FedInvent™ Patents

Patent Details for Tuesday, November 14, 2023 

This page was updated on Tuesday, November 14, 2023 at 04:45 PM GMT

Department of Health and Human Services (HHS) 

US 11812966 Dreilinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) NeuraMedica Inc. (Oregon City, Oregon)
ASSIGNEE(S) NeuraMedica Inc. (Oregon City, Oregon)
INVENTOR(S) Rachel Dreilinger (Beavercreek, Oregon);  Neil Roundy (Eugene, Oregon);  Mariah Knight (Cornelius, Oregon);  Sandra Baker (Tigard, Oregon)
ABSTRACT A medical device forming method, an applier for manipulating clips, and a cartridge for holding clips are disclosed herein.
FILED Friday, April 24, 2020
APPL NO 16/858546
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/083 (20130101) Original (OR) Class
A61B 17/1222 (20130101)
A61B 2017/0488 (20130101)
A61B 2017/00584 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813037 Melodia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Research Foundation for The State University of New York (Amherst, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Amherst, New York)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Giuseppe Enrico Santagati (Cambridge, Massachusetts);  Laura Galluccio (Trecastagni, Italy);  Sergio Palazzo (San Giovanni la Punta, Italy)
ABSTRACT Methods and devices for transmitting and receiving data through biological tissue using ultrasonic pulses are described. Methods of the present invention may set an initial time-hopping frame length and an initial spreading code length for data transmission. A request-to-transmit may be sent from a transmitter over a control channel at the initial frame and code length. The receiver may respond to the transmitter with a clear-to-transmit packet having feedback information. The feedback information can be used to improve a forward time-hopping frame length and a forward spreading code length. Embodiments of the invention may involve a body area network or body surface network comprising a plurality of implanted sensor nodes operating according to the disclosed invention.
FILED Monday, January 25, 2021
APPL NO 17/157251
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0015 (20130101)
A61B 5/021 (20130101)
A61B 5/0024 (20130101)
A61B 5/024 (20130101)
A61B 5/026 (20130101)
A61B 5/0028 (20130101) Original (OR) Class
A61B 5/0031 (20130101)
A61B 5/0816 (20130101)
A61B 5/14532 (20130101)
A61B 5/14542 (20130101)

Transmission Systems for Measured Values, Control or Similar Signals
G08C 23/02 (20130101)

Transmission
H04B 1/71635 (20130101)
H04B 2001/6908 (20130101)

Selecting
H04Q 9/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813047 Meyer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Craig H. Meyer (Charlottesville, Virginia);  Anudeep Konda (Los Angeles, California);  Christopher M. Kramer (Charlottesville, Virginia);  Xue Feng (Charlottesville, Virginia)
ABSTRACT In one aspect the disclosed technology relates to embodiments of a method which, includes acquiring magnetic resonance imaging data, for a plurality of images, of the heart of a subject. The method also includes segmenting, using cascaded convolutional neural networks (CNN), respective portions of the images corresponding to respective epicardium layers and endocardium layers for a left ventricle (LV) and a right ventricle (RV) of the heart. The segmenting is used for extracting biomarker data from segmented portions of the images and, in one embodiment, assessing hypertrophic cardiomyopathy from the biomarker data. The method further includes segmenting processes for T1 MRI data and LGE MRI data.
FILED Tuesday, June 01, 2021
APPL NO 17/335518
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/029 (20130101)
A61B 5/0263 (20130101) Original (OR) Class
A61B 5/1071 (20130101)
A61B 5/1075 (20130101)
A61B 5/7267 (20130101)

Electric Digital Data Processing
G06F 18/211 (20230101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101)
G06T 7/13 (20170101)
G06T 7/62 (20170101)
G06T 7/70 (20170101)
G06T 2207/10088 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30048 (20130101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101)
G06V 10/764 (20220101)
G06V 2201/031 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813054 Dawson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Geospatial Intelligence Agency (NGA)
National Science Foundation (NSF)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Geraldine Dawson (Durham, North Carolina);  Guillermo Sapiro (Durham, North Carolina);  Jordan Hashemi (Durham, North Carolina)
ABSTRACT The subject matter described herein includes methods, systems, and computer readable media for conducting an automatic assessment of postural control of a subject. According to one aspect, a method occurs at a computing platform including a processor and memory. The method includes displaying a stimulus to which a subject responds, capturing facial image data of the subject, analyzing the facial image data to determine a frequency of head displacement information associated with the subject, using the head displacement information to derive postural control assessment data, and determining that the postural control assessment data is indicative of a neurodevelopmental or neuropsychiatric disorder associated with the subject.
FILED Friday, November 08, 2019
APPL NO 16/678828
ART UNIT 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1116 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 3/012 (20130101)
G06F 3/017 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/70 (20170101)
G06T 2207/30201 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813056 Singamaneni et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Srikanth Singamaneni (St. Louis, Missouri);  Zheyu Wang (St. Louis, Missouri);  Jingyi Luan (St. Louis, Missouri)
ABSTRACT The present disclosure is directed to microneedle patches for direct sampling and ultrasensitive detection of protein biomarkers in dermal interstitial fluids. The microneedle patches are comprised of polymers with high protein absorption capability (e.g. polystyrene) and are modified with capture biorecognition elements that are specific to target analytes in the interstitial fluid (ISF). Systems and methods are further provided for detection of a target ISF analyte obtained by in vivo sampling of the ISF using a microneedle patch.
FILED Thursday, July 30, 2020
APPL NO 16/943157
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/14514 (20130101) Original (OR) Class

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0021 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0015 (20130101)
A61M 2037/0061 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5306 (20130101)
G01N 33/6869 (20130101)
G01N 33/54386 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813100 Tichauer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) The Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Kenneth M. Tichauer (Chicago, Illinois);  Scott C. Davis (Woodville, New Hampshire);  Brian William Pogue (Hanover, New Hampshire)
ABSTRACT An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images.
FILED Monday, January 09, 2017
APPL NO 15/402077
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 6/032 (20130101)
A61B 6/037 (20130101)
A61B 6/481 (20130101) Original (OR) Class
A61B 6/4417 (20130101)
A61B 6/5235 (20130101)
A61B 6/5247 (20130101)

Image Data Processing or Generation, in General
G06T 5/50 (20130101)
G06T 2207/10081 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/10104 (20130101)
G06T 2207/10108 (20130101)
G06T 2207/20224 (20130101)
G06T 2207/30024 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813105 Dejongh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY (Dekalb, Illinois);  PROTONVDA LLC (Naperville, Illinois)
ASSIGNEE(S) BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY (Dekalb, Illinois);  PROTONVDA LLC (Naperville, Illinois)
INVENTOR(S) Don F. Dejongh (Batavia, Illinois);  Ethan A. Dejongh (Batavia, Illinois);  Kirk Duffin (Batavia, Illinois);  Nicholas Karonis (Batavia, Illinois);  Caesar Ordoñez (Batavia, Illinois);  John Winans (Batavia, Illinois)
ABSTRACT A computer-implemented system and method for generating a medical image is provided. In some embodiments, the medical image is generated by determining a location and an alignment for a first tracking detector with respect to a particle beam system. The direction of a beam generated from the particle beam system is determined. A first position of a first particle from a detected particle hit on the first tracking detector is also determined. A determination is made as to a first residual range of the first particle from a detected particle hit on a residual range detector. The system reconstructs a path for the first particle based on the location, the alignment, the first position, and the first residual range of the first particle. The resulting medical image that is generated by the system is based on the reconstructed path for the first particle.
FILED Friday, January 15, 2021
APPL NO 17/149948
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/032 (20130101)
A61B 6/547 (20130101)
A61B 6/587 (20130101)
A61B 6/588 (20130101)
A61B 6/4071 (20130101)
A61B 6/4258 (20130101)
A61B 6/5205 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813168 Callcott et al.
FUNDED BY
Department of Health and Human Services (HHS)
Food and Drug Administration (FDA)
APPLICANT(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
ASSIGNEE(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
INVENTOR(S) Trent Gardner Callcott (Atlanta, Georgia);  Jonathan William Schwartz (Atlanta, Georgia);  David Nelson Ku (Atlanta, Georgia)
ABSTRACT Embodiments of an artificial meniscus are disclosed herein. An artificial meniscus includes at least one circumferential fiber bundle and the at least one non-circumferential fiber bundle embedded in a polymer material. The non-circumferential fiber bundles are fully encapsulated within the polymer material, and the circumferential fiber bundles extend out of anterior and posterior horns of the artificial meniscus to terminate in ends that are configured for fixation to bone. Methods of making and implanting artificial menisci are also disclosed herein. The methods of making include, but are not limited to, stepwise molding, layering, and curing of polymer material around the circumferential and non-circumferential fiber bundles. The methods of implanting include threading ends of the circumferential fiber bundles through first and second bone tunnels, then immobilizing the ends of the circumferential fiber bundles with respect to the bone of the subject.
FILED Friday, April 12, 2019
APPL NO 17/045886
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/3872 (20130101) Original (OR) Class
A61F 2/30942 (20130101)
A61F 2002/30009 (20130101)
A61F 2002/30957 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813235 Seyedsayamdost et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Mohammad R. Seyedsayamdost (Princeton, New Jersey);  Bethany K. Okada (San Diego, California);  Anran Li (Plainsboro, New Jersey)
ABSTRACT Disclosed are methods for using guanfacine, an analog or derivative of guanfacine, or a pharmaceutically acceptable salt thereof, to reduce the virulence of a bacterial pathogen. When treating a patient, the method generally involves administering to the patient a therapeutically effective dose of guanfacine, an analog or derivative of guanfacine, or a pharmaceutically acceptable salt thereof. An alternative method involves contacting the bacterial pathogen with guanfacine, an analog or derivative of guanfacine, or a pharmaceutically acceptable salt thereof.
FILED Friday, March 20, 2020
APPL NO 16/824968
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/155 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813258 Mohsen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Al-Walid A. Mohsen (Gibsonia, Pennsylvania);  Gerard Vockley (Pittsburgh, Pennsylvania)
ABSTRACT Methods of treating mitochondrial fatty acid β-oxidation and/or transport disorders arising from mutant proteins in the mitochondrial fatty acid β-oxidation and transport metabolic pathways in patients are provided. The methods modulate the mitochondrial fatty acid β-oxidation pathway at the last step so that the product of the mutant protein accumulates and stabilizes the mutant protein and/or the substrate(s)/product(s) of the down stream reactions accumulate and possibly bind to allosteric sites on the mutant protein to stabilize it. Trimetazidine pharmacodynamics function as such in the β-oxidation pathway. Further, a synergistic effect is observed where trimetazidine and PPARδ agonist combination enhanced enzyme activity and presence significantly more than either alone.
FILED Thursday, June 10, 2021
APPL NO 17/344084
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/426 (20130101)
A61K 31/426 (20130101)
A61K 31/495 (20130101)
A61K 31/495 (20130101)
A61K 31/496 (20130101) Original (OR) Class
A61K 38/45 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/08 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813264 Scarisbrick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Isobel A Scarisbrick (Rochester, Minnesota);  Hye-Sook Yoon (Rochester, Minnesota);  Kristen L. Drucker (Oronoco, Minnesota)
ABSTRACT Materials and methods for modulating protease activated receptor 1 (PAR1) activity to alter myelination are provided.
FILED Tuesday, November 16, 2021
APPL NO 17/528103
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101) Original (OR) Class
A61K 31/7105 (20130101)
A61K 35/12 (20130101)
A61K 35/30 (20130101)
A61K 48/00 (20130101)
A61K 48/0058 (20130101)
A61K 48/0066 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/00 (20130101)
C12N 15/63 (20130101)
C12N 15/85 (20130101)
C12N 2506/03 (20130101)
C12N 2506/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813268 Gavathiotis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Albert Einstein College of Medicine (Bronx, New York)
ASSIGNEE(S) Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S) Evripidis Gavathiotis (Roslyn, New York);  Richard N. Kitsis (New York, New York);  Nikolaos Biris (Lancaster, New York);  Emmanouil Zacharioudakis (Bronx, New York)
ABSTRACT Activators of mitofusins and their uses in treatment of diseases and disorders are disclosed.
FILED Tuesday, October 16, 2018
APPL NO 16/643986
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/42 (20130101)
A61K 31/165 (20130101)
A61K 31/167 (20130101)
A61K 31/277 (20130101)
A61K 31/341 (20130101)
A61K 31/351 (20130101)
A61K 31/402 (20130101)
A61K 31/415 (20130101)
A61K 31/429 (20130101)
A61K 31/437 (20130101)
A61K 31/506 (20130101)
A61K 31/519 (20130101)
A61K 31/551 (20130101) Original (OR) Class
A61K 31/4196 (20130101)
A61K 31/4245 (20130101)
A61K 31/4985 (20130101)
A61K 31/5025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813276 Davies
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Daryl Davies (Los Angeles, California)
ABSTRACT Provided herein are methods to improve transport or uptake of an avermectin compound in a cell or tissue expressing an efflux transporter P-glycoprotein (Pgp) by co-administering an effective amount of the avermectin compound and a Ppg inhibitor to the cell or tissue. The method also provides improved efficiency transport or uptake of an avermectin compound in the cell or tissue. The methods can be used therapeutically to treat Alcohol Use Disorder.
FILED Thursday, October 21, 2021
APPL NO 17/507507
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/365 (20130101)
A61K 31/4725 (20130101)
A61K 31/7048 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/32 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813277 Divakaruni et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Ajit Srinivas Divakaruni (Los Angeles, California);  Steven J. Bensinger (Sherman Oaks, California);  Anne Neville Murphy (Encitinas, California);  Wei Yuan Hsieh (Los Angeles, California)
ABSTRACT Methods and agents for modulating intracellular coenzyme A levels are described for therapeutic purposes. Increasing intracellular coenzyme A increases alternate macrophage activation resulting in suppression or resolution of an immune response for benefit in treating inflammatory diseases. Decreasing intracellular coenzyme A levels decreases alternate macrophage activation which is beneficial in treating NASH/NAFLD and various fibrotic diseases as well as reversing immune suppressing activity of tumor-associated immune cells such as macrophages for the treatment of cancer.
FILED Thursday, June 27, 2019
APPL NO 17/252962
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7064 (20130101) Original (OR) Class
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813284 Doxey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Novan, Inc. (Durham, North Carolina)
ASSIGNEE(S) Novan, Inc. (Durham, North Carolina)
INVENTOR(S) Ryan Doxey (Raleigh, North Carolina);  Jian Bao (Cary, North Carolina)
ABSTRACT The present invention generally relates to topical compositions and methods of using the same. A preferred topical pharmaceutical composition comprises a nitric oxide-releasing active pharmaceutical ingredient in admixture with a hydrophilic composition and a hydrophobic composition wherein the nitric oxide-releasing active pharmaceutical ingredient comprises a nitric oxide-releasing compound having a diazeniumdiolate functional group.
FILED Friday, August 08, 2014
APPL NO 14/910207
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 8/25 (20130101)
A61K 8/042 (20130101)
A61K 8/345 (20130101)
A61K 8/898 (20130101)
A61K 9/06 (20130101)
A61K 9/10 (20130101)
A61K 9/0014 (20130101)
A61K 9/107 (20130101)
A61K 33/00 (20130101) Original (OR) Class
A61K 47/02 (20130101)
A61K 47/10 (20130101)
A61K 47/12 (20130101)
A61K 47/14 (20130101)
A61K 47/32 (20130101)
A61K 47/38 (20130101)
A61K 47/44 (20130101)
A61K 47/52 (20170801)
A61K 47/59 (20170801)
A61K 2800/22 (20130101)

Specific Use of Cosmetics or Similar Toilet Preparations
A61Q 17/005 (20130101)
A61Q 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813289 Milgrom et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ADVANTAGE SILVER DENTAL ARREST, LLC (Salem, Oregon)
ASSIGNEE(S) ADVANTAGE SILVER DENTAL ARREST, LLC (Salem, Oregon)
INVENTOR(S) Peter M. Milgrom (Seattle, Washington);  Jong Seto (San Francisco, California)
ABSTRACT The invention provides compositions and methods that comprise encapsulated silver diamine fluoride or other antimicrobial materials for use in treatment of dental caries, for example.
FILED Friday, April 05, 2019
APPL NO 17/252963
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 9/501 (20130101)
A61K 9/5073 (20130101)
A61K 9/5089 (20130101)
A61K 33/38 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 47/02 (20130101)
A61K 47/16 (20130101)
A61K 47/32 (20130101)
A61K 47/34 (20130101)
A61K 47/46 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813298 Gromeier et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Matthias Gromeier (Durham, North Carolina);  John H. Sampson (Durham, North Carolina);  Darell D. Bigner (Mebane, North Carolina);  Annick Desjardins (Durham, North Carolina);  Henry S. Friedman (Durham, North Carolina)
ABSTRACT Human clinical use of a chimeric poliovirus construct has demonstrated excellent anti-tumor effect. The mechanism of action is believed to involve both viral oncolysis as well as immune recruitment, both of which lead to necrosis in the area of the tumor. No adverse effects have been observed.
FILED Tuesday, July 05, 2022
APPL NO 17/857534
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0085 (20130101)
A61K 35/768 (20130101) Original (OR) Class
A61K 41/00 (20130101)
A61K 45/06 (20130101)
A61K 51/081 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/32611 (20130101)
C12N 2770/32632 (20130101)
C12N 2770/32671 (20130101)
C12N 2770/32733 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813308 Hruska et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) CELGENE CORPORATION (Summit, New Jersey);  WASHINGTON UNIVERSITY (St. Louis, Missouri)
ASSIGNEE(S) Celgene Corporation (Missouri, Macau);  Washington University (St. Louis, Missouri)
INVENTOR(S) Keith Hruska (Creve Coeur, Missouri);  Yifu Fang (St. Louis, Missouri);  William Smith (Woodstock, New York);  Nianhang Chen (Basking Ridge, New Jersey)
ABSTRACT Provided herein are methods of treating diseases associated with vascular calcification and/or cardiovascular disease in a subject by using the level of a biomarker, in particular, snail homolog 1 (Snai1), phosphosmad2, phosphosmad3, urinary protein, dickkopf homolog 1 (Dkk1), collagen type 1 alpha 1 (Col1a1), activin (e.g., free activin), runt-related transcription factor 2 (Runx2), alkaline phosphatase (Alp), bone-specific alkaline phosphatase (BSAP), C-terminal type 1 collagen telopeptide (CTX), osterix, Klotho, alpha-smooth muscle actin (alpha-SMA), myocardin (MYOCD), activin receptor type 2A (ActRIIA), axis inhibition protein 2 (Axin2), and/or smooth muscle protein 22-alpha (Sm22-alpha), as an indicator(s) of responsiveness of the subject to the treatment, efficacy of the treatment, or appropriate dosage for the treatment with an activin type II receptor signaling inhibitor. Provided herein are methods of bone resorption in a subject by using the level of a biomarker, in particular, snail homolog 1 (Snai1), phosphosmad2, phosphosmad3, urinary protein, dickkopf homolog 1 (Dkk1), collagen type 1 alpha 1 (Col1a1), activin (e.g., free activin), runt-related transcription factor 2 (Runx2), alkaline phosphatase (Alp), bone-specific alkaline phosphatase (BSAP), c-terminal telopeptide (CTX), osterix, Klotho, alpha-smooth muscle actin (alpha-SMA), myocardin (MYOCD), activin receptor type 2A (ActRIIA), axis inhibition protein 2 (Axin2), and/or smooth muscle protein 22-alpha (Sm22-alpha), as an indicator(s) of responsiveness of the subject to the treatment, efficacy of the treatment, or appropriate dosage for the treatment with an activin type II receptor signaling inhibitor.
FILED Thursday, October 08, 2015
APPL NO 15/517782
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/179 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)
A61P 9/10 (20180101)
A61P 19/10 (20180101)

Peptides
C07K 14/71 (20130101)
C07K 2319/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813316 Uchida et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Naoya Uchida (Rockville, Maryland);  John F. Tisdale (Washington, District of Columbia)
ABSTRACT The invention is directed to a more efficient lentiviral vector comprising a nucleic acid sequence encoding a human β-globin protein or a human γ-globin protein, which is oriented from 5′ to 3′ relative to the lentiviral genome. The invention also provides a composition and method utilizing the lentiviral vector.
FILED Tuesday, December 17, 2019
APPL NO 16/717420
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/42 (20130101) Original (OR) Class
A61K 48/005 (20130101)

Peptides
C07K 14/805 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2740/16043 (20130101)
C12N 2830/008 (20130101)
C12N 2830/46 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813318 Russell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Washington through its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) UNIVERSITY OF WASHINGTON (Seattle, Washington)
INVENTOR(S) David W. Russell (Seattle, Washington);  Roli K. Hirata (Seattle, Washington)
ABSTRACT The invention provides isolated primate cells preferably human cells that comprise a genetically engineered disruption in a beta-2 microglobulin (B2M) gene, which results in deficiency in MHC class I expression and function. Also provided are the method of using the cells for transplantation and treating a disease condition.
FILED Wednesday, July 10, 2019
APPL NO 16/507589
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)
A61K 35/28 (20130101)
A61K 39/0005 (20130101) Original (OR) Class
A61K 2039/515 (20130101)

Peptides
C07K 14/70539 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2740/17043 (20130101)
C12N 2750/14143 (20130101)
C12N 2800/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813324 Morrison
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Trudy G Morrison (Northborough, Massachusetts)
ABSTRACT The invention provides methods for using virus-like particle (VLP) vaccines containing a stabilized pre-fusion respiratory syncytial virus (RSV) F protein to stimulate RSV neutralizing antibodies in pre-immune subjects. In one embodiment, the invention provides a method for immunizing a mammalian subject in need of immunizing against Respiratory Syncytial virus (RSV) infection, comprising, a) providing i) a pre-immune mammalian subject containing RSV neutralizing antibodies, ii) a first composition comprising recombinant chimeric Newcastle disease virus-like particles (ND VLPs), that contain a chimeric protein comprising, in N operable combination, 1) stabilized pre-fusion RSV F protein ectodomain, 2) transmembrane (TM) domain of NDV F protein, and 3) cytoplasmic (CT) domain of NDV F protein, and b) administering an immunologically effective amount of the first composition to the pre-immune subject to produce an immunized subject that comprises an increase in the level of the RSV neutralizing antibodies compared to the level of RSV neutralizing antibodies in the pre-immune subject. In one embodiment, the level of the RSV neutralizing antibodies in the pre-immune subject does not prevent RSV infection of the pre-immune subject.
FILED Tuesday, February 22, 2022
APPL NO 17/677399
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/17 (20130101) Original (OR) Class
A61K 2039/5256 (20130101)
A61K 2039/5258 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/18122 (20130101)
C12N 2760/18134 (20130101)
C12N 2760/18171 (20130101)
C12N 2760/18522 (20130101)
C12N 2760/18534 (20130101)
C12N 2760/18571 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813331 Khan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S) Atif J. Khan (Monroe, New Jersey);  Suzie Chen (Highland Park, New Jersey);  James S. Goydos (East Brunswick, New Jersey);  Bruce G. Haffty (Somerset, New Jersey)
ABSTRACT Disclosed is a method of treating a tumor in a patient, comprising (a) administering riluzole in an amount effective to sensitize the tumor cells to ionizing radiation, and (b) irradiating the tumor cells with ionizing radiation in a dose effective to reduce tumor cell growth. The method can further comprise administering an effective amount of one or more additional therapeutic agents.
FILED Wednesday, December 08, 2021
APPL NO 17/545559
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0038 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813333 Lai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina)
ASSIGNEE(S) THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina)
INVENTOR(S) Samuel Lai (Carrboro, North Carolina);  Morgan McSweeney (Cary, North Carolina)
ABSTRACT The present disclosure relates to methods of reducing accelerated blood clearance of at least one pegylated therapeutic composition in a subject suffering from a disease and in need of treatment. The methods involve administering at least one high molecular weight polyethylene glycol composition to a subject suffering from a disease. The administration of at least one high molecular weight polyethylene glycol composition can also be used to increase the circulation half-life of at least one pegylated therapeutic composition as well as restore the pharmacokinetics of the pegylated therapeutic composition in a subject having a high titer of anti-polyethylene glycol antibodies.
FILED Monday, August 27, 2018
APPL NO 16/642722
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1271 (20130101)
A61K 45/06 (20130101)
A61K 47/60 (20170801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813340 Pomper et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland);  Duke University (Durham, North Carolina)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  Duke University (Durham, North Carolina)
INVENTOR(S) Martin G. Pomper (Baltimore, Maryland);  Ronnie C. Mease (Fairfax, Virginia);  Vivek Kumar (Rensselaer, New York);  Sangeeta Ray (Ellicott City, Maryland);  Michael Zalutsky (Chapel Hill, North Carolina);  Ganesan Vaidyanathan (Chapel Hill, North Carolina)
ABSTRACT Small molecule radiohalogenated PSMA inhibitors and metal complexes thereof and their use in radioimaging and radiotherapy for treating PSMA-related diseases, including prostate cancer, are disclosed. The combination of small molecule radiohalogenated PSMA inhibitors with a competitive PSMA ligand for reducing off target accumulation of the radiohalogenated PSMA inhibitor also is disclosed.
FILED Wednesday, February 06, 2019
APPL NO 16/967488
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/0497 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813358 Ramamoorthy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Ayyalusamy Ramamoorthy (Ann Arbor, Michigan);  Thirupathi Ravula (Ann Arbor, Michigan);  Nathaniel Z. Hardin (Ann Arbor, Michigan)
ABSTRACT The disclosure generally relates to lipid nanodiscs, in particular to lipid nanodiscs formed from polymers. A lipid nanodisc according to the disclosure includes a lipid bilayer having a first hydrophilic face and a second hydrophilic face opposing the first hydrophilic face, and a hydrophobic edge between the opposing hydrophilic faces, and a polymer encircling the hydrophobic edge of the lipid bilayer. The polymer includes a first monomeric unit having a pendant hydrophobic group and a second monomeric unit having a backbone hydrophilic group. Methods of making and characterizing the lipid nanodiscs are also disclosed.
FILED Friday, June 05, 2020
APPL NO 16/893772
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1273 (20130101)
A61K 9/1278 (20130101) Original (OR) Class

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/02 (20130101)
C08F 8/32 (20130101)
C08F 220/1804 (20200201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813377 Xie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska)
ASSIGNEE(S) BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska)
INVENTOR(S) Jingwei Xie (Omaha, Nebraska);  Jiang Jiang (Omaha, Nebraska)
ABSTRACT Three dimensional nanofiber structures are provided and methods of production thereof.
FILED Tuesday, May 11, 2021
APPL NO 17/317234
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/70 (20130101)
A61K 9/0092 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101)
A61L 27/38 (20130101)
A61L 27/56 (20130101) Original (OR) Class
A61L 2400/12 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/003 (20130101)
D01D 10/00 (20130101)

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2331/041 (20130101)
D10B 2401/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813390 Epshteyn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Nuwellis, Inc. (Eden Prairie, Minnesota)
ASSIGNEE(S) NUWELLIS, INC. (Eden Prairie, Minnesota)
INVENTOR(S) Vitaliy Gennad'yevich Epshteyn (Maple Grove, Minnesota);  Steven Daniel Sandoval (Eden Prairie, Minnesota);  Kalley Francis Berg (Lino Lakes, Minnesota);  Franz Willems Ulrich (Minneapolis, Minnesota)
ABSTRACT An extracorporeal blood filtering machine can include a blood circuit, an effluent circuit, and a source fluid circuit and can be controlled by a controller. The extracorporeal blood filtering machine can also include access ports for connecting the source fluid circuit to the blood circuit, as well as blood sensors to detect possible issues with the extracorporeal blood filtering machine. The extracorporeal blood filtering machine can include density sensors and flow sensors that enable it to be more accurate and to operate while being transported. The extracorporeal blood filtering machine can further include a user interface and can display fluid inflow/outflow information. A medical fluid container can automatically empty after being filled. An apparatus for supporting a medical fluid container can include a hanger and an attachment member with the apparatus able to adjust to ensure the medical fluid container remains properly oriented directly under a medical fluid container scale.
FILED Monday, February 20, 2023
APPL NO 18/171637
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/14 (20130101)
A61M 1/341 (20140204) Original (OR) Class
A61M 1/342 (20130101)
A61M 1/1601 (20140204)
A61M 1/1643 (20140204)
A61M 1/1694 (20130101)
A61M 1/3403 (20140204)
A61M 1/3627 (20130101)
A61M 1/3644 (20140204)
A61M 2202/0042 (20130101)
A61M 2205/50 (20130101)
A61M 2205/82 (20130101)
A61M 2205/502 (20130101)
A61M 2205/505 (20130101)
A61M 2205/3331 (20130101)
A61M 2205/3379 (20130101)
A61M 2205/3393 (20130101)
A61M 2205/8206 (20130101)
A61M 2205/8262 (20130101)
A61M 2230/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813406 Dicarlo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) James Dicarlo (Cambridge, Massachusetts);  Pouya Bashivan (Cambridge, Massachusetts);  Kohitij Kar (Arlington, Massachusetts)
ABSTRACT Techniques for non-invasively controlling targeted neural activity of a subject are provided herein. The techniques include applying a stimulus input to the subject, the stimulus input being formed by a deep artificial neural network (ANN) model and being configured to elicit targeted neural activity within a brain of the subject. The stimulus input may be a pattern of luminous power generated by the deep ANN model and applied to retinae of the subject. The stimulus input may be generated by the deep ANN model based on a mapping of the subject's neural responses to neurons of the deep ANN model.
FILED Thursday, April 30, 2020
APPL NO 16/863781
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/24 (20210101)
A61B 5/378 (20210101)
A61B 5/7264 (20130101)
A61B 2562/028 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 21/00 (20130101) Original (OR) Class
A61M 2021/005 (20130101)
A61M 2230/10 (20130101)
A61M 2250/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813446 Hubscher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
NIH Office of the Director (NIHOD)
APPLICANT(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
ASSIGNEE(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
INVENTOR(S) Charles S. Hubscher (Louisville, Kentucky);  Susan J. Harkema (Louisville, Kentucky);  April N. Herrity (Peewee Valley, Kentucky);  Yangsheng Chen (Louisville, Kentucky);  Claudia Angeli (Louisville, Kentucky)
ABSTRACT The present invention relates to methods for improvement in lower urinary tract function in an individual with neurogenic urological dysfunction through epidural stimulation of the spinal cord. In certain embodiments, the methods comprise applying a pattern of epidural electrical stimulation to the spinal cord of an individual with impaired lower urinary tract under stimulation parameters sufficient to improve the storage of fluid in the bladder, sensations of fullness and/or emptying, detrusor over-activity, high detrusor pressure, voiding the bladder, transitioning from a storage state to a voiding state, and decreasing detrusor-external urethral sphincter dyssynergia. In certain embodiments, additional patterns of epidural electrical stimulation may be applied simultaneously, such as to maintain a normotensive cardiovascular state of the individual.
FILED Saturday, April 04, 2020
APPL NO 16/840353
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0551 (20130101)
A61N 1/36007 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813482 Krishnaswamy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Venkataramanan Krishnaswamy (Lebanon, New Hampshire);  Brian W. Pogue (Hanover, New Hampshire)
ASSIGNEE(S) DoseOptics LLC (Lebanon, New Hampshire)
INVENTOR(S) Venkataramanan Krishnaswamy (Lebanon, New Hampshire);  Brian W. Pogue (Hanover, New Hampshire)
ABSTRACT The present invention relates to advanced Cherenkov-based imaging systems, tools, and methods of feedback control, temporal control sequence image capture, and quantification in high resolution dose images. In particular, the present invention provides a system and method for simple, accurate, quick, robust, real-time, water-equivalent characterization of beams from LINACs and other systems producing external-therapy radiation for purposes including optimization, commissioning, routine quality auditing, R&D, and manufacture. The present invention also provides a system and method for rapid and economic characterization of complex radiation treatment plans prior to patient exposure. Further, the present invention also provides a system and method of economically detecting Cherenkov radiation emitted by tissue and other media in real-world clinical settings (e.g., settings illuminated by visible light).
FILED Monday, January 24, 2022
APPL NO 17/583167
ART UNIT 2881 — Optics
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1067 (20130101)
A61N 5/1071 (20130101)
A61N 5/1075 (20130101) Original (OR) Class

Measurement of Nuclear or X-radiation
G01T 1/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813485 Xu et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Zhen Xu (Ann Arbor, Michigan);  Clifford Suhyun Cho (Ann Arbor, Michigan)
ABSTRACT Systems and methods for histotripsy and immunotherapy are provided. In some embodiments, histotripsy can be applied to a target tissue volume to lyse and solubilize the target tissue volume to release tumor antigens. In some embodiments, an immune response of the treatment can be evaluated. In other embodiments, an immune therapy can be applied after applying the histotripsy. In one embodiment, the lysed and solubilized cells can be extracted from the tissue. The extracted cells can be used to create immune therapies, including vaccines.
FILED Thursday, January 28, 2021
APPL NO 17/161498
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/0045 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813572 Montgomery et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S) Cellphire, Inc. (Rockville, Maryland)
ASSIGNEE(S) Cellphire, Inc. (Rockville, Maryland)
INVENTOR(S) Joshua Donald Montgomery (Silver Spring, Maryland);  Braden Carl Ishler (Montgomery Village, Maryland);  Stephen Edward Amos (Buckeystown, Maryland);  Keith Andrew Moskowitz (Westfield, Indiana);  Amber Nicole Lee (Montgomery Village, Maryland);  Rafael Jorda (Merignac, France);  Glen Michael Fitzpatrick (North Potomac, Maryland);  Michael Alexander Mathews (Arlington, Virginia)
ABSTRACT Provided herein are materials and methods for the preparation of blood products. In one aspect, provided herein is a composition including platelets or platelet derivatives and an aqueous medium, wherein the aqueous medium has a protein concentration less than 50% of the protein concentration of donor apheresis plasma.
FILED Friday, January 20, 2023
APPL NO 18/099796
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 61/14 (20130101) Original (OR) Class
B01D 2311/12 (20130101)
B01D 2315/10 (20130101)
B01D 2315/16 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0644 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813605 Theberge et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Ashleigh Brooks Theberge (Seattle, Washington);  Erwin Stefan Peter Berthier (Seattle, Washington);  Amanda Haack (Seattle, Washington);  Dakota Kennedy (Seattle, Washington);  Fang Yun Lim (Seattle, Washington)
ABSTRACT A sample vessel includes a biological sample container and a sample stabilizer container. The biological sample container is configured to receive a biological sample and to store the biological sample. The sample stabilizer container is configured to contain a stabilizer associated with the biological sample. The sample stabilizer container is assembled from a stabilizer vial, an adaptor, and a fluid channel. The stabilizer vial is configured to store an amount of the stabilizer. The adaptor is configured to secure the biological sample container and the stabilizer vial such that the biological sample container and the stabilizer vial form the sample vessel. The fluid channel extends through the adaptor from the stabilizer vial to the biological sample container, the biological sample moving from the biological sample container into the stabilizer vial through the fluid channel.
FILED Tuesday, June 29, 2021
APPL NO 17/361322
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/021 (20130101)
B01L 3/523 (20130101)
B01L 3/527 (20130101)
B01L 3/567 (20130101) Original (OR) Class
B01L 3/50273 (20130101)
B01L 3/502738 (20130101)
B01L 2200/16 (20130101)
B01L 2200/141 (20130101)
B01L 2300/042 (20130101)
B01L 2300/049 (20130101)
B01L 2400/0415 (20130101)
B01L 2400/0622 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 35/1002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814009 Shin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  THE UNIVERSITY OF COLORADO (Denver, Colorado)
INVENTOR(S) Kang G. Shin (Ann Arbor, Michigan);  Liang He (Denver, Colorado)
ABSTRACT A driving authentication system is presented for a vehicle. The system includes: a dongle interfaced with a battery of the vehicle and an authenticator configured to receive a discharge current from the battery. The dongle operates to modulate discharge current from the battery with an input code; and the authenticator demodulate the input code from the discharge current, compares the input code to the one or more known authentication codes and, in response to the input code matching one of the one or more known authentication codes, controls power capacity of the battery.
FILED Thursday, March 24, 2022
APPL NO 17/703346
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for
B60R 25/04 (20130101)
B60R 25/23 (20130101) Original (OR) Class
B60R 25/1001 (20130101)

Starting of Combustion Engines; Starting Aids for Such Engines, Not Otherwise Provided for
F02N 11/087 (20130101)
F02N 11/0862 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814341 Pei et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio)
INVENTOR(S) Dehua Pei (Columbus, Ohio);  George Appiah Kubi (Columbus, Ohio);  Ziqing Qian (Wellesley, Massachusetts)
ABSTRACT Disclosed are compounds that can penetrate the mitochondrial membrane and that are able to deliver cargo (e.g., therapeutic agents) specifically to the mitochondria.
FILED Monday, May 06, 2019
APPL NO 17/052935
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/64 (20170801)
A61K 47/542 (20170801)

Acyclic or Carbocyclic Compounds
C07C 279/12 (20130101) Original (OR) Class

Peptides
C07K 5/06086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814365 Pomper et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Martin G. Pomper (Baltimore, Maryland);  Ronnie C. Mease (Fairfax, Virginia);  Ying Chen (Timonium, Maryland);  Sangeeta Ray (Ellicott City, Maryland)
ABSTRACT Compositions and methods for visualizing tissue under illumination with near-infrared radiation, including compounds comprising near-infrared, closed chain, sulfo-cyanine dyes and prostate specific membrane antigen ligands are disclosed.
FILED Friday, June 15, 2018
APPL NO 16/623208
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/19 (20130101)
A61K 9/0053 (20130101)
A61K 49/0032 (20130101)
A61K 49/0052 (20130101)

Heterocyclic Compounds
C07D 403/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814385 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Yu Chen (Tampa, Florida);  Michael Sacco (Tampa, Florida);  James Leahy (Tampa, Florida);  Elena Bray (Tampa, Florida);  Xingmin Sun (Tampa, Florida);  Xiujun Zhang (Tampa, Florida)
ABSTRACT Disclosed herein are compounds that can prevent and treat C. difficile by inhibiting sporulation. Also disclosed herein are compositions and formulations comprising the compound disclosed herein. Methods of preventing and treating C. difficile comprising administering the compounds described herein are also disclosed.
FILED Monday, June 27, 2022
APPL NO 17/850650
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 471/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814396 Dai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana);  University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana);  University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Mingji Dai (Alpharetta, Georgia);  Dexter Cameron Davis (Watertown, Massachusetts);  Alexander Adibekian (Palm City, Florida);  Dominic Gregor Hoch (Jupiter, Florida);  Zhong-Yin Zhang (West Lafayette, Indiana)
ABSTRACT The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.
FILED Monday, May 03, 2021
APPL NO 17/246775
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 493/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814440 Maris et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania);  THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF THE HEALTH AND HUMAN SERVICES (Rockville, Maryland)
ASSIGNEE(S) The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania);  The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) John M. Maris (Philadelphia, Pennsylvania);  Kristopher R. Bosse (Philadelphia, Pennsylvania);  Dimiter Dimitrov (Frederick, Maryland);  Zhongyu Zhu (Frederick, Maryland);  Dontcho V. Jelev (Rockville, Maryland)
ABSTRACT The present disclosure is directed to antibodies binding to Glypican 2 and methods of using such antibodies to treat cancers that express or overexpress the Glypican 2 antigen.
FILED Tuesday, November 08, 2016
APPL NO 15/773256
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 47/6889 (20170801)
A61K 47/6929 (20170801)
A61K 2039/572 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/7051 (20130101)
C07K 16/18 (20130101)
C07K 16/30 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814464 Saltzman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) W. Mark Saltzman (New Haven, Connecticut);  Yuhang Jiang (New Haven, Connecticut)
ABSTRACT Poly(amine-co-ester) polymers, methods of forming active agent-load polyplexes and particles therefrom, and methods of using them for delivery of nucleic acid agents with optimal uptake have been developed. Examples demonstrate critical molecular weights in combination with exposed carboxylic and/or hydroxyl groups, and methods of making. Typically, the compositions are less toxic, more efficient at drug delivery, or a combination thereof compared to a control other transfection reagents. In some embodiments, the compositions are suitable for in vivo delivery, and can be administered systemically to a subject to treat a disease or condition.
FILED Wednesday, April 29, 2020
APPL NO 16/862491
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/595 (20170801)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/685 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814526 Cheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa)
INVENTOR(S) Elise Lin Cheng (Iowa City, Iowa);  C. Allan Guymon (Iowa City, Iowa);  Marian R. Hansen (Solon, Iowa);  Braden Leigh (Iowa City, Iowa)
ABSTRACT Durable, anti-fouling, crosslinked zwitterionic coatings that are grafted to the surface of a substrate through covalent bonding are disclosed. When exposed to a light source, zwitterionic monomers react with a crosslinker and with activated radicals at the surface of the substrate, simultaneously forming the crosslinked zwitterionic coating and anchoring it to the surface of the substrate. Photomasking techniques can be used to micropattern the zwitterionic coatings. The zwitterionic coatings can be applied to a variety of substrates, including medical devices and systems.
FILED Monday, December 12, 2022
APPL NO 18/079085
ART UNIT 1759 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/16 (20130101)
A61L 27/34 (20130101)
A61L 29/041 (20130101)
A61L 29/085 (20130101)
A61L 31/10 (20130101)
A61L 31/048 (20130101)
A61L 2300/404 (20130101)
A61L 2420/08 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/11 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/1675 (20130101)
C09D 133/10 (20130101) Original (OR) Class
C09D 133/26 (20130101)
C09D 151/085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814624 Roth et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Theodore Lee Roth (San Francisco, California);  Alexander Marson (San Francisco, California)
ABSTRACT Provided herein are methods and compositions for editing the genome of a cell. In some embodiments, a nucleotide sequence of at least 200 nucleotides in length is inserted into a target region in the genome of a cell.
FILED Monday, October 11, 2021
APPL NO 17/498531
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/90 (20130101)
C12N 15/102 (20130101)
C12N 15/1138 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2320/53 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814626 Nguyen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Research Foundation for The State University of New York (Buffalo, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Amherst, New York)
INVENTOR(S) Juliane Nguyen (Buffalo, New York);  Scott Ferguson (North Tonawanda, New York)
ABSTRACT Presented are RNA nucleotide sequences referred to as EXO-Codes, and longer RNA polynucleotides that contain the EXO-Codes. EXO-Codes provide RNA with the ability to a) be selectively sorted to extracellular vesicles such as exosomes, and b) deliver a variety of cargo types to program or reprogram the extracellular vesicles, and cells that receive the exosomes. Also presented are methods of making the EXO-Codes, modifying cells using the EXO-Codes, expression vectors encoding the EXO-Codes, and exosomes and other secreted vesicles that include RNA polynucleotides that contain the EXO-Codes.
FILED Friday, May 11, 2018
APPL NO 16/612734
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5068 (20130101)
A61K 31/713 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101) Original (OR) Class
C12N 15/111 (20130101)
C12N 2310/20 (20170501)
C12N 2310/141 (20130101)
C12N 2310/3519 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814627 Chang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California);  EMORY UNIVERSITY (Atlanta, Georgia)
ASSIGNEE(S) THE BOARD OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California);  EMORY UNIVERSITY (Atlanta, Georgia)
INVENTOR(S) Howard Y. Chang (Stanford, California);  Ye Grace Chen (Stanford, California);  Bali Pulendran (Stanford, California);  Sudhir Kasturi (Atlanta, Georgia)
ABSTRACT Compositions and methods of modulating an innate immune response with circular RNAs are disclosed. In particular, the disclosure relates to methods for modifying an RNA by circularization and the use of circular RNAs generated with exogenous introns to stimulate an innate immune response or circular RNAs generated with endogenous introns to prevent immune recognition of foreign RNA.
FILED Thursday, June 15, 2017
APPL NO 16/311770
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39 (20130101)
A61K 2039/55555 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/67 (20130101) Original (OR) Class
C12N 15/117 (20130101)
C12N 2310/17 (20130101)
C12N 2310/532 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814655 Barnes et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) DNA POLYMERASE TECHNOLOGY, INC. (St. Louis, Missouri)
ASSIGNEE(S) DNA POLYMERASE TECHNOLOGY, INC. (St. Louis, Missouri)
INVENTOR(S) Wayne M. Barnes (University City, Missouri);  Milko B. Kermekchiev (St. Louis, Missouri);  Zhian Zhang (Ballwin, Missouri)
ABSTRACT Provided are mutant polymerases having DNA polymerase activity and reverse transcriptase activity or strand displacement activity, along with target nucleic acid amplification methods employing such mutant polymerases.
FILED Friday, May 28, 2021
APPL NO 17/303445
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1252 (20130101) Original (OR) Class
C12N 9/1276 (20130101)
C12N 15/1096 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6846 (20130101)
C12Q 1/6846 (20130101)
C12Q 2521/101 (20130101)
C12Q 2521/101 (20130101)
C12Q 2521/107 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/119 (20130101)
C12Q 2531/119 (20130101)

Enzymes
C12Y 207/07007 (20130101)
C12Y 207/07049 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814674 Ng
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Fei Fan Ng (Decatur, Georgia)
ABSTRACT Methods for the rapid amplification of extremely low quantity nucleic acids in a sample are provided. The disclosed methods are capable of amplifying less than 1 pg of DNA and/or RNA from a biological sample using a single tube and one-step or two-step preparation.
FILED Friday, February 01, 2019
APPL NO 16/965856
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101) Original (OR) Class
C12Q 1/6806 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814677 Guo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Jia Guo (Tempe, Arizona);  Joshua LaBaer (Chandler, Arizona)
ABSTRACT Provided herein are methods and systems for sensitive and multiplexed in situ analysis of samples such as biological samples using cleavable hapten linked targeting agents and cleavable detectably-labeled hapten-binding agents. In particular, provided herein are methods for multiplexed single-cell in situ biomolecule profiling in samples, including fixed or fresh tissues, and also allows the investigation of the different cell compositions and their spatial organizations in intact tissues through consecutive cycles of probe hybridization, fluorescence imaging, and signal removal.
FILED Wednesday, December 30, 2020
APPL NO 17/138287
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 1/6876 (20130101)
C12Q 2563/131 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814680 Grillari et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Universität für Bodenkultur Wien (Vienna, Austria);  Buck Institute for Research on Aging (Novato, California)
ASSIGNEE(S) BUCK INSTITUTE FOR RESEARCH ON AGING (Novato, California);  UNIVERSITÄT FÜR BODENKULTUR WIEN (Vienna, Austria)
INVENTOR(S) Johannes Grillari (Bisamberg, Austria);  Matthias Hackl (Bisamberg, Austria);  Judith Campisi (Berkeley, California);  Abhijit Kale (Novato, California)
ABSTRACT The present invention provides a method of detecting senescent cells or diagnosing cellular senescence in a subject wherein the level of one or more selected miRNAs is quantified in a sample from said subject.
FILED Tuesday, June 26, 2018
APPL NO 16/625632
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6851 (20130101)
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814687 Kim et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts);  Baylor College of Medicine (Houston, Texas);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Northwestern University (Evanston, Illinois);  The Johns Hopkins University (Baltimore, Maryland);  United States Government as represented by the U.S. Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts);  Baylor College of Medicine (Houston, Texas);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Northwestern University (Evanston, Illinois);  The Johns Hopkins University (Baltimore, Maryland);  United States Government as represented by the U.S. Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Jaegil Kim (Cambridge, Massachusetts);  Gad Getz (Boston, Massachusetts);  Seth Paul Lerner (Houston, Texas);  David Kwiatkowski (Boston, Massachusetts);  Joshua Meeks (Evanston, Illinois);  Joaquim Bellmunt (Cambridge, Massachusetts);  David McConkey (Baltimore, Maryland)
ABSTRACT The present invention features methods for characterizing mutational profiles in patients with bladder cancer.
FILED Friday, August 07, 2020
APPL NO 16/988317
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815142 Wellborn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Science Foundation (NSF)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) Patrick Wellborn (Nashville, Tennessee);  Jason Mitchell (Nashville, Tennessee);  Robert Webster, III (Nashville, Tennessee)
ABSTRACT This disclosure relates to a magnetorheological (MR) brake. The MR brake includes a rotor constructed at least partially of a ferromagnetic material, and a housing that supports the rotor such that the rotor and the housing are rotatable relative to each other about an axis, wherein the housing and rotor are configured such that a fluid gap is defined between the housing and the rotor, and wherein portions of the housing adjacent the rotor are constructed at least partially of a ferromagnetic material. An MR fluid is disposed in the fluid gap. A current-carrying coil is excitable to generate a magnetic field within ferromagnetic portions of the rotor and the housing and acts on the MR fluid. At least one element constructed of a material having low magnetic permeability is configured route the lines of magnetic flux through surrounding higher permeability material on opposite sides of the fluid gap.
FILED Monday, February 03, 2020
APPL NO 17/428052
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Couplings for Transmitting Rotation; Clutches; Brakes
F16D 57/002 (20130101) Original (OR) Class
F16D 2121/20 (20130101)
F16D 2131/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815456 Cui
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S) Meng Cui (West Lafayette, Indiana)
ABSTRACT Systems and methods for analyzing samples, such as tissue samples, and measuring the emissions when these samples are exposed to light are disclosed. Embodiments include illuminating multiple target locations on a sample with laser light, which may first be manipulated by a scanner, and receiving decaying emissions from the target location. At least some embodiments include the emissions traveling backwards along a substantial portion of the laser light pathway and being received by a detector. Additional embodiments include converting the received emissions into streak lines of position versus time, converting the streak lines to plots of signal strength versus time, and curve fitting the plots to determine representative decay times. In some embodiments, the decay times are presented as plots of position on the surface of the sample versus emission strength, which may be color coded. Some embodiment dwell on each target location for multiple scans of the laser.
FILED Wednesday, August 25, 2021
APPL NO 17/445945
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6408 (20130101) Original (OR) Class
G01N 2201/1053 (20130101)
G01N 2201/06113 (20130101)

Image Data Processing or Generation, in General
G06T 11/001 (20130101)
G06T 11/206 (20130101)

Pictorial Communication, e.g Television
H04N 23/56 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815514 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Juno Therapeutics, Inc. (Seattle, Washington);  Fred Hutchinson Cancer Center (Seattle, Washington)
ASSIGNEE(S) Juno Therapeutics, Inc. (Seattle, Washington);  Fred Hutchinson Cancer Research Center (Seattle, Washington)
INVENTOR(S) He Li (Seattle, Washington);  Mark J. Gilbert (Seattle, Washington);  David Maloney (Seattle, Washington);  Stanley R. Riddell (Seattle, Washington);  Cameron J. Turtle (Seattle, Washington)
ABSTRACT Provided are methods, kits and compositions related to toxicity associated with administration of cell therapy for the treatment of diseases or conditions, e.g., cancer, including methods for use in predicting and treating a toxicity. In some embodiments, the toxicity is a neurotoxicity or cytokine release syndrome (CRS), such as a severe neurotoxicity or a severe CRS. The methods generally involve detecting a parameter of a biomarker or individually a parameter of each biomarker in a panel of biomarkers, such as a concentration, amount or activity, and comparing the detected parameter to a reference value for the parameter to determine if the subject is at risk for developing the toxicity, such as neurotoxicity or CRS or severe neurotoxicity or severe CRS. In some embodiments, the methods further involve administering an agent or therapy for treating, ameliorating, preventing, delaying and/or attenuating the development of the toxicity, such as neurotoxicity or CRS, such as severe neurotoxicity or severe CRS.
FILED Friday, December 02, 2016
APPL NO 15/781089
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101)
A61K 2039/5156 (20130101)
A61K 2039/5158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6863 (20130101) Original (OR) Class
G01N 33/6866 (20130101)
G01N 33/6869 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817204 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio);  The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Nathaniel Braman (Bethel Park, Pennsylvania);  Tristan Maidment (Cleveland, Ohio);  Yijiang Chen (Cleveland, Ohio)
ABSTRACT Embodiments discussed herein facilitate determination of whether lesions are benign or malignant. One example embodiment is a method, comprising: accessing medical imaging scan(s) that are each associated with distinct angle(s) and each comprise a segmented region of interest (ROI) of that medical imaging scan comprising a lesion associated with a first region and a second region; providing the first region(s) of the medical imaging scan(s) to trained first deep learning (DL) model(s) of an ensemble and the second region(s) of the medical imaging scan(s) to trained second DL model(s) of the ensemble; and receiving, from the ensemble of DL models, an indication of whether the lesion is a benign architectural distortion (AD) or a malignant AD.
FILED Wednesday, December 09, 2020
APPL NO 17/116366
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/025 (20130101)
A61B 6/469 (20130101)
A61B 6/502 (20130101)
A61B 6/5217 (20130101)

Electric Digital Data Processing
G06F 18/214 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101)
G06T 2207/10112 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30068 (20130101)
G06T 2207/30096 (20130101)

Image or Video Recognition or Understanding
G06V 10/25 (20220101)
G06V 10/82 (20220101)
G06V 10/764 (20220101)
G06V 2201/03 (20220101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101) Original (OR) Class
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11813051 Harshman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Sean W. Harshman (Fairborn, Ohio);  Brian A. Geier (Fairborn, Ohio);  Claude C. Gigsby (Beavercreek, Ohio);  Jeffrey B. Phillips (Centerville, Ohio);  Darrin K. Ott (Waynesville, Ohio)
ABSTRACT A method of detecting hypoxia. Detecting hypoxia includes detecting, in exhaled breath, at least one indicator for hypoxia. The at least one indicator is selected from the group consisting of pentanal, 2-pentanone, 2-hexanone, 2-heptanone, 2-cyclopenten-1-one, and 4-butyrolactone.
FILED Thursday, June 17, 2021
APPL NO 17/350654
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/087 (20130101)
A61B 5/0833 (20130101) Original (OR) Class
A61B 5/0836 (20130101)
A61B 2010/0087 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 16/10 (20130101)
A61M 16/024 (20170801)
A61M 2016/0036 (20130101)
A61M 2202/0007 (20130101)
A61M 2202/0208 (20130101)
A61M 2202/0208 (20130101)
A61M 2205/50 (20130101)
A61M 2205/3303 (20130101)
A61M 2230/432 (20130101)
A61M 2230/435 (20130101)

Devices, Apparatus or Methods for Life-saving
A62B 7/14 (20130101)
A62B 9/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813054 Dawson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Geospatial Intelligence Agency (NGA)
National Science Foundation (NSF)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Geraldine Dawson (Durham, North Carolina);  Guillermo Sapiro (Durham, North Carolina);  Jordan Hashemi (Durham, North Carolina)
ABSTRACT The subject matter described herein includes methods, systems, and computer readable media for conducting an automatic assessment of postural control of a subject. According to one aspect, a method occurs at a computing platform including a processor and memory. The method includes displaying a stimulus to which a subject responds, capturing facial image data of the subject, analyzing the facial image data to determine a frequency of head displacement information associated with the subject, using the head displacement information to derive postural control assessment data, and determining that the postural control assessment data is indicative of a neurodevelopmental or neuropsychiatric disorder associated with the subject.
FILED Friday, November 08, 2019
APPL NO 16/678828
ART UNIT 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1116 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 3/012 (20130101)
G06F 3/017 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/70 (20170101)
G06T 2207/30201 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813100 Tichauer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) The Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Kenneth M. Tichauer (Chicago, Illinois);  Scott C. Davis (Woodville, New Hampshire);  Brian William Pogue (Hanover, New Hampshire)
ABSTRACT An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images.
FILED Monday, January 09, 2017
APPL NO 15/402077
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 6/032 (20130101)
A61B 6/037 (20130101)
A61B 6/481 (20130101) Original (OR) Class
A61B 6/4417 (20130101)
A61B 6/5235 (20130101)
A61B 6/5247 (20130101)

Image Data Processing or Generation, in General
G06T 5/50 (20130101)
G06T 2207/10081 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/10104 (20130101)
G06T 2207/10108 (20130101)
G06T 2207/20224 (20130101)
G06T 2207/30024 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813124 Reichenbach et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Mark Reichenbach (Lincoln, Nebraska);  Shane Farritor (Lincoln, Nebraska)
ABSTRACT Disclosed herein are gross positioning systems for use with robotic surgical devices to provide gross positioning of the robotic surgical devices. The gross positioning systems have a base, a first arm link operably coupled to the base, a second arm link operably coupled to the first arm link, a third arm link operably coupled to the second arm link, and a slidable coupling component slidably coupled to the third arm link.
FILED Monday, June 13, 2022
APPL NO 17/838883
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/00149 (20130101)
A61B 17/0206 (20130101)
A61B 34/30 (20160201)
A61B 34/73 (20160201)
A61B 90/50 (20160201) Original (OR) Class
A61B 2017/00477 (20130101)
A61B 2034/302 (20160201)
A61B 2218/002 (20130101)
A61B 2218/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813284 Doxey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Novan, Inc. (Durham, North Carolina)
ASSIGNEE(S) Novan, Inc. (Durham, North Carolina)
INVENTOR(S) Ryan Doxey (Raleigh, North Carolina);  Jian Bao (Cary, North Carolina)
ABSTRACT The present invention generally relates to topical compositions and methods of using the same. A preferred topical pharmaceutical composition comprises a nitric oxide-releasing active pharmaceutical ingredient in admixture with a hydrophilic composition and a hydrophobic composition wherein the nitric oxide-releasing active pharmaceutical ingredient comprises a nitric oxide-releasing compound having a diazeniumdiolate functional group.
FILED Friday, August 08, 2014
APPL NO 14/910207
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 8/25 (20130101)
A61K 8/042 (20130101)
A61K 8/345 (20130101)
A61K 8/898 (20130101)
A61K 9/06 (20130101)
A61K 9/10 (20130101)
A61K 9/0014 (20130101)
A61K 9/107 (20130101)
A61K 33/00 (20130101) Original (OR) Class
A61K 47/02 (20130101)
A61K 47/10 (20130101)
A61K 47/12 (20130101)
A61K 47/14 (20130101)
A61K 47/32 (20130101)
A61K 47/38 (20130101)
A61K 47/44 (20130101)
A61K 47/52 (20170801)
A61K 47/59 (20170801)
A61K 2800/22 (20130101)

Specific Use of Cosmetics or Similar Toilet Preparations
A61Q 17/005 (20130101)
A61Q 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813338 Delikatny et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
INVENTOR(S) Edward J. Delikatny (Havertown, Pennsylvania);  Anatoliy V. Popov (Philadelphia, Pennsylvania);  Sean P. Arlauckas (Philadelphia, Pennsylvania)
ABSTRACT The invention relates to compositions and methods for diagnosing as well as treating cancer diseases associated with choline kinase (ChoK). Specifically, the invention relates to a composition comprising an intrinsically fluorescent choline kinase (ChoK) inhibitor or a ChoK inhibitor operably linked to a fluorescent dye. The composition is capable of diagnosing and/or treating cancer diseases associated with ChoK.
FILED Wednesday, March 12, 2014
APPL NO 14/774524
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/404 (20130101)
A61K 31/444 (20130101)
A61K 31/5377 (20130101)
A61K 47/55 (20170801)
A61K 49/0032 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813406 Dicarlo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) James Dicarlo (Cambridge, Massachusetts);  Pouya Bashivan (Cambridge, Massachusetts);  Kohitij Kar (Arlington, Massachusetts)
ABSTRACT Techniques for non-invasively controlling targeted neural activity of a subject are provided herein. The techniques include applying a stimulus input to the subject, the stimulus input being formed by a deep artificial neural network (ANN) model and being configured to elicit targeted neural activity within a brain of the subject. The stimulus input may be a pattern of luminous power generated by the deep ANN model and applied to retinae of the subject. The stimulus input may be generated by the deep ANN model based on a mapping of the subject's neural responses to neurons of the deep ANN model.
FILED Thursday, April 30, 2020
APPL NO 16/863781
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/24 (20210101)
A61B 5/378 (20210101)
A61B 5/7264 (20130101)
A61B 2562/028 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 21/00 (20130101) Original (OR) Class
A61M 2021/005 (20130101)
A61M 2230/10 (20130101)
A61M 2250/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813642 Semperlotti et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Fabio Semperlotti (West Lafayette, Indiana);  Ting-Wei Liu (West Lafayette, Indiana)
ABSTRACT A system includes a first structure, wherein the first structure lacks space inversion symmetry, and wherein the first structure includes a first elastic lattice. The system further includes a second structure, wherein the second structure lacks space inversion symmetry, and wherein the second structure includes a second elastic lattice. Additionally, the system includes the first structure coupled to the second structure such that the first structure and the second structure have a mirror symmetry to each other.
FILED Thursday, July 26, 2018
APPL NO 16/046982
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/18 (20130101)
B06B 3/00 (20130101) Original (OR) Class

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/24 (20130101)

Electric Machines Not Otherwise Provided for
H02N 2/186 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813829 Ma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Ruilong Ma (Atlanta, Georgia);  Vladimirv V. Tsukruk (Atlanta, Georgia)
ABSTRACT In a method for making a flexible material, a sheet of graphene oxide-composite paper is subjected to an environment having a relative humidity above a predetermined threshold for a predetermined amount of time. At least one expansion cut is cut in the sheet of graphene oxide-composite paper. A flexible conductive material includes a sheet of graphene oxide-composite paper defining at least one cut passing therethrough and formed it a kirigami structure. A region of the sheet of graphene oxide-composite paper includes reduced graphene oxide.
FILED Wednesday, July 10, 2019
APPL NO 16/507479
ART UNIT 1783 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 29/02 (20130101)
B32B 29/06 (20130101) Original (OR) Class
B32B 2264/102 (20130101)
B32B 2457/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Electric Machines Not Otherwise Provided for
H02N 1/04 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/30 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814323 Apostolov
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Zlatomir D. Apostolov (Beavercreek, Ohio)
ABSTRACT The present disclosure includes a system and method for monitoring degradation of a high temperature composite component (HTC). The HTC is defined by a volume that includes a matrix material and a fiber formed from at least one of ceramic and carbon material. One or more electrical conductors are disposed within the volume and connected directly or indirectly to a monitoring system.
FILED Tuesday, April 06, 2021
APPL NO 17/223339
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/62231 (20130101)
C04B 35/62272 (20130101) Original (OR) Class
C04B 2111/94 (20130101)
C04B 2235/40 (20130101)
C04B 2235/522 (20130101)
C04B 2235/5248 (20130101)
C04B 2235/5256 (20130101)
C04B 2235/5288 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814326 Cook et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Gary Cook (Beavercreek, Ohio);  Ronald W. Stites (Beavercreek, Ohio)
ABSTRACT A method of forming a doped substrate comprises heating a substrate comprising a layer of a dopant on at least one surface to a predetermined temperature; applying a predetermined degree of isostatic external pressure on the surface of said substrate at said predetermined temperature for a time sufficient to induce thermal migration of the dopant into the substrate to provide a doped substrate; and removing the isostatic pressure and cooling the doped substrate to about room temperature. The substrate is a glass material, a single crystal material, a poly-crystalline material, a ceramic material, or a semiconductor material, and the substrate may be optically transparent. The dopant comprises one or more transition metals, one or more rare earth elements, or a combination of both. The layer of a dopant comprises one or more segregated layers of distinct chemical species. The isostatic pressure and elevated temperature may be applied simultaneously or sequentially.
FILED Monday, April 03, 2017
APPL NO 16/067209
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/547 (20130101)
C04B 41/009 (20130101)
C04B 41/0072 (20130101)
C04B 41/4517 (20130101)
C04B 41/4521 (20130101)
C04B 41/5133 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814440 Maris et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania);  THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF THE HEALTH AND HUMAN SERVICES (Rockville, Maryland)
ASSIGNEE(S) The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania);  The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) John M. Maris (Philadelphia, Pennsylvania);  Kristopher R. Bosse (Philadelphia, Pennsylvania);  Dimiter Dimitrov (Frederick, Maryland);  Zhongyu Zhu (Frederick, Maryland);  Dontcho V. Jelev (Rockville, Maryland)
ABSTRACT The present disclosure is directed to antibodies binding to Glypican 2 and methods of using such antibodies to treat cancers that express or overexpress the Glypican 2 antigen.
FILED Tuesday, November 08, 2016
APPL NO 15/773256
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 47/6889 (20170801)
A61K 47/6929 (20170801)
A61K 2039/572 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/7051 (20130101)
C07K 16/18 (20130101)
C07K 16/30 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814563 Safir et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Zymergen Inc. (Emeryville, California);  Kent State University (Kent, Ohio)
ASSIGNEE(S) Zymergen Inc. (Emeryville, California);  Kent State University (Kent, Ohio)
INVENTOR(S) Adam Safir (Berkeley, California);  Shilpa Naresh Raja (Emeryville, California);  Arjan Zoombelt (Emeryville, California);  Robert J. Twieg (Kent, Ohio);  Pawan Nepal (Kent, Ohio);  Ashani Wedige-Fernando (Kent, Ohio);  Peter Palffy-Muhoray (Kent, Ohio)
ABSTRACT The disclosure discusses chiral dopants for liquid-crystalline materials. Chiral dopants can be bioreachable compounds, i.e. compounds produced from microbes through fermentation. Chiral dopants can also include bioreachable materials that are further modified by chemical synthetic steps. Chiral dopants as discussed herein can include biomolecules such as glycyrrhetinic acid (1), S-naringenin (2), shikimic acid (3), alpha-phellandrene (4), betulin (5), malic acid (6), valencene (7), or nootkatone (8), and any stereoisomers or chemically modified derivatives thereof. The disclosure further shows optical properties of such compounds in a liquid-crystalline material.
FILED Friday, December 06, 2019
APPL NO 17/299777
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 19/588 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814621 Jewett et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Michael Christopher Jewett (Evanston, Illinois);  Joongoo Lee (Evanston, Illinois);  Jeffrey S. Moore (Savoy, Illinois);  Kenneth E. Schwieter (Champaign, Illinois);  Kevin Jerome Schwarz (Champaign, Illinois)
ABSTRACT Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.
FILED Monday, June 03, 2019
APPL NO 15/734182
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/351 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814659 Stephanopoulos et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Nicholas Stephanopoulos (Scottsdale, Arizona);  Yang Xu (Chandler, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Nicholas Stephanopoulos (Scottsdale, Arizona);  Yang Xu (Chandler, Arizona)
ABSTRACT Described herein are polyhedral, three-dimensional tunable nanocages assembled with a multimeric protein covalently linked to a polynucleotide handle and a DNA origami base assembly including sequences complementary to the polynucleotide handles, wherein the polynucleotide handle and the complementary sequences hybridize to for double-stranded DNA helices.
FILED Wednesday, March 11, 2020
APPL NO 16/816029
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 19/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/88 (20130101) Original (OR) Class
C12N 15/11 (20130101)

Enzymes
C12Y 401/02014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815311 Johnson et al.
FUNDED BY
Department of Defense (DOD)
United States Special Operations Command (SOCOM)
APPLICANT(S) Terumo BCT Biotechnologies, LLC (Lakewood, Colorado)
ASSIGNEE(S) Terumo BCT Biotechnologies, LLC (Lakewood, Colorado)
INVENTOR(S) Nathaniel T. Johnson (Highlands Ranch, Colorado);  Rylan A. Summit (Denver, Colorado);  Dennis A. Bridges (Arvada, Colorado);  Dennis J. Hlavinka (Arvada, Colorado);  Kestas P. Parakininkas (Englewood, Colorado);  Kirk L. Weimer (Green Valley, Arizona);  Michael Lawrence Glover (Lakewood, Colorado);  Alexander Du Nguyen (Denver, Colorado);  Margaret V. Kwiat (Evergreen, Colorado)
ABSTRACT Provided is a gas fill fixture for use in lyophilization, a related system and method. The gas fill fixture includes a chassis, fill indicator and a lid, such that the chassis and lid together form a cavity for receiving a flexible lyophilization container. The system includes a lyophilization container, a lyophilizer and a gas fill fixture incorporating a chassis, a fill indicator and a lid. The method includes process steps for using the system to lyophilize a fluid.
FILED Tuesday, September 06, 2022
APPL NO 17/903506
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0252 (20130101)
A01N 1/0263 (20130101)
A01N 1/0284 (20130101)
A01N 1/0289 (20130101)

Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle
A61J 1/10 (20130101)
A61J 1/1468 (20150501)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/0277 (20140204)
A61M 2202/0415 (20130101)
A61M 2205/584 (20130101)
A61M 2205/3389 (20130101)

Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages
B65D 51/241 (20130101)

Drying Solid Materials or Objects by Removing Liquid Therefrom
F26B 5/06 (20130101) Original (OR) Class
F26B 21/14 (20130101)
F26B 25/18 (20130101)
F26B 25/063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815528 Grinolds et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Michael S. Grinolds (Cambridge, Massachusetts);  Sungkun Hong (Cambridge, Massachusetts);  Patrick Maletinsky (Cambridge, Massachusetts);  Amir Yacoby (Cambridge, Massachusetts)
ABSTRACT A sensing probe may be formed of a diamond material comprising one or more spin defects that are configured to emit fluorescent light and are located no more than 50 nm from a sensing surface of the sensing probe. The sensing probe may include an optical outcoupling structure formed by the diamond material and configured to optically guide the fluorescent light toward an output end of the optical outcoupling structure. An optical detector may detect the fluorescent light that is emitted from the spin defects and that exits through the output end of the optical outcoupling structure after being optically guided therethrough. A mounting system may hold the sensing probe and control a distance between the sensing surface of the sensing probe and a surface of a sample while permitting relative motion between the sensing surface and the sample surface.
FILED Friday, February 18, 2022
APPL NO 17/675156
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/645 (20130101)
G01N 24/10 (20130101)
G01N 2201/10 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 30/025 (20130101)
G01Q 60/08 (20130101)
G01Q 60/38 (20130101)
G01Q 60/54 (20130101)
G01Q 70/14 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/022 (20130101)
G01R 33/032 (20130101)
G01R 33/60 (20130101)
G01R 33/323 (20130101)
G01R 33/1284 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815653 Ulmer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Warfare Center (NAWC)
APPLICANT(S) INTELLISENSE SYSTEMS, INC. (Torrance, California)
ASSIGNEE(S) INTELLISENSE SYSTEMS, INC. (Torrance, California)
INVENTOR(S) Christopher Ulmer (San Pedro, California);  David Miller (San Pedro, California);  Anthony Michael (Los Angeles, California);  Thomas Vu (Rancho Palos Verdes, California);  Jeffrey Norell (Los Angeles, California);  David Gustavson (Los Angeles, California);  Gregory Peng (Long Beach, California);  Drew Yenzer (Culver City, California);  Haider Rasool (Redondo Beach, California)
ABSTRACT An assembly and method for using weather sensors with enhanced modular capability is disclosed. The weather sensor assembly generally comprises a cap module, middle module, and a base module, where the cap module, middle module(s) and the base module are stacked adjacently to provide environmental sealing, weather sensing, and electrical connectivity to the weather sensor assembly. One or more ring mechanisms may be included that interlock the cap module, middle module(s), base module to form the weather sensor assembly into an integrated unit. Moreover, the ring mechanisms enable further modules to be added to the weather sensor assembly for additional capabilities. By doing so, each of the modules in the weather sensor assembly may be independent units that can be removed, reordered, swapped, and added for desired sensing modalities and environments.
FILED Friday, January 20, 2023
APPL NO 18/099716
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Meteorology
G01W 1/04 (20130101) Original (OR) Class
G01W 1/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815668 Devlin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Multidisciplinary University Research Initiative (MURI)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts);  THE CHARLES STARK DRAPER LABORATORY, INC. (Cambridge, Massachusetts)
INVENTOR(S) Robert C. Devlin (Cambridge, Massachusetts);  Mohammadreza Khorasaninejad (Cambridge, Massachusetts);  Federico Capasso (Cambridge, Massachusetts);  Hongkun Park (Cambridge, Massachusetts);  Alexander Arthur High (Cambridge, Massachusetts)
ABSTRACT A method of fabricating a visible spectrum optical component includes: providing a substrate; forming a resist layer over a surface of the substrate; patterning the resist layer to form a patterned resist layer defining openings exposing portions of the surface of the substrate; performing deposition to form a dielectric film over the patterned resist layer and over the exposed portions of the surface of the substrate, wherein a top surface of the dielectric film is above a top surface of the patterned resist layer; removing a top portion of the dielectric film to expose the top surface of the patterned resist layer and top surfaces of dielectric units within the openings of the patterned resist layer; and removing the patterned resist layer to retain the dielectric units over the substrate.
FILED Wednesday, May 25, 2022
APPL NO 17/824823
ART UNIT 2872 — Optics
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/042 (20130101)
C23C 16/56 (20130101)
C23C 16/45525 (20130101)
C23C 16/45555 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 1/02 (20130101)
G02B 1/005 (20130101)
G02B 13/14 (20130101) Original (OR) Class

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0005 (20130101)
G03F 7/40 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815671 Valentine et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Jason G. Valentine (Nashville, Tennessee);  You Zhou (Nashville, Tennessee);  Hanyu Zheng (Nashville, Tennessee)
ABSTRACT A 2D spatial differentiator operates in transmission and comprises a Si nanorod photonic crystal that can transform an image, Ein, into its second-order derivative, Eout α ∇2 Ein, allowing for direct discrimination of the edges in the image. The use of a 2D photonic crystal allows for differentiation and edge detection in all directions with a numerical aperture (NA) up to 0.315 and an experimental resolution smaller than 4 μm. The nanophotonic differentiator is able to be directly integrated into an optical microscope and onto a camera sensor, demonstrating the ease with which it can be vertically integrated into existing imaging systems. Furthermore, integration with a metalens is demonstrated for realizing a compact and monolithic image-processing system. In all cases, the use of the nanophotonic differentiator allows for a significant reduction in size compared to traditional systems, opening new doors for optical analog image processing in applications involving computer vision.
FILED Friday, September 04, 2020
APPL NO 17/012189
ART UNIT 2871 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 1/005 (20130101)
G02B 3/0056 (20130101)
G02B 21/12 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 23/54 (20230101)
H04N 23/56 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815984 Toupal et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Tina C. Toupal (Portland, Oregon);  Shamsul Abedin (Portland, Oregon)
ABSTRACT A system level error detection and handling of the network IO in a multi-chip-package (MCP) die is provided. The error detection and handling mechanism conceived may be used between a system-on-chip (SoC) die and a different type of die, such as a die manufactured by a third-party (e.g., a high-bandwidth network IO die). To provide a timely indication in case of any part of the network is at fault, a control unit on the SoC die handles error detection on the network IO links using various indicators. After errors are detected, the control unit groups the errors into two categories: a link failure and a virtual channel failure. Such an error handling mechanism may consolidate the actions and provide consistency in hardware behavior.
FILED Friday, February 07, 2020
APPL NO 16/784768
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 9/4812 (20130101)
G06F 11/0757 (20130101) Original (OR) Class
G06F 13/4068 (20130101)
G06F 15/7807 (20130101)

Transmission
H04B 10/801 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 12/5601 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11816018 Shao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Zhong Shao (Branford, Connecticut);  Ronghui Gu (New Haven, Connecticut);  Vilhelm Sjoberg (New Haven, Connecticut);  Jieung Kim (New Haven, Connecticut);  Jeremie Koenig (New Haven, Connecticut)
ABSTRACT Systems and methods for formal verification of programs. The systems and methods provide a new game-theoretical, strategy-based compositional semantic model for concurrency, a set of formal linking theorems for composing multithreaded and multicore concurrent layers, and a compiler that supports certified thread-safe compilation and linking. Verification of an overlay interface can include determining an intermediate strategy for a primitive operation running on an underlay interface and refining that intermediate strategy to a strategy running on the overlay interface by applying a vertical and a horizontal composition rule. The refined strategy can then be composed with compatible strategies running on the overlay interface according to a parallel composition rule. Strategies may be compatible when rely conditions imposed by each strategy satisfy guarantees provided by the other strategies. The system and method of formal verification can be applied to formal verification of smart contracts.
FILED Tuesday, July 12, 2022
APPL NO 17/862480
ART UNIT 2198 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/3608 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11816537 Monroe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) UNIVERSITY OF MARYLAND (College Park, Maryland);  DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S) University of Maryland (College Park, Maryland);  Duke University (Durham, North Carolina)
INVENTOR(S) Christopher Monroe (Ellicott City, Maryland);  Jungsang Kim (Chapel Hill, North Carolina)
ABSTRACT A modular quantum computer architecture is developed with a hierarchy of interactions that can scale to very large numbers of qubits. Local entangling quantum gates between qubit memories within a single modular register are accomplished using natural interactions between the qubits, and entanglement between separate modular registers is completed via a probabilistic photonic interface between qubits in different registers, even over large distances. This architecture is suitable for the implementation of complex quantum circuits utilizing the flexible connectivity provided by a reconfigurable photonic interconnect network. The subject architecture is made fault-tolerant which is a prerequisite for scalability. An optimal quantum control of multimode couplings between qubits is accomplished via individual addressing the qubits with segmented optical pulses to suppress crosstalk in each register, thus enabling high-fidelity gates that can be scaled to larger qubit registers for quantum computation and simulation.
FILED Friday, July 23, 2021
APPL NO 17/384574
ART UNIT 2896 — Computer Architecture and I/O
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/113 (20130101)

Electric Digital Data Processing
G06F 15/76 (20130101)
G06F 2015/768 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11816548 Verma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Dinesh C. Verma (New Castle, New York);  Supriyo Chakraborty (White Plains, New York)
ABSTRACT Embodiments of the invention are directed to a computer-implemented method of distributed learning using a fusion-based approach. The method includes determining data statistics at each system node of a plurality of system nodes, wherein each system node respectively comprises an artificial intelligence model. The method further includes determining a set of control and coordination instructions for training each artificial intelligence model at each system node of the plurality of system nodes. The method further includes directing an exchange of data between the plurality of system nodes based on the data statistics of each system node of the plurality of system nodes. The method further includes fusing trained artificial intelligence models from the plurality of system nodes into a fused artificial intelligence model, wherein the trained artificial intelligence models are trained using the set of control and coordination instructions.
FILED Tuesday, January 08, 2019
APPL NO 16/242045
ART UNIT 2125 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 20/10 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11816867 Jolliff
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Jason K. Jolliff (Slidell, Louisiana)
ABSTRACT Systems and methods are provided for color-enhancing satellite data in a manner that is specific to the true color ocean signal, i.e., the light that is emanating from the ocean surface. These color enhanced images, in turn, can be used as a scientific research and monitoring tool for studying the coastal ocean.
FILED Tuesday, February 16, 2021
APPL NO 17/176988
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/1021 (20130101)
B64G 2001/1028 (20130101)

Image Data Processing or Generation, in General
G06T 7/90 (20170101) Original (OR) Class
G06T 2207/10024 (20130101)
G06T 2207/10032 (20130101)

Pictorial Communication, e.g Television
H04N 9/67 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817204 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio);  The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Nathaniel Braman (Bethel Park, Pennsylvania);  Tristan Maidment (Cleveland, Ohio);  Yijiang Chen (Cleveland, Ohio)
ABSTRACT Embodiments discussed herein facilitate determination of whether lesions are benign or malignant. One example embodiment is a method, comprising: accessing medical imaging scan(s) that are each associated with distinct angle(s) and each comprise a segmented region of interest (ROI) of that medical imaging scan comprising a lesion associated with a first region and a second region; providing the first region(s) of the medical imaging scan(s) to trained first deep learning (DL) model(s) of an ensemble and the second region(s) of the medical imaging scan(s) to trained second DL model(s) of the ensemble; and receiving, from the ensemble of DL models, an indication of whether the lesion is a benign architectural distortion (AD) or a malignant AD.
FILED Wednesday, December 09, 2020
APPL NO 17/116366
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/025 (20130101)
A61B 6/469 (20130101)
A61B 6/502 (20130101)
A61B 6/5217 (20130101)

Electric Digital Data Processing
G06F 18/214 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101)
G06T 2207/10112 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30068 (20130101)
G06T 2207/30096 (20130101)

Image or Video Recognition or Understanding
G06V 10/25 (20220101)
G06V 10/82 (20220101)
G06V 10/764 (20220101)
G06V 2201/03 (20220101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101) Original (OR) Class
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817232 Ganguli et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Sabyasachi Ganguli (Beavercreek, Ohio);  Ajit K Roy (Beavercreek, Ohio);  Chenggang Chen (Beavercreek, Ohio)
ABSTRACT An electrically conductive, flexible, strain resilient product is produced by mixing metal coated carbon nanotube networks with a liquid polymeric resin to produce a liquid mixture, and the mixture is cured to produce the product. The networks may include welded junctions between nanotubes formed by depositing and melting metal nanoparticles on the nanotubes to form the metal coating. After the mixing step the liquid mixture may be deposited on a flexible substrate in the form of an electrical circuit. The mixing step may further include mixing the composite with a volatile solvent to produce a selected viscosity. Then, a three-dimensional printer may be used to print the product, such as an electrical circuit, on a substrate. The product is cured in an atmosphere that absorbs the solvent. The conductivity of the mixture may be adjusted by adjusting the weight percentage of the metal coated carbon nanotube networks from 50% to 90%, but a preferred range is between 75% and 85%.
FILED Tuesday, March 15, 2022
APPL NO 17/695144
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/18 (20220101)
B22F 1/18 (20220101)
B22F 1/18 (20220101)
B22F 1/107 (20220101)
B22F 1/107 (20220101)
B22F 3/02 (20130101)
B22F 10/18 (20210101)
B22F 2302/403 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Alloys
C22C 2026/002 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817240 Jonker
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Berend T Jonker (Waldorf, Maryland)
ABSTRACT The invention relates to heterostructures including a layer of a two-dimensional material placed on a multiferroic layer. An ordered array of differing polarization domains in the multiferroic layer produces corresponding domains having differing properties in the two-dimensional material. When the multiferroic layer is ferroelectric, the ferroelectric polarization domains in the layer produce local electric fields that penetrate the two-dimensional material. The local electric fields can influence properties of the two-dimensional material, including carrier density, transport properties, optical properties, surface chemistry, piezoelectric-induced strain, magnetic properties, and interlayer spacing. Methods for producing the heterostructures are provided. Devices incorporating the heterostructures are also provided, including tunable sensors, optical emitters, and programmable logic gates.
FILED Monday, March 22, 2021
APPL NO 17/208756
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/414 (20130101)
G01N 27/4146 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/009 (20130101) Original (OR) Class
H01F 10/1933 (20130101)
H01F 10/3222 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/24 (20130101)
H01L 29/778 (20130101)
H01L 29/1606 (20130101)
H01L 29/7391 (20130101)
H01L 29/66984 (20130101)
H01L 29/78391 (20140902)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817318 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Travis J. Anderson (Alexandria, Virginia);  James C. Gallagher (Alexandria, Virginia);  Marko J. Tadjer (Vienna, Virginia);  Alan G. Jacobs (Arlington, Virginia);  Boris N. Feigelson (Springfield, Virginia)
ABSTRACT A method for activating implanted dopants and repairing damage to dopant-implanted GaN to form n-type or p-type GaN. A GaN substrate is implanted with n- or p-type ions and is subjected to a high-temperature anneal to activate the implanted dopants and to produce planar n- or p-type doped areas within the GaN having an activated dopant concentration of about 1018-1022 cm−3. An initial annealing at a temperature at which the GaN is stable at a predetermined process temperature for a predetermined time can be conducted before the high-temperature anneal. A thermally stable cap can be applied to the GaN substrate to suppress nitrogen evolution from the GaN surface during the high-temperature annealing step. The high-temperature annealing can be conducted under N2 pressure to increase the stability of the GaN. The annealing can be conducted using laser annealing or rapid thermal annealing (RTA).
FILED Wednesday, March 01, 2023
APPL NO 18/116000
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/266 (20130101)
H01L 21/3245 (20130101)
H01L 21/26546 (20130101) Original (OR) Class
H01L 21/28575 (20130101)
H01L 29/36 (20130101)
H01L 29/207 (20130101)
H01L 29/452 (20130101)
H01L 29/2003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817831 Wagner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
ASSIGNEE(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S) Eric C. Wagner (Redondo Beach, California);  Timothy R. LaRocca (Redondo Beach, California)
ABSTRACT A radio frequency (RF) summer circuit having a characteristic impedance Z0 comprises first and second ports coupled by first and second resistances, respectively, to a junction. The circuit further comprises a series combination of a third resistance and a switch movable between open and closed positions and an amplifier having input and output terminals and operable in an off state and an on state wherein the series combination is coupled across the input and output terminals of the amplifier between the junction and a third port. The first resistance, second resistance, and the third resistance are all substantially equal to Z0/3. Further, when the switch is moved to the closed position and the amplifier is switched to the off state a passive mode of operation is implemented and when the switch is moved to the open position and the amplifier is switched to the on state an active mode of operation is implemented. The RF summer circuit develops a summed signal at the third port equal to a sum of signals at the first and second ports modified by one of first and second gain values.
FILED Monday, February 27, 2023
APPL NO 18/114401
ART UNIT 2843 — Electrical Circuits and Systems
CURRENT CPC
Amplifiers
H03F 1/56 (20130101)
H03F 3/72 (20130101)
H03F 3/195 (20130101) Original (OR) Class
H03F 2200/451 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817879 Djordjevic et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Ivan B. Djordjevic (Tucson, Arizona);  Xiaole Sun (Tucson, Arizona)
ABSTRACT Disclosed are systems, methods, and software for generating spatially-coupled low-density parity-check (SC-LDPC) codes. A method for generating SC-LDPC codes includes generating one or more quasi-cyclic low-density parity-check (QC-LDPC) codes, and also includes assigning at least one of the generated one or more QC-LDPC codes as one or more template codes. The method further includes copying at least a portion of the one or more template codes to introduce irregularity. The method also includes shifting one or more template codes on a sub-block basis to generate at least one SC-LDPC code. As compared to known LDPC code generation modalities, the disclosed invention provides a simplified technique for implementation in streamlined hardware which has more general applicability across both present, and anticipated, communication systems, including those adapted for use with optical communications, wireless communications, and 5G as well as future 6G.
FILED Friday, June 26, 2020
APPL NO 17/621639
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 13/116 (20130101) Original (OR) Class
H03M 13/616 (20130101)
H03M 13/1154 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11818145 Pan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
Mitigating APT Reasoning with Provenance in Large Enterprise Networks (MARPLE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Xiaorui Pan (San Jose, California);  Xiaokui Shu (Ossining, New York);  Dhilung Hang Kirat (White Plains, New York);  Jiyong Jang (White Plains, New York);  Marc Philippe Stoecklin (White Plains, New York)
ABSTRACT An automated technique for security monitoring leverages a labeled semi-directed temporal graph derived from system-generated events. The temporal graph is mined to derive process-centric subgraphs, with each subgraph consisting of events related to a process. The subgraphs are then processed to identify atomic operations shared by the processes, wherein an atomic operation comprises a sequence of system-generated events that provide an objective context of interest. The temporal graph is then reconstructed by substituting the identified atomic operations derived from the subgraphs for the edges in the original temporal graph, thereby generating a reconstructed temporal graph. Using graph embedding, the reconstructed graph is converted into a representation suitable for further machine learning, e.g., using a deep neural network. The network is then trained to learn the intention underlying the temporal graph. The approach operates to understand running behavior of programs, to classify them, and then enable detection of potential malicious behaviors.
FILED Monday, December 09, 2019
APPL NO 16/706926
ART UNIT 2434 — Cryptography and Security
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 3/08 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1416 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11812966 Dreilinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) NeuraMedica Inc. (Oregon City, Oregon)
ASSIGNEE(S) NeuraMedica Inc. (Oregon City, Oregon)
INVENTOR(S) Rachel Dreilinger (Beavercreek, Oregon);  Neil Roundy (Eugene, Oregon);  Mariah Knight (Cornelius, Oregon);  Sandra Baker (Tigard, Oregon)
ABSTRACT A medical device forming method, an applier for manipulating clips, and a cartridge for holding clips are disclosed herein.
FILED Friday, April 24, 2020
APPL NO 16/858546
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/083 (20130101) Original (OR) Class
A61B 17/1222 (20130101)
A61B 2017/0488 (20130101)
A61B 2017/00584 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813037 Melodia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Research Foundation for The State University of New York (Amherst, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Amherst, New York)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Giuseppe Enrico Santagati (Cambridge, Massachusetts);  Laura Galluccio (Trecastagni, Italy);  Sergio Palazzo (San Giovanni la Punta, Italy)
ABSTRACT Methods and devices for transmitting and receiving data through biological tissue using ultrasonic pulses are described. Methods of the present invention may set an initial time-hopping frame length and an initial spreading code length for data transmission. A request-to-transmit may be sent from a transmitter over a control channel at the initial frame and code length. The receiver may respond to the transmitter with a clear-to-transmit packet having feedback information. The feedback information can be used to improve a forward time-hopping frame length and a forward spreading code length. Embodiments of the invention may involve a body area network or body surface network comprising a plurality of implanted sensor nodes operating according to the disclosed invention.
FILED Monday, January 25, 2021
APPL NO 17/157251
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0015 (20130101)
A61B 5/021 (20130101)
A61B 5/0024 (20130101)
A61B 5/024 (20130101)
A61B 5/026 (20130101)
A61B 5/0028 (20130101) Original (OR) Class
A61B 5/0031 (20130101)
A61B 5/0816 (20130101)
A61B 5/14532 (20130101)
A61B 5/14542 (20130101)

Transmission Systems for Measured Values, Control or Similar Signals
G08C 23/02 (20130101)

Transmission
H04B 1/71635 (20130101)
H04B 2001/6908 (20130101)

Selecting
H04Q 9/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813054 Dawson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Geospatial Intelligence Agency (NGA)
National Science Foundation (NSF)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Geraldine Dawson (Durham, North Carolina);  Guillermo Sapiro (Durham, North Carolina);  Jordan Hashemi (Durham, North Carolina)
ABSTRACT The subject matter described herein includes methods, systems, and computer readable media for conducting an automatic assessment of postural control of a subject. According to one aspect, a method occurs at a computing platform including a processor and memory. The method includes displaying a stimulus to which a subject responds, capturing facial image data of the subject, analyzing the facial image data to determine a frequency of head displacement information associated with the subject, using the head displacement information to derive postural control assessment data, and determining that the postural control assessment data is indicative of a neurodevelopmental or neuropsychiatric disorder associated with the subject.
FILED Friday, November 08, 2019
APPL NO 16/678828
ART UNIT 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1116 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 3/012 (20130101)
G06F 3/017 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/70 (20170101)
G06T 2207/30201 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813056 Singamaneni et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Dental and Craniofacial Research (NIDCR)
National Science Foundation (NSF)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Srikanth Singamaneni (St. Louis, Missouri);  Zheyu Wang (St. Louis, Missouri);  Jingyi Luan (St. Louis, Missouri)
ABSTRACT The present disclosure is directed to microneedle patches for direct sampling and ultrasensitive detection of protein biomarkers in dermal interstitial fluids. The microneedle patches are comprised of polymers with high protein absorption capability (e.g. polystyrene) and are modified with capture biorecognition elements that are specific to target analytes in the interstitial fluid (ISF). Systems and methods are further provided for detection of a target ISF analyte obtained by in vivo sampling of the ISF using a microneedle patch.
FILED Thursday, July 30, 2020
APPL NO 16/943157
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/14514 (20130101) Original (OR) Class

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0021 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0015 (20130101)
A61M 2037/0061 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5306 (20130101)
G01N 33/6869 (20130101)
G01N 33/54386 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813184 Sicotte et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ZENFLOW, INC. (San Francisco, California)
ASSIGNEE(S) ZENFLOW, INC. (San Francisco, California)
INVENTOR(S) Marcel Song Sicotte (San Francisco, California);  Shreya Mehta (San Francisco, California);  Austin Michael Bly (San Clemente, California);  Ronald J. Jabba (Redwood City, California)
ABSTRACT Benign prosthetic hyperplasia (BPH) is a non-cancerous enlargement of the prostate gland. Treatment options for BPH include medication, surgery (e.g., removal of enlarged prostate tissue), and minimally invasive procedures (e.g., needle ablation, electrovaporization, thermotherapy, and stent insertion). Minimally invasive procedure is typically the preferred choice if medication is ineffective. Accordingly, disclosed herein are system and method for treating BPH using improved implant and delivery device. Certain embodiments of the delivery device can include: a camming barrel having a first groove at the distal end of the camming barrel; a sheath, located within a lumen of the camming barrel, for storing the implantable device; and a first cam follower coupled to the sheath.
FILED Wednesday, February 17, 2021
APPL NO 17/177772
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/3468 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/885 (20130101)
A61F 2/966 (20130101) Original (OR) Class
A61F 2/9517 (20200501)
A61F 2002/048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813262 Sivathanu et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Vivek Sivathanu (Cambridge, Massachusetts);  Roger Dale Kamm (Cambridge, Massachusetts)
ABSTRACT Provided herein are methods and compositions for increasing muscle strength, and for treating muscle wasting disorders, muscle degenerative disease, or exercise-induced weakness, and cancer.
FILED Friday, November 02, 2018
APPL NO 16/761100
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/496 (20130101)
A61K 31/506 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 21/06 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813592 Li et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
APPLICANT(S) North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S) North Carolina State University (Raleigh, North Carolina)
INVENTOR(S) Fanxing Li (Raleigh, North Carolina);  Luke Michael Neal (Raleigh, North Carolina);  Yunfei Gao (Raleigh, North Carolina);  Seif Yusuf (Raleigh, North Carolina);  Ryan Dudek (Raleigh, North Carolina)
ABSTRACT Redox catalysts having surface medication, methods of making redox catalysts with surface modification, and uses of the surface modified redox catalysts are provided. In some aspects, the redox catalysts include a core oxygen carrier region such as CaMnO3, BaMnO3−δ, SrMnO3−δ, Mn2SiO4, Mn2MgO4−δ, La0.8Sr0.2O3−δ, La0.8Sr0.2FeO3−δ, Ca9Ti0.1Mn0.9O3−δ, Pr6O11−δ, manganese ore, or a combination thereof; and an outer shell having an average thickness of about 1-100 monolayers surrounding the outer surface of the core region. The outer shell can include, for example a salt selected such as Li2WO4, Na2WO4, K2WO4, SrWO4, Li2MoO4, Na2MoO4, K2MoO4, CsMoO4, Li2CO3, Na2CO3, K2CO3, or a combination thereof.
FILED Thursday, June 14, 2018
APPL NO 16/622627
ART UNIT 1738 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/14 (20130101)
B01J 23/002 (20130101) Original (OR) Class
B01J 23/02 (20130101)
B01J 23/005 (20130101)
B01J 23/30 (20130101)
B01J 23/34 (20130101)
B01J 35/002 (20130101)
B01J 35/0006 (20130101)
B01J 35/10 (20130101)
B01J 37/06 (20130101)
B01J 37/12 (20130101)
B01J 37/16 (20130101)
B01J 37/0081 (20130101)
B01J 37/088 (20130101)
B01J 37/0215 (20130101)

Acyclic or Carbocyclic Compounds
C07C 4/06 (20130101)
C07C 5/48 (20130101)
C07C 11/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813594 Li et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Christina W. Li (Lafayette, Indiana);  Alexander J. Shumski (Bethel Park, Pennsylvania);  William A. Swann (West Lafayette, Indiana)
ABSTRACT A heterogeneous catalyst for substrate-directed hydrogenation includes bimetallic nanoparticles of M1-M2, wherein M1 is a noble metal and M2 is a first-row transition metal. The bimetallic nanoparticles are on a substrate and atoms of both the noble metal and the first-row transition metal are distributed across surfaces of the bimetallic nanoparticles. The heterogeneous catalyst may be produced by providing M1-M2 bimetallic nanoparticles on a substrate to produce an intermediate composition, and performing a reduction process on the intermediate composition such that atoms of both the noble metal (M1) and the first-row transition metal (M2) are distributed across surfaces of the bimetallic nanoparticles and thereby form the heterogeneous catalyst. The catalyst may be used for performing directed hydrogenation of a substrate.
FILED Tuesday, January 11, 2022
APPL NO 17/572909
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/04 (20130101)
B01J 21/08 (20130101)
B01J 23/892 (20130101)
B01J 23/8913 (20130101)
B01J 23/8926 (20130101) Original (OR) Class
B01J 35/006 (20130101)
B01J 37/08 (20130101)
B01J 37/0201 (20130101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/07 (20130101)

Acyclic or Carbocyclic Compounds
C07C 29/172 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813829 Ma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Ruilong Ma (Atlanta, Georgia);  Vladimirv V. Tsukruk (Atlanta, Georgia)
ABSTRACT In a method for making a flexible material, a sheet of graphene oxide-composite paper is subjected to an environment having a relative humidity above a predetermined threshold for a predetermined amount of time. At least one expansion cut is cut in the sheet of graphene oxide-composite paper. A flexible conductive material includes a sheet of graphene oxide-composite paper defining at least one cut passing therethrough and formed it a kirigami structure. A region of the sheet of graphene oxide-composite paper includes reduced graphene oxide.
FILED Wednesday, July 10, 2019
APPL NO 16/507479
ART UNIT 1783 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 29/02 (20130101)
B32B 29/06 (20130101) Original (OR) Class
B32B 2264/102 (20130101)
B32B 2457/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Electric Machines Not Otherwise Provided for
H02N 1/04 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/30 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814009 Shin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan);  THE UNIVERSITY OF COLORADO (Denver, Colorado)
INVENTOR(S) Kang G. Shin (Ann Arbor, Michigan);  Liang He (Denver, Colorado)
ABSTRACT A driving authentication system is presented for a vehicle. The system includes: a dongle interfaced with a battery of the vehicle and an authenticator configured to receive a discharge current from the battery. The dongle operates to modulate discharge current from the battery with an input code; and the authenticator demodulate the input code from the discharge current, compares the input code to the one or more known authentication codes and, in response to the input code matching one of the one or more known authentication codes, controls power capacity of the battery.
FILED Thursday, March 24, 2022
APPL NO 17/703346
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for
B60R 25/04 (20130101)
B60R 25/23 (20130101) Original (OR) Class
B60R 25/1001 (20130101)

Starting of Combustion Engines; Starting Aids for Such Engines, Not Otherwise Provided for
F02N 11/087 (20130101)
F02N 11/0862 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814285 McFarland et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Eric W. McFarland (Santa Barbara, California);  Ches Upham (Menlo Park, California);  Jiren Zeng (Goleta, California);  Clarke Palmer (Goleta, California);  Shizhao Su (Santa Barbara, California);  Davide Mannini (Santa Barbara, California);  Dohyung Kang (Goleta, California);  Nazanin Rahimi (Goleta, California);  Horia Metiu (Santa Barbara, California);  Michael Gordon (Goleta, California)
ABSTRACT The reaction rate of hydrocarbon pyrolysis can be increased to produce solid carbon and hydrogen by the use of molten materials which have catalytic functionality to increase the rate of reaction and physical properties that facilitate the formation and contamination-free separation of the solid carbon. Processes, materials, reactor configurations, and conditions are disclosed whereby methane and other hydrocarbons can be decomposed at high reaction rates into hydrogen gas and carbon products without any carbon oxides in a single reaction step. The process also makes use of specific properties of selected materials with unique solubilities and/or wettability of products into (and/or by) the molten phase to facilitate generation of purified products and increased conversion in more general reactions.
FILED Friday, November 16, 2018
APPL NO 16/764226
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 8/0278 (20130101)
B01J 23/825 (20130101)
B01J 23/8437 (20130101)
B01J 27/08 (20130101)
B01J 35/0006 (20130101)
B01J 35/12 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/26 (20130101) Original (OR) Class
C01B 2203/0277 (20130101)
C01B 2203/1011 (20130101)
C01B 2203/1058 (20130101)
C01B 2203/1241 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814321 Wang
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (Tuscaloosa, Alabama)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (Tuscaloosa, Alabama)
INVENTOR(S) Jialai Wang (Tuscaloosa, Alabama)
ABSTRACT Cementitious compositions comprising a hydraulic cementitious material, a compound selected from the group consisting of a polyhydroxy aromatic compound, a polycarboxylic acid-containing compound or a salt thereof, ascorbic acid or a salt thereof, or a combination thereof, and a particulate material or a water soluble silicate-containing material that interacts with the compound are described herein. The polyhydroxy aromatic compound can be a water soluble compound having from two to thirty hydroxyl groups. The particulate material can exhibit a particle size distribution, wherein at least about 90% by weight of the particles have a diameter of less than 2 mm. Suitable particulate materials include nanoparticles and microparticles. The cementitious compositions can be used to form building materials. The cementitious compositions are especially suited for inhibiting corrosion of reinforcing steel bars embedded in concrete mixtures. Methods of making and using the cementitious composition are also disclosed.
FILED Friday, July 30, 2021
APPL NO 17/390184
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 14/005 (20130101)
C04B 24/02 (20130101)
C04B 24/06 (20130101) Original (OR) Class
C04B 28/04 (20130101)
C04B 28/24 (20130101)
C04B 28/26 (20130101)
C04B 28/188 (20130101)
C04B 40/0046 (20130101)
C04B 2103/22 (20130101)
C04B 2111/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814396 Dai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana);  University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana);  University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Mingji Dai (Alpharetta, Georgia);  Dexter Cameron Davis (Watertown, Massachusetts);  Alexander Adibekian (Palm City, Florida);  Dominic Gregor Hoch (Jupiter, Florida);  Zhong-Yin Zhang (West Lafayette, Indiana)
ABSTRACT The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.
FILED Monday, May 03, 2021
APPL NO 17/246775
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 493/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814462 Veige
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Adam S. Veige (Gainesville, Florida)
ABSTRACT The disclosure provides a method of preparing a functionalized cyclic polymer the method including reacting a metal-alkylidyne compound, metallacycloalkylene compound, or metallacyclopentadiene compound with a plurality of alkynes to form the functionalized cyclic polymer, wherein at least one alkyne comprises a functional group capable of further reacting to form a modified polymer. Also provided is a stereoregular functionalized cyclic polymer prepared by the method of the disclosure.
FILED Monday, November 01, 2021
APPL NO 17/516191
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 4/78 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814562 Jákli et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Kent State University (Kent, Ohio);  The University of Akron (Akron, Ohio)
ASSIGNEE(S) KENT STATE UNIVERSITY (Kent, Ohio);  THE UNIVERSITY OF AKRON (Akron, Ohio)
INVENTOR(S) Antal Jákli (Kent, Ohio);  Chenrun Feng (Kent, Ohio);  Chathuranga Prageeth Hemantha Rajapaksha (Kent, Ohio);  Vikash Kaphle (Kent, Ohio);  Thein Kyu (Akron, Ohio)
ABSTRACT An ionic liquid crystal elastomer composition includes a liquid crystal elastomer; and an ionic liquid.
FILED Monday, January 11, 2021
APPL NO 17/248127
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 2/14 (20130101)
C08F 2/50 (20130101)
C08F 20/30 (20130101)
C08F 22/20 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/07 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 19/02 (20130101) Original (OR) Class
C09K 19/542 (20130101)
C09K 2019/0448 (20130101)
C09K 2019/546 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814564 Bleszynski
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Denver (Denver, Colorado)
ASSIGNEE(S) University of Denver (Denver, Colorado)
INVENTOR(S) Monika Bleszynski (Denver, Colorado)
ABSTRACT Methods, compounds, and compositions for inhibiting ice nucleation are disclosed. A method includes selecting a modified polyvinyl alcohol molecule based on at least one altered hydroxyl distance of the modified polyvinyl alcohol molecule and applying the modified polyvinyl alcohol molecule to water molecules to inhibit ice nucleation when subjected to freezing temperatures.
FILED Friday, May 07, 2021
APPL NO 17/314402
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 216/06 (20130101)

Compositions of Macromolecular Compounds
C08L 29/04 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 3/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814644 Boeke et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Jef D. Boeke (New York, New York);  Leslie A. Mitchell (New York, New York);  Neta Agmon (New York, New York)
ABSTRACT Compositions, methods and kits are provided. The compositions, methods and kits are for assembly of series of DNA segments in yeast using homologous recombination. The assembled DNA segments are maintained episomally. Yeast made using the methods are included, as are methods of using the yeast to express proteins, and for screening test agents that can affect yeast that are modified to include the assembled DNA segments.
FILED Friday, July 07, 2017
APPL NO 16/315844
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/16 (20130101)
C12N 15/64 (20130101)
C12N 15/65 (20130101)
C12N 15/66 (20130101)
C12N 15/81 (20130101)
C12N 15/85 (20130101)
C12N 15/90 (20130101)
C12N 15/905 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814655 Barnes et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) DNA POLYMERASE TECHNOLOGY, INC. (St. Louis, Missouri)
ASSIGNEE(S) DNA POLYMERASE TECHNOLOGY, INC. (St. Louis, Missouri)
INVENTOR(S) Wayne M. Barnes (University City, Missouri);  Milko B. Kermekchiev (St. Louis, Missouri);  Zhian Zhang (Ballwin, Missouri)
ABSTRACT Provided are mutant polymerases having DNA polymerase activity and reverse transcriptase activity or strand displacement activity, along with target nucleic acid amplification methods employing such mutant polymerases.
FILED Friday, May 28, 2021
APPL NO 17/303445
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1252 (20130101) Original (OR) Class
C12N 9/1276 (20130101)
C12N 15/1096 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6846 (20130101)
C12Q 1/6846 (20130101)
C12Q 2521/101 (20130101)
C12Q 2521/101 (20130101)
C12Q 2521/107 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/119 (20130101)
C12Q 2531/119 (20130101)

Enzymes
C12Y 207/07007 (20130101)
C12Y 207/07049 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814701 Vo et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) NanoAL LLC (Ashland, Massachusetts)
ASSIGNEE(S) NanoAL LLC (Ashland, Massachusetts)
INVENTOR(S) Nhon Q. Vo (Winchester, Massachusetts);  Francisco U. Flores (Lowell, Massachusetts);  Davaadorj Bayansan (Glenview, Illinois);  Evander Ramos (Los Angeles, California)
ABSTRACT Aluminum-magnesium-manganese-zirconium-inoculant alloys that exhibit high strength, good ductility, high creep resistance, high thermal stability and durability.
FILED Friday, September 06, 2019
APPL NO 16/562981
ART UNIT 1738 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages
B65D 1/12 (20130101)

Alloys
C22C 21/08 (20130101) Original (OR) Class

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/047 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815142 Wellborn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Science Foundation (NSF)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) Patrick Wellborn (Nashville, Tennessee);  Jason Mitchell (Nashville, Tennessee);  Robert Webster, III (Nashville, Tennessee)
ABSTRACT This disclosure relates to a magnetorheological (MR) brake. The MR brake includes a rotor constructed at least partially of a ferromagnetic material, and a housing that supports the rotor such that the rotor and the housing are rotatable relative to each other about an axis, wherein the housing and rotor are configured such that a fluid gap is defined between the housing and the rotor, and wherein portions of the housing adjacent the rotor are constructed at least partially of a ferromagnetic material. An MR fluid is disposed in the fluid gap. A current-carrying coil is excitable to generate a magnetic field within ferromagnetic portions of the rotor and the housing and acts on the MR fluid. At least one element constructed of a material having low magnetic permeability is configured route the lines of magnetic flux through surrounding higher permeability material on opposite sides of the fluid gap.
FILED Monday, February 03, 2020
APPL NO 17/428052
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Couplings for Transmitting Rotation; Clutches; Brakes
F16D 57/002 (20130101) Original (OR) Class
F16D 2121/20 (20130101)
F16D 2131/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815506 Khismatullin et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Administrators of the Tulane Educational Fund (New Orleans, Louisiana)
ASSIGNEE(S) THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana)
INVENTOR(S) Damir Khismatullin (New Orleans, Louisiana);  Daishen Luo (Metairie, Louisiana)
ABSTRACT The disclosed apparatus, systems and methods relate to ATPA technology that provides a method for the real-time assessment of the polymerization of a sample, e.g., whole blood or blood plasma coagulation, by a non-contact acoustic tweezing device. The acoustic tweezing technology integrates photo-optical tests used in plasma coagulation assays with mechanical (viscoelastic) tests used in whole blood analysis. Its key disruptive features are the increased reliability and accuracy due to non-contact measurement, low sample volume requirement, relatively short procedure time (less than 10 minutes), and the ability to assess the level of Factor XIII function from measurements of the fibrin network formation time.
FILED Tuesday, October 27, 2020
APPL NO 17/081213
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/82 (20130101)
G01N 21/272 (20130101)
G01N 33/86 (20130101)
G01N 33/4905 (20130101) Original (OR) Class
G01N 2021/1721 (20130101)
G01N 2021/1725 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11816018 Shao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Zhong Shao (Branford, Connecticut);  Ronghui Gu (New Haven, Connecticut);  Vilhelm Sjoberg (New Haven, Connecticut);  Jieung Kim (New Haven, Connecticut);  Jeremie Koenig (New Haven, Connecticut)
ABSTRACT Systems and methods for formal verification of programs. The systems and methods provide a new game-theoretical, strategy-based compositional semantic model for concurrency, a set of formal linking theorems for composing multithreaded and multicore concurrent layers, and a compiler that supports certified thread-safe compilation and linking. Verification of an overlay interface can include determining an intermediate strategy for a primitive operation running on an underlay interface and refining that intermediate strategy to a strategy running on the overlay interface by applying a vertical and a horizontal composition rule. The refined strategy can then be composed with compatible strategies running on the overlay interface according to a parallel composition rule. Strategies may be compatible when rely conditions imposed by each strategy satisfy guarantees provided by the other strategies. The system and method of formal verification can be applied to formal verification of smart contracts.
FILED Tuesday, July 12, 2022
APPL NO 17/862480
ART UNIT 2198 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/3608 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11816558 Lathrop et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Division of Earth Sciences (EAR)
APPLICANT(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
INVENTOR(S) Daniel Lathrop (University Park, Maryland);  Itamar Shani (Rockville, Maryland);  Peter Megson (Washington, District of Columbia);  Alessandro Restelli (Greenbelt, Maryland);  Anthony Robert Mautino (Damascus, Maryland)
ABSTRACT An integrated circuit device for reservoir computing can include a weighted input layer, an unweighted, asynchronous, internal recurrent neural network made up of nodes having binary weighting, and a weighted output layer. Weighting of output signals can be performed using predetermined weighted sums stored in memory. Application specific integrated circuit (ASIC) embodiments may include programmable nodes. Characteristics of the reservoir of the device can be tunable to perform rapid processing and pattern recognition of signals at relatively large rates.
FILED Wednesday, May 16, 2018
APPL NO 16/613990
ART UNIT 2484 — Recording and Compression
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/044 (20230101)
G06N 3/063 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11816907 Fathi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Pointivo, Inc. (Atlanta, Georgia)
ASSIGNEE(S) POINTIVO, INC. (Atlanta, Georgia)
INVENTOR(S) Habib Fathi (Atlanta, Georgia);  Miguel M. Serrano (Marietta, Georgia);  Bradden John Gross (Atlanta, Georgia);  Daniel L. Ciprari (Atlanta, Georgia)
ABSTRACT Examples of various method and systems are provided for information extraction from scene information. 2D image information can be generated from 2D images of the scene that are overlapping at least part of one or more object(s). The 2D image information can be combined with 3D information about the scene incorporating at least part of the object(s) to generate projective geometry information. Clustered 3D information associated with the object(s) can be generated by partitioning and grouping 3D data points present in the 3D information. The clustered 3D information can be used to provide, e.g., measurement information, dimensions, geometric information, and/or topological information about the object(s). Segmented 2D information can also be generated from the 2D image information. Validated 2D and 3D information can be produced by cross-referencing between the projective geometry information, clustered 3D information, and/or segmented 2D image information, and used to label the object(s) in the scene.
FILED Monday, February 07, 2022
APPL NO 17/665653
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 18/23 (20230101)

Image Data Processing or Generation, in General
G06T 7/55 (20170101)
G06T 17/00 (20130101)
G06T 2207/10028 (20130101)

Image or Video Recognition or Understanding
G06V 20/10 (20220101)
G06V 20/64 (20220101)
G06V 20/70 (20220101) Original (OR) Class
G06V 20/647 (20220101)
G06V 2201/12 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817524 Welser et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Magnolia Optical Technologies, Inc. (Woburn, Massachusetts)
ASSIGNEE(S) Magnolia Optical Technologies, Inc. (Woburn, Massachusetts)
INVENTOR(S) Roger E. Welser (Providence, Rhode Island);  Ashok K. Sood (Brookline, Massachusetts)
ABSTRACT Refractive optical element designs are provided for high geometric optical efficiency over a wide range of incident angles. To minimize Fresnel reflection losses, the refractive optical element designs employ multiple encapsulant materials, differing in refractive index. Concentrator photovoltaic subassemblies are formed by embedding a high efficiency photovoltaic device within the refractive optical element, along with appropriate electrical contacts and heat sinks. Increased solar electric power output is obtained by employing a single-junction III-V material structure with light-trapping structures.
FILED Monday, November 15, 2021
APPL NO 17/526623
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/115 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/048 (20130101)
H01L 31/056 (20141201)
H01L 31/065 (20130101)
H01L 31/184 (20130101)
H01L 31/186 (20130101)
H01L 31/0203 (20130101)
H01L 31/0232 (20130101)
H01L 31/0445 (20141201)
H01L 31/0481 (20130101)
H01L 31/0543 (20141201)
H01L 31/0547 (20141201)
H01L 31/0725 (20130101)
H01L 31/0735 (20130101)
H01L 31/1844 (20130101)
H01L 31/1884 (20130101) Original (OR) Class
H01L 31/02165 (20130101)
H01L 31/02168 (20130101)
H01L 31/03046 (20130101)
H01L 31/022425 (20130101)
H01L 31/022475 (20130101)
H01L 31/035236 (20130101)
H01L 31/035263 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
Y02E 10/52 (20130101)
Y02E 10/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817588 Panat et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania);  The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania);  The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Rahul Panat (Pittsburgh, Pennsylvania);  Jie Li (Katy, Texas);  Jonghyun Park (Rolla, Missouri);  Mohammad Sadeq Saleh (Pittsburgh, Pennsylvania)
ABSTRACT Provided here is a method of manufacturing a lattice electrode useful in an energy storage device such as a battery or capacitor. A lattice electrode useful in an energy storage device such as a battery or capacitor also is provided, along with energy storage devices such as batteries or capacitors.
FILED Friday, October 04, 2019
APPL NO 16/593622
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/26 (20130101)
H01G 11/50 (20130101)
H01G 11/56 (20130101)
H01G 11/68 (20130101)
H01G 11/70 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/80 (20130101) Original (OR) Class
H01M 4/483 (20130101)
H01M 4/525 (20130101)
H01M 4/661 (20130101)
H01M 4/663 (20130101)
H01M 4/664 (20130101)
H01M 4/5825 (20130101)
H01M 10/0568 (20130101)
H01M 2004/021 (20130101)
H01M 2004/025 (20130101)
H01M 2004/028 (20130101)
H01M 2300/0017 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11818479 Wang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Rongrong Wang (East Lansing, Michigan);  He Lyu (East Lansing, Michigan)
ABSTRACT A technique is presented for quantizing pixels of an image using Sigma Delta quantization. In one aspect, pixel values for an image are segmented into columns of pixel values; and for each column in the matrix, pixel values of a given column are quantized using sigma delta modulation. The pixel values in a given column are preferably quantized as a whole, thereby minimizing accumulated quantization error from a starting pixel value in the given column to a current pixel value in the given column. In another aspect, the pixels of an image are quantized using a 2D generalization of Sigma Delta modulation.
FILED Friday, May 14, 2021
APPL NO 17/320700
ART UNIT 2698 — Selective Visual Display Systems
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 1/12 (20130101)
H03M 3/458 (20130101)

Pictorial Communication, e.g Television
H04N 25/70 (20230101) Original (OR) Class
H04N 25/75 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11813320 Rieder et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Agriculture (USDA)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia);  THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia);  THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
INVENTOR(S) Aida E. Rieder (Westbrook, Connecticut);  Teresa B. De Los Santos (Miller Place, New York);  Luis L. Rodriguez (Clinton, Connecticut);  Devendra Rai (Old Saybrook, Connecticut);  Fayna C. Diaz-San Segundo (Ronkonkoma, New York);  Paul D. Hoeprich (Pleasanton, California)
ABSTRACT Genetically engineered Foot and Mouth Disease Virus (FMDV) and related engineered proteins and polynucleotides, nanolipoprotein particles, compositions, methods and systems are described. The genetically engineered FMDV is modified by the strategic insertion of a protein tag into select regions of the FMDV genome which encode viral proteins that are exposed on the surface of the FMDV viral capsid. The inserted protein tag is displayed as a decoration or attachment on the viral capsid surface.
FILED Tuesday, February 16, 2021
APPL NO 17/176989
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/135 (20130101) Original (OR) Class
A61K 2039/5254 (20130101)
A61K 2039/55555 (20130101)
A61K 2039/55566 (20130101)
A61K 2039/55572 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/32122 (20130101)
C12N 2770/32134 (20130101)
C12N 2770/32141 (20130101)
C12N 2770/32162 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/70 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813582 Pang et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Simon Hoching Pang (Fremont, California);  Melinda Lia Wah Jue (Livermore, California)
ABSTRACT A resin includes a functionalized aminopolymer having amine sites for capturing carbon dioxide molecules, where each aminopolymer molecule has at least one functional group amenable to crosslinking, a porogen, and a crosslinking initiator. A product includes an aminopolymer material formed into a self-supporting structure, the aminopolymer material including crosslinked aminopolymers having amine sites for the capture of carbon dioxide molecules.
FILED Tuesday, July 06, 2021
APPL NO 17/368598
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/62 (20130101)
B01D 53/81 (20130101)
B01D 53/96 (20130101)
B01D 2253/34 (20130101)
B01D 2253/202 (20130101)
B01D 2257/504 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/267 (20130101) Original (OR) Class
B01J 20/3064 (20130101)
B01J 20/3085 (20130101)
B01J 20/3425 (20130101)
B01J 20/3483 (20130101)
B01J 20/3491 (20130101)
B01J 20/28033 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/50 (20170801)
C01B 2210/0007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813592 Li et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
APPLICANT(S) North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S) North Carolina State University (Raleigh, North Carolina)
INVENTOR(S) Fanxing Li (Raleigh, North Carolina);  Luke Michael Neal (Raleigh, North Carolina);  Yunfei Gao (Raleigh, North Carolina);  Seif Yusuf (Raleigh, North Carolina);  Ryan Dudek (Raleigh, North Carolina)
ABSTRACT Redox catalysts having surface medication, methods of making redox catalysts with surface modification, and uses of the surface modified redox catalysts are provided. In some aspects, the redox catalysts include a core oxygen carrier region such as CaMnO3, BaMnO3−δ, SrMnO3−δ, Mn2SiO4, Mn2MgO4−δ, La0.8Sr0.2O3−δ, La0.8Sr0.2FeO3−δ, Ca9Ti0.1Mn0.9O3−δ, Pr6O11−δ, manganese ore, or a combination thereof; and an outer shell having an average thickness of about 1-100 monolayers surrounding the outer surface of the core region. The outer shell can include, for example a salt selected such as Li2WO4, Na2WO4, K2WO4, SrWO4, Li2MoO4, Na2MoO4, K2MoO4, CsMoO4, Li2CO3, Na2CO3, K2CO3, or a combination thereof.
FILED Thursday, June 14, 2018
APPL NO 16/622627
ART UNIT 1738 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/14 (20130101)
B01J 23/002 (20130101) Original (OR) Class
B01J 23/02 (20130101)
B01J 23/005 (20130101)
B01J 23/30 (20130101)
B01J 23/34 (20130101)
B01J 35/002 (20130101)
B01J 35/0006 (20130101)
B01J 35/10 (20130101)
B01J 37/06 (20130101)
B01J 37/12 (20130101)
B01J 37/16 (20130101)
B01J 37/0081 (20130101)
B01J 37/088 (20130101)
B01J 37/0215 (20130101)

Acyclic or Carbocyclic Compounds
C07C 4/06 (20130101)
C07C 5/48 (20130101)
C07C 11/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814285 McFarland et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Eric W. McFarland (Santa Barbara, California);  Ches Upham (Menlo Park, California);  Jiren Zeng (Goleta, California);  Clarke Palmer (Goleta, California);  Shizhao Su (Santa Barbara, California);  Davide Mannini (Santa Barbara, California);  Dohyung Kang (Goleta, California);  Nazanin Rahimi (Goleta, California);  Horia Metiu (Santa Barbara, California);  Michael Gordon (Goleta, California)
ABSTRACT The reaction rate of hydrocarbon pyrolysis can be increased to produce solid carbon and hydrogen by the use of molten materials which have catalytic functionality to increase the rate of reaction and physical properties that facilitate the formation and contamination-free separation of the solid carbon. Processes, materials, reactor configurations, and conditions are disclosed whereby methane and other hydrocarbons can be decomposed at high reaction rates into hydrogen gas and carbon products without any carbon oxides in a single reaction step. The process also makes use of specific properties of selected materials with unique solubilities and/or wettability of products into (and/or by) the molten phase to facilitate generation of purified products and increased conversion in more general reactions.
FILED Friday, November 16, 2018
APPL NO 16/764226
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 8/0278 (20130101)
B01J 23/825 (20130101)
B01J 23/8437 (20130101)
B01J 27/08 (20130101)
B01J 35/0006 (20130101)
B01J 35/12 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/26 (20130101) Original (OR) Class
C01B 2203/0277 (20130101)
C01B 2203/1011 (20130101)
C01B 2203/1058 (20130101)
C01B 2203/1241 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814299 Fan et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) UNIVERSITY OF WYOMING (Laramie, Wyoming)
ASSIGNEE(S) UNIVERSITY OF WYOMING (Laramie, Wyoming)
INVENTOR(S) Maohong Fan (Ames, Iowa);  Zaixing Huang (Laramie, Wyoming)
ABSTRACT Embodiments of the present disclosure generally relate to the recovery and extraction of rare earth elements. More specifically, embodiments of the disclosure relate to methods for separating rare earth elements from coal, coal by-product(s), and/or coal-derived product(s). In an embodiment, a method of removing rare earth elements from a coal-derived product is provided. The method generally includes introducing supercritical CO2 to the coal ash to form a first mixture, introducing a first acid to the first mixture to form a second mixture, and removing a first composition from the second mixture, the first composition comprising the one or more rare earth elements.
FILED Monday, May 10, 2021
APPL NO 17/316315
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 17/10 (20200101) Original (OR) Class
C01F 17/224 (20200101)

Production and Refining of Metals; Pretreatment of Raw Materials
C22B 3/06 (20130101)
C22B 3/165 (20130101)
C22B 59/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814595 Lopez Pintor et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Dario Lopez Pintor (Livermore, California);  John E. Dec (Livermore, California)
ABSTRACT According to various aspects, an additive for a hydrocarbon-based fuel has a formula (I), in which R1, R2, and R3 are each independently selected from —H, —CH3, or —CH2CH3, and at least one of R1, R2, or R3 is not —H. The additive improves an autoignition reactivity of the hydrocarbon-based fuel. The additive can be present in the fuel composition including the additive and the hydrocarbon-based fuel in an amount of 0.1% by volume to 5% by volume. The hydrocarbon-based fuel can comprise gasoline or diesel.
FILED Tuesday, October 25, 2022
APPL NO 17/973172
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/06 (20130101)
C10L 1/08 (20130101)
C10L 1/231 (20130101) Original (OR) Class
C10L 2200/0259 (20130101)
C10L 2270/023 (20130101)
C10L 2270/026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814616 Lammers et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Peter Lammers (Tempe, Arizona);  Mark Seger (Gilbert, Arizona);  Wonkun Park (Chandler, Arizona);  Nicholas Csakan (Mesa, Arizona)
ABSTRACT The present disclosure relates to methods of culturing algae that overcomes catabolic repression of photosynthesis in mixotrophic growth.
FILED Friday, December 14, 2018
APPL NO 16/767948
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 33/00 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 21/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814700 Verba et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S) United States Department of Energy (Washington, District of Columbia)
INVENTOR(S) Circe Verba (Albany, Oregon);  Mark L. McKoy (Bruceton Mills, West Virginia);  Thomas J. Tarka (Pittsburgh, Pennsylvania);  Scott Montross (Albany, Oregon);  Jonathan Yang (Corvallis, Oregon)
ABSTRACT One or more embodiments relates to a process for extracting Rare Earth Elements (REEs) from REE-bearing underclays, claystones, shales, coal-mining waste, and waste coal. In at least one embodiment the process includes contacting the REE-bearing underclays, claystones, shales, coal-mining waste, and waste coal with an Organic Acid Solution (OAS) comprising at least one organic acid and at least one ionic salt at a predetermined ambient temperature and predetermined pH; and separating the REE from the REE-bearing underclays, claystones, shales, coal-mining waste, and waste coal, forming REE+Yttrium (REY) concentrate.
FILED Thursday, September 29, 2022
APPL NO 17/955731
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Production and Refining of Metals; Pretreatment of Raw Materials
C22B 3/22 (20130101)
C22B 3/165 (20130101) Original (OR) Class
C22B 59/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814965 Dyson et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Thomas Earl Dyson (Niskayuna, New York);  Nicholas William Rathay (Rock City Falls, New York);  Adam John Fredmonski (Simpsonville, South Carolina)
ABSTRACT A turbomachine blade, and a coupon for a turbomachine blade, are disclosed. The blade may include an airfoil body having a pressure side and a suction side connected by a leading edge and a trailing edge, a coolant feed passage defined in the airfoil body, and a coolant reuse passage defined in the airfoil body. The blade may also include a first cooling circuit defined in the airfoil body. The first cooling circuit may include a rearward passage extending toward the trailing edge from and fluidly coupled to the coolant feed passage, and a radially spreading return passage extending away from the trailing edge toward and fluidly coupled to the coolant reuse passage. The cooling circuit may also include a radially extending turn passage coupling the rearward passage and the radially spreading return passage. A first set of obstructions may be positioned in the radially extending turn passage.
FILED Wednesday, November 10, 2021
APPL NO 17/454363
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/147 (20130101)
F01D 5/187 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/304 (20130101)
F05D 2260/202 (20130101)
F05D 2260/232 (20130101)
F05D 2260/608 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815060 Boren et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Blake Craig Boren (Corvallis, Oregon);  Jochem Weber (Golden, Colorado)
ABSTRACT Disclosed herein are flexible wave energy converters that actuate electrical generators with dynamic strain (e.g., flexing, stretching, twisting, distension) to convert wave energy to electrical energy. The flexible wave energy converter utilizes flexible electric generators embedded throughout the wave-energy converter's flexible body.
FILED Tuesday, June 28, 2022
APPL NO 17/851418
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Machines or Engines for Liquids
F03B 13/188 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815376 Cetiner et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Mustafa S. Cetiner (Knoxville, Tennessee);  Trevor K. Howard (Knoxville, Tennessee);  Annalisa Manera (Ann Arbor, Michigan);  Victor Petrov (Ann Arbor, Michigan);  Jiaxin Mao (Ann Arbor, Michigan)
ABSTRACT A system for measuring gas flow generally including a passive acoustic wave generator disposed in a gas flow stream to passively generate an audio signal through vortex shedding, a sound capturing instrument disposed outside the gas stream to produce an electrical signal representative of the acoustic signal, a temperature sensor to obtain temperature measurements indicative of the temperature of the gas flow stream and a control system for determining the gas flow, such as velocity or flow rate, as a function of the acquired acoustic and temperature measurements. The acoustic wave generator includes a corrugated flow channel whose geometric design is so tuned to generate an acoustic emission whose frequency signature varies as a function of the gas flow velocity. The control system may acquires time-domain acoustic data, and process that data to obtain a frequency-domain representation from which gas velocity or gas flow rate can be determined.
FILED Wednesday, June 16, 2021
APPL NO 17/349087
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 1/3218 (20130101)
G01F 1/3287 (20220101) Original (OR) Class
G01F 15/043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815557 Gering
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho)
INVENTOR(S) Kevin L. Gering (Idaho Falls, Idaho)
ABSTRACT An energy storage device (ESD) manager determines charge conditions that result in charge-related aging of an energy storage device (ESD), such as a battery, cell, or the like. The ESD manager may determine charge-related costs for charge operations, which may quantify charge-related aging imposed by subjecting ESD to specified charge conditions. The ESD manager may evaluate and/or modify charge operations to reduce charge-related aging. The ESD manager may be further configured to model charge-related aging behavior over time and/or under variable charge conditions. The ESD manager may configure charge operations to ensure that charge-related performance loss remains below a threshold for a specified usage duration.
FILED Wednesday, September 09, 2020
APPL NO 17/015369
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/374 (20190101)
G01R 31/392 (20190101) Original (OR) Class

Electric Digital Data Processing
G06F 17/18 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/443 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/0071 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815705 Nguyen
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Hoang T Nguyen (Livermore, California)
ABSTRACT Optical thin film designs are provided that achieve significantly improved laser damage thresholds and ultra-low-loss. These advances may be achieved by utilizing materials with electronic band gaps and refractive indices that are higher than those that are conventionally used.
FILED Wednesday, November 27, 2019
APPL NO 16/698555
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/11 (20130101)
G02B 5/1833 (20130101)
G02B 5/1847 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11816053 Chen et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S) Brookhaven Science Associates, LLC (Upton, New York)
ASSIGNEE(S) Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S) Kai Chen (Ridge, New York);  Michael Begel (South Setauket, New York);  Hucheng Chen (Wading River, New York);  Francesco Lanni (Segny, France)
ABSTRACT A reconfigurable data acquisition card including at least one field programmable gate array (FPGA) and a configurable bus switch coupled with the FPGA. The bus switch forms at least first and second ports used by the FPGA, the bus switch being adaptable for insertion into a connection having a number of lanes at least equal to a combined number of lanes in the first and second ports. The data acquisition card further includes multiple optical transmitters and optical receivers. Each optical transmitter and optical receiver is coupled with a corresponding transceiver in the FPGA via at least one optical fiber having multiple communication links. Timing circuitry in the data acquisition card is coupled with clock generation and distribution circuitry in the FPGA and is configured to distribute clock and timing signals to detector front-ends with fixed latency and to synchronize input/output links with a system clock generated by the FPGA.
FILED Monday, September 23, 2019
APPL NO 17/428810
ART UNIT 2181 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 13/4022 (20130101) Original (OR) Class

Pulse Technique
H03K 19/14 (20130101)

Transmission
H04B 10/40 (20130101)

Multiplex Communication
H04J 3/0685 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817250 Takken et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Todd E. Takken (Brewster, New York);  Xin Zhang (Yorktown Heights, New York)
ABSTRACT A broadside coupled coplanar inductor device includes first and second coplanar inductors in which the conductors of the first and second coplanar inductors are broadside coupled. The conductors are located one above the other at a first distance and the return paths are located to the side of the respective first and second conductor signal paths at a second distance. One or both of the dimensions of the first and second first distances is defined so as to maximize a mutual inductance between the conductors. First and second driver circuit apply voltages across each conductor. The input pulse width modulation signals applied to the first and second driver circuits are 180 degrees out of phase.
FILED Tuesday, May 07, 2019
APPL NO 16/405071
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 27/2804 (20130101) Original (OR) Class
H01F 41/041 (20130101)
H01F 2027/2819 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817569 Visco et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) PolyPlus Battery Company (Berkeley, California)
ASSIGNEE(S) PolyPlus Battery Company (Berkeley, California)
INVENTOR(S) Steven J. Visco (Berkeley, California);  Vitaliy Nimon (San Francisco, California);  Yevgeniy S. Nimon (Danville, California);  Bruce D. Katz (Moraga, California);  Richard L. Swisher (Northfield, Minnesota)
ABSTRACT Methods for making solid-state laminate electrode assemblies include methods of forming a solid electrolyte interphase (SEI) by ion implanting nitrogen and/or phosphorous into the glass surface by ion implantation.
FILED Thursday, August 04, 2022
APPL NO 17/817494
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 17/3626 (20130101)
C03C 17/3649 (20130101)
C03C 17/3671 (20130101)
C03C 2218/151 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/24 (20130101)
C23C 14/34 (20130101)
C23C 14/48 (20130101)
C23C 14/0641 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/382 (20130101)
H01M 4/0407 (20130101)
H01M 4/0423 (20130101) Original (OR) Class
H01M 4/628 (20130101)
H01M 4/1395 (20130101)
H01M 10/052 (20130101)
H01M 10/0562 (20130101)
H01M 2300/0068 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817589 Pan et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Ke-Ji Pan (Ellicott City, Maryland);  Mohammed Hussain Abdul Jabbar (College Park, Maryland);  Dong Ding (Idaho Falls, Idaho);  Eric Wachsman (Fulton, Maryland)
ASSIGNEE(S) Redox Power Systems, LLC (College Park, Maryland);  University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Ke-Ji Pan (Ellicott City, Maryland);  Mohammed Hussain Abdul Jabbar (College Park, Maryland);  Dong Ding (Idaho Falls, Idaho);  Eric Wachsman (Fulton, Maryland)
ABSTRACT In various embodiments, a solid oxide fuel cell features a functional layer for reducing interfacial resistance between the cathode and the solid electrolyte.
FILED Tuesday, November 02, 2021
APPL NO 17/516851
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 3/0254 (20130101)
B05D 7/50 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8663 (20130101) Original (OR) Class
H01M 4/9033 (20130101)
H01M 4/9066 (20130101)
H01M 8/126 (20130101)
H01M 8/1213 (20130101)
H01M 8/1246 (20130101)
H01M 8/1253 (20130101)
H01M 2008/1293 (20130101)
H01M 2250/30 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/50 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817606 Evans
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) ESS TECH, INC. (Wilsonville, Oregon)
ASSIGNEE(S) ESS TECH, INC. (Wilsonville, Oregon)
INVENTOR(S) Craig E. Evans (West Linn, Oregon)
ABSTRACT A rebalancing reactor for a redox flow battery system may include a first side through which hydrogen gas is flowed, a second side through which electrolyte from the redox flow battery system is flowed, and a porous layer separating and fluidly coupled to the first side and the second side, wherein, the hydrogen gas and the electrolyte are fluidly contacted at a surface of the porous layer, and a pressure drop across the second side is less than a pressure drop across the porous layer. In this way, rebalancing of electrolyte charges in a redox flow battery system may be performed with increased efficiency and cost effectiveness as compared to conventional rebalancing reactors.
FILED Friday, April 27, 2018
APPL NO 15/965728
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/188 (20130101)
H01M 8/0687 (20130101) Original (OR) Class
H01M 8/2455 (20130101)
H01M 8/04186 (20130101)
H01M 8/04276 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817612 Franzi et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Fermi National Accelerator Laboratory (FNAL)
Federally Funded Research and Development Center (FFRDC)
Operated by Fermi Research Alliance, LLC (FRA) at Batavia, IL
SLAC National Accelerator Laboratory (SLAC)
Federally Funded Research and Development Center (FFRDC)
Operated by Stanford University (LSJU) at Menlo Park, CA
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Matthew A. Franzi (Albuquerque, New Mexico);  Sami G. Tantawi (Stanford, California)
ABSTRACT A non-reciprocal microwave network is provided that includes an in-line ferromagnetic element with adjoining polarizing adapters to achieve directivity via a multi-mode interaction at or near the ferrite to act as new class of 4-port circulator or 2-port isolator, with standard waveguide inputs for assembly in larger networks.
FILED Tuesday, November 30, 2021
APPL NO 17/537846
ART UNIT 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/174 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817761 Alahyari et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S) HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina)
INVENTOR(S) Abbas A. Alahyari (Glastonbury, Connecticut);  Joseph Turney (Amston, Connecticut);  Jagadeesh Kumar Tangudu (South Windsor, Connecticut);  Kimberly Rae Saviers (Glastonbury, Connecticut)
ABSTRACT Aircraft electric motors are described. The aircraft electric motors include a motor unit having a rotor and a stator, wherein the stator includes a plurality of windings and cooling channels arranged to provide cooling to the plurality of windings, a drive unit configured to drive operation of the motor unit, and a cooling system having at least one directional feature forming a portion of at least one cooling channel, the at least one directional feature configured to prevent backflow of a cooling fluid that passes through the at least one cooling channel.
FILED Friday, November 05, 2021
APPL NO 17/519749
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 27/24 (20130101)
B64D 33/08 (20130101)

Dynamo-electric Machines
H02K 5/203 (20210101) Original (OR) Class
H02K 9/20 (20130101)
H02K 11/33 (20160101)
H02K 21/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11812742 Sun et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
Institute of Food Safety and Nutrition (IFSN)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Gang Sun (Davis, California);  Yang Si (Davis, California);  Zheng Zhang (Davis, California)
ABSTRACT This invention provides antibacterial and antiviral compositions and methods. The compositions possess prolonged and powerful antibacterial/antiviral functions under light exposure and even under completely dark conditions, while daylight exposures could recharge the functions repeatedly. In some embodiments, compositions of the invention can be employed in personal protective equipment (PPE) such as face masks, biologically self-cleaning air and water filters, medical devices, and products. The biocidal PPE can prevent transmission of infectious diseases such as Ebola and respiratory viruses. In some embodiments, compositions of the invention can be employed in food protectant materials to provide antimicrobial and antiviral bio-protection during food transportation and storage.
FILED Monday, March 30, 2020
APPL NO 16/834484
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 25/10 (20130101) Original (OR) Class
A01N 25/34 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/14 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 1/103 (20130101)

Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials
D06M 13/1845 (20130101)
D06M 16/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813319 Gladue et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Douglas P. Gladue (Guilford, Connecticut);  Manuel V. Borca (Westbrook, Connecticut)
ABSTRACT Provided herein are details on the construction of a recombinant African Swine Fever Virus (ASFV) live attenuated vaccine for prevention of ASF caused by various strains of ASFV, such as the highly virulent Georgia 2007 isolate (“ASFV-G”). An exemplary vaccine comprises the ASFV-GΔI1771 modified virus, a recombinant ASFV-G modified by deleting a portion of the I177L ORF rendering the I177L gene nonfunctional.
FILED Tuesday, April 06, 2021
APPL NO 17/223252
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/5254 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813320 Rieder et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Department of Agriculture (USDA)
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia);  THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California);  THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia);  THE UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
INVENTOR(S) Aida E. Rieder (Westbrook, Connecticut);  Teresa B. De Los Santos (Miller Place, New York);  Luis L. Rodriguez (Clinton, Connecticut);  Devendra Rai (Old Saybrook, Connecticut);  Fayna C. Diaz-San Segundo (Ronkonkoma, New York);  Paul D. Hoeprich (Pleasanton, California)
ABSTRACT Genetically engineered Foot and Mouth Disease Virus (FMDV) and related engineered proteins and polynucleotides, nanolipoprotein particles, compositions, methods and systems are described. The genetically engineered FMDV is modified by the strategic insertion of a protein tag into select regions of the FMDV genome which encode viral proteins that are exposed on the surface of the FMDV viral capsid. The inserted protein tag is displayed as a decoration or attachment on the viral capsid surface.
FILED Tuesday, February 16, 2021
APPL NO 17/176989
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/135 (20130101) Original (OR) Class
A61K 2039/5254 (20130101)
A61K 2039/55555 (20130101)
A61K 2039/55566 (20130101)
A61K 2039/55572 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/32122 (20130101)
C12N 2770/32134 (20130101)
C12N 2770/32141 (20130101)
C12N 2770/32162 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/70 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814533 Goddard et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Julie M. Goddard (Ithaca, New York);  Zhuangsheng Lin (Amherst, Massachusetts)
ABSTRACT The present invention is directed to a curable polymer comprising: a base acrylic monomer (monomer A); a monomer with bioactive functionality (monomer B); a monomer containing a cross-linker (monomer C). The present invention also relates to a method of making a polymer coating on a solid support. The present invention also relates to a method of preserving a product.
FILED Friday, June 22, 2018
APPL NO 16/626186
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages
B65D 1/0215 (20130101)
B65D 23/02 (20130101)
B65D 25/14 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 2/46 (20130101)
C08F 220/68 (20130101)

Compositions of Macromolecular Compounds
C08L 33/04 (20130101)
C08L 33/14 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 133/04 (20130101)
C09D 133/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814628 Van Oosterwijk et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) US Biologic, Inc. (Memphis, Tennessee);  The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) US Biologic, Inc (Memphis, Tennessee)
INVENTOR(S) Jolieke Gerdy Van Oosterwijk (Memphis, Tennessee);  Luciana Meirelles Richer (Memphis, Tennessee);  Douglas Steven Zatechka (Cordova, Tennessee);  Woohyun Kim (Ellicott city, Maryland);  Hyun Soon Lillehoj (West Friendship, Maryland);  Cyril Gray (Bethesda, Maryland);  Christopher Anthony Przybyszewski (Southhaven, Mississippi)
ABSTRACT The inventive subject matter includes an antimicrobial peptide vectored composition made of a bacterial protein expression vehicle expressing one or more recombinant antimicrobial peptide effector molecules. More specifically these novel recombinant antimicrobial peptide effector molecules exhibit preferential anti-microbial activity. The utility of the current inventive subject matter has demonstrated a reduced viability of Eimeira acervulina sporozoites in vitro using a sporozoite killing assay. More specifically, the antimicrobial peptide vectored composition is a bacterial protein expression vehicle expressing one or more recombinant antimicrobial peptide effector molecules, wherein the one or more recombinant antimicrobial peptide effector molecules are engineered from a NK-lysin gene and the one or more recombinant antimicrobial peptide effector molecules are engineered to express functionally active NK-2.
FILED Monday, June 14, 2021
APPL NO 18/008512
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 35/742 (20130101)

Peptides
C07K 14/465 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/75 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11813395 Kelley
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Andrew Kelley (Chelmsford, Massachusetts)
ABSTRACT An external catheter system can comprise an external catheter comprising an engagement portion that is configured to receive and sealingly engage at least a portion of a penis of a user and an outlet. The system can further comprise a negative pressure source. A conduit can couple the negative pressure source to the external catheter. At least one of the external catheter and the conduit can comprise a portion that, upon application of a negative pressure by the negative pressure source, is configured to collapse to provide a pressure drop between the negative pressure source and the engagement portion of the external catheter.
FILED Tuesday, November 17, 2020
APPL NO 16/950417
ART UNIT 3781 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/90 (20210501) Original (OR) Class
A61M 2202/0496 (20130101)
A61M 2205/0216 (20130101)
A61M 2210/167 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813485 Xu et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Zhen Xu (Ann Arbor, Michigan);  Clifford Suhyun Cho (Ann Arbor, Michigan)
ABSTRACT Systems and methods for histotripsy and immunotherapy are provided. In some embodiments, histotripsy can be applied to a target tissue volume to lyse and solubilize the target tissue volume to release tumor antigens. In some embodiments, an immune response of the treatment can be evaluated. In other embodiments, an immune therapy can be applied after applying the histotripsy. In one embodiment, the lysed and solubilized cells can be extracted from the tissue. The extracted cells can be used to create immune therapies, including vaccines.
FILED Thursday, January 28, 2021
APPL NO 17/161498
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/0045 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0011 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814687 Kim et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts);  Baylor College of Medicine (Houston, Texas);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Northwestern University (Evanston, Illinois);  The Johns Hopkins University (Baltimore, Maryland);  United States Government as represented by the U.S. Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts);  Baylor College of Medicine (Houston, Texas);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Northwestern University (Evanston, Illinois);  The Johns Hopkins University (Baltimore, Maryland);  United States Government as represented by the U.S. Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Jaegil Kim (Cambridge, Massachusetts);  Gad Getz (Boston, Massachusetts);  Seth Paul Lerner (Houston, Texas);  David Kwiatkowski (Boston, Massachusetts);  Joshua Meeks (Evanston, Illinois);  Joaquim Bellmunt (Cambridge, Massachusetts);  David McConkey (Baltimore, Maryland)
ABSTRACT The present invention features methods for characterizing mutational profiles in patients with bladder cancer.
FILED Friday, August 07, 2020
APPL NO 16/988317
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817204 Madabhushi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio);  The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia)
INVENTOR(S) Anant Madabhushi (Shaker Heights, Ohio);  Nathaniel Braman (Bethel Park, Pennsylvania);  Tristan Maidment (Cleveland, Ohio);  Yijiang Chen (Cleveland, Ohio)
ABSTRACT Embodiments discussed herein facilitate determination of whether lesions are benign or malignant. One example embodiment is a method, comprising: accessing medical imaging scan(s) that are each associated with distinct angle(s) and each comprise a segmented region of interest (ROI) of that medical imaging scan comprising a lesion associated with a first region and a second region; providing the first region(s) of the medical imaging scan(s) to trained first deep learning (DL) model(s) of an ensemble and the second region(s) of the medical imaging scan(s) to trained second DL model(s) of the ensemble; and receiving, from the ensemble of DL models, an indication of whether the lesion is a benign architectural distortion (AD) or a malignant AD.
FILED Wednesday, December 09, 2020
APPL NO 17/116366
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/025 (20130101)
A61B 6/469 (20130101)
A61B 6/502 (20130101)
A61B 6/5217 (20130101)

Electric Digital Data Processing
G06F 18/214 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101)
G06T 2207/10112 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30068 (20130101)
G06T 2207/30096 (20130101)

Image or Video Recognition or Understanding
G06V 10/25 (20220101)
G06V 10/82 (20220101)
G06V 10/764 (20220101)
G06V 2201/03 (20220101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101) Original (OR) Class
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11814195 Choi
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Michael Choi (Greenbelt, Maryland)
ABSTRACT The present invention relates to an innovative thermal design concept of tailoring the absorptance and emittance of a coating—namely silicon oxide (SiOx) coated aluminized Kapton—as a radiator coating for small, nano-satellite (i.e., CubeSat) thermal management. The present invention improves on the thermal design of existing satellites, by: a) thermally coupling all components to the baseplate to eliminate the need for heater power for the battery; b) using all six sides of the CubeSat as radiators by changing the wall material from fiberglass to aluminum; c) using a different ratio of absorptance to emittance for each side by tailoring the SiOx thickness; d) having a high emittance for the wall interior and components; and e) eliminating the need for MLIs. The elimination of the MLIs reduces the volume and increases the clearance to minimize the risk for solar array deployment and cost of the thermal control subsystem.
FILED Monday, August 26, 2019
APPL NO 16/550977
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/10 (20130101)
B64G 1/226 (20130101) Original (OR) Class
B64G 1/409 (20130101)
B64G 1/425 (20130101)
B64G 1/443 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 33/12 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/14 (20130101)
C04B 35/62222 (20130101)
C04B 2235/3293 (20130101)
C04B 2235/3418 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815074 Benavides et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Gabriel F. Benavides (Cleveland, Ohio);  Luis R. Pinero (Cleveland, Ohio);  Corey R. Rhodes (Cleveland, Ohio);  Arthur Birchenough (Cleveland, Ohio)
ABSTRACT Scalable power processing units (PPUs) for Hall-effect thrusters (HETs) and terrestrial systems are disclosed. A technique for current estimation may be employed on each output of parallel isolated discharge supply modules (DSMs) to force proper current/load sharing between the DSMs. A flyback power supply may be used that performs the dual functions of a cathode keeper plasma ignitor and sustainer. The flyback power supply may be tuned for a high no-load direct current (DC) output voltage to achieve cathode keeper ignition rather than requiring a separate ignitor supply, which reduces circuit complexity. To address requirements for higher voltage DC ignition than are achievable with a flyback power supply alone, a supplemental DC ignitor may be placed in parallel with the flyback power supply of some embodiments. Such simplified PPU architectures may provide a high efficiency, low part count, scalable architecture suitable for more compact and lower cost system designs.
FILED Friday, June 26, 2020
APPL NO 16/912946
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/405 (20130101)

Producing a Reactive Propulsive Thrust, Not Otherwise Provided for
F03H 1/0012 (20130101)
F03H 1/0018 (20130101)
F03H 1/0075 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815268 Dai et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) Raytheon Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RTX Corporation (Farmington, Connecticut)
INVENTOR(S) Zhongtao Dai (West Hartford, Connecticut);  Lance L. Smith (West Hartford, Connecticut);  Jeffrey M. Cohen (Hebron, Connecticut)
ABSTRACT A main mixer including a swirler along an axis, the swirler including an outer swirler with a multiple of outer vanes, and a center swirler with a multiple of center vanes and a swirler hub along the axis, the swirler hub including a fuel manifold and an inner swirler with a multiple of inner vanes that support a centerbody, the multiple of inner vanes interconnect the fuel manifold and the centerbody.
FILED Thursday, July 08, 2021
APPL NO 17/370154
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/14 (20130101)
F23R 3/286 (20130101) Original (OR) Class
F23R 2900/03041 (20130101)
F23R 2900/03042 (20130101)
F23R 2900/03044 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 50/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11816996 Smith-Velazquez et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Neil A Armstrong Flight Research Center (AFRC)
APPLICANT(S) Rockwell Collins, Inc. (Cedar Rapids, Iowa)
ASSIGNEE(S) Rockwell Collins, Inc. (Cedar Rapids, Iowa)
INVENTOR(S) Laura M. Smith-Velazquez (Owings Mills, Maryland);  Erik Theunissen (Leiderdorp, Netherlands)
ABSTRACT A system for predicting pressure waves in a sonic boom footprint calculates alternative footprints and pressure waves along a flight path based on speed and altitude modifiers. The available, adjustable parameters are bounded within a flight envelope and along an approved flight corridor. The system receives and incorporates data from external sources, such as weather data, that impacts sonic boom pressure wave predictions and aircraft performance characteristics.
FILED Friday, December 13, 2019
APPL NO 16/714299
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 23/005 (20130101)

Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves
G01H 17/00 (20130101)

Traffic Control Systems
G08G 5/006 (20130101)
G08G 5/0021 (20130101) Original (OR) Class
G08G 5/0039 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11812966 Dreilinger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) NeuraMedica Inc. (Oregon City, Oregon)
ASSIGNEE(S) NeuraMedica Inc. (Oregon City, Oregon)
INVENTOR(S) Rachel Dreilinger (Beavercreek, Oregon);  Neil Roundy (Eugene, Oregon);  Mariah Knight (Cornelius, Oregon);  Sandra Baker (Tigard, Oregon)
ABSTRACT A medical device forming method, an applier for manipulating clips, and a cartridge for holding clips are disclosed herein.
FILED Friday, April 24, 2020
APPL NO 16/858546
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/083 (20130101) Original (OR) Class
A61B 17/1222 (20130101)
A61B 2017/0488 (20130101)
A61B 2017/00584 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813184 Sicotte et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ZENFLOW, INC. (San Francisco, California)
ASSIGNEE(S) ZENFLOW, INC. (San Francisco, California)
INVENTOR(S) Marcel Song Sicotte (San Francisco, California);  Shreya Mehta (San Francisco, California);  Austin Michael Bly (San Clemente, California);  Ronald J. Jabba (Redwood City, California)
ABSTRACT Benign prosthetic hyperplasia (BPH) is a non-cancerous enlargement of the prostate gland. Treatment options for BPH include medication, surgery (e.g., removal of enlarged prostate tissue), and minimally invasive procedures (e.g., needle ablation, electrovaporization, thermotherapy, and stent insertion). Minimally invasive procedure is typically the preferred choice if medication is ineffective. Accordingly, disclosed herein are system and method for treating BPH using improved implant and delivery device. Certain embodiments of the delivery device can include: a camming barrel having a first groove at the distal end of the camming barrel; a sheath, located within a lumen of the camming barrel, for storing the implantable device; and a first cam follower coupled to the sheath.
FILED Wednesday, February 17, 2021
APPL NO 17/177772
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/3468 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/885 (20130101)
A61F 2/966 (20130101) Original (OR) Class
A61F 2/9517 (20200501)
A61F 2002/048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11813289 Milgrom et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ADVANTAGE SILVER DENTAL ARREST, LLC (Salem, Oregon)
ASSIGNEE(S) ADVANTAGE SILVER DENTAL ARREST, LLC (Salem, Oregon)
INVENTOR(S) Peter M. Milgrom (Seattle, Washington);  Jong Seto (San Francisco, California)
ABSTRACT The invention provides compositions and methods that comprise encapsulated silver diamine fluoride or other antimicrobial materials for use in treatment of dental caries, for example.
FILED Friday, April 05, 2019
APPL NO 17/252963
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 9/501 (20130101)
A61K 9/5073 (20130101)
A61K 9/5089 (20130101)
A61K 33/38 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 47/02 (20130101)
A61K 47/16 (20130101)
A61K 47/32 (20130101)
A61K 47/34 (20130101)
A61K 47/46 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817524 Welser et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Magnolia Optical Technologies, Inc. (Woburn, Massachusetts)
ASSIGNEE(S) Magnolia Optical Technologies, Inc. (Woburn, Massachusetts)
INVENTOR(S) Roger E. Welser (Providence, Rhode Island);  Ashok K. Sood (Brookline, Massachusetts)
ABSTRACT Refractive optical element designs are provided for high geometric optical efficiency over a wide range of incident angles. To minimize Fresnel reflection losses, the refractive optical element designs employ multiple encapsulant materials, differing in refractive index. Concentrator photovoltaic subassemblies are formed by embedding a high efficiency photovoltaic device within the refractive optical element, along with appropriate electrical contacts and heat sinks. Increased solar electric power output is obtained by employing a single-junction III-V material structure with light-trapping structures.
FILED Monday, November 15, 2021
APPL NO 17/526623
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/115 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/048 (20130101)
H01L 31/056 (20141201)
H01L 31/065 (20130101)
H01L 31/184 (20130101)
H01L 31/186 (20130101)
H01L 31/0203 (20130101)
H01L 31/0232 (20130101)
H01L 31/0445 (20141201)
H01L 31/0481 (20130101)
H01L 31/0543 (20141201)
H01L 31/0547 (20141201)
H01L 31/0725 (20130101)
H01L 31/0735 (20130101)
H01L 31/1844 (20130101)
H01L 31/1884 (20130101) Original (OR) Class
H01L 31/02165 (20130101)
H01L 31/02168 (20130101)
H01L 31/03046 (20130101)
H01L 31/022425 (20130101)
H01L 31/022475 (20130101)
H01L 31/035236 (20130101)
H01L 31/035263 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
Y02E 10/52 (20130101)
Y02E 10/544 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11814414 Krishna et al.
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S) REALTA HOLDINGS, LLC (Norfolk, Virginia)
ASSIGNEE(S) REALTA HOLDINGS, LLC (Norfolk, Virginia)
INVENTOR(S) Neel K. Krishna (Norfolk, Virginia);  Kenji Cunnion (Norfolk, Virginia)
ABSTRACT The present invention provides synthetic peptide compounds and uses thereof for therapy and diagnostics of complement-mediated diseases, such as inflammatory diseases, autoimmune diseases, and microbial and bacterial infections; and non-complement-mediated diseases, such cystic fibrosis and various acute diseases. The invention is directed to modifications of a synthetic peptide of 15 amino acids from the Polar Assortant (PA) peptide, which is a scrambled peptide derived from human Astrovirus protein. In some embodiments, the invention is directed to peptide compounds that are peptide mimetics, peptide analogs and/or synthetic derivatives of PA (e.g., sarcosine derivatives) having, for example, internal peptide substitutions, and modifications, including PEGylation at the N-terminus and C-terminus. The invention further provides methods of selecting at least one synthetic peptide for treating various conditions.
FILED Monday, February 08, 2021
APPL NO 17/169758
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/162 (20130101)
A61K 47/60 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/00 (20180101)
A61P 25/00 (20180101)
A61P 37/06 (20180101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2770/12022 (20130101)
C12N 2770/12033 (20130101)
C12N 2770/12071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815528 Grinolds et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Michael S. Grinolds (Cambridge, Massachusetts);  Sungkun Hong (Cambridge, Massachusetts);  Patrick Maletinsky (Cambridge, Massachusetts);  Amir Yacoby (Cambridge, Massachusetts)
ABSTRACT A sensing probe may be formed of a diamond material comprising one or more spin defects that are configured to emit fluorescent light and are located no more than 50 nm from a sensing surface of the sensing probe. The sensing probe may include an optical outcoupling structure formed by the diamond material and configured to optically guide the fluorescent light toward an output end of the optical outcoupling structure. An optical detector may detect the fluorescent light that is emitted from the spin defects and that exits through the output end of the optical outcoupling structure after being optically guided therethrough. A mounting system may hold the sensing probe and control a distance between the sensing surface of the sensing probe and a surface of a sample while permitting relative motion between the sensing surface and the sample surface.
FILED Friday, February 18, 2022
APPL NO 17/675156
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/645 (20130101)
G01N 24/10 (20130101)
G01N 2201/10 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 30/025 (20130101)
G01Q 60/08 (20130101)
G01Q 60/38 (20130101)
G01Q 60/54 (20130101)
G01Q 70/14 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/022 (20130101)
G01R 33/032 (20130101)
G01R 33/60 (20130101)
G01R 33/323 (20130101)
G01R 33/1284 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11817173 Madhavan et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF COMMERCE (Washington, District of Columbia)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland);  GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Advait Madhavan (Bethesda, Maryland);  Matthew William Daniels (Silver Spring, Maryland);  Mark David Stiles (Silver Spring, Maryland)
ABSTRACT Systems and methods are provided herein that implement and utilize temporal state machines and other temporal computational/memory circuits. For example, a temporal state machine is provided that comprises a temporal computational unit comprising at least one circuit to perform a time-domain operation, and a temporal memory unit. Both the temporal computational unit and temporal memory unit can operate using solely, or partially, time-encoded wavefronts. The computation unit accesses time-encoded wavefronts from the memory and can output and write time-encoded wavefronts back to the memory.
FILED Friday, October 01, 2021
APPL NO 17/492526
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Electric Digital Data Processing
G06F 17/16 (20130101)

Static Stores
G11C 5/06 (20130101)
G11C 7/12 (20130101)
G11C 7/222 (20130101) Original (OR) Class
G11C 7/1012 (20130101)
G11C 7/1069 (20130101)
G11C 7/1096 (20130101)

Pulse Technique
H03K 19/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Central Intelligence Agency (CIA) 

US 11814194 Beck et al.
FUNDED BY
Central Intelligence Agency (CIA)
APPLICANT(S) Rocket Lab USA, Inc. (Huntington Beach, California)
ASSIGNEE(S) Rocket Lab USA, Inc. (Long Beach, California)
INVENTOR(S) Peter Beck (Auckland, New Zealand);  Peter Barlow (Huntington Beach, California);  David Yoon (La Crescenta, California);  Ben Malcolm (Auckland, New Zealand)
ABSTRACT A satellite dispenser is disclosed. In various embodiments, a satellite dispenser as disclosed herein includes a dispenser body defining an interior cavity configured to receive a payload; and a composite guide rail comprising a groove configured to receive at least a portion of a payload, the composite guide rail having an orientation that substantially aligns a longitudinal axis of the groove with an ejection axis of the dispenser.
FILED Friday, September 03, 2021
APPL NO 17/466723
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cutting; Details Common to Machines for Perforating, Punching, Cutting-out, Stamping-out or Severing
B26D 5/12 (20130101)

Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects
B60P 7/16 (20130101)
B60P 7/135 (20130101)

Cosmonautics; Vehicles or Equipment Therefor
B64G 1/007 (20130101)
B64G 1/22 (20130101) Original (OR) Class
B64G 1/222 (20130101)
B64G 1/645 (20130101)

Hinges or Suspension Devices for Doors, Windows or Wings
E05D 3/08 (20130101)
E05D 7/00 (20130101)

Devices for Moving Wings into Open or Closed Position; Checks for Wings; Wing Fittings Not Otherwise Provided For, Concerned With the Functioning of the Wing
E05F 1/105 (20130101)
E05F 3/20 (20130101)

Indexing Scheme Relating to Hinges or Other Suspension Devices for Doors, Windows or Wings and Devices for Moving Wings into Open or Closed Position, Checks for Wings and Wing Fittings Not Otherwise Provided For, Concerned With the Functioning of the Wing
E05Y 2201/216 (20130101)
E05Y 2201/426 (20130101)
E05Y 2900/50 (20130101)
E05Y 2900/531 (20130101)

Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings
F16C 29/005 (20130101)
F16C 33/24 (20130101)
F16C 2208/82 (20130101)
F16C 2223/32 (20130101)
F16C 2326/47 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 3/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11815419 Nansteel et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Mark Nansteel (Egg Harbor Township, New Jersey);  Xianzhi Yang (Cherry Hill, New Jersey);  Roger Veldman (Dorr, Michigan);  Chih-Tsai Chen (Moorestown, New Jersey);  Matthew Ghent (Bel Air, Maryland)
ABSTRACT Examples are directed towards apparatuses, systems, and methods. For example, an apparatus includes a weight including a first side and a second side. The first side of the weight forms a receiving hole in the first side. A pin includes a first end and a second end. The second end of the pin is inserted into the receiving hole of the weight. The pin includes a reduced portion. A pin detonator is coupled to the reduced portion of the pin to sever the pin when detonated.
FILED Wednesday, October 05, 2022
APPL NO 17/960190
ART UNIT 2853 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 5/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 11813054 Dawson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Geospatial Intelligence Agency (NGA)
National Science Foundation (NSF)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Geraldine Dawson (Durham, North Carolina);  Guillermo Sapiro (Durham, North Carolina);  Jordan Hashemi (Durham, North Carolina)
ABSTRACT The subject matter described herein includes methods, systems, and computer readable media for conducting an automatic assessment of postural control of a subject. According to one aspect, a method occurs at a computing platform including a processor and memory. The method includes displaying a stimulus to which a subject responds, capturing facial image data of the subject, analyzing the facial image data to determine a frequency of head displacement information associated with the subject, using the head displacement information to derive postural control assessment data, and determining that the postural control assessment data is indicative of a neurodevelopmental or neuropsychiatric disorder associated with the subject.
FILED Friday, November 08, 2019
APPL NO 16/678828
ART UNIT 2619 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/1116 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 3/012 (20130101)
G06F 3/017 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/70 (20170101)
G06T 2207/30201 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 11816537 Monroe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) UNIVERSITY OF MARYLAND (College Park, Maryland);  DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S) University of Maryland (College Park, Maryland);  Duke University (Durham, North Carolina)
INVENTOR(S) Christopher Monroe (Ellicott City, Maryland);  Jungsang Kim (Chapel Hill, North Carolina)
ABSTRACT A modular quantum computer architecture is developed with a hierarchy of interactions that can scale to very large numbers of qubits. Local entangling quantum gates between qubit memories within a single modular register are accomplished using natural interactions between the qubits, and entanglement between separate modular registers is completed via a probabilistic photonic interface between qubits in different registers, even over large distances. This architecture is suitable for the implementation of complex quantum circuits utilizing the flexible connectivity provided by a reconfigurable photonic interconnect network. The subject architecture is made fault-tolerant which is a prerequisite for scalability. An optimal quantum control of multimode couplings between qubits is accomplished via individual addressing the qubits with segmented optical pulses to suppress crosstalk in each register, thus enabling high-fidelity gates that can be scaled to larger qubit registers for quantum computation and simulation.
FILED Friday, July 23, 2021
APPL NO 17/384574
ART UNIT 2896 — Computer Architecture and I/O
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/113 (20130101)

Electric Digital Data Processing
G06F 15/76 (20130101)
G06F 2015/768 (20130101)

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11813672 Holcomb et al.
FUNDED BY
APPLICANT(S) GRID LOGIC INCORPORATED (Lapeer, Michigan)
ASSIGNEE(S) GRID LOGIC INCORPORATED (Lapeer, Michigan)
INVENTOR(S) Matthew J. Holcomb (Metamora, Michigan);  Ira James Holcomb, Jr. (Shelby Township, Michigan)
ABSTRACT The invention relates to a manufacturing system including a holder suitable to hold first particles of a first powder in proximity to one another, and a connection scheme which, when employed, connects the first particles to one another to form a part.
FILED Friday, May 07, 2021
APPL NO 17/315093
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/12 (20210101)
B22F 12/30 (20210101)
B22F 12/52 (20210101)
B22F 12/53 (20210101) Original (OR) Class
B22F 12/222 (20210101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 40/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814966 Chuong et al.
FUNDED BY
APPLICANT(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) RTX CORPORATION (Farmington, Connecticut)
INVENTOR(S) Conway Chuong (Manchester, Connecticut);  Caroline A. Karanian (West Hartford, Connecticut);  Joey Wong (Enfield, Connecticut)
ABSTRACT A retention ring for a gas turbine engine according to an example of the present disclosure includes, among other things, a main body extending in a circumferential direction about an axis to establish a continuous hoop having a first diameter and a second diameter. The main body includes first and second circumferential faces along opposite sides of the main body. The first circumferential face is dimensioned to abut a gas turbine engine component. The main body includes at least one removal feature dimensioned to sever in response to engagement with a cutting tool. A method of assembly is also disclosed.
FILED Tuesday, March 22, 2022
APPL NO 17/700682
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 11/003 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/60 (20130101)
F05D 2240/55 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11814977 Kessler et al.
FUNDED BY
APPLICANT(S) RTX Corporation (Farmington, Connecticut)
ASSIGNEE(S) RTX CORPORATION (Farmington, Connecticut)
INVENTOR(S) Mason Adam Kessler (Rocky Hill, Connecticut);  Joon Won Ha (Glastonbury, Connecticut);  Subhadeep Gan (Middletown, Connecticut);  Michael Carl Weber (Niantic, Connecticut)
ABSTRACT A flange arrangement of a gas turbine engine includes a first flange of a first component, and a second flange of a second component axially offset from the first flange along an engine central longitudinal axis. The first flange is secured to the second flange. One or more flange flowpaths are defined between the first flange and the second flange to convey a flange airflow from an interior of the second component thereby thermally conditioning the flange arrangement. The flange airflow is driven through the one or more flange flowpaths by a pressure differential.
FILED Monday, August 29, 2022
APPL NO 17/822990
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 25/10 (20130101)
F01D 25/243 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/14 (20130101)
F05D 2260/31 (20130101)
F05D 2260/232 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815029 Amari
FUNDED BY
APPLICANT(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) Raytheon Technologies Corporation (Farmington, Connecticut)
INVENTOR(S) Martin Richard Amari (Glastonbury, Connecticut)
ABSTRACT A system for bleeding air from a core flow path of a gas turbine engine is disclosed. In various embodiments, the system includes a bleed valve having a bleed valve inlet configured to receive a bleed air from a first access point to the core flow path and a bleed valve outlet; and an air motor having a first air motor inlet configured to receive the bleed air from the bleed valve outlet and a first air motor outlet configured to exhaust the bleed air, the air motor configured to pump the bleed air from the core flow path of the gas turbine engine.
FILED Tuesday, August 23, 2022
APPL NO 17/893640
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 6/08 (20130101)
F02C 7/27 (20130101)
F02C 9/18 (20130101) Original (OR) Class

Jet-propulsion Plants
F02K 3/075 (20130101)

Non-positive-displacement Pumps
F04D 27/0207 (20130101)
F04D 27/0215 (20130101)
F04D 27/0223 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2260/85 (20130101)
F05D 2270/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11815718 Puckett et al.
FUNDED BY
APPLICANT(S) Honeywell International Inc. (Charlotte, North Carolina)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Matthew Wade Puckett (Phoenix, Arizona);  Chad Fertig (Bloomington, Minnesota);  Steven Tin (Edina, Minnesota)
ABSTRACT Techniques relating to an improved optical waveguide are described. The optical waveguide includes an upper and lower waveguide that each comprise a first and second layer, in which photons are transferred from the lower waveguide to the upper waveguide. A structured subwavelength coupling region is included, for example, in the first upper waveguide layer. The fill factor of the subwavelength grating coupling region is increased in the direction of light propagation to increase the index of refraction of the structured subwavelength coupling region and therefore improve photon transfer from the lower waveguide. Additionally, the width of the optical waveguide (at least along the structured subwavelength coupling region) remains constant as the fill factor increases.
FILED Friday, November 19, 2021
APPL NO 17/531441
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/14 (20130101)
G02B 6/34 (20130101)
G02B 6/124 (20130101) Original (OR) Class
G02B 6/12002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11818191 Henshaw et al.
FUNDED BY
APPLICANT(S) Two Six Labs, LLC (Arlington, Virginia)
ASSIGNEE(S) Two Six Labs, LLC (Arlington, Virginia)
INVENTOR(S) Seth Henshaw (Arlington, Virginia);  Matthew Blackston (Knoxville, Tennessee)
ABSTRACT An approach for gathering, encoding and transmitting histogram data mitigates the need for transmission resources by compressing the gathered data in a lossless, stateless manner for transmission. A generally sparse data set benefits from an encoding mechanism based on a bit plane arrangement of the raw data. The approach organizes bit planes in a sequential manner, and then encodes values based on intervals of non-zero bit positions. By traversing a sequential string based on the bit plane, each “run” of zeroes tends to produce relatively small values, easing encoding burdens, but also accommodated larger values when necessary. A selective encoding technique invokes different encoding processes based on the magnitude of the interval, to allow use of an encoding that stores each respective value in the fewest bits. Different encoding techniques are applied based on ranges of the interval magnitude, or zero run.
FILED Thursday, November 11, 2021
APPL NO 17/524263
ART UNIT 2441 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 65/70 (20220501) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 14, 2023.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20231114.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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