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/73 (20130101)
C08G 18/3218 (20130101) Original (OR) Class
C08G 18/7664 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/041 (20130101)
G02B 1/045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781149 Khalil et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Ahmad S. Khalil (Lexington, Massachusetts);  Caleb J. Bashor (Boston, Massachusetts);  Nikit Patel (Brookline, Massachusetts);  James J. Collins (Newton, Massachusetts)
ABSTRACT Embodiments disclosed herein provide artificial expression systems comprising multivalent transcription factor complexes for cooperative transcription factor assembly and modulating gene expression. More specifically, engineered synthetic transcription factors are recruited and structurally organized on synthetic gene circuits using molecular clamps, where the strength of intra-complex interactions can be modulated for fine tuning of gene expression as desired.
FILED Friday, June 28, 2019
APPL NO 16/456556
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/47 (20130101)
C07K 2319/81 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8216 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781199 Manuel et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  UTBATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Michele Viola Manuel (Gainesville, Florida);  Hunter B. Henderson (Gainesville, Florida);  Orlando Rios (Oak Ridge, Tennessee);  Gerard M. Ludtka (Oak Ridge, Tennessee)
ABSTRACT Disclosed herein is a method comprising disposing a container containing a metal and/or ferromagnetic solid and abrasive particles in a static magnetic field; where the container is surrounded by an induction coil; activating the induction coil with an electrical current, to heat up the metallic or ferromagnetic solid to form a fluid; generating sonic energy to produce acoustic cavitation and abrasion between the abrasive particles and the container; and producing nanoparticles that comprise elements from the container, the metal and/or the ferromagnetic solid and the abrasive particles. Disclosed herein too is a composition comprising first metal or a first ceramic; and particles comprising carbides and/or nitrides dispersed therein. Disclosed herein too is a composition comprising nanoparticles comprising chromium carbide, iron carbide, nickel carbide, γ-Fe and magnesium nitride.
FILED Thursday, February 23, 2023
APPL NO 18/173158
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/00 (20130101)
B22F 1/07 (20220101)
B22F 1/12 (20220101)
B22F 1/054 (20220101)
B22F 9/04 (20130101)
B22F 9/06 (20130101)
B22F 2009/042 (20130101)
B22F 2009/045 (20130101)
B22F 2202/01 (20130101)
B22F 2202/05 (20130101)
B22F 2202/07 (20130101)
B22F 2301/058 (20130101)
B22F 2302/10 (20130101)
B22F 2302/20 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Alloys
C22C 1/1084 (20130101) Original (OR) Class
C22C 1/1084 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 1/00 (20130101)
C25D 15/00 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/0036 (20130101)
H01F 1/047 (20130101)
H01F 1/442 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 6/367 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781307 Bertoldi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Katia Bertoldi (Cambridge, Massachusetts);  Matheus C. Fernandes (Arlington, Massachusetts);  James C. Weaver (Cambridge, Massachusetts)
ABSTRACT A structural lattice includes a rectangular base defined by four periphery beams, and two non-diagonal beams that divide the rectangular base in four quadrants. The structural lattice further includes a diagonal reinforcement strut system overlaid on the rectangular base and having at least two intersecting sets of diagonal beams forming an open-and-closed cell architecture.
FILED Wednesday, November 27, 2019
APPL NO 17/309475
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings
E04B 1/19 (20130101) Original (OR) Class

Structural Elements; Building Materials
E04C 3/08 (20130101)
E04C 3/083 (20130101)
E04C 5/06 (20130101)
E04C 2003/026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781379 Zhang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Xiaosheng Zhang (Berkeley, California);  Ming Chiang A Wu (Moraga, California);  Andrew S Michaels (Berkeley, California);  Johannes Henriksson (Berkeley, California)
ABSTRACT An integrated-optics MEMS-actuated beam-steering system is disclosed, wherein the beam-steering system includes a lens and a programmable vertical coupler array having a switching network and an array of vertical couplers, where the switching network can energize of the vertical couplers such that it efficiently emits the light into free-space. The lens collimates the light received from the energized vertical coupler and directs the output beam along a propagation direction determined by the position of the energized vertical coupler within the vertical-coupler array. In some embodiments, the vertical coupler is configured to correct an aberration of the lens. In some embodiments, more than one vertical coupler can be energized to enable steering of multiple output beams. In some embodiments, the switching network is non-blocking.
FILED Thursday, July 14, 2022
APPL NO 17/865131
ART UNIT 2874 — Optics
CURRENT CPC
Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates
E06B 9/34 (20130101)
E06B 9/42 (20130101)
E06B 9/80 (20130101) Original (OR) Class
E06B 9/325 (20130101)
E06B 9/326 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/292 (20130101)
G02F 1/3132 (20130101)
G02F 1/3137 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781984 Koide et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Kazunori Koide (Pittsburgh, Pennsylvania);  Melissa L. Campbell (Pittsburgh, Pennsylvania);  Dianne Pham (Pittsburgh, Pennsylvania)
ABSTRACT Methods of detecting platinum and copper in a test sample are provided. Kits for use in detecting platinum and copper in a test sample also are provided.
FILED Monday, May 09, 2022
APPL NO 17/739579
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/643 (20130101)
G01N 21/6428 (20130101) Original (OR) Class
G01N 33/20 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 436/16 (20150115)
Y10T 436/18 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781986 Tropp et al.
FUNDED BY
National Science Foundation (NSF)
Office of The Director (OD)
Office of Integrative Activities (OIA)
APPLICANT(S) Joshua Tropp (Hattiesburg, Mississippi);  Jason D. Azoulay (Hattiesburg, Mississippi)
ASSIGNEE(S) University of Southern Mississippi (Hattiesburg, Mississippi)
INVENTOR(S) Joshua Tropp (Hattiesburg, Mississippi);  Jason D. Azoulay (Hattiesburg, Mississippi)
ABSTRACT The methods disclosed utilize π-conjugated polymers (CPs) as sensors for various analytes through the inner filter effect (IFE). Further, the methods utilize CPs with controlled optical properties for targeting sensing applications and operates through a novel IFE-based method, providing sensitive and selective sensors that operate in complex environments. The methods further provide calibration standards for the identification of similar and structurally distinct target analytes, where the analyte is a small molecule, macromolecule, and/or biological organism of interest.
FILED Thursday, December 31, 2020
APPL NO 17/139707
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/645 (20130101) Original (OR) Class

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/70 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781993 Leo et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Sin Yen Leo (Gainesville, Florida);  Peng Jiang (Gainesville, Florida);  Tianwei Xie (Gainesville, Florida)
ABSTRACT Embodiments of the present disclosure provide for methods of detecting, sensors (e.g., chromogenic sensor), kits, compositions, and the like that related to or use tunable macroporous polymer. In an aspect, tunable macroporous materials as described herein can be used to determine the presence of a certain type(s) and quantity of liquid in a liquid mixture.
FILED Tuesday, September 06, 2022
APPL NO 17/903312
ART UNIT 1758 — Optics
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/81 (20130101)
C08G 18/6755 (20130101)
C08G 2101/00 (20130101)
C08G 2280/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/26 (20130101)
C08J 2201/0442 (20130101)
C08J 2205/044 (20130101)
C08J 2375/14 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/25 (20130101)
G01N 21/78 (20130101) Original (OR) Class
G01N 21/255 (20130101)
G01N 21/272 (20130101)
G01N 33/2852 (20130101)
G01N 2021/7723 (20130101)
G01N 2021/7773 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782064 Linghu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Changyang Linghu (Cambridge, Massachusetts);  Shannon L. Johnson (Cambridge, Massachusetts);  Edward Stuart Boyden (Chestnut Hill, Massachusetts)
ABSTRACT The invention, in some aspects, relates to the preparation and use of signaling reporter islands (SiRIs) in single cells. Compositions of the invention that produce SiRIs can be delivered to a cell resulting in the presence of one or more SiRIs in the cell. Methods of the invention include detecting signals generated by elements in the SiRIs in a cell and use of the detected signals to determine and analyze simultaneous physiological processes within the cell, or cells.
FILED Monday, September 14, 2020
APPL NO 17/020803
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/705 (20130101)
C07K 2319/01 (20130101)
C07K 2319/60 (20130101)
C07K 2319/735 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/10 (20130101)
C12N 15/62 (20130101)
C12N 15/63 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
G01N 33/5005 (20130101)
G01N 33/6872 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782779 Albert et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Victor V. Albert (New Haven, Connecticut);  Shantanu Mundhada (New Haven, Connecticut);  Alexander Grimm (New Haven, Connecticut);  Steven Touzard (New Haven, Connecticut);  Michel Devoret (New Haven, Connecticut);  Liang Jiang (Guilford, Connecticut)
ABSTRACT Techniques for quantum error correction of a multi-level system are provided and described. In some aspects, techniques for encoding a state of a multi-level quantum system include encoding a quantum information in a two-mode state of two quantum mechanical oscillators. Techniques for protecting the two-mode state against dephasing and energy loss are described.
FILED Saturday, January 05, 2019
APPL NO 16/959209
ART UNIT 2896 — Optics
CURRENT CPC
Electric Digital Data Processing
G06F 11/0736 (20130101)
G06F 11/0751 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)
G06N 10/70 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783060 Jha
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Niraj K. Jha (Princeton, New Jersey)
ABSTRACT Devices and methods for processing detected signals at a detector using a processor are provided. The system involves (i) a data compressor that implements an algorithm for converting a set of data into a compressed set of data, (ii) a machine learning (ML) module coupled to the data compressor, the ML module transforming the compressed set of data into a vector and filtering the vector, (iii) a data encryptor coupled to the ML module that encrypts the filtered vector, and (iv) an integrity protection module coupled to the ML module, wherein the integrity protection module protects the integrity of the filtered vector.
FILED Wednesday, January 24, 2018
APPL NO 16/479714
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 12/14 (20130101)
G06F 21/606 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 3/08 (20130101)
G06N 20/10 (20190101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3239 (20130101)
H04L 69/04 (20130101)
H04L 2209/72 (20130101)

Wireless Communication Networks
H04W 4/38 (20180201)
H04W 12/03 (20210101)
H04W 12/42 (20210101)
H04W 12/106 (20210101)
H04W 84/18 (20130101)

Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use
Y02D 30/70 (20200801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783847 Sivaraman Narayanaswamy et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Arizona Board of Regents on Behalf of Arizona State Univesity (Tempe, Arizona)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona)
INVENTOR(S) Vivek Sivaraman Narayanaswamy (Tempe, Arizona);  Jayaraman Thiagarajan (Dublin, California);  Rushil Anirudh (San Francisco, California);  Andreas Spanias (Tempe, Arizona)
ABSTRACT Various embodiments of a system and associated method for audio source separation based on generative priors trained on individual sources. Through the use of projected gradient descent optimization, the present approach simultaneously searches in the source-specific latent spaces to effectively recover the constituent sources. Though the generative priors can be defined in the time domain directly, it was found that using spectral domain loss functions leads to good-quality source estimates.
FILED Wednesday, December 29, 2021
APPL NO 17/564502
ART UNIT 2651 — Videophones and Telephonic Communications
CURRENT CPC
Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 21/028 (20130101) Original (OR) Class
G10L 25/18 (20130101)
G10L 25/30 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 29/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783875 Seok et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Mingoo Seok (Tenafly, New Jersey);  Zhewei Jiang (Oakland Gardens, New York);  Jae-sun Seo (Tempe, Arizona);  Shihui Yin (Mesa, Arizona)
ABSTRACT In some embodiments, an in-memory-computing SRAM macro based on capacitive-coupling computing (C3) (which is referred to herein as “C3SRAM”) is provided. In some embodiments, a C3SRAM macro can support array-level fully parallel computation, multi-bit outputs, and configurable multi-bit inputs. The macro can include circuits embedded in bitcells and peripherals to perform hardware acceleration for neural networks with binarized weights and activations in some embodiments. In some embodiments, the macro utilizes analog-mixed-signal capacitive-coupling computing to evaluate the main computations of binary neural networks, binary-multiply-and-accumulate operations. Without needing to access the stored weights by individual row, the macro can assert all of its rows simultaneously and form an analog voltage at the read bitline node through capacitive voltage division, in some embodiments. With one analog-to-digital converter (ADC) per column, the macro cab realize fully parallel vector-matrix multiplication in a single cycle in accordance with some embodiments.
FILED Tuesday, May 31, 2022
APPL NO 17/828964
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Electric Digital Data Processing
G06F 7/501 (20130101)
G06F 7/5443 (20130101)

Static Stores
G11C 7/1036 (20130101) Original (OR) Class
G11C 7/1051 (20130101)
G11C 7/1078 (20130101)
G11C 15/04 (20130101)
G11C 15/043 (20130101)
G11C 16/3404 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783986 Kyaw et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Phyo Aung Kyaw (West Lebanon, New Hampshire);  Aaron Stein (West Lebanon, New Hampshire);  Charles R. Sullivan (West Lebanon, New Hampshire)
ABSTRACT A resonant coil with integrated capacitance includes at least one separation dielectric layer and a plurality of conductor layers stacked in an alternating manner. Each of the plurality of conductor layers includes a first conductor sublayer and second conductor sublayer having common orientation and a sublayer dielectric layer separating the first and second conductor sublayers, each conductor layer having multiple discontinuities.
FILED Friday, August 14, 2020
APPL NO 16/994448
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 17/0013 (20130101)
H01F 17/062 (20130101) Original (OR) Class
H01F 38/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784316 Xia et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Younan Xia (Atlanta, Georgia);  Shuifen Xie (Fujian, China PRC);  Sang-Il Choi (Atlanta, Georgia);  Xue Wang (Atlanta, Georgia);  Jinho Park (Atlanta, Georgia);  Lei Zhang (Fujian, China PRC)
ABSTRACT Core-shell nanostructures with platinum overlayers conformally coating palladium nano-substrate cores and facile solution-based methods for the preparation of such core-shell nanostructures are described herein. The obtained Pd@Pt core-shell nanocatalysts showed enhanced specific and mass activities towards oxygen reduction, compared to a commercial Pt/C catalyst.
FILED Monday, August 02, 2021
APPL NO 17/391757
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/42 (20130101)
B01J 23/44 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 7/005 (20130101)
C30B 7/14 (20130101)
C30B 29/02 (20130101)
C30B 29/60 (20130101)
C30B 29/66 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/92 (20130101)
H01M 4/8657 (20130101) Original (OR) Class
H01M 2008/1095 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11785069 Liu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Research Foundation for The State University of New York (Binghamton, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Binghamton, New York)
INVENTOR(S) Yao Liu (Vestal, New York);  Shuoqian Wang (Vestal, New York)
ABSTRACT SphericRTC provides real-time 360-degree video communication, which allows the viewer to observe the environment in any direction from the camera location. This more allows users to more-efficiently exchange information and can be beneficial in the real-time setting. The system selects representations of 360-degree frames to allow efficient, content-adaptive delivery. The system performs joint content and bitrate adaptation in real-time by offloading expensive transformation operations to a GPU. The system demonstrates that the multiple sub-components: viewport feedback, representation selection, and joint content and bitrate adaptation, can be effectively integrated within a single framework. Compared to a baseline implementation, views in SphericRTC have consistently higher visual quality. The median Viewport-PSNR of such views is 2.25 dB higher than views in the baseline system.
FILED Monday, October 04, 2021
APPL NO 17/449893
ART UNIT 2651 — Videophones and Telephonic Communications
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 65/65 (20220501)
H04L 65/75 (20220501) Original (OR) Class

Pictorial Communication, e.g Television
H04N 23/698 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11785430 Zhu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S) Research Foundation of the City University of New York (New York, New York)
INVENTOR(S) Zhigang Zhu (Princeton, New York);  Jin Chen (New York, New York);  Hao Tang (New York, New York);  Arber Ruci (Ridgewood, New York)
ABSTRACT An indoor navigation system comprises a modeling subsystem that processes multimodal data regarding a location, individually generates a model of each of a plurality of overlapping local regions subdivided from the location, and maps the model of each region and a coordinate system of the model aligned with a floor plan of the location, and a navigation subsystem that processes the model to plot a path at the location for navigating a user along the path in real-time.
FILED Wednesday, August 11, 2021
APPL NO 17/399457
ART UNIT 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/206 (20130101)

Wireless Communication Networks
H04W 4/029 (20180201)
H04W 4/33 (20180201) Original (OR) Class
H04W 4/80 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11779869 Weislogel et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) IRPI LLC (Wilsonville, Oregon);  The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) IRPI LLC (Wilsonville, Oregon);  The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Mark M. Weislogel (Wilsonville, Oregon);  John C. Graf (Houston, Texas);  Nora D. Shapiro (Tempe, Arizona);  Logan Torres (Wilsonville, Oregon);  Rawand M. Rasheed (Houston, Texas);  Ryan Jenson (Wilsonville, Oregon)
ABSTRACT Methods and systems are provided for a multiplexed phase separating inertial filter that is composed of helical through holes generating centrifugal separating forces. In one example, the inertial filter may be a planar porous material with an array of helical channels, each helical channel of the array of helical channels extending from a top surface of the porous material to a bottom surface of the porous material.
FILED Friday, November 19, 2021
APPL NO 17/455736
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Separation
B01D 45/16 (20130101) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11779983 Winn et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Ross Winn (Houston, Texas);  Anthony Hood (Houston, Texas);  Heather Bergman (Houston, Texas);  Curtis Newman (Houston, Texas);  Eric Breaux (Houston, Texas)
ABSTRACT A tube straightening tool includes a tool housing having an exterior defining a tube entrance opening that opens into a first end of an internal cavity, and has an interior end wall at a second end of the internal cavity. The tool housing has an interior side wall extending from the tube entrance opening toward the interior end wall. A press block is in the internal cavity and a knob is external to the tool housing. A threaded shaft extends from the knob through the shaft opening into the internal cavity. The press block is coupled to the threaded shaft. Turning the knob moves the press block toward the interior side wall, and an exterior of a tube resting in the internal cavity is confronted by the press block and moved against the interior side wall. A method of straightening a tube using the tool is disclosed.
FILED Tuesday, July 20, 2021
APPL NO 17/381184
ART UNIT 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal
B21D 3/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780580 Izraelevitz et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Jacob S. Izraelevitz (Pasadena, California);  Brett A. Kennedy (Altadena, California);  Amanda R. Bouman (Pasadena, California);  Daniel Pastor Moreno (Pasadena, California);  Matthew James Lindsay Anderson (Pasadena, California);  Paul M. Nadan (San Carlos, California);  Joel W. Burdick (Pasadena, California)
ABSTRACT A ballistically launched foldable multirotor vehicle has a central body frame. A battery is located in an upper vertical location of the vehicle and positions a center of mass of the vehicle to provide aerodynamic stability during a launch. Fins are attached to the central body frame such that aerodynamic forces on the fins shift an aerodynamic center (AC) of the vehicle downward below the center of mass of the vehicle. Three or more foldable arms are attached to the central body frame via a hinge and exist in two states—a closed state where the foldable arms are parallel to a central body axis, and an open state (after launch) where the foldable arms extend radially outward perpendicular to the central body axis. Rotors mounted to each foldable arm are controlled by a motor to enable flight.
FILED Friday, October 09, 2020
APPL NO 17/067397
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 1/30 (20130101)
B64C 39/024 (20130101) Original (OR) Class

Unmanned aerial vehicles [UAV]; equipment therefor
B64U 10/13 (20230101)
B64U 30/12 (20230101)
B64U 30/20 (20230101)
B64U 50/19 (20230101)
B64U 70/00 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780612 Kopardekar et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Parimal Hemchandra Kopardekar (Cupertino, California);  Sreeja Nag (Redwood City, California);  David Daisuke Murakami (Sunnyvale, California)
ABSTRACT A Space Traffic Management (STM) system comprising a Space Traffic Management System Service Supplier (S3) interface for sending a space conjunction request to a Conjunction Assessment Supplier (CAS) interface, and a Space Situational Awareness Supplier (SSA) interface for receiving and fulfilling space object data requests. The system further comprising the Conjunction Assessment Supplier (CAS) interface for receiving the space conjunction request from the S3 interface, requesting and receiving the space object data from the SSA interface, and generating and sending a conjunction data message to the S3 interface. The system enables coordination of an automated service for spacecraft owner operators to anticipate and avoid a space traffic conjunction using the conjunction data message.
FILED Wednesday, September 23, 2020
APPL NO 17/030273
ART UNIT 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/14 (20130101)
B64G 1/24 (20130101) Original (OR) Class
B64G 1/46 (20130101)

Wireless Communication Networks
H04W 4/46 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781206 Manuel et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
John F. Kennedy Space Center (KSC)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  United States Of America As Represented By The Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  United States Of America As Represented By The Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Michele Viola Manuel (Gainesville, Florida);  Charles Robert Fisher (Fairfax, Virginia);  Maria Clara Wright (Orlando, Florida)
ABSTRACT Disclosed herein is a composite comprising a metal alloy matrix; where the metal alloy matrix comprises aluminum in an amount greater than 50 atomic percent; a first metal and a second metal; where the first metal is different from the second metal; and where the metal alloy matrix comprises a low temperature melting phase and a high temperature melting phase; where the low temperature melting phase melts at a temperature that is lower than the high temperature melting phase; and a contracting constituent; where the contracting constituent exerts a compressive force on the metal alloy matrix at a temperature between a melting point of the low temperature melting phase and a melting point of the high temperature melting phase or below the melting points of the high and low temperature melting phases.
FILED Thursday, April 28, 2022
APPL NO 17/661054
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Casting of Metals; Casting of Other Substances by the Same Processes or Devices
B22D 19/00 (20130101)
B22D 21/007 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/00 (20130101)
B22F 2301/15 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 15/20 (20130101)
B32B 2307/54 (20130101)

Alloys
C22C 1/0416 (20130101)
C22C 1/1036 (20130101)
C22C 1/1084 (20130101)
C22C 21/02 (20130101)
C22C 21/14 (20130101)
C22C 49/06 (20130101)
C22C 49/14 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/006 (20130101) Original (OR) Class
C22F 1/043 (20130101)
C22F 1/057 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781815 Alexander et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) ThermAvant Technologies, LLC (Columbia, Missouri)
ASSIGNEE(S) ThermAvant Technologies, LLC (Columbia, Missouri)
INVENTOR(S) Benjamin Alexander (Columbia, Missouri);  Daniel Pounds (Columbia, Missouri);  Joshua Schorp (St. Charles, Missouri);  Bruce Drolen (Altadena, California);  Corey Wilson (San Francisco, California);  Joseph Boswell (San Francisco, California)
ABSTRACT A heat rejection panel that comprises a chassis having a first side, an opposing second side, and an aperture extending therethrough. The panel additionally comprises at least one oscillating heat pipe (OHP) plate disposed over a portion of the first side and/or the second side of the chassis. Each OHP plate includes a first face, an opposing second face, and a plurality of internal OHP channels. A portion of the first face and/or second face of each OHP plate is accessible for thermal interfacing with a heat source. A portion of the second face of each OHP plate is accessible for thermal interfacing with a heat sink. Each OHP plate will remove heat from the heat source, spread the removed heat throughout each OHP plate to provide an isothermal OHP plate, and reject the heat to the heat sink.
FILED Tuesday, September 08, 2020
APPL NO 17/014681
ART UNIT 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 15/04 (20130101) Original (OR) Class
F28D 15/0208 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11782174 First et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Phillip Neal First (Atlanta, Georgia);  Zhigang Jiang (Atlanta, Georgia);  Thomas Michael Orlando (Atlanta, Georgia);  Elliot Christian Frey (Atlanta, Georgia)
ABSTRACT A radiation detector (100) includes an insulating substrate (110), which includes a material that undergoes a change in an electrical property when subjected to ionizing radiation. A conductive film (112) is disposed in relation to a surface of the substrate. The conductive film (112) has a resistance that is a function of a state of the electrical property. A resistance measuring device measures resistance across the conductive film (112). The resistance measured by the resistance measuring device indicates an amount of ionizing radiation to which the substrate (110) has been subjected. In a method of determining exposure to a type of radiation, a boron nitride substrate is exposed to a radiation environment. A resistance is measured across a conductive film disposed in relation to the boron nitride substrate. Radiation exposure is calculated as a function of the resistance.
FILED Friday, July 10, 2020
APPL NO 17/625206
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/26 (20130101) Original (OR) Class
G01T 3/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11783228 Harrivel et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Angela R. Harrivel (Poquoson, Virginia);  Chad L. Stephens (Poquoson, Virginia);  Kellie D. Kennedy (Poquoson, Virginia);  Alan T. Pope (Poquoson, Virginia)
ABSTRACT Aspects of the present disclosure are directed to devices, systems, and methods for optimized integration of a human operator with a machine for safe and efficient operation. Accordingly, aspects of the present disclosure are directed to systems, methods, and devices which evaluate and determine a cognitive state of an operator, and allocate tasks to either the machine and/or operator based on the cognitive state of the operator, among other factors.
FILED Tuesday, May 04, 2021
APPL NO 17/307639
ART UNIT 2800 — Semiconductors, Electrical and Optical Systems and Components
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/18 (20130101)
A61B 5/021 (20130101)
A61B 5/0022 (20130101)
A61B 5/0075 (20130101)
A61B 5/318 (20210101)
A61B 5/369 (20210101)
A61B 5/389 (20210101)
A61B 5/0816 (20130101)
A61B 5/7264 (20130101)

Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for
A63F 13/21 (20140901)
A63F 13/42 (20140902)
A63F 13/67 (20140902)
A63F 13/212 (20140902)
A63F 13/428 (20140902)

Electric Digital Data Processing
G06F 3/011 (20130101)
G06F 3/015 (20130101)
G06F 2203/011 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101) Original (OR) Class

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11784413 Bray
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Matthew G. Bray (Ellicott City, Maryland)
ABSTRACT An antenna includes a waveguide defined by a gap between a backplane with radial support ribs and a facesheet, a teardrop-shaped feed pin at a center of the backplane, and a foam spacer between the backplane and facesheet. An outward facing side of the facesheet includes thermal paint. The facesheet includes pairs of through-hole slots for releasing portions of a wave of radiation in the waveguide to generate a transmit-beam or to receive the receive-beam to generate the wave of radiation. The pairs may be disposed as a spiral array about a center of the facesheet. Each of the pairs may include first and second slots. A length of the second slot is oriented approximately perpendicular to a length of the first slot. Dispositions of the slots are set by a computer process. The dispositions optimize a trade-off between transmit and receive gains.
FILED Monday, March 28, 2022
APPL NO 17/705554
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/40 (20130101)
H01Q 9/0421 (20130101) Original (OR) Class
H01Q 19/13 (20130101)
H01Q 19/15 (20130101)
H01Q 21/0012 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11779040 Lucey et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) John A. Lucey (Madison, Wisconsin);  Dani Zhu (Madison, Wisconsin);  Srinivasan Damodaran (Middleton, Wisconsin)
ABSTRACT The present invention provides novel compositions and methods for producing protein-polysaccharide conjugates in aqueous solutions. Also provided are methods for limiting the Maillard reaction to the very initial stage, the formation of the Schiff base. Provided are methods to obtain a simple product of Schiff base with white color, and compositions obtained using the methods of the present invention.
FILED Tuesday, July 28, 2020
APPL NO 16/941100
ART UNIT 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof
A23C 21/08 (20130101)

Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs
A23J 3/08 (20130101)

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 2/66 (20130101)
A23L 5/00 (20160801)
A23L 27/60 (20160801)
A23L 27/84 (20160801)
A23L 29/10 (20160801)
A23L 29/30 (20160801) Original (OR) Class
A23L 33/125 (20160801)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)
A23V 2002/00 (20130101)
A23V 2002/00 (20130101)
A23V 2002/00 (20130101)
A23V 2002/00 (20130101)
A23V 2200/16 (20130101)
A23V 2200/222 (20130101)
A23V 2200/222 (20130101)
A23V 2200/304 (20130101)
A23V 2200/304 (20130101)
A23V 2250/5042 (20130101)
A23V 2250/5042 (20130101)
A23V 2250/5042 (20130101)
A23V 2250/54246 (20130101)
A23V 2250/54252 (20130101)
A23V 2250/54252 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/20 (20130101)

Peptides
C07K 14/4717 (20130101)

Polysaccharides; Derivatives Thereof
C08B 37/0021 (20130101)

Derivatives of Natural Macromolecular Compounds
C08H 1/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780950 Stewart et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Novol, Inc. (San Leandro, California)
ASSIGNEE(S) Monica Bhatia (San Ramon, California)
INVENTOR(S) Ray F. Stewart (San Leandro, California);  Monica Bhatia (San Leandro, California);  Jagdish Jethmalani (San Leandro, California);  Sanjiban Chakraborty (San Leandro, California)
ABSTRACT The present invention is based, in part, on the discovery that the polymeric materials described herein produce polyurethane copolymers with advantageous optical properties. In particular embodiments, polyurethane copolymers comprise repeating units of isosorbide and a difunctional linker where the difunctional linkers can be diisocyanate, diisothiocyanate, dicarboxylic acid, and other monomers. Some of the advantageous optical properties of these polymeric materials include a refractive index of about 1.5 and an Abbe value of at least about 50. Also described are methods for producing these polyurethane copolymers.
FILED Friday, May 01, 2020
APPL NO 16/864681
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 493/04 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/73 (20130101)
C08G 18/3218 (20130101) Original (OR) Class
C08G 18/7664 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/041 (20130101)
G02B 1/045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11781032 Catchmark et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Panama)
INVENTOR(S) Jeffrey M. Catchmark (State College, Pennsylvania);  Adam Ross Plucinski (State College, Pennsylvania)
ABSTRACT This document provides polymer compositions (e.g., biopolymer compositions) and coatings. For example, methods and materials related to polymer compositions (e.g., biopolymer compositions) and coatings as well as methods and materials for making and using such compositions (e.g., biopolymer compositions) and coatings are provided.
FILED Thursday, November 05, 2020
APPL NO 17/090593
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/26 (20130101)
C08K 3/26 (20130101)
C08K 3/346 (20130101)
C08K 3/346 (20130101)

Compositions of Macromolecular Compounds
C08L 1/02 (20130101)
C08L 1/02 (20130101)
C08L 1/02 (20130101)
C08L 1/02 (20130101)
C08L 1/02 (20130101)
C08L 1/286 (20130101)
C08L 1/286 (20130101)
C08L 1/286 (20130101)
C08L 5/08 (20130101)
C08L 5/08 (20130101)
C08L 5/08 (20130101)
C08L 89/005 (20130101)
C08L 89/005 (20130101)
C08L 89/005 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 101/286 (20130101) Original (OR) Class
C09D 101/286 (20130101)
C09D 101/286 (20130101)
C09D 101/286 (20130101)
C09D 105/00 (20130101)
C09D 105/08 (20130101)
C09D 105/08 (20130101)
C09D 105/08 (20130101)
C09D 105/08 (20130101)

Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for
D21H 11/18 (20130101)
D21H 17/22 (20130101)
D21H 17/25 (20130101)
D21H 17/68 (20130101)
D21H 19/40 (20130101)
D21H 19/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11779778 Friedman
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Integrated Sensors, LLC (Ottawa Hills, Ohio)
ASSIGNEE(S) Integrated Sensors, LLC (Palm Beach Gardens, Florida)
INVENTOR(S) Peter S. Friedman (Ottawa Hills, Ohio)
ABSTRACT Embodiments are directed generally to an ionizing-radiation beamline monitoring system that includes a vacuum chamber structure with vacuum compatible flanges through which an incident ionizing-radiation beam enters the monitoring system. Embodiments further include at least one scintillator within the vacuum chamber structure that can be at least partially translated in the ionizing-radiation beam while oriented at an angle greater than 10 degrees to a normal of the incident ionizing-radiation beam, a machine vision camera coupled to a light-tight structure at atmospheric/ambient pressure that is attached to the vacuum chamber structure by a flange attached to a vacuum-tight viewport window with the camera and lens optical axis oriented at an angle of less than 80 degrees with respect to a normal of the scintillator, and at least one ultraviolet (“UV”) illumination source facing the scintillator in the ionizing-radiation beam for monitoring a scintillator stability comprising scintillator radiation damage.
FILED Wednesday, October 20, 2021
APPL NO 17/451517
ART UNIT 2884 — Optics
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/00 (20130101)
A61N 5/1045 (20130101)
A61N 5/1048 (20130101)
A61N 5/1049 (20130101)
A61N 5/1064 (20130101)
A61N 5/1067 (20130101) Original (OR) Class
A61N 5/1077 (20130101)
A61N 2005/1059 (20130101)
A61N 2005/1087 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/29 (20130101)
G01T 1/40 (20130101)
G01T 1/1612 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11780950 Stewart et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Novol, Inc. (San Leandro, California)
ASSIGNEE(S) Monica Bhatia (San Ramon, California)
INVENTOR(S) Ray F. Stewart (San Leandro, California);  Monica Bhatia (San Leandro, California);  Jagdish Jethmalani (San Leandro, California);  Sanjiban Chakraborty (San Leandro, California)
ABSTRACT The present invention is based, in part, on the discovery that the polymeric materials described herein produce polyurethane copolymers with advantageous optical properties. In particular embodiments, polyurethane copolymers comprise repeating units of isosorbide and a difunctional linker where the difunctional linkers can be diisocyanate, diisothiocyanate, dicarboxylic acid, and other monomers. Some of the advantageous optical properties of these polymeric materials include a refractive index of about 1.5 and an Abbe value of at least about 50. Also described are methods for producing these polyurethane copolymers.
FILED Friday, May 01, 2020
APPL NO 16/864681
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Heterocyclic Compounds
C07D 493/04 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/73 (20130101)
C08G 18/3218 (20130101) Original (OR) Class
C08G 18/7664 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/041 (20130101)
G02B 1/045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11779551 Rein et al.
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S) Kathleen S. Rein (Miami, Florida);  Yuan Liu (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERISTY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Kathleen S. Rein (Miami, Florida);  Yuan Liu (Miami, Florida)
ABSTRACT The subject invention provides compounds as antitoxins for mitigating the toxic effects of algal toxins, e.g., brevetoxins. These compounds are mercaptan based compounds and derivatives that react rapidly with such toxins, e.g., brevetoxins and can be used to treat poisoning in a subject caused by such toxins. The subject invention also provides compositions comprising the mercaptan based compounds and derivatives for use to mitigate the toxic effects of brevetoxins. Further provided are methods of using the mercaptan based compounds and derivatives and compositions for treating and/or preventing brevetoxin poisoning in a subject such a human and marine animal.
FILED Tuesday, October 25, 2022
APPL NO 18/049468
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/095 (20130101) Original (OR) Class
A61K 31/145 (20130101)
A61K 31/375 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11779266 Woodward
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Steven H. Woodward (Palo Alto, California)
ABSTRACT A portable polysomnography apparatus comprises a unitary flexible structured pillow that is embedded with one or more sensors for data collection. The one or more sensors can comprise a tilt sensor that is configured to generate respiratory effort signals based on tilting of the head of the subject on the pillow. The one or more sensors can further be configured to generate ballistocardiogram signals from movement of the head of the subject caused by beating of the heart of the subject. The polysomnography apparatus can be advantageously sized and shaped to cause the sleeping subject to properly orient her head with respect to the sensors for optimal data collection while the subject is asleep.
FILED Friday, November 20, 2020
APPL NO 17/100163
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0002 (20130101)
A61B 5/002 (20130101)
A61B 5/11 (20130101)
A61B 5/70 (20130101)
A61B 5/369 (20210101)
A61B 5/389 (20210101)
A61B 5/398 (20210101)
A61B 5/4806 (20130101) Original (OR) Class
A61B 5/6887 (20130101)
A61B 5/6892 (20130101)
A61B 5/14542 (20130101)
A61B 2562/0219 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 11779542 Murphy et al.
FUNDED BY
Environmental Protection Agency (EPA)
National Science Foundation (NSF)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) William L. Murphy (Waunakee, Wisconsin);  Andrew Salim Khalil (Madison, Wisconsin);  Xiaohua Yu (Mansfield Center, Connecticut)
ABSTRACT Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonucleic acid, and an interferon binding protein. Ribonucleic acids and interferon binding proteins can be adsorbed to the mineral layer, can be incorporated into the mineral Layer, and combinations thereof. Also disclosed are methods for co-delivery of ribonucleic acids and interferon binding proteins and methods for treating inflammatory diseases using mineral coated microparticles having a mineral layer to provide co-delivery of ribonucleic acids and interferon binding proteins.
FILED Monday, July 19, 2021
APPL NO 17/379351
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/501 (20130101) Original (OR) Class
A61K 38/162 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/88 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11784920 Roweth et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Spring, Texas)
INVENTOR(S) Duncan Roweth (Bristol, United Kingdom);  Edwin L. Froese (Burnaby, Canada);  Joseph G. Kopnick (Chippewa Falls, Wisconsin);  Andrew S. Kopser (Seattle, Washington);  Robert Alverson (Seattle, Washington)
ABSTRACT Systems and methods are provided for passing data amongst a plurality of switches having a plurality of links attached between the plurality of switches. At a switch, a plurality of load signals are received from a plurality of neighboring switches. Each of the plurality of load signals are made up of a set of values indicative of a load at each of the plurality of neighboring switches providing the load signal. Each value within the set of values provides an indication for each link of the plurality of links attached thereto as to whether the link is busy or quiet. Based upon the plurality of load signals, an output link for routing a received packet is selected, and the received packet is routed via the selected output link.
FILED Monday, March 23, 2020
APPL NO 17/594736
ART UNIT 2419 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Electric Digital Data Processing
G06F 9/505 (20130101)
G06F 9/546 (20130101)
G06F 12/0862 (20130101)
G06F 12/1036 (20130101)
G06F 12/1063 (20130101)
G06F 13/14 (20130101)
G06F 13/16 (20130101)
G06F 13/385 (20130101)
G06F 13/1642 (20130101)
G06F 13/1673 (20130101)
G06F 13/1689 (20130101)
G06F 13/4022 (20130101)
G06F 13/4068 (20130101)
G06F 13/4221 (20130101)
G06F 15/17331 (20130101)
G06F 2212/50 (20130101)
G06F 2213/0026 (20130101)
G06F 2213/3808 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0083 (20130101)
H04L 43/10 (20130101)
H04L 43/0876 (20130101)
H04L 45/16 (20130101)
H04L 45/20 (20130101)
H04L 45/021 (20130101)
H04L 45/22 (20130101)
H04L 45/24 (20130101)
H04L 45/028 (20130101)
H04L 45/28 (20130101) Original (OR) Class
H04L 45/38 (20130101)
H04L 45/42 (20130101)
H04L 45/46 (20130101)
H04L 45/70 (20130101)
H04L 45/122 (20130101)
H04L 45/123 (20130101)
H04L 45/125 (20130101)
H04L 45/566 (20130101)
H04L 45/745 (20130101)
H04L 45/7453 (20130101)
H04L 47/11 (20130101)
H04L 47/12 (20130101)
H04L 47/18 (20130101)
H04L 47/20 (20130101)
H04L 47/22 (20130101)
H04L 47/24 (20130101)
H04L 47/30 (20130101)
H04L 47/32 (20130101)
H04L 47/34 (20130101)
H04L 47/39 (20130101)
H04L 47/52 (20130101)
H04L 47/76 (20130101)
H04L 47/80 (20130101)
H04L 47/122 (20130101)
H04L 47/323 (20130101)
H04L 47/621 (20130101)
H04L 47/626 (20130101)
H04L 47/629 (20130101)
H04L 47/762 (20130101)
H04L 47/781 (20130101)
H04L 47/2441 (20130101)
H04L 47/2466 (20130101)
H04L 47/2483 (20130101)
H04L 47/6235 (20130101)
H04L 47/6275 (20130101)
H04L 49/15 (20130101)
H04L 49/30 (20130101)
H04L 49/90 (20130101)
H04L 49/101 (20130101)
H04L 49/3009 (20130101)
H04L 49/3018 (20130101)
H04L 49/3027 (20130101)
H04L 49/9005 (20130101)
H04L 49/9021 (20130101)
H04L 49/9036 (20130101)
H04L 49/9047 (20130101)
H04L 67/1097 (20130101)
H04L 69/22 (20130101)
H04L 69/28 (20130101)
H04L 69/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Nuclear Regulatory Commission (NRC) 

US 11783953 Sorbom et al.
FUNDED BY
Nuclear Regulatory Commission (NRC)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Brandon Nils Sorbom (Cambridge, Massachusetts);  Zachary Hartwig (Jamaica Plain, Massachusetts);  Dennis G. Whyte (Brookline, Massachusetts)
ABSTRACT Disclosed are a superconductor having improved critical current density when exposed to high-energy neutron radiation and high magnetic fields, such as found in a compact nuclear fusion reactor, and a method of making the same. The method includes, prior to deployment in the exposure environment, irradiating a polycrystalline (e.g. cuprate) superconductor with ionic matter or neutrons at a cryogenic temperature to create “weak” magnetic flux pinning sites, such as point defects or small defect clusters. Irradiation temperature is chosen, for example as a function of the superconducting material, so that irradiation creates the beneficial flux pinning sites while avoiding detrimental widening of the boundaries of the crystalline grains caused by diffusion of the displaced atoms. Such a superconductor in a coated-conductor tape is expected to be beneficial when used, for example, as a toroidal field coil in a fusion reactor when cooled well below its critical temperature.
FILED Tuesday, June 18, 2019
APPL NO 16/444467
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 3/006 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/52 (20130101)
C01P 2006/40 (20130101)

Fusion Reactors
G21B 1/057 (20130101) Original (OR) Class

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 12/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 11779592 Wang et al.
FUNDED BY
U.S. State Government
State of Texas
Cancer Prevention and Research Institute of Texas (TX-CPRIT)
APPLICANT(S) University of North Texas Health Science Center (Fort Worth, Texas)
ASSIGNEE(S) UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER (Fort Worth, Texas)
INVENTOR(S) Yu-Chieh Wang (Fort Worth, Texas);  Victor J. T. Lin (Fort Worth, Texas);  Ashwini Zolekar (Fort Worth, Texas);  Kyle A. Emmitte (Aledo, Texas);  Nigam M. Mishra (Fort Worth, Texas);  Jin Liu (Dallas, Texas)
ABSTRACT In one aspect, the present disclosure provides GlcNAc-Asn analogs of the formula (I): wherein the variables are as defined herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of using the compounds disclosed herein. Additionally, the present disclosure also provides methods of treating cancer comprising inhibiting NGLY1.
FILED Tuesday, August 14, 2018
APPL NO 16/639027
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 309/14 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1137 (20130101)

Enzymes
C12Y 305/01052 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11783139 Ashaari et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Shahpour Ashaari (Bethesda, Maryland);  David C. Lin (Falls Church, Virginia);  Seth S. Vasa (Olney, Maryland);  Scott R. Bombaugh (Burke, Virginia);  Mario Andre Salisbury (Miami, Florida);  Thomas Jay Graham (Chantilly, Virginia);  Erich Joseph Petre (Gainesville, Virginia)
ABSTRACT Systems and methods of identifying wearable tags or other items within a facility. The location of the identifiable item can be calculated by the system and used to improve the efficiency of the facility or to dispatch emergency help or maintenance to the location of the badge.
FILED Friday, April 22, 2022
APPL NO 17/660377
ART UNIT 2876 — Optics
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/4183 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10099 (20130101) Original (OR) Class
G06K 7/10475 (20130101)
G06K 19/07758 (20130101)

Wireless Communication Networks
H04W 4/021 (20130101)
H04W 4/33 (20180201)
H04W 4/35 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 

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     National Institutes of Health (NIH)
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     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20231010.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital