FedInvent™ Patents

Patent Details for Tuesday, December 05, 2023 

This page was updated on Thursday, December 07, 2023 at 09:55 AM GMT

Department of Health and Human Services (HHS) 

US 11832601 Metcalf et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Eye Institute (NEI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Child Health and Human Development (NICHD)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) VANDERBILT UNIVERSITY (Nashville, Tennessee);  YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee);  YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Jason Metcalf (Dexter, Michigan);  Seth R. Bordenstein (Nashville, Tennessee);  Daniel Lepage (Centertown, Missouri);  Sarah Bordenstein (Nashville, Tennessee);  Mark Hochstrasser (Hamden, Connecticut);  John F. Beckmann (New Haven, Connecticut);  Judith Ronau (Hamden, Connecticut)
ABSTRACT The disclosure relates to genetically modified bacteria, genetically modified arthropods, and methods for controlling and/or reducing arthropod populations.
FILED Friday, June 09, 2017
APPL NO 16/307982
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0337 (20130101) Original (OR) Class
A01K 67/0339 (20130101)
A01K 2217/052 (20130101)
A01K 2217/206 (20130101)
A01K 2227/706 (20130101)
A01K 2267/02 (20130101)

Peptides
C07K 14/195 (20130101)
C07K 2319/21 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/205 (20210501)
C12N 9/22 (20130101)
C12N 9/6472 (20130101)
C12N 15/87 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/01 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11832915 Melodia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Research Foundation for The State University of New York (Amherst, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Amherst, New York)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Zhangyu Guan (Boston, Massachusetts);  Giuseppe Enrico Santagati (Cambridge, Massachusetts)
ABSTRACT Methods for ultrasonic communications through biological tissue using ultrasonic pulses are disclosed. For example, methods for calculating a forward data generation rate and a forward transmission probability profile for ultrasonic communications through biological material are disclosed. The method may comprise measuring sets interference values corresponding to instants on a communication channel. First and second order moments may be calculated for each instant based on the measured interference values. An outage probability may be calculated for each set and the forward data generation rate and forward transmission probability profile may be calculated based on the outage probability value and other parameters and a threshold transmission rate, a transmission delay threshold, and a residual transmission error rate.
FILED Tuesday, December 17, 2019
APPL NO 16/717591
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0015 (20130101)
A61B 5/0024 (20130101)
A61B 5/0028 (20130101) Original (OR) Class
A61B 5/0031 (20130101)
A61B 5/0205 (20130101)
A61B 5/7203 (20130101)
A61B 5/7225 (20130101)
A61B 5/14532 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/14244 (20130101)

Transmission
H04B 11/00 (20130101)
H04B 17/15 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833124 Su et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  CLEVELAND STATE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Bin Su (Cleveland, Ohio);  Monica M. Montano (Cleveland, Ohio)
ABSTRACT A method of inducing HEXIM1 expression in cells of a subject includes administering to the cells a compound having the formula,
and pharmaceutically acceptable salts thereof.
FILED Tuesday, March 30, 2021
APPL NO 17/217084
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/16 (20130101)
A61K 31/16 (20130101)
A61K 31/18 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833137 Hu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Wistar Institute (Philadelphia, Pennsylvania);  University of South Florida (Tampa, Florida)
ASSIGNEE(S) The Wistar Institute (Philadelphia, Pennsylvania);  University of South Florida (Tampa, Florida)
INVENTOR(S) Chih-Chi Andrew Hu (Philadelphia, Pennsylvania);  Juan R. Del Valle (Tampa, Florida)
ABSTRACT The present invention includes substituted chromenones that are useful to inhibit the IRE1/XBP-1 pathway. In certain embodiments, the compounds of the invention inhibit IRE1's RNase activity. In other embodiments, the compounds of the invention are useful to treat or prevent a cancer that involve activation of the ER stress response. The invention also relates, in certain aspects, to the discovery that secretory IgM (sIgM) can orchestrate an immunosuppressive microenvironment by recruiting myeloid-derived suppressor cells (MDSCs) into different tumor models, such as but not limited to solid tumors (such as but not limited to lung cancer) and tumors that have high levels of secreted IgM. In certain embodiments, sIgM produced by B cells or CLL cells can contribute to the accumulation of MDSCs in a tumor. In other embodiments, inhibition of the IRE1/XBP-1 pathway can ablate, minimize, or reduce MDSC levels in a tumor.
FILED Monday, April 01, 2019
APPL NO 17/041529
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/436 (20130101) Original (OR) Class
A61K 31/519 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 491/052 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833159 McCall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) ReveraGen BioPharma, Inc. (Rockville, Maryland)
ASSIGNEE(S) ReveraGen BioPharma, Inc. (Rockville, Maryland)
INVENTOR(S) John M. McCall (Boca Grande, Florida);  Eric Hoffman (Rockville, Maryland);  Kanneboyina Nagaraju (Highland, Maryland)
ABSTRACT The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy.
FILED Wednesday, October 28, 2020
APPL NO 17/082521
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/57 (20130101)
A61K 31/573 (20130101) Original (OR) Class
A61K 31/575 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/04 (20180101)
A61P 1/16 (20180101)
A61P 3/00 (20180101)

Steroids
C07J 5/0038 (20130101)
C07J 5/0053 (20130101)
C07J 5/0076 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833172 Liechty et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado);  UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida);  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado);  UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida)
INVENTOR(S) Kenneth Liechty (Aurora, Colorado);  Sudipta Seal (Orlando, Florida);  Robert Gorman (Philadelphia, Pennsylvania)
ABSTRACT The present disclosure relates to wound treatment and therapy and the promotion of tissue regeneration following injury. In particular, it relates to a microRNA-146a and nanoceria conjugate for improving wound healing and, in some embodiments, preventing adverse ventricular remodeling following myocardial infarction.
FILED Wednesday, November 23, 2016
APPL NO 15/779123
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 9/14 (20130101)
A61K 9/0019 (20130101)
A61K 31/728 (20130101)
A61K 33/24 (20130101) Original (OR) Class
A61K 47/55 (20170801)
A61K 47/549 (20170801)
A61K 47/6923 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 29/00 (20180101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 17/235 (20200101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/141 (20130101)
C12N 2310/351 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833196 Moon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) James J. Moon (Ann Arbor, Michigan);  Rui Kuai (Ann Arbor, Michigan);  Anna A. Schwendeman (Ann Arbor, Michigan);  Jutaek Nam (Ann Arbor, Michigan)
ABSTRACT The present invention relates to nanoparticles complexed with biomacromolecule agents configured for treating, preventing or ameliorating various types of disorders, and methods of synthesizing the same. In particular, the present invention is directed to compositions comprising nanoparticles (e.g., synthetic high density lipoprotein (sHDL)) carrying biomacromolecule agents (e.g., nucleic acid, peptides, glycolipids, etc.), methods for synthesizing such nanoparticles, as well as systems and methods utilizing such nanoparticles (e.g., in diagnostic and/or therapeutic settings).
FILED Thursday, October 14, 2021
APPL NO 17/501576
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 31/712 (20130101)
A61K 31/713 (20130101)
A61K 31/7088 (20130101)
A61K 39/0011 (20130101) Original (OR) Class
A61K 39/00111 (20180801)
A61K 39/001106 (20180801)
A61K 39/001132 (20180801)
A61K 39/001151 (20180801)
A61K 39/001156 (20180801)
A61K 39/001157 (20180801)
A61K 39/001162 (20180801)
A61K 39/001164 (20180801)
A61K 39/001166 (20180801)
A61K 39/001176 (20180801)
A61K 39/001181 (20180801)
A61K 39/001182 (20180801)
A61K 39/001184 (20180801)
A61K 39/001186 (20180801)
A61K 39/001188 (20180801)
A61K 39/001189 (20180801)
A61K 39/001191 (20180801)
A61K 39/001192 (20180801)
A61K 39/001193 (20180801)
A61K 39/001194 (20180801)
A61K 39/001195 (20180801)
A61K 39/001197 (20180801)
A61K 45/06 (20130101)
A61K 47/554 (20170801)
A61K 47/6917 (20170801)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/3515 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833198 Tan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Children's Hospital Medical Center (Cincinnati, Ohio)
ASSIGNEE(S) CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio)
INVENTOR(S) Ming Tan (Cincinnati, Ohio);  Xi Jason Jiang (Cincinnati, Ohio)
ABSTRACT Disclosed herein are vaccine compositions, in particular, polyvalent icosahedral compositions for antigen presentation. The disclosed compositions may contain an S particle made up of recombinant fusion proteins. The recombinant fusion proteins may include a norovirus (NoV) S domain protein, a linker protein domain operatively connected to the norovirus S domain protein, and an antigen protein domain operatively connected to said linker.
FILED Thursday, March 15, 2018
APPL NO 16/489095
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 39/385 (20130101)
A61K 2039/64 (20130101)
A61K 2039/70 (20130101)
A61K 2039/6075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 14/005 (20130101)
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/16022 (20130101)
C12N 2770/16034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833199 Khurana
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Silver Spring, Maryland)
INVENTOR(S) Surender Khurana (Clarksburg, Maryland)
ABSTRACT Isolated peptides comprising one or more antigenic sites of filovirus glycoprotein and methods of their use and production are disclosed. Nucleic acid molecules encoding the peptides are also provided. In several embodiments, the peptides can be used to induce an immune response to filovirus glycoprotein, such as Zaire ebolavirus glycoprotein, in a subject, for example, to treat or prevent infection of the subject with the virus.
FILED Tuesday, November 16, 2021
APPL NO 17/527968
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/6081 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2760/14122 (20130101)
C12N 2760/14134 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101)
G01N 2469/20 (20130101)
G01N 2800/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833255 Chopra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Massachusetts Institute Of Technology (Cambridge, Massachusetts)
INVENTOR(S) Sunandini Chopra (Cambridge, Massachusetts);  Rohit Karnik (Cambridge, Massachusetts);  Amy Wang (Cambridge, Massachusetts);  Omid C. Farokhzad (Waban, Massachusetts);  Xue-Qing Zhang (Livingston, New Jersey)
ABSTRACT Provided is a nanoparticle comprising a pH-responsive polymer, a pH-insensitive polymer and a payload molecule. The nanoparticle can act as a system for delivery of the payload that releases the payload in a pH sensitive manner.
FILED Friday, October 07, 2016
APPL NO 15/766706
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/5138 (20130101)
A61K 9/5146 (20130101)
A61K 9/5153 (20130101) Original (OR) Class
A61K 38/28 (20130101)
A61K 47/6803 (20170801)
A61K 47/6933 (20170801)
A61K 47/6937 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)
A61P 35/00 (20180101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833256 Iwamoto et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) University Of Maryland, Baltimore (Baltimore, Maryland);  Children's Hospital Of Philadelphia (Philadelphia, Pennsylvania)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland);  The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania)
INVENTOR(S) Masahiro Iwamoto (Baltimore, Maryland);  Michael Chorny (Huntingdon Valley, Pennsylvania)
ABSTRACT The invention relates to compositions and methods as part of a pharmacotherapeutic strategy that targets the endochondral ossification process in a pharmacologically selective and site-specific manner. A variety of orthopedic pathologies are caused by or associated with generalized or local dysregulation of endochondral ossification, for example trauma to the bone growth plate or diaphysis can cause a serious imbalance in bone growth, leading to progressive deformity that today can only be treated surgically. Dysregulated endochondral ossification is also behind heterotopic ossification, which arises in soft tissues and causes pain, decrease in mobility and other clinical problems. The invention therefore provides RARy agonist and antagonist nanoparticle compositions for treating abnormal endochondral ossification and bone growth that can deliver robust local therapeutic control over a particular long bone's growth with a long-lasting effect.
FILED Wednesday, June 20, 2018
APPL NO 16/622366
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/19 (20130101)
A61K 9/5153 (20130101)
A61K 9/5192 (20130101) Original (OR) Class
A61K 31/192 (20130101)
A61K 31/415 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/08 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833309 Gillerman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Third Pole, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Third Pole, Inc. (Waltham, Massachusetts)
INVENTOR(S) Ian J. Gillerman (Somerville, Massachusetts);  Gregory W. Hall (Belmont, Massachusetts);  Wolfgang Scholz (Beverly, Massachusetts);  David G. Zapol (San Francisco, California)
ABSTRACT Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.
FILED Thursday, June 30, 2022
APPL NO 17/855592
ART UNIT 3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 33/00 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 16/04 (20130101)
A61M 16/12 (20130101) Original (OR) Class
A61M 16/022 (20170801)
A61M 16/024 (20170801)
A61M 16/0057 (20130101)
A61M 16/0093 (20140204)
A61M 16/101 (20140204)
A61M 16/107 (20140204)
A61M 16/202 (20140204)
A61M 16/0666 (20130101)
A61M 2202/0275 (20130101)
A61M 2202/0283 (20130101)
A61M 2205/05 (20130101)
A61M 2205/054 (20130101)
A61M 2205/80 (20130101)
A61M 2205/125 (20130101)
A61M 2205/502 (20130101)
A61M 2205/3584 (20130101)
A61M 2205/8206 (20130101)
A61M 2209/088 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 21/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833346 Park et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Hongkun Park (Cambridge, Massachusetts);  Donhee Ham (Cambridge, Massachusetts);  Jeffrey T. Abbott (Cambridge, Massachusetts);  Ling Qin (Cambridge, Massachusetts);  Marsela Jorgolli (Cambridge, Massachusetts);  Tianyang Ye (Cambridge, Massachusetts)
ABSTRACT The present invention generally relates to nanowires. In one aspect, the present invention is generally directed to systems and methods of individually addressing nanowires on a surface, e.g., that are substantially upstanding or vertically-oriented with respect to the surface. In some cases, one or more nanowires may be individually addressed using various integrated circuit (“IC”) technologies, such as CMOS. For example, the nanowires may form an array on top of an active CMOs integrated circuit.
FILED Friday, January 08, 2021
APPL NO 17/144387
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/05 (20130101)
A61N 1/06 (20130101)
A61N 1/0531 (20130101) Original (OR) Class
A61N 1/0536 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/48 (20130101)
H01L 23/49 (20130101)
H01L 29/0676 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/14 (20130101)
H01L 2924/10253 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833371 Sheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California);  Radiabeam Systems, LLC (Santa Monica, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Radiabeam Systems, LLC (Santa Monica, California)
INVENTOR(S) Ke Sheng (Los Angeles, California);  Salime M. Boucher (Santa Monica, California)
ABSTRACT A radiotherapy system and method for delivering radiotherapy are provided. In some aspects, the radiotherapy system includes beam director comprising a radiation source configured to generate radiation for irradiating a patient, the beam director having at least four degrees of freedom of movement. The radiotherapy system also includes a controller configured to operate the beam director to irradiate the patient in accordance with a radiation treatment plan, wherein the radiation treatment plan is generated based on a solution space determined by the at least four degrees of freedom of movement of the beam director.
FILED Monday, June 07, 2021
APPL NO 17/341076
ART UNIT 2884 — Optics
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1031 (20130101)
A61N 5/1083 (20130101) Original (OR) Class
A61N 2005/0626 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833508 Han et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Jongyoon Han (Bedford, Massachusetts);  Hyungkook Jeon (Cambridge, Massachusetts)
ABSTRACT Described is a multi-dimensional double spiral (MDDS) microfluidic device comprising a first spiral microchannel and a second microchannel, wherein the wherein the first spiral microchannel and second spiral microchannel have different cross-sectional areas. Also described is a device comprising a multi-dimensional double spiral and system for recirculation. The invention also encompasses methods of separating particles from a sample fluid comprising a mixture of particles comprising the use of the multi-dimensional double spiral microfluidic device.
FILED Wednesday, September 29, 2021
APPL NO 17/488463
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5027 (20130101) Original (OR) Class
B01L 2200/0652 (20130101)
B01L 2300/0809 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0883 (20130101)
B01L 2400/0487 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833742 You et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Child Health and Human Development (NICHD)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Shangting You (La Jolla, California);  Shaochen Chen (San Diego, California)
ABSTRACT A method and system for microscale 3D printing achieve high-fidelity fabrication through the control of the light exposure time. A single pulse of light is used to initiate polymerization of a pre-polymer solution to minimize scattering-induced resolution deterioration. The printed object is fabricated in a layer-by-layer construction where each layer is formed through exposure to a single light pulse.
FILED Monday, June 28, 2021
APPL NO 17/360891
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/129 (20170801) Original (OR) Class
B29C 64/232 (20170801)
B29C 64/245 (20170801)
B29C 64/273 (20170801)
B29C 64/286 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834392 Woster et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina)
ASSIGNEE(S) MUSC Foundation for Research Development (Charleston, North Carolina)
INVENTOR(S) Patrick M. Woster (Charleston, South Carolina);  Joy E. Kirkpatrick (Charleston, South Carolina)
ABSTRACT The invention relates to KDM4B inhibitors, compositions comprising an effective amount of KDM4B inhibitors and methods for treating inflammatory diseases and disorders.
FILED Thursday, June 04, 2020
APPL NO 16/956871
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 235/38 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834401 Robinson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S) Douglas Robinson (Towson, Maryland);  Alexandra Surcel (Baltimore, Maryland);  Win Pin Ng (Berkeley, California);  Caren L. Freel Meyers (Towson, Maryland)
ABSTRACT Described are methods of treating or preventing a disease in a subject treatable by modulating cell mechanics. The method includes administering to a subject having or at risk for such a disease a pharmaceutical composition. comprising an agent selected from the group comprising a salt, solvate, or stereoisomer of compound (VIII) or its derivatives or a mixture of their constituents, where the compound has the formula:
FILED Monday, July 06, 2020
APPL NO 16/921318
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/12 (20130101)
A61K 31/12 (20130101)
A61K 31/15 (20130101)
A61K 31/15 (20130101)
A61K 31/27 (20130101)
A61K 31/27 (20130101)
A61K 31/136 (20130101)
A61K 31/136 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 49/825 (20130101) Original (OR) Class
C07C 251/80 (20130101)
C07C 271/58 (20130101)
C07C 275/30 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2333/44 (20130101)
G01N 2333/4712 (20130101)
G01N 2500/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834404 Piazza et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNIVERSITY OF SOUTH ALABAMA (Mobile, Alabama)
ASSIGNEE(S) University of South Alabama (Mobile, Alabama)
INVENTOR(S) Gary Piazza (Daphne, Alabama);  Xi Chen (Hoover, Alabama);  Herbert Weissbach (Boynton Beach, Florida);  Shailaja Kesraju Allani (Boynton Beach, Florida)
ABSTRACT The disclosure provides chemical compounds possessing therapeutic and/or protective properties against oxidative damage. Methods of making such therapeutic and/or protective compounds and associated compositions are also provided, as are methods for their use, which include protecting cells from oxidative damage and/or inhibiting production of ROS in a cell or subject, as well as preventing or reducing the extent of tissue damage caused by an ischemic event in a subject at elevated risk of such an event.
FILED Monday, November 15, 2021
APPL NO 17/526742
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Acyclic or Carbocyclic Compounds
C07C 59/72 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834408 Ghosh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Arun K. Ghosh (West Lafayette, Indiana);  Monika Yadav (West Lafayette, Indiana);  Andrew Mesecar (West Lafayette, Indiana)
ABSTRACT Inhibitors of SARS-CoV-2 (COVID), pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.
FILED Thursday, May 26, 2022
APPL NO 17/826061
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 207/26 (20130101) Original (OR) Class
C07D 227/087 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834411 Batchelor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) NovaTarg, Inc. (Research Triangle Park, North Carolina)
ASSIGNEE(S) NovaTarg, Inc. (Research Triangle Park, North Carolina)
INVENTOR(S) Kenneth Batchelor (Wilmington, North Carolina);  Jeffery E. Cobb (Chapel Hill, North Carolina);  Kristjan S. Gudmundsson (Raleigh, North Carolina);  Brad R. Henke (Cary, North Carolina);  Francis X. Tavares (Durham, North Carolina)
ABSTRACT The present invention provides novel fused bicyclic alkylene linked imidodicarbonimidic diamides. In particular, described herein are N-[2-(indol-3-yl)alkylene]-linked imidodicarbonimidic diamides and N-[2-(pyrrolopyridin-3-yl)alkylene]-linked imidodicarbonimidic diamides (compound of formula (I) or formula (II)), and uses therefor. The compounds of the present invention are believed to be organic cation transporter selective compounds, useful for the treatment of diseases and conditions caused by reduced activity of 5′ adenosine monophosphate-activated protein kinase (AMPK).
FILED Tuesday, January 18, 2022
APPL NO 17/578050
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)

Heterocyclic Compounds
C07D 209/20 (20130101) Original (OR) Class
C07D 209/32 (20130101)
C07D 471/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834416 Goodson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Board of Trustees of Southern Illinois University (Carbondale, Illinois);  Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Board of Trustees of Southern Illinois University (Carbondale, Illinois);  Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Boyd M. Goodson (Carbondale, Illinois);  Eduard Y. Chekmenev (Troy, Michigan);  Bryce E. Kidd (Carbondale, Illinois);  Jamil A. Mashni (Carbondale, Illinois);  Miranda Limbach (Creal Springs, Illinois);  Yuqing Hou (Carbondale, Illinois);  Fan Shi (Houston, Texas)
ABSTRACT The present disclosure is directed to a cleavable agent for enhanced magnetic resonance generally corresponding to the formula Y-L-R, wherein Y represents a catalyst-binding moiety having at least one isotopically labeled heteroatom, L represents a cleavable bond, and R represents a hyperpolarized payload having at least one isotopically labeled carbon. Also disclosed herein is a method of cleaving the cleavable agent for enhanced magnetic resonance.
FILED Wednesday, November 27, 2019
APPL NO 16/698332
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/12 (20130101)
B01J 2531/827 (20130101)

Heterocyclic Compounds
C07D 213/46 (20130101)
C07D 213/63 (20130101)
C07D 233/60 (20130101) Original (OR) Class
C07D 241/12 (20130101)
C07D 401/06 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/6506 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/46 (20130101)
G01R 33/282 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834418 Resnick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) BIOHAVEN THERAPEUTICS LTD. (New Haven, Connecticut)
ASSIGNEE(S) Biohaven Therapeutics Ltd. (Tortola, Virgin Islands)
INVENTOR(S) Lynn Resnick (Pittsburgh, Pennsylvania);  George T. Topalov (Pittsburgh, Pennsylvania);  Justin K. Belardi (Pittsburgh, Pennsylvania);  James S. Hale (Pittsburgh, Pennsylvania);  Scott S. Harried (Pittsburgh, Pennsylvania);  Charles A. Flentge (Mars, Pennsylvania);  David A. Mareska (McMurray, Pennsylvania)
ABSTRACT Optionally substituted benzoimidazol-1,2-yl amides, such as compounds of Formula 1 or Formula 2, can be used to treat disorders associated with a Kv7 potassium channel activator. Compositions, medicaments, and dosage forms related to the treatment are also disclosed herein.
FILED Friday, December 18, 2020
APPL NO 17/127231
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 235/30 (20130101) Original (OR) Class
C07D 401/04 (20130101)
C07D 401/12 (20130101)
C07D 403/04 (20130101)
C07D 405/12 (20130101)
C07D 413/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834424 Cuervo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York)
ASSIGNEE(S) ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York)
INVENTOR(S) Ana Maria Cuervo (Bronx, New York);  Evripidis Gavathiotis (Bronx, New York)
ABSTRACT Compounds and pharmaceutically acceptable salts thereof of Formula I are disclosed. Certain compounds and salts of Formula I are active as CMA modulators. The disclosure provides pharmaceutical compositions containing a compound of Formula I.
FILED Thursday, August 30, 2018
APPL NO 17/270522
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 241/42 (20130101)
C07D 265/36 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834451 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Jun Wang (Tucson, Arizona);  Naoya Kitamura (Tucson, Arizona)
ABSTRACT This invention is in the field of medicinal chemistry and relates to a new class of small-molecules having a pyrazolopyridine (or similar) structure (e.g.,
Formula I) which function as inhibitors of the viral protein 2C protein activity and/or expression, and which function as therapeutics for the treatment of viral infection characterized with viral protein 2C activity and/or expression (e.g., non-polio enterovirus infection) (e.g., enterovirus D68 (EV-D68) infection, enterovirus A71 (EV-A71) infection, and coxsackievirus B3 (CVB3) infection.
FILED Monday, March 28, 2022
APPL NO 17/705984
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 471/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834456 Mulcahy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) SITEONE THERAPEUTICS, INC. (South San Francisco, California);  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
ASSIGNEE(S) SITEONE THERAPEUTICS, INC. (Bozeman, Montana);  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S) John Mulcahy (Redwood City, California);  Hassan Pajouhesh (Mountain View, California);  George Miljanich (Redwood City, California);  Anton Delwig (Albany, California);  Jacob Beckley (Bozeman, Montana);  Grant Masaaki Shibuya (South San Francisco, California);  Justin Du Bois (Menlo Park, California)
ABSTRACT Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating conditions associated with voltage-gated sodium channel function where the compounds are 11,13-modified saxitoxins according to Formula (I): where R4, R4a, R7, R7a, and X2 are as described herein.
FILED Wednesday, January 26, 2022
APPL NO 17/585530
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 487/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834462 Han et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Crinetics Pharmaceuticals, Inc. (San Diego, California)
ASSIGNEE(S) CRINETICS PHARMACEUTICALS, INC. (San Diego, California)
INVENTOR(S) Sangdon Han (San Diego, California);  Sun Hee Kim (San Diego, California);  Yunfei Zhu (San Diego, California)
ABSTRACT Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity.
FILED Wednesday, April 06, 2022
APPL NO 17/714825
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/08 (20130101)
A61K 9/2013 (20130101)
A61K 9/2054 (20130101)
A61K 9/4825 (20130101)

Heterocyclic Compounds
C07D 401/14 (20130101)
C07D 498/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834470 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
V Foundation for Cancer Research (VFCR)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Yong Zhang (Los Angeles, California);  Zhefu Dai (Los Angeles, California);  Xiao-Nan Zhang (Los Angeles, California)
ABSTRACT This disclosure provides a method of synthesis of 4′-thioribose NAD+ and analogues thereof, using an efficient chemoenzymatic approach. Also provided are methods of inhibiting the CD38 enzyme and compounds including 4′-thioribose NAD+ and compounds related thereto.
FILED Friday, October 04, 2019
APPL NO 17/281424
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7076 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/20 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834474 Gao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Guangping Gao (Worcester, Massachusetts);  Terence Flotte (Worcester, Massachusetts);  Jun Xie (Worcester, Massachusetts)
ABSTRACT The invention in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the invention relates to gene transfer methods using the recombinant adeno-associate viruses. In some aspects, the invention relates to isolated AAV capsid proteins and isolated nucleic acids encoding the same.
FILED Friday, May 08, 2020
APPL NO 16/870816
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 35/76 (20130101)
A61K 48/00 (20130101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14145 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834476 Beernink
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Children's Hospital and Research Center at Oakland (Oakland, California)
ASSIGNEE(S) Children's Hospital and Research Center at Oakland (Oakland, California)
INVENTOR(S) Peter T. Beernink (Walnut Creek, California)
ABSTRACT Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
FILED Wednesday, October 07, 2020
APPL NO 17/065386
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/095 (20130101)
A61K 2039/575 (20130101)
A61K 2039/55505 (20130101)

Peptides
C07K 14/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834479 Romesberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
INVENTOR(S) Floyd E. Romesberg (La Jolla, California);  Yorke Zhang (San Diego, California)
ABSTRACT Disclosed herein are proteins, methods, cells, engineered microorganisms, and kits for generating a modified nucleoside triphosphate transporter from Phaeodactylum tricornutum. Also disclosed herein proteins, methods, cells, engineered microorganisms, and kits for production of a nucleic acid molecule that comprises an unnatural nucleotide utilizing a modified nucleoside triphosphate transporter from Phaeodactylum tricornutum.
FILED Friday, April 03, 2020
APPL NO 16/839741
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/405 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/10 (20130101)
C12N 15/11 (20130101)
C12N 15/90 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834489 Blanchard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York);  THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
INVENTOR(S) Scott C. Blanchard (Ithaca, New York);  Gabriel Glenn Gregorio (Ithaca, New York);  Brian Kobilka (Ithaca, New York)
ABSTRACT Disclosed herein are methods for providing a molecular efficacy of a ligand, especially when utilizing single-molecule fluorescence resonance energy transfer (“smFRET”) imaging, as well as compounds useful in such methods.
FILED Friday, August 31, 2018
APPL NO 16/642181
ART UNIT 1678 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/70571 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6408 (20130101)
G01N 33/542 (20130101)
G01N 33/582 (20130101)
G01N 33/9433 (20130101)
G01N 2021/6421 (20130101)
G01N 2333/4719 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834494 Diamond et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Michael S. Diamond (St. Louis, Missouri);  Daved Fremont (St. Louis, Missouri);  Haiyan Zhao (St. Louis, Missouri);  Estefania Fernandez (St. Louis, Missouri);  Derek Platt (St. Louis, Missouri);  Christopher Nelson (St. Louis, Missouri)
ABSTRACT The present disclosure relates to antibodies specific to Zika virus and methods for detecting Zika virus infection in a subject. The present disclosure also relates to therapeutic antibodies useful in reducing viral load.
FILED Wednesday, July 26, 2017
APPL NO 16/320872
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/1081 (20130101) Original (OR) Class
C07K 2317/34 (20130101)
C07K 2317/55 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/622 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101)
G01N 2333/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834497 Tucker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) INTEGRAL MOLECULAR, INC. (Philadelphia, Pennsylvania)
ASSIGNEE(S) INTEGRAL MOLECULAR, INC. (Philadelphia, Pennsylvania)
INVENTOR(S) David F. Tucker (Medford, Massachusetts);  Kimberly-Anne Mattia (Plymouth Meeting, Pennsylvania);  Christine R. Fisher (Sommerville, Massachusetts);  Benjamin J. Doranz (Philadelphia, Pennsylvania);  Joseph B. Rucker (Philadelphia, Pennsylvania)
ABSTRACT Antibodies and compositions against GLUT4 and uses thereof are provided herein.
FILED Tuesday, April 30, 2019
APPL NO 17/051241
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)

Peptides
C07K 14/705 (20130101)
C07K 16/28 (20130101) Original (OR) Class
C07K 2317/77 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834509 Qin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Haiying Qin (Potomac, Maryland);  Terry J. Fry (Bethesda, Maryland)
ABSTRACT The invention provides a chimeric antigen receptor (CAR) comprising an antigen binding domain specific for TSLPR, a transmembrane domain, and an intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of a proliferative disorder, e.g., cancer, in a mammal and methods of treating or preventing a proliferative disorder, e.g., cancer, in a mammal are also disclosed.
FILED Tuesday, April 28, 2020
APPL NO 16/860216
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/7051 (20130101)
C07K 14/7151 (20130101)
C07K 14/70517 (20130101)
C07K 16/2803 (20130101)
C07K 16/2866 (20130101) Original (OR) Class
C07K 16/3061 (20130101)
C07K 2317/524 (20130101)
C07K 2317/526 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2319/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834511 Press et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Fred Hutchinson Cancer Center (Seattle, Washington)
ASSIGNEE(S) Fred Hutchinson Cancer Center (Seattle, Washington)
INVENTOR(S) Oliver Press (Seattle, Washington);  Brian Till (Seattle, Washington)
ABSTRACT The present disclosure provides compositions and uses thereof for treating a disease or disorder associated with CD20 expression. Treatments of this disclosure include use of a host cell expressing a fusion protein, such as an anti-CD20 CAR, optionally in combination with a CD20-specific binding molecule, a chemotherapeutic, an inhibitor of an immunosuppression component, or combinations thereof.
FILED Tuesday, November 24, 2020
APPL NO 17/103762
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 39/001124 (20180801)
A61K 39/39541 (20130101)
A61K 39/39558 (20130101)
A61K 39/39558 (20130101)
A61K 2039/505 (20130101)
A61K 2039/507 (20130101)
A61K 2039/5156 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/7051 (20130101)
C07K 14/70521 (20130101)
C07K 16/2887 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/73 (20130101)
C07K 2317/622 (20130101)
C07K 2319/03 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834512 Deb
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Arjun Deb (Los Angeles, California)
ABSTRACT In certain aspects, provided herein are inhibitory anti-ENPP1 antibodies and antigen binding fragments thereof. In some aspects, provided herein are methods of treating myocardial infarction using the antibodies provided herein. In certain aspects, provided herein are nucleic acid molecules encoding the antibodies provided herein, host cells comprising such nucleic acids, and methods of making the antibodies provided herein using such host cells. In some aspects, also provided herein are pharmaceutical compositions comprising the antibodies provided herein.
FILED Monday, May 03, 2021
APPL NO 17/306544
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Peptides
C07K 16/40 (20130101)
C07K 16/2896 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/52 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834513 Spriggs et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Memorial Sloan Kettering Cancer Center (New York, New York)
ASSIGNEE(S) Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S) David Spriggs (New York, New York);  Dharmarao Thapi (Bayside Hills, New York)
ABSTRACT The invention provides antibodies, and antigen-binding fragments thereof, that specifically bind to a polypeptide, or antigenic portion thereof, wherein the polypeptide is selected from a) MUC16 ectodomain polypeptide, b) MUC16 cytoplasmic domain polypeptide, and c) MUC16 extracellular domain polypeptide that contains a cysteine loop polypeptide. The invention's antibodies and compositions containing them are useful in diagnostic and therapeutic applications for diseases in which MUC16 is overexpressed, such as cancer.
FILED Tuesday, July 28, 2020
APPL NO 16/941348
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00117 (20180801)
A61K 2039/505 (20130101)
A61K 2039/5156 (20130101)

Peptides
C07K 16/3092 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/33 (20130101)
C07K 2317/34 (20130101)
C07K 2317/77 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/33 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57488 (20130101)
G01N 2333/705 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834515 Lin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) CORNELL UNIVERSITY (Ithaca, New York);  TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE (New York, New York)
ASSIGNEE(S) CORNELL UNIVERSITY (Ithaca, New York);  TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE (New York, New York)
INVENTOR(S) Gang Lin (Forest Hills, New York);  Carl Nathan (Larchmont, New York);  Laura Kirkman (New York, New York);  Wenhu Zhan (Elmhurst, New York);  Trevor Morgan (Royston, United Kingdom);  Kenjiro Sato (Kanagawa, Japan);  Ryoma Hara (Tokyo, Japan);  Masanori Kawasaki (Tokyo, Japan);  Toshihiro Imaeda (Kanagawa, Japan);  Akinori Toita (Kanagawa, Japan);  Rei Okamoto (Kanagawa, Japan);  Takafumi Yukawa (Kanagawa, Japan);  Kazuyoshi Aso (Kanagawa, Japan);  Tzu-Tshin Wong (Acton, Massachusetts);  John D. Ginn (New Milford, Connecticut);  Michael A. Foley (New York, New York)
ABSTRACT The compounds of the present invention are represented by the following compounds having Formula I and Formula (I′): where the substituents R1, R2, R2′, R3, R4, R5, R′, R″, X, Y, and Z are as defined herein and where the substituents R1, R2, R3, R4, R5, R′, R″, X, Y, and Z are as defined herein. These compounds are used in the treatment of bacterial infections, parasite infections, fungal infections, cancer, immunologic disorders, autoimmune disorders, neurodegenerative diseases and disorders, inflammatory disorders, or muscular dystrophy or for providing immunosuppression for transplanted organs or tissues.
FILED Thursday, October 11, 2018
APPL NO 16/755482
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/06 (20180101)

Peptides
C07K 5/0215 (20130101) Original (OR) Class
C07K 11/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834517 He et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) BRANDEIS UNIVERSITY (Waltham, Massachusetts)
ASSIGNEE(S) BRANDEIS UNIVERSITY (Waltham, Massachusetts)
INVENTOR(S) Hongjian He (Waltham, Massachusetts);  Bing Xu (Newton, Massachusetts)
ABSTRACT The present invention relates to a branched peptide that includes a first peptide chain and a second peptide chain having its C-terminal amino acid covalently linked to a sidechain of an amino acid residue of the first peptide chain, wherein the first peptide chain includes a plurality of aromatic amino acids and, optionally, an aromatic group linked to an amino terminus of the first peptide chain; and the second peptide chain includes a plurality of hydrophilic amino acids and an enzyme cleavage site. Pharmaceutical compositions containing the branched peptide and one or more therapeutic agents in an aqueous medium are disclosed, where the branched peptides form micelle structures in the aqueous medium. Methods of using the pharmaceutical composition to deliver therapeutic agents, and for treating various disease conditions are also described.
FILED Monday, November 29, 2021
APPL NO 17/537418
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)
A61P 35/00 (20180101)

Peptides
C07K 7/06 (20130101) Original (OR) Class
C07K 7/08 (20130101)
C07K 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834520 Walensky et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Loren D. Walensky (Newton, Massachusetts);  Gregory H. Bird (Pelham, New Hampshire);  Rachel Guerra (Cambridge, Massachusetts);  Edward Harvey (Weston, Massachusetts)
ABSTRACT This disclosure features structurally-stabilized and/or cysteine-reactive peptide inhibitors for selective targeting of BFL-1, or dual targeting of BFL-1 and MCL-1. Also disclosed are methods of using such structurally-stabilized and cysteine-reactive peptides in the treatment of BFL-1- and/or MCL-1-expressing or -dependent cancers or diseases of cellular excess (e.g., autoimmune or inflammatory conditions). Also provided are combination therapies comprising such structurally-stabilized and/or cysteine-reactive peptides and inhibitors of the DNA damage response pathway, such as an ATM kinase inhibitor, ATR kinase inhibitor, CHK1/2 inhibitor, or PARP inhibitor; or an inhibitor of MCL-1, or a selective inhibitor of BCL-2, or an inhibitor of BCL-2/BCL-XL, for the treatment of BFL-1-expressing or -dependent cancers (e.g., AML), BFL-1 and MCL-1-expressing or -dependent cancers, or diseases of cellular excess (e.g., autoimmune or inflammatory conditions).
FILED Thursday, December 13, 2018
APPL NO 16/766201
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834649 Friedland et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) EDITAS MEDICINE, INC. (Cambridge, Massachusetts)
ASSIGNEE(S) EDITAS MEDICINE, INC. (Cambridge, Massachusetts)
INVENTOR(S) Ari E. Friedland (Boston, Massachusetts);  Penrose O'Donnell (Yarmouth, Maine);  David A. Bumcrot (Belmont, Massachusetts)
ABSTRACT CRISPR/CAS-related systems, compositions and methods for editing RS1, RL2, and/or LAT genes in human cells are described, as are cells and compositions including cells edited according to the same.
FILED Monday, April 19, 2021
APPL NO 17/234145
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/102 (20130101)
C12N 15/1133 (20130101) Original (OR) Class
C12N 2310/10 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834652 Acar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Murat Acar (New Haven, Connecticut);  Gregory Elison (New Haven, Connecticut)
ABSTRACT The present invention includes compositions and methods for promoting scarless genome editing in a cell. In one aspect, methods of the invention utilize the CRISPR/Cas9 system to introduce a cut site into a genomic location to be edited. In another aspect, methods of the invention integrate an edited sequence into that genomic location in a scarless manner.
FILED Wednesday, November 08, 2017
APPL NO 16/348092
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/81 (20130101)
C12N 15/102 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834653 Elledge et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Stephen Elledge (Brookline, Massachusetts);  Tomasz Kula (Brookline, Massachusetts);  Mohammad Haj Dezfulian (Boston, Massachusetts)
ABSTRACT Described herein, in one aspect, are antigen presenting cells (APCs) comprising an exogenous nucleic acid encoding one or more candidate antigens, wherein the one or more candidate antigens are expressed and presented with MHC class I or MC class II molecules; a molecular reporter of Granzyme B (GzB) activity; and c) an exogenous inhibitor of caspase-activated deoxyribonuclease (CAD)-mediated DNA degradation, a CAD knockout, or a caspase knockout (e.g., caspase 3 knockout). Described herein, in another aspect, is a system for detection of recognized antigen presentation by an antigen presenting cell to a cytotoxic lymphocyte or NK cell.
FILED Friday, June 08, 2018
APPL NO 16/619859
ART UNIT 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 5/0693 (20130101)
C12N 15/1037 (20130101) Original (OR) Class
C12N 2529/10 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 20/04 (20130101)
C40B 40/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5047 (20130101)
G01N 2333/96436 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834657 Dunham
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Southern California (Los Angeles, California);  SeqOnce Biosciences Inc. (La Canada-Flintridge, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California);  SeqOnce Biosciences Inc. (La Canada-Flintridge, California)
INVENTOR(S) Joseph Dunham (El Segundo, California)
ABSTRACT The disclosure provides for single amplification and double amplification methods for preparing nucleic acid samples for sequencing.
FILED Tuesday, June 12, 2018
APPL NO 16/006354
ART UNIT 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1093 (20130101) Original (OR) Class
C12N 15/1093 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 2521/327 (20130101)
C12Q 2521/531 (20130101)
C12Q 2525/121 (20130101)
C12Q 2525/191 (20130101)
C12Q 2563/179 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 50/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834659 Weiss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ron Weiss (Newton, Massachusetts);  Giulio Alighieri (Cambridge, Massachusetts)
ABSTRACT The present disclosure, at least in part, relates to an engineered RNA (e.g., microRNA and sgRNA), in the absence of an input signal, that is engineered to have a large enough energy gap between the formations of a first secondary structure, which is unrecognizable by an actuator, and a second secondary structure, which is recognizable by an actuator (e.g., Drosha and Cas protein).
FILED Friday, September 25, 2020
APPL NO 17/032233
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2310/122 (20130101)
C12N 2310/141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834676 Sentman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Charles L. Sentman (Grantham, New Hampshire)
ABSTRACT The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same.
FILED Tuesday, June 21, 2022
APPL NO 17/844982
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 39/0011 (20130101)
A61K 2035/124 (20130101)
A61K 2039/585 (20130101)
A61K 2039/5156 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101) Original (OR) Class
C12N 2501/515 (20130101)
C12N 2510/02 (20130101)
C12N 2511/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834689 Ptacin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) SYNTHORX, INC. (La Jolla, California);  THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California);  SYNTHORX, INC. (La Jolla, California)
INVENTOR(S) Jerod Ptacin (La Jolla, California);  Carolina Caffaro (La Jolla, California);  Hans Aerni (La Jolla, California);  Yorke Zhang (La Jolla, California);  Emil C. Fischer (La Jolla, California);  Aaron W. Feldman (La Jolla, California);  Vivian T. Dien (La Jolla, California);  Floyd E. Romesberg (La Jolla, California)
ABSTRACT Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
FILED Tuesday, March 09, 2021
APPL NO 17/196151
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/93 (20130101) Original (OR) Class
C12N 15/90 (20130101)
C12N 15/113 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/02 (20130101)

Enzymes
C12Y 601/01026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834692 Nair et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Wisconsin)
INVENTOR(S) Nikhil U. Nair (Medford, Massachusetts);  Josef R. Bober (Medford, Massachusetts)
ABSTRACT Disclosed are components and methods for preparing tagatose from galactose via isomerization reactions using engineered components. The engineered components include microbial cells and methods for preparing microbial cells that have been engineered to catalyze isomerization of galactose to tagatose, in which the microbial cells express cytoplasmically an exogenous L-arabinose isomerase enzyme. The disclosed microbial cells may further be modified for use in methods for preparing tagatose from galactose via isomerization reactions where the microbial cells are treated with reagents that permeabilize the cells. The disclosed methods enable isomerization reactions of galactose to tagatose at relatively high rates, high conversions, and elevated temperatures.
FILED Friday, February 05, 2021
APPL NO 17/168499
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/90 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/02 (20130101)
C12P 19/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834712 Xie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Xiaoliang Sunney Xie (Lexington, Massachusetts);  Katsuyuki Shiroguchi (Arlington, Massachusetts);  Peter A. Sims (Cambridge, Massachusetts);  Tony Z. Jia (Cambridge, Massachusetts)
ABSTRACT Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided.
FILED Thursday, March 02, 2023
APPL NO 18/177496
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101)
C12N 2320/10 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6853 (20130101)
C12Q 1/6853 (20130101)
C12Q 1/6874 (20130101) Original (OR) Class
C12Q 2525/131 (20130101)
C12Q 2525/301 (20130101)
C12Q 2537/16 (20130101)
C12Q 2563/179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834721 Alland et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S) David Alland (Bernardsville, New Jersey);  Soumitesh Chakravorty (Somerset, New Jersey)
ABSTRACT This invention relates to nucleic acids, reagents and methods for detecting Rifampicin-resistant Mycobacterium tuberculosis in a sample from a subject. In one aspect, the invention provides methods of detecting Rifampicin resistant M. tuberculosis in a sample comprising (a) amplifying a nucleic acid containing the rifampicin resistance determining region (RRDR) of the rpoB gene in a sample to provide an amplified nucleic acid; (b) probing the amplified nucleic acid with at least three molecular beacon probes for an RRDR mutant target; (c) conducting melting temperature (Tm) analysis to determine a Tm value for each probe; and (d) comparing the Tm value for each probe with a Tm value for a wild-type RRDR region, wherein a Tm value for at least one of the molecular beacon probes that is greater than the Tm value for the wild-type RRDR indicates the presence of rifampicin resistant M. tuberculosis in the sample.
FILED Thursday, May 14, 2020
APPL NO 16/874177
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834723 Storch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Gregory A Storch (St. Louis, Missouri);  Todd N. Wylie (St. Louis, Missouri);  Kristine M. Wylie (St. Louis, Missouri)
ABSTRACT The present disclosure is directed to improved methods and compositions for the detection of enterovirus D68.
FILED Wednesday, July 22, 2020
APPL NO 16/935761
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/701 (20130101) Original (OR) Class
C12Q 1/6806 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835499 Synold et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CITY OF HOPE (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Timothy W. Synold (Monrovia, California);  John Termini (Altadena, California);  Sarah Shuck (Orange, California)
ABSTRACT Methods of quantifying a N2-(1-carboxyethyl)-2′-deoxyguanosine (CEdG) and N2-(1-carboxyethyl)-guanosine (CEG) levels in biological samples and comparing those levels to known normal levels can diagnose a number of metabolic disorders or complications associated therewith, including diabetes, its associated complications, and cancer. Methods can also determine whether therapies for disorders are effective by measuring CEdG and CEG levels before and after treatment. Measurement of CEdG and CEG levels is achieved by using liquid chromatography electrospray ionization tandem mass spectrometry.
FILED Friday, July 31, 2020
APPL NO 16/944640
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/28 (20130101)
G01N 30/7266 (20130101) Original (OR) Class
G01N 33/49 (20130101)
G01N 33/493 (20130101)
G01N 33/4833 (20130101)
G01N 2001/2893 (20130101)
G01N 2030/027 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835503 Hazen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Cleveland Clinic Foundation (Cleveland, Ohio)
ASSIGNEE(S) The Cleveland Clinic Foundation (Cleveland, Ohio)
INVENTOR(S) Stanley L. Hazen (Pepper Pike, Ohio);  Zeneng Wang (Shaker Heights, Ohio);  Bruce S. Levison (Twinsburg, Ohio)
ABSTRACT The present invention provides markers and methods for determining whether a subject, particularly a human subject, has or is at risk of developing, a disease such as cardiovascular disease, diabetes mellitus, insulin resistance, metabolic syndrome, NAFLD (Nonalcoholic Fatty Liver Disease) or NASH (Nonalcoholic Steatohepatitis) (e.g., within the ensuing year, two years, and/or three years). The present application also relates to the use of such markers and methods for monitoring the status of such diseases in a subject or the effects of therapeutic agents on subjects with such diseases.
FILED Monday, April 19, 2021
APPL NO 17/234229
ART UNIT 1678 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/43 (20130101)
A61K 31/496 (20130101)
A61K 31/4164 (20130101)
A61K 31/7036 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/18 (20130101)
C12Q 1/025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/88 (20130101) Original (OR) Class
G01N 30/7233 (20130101)
G01N 33/6893 (20130101)
G01N 2030/8813 (20130101)
G01N 2030/8822 (20130101)
G01N 2800/04 (20130101)
G01N 2800/32 (20130101)
G01N 2800/042 (20130101)
G01N 2800/044 (20130101)
G01N 2800/50 (20130101)
G01N 2800/52 (20130101)
G01N 2800/323 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835526 Chiu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute on Aging (NIA)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Washington (Seattle, Washington);  Clemson University Research Foundation (Clemson, South Carolina)
ASSIGNEE(S) University of Washington (Seattle, Washington);  Clemson University Research Foundation (Clemson, South Carolina)
INVENTOR(S) Daniel T. Chiu (Seattle, Washington);  Changfeng Wu (Changchun, China PRC);  Jason McNeill (Clemson, South Carolina);  Jiangbo Yu (Bothell, Washington)
ABSTRACT The present invention provides, among other aspects, functionalized chromophoric polymer dots comprising a hydrophobic core and a hydrophilic cap, and bioconjugates thereof. Also provided are improved methods for preparing functionalized chromophoric polymer dots. Methods for in vivo imaging and molecular labeling are also disclosed.
FILED Tuesday, February 15, 2022
APPL NO 17/672586
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/582 (20130101)
G01N 33/587 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835607 Stautner
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Ernst Wolfgang Stautner (Niskayuna, New York)
ABSTRACT The present disclosure relates to a cooling system that includes a superconducting unit and a reservoir configured to store liquid coolant to cool the superconducting unit. The cooling system also includes an auxiliary storage system that includes one or more storage tanks fluidly coupled to the reservoir. The auxiliary storage system is configured to provide additional coolant to the reservoir as well as receive and store coolant from the reservoir.
FILED Tuesday, July 14, 2020
APPL NO 16/928858
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases
F17C 7/04 (20130101)
F17C 2221/017 (20130101)
F17C 2227/0337 (20130101)
F17C 2270/0536 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/3856 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835609 Zu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) ZhongLiang Zu (Nashville, Tennessee)
ABSTRACT Imaging methods for assessing the macromolecular content, such as myelin, are of great interest for understanding brain tissue microstructure, and have shown potentials in diagnosing and prognosing demyelinating diseases. for example. Magnetization transfer (MT) is a MRI contrast mechanism that enables detection of macromolecules. Previously, the MT effect has been analyzed by a semi-quantitative method termed magnetization transfer ratio (MTR) or by a quantitative magnetization transfer (qMT) method. However, because MTR does not have enough sensitivity and specificity to myelin, and qMT takes a very long scan time, their translation into clinical scenarios has been limited. This disclosure describes a MT data analysis metric using double saturation pulse offsets and powers (dopMTR). Simulations and experiments using the systems and methods described in this disclosure show that the dopMTR yields much better sensitivity and specificity to MT effect than the conventional MTR, and requires much less scan time than the qMT.
FILED Monday, November 07, 2022
APPL NO 17/982190
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5605 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835611 Basser et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Peter J. Basser (Washington, District of Columbia);  Alexandru V. Avram (Gaithersburg, Maryland)
ABSTRACT Isotropic generalized diffusion tensor imaging methods and apparatus are configured to obtain signal attenuations using selected sets of applied magnetic field gradient directions whose averages produce mean apparent diffusion constants (mADCs) over a wide range of b-values, associated with higher order diffusion tensors (HOT). These sets are selected based on analytical descriptions of isotropic HOTs and the associated averaged signal attenuations are combined to produce mADCs, or probability density functions of intravoxel mADC distributions. Estimates of biologically-specific rotation-invariant parameters for quantifying tissue water mobilities or other tissue characteristics can be obtained such as Traces of HOTs associated with diffusion and mean t-kurtosis.
FILED Friday, April 06, 2018
APPL NO 16/603205
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/004 (20130101)
A61B 5/20 (20130101)
A61B 5/0042 (20130101)
A61B 5/0044 (20130101)
A61B 5/055 (20130101)
A61B 5/416 (20130101)
A61B 5/4029 (20130101)
A61B 5/4244 (20130101)
A61B 5/4255 (20130101)
A61B 5/4343 (20130101)
A61B 5/4381 (20130101)
A61B 5/4519 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/385 (20130101)
G01R 33/5608 (20130101)
G01R 33/56341 (20130101) Original (OR) Class
G01R 33/56509 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835706 Gopinath et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, A Body Corporate (Denver, Colorado)
INVENTOR(S) Juliet T. Gopinath (Boulder, Colorado);  Emily A. Gibson (Boulder, Colorado);  Victor M. Bright (Boulder, Colorado);  Richard Weir (Longmont, Colorado);  Diego Restrepo (Littleton, Colorado);  Baris Ozbay (Denver, Colorado)
ABSTRACT The present disclosure relates optical imaging devices and methods useful in biological and medical imaging applications. In one embodiment, an optical imaging device includes a flexible lightguide having a first end and a second end, the output of the source of pulsed infrared radiation being optically coupled to the first end of the flexible lightguide; a lens assembly attached to and optically coupled to the second end of the flexible lightguide, the lens assembly comprising a variable-focus lens element, the a variable-focus lens element having a tunable focal length; and a photodetector coupled to the flexible lightguide to detect radiation propagating from the second end toward the first end of the flexible lightguide. The optical imaging devices and methods can be used in both confocal and multi-photon techniques.
FILED Monday, April 20, 2020
APPL NO 16/853512
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 3/14 (20130101)
G02B 6/06 (20130101)
G02B 21/006 (20130101)
G02B 21/0032 (20130101)
G02B 21/0076 (20130101)
G02B 23/26 (20130101)
G02B 23/243 (20130101) Original (OR) Class
G02B 23/2446 (20130101)
G02B 23/2469 (20130101)
G02B 26/005 (20130101)

Pictorial Communication, e.g Television
H04N 23/56 (20230101)
H04N 23/555 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835707 Liang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Kaicheng Liang (Cambridge, Massachusetts);  James G. Fujimoto (Cambridge, Massachusetts);  Osman Oguz Ahsen (Cambridge, Massachusetts);  Michael Gene Giacomelli (Cambridge, Massachusetts);  Hsiang-Chieh Lee (Cambridge, Massachusetts);  Zhao Wang (Cambridge, Massachusetts)
ABSTRACT The present disclosure pertains to an apparatus and methods of an imaging device for obtaining images from the walls of luminal organs or a surgical cavity. The device is capable of passage through luminal organs or introduction into surgical cavities, and obtains images by rapidly scanning a focused light beam on the tissue to be imaged and receiving light from the tissue. The device comprises at least one mechanism for projecting a 2-dimensional (2-D) optical pattern, such as a 2-D scanner (508) or a 2-D optical array forming a closed loop scan pattern (506). The device comprises at least one other beam scanning mechanism, such as a rotary or angular scanner (510) such that cycloid scan pattern is formed on the surface to be scanned, and also has embodiments of focusing optics at different regimes of numerical aperture. The disclosure also describes methods for accurate image reconstruction with embodiments of hardware control and post-acquisition processing.
FILED Thursday, May 03, 2018
APPL NO 16/496371
ART UNIT 2425 — Cable and Television
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/00165 (20130101)
A61B 1/00172 (20130101)
A61B 1/00188 (20130101)
A61B 5/0066 (20130101)
A61B 5/0068 (20130101)

Optical Elements, Systems, or Apparatus
G02B 23/26 (20130101) Original (OR) Class
G02B 26/103 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835733 Ruan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Haowen Ruan (Pasadena, California);  Changhuei Yang (South Pasadena, California);  Jian Xu (Pasadena, California)
ABSTRACT Optical wavefront shaping has been the standard technique to control light through scattering media. Implicit in this dominance is the assumption that knowledge of the optical phase is a necessity for optical control through scattering media. In this paper, we challenge this assumption by reporting on an intensity-only approach for light control through (or reflected from) a disordered scattering medium—optical-channel-based intensity streaming (OCIS). Instead of actively tuning the interference between the optical paths via wavefront shaping, OCIS can control light and transmit information through or from scattering media with linear intensity operation, which not only simplifies and speeds up the system but also enables new applications. We experimentally created focus patterns through scattering media in a sub-millisecond timescale with a phase-manipulation-free setup. We also demonstrate that, unlike wavefront shaping, OCIS can readily generate distinct energy null points through scattering media. Finally, we demonstrate that OCIS enables a scattering medium mediated secure optical communication application.
FILED Wednesday, September 16, 2020
APPL NO 17/023070
ART UNIT 2636 — Optical Communications
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 26/105 (20130101)
G02B 26/0833 (20130101)
G02B 27/48 (20130101) Original (OR) Class

Transmission
H04B 10/61 (20130101)
H04B 10/504 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835770 Song et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
APPLICANT(S) ChiSquare Bioimaging LLC (Brookline, Massachusetts)
ASSIGNEE(S) ChiSquare Bioimaging LLC (Framingham, Massachusetts)
INVENTOR(S) Loling Song (Chestnut Hill, Massachusetts);  Hendrik van Gorsel (Chestnut Hill, Massachusetts)
ABSTRACT An automated fiber optic rotary joint (FORJ) dynamically measures, using an angle encoder, twists in an optical fiber cable caused by movements of a mouse or other animal and automatically unwinds the optical fiber cable(s) by engaging a motor. To optimize its efficiency, the unwinding process is activated automatically only when the angle encoder reaches a predetermined threshold. In some embodiments, the optical fiber is unwound in increments of 360°. Various embodiments allow simultaneous transfer of optical signals through independent channels to and from multiple sites of a freely moving animal through a rotating interface and with minimal mechanical impact on the natural behavior of the animal. The design principle leads to a minimal variation of light transmission over rotation suitable for life science applications. A single channel FORJ device can be readily expanded to a two-, three- or more-channel device.
FILED Sunday, January 24, 2021
APPL NO 17/156600
ART UNIT 2874 — Optics
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 29/005 (20130101)

Diagnosis; Surgery; Identification
A61B 5/6868 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/0622 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/3604 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836291 Aceros et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Juan Aceros (St. Johns, Florida);  Matthew Cantwell (Orange Park, Florida);  John Prisco (Holly Springs, Georgia)
ASSIGNEE(S) University of North Florida Board of Trustees (Jacksonville, Florida)
INVENTOR(S) Juan Aceros (St. Johns, Florida);  Matthew Cantwell (Orange Park, Florida);  John Prisco (Holly Springs, Georgia)
ABSTRACT Described herein relates to an apparatus and method for developmental and/or rehabilitative sensory substitution to augment at least one low-functioning and/or non-functioning senses in at least one user. The apparatus may include an input module that may allow the user to perform various tasks designed to enhance development of or sensory recognition by the user. The apparatus may be capable of multiple different proportional controls and of being used across ages, sizes, and developmental stages. For example, the apparatus may include at least one joystick, button, lever, and accelerometer, such that a sensory feedback response (e.g., haptic/tactile, visual, and/or auditory) may be provided to the user across a plurality of exercises. Additionally, the apparatus may provide a new standard of care for individuals with special needs and/or those recovering from a traumatic physical and/or mental injury, regardless of ability level and age.
FILED Wednesday, September 07, 2022
APPL NO 17/939421
ART UNIT 2627 — Selective Visual Display Systems
CURRENT CPC
Electric Digital Data Processing
G06F 3/011 (20130101)
G06F 3/016 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836611 Yu et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Hong Yu (Shrewsbury, Massachusetts);  Tsendsuren Munkhdalai (Worcester, Massachusetts)
ABSTRACT Classification of an input task data set by meta level continual learning includes analyzing first and second training data sets in a task space to generate first and second meta weights and a slow weight value, and comparing an input task data set to the slow weight to generate a fast weight. The first and second meta weights are parameterized with the fast weight value to update the slow weight value, whereby a value is associated with the input task data set, thereby classifying the input task data set by meta level continual learning.
FILED Tuesday, July 24, 2018
APPL NO 16/044108
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 3/08 (20130101) Original (OR) Class
G06N 3/044 (20230101)
G06N 3/045 (20230101)
G06N 3/047 (20230101)
G06N 3/048 (20230101)
G06N 3/063 (20130101)
G06N 3/084 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836918 Wick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) CAMERAD TECHNOLOGIES (Decatur, Georgia)
ASSIGNEE(S) CAMERAD TECHNOLOGIES (Decatur, Georgia)
INVENTOR(S) Carson A. Wick (Decatur, Georgia);  Srini Tridandapani (Decatur, Georgia)
ABSTRACT A method for identifying a misidentified study can utilize a set of photographs captured at substantially the same time as a corresponding set of medical images. The method can include determining similarities between the photographs through machine learning models and determining that a misidentified study exists when the similarity between the photographs fails to satisfy a threshold similarity.
FILED Friday, September 09, 2022
APPL NO 17/942026
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836998 Chennubhotla et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Srinivas C. Chennubhotla (Pittsburgh, Pennsylvania);  Douglass L. Taylor (Pittsburgh, Pennsylvania);  Shikhar Uttam Fnu (Pittsburgh, Pennsylvania)
ABSTRACT A method of predicting cancer recurrence risk for an individual includes receiving patient spatial multi-parameter cellular and sub-cellular imaging data for a tumor of the individual, and analyzing the patient spatial multi-parameter cellular and sub-cellular imaging data using a prognostic model for predicting cancer recurrence risk to determine a predicted cancer recurrence risk for the individual, wherein the joint prognostic model is based on spatial correlation statistics among features derived for a plurality of intra-tumor spatial domains from spatial multi-parameter cellular and sub-cellular imaging data obtained from a plurality of cancer patients.
FILED Thursday, May 23, 2019
APPL NO 17/056080
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 18/211 (20230101)
G06F 18/217 (20230101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)

Image or Video Recognition or Understanding
G06V 10/26 (20220101)
G06V 10/50 (20220101)
G06V 10/771 (20220101)
G06V 10/776 (20220101)
G06V 20/698 (20220101) Original (OR) Class
G06V 2201/03 (20220101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11832826 Williams et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Timothy K Williams (Davis, California);  Lucas Paul Neff (Davis, California)
ABSTRACT Endovascular variable aortic control catheters (EVACC) are provided that are adapted to augment upstream blood pressure and regulate downstream blood flow for patients in shock. The EVACC devices provide improved treatment for truncal wounds, which may be used for example on a battlefield, thereby increasing survivability of injured soldiers. The devices are a catheter-based system having a proximal hand piece for controlled deployment of the device through a delivery sheath. A collapsible, wire framework supports an expandable and collapsible occlusion barrier. The wire basket and occlusion barrier expand to fit within the lumen of the aorta. Various movable elements are used to adjust an adjustable passageway to regulate controlled anterograde blood flow.
FILED Tuesday, April 02, 2019
APPL NO 16/373323
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/12109 (20130101) Original (OR) Class
A61B 17/12122 (20130101)
A61B 17/12131 (20130101)
A61B 17/12168 (20130101)
A61B 17/12172 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 60/13 (20210101)
A61M 60/50 (20210101)
A61M 60/139 (20210101)
A61M 60/295 (20210101)
A61M 60/833 (20210101)
A61M 60/843 (20210101)
A61M 2205/3334 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11832833 Donaldson et al.
FUNDED BY
Department of Defense (DOD)
Defense Health Agency (DHA)
APPLICANT(S) Critical Innovations LLC (Inglewood, California)
ASSIGNEE(S) Critical Innovations, LLC (Lawndale, California)
INVENTOR(S) Ross I. Donaldson (Inglewood, California);  Oliver Buchanan (Inglewood, California);  Muhammed Hamdan (Inglewood, California);  Tim Fisher (Inglewood, California);  John Cambridge (Inglewood, California);  Jonathan Armstrong (Inglewood, California)
ABSTRACT An improved method and device are provided for forming and/or maintaining a percutaneous access pathway. The device generally comprises an access pathway. The provided assembly substantially reduces the possibility of injury while accessing and/or re-accessing a body space.
FILED Monday, October 05, 2020
APPL NO 16/948885
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/00234 (20130101)
A61B 17/1615 (20130101)
A61B 17/1695 (20130101) Original (OR) Class
A61B 17/3423 (20130101)
A61B 2017/00238 (20130101)
A61B 2017/3425 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11832845 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Richard Rox Anderson (Boston, Massachusetts);  William A. Farinelli (Danvers, Massachusetts);  Walfre Franco (Worcester, Massachusetts);  Joshua Tam (Charlestown, Massachusetts);  Fernanda H. Sakamoto (Boston, Massachusetts);  Apostolos G. Doukas (Belmont, Massachusetts);  Martin Purschke (Dorchester, Massachusetts);  Min Yao (Boston, Massachusetts)
ABSTRACT Exemplary embodiments of apparatus and method for obtaining one or more portions of biological tissue (“micrografts”) to form grafts are provided. For example, a hollow tube can be inserted into tissue at a donor site, and a pin provided within the tube can facilitate controlled removal of the micrograft from the tube. Micrografts can be harvested and directly implanted into an overlying biocompatible matrix through coordinated motion of the tube and pin. A needle can be provided around the tube to facilitate a direct implantation of a micrograft into a remote recipient site or matrix. The exemplary apparatus can include a plurality of such tubes and pins for simultaneous harvesting and/or implanting of a plurality of micrografts. The harvested micrografts can have a small dimension, e.g., less than about 1 mm, which can promote healing of the donor site and/or viability of the harvested tissue.
FILED Monday, July 06, 2020
APPL NO 16/921744
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/0233 (20130101)
A61B 17/322 (20130101) Original (OR) Class
A61B 17/3205 (20130101)
A61B 17/32053 (20130101)
A61B 2017/00747 (20130101)
A61B 2017/00752 (20130101)
A61B 2017/00969 (20130101)
A61B 2017/3225 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11832871 Farritor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Telemedicine and Advanced Technology Research Center (TATRC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Office of The Director (OD)
Experimental Program to Stimulate Competitive Research (EPS)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Shane Farritor (Lincoln, Nebraska);  Tom Frederick (Gretna, Nebraska);  Joe Bartels (Pittsburgh, Pennsylvania)
ABSTRACT The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices, and more specifically including end effectors that can be incorporated into such devices. Certain end effector embodiments include various vessel cautery devices that have rotational movement as well as cautery and cutting functions while maintaining a relatively compact structure. Other end effector embodiments include various end effector devices that have more than one end effector.
FILED Monday, June 21, 2021
APPL NO 17/352817
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/1445 (20130101) Original (OR) Class
A61B 34/30 (20160201)
A61B 2018/0063 (20130101)
A61B 2018/00345 (20130101)
A61B 2018/00595 (20130101)
A61B 2018/1455 (20130101)
A61B 2034/301 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11832953 Shanechi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Maryam M. Shanechi (Los Angeles, California);  Omid Ghasem Sani (Los Angeles, California)
ABSTRACT A method for preferential system identification (PSID) for modeling neural dynamics of a brain includes extracting behaviorally relevant latent brain states via a projection of future behavior onto past neural activity. The method further includes identifying, based on the extracted latent brain states, model parameters for a linear state space dynamic model of neural activity. An extension of PSID includes accounting for an effect of external inputs to the brain by using oblique projections along the external inputs instead of orthogonal projections. PSID may be extended to apply to any primary signals and secondary signals in place of the neural activity and the behavior. In some embodiments, the extracting and the identifying may be performed using a numerical optimization of recurrent neural networks (RNN) instead of the projection.
FILED Tuesday, October 13, 2020
APPL NO 17/069510
ART UNIT 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/725 (20130101)
A61B 5/4064 (20130101) Original (OR) Class
A61B 5/7264 (20130101)
A61B 5/7275 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833159 McCall et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) ReveraGen BioPharma, Inc. (Rockville, Maryland)
ASSIGNEE(S) ReveraGen BioPharma, Inc. (Rockville, Maryland)
INVENTOR(S) John M. McCall (Boca Grande, Florida);  Eric Hoffman (Rockville, Maryland);  Kanneboyina Nagaraju (Highland, Maryland)
ABSTRACT The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy.
FILED Wednesday, October 28, 2020
APPL NO 17/082521
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/57 (20130101)
A61K 31/573 (20130101) Original (OR) Class
A61K 31/575 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/04 (20180101)
A61P 1/16 (20180101)
A61P 3/00 (20180101)

Steroids
C07J 5/0038 (20130101)
C07J 5/0053 (20130101)
C07J 5/0076 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833272 Omenetto et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) Fiorenzo G. Omenetto (Lexington, Massachusetts);  Matthew B. Applegate (Somerville, Massachusetts);  David L. Kaplan (Concord, Massachusetts)
ABSTRACT The present disclosure provides transparent, elastic silk hydrogels for applications, including corneal reshaping to restore visual acuity and photolithography. The present disclosure also provides methods of photocrosslinking silk fibroin protein using riboflavin as a photoinitiator and exposing such riboflavin doped silk fibroin to light resulting in the formation of a transparent, elastic hydrogel.
FILED Friday, December 16, 2016
APPL NO 16/063479
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/48 (20130101)
A61L 27/52 (20130101) Original (OR) Class
A61L 2400/06 (20130101)
A61L 2430/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833346 Park et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Hongkun Park (Cambridge, Massachusetts);  Donhee Ham (Cambridge, Massachusetts);  Jeffrey T. Abbott (Cambridge, Massachusetts);  Ling Qin (Cambridge, Massachusetts);  Marsela Jorgolli (Cambridge, Massachusetts);  Tianyang Ye (Cambridge, Massachusetts)
ABSTRACT The present invention generally relates to nanowires. In one aspect, the present invention is generally directed to systems and methods of individually addressing nanowires on a surface, e.g., that are substantially upstanding or vertically-oriented with respect to the surface. In some cases, one or more nanowires may be individually addressed using various integrated circuit (“IC”) technologies, such as CMOS. For example, the nanowires may form an array on top of an active CMOs integrated circuit.
FILED Friday, January 08, 2021
APPL NO 17/144387
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/05 (20130101)
A61N 1/06 (20130101)
A61N 1/0531 (20130101) Original (OR) Class
A61N 1/0536 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/48 (20130101)
H01L 23/49 (20130101)
H01L 29/0676 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/14 (20130101)
H01L 2924/10253 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833353 Wilder et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) VERITAS IP, LLC (Salt Lake City, Utah)
ASSIGNEE(S) Veritas IP, LLC (Salt Lake City, Utah)
INVENTOR(S) Andrew Miller Wilder (Salt Lake City, Utah);  Scott Darold Hiatt (South Jordan, Utah);  Steven John Barrus (North Salt Lake, Utah);  Cliff C. Nixon (Phoenix, Arizona)
ABSTRACT Various embodiments of an interface control subsystem may be used between an electrode terminal and a recording terminal of a neurostimulation and neurorecording system. The interface control subsystem may operate in three modes. In a disable mode, a first transistor and a second transistor disposed between the electrode terminal and the recording terminal may operate in a cutoff region and generate a high impedance. In an active mode, the first transistor and the second transistor may operate in a saturation region and generate a low impedance. In a stimulation mode, the first transistor and the second transistor operate in a triode region and generate an impedance between the high impedance of the disable mode and the low impedance of the active mode. The interface control subsystem may further limit voltage at the recording terminal in response to a detected overvoltage condition.
FILED Friday, May 07, 2021
APPL NO 17/315160
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/7217 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/025 (20130101)
A61N 1/36128 (20130101) Original (OR) Class
A61N 2001/083 (20130101)

Electric Digital Data Processing
G06F 3/015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833373 Letter
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Benjamin E. Letter (Philadelphia, Pennsylvania)
ABSTRACT An articulated oxygen candle furnace basket is provided with a hinged assembly allowing opening and closing of the basket for simple insertion of fresh oxygen candles, and efficient removal of exhausted candles.
FILED Wednesday, September 30, 2020
APPL NO 16/948750
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Devices, Apparatus or Methods for Life-saving
A62B 21/00 (20130101) Original (OR) Class

Non-metallic Elements; Compounds Thereof;
C01B 13/0296 (20130101)

Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for
F21V 35/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833487 Cooks et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Michael Stanley Wleklinski (Indianapolis, Indiana);  David Logsdon (West Lafayette, Indiana)
ABSTRACT The invention generally relates to systems and methods for increasing reaction yield. In certain embodiments, the invention provides systems for increasing a yield of a chemical reaction that include a pneumatic sprayer configured to generate a liquid spray discharge from a solvent. The solvent includes a plurality of molecules, a portion of which react with each other within the liquid spray discharge to form a reaction product. The system also includes a collector positioned to receive the liquid spray discharge including the unreacted molecules and the reaction product. The system also includes a recirculation loop connected from the collector to the pneumatic sprayer in order to allow the unreacted molecules and the reaction product to be recycled through the pneumatic sprayer, thereby allowing a plurality of the unreacted molecules to react with each other as the unreacted molecules cycle again through the system.
FILED Monday, May 17, 2021
APPL NO 17/322339
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Separation
B01D 5/0069 (20130101)
B01D 19/0031 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 4/002 (20130101)
B01J 14/00 (20130101)
B01J 19/26 (20130101)
B01J 19/087 (20130101)
B01J 19/2465 (20130101) Original (OR) Class
B01J 2219/00087 (20130101)
B01J 2219/00099 (20130101)
B01J 2219/0803 (20130101)
B01J 2219/0884 (20130101)

Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 5/03 (20130101)
B05B 5/025 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833875 Morgan et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Prostate Cancer Research Program (USAMRMCPCRP)
APPLICANT(S) PRATT and MILLER ENGINEERING AND FABRICATION, INC. (New Hudson, Michigan)
ASSIGNEE(S) PRATT and MILLER ENGINEERING AND FABRICATION, LLC (New Hudson, Michigan)
INVENTOR(S) Christopher M. Morgan (Ann Arbor, Michigan);  John Edward Ustick (Bloomfield Hills, Michigan);  Guido Francesco Ritelli (Farmington Hills, Michigan)
ABSTRACT A ground plane detection system for a motor vehicle and a motor vehicle with enhanced maneuverability characteristics of a type including a frame structure, a pair of front road engaging wheels, a pair of rear road engaging wheels. The detection system includes, a body controller configured for determining a ground plane including receiving at least one of a GPS signal and an inertial navigation system signal. The body controller is further configured for providing a roll and a pitch signal with respect to the ground plane; and the body controller combining the signals with inputs from one or more sensors detecting displacement of the front and rear road engaging wheels. The body controller is also configured to determine a terrain plane reference to the ground plane, and providing control signals to cause the vehicle to undertake an earth level orientation mode or a terrain following orientation mode.
FILED Friday, April 19, 2019
APPL NO 17/048971
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Vehicle Suspension Arrangements
B60G 7/001 (20130101)
B60G 17/0165 (20130101) Original (OR) Class
B60G 2400/82 (20130101)
B60G 2400/0511 (20130101)
B60G 2400/0512 (20130101)
B60G 2401/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834163 Patterson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) David Patterson (Hudson, New Hampshire);  Mark Silver (Bedford, Massachusetts)
ABSTRACT An aerial vehicle with a plurality of selectively collapsible arms capable of transitioning between an extended state and a contracted state is described. In the extended position, the distance between the main body of the vehicle and the rotor associated with each arm is maximized. In the contracted state, the distance between the main body of the vehicle and the rotor associated with each arm is minimized. In certain embodiments, each of the arms may include one or more tape springs that are biased to selectively move the associated one or more rotors of each arm between the retracted and extended states.
FILED Tuesday, March 09, 2021
APPL NO 17/196102
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/33 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834179 Albrecht et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Nicholas H. Albrecht (Ridgecrest, California);  Vincent R. Schuetz (Ridgecrest, California);  Pavel K. Rybakov (Ridgecrest, California);  Chase A. York (Ridgecrest, California);  Scott D Slaughter (Ridgecrest, California);  Derek A. Hamel (Ridgecrest, California)
ABSTRACT Embodiments are directed to releasing smaller unmanned aerial vehicles from larger unmanned aerial vehicles. Apparatus and system embodiments are disclosed for physically retaining and ejecting the smaller unmanned aerial vehicles, including the communication networks associated with the command and control of both the smaller unmanned aerial vehicles and the larger unmanned aerial vehicles.
FILED Tuesday, May 04, 2021
APPL NO 17/307657
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 1/02 (20130101) Original (OR) Class
B64D 5/00 (20130101)

Unmanned aerial vehicles [UAV]; equipment therefor
B64U 80/82 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834383 Reaves et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Lynntech, Inc. (College Station, Texas)
ASSIGNEE(S) Lynntech, Inc. (College Station, Texas)
INVENTOR(S) Kelley Reaves (College Station, Texas);  Jared Mike (College Station, Texas);  Richard Sanchez, Jr. (Bryan, Texas);  Billy McCulloch (Bryan, Texas);  Anthony Giletto (College Station, Texas);  David M. Battaglia (College Station, Texas);  Kacey G. Ortiz (Auburn, Alabama)
ABSTRACT The present invention comprises formulations and method for additive manufacturing comprising: a pot-stable photo-curable polymer; one or more fillers; and one or more additives, wherein the formulation cures into a polymer in six hours or less upon exposure to light. In certain examples, the additive manufacturing is a moldless method of additive manufacturing by preparing a formulation comprising: a pot-stable photo-curable polymer, one or more fillers, and one or more additives, and exposing the formulation to light in an amount that substantially cures the polymer in 6 hours or less.
FILED Wednesday, November 27, 2019
APPL NO 16/698562
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 21/0025 (20130101)
C06B 21/0033 (20130101)
C06B 25/00 (20130101)
C06B 25/10 (20130101)
C06B 25/34 (20130101)
C06B 29/22 (20130101)
C06B 31/28 (20130101)
C06B 45/10 (20130101) Original (OR) Class
C06B 45/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834416 Goodson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Board of Trustees of Southern Illinois University (Carbondale, Illinois);  Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Board of Trustees of Southern Illinois University (Carbondale, Illinois);  Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Boyd M. Goodson (Carbondale, Illinois);  Eduard Y. Chekmenev (Troy, Michigan);  Bryce E. Kidd (Carbondale, Illinois);  Jamil A. Mashni (Carbondale, Illinois);  Miranda Limbach (Creal Springs, Illinois);  Yuqing Hou (Carbondale, Illinois);  Fan Shi (Houston, Texas)
ABSTRACT The present disclosure is directed to a cleavable agent for enhanced magnetic resonance generally corresponding to the formula Y-L-R, wherein Y represents a catalyst-binding moiety having at least one isotopically labeled heteroatom, L represents a cleavable bond, and R represents a hyperpolarized payload having at least one isotopically labeled carbon. Also disclosed herein is a method of cleaving the cleavable agent for enhanced magnetic resonance.
FILED Wednesday, November 27, 2019
APPL NO 16/698332
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/12 (20130101)
B01J 2531/827 (20130101)

Heterocyclic Compounds
C07D 213/46 (20130101)
C07D 213/63 (20130101)
C07D 233/60 (20130101) Original (OR) Class
C07D 241/12 (20130101)
C07D 401/06 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/6506 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/46 (20130101)
G01R 33/282 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834509 Qin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Haiying Qin (Potomac, Maryland);  Terry J. Fry (Bethesda, Maryland)
ABSTRACT The invention provides a chimeric antigen receptor (CAR) comprising an antigen binding domain specific for TSLPR, a transmembrane domain, and an intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of a proliferative disorder, e.g., cancer, in a mammal and methods of treating or preventing a proliferative disorder, e.g., cancer, in a mammal are also disclosed.
FILED Tuesday, April 28, 2020
APPL NO 16/860216
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/7051 (20130101)
C07K 14/7151 (20130101)
C07K 14/70517 (20130101)
C07K 16/2803 (20130101)
C07K 16/2866 (20130101) Original (OR) Class
C07K 16/3061 (20130101)
C07K 2317/524 (20130101)
C07K 2317/526 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2319/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834512 Deb
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Arjun Deb (Los Angeles, California)
ABSTRACT In certain aspects, provided herein are inhibitory anti-ENPP1 antibodies and antigen binding fragments thereof. In some aspects, provided herein are methods of treating myocardial infarction using the antibodies provided herein. In certain aspects, provided herein are nucleic acid molecules encoding the antibodies provided herein, host cells comprising such nucleic acids, and methods of making the antibodies provided herein using such host cells. In some aspects, also provided herein are pharmaceutical compositions comprising the antibodies provided herein.
FILED Monday, May 03, 2021
APPL NO 17/306544
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Peptides
C07K 16/40 (20130101)
C07K 16/2896 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/52 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834651 Funkner et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) CureVac Manufacturing GmbH (Tübingen, Germany)
ASSIGNEE(S) CureVac Manufacturing GmbH (Tübingen, Germany)
INVENTOR(S) Andreas Funkner (Tübingen, Germany);  Stefanie Dorner (Tübingen, Germany);  Stefanie Sewing (Tübingen, Germany);  Johannes Kamm (Tübingen, Germany);  Norbert Broghammer (Tübingen, Germany);  Thomas Ketterer (Gomaringen, Germany);  Thorsten Mutzke (Reutlingen, Germany)
ABSTRACT The present invention relates to method for producing and purifying RNA comprising the steps of providing DNA encoding the RNA; transcription of the DNA into RNA; and conditioning and/or purifying of the solution comprising transcribed RNA by one or more steps of tangential flow filtration (TFF).
FILED Tuesday, May 16, 2023
APPL NO 18/198258
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Separation
B01D 61/145 (20130101)
B01D 71/12 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1017 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/02 (20130101)
G01N 2030/027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834875 McIntire et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) John P. McIntire (Dayton, Ohio);  Matthew Srnoyachki (Beavercreek, Ohio)
ABSTRACT The emergency egress apparatus includes a protuberance mated to a first portion of the door barricade and a keeper mated to a second portion of the door barricade. A retainer is selectively disposed between one of two positions. A first position defines the placement of the retainer that establishes an interference fit between the protuberance and the keeper. A second position defines the placement of the retainer such that it is not in contact with the protuberance or the keeper. The first position secures the first portion of the door barricaded with respect to the second portion of the door barricade, and the second position decouples the first portion of the door barricade with respect to the second portion of the door barricade.
FILED Wednesday, June 06, 2018
APPL NO 16/001372
ART UNIT 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Bolts or Fastening Devices for Wings, Specially for Doors or Windows
E05C 17/08 (20130101)
E05C 17/54 (20130101)
E05C 19/184 (20130101) Original (OR) Class
E05C 19/188 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834959 Neely et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Jared Neely (Troy, Ohio);  James Joo (Centerville, Ohio);  Russel Topp (Dayton, Ohio)
ABSTRACT A morphing airfoil includes a dynamic flexible skin system that is capable of carrying high level aerodynamic (or fluid) pressure loads over a structural surface. The structural surface can morph and bend in response to control inputs to change a lift force without separate movable control surfaces. A plurality of standoff mounts is attached to an inner surface of anisotropic skin. The standoff mounts include through apertures for receiving a flexible stringer. The anisotropic skin is attached to underlying structure through the flexible stringers. The flexible stringers interface with actuated position control ribs and passive compliant support ribs. A control system causes the underlying support structure to move to a desired location which in turn causes the skin to bend and/or flex without exceeding a stress threshold and thus vary the lift and drag distributions along a span of the airfoil without separate control surfaces.
FILED Wednesday, October 12, 2022
APPL NO 17/964118
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 3/26 (20130101)
B64C 3/48 (20130101)
B64C 2003/445 (20130101)

Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/141 (20130101)
F01D 5/147 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2250/90 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835064 Heeter et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana);  Rolls-Royce Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana);  Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S) Robert W. Heeter (Indianapolis, Indiana);  Daniel E. Molnar, Jr. (Indianapolis, Indiana);  Kathryn A. Sontag (Indianapolis, Indiana);  Michael G. Meyer (Indianapolis, Indiana)
ABSTRACT A gas turbine engine comprises an engine core and an electric fan array. The engine core includes a compressor, a combustor, and a turbine. The compressor compresses and delivers air to the combustor. The combustor mixes fuel with the compressed air received from the compressor and ignites the fuel. The hot, high-pressure products of the combustion reaction in the combustor are directed into the turbine to cause the turbine to rotate about an axis and drive the compressor. The electric fan array may include at least two non-concentric fans having parallel shafts.
FILED Tuesday, December 27, 2022
APPL NO 18/089029
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/04 (20130101)
F02C 6/00 (20130101)
F02C 9/16 (20130101)

Non-positive-displacement Pumps
F04D 25/06 (20130101)
F04D 27/004 (20130101)
F04D 29/661 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835156 Di Carlo et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Arlington, Virginia)
INVENTOR(S) Tony Di Carlo (Long Beach, California);  Brian T. Vaniman (Fountain Valley, California);  John P. Leuer (Newport Beach, California)
ABSTRACT A method of fabricating a conduit comprises simultaneously corrugating three plies to form a bellows. The method also comprises simultaneously trimming a corrugated inboard ply and a first corrugated outboard ply of the bellows. The method further comprises locating a weld-through ring and a second weld-through ring between the corrugated inboard ply and the first corrugated outboard ply. The method additionally comprises forming a port and a second port through the weld-through ring and the second weld-through ring, respectively. The method also comprises communicatively coupling a sensor and a second sensor with an interstitial space, interposed between the corrugated inboard play and the first corrugated outboard ply, via the port and the second port, respectively.
FILED Thursday, August 13, 2020
APPL NO 16/992437
ART UNIT 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material
B21C 37/154 (20130101)

Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal
B21D 15/06 (20130101)
B21D 51/12 (20130101)

Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 5/022 (20130101) Original (OR) Class
F16L 27/111 (20130101)
F16L 2201/30 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 3/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835312 Hoffman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Brian Hoffman (Bloomington, Indiana);  Alex Smith (Long Valley, New Jersey);  Michael Colonnello (Mine Hill, New Jersey);  Eric Binter (Sussex, New Jersey)
ABSTRACT A remote weapon station (RWS) system for an unmanned ground vehicle (UGV) includes a dedicated weapon, multi-axis gimbal and ammunition handling capabilities with all operations functioning remotely and wirelessly. The RWS system is a gas powered, or self-powered, belt fed, rotating bolt lock weapon. In addition, the RWS is man-portable and air-droppable as the major subsystems may be latched together in the field without tooling or needing to make electrical connections.
FILED Friday, January 22, 2021
APPL NO 17/155457
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 7/06 (20130101)
F41A 9/34 (20130101)
F41A 9/37 (20130101)
F41A 19/08 (20130101) Original (OR) Class
F41A 19/12 (20130101)
F41A 19/58 (20130101)
F41A 25/00 (20130101)
F41A 25/14 (20130101)
F41A 27/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835323 Gupta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Washington State University (Pullman, Washington)
ASSIGNEE(S) Washington State University (Pullman, Washington)
INVENTOR(S) Yogendra M. Gupta (Spokane, Washington);  Atakan Peker (Spokane, Washington)
ABSTRACT Munitions structures comprising one or more high strength reactive alloys, in particular reactive bulk metallic glasses, have significant amounts of inherent chemical energy. This energy may be discharged by subjection of the munitions structure to rapid impulsive loading and fragmentation in the presence of oxygen and/or nitrogen. A munitions structure can be configured in both large and small penetrators, e.g. warheads and bullets, with increased lethality. The lethality of these munitions structures is augmented by means of rapidly and simultaneously imparting both mechanical energy (kinetic energy through impact and fragmentation) and chemical energy (blast and/or fireball) to a target. A high-strength reactive alloy can substitute at least in part one or both of explosives and inert structural materials in conventional munitions systems to improve performance and reduce parasitic weight of structural casing.
FILED Friday, March 04, 2022
APPL NO 17/687387
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Alloys
C22C 1/02 (20130101)
C22C 45/10 (20130101)

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 12/74 (20130101)
F42B 12/207 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835393 Yang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Lan Yang (St. Louis, Missouri);  Fang-Jie Shu (St. Louis, Missouri);  Xuefeng Jiang (St. Louis, Missouri);  Guangming Zhao (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Lan Yang (St. Louis, Missouri);  Fang-Jie Shu (St. Louis, Missouri);  Xuefeng Jiang (St. Louis, Missouri);  Guangming Zhao (St. Louis, Missouri)
ABSTRACT A microprobe is provided that includes a microsphere optical resonator operatively coupled to a nanoscatterer. The microsphere optical resonator includes a back surface and a front surface opposite the front surface. The front surface is configured to receive a focused laser beam, and the nanoscatterer is positioned adjacent to the back surface.
FILED Tuesday, December 11, 2018
APPL NO 16/216995
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Compositions of Macromolecular Compounds
C08L 25/06 (20130101)

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 11/00 (20130101)
G01K 11/26 (20130101)
G01K 11/32 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 1/04 (20130101)
G02B 1/04 (20130101)
G02B 6/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835404 Slater et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States Government of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) William H Slater (New Bedford, Massachusetts);  Brian K Amaral (Newport, Rhode Island);  Michael R Williams (West Kingston, Rhode Island);  Robert F Cutler, III (Tiverton, Rhode Island);  Kimberly M Cipolla (Portsmouth, Rhode Island)
ABSTRACT A tension sensor includes a planar tab having a first and second side, first and second end sections and an aperture through each of the end sections. A first strain gage is attached to the first side of the tab. The first strain gage has a tension grid aligned to a longitudinal axis of the tab and a cross-tension grid perpendicular to the tension grid. A second strain gage is attached to the second side of the tab. The second strain gage has a tension grid aligned to the longitudinal axis of the tab and a cross-tension grid perpendicular to the tension grid. The first strain gage and second strain gage are wired in a Wheatstone bridge in which the tension grid and the cross-tension grid of the first strain gage form one side and the tension grid and the cross-tension grid of the second strain gage form another side.
FILED Thursday, September 16, 2021
APPL NO 17/476519
ART UNIT 2833 — Electrical Circuits and Systems
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/2212 (20130101) Original (OR) Class
G01L 1/2287 (20130101)
G01L 5/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835444 Lever et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) United States of America as Represented by The Secretary of The Army (Alexandria, Virginia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia)
INVENTOR(S) James H Lever (Lebanon, New Hampshire);  Susan Taylor (Lebanon, New Hampshire);  Garrett R Hoch (Lebanon, New Hampshire);  Emily Asenath-Smith (Norwich, Vermont)
ABSTRACT In one embodiment, a tribometer comprises: an infrared (IR) transparent and optically transparent disk coupled to a platform, the disk having an observation side disk surface on an observation side of the disk and a contact side disk surface on a contact side of the disk; a motor coupled to the disk to rotate the disk around a rotational axis of the disk; a pivot support coupled to the platform; a pivoting member connected to the pivot support to pivot along a pivot plane; a sample holder configured to hold a sample and be coupled with the pivoting member to place the sample in contact with the contact side disk surface of the disk; and an IR camera and an optical microscope disposed on the observation side of the disk to observe the sample in sliding contact with the contact side disk surface of the disk driven in rotation.
FILED Wednesday, September 30, 2020
APPL NO 17/037703
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 19/02 (20130101) Original (OR) Class
G01N 19/08 (20130101)
G01N 21/01 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835545 McLeod et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Alexander Swinton McLeod (New York, New York);  Lin Xiong (Bronx, New York);  Shuai Zhang (New York, New York);  Dimitri N. Basov (New York, New York)
ABSTRACT An exemplary apparatus can provide radiation to a sample(s), which can include, for example, a radiation source arrangement configured to provide radiation, a beam splitter configured to split the radiation into (i) a first radiation, and (ii) a second radiation. An optical element can also be provided which, in operation, can, e.g., (a) receive the first radiation and the second radiation, (b) reflect the first radiation as a reference radiation, (c) provide the second radiation as illumination for the sample(s), (d) receive a resultant radiation from the sample(s) that can be based on the illumination from the second radiation, and (e) provide the reference radiation and the resultant radiation to be detected and used for interferometric imaging or spectroscopy.
FILED Thursday, January 14, 2021
APPL NO 17/149236
ART UNIT 2881 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 20/02 (20130101) Original (OR) Class
G01Q 30/18 (20130101)
G01Q 60/24 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/0032 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 33/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835640 Fleizach et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Gregory Knowles Fleizach (San Diego, California);  Christopher C. Pelham (Chula Vista, California);  Mark William Owen (San Diego, California)
ABSTRACT An apparatus and method identify emitters. The apparatus includes a receiver, a parameter estimator, a database, and a correlator. The receiver receives an electromagnetic signal from an emitter and measures actual values of observed parameters of the electromagnetic signal. The parameter estimator surmises surmised values of unobserved parameters from the actual values of the observed parameters. The actual values of the observed parameters and the surmised values of the unobserved parameters characterize the emitter. The database stores one or more entries for each emitter. Each entry specifies an identifier of an emitter and exemplary values of the observed and unobserved parameters. The correlator matches the actual values of the observed parameters and the surmised values of the unobserved parameters with the exemplary values of one of the entries of the emitter from which the receiver receives the electromagnetic signal. The correlator outputs the identifier from this entry in the database.
FILED Wednesday, April 21, 2021
APPL NO 17/236016
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/021 (20130101) Original (OR) Class
G01S 7/027 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835680 Groever et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Benedikt Groever (Cambridge, Massachusetts);  Wei-Ting Chen (Cambridge, Massachusetts);  Federico Capasso (Cambridge, Massachusetts)
ABSTRACT An optical device comprises a first meta-lens and a second meta-lens. The first meta-lens includes a first plurality of nanostructures that define a first phase profile of the first meta-lens. The second meta-lens includes a second plurality of nanostructures that define a second phase profile of the second meta-lens. A combination of the first meta-lens having the first phase profile and the second meta-lens having the second phase profile is configured to achieve a diffraction-limited focusing and correct an aberration of light transmitted through the optical device.
FILED Friday, May 04, 2018
APPL NO 16/610896
ART UNIT 2871 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101) Original (OR) Class
G02B 5/1809 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835681 Lin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts);  PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts);  PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Zin Lin (Boston, Massachusetts);  Federico Capasso (Cambridge, Massachusetts);  Alejandro W. Rodriquez (Princeton, New Jersey);  Marko Loncar (Belmont, Massachusetts);  Benedikt Groever (Somerville, Massachusetts)
ABSTRACT A multi-layered lens comprises a plurality of metasurface layers. At least some layers of the plurality of metasurface layers include features that exhibit angular phase controls. The angular phases of the at least some layers cause an angular aberration correction or an angle convergence that focuses light onto a focal point regardless of angles of incidence.
FILED Tuesday, June 19, 2018
APPL NO 16/623378
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/005 (20130101) Original (OR) Class
G02B 3/0087 (20130101)
G02B 27/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835707 Liang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Kaicheng Liang (Cambridge, Massachusetts);  James G. Fujimoto (Cambridge, Massachusetts);  Osman Oguz Ahsen (Cambridge, Massachusetts);  Michael Gene Giacomelli (Cambridge, Massachusetts);  Hsiang-Chieh Lee (Cambridge, Massachusetts);  Zhao Wang (Cambridge, Massachusetts)
ABSTRACT The present disclosure pertains to an apparatus and methods of an imaging device for obtaining images from the walls of luminal organs or a surgical cavity. The device is capable of passage through luminal organs or introduction into surgical cavities, and obtains images by rapidly scanning a focused light beam on the tissue to be imaged and receiving light from the tissue. The device comprises at least one mechanism for projecting a 2-dimensional (2-D) optical pattern, such as a 2-D scanner (508) or a 2-D optical array forming a closed loop scan pattern (506). The device comprises at least one other beam scanning mechanism, such as a rotary or angular scanner (510) such that cycloid scan pattern is formed on the surface to be scanned, and also has embodiments of focusing optics at different regimes of numerical aperture. The disclosure also describes methods for accurate image reconstruction with embodiments of hardware control and post-acquisition processing.
FILED Thursday, May 03, 2018
APPL NO 16/496371
ART UNIT 2425 — Cable and Television
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/00165 (20130101)
A61B 1/00172 (20130101)
A61B 1/00188 (20130101)
A61B 5/0066 (20130101)
A61B 5/0068 (20130101)

Optical Elements, Systems, or Apparatus
G02B 23/26 (20130101) Original (OR) Class
G02B 26/103 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835837 McManamon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Exciting Technology, LLC (Dayton, Ohio)
ASSIGNEE(S) Exciting Technology LLC (Dayton, Ohio)
INVENTOR(S) Paul F. McManamon (Dayton, Ohio);  Abtin Ataei (Dayton, Ohio)
ABSTRACT An example system includes a high-side electrode layer including a number of discrete electrodes and a low-side electrode layer. The system further includes an electro-optic (EO) layer including an EO active material positioned between the high-side electrode layer and the low-side electrode layer, thereby forming a number of active cells of the EO layer. Each of the number of active cells of the EO layer includes a portion of the EO layer that is positioned between one of the discrete electrodes and the low-side electrode layer. The example system further includes an insulator operationally coupled to the active cells of the EO layer, and at least partially positioned between a first one of the active cells and a second one of the active cells.
FILED Friday, August 21, 2020
APPL NO 16/999816
ART UNIT 2872 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0018 (20130101)
G02F 1/29 (20130101) Original (OR) Class
G02F 2201/12 (20130101)
G02F 2203/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835841 McManamon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Exciting Technology, LLC (Dayton, Ohio)
ASSIGNEE(S) Exciting Technology LLC (Dayton, Ohio)
INVENTOR(S) Paul F. McManamon (Dayton, Ohio);  Abtin Ataei (Dayton, Ohio)
ABSTRACT An example system includes a high-side electrode layer including a number of discrete electrodes and a low-side electrode layer. The system further includes an electro-optic (EO) layer including an EO active material positioned between the high-side electrode layer and the low-side electrode layer, thereby forming a number of active cells of the EO layer. Each of the number of active cells of the EO layer includes a portion of the EO layer that is positioned between one of the discrete electrodes and the low-side electrode layer. The example system further includes an insulator operationally coupled to the active cells of the EO layer, and at least partially positioned between a first one of the active cells and a second one of the active cells.
FILED Friday, August 21, 2020
APPL NO 16/999815
ART UNIT 2872 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/139 (20130101)
G02F 1/292 (20130101)
G02F 1/311 (20210101)
G02F 1/3133 (20130101) Original (OR) Class
G02F 1/3138 (20130101)
G02F 2203/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835842 Cousin et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) KAPTEYN MURNANE LABORATORIES, INC. (Boulder, Colorado)
ASSIGNEE(S) Regents of the Univ of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) Seth Lucien Cousin (Boulder, Colorado);  Michael Tanksalvala (Longmont, Colorado);  Henry C Kapteyn (Boulder, Colorado)
ABSTRACT Apparatus and methods for improved HHG of ultrashort pulse laser beams. A HHG assembly includes a gas distribution block and a waveguide cartridge having a HHG hollow core waveguide. The waveguide cartridge is attached to the gas distribution block and may be removed and replaced, while the gas distribution block remains affixed within the apparatus. The gas distribution block is configured to maintain a pressure profile within the hollow core fiber. The system also includes two operating beam sensors and two actuatable mirrors. The operating beam sensors are fixed with respect to the HHG assembly. The system is aligned before operation by adjusting the actuatable mirrors to optimize a sample beam through the waveguide and recording the position of the beam on the operating beam sensors. In operation, the mirrors are actuated to maintain the same positions of the input beam on the operating beam sensors.
FILED Monday, April 13, 2020
APPL NO 17/603233
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/281 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/353 (20130101)
G02F 1/354 (20210101)
G02F 1/365 (20130101)
G02F 1/3503 (20210101) Original (OR) Class
G02F 1/3555 (20130101)
G02F 2201/02 (20130101)
G02F 2201/58 (20130101)
G02F 2203/07 (20130101)
G02F 2203/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836576 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Shiqiang Wang (White Plains, New York);  Tiffany Tuor (London, United Kingdom);  Theodoros Salonidis (Boston, Massachusetts);  Christian Makaya (Summit, New Jersey);  Bong Jun Ko (Harrington Park, New Jersey)
ABSTRACT A training process of a machine learning model is executed at the edge node for a number of iterations to generate a model parameter based at least in part on a local dataset and a global model parameter. A resource parameter set indicative of resources available at the edge node is estimated. The model parameter and the resource parameter set are sent to a synchronization node. Updates to the global model parameter and the number of iterations are received from the synchronization node based at least in part on the model parameter and the resource parameter set of edge nodes. The training process of the machine learning model is repeated at the edge node to determine an update to the model parameter based at least in part on the local dataset and updates to the global model parameter and the number of iterations from the synchronization node.
FILED Friday, April 13, 2018
APPL NO 15/952625
ART UNIT 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/10 (20130101)
H04L 67/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836634 Nataraj et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Mayachitra, Inc. (Santa Barbara, California)
ASSIGNEE(S) Mayachitra, Inc. (Santa Barbara, California)
INVENTOR(S) Lakshmanan Nataraj (Chennai, India);  Tajuddin Manhar Mohammed (Goleta, California);  Tejaswi Nanjundaswamy (San Jose, California);  Michael Gene Goebel (Santa Barbara, California);  Bangalore S. Manjunath (Santa Barbara, California);  Shivkumar Chandrasekaran (Santa Barbara, California)
ABSTRACT Systems, devices, methods and instructions are described for detecting GAN generated images. On embodiment involves receiving an images, generating co-occurrence matrices on color channels of the image, generating analysis of the image by using a convolutional neural network trained to analyze image features of the images based on the generated co-occurrence matrices and determining whether the image is a GAN generated image based on the analysis.
FILED Tuesday, June 07, 2022
APPL NO 17/834455
ART UNIT 2631 — Digital Communications
CURRENT CPC
Electric Digital Data Processing
G06F 18/217 (20230101)
G06F 18/2148 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/045 (20230101)
G06N 3/088 (20130101) Original (OR) Class

Image or Video Recognition or Understanding
G06V 10/82 (20220101)
G06V 10/454 (20220101)
G06V 10/764 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836857 Young et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Transportation (USDOT)
Federal Highway Administration (FHWA)
National Highway Traffic Safety Administration (NHTSA)
APPLICANT(S) TRX Systems, Inc. (Greenbelt, Maryland)
ASSIGNEE(S) TRX Systems, Inc. (Greenbelt, Maryland)
INVENTOR(S) Travis Young (Rockville, Maryland);  Daniel Hakim (Silver Spring, Maryland);  Daniel Franchy (Catonsville, Maryland);  Jared Napora (Severn, Maryland);  John Karvounis (Bowie, Maryland);  Jonathan Fetter Degges (Washington, District of Columbia);  Tim Wang (Germantown, Maryland);  Benjamin Funk (Hanover, Maryland);  Carole Teolis (Glendale, Maryland);  Carol Politi (Bethesda, Maryland);  Stuart Woodbury (Ellicott City, Maryland)
ABSTRACT Systems, methods and instructions for creating building models of physical structures is disclosed. The building model may be a collection of floors defined by outlines containing regions that may be offset relative to a main region, and a collection of connectors. Connectors may have connection points for tracking, routing and sizing. Connectors may indicate elevation changes through georeferenced structural features. Signal elements may also be features that provide corrections when tracking. Feature descriptors are data that describes the structural configuration and signal elements enabling them to be matched to previously collected data in a database. User interface elements assist a user of a tracking device in collecting floor information, structural features and signal features and validating certain collected information based on previously known information. The height of floors may also be inferred based on sensor data from the tracking device.
FILED Wednesday, August 03, 2022
APPL NO 17/880530
ART UNIT 2617 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3867 (20200801)

Electric Digital Data Processing
G06F 30/13 (20200101)

Image Data Processing or Generation, in General
G06T 17/05 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837629 Lichtenwalner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Wolfspeed, Inc. (Durham, North Carolina)
ASSIGNEE(S) Wolfspeed, Inc. (Durham, North Carolina)
INVENTOR(S) Daniel J. Lichtenwalner (Raleigh, North Carolina);  Edward R. Van Brunt (Raleigh, North Carolina);  Brett Hull (Raleigh, North Carolina)
ABSTRACT Semiconductor devices include a semiconductor layer structure comprising a drift region that includes a wide band-gap semiconductor material. A shielding pattern is provided in an upper portion of the drift region in an active region of the device and a termination structure is provided in the upper portion of the drift region in a termination region of the device. A gate trench extends into an upper surface of the semiconductor layer structure. The semiconductor layer structure includes a semiconductor layer that extends above and at least partially covers the termination structure.
FILED Thursday, November 19, 2020
APPL NO 16/952757
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/046 (20130101)
H01L 29/063 (20130101) Original (OR) Class
H01L 29/0615 (20130101)
H01L 29/0619 (20130101)
H01L 29/0623 (20130101)
H01L 29/0696 (20130101)
H01L 29/0878 (20130101)
H01L 29/1037 (20130101)
H01L 29/1095 (20130101)
H01L 29/1608 (20130101)
H01L 29/7397 (20130101)
H01L 29/7811 (20130101)
H01L 29/7813 (20130101)
H01L 29/66068 (20130101)
H01L 29/66734 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837701 Eskra et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Tank Automotive Research, Development and Engineering Center (TARDEC)
APPLICANT(S) Eskra Technical Products, Inc. (Saukville, Wisconsin)
ASSIGNEE(S) Eskra Technical Products, Inc. (Saukville, Wisconsin)
INVENTOR(S) Michael David Eskra (Saukville, Wisconsin);  Paula Margaret Ralston (Frederick, Maryland);  Richard Thomas Johnson (Howard, Colorado)
ABSTRACT A bipolar lead acid battery with increased energy density is provided. The battery includes a number of lead acid wafer cell that each comprise a negative electrode having a negative electrode plate and a negative active material positioned on the negative electrode plate, as well as a positive electrode having a positive electrode plate and a positive active material positioned on the positive electrode plate. The positive electrode plate comprises a metal foil with a conductive film thereon, such as a titanium foil or substrate with a titanium silicide coating thereon. The lead acid wafer cell also includes a separator between the negative and positive electrodes, wherein the separator includes an electrolyte for transferring charge between the negative and positive electrodes.
FILED Monday, June 28, 2021
APPL NO 17/304863
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/14 (20130101)
H01M 4/624 (20130101)
H01M 4/661 (20130101)
H01M 4/667 (20130101)
H01M 10/10 (20130101)
H01M 10/18 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837873 Isobe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Hiroki Isobe (Cambridge, Massachusetts);  Qiong Ma (Allston, Massachusetts);  Liang Fu (Winchester, Massachusetts);  Nuh Gedik (Watertown, Massachusetts);  Suyang Xu (Allston, Massachusetts);  Pablo Jarillo-Herrero (Cambridge, Massachusetts)
ABSTRACT Rectification is a process that converts electromagnetic fields into direct current (DC). Such a process underlies a wide range of technologies, including wireless communication, wireless charging, energy harvesting, and infrared detection. Existing rectifiers are mostly based on semiconductor diodes, with limited applicability to small voltages or high frequency inputs. Here, we present an alternative approach to current rectification that uses the electronic properties of quantum crystals without semiconductor junctions. We identify a new mechanism for rectification from skew scattering due to the chirality of itinerant electrons in time-reversal-invariant but inversion-breaking materials. Our calculations reveal large, tunable rectification effects in graphene multilayers and transition metal dichalcogenides. These effects can be used in high-frequency rectifiers by rational material design and quantum wavefunction engineering.
FILED Friday, June 11, 2021
APPL NO 17/345078
ART UNIT 2839 — Electrical Circuits and Systems
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/001 (20200101) Original (OR) Class
H02J 50/27 (20160201)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/4208 (20130101)
H02M 7/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11838040 Medard et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  National University of Ireland, Maynooth (Maynooth, Ireland)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  National University of Ireland, Maynooth (Maynooth, Ireland)
INVENTOR(S) Muriel Medard (Belmont, Massachusetts);  Kenneth R. Duffy (Dublin, Ireland);  Amit Solomon (Cambridge, Massachusetts);  Alejandro Cohen (Brookline, Massachusetts)
ABSTRACT Described are concepts, systems, devices and methods that enhance decoding performance of channels subject to correlated noise. The concepts, systems, devices and methods can be used with any combination of codes, code-rates and decoding techniques. In embodiments, a continuous realization of effective noise is estimated from a lead channel by subtracting its decoded output from its received signal. This estimate is then used to improve the accuracy of decoding of an otherwise orthogonal channel that is experiencing correlated effective noise. In this approach, channels aid each other through the post-decoding provision of estimates of effective noise. In some embodiments, the lead channel is not pre-determined, but is chosen dynamically based on which of a plurality of decoders completes first, or using soft information including an estimate of effective noise that is least energetic or most likely to have occurred.
FILED Friday, July 22, 2022
APPL NO 17/814349
ART UNIT 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission
H04B 1/123 (20130101) Original (OR) Class
H04B 1/1027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11838094 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Gov of the US as Rep by the Secy of the Air Force (WPAFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Joseph Anderson (Edwards, California);  Nicholas Black (Charlotte, North Carolina);  Michael Anderson (Colorado Springs, Colorado)
ABSTRACT A repeater for maintaining wireless line of sight communications. The repeater is autonomously repositional in both absolute location and azimuthal orientation. The repeater has at least two vibratory motors, or other vibration sources, which provide oscillations to depending legs against a support surface. By selectively operating one or more of the vibration sources together or independently, the repeater may be moved as helpful to maintain line of sight communication with another repeater or other operational hardware. A command signal from a remote base station controls the locomotion of the repeater to provide both a change in absolute position relative to the surroundings and a rotational change in azimuthal orientation as necessary to maintain communication under dynamic conditions.
FILED Wednesday, March 23, 2022
APPL NO 17/656175
ART UNIT 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission
H04B 7/155 (20130101) Original (OR) Class
H04B 7/2606 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11833488 Biener et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Juergen Biener (San Leandro, California);  Arne Wittstock (Livermore, California);  Monika M. Biener (San Leandro, California);  Michael Bagge-Hansen (Livermore, California);  Marcus Baeumer (Bremen, Germany);  Andre Wichmann (Bremen, Germany);  Bjoern Neuman (Hamburg, Germany)
ABSTRACT In one embodiment, a product includes a nanoporous gold structure comprising a plurality of ligaments, and a plurality of oxide particles deposited on the nanoporous gold structure; the oxide particles are characterized by a crystalline phase.
FILED Thursday, July 11, 2019
APPL NO 16/509366
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/885 (20130101)
B01D 53/945 (20130101)
B01D 2255/40 (20130101)
B01D 2255/106 (20130101)
B01D 2255/802 (20130101)
B01D 2255/2065 (20130101)
B01D 2255/2066 (20130101)
B01D 2255/9202 (20130101)
B01D 2255/9207 (20130101)
B01D 2255/20707 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/063 (20130101)
B01J 23/10 (20130101)
B01J 23/52 (20130101)
B01J 23/66 (20130101) Original (OR) Class
B01J 23/745 (20130101)
B01J 23/8906 (20130101)
B01J 35/002 (20130101)
B01J 35/004 (20130101)
B01J 35/0006 (20130101)
B01J 35/006 (20130101)
B01J 35/0013 (20130101)
B01J 35/1009 (20130101)
B01J 35/1014 (20130101)
B01J 35/1061 (20130101)
B01J 37/08 (20130101)
B01J 37/0201 (20130101)
B01J 37/0207 (20130101)
B01J 37/0217 (20130101)
B01J 37/0225 (20130101)
B01J 37/342 (20130101)
B01J 37/349 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 2203/044 (20130101)

Climate Change Mitigation Technologies Related to Transportation
Y02T 10/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833494 Gunnoe et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Thomas B. Gunnoe (Palmyra, Virginia);  Benjamin Austin Vaughan (Dover, New Hampshire);  Michael S. Webster-Gardiner (Mims, Florida)
ABSTRACT Embodiments of the present disclosure provide for Rh(I) catalysts, methods of making alkenyl substituted arenes (e.g., allyl arene, vinyl arene, and the like), methods of making alkyl substituted arenes, and the like.
FILED Thursday, February 02, 2023
APPL NO 18/163647
ART UNIT 1738 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/00 (20130101)
B01J 31/189 (20130101)
B01J 31/1815 (20130101) Original (OR) Class
B01J 31/2226 (20130101)
B01J 31/2291 (20130101)
B01J 2231/46 (20130101)
B01J 2531/0244 (20130101)
B01J 2531/822 (20130101)
B01J 2540/22 (20130101)
B01J 2540/225 (20130101)

Acyclic or Carbocyclic Compounds
C07C 2/66 (20130101)
C07C 2/66 (20130101)
C07C 2/66 (20130101)
C07C 5/03 (20130101)
C07C 5/03 (20130101)
C07C 5/03 (20130101)
C07C 15/46 (20130101)
C07C 15/58 (20130101)
C07C 15/58 (20130101)
C07C 15/073 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833583 Watts et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Seth Evan Watts (Collingswood, New Jersey);  Nikola Dudukovic (Hayward, California);  Eric Duoss (Danville, California)
ABSTRACT The present disclosure relates to a plurality of powder particles configured to be joined in an additive manufacturing process to form a part. Each one of the powder particles has a determined three dimensional, non-spherical shape. The plurality of powder particles are further of dimensions enabling fitting individual ones of the powder particles in abutting relationship with one another. At least a subplurality of the powder particles each have a functionalized surface feature to enhance at least one of clustering or separation of the subplurality of powder particles.
FILED Thursday, June 16, 2022
APPL NO 17/841769
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/06 (20220101) Original (OR) Class
B22F 10/00 (20210101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833762 Cook et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Adam W. Cook (Albuquerque, New Mexico);  Mathias C. Celina (Albuquerque, New Mexico);  Carl Erik Linde (Albuquerque, New Mexico);  Leah N. Appelhans (Tijeras, New Mexico);  Devin J. Roach (Albuquerque, New Mexico)
ABSTRACT Direct ink write (DIW) printing of reactive resins presents a unique challenge due to the time-dependent nature of the rheological and chemical properties of the ink. As a result, careful print optimization or process control is important to obtain consistent, high quality prints. The present invention uses a flow-through characterization cell for in situ chemical monitoring of a resin ink during DIW printing. Additionally, in-line extrusion force monitoring can be combined with off-line post inspection using machine vision. By combining in-line spectroscopy and force monitoring, it is possible to follow reaction kinetics (for example, curing of a reactive resin) and viscosity changes during printing, which can be used for a closed-loop process control. Additionally, the capability of machine vision to automatically identify and quantify print artifacts can be incorporated on the printing line to enable real-time, AI-assisted quality control of the printed products. Together, these techniques can form the building blocks of an optimized process control strategy when complex reactive ink must be used to produce printed hardware.
FILED Monday, October 17, 2022
APPL NO 17/967083
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/124 (20170801)
B29C 64/264 (20170801)
B29C 64/393 (20170801) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833902 Narula et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) CUMMINS INC. (Columbus, Indiana)
ASSIGNEE(S) Cummins Inc. (Columbus, Indiana)
INVENTOR(S) Manik Narula (Columbus, Indiana);  Timothy C. Ernst (Columbus, Indiana);  Michael J. Ruth (Franklin, Indiana);  Jonathan A. Dickson (Columbus, Indiana);  J. Steven Kolhouse (Columbus, Indiana);  Nimish Bagayatkar (Carmel, Indiana)
ABSTRACT A vehicle system includes an engine, a transmission, a differential, and a waste heat recovery (WHR) drive that converts thermal energy into mechanical and electrical energy. The WHR drive can include a WHR power unit structured to convert thermal energy into rotation of a WHR drive shaft. A motor/generator having a motor/generator shaft can selectively operate as a motor or a generator. A mechanical linkage is structured to selectively link an output shaft to one of the WHR drive shaft and the motor/generator drive shaft independently of the other of the WHR drive shaft and the motor/generator drive shaft. The output shaft is selectively coupled to one of the engine, the transmission, or the differential. The vehicle system may also include a traction motor to provide drive to the vehicle. The output shaft can be selectively coupled to the traction motor or the engine.
FILED Wednesday, February 27, 2019
APPL NO 16/976213
ART UNIT 3618 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 6/32 (20130101) Original (OR) Class
B60K 6/46 (20130101)

Hot Gas or Combustion-product Positive-displacement Engine Plants; Use of Waste Heat of Combustion Engines; Not Otherwise Provided for
F02G 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834544 Yandrasits et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) 3M Innovative Properties Company (St. Paul, Minnesota);  The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) 3M Innovative Properties Company (Saint Paul, Minnesota);  The Penn State Research Foundation (University Park, Panama)
INVENTOR(S) Michael A. Yandrasits (Hastings, Minnesota);  Carl A. Laskowski (Minneapolis, Minnesota);  Timothy M. Gillard (St. Paul, Minnesota);  Michael Hickner (State College, Pennsylvania);  Liang Zhu (Boca Raton, Florida)
ABSTRACT Described herein are cationic polymers having a plurality of quaternary amino groups, methods of making such polymers, and uses of such polymers as ion exchange membranes in electrochemical devices.
FILED Monday, March 11, 2019
APPL NO 16/980320
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/32 (20130101) Original (OR) Class
C08F 8/44 (20130101)
C08F 210/08 (20130101)
C08F 212/12 (20130101)
C08F 214/16 (20130101)
C08F 214/18 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/2243 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/1004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834550 Bae et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Rensselaer Polytechnic Institute (Troy, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Chulsung Bae (Cohoes, New York);  Woo-Hyung Lee (Troy, New York)
ABSTRACT Embodiments of the invention relate to a novel class of polymers with superior mechanical properties and chemical stability, as compared to known polymers. These polymers are particularly well suited for use in anion exchange membranes (AEMs), including those employed in fuel cells. Novel methods for the manufacture of these polymers are also described.
FILED Wednesday, February 23, 2022
APPL NO 17/652175
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 29/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 10/00 (20130101)
C08G 61/02 (20130101) Original (OR) Class
C08G 2261/20 (20130101)
C08G 2261/45 (20130101)
C08G 2261/124 (20130101)
C08G 2261/146 (20130101)
C08G 2261/312 (20130101)
C08G 2261/332 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/14 (20130101)
C09D 165/00 (20130101)

Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 13/08 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 8/1004 (20130101)
H01M 8/1039 (20130101)
H01M 8/1072 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834650 Ruffing et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Anne Ruffing (Albuquerque, New Mexico);  Darren W. Branch (Albuquerque, New Mexico);  Ronald P. Manginell (Albuquerque, New Mexico)
ABSTRACT The present invention relates to methods of transforming a cell by use of an acoustic transducer. In particular embodiments, the radiofrequency signal to the transducer can be tuned to provide optimal membrane disruption of the cell; and an agent, such as a nucleic acid, can then be delivered to the cell.
FILED Thursday, June 20, 2019
APPL NO 16/446971
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 35/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 13/00 (20130101) Original (OR) Class
C12N 15/87 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834741 Prinz et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Friedrich B. Prinz (Stanford, California);  Shicheng Xu (Stanford, California);  Timothy English (Stanford, California);  John Provine (Stanford, California);  Dickson Thian (Stanford, California);  Jan Torgersen (Stanford, California)
ABSTRACT A method includes: 1) performing an atomic layer deposition cycle including (a) introducing precursors into a deposition chamber housing a substrate to deposit a material on the substrate; and (b) introducing a passivation gas into the deposition chamber to passivate a surface of the material; and 2) repeating 1) a plurality of times to form a film of the material.
FILED Thursday, September 07, 2017
APPL NO 16/331391
ART UNIT 1718 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/42 (20130101)
B01J 35/10 (20130101)
B01J 37/349 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/18 (20130101)
C23C 16/0245 (20130101)
C23C 16/45534 (20130101) Original (OR) Class
C23C 16/45553 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834746 Freiderich
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
National Security Complex and PANTEX Plant (Y-12)
NNSA Critical Mission Site
Operated by Consolidated Nuclear Security, LLC at Oak Ridge, TN (CNS)
APPLICANT(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Melissa Ensor Freiderich (Oak Ridge, Tennessee)
ABSTRACT Systems and methods for electroless plating a first metal onto a second metal in a molten salt bath including: a bath vessel holding a dry salt mixture including a dry salt medium and a dry salt medium of the first metal, and without the reductant therein, the dry salt mixture configured to be heated to form a molten salt bath; and the second metal is configured to be disposed in the molten salt bath and receive a pure coating of the first metal thereon by electroless plating in the molten salt bath, wherein the second metal is more electronegative than the first metal.
FILED Monday, October 10, 2022
APPL NO 17/962598
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Apparatus for Applying Fluent Materials to Surfaces, in General
B05C 3/02 (20130101)
B05C 3/005 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 18/31 (20130101) Original (OR) Class
C23C 18/1619 (20130101)
C23C 18/1628 (20130101)
C23C 18/1637 (20130101)
C23C 18/1676 (20130101)

Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor
C25F 3/02 (20130101)
C25F 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835300 Lance et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Blake Lance (Albuquerque, New Mexico);  Clifford K. Ho (Albuquerque, New Mexico);  Kevin Albrecht (Albuquerque, New Mexico)
ABSTRACT Apparatus for cooling a hot fluid by transferring heat to particles that are then cooled by air.
FILED Thursday, May 02, 2019
APPL NO 16/618711
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 20/023 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835387 Nguyen et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Hoang T. Nguyen (Livermore, California);  Michael C. Rushford (Livermore, California)
ABSTRACT A spectral beam combining system includes a spectral channel splicer comprising a plurality of reflectors and a spectral beam combiner comprising a diffraction optical element such as a diffraction grating. This spectral beam combining system may facilitate combining an increased number of spectral channels thereby producing higher optical power of the combining beam system.
FILED Thursday, December 02, 2021
APPL NO 17/457417
ART UNIT 2877 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/10 (20130101)
G01J 3/18 (20130101)
G01J 3/021 (20130101)
G01J 3/0208 (20130101) Original (OR) Class
G01J 2003/102 (20130101)
G01J 2003/1861 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835464 Bol′shakov et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Applied Spectra, Inc. (, None)
ASSIGNEE(S) Applied Spectra, INC. (West Sacramento, California)
INVENTOR(S) Alexander A. Bol′shakov (Union City, California);  Chunyi Liu (Fremont, California);  Sudeep J. Pandey (Sacramento, California);  Richard E. Russo (Walnut Creek, California)
ABSTRACT Chemical composition of liquid phase samples is determined based on laser induced ablation spectroscopy of droplets. An aerosol jet comprising a carrier gas and liquid phase sample droplets, less than about 10 microns in diameter, is formed. An emissive plasma plume is generated from the sample droplets using a pulsed laser to deposit energy at a focal point in the aerosol jet. Light from the plasma plume is gathered with a concave mirror and focused into one end of a fiber optic lightguide. The lightguide can transmit spectral emissions from the plume to a spectrometer/detector which can send wavelength and intensity values to a computer. The computer is operable to determine a liquid sample composition based on the wavelength and intensity values.
FILED Tuesday, February 15, 2022
APPL NO 17/672678
ART UNIT 2877 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/718 (20130101) Original (OR) Class
G01N 2201/08 (20130101)
G01N 2201/0636 (20130101)
G01N 2201/06113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835545 McLeod et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Alexander Swinton McLeod (New York, New York);  Lin Xiong (Bronx, New York);  Shuai Zhang (New York, New York);  Dimitri N. Basov (New York, New York)
ABSTRACT An exemplary apparatus can provide radiation to a sample(s), which can include, for example, a radiation source arrangement configured to provide radiation, a beam splitter configured to split the radiation into (i) a first radiation, and (ii) a second radiation. An optical element can also be provided which, in operation, can, e.g., (a) receive the first radiation and the second radiation, (b) reflect the first radiation as a reference radiation, (c) provide the second radiation as illumination for the sample(s), (d) receive a resultant radiation from the sample(s) that can be based on the illumination from the second radiation, and (e) provide the reference radiation and the resultant radiation to be detected and used for interferometric imaging or spectroscopy.
FILED Thursday, January 14, 2021
APPL NO 17/149236
ART UNIT 2881 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02 (20130101)

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 20/02 (20130101) Original (OR) Class
G01Q 30/18 (20130101)
G01Q 60/24 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/0032 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 33/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835743 Nguyen
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Hoang T. Nguyen (Livermore, California)
ABSTRACT Optical structures, including thin film designs and components with topography, are provided that achieve significantly improved laser damage thresholds and/or ultra-low-loss. These advances may be achieved by utilizing a bulk window including a material having a band gap that is at least 5.0 eV and a thickness. The bulk window can be configured to increase the laser induced damage threshold of the underlying optical structure.
FILED Wednesday, February 10, 2021
APPL NO 17/172979
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/1833 (20130101)
G02B 5/1847 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837389 Landa et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Alexander Landa (Livermore, California);  Per Soderlind (Oakland, California);  Emily Moore (Livermore, California);  Aurelien Perron (Pleasanton, California)
ABSTRACT In accordance with one aspect of the presently disclosed inventive concepts, a magnet includes a material having a chemical formula: YFe3(Ni1-xCox)2, where x is greater than 0 and x is less than 1.
FILED Tuesday, August 10, 2021
APPL NO 17/398905
ART UNIT 1738 — Audio Signals
CURRENT CPC
Alloys
C22C 30/00 (20130101)
C22C 2202/02 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/047 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837393 Wang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Jian-Ping Wang (Shoreview, Minnesota);  Bin Ma (Roseville, Minnesota);  Jinming Liu (Minneapolis, Minnesota);  Yiming Wu (Shoreview, Minnesota);  YanFeng Jiang (Minneapolis, Minnesota)
ABSTRACT Example nanoparticles may include an iron-based core, and a shell. The shell may include a non-magnetic, anti-ferromagnetic, or ferrimagnetic material. Example alloy compositions may include an iron-based grain, and a grain boundary. The grain boundary may include a non-magnetic, anti-ferromagnetic, or ferrimagnetic material. Example techniques for forming iron-based core-shell nanoparticles may include depositing a shell on an iron-based core. The depositing may include immersing the iron-based core in a salt composition for a predetermined period of time. The depositing may include milling the iron-based core with a salt composition for a predetermined period of time. Example techniques for treating a composition comprising core-shell nanoparticles may include nitriding the composition.
FILED Thursday, September 30, 2021
APPL NO 17/490800
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/06 (20220101)
B22F 1/054 (20220101)
B22F 1/0547 (20220101)
B22F 1/0553 (20220101)
B22F 9/04 (20130101)
B22F 2301/35 (20130101)
B22F 2302/20 (20130101)
B22F 2304/054 (20130101)

Alloys
C22C 38/00 (20130101)
C22C 38/001 (20130101)
C22C 38/10 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 8/26 (20130101)
C23C 8/50 (20130101)
C23C 8/80 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/059 (20130101)
H01F 1/061 (20130101)
H01F 1/065 (20130101) Original (OR) Class
H01F 1/0551 (20130101)
H01F 1/0552 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837432 Nogan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) John Joseph Nogan (Albuquerque, New Mexico);  Katherine Leigh Jungjohann (Sandia Park, New Mexico);  Raymond Vernon Puckett (Albuquerque, New Mexico)
ABSTRACT A portable, compact gas delivery system can support an environmental transmission electron microscope. Environment transmission electron microscopy provides researchers a unique capability of assessing a material's surface conditions at atomic resolution in a variety of reactive and oxidizing environments. The ability to precisely control the analysis chamber's environmental conditions over time is key to the success of a typical surface analysis. The gas delivery system provides the correct balance or pressure delivery precision, contamination control, and gas isolation.
FILED Wednesday, November 25, 2020
APPL NO 17/104299
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/261 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837865 Qi et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) ABB S.p.A. (Sesto San Giovanni, Italy)
ASSIGNEE(S) ABB S.p.A. (Milan, Italy)
INVENTOR(S) Li Qi (Cary, North Carolina);  Yuzhi Zhang (Apex, North Carolina);  Taosha Jiang (Cary, North Carolina)
ABSTRACT In one aspect, a hybrid circuit protection device for current-limiting a fault current between a source and a load during a fault is provided. The hybrid circuit protection device includes an input configured to couple to the source, an output configured to couple to the load, a return configured to couple the source to the load, a main switch configured to selectively couple the input to the output, a switching network coupled in parallel with the main switch, and a controller. The controller is configured to determine that the main switch has opened in response to the fault current, where the fault current has an initial value, and activate the switching network to current-limit the fault current to less than the initial value during the fault.
FILED Tuesday, December 21, 2021
APPL NO 17/557258
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electric Switches; Relays; Selectors; Emergency Protective Devices
H01H 9/542 (20130101)

Emergency Protective Circuit Arrangements
H02H 1/0007 (20130101)
H02H 9/02 (20130101) Original (OR) Class

Pulse Technique
H03K 3/017 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837873 Isobe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Hiroki Isobe (Cambridge, Massachusetts);  Qiong Ma (Allston, Massachusetts);  Liang Fu (Winchester, Massachusetts);  Nuh Gedik (Watertown, Massachusetts);  Suyang Xu (Allston, Massachusetts);  Pablo Jarillo-Herrero (Cambridge, Massachusetts)
ABSTRACT Rectification is a process that converts electromagnetic fields into direct current (DC). Such a process underlies a wide range of technologies, including wireless communication, wireless charging, energy harvesting, and infrared detection. Existing rectifiers are mostly based on semiconductor diodes, with limited applicability to small voltages or high frequency inputs. Here, we present an alternative approach to current rectification that uses the electronic properties of quantum crystals without semiconductor junctions. We identify a new mechanism for rectification from skew scattering due to the chirality of itinerant electrons in time-reversal-invariant but inversion-breaking materials. Our calculations reveal large, tunable rectification effects in graphene multilayers and transition metal dichalcogenides. These effects can be used in high-frequency rectifiers by rational material design and quantum wavefunction engineering.
FILED Friday, June 11, 2021
APPL NO 17/345078
ART UNIT 2839 — Electrical Circuits and Systems
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/001 (20200101) Original (OR) Class
H02J 50/27 (20160201)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/4208 (20130101)
H02M 7/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11838021 Barlow et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Matthew Barlow (Springdale, Arkansas);  James A. Holmes (Fayetteville, Arkansas)
ASSIGNEE(S)
INVENTOR(S) Matthew Barlow (Springdale, Arkansas);  James A. Holmes (Fayetteville, Arkansas)
ABSTRACT An improved electrical circuit for logic output level shifting using SiC JFETs with resistors on the input, inverting, stage and using diode degenerated JFET sources in the output stage.
FILED Tuesday, April 13, 2021
APPL NO 17/229277
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Pulse Technique
H03K 19/09 (20130101)
H03K 19/09403 (20130101) Original (OR) Class
H03K 19/09425 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11838666 Fahim et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Fermi National Accelerator Laboratory (FNAL)
Federally Funded Research and Development Center (FFRDC)
Operated by Fermi Research Alliance, LLC (FRA) at Batavia, IL
APPLICANT(S) Fermi Research Alliance, LLC (Batavia, Illinois)
ASSIGNEE(S) Fermi Research Alliance, LLC (Batavia, Illinois)
INVENTOR(S) Farah Fahim (Glen Ellyn, Illinois);  Tom Zimmerman (St. Charles, Illinois);  Grzegorz Deptuch (Forest Park, Illinois)
ABSTRACT A compact ADC circuit can include one or more comparators, and a serial DAC (Digital-to-Analog) circuit that provides a signal to the comparator (or comparators). In addition, the ADC circuit can include a serial DAC redistribution sequencer that can provide a plurality of signals as input to the serial DAC circuit and is subject to a redistribution cycle and which receives as input a signal from a data multiplexer whose input connects electronically to an output of the comparator. The circuit can further include an ADC code register that provides an ADC output that connects electronically to the output of the comparator and the input to the data multiplexer. Shared logic circuitry for sharing common logic between pixels can be included, wherein the shared logic circuitry connects electronically to the data multiplexer and the ADC code register, wherein the shared logic circuitry promotes area and power savings for the pixel detector circuit.
FILED Wednesday, August 04, 2021
APPL NO 17/394351
ART UNIT 2697 — Selective Visual Display Systems
CURRENT CPC
Pulse Technique
H03K 5/2472 (20130101)

Coding; Decoding; Code Conversion in General
H03M 1/462 (20130101)
H03M 1/466 (20130101)

Pictorial Communication, e.g Television
H04N 25/75 (20230101) Original (OR) Class
H04N 25/709 (20230101)
H04N 25/766 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11839016 Tang et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Vincent Tang (Dublin, California);  Glenn A. Meyer (Danville, California);  Steven Falabella (Livermore, California);  Gary Guethlein (Livermore, California);  Brian Rusnak (Livermore, California);  Stephen Sampayan (Manteca, California);  Christopher Spadaccini (Oakland, California);  Li-Fang Wang (Livermore, California);  John Harris (Monterey, California);  Jeff Morse (Westhampton, Massachusetts)
ABSTRACT A method for producing a neutrons includes producing a voltage of negative polarity of at least −100 keV on a surface of a deuterated or tritiated target in response to a temperature change of a pyroelectric crystal of less than about 40° C., the pyroelectric crystal having the deuterated or tritiated target coupled thereto, pulsing a deuterium ion source to produce a deuterium ion beam, accelerating the deuterium ion beam to the deuterated or tritiated target, and directing the ion beam onto the deuterated or tritiated target to make neutrons using at least one element of the following: a voltage of the pyroelectric crystal and a high gradient insulator (HGI) surrounding the pyroelectric crystal. The accelerating of the deuterium ion beam is achieved by using an ion accelerating mechanism comprising a pyroelectric stack accelerator having a first thermal altering mechanism for changing a temperature of the pyroelectric stack accelerator.
FILED Tuesday, December 15, 2020
APPL NO 17/122918
ART UNIT 3619 — Selective Visual Display Systems
CURRENT CPC
Conversion of Chemical Elements; Radioactive Sources
G21G 4/02 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 3/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11839168 Brown et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S) United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Kevin Brown (Stony Brook, New York);  Thomas Roser (Huntington, New York)
ABSTRACT A system and method for storing information in a quantum computer using a quantum storage ring. The method comprises cooling ions in the quantum storage ring to a low temperature; and binding the ions into a lattice structure, forming an ion Coulomb crystal.
FILED Thursday, September 29, 2022
APPL NO 17/956492
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Static Stores
G11C 11/54 (20130101)

Electric solid-state devices not otherwise provided for
H10N 99/05 (20230201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11832601 Metcalf et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Eye Institute (NEI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Child Health and Human Development (NICHD)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) VANDERBILT UNIVERSITY (Nashville, Tennessee);  YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee);  YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Jason Metcalf (Dexter, Michigan);  Seth R. Bordenstein (Nashville, Tennessee);  Daniel Lepage (Centertown, Missouri);  Sarah Bordenstein (Nashville, Tennessee);  Mark Hochstrasser (Hamden, Connecticut);  John F. Beckmann (New Haven, Connecticut);  Judith Ronau (Hamden, Connecticut)
ABSTRACT The disclosure relates to genetically modified bacteria, genetically modified arthropods, and methods for controlling and/or reducing arthropod populations.
FILED Friday, June 09, 2017
APPL NO 16/307982
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0337 (20130101) Original (OR) Class
A01K 67/0339 (20130101)
A01K 2217/052 (20130101)
A01K 2217/206 (20130101)
A01K 2227/706 (20130101)
A01K 2267/02 (20130101)

Peptides
C07K 14/195 (20130101)
C07K 2319/21 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/205 (20210501)
C12N 9/22 (20130101)
C12N 9/6472 (20130101)
C12N 15/87 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/01 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11832801 Katchman et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) cARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Benjamin Katchman (Tempe, Arizona);  Karen Anderson (Scottsdale, Arizona);  Jennifer Blain Christen (Chandler, Arizona)
ABSTRACT Provided herein are methods of detecting and measuring disease-associated analytes such as proteins and antibodies in a sweat sample. Also provided are methods of determining and monitoring the disease state or physiological condition of a subject using small sweat samples.
FILED Tuesday, July 11, 2017
APPL NO 16/317326
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 10/0064 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/17 (20130101)
G01N 33/56994 (20130101)
G01N 2333/05 (20130101)
G01N 2333/11 (20130101)
G01N 2469/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11832871 Farritor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Telemedicine and Advanced Technology Research Center (TATRC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Office of The Director (OD)
Experimental Program to Stimulate Competitive Research (EPS)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Shane Farritor (Lincoln, Nebraska);  Tom Frederick (Gretna, Nebraska);  Joe Bartels (Pittsburgh, Pennsylvania)
ABSTRACT The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices, and more specifically including end effectors that can be incorporated into such devices. Certain end effector embodiments include various vessel cautery devices that have rotational movement as well as cautery and cutting functions while maintaining a relatively compact structure. Other end effector embodiments include various end effector devices that have more than one end effector.
FILED Monday, June 21, 2021
APPL NO 17/352817
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/1445 (20130101) Original (OR) Class
A61B 34/30 (20160201)
A61B 2018/0063 (20130101)
A61B 2018/00345 (20130101)
A61B 2018/00595 (20130101)
A61B 2018/1455 (20130101)
A61B 2034/301 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11832915 Melodia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Research Foundation for The State University of New York (Amherst, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Amherst, New York)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Zhangyu Guan (Boston, Massachusetts);  Giuseppe Enrico Santagati (Cambridge, Massachusetts)
ABSTRACT Methods for ultrasonic communications through biological tissue using ultrasonic pulses are disclosed. For example, methods for calculating a forward data generation rate and a forward transmission probability profile for ultrasonic communications through biological material are disclosed. The method may comprise measuring sets interference values corresponding to instants on a communication channel. First and second order moments may be calculated for each instant based on the measured interference values. An outage probability may be calculated for each set and the forward data generation rate and forward transmission probability profile may be calculated based on the outage probability value and other parameters and a threshold transmission rate, a transmission delay threshold, and a residual transmission error rate.
FILED Tuesday, December 17, 2019
APPL NO 16/717591
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0015 (20130101)
A61B 5/0024 (20130101)
A61B 5/0028 (20130101) Original (OR) Class
A61B 5/0031 (20130101)
A61B 5/0205 (20130101)
A61B 5/7203 (20130101)
A61B 5/7225 (20130101)
A61B 5/14532 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/14244 (20130101)

Transmission
H04B 11/00 (20130101)
H04B 17/15 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833254 Bahal et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Connecticut (Farmington, Connecticut)
ASSIGNEE(S) UNIVERSITY OF CONNECTICUT (Farmington, Connecticut)
INVENTOR(S) Raman Bahal (Glastonbury, Connecticut);  Mu-Ping Nieh (Mansfield, Connecticut);  Armin Tahmasbi Rad (Manchester, Connecticut);  Shipra Malik (Storrs, Connecticut)
ABSTRACT A self-assembled discoidal PNA delivery vehicle includes a zwitterionic short chain diacyl lipid, a zwitterionic long chain diacyl lipid, a charged long chain diacyl lipid, a PEGylated lipid of the formula distearoyl phosphoethanolamine (DSPE)-PEGn-TG, and an encapsulated PNA molecule with a defined molar ratio of the zwitterionic long chain diacyl lipid and the charged long chain diacyl lipid to the short chain diacyl lipid, the molar ratio of the charged long chain diacyl lipid to the zwitterionic long chain diacyl lipid, molar % of the PEGylated lipid to all lipids, and ratio of PNA to lipid. Also described are method of self-assembling the discoidal PNA delivery vehicle and methods of enhancing cellular uptake of PNA using the discoidal PNA delivery vehicle.
FILED Thursday, May 27, 2021
APPL NO 17/332258
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/146 (20130101)
A61K 9/1271 (20130101)
A61K 9/1274 (20130101)
A61K 9/5123 (20130101) Original (OR) Class
A61K 9/5146 (20130101)
A61K 9/5192 (20130101)
A61K 47/24 (20130101)
A61K 47/26 (20130101)
A61K 47/34 (20130101)
A61K 47/42 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833495 Do et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Houston System (Houston, Texas)
ASSIGNEE(S) UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas)
INVENTOR(S) Loi Hung Do (Manvel, Texas);  Zhongzheng Cai (Houston, Texas);  Thi Tran (Houston, Texas);  Dawei Xiao (Houston, Texas)
ABSTRACT Phosphine phosphonate and phenoxyphosphine ligands bearing polyethylene glycol (PEG) chains are used as described herein to produce heterobimetallic catalysts. The ligands can be metallated selectively with palladium or nickel and secondary metal ions to provide well-defined heterobimetallic compounds. These heterobimetallic complexes exhibit accelerated reaction rates and greater thermal stability in olefin polymerization compared to other catalysts.
FILED Wednesday, March 22, 2023
APPL NO 18/124708
ART UNIT 1738 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/2243 (20130101) Original (OR) Class
B01J 31/2247 (20130101)
B01J 2531/0205 (20130101)
B01J 2531/0297 (20130101)
B01J 2531/824 (20130101)
B01J 2531/847 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 4/7014 (20130101)
C08F 10/02 (20130101)
C08F 2410/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833504 Lee et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  PIONEER HI-BRED INTERNATIONAL, INC. (Johnston, Iowa)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  PIONEER HI-BRED INTERNATIONAL, INC. (Johnston, Iowa)
INVENTOR(S) Abraham P. Lee (Irvine, California);  Michelle A. Digman (Irvine, California);  Dohyun Lee (Irvine, California);  Xuan Li (Irvine, California);  Ning Ma (Irvine, California);  Yue Yun (Johnston, Iowa)
ABSTRACT Methods and devices for single cell analysis using fluorescence lifetime imaging microscopy (FLIM) are disclosed. The methods utilize microfluidic devices which use traps to immobilize cells for FLIM analysis. The analysed cells may be sorted before or after imaging and may be plant, animal, or bacterial cells. Analysis of the FLIM data may use a phasor plot and may be used to identify a metabolic pattern of the single cells.
FILED Monday, April 13, 2020
APPL NO 16/847305
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 3/502761 (20130101) Original (OR) Class
B01L 2200/0647 (20130101)
B01L 2300/0627 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0854 (20130101)
B01L 2300/0858 (20130101)
B01L 2300/0864 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1003 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833684 Chu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Diligent Robotics, Inc. (Austin, Texas)
ASSIGNEE(S) Diligent Robotics, Inc. (Austin, Texas)
INVENTOR(S) Vivian Yaw-Wen Chu (Austin, Texas);  Shuai Li (Austin, Texas);  Forrest Green (Austin, Texas);  Peter Worsnop (Austin, Texas);  Andrea Lockerd Thomaz (Austin, Texas)
ABSTRACT Systems, apparatus, and methods are described for robotic learning and execution of skills. A robotic apparatus can include a memory, a processor, sensors, and one or more movable components (e.g., a manipulating element and/or a transport element). The processor is operatively coupled to the memory, the movable elements, and the sensors, and configured to obtain information of an environment, including one or more objects located within the environment. In some embodiments, the processor is configured to learn skills through demonstration, exploration, user inputs, etc. In some embodiments, the processor is configured to execute skills and/or arbitrate between different behaviors and/or actions. In some embodiments, the processor is configured to learn an environmental constraint. In some embodiments, the processor is configured to learn using a general model of a skill.
FILED Monday, March 01, 2021
APPL NO 17/188445
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/163 (20130101) Original (OR) Class
B25J 15/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833742 You et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Child Health and Human Development (NICHD)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Shangting You (La Jolla, California);  Shaochen Chen (San Diego, California)
ABSTRACT A method and system for microscale 3D printing achieve high-fidelity fabrication through the control of the light exposure time. A single pulse of light is used to initiate polymerization of a pre-polymer solution to minimize scattering-induced resolution deterioration. The printed object is fabricated in a layer-by-layer construction where each layer is formed through exposure to a single light pulse.
FILED Monday, June 28, 2021
APPL NO 17/360891
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/129 (20170801) Original (OR) Class
B29C 64/232 (20170801)
B29C 64/245 (20170801)
B29C 64/273 (20170801)
B29C 64/286 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834416 Goodson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Board of Trustees of Southern Illinois University (Carbondale, Illinois);  Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Board of Trustees of Southern Illinois University (Carbondale, Illinois);  Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Boyd M. Goodson (Carbondale, Illinois);  Eduard Y. Chekmenev (Troy, Michigan);  Bryce E. Kidd (Carbondale, Illinois);  Jamil A. Mashni (Carbondale, Illinois);  Miranda Limbach (Creal Springs, Illinois);  Yuqing Hou (Carbondale, Illinois);  Fan Shi (Houston, Texas)
ABSTRACT The present disclosure is directed to a cleavable agent for enhanced magnetic resonance generally corresponding to the formula Y-L-R, wherein Y represents a catalyst-binding moiety having at least one isotopically labeled heteroatom, L represents a cleavable bond, and R represents a hyperpolarized payload having at least one isotopically labeled carbon. Also disclosed herein is a method of cleaving the cleavable agent for enhanced magnetic resonance.
FILED Wednesday, November 27, 2019
APPL NO 16/698332
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/12 (20130101)
B01J 2531/827 (20130101)

Heterocyclic Compounds
C07D 213/46 (20130101)
C07D 213/63 (20130101)
C07D 233/60 (20130101) Original (OR) Class
C07D 241/12 (20130101)
C07D 401/06 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/6506 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/46 (20130101)
G01R 33/282 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834517 He et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) BRANDEIS UNIVERSITY (Waltham, Massachusetts)
ASSIGNEE(S) BRANDEIS UNIVERSITY (Waltham, Massachusetts)
INVENTOR(S) Hongjian He (Waltham, Massachusetts);  Bing Xu (Newton, Massachusetts)
ABSTRACT The present invention relates to a branched peptide that includes a first peptide chain and a second peptide chain having its C-terminal amino acid covalently linked to a sidechain of an amino acid residue of the first peptide chain, wherein the first peptide chain includes a plurality of aromatic amino acids and, optionally, an aromatic group linked to an amino terminus of the first peptide chain; and the second peptide chain includes a plurality of hydrophilic amino acids and an enzyme cleavage site. Pharmaceutical compositions containing the branched peptide and one or more therapeutic agents in an aqueous medium are disclosed, where the branched peptides form micelle structures in the aqueous medium. Methods of using the pharmaceutical composition to deliver therapeutic agents, and for treating various disease conditions are also described.
FILED Monday, November 29, 2021
APPL NO 17/537418
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)
A61P 35/00 (20180101)

Peptides
C07K 7/06 (20130101) Original (OR) Class
C07K 7/08 (20130101)
C07K 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11834689 Ptacin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) SYNTHORX, INC. (La Jolla, California);  THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California);  SYNTHORX, INC. (La Jolla, California)
INVENTOR(S) Jerod Ptacin (La Jolla, California);  Carolina Caffaro (La Jolla, California);  Hans Aerni (La Jolla, California);  Yorke Zhang (La Jolla, California);  Emil C. Fischer (La Jolla, California);  Aaron W. Feldman (La Jolla, California);  Vivian T. Dien (La Jolla, California);  Floyd E. Romesberg (La Jolla, California)
ABSTRACT Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
FILED Tuesday, March 09, 2021
APPL NO 17/196151
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/93 (20130101) Original (OR) Class
C12N 15/90 (20130101)
C12N 15/113 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 21/02 (20130101)

Enzymes
C12Y 601/01026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835497 Jones et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Activated Research Company, LLC (Eden Prairie, Minnesota)
ASSIGNEE(S) ACTIVATED RESEARCH COMPANY, LLC (Eden Prairie, Minnesota)
INVENTOR(S) Andrew Jones (Minneapolis, Minnesota);  Tommy Saunders (St. Louis Park, Minnesota);  Mike Hofflander (Edina, Minnesota)
ABSTRACT In the present system and method, a conduit from a LC device continuously transports solvent, buffers, and analytes to the inlet of a solvent removal and analyte conversion device which evaporates the solvents, leaving non-volatile analytes for detection. The device comprises a rotating disk. The liquid chromatograph device can be any device using liquid chromatography to separate molecules. The solvents in the LC effluent can include, but are not limited to, water, methanol, acetonitrile, tetrahydrofuran, and acetone. After removal of the volatile components, the non-volatile analytes are converted with a concentrated energy source so that they may be detectable.
FILED Wednesday, July 20, 2022
APPL NO 17/869244
ART UNIT 2853 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/38 (20130101)
G01N 30/64 (20130101) Original (OR) Class
G01N 2030/027 (20130101)
G01N 2030/347 (20130101)
G01N 2030/8417 (20130101)
G01N 2030/8447 (20130101)
G01N 2030/8494 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835500 Reed
FUNDED BY
National Science Foundation (NSF)
Office of The Director (OD)
Experimental Program to Stimulate Competitive Research (EPS)
APPLICANT(S) ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana)
ASSIGNEE(S) The Administrators of the Tulane Educational Fund (New Orleans, Louisiana)
INVENTOR(S) Wayne F. Reed (New Orleans, Louisiana)
ABSTRACT Disclosed herein is a device and method for changing the conditions of a solution flowing in a serial path. In particular, disclosed herein is a device that includes a chemical reactor, a first system, and a second system that are each serial to one another. Each of the first system and the second system include a mixing chamber, a solvent reservoir, a solvent pump, and one or more detectors. Also disclosed herein is a method for changing the condition of a solution that includes flowing a liquid sample in a path, serially mixing the sample with at least two discrete solvents while it flows through the path, and detecting the condition of the sample after it is mixed with each solvent.
FILED Tuesday, October 13, 2015
APPL NO 15/518658
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Separation
B01D 2313/08 (20130101)

Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 33/811 (20220101)
B01F 33/834 (20220101)
B01F 35/2132 (20220101)
B01F 35/2133 (20220101)
B01F 35/7176 (20220101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 4/00 (20130101)
B01J 19/0093 (20130101)
B01J 19/245 (20130101)
B01J 2219/00813 (20130101)
B01J 2219/00867 (20130101)
B01J 2219/00871 (20130101)
B01J 2219/00889 (20130101)
B01J 2219/00894 (20130101)
B01J 2219/00952 (20130101)
B01J 2219/00968 (20130101)
B01J 2219/00997 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 1/34 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/38 (20130101)
G01N 15/02 (20130101)
G01N 30/78 (20130101) Original (OR) Class
G01N 2015/0092 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835681 Lin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts);  PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts);  PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Zin Lin (Boston, Massachusetts);  Federico Capasso (Cambridge, Massachusetts);  Alejandro W. Rodriquez (Princeton, New Jersey);  Marko Loncar (Belmont, Massachusetts);  Benedikt Groever (Somerville, Massachusetts)
ABSTRACT A multi-layered lens comprises a plurality of metasurface layers. At least some layers of the plurality of metasurface layers include features that exhibit angular phase controls. The angular phases of the at least some layers cause an angular aberration correction or an angle convergence that focuses light onto a focal point regardless of angles of incidence.
FILED Tuesday, June 19, 2018
APPL NO 16/623378
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/005 (20130101) Original (OR) Class
G02B 3/0087 (20130101)
G02B 27/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835706 Gopinath et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, A Body Corporate (Denver, Colorado)
INVENTOR(S) Juliet T. Gopinath (Boulder, Colorado);  Emily A. Gibson (Boulder, Colorado);  Victor M. Bright (Boulder, Colorado);  Richard Weir (Longmont, Colorado);  Diego Restrepo (Littleton, Colorado);  Baris Ozbay (Denver, Colorado)
ABSTRACT The present disclosure relates optical imaging devices and methods useful in biological and medical imaging applications. In one embodiment, an optical imaging device includes a flexible lightguide having a first end and a second end, the output of the source of pulsed infrared radiation being optically coupled to the first end of the flexible lightguide; a lens assembly attached to and optically coupled to the second end of the flexible lightguide, the lens assembly comprising a variable-focus lens element, the a variable-focus lens element having a tunable focal length; and a photodetector coupled to the flexible lightguide to detect radiation propagating from the second end toward the first end of the flexible lightguide. The optical imaging devices and methods can be used in both confocal and multi-photon techniques.
FILED Monday, April 20, 2020
APPL NO 16/853512
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 3/14 (20130101)
G02B 6/06 (20130101)
G02B 21/006 (20130101)
G02B 21/0032 (20130101)
G02B 21/0076 (20130101)
G02B 23/26 (20130101)
G02B 23/243 (20130101) Original (OR) Class
G02B 23/2446 (20130101)
G02B 23/2469 (20130101)
G02B 26/005 (20130101)

Pictorial Communication, e.g Television
H04N 23/56 (20230101)
H04N 23/555 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835842 Cousin et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) KAPTEYN MURNANE LABORATORIES, INC. (Boulder, Colorado)
ASSIGNEE(S) Regents of the Univ of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) Seth Lucien Cousin (Boulder, Colorado);  Michael Tanksalvala (Longmont, Colorado);  Henry C Kapteyn (Boulder, Colorado)
ABSTRACT Apparatus and methods for improved HHG of ultrashort pulse laser beams. A HHG assembly includes a gas distribution block and a waveguide cartridge having a HHG hollow core waveguide. The waveguide cartridge is attached to the gas distribution block and may be removed and replaced, while the gas distribution block remains affixed within the apparatus. The gas distribution block is configured to maintain a pressure profile within the hollow core fiber. The system also includes two operating beam sensors and two actuatable mirrors. The operating beam sensors are fixed with respect to the HHG assembly. The system is aligned before operation by adjusting the actuatable mirrors to optimize a sample beam through the waveguide and recording the position of the beam on the operating beam sensors. In operation, the mirrors are actuated to maintain the same positions of the input beam on the operating beam sensors.
FILED Monday, April 13, 2020
APPL NO 17/603233
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 27/281 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/353 (20130101)
G02F 1/354 (20210101)
G02F 1/365 (20130101)
G02F 1/3503 (20210101) Original (OR) Class
G02F 1/3555 (20130101)
G02F 2201/02 (20130101)
G02F 2201/58 (20130101)
G02F 2203/07 (20130101)
G02F 2203/48 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836515 Hu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Research Foundation for The State University of New York (Binghamton, New York)
ASSIGNEE(S) The Research Foundation for The State University o (, None)
INVENTOR(S) Yaohui Hu (Binghamton, New York);  Kartik Gopalan (Vestal, New York)
ABSTRACT Standard nested virtualization allows a hypervisor to run other hypervisors as guests, i.e. a level-0 (L0) hypervisor can run multiple level-1 (L1) hypervisors, each of which can run multiple level-2 (L2) virtual machines (VMs), with each L2 VM is restricted to run on only one L1 hypervisor. Span provides a Multi-hypervisor VM in which a single VM can simultaneously run on multiple hypervisors, which permits a VM to benefit from different services provided by multiple hypervisors that co-exist on a single physical machine. Span allows (a) the memory footprint of the VM to be shared across two hypervisors, and (b) the responsibility for CPU and I/O scheduling to be distributed among the two hypervisors. Span VMs can achieve performance comparable to traditional (single-hypervisor) nested VMs for common benchmarks.
FILED Tuesday, May 11, 2021
APPL NO 17/316990
ART UNIT 2196 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/45558 (20130101) Original (OR) Class
G06F 2009/4557 (20130101)
G06F 2009/45579 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836852 Guan et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) Board of Trustees of the University of Illinois (Urban, Illinois)
INVENTOR(S) Junfeng Guan (Champaign, Illinois);  Seyedsohrab Madani (Champaign, Illinois);  Suraj S. Jog (Champaign, Illinois);  Haitham Al Hassanieh (Champaign, Illinois);  Saurabh Gupta (Champaign, Illinois)
ABSTRACT A method includes receiving data including a plurality of data items, each data item of the plurality of data items including a three-dimensional (3D) radar heat map of an object and a corresponding two-dimensional (2D) image of the object captured by a stereo camera, inputting the training dataset into a machine learning model including a neural network (NN) that generates, from the 3D radar heat map, a 2D depth map for the object and outputs a probability that the 2D depth map is the corresponding 2D image of the object, and training the machine learning model based on a training dataset to generate a trained machine learning model that iteratively learns to generate an updated 2D depth map that approximates the corresponding 2D image. The training dataset includes the plurality of data items, the 2D depth map and the probability.
FILED Thursday, December 17, 2020
APPL NO 17/124637
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/593 (20170101)
G06T 15/04 (20130101)
G06T 15/06 (20130101)
G06T 17/00 (20130101) Original (OR) Class
G06T 2207/10028 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101)
G06V 10/454 (20220101)
G06V 10/764 (20220101)
G06V 20/56 (20220101)
G06V 20/64 (20220101)
G06V 20/647 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837211 Salahuddin et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Sayeef Salahuddin (Walnut Creek, California);  Dominic E. Labanowski (Berkeley, California)
ABSTRACT An acoustically driven ferromagnetic resonance (ADFMR) device includes a piezoelectric element, a pair of transducers arranged to activate the piezoelectric element to generate an acoustic wave, a magnetostrictive element arranged to receive the acoustic wave, and a readout circuit to detect one of either a change in the magnetostrictive element or a change in the acoustic wave.
FILED Monday, December 11, 2017
APPL NO 16/464066
ART UNIT 2654 — Audio Signals
CURRENT CPC
Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/10 (20130101)
G01N 27/72 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/18 (20130101)
G01R 33/1284 (20130101)

Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/36 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837455 Cooks et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Zane Baird (West Lafayette, Indiana);  Pu Wei (West Lafayette, Indiana)
ABSTRACT The invention generally relates to sample analysis systems and methods of use thereof. In certain aspects, the invention provides a system for analyzing a sample that includes an ion generator configured to generate ions from a sample. The system additionally includes an ion separator configured to separate at or above atmospheric pressure the ions received from the ion generator without use of laminar flowing gas, and a detector that receives and detects the separated ions.
FILED Friday, June 03, 2022
APPL NO 17/831951
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/622 (20130101)
G01N 27/623 (20210101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0013 (20130101)
H01J 49/24 (20130101) Original (OR) Class
H01J 49/061 (20130101)
H01J 49/142 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11837873 Isobe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Hiroki Isobe (Cambridge, Massachusetts);  Qiong Ma (Allston, Massachusetts);  Liang Fu (Winchester, Massachusetts);  Nuh Gedik (Watertown, Massachusetts);  Suyang Xu (Allston, Massachusetts);  Pablo Jarillo-Herrero (Cambridge, Massachusetts)
ABSTRACT Rectification is a process that converts electromagnetic fields into direct current (DC). Such a process underlies a wide range of technologies, including wireless communication, wireless charging, energy harvesting, and infrared detection. Existing rectifiers are mostly based on semiconductor diodes, with limited applicability to small voltages or high frequency inputs. Here, we present an alternative approach to current rectification that uses the electronic properties of quantum crystals without semiconductor junctions. We identify a new mechanism for rectification from skew scattering due to the chirality of itinerant electrons in time-reversal-invariant but inversion-breaking materials. Our calculations reveal large, tunable rectification effects in graphene multilayers and transition metal dichalcogenides. These effects can be used in high-frequency rectifiers by rational material design and quantum wavefunction engineering.
FILED Friday, June 11, 2021
APPL NO 17/345078
ART UNIT 2839 — Electrical Circuits and Systems
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/001 (20200101) Original (OR) Class
H02J 50/27 (20160201)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/4208 (20130101)
H02M 7/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11838402 Salman et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Albany, New York)
INVENTOR(S) Emre Salman (Albany, New York);  Milutin Stanacevic (Albany, New York);  Yasha Karimi (Albany, New York);  Tutu Wan (Albany, New York);  Yuanfei Huang (Albany, New York)
ABSTRACT A processing unit and a method of operating a processing unit. In an embodiment, the processing unit comprises a SIMON block cipher for transforming plaintext data into encrypted data. A key expansion module generates and outputs one or more encryption keys; and the key expansion module includes a first series of adiabatic registers for holding key generation data values, and for using adiabatic switching to transmit the key generation data values through the first series of adiabatic registers. A round function module receives the plaintext data and the one or more encryption keys, encrypts the plaintext data to generate the encrypted data, and outputs the encrypted data; and the round function module includes a second series of adiabatic registers for holding encryption data, and for using adiabatic switching to transmit the encryption data through the second series of adiabatic registers.
FILED Friday, March 13, 2020
APPL NO 17/438662
ART UNIT 2495 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0618 (20130101)
H04L 9/0625 (20130101) Original (OR) Class
H04L 9/0819 (20130101)
H04L 2209/24 (20130101)
H04L 2209/805 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11832749 Tartal et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) William Albert Tartal (Baltimore, Maryland);  Joram Shenhar (Fairfax, Virginia);  Joel Locknauth Dewnandan (Bladensburg, Maryland)
ABSTRACT A lockout device for an opening of a collection box, such as a postal collection box. The lockout device can include a cover sized to block the opening to prevent access to the contents of the collection box through the opening. In one example, the cover can be assembled over the opening and a locking pin can be inserted through apertures in the lateral sides of the opening walls and lateral sides of the cover. The locking pin can be lock in place using a lock and lock guard. In another example, the cover includes an internal extension assembly with clamping mechanisms that can engage with the lateral sides of the opening.
FILED Wednesday, September 29, 2021
APPL NO 17/449422
ART UNIT 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Household or Table Equipment
A47G 29/126 (20130101) Original (OR) Class
A47G 29/1207 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833547 Bombaugh et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Scott R. Bombaugh (Burke, Virginia);  Thomas J. Foti (Annandale, Virginia);  David E. Loyd (Stafford, Virginia);  Sarvang D. Shah (Fairfax, Virginia)
ABSTRACT Embodiments of a system and method for sorting and delivering articles in a processing facility. Delivery endpoints are divided and grouped into stop groups. A first sorter sorts items according to stop group and outputs the items to trays. The output trays from the first sorter are loaded to a second sorter. The second sorter sorts items for each stop group into trays based on carrier route segments. A manifest is created that comprises a list of the items in a tray. A mobile computing device alerts a delivery carrier when there is an item that needs to be delivered.
FILED Tuesday, May 24, 2022
APPL NO 17/664846
ART UNIT 3653 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/00 (20130101)
B07C 3/005 (20130101) Original (OR) Class
B07C 3/14 (20130101)
B07C 2301/0041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11833548 Bombaugh
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Scott R. Bombaugh (Burke, Virginia)
ABSTRACT Systems and methods for sorting items for delivery to delivery points, using delivery point compression. Items can be sorted and sequenced for delivery by a sorting machine having a finite number of sorting destinations. For routes having more delivery points than the number of sorting destinations, delivery point compression allows sorting destination assignments that eliminate delivery points not likely to receive any items. Sorting destination assignments can be performed by a processor of the sorting machine based on expected item information and delivery point item frequency scores.
FILED Friday, December 02, 2022
APPL NO 18/061404
ART UNIT 3653 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/006 (20130101) Original (OR) Class
B07C 3/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836668 Bornitz et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Carrie Ann Bornitz (Sioux Falls, South Dakota);  Robert E. Dixon, Jr. (Haymarket, Virginia);  Ryan M. Luckay (Vienna, Virginia)
ABSTRACT Systems and methods of creating, managing, and distributing supplemental content associated with items in a distribution network. A physical delivery item can be imaged and associated with additional content generated or associated with the sender of the physical delivery item.
FILED Friday, July 02, 2021
APPL NO 17/366807
ART UNIT 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0833 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836745 Dearing et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Stephen M. Dearing (Herndon, Virginia);  Kuldip K. Goyal (Alexandria, Virginia);  Gary C. Reblin (Falls Church, Virginia);  Margaret L. Choiniere (Gainesville, Virginia)
ABSTRACT Systems, methods and apparatus are disclosed for providing content associated with an information item on a distribution item using a computing device. In one aspect a method includes identifying an image of an information item on a distribution item. The method further includes processing, in a processor the image, to generate a data item determined by the information item. The method further includes decoding the data item to determine a set of attributes of the distribution item. The method further includes retrieving content associated with the distribution item using at least one of the attributes in the set of attributes. The method further includes delivering content associated with the distribution item.
FILED Friday, July 22, 2022
APPL NO 17/814467
ART UNIT 3685 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/18 (20130101)
B07C 2301/0066 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 30/02 (20130101) Original (OR) Class
G06Q 30/0601 (20130101)
G06Q 50/32 (20130101)
G06Q 50/184 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11833684 Chu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Diligent Robotics, Inc. (Austin, Texas)
ASSIGNEE(S) Diligent Robotics, Inc. (Austin, Texas)
INVENTOR(S) Vivian Yaw-Wen Chu (Austin, Texas);  Shuai Li (Austin, Texas);  Forrest Green (Austin, Texas);  Peter Worsnop (Austin, Texas);  Andrea Lockerd Thomaz (Austin, Texas)
ABSTRACT Systems, apparatus, and methods are described for robotic learning and execution of skills. A robotic apparatus can include a memory, a processor, sensors, and one or more movable components (e.g., a manipulating element and/or a transport element). The processor is operatively coupled to the memory, the movable elements, and the sensors, and configured to obtain information of an environment, including one or more objects located within the environment. In some embodiments, the processor is configured to learn skills through demonstration, exploration, user inputs, etc. In some embodiments, the processor is configured to execute skills and/or arbitrate between different behaviors and/or actions. In some embodiments, the processor is configured to learn an environmental constraint. In some embodiments, the processor is configured to learn using a general model of a skill.
FILED Monday, March 01, 2021
APPL NO 17/188445
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/163 (20130101) Original (OR) Class
B25J 15/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836857 Young et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Transportation (USDOT)
Federal Highway Administration (FHWA)
National Highway Traffic Safety Administration (NHTSA)
APPLICANT(S) TRX Systems, Inc. (Greenbelt, Maryland)
ASSIGNEE(S) TRX Systems, Inc. (Greenbelt, Maryland)
INVENTOR(S) Travis Young (Rockville, Maryland);  Daniel Hakim (Silver Spring, Maryland);  Daniel Franchy (Catonsville, Maryland);  Jared Napora (Severn, Maryland);  John Karvounis (Bowie, Maryland);  Jonathan Fetter Degges (Washington, District of Columbia);  Tim Wang (Germantown, Maryland);  Benjamin Funk (Hanover, Maryland);  Carole Teolis (Glendale, Maryland);  Carol Politi (Bethesda, Maryland);  Stuart Woodbury (Ellicott City, Maryland)
ABSTRACT Systems, methods and instructions for creating building models of physical structures is disclosed. The building model may be a collection of floors defined by outlines containing regions that may be offset relative to a main region, and a collection of connectors. Connectors may have connection points for tracking, routing and sizing. Connectors may indicate elevation changes through georeferenced structural features. Signal elements may also be features that provide corrections when tracking. Feature descriptors are data that describes the structural configuration and signal elements enabling them to be matched to previously collected data in a database. User interface elements assist a user of a tracking device in collecting floor information, structural features and signal features and validating certain collected information based on previously known information. The height of floors may also be inferred based on sensor data from the tracking device.
FILED Wednesday, August 03, 2022
APPL NO 17/880530
ART UNIT 2617 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3867 (20200801)

Electric Digital Data Processing
G06F 30/13 (20200101)

Image Data Processing or Generation, in General
G06T 17/05 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11836918 Wick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) CAMERAD TECHNOLOGIES (Decatur, Georgia)
ASSIGNEE(S) CAMERAD TECHNOLOGIES (Decatur, Georgia)
INVENTOR(S) Carson A. Wick (Decatur, Georgia);  Srini Tridandapani (Decatur, Georgia)
ABSTRACT A method for identifying a misidentified study can utilize a set of photographs captured at substantially the same time as a corresponding set of medical images. The method can include determining similarities between the photographs through machine learning models and determining that a misidentified study exists when the similarity between the photographs fails to satisfy a threshold similarity.
FILED Friday, September 09, 2022
APPL NO 17/942026
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11832601 Metcalf et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Eye Institute (NEI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Child Health and Human Development (NICHD)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) VANDERBILT UNIVERSITY (Nashville, Tennessee);  YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee);  YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Jason Metcalf (Dexter, Michigan);  Seth R. Bordenstein (Nashville, Tennessee);  Daniel Lepage (Centertown, Missouri);  Sarah Bordenstein (Nashville, Tennessee);  Mark Hochstrasser (Hamden, Connecticut);  John F. Beckmann (New Haven, Connecticut);  Judith Ronau (Hamden, Connecticut)
ABSTRACT The disclosure relates to genetically modified bacteria, genetically modified arthropods, and methods for controlling and/or reducing arthropod populations.
FILED Friday, June 09, 2017
APPL NO 16/307982
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0337 (20130101) Original (OR) Class
A01K 67/0339 (20130101)
A01K 2217/052 (20130101)
A01K 2217/206 (20130101)
A01K 2227/706 (20130101)
A01K 2267/02 (20130101)

Peptides
C07K 14/195 (20130101)
C07K 2319/21 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/205 (20210501)
C12N 9/22 (20130101)
C12N 9/6472 (20130101)
C12N 15/87 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/01 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 11836857 Young et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Department of Transportation (USDOT)
Federal Highway Administration (FHWA)
National Highway Traffic Safety Administration (NHTSA)
APPLICANT(S) TRX Systems, Inc. (Greenbelt, Maryland)
ASSIGNEE(S) TRX Systems, Inc. (Greenbelt, Maryland)
INVENTOR(S) Travis Young (Rockville, Maryland);  Daniel Hakim (Silver Spring, Maryland);  Daniel Franchy (Catonsville, Maryland);  Jared Napora (Severn, Maryland);  John Karvounis (Bowie, Maryland);  Jonathan Fetter Degges (Washington, District of Columbia);  Tim Wang (Germantown, Maryland);  Benjamin Funk (Hanover, Maryland);  Carole Teolis (Glendale, Maryland);  Carol Politi (Bethesda, Maryland);  Stuart Woodbury (Ellicott City, Maryland)
ABSTRACT Systems, methods and instructions for creating building models of physical structures is disclosed. The building model may be a collection of floors defined by outlines containing regions that may be offset relative to a main region, and a collection of connectors. Connectors may have connection points for tracking, routing and sizing. Connectors may indicate elevation changes through georeferenced structural features. Signal elements may also be features that provide corrections when tracking. Feature descriptors are data that describes the structural configuration and signal elements enabling them to be matched to previously collected data in a database. User interface elements assist a user of a tracking device in collecting floor information, structural features and signal features and validating certain collected information based on previously known information. The height of floors may also be inferred based on sensor data from the tracking device.
FILED Wednesday, August 03, 2022
APPL NO 17/880530
ART UNIT 2617 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3867 (20200801)

Electric Digital Data Processing
G06F 30/13 (20200101)

Image Data Processing or Generation, in General
G06T 17/05 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11836611 Yu et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Hong Yu (Shrewsbury, Massachusetts);  Tsendsuren Munkhdalai (Worcester, Massachusetts)
ABSTRACT Classification of an input task data set by meta level continual learning includes analyzing first and second training data sets in a task space to generate first and second meta weights and a slow weight value, and comparing an input task data set to the slow weight to generate a fast weight. The first and second meta weights are parameterized with the fast weight value to update the slow weight value, whereby a value is associated with the input task data set, thereby classifying the input task data set by meta level continual learning.
FILED Tuesday, July 24, 2018
APPL NO 16/044108
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 3/08 (20130101) Original (OR) Class
G06N 3/044 (20230101)
G06N 3/045 (20230101)
G06N 3/047 (20230101)
G06N 3/048 (20230101)
G06N 3/063 (20130101)
G06N 3/084 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11832871 Farritor et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Telemedicine and Advanced Technology Research Center (TATRC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Office of The Director (OD)
Experimental Program to Stimulate Competitive Research (EPS)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Shane Farritor (Lincoln, Nebraska);  Tom Frederick (Gretna, Nebraska);  Joe Bartels (Pittsburgh, Pennsylvania)
ABSTRACT The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices, and more specifically including end effectors that can be incorporated into such devices. Certain end effector embodiments include various vessel cautery devices that have rotational movement as well as cautery and cutting functions while maintaining a relatively compact structure. Other end effector embodiments include various end effector devices that have more than one end effector.
FILED Monday, June 21, 2021
APPL NO 17/352817
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/1445 (20130101) Original (OR) Class
A61B 34/30 (20160201)
A61B 2018/0063 (20130101)
A61B 2018/00345 (20130101)
A61B 2018/00595 (20130101)
A61B 2018/1455 (20130101)
A61B 2034/301 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11835740 Starkovich et al.
FUNDED BY
APPLICANT(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
ASSIGNEE(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
INVENTOR(S) John A Starkovich (Redondo Beach, California);  Edward M. Silverman (Redondo Beach, California)
ABSTRACT A method using capillary force lamination (CFL) for manufacturing a high-performance optical absorber, includes: texturizing a base layer of the high-performance optical absorber, the base layer comprising one or more of a polymer film and a polymer coating; joining a surface layer of the high-performance optical absorber to the base layer, the surface layer comprising a non-woven carbon nanotube (CNT) sheet; wetting the joined surface layer and base layer with a solvent; drying the joined surface layer and base layer; and treating the resulting base layer with plasma, creating the high-performance optical absorber.
FILED Thursday, March 23, 2023
APPL NO 18/125204
ART UNIT 2872 — Optics
CURRENT CPC
Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/0074 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Optical Elements, Systems, or Apparatus
G02B 5/003 (20130101) Original (OR) Class
G02B 2207/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11835763 Knight et al.
FUNDED BY
APPLICANT(S) Mark William Knight (El Segundo, California);  Stephanie Roxane Sandor-Leahy (El Segundo, California);  Lakshminarayanan Ravi Narasimhan (Redondo Beach, California)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Mark William Knight (El Segundo, California);  Stephanie Roxane Sandor-Leahy (El Segundo, California);  Lakshminarayanan Ravi Narasimhan (Redondo Beach, California)
ABSTRACT A method of making a photonic integrated circuit (PIC) is provided. The method comprises depositing a functional resist material layer over a substrate, disposing and pressing a stamp with a plurality of nanopatterns into the functional resist material for a period of time, and removing the stamp from the functional resist material to provide nanofeatures that are inverted versions of the nanopatterns, wherein the nanofeatures form one or more optical elements.
FILED Friday, October 22, 2021
APPL NO 17/508030
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/136 (20130101) Original (OR) Class
G02B 2006/12038 (20130101)
G02B 2006/12061 (20130101)
G02B 2006/12176 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11838078 Robinson
FUNDED BY
APPLICANT(S) Rampart Communications, Inc. (Annapolis, Maryland)
ASSIGNEE(S) Rampart Communications, Inc. (Linthicum Heights, Maryland)
INVENTOR(S) Matthew Brandon Robinson (Crownsville, Maryland)
ABSTRACT An apparatus includes a first communication device with multiple antennas, operably coupled to a processor and configured to access a codebook of transformation matrices. The processor generates a set of symbols based on an incoming data, and applies a permutation to each of the symbols to produce a set of permuted symbols. The processor transforms each of the permuted symbols based on at least one primitive transformation matrix, to produce a set of transformed symbols. The processor applies, to each of the transformed symbols, a precode matrix selected from the codebook of transformation matrices to produce a set of precoded symbols. The codebook of transformation matrices is accessible to a second communication device. The processor sends a signal to cause transmission, to the second communication device, of multiple signals, each representing a precoded symbol from the set of precoded symbols, each of the signals transmitted using a unique antenna from the plurality of antennas.
FILED Tuesday, March 15, 2022
APPL NO 17/695703
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission
H04B 7/0456 (20130101) Original (OR) Class
H04B 7/0491 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11838397 Konigsburg
FUNDED BY
APPLICANT(S) Brian R. Konigsburg (Pasadena, Maryland)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Brian R. Konigsburg (Pasadena, Maryland)
ABSTRACT In an example, a synchronization signal can be transmitted to a plurality of synchronizers. The plurality of synchronizers can include a plurality of upstream synchronizers and a downstream synchronizer. Each synchronizer of the plurality of upstream synchronizers can be caused to count from a respective count value until a predetermined end count sequence value in response to receiving the synchronization signal. The respective count value stored at each synchronizer can be representative of a difference in time between a respective upstream synchronizer of the plurality of upstream synchronizers receiving the synchronization signal and the downstream synchronizer receiving the synchronization signal. A respective processing element of a plurality of processing elements can be caused to start a respective function or operation in response to a respective upstream synchronizer reaching the predetermined end count sequence value.
FILED Thursday, June 17, 2021
APPL NO 17/350758
ART UNIT 2465 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 7/0004 (20130101)
H04L 7/0016 (20130101) Original (OR) Class
H04L 7/0079 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, December 05, 2023.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20231205.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital