FedInvent™ Patents

Patent Details for Tuesday, December 26, 2023 

This page was updated on Wednesday, December 27, 2023 at 09:17 PM GMT

Department of Health and Human Services (HHS) 

US 11850029 Mehrotra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Sanjay Mehrotra (Winnetka, Illinois);  Ilya Mikhelson (Wilmette, Illinois);  Alan Varteres Sahakian (Northbrook, Illinois)
ABSTRACT Representative methods, apparatus and systems are disclosed for blood pressure and other vital sign monitoring using arterial applanation tonometry, including ambulatory blood pressure and other vital sign monitoring. A representative system comprises a wearable apparatus. The various embodiments measure blood pressure and other vital sign monitoring using a plurality of pressure sensors of a pressure sensor array, with one or more of the pressure sensors 140 applanating an artery, such as a radial artery. In a first embodiment, a pressure sensor signal is utilized which has the highest cross-coherence with the signals of its nearest pressure sensor neighbors of the pressure sensor array. In a second embodiment, Kalman filtering is utilized for the pressure sensor signals from the pressure sensor array.
FILED Monday, July 26, 2021
APPL NO 17/385216
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/02 (20130101)
A61B 5/02108 (20130101) Original (OR) Class
A61B 5/6824 (20130101)
A61B 2562/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850061 Kopperdahl et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) O.N.Diagnostics, LLC (Berkeley, California)
ASSIGNEE(S) O.N.Diagnostics, LLC (Berkeley, California)
INVENTOR(S) David L. Kopperdahl (Berkeley, California);  Paul Frederick Hoffmann (Oakland, California);  David Choen Lee (Berkeley, California);  Tony M. Keaveny (Berkeley, California)
ABSTRACT A system and method for the use of the results from a structural analysis of a patient's bone from a clinical scan, to be used clinically to manage patients in a widespread and consistent fashion.
FILED Monday, December 02, 2019
APPL NO 16/700574
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/4509 (20130101) Original (OR) Class
A61B 5/7246 (20130101)
A61B 6/032 (20130101)
A61B 6/463 (20130101)
A61B 6/482 (20130101)
A61B 6/505 (20130101)
A61B 6/5217 (20130101)
A61B 8/0875 (20130101)
A61B 8/5223 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 15/00 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850066 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Quan Zhang (Winchster, Massachusetts);  Yuanting Zhang (Hong Kong, China PRC)
ABSTRACT A system and method for measuring and monitoring blood pressure is provided. The system includes a wearable device and a tonometry device coupled to the wearable device. The Tonometry device is configured to compress a superficial temporal artery (STA] of a user. A sensor pad is attached to the wearable device adjacent the tonometry device. A blood pressure sensor is integrated within the sensor pad for continuous, unobtrusive blood pressure monitoring.
FILED Friday, October 31, 2014
APPL NO 15/032933
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0002 (20130101)
A61B 5/0022 (20130101)
A61B 5/022 (20130101)
A61B 5/026 (20130101)
A61B 5/33 (20210101)
A61B 5/0245 (20130101)
A61B 5/0261 (20130101)
A61B 5/742 (20130101)
A61B 5/02055 (20130101)
A61B 5/02108 (20130101)
A61B 5/02125 (20130101)
A61B 5/02416 (20130101)
A61B 5/6803 (20130101) Original (OR) Class
A61B 5/7278 (20130101)
A61B 5/7282 (20130101)
A61B 2560/0223 (20130101)
A61B 2562/04 (20130101)
A61B 2562/12 (20130101)
A61B 2562/046 (20130101)
A61B 2562/164 (20130101)
A61B 2562/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850081 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Ge Wang (Loudonville, New York);  Wenxiang Cong (Albany, New York)
ABSTRACT A machine-learning-based monochromatic CT image reconstruction method is described for quantitative CT imaging. The neural network is configured to learn a nonlinear mapping function from a training data set to map a CT image, which is reconstructed from a single spectral current-integrating projection data set, to monochromatic projections at a pre-specified energy level, realizing monochromatic CT imaging and overcoming beam hardening. An apparatus, method and/or system are configured to determine, by a trained artificial neural network (ANN), a monochromatic projection data set based, at least in part, on a measured CT image. The measured CT image may be reconstructed based, at least in part, on measured projection data. The measured projection data may be polychromatic. The apparatus, method and/or system may be further configured to reconstruct a monochromatic CT image based, at least in part, on the monochromatic projection data set.
FILED Monday, August 30, 2021
APPL NO 17/460470
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/032 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)

Image Data Processing or Generation, in General
G06T 11/006 (20130101)
G06T 2207/10081 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)

Image or Video Recognition or Understanding
G06V 10/60 (20220101)
G06V 10/764 (20220101)
G06V 10/774 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850141 El-Kurdi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Mohammed S. El-Kurdi (Pittsburgh, Pennsylvania);  William R. Wagner (Gibsonia, Pennsylvania);  David A. Vorp (Pittsburgh, Pennsylvania);  John J. Stankus (Campbell, California);  Lorenzo Soletti (Pittsburgh, Pennsylvania);  Jonathan McGrath (Middletown, Rhode Island);  Yi Hong (Pittsburgh, Pennsylvania);  J Christopher Flaherty (Middletown, Rhode Island)
ABSTRACT A tubular tissue graft device is provided comprising a tubular member and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.
FILED Friday, September 20, 2019
APPL NO 16/577579
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/04 (20130101)
A61F 2/06 (20130101) Original (OR) Class
A61F 2/062 (20130101)
A61F 2002/072 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850216 Rashidian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts);  The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Mohammad Rashidian (Cambridge, Massachusetts);  Hidde L. Ploegh (Boston, Massachusetts);  Ralph Weissleder (Peabody, Massachusetts);  Edmund J. Keliher (Topsfield, Massachusetts)
ABSTRACT The present invention, in some aspects, provides methods, reagents, compositions, and kits for the radiolabeling of proteins, for example, of proteins useful for positron emission tomography (PET) or single-photon emission computed tomography (SPECT) (e.g., for diagnostic and therapeutic applications), using sortase-mediated transpeptidation reactions. Some aspects of this invention provide methods for the conjugation of an agent, for example, a radioactive agent or molecule to diagnostic or therapeutic peptides or proteins. Compositions comprising sortagged, radiolabeled proteins as well as reagents for generating radiolabeled proteins are also provided. Kits comprising reagents useful for the generation of radiolabeled proteins are provided, as are precursor proteins that comprise a sortase recognition motif.
FILED Wednesday, January 08, 2020
APPL NO 16/737620
ART UNIT RD00 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/08 (20130101)
A61K 51/1096 (20130101) Original (OR) Class

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 5/02 (20130101)

Peptides
C07K 16/2845 (20130101)
C07K 2317/55 (20130101)
C07K 2317/569 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/52 (20130101)

Enzymes
C12Y 304/2207 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/60 (20130101)
G01N 2333/95 (20130101)
G01N 2800/52 (20130101)
G01N 2800/7028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850236 Tang et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida);  The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethseda, Maryland);  Florida State University Research Foundation, Inc. (Tallahassee, Florida);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Hengli Tang (Tallahassee, Florida);  Emily M. Lee (Tallahassee, Florida);  Wei Zheng (Rockville, Maryland);  Ruili Huang (Rockville, Maryland);  Miao Xu (Rockville, Maryland);  Wenwei Huang (Rockville, Maryland);  Khalida Shamim (Rockville, Maryland);  Guoli Ming (Philadelphia, Pennsylvania);  Hongjun Song (Philadelphia, Pennsylvania)
ABSTRACT The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections.
FILED Tuesday, June 28, 2022
APPL NO 17/809339
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/165 (20130101)
A61K 31/245 (20130101)
A61K 31/336 (20130101)
A61K 31/352 (20130101)
A61K 31/422 (20130101)
A61K 31/427 (20130101)
A61K 31/433 (20130101)
A61K 31/506 (20130101)
A61K 31/517 (20130101)
A61K 31/519 (20130101)
A61K 31/554 (20130101)
A61K 31/4162 (20130101)
A61K 31/4184 (20130101) Original (OR) Class
A61K 31/4535 (20130101)
A61K 31/4709 (20130101)
A61K 31/4741 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850247 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota);  Emory University (Atlanta, Georgia)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota);  EMORY UNIVERSITY (Atlanta, Georgia)
INVENTOR(S) Zhengqiang Wang (Minneapolis, Minnesota);  Stefanos G. Sarafianos (Atlanta, Georgia)
ABSTRACT The invention provides a compound of formula I, formula II, or formula III:
or a salt thereof, wherein R1-R10 have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as HIV-1 CA-targeting molecules and as antiviral agents.
FILED Monday, April 05, 2021
APPL NO 17/222433
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/167 (20130101)
A61K 31/405 (20130101)
A61K 31/495 (20130101)
A61K 31/513 (20130101)
A61K 31/517 (20130101) Original (OR) Class
A61K 31/4178 (20130101)
A61K 31/4184 (20130101)
A61K 31/4439 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)

Acyclic or Carbocyclic Compounds
C07C 233/88 (20130101)

Heterocyclic Compounds
C07D 209/34 (20130101)
C07D 235/02 (20130101)
C07D 239/54 (20130101)
C07D 239/96 (20130101)
C07D 241/08 (20130101)
C07D 401/12 (20130101)
C07D 403/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850256 Burke et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Martin D. Burke (Champaign, Illinois);  Katrina A. Muraglia (Champaign, Illinois)
ABSTRACT Provided herein are complexes comprising amphotericin B (AmB) or derivatives and sterols. Also provided herein are methods of treating cystic fibrosis using AmB or complexes comprising AmB or derivatives and sterols.
FILED Tuesday, June 01, 2021
APPL NO 17/335803
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/007 (20130101)
A61K 9/0019 (20130101)
A61K 9/0073 (20130101)
A61K 31/575 (20130101)
A61K 31/575 (20130101)
A61K 31/7048 (20130101) Original (OR) Class
A61K 31/7048 (20130101)
A61K 47/28 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 11/10 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 17/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850258 Karalkar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Nilesh B. Karalkar (Gainesville, Florida);  Steven A. Benner (Gainesville, Florida)
ASSIGNEE(S)
INVENTOR(S) Nilesh B. Karalkar (Gainesville, Florida);  Steven A. Benner (Gainesville, Florida)
ABSTRACT This invention claims ribonucleosides and their derivatives, including triphosphates, that have a 3′-ONH2 moiety instead of a 3′-OH moiety.
FILED Friday, May 29, 2020
APPL NO 16/887951
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/708 (20130101) Original (OR) Class
A61K 31/7068 (20130101)
A61K 31/7072 (20130101)
A61K 31/7076 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850263 Waller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Emory University (Atlanta, Georgia);  Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Edmund Waller (Atlanta, Georgia);  Susan Thomas (Atlanta, Georgia);  Rebecca Pankove (Atlanta, Georgia);  Sruthi Ravindranathan (Decatur, Georgia);  David Francis (Atlanta, Georgia)
ABSTRACT This disclosure relates to compositions comprising an antagonist of vasoactive intestinal polypeptide signaling coupled to a nanoparticle and methods of use related thereto. In certain embodiments, the nanoparticle is a poloxamer-stabilized polypropylene sulfide nanoparticle.
FILED Friday, November 09, 2018
APPL NO 16/763197
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 35/17 (20130101) Original (OR) Class
A61K 38/00 (20130101)
A61K 47/62 (20170801)
A61K 47/6935 (20170801)

Peptides
C07K 14/57563 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850266 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  The Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  The Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Richard T. Lee (Cambridge, Massachusetts);  Jessica Garbern (Brookline, Massachusetts);  Douglas A. Melton (Cambridge, Massachusetts);  Aharon Helman (Cambridge, Massachusetts)
ABSTRACT Disclosed herein are methods for generating mature cardiomyocytes and compositions including mature cardiomyocytes. Also disclosed herein are methods for enhancing maturation of quiescent cardiomyocytes and compositions including mature quiescent cardiomyocytes.
FILED Monday, June 08, 2020
APPL NO 17/616994
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/34 (20130101) Original (OR) Class
A61K 38/005 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850273 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Gong Chen (State College, Pennsylvania);  Gang-Yi Wu (State College, Pennsylvania);  Lei Zhang (State College, Pennsylvania);  Jiu-Chao Yin (State College, Pennsylvania);  Hana Yeh (State College, Pennsylvania);  Ning-Xin Ma (State College, Pennsylvania);  Grace Lee (State College, Pennsylvania)
ABSTRACT Provided are methods and compositions from reprogramming human glial cells into human neurons. The reprogramming is achieved using combinations of compounds that can modify signaling via Transforming growth factor beta (TGF-β), Bone morphogenetic protein (BMP), glycogen synthase kinase 3 (GSK-3), and γ-secretase/Notch pathways. The reprogramming is demonstrated using groups of three or four compounds that are chosen from the group thiazovivin, LDN193189, SB431542, TTNPB, CHIR99021, DAPT, VPA, SAG; purmorphamine. Reprogramming is demonstrated using the group of LDN193189/CHIR99021/DAPT, the group of B431542/CHIR99021/DAPT, the group of LDN193189/DAPT/SB431542, the group of LDN193189/CHIR99021/SB431542, a three drug combination of SB431542/CHIR99021/DAPT. Reprogramming using functional analogs of the compounds is also provided, as are pharmaceutical formulations that contain the drug combinations.
FILED Monday, August 09, 2021
APPL NO 17/397927
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 31/506 (20130101)
A61K 31/506 (20130101)
A61K 31/519 (20130101)
A61K 31/519 (20130101)
A61K 31/4439 (20130101)
A61K 31/4439 (20130101)
A61K 38/05 (20130101) Original (OR) Class
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0619 (20130101)
C12N 2501/15 (20130101)
C12N 2501/155 (20130101)
C12N 2501/727 (20130101)
C12N 2501/998 (20130101)
C12N 2501/999 (20130101)
C12N 2506/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850281 Wu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Yuntao Wu (Manassas, Virginia)
ASSIGNEE(S) George Mason Research Foundation, Inc. (Fairfax, Virginia)
INVENTOR(S) Yuntao Wu (Manassas, Virginia)
ABSTRACT Persistence of HIV in anatomic sanctuary sites such as the brain prevents viral eradication. Although combination antiretroviral therapy (cART) inhibits viral replication to undetectable level by standard clinical assay, it does not selectively eliminate virus reservoirs. To target HIV reservoirs, the present inventor developed an HIV Rev-dependent lentiviral vector carrying a series of therapeutic genes, such as diphtheria toxin, anthrolysin O from Bacillus anthracis, human TRAF6, or the herpes simplex 1 virus thymidine kinase gene (HSV-tk). The present disclosure provides the Rev-dependent vectors for targeting viral reservoir in a SIV/rhesus macaque model. SIV-infected rhesus macaques were first treated with cART for over 6 months starting 12 weeks post infection, followed by injections with viral particles assembled from a SIV Rev-dependent vector carrying HSV-tk. Following particle injection, animals were further treated briefly (two weeks) with ganciclovir (GCV), which induces the killing of SIV+, HSV-tk expressing cells. cART was terminated following the GCV treatment, and there was observed a partial control of viral rebound over a period of 4 months after cART cessation. The animal was further treated with additional Rev-dependent vector particles, and viral load was diminished to the undetectable level for over 1 year in the absence of any treatment. These results suggest that the Rev-dependent vector, with or without a functional gene, has the potential to diminish viral reservoirs in vivo and can offer a cure of functional cure of HIV/SIV infection.
FILED Tuesday, October 23, 2018
APPL NO 16/758577
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/02 (20130101) Original (OR) Class
A61K 39/42 (20130101)
A61K 45/06 (20130101)
A61K 2039/5256 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2710/16634 (20130101)
C12N 2710/16671 (20130101)
C12N 2740/15034 (20130101)
C12N 2740/15043 (20130101)
C12N 2740/15071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850284 Quijano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Elias Quijano (Durham, Connecticut);  Peter Glazer (Guilford, Connecticut)
ABSTRACT Compositions and methods of use thereof for delivering nucleic acid cargo into cells are provided. The compositions typically include (a) a 3E10 monoclonal antibody or an antigen binding, cell-penetrating fragment thereof; a monovalent, divalent, or multivalent single chain variable fragment (scFv); or a diabody; or humanized form or variant thereof, and (b) a nucleic acid cargo including, for example, a nucleic acid encoding a polypeptide, a functional nucleic acid, a nucleic acid encoding a functional nucleic acid, or a combination thereof. Elements (a) and (b) are typically non-covalently linked to form a complex.
FILED Tuesday, August 30, 2022
APPL NO 17/823494
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/549 (20170801) Original (OR) Class
A61K 47/6807 (20170801)
A61K 47/6851 (20170801)
A61K 48/00 (20130101)
A61K 48/005 (20130101)
A61K 48/0025 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/52 (20130101)
C07K 14/4747 (20130101)
C07K 16/44 (20130101)
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/77 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/87 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 15/1135 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2310/3181 (20130101)
C12N 2310/3513 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850289 Jaskula-Ranga et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Vinod Jaskula-Ranga (Cambridge, Massachusetts);  Donald Zack (Baltimore, Maryland)
ABSTRACT The presently disclosed subject matter provides compositions and methods for the expression of CRISPR guide RNAs using the H1 promoter. In particular, compositions and methods are provided for the use of the H1 promoter to express CRISPR guide RNA (gRNA) with altered specificity of the 5′ nucleotide, as well as use of the H1 promoter sequence as a bidirectional promoter to express Cas9 nuclease and the gRNA simultaneously. Compositions and methods are also provided for the expression and regulation of gRNA expression in vivo through the use of RNA ribozymes and regulatable aptazymes.
FILED Friday, April 17, 2020
APPL NO 16/851636
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/0066 (20130101) Original (OR) Class

Peptides
C07K 2319/10 (20130101)
C07K 2319/60 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101)
C12N 15/85 (20130101)
C12N 15/86 (20130101)
C12N 15/111 (20130101)
C12N 15/907 (20130101)
C12N 15/1138 (20130101)
C12N 15/8616 (20130101)
C12N 2310/10 (20130101)
C12N 2310/20 (20170501)
C12N 2330/51 (20130101)
C12N 2750/14133 (20130101)
C12N 2750/14143 (20130101)
C12N 2830/85 (20130101)
C12N 2830/205 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850309 Farokhzad et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
INVENTOR(S) Omid Farokhzad (Waban, Massachusetts);  Jun Wu (Boston, Massachusetts);  Lili Zhao (Boston, Massachusetts)
ABSTRACT Cationic polymers are provided for delivering anionic active agents, preferably in the form or nanoparticles and other nanostructures. The polymer can be a polycation homopolymer or a copolymer containing a polycation block. The polycations and polycation containing polymers can contain dicarboxylic acid ester units and units of (α-amino acid)-α,ω-alkylene diester units. The nanoparticles can contain high loadings of anionic active agents, with sustained release of the active agents. Methods of making the polycations and polycation containing polymers are provided. Methods of making the nanoparticles and formulating them for administration to an individual in need thereof are also provided.
FILED Monday, August 24, 2020
APPL NO 17/001237
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/5073 (20130101)
A61K 9/5078 (20130101)
A61K 9/5153 (20130101) Original (OR) Class
A61K 9/5192 (20130101)
A61K 38/28 (20130101)
A61K 38/38 (20130101)
A61K 38/385 (20130101)
A61K 47/60 (20170801)
A61K 47/593 (20170801)
A61K 47/645 (20170801)
A61K 47/6931 (20170801)
A61K 47/6937 (20170801)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 81/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850427 Rezai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) West Virginia University Board of Governors on behalf of West Virginia University (Morgantown, West Virginia)
ASSIGNEE(S) WEST VIRGINIA UNIVERSITY BOARD OF GOVERNORS ON BEHALF OF WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia)
INVENTOR(S) Ali Rezai (Morgantown, West Virginia);  Victor Finomore (Morgantown, West Virginia);  James Mahoney (Morgantown, West Virginia)
ABSTRACT Methods of improving addiction in a patient in need thereof are provided. Methods include exposing the patient to drug related cues and measuring the patient's craving levels or physiological levels during or after cue exposure to determine the patient's status or condition. Such a determination can indicate whether the patient is at risk of engaging in the addictive activity and can guide therapeutic intervention.
FILED Wednesday, December 02, 2020
APPL NO 17/110174
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0534 (20130101)
A61N 1/36089 (20130101) Original (OR) Class
A61N 2/002 (20130101)
A61N 2/006 (20130101)
A61N 7/00 (20130101)
A61N 2007/0026 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101)
G16H 20/70 (20180101)
G16H 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850589 Italiano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  Vilnius University (Vilnius, Lithuania)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc., Boston, MA; (Cambridge, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts);  Vilnius University (Vilnius, Lithuania)
INVENTOR(S) Joseph Italiano (Chestnut Hill, Massachusetts);  Linas Mazutis (Boston, Massachusetts);  Jonathan N. Thon (Cambridge, Massachusetts);  David A. Weitz (Boston, Massachusetts)
ABSTRACT A system and method are provided for harvesting target biological substances. The system includes a substrate and a first and second channel formed in the substrate. The channels longitudinally extending substantially parallel to each other. A series of gaps extend from the first channel to the second channel to create a fluid communication path passing between a series of columns with the columns being longitudinally separated by a predetermined separation distance. The system also includes a first source configured to selectively introduce into the first channel a first biological composition at a first channel flow rate and a second source configured to selectively introduce into the second channel a second biological composition at a second channel flow rate. The sources are configured to create a differential between the first and second channel flow rates to generate physiological shear rates along the second channel that are bounded within a predetermined range.
FILED Friday, June 24, 2022
APPL NO 17/848523
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502746 (20130101)
B01L 3/502753 (20130101) Original (OR) Class
B01L 3/502776 (20130101)
B01L 2200/0647 (20130101)
B01L 2200/0668 (20130101)
B01L 2300/0681 (20130101)
B01L 2300/0816 (20130101)
B01L 2400/086 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101)
C12M 23/20 (20130101)
C12M 25/02 (20130101)
C12M 29/04 (20130101)
C12M 29/10 (20130101)
C12M 29/20 (20130101)
C12M 41/36 (20130101)
C12M 41/40 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/86 (20130101)
G01N 33/491 (20130101)
G01N 2800/222 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 436/25375 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851391 Garneau-Tsodikova et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Prostate Cancer Research Program (USAMRMCPCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Sylvie Garneau-Tsodikova (Lexington, Kentucky);  David S. Watt (Lexington, Kentucky);  Nishad Thamban Chandrika (Lexington, Kentucky)
ABSTRACT An antifungal composition and a method of treating a systemic fungal infection are provided herein. The antifungal composition includes a diaryl bishydrazone. The method includes administering a therapeutically effective amount of the diaryl bishydrazone to a subject in need thereof.
FILED Wednesday, July 17, 2019
APPL NO 16/514276
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/10 (20180101)

