FedInvent™ Patents

Patent Details for Tuesday, October 24, 2023 

This page was updated on Monday, November 20, 2023 at 03:52 AM GMT

Department of Health and Human Services (HHS) 

US 11793178 Bial et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) Yecuris Corporation (Tigard, Oregon)
ASSIGNEE(S) Yecuris Corporation (Tigard, Oregon)
INVENTOR(S) John R. Bial (Portland, Oregon);  Elizabeth M. Wilson (Tualatin, Oregon);  Aron M. Geurts (Milwaukee, Wisconsin)
ABSTRACT Described herein are rats with a hepatic deficiency comprising decreased function, activity, or expression of an enzyme in the tyrosine catabolic pathway (such as fumarylacetoacetate hydrolase), and methods of using the same for in vivo engraftment and expansion of heterologous hepatocytes, such as human hepatocytes, analysis of human liver disease, and analysis of xenobiotics. Also disclosed is the use of immunodeficient rats for the engraftment and expansion of heterologous hepatocytes.
FILED Friday, August 30, 2019
APPL NO 16/557155
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0276 (20130101) Original (OR) Class
A01K 67/0278 (20130101)
A01K 2207/12 (20130101)
A01K 2207/15 (20130101)
A01K 2217/00 (20130101)
A01K 2217/075 (20130101)
A01K 2227/105 (20130101)
A01K 2267/03 (20130101)
A01K 2267/0387 (20130101)

Peptides
C07K 14/7155 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/14 (20130101)
C12N 9/6462 (20130101)
C12N 2750/14143 (20130101)

Enzymes
C12Y 304/21073 (20130101)
C12Y 307/01002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793450 Mannoh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) Emmanuel A. Mannoh (Nashville, Tennessee);  Anita Mahadevan-Jansen (Nashville, Tennessee)
ABSTRACT One aspect of the invention relates to a method for intraoperative detection of parathyroid gland viability in a surgery, comprising obtaining speckle contrast images of a parathyroid gland of a patent; and displaying the speckle contrast images of the parathyroid gland in real-time.
FILED Wednesday, December 14, 2022
APPL NO 18/065707
ART UNIT 2877 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0071 (20130101)
A61B 5/0075 (20130101)
A61B 5/0086 (20130101)
A61B 5/415 (20130101) Original (OR) Class
A61B 5/418 (20130101)
A61B 5/742 (20130101)
A61B 5/4227 (20130101)
A61B 34/20 (20160201)
A61B 2034/2055 (20160201)
A61B 2505/05 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/65 (20130101)
G01N 21/6456 (20130101)
G01N 2021/6439 (20130101)
G01N 2201/0221 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793526 Alambeigi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Farshid Alambeigi (Baltimore, Maryland);  Mehran Armand (Fulton, Maryland)
ABSTRACT An embodiment in accordance with the present invention provides a continuum dexterous manipulator (CDM) with a specially designed flexible tool, to be used as a handheld or robotic steerable device for treatment of hard-tissue-related diseases. The CDM of the present invention works well in treatment of soft and sticky material (similar to a lesion) as well as milling the hard tissues (e.g. sclerotic liner of osteolytic lesions) and bone tumors. The present invention is also directed to flexible drilling tools as well as characterization and evaluation of integrating these tools with the CDM in curved-drilling of hard bone towards treatment of hard tissue related diseases (e.g. osteonecrosis or pelvic fracture). The present invention can also include use of various types of drill geometries, aspiration and irrigation, and endoscope view in curved-drilling and trajectory planning.
FILED Wednesday, January 03, 2018
APPL NO 16/490751
ART UNIT 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/00234 (20130101)
A61B 17/1617 (20130101)
A61B 17/1626 (20130101)
A61B 17/1631 (20130101)
A61B 17/1642 (20130101) Original (OR) Class
A61B 2017/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793573 Trayanova et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S) Natalia A. Trayanova (Baltimore, Maryland);  Kathleen Mcdowell (Baltimore, Maryland)
ABSTRACT Methods, system, and media for identifying one or more ablation locations in an atrial tissue region in an atrial fibrillation (AF) patient with atrial fibrosis are disclosed. Three-dimensional imaging data representing the atria of the patient may be received. A patient-specific model of the atria may be generated from the three-dimensional imaging data. Simulation of the AF on the patient-specific model may be conducted to identify AF-perpetrating regions. One or more ablation locations in the atria may be identified from the AF-perpetrating regions.
FILED Wednesday, October 21, 2020
APPL NO 17/076091
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/10 (20160201) Original (OR) Class
A61B 2018/00351 (20130101)
A61B 2034/101 (20160201)
A61B 2034/104 (20160201)
A61B 2034/105 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793765 Rohan
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Lisa Cencia Rohan (Pittsburgh, Pennsylvania)
ABSTRACT Provided herein are stable, dissolvable films containing active ingredients, such as antimicrobial composition, antiviral compositions, or anti-retroviral compositions for intravaginal or intrarectal placement to provide prophylaxis against viral infections.
FILED Tuesday, March 27, 2018
APPL NO 16/494804
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0031 (20130101)
A61K 9/0034 (20130101)
A61K 9/7007 (20130101) Original (OR) Class
A61K 31/505 (20130101)
A61K 31/675 (20130101)
A61K 47/10 (20130101)
A61K 47/38 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793781 Chandraratna et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Complementary and Integrative Health (NCCIH)
National Cancer Institute (NCI)
APPLICANT(S) Io Therapeutics, Inc. (Spring, Texas);  Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) Io Therapeutics, Inc. (Spring, Texas);  Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Roshantha A. Chandraratna (San Juan Capistrano, California);  Ethan Dmitrovsky (Hanover, New Hampshire);  Elizabeth Nowak (West Lebanon, New Hampshire);  Randolph Noelle (Plainfield, New Hampshire)
ABSTRACT The present specification provides RXR agonist compounds, compositions comprising such RXR agonists, and methods using such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection as well as use of such RXR agonists to manufacture a medicament and use of such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection.
FILED Thursday, January 27, 2022
APPL NO 17/586657
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0073 (20130101)
A61K 31/47 (20130101)
A61K 31/192 (20130101) Original (OR) Class
A61K 31/201 (20130101)
A61K 31/216 (20130101)
A61K 31/343 (20130101)
A61K 31/353 (20130101)
A61K 31/4704 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793787 Anderson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Ana Carrizosa Anderson (Boston, Massachusetts);  Asaf Madi (Boston, Massachusetts);  Nandini Acharya (Boston, Massachusetts);  Vijay K. Kuchroo (Boston, Massachusetts);  Aviv Regev (Cambridge, Massachusetts)
ABSTRACT The subject matter disclosed herein is generally directed to modulating anti-tumor T cell immunity by modulating steroidogenesis. Steroidogenesis may be modulated with inhibitors of enzymes that synthesize glucocorticoids in a tumor. The inhibitor may target Cyp11a1. The inhibitor may be metyrapone. The invention further relates to modulating immune states, such as CD8 T cell immune states, in vivo, ex vivo and in vitro. The invention further relates to diagnostic and screening methods.
FILED Wednesday, October 07, 2020
APPL NO 17/065328
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/4015 (20130101) Original (OR) Class

Peptides
C07K 16/2818 (20130101)
C07K 16/2827 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/10 (20130101)
C12N 15/113 (20130101)
C12N 2310/20 (20170501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793794 Abdallah et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut);  The United States of America as represented by the Department of Veteran Affairs (Washington, District of Columbia)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Chadi Abdallah (New Haven, Connecticut);  John Krystal (New Haven, Connecticut);  Ronald Duman (New Haven, Connecticut);  Gerard Sanacora (New Haven, Connecticut)
ABSTRACT The present invention provides compositions and methods for treating diseases or disorders using a therapeutically effective amount of a rapid-acting antidepressant (RAAD) and a therapeutically effective amount of a mTOR inhibitor and/or immunosuppressant. In certain embodiments, the RAAD and the mTOR inhibitor and/or immunosuppressant are part of a single pharmaceutical composition.
FILED Tuesday, October 25, 2022
APPL NO 18/049589
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/08 (20130101)
A61K 9/0053 (20130101)
A61K 31/135 (20130101)
A61K 31/436 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/24 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793816 Cheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Shi-Yuan Cheng (Glenview, Illinois);  Bo Hu (Glenview, Illinois);  Tianzhi Huang (Chicago, Illinois)
ABSTRACT Disclosed are methods and compositions for treating cell proliferative diseases and disorders such as cancers. Particularly disclosed are methods and composition for treating cancers such as glioblastoma by administering a therapeutic agent that inhibits the biological activity of the autophagy related 4B cysteine peptidase (ATG4B) protein in conjunction with additional therapeutic agents or treatments.
FILED Thursday, September 10, 2020
APPL NO 17/017351
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 31/53 (20130101)
A61K 31/427 (20130101)
A61K 31/436 (20130101)
A61K 31/437 (20130101)
A61K 31/444 (20130101)
A61K 31/495 (20130101)
A61K 31/519 (20130101)
A61K 31/5377 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793824 Imai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Shin-ichiro Imai (St. Louis, Missouri);  Rajendra Apte (Clayton, Missouri)
ABSTRACT Disclosed are methods and compositions related to methods of treating, ameliorating, mitigating, slowing, arresting, preventing or reversing various diseases and conditions, including age-related obesity, age-related increases in blood lipid levels, age-related decreases in insulin sensitivity, age-related decreases in memory function, and age-related changes in eye function such as macular degeneration. The methods comprise administering nicotinamide mononucleotide (NMN) to a subject. In some embodiments, the administration can be oral administration. Also disclosed are pharmaceutical compositions comprising NMN.
FILED Friday, January 15, 2021
APPL NO 17/150584
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/0048 (20130101)
A61K 9/0053 (20130101)
A61K 31/455 (20130101)
A61K 31/706 (20130101) Original (OR) Class
A61K 31/7064 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793829 Palli et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Department of Agriculture (USDA)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Subba Reddy Palli (Lexington, Kentucky);  Ramesh Dhandapani (Lexington, Kentucky)
ABSTRACT The present invention relates to a polyplex composition for modulating expression of a gene-of-interest in an insect comprising: a crosslinker, a cation, and a molecule for initiating RNA interference (RNAi). The present invention further relates to polyplex compositions for modulating genes of interest in Aedes aegypti. The present invention further relates to methods of modulating a gene-of-interest in an insect, comprising: administering to an insect a polyplex composition for modulating expression of a gene-of-interest in an insect comprising: a crosslinker, a cation, and a molecule for initiating RNA interference (RNAi).
FILED Friday, August 28, 2020
APPL NO 17/006588
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/08 (20130101)
A61K 9/0053 (20130101)
A61K 31/713 (20130101) Original (OR) Class
A61K 47/32 (20130101)
A61K 47/6937 (20170801)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793853 Palczewski et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Krzysztof Palczewski (Cleveland, Ohio);  Zheng-Rong Lu (Cleveland, Ohio)
ABSTRACT A pharmaceutical composition includes a retinylamine derivative having the following formula: where R1 is an amino acid residue, a dipeptide or a tripeptide that is linked to the retinylamine by an amide bond.
FILED Tuesday, November 12, 2019
APPL NO 16/681485
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 31/16 (20130101)
A61K 31/40 (20130101)
A61K 31/165 (20130101)
A61K 38/05 (20130101) Original (OR) Class
A61K 47/60 (20170801)
A61K 47/65 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793854 Wagner, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) OP-T LLC (Denver, Colorado)
ASSIGNEE(S) OP-T LLC (Aurora, Colorado)
INVENTOR(S) David Hal Wagner, Jr. (Denver, Colorado);  Martin Glenn Yussman (Denver, Colorado);  Charles W. Henry (Denver, Colorado);  Gisela M. Vaitaitis (Centennial, Colorado)
ABSTRACT Methods and materials for treating and preventing autoimmune diseases, in particular, multiple sclerosis (MS) including small peptides are capable of interacting with CD40, thereby altering and/or modulating the ability of CD40 to interact with CD154, which apparently affects inflammation; and/or the use of such peptides in reducing the inflammatory response, and in particular, the autoimmune inflammatory response; and/or the use of such short peptides to prevent or reverse autoimmune disease, and particularly, multiple sclerosis, in individuals; and/or methods and materials for detecting T-cells that express CD40 (Th40 cells). Also provided are kits for reducing inflammation, treating autoimmune diseases, or detecting Th40 cells. Additionally, methods and apparatuses to administer the peptide are provided.
FILED Monday, March 23, 2020
APPL NO 16/827523
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/07 (20130101)
A61K 38/08 (20130101) Original (OR) Class
A61K 38/10 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793860 Rome et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Leonard H. Rome (Tarzana, California);  Valerie Ann Kickhoefer (Sherman Oaks, California);  Steven M. Dubinett (Los Angeles, California);  Sherven Sharma (Oakland, California);  Upendra K. Kar (Oakland, California)
ABSTRACT The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
FILED Wednesday, August 12, 2020
APPL NO 16/991780
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)
A61K 38/00 (20130101)
A61K 38/45 (20130101)
A61K 38/195 (20130101) Original (OR) Class
A61K 47/6921 (20170801)
A61K 48/00 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 14/47 (20130101)
C07K 14/521 (20130101)
C07K 2319/00 (20130101)
C07K 2319/01 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 9/96 (20130101)
C12N 9/1077 (20130101)
C12N 15/86 (20130101)

Enzymes
C12Y 204/0203 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/535 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793871 Boyington et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Jeffrey C. Boyington (Clarksburg, Maryland);  Barney S. Graham (Smyrna, Georgia);  John R. Mascola (Rockville, Maryland);  Hadi M. Yassine (Doha, Qatar);  Kizzmekia S. Corbett (Wheaton, Maryland);  Syed M. Moin (Laurel, Maryland);  Lingshu Wang (North Potomac, Maryland);  Masaru Kanekiyo (Chevy Chase, Maryland)
ABSTRACT Vaccines that elicit broadly protective anti-influenza antibodies. The vaccines comprise nanoparticles that display HA trimers from Group 2 influenza virus on their surface. The nanoparticles are fusion proteins comprising a monomeric subunit (e.g., ferritin) joined to stabilized stem regions of Group 2 influenza virus HA proteins. The fusion proteins self-assemble to form the HA-displaying nanoparticles. Also provided are fusion proteins, and nucleic acid molecules encoding such proteins, and assays using nanoparticles of the invention to detect anti-influenza antibodies.
FILED Wednesday, May 11, 2022
APPL NO 17/742201
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/145 (20130101) Original (OR) Class
A61K 2039/55555 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/16 (20180101)

Peptides
C07K 14/005 (20130101)
C07K 14/195 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2760/16122 (20130101)
C12N 2760/16134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793872 Friedman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Harvey Friedman (Merion, Pennsylvania);  Drew Weissman (Wynnewood, Pennsylvania);  Sita Awasthi (Bala Cynwyd, Pennsylvania);  Gary Cohen (Havertown, Pennsylvania)
ABSTRACT Compositions for the prevention and treatment of genital herpes, comprising nucleoside modified mRNAs that encode herpes simplex virus (HSV) glycoproteins, including those involved in virus entry and immune evasion, and methods of use thereof.
FILED Thursday, June 17, 2021
APPL NO 17/349929
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0036 (20130101)
A61K 39/245 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/54 (20130101)
A61K 2039/57 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/22 (20180101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/11 (20130101)
C12N 2710/16622 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793873 Libraty
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Daniel H. Libraty (Newton, Massachusetts)
ABSTRACT The present invention relates to the construction of, and immunization with viral vaccines. In particular, bivalent vaccines that are capable of providing simultaneous virus infection protection for two or more different viruses. Furthermore, the bivalent vaccines contemplated herein are contemplated as being effective in a neonatal mammal. One such bivalent viral vaccine comprises two antigenic epitopes against the dengue viruses and at least one antigenic epitope against hepatitis B virus. Immunization cross-reactivity may also provide infection protection against other viruses as well.
FILED Tuesday, May 01, 2018
APPL NO 16/612152
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/292 (20130101)
A61K 39/295 (20130101) Original (OR) Class
A61K 47/65 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
A61P 31/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793884 Pei et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Dehua Pei (Columbus, Ohio);  Patrick G. Dougherty (Columbus, Ohio)
ABSTRACT Described herein, in various embodiments, are peptides comprising: (i) a cyclic cell-penetrating peptide sequence (cCPP) and (ii) a CAL-PDZ binding sequence, which is conjugated, directly or indirectly, to an N-terminus of an amino acid in the cCPP, to a C-terminus of an amino acid on the cCPP, or on a side chain of an amino acid in the cCPP. In other embodiments, the peptides further comprise a physiologically cleavable group, wherein after entering the cell, the physiologically cleavable group is reduced, thereby providing a linear peptide. Without being bound by theory, the inventors discovered that the amino acid sequence in the cCPP, which facilities cytosolic delivery of the CAL-PDZ binding sequence also, surprisingly and unexpectedly, synergistically improves binding of CAL-PDZ binding sequence to the CAL-PDZ binding domain. Additionally, the cCPP sequence may also improve selectivity of the CAL-PDZ binding sequence for the CAL-PDZ domain relative to other PDZ binding domains.
FILED Tuesday, January 29, 2019
APPL NO 16/965713
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 38/08 (20130101)
A61K 45/06 (20130101)
A61K 47/645 (20170801) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 11/00 (20180101)

Peptides
C07K 7/06 (20130101)
C07K 14/47 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793982 Lee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana);  Industry-University Cooperation Foundation Hanyang University (Seoul, South Korea)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana);  Industry-University Cooperation Foundation Hanyang University (Seoul, South Korea)
INVENTOR(S) Chi Hwan Lee (West Lafayette, Indiana);  Yoon Yeo (West Lafayette, Indiana);  Dong Rip Kim (Seoul, South Korea)
ABSTRACT Drug delivery devices that have a flexible film, an array of nanoscopic, porous needles attached to a surface of the flexible film, and a therapeutic drug cargo loaded onto the needles. The drug delivery device may be applied to living tissue such that the surface of the flexible film contacts the living tissue and some or all of the needles are inserted into the tissue. The flexible film may then be dissolved while leaving the needles inserted in the tissue. The needles degrade in the living tissue over time causing release of the therapeutic drug cargo loaded onto the needles.
FILED Thursday, June 10, 2021
APPL NO 17/344362
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0015 (20130101) Original (OR) Class
A61M 2037/0023 (20130101)
A61M 2037/0053 (20130101)
A61M 2205/0244 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793983 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Xucai Chen (Pittsburgh, Pennsylvania);  Qin Bin (Pittsburgh, Pennsylvania);  Villanueva Flordeliza (Pittsburgh, Pennsylvania)
ABSTRACT The systems and methods disclosed herein relate generally to microbubble-assisted delivery of a therapeutic agent, such as a chemotherapeutic agent, to cells or tissue of interest, either in vitro or in vivo, that can be activated by directed ultrasound irradiation. For example, hydrophobic sonosensitizers can be incorporated in microbubble complexes to provide improved sonodynamic therapies.
FILED Wednesday, September 05, 2018
APPL NO 16/644482
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0009 (20130101)
A61K 31/409 (20130101)
A61K 41/0047 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0092 (20130101) Original (OR) Class
A61M 2210/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794009 Tai
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Changfeng Tai (Wexford, Pennsylvania)
ABSTRACT Provided herein are devices, systems, and methods for treating urological and gastrointestinal disorders, including bedwetting, through stimulation of the dorsal or plantar surface of the foot, including the superficial peroneal nerve and branches thereof, such as the dorsal intermediate and medial cutaneous nerves, or the medial and/or and lateral plantar nerves. The device facilitates placement of electrodes on the foot. Also provided herein is a system including the device, a pulse generator, and a controller, and methods of manufacturing and using the same.
FILED Wednesday, May 12, 2021
APPL NO 17/318110
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/137 (20130101)
A61K 31/381 (20130101)
A61K 31/428 (20130101)
A61K 31/435 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/04 (20130101)
A61N 1/18 (20130101)
A61N 1/24 (20130101)
A61N 1/32 (20130101)
A61N 1/372 (20130101)
A61N 1/0456 (20130101)
A61N 1/0484 (20130101)
A61N 1/0492 (20130101)
A61N 1/3603 (20170801)
A61N 1/36007 (20130101) Original (OR) Class
A61N 1/36021 (20130101)
A61N 1/36034 (20170801)
A61N 1/37264 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794012 Napadow et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Institute of Mental Health (NIMH)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Vitaly Napadow (Boston, Massachusetts);  Jill M. Goldstein (Boston, Massachusetts);  Ronald G. Garcia (Boston, Massachusetts);  Benjamin Pless (Boston, Massachusetts)
ABSTRACT Systems and methods are provided for neurostimulation timed relative to respiratory activity. Neurostimulation may be delivered to the spinal cord, the vagus nerve, and/or branches of the vagus nerve to provide therapeutic outcomes by controlling or adjusting stimulation based on pulmonary activity. In particular, the systems and methods use a detecting device to detect respiratory activity over time. Specific points in the respiratory signal are identified where central autonomic nuclei may be more receptive to afferent input and a stimulator is instructed to provide neurostimulation to at least one auricular branch of a vagus nerve, or to a cervical branch of the vagus nerve, or to a spinal cord of the subject. In this regard, the neurostimulation is advantageously correlated to the detected respiratory activity providing improved therapeutic outcomes.
FILED Tuesday, July 10, 2018
APPL NO 16/629395
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0502 (20130101)
A61N 1/0551 (20130101)
A61N 1/36053 (20130101) Original (OR) Class
A61N 1/36096 (20130101)
A61N 1/36139 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794013 Kressel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Feinstein Institutes for Medical Research (Manhasset, New York)
ASSIGNEE(S) The Feinstein Institutes for Medical Research (Manhasset, New York)
INVENTOR(S) Adam M. Kressel (Plainview, New York);  Valentin A. Pavlov (Bayside, New York);  Sangeeta S. Chavan (Syosset, New York);  Kevin J. Tracey (Old Greenwich, Connecticut)
ABSTRACT Methods for electrical modulation of inflammation or serum TNF levels in a subject.
FILED Wednesday, February 24, 2021
APPL NO 17/184197
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0412 (20130101)
A61N 1/0504 (20130101)
A61N 1/0536 (20130101)
A61N 1/3615 (20130101)
A61N 1/36053 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794413 McAlpine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Michael C. McAlpine (Minneapolis, Minnesota);  Zhijie Zhu (Minneapolis, Minnesota)
ABSTRACT Systems and techniques are described for additive manufacturing, e.g., 3D printing, a component on an unconstrained freeform build surface. The systems and techniques may allow determining a 3D trajectory and/or deformation of a target deposition region on the build surface by determining a relative location of at least one registration feature on the build surface. Control circuitry may control, based on the 3D trajectory and/or deformation and based on a build model of the component, at least one dispenser to cause dispensing of at least one composition from the at least one dispenser in a predetermined pattern on or adjacent to the target deposition region. The predetermined pattern of the composition defines at least one portion of the component.
FILED Tuesday, July 02, 2019
APPL NO 16/460194
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/112 (20170801)
B29C 64/393 (20170801) Original (OR) Class

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2071/02 (20130101)
B29K 2105/0094 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)
B33Y 70/10 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795077 Ball
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) OXYTEC LLC (Newton, Massachusetts)
ASSIGNEE(S) OXYTEC LLC (Newton, Massachusetts)
INVENTOR(S) Raymond G. Ball (Newton, Massachusetts)
ABSTRACT Disclosed are methods, apparatuses and systems for the remediation of contaminated soils, groundwater, water, and/or waste using a combination of reagents. The disclosed methods may be used to treat various recalcitrant halogenated substances, such as perfluoroalkyls and polyfluoroalkyls. Particular combinations of reagents that may be used in the disclosed methods include but are not limited to: (1) persulfate, oxygen and ozone; (2) persulfate, salt, oxygen and ozone; (3) persulfate, phosphate, and/or oxygen; (4) persulfate, phosphate, oxygen and ozone; (5) persulfate, phosphate, salt and oxygen (6) persulfate, phosphate, salt, oxygen and ozone; (7) oxygen and salt; and (8) air and salt. The disclosed methods may enhance destruction of organic contaminants in the liquid phase and may also control the rate of aerosol or foam formation relative to the rate of chemical oxidation and/or reduction/transfer.
FILED Monday, March 28, 2022
APPL NO 17/706128
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Reclamation of Contaminated Soil
B09C 1/002 (20130101)
B09C 1/06 (20130101)
B09C 1/08 (20130101)
B09C 2101/00 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/32 (20130101)
C02F 1/70 (20130101)
C02F 1/78 (20130101)
C02F 1/722 (20130101) Original (OR) Class
C02F 1/725 (20130101)
C02F 1/727 (20130101)
C02F 2101/34 (20130101)
C02F 2101/36 (20130101)
C02F 2101/305 (20130101)
C02F 2101/306 (20130101)
C02F 2101/322 (20130101)
C02F 2101/327 (20130101)
C02F 2101/363 (20130101)
C02F 2103/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795159 Ghosh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Arun K. Ghosh (West Lafayette, Indiana);  Hiroaki Mitsuya (Kumamoto, Japan);  Andrew Mesecar (West Lafayette, Indiana);  Dana Shahabi (West Lafayette, Indiana)
ABSTRACT Bis-amide inhibitors of SARS-CoV-2 (COVID); pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.
FILED Monday, May 23, 2022
APPL NO 17/751659
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 401/12 (20130101) Original (OR) Class
C07D 401/14 (20130101)
C07D 413/12 (20130101)
C07D 413/14 (20130101)
C07D 417/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795162 Burris et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Saint Louis University (St. Louis, Missouri)
ASSIGNEE(S) Saint Louis University (St. Louis, Missouri)
INVENTOR(S) Thomas Burris (Columbia, Illinois);  John K. Walker (St. Louis, Missouri);  Carissa S. Hampton (Litchfield, Illinois);  Keith McCormick Haynes (St. Louis, Missouri);  Kristine Griffett (St. Louis, Missouri);  Cyrielle Billon (St. Louis, Missouri);  Sadichha Sitaula (St. Louis, Missouri)
ABSTRACT In one aspect, the present disclosure describes new estrogen receptor-related orphan receptor (EER) inverse agonist compounds. Also described are pharmaceutical formulations, methods of synthesis and uses thereof.
FILED Friday, August 17, 2018
APPL NO 16/639807
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 209/42 (20130101)
C07D 231/14 (20130101)
C07D 277/56 (20130101)
C07D 277/82 (20130101)
C07D 307/68 (20130101)
C07D 333/38 (20130101)
C07D 401/04 (20130101)
C07D 409/04 (20130101)
C07D 409/12 (20130101)
C07D 413/04 (20130101) Original (OR) Class
C07D 417/04 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795177 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Shyh Ming Yang (Doylestown, Pennsylvania);  David J. Maloney (Points of Rocks, Maryland);  Natalia Martinez (Rockville, Maryland);  Adam Yasgar (Washington, District of Columbia);  Anton Simeonov (Bethesda, Maryland)
ABSTRACT The disclosure provides compounds of Formula I, which may be useful as aldehyde dehydrogenase inhibitors and the pharmaceutically acceptable salts thereof. The variables, J, R4, G, Q, and ring A are defined herein. Aldehyde dehydrogenase inhibitors of Formula I are useful for treating a variety of conditions including cancer and inflammation. The disclosure includes methods for using compounds and salts of Formula I to treat colon cancer, pancreatic cancer, nasopharyngeal carcinoma, thyroid cancer, prostate cancer, ovarian cancer, head and neck squamous cell carcinoma, lung cancer, hepatocellular carcinoma, leukemia, brain tumors breast cancer, atherosclerosis, ischaemic heart disease, acne vulgaris, asthma, autoimmune diseases, autoinflammatory diseases, chronic prostatitis, glomerulonephritis, inflammatory bowel disease, pelvic inflammatory disease, reperfusion injury, rheumatoid arthritis, sarcoidosis, transplant rejection, vasculitis, and interstitial cystitis. The disclosure also includes pharmaceutical compositions containing a compound or salt of Formula I.
FILED Monday, February 28, 2022
APPL NO 17/682654
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 215/54 (20130101)
C07D 401/04 (20130101)
C07D 401/06 (20130101)
C07D 401/12 (20130101)
C07D 401/14 (20130101)
C07D 409/14 (20130101)
C07D 413/04 (20130101)
C07D 471/04 (20130101)
C07D 491/107 (20130101)
C07D 491/113 (20130101) Original (OR) Class
C07D 495/04 (20130101)
C07D 495/10 (20130101)
C07D 519/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795191 Ju et al.
FUNDED BY
Department of Commerce (DOC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Shiv Kumar (Belle Mead, New Jersey);  Chuanjuan Tao (New York, New York);  Minchen Chien (Tenafly, New Jersey);  James J. Russo (New York, New York);  John J. Kasianowicz (Darnestown, Maryland);  Joseph W. F. Robertson (Washington, District of Columbia)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York);  GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Shiv Kumar (Belle Mead, New Jersey);  Chuanjuan Tao (New York, New York);  Minchen Chien (Tenafly, New Jersey);  James J. Russo (New York, New York);  John J. Kasianowicz (Darnestown, Maryland);  Joseph W. F. Robertson (Washington, District of Columbia)
ABSTRACT This disclosure provides systems and methods for sequencing nucleic acids using nucleotide analogues and translocation of tags from incorporated nucleotide analogues through a nanopore. In aspects, this disclosure is related to composition, method, and system for sequencing a nucleic acid using tag molecules and detection of translocation through a nanopore of tags released from incorporation of the molecule.
FILED Monday, April 01, 2019
APPL NO 16/371646
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/00 (20130101) Original (OR) Class
C07H 19/06 (20130101)
C07H 19/16 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/42 (20130101)
C12Q 1/48 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6883 (20130101)
C12Q 2521/525 (20130101)
C12Q 2521/525 (20130101)
C12Q 2521/543 (20130101)
C12Q 2521/543 (20130101)
C12Q 2535/107 (20130101)
C12Q 2537/157 (20130101)
C12Q 2565/631 (20130101)
C12Q 2565/631 (20130101)
C12Q 2565/631 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/48721 (20130101)
G01N 2333/9125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795201 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Yong-Xu Wang (Southborough, Massachusetts);  Qingbo Chen (Worcester, Massachusetts)
ABSTRACT Methods of treating or reducing the risk of obesity and/or obesity-related disorders, e.g., metabolic syndrome, hepatic and non-hepatic steatosis, and diabetes, using C20orf27 proteins or nucleic acids.
FILED Friday, April 13, 2018
APPL NO 16/604692
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/76 (20130101)
A61K 38/00 (20130101)
A61K 38/17 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)

Peptides
C07K 14/4705 (20130101) Original (OR) Class
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/00 (20130101)
C12N 15/62 (20130101)
C12N 15/86 (20130101)
C12N 15/861 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795211 Sok et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) International AIDS Vaccine Initiative (New York, New York);  The Scripps Research Institute (La Jolla, California);  The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) International AIDS Vaccine Initiative (New York, New York);  The Scripps Research Institute (La Jolla, California);  THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S) Devin Sok (New York, New York);  Dennis R. Burton (La Jolla, California);  Vaughn V. Smider (La Jolla, California);  Ian Wilson (La Jolla, California);  Michael Criscitiello (College Station, Texas);  Waithaka Mwangi (College Station, Texas)
ABSTRACT The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab′)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody.
FILED Thursday, July 12, 2018
APPL NO 16/630768
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/162 (20130101)
C07K 16/1063 (20130101) Original (OR) Class
C07K 2317/10 (20130101)
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/33 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
C07K 2319/02 (20130101)
C07K 2319/31 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795213 Schuppan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Detlef Schuppan (Mainz, Germany);  Yvonne Junker (Kiel, Germany);  Towia Aron Libermann (Chestnut Hill, Massachusetts);  Simon T. Dillon (Danvers, Massachusetts)
ABSTRACT The invention features the treatment of gastrointestinal disorders associated with an innate immune response triggered by alpha amylase inhibitor CM3, alpha amylase inhibitor 0.19 (0.19), CM1, CM2, CMa, CMd, CM 16, CMb, CMX1/CMX3, CMX2, and/or alpha amylase inhibitor 0.53 (0.53). To this end, the invention features pharmaceutical compositions including neutralizing antibodies to CM3, 0.19, CM1, CM2, CMa, CMd, CM16, CMb, CMX1/CMX3, CMX2, and/or 0.53, food products containing reduced levels of CM3, 0.19, CM1, CM2, CMa, CMd, CM1 6, CMb, CMX1/CMX3, CMX2, and/or 0.53 protein, the use of oral TLR4 inhibitors to block the effect of said alpha-amylase inhibitors, assays for identifying CM3, 0.19, CM1, CM2, CMa, CMd, CM16, CMb, CMX1/CMX3, CMX2, and/or 0.53 content in food products, and assays for diagnosing subjects with a disorder related to CM3, 0.19, CM1, CM2, CMa, CMd, CM 16, CMb, CMX1/CMX3, CMX2, and/or 0.53 triggered innate immune responses.
FILED Tuesday, August 01, 2017
APPL NO 15/666030
ART UNIT 1662 — Plants
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/16 (20130101)
C07K 16/18 (20130101) Original (OR) Class
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8218 (20130101)
C12N 15/8245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795217 Hendifar
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S) Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S) Andrew Hendifar (Santa Monica, California)
ABSTRACT A composition for IL-1 inhibition in combination with cancer therapies (e.g., chemotherapeutics including chemotherapy protective drugs) is provided for use in treating pancreatic cancer cachexia in patients, so as to reduce weight loss and improve the quality of life and survival of the patients. In one embodiment, the IL-1 inhibitor is an antibody, such as bermekimab, anakinra, canakinumab, gevokizumab, or rilonacept, administered simultaneously or sequentially with iritenocan, 5-fluorouracil and folinic acid to a pancreatic cancer patient.
FILED Friday, March 19, 2021
APPL NO 17/207272
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/513 (20130101)
A61K 31/519 (20130101)
A61K 31/4745 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/245 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795235 Pastan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Ira H. Pastan (Chevy Chase, Maryland);  Junxia Wei (Rockville, Maryland);  Masanori Onda (Germantown, Maryland);  Tapan Bera (Frederick, Maryland);  Mitchell Ho (Urbana, Maryland)
ABSTRACT Disclosed is a molecule comprising: (a) a first domain, which comprises a targeting moiety; (b) a second domain, which comprises an albumin binding domain (ABD), (c) a third domain, which comprises a furin cleavage sequence (“FCS”), which FCS is cleavable by furin; and (d) a fourth domain, which comprises an optionally substituted Domain III from Pseudomonas exotoxin A (“PE”). Related nucleic acids, recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, methods of producing the molecule, methods of treating or preventing cancer in a mammal, and methods of inhibiting the growth of a target cell are also disclosed.
FILED Tuesday, September 18, 2018
APPL NO 16/648369
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/21 (20130101)
C07K 16/30 (20130101) Original (OR) Class
C07K 16/2803 (20130101)
C07K 16/2866 (20130101)
C07K 16/2878 (20130101)
C07K 2317/31 (20130101)
C07K 2317/73 (20130101)
C07K 2317/94 (20130101)
C07K 2317/569 (20130101)
C07K 2317/624 (20130101)
C07K 2319/33 (20130101)
C07K 2319/50 (20130101)
C07K 2319/55 (20130101)
C07K 2319/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795443 Liu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  Beam Therapeutics Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  Beam Therapeutics, Inc. (Cambridge, Massachusetts)
INVENTOR(S) David R. Liu (Cambridge, Massachusetts);  Nicole Marie Gaudelli (Cambridge, Massachusetts);  Michael S. Packer (Cambridge, Massachusetts);  Gregory Newby (Cambridge, Massachusetts)
ABSTRACT The disclosure provides methods and compositions for treating blood diseases/disorders, such as sickle cell disease, hemochromatosis, hemophilia, and beta-thalassemia. For example the disclosure provides therapeutic guide RNAs that target the promotor of HBG1/2 to generate point mutations that increase expression of fetal hemoglobin. As another example, the disclosure provides therapeutic guide RNAs that target mutations in HBB, Factor VIII, and HFE to treat sickle cell disease, beta-thalassemia, hemophilia and hemochromatosis. The disclosure also provides fusion proteins comprising a Cas9 (e.g., a Cas9 nickase) domain and adenosine deaminases that deaminate adenosine in DNA. In some embodiments, the fusion proteins are in complex with nucleic acids, such as guide RNAs (gRNAs), which target the fusion proteins to a DNA sequence (e.g., an HBG1 or HBG2 protmoter sequence, or an HFE, GBB, or F8 gene sequence). Such complexes may be useful for increasing expression of fetal hemoglobin or correcting a poing mutation (e.g., C282Y) in HFE.
FILED Tuesday, October 16, 2018
APPL NO 16/756432
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/78 (20130101) Original (OR) Class
C12N 15/11 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)

Enzymes
C12Y 305/04004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795452 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David R. Liu (Cambridge, Massachusetts);  Andrew Vito Anzalone (Cambridge, Massachusetts)
ABSTRACT Compositions and methods are provided herein for conducting prime editing of a target DNA molecule (e.g., a genome) that enables the incorporation of a nucleotide change and/or targeted mutagenesis. The compositions include fusion proteins comprising nucleic acid programmable DNA binding proteins (napDNAbp) and a polymerase (e.g., reverse transcriptase), which is guided to a specific DNA sequence by a modified guide RNA, named a PEgRNA. The PEgRNA has been altered (relative to a standard guide RNA) to comprise an extended portion that provides a DNA synthesis template sequence which encodes a single strand DNA flap which is synthesized by the polymerase of the fusion protein and which becomes incorporated into the target DNA molecule.
FILED Monday, May 23, 2022
APPL NO 17/751599
ART UNIT 1699 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/001 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/1276 (20130101)
C12N 15/11 (20130101) Original (OR) Class
C12N 15/62 (20130101)
C12N 15/902 (20130101)
C12N 15/907 (20130101)
C12N 2310/20 (20170501)
C12N 2310/3517 (20130101)
C12N 2310/3519 (20130101)
C12N 2800/80 (20130101)

Enzymes
C12Y 207/07049 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795455 Weiss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ron Weiss (Newton, Massachusetts);  Breanna E. DiAndreth (Cambridge, Massachusetts)
ABSTRACT Provided herein are genetic circuits and encoded RNA transcripts that produce an output molecule in response to an RNA cleavage event that removes a degradation signal. In some embodiments, the genetic circuits described herein may be used for detecting RNA cleaver activities (e.g., in a cell). Methods of using the genetic circuits described herein in diagnostic or therapeutic applications are also provided.
FILED Monday, July 30, 2018
APPL NO 16/049042
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/0066 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101)
C12N 15/67 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/121 (20130101)
C12N 2310/122 (20130101)
C12N 2310/126 (20130101)
C12N 2840/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795457 Corey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Regents of The University of Texas System (Austin, Texas)
ASSIGNEE(S) The Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) David Corey (Dallas, Texas);  Liande Li (Dallas, Texas)
ABSTRACT Described are compounds and methods useful for the treatment and investigation of Friedreich's Ataxia.
FILED Monday, September 27, 2021
APPL NO 17/486136
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/315 (20130101)
C12N 2310/3231 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795459 Place et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) miRecule, Inc. (Gaithersburg, Maryland)
ASSIGNEE(S) MIRECULE, INC. (Gaithersburg, Maryland)
INVENTOR(S) Robert Place (Gaithersburg, Maryland);  Anthony Saleh (Gaithersburg, Maryland);  Tishan Williams (Gaithersburg, Maryland)
ABSTRACT Disclosed herein are engineered oligonucleotides for selective inhibition of polypeptide expression and activity. Also disclosed herein are methods of selectively inhibiting polypeptide expression and activity contacting an engineered oligonucleotide with a polynucleotide encoding the polypeptide.
FILED Friday, March 11, 2022
APPL NO 17/692630
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 47/549 (20170801)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/33 (20130101)
C12N 2310/141 (20130101)
C12N 2310/316 (20130101)
C12N 2310/321 (20130101)
C12N 2310/322 (20130101)
C12N 2310/351 (20130101)
C12N 2310/531 (20130101)
C12N 2310/3521 (20130101)
C12N 2320/31 (20130101)
C12N 2320/32 (20130101)
C12N 2320/35 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795464 Harvey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Colin Harvey (Mountain View, California);  Ulrich Schlecht (Sunnyvale, California);  Maureen Elizabeth Hillenmeyer (Palo Alto, California)
ABSTRACT Inducible promoters for the coordinated expression of at least one heterologous gene in yeast and methods of using them are disclosed. In particular, the invention relates to sets of inducible promoters derived from S. cerevisiae and related species that can be induced in the presence of nonfermentable carbon sources.
FILED Thursday, February 20, 2020
APPL NO 16/796851
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/81 (20130101) Original (OR) Class
C12N 15/635 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795510 McDonald et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland);  Memorial Sloan Kettering Cancer Center (New York, New York);  Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  Memorial Sloan Kettering Cancer Center (New York, New York);  Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Oliver McDonald (Baltimore, Maryland);  Xin Li (Baltimore, Maryland);  Christine A. Iacobuzio-Donahue (Baltimore, Maryland);  Andrew P. Feinberg (Baltimore, Maryland)
ABSTRACT The present invention relates to a method of identifying epigenetic reprogramming. Identifying epigenetic reprogramming comprises detecting large organized heterochromatin lysine (K)-9 modified domains (LOCKs) and large DNA hypomethylated blocks in a sample containing DNA from a subject having cancer, for example, PDAC.
FILED Thursday, October 05, 2017
APPL NO 16/340069
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)
A61P 43/00 (20180101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57484 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795511 Carroll et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) NEW YORK UNIVERSITY (New York, New York)
ASSIGNEE(S) NEW YORK UNIVERSITY (New York, New York)
INVENTOR(S) William L. Carroll (Irvington, New York);  Julia A. Meyer (New York, New York)
ABSTRACT The present invention is directed to methods of prognosing relapsed leukemia in a subject. These methods are based on the detection of one or more relapse-specific gene mutations in a patient sample. The present invention further relates to methods of preventing and treating relapse leukemia in a subject based on the determined prognosis of the subject.
FILED Tuesday, July 21, 2020
APPL NO 16/934850
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/52 (20130101)
A61K 31/573 (20130101)
A61K 31/704 (20130101)
A61K 31/7068 (20130101)
A61K 45/06 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795512 Czerniak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Bogdan Czerniak (Houston, Texas);  Keith Baggerly (Houston, Texas);  Jolanta Bondaruk (Houston, Texas);  Tadeusz Majewski (Houston, Texas);  Colin Dinney (Houston, Texas);  Shizhen Zhang (Houston, Texas);  Yan Wang (Houston, Texas)
ABSTRACT The present disclosure provides methods and compositions for the detection of bladder in a subject using four locus-specific probes to 6p22, 8q22, 11q13, and 20p11.2.
FILED Wednesday, January 30, 2019
APPL NO 16/965409
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6841 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796472 He et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
Division of Materials Research (DMR)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chen He (Chicago, Illinois);  David J. Weinberg (San Diego, California);  Emily A. Weiss (Evanston, Illinois);  Jeremiah Yoonsung Kim (Glenview, Illinois);  Chen Wang (Evanston, Illinois);  Andrew Lee (Evanston, Illinois)
ABSTRACT The present technology is directed to the nanoparticles for use as molecular environmental sensors. The nanoparticles comprise a photoluminescence core and a plurality of ligands bound to the core and forming a quencher permeable ligand shell. The ligands comprise a reactive or charged moiety capable of being modulated between a first stand and a second state, and the proportion of ligands in each state determine the permeability of the ligand shell to a photoluminescence quencher.
FILED Tuesday, October 19, 2021
APPL NO 17/505392
ART UNIT 1796 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 20/00 (20130101)
B82Y 40/00 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 21/21 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2004/64 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101) Original (OR) Class
G01N 21/6489 (20130101)
G01N 2021/6432 (20130101)

Organic electric solid-state devices
H10K 50/115 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796499 Xiao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Science Foundation (NSF)
APPLICANT(S) Yi Xiao (Cary, North Carolina);  Yingzhu Liu (Wuhan, China PRC);  Juan Canoura (Hialeah Gardens, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Yi Xiao (Cary, North Carolina);  Yingzhu Liu (Wuhan, China PRC);  Juan Canoura (Hialeah Gardens, Florida)
ABSTRACT The subject invention provides methods for fabricating electrochemical aptamer-based (E-AB) sensors with enhanced sensitivity, signal-to-noise ratios, LOD, and improved stability and reproducibility. The subject invention also provides methods for aptamer immobilization on the surface of the electrode, which favors sufficient spacing between aptamers at the microscale to achieve optimal target recognition, folding, and signal transduction. The E-AB sensors of the subject invention provide superior sensing regardless of the sequence or structure of the bound aptamers or the physiochemical properties of the target.
FILED Tuesday, December 13, 2022
APPL NO 18/065118
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3276 (20130101) Original (OR) Class
G01N 27/3277 (20130101)
G01N 33/5308 (20130101)
G01N 33/5438 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796504 Ibrahim et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Yehia M. Ibrahim (West Richland, Washington);  Adam L. Hollerbach (Richland, Washington);  Ailin Li (Richland, Washington)
ABSTRACT An apparatus includes multiple levels of ion transport channels, with successive levels coupled by elevator channels. Efficient three dimensional packing provides long path lengths in practical volumes for ion mobility separation with high resolving power. Disclosed elevator configurations provide efficient routing of ion transport channels across levels with low ion loss, enabling ion mobility separation over 100 levels or more. Elevator configurations include (i) opposed traveling waves meeting at an elevator entrance, (ii) external elevator with a wrap-around electrode bank, (iii) external elevator with electrode banks on parallel extension plates, or (iv) elevator operating in surfing mode, in various combinations. Manufacture is aided by printed wiring boards, with interchangeable boards. Assembly with motherboard, spacer block(s), and alignment pins provides efficient distribution of electrode excitations and accurate reproducible positioning.
FILED Wednesday, August 11, 2021
APPL NO 17/399629
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/68 (20130101)
G01N 27/622 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 49/061 (20130101)
H01J 49/062 (20130101)
H01J 49/4225 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796615 Viessmann et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Mental Health (NIMH)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Olivia M. Viessmann (Cambridge, Massachusetts);  Jonathan R. Polimeni (Cambridge, Massachusetts);  Bruce Fischl (Cambridge, Massachusetts)
ABSTRACT Anatomical, physiological, instrumental, and other related biases are removed from functional magnetic resonance imaging (“fMRI”) signal data using deep learning algorithms and/or models, such as a neural network. Bias characterization data are used as an auxiliary input to the neural network. The bias characterization data can be subject-specific bias characterization data (e.g., cortical thickness maps, cortical orientation angle maps, vasculature maps), hardware-specific bias characterization data (e.g., coil sensitivity maps, coil transmission profiles), or both. The subject-specific bias characterization data can be extracted from the fMRI signal data using a second neural network. The bias-reduced fMRI signal data can include time-series signals, functional activation maps, functional connectivity maps, or combinations thereof.
FILED Monday, April 18, 2022
APPL NO 17/659599
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4806 (20130101) Original (OR) Class
G01R 33/5608 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/045 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796789 Jiang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Hongrui Jiang (Madison, Wisconsin);  Alireza Ousati Ashtiani (Madison, Wisconsin)
ABSTRACT A light modulator and method of forming the same is provided. The light modulator includes a membrane and a tuning electrode in spaced relation to the membrane. A light blocking fluid is received between the substrate and the tuning electrode and a light blocker is positioned between the tuning electrode and a central portion of the membrane. A pinning electrode is disposed between the light blocker and the membrane and is aligned with the central portion of the membrane. An electrostatic generator is configured to selectively apply an electrostatic force on the membrane causing the central portion of the membrane to deform towards pinning electrode causing the light blocking fluid to be displaced from between the membrane and the pinning electrode. A variable electrostatic generator is configured to selectively apply a variable electrostatic force on the membrane causing an outer portion of the membrane to deform towards the tuning electrode and causing the light blocking fluid to be displaced from between the outer portion of the membrane and the tuning electrode.
FILED Tuesday, September 01, 2020
APPL NO 17/009231
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 26/02 (20130101) Original (OR) Class
G02B 26/004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796798 Gopinath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Juliet Gopinath (Boulder, Colorado);  Mo Zohrabi (Boulder, Colorado);  Victor M. Bright (Boulder, Colorado);  Omkar Supekar (Boulder, Colorado);  Robert H. Cormack (Erie, Colorado);  Emily Gibson (Boulder, Colorado);  Connor McCullough (Denver, Colorado)
ABSTRACT The present disclosure relates generally to methods and systems useful in imaging applications, especially biological imaging applications, and applications in the metrology, atmospheric, scientific and medical fields. In one aspect, the disclosure provides a method of imaging an object, including illuminating the object with incident radiation through one or more adaptive optical elements; receiving transmitted radiation from the object at a photodetector to provide a base image; and performing the following steps one or more times: adjusting the one or more adaptive optical elements, the adjustment including modifying an optical transfer function of the one or more adaptive optical elements, and receiving transmitted radiation from the object at the photodetector to provide an adjusted image; wherein the adjustment and receiving steps are performed until the adjusted image has substantially reduced aberrations compared to the base image.
FILED Wednesday, October 03, 2018
APPL NO 16/753615
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101)
G02B 27/0068 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797337 Birnbaum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Leica Microsystems CMS GmbH (Wetzlar, Germany)
ASSIGNEE(S) Leica Microsystems CMS GmbH (Wetzlar, Germany)
INVENTOR(S) Christopher Birnbaum (Issaquah, Washington);  Shih-Jong James Lee (Bellevue, Washington);  Tuan Phan (Lynnwood, Washington)
ABSTRACT A computerized efficient data processing management method for imaging applications first performs a data flow graph generation by computing means using at least one image data and at least one requested task to generate a data flow graph. The method then applies a task execution scheduling using the data flow graph generated, a caching system configuration, the at least one image data and at least one requested task to schedule execution of the at least one requested task to generate task execution output. In addition, an adaptive data processing method performs caching system update and an optimal data processing method further performs data flow graph update.
FILED Friday, August 21, 2020
APPL NO 17/000174
ART UNIT 2195 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/3005 (20130101)
G06F 9/4881 (20130101) Original (OR) Class
G06F 9/5061 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798179 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Eye Institute (NEI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Jacob Antunes (Cincinnati, Ohio);  Zhouping Wei (Cleveland, Ohio);  Pallavi Tiwari (Wexford, Pennsylvania);  Satish E. Viswanath (Pepper Pike, Ohio);  Charlems Alvarez Jimenez (Bogotá, Colombia)
ABSTRACT The present disclosure, in some embodiments, relates to a non-transitory computer-readable medium storing computer-executable instructions. The computer readable medium is configured to cause a processor to access an image volume of a rectum comprising a rectal tumor. A forward mapping is generated based on non-rigidly registering a healthy rectal atlas to the image volume. The forward mapping is inverted to generate an inverse mapping from the image volume to the healthy rectal atlas. Based on the inverse mapping, a plurality of deformation vectors, associated with a deformation within a rectal wall of the rectum, are determined. Magnitude based deformation features and orientation based deformation features are computed from the plurality of deformation vectors. One or more of the magnitude based deformation features and one or more of the orientation based deformation features are utilized to determine a response of a patient to a chemoradiation treatment.
FILED Wednesday, September 22, 2021
APPL NO 17/481625
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/33 (20170101) Original (OR) Class
G06T 7/38 (20170101)
G06T 2207/10088 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
G16H 50/70 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798654 Kumar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Sumesh Kumar (Miami, Florida);  Fahad Saeed (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Sumesh Kumar (Miami, Florida);  Fahad Saeed (Miami, Florida)
ABSTRACT Systems, architectures, devices, and methods for matching experimentally acquired mass spectrometry data with a peptide database are provided. The system architecture can include a host central processing unit (CPU) system, a bridge connecting the CPU system with a core control register (or registers), a plurality of processing elements (PEs), and a bus arbiter. The PEs can execute the computations in a parallel and asynchronous manner. The bus arbiter can be a first-come first-serve (FCFS)-based bus arbiter (i.e., can utilize an FCFS-based arbitration scheme).
FILED Thursday, July 28, 2022
APPL NO 17/815814
ART UNIT 1672 — Selective Visual Display Systems
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/62 (20130101)
G01N 33/6848 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 40/10 (20190201)
G16B 50/30 (20190201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798656 Ryu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Nevada Research and Innovation Corporation (Reno, Nevada)
ASSIGNEE(S) Nevada Research and Innovation Corporation (Reno, Nevada)
INVENTOR(S) So Young Ryu (Reno, Nevada)
ABSTRACT One aspect of the invention provides a computer-implemented method of identifying a species from mass spectra. The computer-implemented method includes: loading a data set including a species and associated mass spectra into memory on a computer; for each of the associated mass spectra, pre-processing to identify ranks of intensities of an in-bin peak across bins defining ranges of mass-to-charge ratio; and training a species binary classifier for each of a plurality of species using at least the ranks of intensities. Another aspect of the invention provides a system for identifying a species from mass spectra. The system includes: a processor; and computer-readable memory containing instructions to: implement an interface programmed to receive mass spectra; store the mass spectra in the computer-readable memory; and invoke execution of any of the methods described herein on the processor.
FILED Tuesday, January 21, 2020
APPL NO 16/748315
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/20 (20190201) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 49/0036 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE49708 Prendergast et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) LANKENAU INSTITUTE FOR MEDICAL RESEARCH (Wynnewood, Pennsylvania)
ASSIGNEE(S) LANKENAU INSTITUTE FOR MEDICAL RESEARCH (Wynnewood, Pennsylvania)
INVENTOR(S) George C. Prendergast (Penn Valley, Pennsylvania);  Richard Metz (Pennington, New Jersey)
ABSTRACT The nucleotide and amino acid sequences of indoleamine 2,3-dioxygenase-2 (IDO2) and methods of use thereof are provided.
FILED Friday, January 08, 2021
APPL NO 17/145002
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0276 (20130101)

Peptides
C07K 2319/21 (20130101)
C07K 2319/40 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0069 (20130101) Original (OR) Class
C12N 2830/006 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11793982 Lee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana);  Industry-University Cooperation Foundation Hanyang University (Seoul, South Korea)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana);  Industry-University Cooperation Foundation Hanyang University (Seoul, South Korea)
INVENTOR(S) Chi Hwan Lee (West Lafayette, Indiana);  Yoon Yeo (West Lafayette, Indiana);  Dong Rip Kim (Seoul, South Korea)
ABSTRACT Drug delivery devices that have a flexible film, an array of nanoscopic, porous needles attached to a surface of the flexible film, and a therapeutic drug cargo loaded onto the needles. The drug delivery device may be applied to living tissue such that the surface of the flexible film contacts the living tissue and some or all of the needles are inserted into the tissue. The flexible film may then be dissolved while leaving the needles inserted in the tissue. The needles degrade in the living tissue over time causing release of the therapeutic drug cargo loaded onto the needles.
FILED Thursday, June 10, 2021
APPL NO 17/344362
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0015 (20130101) Original (OR) Class
A61M 2037/0023 (20130101)
A61M 2037/0053 (20130101)
A61M 2205/0244 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794140 Peterson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
APPLICANT(S) Combat Capabilities Development Command, Chemical Biological Center (APG, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Gregory Peterson (Bel Air, Maryland);  Ryan Ballantyne (Columbus, Ohio);  Michael Boruch (Fredericksburg, Virginia);  William Clark (Fredericksburg, Virginia);  Bruce Corso (Fredericksburg, Virginia);  William B Feaver (Columbus, Ohio);  Nicole Puckace (Darlington, Maryland);  Jeffery Stephen Hoene (Churchville, Maryland);  Joseph Hunt (King George, Virginia);  Neil Kennihan (Dahlgre, Virginia);  Craig LaMoy (King George, Virginia);  Robert Kinter (Waldorf, Maryland);  Michael J Knapke (Plain City, Ohio);  Mark Noltimier (Columbus, Ohio);  Michael Pompeii (Fredericksburg, Virginia);  Chris Ritchey (Bel Air, Maryland);  Joseph A Rossin (Columbus, Ohio);  Rachel L Rossin (Ashville, Ohio);  Richard Warder, Jr (King George, Virginia)
ABSTRACT A process and device for enhancing the chemical protection capability of a collective protection filter whereby the process stream exiting the collective protection filter is passed through an Auxiliary Filter. The auxiliary filter containing an ammonia removal media, such as zirconium hydroxide impregnated with zinc chloride (ZnCl2/Zr(OH)4), an oxidizing media, preferably zirconium hydroxide impregnated with potassium permanganate (KMnO4/Zr(OH)4), and a methyl bromide removal media, preferably activated carbon impregnated with triethylenediamine (TEDA/carbon). The auxiliary filter and process are configured to remove toxic industrial chemicals including NH3, NOx (mixtures of NO and NO2) and CH2O, and CH3Br.
FILED Monday, May 18, 2020
APPL NO 16/877033
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 29/52 (20130101)
B01D 37/025 (20130101)
B01D 46/0036 (20130101) Original (OR) Class
B01D 46/56 (20220101)
B01D 2251/502 (20130101)
B01D 2251/504 (20130101)
B01D 2251/506 (20130101)
B01D 2251/602 (20130101)
B01D 2251/604 (20130101)
B01D 2252/20431 (20130101)

Compositions of Macromolecular Compounds
C08L 67/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794188 Han et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
ASSIGNEE(S) THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S) Arum Han (College Station, Texas);  Adrian Guzman (College Station, Texas);  Han Zhang (College Station, Texas);  Jose Wippold (College Station, Texas);  Jing Dai (College Station, Texas)
ABSTRACT A combination micro/macro-fluidic analysis system with one or more of a droplet transition unit, a droplet cleaving unit, a droplet synchronization, and a merging unit to enable highly efficient complex droplet microfluidic assays.
FILED Friday, April 23, 2021
APPL NO 17/239456
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502784 (20130101) Original (OR) Class
B01L 2200/12 (20130101)
B01L 2200/16 (20130101)
B01L 2200/027 (20130101)
B01L 2200/0647 (20130101)
B01L 2400/086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794242 McNabb et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Montana Technological University (Butte, Montana)
ASSIGNEE(S) Montana Technological University (Butte, Montana)
INVENTOR(S) Riley Leonard McNabb (Butte, Montana);  Peter Andrew Lucon (Butte, Montana);  Nathan James Huft (Butte, Montana);  T Oscar Winsor (Shoreline, Washington)
ABSTRACT The present disclosure provides a blended powder comprising a first ferroalloy powder and at least one iron powder or second ferroalloy powder. The present disclosure also provides a method for dry metal alloying, comprising combining powder comprising a first ferroalloy powder and at least one iron powder or second ferroalloy powder, and mixing the combined powders to form a blended powder.
FILED Thursday, August 12, 2021
APPL NO 17/401258
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/065 (20220101) Original (OR) Class
B22F 10/28 (20210101)
B22F 2301/15 (20130101)
B22F 2301/35 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794254 Hoy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Non-Profit Organization (NPO)
National Center for Manufacturing Sciences Inc. (NCMS)
APPLICANT(S) 3D Systems, Inc. (Rock Hill, South Carolina)
ASSIGNEE(S) 3D SYSTEMS, INC. (Rock Hill, South Carolina)
INVENTOR(S) Ahren Michael Hoy (Charlotte, North Carolina);  Turner Ashby Cathey (Rock Hill, South Carolina);  Alexander J Geyling (Fort Mill, South Carolina)
ABSTRACT An additive manufacturing system for producing a three-dimensional article includes a print engine, a post-fabrication powder removal apparatus, a transport mechanism, and a controller. The post fabrication removal apparatus includes a rotary frame defining an internal receptacle cavity, a plurality of clamps coupled to a corresponding plurality of actuators, a clamping plate coupled to a lift apparatus, and an agitation device mounted to the clamping plate. The controller is configured to perform the following steps: (1) Operate the transport mechanism to transport the build box to the internal receptacle cavity. (2) Operate the plurality of actuators to engage the build box with the plurality of clamps to secure the build box to the rotary frame. (3) Operate the rotary frame to rotate the build box until unfused powder begins to exit the build box. (4) Operate the agitation device to facilitate pouring of the unfused powder from the build box.
FILED Friday, February 03, 2023
APPL NO 18/163956
ART UNIT 2853 — Printing/Measuring and Testing
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/28 (20210101)
B22F 10/68 (20210101) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 40/20 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794334 Okamura et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Allison M. Okamura (Mountain View, California);  Sean Follmer (Palo Alto, California);  Elliot W. Hawkes (Santa Barbara, California);  Zachary Hammond (Stanford, California);  Nathan Scot Usevitch (Stanford, California);  Mac Schwager (Stanford, California);  James Ballard (Menlo Park, California)
ABSTRACT Adaptable and customizable truss-like robots are provided. The robotic truss has robotic roller modules configured to translate along one or more pliable member and therewith control the shape or design of the robot.
FILED Thursday, September 10, 2020
APPL NO 17/017299
ART UNIT 2846 — Printing/Measuring and Testing
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/08 (20130101)
B25J 9/0012 (20130101)
B25J 9/0075 (20130101) Original (OR) Class
B25J 9/126 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794353 Khripin et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Defense Contract Management Agency (DCMA)
Department of the Army (DOA)
APPLICANT(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Boston Dynamics, Inc. (Waltham, Massachusetts)
INVENTOR(S) Alex Khripin (Waltham, Massachusetts);  Stephen Berard (Waltham, Massachusetts);  Alfred Rizzi (Cambridge, Massachusetts)
ABSTRACT An example robot includes a hydraulic actuator cylinder controlling motion of a member of the robot. The hydraulic actuator cylinder comprises a piston, a first chamber, and a second chamber. A valve system controls hydraulic fluid flow between a hydraulic supply line of pressurized hydraulic fluid, the first and second chambers, and a return line. A controller may provide a first signal to the valve system so as to begin moving the piston based on a trajectory comprising moving in a forward direction, stopping, and moving in a reverse direction. The controller may provide a second signal to the valve system so as to cause the piston to override the trajectory as it moves in the forward direction and stop at a given position, and then provide a third signal to the valve system so as to resume moving the piston in the reverse direction based on the trajectory.
FILED Thursday, October 21, 2021
APPL NO 17/451669
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 5/00 (20130101)
B25J 9/20 (20130101) Original (OR) Class

Motor Vehicles; Trailers
B62D 57/032 (20130101)

Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for
F15B 9/09 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 901/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794881 Rubin
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) United States of America, as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Stuart H. Rubin (San Diego, California)
ABSTRACT A maritime vehicle includes a surface for contacting a fluid medium through which the maritime vehicle is propelled. The maritime vehicle also includes an array of transducers and a controller. The transducers in the array are arranged across the maritime vehicle's surface for generating pressure waves in the fluid medium. Each transducer in the array is arranged to vibrate for generating a respective pressure wave, which propagates away from the surface in the fluid medium. The controller vibrates the transducers in the array so that the pressure waves control the drag of the maritime vehicle from the fluid medium.
FILED Tuesday, August 02, 2022
APPL NO 17/879128
ART UNIT 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 1/34 (20130101)
B63B 1/36 (20130101)

Aeroplanes; Helicopters
B64C 23/005 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794887 DiPalma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
ASSIGNEE(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
INVENTOR(S) Matthew Walter DiPalma (Bridgeport, Connecticut);  Timothy James Conti (Shelton, Connecticut);  Claude George Matalanis (Monroe, Connecticut)
ABSTRACT A rotor blade assembly for a rotary wing aircraft includes a main rotor blade body comprising an upper blade skin, a lower blade skin, an inboard end, an outboard end, and a trailing edge. The rotor blade assembly further includes a trailing edge actuator assembly. The trailing edge actuator assembly includes an upper actuator skin and a lower actuator skin defining a cavity and a trailing edge flap, a control panel disposed in the cavity and coupled to one of the upper actuator skin or the lower actuator skin and one or more actuators disposed in the cavity and configured to apply force to the control panel to cause the trailing edge flap to deflect. The trailing edge actuator assembly is coupled to the trailing edge of the main rotor blade body.
FILED Wednesday, April 06, 2022
APPL NO 17/714572
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/57 (20130101)
B64C 27/64 (20130101)
B64C 27/467 (20130101) Original (OR) Class
B64C 27/473 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794930 McGann et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Shawn Kerry McGann (Ridgecrest, California);  Nicholas McGaha (Ridgecrest, California)
ABSTRACT An unmanned aerial vehicle (UAV) jettison apparatus. The UAV jettison apparatus may comprise a payload bay, fairing, ejector plate, and releasable latch. The payload bay may be mounted beneath an aircraft and may have an inner space and a top plate attached therewith. The fairing may substantially cover the inner space of the payload bay and may have an opening positioned directly below the top plate. The ejector plate, which may be spring-loaded, may substantially cover the opening and may be used to mount the UAV. The releasable latch, which may be disposed between the top plate and the ejector plate, may releasably lock and hold the UAV in a stowed position and, upon release, may allow the ejector plate to move into a launch position, such that the UAV is released and jettisoned from a larger aircraft.
FILED Tuesday, August 10, 2021
APPL NO 17/398274
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 5/00 (20130101)

Unmanned aerial vehicles [UAV]; equipment therefor
B64U 10/14 (20230101) Original (OR) Class
B64U 70/20 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795208 Doudna et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A Doudna (Berkeley, California);  Kyle E. Watters (Moraga, California);  Christof Fellmann (Berkeley, California);  Haridha Shivram (Berkeley, California)
ABSTRACT The present disclosure provides polypeptides that inhibit activity of a CRISPR/Cas effector polypeptide, nucleic acids encoding the polypeptides, and systems comprising the polypeptides and/or nucleic acids encoding the polypeptides. The present disclosure provides methods of inhibiting activity of a CRISRP/Cas effector polypeptide.
FILED Wednesday, September 30, 2020
APPL NO 17/039195
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/8107 (20130101) Original (OR) Class
C07K 2319/09 (20130101)
C07K 2319/40 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795212 Ingber et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Donald E. Ingber (Boston, Massachusetts);  Michael Super (Lexington, Massachusetts);  Jeffrey Charles Way (Cambridge, Massachusetts);  Mark J. Cartwright (West Newton, Massachusetts);  Julia B. Berthet (Brookline, Massachusetts);  Dinah R. Super (Lexington, Massachusetts);  Martin Rottman (St. Cloud, France);  Alexander L. Watters (Melrose, Massachusetts)
ABSTRACT Described herein are engineered microbe-targeting or microbe-binding molecules, kits comprising the same and uses thereof. Some particular embodiments of the microbe-targeting or microbe-binding molecules comprise a carbohydrate recognition domain of mannose-binding lectin, or a fragment thereof, linked to a portion of a Fc region. In some embodiments, the microbe-targeting molecules or microbe-binding molecules can be conjugated to a substrate, e.g., a magnetic microbead, forming a microbe-targeting substrate (e.g., a microbe-targeting magnetic microbead). Such microbe-targeting molecules and/or substrates and the kits comprising the same can bind and/or capture of a microbe and/or microbial matter thereof, and can thus be used in various applications, e.g., diagnosis and/or treatment of an infection caused by microbes such as sepsis in a subject or any environmental surface. Microbe-targeting molecules and/or substrates can be regenerated after use by washing with a low pH buffer or buffer in which calcium is insoluble.
FILED Tuesday, November 10, 2020
APPL NO 17/093781
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/68 (20170801)
A61K 47/6815 (20170801)

Peptides
C07K 14/42 (20130101)
C07K 16/12 (20130101) Original (OR) Class
C07K 2319/33 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54353 (20130101)
G01N 33/56911 (20130101)
G01N 33/56916 (20130101)
G01N 33/56938 (20130101)
G01N 33/56961 (20130101)
G01N 2333/42 (20130101)
G01N 2333/4724 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795235 Pastan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Ira H. Pastan (Chevy Chase, Maryland);  Junxia Wei (Rockville, Maryland);  Masanori Onda (Germantown, Maryland);  Tapan Bera (Frederick, Maryland);  Mitchell Ho (Urbana, Maryland)
ABSTRACT Disclosed is a molecule comprising: (a) a first domain, which comprises a targeting moiety; (b) a second domain, which comprises an albumin binding domain (ABD), (c) a third domain, which comprises a furin cleavage sequence (“FCS”), which FCS is cleavable by furin; and (d) a fourth domain, which comprises an optionally substituted Domain III from Pseudomonas exotoxin A (“PE”). Related nucleic acids, recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, methods of producing the molecule, methods of treating or preventing cancer in a mammal, and methods of inhibiting the growth of a target cell are also disclosed.
FILED Tuesday, September 18, 2018
APPL NO 16/648369
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/21 (20130101)
C07K 16/30 (20130101) Original (OR) Class
C07K 16/2803 (20130101)
C07K 16/2866 (20130101)
C07K 16/2878 (20130101)
C07K 2317/31 (20130101)
C07K 2317/73 (20130101)
C07K 2317/94 (20130101)
C07K 2317/569 (20130101)
C07K 2317/624 (20130101)
C07K 2319/33 (20130101)
C07K 2319/50 (20130101)
C07K 2319/55 (20130101)
C07K 2319/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795281 Jiang et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S) Peng Jiang (Gainesville, Florida);  Sin-Yen Leo (Hillsboro, Oregon);  Calen Leverant (Gainesville, Florida);  Danielle Liu (Nashville, Tennessee);  Yin Fang (Gainesville, Florida)
ABSTRACT Described herein are methods and compositions relating to tunable nanoporous coatings. In certain aspects, described herein are methods and compositions wherein a tunable nanoporous coating comprises a tunable nanoporous membrane which transitions from opaque to transparent upon the application of force, and from transparent to opaque after washing with a solvent.
FILED Wednesday, April 14, 2021
APPL NO 17/230160
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Separation
B01D 69/125 (20130101)
B01D 71/40 (20130101)
B01D 2321/18 (20130101)
B01D 2323/24 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 22/1006 (20200201)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101) Original (OR) Class
C08J 7/02 (20130101)
C08J 2335/02 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/111 (20130101)
G02B 5/0247 (20130101)
G02B 5/0268 (20130101)
G02B 5/0294 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795443 Liu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  Beam Therapeutics Inc. (Cambridge, Massachusetts)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  Beam Therapeutics, Inc. (Cambridge, Massachusetts)
INVENTOR(S) David R. Liu (Cambridge, Massachusetts);  Nicole Marie Gaudelli (Cambridge, Massachusetts);  Michael S. Packer (Cambridge, Massachusetts);  Gregory Newby (Cambridge, Massachusetts)
ABSTRACT The disclosure provides methods and compositions for treating blood diseases/disorders, such as sickle cell disease, hemochromatosis, hemophilia, and beta-thalassemia. For example the disclosure provides therapeutic guide RNAs that target the promotor of HBG1/2 to generate point mutations that increase expression of fetal hemoglobin. As another example, the disclosure provides therapeutic guide RNAs that target mutations in HBB, Factor VIII, and HFE to treat sickle cell disease, beta-thalassemia, hemophilia and hemochromatosis. The disclosure also provides fusion proteins comprising a Cas9 (e.g., a Cas9 nickase) domain and adenosine deaminases that deaminate adenosine in DNA. In some embodiments, the fusion proteins are in complex with nucleic acids, such as guide RNAs (gRNAs), which target the fusion proteins to a DNA sequence (e.g., an HBG1 or HBG2 protmoter sequence, or an HFE, GBB, or F8 gene sequence). Such complexes may be useful for increasing expression of fetal hemoglobin or correcting a poing mutation (e.g., C282Y) in HFE.
FILED Tuesday, October 16, 2018
APPL NO 16/756432
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/78 (20130101) Original (OR) Class
C12N 15/11 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)

Enzymes
C12Y 305/04004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795448 Ismagilov et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Defense Threat Reduction Agency (DTRA)
Joint Program Executive Office for Chemical, Biological, Radiological and Nuclear Defense (JPEO-CBRND)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Rustem Ismagilov (Altadena, California);  Erik Jue (Pasadena, California);  Daan Witters (San Diego, California)
ABSTRACT A sample preparation module accepts a sample including a target analyte. The sample preparation module processes the sample through several reaction chambers and a solid phase column. Different reagents are present in the reaction chambers. The eluted analyte is then transferred to the amplification module, where it is further processed and amplified for optical analysis.
FILED Monday, September 13, 2021
APPL NO 17/473832
ART UNIT 1799 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/508 (20130101)
B01L 3/50851 (20130101)
B01L 3/502753 (20130101)
B01L 7/52 (20130101)
B01L 2200/0631 (20130101)
B01L 2200/0689 (20130101)
B01L 2300/04 (20130101)
B01L 2300/18 (20130101)
B01L 2300/069 (20130101)
B01L 2300/0672 (20130101)
B01L 2400/0605 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1003 (20130101) Original (OR) Class
C12N 15/1006 (20130101)
C12N 15/1013 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 21/6456 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795454 Medina-Kauwe
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S) CEDARS-SINAI MEDICAL CENTER (Los Angeles, California)
INVENTOR(S) Lali K. Medina-Kauwe (Porter Ranch, California)
ABSTRACT The present invention relates a targeted delivery system for siRNA or antisense technology. In one embodiment, the invention provides for a method of treating cancer by administering a therapeutically effective dosage of HerPBK10 combined with siRNA, resulting in the inhibition of Her2 expression and cell death. In another embodiment, a plurality of HerPBK10 combined with siRNA form a nanoparticle.
FILED Wednesday, June 10, 2020
APPL NO 16/898264
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/005 (20130101)
C07K 2319/035 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2320/32 (20130101)
C12N 2710/10322 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795456 Bawage et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Swapnil Bawage (Atlanta, Georgia);  Pooja M. Tiwari (Atlanta, Georgia);  Philip J. Santangelo (Atlanta, Georgia)
ABSTRACT Compositions and methods for treating or inactivating viruses in a subject in need thereof are provided herein. Exemplary compositions include nucleic acids encoding an RNA-guided endonuclease and a guide RNA that is complementary to a target sequence in a virus. The RNA-guided endonuclease specifically targets viral nucleic acid sequences for destruction and suppression of that virus in a host cell in vitro or in vivo.
FILED Monday, April 15, 2019
APPL NO 17/047978
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2310/321 (20130101)
C12N 2310/322 (20130101)
C12N 2310/335 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795483 Medintz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Igor L. Medintz (Springfield, Virginia);  Joyce Breger (Greenbelt, Maryland);  Scott Walper (Springfield, Virginia);  Michael H. Stewart (Springfield, Virginia)
ABSTRACT A nanoplatelet serves as a substrate for immobilizing enzymes involved in consecutive reactions as a cascade. This results in a significant increase in the rate of catalysis as well as final product yield compared to non-immobilized enzymes or enzymes immobilized to quantum dots.
FILED Tuesday, June 11, 2019
APPL NO 16/438081
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 15/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 11/02 (20130101)
C12N 11/14 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/56 (20130101) Original (OR) Class

Enzymes
C12Y 102/01012 (20130101)
C12Y 102/02003 (20130101)
C12Y 207/01002 (20130101)
C12Y 207/01011 (20130101)
C12Y 401/02013 (20130101)
C12Y 503/01001 (20130101)
C12Y 503/01009 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795491 Hasan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Tayyaba Hasan (Arlington, Massachusetts);  Ulysses W. Sallum (Quincy, Massachusetts);  Sarika Verma (Waltham, Massachusetts);  Gerard Nau (Sharon, Massachusetts)
ABSTRACT The present invention provides photosensitizer compounds for use in detecting beta-lactamase activity. Methods and kits that utilize the photosensitizer compounds of the invention for the detection of, quantitation of, and classification or typing of microbial beta-lactamases.
FILED Tuesday, November 21, 2017
APPL NO 15/819345
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 501/52 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/04 (20130101)
C12Q 1/34 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/542 (20130101)
G01N 33/56911 (20130101)
G01N 2333/986 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795539 Ehrenberg
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Isaac Mayer Ehrenberg (Brookline, Massachusetts)
ABSTRACT Systems and methods for producing electromagnetic devices are provided. The systems and methods allow for an electromagnetic device having both a substrate (e.g., polymer) and conductive material (e.g., metal) to be manufactured without using masks or other outside objects disposed over a surface (e.g., the substrate) onto which the conductive material is deposited. In one exemplary embodiment, the method includes performing additive manufacturing using a polymer to produce a device having a plurality of interconnected walls and a plurality of frequency selective surface elements, and then coating portions of the device with a conductive material. A plurality of shadowing features are formed as part of one or more of the walls to protect the frequency selective surface elements from being coated by the conductive material. Other methods, and a variety of systems that can result from the disclosed methods, are also provided.
FILED Thursday, October 22, 2020
APPL NO 17/077843
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 80/00 (20141201)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/20 (20130101) Original (OR) Class
C23C 14/044 (20130101)

Antennas, i.e Radio Aerials
H01Q 15/0013 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 3/146 (20130101)
H05K 3/1258 (20130101)
H05K 2201/09036 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795574 Tassev
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Vladimir Tassev (Beavercreek, Ohio)
ABSTRACT A method of performing HVPE heteroepitaxy comprises exposing a substrate to a carrier gas, a first precursor gas, a Group II/III element, and ternary-forming gasses (V/VI group precursor), to form a heteroepitaxial growth of a binary, ternary, and/or quaternary compound on the substrate; wherein the carrier gas is H2, wherein the first precursor gas is HCl, the Group II/III element comprises at least one of Zn, Cd, Hg, Al, Ga, and In; and wherein the ternary-forming gasses comprise at least two or more of AsH3 (arsine), PH3 (phosphine), H2Se (hydrogen selenide), H2Te (hydrogen telluride), SbH3 (hydrogen antimonide, or antimony tri-hydride, or stibine), H2S (hydrogen sulfide), NH3 (ammonia), and HF (hydrogen fluoride); flowing the carrier gas over the Group II/III element; exposing the substrate to the ternary-forming gasses in a predetermined ratio of first ternary-forming gas to second ternary-forming gas (1tf:2tf ratio); and changing the 1tf:2tf ratio over time.
FILED Monday, October 17, 2022
APPL NO 18/046944
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/02 (20130101)
C30B 25/04 (20130101) Original (OR) Class
C30B 25/18 (20130101)
C30B 29/42 (20130101)
C30B 29/44 (20130101)
C30B 29/48 (20130101)
C30B 29/403 (20130101)
C30B 29/406 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3556 (20130101)
G02F 1/3558 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/024 (20130101)
H01L 21/0254 (20130101)
H01L 21/0262 (20130101)
H01L 21/02293 (20130101)
H01L 21/02387 (20130101)
H01L 21/02389 (20130101)
H01L 21/02392 (20130101)
H01L 21/02395 (20130101)
H01L 21/02398 (20130101)
H01L 21/02458 (20130101)
H01L 21/02461 (20130101)
H01L 21/02463 (20130101)
H01L 21/02466 (20130101)
H01L 21/02505 (20130101)
H01L 21/02538 (20130101)
H01L 21/02543 (20130101)
H01L 21/02546 (20130101)
H01L 21/02549 (20130101)
H01L 21/02551 (20130101)
H01L 21/02568 (20130101)
H01L 21/02658 (20130101)
H01L 31/1828 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795575 Tassev
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Vladimir Tassev (Beavercreek, Ohio)
ABSTRACT A method of performing HVPE heteroepitaxy comprises exposing a substrate to a carrier gas, a first precursor gas, a Group II/III element, and ternary-forming gasses (V/VI group precursor), to form a heteroepitaxial growth of a binary, ternary, and/or quaternary compound on the substrate; wherein the carrier gas is Hz, wherein the first precursor gas is HCl, the Group II/III element comprises at least one of Zn, Cd, Hg, Al, Ga, and In; and wherein the ternary-forming gasses comprise at least two or more of AsH3 (arsine), PH3 (phosphine), H2Se (hydrogen selenide), HzTe (hydrogen telluride), SbH3 (hydrogen antimonide, or antimony tri-hydride, or stibine), H2S (hydrogen sulfide), NH3 (ammonia), and HF (hydrogen fluoride); flowing the carrier gas over the Group II/III element; exposing the substrate to the ternary-forming gasses in a predetermined ratio of first ternary-forming gas to second ternary-forming gas (1tf:2tf ratio); and changing the 1tf:2tf ratio over time.
FILED Monday, October 17, 2022
APPL NO 18/046946
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/02 (20130101)
C30B 25/04 (20130101) Original (OR) Class
C30B 25/18 (20130101)
C30B 29/42 (20130101)
C30B 29/44 (20130101)
C30B 29/48 (20130101)
C30B 29/403 (20130101)
C30B 29/406 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3556 (20130101)
G02F 1/3558 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/024 (20130101)
H01L 21/0254 (20130101)
H01L 21/0262 (20130101)
H01L 21/02293 (20130101)
H01L 21/02387 (20130101)
H01L 21/02389 (20130101)
H01L 21/02392 (20130101)
H01L 21/02395 (20130101)
H01L 21/02398 (20130101)
H01L 21/02458 (20130101)
H01L 21/02461 (20130101)
H01L 21/02463 (20130101)
H01L 21/02466 (20130101)
H01L 21/02505 (20130101)
H01L 21/02538 (20130101)
H01L 21/02543 (20130101)
H01L 21/02546 (20130101)
H01L 21/02549 (20130101)
H01L 21/02551 (20130101)
H01L 21/02568 (20130101)
H01L 21/02658 (20130101)
H01L 31/1828 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795900 Filardo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Pliant Energy Systems LLC (Brooklyn, New York)
ASSIGNEE(S) Pliant Energy Systems LLC (Brooklyn, New York)
INVENTOR(S) Benjamin Pietro Filardo (New York, New York);  Daniel S. Zimmerman (Brooklyn, New York);  Michael I. Weaker (Brooklyn, New York)
ABSTRACT The VEHICLE WITH TRAVELING WAVE THRUST MODULE APPARATUSES, METHODS AND SYSTEMS include force or forces applied to an arc-like flexible sheet-like material to create a deformed crenated strip fin with strained-deformations. The strained-deformations take on a sinusoid-like form that express the internal energy state of the flexible sheet-like material after it has been configured into a crenated strip fin. After being incorporated into a mechanism with couplings that prevent the crenated strip fin from returning to its un-strained state, the strained-deformations persist. Actuators may be used to sequentially rotate vertebrae attached to the fins causing the travel of sinusoid-like deformations along the fins. The fin, fin actuator or actuators, power source and central controller may be incorporated into a thrust module. Two thrust modules coupled to a central body via roll actuators and flexible coupling members may form a vehicle with exceptional maneuverability.
FILED Thursday, November 18, 2021
APPL NO 17/530190
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 35/00 (20130101)

Vehicles for Use Both on Rail and on Road; Amphibious or Like Vehicles; Convertible Vehicles
B60F 3/0007 (20130101)

Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 50/60 (20190201)

Motor Vehicles; Trailers
B62D 57/02 (20130101)

Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 8/08 (20130101)

Lighter-than Air Aircraft
B64B 1/00 (20130101)

Machines or Engines for Liquids
F03B 13/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796268 Hoffman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Brian R Hoffman (Bloomington, Indiana);  Caleb W McGee (Bloomington, Indiana);  John David Lawrence (Bloomington, Indiana);  Calvin Tyler Lawson (Springville, Indiana)
ABSTRACT Provided is a firearm cartridge chamber with a relief feature that traps a portion of a cartridge case within the cartridge chamber when fired. The relief feature causes the cartridge case to deform within the chamber, wherein it optionally separates into a forward section and a rearward section. The deformed case remains trapped after firing, preventing extraction of the fired case and the chambering or firing of any subsequent cartridges, thereby causing a firearm malfunction. The cartridge chamber can distinguish between higher and lower pressure cartridges by allowing for normal firing and function with blank training ammunition while also facilitating localized deformation of the cartridge case when firing standard ammunition that includes one or more projectiles. The inventive chamber prevents more than one higher pressure round from firing while allowing lower pressure or training rounds to fire without limitation, which aids in enhanced safety during training exercises.
FILED Wednesday, July 14, 2021
APPL NO 17/375072
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 17/34 (20130101) Original (OR) Class
F41A 21/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796279 Vabnick et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland)
ASSIGNEE(S) The United States of America, as represented by the secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Ian B. Vabnick (Fredericksburg, Virginia);  Phillip R. Quillen (Redstone Arsenal, Alabama);  Eric S. Morefield (Quantico, Virginia);  Arthur W. Ellis (Swan Point, Maryland);  Lee Foltz (Indian Head, Maryland)
ABSTRACT Provided herein are projectiles for use in a propellant driven disrupter device, and associated methods, to neutralize an explosive target. The projectile may comprise a friction reducing container at least partially filled with one or more fluids, fluid mixtures, particles, and other components to provide one or more desired fluid properties to achieve a desired one or more jet parameters upon target impact. The fluid(s) in the container are referred to as highly efficient energy transfer (HEET) fluids do to the improved fluid jet action on target compared to conventional water projectiles. The projectiles and disruptor can be more precisely individually tailored to the target, thereby increasing the likelihood of successful disablement and decreasing the likelihood of inadvertent and uncontrolled explosion.
FILED Wednesday, September 29, 2021
APPL NO 17/300686
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for
F41B 9/0046 (20130101) Original (OR) Class

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 33/062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796419 Redding et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Brandon F. Redding (University Park, Maryland);  Joseph B. Murray (Ellicott City, Maryland)
ABSTRACT Brillouin fiber sensors can provide distributed measurements of parameters of interest over long distances in a fiber by measuring the Brillouin frequency shift as a function of position along the fiber. The Brillouin frequency shift may be determined, to within a small fraction of the Brillouin linewidth, by establishing a series of lasing modes that experience Brillouin amplification at discrete spatial locations in a test fiber. A linewidth narrowing and high intensity associated with the lasing transition enable precise measurements of the lasing frequency associated with each of the lasing modes. The Brillouin frequency may be determined based on the lasing frequency.
FILED Wednesday, August 11, 2021
APPL NO 17/400107
ART UNIT 2877 — Optics
CURRENT CPC
Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 11/3109 (20130101) Original (OR) Class

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/302 (20130101)
H01S 3/08036 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796511 Ruffa
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (, None)
INVENTOR(S) Anthony A Ruffa (Hope Valley, Rhode Island)
ABSTRACT A system and method for monitoring structural health of a beam using at least one pair of data collection devices mounted along the beam at a spacing distance to define a measurement region. A computer-implemented drive system in communication with the accelerator pairs executes instructions to monitor each measurement regions for propagating transverse waves. After initialization of a propagation speed threshold for each measurement region, a continuous and real-time monitoring loop operates the accelerometers to detect propagations of a transverse wave along the measurement region. For each propagation event, a time delay is determined and, in turn, a propagation speed for the transverse wave based on the time delay and known spacing distance of the measurement region. If the propagation speed violates the threshold set for the measurement region, an alert condition for beam damage is reported and if the propagation speed satisfies the threshold, a success condition is reported.
FILED Wednesday, April 20, 2022
APPL NO 17/724527
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/07 (20130101) Original (OR) Class
G01N 29/045 (20130101)
G01N 29/449 (20130101)
G01N 29/4427 (20130101)
G01N 2291/105 (20130101)
G01N 2291/0289 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796562 Waite et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Nanotok LLC (Eastsound, Washington);  University of Washington (Seattle, Washington)
ASSIGNEE(S) AIVS Inc. (Seattle, Washington)
INVENTOR(S) James W. Waite (Eastsound, Washington);  David Raymond Dall'Osto (Seattle, Washington);  Peter Hans Dahl (Seattle, Washington)
ABSTRACT An airborne acoustic vector sensor for simultaneously measuring triaxial particle acceleration in three dimensions and pressure includes a triaxial MEMS accelerometer sensitive to an Earth gravitational field. The airborne acoustic vector sensor includes one or multiple MEMS microphones sensitive to sound pressure and overlapping the accelerometer in frequency. The airborne acoustic vector sensor includes a solid body having a density approximating a density of air. The accelerometer is mounted in or upon the solid body. The airborne acoustic vector sensor includes a suspension system supporting the accelerometer and solid body within a framework.
FILED Thursday, May 27, 2021
APPL NO 17/332390
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 2201/0235 (20130101)
B81B 2201/0257 (20130101)

Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 3/125 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 15/18 (20130101) Original (OR) Class

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 3/803 (20130101)
G01S 5/08 (20130101)

Holographic Processes or Apparatus
G03H 3/00 (20130101)

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/004 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 29/005 (20130101)
H04R 2201/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796664 Ewing et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) US Gov't as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Robert Ewing (Kettering, Ohio);  Yuan Zheng (Columbus, Ohio);  Siyang Cao (Tucson, Arizona);  David Brendel (Dayton, Ohio)
ABSTRACT The present disclosure addresses a novel feedback design methodology to meet the emerging frontiers of beamforming radio frequency (RF) technology in the areas of machine learning and surveillance. The feasibility of developing adaptive waveform modulation schemes for spectrum management in radars via orthogonal wavelet concepts. With the increasing prevalence of RF spectrum bandwidth limitations, this approach of adaptive feedback waveforms addresses advanced signal processing beamforming technique for phase array RF improving overall sensing performance. The adaptive illumination waveform algorithms for enhancing detection, discrimination, and tracking is motivated from the analogy drawn between the cellular wireless communication systems and the general multi-static radar automotive systems. The present innovation has developed signal processing schemes of adaptive illumination waveforms for enhancing RF detection performance and have developed a unified system architecture of the adaptive radar waveform design for various scenarios including multi-static radars and multiple targets.
FILED Wednesday, December 30, 2020
APPL NO 17/137478
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/2813 (20130101)
G01S 13/426 (20130101) Original (OR) Class
G01S 2013/0245 (20130101)

Antennas, i.e Radio Aerials
H01Q 3/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796746 Galvan
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jaime Galvan (Bloomington, Indiana)
ABSTRACT Provided is a secure quick communication system disconnect switch box that enables remote verification of communication path connection or disconnection status. The box utilizes a lid having an affixed jumper circuit/assembly bridging or coupling at least two network connections. When the lid to the switch box is attached, the at least two computers/networks are connected via the jumper circuit/assembly. When the lid is removed from the switch box, the jumper circuit/assembly is disconnected from the at least two computer/networks, thereby disconnecting and isolating the otherwise coupled computers/networks. Removal of the lid additionally exposes network maintenance/access ports to provide access to one or more of the computers/network. When the lid is closed, the network maintenance/access ports are inaccessible to the user.
FILED Tuesday, May 17, 2022
APPL NO 17/746222
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/3834 (20130101)
G02B 6/3897 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796798 Gopinath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Juliet Gopinath (Boulder, Colorado);  Mo Zohrabi (Boulder, Colorado);  Victor M. Bright (Boulder, Colorado);  Omkar Supekar (Boulder, Colorado);  Robert H. Cormack (Erie, Colorado);  Emily Gibson (Boulder, Colorado);  Connor McCullough (Denver, Colorado)
ABSTRACT The present disclosure relates generally to methods and systems useful in imaging applications, especially biological imaging applications, and applications in the metrology, atmospheric, scientific and medical fields. In one aspect, the disclosure provides a method of imaging an object, including illuminating the object with incident radiation through one or more adaptive optical elements; receiving transmitted radiation from the object at a photodetector to provide a base image; and performing the following steps one or more times: adjusting the one or more adaptive optical elements, the adjustment including modifying an optical transfer function of the one or more adaptive optical elements, and receiving transmitted radiation from the object at the photodetector to provide an adjusted image; wherein the adjustment and receiving steps are performed until the adjusted image has substantially reduced aberrations compared to the base image.
FILED Wednesday, October 03, 2018
APPL NO 16/753615
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101)
G02B 27/0068 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797842 Chu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Linsong Chu (White Plains, New York);  Pranita Sharad Dewan (White Plains, New York);  Raghu Kiran Ganti (Elmsford, New York);  Joshua M. Rosenkranz (Westchester, New York);  Mudhakar Srivatsa (White Plains, New York)
ABSTRACT Aspects of the present disclosure relate to identifying friction points in customer data. In some embodiments, identifying friction points can include receiving a set of input sequence data and predicted class labels for the set of input sequence data; selecting input sequences, from the set of input sequence data, that have class labels matching a ground truth class label; reducing the selected sequences to anchor points; and grouping the reduced selected sequences into critical data set signatures using discriminatory subsequence mining.
FILED Friday, August 02, 2019
APPL NO 16/530020
ART UNIT 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Electric Digital Data Processing
G06F 16/285 (20190101)
G06F 16/2465 (20190101)
G06F 2216/03 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797894 Ezick et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Space and Missile Defense Command (SMDC)
U.S. Army Space and Missile Defense Command (USASMDC)
APPLICANT(S) QUALCOMM TECHNOLOGIES, INC (San Diego, California)
ASSIGNEE(S) QUALCOMM Incorporated (San Diego, California)
INVENTOR(S) James Ezick (Canonsburg, Pennsylvania);  Jonathan Springer (Carbondale, Illinois);  Nicolas T. Vasilache (New York, New York)
ABSTRACT In a system for enabling configuration of an ensemble of several solvers, such that the ensemble can efficiently solve a constraint problem, for each one of several candidate configurations, an array of scores is computed. The array corresponds to a statistical parameter related to a problem solution, and the computation is based on, at least in part, a set of features associated with the problem. One candidate configuration is assigned to a solver, and based on the array of scores associated with that candidate configuration the same or a different candidate configuration is assigned to a another solver. A system for dynamically reconfiguring an ensemble of solvers obtains runtime data from several solvers, and a new configuration is determined by applying a machine learning and/or heuristic analysis procedure to the runtime data. The configuration of a solver may be updated according to the new configuration while that solver is running.
FILED Monday, November 16, 2020
APPL NO 17/098916
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/01 (20230101)
G06N 5/02 (20130101)
G06N 20/00 (20190101)
G06N 20/20 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798127 Bruder et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Gerd Bruder (Orlando, Florida);  Gregory Welch (Orlando, Florida);  Kangsoo Kim (Orlando, Florida);  Zubin Choudhary (Orlando, Florida)
ABSTRACT One or more cameras capture objects at a higher resolution than the human eye can perceive. Objects are segmented from the background of the image and scaled to human perceptible size. The scaled-up objects are superimposed over the unscaled background. This is presented to a user via a display whereby the process selectively amplifies the size of the objects' spatially registered retinal projection while maintaining a natural (unmodified) view in the remainder of the visual field.
FILED Wednesday, June 29, 2022
APPL NO 17/853072
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Image Data Processing or Generation, in General
G06T 3/40 (20130101) Original (OR) Class
G06T 7/73 (20170101)
G06T 7/194 (20170101)
G06T 19/006 (20130101)

Image or Video Recognition or Understanding
G06V 10/764 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798129 Rehling
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) John F. Rehling (Encinitas, California)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) John F. Rehling (Encinitas, California)
ABSTRACT In the described examples, a compiled image scaler includes a set of machine executable instructions that generate a scaled image that is a scaled version of a source image with integer and bitwise operations. The compiled image scaler employs filtering to blend colors of adjacent pixels in the source image to generate the scaled image, and each filtering operation concurrently scales three color channels of a pixel in the source image.
FILED Friday, December 17, 2021
APPL NO 17/553885
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 1/20 (20130101)
G06T 3/4023 (20130101) Original (OR) Class
G06T 5/002 (20130101)
G06T 5/20 (20130101)
G06T 7/90 (20170101)
G06T 2207/10024 (20130101)
G06T 2207/20192 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798179 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Eye Institute (NEI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Jacob Antunes (Cincinnati, Ohio);  Zhouping Wei (Cleveland, Ohio);  Pallavi Tiwari (Wexford, Pennsylvania);  Satish E. Viswanath (Pepper Pike, Ohio);  Charlems Alvarez Jimenez (Bogotá, Colombia)
ABSTRACT The present disclosure, in some embodiments, relates to a non-transitory computer-readable medium storing computer-executable instructions. The computer readable medium is configured to cause a processor to access an image volume of a rectum comprising a rectal tumor. A forward mapping is generated based on non-rigidly registering a healthy rectal atlas to the image volume. The forward mapping is inverted to generate an inverse mapping from the image volume to the healthy rectal atlas. Based on the inverse mapping, a plurality of deformation vectors, associated with a deformation within a rectal wall of the rectum, are determined. Magnitude based deformation features and orientation based deformation features are computed from the plurality of deformation vectors. One or more of the magnitude based deformation features and one or more of the orientation based deformation features are utilized to determine a response of a patient to a chemoradiation treatment.
FILED Wednesday, September 22, 2021
APPL NO 17/481625
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/33 (20170101) Original (OR) Class
G06T 7/38 (20170101)
G06T 2207/10088 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
G16H 50/70 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798254 Banerjee et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Srutarshi Banerjee (Chicago, Illinois);  Henry H. Chopp (Glencoe, Illinois);  Juan Gabriel Serra Pérez (Evanston, Illinois);  Zihao Wang (Evanston, Illinois);  Oliver Strider Cossairt (Evanston, Illinois);  Aggelos K. Katsaggelos (Chicago, Illinois)
ABSTRACT A system to process imaging data includes an imaging system configured to capture image data and event data of a scene, compress the image data and the event data, and transmit the compressed image data and compressed event data to a host. The host is operatively coupled to the imaging system, and includes a processor configured to perform object detection on the compressed image data and the compressed event data to identify one or more objects. The processor is also configured to perform object tracking on the one or more objects. The processor is also configured to predict one or more regions of interest for subsequent data capture based on the object detection and the object tracking. The processor is further configured to provide the one or more regions of interest to the imaging system to control capture of additional image data and additional event data by the imaging system.
FILED Tuesday, August 31, 2021
APPL NO 17/462423
ART UNIT RD00 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/277 (20170101)
G06T 2207/20084 (20130101)
G06T 2207/20192 (20130101)
G06T 2207/30232 (20130101)

Image or Video Recognition or Understanding
G06V 10/25 (20220101) Original (OR) Class
G06V 20/52 (20220101)

Pictorial Communication, e.g Television
H04N 7/183 (20130101)
H04N 7/188 (20130101)
H04N 19/46 (20141101)
H04N 19/96 (20141101)
H04N 19/132 (20141101)
H04N 19/147 (20141101)
H04N 19/167 (20141101)
H04N 19/176 (20141101)
H04N 23/61 (20230101)
H04N 23/64 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799260 Bukowski
FUNDED BY
Department of Defense (DOD)
Office of the Secretary of Defense (OSD)
DOD Ordnance Technology Consortium (DOTC)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Leva E. Bukowski (Plano, Texas)
ABSTRACT An apparatus includes a diffractive grating configured to receive multiple output beams from an array of laser sources. The apparatus also includes one or more optical elements configured to receive, direct, and focus multiple zeroth-order light beams, where the zeroth-order light beams include portions of the output beams reflected off the diffractive grating. The apparatus further includes a detector configured to receive the zeroth-order light beams from at least one of the one or more optical elements and process the zeroth-order light beams to generate diagnostic information.
FILED Thursday, October 08, 2020
APPL NO 17/066320
ART UNIT 2878 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/4257 (20130101)

Optical Elements, Systems, or Apparatus
G02B 17/023 (20130101)
G02B 27/30 (20130101)
G02B 27/4233 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0014 (20130101) Original (OR) Class
H01S 3/067 (20130101)
H01S 3/2383 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799673 Ganji et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida);  TECHNISCHE UNIVERSITAET BERLIN (Berlin, Germany)
INVENTOR(S) Fatemeh Ganji (Gainesville, Florida);  Shahin Tajik (Gainesville, Florida);  Jean-Pierre Seifert (Werder Havel, Germany);  Domenic Forte (Gainesville, Florida);  Mark M. Tehranipoor (Gainesville, Florida)
ABSTRACT Combined physical unclonable function (PUFs); methods, apparatuses, systems, and computer program products for enrolling combined PUFs; and methods, apparatuses, systems, and computer program products for authenticating a device physically associated with a combined PUF are described. In an example embodiment, a combined PUF includes a plurality of PUFs and one or more logic gates. Each PUF includes a plurality of stages and an arbiter configured to generate a single PUF response based on response portions generated by the plurality of stages. The one or more logic gates are configured to combine the single PUF response for each of the plurality of PUFs in accordance with a combination function to provide a combined response.
FILED Tuesday, April 07, 2020
APPL NO 16/841873
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 19/0963 (20130101)
H03K 19/1737 (20130101)
H03K 19/17748 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/002 (20130101)
H04L 9/0866 (20130101)
H04L 9/3271 (20130101)
H04L 9/3278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799674 Cambou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNVERSITY (Flagstaff, Arizona)
INVENTOR(S) Bertrand F Cambou (Flagstaff, Arizona);  Fatemeh Afghah (Flagstaff, Arizona);  Sareh Assiri (Flagstaff, Arizona);  Ashwija Korenda (Flagstaff, Arizona)
ABSTRACT Systems and methods of correcting errors in encrypted communication between a server and client devices using keyless encryption schemes are disclosed. Client devices with arrays of physical-unclonable-function devices respond to challenges from a server. Characteristics of the arrays are stored by the server during a secure enrollment process. To send an encrypted message, the server generates a message digest, extracts data from the stored arrays on the basis of the message digest, applies error correction codes to the message, encrypts the message with the extracted data, and sends the message to a client. The server may receive a handshake containing all or part of the message digest, measures its PUF, and decrypts and decodes the message.
FILED Friday, December 03, 2021
APPL NO 17/542118
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0869 (20130101)
H04L 9/3242 (20130101)
H04L 9/3278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799799 Blumrich et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) NVIDIA Corp. (Santa Clara, California)
ASSIGNEE(S) NVIDIA Corp. (Santa Clara, California)
INVENTOR(S) Matthias Augustin Blumrich (Ridgefield, Connecticut);  Nan Jiang (Acton, Massachusetts);  Larry Robert Dennison (Mendon, Massachusetts)
ABSTRACT A switch architecture enables ports to stash packets in unused buffers on other ports, exploiting excess internal bandwidth that may exist, for example, in a tiled switch. This architecture leverages unused port buffer memory to improve features such as congestion handling and error recovery.
FILED Friday, July 16, 2021
APPL NO 17/377943
ART UNIT 2419 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 49/70 (20130101)
H04L 49/101 (20130101) Original (OR) Class
H04L 49/254 (20130101)
H04L 49/3036 (20130101)
H04L 49/9047 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11800051 Gooden
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Dominic R. Gooden (El Segundo, California)
ABSTRACT A calibration disc for providing uniform irradiance to an optical sensor system includes a first major surface, a second major surface opposite the first major surface, and an edge surface extending around a circumference of the calibration disc. The first major surface is fully reflective and partially diffuse, the second major surface is partially reflective and partially diffuse, and the edge surface is fully reflective and partially diffuse and has an entrance aperture positioned at the edge surface and configured to receive light into the calibration disc. The first major surface, the second major surface and the edge surface are configured to scatter the light received by the entrance aperture within the calibration disc. The second major surface is configured to emit at least some of the light with uniform irradiance.
FILED Friday, December 17, 2021
APPL NO 17/554785
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/274 (20130101)

Pictorial Communication, e.g Television
H04N 5/33 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11800205 Koppal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
INVENTOR(S) Sanjeev Jagannatha Koppal (Gainesville, Florida);  Zaid Tasneem (Gainesville, Florida);  Dingkang Wang (Gainesville, Florida);  Huikai Xie (Gainesville, Florida);  Brevin Jeffery Tilmon (Gainesville, Florida)
ABSTRACT Provided is a camera system to obtain high resolution imagery on multiple regions of interest even when the regions of interest are ate different focal depths and in different viewing directions. Embodiments include a high speed camera that operates by reflecting a beam of interest corresponding to a scene of interest into a high-speed passive sensor from a dynamic optical modulator. Embodiments described herein provide a foveating camera design that distributes resolution onto regions of interest by imaging reflections off a scanning micro-electromechanical system (MEMS) mirror. MEMS mirrors are used herein to modulate viewing direction. Embodiments include a camera capturing reflections off of a tiny, fast moving mirror.
FILED Thursday, April 09, 2020
APPL NO 16/844597
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 26/0841 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 39/04 (20130101)

Image Data Processing or Generation, in General
G06T 5/003 (20130101)
G06T 7/80 (20170101)

Pictorial Communication, e.g Television
H04N 23/45 (20230101) Original (OR) Class
H04N 23/55 (20230101)
H04N 23/66 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11800645 Petelik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Thomas Petelik (Alexandria, Virginia);  Steven Bode (Alexandria, Virginia);  Matthew Anderson (Hanover, Maryland)
ABSTRACT An apparatus for interfacing with an RF/microwave subsystem is provided. The apparatus includes a printed circuit board that includes: a controller, and a connector constructed to provide control signals and power signals to a subsystem in accordance with instructions from the controller, and a mechanical interface constructed to provide a mechanical connection between the subsystem and the printed circuit board.
FILED Tuesday, August 02, 2022
APPL NO 17/879484
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 12/716 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/181 (20130101) Original (OR) Class
H05K 2201/10189 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11800784 Dou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Letian Dou (West Lafayette, Indiana);  Yao Gao (West Lafayette, Indiana);  Enzheng Shi (West Lafayette, Indiana)
ABSTRACT The present disclosure relates to novel two-dimensional halide perovskite materials, and the method of making and using the two-dimensional halide perovskite materials.
FILED Friday, September 04, 2020
APPL NO 17/012137
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/24 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 2211/188 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 9/20 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/36 (20130101)

Organic electric solid-state devices
H10K 85/30 (20230201) Original (OR) Class

Electric solid-state devices not otherwise provided for
H10N 10/856 (20230201)
H10N 10/857 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11793165 Deng et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Z. Daniel Deng (Richland, Washington);  Huidong Li (Richland, Washington);  Mitchell J. Myjak (Richland, Washington);  Jun Lu (Richland, Washington);  Jayson J. Martinez (Kennewick, Washington);  Jiguang Zhang (Richland, Washington);  Samuel S. Cartmell (Richland, Washington);  Yuxing Wang (Richland, Washington);  Qiuyan Li (Richland, Washington);  Jie Xiao (Richland, Washington)
ABSTRACT Systems and methods for monitoring organisms within an aquatic environment are described. According to one aspect, an injectable acoustic transmission device includes a body configured to be injected inside of an organism, a transducer within the body and configured to convert a plurality of electrical signals into a plurality of data transmissions which are transmitted externally of the body and the organism, a plurality of circuit components within the body and configured to use electrical energy from a power source to generate the electrical signals which are provided to the transducer, and wherein the transducer defines an internal volume and at least one of the circuit components is provided within the internal volume of the transducer.
FILED Tuesday, December 24, 2019
APPL NO 16/726574
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 11/006 (20130101) Original (OR) Class
A01K 61/95 (20170101)

Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/0655 (20130101)

Transmission
H04B 1/385 (20130101)
H04B 11/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794406 Moran et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Bryan D. Moran (Pleasanton, California);  Elaine Lee (Moraga, California);  Caitlyn Christian Krikorian (Livermore, California);  Logan Bekker (Pleasanton, California)
ABSTRACT A method of forming a three-dimensional structure of liquid crystal (LC) elastomers includes contacting a resin layer of LC oligomers with a layer of photoalignment material, and exposing a portion of photoalignment material to light for aligning the portion of photoalignment material in a first orientation. The LC oligomers adjacent the illuminated portion of photoalignment material align to the first orientation of the illuminated portion. The portion of aligned LC oligomers of the resin layer are cured. Operations for forming additional layers include creating a relative movement of the resin layer away from the photoalignment material, contacting another resin layer with the photoalignment material, and exposing another portion of photoalignment material to light for aligning the photoalignment material in a different orientation. The LC oligomers adjacent the illuminated portion of photoalignment material align to the different orientation, and the portion of aligned LC oligomers of the resin layer are cured.
FILED Thursday, June 23, 2022
APPL NO 17/848309
ART UNIT 1782 — Miscellaneous Articles, Stock Material
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/129 (20170801) Original (OR) Class

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2105/0079 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794415 Kim et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Seokpum Kim (Knoxville, Tennessee);  Ahmed A. Hassen (Knoxville, Tennessee);  John M. Lindahl (Knoxville, Tennessee);  Lonnie J. Love (Knoxville, Tennessee);  Vlastimil Kunc (Knoxville, Tennessee);  Thomas Feldhausen (Knoxville, Tennessee)
ABSTRACT A simulation-assisted additive manufacturing system and method for generating an anisotropic compensation to account for non-uniform deformation due to additive manufacturing and service loading. The predicted deformation may not be fully defined. The present disclosure provides a system and method for estimating the missing deformation data through regression analysis. The present disclosure also provides an integrated framework where the various simulated-assisted design modules are configured for two-way communication and sharing access to changes to the model.
FILED Wednesday, September 15, 2021
APPL NO 17/475512
ART UNIT 2116 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/386 (20170801)
B29C 64/393 (20170801) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 50/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794717 Le et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Cummins Inc. (Columbus, Indiana)
ASSIGNEE(S) CUMMINS INC. (Columbus, Indiana)
INVENTOR(S) Dat Duc Le (Columbus, Indiana);  Carlos A. Lana (Columbus, Indiana);  Kenneth M. Follen (Greenwood, Indiana)
ABSTRACT A system and method for power management of hybrid electric vehicles is provided. In some implementations, a plug-in series hybrid electric vehicle may include an engine, a motor/generator (MG), a traction motor, an energy storage device, and a controller. The controller is coupled to the engine and the MG to control operation of the engine and the MG such that a state-of-charge (SOC) of the energy storage device tracks a dynamic reference SOC profile during a trip and an average engine power (AEP) is maintained above a threshold. In some instances, maintaining AEP above a threshold supports emission control of the vehicle.
FILED Sunday, May 02, 2021
APPL NO 17/246678
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 6/24 (20130101)
B60K 6/26 (20130101)
B60K 6/28 (20130101)
B60K 6/46 (20130101)

Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 10/06 (20130101)
B60W 10/08 (20130101)
B60W 20/11 (20160101)
B60W 20/12 (20160101)
B60W 20/13 (20160101) Original (OR) Class
B60W 2510/068 (20130101)
B60W 2510/244 (20130101)
B60W 2510/0619 (20130101)
B60W 2510/0666 (20130101)
B60W 2510/0676 (20130101)
B60W 2520/10 (20130101)
B60W 2530/209 (20200201)
B60W 2540/10 (20130101)
B60W 2555/20 (20200201)
B60W 2710/06 (20130101)
B60W 2710/08 (20130101)

Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology
B60Y 2200/92 (20130101)
B60Y 2300/91 (20130101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795070 Lin
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) West Virginia University Board of Governors on behalf of West Virginia University (Morgantown, West Virginia)
ASSIGNEE(S) West Virginia University Board of Governors on behalf of West Virginia University (Morgantown, West Virginia)
INVENTOR(S) Lian-Shin Lin (Morgantown, West Virginia)
ABSTRACT This invention provides processes for treating a mixture of produced water and blowdown water comprising introducing produced water (PW) into blowdown water (BD) for forming a PW-BD water mixture, softening the PW-BD water mixture, subjecting the PW-BD water mixture to activated carbon filtration and reverse osmosis membrane desalination. The process generates a product water and a brine by-product.
FILED Friday, September 17, 2021
APPL NO 17/448004
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/001 (20130101)
C02F 1/441 (20130101) Original (OR) Class
C02F 1/4618 (20130101)
C02F 5/02 (20130101)
C02F 9/00 (20130101)
C02F 2001/4619 (20130101)
C02F 2101/20 (20130101)
C02F 2103/34 (20130101)
C02F 2303/20 (20130101)
C02F 2303/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795122 Aguirrezabal et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) Research Triangle Institute (Research Triangle Park, North Carolina);  University of the Basque Country (Lejona, Spain)
ASSIGNEE(S) RESEARCH TRIANGLE INSTITUTE (Research Triangle Park, North Carolina);  UNIVERSITY OF THE BASQUE COUNTRY (Lejona, Spain)
INVENTOR(S) Iker Aguirrezabal (Research Triangle Park, North Carolina);  Ignacio Luz Minguez (Research Triangle Park, North Carolina);  Mustapha Soukri (Research Triangle Park, North Carolina);  Marty Lail (Research Triangle Park, North Carolina);  Pedro Luis Arias (Research Triangle Park, North Carolina)
ABSTRACT Described herein is a catalytic reaction process including introducing one or more gas-phase reactants into a reactor comprising a microporous catalyst having a pore size less than or equal to 2 nm and adjusting the temperature and/or the pressure of the reactor such that one or more of the gas-phase reactants condense within the micropores of the catalyst thereby causing the catalytic reaction to take place in a liquid phase. Additionally, a process for engineering defects on a carboxylate-based metal organic framework (MOF) catalyst is described. The process includes providing a carboxylate-based MOF catalyst; and heating the carboxylate-based MOF catalyst in an inert gas atmosphere at temperatures between about 150° C. and about 900° C.
FILED Wednesday, July 17, 2019
APPL NO 17/262490
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/1691 (20130101)
B01J 35/1057 (20130101)
B01J 2231/12 (20130101)
B01J 2531/821 (20130101)

Acyclic or Carbocyclic Compounds
C07C 2/32 (20130101) Original (OR) Class
C07C 2523/46 (20130101)
C07C 2531/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795388 Myllenbeck et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Nicholas Myllenbeck (Livermore, California);  Patrick L. Feng (Livermore, California);  Joseph Carlson (Castro Valley, California)
ABSTRACT A plastic scintillator includes a polymeric matrix comprising a primary fluorophore capable of forming an amorphous glass in its pure form. The primary fluorophore is also capable of generating luminescence in the presence of ionizing radiation and includes: a central species including silicon; a luminescent organic group bonded to the central species or to an optional organic linker group, the luminescent organic group including fluorene or an analog thereof; and the optional organic linker group, if present, is bonded to the central species and the luminescent organic group.
FILED Friday, August 05, 2022
APPL NO 17/881859
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101) Original (OR) Class
C09K 11/025 (20130101)
C09K 2211/1011 (20130101)
C09K 2211/1014 (20130101)
C09K 2211/1018 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/2033 (20130101)
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US 11795403 Singh et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Vijay Singh (Savoy, Illinois);  Ramkrishna Singh (Urbana, Illinois)
ABSTRACT The disclosure provides various methods for separating and recovering free fatty acids crude oil containing free fatty acids using certain ion-exchange resins to reduce the amount of free fatty acids in the crude oil to 3% or less such that the resultant oil is useable in downstream chemical processes. After separation and removal of the free fatty acids form the crude oil, the ion-exchange resin is reusable in further free fatty acid separation reactions.
FILED Tuesday, May 31, 2022
APPL NO 17/828955
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 25/02 (20130101) Original (OR) Class
C10G 25/006 (20130101)
C10G 25/12 (20130101)
C10G 2300/201 (20130101)
C10G 2300/1007 (20130101)
C10G 2300/4081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795472 Doudna et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A. Doudna (Berkeley, California);  Jillian Banfield (Berkeley, California);  David Burstein (Berkeley, California);  Lucas Benjamin Harrington (Berkeley, California);  Steven C. Strutt (Berkeley, California)
ABSTRACT The present disclosure provides CasX proteins, nucleic acids encoding the CasX proteins, and modified host cells comprising the CasX proteins and/or nucleic acids encoding same. CasX proteins are useful in a variety of applications, which are provided. The present disclosure provides CasX guide RNAs that bind to and provide sequence specificity to the CasX proteins, nucleic acids encoding the CasX guide RNAs, and modified host cells comprising the CasX guide RNAs and/or nucleic acids encoding same. CasX guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides archaeal Cas9 polypeptides and nucleic acids encoding same, as well as their associated archaeal Cas9 guide RNAs and nucleic acids encoding same.
FILED Friday, May 24, 2019
APPL NO 16/422824
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 19/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/06 (20130101)
C07K 2319/09 (20130101)
C07K 2319/20 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/1007 (20130101)
C12N 9/1025 (20130101)
C12N 15/52 (20130101)
C12N 15/62 (20130101)
C12N 15/74 (20130101)
C12N 15/85 (20130101)
C12N 15/86 (20130101)
C12N 15/88 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101)
C12N 15/902 (20130101)
C12N 15/8509 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2740/13043 (20130101)
C12N 2740/16043 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795567 Soares et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S) Brookhaven Science Associates, LLC (Upton, New York)
ASSIGNEE(S) Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S) Alexei S. Soares (Shirley, New York);  Karan Joshi (Eatontown, New Jersey);  Grace C. Shea-McCarthy (Shoreham, New York);  Lauren E. Zipper (Somerville, Massachusetts);  Ella Teplitsky (Suffern, New York)
ABSTRACT Technologies are described for methods and systems effective for flex plates. The flex plates may comprise a base plate. The base plate may include walls that define an insert location opening in the base plate. The insert location opening in the base plate may be in communication with a securement area. The flex plates may comprise an insert. The insert may include a reservoir region and a crystallization region separated by a wall including channels. The reservoir region and the crystallization region may include a backing. The insert may further include securement tabs. The securement tabs may be configured to secure the insert to the base plate at the securement area.
FILED Monday, November 30, 2020
APPL NO 17/107292
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)

Peptides
C07K 1/306 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 7/14 (20130101) Original (OR) Class
C30B 29/58 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2806 (20130101)
G01N 23/2076 (20130101)
G01N 2223/307 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795583 Dai et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Sheng Dai (Knoxville, Tennessee);  Huimin Luo (Knoxville, Tennessee);  Halie J. Martin (Huntsville, Alabama)
ABSTRACT A method for producing polyacrylonitrile (PAN) fiber, the method comprising: (i) mixing PAN with an ionic liquid in which the PAN is soluble to produce a PAN composite melt in which the PAN is dissolved in the ionic liquid; (ii) melt spinning the PAN composite melt to produce the PAN fiber; and (iii) washing the PAN fiber with a solvent in which the ionic liquid is soluble to substantially remove the ionic liquid from the PAN fiber. Also described herein is a method for producing carbon fiber from the PAN fiber as produced above, the method comprising oxidatively stabilizing the PAN fiber produced in step (iii), followed by carbonizing the stabilized PAN fiber to produce the carbon fiber. The initially produced PAN fiber, stabilized PAN fiber, resulting carbon fiber, and articles made thereof are also described.
FILED Friday, January 21, 2022
APPL NO 17/580851
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/10 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 6/54 (20130101) Original (OR) Class
D01F 9/225 (20130101)

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2321/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795904 Jenne et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Dale Scott Jenne (Arvada, Colorado);  Yi-Hsiang Yu (Golden, Colorado)
ABSTRACT Disclosed herein is a wave energy converter that uses a flexible and inflatable chamber to absorb wave energy and convert it to electrical energy through the varying hydrostatic and hydrodynamic pressure at or below the water surface.
FILED Monday, June 29, 2020
APPL NO 16/914982
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Machines or Engines for Liquids
F03B 13/148 (20130101)
F03B 13/188 (20130101) Original (OR) Class

Positive-displacement Machines for Liquids; Pumps
F04B 17/00 (20130101)
F04B 43/06 (20130101)
F04B 45/053 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796488 Avery et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Azure Dee Avery (Denver, Colorado);  Jeffrey Lee Blackburn (Golden, Colorado);  Andrew John Ferguson (Louisville, Colorado);  Taylor Christie Julia Aubry-Komin (Louisville, Colorado)
ABSTRACT Methods for determining desired doping conditions for a semiconducting single-walled carbon nanotube (s-SWCNT) are provided. One exemplary method includes doping each of a plurality of s-SWCNT networks under a respective set of doping conditions; determining a thermoelectric (TE) power factor as a function of a fractional bleach of an absorption spectrum for the plurality of s-SWCNT networks doped under the respective sets of doping conditions; and using the function to identify one of the TE power factors within a range of the fractional bleach of the absorption spectrum. The identified TE power factor corresponds to the desired doping conditions.
FILED Friday, January 15, 2021
APPL NO 17/150134
ART UNIT 1759 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/168 (20170801)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/62 (20130101)
G01N 23/20 (20130101) Original (OR) Class
G01N 2015/0038 (20130101)

Organic electric solid-state devices
H10K 71/30 (20230201)
H10K 85/221 (20230201)

Electric solid-state devices not otherwise provided for
H10N 10/855 (20230201)
H10N 19/00 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796490 Seidler et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
Office of Science (DOE-SC)
APPLICANT(S) UNIVERSITY OF WASHINGTON (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Gerald Todd Seidler (Seattle, Washington);  Oliver Hoidn (Seattle, Washington);  William Holden (Seattle, Washington)
ABSTRACT A spectrometer includes a crystal analyzer having a radius of curvature that defines a Rowland circle, a sample stage configured to support a sample such that the sample is offset from the Rowland circle, x-ray source configured to emit unfocused x-rays toward the sample stage, and a position-sensitive detector that is tangent to the Rowland circle. A method performed via a spectrometer includes emitting, via an x-ray source, unfocused x-rays toward a sample that is mounted on a sample stage such that the sample is offset from the Rowland Circle, thereby causing the sample to emit x-rays that impinge on the crystal analyzer or transmit a portion of the unfocused x-rays to impinge on the crystal analyzer; scattering, via the crystal analyzer, the x-rays that impinge on the crystal analyzer; and detecting the scattered x-rays via a position-sensitive detector that is tangent to the Rowland circle.
FILED Friday, July 02, 2021
APPL NO 17/366759
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/20 (20130101)
G01N 23/207 (20130101)
G01N 23/2076 (20130101) Original (OR) Class
G01N 23/20008 (20130101)
G01N 23/20025 (20130101)
G01N 23/20091 (20130101)
G01N 2223/32 (20130101)
G01N 2223/052 (20130101)
G01N 2223/307 (20130101)
G01N 2223/309 (20130101)
G01N 2223/5015 (20130101)
G01N 2291/045 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/2978 (20130101)
G01T 7/10 (20130101)

Optical Elements, Systems, or Apparatus
G02B 26/0816 (20130101)
G02B 27/0983 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 2201/062 (20130101)
G21K 2201/064 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796504 Ibrahim et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Yehia M. Ibrahim (West Richland, Washington);  Adam L. Hollerbach (Richland, Washington);  Ailin Li (Richland, Washington)
ABSTRACT An apparatus includes multiple levels of ion transport channels, with successive levels coupled by elevator channels. Efficient three dimensional packing provides long path lengths in practical volumes for ion mobility separation with high resolving power. Disclosed elevator configurations provide efficient routing of ion transport channels across levels with low ion loss, enabling ion mobility separation over 100 levels or more. Elevator configurations include (i) opposed traveling waves meeting at an elevator entrance, (ii) external elevator with a wrap-around electrode bank, (iii) external elevator with electrode banks on parallel extension plates, or (iv) elevator operating in surfing mode, in various combinations. Manufacture is aided by printed wiring boards, with interchangeable boards. Assembly with motherboard, spacer block(s), and alignment pins provides efficient distribution of electrode excitations and accurate reproducible positioning.
FILED Wednesday, August 11, 2021
APPL NO 17/399629
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/68 (20130101)
G01N 27/622 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 49/061 (20130101)
H01J 49/062 (20130101)
H01J 49/4225 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796508 Kunapuli et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Parker-Hannifin Corporation (Cleveland, Ohio)
ASSIGNEE(S) Parker-Hannifin Corporation (Cleveland, Ohio)
INVENTOR(S) Raghuit Prasad Kunapuli (Chesterfield, Missouri);  Praveen Thallapally (Richland, Washington);  Bernard P. McGrail (Pasco, Washington);  Deng Zhiqun (Richland, Washington);  Jian Liu (Richland, Washington);  Huidong Li (Richland, Washington);  Jun Lu (Richland, Washington);  Debasis Banerjee (Ellisville, Missouri)
ABSTRACT A SAW sensor is optimized for detection of refrigerant leakage in a refrigerant system or other gases, vapors, explosives or chemicals of interest. The SAW sensor includes a piezoelectric substrate; an interdigitated transducer deposited on the piezoelectric substrate, the interdigitated transducer having an input portion that receives input surface acoustic waves and an output portion that emits output surface acoustic waves; and a refrigerant sensor film located between the input portion and the output portion of the interdigitated transducer, the refrigerant sensor film including a sorbent material that is selected for preferential adsorption of a target refrigerant over atmospheric gases. Adsorption of the target refrigerant by the sorbent material results in a frequency shift of a frequency of the output surface acoustic waves relative to a frequency of the input surface acoustic waves. The sorbent material may be a metal organic framework (MOF) material, a covalent organic framework (COF) material, a porous organic cage or organic macrocyles such as calix [n] arene and its related derivatives.
FILED Tuesday, August 25, 2020
APPL NO 17/635118
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/022 (20130101) Original (OR) Class
G01N 2291/0256 (20130101)
G01N 2291/0423 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796533 Beer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) N. Reginald Beer (Pleasanton, California);  Steven W. Bond (Livermore, California)
ABSTRACT The disclosed technology includes a planar device for performing multiple biochemical assays at the same time, or nearly the same time. Each assay may include a biosample including a biochemical, enzyme, DNA, and/or any other biochemical or biological sample. Each assay may include one or more tags including dyes and/or other chemicals/reagents whose optical characteristics change based on chemical characteristics of the biological sample being tested. Each assay may be optically pumped to cause one or more of luminescence, phosphorescence, or fluorescence of the assay that may be detected by one or more optical detectors. For example, an assay may include two tags and a biosample. Each tag may be pumped by different wavelengths of light and may produce different wavelengths of light that is filtered and detected by one or more detectors. The pump wavelengths may be different from one another and different from the produced wavelengths.
FILED Wednesday, November 17, 2021
APPL NO 17/529249
ART UNIT 1796 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50 (20130101)
B01L 2300/0609 (20130101)
B01L 2300/0887 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6806 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101)
G01N 33/521 (20130101)
G01N 33/525 (20130101) Original (OR) Class
G01N 33/54366 (20130101)
G01N 2021/6419 (20130101)
G01N 2021/6421 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796612 Kehayias et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Pauli Mark Kehayias (Albuquerque, New Mexico);  Ezra Bussmann (Albuquerque, New Mexico);  Tzu-Ming Lu (Albuquerque, New Mexico);  Andrew Mounce (Albuquerque, New Mexico)
ABSTRACT A physically unclonable function (PUF) and a method of reading it are provided. The PUF is constituted by a microfabricated array of randomly polarized micromagnets disposed on a substrate. The PUF can be read by creating a magnetization map of the PUF from the signal output of a quantum diamond microscope (QDM) and converting the magnetization map to a numerical sequence.
FILED Tuesday, October 05, 2021
APPL NO 17/494056
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/326 (20130101) Original (OR) Class
G01R 33/0354 (20130101)

Electric Digital Data Processing
G06F 18/213 (20230101)

Image or Video Recognition or Understanding
G06V 20/95 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796673 Beer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Reginald N. Beer (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) N. Reginald Beer (Pleasanton, California);  David Chambers (Livermore, California);  David W. Paglieroni (Pleasanton, California)
ABSTRACT A system for determining a travel path for an autonomous vehicle (“AV”) to travel to a target while avoiding objects (i.e., obstacles) without the use of an imaging system is provided. An object sense and avoid (“OSA”) system detects objects in an object field that is adjacent to the AV and dynamically generates, as the AV travels, a travel path to the target to avoid the objects. The OSA system repeatedly uses sensors to collect sensor data of any objects in the object field. An object detection system then detects the objects and determines their locations based on triangulating ranges to an object as indicated by different sensors. The path planner system then plans a next travel direction for the AV to avoid the detected objects while seeking to minimize the distance traveled. The OSA system then instructs the AV to travel in the travel direction.
FILED Wednesday, July 06, 2016
APPL NO 16/315142
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101)

Unmanned aerial vehicles [UAV]; equipment therefor
B64U 2201/10 (20230101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/48 (20130101)
G01S 13/93 (20130101)
G01S 13/933 (20200101) Original (OR) Class

Systems for Controlling or Regulating Non-electric Variables
G05D 1/106 (20190501)

Traffic Control Systems
G08G 5/045 (20130101)
G08G 5/0069 (20130101)
G08G 5/0078 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796794 Fan et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Jonathan Fan (Los Altos, California);  Jiaqi Jiang (Stanford, California);  Mingkun Chen (Cupertino, California)
ABSTRACT A method for optimization of photonic devices is disclosed. The method includes receiving a set of unconstrained latent variables; mapping the set of unconstrained latent variables to a constrained space to generate a constrained device; calculating the permittivity across each element of the constrained device; determining a permittivity-constrained width gradient based at least partially on the permittivity across each element; and optimizing the set of unconstrained latent variables by at least partially using the permittivity-constrained width gradient.
FILED Tuesday, May 11, 2021
APPL NO 17/317624
ART UNIT 2877 — Optics
CURRENT CPC
Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 11/0228 (20130101)
G01M 11/0242 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/0012 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796841 Martinez et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Nicholas Jacob Martinez (Albuquerque, New Mexico);  Anthony L. Lentine (Albuquerque, New Mexico)
ABSTRACT A thermally tunable microresonator device with enhanced thermal confinement for greater efficiency is provided. A thermal confinement structure is electrically connected in series with the heater element used for tuning the microresonator. The heater element is conformed in a circular arc concentric with the microresonator, the thermal confinement structure comprises two or more tiers, and each tier comprises at least one metal trace conformed in a circular arc concentric with the microresonator.
FILED Wednesday, March 24, 2021
APPL NO 17/210833
ART UNIT 2871 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/025 (20130101)
G02F 1/0147 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797455 Yin et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Jieming Yin (Bellevue, Washington);  Subhash Sethumurugan (Bellevue, Washington);  Yasuko Eckert (Bellevue, Washington)
ABSTRACT A cache of a processor includes a cache controller to implement a cache management policy for the insertion and replacement of cache lines of the cache. The cache management policy assigns replacement priority levels to each cache line of at least a subset of cache lines in a region of the cache based on a comparison of a number of accesses to a cache set having a way that stores a cache line since the cache line was last accessed to a reuse distance determined for the region of the cache, wherein the reuse distance represents an average number of accesses to a given cache set of the region between accesses to any given cache line of the cache set.
FILED Monday, October 14, 2019
APPL NO 16/600897
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 12/126 (20130101)
G06F 12/0855 (20130101)
G06F 12/0871 (20130101)
G06F 12/0891 (20130101) Original (OR) Class
G06F 12/0897 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797881 Arendt et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Dustin Arendt (Richland, Washington);  Zhuanyi Huang (Richland, Washington)
ABSTRACT Explanation apparatus and methods are described. In one aspect, an explanation apparatus includes processing circuity configured to access a source instance which has been classified by a machine learning model; create associations of the source instance with a plurality of training instances; and process the associations of the source instance and the training instances to identify a first subset of the training instances which have less relevance to the classification decision of the source instance by the machine learning model compared with a second subset of the training instances; and an interface configured to communicate information to a user, and wherein the processing circuitry is configured to control the user interface to communicate the second subset of the training instances to the user as evidence to explain the classification of the source instance by the machine learning model.
FILED Thursday, August 29, 2019
APPL NO 16/555530
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Electric Digital Data Processing
G06F 18/2115 (20230101)
G06F 18/24147 (20230101)
G06F 18/24323 (20230101)

Computer Systems Based on Specific Computational Models
G06N 5/045 (20130101)
G06N 20/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798273 Roberts et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Randy S. Roberts (Livermore, California);  John Goforth (Carlsbad, California)
ABSTRACT A system is provided for identifying and quantizing a change in a scene having objects based on comparison of features representing a target object derived from a first image and a second image that includes the target object. The system segments, based on a scene model of the scene, a second image that includes the target object to identify a second area representing the target object within the second image. The system extracts, from the second image, second features for the target object based on the second area. The system determines a second effectiveness of the second features indicating effectiveness of the second features in representing the target object. The system detects a change based on a difference between first features and the second features factoring in a first effectiveness and the second effectiveness.
FILED Friday, March 12, 2021
APPL NO 17/199678
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 18/214 (20230101)
G06F 18/217 (20230101)

Image Data Processing or Generation, in General
G06T 7/174 (20170101)

Image or Video Recognition or Understanding
G06V 10/44 (20220101)
G06V 10/60 (20220101)
G06V 10/462 (20220101)
G06V 10/774 (20220101)
G06V 10/776 (20220101)
G06V 20/13 (20220101) Original (OR) Class
G06V 2201/07 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798702 Brown et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC. (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Michael A. Brown (Chicago, Illinois);  Artem Gelis (Naperville, Illinois);  David Rotsch (Montgomery, Illinois);  Jerry A. Nolen, Jr. (Chicago, Illinois);  Amanda J. Youker (Saint Charles, Illinois)
ABSTRACT A method for obtaining 225AC from 225Ra having the steps of assembling a column having an inorganic stationary phase; priming the column to immobilize 226Ra 225Ra and natural decay products therefrom; immobilizing the 226Ra, 225Ra, 224Ra, and natural decay products therefrom onto a stationary phase within the column; and eluting the column containing the 225Ra with an aqueous sulfate solution to obtain a milking effluent that contains 225AC. Also provided is a method for obtaining pure 225AC from its isotope parents, the method comprising assembling a column having a stationary phase comprising an inorganic material; priming the column with the isotope parents to immobilize 225Ac, and natural decay products of 225AC; immobilizing the 225Ac, and natural decay products therefrom onto the stationary phase within the column 226Ra, 225Ra, 224Ra; and eluting the column containing the 225AC to obtain an effluent that contains the isotope parents.
FILED Wednesday, August 28, 2019
APPL NO 16/554048
ART UNIT 1738 — Printing/Measuring and Testing
CURRENT CPC
Separation
B01D 15/322 (20130101)
B01D 15/363 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/0211 (20130101)
B01J 41/05 (20170101)
B01J 41/10 (20130101)

Production and Refining of Metals; Pretreatment of Raw Materials
C22B 3/42 (20130101)
C22B 60/02 (20130101)
C22B 60/0295 (20130101)

Conversion of Chemical Elements; Radioactive Sources
G21G 1/12 (20130101) Original (OR) Class
G21G 2001/0089 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 5/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798706 Graves
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
Office of Science (DOE-SC)
SLAC National Accelerator Laboratory (SLAC)
Federally Funded Research and Development Center (FFRDC)
Operated by Stanford University (LSJU) at Menlo Park, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Arizona Board of Regents on Behalf Of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) William Graves (Tempe, Arizona)
ABSTRACT A method includes accelerating an electron bunch along a direction of propagation to a relativistic energy and partitioning the electron bunch by transmitting the electron bunch through a grating at the relativistic energy. The grating includes a plurality of alternating narrow portions and wide portions. The narrow portions have a first thickness in a direction substantially parallel to the direction of propagation of the electron bunch, and the wide portions have a second thickness in the direction substantially parallel to the direction of propagation of the electron bunch. The second thickness is greater than the first thickness. The method also includes generating a pulse of light using the partitioned electron bunch.
FILED Friday, July 16, 2021
APPL NO 17/378099
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/20008 (20130101)
G01N 2223/102 (20130101)
G01N 2223/0565 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 1/062 (20130101) Original (OR) Class
G21K 2201/061 (20130101)
G21K 2201/067 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 4/00 (20130101)

X-ray Technique
H05G 2/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798808 Misra et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Shashank Misra (Albuquerque, New Mexico);  Daniel Robert Ward (Calabasas, California);  DeAnna Marie Campbell (Albuquerque, New Mexico);  Tzu-Ming Lu (Albuquerque, New Mexico);  Scott William Schmucker (Albuquerque, New Mexico);  Evan Michael Anderson (Albuquerque, New Mexico);  Andrew Jay Leenheer (Albuquerque, New Mexico);  Jeffrey Andrew Ivie (Albuquerque, New Mexico)
ABSTRACT A method of Atomic Precision Advanced Manufacturing (APAM) is provided, in which a substrate is doped from a dopant precursor gas. The method involves covering a surface of the substrate with a hard mask, selectively removing material from the hard mask such that selected areas of the substrate surface are laid bare, exposing the laid-bare areas to the dopant precursor gas, and heating the substrate so as to incorporate dopant from the dopant precursor gas into the substrate surface.
FILED Monday, June 28, 2021
APPL NO 17/360284
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/223 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798844 Arrington et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Christian Lew Arrington (Albuquerque, New Mexico);  Amber Lynn Dagel (Lafayette, Colorado);  Patrick Sean Finnegan (Albuquerque, New Mexico);  Andrew E. Hollowell (Albuquerque, New Mexico);  Travis Ryan Young (Albuquerque, New Mexico);  Kalin Baca (Albuquerque, New Mexico)
ABSTRACT A method is provided for making gratings of gold or other metal in silicon substrates. The disclosed method may achieve high aspect ratios. According to the disclosed method, a silicon wafer is through-etched. A seed layer of metal is vapor-deposited on one side of the wafer, and a layer of metal is electrodeposited on the seed layer. The electrodeposited metal plugs the trenches and provides a conductive surface for subsequent electrodeposition. The trenches are then filled by electrodeposition from within the trenches, so that the walls of the metal grating grow on the metal plugs.
FILED Friday, October 15, 2021
APPL NO 17/503144
ART UNIT 2817 — Semiconductors/Memory
CURRENT CPC
Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/48 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/3063 (20130101)
H01L 21/76847 (20130101) Original (OR) Class
H01L 21/76873 (20130101)
H01L 21/76877 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799088 Ramaswamy et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan)
ASSIGNEE(S) GM Global Technology Operations LLC (Detroit, Michigan)
INVENTOR(S) Nagappan Ramaswamy (Rochester Hills, Michigan);  Roland J. Koestner (Rochester Hills, Michigan);  Swaminatha P. Kumaraguru (Rochester Hills, Michigan)
ABSTRACT A cathode configured for use within a fuel cell system is provided. The cathode includes a cathode substrate. The cathode further includes a coating disposed upon the cathode substrate and including a fluorocarbon polymer additive configured for sintering at a temperature of less than 200° C. The fluorocarbon polymer additive may be mixed with a catalyst ink coating or may be applied separately as a topcoat layer.
FILED Tuesday, January 11, 2022
APPL NO 17/573089
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8657 (20130101) Original (OR) Class
H01M 4/8663 (20130101)
H01M 4/8828 (20130101)
H01M 4/8885 (20130101)
H01M 2004/8689 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799112 Benicewicz et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Brian C. Benicewicz (Columbia, South Carolina);  Laura Murdock (Columbia, South Carolina);  Lihui Wang (West Columbia, South Carolina);  Fei Huang (West Columbia, South Carolina);  Andrew Pingitore (Columbia, South Carolina)
ABSTRACT Disclosed are redox flow battery membranes, redox flow batteries incorporating the membranes, and methods of forming the membranes. The membranes include a polybenzimidazole gel membrane that is capable of incorporating a high liquid content without loss of structure that is formed according to a process that includes in situ hydrolysis of a polyphosphoric acid solvent. The membranes are imbibed with a redox flow battery supporting electrolyte such as sulfuric acid and can operate at very high ionic conductivities of about 100 mS/cm or greater. Redox flow batteries incorporating the PBI-based membranes can operate at high current densities of about 100 mA/cm2 or greater.
FILED Friday, March 04, 2022
APPL NO 17/686631
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/92 (20130101)
H01M 4/8605 (20130101)
H01M 4/8828 (20130101)
H01M 8/1027 (20130101) Original (OR) Class
H01M 8/1032 (20130101)
H01M 8/1044 (20130101)
H01M 8/1048 (20130101)
H01M 8/1067 (20130101)
H01M 8/1081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799205 Byers
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Kyle J. Byers (Leawood, Kansas)
ABSTRACT A spiral antenna assembly with an integrated feed network and method of manufacturing the same are disclosed. The spiral antenna assembly may comprise a supporting structure integrally formed with a feed network structure, thereby presenting a monolithic structure. A spiral antenna element may be disposed on a bottom surface or a top surface of the supporting structure. The feed network structure may comprise the feed network and project from a center of the top surface of the supporting structure. The feed network may comprise a microstrip balun architecture. The spiral antenna assembly may be formed by additively manufacturing the supporting structure and the feed network structure. A laser direct structuring process may write and activate the spiral antenna element on the supporting structure and the feed network on the feed network structure.
FILED Tuesday, June 07, 2022
APPL NO 17/834594
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 9/27 (20130101) Original (OR) Class
H01Q 9/065 (20130101)
H01Q 15/141 (20130101)
H01Q 21/0087 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799295 Dall'Anese et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Université catholique de Louvain (Louvain-la-Neuve, Belgium)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Universite Catholique de Louvain (Louvain-la-Neuve, Belgium)
INVENTOR(S) Emiliano Dall'Anese (Arvada, Colorado);  Andrey Bernstein (Golden, Colorado);  Andrea Simonetto (Wavre, Belgium)
ABSTRACT An example device includes a processor configured to receive a plurality of voltage values representing respective voltage magnitudes at voltage nodes in a first portion of a power system and determine, for each voltage node, a respective value of first and second voltage-constraint coefficients. The processor is also configured to receive a power value corresponding to a connection point of the first portion of the power system with a second portion of the power system and determine for the connection point, a respective value of first and second power-constraint coefficients. The processor is also configured to cause at least one energy resource connected to the first portion of the power system to modify an output power of the at least one energy resource based on the value of the first and second voltage-constraint coefficients for each voltage node and the value of the first and second power-constraint coefficients.
FILED Friday, February 05, 2021
APPL NO 17/168810
ART UNIT 2117 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/042 (20130101)
G05B 2219/2639 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/00 (20130101)
H02J 3/32 (20130101)
H02J 3/46 (20130101)
H02J 3/381 (20130101) Original (OR) Class
H02J 2203/20 (20200101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 40/70 (20130101)
Y02E 60/00 (20130101)

Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids
Y04S 40/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799384 Takken et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Todd Edward Takken (Brewster, New York);  Xin Zhang (Chappaqua, New York);  Andrew Ferencz (Southborough, Massachusetts)
ABSTRACT A power converter with co-packaged secondary field effect transistors (FETs) are described. The power converter can include a first circuit, a transformer connected to an output of the first circuit, and a second circuit connected to an output of the transformer. The second circuit can include an inductor, a first FET coupled between the transformer and the inductor, and a second FET coupled between the first FET and ground. The first FET and the second FET can be co-packaged as a single package.
FILED Tuesday, January 28, 2020
APPL NO 16/774960
ART UNIT 2839 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 25/074 (20130101)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 3/003 (20210501)
H02M 3/33576 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11800631 Agustsson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) RadiaBeam Technologies, LLC (Santa Monica, California)
ASSIGNEE(S) RadiaBeam Technologies, LLC (Santa Monica, California)
INVENTOR(S) Ronald Agustsson (Venice, California);  Salime Boucher (Santa Monica, California);  Sergey Kutsaev (Santa Monica, California)
ABSTRACT A particle accelerator can include a first waveguide portion and a second waveguide portion. The first waveguide portion can include a first plurality of cell portions and a first iris portion that is disposed between two of the first plurality of cell portions. The first iris portion can include a first portion of an aperture such that the aperture is configured to be disposed about a beam axis. The first waveguide portion can further include a first bonding surface. The second waveguide portion can include a second plurality of cell portions and a second iris portion that is disposed between two of the second plurality of cell portions. The second iris portion can include a second portion of the aperture. The second waveguide portion can include a second bonding surface.
FILED Thursday, August 11, 2022
APPL NO 17/886212
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 7/18 (20130101)
H05H 7/22 (20130101)
H05H 9/02 (20130101) Original (OR) Class
H05H 2007/225 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11793394 Garbin et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee);  University of Leeds (Leeds, United Kingdom)
INVENTOR(S) Nicolo Garbin (Nashville, Tennessee);  Pietro Valdastri (Leeds, United Kingdom);  Keith L. Obstein (Nashville, Tennessee);  Nabil Simaan (Nashville, Tennessee);  Piotr Robert Slawinski (Lincoln, Nebraska)
ABSTRACT A steerable endoscope system includes a continuum manipulator, a plurality of syringes, and a steerable tip. The continuum manipulator includes a plurality of spaced discs and a plurality of backbones each extending through all discs. A bending movement of the continuum manipulator changes a varying linear displacement of each backbone. Each backbone is further coupled to a different one of the syringes such that the linear displacement of each backbone pushes or pulls a piston of the corresponding syringe by a varying amount. The steerable tip includes a plurality of bellows each pneumatically coupled to a different syringe such that movement of the piston of a syringe causes the corresponding bellow to inflate or deflate. Because the distal end of each bellow is fixedly coupled to the same end effector, variations in the amount of inflation or deflation on each bellow causes a bending of the steerable tip.
FILED Friday, December 01, 2017
APPL NO 16/465621
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/0052 (20130101)
A61B 1/0055 (20130101) Original (OR) Class
A61B 1/2733 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/0084 (20130101)
A61M 25/0138 (20130101)
A61M 25/0155 (20130101)
A61M 2025/0085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793439 Lu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Nanshu Lu (Austin, Texas);  Shixuan Yang (Austin, Texas);  Pulin Wang (Austin, Texas)
ABSTRACT Epidermal electronics are non-invasive and non-obstructive skin mounted sensors with mechanical properties matching human epidermis. Their manufacturing process includes photolithography and dry and wet etching within cleanroom facilities. The high cost of manpower, materials, photo masks, and facilities greatly hinders the commercialization potential of disposable epidermal electronics. In contrast, an embodiment of the invention includes a low cost, high throughput, bench top “cut-and-paste” method to complete the freeform manufacture of epidermal sensor system (ESS) in minutes. This versatile method works for many types of thin metal and polymeric sheets and is compatible with many tattoo adhesives or medical tapes. The resultant ESS is highly multimaterial and multifunctional and may measure ECG, EMG, skin temperature, skin hydration, as well as respiratory rate. Also, a stretchable planar coil made of serpentine ribbons can be used as a wireless strain gauge and/or a near field communication (NFC) antenna. Other embodiments are described herein.
FILED Tuesday, April 26, 2022
APPL NO 17/729768
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/25 (20210101) Original (OR) Class
A61B 5/085 (20130101)
A61B 5/296 (20210101)
A61B 5/0537 (20130101)
A61B 5/6833 (20130101)
A61B 2562/02 (20130101)
A61B 2562/06 (20130101)
A61B 2562/12 (20130101)
A61B 2562/125 (20130101)
A61B 2562/0261 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 35/02 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2067/003 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/753 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793672 Humayun et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Mark S. Humayun (Glendale, California);  Aldo Oregon (Los Angeles, California);  Yi Zhang (Los Angeles, California)
ABSTRACT Several embodiments disclosed herein relate to compositions and methods for treating or repairing damage to ocular tissue. In particular, several embodiments relate to patches that interact, e.g., by way of an adhesive, with damaged retinal tissue to repair or mend a hole, tear or detachment of the retina from underlying ocular tissue. Still additional embodiments relate to self-assembling patches.
FILED Monday, November 23, 2020
APPL NO 17/102078
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 9/00727 (20130101) Original (OR) Class

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/24 (20130101)
A61L 27/222 (20130101)
A61L 27/225 (20130101)
A61L 27/227 (20130101)
A61L 2430/16 (20130101)

Compositions of Macromolecular Compounds
C08L 65/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793877 D'Amato et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Anthony R. D'Amato (Troy, New York);  Nicholas Schaub (Germantown, Maryland);  Andrew Sante Fiumara (Fayetteville, New York);  Paul Michael Troiano (Housatonic, Massachusetts);  Jesus Cardenas (Lake Forest, California);  Ryan J. Gilbert (Troy, New York)
ABSTRACT Embodiments of the invention relate generally to electrospun fibers and, more particularly, to the controlled release of an active pharmaceutical ingredient (API) from electrospun fiber scaffolds (EFSs).
FILED Tuesday, October 04, 2016
APPL NO 15/766585
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/70 (20130101)
A61K 31/455 (20130101)
A61K 47/34 (20130101) Original (OR) Class
A61K 2300/00 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/44 (20130101)
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/54 (20130101)
A61L 2300/434 (20130101)
A61L 2300/602 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/003 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 1/10 (20130101)
D01F 6/68 (20130101)
D01F 6/625 (20130101)

Finishing or Dressing of Filaments, Yarns, Threads, Cords, Ropes or the Like
D02J 13/00 (20130101)
D02J 13/003 (20130101)

Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding
D04H 1/728 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794166 Kuhn et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
INVENTOR(S) John N. Kuhn (Tampa, Florida);  Debtanu Maiti (Tampa, Florida);  Yolanda A. Daza (Beaverton, Oregon);  Bryan J. Hare (Orlando, Florida);  Adela E. Ramos (Tampa, Florida);  Venkat R. Bhethanabotla (Tampa, Florida)
ABSTRACT Perovskite oxides and catalysts containing the perovskite oxides are provided for the thermochemical conversion of carbon dioxide to carbon monoxide. The perovskite oxides can exhibit large carbon monoxide production rates and/or low carbon monoxide production onset temperatures as compared to existing materials. Reactors are provided containing the perovskite oxides and catalysts, as well as methods of use thereof for the thermochemical conversion of carbon dioxide to carbon monoxide.
FILED Friday, February 26, 2021
APPL NO 17/186528
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/002 (20130101) Original (OR) Class
B01J 2523/23 (20130101)
B01J 2523/25 (20130101)
B01J 2523/31 (20130101)
B01J 2523/67 (20130101)
B01J 2523/72 (20130101)
B01J 2523/842 (20130101)
B01J 2523/845 (20130101)
B01J 2523/3706 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/40 (20170801)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 17/32 (20200101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794178 Veige et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Adam S. Veige (Gainesville, Florida);  Stella Almeida Gonsales (Gainesville, Florida)
ABSTRACT A tetraanionic OCO pincer ligand metal-oxo-alkylidene complex is prepared from a trianionic pincer ligand supported metal-alkylidyne. The metal can be tungsten or other group 5-7 transition metal. The tetraanionic pincer ligand metal-oxo-alkylidene complex, a trianionic OCO pincer ligand metal complex, or a trianionic ONO pincer ligand metal complex can be used to polymerize cycloalkenes. The poly(cycloalkene)s are predominantly cis-alkene macrocyclics.
FILED Tuesday, January 18, 2022
APPL NO 17/577510
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/223 (20130101) Original (OR) Class
B01J 31/2243 (20130101)
B01J 31/2265 (20130101)
B01J 31/2286 (20130101)
B01J 2231/14 (20130101)
B01J 2231/543 (20130101)
B01J 2531/66 (20130101)
B01J 2531/0244 (20130101)
B01J 2540/10 (20130101)
B01J 2540/225 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 11/00 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 4/69 (20130101)
C08F 4/78 (20130101)
C08F 4/69206 (20130101)
C08F 32/04 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/08 (20130101)
C08G 2261/13 (20130101)
C08G 2261/418 (20130101)
C08G 2261/3324 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794334 Okamura et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Allison M. Okamura (Mountain View, California);  Sean Follmer (Palo Alto, California);  Elliot W. Hawkes (Santa Barbara, California);  Zachary Hammond (Stanford, California);  Nathan Scot Usevitch (Stanford, California);  Mac Schwager (Stanford, California);  James Ballard (Menlo Park, California)
ABSTRACT Adaptable and customizable truss-like robots are provided. The robotic truss has robotic roller modules configured to translate along one or more pliable member and therewith control the shape or design of the robot.
FILED Thursday, September 10, 2020
APPL NO 17/017299
ART UNIT 2846 — Printing/Measuring and Testing
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/08 (20130101)
B25J 9/0012 (20130101)
B25J 9/0075 (20130101) Original (OR) Class
B25J 9/126 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794377 Nutt et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Steven Nutt (Irvine, California);  Lessa Grunenfelder (Los Angeles, California);  Timotei Centea (Venice, California);  Mark Anders (Los Angeles, California);  William Thomas Edwards (Fullerton, California);  Sarah Grace Katz Schechter (Los Angeles, California)
ABSTRACT Methods, apparatuses, and systems for making prepregs are disclosed. A method may include depositing a resin material onto a surface of a fiber bed and forming a number of discrete resin regions thereon. A distance between the resin regions may be measured to provide desired exposed portions of the surface to facilitate permeation of air through the exposed portions of the surface in a direction perpendicular to a plane of the fiber bed during a curing process of the prepreg.
FILED Tuesday, January 04, 2022
APPL NO 17/568664
ART UNIT 1785 — Miscellaneous Articles, Stock Material
CURRENT CPC
Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics
B29B 15/122 (20130101) Original (OR) Class

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/20 (20130101)
B29C 70/443 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2307/04 (20130101)
B29K 2309/08 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/24 (20130101)
C08J 2361/10 (20130101)
C08J 2363/00 (20130101)
C08J 2375/04 (20130101)
C08J 2379/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795208 Doudna et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A Doudna (Berkeley, California);  Kyle E. Watters (Moraga, California);  Christof Fellmann (Berkeley, California);  Haridha Shivram (Berkeley, California)
ABSTRACT The present disclosure provides polypeptides that inhibit activity of a CRISPR/Cas effector polypeptide, nucleic acids encoding the polypeptides, and systems comprising the polypeptides and/or nucleic acids encoding the polypeptides. The present disclosure provides methods of inhibiting activity of a CRISRP/Cas effector polypeptide.
FILED Wednesday, September 30, 2020
APPL NO 17/039195
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/8107 (20130101) Original (OR) Class
C07K 2319/09 (20130101)
C07K 2319/40 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795211 Sok et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) International AIDS Vaccine Initiative (New York, New York);  The Scripps Research Institute (La Jolla, California);  The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) International AIDS Vaccine Initiative (New York, New York);  The Scripps Research Institute (La Jolla, California);  THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S) Devin Sok (New York, New York);  Dennis R. Burton (La Jolla, California);  Vaughn V. Smider (La Jolla, California);  Ian Wilson (La Jolla, California);  Michael Criscitiello (College Station, Texas);  Waithaka Mwangi (College Station, Texas)
ABSTRACT The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab′)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody.
FILED Thursday, July 12, 2018
APPL NO 16/630768
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/162 (20130101)
C07K 16/1063 (20130101) Original (OR) Class
C07K 2317/10 (20130101)
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/33 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
C07K 2319/02 (20130101)
C07K 2319/31 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795248 Pyun
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Dong-Chul Pyun (Tucson, Arizona)
ABSTRACT Sulfur copolymers and methods of synthesizing said sulfur copolymers are described herein. Sulfur monomers copolymerize with epoxide or vinylic moieties the epoxy-functionalized styrenic comonomers to form a crosslinked network of the sulfur copolymer. Sulfur copolymers having high sulfur content are used as raw materials in 3D printing. Chalcogenide-based copolymers can utilize selenium to provide for the optical properties. Using an inverse vulcanization method, chalcogenic sulfur copolymers are used to prepare chemically stable polymer plastic materials with tunable optical and thermochemical properties. Optical substrates, such as films, waveguides, and molded (nano-, micro-) objects and lenses, are constructed from sulfur copolymers via 3D printing and are substantially transparent in the visible and infrared spectrum.
FILED Friday, January 22, 2021
APPL NO 17/156238
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 212/22 (20200201)
C08F 212/26 (20200201)
C08F 212/30 (20200201) Original (OR) Class

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 75/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795281 Jiang et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S) Peng Jiang (Gainesville, Florida);  Sin-Yen Leo (Hillsboro, Oregon);  Calen Leverant (Gainesville, Florida);  Danielle Liu (Nashville, Tennessee);  Yin Fang (Gainesville, Florida)
ABSTRACT Described herein are methods and compositions relating to tunable nanoporous coatings. In certain aspects, described herein are methods and compositions wherein a tunable nanoporous coating comprises a tunable nanoporous membrane which transitions from opaque to transparent upon the application of force, and from transparent to opaque after washing with a solvent.
FILED Wednesday, April 14, 2021
APPL NO 17/230160
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Separation
B01D 69/125 (20130101)
B01D 71/40 (20130101)
B01D 2321/18 (20130101)
B01D 2323/24 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 22/1006 (20200201)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101) Original (OR) Class
C08J 7/02 (20130101)
C08J 2335/02 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/111 (20130101)
G02B 5/0247 (20130101)
G02B 5/0268 (20130101)
G02B 5/0294 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795468 Hannapel et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa);  Indian Institute of Science Education and Research (IISER) (Maharashtra, India)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa);  Indian Institute of Science Education and Research (IISER) (Pune, India)
INVENTOR(S) David J. Hannapel (Ames, Iowa);  Anjan K. Banerjee (Pune, India)
ABSTRACT The present invention relates to a nucleic acid construct. The nucleic acid construct includes a nucleic acid molecule configured to silence or reduce the expression of StBEL11 and/or StBEL29 and variants thereof, a 5′ DNA promoter sequence, and a 3′ terminator sequence, where the first nucleic acid molecule, the promoter sequence, and the terminator sequence are operatively coupled to permit transcription of the first nucleic acid molecule. The present invention is also directed to vectors, host cells, transgenic plants, and transgenic plant seeds, as well as non-transgenic mutant plants, and methods for altering tuber yield in a plant.
FILED Friday, January 11, 2019
APPL NO 16/246321
ART UNIT 1662 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8226 (20130101)
C12N 15/8234 (20130101)
C12N 15/8261 (20130101) Original (OR) Class

Technologies for Adaptation to Climate Change
Y02A 40/146 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795472 Doudna et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A. Doudna (Berkeley, California);  Jillian Banfield (Berkeley, California);  David Burstein (Berkeley, California);  Lucas Benjamin Harrington (Berkeley, California);  Steven C. Strutt (Berkeley, California)
ABSTRACT The present disclosure provides CasX proteins, nucleic acids encoding the CasX proteins, and modified host cells comprising the CasX proteins and/or nucleic acids encoding same. CasX proteins are useful in a variety of applications, which are provided. The present disclosure provides CasX guide RNAs that bind to and provide sequence specificity to the CasX proteins, nucleic acids encoding the CasX guide RNAs, and modified host cells comprising the CasX guide RNAs and/or nucleic acids encoding same. CasX guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides archaeal Cas9 polypeptides and nucleic acids encoding same, as well as their associated archaeal Cas9 guide RNAs and nucleic acids encoding same.
FILED Friday, May 24, 2019
APPL NO 16/422824
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 19/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/06 (20130101)
C07K 2319/09 (20130101)
C07K 2319/20 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/1007 (20130101)
C12N 9/1025 (20130101)
C12N 15/52 (20130101)
C12N 15/62 (20130101)
C12N 15/74 (20130101)
C12N 15/85 (20130101)
C12N 15/86 (20130101)
C12N 15/88 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101)
C12N 15/902 (20130101)
C12N 15/8509 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2740/13043 (20130101)
C12N 2740/16043 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795579 Yu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Abalone Bio, Inc. (Richmond, California)
ASSIGNEE(S) Abalone Bio, Inc. (Richmond, California)
INVENTOR(S) Richard Yu (Richmond, California);  Carlos Gustavo Pesce (Richmond, California);  Rodrigo Baltanas (Richmond, California);  Brett Robison (Richmond, California)
ABSTRACT Compositions and methods for displaying antibodies in the periplasmic space of yeast cells are disclosed. In particular, antibodies are linked to a cell membrane-spanning transmembrane domain, a cell-membrane associated protein domain that is on the external face of the yeast cell membrane, a protein that binds to the inner face of the yeast cell wall, or a periplasmic protein in order to display the antibodies in the yeast periplasmic space. In addition, a target protein of interest can be coexpressed in yeast such that it is localized to the plasma membrane or periplasmic space and accessible to binding by displayed antibodies. The disclosure further relates to high-throughput screening of antibody libraries using yeast cell periplasmic display.
FILED Monday, December 10, 2018
APPL NO 16/771128
ART UNIT 1675 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Peptides
C07K 16/00 (20130101)
C07K 16/28 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1037 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 30/04 (20130101)
C40B 30/06 (20130101)
C40B 40/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796304 Jin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Haojian Jin (Pittsburgh, Pennsylvania);  Jingxian Wang (Pittsburgh, Pennsylvania);  Swarun Kumar Suresh Kumar (Pittsburgh, Pennsylvania);  Jason I. Hong (Pittsburgh, Pennsylvania)
ABSTRACT A method, system, and computer program product is provided for tracking the shape of a surface. The method includes generating a first plurality of surface models based on the surface, each surface model associated with surface parameter values and representing a different shape, determining an estimated position of the plurality of RF transponders on each surface model of the first plurality of surface models, communicating at least one activation signal to the plurality of RF transponders arranged on the surface, the surface comprising an unknown shape, receiving a plurality of response signals from at least a subset of the plurality of RF transponders, determining radio environment parameters for each surface model of the first plurality of surface models, and determining at least one selected surface model of the first plurality of surface models.
FILED Wednesday, April 24, 2019
APPL NO 17/050010
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 7/16 (20130101)
G01B 7/287 (20130101) Original (OR) Class

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/75 (20130101)
G01S 13/89 (20130101)
G01S 13/878 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796472 He et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
Division of Materials Research (DMR)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Chen He (Chicago, Illinois);  David J. Weinberg (San Diego, California);  Emily A. Weiss (Evanston, Illinois);  Jeremiah Yoonsung Kim (Glenview, Illinois);  Chen Wang (Evanston, Illinois);  Andrew Lee (Evanston, Illinois)
ABSTRACT The present technology is directed to the nanoparticles for use as molecular environmental sensors. The nanoparticles comprise a photoluminescence core and a plurality of ligands bound to the core and forming a quencher permeable ligand shell. The ligands comprise a reactive or charged moiety capable of being modulated between a first stand and a second state, and the proportion of ligands in each state determine the permeability of the ligand shell to a photoluminescence quencher.
FILED Tuesday, October 19, 2021
APPL NO 17/505392
ART UNIT 1796 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)
B82Y 20/00 (20130101)
B82Y 40/00 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 21/21 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2004/64 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101) Original (OR) Class
G01N 21/6489 (20130101)
G01N 2021/6432 (20130101)

Organic electric solid-state devices
H10K 50/115 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796473 Gangopadhyay et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Shubhra Gangopadhyay (Columbia, Missouri);  Sangho Bok (Washington, Utah);  Cherian Joseph Mathai (Columbia, Missouri);  Keshab Gangopadhyay (Columbia, Missouri);  Sheila Grant (Columbia, Missouri);  Aaron Wood (Tucson, Arizona);  Syed Barizuddin (Columbia, Missouri)
ABSTRACT The invention broadly relates techniques for imaging and medical diagnosis and, more particularly, to the fabrication of flexible plasmonic gratings and the use thereof in detection of biomarkers. A first aspect of the invention provides for techniques for the fabrication of novel, flexible plasmonic gratings that can be inexpensively fabricated onto fiber optic cables, flexible films and substrates with non-uniform surfaces to enhance the imaging resolution. A second aspect of the invention provides for an ultra¬high sensitivity (single molecule counting) biomarker detection platform useable for medical diagnosis based on a fluorescent sandwich ELISA assay performed on a plasmonic grating platform incorporated with a fluorescence detection unit.
FILED Wednesday, July 11, 2018
APPL NO 16/614573
ART UNIT 1677 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 40/00 (20130101)

Peptides
C07K 16/1289 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/554 (20130101)
G01N 21/648 (20130101) Original (OR) Class
G01N 21/6428 (20130101)
G01N 2021/6439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796499 Xiao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Science Foundation (NSF)
APPLICANT(S) Yi Xiao (Cary, North Carolina);  Yingzhu Liu (Wuhan, China PRC);  Juan Canoura (Hialeah Gardens, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Yi Xiao (Cary, North Carolina);  Yingzhu Liu (Wuhan, China PRC);  Juan Canoura (Hialeah Gardens, Florida)
ABSTRACT The subject invention provides methods for fabricating electrochemical aptamer-based (E-AB) sensors with enhanced sensitivity, signal-to-noise ratios, LOD, and improved stability and reproducibility. The subject invention also provides methods for aptamer immobilization on the surface of the electrode, which favors sufficient spacing between aptamers at the microscale to achieve optimal target recognition, folding, and signal transduction. The E-AB sensors of the subject invention provide superior sensing regardless of the sequence or structure of the bound aptamers or the physiochemical properties of the target.
FILED Tuesday, December 13, 2022
APPL NO 18/065118
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3276 (20130101) Original (OR) Class
G01N 27/3277 (20130101)
G01N 33/5308 (20130101)
G01N 33/5438 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796798 Gopinath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Juliet Gopinath (Boulder, Colorado);  Mo Zohrabi (Boulder, Colorado);  Victor M. Bright (Boulder, Colorado);  Omkar Supekar (Boulder, Colorado);  Robert H. Cormack (Erie, Colorado);  Emily Gibson (Boulder, Colorado);  Connor McCullough (Denver, Colorado)
ABSTRACT The present disclosure relates generally to methods and systems useful in imaging applications, especially biological imaging applications, and applications in the metrology, atmospheric, scientific and medical fields. In one aspect, the disclosure provides a method of imaging an object, including illuminating the object with incident radiation through one or more adaptive optical elements; receiving transmitted radiation from the object at a photodetector to provide a base image; and performing the following steps one or more times: adjusting the one or more adaptive optical elements, the adjustment including modifying an optical transfer function of the one or more adaptive optical elements, and receiving transmitted radiation from the object at the photodetector to provide an adjusted image; wherein the adjustment and receiving steps are performed until the adjusted image has substantially reduced aberrations compared to the base image.
FILED Wednesday, October 03, 2018
APPL NO 16/753615
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101)
G02B 27/0068 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797611 Yu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) International Business Machines Corporation (Armonk, New York);  University of Notre Dame (Notre Dame, Indiana)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Wenhao Yu (Mishawaka, Indiana);  Lingfei Wu (Elmsford, New York);  Yu Deng (Yorktown Heights, New York);  Qingkai Zeng (Granger, Indiana);  Ruchi Mahindru (Elmsford, New York);  Sinem Guven Kaya (New York, New York);  Meng Jiang (Granger, Indiana)
ABSTRACT An approach for a non-factoid question answering framework across tasks and domains may be provided. The approach may include training a multi-task joint learning model in a general domain. The approach may also include initializing the multi-task joint learning model in a specific target domain. The approach may include tuning the joint learning model in the target domain. The approach may include determining which task of the multiple tasks is more difficult for the multi-task joint learning model to learn. The approach may also include dynamically adjusting the weights of the multi-task joint learning model, allowing the model to concentrate on learning the more difficult learning task.
FILED Wednesday, July 07, 2021
APPL NO 17/369040
ART UNIT 2167 — Data Bases & File Management
CURRENT CPC
Electric Digital Data Processing
G06F 16/90332 (20190101) Original (OR) Class
G06F 18/2431 (20230101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Image or Video Recognition or Understanding
G06V 30/418 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797667 Mishra et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
INVENTOR(S) Prabhat Kumar Mishra (Gainesville, Florida);  Thelijjagoda S N Charles (Gainesville, Florida);  Yangdi Lyu (Gainesville, Florida)
ABSTRACT Various examples are provided related to software and hardware architectures that enable lightweight and real-time Denial-of-Service (DoS) and Distributed Denial-of-Service (DDoS) attack detection. In one example, among others, a method for detection and localization of denial-of-service (DoS) attacks includes detecting, by a router of an intellectual property (IP) core in a network-on-chip (NoC) based system-on-chip (SoC) architecture, a compromised packet stream based at least in part upon a packet arrival curve (PAC) associated with the router; identifying, by the IP core, a candidate IP core in the NoC as a potential attacker based at least in part upon a destination packet latency curve (DLC) associated with the IP core; and transmitting, by the router, a notification message indicating that the candidate IP core is the potential attacker to a router of the candidate IP core.
FILED Friday, June 26, 2020
APPL NO 16/913850
ART UNIT 2493 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/552 (20130101) Original (OR) Class
G06F 2221/034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797873 King et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Atom Computing Inc. (Berkeley, California)
ASSIGNEE(S) Atom Computing Inc. (Berkeley, California)
INVENTOR(S) Jonathan King (Berkeley, California);  Benjamin Bloom (Berkeley, California);  Brian Lester (Berkeley, California)
ABSTRACT The present disclosure provides methods and systems for performing non-classical computations. The methods and systems generally use a plurality of spatially distinct optical trapping sites to trap a plurality of atoms, one or more electromagnetic delivery units to apply electromagnetic energy to one or more atoms of the plurality to induce the atoms to adopt one or more superposition states of a first atomic state and a second atomic state, one or more entanglement units to quantum mechanically entangle at least a subset of the one or more atoms in the one or more superposition states with at least another atom of the plurality, and one or more readout optical units to perform measurements of the superposition states to obtain the non-classical computation.
FILED Wednesday, January 06, 2021
APPL NO 17/143030
ART UNIT 2872 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/33 (20130101)

Optical Computing Devices;
G06E 3/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798589 Singer et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  FOLIO PHOTONICS, INC. (Solon, Ohio)
INVENTOR(S) Kenneth Singer (Cleveland, Ohio);  Irina Shiyanovskaya (Solon, Ohio)
ABSTRACT An optical information storage medium includes a substrate and a multilayer polymeric film. The multilayer polymeric film has a first surface and an opposite second surface that extend the length of the multilayer polymeric film. The second surface is adhered to a surface of the substrate. The multilayer polymeric film includes a plurality of coextruded alternating polymeric active data storage layers and polymeric buffer layers.
FILED Thursday, March 12, 2020
APPL NO 17/438820
ART UNIT 2625 — Selective Visual Display Systems
CURRENT CPC
Information Storage Based on Relative Movement Between Record Carrier and Transducer
G11B 7/26 (20130101)
G11B 7/0052 (20130101)
G11B 7/0079 (20130101)
G11B 7/242 (20130101)
G11B 7/24027 (20130101)
G11B 7/24038 (20130101) Original (OR) Class
G11B 7/24056 (20130101)
G11B 7/24065 (20130101)
G11B 2007/0013 (20130101)
G11B 2007/24624 (20130101)
G11B 2007/240025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798706 Graves
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
Office of Science (DOE-SC)
SLAC National Accelerator Laboratory (SLAC)
Federally Funded Research and Development Center (FFRDC)
Operated by Stanford University (LSJU) at Menlo Park, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) Arizona Board of Regents on Behalf Of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) William Graves (Tempe, Arizona)
ABSTRACT A method includes accelerating an electron bunch along a direction of propagation to a relativistic energy and partitioning the electron bunch by transmitting the electron bunch through a grating at the relativistic energy. The grating includes a plurality of alternating narrow portions and wide portions. The narrow portions have a first thickness in a direction substantially parallel to the direction of propagation of the electron bunch, and the wide portions have a second thickness in the direction substantially parallel to the direction of propagation of the electron bunch. The second thickness is greater than the first thickness. The method also includes generating a pulse of light using the partitioned electron bunch.
FILED Friday, July 16, 2021
APPL NO 17/378099
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/20008 (20130101)
G01N 2223/102 (20130101)
G01N 2223/0565 (20130101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 1/062 (20130101) Original (OR) Class
G21K 2201/061 (20130101)
G21K 2201/067 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 4/00 (20130101)

X-ray Technique
H05G 2/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798816 Ahmed et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Omar Saad Ahmed (Orlando, Florida);  Tengfei Jiang (Orlando, Florida)
ABSTRACT A method for isolating at least one conductive via from a surrounding glass substrate is provided. A support layer is formed over at least one surface of the glass substrate. Thereafter, the glass substrate is removed. As a result, the at least one conductive via can be analyzed without interference from the glass substrate.
FILED Friday, May 28, 2021
APPL NO 17/333373
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/486 (20130101) Original (OR) Class
H01L 21/4864 (20130101)
H01L 22/32 (20130101)
H01L 23/15 (20130101)
H01L 23/49827 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799091 Roberts et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
APPLICANT(S) Clemson University (Clemson, South Carolina)
ASSIGNEE(S) Clemson University (Clemson, South Carolina)
INVENTOR(S) Mark E. Roberts (Clemson, South Carolina);  Robert K. Emmett (Clemson, South Carolina);  Stephen E. Creager (Clemson, South Carolina)
ABSTRACT Provided herein is a redox flow battery comprising an anode comprising anodic redox mediators; a negative electrolyte tank comprising an anolyte; and an anode pump capable of circulating the anolyte through the anode. The redox flow battery further comprises a cathode comprising cathodic redox mediators; a positive electrolyte tank comprising a catholyte and a cathode pump capable of circulating the catholyte through the cathode. A separator is between the anode and cathode.
FILED Wednesday, April 07, 2021
APPL NO 17/224429
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/9008 (20130101) Original (OR) Class
H01M 8/08 (20130101)
H01M 8/188 (20130101)
H01M 2004/8684 (20130101)
H01M 2004/8689 (20130101)
H01M 2300/0011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799673 Ganji et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida);  TECHNISCHE UNIVERSITAET BERLIN (Berlin, Germany)
INVENTOR(S) Fatemeh Ganji (Gainesville, Florida);  Shahin Tajik (Gainesville, Florida);  Jean-Pierre Seifert (Werder Havel, Germany);  Domenic Forte (Gainesville, Florida);  Mark M. Tehranipoor (Gainesville, Florida)
ABSTRACT Combined physical unclonable function (PUFs); methods, apparatuses, systems, and computer program products for enrolling combined PUFs; and methods, apparatuses, systems, and computer program products for authenticating a device physically associated with a combined PUF are described. In an example embodiment, a combined PUF includes a plurality of PUFs and one or more logic gates. Each PUF includes a plurality of stages and an arbiter configured to generate a single PUF response based on response portions generated by the plurality of stages. The one or more logic gates are configured to combine the single PUF response for each of the plurality of PUFs in accordance with a combination function to provide a combined response.
FILED Tuesday, April 07, 2020
APPL NO 16/841873
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 19/0963 (20130101)
H03K 19/1737 (20130101)
H03K 19/17748 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/002 (20130101)
H04L 9/0866 (20130101)
H04L 9/3271 (20130101)
H04L 9/3278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799674 Cambou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNVERSITY (Flagstaff, Arizona)
INVENTOR(S) Bertrand F Cambou (Flagstaff, Arizona);  Fatemeh Afghah (Flagstaff, Arizona);  Sareh Assiri (Flagstaff, Arizona);  Ashwija Korenda (Flagstaff, Arizona)
ABSTRACT Systems and methods of correcting errors in encrypted communication between a server and client devices using keyless encryption schemes are disclosed. Client devices with arrays of physical-unclonable-function devices respond to challenges from a server. Characteristics of the arrays are stored by the server during a secure enrollment process. To send an encrypted message, the server generates a message digest, extracts data from the stored arrays on the basis of the message digest, applies error correction codes to the message, encrypts the message with the extracted data, and sends the message to a client. The server may receive a handshake containing all or part of the message digest, measures its PUF, and decrypts and decodes the message.
FILED Friday, December 03, 2021
APPL NO 17/542118
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0869 (20130101)
H04L 9/3242 (20130101)
H04L 9/3278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11800205 Koppal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
INVENTOR(S) Sanjeev Jagannatha Koppal (Gainesville, Florida);  Zaid Tasneem (Gainesville, Florida);  Dingkang Wang (Gainesville, Florida);  Huikai Xie (Gainesville, Florida);  Brevin Jeffery Tilmon (Gainesville, Florida)
ABSTRACT Provided is a camera system to obtain high resolution imagery on multiple regions of interest even when the regions of interest are ate different focal depths and in different viewing directions. Embodiments include a high speed camera that operates by reflecting a beam of interest corresponding to a scene of interest into a high-speed passive sensor from a dynamic optical modulator. Embodiments described herein provide a foveating camera design that distributes resolution onto regions of interest by imaging reflections off a scanning micro-electromechanical system (MEMS) mirror. MEMS mirrors are used herein to modulate viewing direction. Embodiments include a camera capturing reflections off of a tiny, fast moving mirror.
FILED Thursday, April 09, 2020
APPL NO 16/844597
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 26/0841 (20130101)

Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor
G03B 39/04 (20130101)

Image Data Processing or Generation, in General
G06T 5/003 (20130101)
G06T 7/80 (20170101)

Pictorial Communication, e.g Television
H04N 23/45 (20230101) Original (OR) Class
H04N 23/55 (20230101)
H04N 23/66 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11800258 Bobda et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Christophe Bobda (Gainesville, Florida);  Pankaj Bhowmik (Gainesville, Florida);  Md Jubaer Hossain Pantho (Gainesville, Florida)
ABSTRACT Methods and systems are directed to enabling CNN operation close to an image sensor and facilitating CNN inference near the image sensor. The system includes, in part, a digital image sensor and a plurality of processing layers that include, in part, an attention-based preprocessing layer (APL), an inference computation layer (ICL), and a fully connected layer. The digital image sensor can include, in part, a plurality of regions and each region can be processed by region processing units disposed in the APL/ICL in parallel. Each region processing unit disposed in the APL can include, in part, an attention module that determines whether the corresponding region is a relevant region. The region processing units disposed in the APL transmit only relevant data to corresponding region processing units in the ICL and only activate the corresponding region processing units in the ICL for relevant regions. The ICL can include, in part, two convolution layers.
FILED Wednesday, October 06, 2021
APPL NO 17/495420
ART UNIT 2698 — Selective Visual Display Systems
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 5/04 (20130101)

Pictorial Communication, e.g Television
H04N 25/79 (20230101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11793130 Buhler et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Charles R. Buhler (Merritt Island, Florida);  Jerry J. Wang (Melbourne, Florida)
ABSTRACT The subject invention is an electrostatic plant watering system for the delivery of water and nutrients to the roots of plants. The system provides water or another fluid from a fluid source or container using a pump. The pump provides a pressurized fluid at a constant flow rate through a nozzle at a low pressure, which sprays a fine mist of particles through a conductive metallic ring that is electrically charged by a voltage source. As the fluid particles pass through the center of the electrically charged ring, the particles themselves become charged, allowing them to attach to the roots of a target plant positioned at a selected distance away from the electrostatic plant watering system.
FILED Wednesday, November 10, 2021
APPL NO 17/523522
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 29/00 (20130101) Original (OR) Class
A01G 31/02 (20130101)

Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 5/10 (20130101)
B05B 5/16 (20130101)
B05B 5/087 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11794420 Huang et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Luna Labs USA, LLC (Charlottesville, Virginia)
ASSIGNEE(S) LUNA LABS USA, LLC (Charlottesvile, Virginia)
INVENTOR(S) Jianhua Huang (Blacksburg, Virginia);  Daniel Robert Metrey (Blacksburg, Virginia)
ABSTRACT Advanced single vacuum bag (ASVB) fabrication methods and assemblies are provided to manufacture and repair polymer composites whereby a rigid check plate is mounted over an uncured laminate by a thermally collapsible check plate stand. The check plate stand thereby maintains a gap between the check plate and the uncured laminate during first stage processing conditions, yet is capable of thermally collapsing during subsequent second stage processing conditions to thereby allow the check plate to fall into compressive contact with the uncured laminate After the check plate collapses onto the uncured laminate, the compressive force of the check plate will be transferred to the laminate to consolidate the laminate as desired and thereby form an at least partially cured polymer composite structure of high quality.
FILED Monday, June 01, 2020
APPL NO 17/616094
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/342 (20130101) Original (OR) Class
B29C 70/541 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2063/00 (20130101)
B29K 2307/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795281 Jiang et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida)
INVENTOR(S) Peng Jiang (Gainesville, Florida);  Sin-Yen Leo (Hillsboro, Oregon);  Calen Leverant (Gainesville, Florida);  Danielle Liu (Nashville, Tennessee);  Yin Fang (Gainesville, Florida)
ABSTRACT Described herein are methods and compositions relating to tunable nanoporous coatings. In certain aspects, described herein are methods and compositions wherein a tunable nanoporous coating comprises a tunable nanoporous membrane which transitions from opaque to transparent upon the application of force, and from transparent to opaque after washing with a solvent.
FILED Wednesday, April 14, 2021
APPL NO 17/230160
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Separation
B01D 69/125 (20130101)
B01D 71/40 (20130101)
B01D 2321/18 (20130101)
B01D 2323/24 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 22/1006 (20200201)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101) Original (OR) Class
C08J 7/02 (20130101)
C08J 2335/02 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/111 (20130101)
G02B 5/0247 (20130101)
G02B 5/0268 (20130101)
G02B 5/0294 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795536 Thomsen, III et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Donald L. Thomsen, III (Yorktown, Virginia);  Sankara N. Sankaran (Yorktown, Virginia);  Joel A. Alexa (Hampton, Virginia)
ABSTRACT Methods for making layered materials and layered materials including high atomic number metals and metal alloys adhered to surfaces are provided. Such surfaces may be oxygen or hydroxyl rich surfaces. Certain methods include depositing a tie down layer of a first metal or metal alloy particles onto a first surface of base material and depositing a high atomic number metal or metal alloy layer onto the first surface after depositing the tie down layer, wherein particles comprising the high atomic number metal or metal alloy layer have a higher atomic number than the first metal or metal alloy particles.
FILED Friday, July 24, 2020
APPL NO 16/938177
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 15/043 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 4/02 (20130101)
C23C 4/08 (20130101) Original (OR) Class
C23C 4/134 (20160101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796175 Zambon et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Combustion Research and Flow Technology, Inc. (Pipersville, Pennsylvania)
ASSIGNEE(S) Combustion Research and Flow Technology, Inc. (Pipersville, Pennsylvania)
INVENTOR(S) Andrea C. Zambon (Philadelphia, Pennsylvania);  Balaji Muralidharan (Clinton, New Jersey);  William H. Calhoon, Jr. (Huntsville, Alabama);  Ashvin Hosangadi (Jamison, Pennsylvania)
ABSTRACT A method for designing a combustion system which emits less of at least one environmentally-harmful emission is presented. In a describing step, an injector which introduces a fuel into a combustion chamber is described via a CFD code. In a modeling step, combustion kinetics of the fuel are modeled via a pre-processing code as the fuel mixes and reacts with an oxidizer. In a first selecting step, at least one primary scalar is derived during the modeling of the combustion kinetics. In a performing step, a table look-up is performed to obtain at least one data from a look-up database based on the primary scalar. In a second selecting step, at least one secondary scalar is selected in addition to the primary scalar(s). In a specifying step, at least one chemical pathway of formation or destruction for the secondary scalar is specified via a chemistry manager wherein the secondary scalar is representative of the environmentally-harmful emission(s) of the chemical pathway(s). In a utilizing step, the data is utilized to evaluate the chemical pathway(s) to quantify the environmentally-harmful emission(s). In an identifying step, an improvement to the combustion system is identified which reduces the environmentally-harmful emission(s).
FILED Friday, July 01, 2022
APPL NO 18/009118
ART UNIT 2148 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/22 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/42 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 30/17 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796306 Bathel et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Brett F. Bathel (Yorktown, Virginia);  Joshua M. Weisberger (Newport News, Virginia)
ABSTRACT An adjustable beam directing optical system for a focused laser differential interferometer (FLDI) instrument according to various aspects of the present technology may include an optical half waveplate to achieve an incident linear polarization orientation with equal components of laser intensity aligned to the vertical and horizontal axis of the optical system, and an optical prism for splitting these components of an incident laser beam into two orthogonally-polarized beams equally about an optical axis of the FLDI instrument. A series of beam realignment devices positioned downstream of the optical prism are configured to selectively direct each beam to a predetermined location.
FILED Friday, September 25, 2020
APPL NO 17/032341
ART UNIT 2872 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02001 (20130101)
G01B 9/02015 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 5/3083 (20130101)
G02B 7/003 (20130101)
G02B 7/1805 (20130101)
G02B 27/285 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796457 Li et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of NASA (, None)
INVENTOR(S) Jing Li (San Jose, California);  Kevin Kailin Du (San Jose, California)
ABSTRACT Highly accurate oxygen sensors made of graphene and titanium dioxide hybrid material are provided. With UV illumination, the disclosed sensors are capable of detecting O2 gas at room temperature and ambient pressure. The sensors are able to detect oxygen at concentrations ranging from about 0.2% to about 10% by volume under 365 nm UV light, and at concentrations ranging from 0.4% to 20% by volume under short wave UV light. The disclosed sensors have fast response and recovery times and can also be used to detect ozone.
FILED Wednesday, December 30, 2020
APPL NO 17/138806
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/3504 (20130101) Original (OR) Class
G01N 33/0039 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796469 Weisberger et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Joshua M. Weisberger (Newport News, Virginia);  Brett F. Bathel (Yorktown, Virginia)
ABSTRACT A real-time reference free background oriented schlieren system is provided. One embodiment includes a display device capable of generating an image pattern projected onto a retroreflective background. A beam splitter is used to transmit a portion of the projected image pattern towards a reference image sensor and another portion of the image pattern towards the retroreflective background and past a density object. The retroreflective background reflects the projected pattern back through the beam splitter and onto a signal imaging sensor. Collected data from the reference image sensor and the signal image sensor may be processed in real-time. The image pattern may be altered as necessary without requiring a new reference image, reducing the amount of time required to set up and adjust the system. A display device may be capable of switching between a schlieren visualization capability to a shadowgraph system allowing for the use of two different imaging techniques.
FILED Thursday, April 21, 2022
APPL NO 17/725693
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/2513 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/455 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796510 Kolb et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) South Dakota Board of Regents (Pierre, South Dakota)
ASSIGNEE(S) SOUTH DAKOTA BOARD OF REGENTS (Pierre, South Dakota)
INVENTOR(S) Lowell Kolb (Rapid City, South Dakota);  Charles Tolle (Rapid City, South Dakota);  Nathan Williams (Rapid City, South Dakota);  Jason Ash (Rapid City, South Dakota)
ABSTRACT A system for determining gas characteristics at high altitudes in embodiments of the present invention may have one or more of the following features: (a) a high-altitude balloon having one or more of the following features: (a) a balloon, (b) a balloonsat operably coupled to the balloon, (c) an air path chamber wherein gas at a high altitude can occupy the air path chamber, (d) a first speaker located on a substrate within the air path chamber, wherein the first speaker takes an electrical signal input and creates a first sound wave, and (e) a second speaker located on the substrate facing opposite of the first speaker located outside of the air path chamber, wherein the second speaker takes the electrical signal and creates a second sound wave.
FILED Friday, April 30, 2021
APPL NO 17/246093
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/024 (20130101)
G01N 29/036 (20130101) Original (OR) Class
G01N 29/222 (20130101)
G01N 29/2437 (20130101)
G01N 2291/011 (20130101)
G01N 2291/014 (20130101)
G01N 2291/021 (20130101)
G01N 2291/102 (20130101)
G01N 2291/02881 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11793174 Abban et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Samuel K. Abban (Laurel, Maryland);  Irving Smith (Glenleg, Maryland);  Francisco Posada-Florez (Laurel, Maryland)
ABSTRACT The bee washing system washes worker bees and filters out varroa mites so that a beekeeper/operator can estimate the number of infected bees in a hive. The system includes a bee containment section with a coarse mesh filter, and a wash material section with a fine mesh filter. The system is structured so that when the bee containment section is loaded with bees, and the wash material section is loaded with wash material, an operator washes the bees by shaking the system. When the wash is complete, the operator detaches the wash material section from the system and counts the mites present on the fine mesh filter.
FILED Friday, August 21, 2020
APPL NO 16/999161
ART UNIT 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 13/001 (20130101)
A01K 51/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793829 Palli et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Department of Agriculture (USDA)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Subba Reddy Palli (Lexington, Kentucky);  Ramesh Dhandapani (Lexington, Kentucky)
ABSTRACT The present invention relates to a polyplex composition for modulating expression of a gene-of-interest in an insect comprising: a crosslinker, a cation, and a molecule for initiating RNA interference (RNAi). The present invention further relates to polyplex compositions for modulating genes of interest in Aedes aegypti. The present invention further relates to methods of modulating a gene-of-interest in an insect, comprising: administering to an insect a polyplex composition for modulating expression of a gene-of-interest in an insect comprising: a crosslinker, a cation, and a molecule for initiating RNA interference (RNAi).
FILED Friday, August 28, 2020
APPL NO 17/006588
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/08 (20130101)
A61K 9/0053 (20130101)
A61K 31/713 (20130101) Original (OR) Class
A61K 47/32 (20130101)
A61K 47/6937 (20170801)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793870 De Los Santos et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia);  CODAGENIX INC. (Farmingdale, New York)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia);  Codagenix Inc. (Farmingdale, New York)
INVENTOR(S) Teresa B. De Los Santos (Miller Place, New York);  Aida E. Rieder (Westbrook, Connecticut);  Fayna C. Diaz-San Segundo (Blue Point, New York);  Anna Kloc (Guilford, Connecticut);  John R. Coleman (Blauvelt, New York);  Steffen Mueller (Kings Point, New York);  Gisselle N. Medina (Sound Beach, New York)
ABSTRACT The present disclosure describes deoptimized foot and mouth viruses and their use for prophylactic and therapeutic treatment of mammalian subjects. The recombinant viruses provided herein include alterations in several genomic regions as well as Differentiating Infected from Vaccinated Animals (DIVA) markers.
FILED Wednesday, May 26, 2021
APPL NO 17/330545
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/135 (20130101) Original (OR) Class
A61K 2039/552 (20130101)
A61K 2039/5254 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/32121 (20130101)
C12N 2770/32134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795115 Cai et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Zhiyong Cai (Madison, Wisconsin);  Qiangu Yan (Madison, Wisconsin)
ABSTRACT Methods of forming a carbon fiber reinforced carbon foam are provided. Such a method may comprise heating a porous body composed of a solid material comprising covalently bound carbon atoms and heteroatoms and having a surface defining pores distributed throughout the solid material, in the presence of an added source of gaseous hydrocarbons. The heating generates free radicals in the porous body from the heteroatoms and induces reactions between the free radicals and the gaseous hydrocarbons to form covalently bound carbon nanofibers extending from the surface of the solid material and a network of entangled carbon microfibers within the pores the porous body, thereby forming a carbon fiber reinforced carbon foam. Carbon fiber reinforced carbon foams and ballistic barriers incorporating the foams are also provided.
FILED Wednesday, February 08, 2023
APPL NO 18/107189
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/83 (20130101) Original (OR) Class
C04B 38/0022 (20130101)
C04B 2235/614 (20130101)
C04B 2235/5248 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795211 Sok et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) International AIDS Vaccine Initiative (New York, New York);  The Scripps Research Institute (La Jolla, California);  The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) International AIDS Vaccine Initiative (New York, New York);  The Scripps Research Institute (La Jolla, California);  THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S) Devin Sok (New York, New York);  Dennis R. Burton (La Jolla, California);  Vaughn V. Smider (La Jolla, California);  Ian Wilson (La Jolla, California);  Michael Criscitiello (College Station, Texas);  Waithaka Mwangi (College Station, Texas)
ABSTRACT The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab′)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody.
FILED Thursday, July 12, 2018
APPL NO 16/630768
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/162 (20130101)
C07K 16/1063 (20130101) Original (OR) Class
C07K 2317/10 (20130101)
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/33 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
C07K 2319/02 (20130101)
C07K 2319/31 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795458 Hunter et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Wayne B Hunter (Port Saint Lucie, Florida);  Salvador P. Lopez (Vero Beach, Florida)
ABSTRACT The present disclosure provides oligonucleotides and double-stranded RNAs (dsRNAs) targeting Hemipteran and Lepidopteran insect pests. Bantam-sequence targets are detailed and shown to be effective targets for RNAi induction utilizing multiple dsRNAs, antisense oligonucleotides, and modified dsRNAs (e.g., 2′-O-methylated and dsRNAs containing non-canonical nucleosides).
FILED Friday, December 17, 2021
APPL NO 17/554026
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/60 (20200101)

Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations
A01P 7/04 (20210801)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/321 (20130101)
C12N 2310/322 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11796548 Gladue et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Douglas P. Gladue (Guilford, Connecticut);  Ayushi Rai (Old Saybrook, Connecticut);  Manuel V. Borca (Westbrook, Connecticut)
ABSTRACT Methods are provided herein utilizing a stable cell line capable of efficient infection by African swine fever virus (ASFV) and also provides for the detection of the presence of virus in samples applied to the cells. Detection of the virus by means such as red blood cell rosetting is a surprising result given that the cell line is derived from African green monkeys. This cell line provides a marked improvement over the currently available testing strategies.
FILED Wednesday, April 21, 2021
APPL NO 17/236284
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/12031 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/80 (20130101) Original (OR) Class
G01N 2333/01 (20130101)
G01N 2800/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11794623 Schwartz et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) William Schwartz (Tucson, Arizona);  Amy Longshore (San Diego, California);  Erika Thoeny (Evanston, Illinois);  Sierra Raney (Blacksburg, Virginia);  Michael Nagy (Merrifield, Virginia);  Andrew Garcia (Tucson, Arizona)
ABSTRACT Vehicle shelf systems having indicators thereon for improving loading and delivery efficiency. Items are scanned for loading, and the indicators on the vehicle shelves identify where to place the item based on the sequence of the delivery point along the delivery route. A mobile computing device alerts a delivery carrier when the delivery vehicle is in proximity to a delivery point when an item is to be delivered.
FILED Wednesday, May 05, 2021
APPL NO 17/308432
ART UNIT 3655 — Material and Article Handling
CURRENT CPC
Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects
B60P 1/6409 (20130101)
B60P 1/6481 (20130101) Original (OR) Class
B60P 3/007 (20130101)

Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors
F21S 4/28 (20160101)

Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted
F21Y 2115/10 (20160801)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/04 (20130101)
G06Q 10/083 (20130101)
G06Q 10/087 (20130101)
G06Q 50/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797796 Stephen et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Victoria K. Stephen (Burke, Virginia);  Elke Reuning-Elliott (Rosslyn, Virginia)
ABSTRACT A multi-level distribution and tracking method is described. Processing equipment processes multi-level distribution items, the multi-level distribution items being associated with first, second, and third level entities. The multi-level distribution items include a computer readable code thereon. The processing equipment captures an image of the multi-level distribution item, reads a computer readable code associated with the first level entity, sender information for the second level entity, and destination address information for the third level entity. The distribution system delivers the item to the destination address for the third level entity. The processing equipment generates scan information based on the processing of the multi-level distribution item, and can send the tracking information to the first level entity.
FILED Monday, November 21, 2022
APPL NO 18/057346
ART UNIT 2876 — Optics
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/10 (20130101)
B07C 3/14 (20130101)

Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus
B42D 5/025 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/1413 (20130101)
G06K 7/1417 (20130101)
G06K 7/10861 (20130101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0833 (20130101)

Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus
G07B 2017/00475 (20130101)
G07B 2017/00588 (20130101)
G07B 2017/00596 (20130101)
G07B 2017/00709 (20130101)
G07B 2017/00717 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797913 Briggman et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) Chandra A. Briggman (Springfield, Virginia);  Jane Elizabeth Quenk (Washington, District of Columbia);  Timothy M. Moran (National Harbor, Maryland);  Thomas J. Foti (Annandale, Virginia);  Robert E. Dixon, Jr. (Washington, District of Columbia)
ABSTRACT A method, electronic device, and computer-readable storage medium for delivering supplemental physical and/or electronic content in association with a physical delivery item. Various embodiments include operations for receiving tracking data regarding a delivery item, determining, based on the tracking data, whether supplemental content is associated with the delivery item, and automatically scheduling delivery of the supplemental content when supplemental content is associated with the delivery item. Others embodiments include operations for obtaining tracking data regarding a delivery item; identifying, based on the tracking data, supplemental content associated with the delivery item; generating an electronic command to schedule delivery of the supplemental content at a delivery point of a user, the scheduled delivery being associated with a corresponding delivery date; and generating an electronic command to present, within a user interface, at least one of the electronic items of supplemental content to the user on the corresponding delivery date.
FILED Thursday, July 07, 2022
APPL NO 17/859166
ART UNIT 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)
G06Q 10/083 (20130101)
G06Q 10/0833 (20130101) Original (OR) Class
G06Q 10/1093 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 51/42 (20220501)
H04L 51/214 (20220501)
H04L 51/234 (20220501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797917 Amato
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) Michael J. Amato (Ocean Isle Beach, North Carolina)
ABSTRACT Systems and methods for enhancing digitally informed delivery of delivery items, such as mail or packages. A delivery item has an associated digital resource(s), such as electronic text, a digital file, an image, a web page(s), or the like. The delivery item includes an indicia, such as a bar code, that provides access to, or references, the digital resource. When the delivery item is processed during transit from the sender to the recipient of the delivery item, the indicia is read, and the associated digital resource is identified therefrom. The delivery service transmits, to the recipient, an electronic notification indicating that the delivery item is enroute to the recipient and also indicating the associated digital resource. The recipient can then access the digital resource, e.g., the custom text, files, images or web pages associated with the delivery item.
FILED Friday, October 07, 2022
APPL NO 17/961660
ART UNIT 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Electric Digital Data Processing
G06F 16/955 (20190101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0838 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 1/00222 (20130101)
H04N 1/32128 (20130101)
H04N 1/32144 (20130101)

Wireless Communication Networks
H04W 4/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US D1002989 Tartal
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) William A. Tartal (Baltimore, Maryland)
ABSTRACT
FILED Tuesday, March 07, 2023
APPL NO 29/872158
ART UNIT 2926 — Design
CURRENT CPC
Miscellaneous
D99/29
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11793794 Abdallah et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut);  The United States of America as represented by the Department of Veteran Affairs (Washington, District of Columbia)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Chadi Abdallah (New Haven, Connecticut);  John Krystal (New Haven, Connecticut);  Ronald Duman (New Haven, Connecticut);  Gerard Sanacora (New Haven, Connecticut)
ABSTRACT The present invention provides compositions and methods for treating diseases or disorders using a therapeutically effective amount of a rapid-acting antidepressant (RAAD) and a therapeutically effective amount of a mTOR inhibitor and/or immunosuppressant. In certain embodiments, the RAAD and the mTOR inhibitor and/or immunosuppressant are part of a single pharmaceutical composition.
FILED Tuesday, October 25, 2022
APPL NO 18/049589
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/08 (20130101)
A61K 9/0053 (20130101)
A61K 31/135 (20130101)
A61K 31/436 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/24 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11793860 Rome et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Leonard H. Rome (Tarzana, California);  Valerie Ann Kickhoefer (Sherman Oaks, California);  Steven M. Dubinett (Los Angeles, California);  Sherven Sharma (Oakland, California);  Upendra K. Kar (Oakland, California)
ABSTRACT The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
FILED Wednesday, August 12, 2020
APPL NO 16/991780
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)
A61K 38/00 (20130101)
A61K 38/45 (20130101)
A61K 38/195 (20130101) Original (OR) Class
A61K 47/6921 (20170801)
A61K 48/00 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 14/47 (20130101)
C07K 14/521 (20130101)
C07K 2319/00 (20130101)
C07K 2319/01 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 9/96 (20130101)
C12N 9/1077 (20130101)
C12N 15/86 (20130101)

Enzymes
C12Y 204/0203 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/535 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11798179 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Eye Institute (NEI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Jacob Antunes (Cincinnati, Ohio);  Zhouping Wei (Cleveland, Ohio);  Pallavi Tiwari (Wexford, Pennsylvania);  Satish E. Viswanath (Pepper Pike, Ohio);  Charlems Alvarez Jimenez (Bogotá, Colombia)
ABSTRACT The present disclosure, in some embodiments, relates to a non-transitory computer-readable medium storing computer-executable instructions. The computer readable medium is configured to cause a processor to access an image volume of a rectum comprising a rectal tumor. A forward mapping is generated based on non-rigidly registering a healthy rectal atlas to the image volume. The forward mapping is inverted to generate an inverse mapping from the image volume to the healthy rectal atlas. Based on the inverse mapping, a plurality of deformation vectors, associated with a deformation within a rectal wall of the rectum, are determined. Magnitude based deformation features and orientation based deformation features are computed from the plurality of deformation vectors. One or more of the magnitude based deformation features and one or more of the orientation based deformation features are utilized to determine a response of a patient to a chemoradiation treatment.
FILED Wednesday, September 22, 2021
APPL NO 17/481625
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/33 (20170101) Original (OR) Class
G06T 7/38 (20170101)
G06T 2207/10088 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
G16H 50/70 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11794420 Huang et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Luna Labs USA, LLC (Charlottesville, Virginia)
ASSIGNEE(S) LUNA LABS USA, LLC (Charlottesvile, Virginia)
INVENTOR(S) Jianhua Huang (Blacksburg, Virginia);  Daniel Robert Metrey (Blacksburg, Virginia)
ABSTRACT Advanced single vacuum bag (ASVB) fabrication methods and assemblies are provided to manufacture and repair polymer composites whereby a rigid check plate is mounted over an uncured laminate by a thermally collapsible check plate stand. The check plate stand thereby maintains a gap between the check plate and the uncured laminate during first stage processing conditions, yet is capable of thermally collapsing during subsequent second stage processing conditions to thereby allow the check plate to fall into compressive contact with the uncured laminate After the check plate collapses onto the uncured laminate, the compressive force of the check plate will be transferred to the laminate to consolidate the laminate as desired and thereby form an at least partially cured polymer composite structure of high quality.
FILED Monday, June 01, 2020
APPL NO 17/616094
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/342 (20130101) Original (OR) Class
B29C 70/541 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2063/00 (20130101)
B29K 2307/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11795459 Place et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) miRecule, Inc. (Gaithersburg, Maryland)
ASSIGNEE(S) MIRECULE, INC. (Gaithersburg, Maryland)
INVENTOR(S) Robert Place (Gaithersburg, Maryland);  Anthony Saleh (Gaithersburg, Maryland);  Tishan Williams (Gaithersburg, Maryland)
ABSTRACT Disclosed herein are engineered oligonucleotides for selective inhibition of polypeptide expression and activity. Also disclosed herein are methods of selectively inhibiting polypeptide expression and activity contacting an engineered oligonucleotide with a polynucleotide encoding the polypeptide.
FILED Friday, March 11, 2022
APPL NO 17/692630
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 47/549 (20170801)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/33 (20130101)
C12N 2310/141 (20130101)
C12N 2310/316 (20130101)
C12N 2310/321 (20130101)
C12N 2310/322 (20130101)
C12N 2310/351 (20130101)
C12N 2310/531 (20130101)
C12N 2310/3521 (20130101)
C12N 2320/31 (20130101)
C12N 2320/32 (20130101)
C12N 2320/35 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797873 King et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Atom Computing Inc. (Berkeley, California)
ASSIGNEE(S) Atom Computing Inc. (Berkeley, California)
INVENTOR(S) Jonathan King (Berkeley, California);  Benjamin Bloom (Berkeley, California);  Brian Lester (Berkeley, California)
ABSTRACT The present disclosure provides methods and systems for performing non-classical computations. The methods and systems generally use a plurality of spatially distinct optical trapping sites to trap a plurality of atoms, one or more electromagnetic delivery units to apply electromagnetic energy to one or more atoms of the plurality to induce the atoms to adopt one or more superposition states of a first atomic state and a second atomic state, one or more entanglement units to quantum mechanically entangle at least a subset of the one or more atoms in the one or more superposition states with at least another atom of the plurality, and one or more readout optical units to perform measurements of the superposition states to obtain the non-classical computation.
FILED Wednesday, January 06, 2021
APPL NO 17/143030
ART UNIT 2872 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/33 (20130101)

Optical Computing Devices;
G06E 3/00 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11795191 Ju et al.
FUNDED BY
Department of Commerce (DOC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Shiv Kumar (Belle Mead, New Jersey);  Chuanjuan Tao (New York, New York);  Minchen Chien (Tenafly, New Jersey);  James J. Russo (New York, New York);  John J. Kasianowicz (Darnestown, Maryland);  Joseph W. F. Robertson (Washington, District of Columbia)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York);  GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Shiv Kumar (Belle Mead, New Jersey);  Chuanjuan Tao (New York, New York);  Minchen Chien (Tenafly, New Jersey);  James J. Russo (New York, New York);  John J. Kasianowicz (Darnestown, Maryland);  Joseph W. F. Robertson (Washington, District of Columbia)
ABSTRACT This disclosure provides systems and methods for sequencing nucleic acids using nucleotide analogues and translocation of tags from incorporated nucleotide analogues through a nanopore. In aspects, this disclosure is related to composition, method, and system for sequencing a nucleic acid using tag molecules and detection of translocation through a nanopore of tags released from incorporation of the molecule.
FILED Monday, April 01, 2019
APPL NO 16/371646
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/00 (20130101) Original (OR) Class
C07H 19/06 (20130101)
C07H 19/16 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/42 (20130101)
C12Q 1/48 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6883 (20130101)
C12Q 2521/525 (20130101)
C12Q 2521/525 (20130101)
C12Q 2521/543 (20130101)
C12Q 2521/543 (20130101)
C12Q 2535/107 (20130101)
C12Q 2537/157 (20130101)
C12Q 2565/631 (20130101)
C12Q 2565/631 (20130101)
C12Q 2565/631 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/48721 (20130101)
G01N 2333/9125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11799673 Ganji et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida);  TECHNISCHE UNIVERSITAET BERLIN (Berlin, Germany)
INVENTOR(S) Fatemeh Ganji (Gainesville, Florida);  Shahin Tajik (Gainesville, Florida);  Jean-Pierre Seifert (Werder Havel, Germany);  Domenic Forte (Gainesville, Florida);  Mark M. Tehranipoor (Gainesville, Florida)
ABSTRACT Combined physical unclonable function (PUFs); methods, apparatuses, systems, and computer program products for enrolling combined PUFs; and methods, apparatuses, systems, and computer program products for authenticating a device physically associated with a combined PUF are described. In an example embodiment, a combined PUF includes a plurality of PUFs and one or more logic gates. Each PUF includes a plurality of stages and an arbiter configured to generate a single PUF response based on response portions generated by the plurality of stages. The one or more logic gates are configured to combine the single PUF response for each of the plurality of PUFs in accordance with a combination function to provide a combined response.
FILED Tuesday, April 07, 2020
APPL NO 16/841873
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 19/0963 (20130101)
H03K 19/1737 (20130101)
H03K 19/17748 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/002 (20130101)
H04L 9/0866 (20130101)
H04L 9/3271 (20130101)
H04L 9/3278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11794977 Steed
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Darren Jay Steed (Egg Harbor Township, New Jersey)
ABSTRACT The present application is directed to a packaging for a powdered explosive-detection training aid which may include first and second opposing flexible sheets heat sealed together along less than a periphery thereof and defining a storage compartment therebetween, wherein an unsealed portion of the periphery defines an opening to the storage compartment, wherein at least a portion of the first opposing flexible sheet is a semipermeable material permeable to a vapor emitted from the powdered explosive-detection training aid, with the second opposing flexible sheet being impermeable to the powdered explosive-detection training aid vapor; and a sealing member, wherein the sealing member is secured to the first opposing flexible sheet and, in a closing position, covers the semipermeable portion of the first opposing flexible sheet.
FILED Thursday, December 23, 2021
APPL NO 17/560513
ART UNIT 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 15/02 (20130101)

Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages
B65D 33/01 (20130101)
B65D 75/30 (20130101) Original (OR) Class
B65D 85/70 (20130101)
B65D 2565/388 (20130101)

Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 11/132 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 8/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11800352 Boyd et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Daniel A Boyd (Arlington, Virginia);  Kelli L. Biegger (Fort Worth, Texas);  Chang Ellison (Arlington, Virginia);  Brandon P. Gutierrez (Johns Creek, Georgia);  Jason Lim (Alexandria, Virginia);  William Washington (North Potomac, Maryland)
ABSTRACT A vehicle information remote retrieval method includes an emergency personnel or first responder vehicle (FRV) establishing a vehicle connection between an infotainment system of a vehicle and the FRV. The FRV sends a vehicle information request to the infotainment system of the vehicle, via the vehicle connection, seeking release of vehicle information. The FRV obtains authentication of the vehicle information received in response to the vehicle information request. The FRV determines occupant status based on the vehicle information. The FRV communicates the passenger status to a first responder.
FILED Monday, January 23, 2023
APPL NO 18/100040
ART UNIT 2433 — Cryptography and Security
CURRENT CPC
Systems for Controlling or Regulating Non-electric Variables
G05D 1/00 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/10 (20130101)

Wireless Communication Networks
H04W 4/46 (20180201)
H04W 12/02 (20130101)
H04W 12/04 (20130101) Original (OR) Class
H04W 12/08 (20130101)
H04W 12/033 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Central Intelligence Agency (CIA) 

US 11794928 Beck et al.
FUNDED BY
Central Intelligence Agency (CIA)
APPLICANT(S) Rocket Lab USA, Inc. (Huntington Beach, California)
ASSIGNEE(S) Rocket Lab USA, Inc. (Long Beach, California)
INVENTOR(S) Peter Beck (Auckland, New Zealand);  Peter Barlow (Huntington Beach, California);  David Yoon (La Crescenta, California);  Ben Malcolm (Auckland, New Zealand)
ABSTRACT A satellite dispenser and method of using same are disclosed. In various embodiments, a satellite dispenser as disclosed herein includes a dispenser body defining an interior cavity to accommodate a payload; and a plurality of externally adjustable restraints positioned within the interior cavity and configured to be extended further into the interior cavity by actuation of a manual interface external to the interior cavity.
FILED Wednesday, June 09, 2021
APPL NO 17/343614
ART UNIT RD00 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Cutting; Details Common to Machines for Perforating, Punching, Cutting-out, Stamping-out or Severing
B26D 5/12 (20130101)

Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects
B60P 7/16 (20130101)
B60P 7/135 (20130101)

Cosmonautics; Vehicles or Equipment Therefor
B64G 1/007 (20130101)
B64G 1/22 (20130101) Original (OR) Class
B64G 1/222 (20130101)
B64G 1/645 (20130101)

Hinges or Suspension Devices for Doors, Windows or Wings
E05D 3/08 (20130101)
E05D 7/00 (20130101)

Devices for Moving Wings into Open or Closed Position; Checks for Wings; Wing Fittings Not Otherwise Provided For, Concerned With the Functioning of the Wing
E05F 1/105 (20130101)
E05F 3/20 (20130101)

Indexing Scheme Relating to Hinges or Other Suspension Devices for Doors, Windows or Wings and Devices for Moving Wings into Open or Closed Position, Checks for Wings and Wing Fittings Not Otherwise Provided For, Concerned With the Functioning of the Wing
E05Y 2201/216 (20130101)
E05Y 2201/426 (20130101)
E05Y 2900/50 (20130101)
E05Y 2900/531 (20130101)

Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings
F16C 29/005 (20130101)
F16C 33/24 (20130101)
F16C 2208/82 (20130101)
F16C 2223/32 (20130101)
F16C 2326/47 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 3/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 11795109 Fatmehsari et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Highway Administration (FHWA)
APPLICANT(S) NUtech Ventures (Lincoln, Nebraska)
ASSIGNEE(S) NUtech Ventures (Lincoln, Nebraska)
INVENTOR(S) Hamzeh Haghshenas Fatmehsari (Lincoln, Nebraska);  Robert Rea (Ashland, Nebraska)
ABSTRACT An asphalt pavement modification system and method for improving aging resistance of asphalt pavement and a method of manufacturing reclaimed asphalt pavement. The asphalt pavement modification system and method include using one or more antioxidants and one or more recycling agents in a blended binder to provide improved short term and long term performance of the asphalt pavement. The method of manufacturing reclaimed asphalt pavement includes mixing at least one antioxidant with at least one recycling agent to form a binder that constitutes a portion of the reclaimed asphalt pavement. One of the antioxidants may be zinc diethyldithiocarbamate.
FILED Friday, July 09, 2021
APPL NO 17/371478
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 26/003 (20130101) Original (OR) Class
C04B 26/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11799799 Blumrich et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) NVIDIA Corp. (Santa Clara, California)
ASSIGNEE(S) NVIDIA Corp. (Santa Clara, California)
INVENTOR(S) Matthias Augustin Blumrich (Ridgefield, Connecticut);  Nan Jiang (Acton, Massachusetts);  Larry Robert Dennison (Mendon, Massachusetts)
ABSTRACT A switch architecture enables ports to stash packets in unused buffers on other ports, exploiting excess internal bandwidth that may exist, for example, in a tiled switch. This architecture leverages unused port buffer memory to improve features such as congestion handling and error recovery.
FILED Friday, July 16, 2021
APPL NO 17/377943
ART UNIT 2419 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 49/70 (20130101)
H04L 49/101 (20130101) Original (OR) Class
H04L 49/254 (20130101)
H04L 49/3036 (20130101)
H04L 49/9047 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11794254 Hoy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Non-Profit Organization (NPO)
National Center for Manufacturing Sciences Inc. (NCMS)
APPLICANT(S) 3D Systems, Inc. (Rock Hill, South Carolina)
ASSIGNEE(S) 3D SYSTEMS, INC. (Rock Hill, South Carolina)
INVENTOR(S) Ahren Michael Hoy (Charlotte, North Carolina);  Turner Ashby Cathey (Rock Hill, South Carolina);  Alexander J Geyling (Fort Mill, South Carolina)
ABSTRACT An additive manufacturing system for producing a three-dimensional article includes a print engine, a post-fabrication powder removal apparatus, a transport mechanism, and a controller. The post fabrication removal apparatus includes a rotary frame defining an internal receptacle cavity, a plurality of clamps coupled to a corresponding plurality of actuators, a clamping plate coupled to a lift apparatus, and an agitation device mounted to the clamping plate. The controller is configured to perform the following steps: (1) Operate the transport mechanism to transport the build box to the internal receptacle cavity. (2) Operate the plurality of actuators to engage the build box with the plurality of clamps to secure the build box to the rotary frame. (3) Operate the rotary frame to rotate the build box until unfused powder begins to exit the build box. (4) Operate the agitation device to facilitate pouring of the unfused powder from the build box.
FILED Friday, February 03, 2023
APPL NO 18/163956
ART UNIT 2853 — Printing/Measuring and Testing
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/28 (20210101)
B22F 10/68 (20210101) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 40/20 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11796176 Vallejo Ruiz et al.
FUNDED BY
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Ernesto Andres Vallejo Ruiz (Cincinnati, Ohio);  Aaron Michael Dziech (Crittenden, Kentucky);  Jonathon Eli Farmer (Newport, Kentucky)
ABSTRACT A combustor assembly for a gas turbine engine defining a radial direction and a circumferential direction includes a liner assembly at least partially defining a combustion chamber and including at least one liner extending between a downstream end and an upstream end, the downstream end of the at least one liner defining a radial opening and an interface surface extending along the circumferential direction and along the radial direction; and a seal member including a body, a flange, and a radial element, the body defining a body surface extending along the radial direction and positioned adjacent the interface surface of the at least one liner, the flange extending forward from the body, and the radial element coupled to the flange and extending into the radial opening defined by the at least one liner.
FILED Wednesday, December 22, 2021
APPL NO 17/559686
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 9/023 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/007 (20130101)
F23R 3/60 (20130101) Original (OR) Class
F23R 2900/00012 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11797198 Roberts
FUNDED BY
APPLICANT(S) Micron Technology, Inc. (Boise, Idaho)
ASSIGNEE(S) Micron Technology, Inc. (Boise, Idaho)
INVENTOR(S) David Andrew Roberts (Wellesley, Massachusetts)
ABSTRACT Various embodiments provide for one or more processor instructions and memory instructions that enable a memory sub-system to copy, move, or swap data across (e.g., between) different memory tiers of the memory sub-system, where each of the memory tiers is associated with different memory locations (e.g., different physical memory locations) on one or more memory devices of the memory sub-system.
FILED Friday, April 23, 2021
APPL NO 17/238791
ART UNIT 2136 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 3/0605 (20130101)
G06F 3/0631 (20130101) Original (OR) Class
G06F 3/0647 (20130101)
G06F 3/0653 (20130101)
G06F 3/0659 (20130101)
G06F 3/0679 (20130101)
G06F 12/0238 (20130101)
G06F 12/0292 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 24, 2023.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20231024.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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