Acyclic or Carbocyclic Compounds
C07C 243/10 (20130101) Original (OR) Class
C07C 277/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851406 Lindsley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Craig W. Lindsley (Brentwood, Tennessee);  P. Jeffrey Conn (Nashville, Tennessee);  Darren W. Engers (Brentwood, Tennessee);  Julie L. Engers (Brentwood, Tennessee);  Aaron M. Bender (Spring Hill, Tennessee);  Madeline Long (Nashville, Tennessee)
ABSTRACT Described are positive allosteric modulators of muscarinic acetylcholine receptor M1 (mAChR M1), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating neurological disorders, psychiatric disorders, or a combination thereof.
FILED Thursday, June 13, 2019
APPL NO 17/251649
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 401/14 (20130101) Original (OR) Class
C07D 405/14 (20130101)
C07D 413/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851407 Ravert et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSTY (Baltimore, Maryland)
INVENTOR(S) Hayden T. Ravert (Bel Air, Maryland);  Daniel P. Holt (Severna Park, Maryland);  Ying Chen (Lutherville-Timonium, Maryland);  Ronnie C. Mease (Fairfax, Virginia);  Hong Fan (Timonium, Maryland);  Martin G. Pomper (Baltimore, Maryland);  Robert F. Dannals (Sparks, Maryland)
ABSTRACT Methods, and related compositions, for the improved synthesis of [18F]DCFPyL are disclosed. Also provided are methods, and related compositions, for the use of [18F]DCFPyL so produced.
FILED Tuesday, March 09, 2021
APPL NO 17/195895
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/0455 (20130101)
A61K 51/0497 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/002 (20130101)

Heterocyclic Compounds
C07D 213/42 (20130101) Original (OR) Class
C07D 213/82 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851427 Landry et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Donald W. Landry (New York, New York);  Shixian Deng (White Plains, New York);  Ottavio Arancio (New York, New York);  Jole Fiorito (Floral Park, New York);  Andrew Wasmuth (Brooklyn, New York)
ABSTRACT The invention provides for novel benzonaphthyridine derivatives and compositions comprising novel benzonaphthyridine derivatives. In some embodiments, the compounds are phosphodiesterase inhibitors. The invention further provides for methods for inhibition of phosphodiesterase comprising contacting phosphodiesterase with novel benzonaphthyridine derivatives or compositions comprising novel benzonaphthyridine derivatives. The invention further provides for methods for treatment of neurodegenerative diseases, increasing memory or long term potentiation with novel benzonaphthyridine derivatives or compositions comprising novel benzonaphthyridine derivatives. In some embodiments, the phosphodiesterase is PDE5.
FILED Wednesday, December 30, 2020
APPL NO 17/137665
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 471/04 (20130101) Original (OR) Class
C07D 471/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851441 Ghosh
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Arun K. Ghosh (West Lafayette, Indiana)
ABSTRACT Embodiments provide, among other compounds, a family of compounds that can be used as therapeutic anti-cancer agents, methods for using such compounds to treat cancer, and methods of making such compounds.
FILED Monday, November 09, 2020
APPL NO 17/092829
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/35 (20130101)
A61K 31/351 (20130101)
A61K 31/357 (20130101)
A61K 31/695 (20130101)
A61K 31/4025 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 309/14 (20130101)
C07D 493/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851458 Peoples et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) NovoBiotic Pharmaceuticals, LLC (Cambridge, Massachusetts)
ASSIGNEE(S) NovoBiotic Pharmaceuticals, LLC (Cambridge, Massachusetts)
INVENTOR(S) Aaron J. Peoples (Somerville, Massachusetts);  Dallas Hughes (Bolton, Massachusetts);  Losee Lucy Ling (Arlington, Massachusetts);  William Millett (Worcester, Massachusetts);  Anthony Nitti (Lexington, Massachusetts);  Amy Spoering (Waltham, Massachusetts);  Victoria Alexandra Steadman (Ongar, United Kingdom);  Jean-Yves Christophe Chiva (Ongar, United Kingdom);  Linos Lazarides (Ongar, United Kingdom);  Michael Kenyon Jones (Ongar, United Kingdom);  Karine Gaelle Poullennec (Ongar, United Kingdom);  Kim Lewis (Newton, Massachusetts);  Slava Epstein (Dedham, Massachusetts)
ABSTRACT The present invention relates generally to novel depsipeptides, to methods for the preparation of these novel depsipeptides, to pharmaceutical compositions comprising the novel depsipeptides; and to methods of using the novel depsipeptides to treat or inhibit various disorders.
FILED Wednesday, October 13, 2021
APPL NO 17/500761
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/15 (20130101)

Peptides
C07K 7/56 (20130101) Original (OR) Class
C07K 11/02 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/205 (20210501)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 17/14 (20130101)
C12P 21/02 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/01 (20210501)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851462 Kar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of South Carolina (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Amar N. Kar (Lexington, South Carolina);  Pabitra Sahoo (West Columbia, South Carolina);  Jeffery Twiss (Columbia, South Carolina);  Sean McGill (Columbia, South Carolina)
ABSTRACT Testing peptides in in vitro models of neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, Frontotemporal dementia, Amyotrophic lateral sclerosis, to evaluate systems and methods of treatment therefore.
FILED Friday, May 22, 2020
APPL NO 16/881096
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)

Peptides
C07K 7/08 (20130101)
C07K 14/435 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851464 Hazra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Tapas Hazra (Galveston, Texas);  Sanjiv Sur (Galveston, Texas);  Ashok Chopra (Galveston, Texas)
ABSTRACT Certain embodiments are directed to NEIL2 compositions and method of using NEIL2 composition to treat subjects in need of such treatment.
FILED Monday, April 11, 2022
APPL NO 17/717313
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 11/00 (20180101)
A61P 31/04 (20180101)

Peptides
C07K 14/47 (20130101) Original (OR) Class
C07K 2319/01 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/85 (20130101)
C12N 2015/8518 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851478 Crowe, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) James E Crowe, Jr. (Nashville, Tennessee)
ABSTRACT The present disclosure is directed to antibodies binding to and neutralizing Chikungunya virus (CHIKV) and methods for use thereof.
FILED Friday, January 04, 2019
APPL NO 16/959760
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/1081 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851479 Burnham-Marusich
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) DX DISCOVERY INC. (Reno, Nevada)
ASSIGNEE(S) DXDISCOVERY, INC. (Reno, Nevada)
INVENTOR(S) Amanda Burnham-Marusich (Reno, Nevada)
ABSTRACT Compositions and methods for the detection and diagnosis of Bordetella pertussis are disclosed. Provided are antibodies, or antigen binding fragment thereof, specific for tracheal colonization factor A (TcfA). Also provided are compositions comprising an anti-TcfA antibody of the instant invention and a carrier; and methods for inhibiting, treating, and/or preventing pertussis and/or a B. pertussis infection in a subject in need thereof are provided, comprising administering an anti-TcfA antibody of the instant invention to the subject.
FILED Tuesday, June 18, 2019
APPL NO 17/058446
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/1225 (20130101) Original (OR) Class
C07K 2317/565 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54388 (20210801)
G01N 33/56911 (20130101)
G01N 2333/235 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851482 Panicker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Bioverativ USA Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Genzyme Corporation (Cambridge, Massachusetts)
INVENTOR(S) Sandip Panicker (South San Francisco, California);  Graham Parry (Cambridge, Massachusetts);  Karen Sue Christopherson (San Mateo, California);  Tony SangYoung Byun (Brisbane, California)
ABSTRACT The present disclosure provides anti-complement factor Bb antibodies, and compositions comprising the antibodies. The anti-Bb antibodies are useful for treating complement-mediated disorders. The present disclosure provides methods of treating complement-mediated disorders.
FILED Tuesday, January 19, 2021
APPL NO 17/151860
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 16/40 (20130101)
C07K 2317/24 (20130101)
C07K 2317/33 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/94 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851490 Kan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Lixin Kan (Chicago, Illinois);  John A. Kessler (Chicago, Illinois)
ABSTRACT Disclosed are methods and compositions for treating, inhibiting, and/or preventing heterotopic ossification in a subject in need thereof. Particularly disclosed are methods for treating, inhibiting, and/or preventing heterotopic ossification in a subject in need thereof by administering to the subject a therapeutic agent such as an immune checkpoint inhibitor and/or Fetuin-A or a variant thereof. Also disclosed are pharmaceutical compositions and pharmaceutical kits comprising an immune checkpoint inhibitor and/or Fetuin-A or a variant thereof for treating, inhibiting, and/or preventing heterotopic ossification in a subject in need thereof.
FILED Monday, August 17, 2020
APPL NO 16/995392
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/16 (20130101)
A61K 38/1741 (20130101)
A61K 39/395 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/00 (20180101)

Peptides
C07K 16/2818 (20130101) Original (OR) Class
C07K 16/2827 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851498 Dimitrov et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH (Bethesda, Maryland);  BIOMED VALLEY DISCOVERIES, INC. (Kansas City, Missouri)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  BioMed Valley Discoveries, Inc. (Kansas City, Missouri)
INVENTOR(S) Dimiter S. Dimitrov (Frederick, Maryland);  Zhongyu Zhu (Frederick, Maryland);  Bradley St. Croix (Frederick, Maryland);  Steven Seaman (Martinsburg, West Virginia);  Saurabh Saha (Wellesley Hills, Massachusetts);  Xiaoyan Michelle Zhang (Lexington, Massachusetts);  Gary A. DeCrescenzo (Parkville, Missouri);  Dean Welsch (Parkville, Missouri)
ABSTRACT Polypeptides and proteins that specifically bind to and immunologically recognize CD276 are disclosed. Chimeric antigen receptors (CARs), anti-CD276 binding moieties, nucleic acids, recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, and conjugates relating to the polypeptides and proteins are also disclosed. Methods of detecting the presence of (a) cancer or (b) tumor vasculature in a mammal and methods of (a) treating or preventing cancer or (b) reducing tumor vasculature in a mammal are also disclosed.
FILED Monday, March 09, 2020
APPL NO 16/812980
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39558 (20130101)
A61K 47/6803 (20170801)
A61K 47/6849 (20170801)
A61K 47/6851 (20170801)
A61K 2039/505 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/30 (20130101) Original (OR) Class
C07K 16/2827 (20130101)
C07K 2317/24 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57492 (20130101)
G01N 2333/70532 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851503 Chakrabarti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida);  THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (Norman, Oklahoma)
ASSIGNEE(S) UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida);  THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (Norman, Oklahoma)
INVENTOR(S) Debopam Chakrabarti (Winter Springs, Florida);  Robert H. Cichewicz (Norman, Oklahoma);  Shengxin Cai (Norman, Oklahoma);  Jin Woo Lee (Norman, Oklahoma);  Jennifer E. Collins (Osteen, Florida)
ABSTRACT Novel compositions and methods for the treatment and prevention of malaria are disclosed herein.
FILED Monday, January 24, 2022
APPL NO 17/582787
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 33/06 (20180101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851511 Scott et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Timothy F. Scott (Ann Arbor, Michigan);  Harry van der Laan (Ann Arbor, Michigan);  Megan A. Cole (Ann Arbor, Michigan);  Mark A. Burns (Ann Arbor, Michigan);  Martin P. De Beer (Ann Arbor, Michigan);  Zachary D. Pritchard (Ann Arbor, Michigan);  Avi Bregman (Ann Arbor, Michigan)
ABSTRACT Provided herein is technology relating to polymerization and producing polymers and particularly, but not exclusively, to methods, systems, and compositions for producing articles using three-dimensional printing and for improving control of polymerization using a polymerization photoinhibitor having fast back reaction kinetics such as hexaarylbiimidazole compounds and bridged hexaarylbiimidazole compounds.
FILED Wednesday, October 13, 2021
APPL NO 17/500151
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 2/50 (20130101) Original (OR) Class
C08F 4/04 (20130101)
C08F 4/40 (20130101)
C08F 222/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851543 Bulger et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California)
ASSIGNEE(S) XEROX CORPORATION (Norwalk, Connecticut)
INVENTOR(S) Eli Bulger (Nottawa, Canada);  Mahati Chintapalli (Mountain View, California);  Gabriel Iftime (Dublin, California);  Quentin Van Overmeere (Mountain View, California);  Jessica Louis Baker Rivest (Palo Alto, California);  Ravi Neelakantan (Redwood City, California);  Stephen Meckler (Redwood City, California)
ABSTRACT A method of producing a polymer aerogel includes dissolving precursors into a solvent, wherein the precursors include monomers, crosslinkers, a controlling agent and an initiator to form a precursor solution, wherein at least one of the monomers or at least one of the crosslinkers has a refractive index of 1.5 or lower, polymerizing the precursor solution to form a gel polymer, and removing the solvent from the gel polymer to produce the polymer aerogel. A method of producing a polymer aerogel include dissolving precursors into a solvent, wherein the precursors include monomers, crosslinkers, a controlling agent and an initiator to form a precursor solution, polymerizing the precursor solution to form a gel polymer, removing the solvent from the gel polymer to produce the polymer aerogel, and reducing a refractive index of one of either the gel polymer or the polymer aerogel.
FILED Friday, April 30, 2021
APPL NO 17/245418
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/242 (20130101)
C08J 9/0004 (20130101) Original (OR) Class
C08J 9/286 (20130101)
C08J 2205/026 (20130101)
C08J 2205/044 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/0025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851648 Kawaoka et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Centers of Excellence for Influenza Research and Surveillance (CEIRS)
APPLICANT(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin);  The University of Tokyo (Tokyo, Japan)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin);  The University of Tokyo (Tokyo, Japan)
INVENTOR(S) Yoshihiro Kawaoka (Middleton, Wisconsin);  Kosuke Takada (Tokyo, Japan);  Masaki Imai (Kawasaki, Japan)
ABSTRACT A mammalian or avian cell line that expresses high levels of human influenza virus receptors is provided. In one embodiment, the cell line supports human influenza virus, e.g., human A/H3 influenza virus, isolation and growth much more effectively than corresponding conventional (unmodified) cells or in corresponding human virus receptor-overexpressing cells, and the propagated viruses may maintain higher genetic stability than in the corresponding cells.
FILED Friday, February 07, 2020
APPL NO 16/785449
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0602 (20130101)
C12N 9/10 (20130101)
C12N 15/102 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/04 (20130101)

Enzymes
C12Y 204/99001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851652 Porteus et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR (Stanford, California);  UNIVERSITY and AGILENT TECHNOLOGIES, INC. (Santa Clara, California)
INVENTOR(S) Matthew H. Porteus (Stanford, California);  Ayal Hendel (Stanford, California);  Joe Clark (Stanford, California);  Rasmus O. Bak (Stanford, California);  Daniel E. Ryan (Santa Clara, California);  Douglas J. Dellinger (Santa Clara, California);  Robert Kaiser (Santa Clara, California);  Joel Myerson (Santa Clara, California)
ABSTRACT Provided herein are methods for inducing CRISPR/Cas-based gene regulation (e.g., genome editing or gene expression) of a target nucleic acid (e.g., target DNA or target RNA) in a cell. The methods include using modified single guide RNAs (sgRNAs) that enhance gene regulation of the target nucleic acid in a primary cell for use in ex vivo therapy or in a cell in a subject for use in in vivo therapy. Additionally, provided herein are methods for preventing or treating a genetic disease in a subject by administering a sufficient amount of a modified sgRNA to correct a mutation in a target gene associated with the genetic disease.
FILED Monday, March 14, 2022
APPL NO 17/694361
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/96 (20130101)
C12N 15/11 (20130101) Original (OR) Class
C12N 15/111 (20130101)
C12N 15/907 (20130101)
C12N 2310/10 (20130101)
C12N 2310/20 (20170501)
C12N 2310/315 (20130101)
C12N 2310/321 (20130101)
C12N 2310/346 (20130101)
C12N 2310/531 (20130101)
C12N 2320/51 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851657 Gao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Guangping Gao (Westborough, Massachusetts);  Yi Lu (Shanghai, China PRC);  Qiang Zheng (Chengdu, China PRC);  Xun Xu (Shanghai, China PRC);  Phillip D. Zamore (Northborough, Massachusetts);  Phillip Tai (Worcester, Massachusetts)
ABSTRACT The disclosure relates, in some aspects, to compositions and methods for treating corneal disease (e.g., corneal neovascularization. In some embodiments, the disclosure relates to rAAV-mediated delivery of an cornea-associated transgene to a subject. In some embodiments, the rAAV transduces the corneal tissue of a subject.
FILED Wednesday, June 09, 2021
APPL NO 17/342587
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0048 (20130101)
A61K 48/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/113 (20130101)
C12N 2310/141 (20130101)
C12N 2320/32 (20130101)
C12N 2330/51 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851665 Williams
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Aldevron, L.L.C. (South Fargo, North Dakota)
ASSIGNEE(S) ALDEVRON, L.L.C. (Fargo, North Dakota)
INVENTOR(S) James A. Williams (Lincoln, Nebraska)
ABSTRACT A eukaryotic replicative pUC-free minicircle expression vector is provided. The eukaryotic replicative pUC-free minicircle expression vector includes a pUC-free eukaryotic region sequence encoding a transgene of interest and comprising 5′ and 3′ ends and a ii) pUC-free spacer region of less than 500 basepairs in length linking the 5′ and 3′ ends of the eukaryotic region sequences and comprising a bacterial R6K replication origin having at least 95% sequence identity to SEQ ID NO: 11 and SEQ ID NO: 12 and a RNA selectable marker, the RNA selectable marker being an RNA-IN regulating RNA-OUT functional variant having at least 95% sequence identity to SEQ ID NO: 20 or SEQ ID NO: 22.
FILED Thursday, September 24, 2020
APPL NO 17/031791
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101)
C12N 15/64 (20130101)
C12N 15/67 (20130101)
C12N 15/79 (20130101) Original (OR) Class
C12N 15/85 (20130101)
C12N 2800/24 (20130101)
C12N 2800/107 (20130101)
C12N 2820/55 (20130101)
C12N 2830/42 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)
C12P 21/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851670 Jaenisch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) Rudolf Jaenisch (Brookline, Massachusetts);  Bryce Woodbury Carey (New York, New York);  Yaqub Hanna (Tel Aviv, Israel)
ABSTRACT The disclosure relates to a method of reprogramming one or more somatic cells, e.g., partially differentiated or fully/terminally differentiated somatic cells, to a less differentiated state, e.g., a pluripotent or multipotent state. In further embodiments the invention also relates to reprogrammed somatic cells produced by methods of the invention, to chimeric animals comprising reprogrammed somatic cells of the invention, to uses of said cells, and to methods for identifying agents useful for reprogramming somatic cells.
FILED Tuesday, June 11, 2019
APPL NO 16/438424
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0271 (20130101)

Peptides
C07K 14/4705 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0606 (20130101)
C12N 5/0696 (20130101)
C12N 15/79 (20130101)
C12N 15/85 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2501/60 (20130101)
C12N 2501/602 (20130101)
C12N 2501/603 (20130101)
C12N 2501/604 (20130101)
C12N 2501/605 (20130101)
C12N 2501/606 (20130101)
C12N 2501/608 (20130101)
C12N 2506/11 (20130101)
C12N 2506/115 (20130101)
C12N 2510/00 (20130101)
C12N 2740/15041 (20130101)
C12N 2740/15043 (20130101)
C12N 2740/16043 (20130101)
C12N 2799/027 (20130101)
C12N 2800/108 (20130101)
C12N 2840/203 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851699 Ellington et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Andrew Ellington (Austin, Texas);  Yu Sherry Jiang (Austin, Texas);  Sanchita Bhadra (Austin, Texas);  Bingling Li (Austin, Texas);  Randy Allen Hughes (Austin, Texas);  Yan Du (Austin, Texas);  Jimmy Gollihar (Hewitt, Texas)
ABSTRACT Disclosed are methods for isothermal nucleic acid amplification and detection.
FILED Friday, February 05, 2021
APPL NO 17/168940
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101) Original (OR) Class
C12Q 1/6844 (20130101)
C12Q 1/6844 (20130101)
C12Q 1/6897 (20130101)
C12Q 2525/301 (20130101)
C12Q 2527/101 (20130101)
C12Q 2531/119 (20130101)
C12Q 2565/107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851702 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Feng Zhang (Cambridge, Massachusetts);  Jonathan Gootenberg (Cambridge, Massachusetts);  Omar Abudayyeh (Cambridge, Massachusetts);  Julia Joung (Cambridge, Massachusetts);  Alim Ladha (Cambridge, Massachusetts);  Han Altae-Tran (Cambridge, Massachusetts);  Guilhem Faure (Cambridge, Massachusetts)
ABSTRACT Systems and methods for rapid diagnostics related to the use of isothermal amplification reagents for detection of microbial species, including coronavirus, and methods of use, are provided.
FILED Friday, June 05, 2020
APPL NO 16/894664
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502 (20130101)
B01L 3/502715 (20130101)
B01L 7/52 (20130101)
B01L 2300/0816 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/78 (20130101)
C12N 9/1276 (20130101)
C12N 2310/20 (20170501)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/701 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6844 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)
C12Q 2600/156 (20130101)

Enzymes
C12Y 207/07049 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2333/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851711 Vrba et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Lukas Vrba (Tucson, Arizona);  Bernard W. Futscher (Tucson, Arizona)
ABSTRACT Cancer specific DNA methylation regions have been studied to find cancer specific DNA methylation markers for most common cancers. Differentially methylated regions for individual cancer types were identified and those were further filtered against data from normal tissues to obtain marker regions with cancer specific methylation, resulting in total of 1,250 hypermethylated and 584 hypomethylated marker CpGs. Optimal sets of six markers for each TCGA cancer type that could identify most tumors with high specificity and sensitivity (AUC 0.969-1.00) were chosen from hypermethylated markers and a universal 12 marker set that can detect tumors of all 33 TCGA cancer types (AUC>0.84) was also chosen from hypermethylated markers.
FILED Monday, October 01, 2018
APPL NO 16/651871
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/154 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851716 Kurtz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) David M. Kurtz (San Carlos, California);  Maximilian Diehn (San Carlos, California);  Arash Ash Alizadeh (San Mateo, California)
ABSTRACT Processes and materials to detect cancer from a biopsy are described. In some cases, cell-free nucleic acids can be sequenced, and the sequencing result can be utilized to detect sequences derived from a neoplasm. Detection of somatic variants occurring in phase can indicate the presence of cancer in a diagnostic scan and a clinical intervention can be performed.
FILED Thursday, November 17, 2022
APPL NO 18/056652
ART UNIT 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1089 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/112 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2800/7028 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
G16B 20/10 (20190201)
G16B 20/20 (20190201)
G16B 30/00 (20190201)
G16B 30/10 (20190201)
G16B 35/20 (20190201)
G16B 40/00 (20190201)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/40 (20180101)
G16H 10/60 (20180101)
G16H 20/10 (20180101)
G16H 50/20 (20180101)
G16H 50/30 (20180101)
G16H 50/70 (20180101)
G16H 70/60 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852474 Vakoc et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Benjamin J. Vakoc (Arlington, Massachusetts);  Norman Lippok (Quincy, Massachusetts)
ABSTRACT A method including: scanning a sample over a period of time using an electro-magnetic radiation source, the period of time including a first time period and a second time period, a sample portion of the electro-magnetic radiation source being directed to the sample in a sample arm of an optical interferometric system, and a reference portion of the electro-magnetic radiation source being directed to a reference arm of the optical interferometric system; applying, using a phase modulator, a phase shift comprising a first phase shift and a second phase shift to at least one of the reference portion or the sample portion of the electro-magnetic radiation source, the first phase shift being applied during the first time period and the second phase shift being applied during the second time period, the second phase shift having a difference of 90 degrees from the first phase shift; acquiring in-phase data based on a first interference between first backscattered electro-magnetic radiation during the first time period and the at least one of the reference portion or the sample portion subjected to the first phase shift; acquiring quadrature data based on a second interference between second backscattered electro-magnetic radiation during the second time period and the at least one of the reference portion or the sample portion subjected to the second phase shift; and determining a complex interference signal based on the in-phase data and the quadrature data.
FILED Tuesday, July 30, 2019
APPL NO 17/264165
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/0201 (20130101) Original (OR) Class
G01B 9/02008 (20130101)
G01B 9/02091 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/10101 (20130101)
G06T 2207/30004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852493 Schaefer
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Philip Raymond Schaefer (Weaverville, North Carolina)
ASSIGNEE(S) Vortant Technologies, LLC (Weaverville, North Carolina)
INVENTOR(S) Philip Raymond Schaefer (Weaverville, North Carolina)
ABSTRACT A system provides feedback to a user to guide the user to point a part of the body at a target of interest. An angle sensor senses the angle in which the part of the user's body is pointing, such as the head or the hand. The system computes the angle to a target and compares to the angle in which the part of the user's body is pointing and the feedback indicates to the user how to point more closely to the direction of the target. Additional sensors allow the system to update the angle to the target as the position of the user changes. A walking sensor is disclosed to accurately measure the position of the user.
FILED Tuesday, June 15, 2021
APPL NO 17/348256
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3415 (20130101) Original (OR) Class
G01C 21/3476 (20130101)
G01C 21/3629 (20130101)

Electric Digital Data Processing
G06F 3/011 (20130101)
G06F 3/012 (20130101)
G06F 3/013 (20130101)
G06F 3/016 (20130101)
G06F 3/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852631 Haq et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Rizwan Haq (Boston, Massachusetts);  Cecile Marie Gstalder (Boston, Massachusetts)
ABSTRACT The present invention is based in part on the identification of Fbxw7 as a biomarker predictive of responsiveness to anti-immune checkpoint therapies.
FILED Friday, January 18, 2019
APPL NO 16/771802
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)
A61K 2039/507 (20130101)
A61K 2039/545 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

Peptides
C07K 16/2818 (20130101)
C07K 2317/24 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/113 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5017 (20130101)
G01N 33/57492 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852704 Annio et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Siemens Healthcare GmbH (Erlangen, Germany);  Centre National de la Recherche Scientifique (CNRS) (Paris, France);  Institut National de La Sante et de la Recherche Medicale (INSERM) (Paris, France);  King's College London (London, United Kingdom);  Department of Health and Human Services (Bethesda, Maryland);  UNIV PARIS XIII PARIS-NORD VILLETANEUSE (Villetaneuse, France);  Universite de Paris (Paris, France)
ASSIGNEE(S) Siemens Healthcare GmbH (Erlangen, Germany);  Centre National de la Recherche Scientifique (CNRS) (Paris, France);  Institut National de La Sante et de la Recherche Medicale (INSERM) (Paris, France);  King's College London (London, United Kingdom);  Department of Health and Human Services (Bethesda, Maryland);  UNIV PARIS XIII PARIS-NORD VILLETANEUSE (Villetaneuse, France);  Universite de Paris (Paris, France)
INVENTOR(S) Giacomo Annio (Mola di Bari Ba, Italy);  Verena Muller-Reinwald (Bayern, Germany);  Ralph Sinkus (Parmain, France);  Omar Darwish (London, United Kingdom);  Wilfried Schnell (Forchheim, Germany);  Tamara Elisabeth Falkner (Schwabach, Germany);  Ahmed M. Gharib (Bethesda, Maryland)
ABSTRACT The present disclosure is directed to a motor for a magnetic resonance (MR) tomography room, to a patient table for the MR room, to a MR elastography device, and to a MR tomography device. A MR tomography device for a MR elastography imaging protocol is arranged within the MR tomography room, and includes a rotational drive for supplying rotational energy to power a MR elastography transducer usable during the MR elastography imaging protocol, and a support structure. The rotational drive comprises a terminal for connecting the MR elastography transducer to the rotational drive, and a bearing means configured such that the position of the terminal relative to the support structure is adaptable along a trajectory predetermined by the bearing means. The rotational drive is mounted to the support structure via the bearing means.
FILED Thursday, March 17, 2022
APPL NO 17/697492
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/704 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/48 (20130101) Original (OR) Class
G01R 33/56358 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852706 Madhuranthakam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Ananth J. Madhuranthakam (Coppell, Texas);  Robert E. Lenkinski (Dallas, Texas);  Xinzeng Wang (Dallas, Texas);  Ivan Pedrosa (Dallas, Texas)
ABSTRACT The present invention includes a method and apparatus for improved magnetic resonance imaging with simultaneous fat and fluid suppression of a subject comprising: acquiring four images, in-phase (IP) and out-of-phase (OP) at a short and a long echo time (TE) using a single-shot turbo spin echo from one or more magnetic resonance imager excitations: processing at least a pair of IP and OP images at a short and a long TE using single-shot turbo spin echo using a Dixon reconstruction; processing the pair of IP and OP images; subtracting the long TE water-only image from the shared-field-map Dixon reconstruction from the short TE water-only image to provide a fluid attenuation; processing water-only and fat-only images at the short and long TE to generate quantitative fat-fraction map; and reconstructing one or more 3D magnetic resonance images.
FILED Friday, February 08, 2019
APPL NO 16/967894
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0036 (20180801)
A61B 5/055 (20130101)
A61B 18/02 (20130101)
A61B 2017/320069 (20170801)
A61B 2018/00577 (20130101)
A61B 2018/00791 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4828 (20130101) Original (OR) Class
G01R 33/5602 (20130101)
G01R 33/5607 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11853087 Ismagilov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Rustem F. Ismagilov (Chicago, Illinois);  Bo Zheng (Chicago, Illinois);  Cory John Gerdts (Chicago, Illinois)
ABSTRACT The present invention provides microfluidic technology enabling rapid and economical manipulation of reactions on the femtoliter to microliter scale.
FILED Monday, August 03, 2020
APPL NO 16/983270
ART UNIT 1796 — Optics
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 25/314 (20220101)
B01F 33/3021 (20220101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101)
B01J 2219/0059 (20130101)
B01J 2219/00522 (20130101)
B01J 2219/00585 (20130101)
B01J 2219/00599 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0293 (20130101)
B01L 3/502746 (20130101)
B01L 3/502784 (20130101)
B01L 2200/0673 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0838 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/0487 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/38 (20130101)
G01N 35/08 (20130101)
G01N 2035/1034 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 7/0694 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 137/0318 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11853244 Sankaralingam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Karthikeyan Sankaralingam (Madison, Wisconsin);  Anthony Nowatzki (Madison, Wisconsin);  Vinay Gangadhar (Madison, Wisconsin)
ABSTRACT A reconfigurable hardware accelerator for computers combines a high-speed dataflow processor, having programmable functional units rapidly reconfigured in a network of programmable switches, with a stream processor that may autonomously access memory in predefined access patterns after receiving simple stream instructions. The result is a compact, high-speed processor that may exploit parallelism associated with many application-specific programs susceptible to acceleration.
FILED Thursday, January 26, 2017
APPL NO 15/416670
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3455 (20130101)
G06F 9/3834 (20130101)
G06F 9/3877 (20130101)
G06F 9/4494 (20180201)
G06F 9/30087 (20130101)
G06F 13/1689 (20130101)
G06F 13/4022 (20130101) Original (OR) Class
G06F 15/76 (20130101)
G06F 15/825 (20130101)
G06F 15/7889 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11854202 Fan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Yong Fan (Bala Cynwyd, Pennsylvania);  Hongming Li (Philadelphia, Pennsylvania)
ABSTRACT Methods and systems for analyzing images are disclosed. An example method may comprise inputting one or more of a first image or a second image into a fully convolutional network, and determining an updated fully convolutional network by optimizing a similarity metric associated with spatially transforming the first image to match the second image. The one or more values of the fully convolutional network may be adjusted to optimize the similarity metric. The method may comprise registering one or more of the first image or the second image based on the updated fully convolutional network.
FILED Friday, May 27, 2022
APPL NO 17/826567
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 18/22 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/0014 (20130101) Original (OR) Class
G06T 7/33 (20170101)
G06T 2207/10081 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/20081 (20130101)

Image or Video Recognition or Understanding
G06V 10/25 (20220101)
G06V 10/82 (20220101)
G06V 10/7515 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11854281 Kaufman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S) Arie Kaufman (Plainview, New York);  Saeed Boorboor (Lake Grove, New York)
ABSTRACT An exemplary system, method, and computer-accessible medium for generating an image(s) of an anatomical structure(s) in a biological sample(s) can include receiving first wide field microscopy imaging information for the biological sample, generating second imaging information by applying a gradient-based distance transform to the first imaging information, and generating the image(s) based on the second imaging information. The second imaging information can be generated by applying an anisotropic diffusion procedure to the first imaging information. The second imaging information can be generated by applying a curvilinear filter and a Hessian-based enhancement filter after the application of the gradient-based distance transform. The second information can be generated by applying (i) a tube enhancement procedure or (ii) a plate enhancement procedure after the application of the gradient-based distance transform.
FILED Monday, August 17, 2020
APPL NO 16/994885
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/20021 (20130101)
G06T 2207/30016 (20130101)
G06T 2207/30024 (20130101)

Image or Video Recognition or Understanding
G06V 20/695 (20220101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11854701 Constantine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Gregory M. Constantine (Baden, Pennsylvania);  Timothy Billiar (Presto, Pennsylvania);  Qi Mi (Pittsburgh, Pennsylvania);  Rami Namas (Bethel Park, Pennsylvania);  Lukas Schimunek (Rimbach, Germany);  Yoram Vodovotz (Sewickley, Pennsylvania)
ABSTRACT Provided herein are methods for segregating trauma, e.g., blunt trauma, patients into different cohorts based on risk of multiple organ dysfunction syndrome using patient data obtained within a short time window following injury. The methods are useful in providing treatment to trauma patients, and for separating trauma patients into cohorts.
FILED Monday, September 13, 2021
APPL NO 17/473726
ART UNIT 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/20 (20190201)
G16B 40/00 (20190201)
G16B 40/30 (20190201)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/10 (20180101)
G16H 50/20 (20180101)
G16H 50/30 (20180101) Original (OR) Class
G16H 50/70 (20180101)
G16H 70/40 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11849781 Merrill
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts)
ASSIGNEE(S) Government of the United States as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Haile A. Merrill (Natick, Massachusetts)
ABSTRACT Apparel that is adjustable. For example, in one embodiment, the apparel is provided that includes a torso. The torso includes a front, a back, a first side connecting the front to the back, a second side connecting the front to the back, a bottom, and a top. A plurality of shell fabric portions is on the torso. Each portion in the plurality of portions of shell fabric is adapted to receive an elastomeric member. Bunched fabric is on the first side and second side of the torso. Pleats are on the front of the torso. A centrally located flap is on the torso and has a longitudinal axis that is substantially vertical. Sleeves are connected to the torso. A first zipper track is located on the bottom of the torso. Pants may include a second zipper track adapted to mate with the first zipper track and secure the pants to the torso.
FILED Monday, April 25, 2022
APPL NO 17/727882
ART UNIT 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 1/06 (20130101)
A41D 3/00 (20130101)
A41D 13/02 (20130101) Original (OR) Class
A41D 2300/22 (20130101)
A41D 2300/32 (20130101)
A41D 2300/322 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850001 Hu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Juejun Hu (Newton, Massachusetts);  Tian Gu (Fairfax, Virginia);  Mikhail Shalaginov (Somerville, Massachusetts);  Fan Yang (Cambridge, Massachusetts)
ABSTRACT Meta-lens based ocular imaging, near-eye display, and eye-tracking systems are described. The systems can include a single focusing optic and an integrated circuit that provides illumination light and includes an imaging array. The focusing optic includes meta-atoms formed on a substrate. The systems may have no moving parts and achieve imaging or image-projection fields-of-view approaching or exceeding 180 degrees. Because of their low part count, the systems can be robust and have a very small form factor.
FILED Monday, December 20, 2021
APPL NO 17/556884
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/12 (20130101)
A61B 3/14 (20130101) Original (OR) Class
A61B 3/113 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 27/0093 (20130101)
G02B 27/0172 (20130101)
G02B 2027/0123 (20130101)
G02B 2027/0147 (20130101)

Electric Digital Data Processing
G06F 3/013 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850290 Lu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy Kuan-Ta Lu (Cambridge, Massachusetts);  Xinyue Liu (Cambridge, Massachusetts);  Tzu-Chieh Tang (Boston, Massachusetts);  Eléonore Claire Tham (Cambridge, Massachusetts);  Xuanhe Zhao (Allston, Massachusetts)
ABSTRACT Provided herein, in some embodiments, are hydrogel-elastomer and hydrogel-alginate devices, compositions and associated methods to encapsulate living cells.
FILED Thursday, July 20, 2017
APPL NO 16/318958
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/6806 (20130101)
A61B 5/6833 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0073 (20130101)
A61K 49/0097 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 11/04 (20130101)
C12N 11/10 (20130101)
C12N 15/63 (20130101)
C12N 15/70 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6897 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850341 Burbank et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) NxStage Medical, Inc. (Lawrence, Massachusetts)
ASSIGNEE(S) NxStage Medical, Inc. (Lawrence, Massachusetts)
INVENTOR(S) Jeffrey H. Burbank (Manchester, Massachusetts);  Dennis M. Treu (Castle Rock, Colorado);  Daniel Joseph Rubery, Jr. (Nashua, New Hampshire);  Scott W. Newell (Ipswich, Massachusetts);  James M. Brugger (Newburyport, Massachusetts);  William J. Schnell (Libertyville, Illinois);  William K. Weigel (Portland, Maine);  Steven A. White (Hudson, Massachusetts);  Mark T. Wyeth (Andover, Massachusetts);  Jerome James (Vestavia, Alabama);  David Desouza (Essex, Massachusetts);  Joseph E. Turk, Jr. (North Andover, Massachusetts);  Garrett Casey (Methuen, Massachusetts)
ABSTRACT The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.
FILED Tuesday, August 02, 2022
APPL NO 17/879455
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/14 (20130101)
A61M 1/34 (20130101)
A61M 1/165 (20140204)
A61M 1/341 (20140204)
A61M 1/1605 (20140204) Original (OR) Class
A61M 1/1613 (20140204)
A61M 1/1615 (20140204)
A61M 1/1647 (20140204)
A61M 1/3403 (20140204)
A61M 1/3434 (20140204)
A61M 1/3437 (20140204)
A61M 1/3441 (20130101)
A61M 1/3444 (20140204)
A61M 1/3448 (20140204)
A61M 1/3607 (20140204)
A61M 1/3609 (20140204)
A61M 1/3635 (20140204)
A61M 2205/05 (20130101)
A61M 2205/058 (20130101)
A61M 2205/502 (20130101)
A61M 2205/702 (20130101)
A61M 2205/3331 (20130101)
A61M 2205/3334 (20130101)
A61M 2205/3341 (20130101)
A61M 2205/3351 (20130101)
A61M 2205/3355 (20130101)
A61M 2205/3365 (20130101)
A61M 2205/3368 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850469 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Michael Anderson (Colorado Springs, Colorado);  Christopher Klinke (Lafayette, Colorado)
ABSTRACT A finger strengthening device (FSD) includes a plurality of finger strengthening elements formed therewith. The FSD is attachable to a structure in a plurality of different orientations to permit a variation in finger exercise techniques.
FILED Wednesday, September 08, 2021
APPL NO 17/468737
ART UNIT 3784 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 21/4035 (20151001)
A63B 21/4045 (20151001)
A63B 23/16 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850619 Pringle, IV et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) THE BOEING COMPANY (Chicago, Illinois)
INVENTOR(S) John Walter Pringle, IV (Torrance, California);  Angelica Davancens (Reseda, California);  Ryan Vutha Touch (Irvine, California)
ABSTRACT A robot end effector (100) for dispensing an extrudable substance (102) comprises a chassis (110), a static mixer (101), and cartridge bays (122), extending from the chassis (110). Each of the cartridge bays (122) is shaped to receive a corresponding one of the two-part cartridges (104). Fluidic communication between the selected one of the two-part cartridges (104) and the static mixer (101) is established when the cartridge bays (122) are moved to a predetermined position with respect to the chassis (110). The robot end effector (100) comprises a dispensing valve (130), attached to the chassis (110), and a head assembly (150), comprising pairs of fittings (152). Each of the pairs of fittings (152) is configured to selectively supply compressed air from a pressure source (199) to contents of a corresponding one of the two-part cartridges (104).
FILED Thursday, September 09, 2021
APPL NO 17/470555
ART UNIT 3754 — Fluid Handling and Dispensing
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 25/42 (20220101)
B01F 2101/2305 (20220101)

Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 7/12 (20130101)
B05B 7/26 (20130101)
B05B 7/0408 (20130101) Original (OR) Class

Manipulators; Chambers Provided With Manipulation Devices
B25J 15/0019 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850816 Bro et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Tewksbury, Massachusetts)
INVENTOR(S) Mitchell Bro (Tucson, Arizona);  John Tristan Elmer (Tucson, Arizona);  Jarrod Salmon (Tucson, Arizona);  William Straus (Tucson, Arizona)
ABSTRACT An arbor press includes a limiter for limiting load and/or travel of a ram used to press on an object. The ram includes a pair of pieces, a shaft and a sleeve, which are capable of relative translation, modulated by the spring. The spring may be preloaded, and configured to prevent overloading of the object, by limiting the transmission of force through the ram. The ram may also be configured to limit travel of the ram. The arbor press may include gearing to translate rotational movement of a handle to translational movement of the ram. The gearing may include a rack that is part of or is coupled to the shaft, and a pinion that is connected to the handle. Parts of the arbor press may be enclosed in a housing, to contain debris from metal-to-metal sliding in the arbor press, facilitating use in clean rooms.
FILED Thursday, September 02, 2021
APPL NO 17/464818
ART UNIT 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Presses in General
B30B 1/04 (20130101) Original (OR) Class
B30B 15/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851178 Beck et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Steven Beck (Palos Verdes Estates, California);  David Caldwell (Carlsbad, California);  Christopher Hartney (Gardena, California);  Bernard Harris Jefferson, Jr. (Westminster, California);  Jeffrey Lang (Torrance, California);  John Morales (Victorville, California);  Martin Panevsky (San Pedro, California);  Kasemsan Siri (Torrance, California);  Evan Ulrich (Hermosa Beach, California);  Richard Welle (Huntington Beach, California);  Allyson Yarbrough (Rancho Palos Verdes, California)
ABSTRACT An unmanned aerial vehicle (UAV) that provides increased operational flight endurance and efficiency. The UAV includes a power generation system, which includes an internal combustion engine and one or more batteries (batteries). The power generation system is configured to generate power for propulsion of the UAV. The internal combustion engine is configured to power a lift propeller, generating vertical lift of the UAV, and the batteries are configured to power a micro-propeller assembly, propelling the UAV in a forward direction or multiple additional directions.
FILED Friday, February 14, 2020
APPL NO 16/791605
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101) Original (OR) Class

Unmanned aerial vehicles [UAV]; equipment therefor
B64U 10/13 (20230101)
B64U 30/20 (20230101)
B64U 50/11 (20230101)
B64U 50/13 (20230101)
B64U 50/14 (20230101)
B64U 50/19 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851382 Basom et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Kenneth B. Basom (Waldorf, Maryland);  Bryan Milani (Port Tobacco, Maryland)
ABSTRACT The conformable pyrolant includes a fluorocarbon liquid, a fluorocarbon powder, and a micron size powdered aluminum bound together with a binder system that includes polyisobutylene and colloidal silicon dioxide. The conformable pyrolant is capable of achieving temperatures on the order 10,000° F., which will breach an ordnance item and thermally decompose an insensitive explosive fill. The conformable pyrolant also includes tungsten, wherein tungsten and silicon dioxide oxidize into fluorinated compounds, therein extending the burn and gasifying, therein enhancing ebullition and volume in general. The versatile conformable format is capable of being shaped into geometries for inclusion in ordnance items or molded into configurations for disposal of insensitive munitions.
FILED Thursday, August 29, 2019
APPL NO 16/602212
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 21/0033 (20130101)
C06B 27/00 (20130101) Original (OR) Class
C06B 47/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851391 Garneau-Tsodikova et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Prostate Cancer Research Program (USAMRMCPCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Sylvie Garneau-Tsodikova (Lexington, Kentucky);  David S. Watt (Lexington, Kentucky);  Nishad Thamban Chandrika (Lexington, Kentucky)
ABSTRACT An antifungal composition and a method of treating a systemic fungal infection are provided herein. The antifungal composition includes a diaryl bishydrazone. The method includes administering a therapeutically effective amount of the diaryl bishydrazone to a subject in need thereof.
FILED Wednesday, July 17, 2019
APPL NO 16/514276
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/10 (20180101)

Acyclic or Carbocyclic Compounds
C07C 243/10 (20130101) Original (OR) Class
C07C 277/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851478 Crowe, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) James E Crowe, Jr. (Nashville, Tennessee)
ABSTRACT The present disclosure is directed to antibodies binding to and neutralizing Chikungunya virus (CHIKV) and methods for use thereof.
FILED Friday, January 04, 2019
APPL NO 16/959760
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/1081 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/56 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851647 Santiago et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Juan G Santiago (Stanford, California);  Lewis A. Marshall (Pleasanton, California);  Anita Rogacs (Los Altos, California)
ABSTRACT Various aspects of the present disclosure are directed toward methods and apparatuses for interacting a first liquid and a second liquid in one or more fluidic channels of a capillary structure. The methods and apparatuses can include providing at least one capillary barrier that positions a meniscus of the first liquid at a fluid-interface region using capillary forces within the capillary structure. Additionally, a path is provided along one of the channels for the second liquid to flow toward the fluid-interface region. Additionally, gas pressure is released, via a gas-outflow port, from the fluid-interface region while flow of the first liquid is arrested. Further, the first liquid and the second liquid contact in the fluid-interface region with the capillary barrier holding the first liquid at the fluid-interface region.
FILED Thursday, August 20, 2020
APPL NO 16/998839
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Separation
B01D 57/02 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 3/502723 (20130101)
B01L 3/502738 (20130101)
B01L 2200/10 (20130101)
B01L 2200/027 (20130101)
B01L 2200/0621 (20130101)
B01L 2200/0631 (20130101)
B01L 2200/0684 (20130101)
B01L 2300/12 (20130101)
B01L 2300/165 (20130101)
B01L 2300/0838 (20130101)
B01L 2300/0858 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/086 (20130101)
B01L 2400/088 (20130101)
B01L 2400/0406 (20130101)
B01L 2400/0421 (20130101)
B01L 2400/0688 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/101 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44791 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851651 Banal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) James Banal (Cambridge, Massachusetts);  Joseph Don Berleant (Cambridge, Massachusetts);  Tyson Shepherd (Arlington, Massachusetts);  Mark Bathe (Cambridge, Massachusetts)
ABSTRACT Methods for the automated template-free synthesis of user-defined sequence controlled biopolymers using microfluidic devices are described. The methods facilitate simultaneous synthesis of up to thousands of uniquely addressed biopolymers from the controlled movement and combination of regents as fluid droplets using microfluidic and EWOD-based systems. In some forms, biopolymers including nucleic acids, peptides, carbohydrates, and lipids are synthesized from step-wise assembly of building blocks based on a user-defined sequence of droplet movements. In some forms, the methods synthesize uniquely addressed nucleic acids of up to 1,000 nucleotides in length. Methods for adding, removing and changing barcodes on biopolymers are also provided. Biopolymers synthesized according to the methods, and libraries and databases thereof are also described. Modified biopolymers, including chemically modified nucleotides and biopolymers conjugated to other molecules are described.
FILED Tuesday, June 19, 2018
APPL NO 16/012583
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101)
B01J 2219/0065 (20130101)
B01J 2219/00675 (20130101)
B01J 2219/00722 (20130101)
B01J 2219/00725 (20130101)
B01J 2219/00729 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502784 (20130101)
B01L 3/502792 (20130101)
B01L 2400/0427 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1068 (20130101) Original (OR) Class
C12N 15/1093 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6811 (20130101)
C12Q 2565/629 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 35/00 (20190201)
G16B 40/00 (20190201)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/60 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851698 Rininsland et al.
FUNDED BY
Department of Defense (DOD)
Defense Logistics Agency (DLA)
APPLICANT(S) Mesa Photonics, LLC (Santa Fe, New Mexico)
ASSIGNEE(S) MESA PHOTONICS, LLC (Santa Fe, New Mexico)
INVENTOR(S) Frauke Henrike Rininsland (Santa Fe, New Mexico);  Daniel James Kane (Santa Fe, New Mexico)
ABSTRACT The present invention relates to a method for detecting a pathogen in cellular lysate by measuring pathogen-specific enzyme activity. The method comprises contacting the cellular lysate with a substrate the pathogen of interest recognizes and modifies, and obtaining a measurable, recordable, signal. The method may comprise detection of SARS-CoV viruses using the activity of SARS PLpro enzyme in tongue scrape lysate as a readout.
FILED Sunday, February 05, 2023
APPL NO 18/105864
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/37 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101)
G01N 2333/165 (20130101)
G01N 2333/9513 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851699 Ellington et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Andrew Ellington (Austin, Texas);  Yu Sherry Jiang (Austin, Texas);  Sanchita Bhadra (Austin, Texas);  Bingling Li (Austin, Texas);  Randy Allen Hughes (Austin, Texas);  Yan Du (Austin, Texas);  Jimmy Gollihar (Hewitt, Texas)
ABSTRACT Disclosed are methods for isothermal nucleic acid amplification and detection.
FILED Friday, February 05, 2021
APPL NO 17/168940
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101) Original (OR) Class
C12Q 1/6844 (20130101)
C12Q 1/6844 (20130101)
C12Q 1/6897 (20130101)
C12Q 2525/301 (20130101)
C12Q 2527/101 (20130101)
C12Q 2531/119 (20130101)
C12Q 2565/107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851712 McGrail et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Daniel McGrail (Houston, Texas);  Shiaw-Yih Lin (Houston, Texas);  Patrick Pilie (Houston, Texas);  Eric Jonasch (Houston, Texas);  Curtis Chun-Jen Lin (Houston, Texas)
ABSTRACT Methods for increasing immune therapy response and predicting likelihood of cancer metastasis by analyzing the expression of genes associated with replication stress response. In some aspects, cancers are treated with immune checkpoint inhibitors and/or MEK inhibitors. Methods for selecting patients by analyzing the expression of genes associated with a defect in replication stress response are also provided.
FILED Wednesday, March 06, 2019
APPL NO 16/978758
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6813 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852026 Nicholson
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Brian Nicholson (Dayton, Ohio)
ABSTRACT An exo-bearing system for a turbomachine is operable to improve aerodynamic efficiency and mechanical limits of rotor blades for fans, compressors, turbines, pumps and the like. The exo-bearing system is positioned between the tips of the blades and a surrounding structural housing. The exo-bearing system eliminates the air gap that is formed in prior art turbomachines and causes the blades to load in compression during operation which increases mechanical operability of the blades.
FILED Wednesday, January 11, 2023
APPL NO 18/095559
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 11/08 (20130101)
F01D 25/16 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/50 (20130101)
F05D 2240/307 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852077 Greene et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Raytheon Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RTX Corporation (Farmington, Connecticut)
INVENTOR(S) Christopher Britton Greene (Hebron, Connecticut);  James M. Donohue (Glastonbury, Connecticut);  Peter AT Cocks (South Glastonbury, Connecticut)
ABSTRACT A method for operating a rotating detonation engine, having a radially outer wall extending along an axis; a radially inner wall extending along the axis, wherein the radially inner wall is positioned within the radially outer wall to define an annular detonation chamber having an inlet and an outlet, wherein the method includes flowing liquid phase fuel along at least one wall of the radially inner wall and the radially outer wall in a direction from the outlet toward the inlet to cool the at least one wall and heat the liquid fuel to provide a heated liquid fuel; flowing the heated liquid fuel to a mixer at the inlet to reduce pressure of the heated liquid fuel, flash vaporize the heated liquid fuel and mix flash vaporized fuel with oxidant to produce a vaporized fuel-oxidant mixture; and detonating the mixture in the annular detonation chamber.
FILED Thursday, April 15, 2021
APPL NO 17/231487
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/24 (20130101)
F02C 5/00 (20130101)
F02C 7/224 (20130101) Original (OR) Class
F02C 7/264 (20130101)

Jet-propulsion Plants
F02K 7/02 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/36 (20130101)
F05D 2250/141 (20130101)
F05D 2260/99 (20130101)
F05D 2260/232 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/32 (20130101)
F23R 3/44 (20130101)
F23R 3/56 (20130101)
F23R 7/00 (20130101)
F23R 2900/03043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852101 Hundley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Aberdeen Proving Ground (APG)
APPLICANT(S) X-Bow Launch Systems Inc. (Albuquerque, New Mexico)
ASSIGNEE(S) X-Bow Launch Systems Inc. (Albuquerque, New Mexico)
INVENTOR(S) Jason Hundley (Albuquerque, New Mexico);  Mark Kaufman (Auburn, California);  Michael McPherson (Socorro, New Mexico)
ABSTRACT A method of making a multi-grained fuel grain for a rocket is disclosed, the method comprising the steps of using at least one nozzle to extrude a first propellant in an additive manufacturing process, the first propellant comprising a multi-grained fuel grain, the multi-grained fuel grain forming the at least one void, the at least one void facilitating variation in internal ballistics, forming sensors, said sensors permitting continuous monitoring and continuous modification such that a user controls the ballistics profile of a rocket motor, forming an electrically-controlled second propellant in contact with and operatively coupled to the sensors; and wherein the additive manufacturing process uses at least at least one nozzle to extrude raw materials.
FILED Thursday, May 20, 2021
APPL NO 17/325524
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 80/00 (20141201)

Jet-propulsion Plants
F02K 9/10 (20130101)
F02K 9/24 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/80 (20130101)
F05D 2230/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852104 Pinello-Benavides et al.
FUNDED BY
Department of Defense (DOD)
Defense MicroElectronics Activity (DMEA)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Jacob Pinello-Benavides (Tuscon, Arizona);  John Meschberger (Tucson, Arizona);  Stephen Moore (El Dorado Hills, California);  Edward Little, III (El Dorado Hills, California)
ABSTRACT A propulsion system includes multiple solid rocket motors that are activated by a single initiator. The rocket motors act in parallel, providing thrust in a single direction. The initiator activates an ignition charge that is in or operatively coupled to a plenum that transports hot gasses from the ignition charge to the rockets to be ignited. The plenum may be an annular plenum, which may be located in an annular manifold. The plenum may be an unchoked plenum, allowing flow of hot gasses without choking. The plenum may be lined with an insulator material. A cover may be used to cover the plenum, and also to receive the rocket motors. The rocket motors may be solid-fuel rocket motors. The individual rocket motors may have separate ignition booster charges coupled to the plenum, which are ignited by the ignition charge and which in turn ignite the propellant grains.
FILED Friday, September 03, 2021
APPL NO 17/466245
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Jet-propulsion Plants
F02K 9/32 (20130101)
F02K 9/95 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852181 Thomasson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Timothy James Thomasson (Woodford, Virginia);  Michael James Parsons (King George, Virginia)
ASSIGNEE(S) United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Timothy James Thomasson (Woodford, Virginia);  Michael James Parsons (King George, Virginia)
ABSTRACT An axially separable fastener for securing a structure is provided to detach upon command of an electric signal. The fastener includes a metal bolt, an external nut, a frangible ampoule containing a liquid metal eutectic and an internal plug. The bolt has a metal shank with proximal and distal ends. The shank includes a first head at the proximal end, and a first helical external thread and an axial bore with a first helical internal thread at the distal end. The fastener secures a structure in compression between the first head and the external nut. The external nut screws onto the first external thread. The ampoule contains a liquid metal eutectic. The ampoule is insertable into the bore. The internal plug includes a second head, an actuator mechanism, and an auger opposite thereto. The internal plug has a second helical external thread between the second head and the auger for screwing into the bore along the first internal thread. Upon receipt of the signal, the internal plug axially drives the auger towards the proximal end into the ampoule to release the eutectic, thereby fracturing the bolt.
FILED Monday, August 30, 2021
APPL NO 17/460781
ART UNIT 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing
F16B 31/005 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852232 Speller et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) Textron Innovations Inc. (Providence, Rhode Island)
ASSIGNEE(S) Textron Innovations Inc. (Providence, Rhode Island)
INVENTOR(S) Charles Hubert Speller (Flower Mound, Texas);  Ezra Mike Tiprigan (North Richland Hills, Texas)
ABSTRACT A drive system for an aircraft such as a tiltrotor aircraft. The drive system includes first and second gearbox assemblies in mechanical communication with each other. A first lubrication system is associated with the first gearbox assembly and includes a bifurcated tank configured to contain a lubricant in an operating chamber including a lower sump and in an emergency chamber including an upper sump. A second lubrication system is associated with the second gearbox assembly. An emergency pump is in fluid communication with the emergency chamber. The emergency pump is configured to supply the lubricant to the first gearbox assembly from the emergency chamber responsive to a failure in the first lubrication system. In addition, the emergency pump is configured to supply the lubricant to the second gearbox assembly and to the operating chamber from the emergency chamber responsive to a failure in the second lubrication system.
FILED Tuesday, November 01, 2022
APPL NO 17/978919
ART UNIT 3654 — Material and Article Handling
CURRENT CPC
Aeroplanes; Helicopters
B64C 29/0033 (20130101)

Gearing
F16H 57/0404 (20130101)
F16H 57/0417 (20130101)
F16H 57/0436 (20130101)
F16H 57/0442 (20130101) Original (OR) Class
F16H 57/0445 (20130101)
F16H 57/0453 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852444 Pinsky et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James Gregory Pinsky (Remington, Virginia);  Philip J. Dudt (North Bethesda, Maryland);  Devin P. Murphy (Sterling, Virginia)
ABSTRACT According to exemplary inventive practice, a personal armor system includes a textile-based layer not exceeding ½-half-inch thickness, and an elastomeric coating not exceeding ⅛-inch thickness. The textile-based layer includes a fiber reinforcement and a resin binder. The combined areal density of the textile-based layer and the elastomeric coating does not exceed 2.5 psf. According to a first mode of inventive practice, the elastomeric coating is essentially a strain-rate-sensitivity-hardening elastomer, and the areal density of the textile-based layer does not exceed 2.3 psf. According to a second mode of inventive practice, the elastomeric coating is essentially a microparticle-filled strain-rate-sensitivity-hardening elastomeric matrix material, and the areal density of the textile-based layer does not exceed 1.7 psf. The microparticles (e.g., spherical glass microparticles) do not exceed, by weight, 30 percent of the strain-rate-sensitivity-hardening elastomeric matrix material. The textile-based layer affords ballistic protection; the elastomeric coating affords protection against sharp/pointed objects.
FILED Thursday, August 01, 2019
APPL NO 16/529477
ART UNIT 1789 — Miscellaneous Articles, Stock Material
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 31/24 (20190201)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/022 (20130101)

Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General
F41H 1/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852547 Sechrist et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Zachary A. Sechrist (Alexandria, Virginia);  Ronald J. Tonucci (Waldorf, Maryland)
ABSTRACT A sensor configured to sense when a force is applied to a surface includes a capacitive structure having a first conductive layer, a dielectric layer, and a second conductive layer. The dielectric layer is overlain on the first conductive layer and the second conductive layer is overlain on the dielectric layer. A glass superstrate has a first side and a second side, with the first side overlain on the second conductive layer. The force is applied to the second side of the glass superstrate. The force results from an object attached to the second side of the glass superstrate. The force causes capacitance changes between the first and second conductive layers. The force can be compressive or tensile, depending on whether the object is attached by magnet or adhesive.
FILED Tuesday, February 07, 2023
APPL NO 18/106586
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for
B60R 11/00 (20130101)
B60R 2011/004 (20130101)
B60R 2011/0063 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/146 (20130101) Original (OR) Class
G01L 1/148 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852605 Mirica et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Katherine A. Mirica (Hanover, New Hampshire);  Lukasz K. Mendecki (White River Junction, Vermont);  Michael Ko (West Lebanon, New Hampshire);  Zheng Meng (West Lebanon, New Hampshire);  Robert M. Stolz (Lyme, New Hampshire);  Aileen Eagleton (Hanover, New Hampshire)
ABSTRACT In some embodiments, the present disclosure pertains to methods of detecting an analyte in a sample by associating the sample with an electrode that includes a metal-organic framework. After association, the redox properties of the electrode are evaluated. Thereafter, the presence or absence of the analyte in the sample is detected by correlating the redox properties of the electrode to the presence or absence of the analyte. In some embodiments, the present disclosure pertains to electrodes that include a metal-organic framework and an electrode surface. In particular embodiments of the present disclosure, the metal-organic framework is associated with the electrode surface. Additional embodiments of the present disclosure pertain to methods of making the electrodes of the present disclosure by associating a metal-organic framework with an electrode surface. In some embodiments, the methods of the present disclosure also include a step of mixing the metal-organic framework with a polymer.
FILED Friday, June 21, 2019
APPL NO 17/252003
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 35/00 (20130101)
B82Y 40/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 1/08 (20130101)
C07F 15/04 (20130101)
C07F 15/006 (20130101)
C07F 15/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3277 (20130101)
G01N 27/3278 (20130101) Original (OR) Class
G01N 2333/575 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852765 Kirchoff et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The Government of the United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) Eric H Kirchoff (Newport, Rhode Island);  Michael J Kroger (Middletown, Rhode Island)
ABSTRACT An assembly with a first coupling having a forward bulkhead device is provided. The forward bulkhead device contains a first connector insert having first end connections for wires and optical fibers of an acoustic array. The assembly also includes a second coupling having an aft bulkhead device therein. The aft bulkhead device contains a second connector insert having second end connections for the wires and optical fibers of the acoustic array. The forward bulkhead device further includes an alignment assembly. The alignment assembly is matable with the aft bulkhead device to align the first connector insert with the second connector insert. The forward bulkhead device further includes a locking ring connecting the forward bulkhead device with the aft bulkhead device.
FILED Thursday, September 01, 2022
APPL NO 17/900941
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 21/66 (20130101)
B63B 73/00 (20200101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/186 (20130101) Original (OR) Class
G01V 1/202 (20130101)
G01V 1/3843 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11853141 Joram et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Michael P. Joram (Fredericksburg, Virginia);  Emily E. Rabin (King George, Virginia);  Bridgett M. Burg (Fredericksburg, Virginia);  Kyle S. Dalton (Fredericksburg, Virginia);  Steven H. Lohrey (Fredericksburg, Virginia);  Dominique K. James (Fredericksburg, Virginia);  Tyler M. Boitnott (Fredericksburg, Virginia)
ASSIGNEE(S) United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Michael P. Joram (Fredericksburg, Virginia);  Emily E. Rabin (King George, Virginia);  Bridgett M. Burg (Fredericksburg, Virginia);  Kyle S. Dalton (Fredericksburg, Virginia);  Steven H. Lohrey (Fredericksburg, Virginia);  Dominique K. James (Fredericksburg, Virginia);  Tyler M. Boitnott (Fredericksburg, Virginia)
ABSTRACT A computer implemented method is provided for monitoring and managing system electrical power usage. The method includes sensing component electrical usage, comparing the component usage against a corresponding lookup table, and adjusting the component usage so system power usage remains below an established threshold.
FILED Thursday, March 31, 2022
APPL NO 17/709484
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 21/06 (20130101)
G01R 22/061 (20130101)

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 15/02 (20130101)

Electric Digital Data Processing
G06F 1/3206 (20130101) Original (OR) Class

Pulse Technique
H03K 19/17728 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11853655 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) United States of America As Represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Young T. Shen (Potomac, Maryland);  Michael J. Hughes (Vienna, Virginia);  David E. Hess (Mt. Airy, Maryland)
ABSTRACT A full-scale resistance prediction for ships. More particularly, the invention is directed to full-scale resistance predictions for ships using model scale resistance tests. This process involves the designing of a momentum thickness similarity simulator for a model, to accurately determine a model resistance and ultimately to predict a ship resistance. The simulator modifies the geometry of the model, and its design is optimized to accurately predict the ship resistance. The simulator may be an external device such as a wire ring (trip wire), sand paper, or a Hama strip, or the simulator may be integrally formed on the body of the model.
FILED Tuesday, September 24, 2019
APPL NO 16/580943
ART UNIT 2146 — Computer Architecture and I/O
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 3/14 (20130101)

Electric Digital Data Processing
G06F 17/13 (20130101)
G06F 30/15 (20200101) Original (OR) Class
G06F 30/20 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11854113 Nataraj et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Mayachitra, Inc. (Santa Barbara, California)
ASSIGNEE(S) Mayachitra, Inc. (Santa Barbara, California)
INVENTOR(S) Lakshmanan Nataraj (Goleta, California);  Michael Gene Goebel (Santa Barbara, California);  Bangalore S. Manjunath (Santa Barbara, California);  Shivkumar Chandrasekaran (Santa Barbara, California)
ABSTRACT Systems and methods herein describe accessing an image, generating a resized image, generating an image feature vector by applying an image classification neural network to the resized image, generating analysis of the image by processing the image feature vector using a machine-learning classifier trained to analyze the image feature vector, and based on the analysis, determining an event that is attributed to the image.
FILED Tuesday, November 03, 2020
APPL NO 17/088132
ART UNIT 2631 — Digital Communications
CURRENT CPC
Electric Digital Data Processing
G06F 16/55 (20190101)
G06F 18/22 (20230101)
G06F 18/213 (20230101)
G06F 18/2415 (20230101)
G06F 18/2431 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 3/08 (20130101)

Image Data Processing or Generation, in General
G06T 1/0028 (20130101) Original (OR) Class
G06T 3/40 (20130101)

Image or Video Recognition or Understanding
G06V 10/764 (20220101)
G06V 20/35 (20220101)
G06V 20/44 (20220101)
G06V 30/248 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11854245 Xu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Department of Justice (DOJ)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
INVENTOR(S) Felix Juefei Xu (Pittsburgh, Pennsylvania);  Marios Savvides (Pittsburgh, Pennsylvania)
ABSTRACT The invention specifies a method of improving a subsequent iterations of a generative network by adding a ranking loss to the total loss for the network, the ranking loss representing the marginalized difference between a discriminator score for a generated image in one iteration of the generative network and the discriminator score for a real image from a subsequent iteration of the generative network.
FILED Monday, April 29, 2019
APPL NO 16/976417
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/11 (20130101)
G06F 18/22 (20230101)
G06F 18/2113 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/045 (20230101)
G06N 3/047 (20230101)
G06N 3/084 (20130101)
G06N 3/088 (20130101)
G06N 3/0455 (20230101)
G06N 3/0475 (20230101)
G06N 20/20 (20190101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101) Original (OR) Class
G06V 10/454 (20220101)
G06V 10/761 (20220101)
G06V 40/168 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11854373 Porpiglia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense MicroElectronics Activity (DMEA)
APPLICANT(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Andrew M. Porpiglia (Nashua, New Hampshire);  Kyle W. Flynn (Merrimack, New Hampshire);  Brian A. Harris (Bedford, New Hampshire);  Timothy J. O'Donnell (Bedford, New Hampshire)
ABSTRACT A system and method for combining the inputs of various sensors used in platforms, primarily those having a military use, having or making use of a number of inputs capable of determining information about an environment in which they are operating. Each input is configured to output a standardized set of information regarding its capabilities and the environment in which it is operating. A correlator is configured to adaptably process the information based on rules contained in at least one changeable correlation matrix and information contained in at least one changeable configuration file. The information, or simply an alert, is provided to at least one output that provides the information to a human operator.
FILED Wednesday, July 05, 2017
APPL NO 16/628126
ART UNIT 3619 — Selective Communication
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/726 (20130101)

Electric Digital Data Processing
G06F 17/15 (20130101)
G06F 17/16 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 26/008 (20130101)
G08B 29/02 (20130101)
G08B 29/188 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855111 Oskotsky et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Mark L. Oskotsky (Mamaroneck, New York);  Thomas Altamura (Hicksville, New York);  Daniel Engheben (Commack, New York);  Morgan Jolley (Commack, New York);  Christopher V. Lipari (Whitestone, New York);  Vincent Lipari (Whitestone, New York);  Jerry Ma (Flushing, New York);  Michael J. Russo, Jr. (Roslyn, New York);  Yueli Zhang (Saint James, New York)
ABSTRACT A Mid-Wave Infrared (MWIR) objective lens having an F # of 2.64 and a 33.6° angular field of view. It is deployed, with a focal plane and scanning system, on an airborne platform for remote sensing applications. Focal length is 9 inches, and the image is formed on a focal plane constituting CCD or CMOS with micro lenses. The lens has, from object to image, three optical element groups with a cold shield/aperture stop. Group 1 has a positive optical power and three optical elements; Group 2 has a positive optical power and four optical elements; Group 3 has a positive optical power and three optical elements. The objective lens is made of two Germanium and Silicon. The lens is both apochromatic and orthoscopic, and corrected for monochromatic and chromatic aberrations over 3.3 to 5.1 micrometers.
FILED Friday, April 23, 2021
APPL NO 17/238477
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 3/0037 (20130101)
G02B 9/12 (20130101)
G02B 13/0005 (20130101)
G02B 13/14 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/14627 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855195 Cai et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) GLOBALFOUNDRIES Singapore Pte. Ltd. (Singapore, Singapore)
ASSIGNEE(S) GLOBALFOUNDRIES SINGAPORE PTE. LTD. (Singapore, Singapore)
INVENTOR(S) Xinshu Cai (Singapore, Singapore);  Shyue Seng Tan (Singapore, Singapore);  Vibhor Jain (Williston, Vermont);  John J. Pekarik (Underhill, Vermont);  Kien Seen Daniel Chong (Singapore, Singapore);  Yung Fu Chong (Singapore, Singapore);  Judson R. Holt (Ballston Lake, New York);  Qizhi Liu (Lexington, Massachusetts);  Kenneth J. Stein (Sandy Hook, Connecticut)
ABSTRACT The present disclosure relates to semiconductor structures and, more particularly, to transistor with wrap-around extrinsic base and methods of manufacture. The structure includes: a substrate; a collector region within the substrate; an emitter region over the substrate and which comprises mono-crystal silicon based material; an intrinsic base under the emitter region and comprising semiconductor material; and an extrinsic base surrounding the emitter and over the intrinsic base.
FILED Monday, October 25, 2021
APPL NO 17/509604
ART UNIT 2821 — Optics
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/45 (20130101)
H01L 29/1004 (20130101)
H01L 29/7371 (20130101) Original (OR) Class
H01L 29/66242 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855411 Zhou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Board of Regents, The University of Texas System (USAustin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Weidong Zhou (Southlake, Texas);  Xiaochen Ge (Sugar Land, Texas)
ABSTRACT In one embodiment, a nanobeam cavity device includes an elongated waveguide having a central optical cavity, first and second lateral substrates that are positioned on opposed lateral sides of the waveguide, and carrier-injection beams that extend from the first and second lateral substrates to the central optical cavity of the elongated waveguide.
FILED Wednesday, July 07, 2021
APPL NO 17/369789
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/11 (20210101)
H01S 5/12 (20130101)
H01S 5/026 (20130101)
H01S 5/0424 (20130101) Original (OR) Class
H01S 5/1021 (20130101)
H01S 5/1042 (20130101)
H01S 5/1067 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855501 Cao
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) University of Connecticut (Farmington, Connecticut)
ASSIGNEE(S) University of Connecticut (Farmington, Connecticut)
INVENTOR(S) Yang Cao (Glastonbury, Connecticut)
ABSTRACT An insulating composition having a polymer resin, a nanoclay, and one or more nanofillers. The insulating composition has a thermal conductivity of greater than about 0.8 W/mK, a dielectric constant of less than about 5, a dissipation factor of less than about 3%, and a breakdown strength of greater than about 1,000 V/mil. The insulating composition has an endurance life of at least 400 hours at 310 volts per mil.
FILED Friday, December 09, 2022
APPL NO 18/078300
ART UNIT 2841 — Semiconductors/Memory
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 3/12 (20130101)
H01B 3/40 (20130101)
H01B 3/46 (20130101)
H01B 3/305 (20130101)
H01B 3/306 (20130101)
H01B 3/426 (20130101)
H01B 3/427 (20130101)

Dynamo-electric Machines
H02K 3/30 (20130101) Original (OR) Class
H02K 3/50 (20130101)
H02K 15/12 (20130101)
H02K 15/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855866 Soha et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) The MITRE Corporation (McLean, Virginia)
ASSIGNEE(S) The MITRE Corporation (McLean, Virginia)
INVENTOR(S) Michael James Soha (Chelmsford, Massachusetts);  Allison Inez Mann (Highland Park, New Jersey);  John Michael Zuena (Burlington, Massachusetts)
ABSTRACT Described herein are systems and methods for assessing a computing network's physical robustness to node and/or link failure during operation of the computing network. In one or more examples, the systems and methods can incorporate graph modeling and analysis techniques to assess the impact of node removal from a computing network and determine the impact that such removal has on the overall physical connectivity of the network. In one or more examples, a user or other entity can provide the system with a graph representation of a computing network, as well as specify the number of nodes to be removed (i.e., to simulate failure) to test the connectivity of the network. The system using these inputs can determine a worst-case scenario operating condition based on the inputs provided by the user, and can also assess the “network merit” which can represent a user-programmable definition that can represent a plurality desired types of connectivity.
FILED Thursday, September 29, 2022
APPL NO 17/956425
ART UNIT 2419 — Printing/Measuring and Testing
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/14 (20130101)
H04L 43/045 (20130101)
H04L 43/065 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11856000 Chen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Yunang Chen (Madison, Wisconsin);  Mohannad Alhanahnah (Madison, Wisconsin);  Andrei Sabelfeld (Hoboken, New Jersey);  Rahul Chatterjee (Madisn, Wisconsin);  Earlence Fernandes (Middleton, Wisconsin)
ABSTRACT An apparatus and method for improving the security of trigger action platforms of a type providing interoperability between computer services send the trigger service additional information about an interoperability rule for the computer services so that the trigger service may implement a minimizer reducing the data communicated when the interoperability is implemented. Implementation of the minimizer may be done in a way that is transparent to the trigger action platform eliminating the need for disruption of existing interoperability services.
FILED Friday, June 04, 2021
APPL NO 17/339273
ART UNIT 2496 — Printing/Measuring and Testing
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3247 (20130101)
H04L 63/123 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11856012 Rondeau et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Christopher M. Rondeau (Kettering, Ohio);  Michael A. Temple (Huber Heights, Ohio);  Juan Lopez, Jr. (Loudon, Tennessee);  J. Addison Betances (Beavercreek, Ohio)
ABSTRACT A method for cyber security monitor includes monitoring a network interface that is input-only configured to surreptitiously and covertly receive bit-level, physical layer communication between networked control and sensor field devices. During a training mode, a baseline distinct native attribute (DNA) fingerprint is generated for each networked field device. During a protection mode, a current DNA fingerprint is generated for each networked field device. The current DNA fingerprint is compared to the baseline DNA fingerprint for each networked field device. In response to detect at least one of RAA and PAA based on a change in the current DNA fingerprint to the baseline DNA fingerprint of one or more networked field devices, an alert is transmitted, via an external security engine interface to an external security engine.
FILED Tuesday, February 07, 2023
APPL NO 18/106533
ART UNIT 2419 — Printing/Measuring and Testing
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/145 (20130101)
H04L 63/0869 (20130101)
H04L 63/1416 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11856013 Bowman et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) The George Washington University (Washington, District of Columbia)
INVENTOR(S) Benjamin Bowman (Kensington, Maryland);  Craig Laprade (Fairfax, Virginia);  H. Howie Huang (McLean, Virginia)
ABSTRACT A system includes a log receiving module, an authentication graph module, a sampling module, an embedding module, a training module, a link prediction module, and an anomaly detection module. The log receiving module is configured to receive a first plurality of network-level authentication logs. The authentication graph module is configured to generate an authentication graph. The sampling module is configured to generate a plurality of sequences. The embedding module is configured to tune a plurality of node embeddings according to the plurality of sequences. The training module is configured to train a link predictor according to the plurality of node embeddings and ground-truth edge information from the authentication graph. The link prediction module is configured to apply the link predictor to performs a link prediction. The anomaly detection module is configured to perform anomaly detection according to the link prediction.
FILED Monday, June 29, 2020
APPL NO 16/915183
ART UNIT 2469 — Multiplex and VoIP
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/0876 (20130101)
H04L 63/1425 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11856524 El-Jamous et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) INTELLIGENT AUTOMATION, LLC (Rockville, Maryland)
ASSIGNEE(S) INTELLIGENT AUTOMATION, LLC (Rockville, Maryland)
INVENTOR(S) Ziad El-Jamous (Rockville, Maryland);  Yalin Evren Sagduyu (Gaithersburg, Maryland);  Kemal Davaslioglu (Ellicott City, Maryland)
ABSTRACT Wireless networks with plural nodes having a respective transceiver and a processor configured to, and methods to, obtain current state data, calculate a reward, store such state data and rewards in a collected parameters database, provide such current state data and data from such collected parameters database to a reinforced neural network, select an action using the reinforced neural network, and output the action to the respective transceiver so as to selective modify its transmit power level.
FILED Tuesday, December 07, 2021
APPL NO 17/544649
ART UNIT 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Wireless Communication Networks
H04W 52/06 (20130101)
H04W 52/223 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11856690 Thrasher et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Carl J. Thrasher (Huber Heights, Ohio);  Christopher E. Tabor (Kettering, Ohio);  Zachary J. Farrell (Xenia, Ohio);  Nicholas J. Morris (Dayton, Ohio)
ABSTRACT The present invention relates to substrates comprising a network comprising core shell liquid metal encapsulates comprising multi-functional ligands and processes of making and using such substrates. The core shell liquid metal particles are linked via ligands to form such network. Such networks volumetric conductivity increases under strain which maintains a substrate's resistance under strain. The constant resistance results in consistent thermal heating via resistive heating. Thus allowing a substrate that comprises such network to serve as an effective heat provider.
FILED Wednesday, July 28, 2021
APPL NO 17/386807
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/09 (20130101)
H05K 1/0283 (20130101) Original (OR) Class
H05K 3/10 (20130101)
H05K 3/22 (20130101)
H05K 2201/0245 (20130101)
H05K 2201/0314 (20130101)
H05K 2203/0783 (20130101)
H05K 2203/1105 (20130101)
H05K 2203/1131 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11850092 Lall et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S) Hybridyne Imaging Technologies, Inc. (Toronto, Canada)
ASSIGNEE(S)
INVENTOR(S) Terrence Lall (Toronto, Canada);  James A. Ionson (Lexington, Massachusetts)
ABSTRACT A dual modality endocavity imaging and treatment system for detection of cancer and targeted biopsy and treatment procedures, comprising: a housing; a nuclear detector system housed within the housing and configured for detecting nuclear radiation imaging data; an ultrasound detector system housed within the housing for detecting ultrasound imaging data; a needle associated with the housing and adjustably positionable relative thereto; and a data processing module configured to receive the nuclear radiation imaging data and the ultrasound imaging data and to generate and output an image showing the relative position of the needle and an endocavity object of interest. The needle may include a distinct radiation signature to facilitate imaging thereof.
FILED Friday, October 08, 2021
APPL NO 17/496854
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/12 (20130101)
A61B 6/037 (20130101)
A61B 6/481 (20130101)
A61B 6/482 (20130101)
A61B 6/5235 (20130101)
A61B 6/5247 (20130101)
A61B 8/12 (20130101)
A61B 8/465 (20130101)
A61B 8/0841 (20130101)
A61B 8/4416 (20130101) Original (OR) Class
A61B 8/5207 (20130101)
A61B 10/0233 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1001 (20130101)
A61N 5/1027 (20130101)
A61N 5/1049 (20130101)
A61N 5/1071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850569 Elliott et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) ExxonMobil Technology and Engineering Company (Annandale, New Jersey);  TDA Research, Inc. (Wheat Ridge, Colorado)
ASSIGNEE(S) EXXONMOBIL TECHNOLOGY AND ENGINEERING COMPANY (Annandale, New Jersey);  TDA RESEARCH, INC. (Wheat Ridge, Colorado)
INVENTOR(S) Jeannine Elizabeth Elliott (Superior, Colorado);  Robert James Copeland (Arvada, Colorado);  Margarita Dubovik (Denver, Colorado);  Daniel P. Leta (Flemington, New Jersey);  Patrick P. McCall (Matawan, New Jersey);  Chuansheng Bai (Phillipsburg, New Jersey);  Bruce A. DeRites (Pittstown, New Jersey)
ABSTRACT Compositions and methods of preparing the compositions are disclosed for sorbents and other surfaces that can adsorb and desorb carbon dioxide. A sorbent or surface can include a metal compound such as an alkali or alkaline earth compound and a support. The sorbent can be prepared by several methods, including an incipient wetness technique. The sorbents have a CO2 adsorption and desorption profile. A sorbent having high levels of a metal compound and adsorbed CO2 is disclosed.
FILED Monday, June 01, 2020
APPL NO 16/889657
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/08 (20130101)
B01J 20/20 (20130101)
B01J 20/041 (20130101)
B01J 20/043 (20130101) Original (OR) Class
B01J 20/3204 (20130101)
B01J 20/3236 (20130101)
B01J 20/3466 (20130101)
B01J 20/3483 (20130101)
B01J 20/3491 (20130101)
B01J 2220/603 (20130101)
B01J 2220/606 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 20/40 (20200801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850571 Gray et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S) United States Department of Energy (Washington, District of Columbia)
INVENTOR(S) McMahan L Gray (Pittsburgh, Pennsylvania);  Brian W. Kail (Pittsburgh, Pennsylvania);  Walter Christopher Wilfong (Clinton, Pennsylvania);  Qiuming Wang (Bridgeville, Pennsylvania);  Fan Shi (Pittsburgh, Pennsylvania)
ABSTRACT This disclosure provides polyamine sorbent compositions for the separation of metals from aqueous solutions. The polyamine sorbent compositions comprise a silica support, an aminosilane bound to the silica support, an epoxysilane bound to the silica support, and a polyamine where the polyamine is chemically tethered onto a solid silica support through via the epoxysilane. The polyamine may be further stabilized within the bulk sorbent through hydrogen bonding interactions with the aminosilane. The sorbent compositions resist leaching by H2O in an aqueous stream containing heavy oxyanion-based (and other) metals and demonstrate stability over a pH range of 2-14. The sorbent compositions are useful for the separation of metals from aqueous solutions. The cationic heavy metals are captured by the co-existing amine groups (—NH2, —NH, —N) from the polymeric network while additional metal capture capacity is derived from the introduction of a secondary silane linker.
FILED Monday, July 20, 2020
APPL NO 16/933743
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 15/08 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/103 (20130101)
B01J 20/265 (20130101) Original (OR) Class
B01J 20/3204 (20130101)
B01J 20/3219 (20130101)
B01J 20/3272 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/285 (20130101)
C02F 1/288 (20130101)
C02F 2101/22 (20130101)
C02F 2101/103 (20130101)
C02F 2101/106 (20130101)
C02F 2103/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850790 Mukherjee et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Saptarshi Mukherjee (Milpitas, California);  Tammy Chang (San Ramon, California);  Joseph W. Tringe (Walnut Creek, California)
ABSTRACT The present disclosure relates to a volumetric additive manufacturing system for forming a structure from a volume of resin using microwave energy. The system makes use of an electronic controller and at least one beam forming algorithm accessible by the electronic controller for generating information relating to an amplitude and a time delay for forming a microwave signal, where the microwave signal will be used in irradiating a build volume, and where the build volume is formed by the volume of resin. A microwave signal generating subsystem is included which is responsive to the information generated by the beam forming algorithm, and which generates a microwave signal using the amplitude and the time delay determined by the beam forming algorithm. An antenna is used to receive the microwave signal and project the microwave signal as a microwave beam, in accordance with the amplitude and time delay, into the build volume to form the structure.
FILED Wednesday, November 03, 2021
APPL NO 17/518115
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/129 (20170801) Original (OR) Class
B29C 64/241 (20170801)
B29C 64/245 (20170801)
B29C 64/264 (20170801)
B29C 64/393 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851143 Siegel
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Atargis Energy Corporation (Pueblo, Colorado)
ASSIGNEE(S) Atargis Energy Corporation (Pueblo, Colorado)
INVENTOR(S) Stefan G. Siegel (Pueblo, Colorado)
ABSTRACT A mooring system for an Ocean Wave Energy Converters (OWEC) includes multiple structural members such as legs and braces that are linearly extendible and connected using mobile joints, each joint providing two degrees of freedom for rotations about the joint. Mobile joints also attach bottom ends of the legs to mooring points. A jacking system can change lengths of the extensible structural members to adjust depth of the OWEC for operation or for storm safety, to lift the OWEC out of the water for maintenance, or to align the OWEC to an incoming wave direction.
FILED Thursday, January 14, 2021
APPL NO 17/149388
ART UNIT 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 21/502 (20130101)
B63B 35/44 (20130101) Original (OR) Class
B63B 2035/4466 (20130101)

Machines or Engines for Liquids
F03B 13/20 (20130101)

Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G
F05B 2240/97 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851334 Chen et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Gang Chen (Carlisle, Massachusetts);  Evelyn N. Wang (Cambridge, Massachusetts);  Svetlana Boriskina (Winchester, Massachusetts);  Lee A. Weinstein (Somerville, Massachusetts);  Sungwoo Yang (Chattanooga, Tennessee);  Bikramjit S. Bhatia (Cambridge, Massachusetts);  Lin Zhao (Revere, Massachusetts);  Elise M. Strobach (Clear Lake, Wisconsin);  Thomas A. Cooper (Boston, Massachusetts);  David M. Bierman (Cambridge, Massachusetts);  Xiaopeng Huang (Mountain View, California);  James Loomis (Valparaiso, Florida)
ABSTRACT A silica aerogel having a mean pore size less than 5 nm with a standard deviation of 3 nm. The silica aerogel may have greater than 95% solar-weighted transmittance at a thickness of 8 mm for wavelengths in the range of 250 nm to 2500 nm, and a 400° C. black-body weighted specific extinction coefficient of greater than 8 m2/kg for wavelengths of 1.5 μm to 15 μm. Silica aerogel synthesis methods are described. A solar thermal aerogel receiver (STAR) may include an opaque frame defining an opening, an aerogel layer disposed in the opaque frame, with at least a portion of the aerogel layer being proximate the opening, and a heat transfer fluid pipe in thermal contact with and proximate the aerogel layer. A concentrating solar energy system may include a STAR and at least one reflector to direct sunlight to an opening in the STAR.
FILED Friday, November 06, 2020
APPL NO 17/091141
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/0091 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 33/14 (20130101)
C01B 33/1585 (20130101) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2004/64 (20130101)
C01P 2006/16 (20130101)
C01P 2006/32 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 14/064 (20130101)

Solar Heat Collectors; Solar Heat Systems
F24S 10/95 (20180501)
F24S 20/20 (20180501)
F24S 23/70 (20180501)
F24S 70/20 (20180501)
F24S 80/56 (20180501)
F24S 80/65 (20180501)
F24S 2023/872 (20180501)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851350 Wang et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Yifeng Wang (Albuquerque, New Mexico);  Andy Miller (Emporia, Kansas);  Jessica N. Kruichak (Albuquerque, New Mexico);  Melissa Marie Mills (Albuquerque, New Mexico);  Hernesto Tellez (Albuquerque, New Mexico)
ABSTRACT A method for removing a contaminant from a fluid is provided. A positively charged layered double hydroxide is combined with a negatively charged clay material to form adsorption material. The adsorption material is contacted with an aqueous solution containing the contaminant to adsorb the contaminant onto the adsorption material.
FILED Wednesday, October 25, 2017
APPL NO 15/793613
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/08 (20130101)
B01J 20/12 (20130101)
B01J 20/3085 (20130101)
B01J 39/02 (20130101)
B01J 41/02 (20130101)
B01J 43/00 (20130101)
B01J 47/00 (20130101)
B01J 2220/42 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/281 (20130101)
C02F 1/288 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851384 Ramasamy et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington);  LanzaTech, Inc. (Skokie, Illinois)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington);  Lanzatech, Inc. (Skokie, Illinois)
INVENTOR(S) Karthikeyan K. Ramasamy (West Richland, Washington);  Mond Guo (Richland, Washington);  Richard Russell Rosin (Glencoe, Illinois);  Joseph Anthony Kocal (Glenview, Illinois)
ABSTRACT Disclosed herein are embodiments of a method and system for converting ethanol to para-xylene. The method also provides a pathway to produce terephthalic acid from biomass-based feedstocks. In some embodiments, the disclosed method produces p-xylene with high selectivity over other aromatics typically produced in the conversion of ethanol to xylenes, such as m-xylene, ethyl benzene, benzene, toluene, and the like. And, in some embodiments, the method facilitates the ability to use ortho/para mixtures of methylbenzyaldehyde for preparing ortho/para xylene product mixtures that are amendable to fractionation to separate the para- and ortho-xylene products thereby providing a pure feedstock of para-xylene that can be used to form terephthalic anhydride and a pure feedstock of ortho-xylene that can be used for other purposes, such as phthalic anhydride.
FILED Tuesday, April 05, 2022
APPL NO 17/713686
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 1/2076 (20130101) Original (OR) Class
C07C 7/04 (20130101)
C07C 45/68 (20130101)
C07C 2521/04 (20130101)
C07C 2521/06 (20130101)
C07C 2521/18 (20130101)
C07C 2523/44 (20130101)
C07C 2523/656 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851416 Coates et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Geoffrey W. Coates (Lansing, New York);  Jessica Rachel Lamb (Cambridge, Massachusetts);  Kristine Klimovica (St. Paul, Minnesota);  Aran Kathleen Hubbell (Ithaca, New York)
ABSTRACT Provided are methods of producing carbonyl compounds (e.g., carbonyl containing compounds) and catalysts for producing carbonyl compounds. Also provided are methods of making polymers from carbonyl compounds and polymers formed from carbonyl compounds. A method may produce carbonyl compounds, such as, for example α,α-disubstituted carbonyl compounds (e.g., α,α-disubstituted β-lactones). The polymers may be produced from α,α-disubstituted β-lactones, which may be produced by a method described herein.
FILED Wednesday, July 22, 2020
APPL NO 16/936322
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/184 (20130101)
B01J 31/1825 (20130101)
B01J 2231/34 (20130101)
B01J 2531/31 (20130101)

Acyclic or Carbocyclic Compounds
C07C 45/58 (20130101)

Heterocyclic Compounds
C07D 305/12 (20130101) Original (OR) Class

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/069 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/08 (20130101)
C08G 63/84 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851450 Even
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Dakota Even (Overland Park, Kansas)
ABSTRACT A method for forming monosubstituted diphenylsilanes is broadly provided. The method involves reacting diphenylsilane with an alcohol in the presence of a catalyst and a strong base activator. The reaction results in high selectivity to addition at only one hydrogen site.
FILED Wednesday, November 17, 2021
APPL NO 17/528747
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 31/2273 (20130101)
B01J 2531/16 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/0874 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851543 Bulger et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California)
ASSIGNEE(S) XEROX CORPORATION (Norwalk, Connecticut)
INVENTOR(S) Eli Bulger (Nottawa, Canada);  Mahati Chintapalli (Mountain View, California);  Gabriel Iftime (Dublin, California);  Quentin Van Overmeere (Mountain View, California);  Jessica Louis Baker Rivest (Palo Alto, California);  Ravi Neelakantan (Redwood City, California);  Stephen Meckler (Redwood City, California)
ABSTRACT A method of producing a polymer aerogel includes dissolving precursors into a solvent, wherein the precursors include monomers, crosslinkers, a controlling agent and an initiator to form a precursor solution, wherein at least one of the monomers or at least one of the crosslinkers has a refractive index of 1.5 or lower, polymerizing the precursor solution to form a gel polymer, and removing the solvent from the gel polymer to produce the polymer aerogel. A method of producing a polymer aerogel include dissolving precursors into a solvent, wherein the precursors include monomers, crosslinkers, a controlling agent and an initiator to form a precursor solution, polymerizing the precursor solution to form a gel polymer, removing the solvent from the gel polymer to produce the polymer aerogel, and reducing a refractive index of one of either the gel polymer or the polymer aerogel.
FILED Friday, April 30, 2021
APPL NO 17/245418
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/242 (20130101)
C08J 9/0004 (20130101) Original (OR) Class
C08J 9/286 (20130101)
C08J 2205/026 (20130101)
C08J 2205/044 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/0025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851545 Compton et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
ASSIGNEE(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Brett Gibson Compton (Knoxville, Tennessee);  Samantha Maness (Knoxville, Tennessee);  Robert Pack (Knoxville, Tennessee);  Madeline Wimmer (Maryville, Tennessee)
ABSTRACT An ink formulation for additive manufacturing of low density syntactic foams is described. The ink formulation can include a thermoset resin, a curing agent suitable for use with the thermoset resin, a plurality of hollow spheres, such as glass microballoons, one or more solvents, and one or more non-hollow, viscosity modifying filler. Also described are a method of preparing the ink formulation, a method of preparing three-dimensional objects comprising low density syntactic foams, and the three-dimensional objects prepared thereby.
FILED Monday, August 17, 2020
APPL NO 16/995333
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/118 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2063/00 (20130101)
B29K 2101/10 (20130101)
B29K 2105/04 (20130101)
B29K 2105/165 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/10 (20200101)
B33Y 80/00 (20141201)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 9/28 (20130101) Original (OR) Class
C08J 2201/0502 (20130101)
C08J 2363/00 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/346 (20130101)
C08K 7/28 (20130101)
C08K 2201/011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851651 Banal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) James Banal (Cambridge, Massachusetts);  Joseph Don Berleant (Cambridge, Massachusetts);  Tyson Shepherd (Arlington, Massachusetts);  Mark Bathe (Cambridge, Massachusetts)
ABSTRACT Methods for the automated template-free synthesis of user-defined sequence controlled biopolymers using microfluidic devices are described. The methods facilitate simultaneous synthesis of up to thousands of uniquely addressed biopolymers from the controlled movement and combination of regents as fluid droplets using microfluidic and EWOD-based systems. In some forms, biopolymers including nucleic acids, peptides, carbohydrates, and lipids are synthesized from step-wise assembly of building blocks based on a user-defined sequence of droplet movements. In some forms, the methods synthesize uniquely addressed nucleic acids of up to 1,000 nucleotides in length. Methods for adding, removing and changing barcodes on biopolymers are also provided. Biopolymers synthesized according to the methods, and libraries and databases thereof are also described. Modified biopolymers, including chemically modified nucleotides and biopolymers conjugated to other molecules are described.
FILED Tuesday, June 19, 2018
APPL NO 16/012583
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101)
B01J 2219/0065 (20130101)
B01J 2219/00675 (20130101)
B01J 2219/00722 (20130101)
B01J 2219/00725 (20130101)
B01J 2219/00729 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502784 (20130101)
B01L 3/502792 (20130101)
B01L 2400/0427 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1068 (20130101) Original (OR) Class
C12N 15/1093 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6811 (20130101)
C12Q 2565/629 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 35/00 (20190201)
G16B 40/00 (20190201)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/60 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851686 Clarke et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Industrial Microbes, Inc. (Alameda, California)
ASSIGNEE(S) Industrial Microbes, Inc. (Alameda, California)
INVENTOR(S) Elizabeth Jane Clarke (San Francisco, California);  Derek Lorin Greenfield (Kensington, California);  Noah Charles Helman (El Cerrito, California);  Stephanie Rhianon Jones (Berkeley, California);  Baolong Zhu (Johnston, Iowa)
ABSTRACT Improved soluble methane monooxygenases and soluble methane monooxygenase systems are provided.
FILED Monday, August 30, 2021
APPL NO 17/461102
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0073 (20130101) Original (OR) Class
C12N 15/70 (20130101)
C12N 15/75 (20130101)
C12N 15/77 (20130101)

Enzymes
C12Y 114/13025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851731 Bez et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Henrique Neves Bez (Santa Catarina, Brazil);  Anis Biswas (Ames, Iowa);  Arjun K. Pathak (Ames, Iowa);  Yaroslav Mudryk (Ames, Iowa);  Nikolai A. Zarkevich (Ames, Iowa);  Viktor Balema (Ames, Iowa);  Vitalij K Pecharsky (Ames, Iowa)
ABSTRACT A method is provided of making a magnetocaloric alloy composition comprising Ni, Co, Mn, and Ti, which preferably includes certain beneficial substitutional elements, by melting the composition and rapidly solidifying the melted composition at a cooling rate of at least 100 K/second (Kelvin/second) to improve a magnetocaloric property of the composition. The rapidly solidified composition can be heat treated to homogenize the composition and annealed to tune the magneto-structural transition for use in a regenerator.
FILED Thursday, December 20, 2018
APPL NO 16/350728
ART UNIT 1738 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 8/1211 (20130101)

Alloys
C22C 1/02 (20130101)
C22C 1/023 (20130101) Original (OR) Class
C22C 1/0433 (20130101)
C22C 19/03 (20130101)
C22C 19/005 (20130101)
C22C 30/00 (20130101)
C22C 30/02 (20130101)
C22C 30/06 (20130101)
C22C 2202/02 (20130101)

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/10 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851757 Mane et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Anil U. Mane (Naperville, Illinois);  Yuepeng Zhang (Naperville, Illinois);  Devika Choudhury (Naperville, Illinois);  Jeffrey W. Elam (Elmhurst, Illinois);  Kaizhong Gao (North Oaks, Minnesota);  John N. Hryn (Hawthorn Woods, Illinois)
ABSTRACT Coated nanofibers and methods for forming the same. A magnetic nanofiber is formed and a barrier coating is deposited on the magnetic nanofiber by atomic layer deposition (“ALD”) process. The coated nanofiber may include a reduced magnetic nanostructure and a barrier coating comprising a first oxide coating on the nanofiber, the coating being non-reactive with the magnetic polymer nanofiber, the barrier coating have a thickness of 2 nm to 12 nm.
FILED Thursday, January 30, 2020
APPL NO 16/776702
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/16 (20220101)
B22F 1/0547 (20220101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 25/00 (20130101)
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/08 (20130101)
C23C 16/403 (20130101)
C23C 16/45525 (20130101)
C23C 16/45555 (20130101) Original (OR) Class

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/003 (20130101)

Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads
D02G 3/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852261 Parish et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Flowserve Pte. Ltd. (Singapore, Singapore)
ASSIGNEE(S) Flowserve Pte. Ltd. (Singapore, Singapore)
INVENTOR(S) Paul Jeffrey Parish (Spanish Fork, Utah);  Michael P. Nelson (Lehi, Utah);  Ivica Radman (Kaernten, Austria)
ABSTRACT A valve includes at least one valve stem seal, such as a packing seal, that is included in a removable seal cartridge. The valve stem is connected to the actuator via a linkage, which can be removed to provide a linkage gap between the actuator and the valve stem. The seal cartridge can then be slid along the valve stem into the linkage gap and laterally removed from the valve, whereupon the seals within the seal cartridge can be refurbished. The valve can be a rotary or linear valve. In embodiments, the linkage gap can be increased by linear displacement of the actuator away from the valve stem. The seal cartridge can be re-installed in the valve after refurbishment, or a substantially identical replacement seal cartridge can be provided, and can be installed in the valve in replacement of the removed seal cartridge, thereby minimizing downtime of the valve.
FILED Monday, September 27, 2021
APPL NO 17/485678
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 1/36 (20130101)
F16K 1/46 (20130101)
F16K 1/422 (20130101)
F16K 41/02 (20130101) Original (OR) Class
F16K 41/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852596 Klein
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Boulder Environmental Sciences and Technology (Boulder, Colorado)
ASSIGNEE(S) Boulder Environmental Sciences and Technology (Boulder, Colorado)
INVENTOR(S) Marian Klein (Boulder, Colorado)
ABSTRACT A system for passive microwave remote sensing using at least one microwave radiometer includes a fixed body portion, the fixed body portion being configured to attach to a mobile platform, and a mobile body portion, the mobile body portion being configured for rotatably coupling with the fixed body portion for rotation about a rotation axis. The mobile body portion is configured for supporting the at least one microwave radiometer therein such that the at least one microwave radiometer rotates about the rotation axis when the mobile body portion is rotated about the rotation axis such that a polarization axis of the at least one radiometer is aligned with an earth axis. The fixed body portion includes a motor mechanism for effecting rotation of the mobile body portion such that the at least one microwave radiometer provides a vertical scanning below and above the mobile platform.
FILED Wednesday, December 21, 2022
APPL NO 18/085710
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 11/006 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 22/00 (20130101)
G01N 22/04 (20130101) Original (OR) Class
G01N 33/2823 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 25/04 (20130101)
G01R 27/04 (20130101)
G01R 27/22 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852598 Aguiar
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Jeffery A. Aguiar (Salt Lake City, Utah)
ABSTRACT A material identification system includes one or more data interfaces configured to receive first sensor data generated by a first sensor responsive to a material sample, and receive second sensor data generated by a second sensor responsive to the material sample. The material identification system also includes one or more processors configured to generate a set of predictions of an identification of the material sample and a corresponding set of certainty information.
FILED Wednesday, October 23, 2019
APPL NO 17/309074
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/20058 (20130101) Original (OR) Class
G01N 2223/418 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 37/28 (20130101)
H01J 2237/2802 (20130101)
H01J 2237/2804 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852654 Moheimani et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Seyed Omid Reza Moheimani (Allen, Texas);  Mohammad Mahdavi (Dallas, Texas)
ABSTRACT Illustrative embodiments provide an apparatus comprising a substrate comprising a cantilever, a bottom electrode on the substrate, a bottom piezoelectric transducer on the bottom electrode such that the bottom electrode is between the substrate and the bottom piezoelectric transducer, a middle electrode on the bottom piezoelectric transducer such that the bottom piezoelectric transducer is between the bottom electrode and the middle electrode, a top piezoelectric transducer on the middle electrode such that the middle electrode is between the bottom piezoelectric transducer and the top piezoelectric transducer, and a top electrode on the top piezoelectric transducer, such that the top piezoelectric transducer is between the middle electrode and the top electrode. Illustrative embodiments also provide a method of making the apparatus and a method of using the apparatus for atomic force microscopy.
FILED Friday, July 17, 2020
APPL NO 16/932161
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 10/045 (20130101) Original (OR) Class
G01Q 20/04 (20130101)
G01Q 60/38 (20130101)

Electric solid-state devices not otherwise provided for
H10N 30/306 (20230201)
H10N 30/872 (20230201)
H10N 30/877 (20230201)
H10N 30/1071 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852764 Hayward
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S) Allen D. Hayward (Los Alamos, New Mexico)
ABSTRACT A seismic switch (SS) that is able to detect and signal when internal faults have occurred within the SS is described. The SS provides safety class functionality to the detection of seismic activity. For example, the SS may detect earthquakes above a specified level, resulting in the disconnection of electrical power to a radioactive waste storage facility, which could result in the ignition of waste materials should the storage facility and/or storage container fail during a seismic event. By reducing the risk of fire under these circumstances, the possibility of offsite releases is significantly reduced.
FILED Friday, July 26, 2019
APPL NO 16/522916
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 1/02 (20130101)
G01K 13/00 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 1/008 (20130101)
G01V 1/28 (20130101)
G01V 1/164 (20130101) Original (OR) Class
G01V 1/181 (20130101)
G01V 1/226 (20130101)
G01V 2210/14 (20130101)
G01V 2210/72 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 5/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11854669 Bachand et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) George Bachand (Albuquerque, New Mexico);  Marlene Bachand (Albuquerque, New Mexico);  Andrew Gomez (Edgewood, New Mexico)
ABSTRACT The present invention relates to method for storing and transmitting information by employing a nucleic acid construct. The nucleic acid construct can include a lock region; a translation key region that corresponds to the identity of a key; and a message region including a nucleic sequence that corresponds to an encrypted message.
FILED Tuesday, July 16, 2019
APPL NO 16/512577
ART UNIT 1671 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 50/40 (20190201) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0866 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855061 Wilkerson et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Brett P. Wilkerson (Austin, Texas);  Milind S. Bhagavat (Cupertino, California);  Rahul Agarwal (San Francisco, California);  Dmitri Yudanov (Austin, Texas)
ABSTRACT A three-dimensional integrated circuit includes a first die structure having a first geometry. The first die structure includes a first region that operates with a first power density and a second region that operates with a second power density. The first power density is less than the second power density. The three-dimensional integrated circuit includes a second die structure having a second geometry. A stacked portion of the second die structure is aligned with the first region. The three-dimensional integrated circuit includes an additional die structure stacked with the first die structure and the second die structure. The additional die structure has the first geometry or the second geometry.
FILED Friday, August 19, 2022
APPL NO 17/891444
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/481 (20130101)
H01L 23/3675 (20130101)
H01L 24/03 (20130101)
H01L 24/05 (20130101)
H01L 24/06 (20130101)
H01L 24/08 (20130101)
H01L 24/09 (20130101)
H01L 25/18 (20130101) Original (OR) Class
H01L 25/50 (20130101)
H01L 2224/0557 (20130101)
H01L 2224/03002 (20130101)
H01L 2224/06179 (20130101)
H01L 2224/06181 (20130101)
H01L 2224/08146 (20130101)
H01L 2224/09179 (20130101)
H01L 2924/1431 (20130101)
H01L 2924/1433 (20130101)
H01L 2924/1434 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855264 Mueller et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Jacob Mueller (Albuquerque, New Mexico);  Yuliya Preger (Albuquerque, New Mexico);  John C. Hewson (Albuquerque, New Mexico);  Andrew Kurzawski (Albuquerque, New Mexico)
ABSTRACT A method and system for dispersing stored energy in an energy storage system to delay or arrest propagation of thermal runaway and thermally-induced cascading failures. The system includes a plurality of battery sub-assemblies and DC-DC converters connected to a shared DC bus through which energy may be exchanged. The system may be interfaced to an AC power grid or DC power system through an additional power converter. The method of dispersing stored energy uses this system to charge and discharge sub-assemblies such that the system is less susceptible to propagation of thermal runaway. The method determines, based on awareness of current system state, battery types, and electrical and thermal structure, the sequence of charging and discharging actions to best inhibit thermal runaway while preserving the system's ability to perform subsequent energy redistribution.
FILED Friday, January 08, 2021
APPL NO 17/144681
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/425 (20130101)
H01M 10/441 (20130101)
H01M 10/443 (20130101) Original (OR) Class
H01M 10/482 (20130101)
H01M 2010/4271 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/007 (20130101)
H02J 2207/20 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855265 Van Tassell et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) LIMINAL INSIGHTS, INC. (Emeryville, California)
ASSIGNEE(S) LIMINAL INSIGHTS, INC. (Emeryville, California)
INVENTOR(S) Barry J. Van Tassell (El Cerrito, California);  Shan Dou (Berkeley, California);  Shaurjo Biswas (El Cerrito, California);  Andrew G. Hsieh (Berkeley, California);  Andrew M. Raphael (El Cerrito, California)
ABSTRACT Systems and methods for acoustic signal based analysis, include obtaining acoustic response signal data of at least a portion of a battery cell, the acoustic response signal data comprising waveforms generated by transmitting one or more acoustic excitation signals into at least the portion of the battery cell and recording response vibration signals to the one or more acoustic excitation signals. One or more metrics are determined from at least the acoustic response signal data, the one or more metrics being determined based on correlation of the one or more metrics to one or more characteristics of battery cells and a reference model is generated from the one or more metrics. A test battery can be evaluated using the reference model. Actionable insights or recommendations can be generated based on the evaluation. The reference model can also be updated based on the evaluation.
FILED Friday, December 04, 2020
APPL NO 17/112756
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/14 (20130101)
G01N 29/024 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/392 (20190101)

Transmission Systems for Measured Values, Control or Similar Signals
G08C 17/02 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/484 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855279 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Amprius Technologies, Inc. (Fremont, California)
ASSIGNEE(S) Amprius Technologies, Inc. (Fremont, California)
INVENTOR(S) Weijie Wang (Sunnyvale, California);  Zuqin Liu (Sunnyvale, California);  Song Han (Foster City, California);  Jonathan Bornstein (Cupertino, California);  Constantin Ionel Stefan (San Jose, California)
ABSTRACT Provided herein are nanostructures for lithium ion battery electrodes and methods of fabrication. In some embodiments, a nanostructure template coated with a silicon coating is provided. The silicon coating may include a non-conformal, more porous layer and a conformal, denser layer on the non-conformal, more porous layer. In some embodiments, two different deposition processes, e.g., a PECVD layer to deposit the non-conformal layer and a thermal CVD process to deposit the conformal layer, are used. Anodes including the nanostructures have longer cycle lifetimes than anodes made using either a PECVD or thermal CVD method alone.
FILED Thursday, November 11, 2021
APPL NO 17/524206
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/134 (20130101)
H01M 4/366 (20130101)
H01M 4/386 (20130101) Original (OR) Class
H01M 4/0428 (20130101)
H01M 4/1395 (20130101)
H01M 10/052 (20130101)
H01M 10/0525 (20130101)
H01M 2004/027 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855280 Yushin et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Sila Nanotechnologies, Inc. (Alameda, California)
ASSIGNEE(S) SILA NANOTECHNOLOGIES, INC. (Alameda, California)
INVENTOR(S) Gleb Yushin (Atlanta, Georgia);  Eugene Michael Berdichevsky (Alameda, California);  Alexander Thomas Jacobs (Atlanta, Georgia);  Alper Nese (Alameda, California);  Damian Harris (San Francisco, California);  Bogdan Zdyrko (Atlanta, Georgia)
ABSTRACT Battery electrode compositions and methods of fabrication are provided that utilize composite particles. Each of the composite particles may comprise, for example, a high-capacity active material and a porous, electrically-conductive scaffolding matrix material. The active material may store and release ions during battery operation, and may exhibit (i) a specific capacity of at least 220 mAh/g as a cathode active material or (ii) a specific capacity of at least 400 mAh/g as an anode active material. The active material may be disposed in the pores of the scaffolding matrix material. According to various designs, each composite particle may exhibit at least one material property that changes from the center to the perimeter of the scaffolding matrix material.
FILED Friday, January 13, 2023
APPL NO 18/154368
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/13 (20130101)
H01M 4/362 (20130101)
H01M 4/386 (20130101)
H01M 4/388 (20130101) Original (OR) Class
H01M 4/0402 (20130101)
H01M 4/625 (20130101)
H01M 10/0525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855281 Huang
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Ge Solartech, LLC (Troy, Michigan)
ASSIGNEE(S) Ge Solartech, LLC (Troy, Michigan)
INVENTOR(S) Baoquan Huang (Troy, Michigan)
ABSTRACT The present disclosure provides methods for producing cathode materials for lithium ion batteries. Cathode materials that contain manganese are emphasized. Representative materials include LixNi1−y−zMnyCozO2 (NMC) (where x is in the range from 0.80 to 1.3, y is in the range from 0.01 to 0.5, and z is in the range from 0.01 to 0.5), LixMn2O4 (LM), and LixNi1−yMnyO2 (LMN) (where x is in the range from 0.8 to 1.3 and y is in the range from 0.0 to 0.8). The process includes reactions of carboxylate precursors of nickel, manganese, and/or cobalt and lithiation with a lithium precursor. The carboxylate precursors are made from reactions of pure metals or metal compounds with carboxylic acids. The manganese precursor contains bivalent manganese and the process controls the oxidation state of manganese to avoid formation of higher oxidation states of manganese.
FILED Saturday, March 12, 2022
APPL NO 17/693330
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium
C01D 15/02 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/485 (20130101)
H01M 4/505 (20130101) Original (OR) Class
H01M 4/525 (20130101)
H01M 10/0525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855312 Evans et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) ESS TECH, INC. (Wilsonville, Oregon)
ASSIGNEE(S) ESS TECH, INC. (Wilsonville, Oregon)
INVENTOR(S) Craig E. Evans (West Linn, Oregon);  Sean Casey (Portland, Oregon);  Yang Song (West Linn, Oregon)
ABSTRACT A redox flow battery may include: a membrane interposed between a first electrode positioned at a first side of the membrane and a second electrode positioned at a second side of the membrane opposite to the first side; a first flow field plate comprising a plurality of positive flow field ribs, each of the plurality of positive flow field ribs contacting the first electrode at first supporting regions on the first side; and the second electrode, including an electrode spacer positioned between the membrane and a second flow field plate, the electrode spacer comprising a plurality of main ribs, each of the plurality of main ribs contacting the second flow field plate at second supporting regions on the second side, each of the second supporting regions aligned opposite to one of the plurality of first supporting regions. As such, a current density distribution at a plating surface may be reduced.
FILED Friday, March 04, 2022
APPL NO 17/653620
ART UNIT 1751 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/8803 (20130101)
H01M 4/8817 (20130101)
H01M 4/8828 (20130101)
H01M 8/20 (20130101)
H01M 8/188 (20130101)
H01M 8/0239 (20130101)
H01M 8/0245 (20130101)
H01M 8/0258 (20130101) Original (OR) Class

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855348 Kamali et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Seyedeh Mahsa Kamali (Arcadia, California);  Ehsan Arbabi (Arcadia, California);  Andrei Faraon (La Canada Flintridge, California)
ABSTRACT Cascaded metasurfaces can control the phase, amplitude and polarization of an electromagnetic beam, shaping it in three dimensional configuration not achievable with other methods. Each cascaded metasurface has dielectric or metallic scatterers arranged in a period array. The shape of the scatterers determines the three dimensional configuration of the output beam and is determined with iterative calculations through computational simulations.
FILED Friday, June 17, 2022
APPL NO 17/843302
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 5/3083 (20130101)
G02B 27/0012 (20130101)
G02B 27/44 (20130101)
G02B 27/0944 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/00 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/70408 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/422 (20130101)
H01Q 1/425 (20130101)
H01Q 15/242 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855553 Mekonnen et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Imagen Energy, LLC (Wauwatosa, Wisconsin)
ASSIGNEE(S) Imagen Energy, LLC (Wauwatosa, Wisconsin)
INVENTOR(S) Ezana T Mekonnen (Oak Creek, Wisconsin);  Adel Nasiri (Lexington, South Carolina);  Jerry D. Thunes (Greenfield, Wisconsin)
ABSTRACT Provided is a novel multi-level inverter with mixed device types and methods of controlling same. This novel multi-level inverter topology and control method allows the use of high frequency switching devices for controlled PWM switching, while also using lower frequency switching devices for directional switches. This combination of high frequency PWM switching devices with low frequency directional switching devices allows a cost reduction without a significant performance degradation.
FILED Friday, January 13, 2023
APPL NO 18/097082
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/385 (20210501)
H02M 7/4835 (20210501) Original (OR) Class
H02M 7/53871 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855697 Passian
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Ali Passian (Oak Ridge, Tennessee)
ABSTRACT A system senses analytes through one or more sensors that detect or measure a physical characteristic. The one or more sensor generate a spectroscopic-data signal corresponding to the detection. An edge device communicatively couples the one or more sensors that communicatively couples a wide-area network coupling a cloud service. The edge device includes a data acquisition device that receives spectroscopic data signals from the one or more sensor and a processor that processes the spectroscopic-data signals to identify an analyte. The edge device also includes a transceiver that transmits data identifying the analytes to the cloud service.
FILED Wednesday, July 21, 2021
APPL NO 17/381826
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/65 (20130101)
G01N 21/636 (20130101)

Transmission
H04B 10/27 (20130101)
H04B 10/5057 (20130101) Original (OR) Class

Wireless Communication Networks
H04W 84/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11850327 Guiney et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Linda M. Guiney (Chicago, Illinois);  Nikhita D. Mansukhani (Libertyville, Illinois);  Adam E. Jakus (Chicago, Illinois);  Ramille N. Shah (Hinsdale, Illinois);  Mark C. Hersam (Wilmette, Illinois)
ABSTRACT Thermal management composites and scaffolds for heat-generating implantable electronic devices made from the thermal management composites are provided. The composite materials are cytocompatible, porous materials that include hexagonal boron nitride particles dispersed in an elastomeric polymer binder.
FILED Tuesday, April 30, 2019
APPL NO 17/049281
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/50 (20130101)
A61L 27/446 (20130101) Original (OR) Class

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/14276 (20130101)
A61M 2205/3633 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/37512 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 70/10 (20200101)
B33Y 80/00 (20141201)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/38 (20130101)
C08K 2003/385 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 1/10 (20130101)
D01F 6/84 (20130101)
D01F 6/92 (20130101)
D01F 6/625 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850441 Hong et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Maryland, Baltimore (Baltimore, Maryland);  University of Maryland, Baltimore County (Baltimore, Maryland)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland);  University of Maryland, Baltimore County (Baltimore, Maryland)
INVENTOR(S) L. Elliot Hong (Ellicott City, Maryland);  Fow-Sen Choa (Ellicott City, Maryland);  Qinglei Meng (Catonsville, Maryland)
ABSTRACT Disclosed is an electromagnetic coil system for use during transcranial or transdermal stimulation procedures, in which an electrically conductive coil wraps around a magnetic core at an oblique wrapping angle to provide a more directed focal spot size at a given depth inside of, for example, a patient's body. In certain configurations, the electrically conductive coil may be adjustable with respect to the magnetic core, such that the wrapping angle of the electrically conductive coil may be modified to, in turn, adjust the focal spot size of the induced electric field generated by the system as may desired to concentrate the field at a particularly desired location.
FILED Friday, January 10, 2020
APPL NO 16/739650
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 2/02 (20130101) Original (OR) Class
A61N 2/004 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 7/20 (20130101)
H01F 27/28 (20130101)
H01F 27/255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11850639 Campanella et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Loci Controls, Inc. (Wareham, Massachusetts)
ASSIGNEE(S) Loci Controls, Inc. (Wareham, Massachusetts)
INVENTOR(S) Andrew Campanella (Somerville, Massachusetts);  Joseph G. Michels (New York, New York);  Peter Quigley (Duxbury, Massachusetts);  Ian Martin (Sharon, Massachusetts)
ABSTRACT A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas.
FILED Thursday, June 01, 2023
APPL NO 18/327694
ART UNIT 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Disposal of Solid Waste
B09B 1/006 (20130101) Original (OR) Class

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851320 Sim et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Gi-Dong Sim (Elkridge, Maryland);  Jessica Krogstad (Champaign, Illinois);  Timothy P. Weihs (Baltimore, Maryland);  Kevin J. Hemker (Reisterstown, Maryland);  Gianna Valentino (Baltimore, Maryland)
ABSTRACT The present invention is directed to the synthesis of metallic nickel-molybdenum-tungsten films and coatings with direct current sputter deposition, which results in fully-dense crystallographically textured films that are filled with nano-scale faults and twins. The as-deposited films exhibit linear-elastic mechanical behavior and tensile strengths above 2.5 GPa, which is unprecedented for materials that are compatible with wafer-level device fabrication processes. The ultra-high strength is attributed to a combination of solid solution strengthening and the presence of the dense nano-scale faults and twins. These films also possess excellent thermal and mechanical stability, high density, low CTE, and electrical properties that are attractive for next generation metal MEMS applications. Deposited as coatings these films provide protection against friction and wear. The as-deposited films can also be heat treated to modify the internal microstructure and attendant mechanical properties in a way that provides a desired balance of strength and toughness.
FILED Tuesday, May 01, 2018
APPL NO 16/609968
ART UNIT 2896 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 3/0075 (20130101) Original (OR) Class
B81B 2203/0118 (20130101)

Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00674 (20130101)
B81C 2201/0132 (20130101)
B81C 2201/0133 (20130101)
B81C 2201/0181 (20130101)
B81C 2201/0197 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/18 (20130101)
C23C 14/5806 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/562 (20130101)
C25D 5/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851337 Gounder et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
ASSIGNEE(S) PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana)
INVENTOR(S) Rajamani Gounder (West Lafayette, Indiana);  Claire Townsend Nimlos (Lakewood, Colorado);  Byung Jin Lee (Seoul, South Korea)
ABSTRACT An oligomerization catalyst, oligomer products, methods for making and using same. The catalyst is synthesized MFI zeolite (ZSM-5) made from a combination of DABCO and methylamine (MEA) in the presence of Na cations.
FILED Tuesday, August 31, 2021
APPL NO 17/462597
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 39/48 (20130101) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2006/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851374 Akono et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Ange-Therese Akono (Evanston, Illinois);  Jiaxin Chen (Evanston, Illinois)
ABSTRACT Methods for the dispersion and synthesis of multi-walled carbon nanotube-cement composites with high concentrations of multi-walled carbon nanotubes that do not require chemical dispersion aids or dispersion-enhancing chemical surface functionalization are provided. Also provided are multi-walled carbon nanotube-cement composites made using the methods. Methods for the dispersion and synthesis of carbon nanofiber-cement composites with high concentrations of carbon nanofibers that do not require chemical dispersion aids or dispersion-enhancing chemical surface functionalization are further provided. Also provided are carbon nanofiber-cement composites made using the methods.
FILED Thursday, July 15, 2021
APPL NO 17/376426
ART UNIT 1738 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 14/026 (20130101)
C04B 14/386 (20130101)
C04B 28/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851651 Banal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) James Banal (Cambridge, Massachusetts);  Joseph Don Berleant (Cambridge, Massachusetts);  Tyson Shepherd (Arlington, Massachusetts);  Mark Bathe (Cambridge, Massachusetts)
ABSTRACT Methods for the automated template-free synthesis of user-defined sequence controlled biopolymers using microfluidic devices are described. The methods facilitate simultaneous synthesis of up to thousands of uniquely addressed biopolymers from the controlled movement and combination of regents as fluid droplets using microfluidic and EWOD-based systems. In some forms, biopolymers including nucleic acids, peptides, carbohydrates, and lipids are synthesized from step-wise assembly of building blocks based on a user-defined sequence of droplet movements. In some forms, the methods synthesize uniquely addressed nucleic acids of up to 1,000 nucleotides in length. Methods for adding, removing and changing barcodes on biopolymers are also provided. Biopolymers synthesized according to the methods, and libraries and databases thereof are also described. Modified biopolymers, including chemically modified nucleotides and biopolymers conjugated to other molecules are described.
FILED Tuesday, June 19, 2018
APPL NO 16/012583
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101)
B01J 2219/0065 (20130101)
B01J 2219/00675 (20130101)
B01J 2219/00722 (20130101)
B01J 2219/00725 (20130101)
B01J 2219/00729 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502784 (20130101)
B01L 3/502792 (20130101)
B01L 2400/0427 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1068 (20130101) Original (OR) Class
C12N 15/1093 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6811 (20130101)
C12Q 2565/629 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 35/00 (20190201)
G16B 40/00 (20190201)

Computational Chemistry; Chemoinformatics; Computational Materials Science
G16C 20/60 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852210 Chen et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Brigham Young University (BYU) (Provo, Utah)
ASSIGNEE(S) Brigham Young University (Provo, Utah)
INVENTOR(S) Guimin Chen (Provo, Utah);  Larry Howell (Orem, Utah);  Spencer Magleby (Provo, Utah)
ABSTRACT A lamina emergent torsional (LET) joint that includes an integrated membrane to reduce, or eliminate, certain unwanted motions and/or displacements associated with the operation of the LET joint is disclosed. The membrane-integrated LET joint (i.e., M-LET) can be used as a hinge for a lamina emergent mechanism and/or as a surrogate fold for an origami application to ensure accurate and repeatable transitions from a planar (i.e., lamina) state to a non-planar (i.e., lamina-emergent) state, and vice versa.
FILED Thursday, November 17, 2022
APPL NO 18/056522
ART UNIT 3632 — Static Structures, Supports and Furniture
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 1/027 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852596 Klein
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Boulder Environmental Sciences and Technology (Boulder, Colorado)
ASSIGNEE(S) Boulder Environmental Sciences and Technology (Boulder, Colorado)
INVENTOR(S) Marian Klein (Boulder, Colorado)
ABSTRACT A system for passive microwave remote sensing using at least one microwave radiometer includes a fixed body portion, the fixed body portion being configured to attach to a mobile platform, and a mobile body portion, the mobile body portion being configured for rotatably coupling with the fixed body portion for rotation about a rotation axis. The mobile body portion is configured for supporting the at least one microwave radiometer therein such that the at least one microwave radiometer rotates about the rotation axis when the mobile body portion is rotated about the rotation axis such that a polarization axis of the at least one radiometer is aligned with an earth axis. The fixed body portion includes a motor mechanism for effecting rotation of the mobile body portion such that the at least one microwave radiometer provides a vertical scanning below and above the mobile platform.
FILED Wednesday, December 21, 2022
APPL NO 18/085710
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 11/006 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 22/00 (20130101)
G01N 22/04 (20130101) Original (OR) Class
G01N 33/2823 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 25/04 (20130101)
G01R 27/04 (20130101)
G01R 27/22 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852624 He et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Jin He (Miami, Florida);  Santosh Khatri (Miami, Florida);  Popular Pandey (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Jin He (Miami, Florida);  Santosh Khatri (Miami, Florida);  Popular Pandey (Miami, Florida)
ABSTRACT A system, apparatus, device and/or method for electrical label-free detection of single molecule via a glass or quartz nanopipette biosensor, one type of solid state nanopore biosensor based on resistive pulse measurements, are provided. The method of the subject invention effectively slows down the motion of biomolecules and concentrates them at the nanopipette tip. By driving biomolecules to come out of the nanopipette barrel and move in the fibrin hydrogel, unprecedented sensitivity using the typical size nanopipettes can be achieved. Small molecules such as doxorubicin, ATP, GTP, and short peptides can be easily detected with very high event rate, which greatly reduces the fabrication and measurement difficulties and open opportunities for various new applications for nanopipette biosensors.
FILED Tuesday, January 31, 2023
APPL NO 18/103746
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44791 (20130101)
G01N 33/48721 (20130101) Original (OR) Class

Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM]
G01Q 60/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852633 Wolf et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Georgetown University (Washington, District of Columbia)
ASSIGNEE(S) GEORGETOWN UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) Christian Wolf (Arlington, Virginia);  Fathima Yushra Thanzeel (Washington, District of Columbia)
ABSTRACT The present invention relates to compositions and methods for determining the absolute configuration of D/L-cysteine and/or the enantiomeric composition of cysteine and/or the concentration of total cysteine in a sample. Uses of the composition and method are also described.
FILED Saturday, November 26, 2022
APPL NO 17/994322
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 309/65 (20130101)
C07C 309/73 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/33 (20130101)
G01N 21/64 (20130101)
G01N 33/52 (20130101)
G01N 33/6815 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852781 Steinhardt et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Trustees of Princeton University (Princeton, New Jersey)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) Paul J Steinhardt (Princeton, New Jersey);  Marian Florescu (Surrey, United Kingdom);  Salvatore Torquato (Princeton, New Jersey)
ABSTRACT Waveguides and electromagnetic cavities fabricated in hyperuniform disordered materials with complete photonic bandgaps are provided. Devices comprising electromagnetic cavities fabricated in hyperuniform disordered materials with complete photonic bandgaps are provided. Devices comprising waveguides fabricated in hyperuniform disordered materials with complete photonic bandgaps are provided. The devices include electromagnetic splitters, filters, and sensors.
FILED Tuesday, July 13, 2021
APPL NO 17/374404
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 17/00 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/24 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/17 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/005 (20130101) Original (OR) Class
G02B 5/3025 (20130101)
G02B 6/125 (20130101)
G02B 6/1225 (20130101)
G02B 27/0012 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 33/16 (20130101)
H01L 33/0058 (20130101)
H01L 33/0095 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 29/49993 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852793 Weida et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) DAYLIGHT SOLUTIONS, INC. (San Diego, California)
ASSIGNEE(S) DAYLIGHT SOLUTIONS, INC. (San Diego, California)
INVENTOR(S) Miles James Weida (Poway, California);  Timothy Day (Poway, California)
ABSTRACT An imaging microscope (12) for generating an image of a sample (10) comprises a beam source (14) that emits a temporally coherent illumination beam (20), the illumination beam (20) including a plurality of rays that are directed at the sample (10); an image sensor (18) that converts an optical image into an array of electronic signals; and an imaging lens assembly (16) that receives rays from the beam source (14) that are transmitted through the sample (10) and forms an image on the image sensor (18). The imaging lens assembly (16) can further receive rays from the beam source (14) that are reflected off of the sample (10) and form a second image on the image sensor (18). The imaging lens assembly (16) receives the rays from the sample (10) and forms the image on the image sensor (18) without splitting and recombining the rays.
FILED Wednesday, January 19, 2022
APPL NO 17/579015
ART UNIT 2487 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/00 (20130101)
G02B 21/0056 (20130101) Original (OR) Class
G02B 21/0088 (20130101)
G02B 21/088 (20130101)
G02B 21/365 (20130101)

Pictorial Communication, e.g Television
H04N 5/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11853087 Ismagilov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Rustem F. Ismagilov (Chicago, Illinois);  Bo Zheng (Chicago, Illinois);  Cory John Gerdts (Chicago, Illinois)
ABSTRACT The present invention provides microfluidic technology enabling rapid and economical manipulation of reactions on the femtoliter to microliter scale.
FILED Monday, August 03, 2020
APPL NO 16/983270
ART UNIT 1796 — Optics
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 25/314 (20220101)
B01F 33/3021 (20220101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101)
B01J 2219/0059 (20130101)
B01J 2219/00522 (20130101)
B01J 2219/00585 (20130101)
B01J 2219/00599 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0293 (20130101)
B01L 3/502746 (20130101)
B01L 3/502784 (20130101)
B01L 2200/0673 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0838 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/0487 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/38 (20130101)
G01N 35/08 (20130101)
G01N 2035/1034 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 7/0694 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 137/0318 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11853244 Sankaralingam et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Karthikeyan Sankaralingam (Madison, Wisconsin);  Anthony Nowatzki (Madison, Wisconsin);  Vinay Gangadhar (Madison, Wisconsin)
ABSTRACT A reconfigurable hardware accelerator for computers combines a high-speed dataflow processor, having programmable functional units rapidly reconfigured in a network of programmable switches, with a stream processor that may autonomously access memory in predefined access patterns after receiving simple stream instructions. The result is a compact, high-speed processor that may exploit parallelism associated with many application-specific programs susceptible to acceleration.
FILED Thursday, January 26, 2017
APPL NO 15/416670
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3455 (20130101)
G06F 9/3834 (20130101)
G06F 9/3877 (20130101)
G06F 9/4494 (20180201)
G06F 9/30087 (20130101)
G06F 13/1689 (20130101)
G06F 13/4022 (20130101) Original (OR) Class
G06F 15/76 (20130101)
G06F 15/825 (20130101)
G06F 15/7889 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11854281 Kaufman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S) Arie Kaufman (Plainview, New York);  Saeed Boorboor (Lake Grove, New York)
ABSTRACT An exemplary system, method, and computer-accessible medium for generating an image(s) of an anatomical structure(s) in a biological sample(s) can include receiving first wide field microscopy imaging information for the biological sample, generating second imaging information by applying a gradient-based distance transform to the first imaging information, and generating the image(s) based on the second imaging information. The second imaging information can be generated by applying an anisotropic diffusion procedure to the first imaging information. The second imaging information can be generated by applying a curvilinear filter and a Hessian-based enhancement filter after the application of the gradient-based distance transform. The second information can be generated by applying (i) a tube enhancement procedure or (ii) a plate enhancement procedure after the application of the gradient-based distance transform.
FILED Monday, August 17, 2020
APPL NO 16/994885
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/10056 (20130101)
G06T 2207/20021 (20130101)
G06T 2207/30016 (20130101)
G06T 2207/30024 (20130101)

Image or Video Recognition or Understanding
G06V 20/695 (20220101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11854379 Guerin et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
National Robotics Initiative (NRI)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland)
INVENTOR(S) Kelleher Guerin (Baltimore, Maryland);  Gregory Hager (Baltimore, Maryland)
ABSTRACT Provided is a method, device, and computer-readable medium for controlling a robot graphic user interface (“RGUI”) on a mobile device. The method can include determining a distance, a position, or both of the mobile device with respect to a first robot; and causing, by a processor, a first RGUI to be displayed on a display of the mobile device based on the determining.
FILED Thursday, August 19, 2021
APPL NO 17/406589
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/409 (20130101)
G05B 2219/39384 (20130101)
G05B 2219/40382 (20130101)

Transmission Systems for Measured Values, Control or Similar Signals
G08C 17/02 (20130101) Original (OR) Class
G08C 2201/20 (20130101)
G08C 2201/30 (20130101)
G08C 2201/70 (20130101)
G08C 2201/91 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11855348 Kamali et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Seyedeh Mahsa Kamali (Arcadia, California);  Ehsan Arbabi (Arcadia, California);  Andrei Faraon (La Canada Flintridge, California)
ABSTRACT Cascaded metasurfaces can control the phase, amplitude and polarization of an electromagnetic beam, shaping it in three dimensional configuration not achievable with other methods. Each cascaded metasurface has dielectric or metallic scatterers arranged in a period array. The shape of the scatterers determines the three dimensional configuration of the output beam and is determined with iterative calculations through computational simulations.
FILED Friday, June 17, 2022
APPL NO 17/843302
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 5/3083 (20130101)
G02B 27/0012 (20130101)
G02B 27/44 (20130101)
G02B 27/0944 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/00 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/70408 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/422 (20130101)
H01Q 1/425 (20130101)
H01Q 15/242 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11856013 Bowman et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) The George Washington University (Washington, District of Columbia)
INVENTOR(S) Benjamin Bowman (Kensington, Maryland);  Craig Laprade (Fairfax, Virginia);  H. Howie Huang (McLean, Virginia)
ABSTRACT A system includes a log receiving module, an authentication graph module, a sampling module, an embedding module, a training module, a link prediction module, and an anomaly detection module. The log receiving module is configured to receive a first plurality of network-level authentication logs. The authentication graph module is configured to generate an authentication graph. The sampling module is configured to generate a plurality of sequences. The embedding module is configured to tune a plurality of node embeddings according to the plurality of sequences. The training module is configured to train a link predictor according to the plurality of node embeddings and ground-truth edge information from the authentication graph. The link prediction module is configured to apply the link predictor to performs a link prediction. The anomaly detection module is configured to perform anomaly detection according to the link prediction.
FILED Monday, June 29, 2020
APPL NO 16/915183
ART UNIT 2469 — Multiplex and VoIP
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 20/00 (20190101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/0876 (20130101)
H04L 63/1425 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11850639 Campanella et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Loci Controls, Inc. (Wareham, Massachusetts)
ASSIGNEE(S) Loci Controls, Inc. (Wareham, Massachusetts)
INVENTOR(S) Andrew Campanella (Somerville, Massachusetts);  Joseph G. Michels (New York, New York);  Peter Quigley (Duxbury, Massachusetts);  Ian Martin (Sharon, Massachusetts)
ABSTRACT A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas.
FILED Thursday, June 01, 2023
APPL NO 18/327694
ART UNIT 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Disposal of Solid Waste
B09B 1/006 (20130101) Original (OR) Class

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852493 Schaefer
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Philip Raymond Schaefer (Weaverville, North Carolina)
ASSIGNEE(S) Vortant Technologies, LLC (Weaverville, North Carolina)
INVENTOR(S) Philip Raymond Schaefer (Weaverville, North Carolina)
ABSTRACT A system provides feedback to a user to guide the user to point a part of the body at a target of interest. An angle sensor senses the angle in which the part of the user's body is pointing, such as the head or the hand. The system computes the angle to a target and compares to the angle in which the part of the user's body is pointing and the feedback indicates to the user how to point more closely to the direction of the target. Additional sensors allow the system to update the angle to the target as the position of the user changes. A walking sensor is disclosed to accurately measure the position of the user.
FILED Tuesday, June 15, 2021
APPL NO 17/348256
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3415 (20130101) Original (OR) Class
G01C 21/3476 (20130101)
G01C 21/3629 (20130101)

Electric Digital Data Processing
G06F 3/011 (20130101)
G06F 3/012 (20130101)
G06F 3/013 (20130101)
G06F 3/016 (20130101)
G06F 3/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852793 Weida et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) DAYLIGHT SOLUTIONS, INC. (San Diego, California)
ASSIGNEE(S) DAYLIGHT SOLUTIONS, INC. (San Diego, California)
INVENTOR(S) Miles James Weida (Poway, California);  Timothy Day (Poway, California)
ABSTRACT An imaging microscope (12) for generating an image of a sample (10) comprises a beam source (14) that emits a temporally coherent illumination beam (20), the illumination beam (20) including a plurality of rays that are directed at the sample (10); an image sensor (18) that converts an optical image into an array of electronic signals; and an imaging lens assembly (16) that receives rays from the beam source (14) that are transmitted through the sample (10) and forms an image on the image sensor (18). The imaging lens assembly (16) can further receive rays from the beam source (14) that are reflected off of the sample (10) and form a second image on the image sensor (18). The imaging lens assembly (16) receives the rays from the sample (10) and forms the image on the image sensor (18) without splitting and recombining the rays.
FILED Wednesday, January 19, 2022
APPL NO 17/579015
ART UNIT 2487 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/00 (20130101)
G02B 21/0056 (20130101) Original (OR) Class
G02B 21/0088 (20130101)
G02B 21/088 (20130101)
G02B 21/365 (20130101)

Pictorial Communication, e.g Television
H04N 5/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11849688 Klessig et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Boyce Thompson Institute for Plant Research, Inc. (Ithaca, New York)
ASSIGNEE(S) Boyce Thompson Institute for Plant Research, Inc. (Ithaca, New York)
INVENTOR(S) Daniel F. Klessig (Dryden, New York);  Frank Schroeder (Itaca, New York);  Patricia Manosalva (Ithaca, New York)
ABSTRACT Compositions and methods for enhancing disease resistance in plants are disclosed.
FILED Monday, May 03, 2021
APPL NO 17/306166
ART UNIT 1663 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 3/04 (20130101) Original (OR) Class

Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 43/16 (20130101)
A01N 43/38 (20130101)
A01N 63/10 (20200101)
A01N 63/12 (20200101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/8281 (20130101)
C12N 15/8282 (20130101)
C12N 15/8283 (20130101)
C12N 15/8285 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11851644 Nelson et al.
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island)
ASSIGNEE(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island)
INVENTOR(S) David R. Nelson (Wakefield, Rhode Island);  Jason LaPorte (Riverside, Rhode Island);  David C Rowley (Wakefield, Rhode Island);  Marta Gomez-Chiarri (Kingston, Rhode Island)
ABSTRACT The invention provides a method and related compositions for preparing an effective probiotic bacteria formulation that can be stored, transported and used for protecting a variety of marine organisms against infection by potential pathogens.
FILED Monday, May 04, 2020
APPL NO 16/866265
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/741 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101) Original (OR) Class
C12N 2500/05 (20130101)
C12N 2500/32 (20130101)
C12N 2500/74 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11851644 Nelson et al.
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island)
ASSIGNEE(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island)
INVENTOR(S) David R. Nelson (Wakefield, Rhode Island);  Jason LaPorte (Riverside, Rhode Island);  David C Rowley (Wakefield, Rhode Island);  Marta Gomez-Chiarri (Kingston, Rhode Island)
ABSTRACT The invention provides a method and related compositions for preparing an effective probiotic bacteria formulation that can be stored, transported and used for protecting a variety of marine organisms against infection by potential pathogens.
FILED Monday, May 04, 2020
APPL NO 16/866265
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/741 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101) Original (OR) Class
C12N 2500/05 (20130101)
C12N 2500/32 (20130101)
C12N 2500/74 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852596 Klein
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Boulder Environmental Sciences and Technology (Boulder, Colorado)
ASSIGNEE(S) Boulder Environmental Sciences and Technology (Boulder, Colorado)
INVENTOR(S) Marian Klein (Boulder, Colorado)
ABSTRACT A system for passive microwave remote sensing using at least one microwave radiometer includes a fixed body portion, the fixed body portion being configured to attach to a mobile platform, and a mobile body portion, the mobile body portion being configured for rotatably coupling with the fixed body portion for rotation about a rotation axis. The mobile body portion is configured for supporting the at least one microwave radiometer therein such that the at least one microwave radiometer rotates about the rotation axis when the mobile body portion is rotated about the rotation axis such that a polarization axis of the at least one radiometer is aligned with an earth axis. The fixed body portion includes a motor mechanism for effecting rotation of the mobile body portion such that the at least one microwave radiometer provides a vertical scanning below and above the mobile platform.
FILED Wednesday, December 21, 2022
APPL NO 18/085710
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 11/006 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 22/00 (20130101)
G01N 22/04 (20130101) Original (OR) Class
G01N 33/2823 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 25/04 (20130101)
G01R 27/04 (20130101)
G01R 27/22 (20130101)

Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 3/17 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11852080 O'Connor et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) GENERAL ELECTRIC COMPANY (Schenectady, New York)
INVENTOR(S) Ethan Patrick O'Connor (Hamilton, Ohio);  Gert J. van der Merwe (Lebanon, Ohio);  Barry L. Allmon (Matthews, North Carolina)
ABSTRACT A gearbox assembly includes a first gear coupled to a first shaft, a second gear coupled to a second shaft, and a plurality of planet gears that mesh with the first gear and the second gear. The first shaft includes a first shaft stiff portion and a first shaft flexible portion that includes a greater flexibility than a flexibility of the first shaft stiff portion such that the first gear moves in a radial direction. The second shaft includes a second shaft stiff portion and a second shaft flexible portion that includes a greater flexibility than a flexibility of the second shaft stiff portion such that the second gear moves in the radial direction. The first gear and the second gear move to distribute loads substantially equally on the plurality of planet gears.
FILED Friday, August 05, 2022
APPL NO 17/817852
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/06 (20130101)
F02C 7/36 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/323 (20130101)
F05D 2260/40311 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11852864 Stephen et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Mark Stephen (Catonsville, Maryland);  Renan Moreira (Santa Barbara, California);  Fabrizio Gambini (Santa Barbara, California)
ABSTRACT An arrayed waveguide for a photonic integrated circuit has a single optical path with serially connected delay lines. Different delayed optical paths or channels are periodically split off from the serially connected optical delay path. This has the net result of requiring much less space on-chip for comparable optical path differences with high spectral resolution.
FILED Tuesday, March 01, 2022
APPL NO 17/684016
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/122 (20130101)
G02B 6/12011 (20130101) Original (OR) Class
G02B 2006/1215 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11850878 Zlotnick et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Joel Zlotnick (Arlington, Virginia);  Jordan Brough (Leesburg, Virginia);  Troy Eberhardt (Centreville, Virginia);  Tyra McConnell (Knoxville, Maryland);  Elizabeth Gil (Bristow, Virginia);  Traci Moran (Rockville, Maryland)
ABSTRACT A substrate is printed with front side and back side markings. The front side when viewed with reflected light includes: a first marking printed with a first gradient of two colors; a second marking printed with a second gradient of two colors; a first symbol printed with a third gradient of two colors; a second symbol printed with a fourth gradient of two colors; a third symbol printed with a fifth gradient of two colors; and a fourth symbol printed with a sixth gradient of two colors. The back side when viewed with reflected light includes: a third marking printed with the fourth gradient; a fourth marking printed with the third gradient; a fifth symbol printed with the second gradient; a sixth symbol printed with the first gradient; a seventh symbol printed with the sixth gradient; and an eighth symbol printed with the fifth gradient.
FILED Friday, October 07, 2022
APPL NO 17/962053
ART UNIT 3637 — Static Structures, Supports and Furniture
CURRENT CPC
Printing Machines or Presses
B41F 1/16 (20130101)
B41F 7/025 (20130101)
B41F 31/008 (20130101)

Printing, Duplicating, Marking, or Copying Processes; Colour Printing,
B41M 1/14 (20130101)
B41M 3/14 (20130101)
B41M 3/148 (20130101)
B41M 2205/34 (20130101)

Indexing Scheme Relating to Printing, Lining Machines, Typewriters, and to Stamps
B41P 2227/10 (20130101)

Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus
B42D 25/29 (20141001) Original (OR) Class
B42D 25/333 (20141001)
B42D 25/342 (20141001)
B42D 25/378 (20141001)
B42D 25/405 (20141001)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Justice (DOJ) 

US 11854245 Xu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Department of Justice (DOJ)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
INVENTOR(S) Felix Juefei Xu (Pittsburgh, Pennsylvania);  Marios Savvides (Pittsburgh, Pennsylvania)
ABSTRACT The invention specifies a method of improving a subsequent iterations of a generative network by adding a ranking loss to the total loss for the network, the ranking loss representing the marginalized difference between a discriminator score for a generated image in one iteration of the generative network and the discriminator score for a real image from a subsequent iteration of the generative network.
FILED Monday, April 29, 2019
APPL NO 16/976417
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 17/11 (20130101)
G06F 18/22 (20230101)
G06F 18/2113 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/045 (20230101)
G06N 3/047 (20230101)
G06N 3/084 (20130101)
G06N 3/088 (20130101)
G06N 3/0455 (20230101)
G06N 3/0475 (20230101)
G06N 20/20 (20190101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101) Original (OR) Class
G06V 10/454 (20220101)
G06V 10/761 (20220101)
G06V 40/168 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11850259 Ganio
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Carl Ganio (Wilmington, North Carolina)
ABSTRACT This disclosure relates to topical lithium agents including inhalable lithium agents for treating a viral infection characterized by a cytokine storm in the respiratory tract of a subject such as a human. Topical lithium formulations can be used to mitigate such viral infections, including coronavirus infections.
FILED Tuesday, October 05, 2021
APPL NO 17/494230
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0073 (20130101)
A61K 33/14 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 11854366 Thoma et al.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S) United States Environmental Protection Agency (Washington, District of Columbia);  Flint Hills Resources Corpus Christi, LLC (Corpus Christi, Texas);  Molex, LLC (Lisle, Illinois)
ASSIGNEE(S)
INVENTOR(S) Eben Daniel Thoma (Cary, North Carolina);  Deborah Lynn Preschler (Corpus Christi, Texas);  Roger John Hilarides (Wichita, Kansas);  Debra Jean Cartwright (Sandia, Texas);  Michael Stephen Clausewitz (Corpus Christi, Texas);  Barry William Kelley (Edina, Minnesota);  David Randall Massner (Corpus Christi, Texas);  Wenfeng Peng (North Aurora, Illinois);  Marko Frank Spiegel (Lafox, Illinois)
ABSTRACT The present disclosure provides a leak monitoring system and associated method which is being configured to detect plumes of volatile organic compounds (VOC) as an alternative solution to the EPA Method 21, which measures VOC concentrations at the surface of each component. The leak monitoring system is a multi-layered system that includes monitoring performed by sensors that are fixed in place and sensors that are mobile. Each monitoring method is a layer and it complements and augments other layers. All the sensors wirelessly communicate with a central control through a gateway. The control unit further includes a software platform, which analyzes the data provided by the sensors in combination with other informetrics such as meteorological conditions and plant info to both identify the presence of a gas leak and to pinpoint a general location of the gas leak. When a significant gas leak is identified, the control unit sends an alert to plant managers via text or email, in addition to activating visual and/or audible alarms.
FILED Thursday, February 13, 2020
APPL NO 16/790712
ART UNIT 2685 — Selective Communication
CURRENT CPC
Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 3/04 (20130101)

Meteorology
G01W 1/02 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 21/12 (20130101) Original (OR) Class

Selecting
H04Q 9/00 (20130101)
H04Q 2209/40 (20130101)
H04Q 2209/823 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11850233 Zamadar
FUNDED BY
Non-Profit Organization (NPO)
Robert A. Welch Foundation
U.S. State Government
State of Texas
Texas Stephen F Austin State University Research Enhancement Program (SFASUREP)
APPLICANT(S) Matibur Rahaman Zamadar (Nacogdoches, Texas)
ASSIGNEE(S)
INVENTOR(S) Matibur Rahaman Zamadar (Nacogdoches, Texas)
ABSTRACT Next generation therapeutics for treatment of microorganisms (especially bacterium, fungus or certain virus) and cancer and for fluorescence diagnosis are provided. Association complex(es) effective as bactericides are formed in situ by loose interactions of molecular entities. Adjustable variable associations reduce chance bacteria develops adaptive resistance versus a single bactericide structure or method. Multifunctional variations simultaneously or sequentially attack target cells and adjust level of reactive oxygen species produced such as singlet oxygen. Claimed systems are effective bactericides in aerobic and anaerobic conditions and in absence of or presence of visible light. In presence of visible light in aerobic conditions, such are cancer treatments. Preferred are water soluble, nontoxic association complex(es). Variations can be formed by varying porphyrins and interacted metal ions, for illustration, tetrakis Ar substituted porphyrin without bound metal at core but combined with divalent metals of spatial and/or charge density characteristics similar to Zn(II) such as Co(II), Fe(II), and Mn(II).
FILED Monday, October 28, 2019
APPL NO 16/666323
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 43/40 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 8/19 (20130101)
A61K 8/4926 (20130101)
A61K 31/409 (20130101) Original (OR) Class
A61K 33/26 (20130101)
A61K 33/30 (20130101)
A61K 33/32 (20130101)
A61K 41/0071 (20130101)

Specific Use of Cosmetics or Similar Toilet Preparations
A61Q 17/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 11853846 Chalamalasetti et al.
FUNDED BY
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Spring, Texas)
INVENTOR(S) Sai Rahul Chalamalasetti (Milpitas, California);  Paolo Faraboschi (Milpitas, California);  Martin Foltin (Fort Collins, Colorado);  Catherine Graves (Milpitas, California);  Dejan S. Milojicic (Milpitas, California);  John Paul Strachan (Milpitas, California);  Sergey Serebryakov (Milpitas, California)
ABSTRACT A crossbar array includes a number of memory elements. An analog-to-digital converter (ADC) is electronically coupled to the vector output register. A digital-to-analog converter (DAC) is electronically coupled to the vector input register. A processor is electronically coupled to the ADC and to the DAC. The processor may be configured to determine whether division of input vector data by output vector data from the crossbar array is within a threshold value, and if not within the threshold value, determine changed data values as between the output vector data and the input vector data, and write the changed data values to the memory elements of the crossbar array.
FILED Monday, April 30, 2018
APPL NO 17/044633
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101) Original (OR) Class

Static Stores
G11C 13/0069 (20130101)
G11C 2213/77 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 11850233 Zamadar
FUNDED BY
Non-Profit Organization (NPO)
Robert A. Welch Foundation
U.S. State Government
State of Texas
Texas Stephen F Austin State University Research Enhancement Program (SFASUREP)
APPLICANT(S) Matibur Rahaman Zamadar (Nacogdoches, Texas)
ASSIGNEE(S)
INVENTOR(S) Matibur Rahaman Zamadar (Nacogdoches, Texas)
ABSTRACT Next generation therapeutics for treatment of microorganisms (especially bacterium, fungus or certain virus) and cancer and for fluorescence diagnosis are provided. Association complex(es) effective as bactericides are formed in situ by loose interactions of molecular entities. Adjustable variable associations reduce chance bacteria develops adaptive resistance versus a single bactericide structure or method. Multifunctional variations simultaneously or sequentially attack target cells and adjust level of reactive oxygen species produced such as singlet oxygen. Claimed systems are effective bactericides in aerobic and anaerobic conditions and in absence of or presence of visible light. In presence of visible light in aerobic conditions, such are cancer treatments. Preferred are water soluble, nontoxic association complex(es). Variations can be formed by varying porphyrins and interacted metal ions, for illustration, tetrakis Ar substituted porphyrin without bound metal at core but combined with divalent metals of spatial and/or charge density characteristics similar to Zn(II) such as Co(II), Fe(II), and Mn(II).
FILED Monday, October 28, 2019
APPL NO 16/666323
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 43/40 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 8/19 (20130101)
A61K 8/4926 (20130101)
A61K 31/409 (20130101) Original (OR) Class
A61K 33/26 (20130101)
A61K 33/30 (20130101)
A61K 33/32 (20130101)
A61K 41/0071 (20130101)

Specific Use of Cosmetics or Similar Toilet Preparations
A61Q 17/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11852270 Swernofsky et al.
FUNDED BY
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) David E. Swernofsky (Richardson, Texas);  Robert Larson (Dallas, Texas)
ABSTRACT A fluid system and a blind-mate fluid fitting can be operable to allow for mating fluid system components even in the presence of angular, radial, and/or axial port misalignment. The blind-mate fluid fitting includes a shoulder and fitting portion extending from one side of the shoulder. The fitting portion defines a central fitting axis and is operable to inserted into a fluid port of a component. The fluid port defines a central port axis. The fitting portion includes a sealing portion that is operable to seal against the fluid port when the central fitting axis is positioned at a zero angle and at least one of a plurality of different non-zero angles relative to the central port axis.
FILED Friday, July 30, 2021
APPL NO 17/390863
ART UNIT 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 17/00 (20130101)
F16L 37/52 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, December 26, 2023.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20231226.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital