FedInvent™ Patent Applications
Application Details for Thursday, January 11, 2024
This page was updated on Tuesday, June 18, 2024 at 02:11 PM GMT
Department of Health and Human Services (HHS)
| US 20240008855 | Egorov |
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| FUNDED BY |
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| APPLICANT(S) | Vladimir Egorov (Princeton, New Jersey) |
| ASSIGNEE(S) | Advanced Tactile Imaging Inc. (Ewing Township, New Jersey) |
| INVENTOR(S) | Vladimir Egorov (Princeton, New Jersey) |
| ABSTRACT | A cervical probe, equipped with both a tactile sensor array and an ultrasound transducer array, is engineered for the simultaneous acquisition of stress and ultrasound strain data from cervical sectors, as well as for the measurement of cervical length. The collected stress and strain data from various cervical sectors are transmitted to a data processor. This processor calculates cervical elasticity using a strain-to-stress ratio. Subsequently, the arithmetic mean of the stress-to-strain ratios is compared with a predetermined cutoff value, and the measured cervical length is evaluated against another predetermined value, to predict preterm birth during gestational weeks 24-28. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/370439 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/12 (20130101) A61B 8/485 (20130101) A61B 8/0866 (20130101) A61B 8/5223 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009032 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | David Huang (Portland, Oregon); Gangjun Liu (Portland, Oregon); Jianlong Yang (Portland, Oregon); Stephen Pflugfelder (Portland, Oregon) |
| ABSTRACT | Disclosed is a handheld laser probe for laser thermal conjunctivoplasty, the handheld laser comprising: a forceps; and a line focused laser light source coupled to the forceps, wherein the forceps are configured to grasp a conjunctival fold and hold the fold in a light beam of the line focused laser, and wherein the line focused laser beam is configured to uniformly heat the conjunctival fold held in the forceps. Disclosed are systems for laser thermal conjunctivoplasty including the handheld laser. Disclosed are methods of conjunctivoplasty using the handheld laser probe. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/475029 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/285 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009040 | McCarthy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Tricol Biomedical, Inc. (Portland, Oregon); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Simon J. McCarthy (Portland, Oregon); Mattie R. Jones (Portland, Oregon); Hua Xie (Portland, Oregon) |
| ABSTRACT | The present disclosure relates to a gastrointestinal delivery device of a chitosan dressing, where the delivery device is capable of stop bleeding, in particular in connection with TURP procedures. The delivery device may be used in all gastrointestinal bleeding applications and can be used with a biocompatible, foldable, thin profile, chitosan dressing. Various aspects of the device and its uses are provided herein. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/160953 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/36 (20130101) A61F 13/266 (20130101) Original (OR) Class A61F 13/2071 (20130101) A61F 2013/2014 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/28 (20130101) A61L 15/44 (20130101) A61L 2400/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009170 | EL-DEIRY et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wafik S. EL-DEIRY (Barrington, Rhode Island); Kelsey HUNTINGTON (Providence, Rhode Island); Benedito A. CARNEIRO (East Greenwich, Rhode Island) |
| ABSTRACT | The invention provides small-molecule inhibition of GSK-3 to increase efficacy of ICB and improve response in patients with microsatellite stable colorectal cancer, and possibly other tumor types. These results demonstrate 9-ING-41 in combination with αPD-1/PD-L1 therapy. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 18/251868 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) Original (OR) Class A61K 33/14 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009174 | CHANDRA et al. |
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| FUNDED BY |
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| APPLICANT(S) | Health Research, Inc. (Buffalo, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dhyan CHANDRA (Buffalo, New York); Rahul KUMAR (Buffalo, New York); Neelu YADAV (Buffalo, New York) |
| ABSTRACT | The present disclosure provides methods for treating an individual in need of a composition having a compound having the following structure: Formula (I) The methods may be used to disrupt mitochondrial unfolded protein response. In various examples, a compound of the composition binds to heat shock protein 60 (HSP60) and inhibits the interaction of HSP60 to ClpP, thus interrupting the mitochondrial unfolded protein response. For example, the composition may be used as a therapeutic approach for treating advanced prostate cancers that are no longer sensitive to AR targeted therapies. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 18/252024 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009179 | Rehman et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
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| INVENTOR(S) | Tayyab Rehman (Iowa City, Iowa); Michael J. Welsh (Iowa City, Iowa) |
| ABSTRACT | Disclosed are methods for the treatment of cystic fibrosis, methods of increasing airway surface liquid pH, methods of enhancing respiratory defense, and methods of testing a compound of interest for use as a treatment for cystic fibrosis. |
| FILED | Wednesday, July 05, 2023 |
| APPL NO | 18/347192 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4545 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) G01N 33/5044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009183 | Ekins et al. |
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| FUNDED BY |
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| APPLICANT(S) | Collaborations Pharmaceuticals, Inc. (Fuquay Varina, North Carolina) |
| ASSIGNEE(S) | Collaborations Pharmaceuticals, Inc. (Fuquay Varina, North Carolina) |
| INVENTOR(S) | Sean Ekins (Fuquay Varina, North Carolina); Thomas R. Lane (Durham, North Carolina); Ana C. Puhl (Fuquay Varina, North Carolina) |
| ABSTRACT | Methods of treating or preventing diseases caused by viral infections via the administration of pyronaridine, quinacrine, and/or tilorone are described. The viral infections can be caused by viruses such as Marburg virus (MARV), Chikungunya virus (CHIKV), norovirus, Middle East Respiratory Syndrome coronavirus (MERS-CoV), and Nipah virus. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/220034 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/138 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009222 | Imai et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Shin-ichiro Imai (St. Louis, Missouri); Rajendra Apte (Clayton, Missouri) |
| ABSTRACT | Disclosed are methods and compositions related to methods of treating, ameliorating, mitigating, slowing, arresting, preventing or reversing various diseases and conditions, including age-related obesity, age-related increases in blood lipid levels, age-related decreases in insulin sensitivity, age-related decreases in memory function, and age-related changes in eye function such as macular degeneration. The methods comprise administering nicotinamide mononucleotide (NMN) to a subject. In some embodiments, the administration can be oral administration. Also disclosed are pharmaceutical compositions comprising NMN. |
| FILED | Thursday, September 21, 2023 |
| APPL NO | 18/471764 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0048 (20130101) A61K 9/0053 (20130101) A61K 31/455 (20130101) A61K 31/706 (20130101) Original (OR) Class A61K 31/7064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009231 | MCCORMACK et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | FRANCIS X MCCORMACK (Terrace Park, Ohio); YUSUKE TANAKA (Sapporo, Japan) |
| ABSTRACT | A method to treat pneumothorax or malignant pleural effusion by pleurodesis in a mammalian subject is disclosed. The method involves administering particles to the lungs, the pleural space or both. The particles comprise a crystalline material that is non-toxic and is cleared over time by biodegradation. In some embodiments, the biodegraded crystalline material is readily cleared by the kidneys. In one embodiment, the crystalline material is essentially cleared from the lungs a few months after treatment. |
| FILED | Monday, September 27, 2021 |
| APPL NO | 18/027932 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 9/0019 (20130101) A61K 9/1611 (20130101) A61K 33/42 (20130101) Original (OR) Class A61K 47/6923 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009236 | Childs et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Richard W. Childs (Bethesda, Maryland); Emily R. Levy (Bethesda, Maryland); Joseph Clara (Bethesda, Maryland) |
| ABSTRACT | Modified NK cells with reduced expression of CCR5 are provided. Methods of treating a subject with cancer with the modified NK cells are also provided. In some examples, the modified NK cells also have reduced expression of one or more of CCR1, CXCR6, and CD38, increased expression of one or more of CXCR4, CCR7, and CXCR3, and/or express a chimeric antigen receptor. |
| FILED | Wednesday, November 03, 2021 |
| APPL NO | 18/035240 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009243 | PEREZ et al. |
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| FUNDED BY |
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| APPLICANT(S) | Kite Pharma, Inc. (Santa Monica, California); The United States of America, as represented by the Secretary, Department of Health and Human Ser. (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arianne PEREZ (Santa Monica, California); Marianna SABATINO (Santa Monica, California); Steven A. ROSENBERG (Bethesda, Maryland); Nicholas P. RESTIFO (Bethesda, Maryland) |
| ABSTRACT | Provided herein are methods for delaying or inhibiting T cell maturation or differentiation in vitro for a T cell therapy, comprising contacting one or more T cells from a subject in need of a T cell therapy with an AKT inhibitor and at least one of exogenous Interleukin-7 (IL-7) and exogenous Interleukin-15 (IL-15), wherein the resulting T cells exhibit delayed maturation or differentiation. In some embodiments, the method further comprises administering the one or more T cells to a subject in need of a T cell therapy. |
| FILED | Monday, June 26, 2023 |
| APPL NO | 18/341692 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2500/30 (20130101) C12N 2501/2307 (20130101) C12N 2501/2315 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009247 | Cherqui et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
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| INVENTOR(S) | Stephanie Cherqui (La Jolla, California); Eric Adler (La Jolla, California); Sylvia Evans (La Jolla, California) |
| ABSTRACT | Provided herein are methods for treating a lysosomal transmembrane protein disease or disorder through ex vivo introduction of a nucleic acid molecule into hematopoietic stem and progenitor cells (HSPCs) followed by transplantation of the HSPCs into a subject in need of treatment. Also provided are vectors containing the nucleic acid molecule. |
| FILED | Tuesday, June 27, 2023 |
| APPL NO | 18/342642 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) A61K 35/28 (20130101) Original (OR) Class A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) Peptides C07K 14/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009256 | Feng et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Wenke Feng (Prospect, Kentucky); Craig J. McClain (Louisville, Kentucky) |
| ABSTRACT | Provided are probiotic bacterium-derived extracellular micro- and/or nanoparticles. Also provided are methods for purifying the probiotic bacterium-derived extracellular micro- and/or nanoparticles and methods for using the disclosed probiotic bacterium-derived extracellular micro- and/or nanoparticles to treat liver diseases and/or disorders including but not limited to acute liver failure (ALT), alcoholic liver disease (ALD), non-alcoholic liver disease, alcoholic hepatitis (AH), liver steatosis, liver fibrosis and/or cholestatic liver disease; increasing intestinal aryl hydrocarbon receptor (AhR) activity, Nrf2 signaling, IL-22 expression, regenerating islet-derived 3β (Reg3P) expression, and/or regenerating islet-derived 3γ (Reg3y) expression; maintaining gut microbiota homeostasis; preventing or reducing bacterial intestinal transcytosis; increasing intestinal tight junctions; decreasing circulating LPS concentration; protecting intestinal barrier integrity against oxidative stress; regulating intestinal Nrf2 signaling; increasing intestinal EGF secretion, hepatic macrophage HB-EGF cleavage and activation; and hepatic EGER activation. |
| FILED | Thursday, February 04, 2021 |
| APPL NO | 17/797219 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/404 (20130101) A61K 31/405 (20130101) A61K 35/747 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/04 (20180101) A61P 1/16 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009257 | Vile et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard G. Vile (Rochester, Minnesota); Laura Evgin (Vancouver, Canada); Amanda L. Huff (Rochester, Minnesota); Christopher B. Driscoll (Waltham, Massachusetts); Timothy J. Kottke (Oronoco, Minnesota); Jason M. Tonne (Rochester, Minnesota); Jill M. Thompson (Kasson, Minnesota); Brady N. Zell (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials for treating cancer. For example, methods and materials for using oncolytic viruses (e.g., replication-competent vesicular stomatitis viruses) to treat cancer are provided. Replication-competent oncolytic viruses (e.g., replication-competent oncolytic vesicular stomatitis viruses), nucleic acid molecules encoding a replication-competent oncolytic virus (e.g., replication-competent oncolytic vesicular stomatitis virus), methods for making replication-competent oncolytic viruses (e.g., replication-competent oncolytic vesicular stomatitis viruses), methods for using replication-competent oncolytic viruses (e.g., replication-competent oncolytic vesicular stomatitis viruses) to treat cancer, cancer neoantigens, nucleic acids encoding a cancer neoantigen, and methods for stimulating immune cells (e.g., cytotoxic T lymphocytes) to kill cancer cells also are provided. |
| FILED | Thursday, September 23, 2021 |
| APPL NO | 18/027768 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/766 (20130101) Original (OR) Class A61K 38/08 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2760/20222 (20130101) C12N 2760/20232 (20130101) C12N 2760/20243 (20130101) C12N 2760/20271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009272 | Herman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of The University of Arizona (Tucson, Arizona) |
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| INVENTOR(S) | Eliot M. Herman (Tucson, Arizona); Monica Schmidt (Tucson, Arizona); Marvin J. Slepian (Tucson, Arizona) |
| ABSTRACT | Compositions and materials comprising transgenic soybeans expressing a codon-optimized gene encoding of the hEGF protein. Using these methods, the production of hEGF is sufficient and cost-effective, thus providing a more economical way to produce medical materials comprising said protein. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/174158 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 36/48 (20130101) A61K 38/28 (20130101) A61K 38/39 (20130101) A61K 38/1709 (20130101) A61K 38/1808 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009288 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California) |
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| INVENTOR(S) | Xiuli Wang (Temple City, California); Stephen J. Forman (Duarte, California) |
| ABSTRACT | Chimeric antigen receptors for use in treating malignant melanoma and other cancers expressing CS1 are described. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/349678 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/35 (20130101) C07K 14/71 (20130101) C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 16/2803 (20130101) C07K 16/2896 (20130101) C07K 2317/53 (20130101) C07K 2317/526 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/033 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0637 (20130101) C12N 5/0638 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009290 | Tolia et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Niraj H. Tolia (Bethesda, Maryland); Rui Ma (Bethesda, Maryland); Patrick E. Duffy (Washington, District of Columbia); Jonathan P. Renn (Falls Church, Virginia) |
| ABSTRACT | The disclosure provides immunogen polypeptides comprising fragments of VAR2CSA protein expressed by P. falciparum. Aspects of the disclosed immunogen polypeptides comprise all or portions of the CSA binding regions of VAR2CSA as identified by a structural study of VAR2CSA conducted by the inventors. Also provided are compositions comprising such immunogen polypeptides, and methods of using the immunogen polypeptides for vaccination and treatment of disease. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 18/037837 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 2039/55566 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Peptides C07K 14/445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009292 | Singh et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alok Singh (Baltimore, Maryland); Peter Um (Baltimore, Maryland); Keira Cohen (Baltimore, Maryland); William Bishai (Baltimore, Maryland); Rullin Wang (Baltimore, Maryland); Srinivasan Yegnasubramanian (Baltimore, Maryland); Trinity J. Bivalacqua (Baltimore, Maryland) |
| ABSTRACT | The present disclosure relates to a BCG based therapeutic agent using a BCG strain that overexpresses the STING agonist, c-di-AMP. This BCG strain, called BCG-disA-OE, enhances the elevated trained immunity of macrophages and promotes early anti-viral Type I interferon responses in a subject, providing protection against viral infections such as primary respiratory infections and SARS-CoV-2 infection. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 18/029599 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 39/04 (20130101) Original (OR) Class A61K 2039/58 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009299 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Feixiong Cheng (Cleveland, Ohio); William Martin (Cleveland, Ohio) |
| ABSTRACT | The present invention provides compositions comprising polypeptides comprising a plurality of epitopes from the spike glycoprotein of SARS-CoV-2, systems, and methods of using thereof for the treatment of viral infections (e.g., coronavirus disease 2019 (COVID-19)). |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 18/040531 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Original (OR) Class A61K 2039/55516 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009321 | Lu |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianqin Lu (Tucson, Arizona) |
| ABSTRACT | Described herein are compositions and methods for treating cancer. The compositions comprise sphingomyelin-conjugated cancer drugs which can be formed into nanovesicles. These nanovesicles can be loaded with additional doxorubicin-conjugated drugs to provide combination therapeutics. These compositions are efficacious for cancer treatments. |
| FILED | Tuesday, November 23, 2021 |
| APPL NO | 18/254068 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/6911 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009325 | REFETOFF et al. |
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| FUNDED BY |
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| APPLICANT(S) | PriZm, LLC (Chandler, Arizona); The University of Chicago (Chicago, Illinois); The University of Miami (Coral Gables, Florida); Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samuel REFETOFF (Chicago, Illinois); Roy WEISS (Miami Beach, Florida); Khemraj HIRANI (Chandler, Arizona); Clive SVENDSEN (Pacific Palisades, California); Pablo AVALOS (West Hollywood, California); Gad VATINE (Ramat Gan, Israel) |
| ABSTRACT | The present disclosure is directed to methods of treating Allan-Herndon-Dudley syndrome comprising administering 3,5-diiodothyropropionic acid (DITPA) to a subject in need thereof, and to administering gene therapy to the subject by introducing normal human MCT8 into the subject's cells in order to increase T3 in the subject's brain. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/350077 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 48/005 (20130101) Original (OR) Class A61K 48/0016 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009350 | Kuo |
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| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Catherine K. Kuo (College Park, Maryland) |
| ABSTRACT | The present invention relates to enhancing mechanical properties of tissue such as collagenous or collagen-containing or elastin-containing tissue (e.g., tendons, ligaments, and cartilage) and treating related musculoskeletal and non-musculoskeletal conditions or injuries. |
| FILED | Wednesday, May 03, 2023 |
| APPL NO | 18/311592 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0048 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/3834 (20130101) A61L 2300/254 (20130101) A61L 2300/414 (20130101) A61L 2430/06 (20130101) A61L 2430/10 (20130101) A61L 2430/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009460 | Yazdan-Shahmorad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Azadeh Yazdan-Shahmorad (Seattle, Washington); Zixuan Zhou (Seattle, Washington); Karam Khateeb (Seattle, Washington); Mona Rahimi (Seattle, Washington); Aryaman Gala (Seattle, Washington) |
| ABSTRACT | Techniques for treating acute ischemic stroke, and other neurological pathologies, are described herein. An example method includes identifying a portion of a brain including overactive neurons and outputting an electrical signal to at least one stimulation electrode disposed away from the portion of the brain by a distance in a range of about 0.5 mm to 1 cm. The electrical signal includes a low-frequency component including bursts having a frequency in a range of about 2 Hz to about 10 Hz. The electrical signal includes a high-frequency component comprising pulses having a frequency in a range of about 200 Hz to about 2 kHz. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/219047 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/36064 (20130101) A61N 1/36067 (20130101) A61N 1/36103 (20130101) Original (OR) Class A61N 1/36139 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009630 | Tian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bozhi Tian (Chicago, Illinois); Aleksander Prominski (Chicago, Illinois); Lingyuan Meng (Chicago, Illinois) |
| ABSTRACT | This disclosure relates to methods for modulating activity of cells and tissue with materials that are capable of being activated by an energy pulse, such methods useful for treating diseases. The disclosure also provides devices and systems suitable for use in such methods, particularly devices and systems having a carbon-based material comprising one or more monolithic porous carbon membranes. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 18/254301 |
| CURRENT CPC | Separation B01D 67/0058 (20130101) Original (OR) Class B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 71/021 (20130101) B01D 2325/0283 (20220801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010601 | SWENSON et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rolf SWENSON (Bethesda, Maryland); Alan REMALEY (Bethesda, Maryland); Zhen-Dan SHI (Bethesda, Maryland); Zhi-hong YANG (Bethesda, Maryland) |
| ABSTRACT | The disclosure provides methods of synthesizing very long chain fatty acids, including deuterated very long chain fatty acids. The fatty acids can by polyunsaturated fatty acids. The methods include the step of reacting a protected leaving group (L)-substituted saturated aliphatic group with a halo-substituted unsaturated aliphatic group to form a protected aliphatic group. The protected aliphatic group is deprotected to form an alcohol. The alcohol is then oxidized, thereby forming a very long chain fatty acid. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 18/042743 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 57/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010602 | AL-HORANI |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xavier University of Louisiana (New Orleans, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rami A. AL-HORANI (New Orleans, Louisiana) |
| ABSTRACT | The present disclosure is directed to compounds having Formula (I) and their enantiomers, wherein the definitions of R, Y1, Y2, W, X, Z, and n are provided in the disclosure. The disclosure is also directed to pharmaceutical compositions of the disclosed compounds, as well as their use for treatment of thrombosis and related conditions and complications. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/347724 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) Acyclic or Carbocyclic Compounds C07C 59/90 (20130101) Original (OR) Class C07C 69/734 (20130101) C07C 235/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010634 | LAWRENCE et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas J. LAWRENCE (Lutz, Florida); Harshani Rithma LAWRENCE (Lutz, Florida); Derek DUCKETT (Land O Lakes, Florida); Gary REUTHER (Temple Terrace, Florida) |
| ABSTRACT | The present disclosure provides anti-cancer compounds and uses thereof, more particularly inhibitors of ACK1 tyrosine kinase and their use in the treatment of cancer. |
| FILED | Monday, August 16, 2021 |
| APPL NO | 18/021320 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 403/12 (20130101) Original (OR) Class C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010641 | Contessa et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph N. Contessa (New Haven, Connecticut); Michael Van Zandt (New Haven, Connecticut) |
| ABSTRACT | The present disclosure includes compounds, compositions, and methods for preventing, ameliorating, and/or treating diseases associated with N-linked glycosylation and/or oligosaccharyltransferase function in a subject in need thereof. The methods comprise administering to the subject an effective amount of at least one compound and/or pharmaceutical composition of the disclosure. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 18/043436 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 417/12 (20130101) Original (OR) Class C07D 513/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010670 | Micalizio et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Glenn C. Micalizio (Norwich, Vermont); Arti B. Gaur (Hanover, New Hampshire) |
| ABSTRACT | The present disclosure relates to stereodefined polycyclic (e.g., tetracyclic) compounds that contain quaternary centers at one or multiple ring fusions, synthetic methods for preparing such compounds, and methods of using such compounds to treat a disease, such as a brain tumor and, particularly, a glioma. |
| FILED | Monday, September 18, 2023 |
| APPL NO | 18/468907 |
| CURRENT CPC | Steroids C07J 1/0055 (20130101) C07J 7/002 (20130101) C07J 75/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010683 | Egner et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Michael Egner (Westmont, Illinois); R. Blake Hill (Milwaukee, Wisconsin); Michael E. Widlansky (Fox Point, Wisconsin); Kelsey Meacham (Brookfield, Wisconsin) |
| ABSTRACT | The present disclosure provides inhibitory peptides of mitochondrial fission protein 1 (Fis1), polynucleotides and vectors encoding the peptides, and methods of using the peptides to treat diseases, including arterial diseases and vascular dysfunction associated with type 2 diabetes. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 18/252073 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/08 (20180101) Peptides C07K 7/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010685 | YAVIN et al. |
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| FUNDED BY |
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| APPLICANT(S) | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (Jerusalem, Israel); UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eylon YAVIN (Jerusalem, Israel); Daniel APPELLA (Rockville, Maryland) |
| ABSTRACT | The invention generally concerns a novel class of cyclopentane modified FIT-PNA (cpFIT-PNA) probes and uses thereof. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 18/252086 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) Peptides C07K 14/003 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010687 | Baker et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Baker (Seattle, Washington); Alexis Courbet (Seattle, Washington); Jesse Hansen (Seattle, Washington); Yang Hsia (Seattle, Washington); Neville Bethel (Seattle, Washington); Justin Kollman (Seattle, Washington) |
| ABSTRACT | Polypeptides that comprise axle or ring components of protein nanomachines, and kits and nanomachines including such polypeptides are disclosed herein. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931214 |
| CURRENT CPC | Peptides C07K 14/245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010694 | Hettiaratchi et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Marian Hettiaratchi (Eugene, Oregon); Jonathan Dorogin (Eugene, Oregon); Henry Hochstatter (Medford, Massachusetts); Veronica Spaulding (Harrisburg, Oregon); Alycia Galindo (Eugene, Oregon); Chandler Asnes (Eugene, Oregon); Justin Svendsen (Eugene, Oregon); Madeline Martin (Eugene, Oregon) |
| ABSTRACT | Provided are unique affibodies specific for bone morphogenetic protein 2 (BMP-2), vascular endothelial growth factor (VEGF), fibroblast growth factor 2 (FGF-2), platelet-derived growth factor (PDGF), granulocyte-macrophage colony-stimulating factor (GM-CSF), inteleukin-4 (IL-4), and glial derived neurotrophic factor (GDNF), and well as hydrogels that include the affibodies and the corresponding protein. Also provided are methods of using the hydrogels, for example to treat bone injury, wounds, and neuron injury. In some examples, the hydrogel includes at least two different affibodies specific for the same protein, but have different disassociation constants (KD). |
| FILED | Friday, June 23, 2023 |
| APPL NO | 18/340754 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 19/00 (20180101) Peptides C07K 14/51 (20130101) Original (OR) Class C07K 14/475 (20130101) C07K 14/535 (20130101) C07K 14/5406 (20130101) C07K 2318/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010838 | HELGASON et al. |
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| FUNDED BY |
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| APPLICANT(S) | VitroLabs Inc (Milpitas, California); King's College London (London, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ingvar HELGASON (South San Francisco, California); Dusko ILIC (London, United Kingdom) |
| ABSTRACT | Disclosed herein are synthetic leathers, artificial epidermal layers, artificial dermal layers, layered structures, products produced therefrom and methods of producing the same. |
| FILED | Wednesday, July 05, 2023 |
| APPL NO | 18/347349 |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 89/06 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0625 (20130101) C12N 5/0629 (20130101) C12N 5/0698 (20130101) C12N 11/02 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2502/13 (20130101) C12N 2502/091 (20130101) C12N 2502/094 (20130101) C12N 2506/45 (20130101) C12N 2533/30 (20130101) C12N 2533/54 (20130101) Chemical Treatment of Hides, Skins or Leather, e.g Tanning, Impregnating, Finishing; Apparatus Therefor; Compositions for Tanning C14C 3/02 (20130101) C14C 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010960 | Allbritton et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nancy L. Allbritton (Seattle, Washington); Yuli Wang (Lynnwood, Washington); Raehyun Kim (Chapel Hill, North Carolina) |
| ABSTRACT | A method for producing tissue constructs comprising two or more distinct regions, each of which comprises a different cell population or lineage is described. The method involves providing a support substrate or substrate assembly comprising two or more physically distinct regions, wherein the two or more physically distinct regions of the support substrate or substrate assembly are different from each other; and depositing/positioning one or more cells on the support substrate or substrate assembly. The cells can form a continuous monolayer with at least two zones, e.g., a proliferative zone and a nonproliferative zone, that can act as in vitro intestinal models. The models are two-dimensional, thus facilitating rapid and facile imaging. Systems comprising the tissue constructs and methods of using the constructs to study the effects of pharmaceuticals, nutraceuticals, and metabolites on intestinal cells are also described. |
| FILED | Friday, September 22, 2023 |
| APPL NO | 18/371636 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) Original (OR) Class C12M 25/04 (20130101) C12M 35/08 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010980 | Kaufman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan S. Kaufman (La Jolla, California); Kenta Yamamoto (La Jolla, California) |
| ABSTRACT | Engineered immune cells, optionally natural killer (NK) cells, comprising an inactivating mutation for an endogenous A-Disintegrin-And-Metalloproteinase 17 (ADAM 17) gene. ADAM17-deficient immune cells produced from stem cells, optionally, induced pluripotent stem cells (iPSCs), having enhanced antibody-dependent cellular cytotoxicity (ADCC). Pharmaceutical compositions comprising said engineered immune cells. Methods for making the engineered immune cell and pharmaceutical compositions, and methods of use are provided. |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 18/249991 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/545 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2863 (20130101) C07K 16/2887 (20130101) C07K 2317/732 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) Original (OR) Class C12N 9/6489 (20130101) C12N 2506/45 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 304/24086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010992 | Hekman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestem University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Katherine E. Hekman (Atlanta, Georgia); Jason A. Wertheim (Tucson, Arizona); Congcong He (Chicago, Illinois) |
| ABSTRACT | Provided herein are compositions and methods to promote longevity of induced pluripotent stem cell (iPSC)-derived endothelial cells (ECs) via autophagy. In particular, provided herein are AMP-activated protein kinase (AMPK) activators, such as ginsenosides (e.g., Rg2), and use thereof to increase longevity of iPSC-ECs by stimulating mTOR-independent ULK1-mediated autophagy. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/350161 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/06 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/545 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/507 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 2501/727 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010995 | Kawaoka et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Tokyo (Tokyo, Japan); Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Yuri Furusawa (Tokyo, Japan); Seiya Yamayoshi (Kanagawa, Japan) |
| ABSTRACT | Modified influenza virus neuraminidases are described herein that have stabilized NA tetramers which may improve vaccine production efficiency, thus improving the yield of vaccine viruses. |
| FILED | Thursday, August 03, 2023 |
| APPL NO | 18/365082 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/55566 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011000 | ELLINGTON et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew ELLINGTON (Austin, Texas); Inyup PAIK (Austin, Texas); Andre MARANHAO (Austin, Texas); Sanchita BHADRA (Austin, Texas); David WALKER (Austin, Texas); Phuoc NGO (Austin, Texas); Daniel DIAZ (Austin, Texas) |
| ABSTRACT | Disclosed are recombinant fusion proteins comprising a villin headpiece HP47 domain and a heterologous protein domain, such as, for example, a nucleic acid polymerase. Also disclosed are nucleic acids (e.g., DNA constructs) encoding the fusion protein, expression vectors and recombinant host cells for expression of the fusion protein, and methods of using the recombinant fusion proteins. |
| FILED | Wednesday, September 15, 2021 |
| APPL NO | 18/044909 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/127 (20130101) C12N 9/1247 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Enzymes C12Y 207/07007 (20130101) C12Y 207/07049 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011009 | GUNDERSON et al. |
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| FUNDED BY |
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| APPLICANT(S) | Encodia, Inc. (San Diego, California) |
| ASSIGNEE(S) | Encodia, Inc. (San Diego, California) |
| INVENTOR(S) | Kevin L. GUNDERSON (San Diego, California); Robert C. JAMES (San Diego, California); Lei SHI (San Diego, California); Stephen VERESPY, III (San Diego, California); Kevin DESAI (San Diego, California) |
| ABSTRACT | Provided herein are modified dipeptide cleavases for removing amino acid(s) from peptides, polypeptides, and proteins. Also provided are methods of using the modified dipeptide cleavases for treating polypeptides, and kits comprising the modified dipeptide cleavase. In some embodiments, the methods and the kits also include other components for macromolecule sequencing and/or analysis. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 18/016665 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011010 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zibo Chen (Pasadena, California); Michael B. Elowitz (Pasadena, California) |
| ABSTRACT | Disclosed herein include methods, compositions, and kits suitable for use in winner-take-all neural network computation in mammalian cells. In some embodiments, de novo designed protein heterodimers and engineered viral proteases are combined to implement a synthetic protein circuit that performs winner-take-all neural network computation. The synthetic protein circuit can include modules that compute weighted sums of input protein concentrations through reversible binding interactions, and allow for self-activation and mutual inhibition of protein components using irreversible proteolytic cleavage reactions. |
| FILED | Wednesday, July 05, 2023 |
| APPL NO | 18/347423 |
| CURRENT CPC | Peptides C07K 14/001 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/003 (20130101) C12N 9/506 (20130101) Original (OR) Class Enzymes C12Y 105/01003 (20130101) C12Y 304/22044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011021 | ISMAGILOV et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rustem F. ISMAGILOV (Pasadena, California); Matthew S. CURTIS (Pasadena, California); Mary ARRASTIA (Pasadena, California); David A. SELCK (Pasadena, California); Mitchell GUTTMAN (Pasadena, California) |
| ABSTRACT | Methods, systems and related compositions are provided to perform single-cell marking of a nucleic acid and/or protein in a sample based on in-cell or in-organelle barcoding of nucleic acid and/or protein complexes of the cell or organelle; the methods and systems herein described are configured to provide in-cell or in-organelle single-cell marked nucleic acid and/or protein complexes comprising a single-cell, cell-specific, or a single-cell organelle-specific marker. |
| FILED | Thursday, February 23, 2023 |
| APPL NO | 18/173735 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 2200/16 (20130101) B01L 2200/027 (20130101) B01L 2200/141 (20130101) B01L 2300/161 (20130101) B01L 2300/0816 (20130101) B01L 2300/0861 (20130101) B01L 2400/065 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6855 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011025 | EBERWINE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Agilent Technologies, Inc. (Santa Clara, California); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Agilent Technologies, Inc. (Santa Clara, California); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | James EBERWINE (Philadelphia, Pennsylvania); Jae-Hee LEE (Philadelphia, Pennsylvania); Jifen LI (Philadelphia, Pennsylvania); Stephen FISHER (Philadelphia, Pennsylvania); Youtao LU (Philadelphia, Pennsylvania); Junhyong KIM (Philadelphia, Pennsylvania); Jai-Yoon SUL (Philadelphia, Pennsylvania); Jinchun WANG (Santa Clara, California); Mimi HEALY (Santa Clara, California) |
| ABSTRACT | Provided herein are compositions and methods to assess the genomic landscape of fixed cells using light activated oligonucleotides that can be directed to the nucleus, mitochondria, or cytoplasm of fixed cells and that, upon activation, can be extended for in situ copying of nuclear single-stranded DNA (i.e., open chromatin), open mitochondrial DNA, and/or cytoplasmic RNA into barcoded complementary DNA. These methods also provide for gene specific 3D chromatin structural niche analysis. |
| FILED | Thursday, June 15, 2023 |
| APPL NO | 18/335896 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011034 | Yoo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Yoo (St. Louis, Missouri); Youngmi Oh (St. Louis, Missouri) |
| ABSTRACT | The present invention relates to compositions and methods for modulating miRNAs acitivity in a population of cells or a subject. More particularly, the invention relates to inhibiting the expression and/or activity of miR-29b-3p to enhance neuronal survival during neurodegeneration. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/348263 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/64 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011046 | Delgoffe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Greg M. Delgoffe (Pittsburgh, Pennsylvania); Andrew P. Hinck (Pittsburgh, Pennsylvania); Kristin DePeaux (Pittsburgh, Pennsylvania) |
| ABSTRACT | Oncolytic viruses encoding a recombinant form of TGF-β engineered to prevent homodimerization and recruitment of TGF-β receptor I are described. The engineered TGF-β monomers function as dominant-negative TGF-β inhibitors. Oncolytic viruses encoding a TGF-β monomer can be used for cancer immunotherapy to inhibit the immunosuppressive tumor microenvironment. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 18/022936 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/768 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/495 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011047 | Barry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); The UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Peter Barry (Davis, California); Dennis Hartigan-O'Connor (Kensington, California); Ellen Sparger (Davis, California); William Chang (Sacramento, California); Mark Walter (Birmingham, Alabama); Corey Miller (San Francisco, California) |
| ABSTRACT | In one aspect, the present invention provides recombinant polynucleotides. In some embodiments, the recombinant polynucleotides comprise a cytomegalovirus (CMV) genome, or a portion thereof, and a nucleic acid sequence encoding an antigen, wherein the CMV genome or portion thereof comprises a mutation within a interleukin-10-like gene sequence. Methods for preventing and treating diseases such as infectious diseases and cancer are also provided herein. |
| FILED | Monday, December 12, 2022 |
| APPL NO | 18/064809 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 39/00119 (20180801) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) A61P 35/00 (20180101) Peptides C07K 14/005 (20130101) C07K 14/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2710/16122 (20130101) C12N 2710/16134 (20130101) C12N 2710/16143 (20130101) C12N 2740/15034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011049 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Peter Cabeceiras (Boston, Massachusetts) |
| ABSTRACT | Human-derived virus-like particles (heVLPs), comprising a membrane comprising a phospholipid bilayer with one or more HERV-derived envelope proteins on the external side; one or more HERV-derived GAG proteins in the heVLP core, and a cargo molecule, e.g., a biomolecule and/or chemical cargo molecule, disposed in the core of the heVLP on the inside of the membrane, wherein the heVLP does not comprise a gag protein, except for gag proteins that are encoded in the human genome or gag proteins that are encoded by a consensus sequence that is derived from gag proteins found in the human genome, and methods of use thereof for delivery of the cargo molecule to cells. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/351674 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2740/10023 (20130101) C12N 2740/10042 (20130101) C12N 2740/10052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011050 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Peter Cabeceiras (Boston, Massachusetts) |
| ABSTRACT | Human-derived virus-like particles (heVLPs), comprising a membrane comprising a phospholipid bilayer with one or more HERV-derived envelope proteins on the external side; one or more HERV-derived GAG proteins in the heVLP core, and a cargo molecule, e.g., a biomolecule and/or chemical cargo molecule, disposed in the core of the heVLP on the inside of the membrane, wherein the heVLP does not comprise a gag protein, except for gag proteins that are encoded in the human genome or gag proteins that are encoded by a consensus sequence that is derived from gag proteins found in the human genome, and methods of use thereof for delivery of the cargo molecule to cells. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/351689 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2740/10023 (20130101) C12N 2740/10042 (20130101) C12N 2740/10052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011055 | Shendure et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jay Ashok Shendure (Seattle, Washington); Wei Chen (Seattle, Washington); Junhong Choi (Seattle, Washington) |
| ABSTRACT | Disclosed are methods and related compositions for genomic editing. In one aspect, methods of editing double stranded DNA (dsDNA) use first and second editing complexes specific for first and second target sequences on the sense and antisense strands of the dsDNA molecule, respectively. Each editing complex comprises an extended guide RNA associated with a fusion editor protein, which comprises a functional nickase domain and a functional reverse transcriptase domain. The respective guide RNAs guide their associated fusion editor proteins to the dsDNA, which implement single stranded breaks on opposite strands of the dsDNA. The respective reverse transcriptase domains generate 3′ overhangs. Repair of the dsDNA excises the portion of dsDNA disposed between the two single-stranded breaks. A variety of configurations and applications of the method are disclosed, providing flexible, facile, efficient, and precise methods to impose genetic manipulations. |
| FILED | Thursday, November 04, 2021 |
| APPL NO | 18/251514 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1241 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011070 | Alavi Khorassani Moghadam |
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| FUNDED BY |
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| APPLICANT(S) | 712 North Inc. (Oakland, California) |
| ASSIGNEE(S) | 712 North Inc. (Oakland, California) |
| INVENTOR(S) | Marcel V. Alavi Khorassani Moghadam (Berkeley, California) |
| ABSTRACT | The present invention relates to a reporter for measuring OMA1 protease activity comprising a targeting sequence and a signal producing domain, wherein the targeting sequence is also the sequence recognized by OMA1. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 18/019733 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Original (OR) Class C12Q 1/66 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011085 | HE et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Chuan HE (Chicago, Illinois); Ji NIE (Chicago, Illinois); Xiao-Long CUI (Chicago, Illinois) |
| ABSTRACT | The methods, compositions, and kits of the disclosure provide a novel approach for a whole genome, unbiased DNA analysis method that can be performed on limited amounts of DNA. can be used to analyze DNA to determine its modification status. Aspects of the disclosure relate to a method for amplifying bisulfite-treated deoxyribonucleic acid (DNA) molecules comprising: (a) ligating an adaptor to the DNA molecules, wherein the adaptor comprises a RNA polymerase promoter comprising bisulfite-protected cytosines; (b) treating the ligated DNA molecules with bisulfite; (c) hybridizing the bisulfite-treated DNA molecules with a primer; (d) extending the hybridized primer to make double stranded DNA; and (e) in vitro transcribing the double-stranded DNA to make RNA. |
| FILED | Monday, November 21, 2022 |
| APPL NO | 18/057424 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6865 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011089 | BOYANOV et al. |
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| FUNDED BY |
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| APPLICANT(S) | Illumina, Inc. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | BOYAN BOYANOV (San Diego, California); JEFFREY G MANDELL (San Diego, California); KEVIN L GUNDERSON (San Diego, California); JINGWEI BAI (San Diego, California); LIANGLIANG QIANG (San Diego, California); BRADLEY BAAS (Madison, Wisconsin) |
| ABSTRACT | The disclosure provides detection apparatus having one or more nanopores, methods for making apparatus having one or more nanopore and methods for using apparatus having one or more nanopores. Uses include, but are not limited to detection and sequencing of nucleic acids. |
| FILED | Thursday, June 29, 2023 |
| APPL NO | 18/344035 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44782 (20130101) G01N 27/44791 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011096 | Khatri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Purvesh Khatri (Menlo Park, California); Timothy E. Sweeney (Truckee, California) |
| ABSTRACT | Biomarkers and methods of using them for aiding diagnosis, prognosis, and treatment of critically ill patients are disclosed. In particular, the invention relates to the use of biomarkers for prognosis of mortality in critically ill patients with sepsis, severe trauma, or burns. |
| FILED | Wednesday, February 08, 2023 |
| APPL NO | 18/107477 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011100 | McDonald et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Memorial Sloan Kettering Cancer Center (New York, New York); Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Oliver McDonald (Baltimore, Maryland); Xin Li (Baltimore, Maryland); Christine A. Iacobuzio-Donahue (Baltimore, Maryland); Andrew P. Feinberg (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to a method of identifying epigenetic reprogramming. Identifying epigenetic reprogramming comprises detecting large organized heterochromatin lysine (K)-9 modified domains (LOCKs) and large DNA hypomethylated blocks in a sample containing DNA from a subject having cancer, for example, PDAC. |
| FILED | Tuesday, August 01, 2023 |
| APPL NO | 18/229064 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6811 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011103 | GAY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, None) |
| INVENTOR(S) | Carl M. GAY (Houston, Texas); Lauren A. BYERS (Houston, Texas); John V. HEYMACH (Houston, Texas) |
| ABSTRACT | Provided herein are methods for determining a subtype of a small cell lung cancer in a patient based on the express status of ASCL1, NEUROD1, and POU2F3, which are expressed in a mutually exclusive fashion. The subtype of the cancer can be used to determine the sensitivity of the cancer to certain anti-cancer therapies. As such, also provided are methods of treating patients having small cell lung cancer based on the subtyping results. |
| FILED | Thursday, June 29, 2023 |
| APPL NO | 18/344010 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011107 | Harris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Reuben S. Harris (Helotes, Texas); Seyed Arad Moghadasi (Minneapolis, Minnesota); Jordan Becker (Saint Paul, Minnesota) |
| ABSTRACT | Materials and methods for identifying inhibitors of protease activity are provided herein. For example, this document provides materials and methods that can be used to identify inhibitors of a protease (e.g., SARS-CoV-2 Mpro). |
| FILED | Friday, November 12, 2021 |
| APPL NO | 18/035021 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) C12Q 1/6897 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/8107 (20130101) G01N 2333/9513 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011900 | Potyrailo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Baokai Cheng (Schenectady, New York); Aghogho Atemu Obi (Weston, Florida); Christopher Collazo-Davila (Clifton Park, New York); Richard Jean-Luc St. Pierre (Clifton Park, New York) |
| ABSTRACT | Gas sensors are disclosed having an on-board, low-power data processor that uses multivariable gas classification and/or gas quantitation models to perform on-board data processing to resolve two or more gases in a fluid sample. To reduce computational complexity, the gas sensor utilizes low-power-consumption multivariable data analysis algorithms, inputs from available on-board sensors of ambient conditions, inputs representing contextual data, and/or excitation responses of a gas sensing material to select suitable gas classification and/or gas quantitation models. The data processor can then utilize these gas classification and quantitation models, in combination with measured dielectric responses of a gas sensing material of the gas sensor, to determine classifications and/or concentrations of two or more gases in a fluid sample, while consuming substantially less power than would be consumed if a global comprehensive model were used instead. Thus, the data processor is utilized for linear, nonlinear, and non-monotonic multivariate regressions. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859904 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3504 (20130101) Original (OR) Class G01N 33/0006 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011962 | Potyrailo et al. |
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| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Baokai Cheng (Schenectady, New York) |
| ABSTRACT | A system and a method for multi-gas sensing using dielectric excitation of a single sensing material at multiple operating temperatures. By measuring dielectric excitation responses of the gas sensing material, enhanced multi-gas differentiation and differentiation can be achieved using fewer operating temperatures than would be used by the same MOS gas sensing material configured to perform multi-gas differentiation based on resistance responses alone. The disclosed gas sensors and gas sensing techniques enable improved response linearity, improved dynamic range, and reduced computational resource consumption for multi-gas quantitation relative to traditional resistance-based gas sensing methods. Present embodiments unexpectedly demonstrate MOS-based gas sensors that can differentiate between different gases using responses collected using at least two different operating temperatures, wherein this differentiation is superior in the differentiation between different gases and in baseline stability, as compared to the resistance response of the same gas sensing material at more than two operating temperatures. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859887 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/123 (20130101) G01N 33/0032 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011985 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FZata, Inc. (Halethorpe, Moldova) |
| ASSIGNEE(S) | FZata, Inc. (Halethorpe, Maryland) |
| INVENTOR(S) | Zhiyong Yang (West Friendship, Maryland); Hua Yu (Columbia, Maryland) |
| ABSTRACT | Described herein, are methods of detecting neutralizing antibodies that bind to Clostridioides difficile (C. diff) toxin B (TcdB), prognosing the disease severity of Clostridioides difficile infection (CDI) and the risk of primary and recurrent CDI, as well as providing a guide for clinical practice. Also described herein are kits for performing the methods of this disclosure. |
| FILED | Tuesday, October 19, 2021 |
| APPL NO | 18/032657 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) Original (OR) Class G01N 2333/33 (20130101) G01N 2469/20 (20130101) G01N 2470/12 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011986 | KUHN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kristine KUHN (Denver, Colorado); Michael V. HOLERS (Denver, Colorado); Kevin DEANE (Denver, Colorado); Kristen DEMORUELLE (Goldern, Colorado); Jill NORRIS (Denver, Colorado); Meagan CHRISWELL (Aurora, Colorado); William ROBINSON (Palo Alto, California) |
| ABSTRACT | Therapeutic and prophylactic therapies for rheumatoid arthritis are provided, as are related pharmaceutical compositions. Methods provide for the early detection of subjects at risk of developing rheumatoid arthritis, thus allowing for early intervention, and include methods of sample preparation. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 18/251915 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/40 (20130101) A61K 39/0208 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) Original (OR) Class G01N 2469/20 (20130101) G01N 2800/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011990 | SANKAR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Karthika SANKAR (Boston, Massachusetts); Scott SCHAUS (Boston, Massachusetts); James GALAGAN (Needham, Massachusetts); Catherine KLAPPERICH (Brookline, Massachusetts); John CONNOR (Newton, Massachusetts); Mark GRINSTAFF (Brookline, Massachusetts); Keith HEARON (Boston, Massachusetts) |
| ABSTRACT | The systems, methods, devices and kits disclosed herein be used to determine the presence and/or level a target analyte(s) in a biological sample, wherein the analyte(s) is associated with a pathogenic (e.g., a viral antigen or whole virus) or otherwise altered physiological condition (e.g., pregnancy). In certain embodiments, the systems, methods, devices and kits provide one or more improved properties relative to the RT-PCT and lateral flow antibody assays known in the art for the detection of SARS-CoV-2, including but not limited to, assay time, ease of use, risk of infection, accuracy, specificity, selectivity, limit of detection of the assay, quantitative detection and the effect of common interferents to the sensor output, cost, simplicity or a combination thereof. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 18/016497 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3272 (20130101) G01N 27/3276 (20130101) G01N 27/3277 (20130101) G01N 27/3278 (20130101) G01N 33/5308 (20130101) G01N 33/54386 (20130101) G01N 33/56983 (20130101) Original (OR) Class G01N 2333/11 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011991 | Abdel-Mohsen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohamed Abdel-Mohsen (Wynnewood, Pennsylvania) |
| ABSTRACT | Compositions, kits and methods for diagnosing and treating an increased risk of moderate to severe COVID-19 disease involves a composition comprising at least one reagent capable of detecting, binding, specifically complexing with, or measuring the level of one of a subject marker in a sample. Optionally, a composition of the invention further comprises a reagent capable of detecting, binding, specifically complexing with, or measuring the expression of a subject biomarker. |
| FILED | Thursday, November 11, 2021 |
| APPL NO | 18/252115 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) Original (OR) Class G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012002 | Ros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alexandra Ros (Phoenix, Arizona); Jorvani Cruz Villarreal (Tempe, Arizona); Ana Egatz-Gomez (Phoenix, Arizona); Todd Sandrin (Phoenix, Arizona); Paul Coleman (Fountain Hills, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandra Ros (Phoenix, Arizona); Jorvani Cruz Villarreal (Tempe, Arizona); Ana Egatz-Gomez (Phoenix, Arizona); Todd Sandrin (Phoenix, Arizona); Paul Coleman (Fountain Hills, Arizona) |
| ABSTRACT | Described herein are systems and methods for a microfluidic immunoassay for in situ mass spectrometry analysis of intracellular protein biomarkers in tissue. In some embodiments, the tissue may comprise human brain tissue. In some embodiments, the protein biomarkers may comprise Aβ species comprising monomers and oligomers of Aβ1-42, Aβ1-40, Aβ1-39, Aβ2-43, or combinations thereof. In some embodiments, the systems and methods may comprise laser capture microdissection (LCM) and matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. |
| FILED | Thursday, June 15, 2023 |
| APPL NO | 18/335713 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 2300/049 (20130101) B01L 2300/0816 (20130101) B01L 2400/0638 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 33/5304 (20130101) G01N 33/6851 (20130101) Original (OR) Class G01N 2001/284 (20130101) G01N 2333/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012008 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arpana Gupta (Los Angeles, California); Emeran A. Mayer (Los Angeles, California); Vadim Osadchiy (Los Angeles, California) |
| ABSTRACT | The present application relates to compositions and methods for diagnosing patients with a history of early-life adversity (ELA), and for preventing, treating, or reducing psychological distress in patients with a history of ELA. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 18/034570 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/5308 (20130101) G01N 33/6848 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2800/7042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012012 | HAY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meredith HAY (Tucson, Arizona); John KONHILAS (Tucson, Arizona); Christina HOYER-KIMURA (Tucson, Arizona); Thomas BEACH (Sun City, Arizona); Geidy SERRANO (Sun City, Arizona); Eric REIMAN (Phoenix, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Meredith HAY (Tucson, Arizona); John KONHILAS (Tucson, Arizona); Christina HOYER-KIMURA (Tucson, Arizona); Thomas BEACH (Sun City, Arizona); Geidy SERRANO (Sun City, Arizona); Eric REIMAN (Phoenix, Arizona) |
| ABSTRACT | The present invention provides compositions and methods useful in the diagnosis and treatment of a variety of cognitive impairments including vascular cognitive impairment and dementia, and Alzheimer's Disease. In one particular embodiment, the level of the neurofilament light protein and/or phosphorylated tau (e.g., p-tau181) is used to diagnose a cognitive impairment or monitor the efficacy of a therapy. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 18/039641 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 14/515 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012077 | Annio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Siemens Healthcare GmbH (Erlangen, Germany); Centre National de la Recherche Scientifique (CNRS) (Paris, France); Institut National de La Sante et de la Recherche Medicale (INSERM) (Paris, France); King's College London (London, United Kingdom); Department of Health and Human Services (Bethesda, Maryland); UNIV PARIS XIII PARIS-NORD VILLETANEUSE (Villetaneuse, France); Universite de Paris (Paris, France) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Giacomo Annio (Mola Di Bari Ba, Italy); Verena Müller-Reinwald (Hilpolstein, Germany); Ralph Sinkus (Parmain, France); Omar Darwish (London, United Kingdom); Wilfried Schnell (Forchheim, Germany); Tamara Elisabeth Falkner (Schwabach, Germany); Ahmed M. Gharib (Bethesda, Maryland) |
| ABSTRACT | The present disclosure is directed to a motor for a magnetic resonance (MR) tomography room, to a patient table for the MR room, to a MR elastography device, and to a MR tomography device. A MR tomography device for a MR elastography imaging protocol is arranged within the MR tomography room, and includes a rotational drive for supplying rotational energy to power a MR elastography transducer usable during the MR elastography imaging protocol, and a support structure. The rotational drive comprises a terminal for connecting the MR elastography transducer to the rotational drive, and a bearing means configured such that the position of the terminal relative to the support structure is adaptable along a trajectory predetermined by the bearing means. The rotational drive is mounted to the support structure via the bearing means. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/474332 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/704 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/48 (20130101) Original (OR) Class G01R 33/56358 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012080 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Yi Wang (New York, New York); Zhe Liu (New York, New York); Jinwei Zhang (New York, New York); Qihao Zhang (New York, New York); Junghun Cho (New York, New York); Pascal Spincemaille (New York, New York) |
| ABSTRACT | Exemplary methods for quantitative mapping of physical properties, systems and computer-accessible medium can be provided to generate images of tissue magnetic susceptibility, transport parameters and oxygen consumption from magnetic resonance imaging data using the Bayesian inference approach, which minimizes a data fidelity term under a constraint of a structure prior knowledge. The data fidelity term is constructed directly from the magnetic resonance imaging data. The structure prior knowledge can be characterized from known anatomic images using image feature extraction operation or artificial neural network. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining physical properties associated with at least one structure. |
| FILED | Monday, September 25, 2023 |
| APPL NO | 18/474048 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/7221 (20130101) A61B 5/7267 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) Original (OR) Class G01R 33/56536 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013800 | Mesgarani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nima Mesgarani (New York, New York); Yi Luo (New York, New York); James O'Sullivan (New York, New York); Zhuo Chen (New York, New York) |
| ABSTRACT | Disclosed are devices, systems, apparatus, methods, products, and other implementations, including a method comprising obtaining, by a device, a combined sound signal for signals combined from multiple sound sources in an area in which a person is located, and applying, by the device, speech-separation processing (e.g., deep attractor network (DAN) processing, online DAN processing, LSTM-TasNet processing, Conv-TasNet processing), to the combined sound signal from the multiple sound sources to derive a plurality of separated signals that each contains signals corresponding to different groups of the multiple sound sources. The method further includes obtaining, by the device, neural signals for the person, the neural signals being indicative of one or more of the multiple sound sources the person is attentive to, and selecting one of the plurality of separated signals based on the obtained neural signals. The selected signal may then be processed (amplified, attenuated). |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/228239 |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 17/26 (20130101) G10L 25/30 (20130101) Original (OR) Class G10L 25/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013853 | BAKER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David BAKER (Seattle, Washington); Basile WICKY (Seattle, Washington); Lukas MILLES (Seattle, Washington); Alexis COURBET (Seattle, Washington); Robert RAGOTTE (Seattle, Washington); Elias KINFU (Seattle, Washington); Sam TIPPS (Seattle, Washington); Justas DAUPARAS (Seattle, Washington); Ryan KIBLER (Seattle, Washington) |
| ABSTRACT | Polypeptide are providing that are at least 50% identical to the amino acid sequence selected from the group consisting of SEQ ID NOS:1-37, cyclic homo-oligomers of the polypeptides, and uses thereof. |
| FILED | Friday, July 07, 2023 |
| APPL NO | 18/348528 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/20 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240008938 | Farritor et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Erik Mumm (Longmont, Colorado); Philip Chu (Friendswood, Texas); Nishant Kumar (Bergenfield, New Jersey); Jason Dumpert (Omaha, Nebraska); Yutaka Tsutano (Campbell, California) |
| ABSTRACT | The embodiments disclosed herein relate to various medical device components, including components that can be incorporated into robotic and/or in vivo medical devices. Certain embodiments include various modular medical devices for in vivo medical procedures. |
| FILED | Monday, April 03, 2023 |
| APPL NO | 18/194723 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/29 (20130101) A61B 17/00234 (20130101) A61B 34/00 (20160201) A61B 34/30 (20160201) Original (OR) Class A61B 34/37 (20160201) A61B 90/30 (20160201) A61B 2017/2906 (20130101) A61B 2034/302 (20160201) A61B 2217/005 (20130101) A61B 2217/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009007 | van der Merwe et al. |
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| FUNDED BY |
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| APPLICANT(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dirk Albertus van der Merwe (Canterbury, New Hampshire); Gregory R. Lanier (Manchester, New Hampshire); John M. Kerwin (Manchester, New Hampshire); Gerald M. Guay (Greenville, New Hampshire); N. Christopher Perry (Manchester, New Hampshire); Susan D. Dastous (Litchfield, New Hampshire) |
| ABSTRACT | A control system for control of a prosthetic device having a plurality of actuators receives an orientation signal indicative of a desired movement. The control system evaluates whether the prosthetic device may move as desired with a current angle of rotation and commands at least one actuator to move the prosthetic device as desired by maintaining the current angle of rotation or by adjusting the angle of rotation if the prosthetic device cannot move as desired with the current angle. The control system may alternate between commanding a first subset of actuators and a second subset of actuators each time the orientation signal is indicative of a neutral position. The control system may include a position sensor and a compliance sensor and may command at least one actuator based on a combination of positional control using the position sensor and force control using the compliance sensor. |
| FILED | Monday, May 01, 2023 |
| APPL NO | 18/309931 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/70 (20130101) Original (OR) Class A61F 2/581 (20130101) A61F 2/582 (20130101) A61F 2/583 (20130101) A61F 2/585 (20130101) A61F 2/586 (20130101) A61F 2002/5018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009269 | SEARSON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Peter Charles SEARSON (Baltimore, Maryland); Kalina HRISTOVA (Baltimore, Maryland); Raleigh LINVILLE (Baltimore, Maryland); Alexander KOMIN (Baltimore, Maryland); Piotr WALCZAK (Baltimore, Maryland) |
| ABSTRACT | The present disclosure is directed to a composition or combination comprising at least one membrane-active peptide, such as melittin, and at least one therapeutic and/or diagnostic agent. Methods of using the membrane-active peptides of the disclosure to open a blood-brain barrier and to deliver a therapeutic and/or a diagnostic agent to a central nervous system (CNS) of a subject in need thereof are also provided. When administered as an intra-arterial injection into the cerebrovasculature, membrane-active peptides, such as melittin, support reversible blood-brain barrier opening without neurological damage |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 18/253084 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/1767 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/005 (20130101) A61M 2210/0693 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009320 | FLOREK et al. |
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| FUNDED BY |
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| APPLICANT(S) | DEPUY SYNTHES PRODUCTS, INC. (Raynham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles FLOREK (West Chester, Pennsylvania); Eric COZZONE (Glenmoore, Pennsylvania); David A. ARMBRUSTER (West Chester, Pennsylvania) |
| ABSTRACT | The present disclosure is directed to an organogel drug depot for use in a non-sterile environment and application to a non-sterile open wound site. The present disclosure is also directed to an organogel drug depot for use in delivering an active agent to a surgical site, such as an implant site, for instance an orthopedic implant site. In a further embodiment, there is disclosed a system for preparing an organogel drug depot including an organogel matrix comprising an organogelator and a biocompatible organic solvent, an active agent comprising solid particles, a container including at least one wall having an outer surface and defining a volume capable of containing the organogel matrix and active agent solid particles, and a heating component configured to contact the outer surface and supply an amount of heat to the container. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 18/253461 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/28 (20130101) A61K 47/44 (20130101) A61K 47/6903 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009346 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xuanhe Zhao (Aliston, Massachusetts); Hyunwoo Yuk (Cambridge, Massachusetts); Heejung Roh (Cambridge, Massachusetts); Aristidis Veves (Westwood, Massachusetts); Georgios Theocharidis (Cambridge, Massachusetts) |
| ABSTRACT | A shape memory adhesive material for adhering and contracting wounds, particularly diabetic wounds, to facilitate their closure and healing. The shape memory adhesive is pre-stretched and dried to provide an adhesive structure with a pre-programmed strain, wherein the adhesive is capable of rapid robust adhesion followed by predictive contraction upon contact with a wet surface. According to preferred embodiments, the shape memory adhesive material includes a combination of one or more hydrophilic polymers or copolymers, one or more amine coupling group, and one or more cross linkers. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/669442 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/008 (20130101) Original (OR) Class A61L 26/0033 (20130101) A61L 26/0038 (20130101) A61L 26/0052 (20130101) A61L 26/0066 (20130101) A61L 26/0095 (20130101) A61L 2400/16 (20130101) A61L 2430/34 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 11/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009630 | Tian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bozhi Tian (Chicago, Illinois); Aleksander Prominski (Chicago, Illinois); Lingyuan Meng (Chicago, Illinois) |
| ABSTRACT | This disclosure relates to methods for modulating activity of cells and tissue with materials that are capable of being activated by an energy pulse, such methods useful for treating diseases. The disclosure also provides devices and systems suitable for use in such methods, particularly devices and systems having a carbon-based material comprising one or more monolithic porous carbon membranes. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 18/254301 |
| CURRENT CPC | Separation B01D 67/0058 (20130101) Original (OR) Class B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 71/021 (20130101) B01D 2325/0283 (20220801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010321 | Walter |
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| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew W. Walter (Troy, Missouri) |
| ABSTRACT | Pyrotechnic devices and firing mechanisms for aircraft canopy jettison are disclosed herein. An example firing mechanism includes a housing defining a first bore, a second bore, and a channel between the first bore and the second bore, a primary charge disposed in the second bore, a closure disc between the second bore and the channel, and a firing pin assembly disposed in the first bore. The firing pin assembly includes a percussion primer and a firing pin piston including a piston body, a firing pin extending from the piston body, and a piercing pin extending from the piston body. In response to a firing signal, the firing pin piston is moved toward the primary charge such that the piercing pin punctures the closure disc and the firing pin engages the percussion primer to ignite the primary charge. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860785 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/32 (20130101) Original (OR) Class B64C 1/1476 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010330 | Monahan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| ASSIGNEE(S) | LOCKHEED MARTIN CORPORATION (Bethesda, Maryland) |
| INVENTOR(S) | Jay Benjamin Monahan (Toms River, New Jersey); Erez Eller (Oakville, Connecticut) |
| ABSTRACT | A method for controlling a rotary wing aircraft includes determining a measured airspeed of the rotary wing aircraft based on data from a pitot probe, determining an estimated airspeed of the rotary wing aircraft based on rotor control commands, and determining a blended airspeed based on both the measured airspeed and the estimated airspeed. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860745 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/00 (20130101) Original (OR) Class Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/00 (20130101) B64D 2045/0085 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010575 | Cook et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Gary Cook (Beavercreek, Ohio); Ronald W. Stites (Beavercreek, Ohio) |
| ABSTRACT | A doped substrate having a substrate comprising at least one of a glass material, a single crystal material, a poly-crystalline material, a ceramic material, or a semiconductor material. The doped substrate includes a dopant comprising one or more transition metals, one or more rare earth elements, or a combination of both, the doped substrate characterized in that a spectral laser output of the doped substrate exhibits a nominally single frequency having a linewidth less than about 5 nm. |
| FILED | Friday, September 22, 2023 |
| APPL NO | 18/472560 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/176 (20130101) H01S 3/1603 (20130101) Original (OR) Class H01S 5/0213 (20130101) H01S 5/305 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010640 | Bender et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aaron M. Bender (Spring Hill, Tennessee); Matthew Spock (Nashville, Tennessee); Melissa A. Korkmaz-Vaisys (Nashville, Tennessee); Craig W. Lindsley (Brentwood, Tennessee); P. Jeffrey Conn (Nashville, Tennessee) |
| ABSTRACT | Disclosed herein are 6-((octahydrocyclopenta[c]pyrrol-5-yl)amino)pyridazin-3-yl-substituted pyridinones, pyrimidinones, and pyridazinones, useful as antagonists of the muscarinic acetylcholine receptor M4 (mAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating disorders using the compounds and compositions. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 18/253094 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/14 (20130101) C07D 405/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010694 | Hettiaratchi et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Marian Hettiaratchi (Eugene, Oregon); Jonathan Dorogin (Eugene, Oregon); Henry Hochstatter (Medford, Massachusetts); Veronica Spaulding (Harrisburg, Oregon); Alycia Galindo (Eugene, Oregon); Chandler Asnes (Eugene, Oregon); Justin Svendsen (Eugene, Oregon); Madeline Martin (Eugene, Oregon) |
| ABSTRACT | Provided are unique affibodies specific for bone morphogenetic protein 2 (BMP-2), vascular endothelial growth factor (VEGF), fibroblast growth factor 2 (FGF-2), platelet-derived growth factor (PDGF), granulocyte-macrophage colony-stimulating factor (GM-CSF), inteleukin-4 (IL-4), and glial derived neurotrophic factor (GDNF), and well as hydrogels that include the affibodies and the corresponding protein. Also provided are methods of using the hydrogels, for example to treat bone injury, wounds, and neuron injury. In some examples, the hydrogel includes at least two different affibodies specific for the same protein, but have different disassociation constants (KD). |
| FILED | Friday, June 23, 2023 |
| APPL NO | 18/340754 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 19/00 (20180101) Peptides C07K 14/51 (20130101) Original (OR) Class C07K 14/475 (20130101) C07K 14/535 (20130101) C07K 14/5406 (20130101) C07K 2318/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010970 | Oh |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Julia Oh (Bar Harbor, Maine) |
| ABSTRACT | Provided herein are antimicrobial biosensors for skin for treating Staphylococcus aureus Type I, Type II, Type III, and/or Type IV infection. In some embodiments, the antimicrobial biosensors are expressed in Staphylococcus epidermidis cells. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 18/032845 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1729 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/569 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011065 | Stephanopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas Stephanopoulos (Scottsdale, Arizona); Minghui Liu (Chandler, Arizona) |
| ABSTRACT | A photocaged DNA nano-tweezer and methods of using said photocaged DNA nano-tweezer are described. In particular, provided herein is a DNA nano-tweezer comprising a hairpin with a single-stranded loop that comprises a first arm and a second arm; and a trigger strand complementary to the single-stranded loop and comprising at least one photocaged residue with a protecting group. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/327434 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 2310/122 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011077 | Schulman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rebecca B. Schulman (Baltimore, Maryland); Daniel Siegal (Baltimore, Maryland); Yi Li (Baltimore, Maryland); Samuel Schaffter (Baltimore, Maryland); Joanna Schneider (Baltimore, Maryland) |
| ABSTRACT | Described are systems comprising nucleic acid nanostructures, e.g., nanotubes, for use in detecting biological agents. The systems comprise a nucleic acid nanotube, nucleic acid nanotube seed, a plurality nucleic acid nanotube monomers, or a combination there of; a nucleic acid nanotube terminus; and an activation strand comprising a single-stranded nucleic acid comprising a first sequence complementary to a portion of the nucleic acid nanotube, nucleic acid nanotube seed, nucleic acid nanotube monomers and a second sequence complementary to a portion of the nucleic acid nanotube terminus. Devices, kits, and methods comprising the systems are also described. |
| FILED | Monday, October 04, 2021 |
| APPL NO | 18/247794 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011084 | Jewett et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael C. Jewett (Evanston, Illinois); Michael J. Hammerling (Evanston, Illinois) |
| ABSTRACT | Disclosed are methods, components, compositions, and kits for preparing DNA molecules by reverse transcribing RNA templates that comprise modified ribonucleosides. The disclosed methods, components, compositions, and kits utilize or comprise thermostable enzymes having RNA-dependent DNA polymerase activity, otherwise referred to as reverse transcriptases. |
| FILED | Tuesday, November 02, 2021 |
| APPL NO | 18/251596 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6858 (20130101) Original (OR) Class C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011451 | Sperry |
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| FUNDED BY |
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| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert G. Sperry (Columbus, Indiana) |
| ABSTRACT | A piston can include a skirt, a crown, and a cooling gallery. The skirt can have an upper body portion. The crown can be formed at the upper body portion. A wall can be formed underneath the crown so as to define a cooling gallery within the piston. The cooling gallery includes cooling gallery peripheral portion and a cooling gallery central portion. The cooling gallery can be configured to receive and to retain an amount of cooling fluid and to cause movement thereof within the cooling gallery between a cooling gallery peripheral portion and a cooling gallery central portion as the piston travels between top dead center and bottom dead center so as to cool both the piston outer region and the piston center region. |
| FILED | Friday, December 03, 2021 |
| APPL NO | 18/265154 |
| CURRENT CPC | Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 3/22 (20130101) Original (OR) Class F02F 3/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011637 | Dai et al. |
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| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Zhongtao Dai (West Hartford, Connecticut); Peter AT Cocks (South Glastonbury, Connecticut) |
| ABSTRACT | A combustor for a rotating detonation engine includes a radially outer wall extending along an axis (A); a radially inner wall extending along the axis (A), wherein the radially inner wall is positioned within the radially outer wall to define an annular detonation chamber having an inlet for fuel and oxidant and an outlet; a first passage for feeding at least one of the fuel and the oxidant along a first passage axis (a1) to the inlet; a second passage for feeding at least one of the fuel and the oxidant along a second passage axis (a2) to the inlet, wherein the second passage axis is arranged at an angle (a) relative to the first passage axis whereby mixing of flow from the first passage and the second passage is induced. |
| FILED | Friday, June 23, 2023 |
| APPL NO | 18/213571 |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 5/00 (20130101) F02C 5/02 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 7/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011688 | Barg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Delta Development Team, Inc. (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Barg (Tucson, Arizona); Christopher Bridgewater (Tucson, Arizona); Robert Futch (Tucson, Arizona); Montgomery Leija (Sahuarita, Arizona) |
| ABSTRACT | Systems, methods, and devices may include a cooled storage system with a case having an outer bucket with a first bottom wall and a first sidewall. The outer bucket may include a flange protruding from the first sidewall. An inner bucket may be disposed at least partially within the outer bucket and may include a second bottom wall and a second sidewall defining a storage compartment in the case. A coil may be at least partially disposed in the volume between the inner bucket and the outer bucket with a phase-change material disposed about the coil. An electronic control system may actively and passively cool the storage compartment resulting in extremely efficient and precise temperature control. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 18/189130 |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 13/00 (20130101) F25B 49/02 (20130101) Original (OR) Class Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 11/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011724 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Nanfang Yu (Fort Lee, New Jersey); Norman Shi (San Jose, California); Meng Tian (Fort Lee, New Jersey) |
| ABSTRACT | Devices for radiative cooling and optical waveguiding are provided, wherein the devices comprise a fabric including one or more fibers extending for a length in a longitudinal direction and a plurality of void structures positioned within each of the one or more fibers and extended over the length of each of the one or more fibers. Each of the plurality of void structures is configured to scatter at least a portion of an electromagnetic radiation received thereon to thereby radiatively cool the object. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/327184 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/06 (20130101) D01D 1/106 (20130101) D01D 5/06 (20130101) D01D 5/16 (20130101) D01D 5/247 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/04 (20130101) D01F 1/06 (20130101) D01F 1/106 (20130101) D01F 2/00 (20130101) D01F 4/02 (20130101) D01F 6/12 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/022 (20130101) D10B 2401/22 (20130101) D10B 2403/02421 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/003 (20130101) Original (OR) Class F28F 2245/06 (20130101) Optical Elements, Systems, or Apparatus G02B 6/10 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/25 (20150115) Y10T 428/2915 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011751 | Adasczik et al. |
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| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Walter K. Adasczik (Nashua, New Hampshire); Jeffrey A. Lizotte (Dracut, Massachusetts); Peter H. Remeis (Pelham, New Hampshire); Nicholas Collard (Nashua, New Hampshire) |
| ABSTRACT | A switch assembly and a method of effecting a battery to initiate. The switch assembly includes a support that is adapted to operably engage with a battery. The switch assembly also include a slide operably engaged with the support and moveable in a first direction relative to the support between a primed position and a released position. The switch assembly also includes a cover operably engaged with the support and enclosing the slide. The switch assembly also includes a firing pin mechanism operably engaged with the support, the slide, and the cover and moveable in a second direction relative to the slide and the support. In the switch assembly, the second direction of the firing pin mechanism is different than the first direction of the slide. |
| FILED | Wednesday, July 06, 2022 |
| APPL NO | 17/858432 |
| CURRENT CPC | Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/21 (20130101) Original (OR) Class Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 3/32 (20130101) H01H 9/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011820 | ALLEN |
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| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Nathan A. ALLEN (San Antonio, Texas) |
| ABSTRACT | A jack assembly includes a body. The jack assembly also includes a lifting piston positioned at least partially above the body and configured to move up and down with respect to the body. The jack assembly also includes a lock collar positioned at least partially around the lifting piston. The lock collar is configured to move up and down with respect to the lifting piston in response to rotating the lock collar with respect to the lifting piston. The jack assembly also includes a load cell positioned at least partially around the lifting piston and between the body and the lock collar. The jack assembly is configured to support an object, which exerts a downward force onto the lifting piston. The downward force is transferred from the lifting piston to the lock collar to the load cell to the body. The load cell measures the downward force. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859434 |
| CURRENT CPC | Weighing G01G 7/00 (20130101) G01G 19/02 (20130101) G01G 21/283 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011865 | Giurgiutiu et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Victor Giurgiutiu (Columbia, South Carolina); MD Yeasin Bhuiyan (Vergennes, Vermont); Matthew Droghini (Aiken, South Carolina) |
| ABSTRACT | A new vibration test-cell that allows a static load to be applied simultaneously with lateral vibration coupled with in-situ microscopy that allows for the ability to open a fatigue crack up to a desired gap, as well as generate acoustic emission (AE) from vibration excitation, micro-fracture events are captured by the AE measurement while the physical observation of the crack faying surfaces is performed in-situ with an optical microscope embedded in the test cell. |
| FILED | Friday, June 16, 2023 |
| APPL NO | 18/336165 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 7/022 (20130101) G01M 7/025 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/32 (20130101) G01N 2203/0067 (20130101) G01N 2203/0658 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011928 | Potyrailo et al. |
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| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Janell Marie Crowder (Clifton Park, New York) |
| ABSTRACT | A system and a method for multi-gas sensing using dielectric excitation of a single sensing material operated at a single operating temperature. Contrary to conventional gas sensor designs, embodiments of the gas sensors disclosed herein implement a metal oxide semiconductor sensing material maintained at a constant temperature, wherein dielectric excitation responses of the sensing material are measured at this constant temperature while the sensing material is exposed to a fluid sample. The disclosed gas sensors and gas sensing methods unexpectedly provide desirable characteristics, such as enhanced multi-gas differentiation, while operating at the constant operating temperature. For example, by measuring dielectric excitation responses of using at least one gas sensing element at a single operating temperature, the disclosed gas sensors and gas sensing methods demonstrate superior multi-gas differentiation compared to other gas sensors and other gas sensing methods that rely on multiple resistance measurements performed at several different operating temperatures. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859874 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 27/221 (20130101) Original (OR) Class G01N 33/0027 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011934 | Potyrailo et al. |
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| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Baokai Cheng (Niskayuna, New York); Janell Marie Crowder (Clifton Park, New York) |
| ABSTRACT | An electrochemical gas sensor for multi-gas analysis of a fluid sample includes an electrochemical gas sensing element and a data collection component. The data collection component is configured to cycle the electrochemical gas sensing element between first excitation and signal detection values and second excitation and signal detection values at a predetermined time constant, and to measure responses of the electrochemical gas sensor to the fluid sample at the first excitation and signal detection values and the second excitation and signal detection values wherein the responses of the electrochemical gas sensor to the fluid sample at the first excitation and signal detection values and the second excitation and signal detection values are indicative of identities, respective concentrations, or a combination thereof, of at least two analyte gases of the fluid sample. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859921 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/404 (20130101) Original (OR) Class G01N 27/413 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011990 | SANKAR et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Karthika SANKAR (Boston, Massachusetts); Scott SCHAUS (Boston, Massachusetts); James GALAGAN (Needham, Massachusetts); Catherine KLAPPERICH (Brookline, Massachusetts); John CONNOR (Newton, Massachusetts); Mark GRINSTAFF (Brookline, Massachusetts); Keith HEARON (Boston, Massachusetts) |
| ABSTRACT | The systems, methods, devices and kits disclosed herein be used to determine the presence and/or level a target analyte(s) in a biological sample, wherein the analyte(s) is associated with a pathogenic (e.g., a viral antigen or whole virus) or otherwise altered physiological condition (e.g., pregnancy). In certain embodiments, the systems, methods, devices and kits provide one or more improved properties relative to the RT-PCT and lateral flow antibody assays known in the art for the detection of SARS-CoV-2, including but not limited to, assay time, ease of use, risk of infection, accuracy, specificity, selectivity, limit of detection of the assay, quantitative detection and the effect of common interferents to the sensor output, cost, simplicity or a combination thereof. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 18/016497 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3272 (20130101) G01N 27/3276 (20130101) G01N 27/3277 (20130101) G01N 27/3278 (20130101) G01N 33/5308 (20130101) G01N 33/54386 (20130101) G01N 33/56983 (20130101) Original (OR) Class G01N 2333/11 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012039 | Salim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ColdQuanta, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan Salim (Lafayette, Colorado); Dana Zachary Anderson (Boulder, Colorado); Jayson Denney (Golden, Colorado); Farhad Majdeteimouri (Broomfield, Colorado) |
| ABSTRACT | A microwave sensor determines an electric-field strength of a microwave field populated by quantum particles in an ultra-high vacuum (UHV) cell. A probe laser beam and a coupling laser beam are directed into the UHV cell so that they are generally orthogonal to each other and intersect to define a “Rydberg” intersection, so-called as the quantum particles within the Rydberg intersection transition to a pair of Rydberg states. The frequency of the probe laser beam is swept so that a frequency spectrum of the probe laser beam can be captured. The frequency spectrum is analyzed to determine a frequency difference between Autler-Townes peaks. The electric-field strength of the microwave field within the Rydberg intersection is then determined based on this frequency difference. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/116698 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/0885 (20130101) Original (OR) Class G01R 33/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012171 | ANDERSON et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Brian ANDERSON (Mt. Airy, Maryland); Regupathi ANGAPPAN (Baltimore, Maryland); Robin BARNES (Elkridge, Maryland); Sabine STANLEY (Finksburg, Maryland); Sarah VINES (Baltimore, Maryland) |
| ABSTRACT | A computer-implemented method includes: receipt and accession of magnetic field data from a constellation of satellites providing global coverage over the Earth in a time span less than one day; inter-calibrating the magnetic field data from all satellites to a common standard; quantifying the global magnetic disturbance and selecting quiescent intervals at least as short as one day for evaluation of Earth's internally-generated field; calculating global maps of the mean vector magnetic field for each quiet interval from the average of all satellite measurements in angular bins; converting the time sequence of global maps of the mean fields to time series of angular harmonic coefficients via direct convolution; applying spectral and regression analysis to the harmonic coefficient time series to identify and remove artifacts in the signals; reconstructing a continuous time and spatial representation of the magnetic field continuous in time and angular position globally. |
| FILED | Thursday, September 02, 2021 |
| APPL NO | 18/023911 |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/36 (20130101) G01V 3/38 (20130101) G01V 3/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012198 | Miri et al. |
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| FUNDED BY |
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| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohammad-Ali Miri (Plainview, New York); Kevin Dagoberto Zelaya Mendoza (New York, New York) |
| ABSTRACT | A device for performing unitary matrix computations comprises a light source configured to generate first optical signals; an array of waveguides, including: inputs that receive the first optical signals from the light source; a plurality of channels positioned in parallel for transmitting the first optical signals along a length of the waveguides; and outputs for outputting second optical signals generated according to a matrix multiplication operation from the first optical signals. The device further comprises phase shifters constructed and arranged in a cascade structure at the channels of the waveguides, the waveguides include sections or directional couplers between adjacent phase shifter. The matrix multiplication operation includes coupling coefficient values between adjacent waveguides and length values of the sections of the waveguides. General non-unitary matrix computations are implemented by interlacing two embodiments of the device together with an array of amplitude modulators. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/350538 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12011 (20130101) Original (OR) Class G02B 6/12016 (20130101) G02B 2006/121 (20130101) G02B 2006/12147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012201 | Withers et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Nathan Jack Withers (Albuquerque, New Mexico); Marek Osinski (Albuquerque, New Mexico) |
| ABSTRACT | A semiconductor photodetector comprising a closed loop configured to receive light from an external source adapted to trap light within said closed loop until absorption by the semiconductor. |
| FILED | Thursday, September 21, 2023 |
| APPL NO | 18/472183 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) G02B 6/243 (20130101) Original (OR) Class G02B 6/266 (20130101) G02B 6/1225 (20130101) G02B 6/12007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012400 | Tamaskar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Siemens Corporation (Washington, District of Columbia) |
| ASSIGNEE(S) | Siemens Corporation (Washington, District of Columbia) |
| INVENTOR(S) | Shashank Tamaskar (Mohali, Punjab, India); Martin Sehr (Kensington, California); Eugen Solowjow (Berkeley, California); Wei Xi Xia (Daly City, California); Juan L. Aparicio Ojea (Moraga, California); Ines Ugalde Diaz (Redwood City, California) |
| ABSTRACT | A computer-implemented method for failure classification of a surface treatment process includes receiving one or more process parameters that influence one or more failure modes of the surface treatment process and receiving sensor data pertaining to measurement of one or more process states pertaining to the surface treatment process. The method includes processing the received one or more process parameters and the sensor data by a machine learning model deployed on an edge computing device controlling the surface treatment process to generate an output indicating, in real-time, a probability of process failure via the one or more failure modes. The machine learning model is trained on a supervised learning regime based on process data and failure classification labels obtained from physics simulations of the surface treatment process in combination with historical data pertaining to the surface treatment process. |
| FILED | Friday, August 28, 2020 |
| APPL NO | 18/041718 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/41875 (20130101) Original (OR) Class G05B 2219/32193 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012728 | Nieh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jason Nieh (New York, New York); Ronghui Gu (New York, New York); Xuheng Li (New York, New York); Xupeng Li (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Nieh (New York, New York); Ronghui Gu (New York, New York); Xuheng Li (New York, New York); Xupeng Li (New York, New York) |
| ABSTRACT | Mechanisms for verifying software on a multi-CPU machine are provided, the mechanisms including: using a hardware processor: reordering, in a shared log, a first local CPU event from a local CPU operating on a shared object to be before at least one first prior oracle query corresponding to a prior event from another CPU based on whether the first local CPU event can be reordered with respect to the prior event without changing the multi-CPU machine's behavior with respect to the shared object; merging first consecutive oracle queries including the at least one first prior oracle query in the shared log; and verifying the software based on the merged first consecutive oracle queries. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/220229 |
| CURRENT CPC | Electric Digital Data Processing G06F 11/28 (20130101) Original (OR) Class G06F 11/3612 (20130101) G06F 11/3636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012954 | Greunke |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Larry Clay Greunke (Seaside, California) |
| ABSTRACT | This disclosure and exemplary embodiments described herein provide methods and systems for a blockchain-based system for managing discrepancies, assigning procedures, ensuring quality assurance, and updating digital twins with real-world information. According to an embodiment, the system uses a combination of smart contracts and a decentralized network to facilitate transparency, security, and efficiency in various industries such as manufacturing, construction, and maintenance. The system includes multiple block types, each representing a specific aspect of the process: marking up discrepancies, assigning Parallel Content Authored instructions, completing tasks with quantitative quality assurance, and updating digital twins. By leveraging the inherent advantages of blockchain technology, this system provides an auditable, tamper-proof record of the entire process while streamlining interactions between different blocks. |
| FILED | Tuesday, May 30, 2023 |
| APPL NO | 18/203482 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/12 (20200101) Original (OR) Class Image Data Processing or Generation, in General G06T 19/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013077 | Inoue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ken Inoue (Elmsford, New York); Maika Takita (Croton-on-Hudson, New York); Antonio Corcoles-Gonzalez (Mount Kisco, New York); Scott Douglas Lekuch (New York, New York) |
| ABSTRACT | Systems, computer-implemented methods, and computer program products that can facilitate determining a state of a qubit are described. According to an embodiment, a system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can comprise an output receiving component that can receive, in response to a request, output representative of a quantum state of a qubit of a quantum computing device, and a classifying component that classifies the quantum state of the qubit of the quantum computing device based on the output representative of the quantum state of the qubit. The system can further include a configuring component that can configure the classifying component based on a characteristic of the request. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183602 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) G06F 18/2411 (20230101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class G06N 10/20 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013418 | Kozub et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Megan M. Kozub (King George, Virginia); Brandon K. Marine (Fredericksburg, Virginia); Tyler J. Ferro (King George, Virginia); Nicholas A. Sievert, III (Henrico, Virginia); Christopher R. Cheatham (Fredericksburg, Virginia); William E. Friend (Mechanicsville, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Megan M. Kozub (King George, Virginia); Brandon K. Marine (Fredericksburg, Virginia); Tyler J. Ferro (King George, Virginia); Nicholas A. Sievert, III (Henrico, Virginia); Christopher R. Cheatham (Fredericksburg, Virginia); William E. Friend (Mechanicsville, Virginia) |
| ABSTRACT | A measurement system is provided for assessing dimensions of a human body. The system includes a stereoscopic camera, and an autonomous processor. The camera captures the body standing from front and side perspectives. The processor identifies reference points corresponding to extremity locations and joints on the body. The processor further calculates distances between the reference points and determining the dimensions for output and subsequently estimates a pose envelope from the distances. The processor then compares the pose envelope to confinement restraints for predicting anthropometric conformity to the restraints. A computer-implemented method performing operations by the processor is also provided. |
| FILED | Thursday, April 27, 2023 |
| APPL NO | 18/140380 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/60 (20130101) Original (OR) Class G06T 7/74 (20170101) G06T 2207/10012 (20130101) G06T 2207/30196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013662 | Trent et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Architecture Technology Corporation (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barry A. Trent (Chanhassen, Minnesota); Ranga S. Ramanujan (Medina, Minnesota); Fabio F. Pozzo (Minneapolis, Minnesota); Ian McLinden (Eden Prairie, Minnesota); Jordan C. Bonney (Bloomington, Minnesota) |
| ABSTRACT | A method of generating a plan for a vehicle is provided. The method includes receiving information indicating a location of each of a plurality of communication nodes and the vehicle during a first time period and a second time period. The vehicle is configured to send wireless signals to and receive wireless signals with the plurality of communication nodes. The method includes developing a plan that defines a path of motion for the vehicle and a configuration for an antenna on the vehicle during the first time period and the second time period based on connectivity between the vehicle and the plurality of communication nodes. |
| FILED | Monday, February 20, 2023 |
| APPL NO | 18/171434 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/20 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0022 (20130101) G05D 1/104 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/047 (20130101) Traffic Control Systems G08G 5/0013 (20130101) G08G 5/0026 (20130101) G08G 5/0034 (20130101) Original (OR) Class G08G 5/0039 (20130101) G08G 5/0043 (20130101) G08G 5/0086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014071 | Banerjee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kaustav Banerjee (Goleta, California); Junkai Jiang (Sunnyvale, California); Kunjesh Agashiwala (Santa Barbara, California) |
| ABSTRACT | An MLG (multilayer graphene) device layer structure is connected with a via. The structure includes an M1 MLG interconnect device layer upon a dielectric layer. Interlayer dielectric isolates the M1 MLG interconnect device layer. An M2 MLG interconnect device layer is upon the interlayer dielectric. A metal via penetrates through the M2 MLG interconnect device layer, the interlayer dielectric and the M1 MLG interconnect device layer and makes edge contact throughout the thickness of both M1 MLG and M2 MLG layers. A method diffuses carbon from a solid phase graphene precursor through a catalyst layer to deposit MLG on a dielectric or metal layer via application of mechanical pressure at a diffusion temperature to form MLG layers. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 18/252459 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/76802 (20130101) H01L 21/76871 (20130101) H01L 21/76877 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014263 | Feigelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Boris N. Feigelson (Springfield, Virginia); Alexander L. Efros (Annandale, Virginia); Benjamin L. Greenberg (Alexandria, Virginia); Michael Shur (Vienna, Virginia) |
| ABSTRACT | A bipolar nanocomposite semiconductor (BNS) material in which electrons and holes are separately transported throughout the BNS volume via an interpenetrating plurality of networks, where some of the networks have one conductivity type and others have the opposite conductivity type. The interpenetrating networks can include one or more multiple nanocrystalline structures, metal and dielectric networks and are intimately connected to enable band-like transport of both electrons and holes throughout the material. |
| FILED | Friday, September 23, 2022 |
| APPL NO | 17/951181 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0619 (20130101) H01L 29/0665 (20130101) Original (OR) Class H01L 29/732 (20130101) H01L 29/7311 (20130101) H01L 29/66242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014271 | Feigelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Boris N. Feigelson (Springfield, Virginia); Alexander L. Efros (Annandale, Virginia); Benjamin L. Greenberg (Alexandria, Virginia); Michael Shur (Vienna, Virginia) |
| ABSTRACT | A bipolar nanocomposite semiconductor (BNS) material in which electrons and holes are separately transported throughout the BNS volume via an interpenetrating plurality of networks, where some of the networks have one conductivity type and others have the opposite conductivity type. The interpenetrating networks can include one or more multiple nanocrystalline structures, metal and dielectric networks and are intimately connected to enable band-like transport of both electrons and holes throughout the material. |
| FILED | Friday, September 23, 2022 |
| APPL NO | 17/951168 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/151 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014285 | Rajan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siddharth Rajan (Columbus, Ohio); Sushovan Dhara (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are semiconductor devices with a compositionally graded layer, and methods of making and use thereof. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/143191 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) H01L 29/45 (20130101) H01L 29/47 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014337 | KOTOV et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas KOTOV (Ann Arbor, Michigan); Drew VECCHIO (Ann Arbor, Michigan); Brandon DAVIS (Ann Arbor, Michigan); Mark HAMMIG (Dexter, Michigan) |
| ABSTRACT | A device for radiation detection includes a first electrode, a second electrode spaced apart from the first electrode, and a macroscale structure disposed between the first electrode and the second electrode. The macroscale structure comprises a composite arrangement of nanocrystalline particles. The nanocrystalline particles comprise a lead chalcogenide material. The nanocrystalline particles establish conductive paths between the first electrode and the second electrode without an intervening conductive polymer agent. |
| FILED | Wednesday, July 05, 2023 |
| APPL NO | 18/218360 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/241 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/085 (20130101) H01L 31/0324 (20130101) H01L 31/0384 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014454 | BLOOMSTEIN |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Theodore BLOOMSTEIN (Medford, Massachusetts) |
| ABSTRACT | A battery array comprising a plurality of batteries. Each battery comprises a plurality of stacked battery cells, wherein the battery cells have varying properties. Each battery cell comprises an anode layer; a cathode layer; an ion conducting membrane positioned between the anode layer and the cathode layer; a top layer; a bottom layer; and circuitry disposed on the top layer, bottom layer, or both. The circuitry comprising one or more first circuits for monitoring or controlling the battery cell. Further, the battery comprises a battery control circuit configured to provide electrical interface connections with the circuitry. The battery array comprises a battery array control circuit configured to provide electrical interface connections with the battery control circuits of each battery. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183548 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/46 (20130101) H01M 10/425 (20130101) Original (OR) Class H01M 10/482 (20130101) H01M 10/486 (20130101) H01M 50/242 (20210101) H01M 50/509 (20210101) H01M 50/533 (20210101) H01M 50/569 (20210101) H01M 2010/4271 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0029 (20130101) H02J 7/0047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014631 | Poulton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Analog Photonics LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Analog Photonics LLC (Boston, Massachusetts) |
| INVENTOR(S) | Christopher Vincent Poulton (Somerville, Massachusetts); Matthew Byrd (Arlington, Massachusetts); Peter Nicholas Russo (Arlington, Massachusetts); Diedrik Vermeulen (Boston, Massachusetts) |
| ABSTRACT | An apparatus comprises an optical cavity formed on a substrate and defining a round-trip optical path, an interface positioning at least a portion of a gain medium to provide an active portion of the round-trip optical path over which the gain medium provides sufficient gain for the optical wave to propagate around the round-trip optical path in a single mode, an output coupler coupling a portion of the optical wave out of the optical cavity from a passive portion of the round-trip optical path into a waveguide segment formed on the substrate, one or more tap couplers each diverting less than 50% of optical power from the waveguide segment, and one or more on-chip modules each receiving diverted optical power from at least one of the tap couplers and providing information associated with a laser that comprises the optical cavity and the gain medium. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/347907 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/021 (20130101) H01S 5/0225 (20210101) H01S 5/0687 (20130101) Original (OR) Class H01S 5/06817 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240015062 | DAMODARAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Suresh K. DAMODARAN (Burlington, Massachusetts); Jesus N. ABELARDE, JR. (Stow, Massachusetts); Benjamin Robert SCHMIDT (Acton, Massachusetts); Peter MALINOVSKY (Arlington, Massachusetts); Bryan Lewis QUINN (Amesbury, Massachusetts) |
| ABSTRACT | Disclosed herein are systems and methods for reducing or mitigation alert fatigue from real-time alerts in cyber-physical systems or other types of edge computing systems are provided. In one or more examples, the edge computing system monitor can look for one or more patterns within received data that can indicate malicious activity or other conditions that may warrant a real-time or near-real time response from the operator. In one or more examples, a detection of any of the specified patterns in the streaming data can trigger an alert to the operator of the edge computing system. In one or more examples, the alerts can be suppressed until the number of alerts associated with a particular pattern crosses a pre-determined threshold. Additionally or alternatively, alerts can be suppressed based on a duration that the alerts have been generated. The suppression of alerts can be configured to reduce operator alert fatigue. |
| FILED | Monday, July 11, 2022 |
| APPL NO | 17/862193 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/16 (20130101) H04L 41/0604 (20130101) Original (OR) Class H04L 41/0893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240015169 | DAMODARAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Suresh K. DAMODARAN (Burlington, Massachusetts); Jesus N. ABELARDE, JR. (Stow, Massachusetts); Benjamin Robert SCHMIDT (Acton, Massachusetts) |
| ABSTRACT | Accordingly, systems and methods for facilitating operator assisted responses to real-time alerts in cyber-physical systems or other types of edge computing systems are provided. In one or more examples, an edge computing system of an enterprise computing network (where an operator is stationed to operate it), can comprise an edge computing system monitor. In one or more examples, the edge computing system monitor can receive streaming analytic data from one or more components of the edge computing system. In one or more examples, the edge computing system monitor can look for one or more patterns within the received data that can be indicative of malicious activity or other conditions that may warrant a real-time or near-real time response from the operator. In one or more examples, a detection of any of the specified patterns in the streaming data can trigger an alert to the operator of the edge computing system. |
| FILED | Monday, July 11, 2022 |
| APPL NO | 17/862190 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) Original (OR) Class H04L 63/1425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240008875 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LIVERMORE, California); THE TEXAS A and M UNIVERSITY SYSTEM (COLLEGE STATION, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas S. Wilson (San Leandro, California); Ward Small, IV (Livermore, California); William J. Benett (Livermore, California); Jason M. Ortega (Pacifica, California); Duncan J. Maitland (College Station, Texas); Jonathan Hartman (Sacramento, California) |
| ABSTRACT | An embodiment of the invention includes an expandable implant to endovascularly embolize an anatomical void or malformation, such as an aneurysm. An embodiment is comprised of a chain or linked sequence of expandable polymer foam elements. Another embodiment includes an elongated length of expandable polymer foam coupled to a backbone. Another embodiment includes a system for endovascular delivery of an expandable implant (e.g., shape memory polymer) to embolize an aneurysm. The system may include a microcatheter, a lumen-reducing collar coupled to the distal tip of the microcatheter, a flexible pushing element detachably coupled to an expandable implant, and a flexible tubular sheath inside of which the compressed implant and pushing element are pre-loaded. Other embodiments are described herein. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/469671 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/06 (20130101) Original (OR) Class A61F 2310/00071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009645 | SARNIK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sylvia SARNIK (Lakewood, Colorado); Simon James Bradshaw MALLINSON (Lakewood, Colorado); Peter SMITH (Arvada, Colorado); Yannick J. BOMBLE (Arvada, Colorado); Hunter Blake HARRINGTON (Lakewood, Colorado) |
| ABSTRACT | Disclosed herein are methods and compositions for a new way to separate biologics using coated pegboards—plastic plates affixed with an array of 96-pegs which align with the wells of a traditional 96-well plate used in bench top experiments. The ends of the pegs are conjugated to various compounds which are able to bind tags on engineered proteins (ex. Ni-NTA would bind a His-Tag on an engineered protein). These pegs extend into plate wells to specifically bind the tagged protein from the cell lysate which contains hundreds of other proteins. The pegboard, now laden with the protein of interest (POI), may then be dipped into sequential buffers to wash away potential non-specifically bound proteins to purify the POI. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/349867 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00623 (20130101) B01J 2219/00668 (20130101) B01J 2219/00725 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009648 | Hicks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Christopher Hicks (South Bend, Indiana); Deanna Poirier (South Bend, Indiana); Gerardo Rivera-Castro (South Bend, Indiana) |
| ABSTRACT | Shale processing systems may include a reactor comprising. a first inlet in fluid communication with a shale gas source. a plasma zone in fluid communication with the first inlet, the plasma zone comprising, an outlet in fluid communication with the plasma zone, a collection vessel configured to receive fluid from the reactor outlet, and a voltage supply and monitor system in electrical communication with the inner electrode and with the outer electrode. The shale gas processing systems may be configured to generate various fluid products, including nitrogen (N)-containing compounds. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345866 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 21/0605 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/04 (20130101) Acyclic or Carbocyclic Compounds C07C 2/76 (20130101) C07C 209/02 (20130101) C07C 253/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009725 | Taysom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brandon Scott Taysom (West Richland, Washington); MD. Reza-E-Rabby (Richland, Washington); Scott A. Whalen (West Richland, Washington) |
| ABSTRACT | Shear assisted extrusion apparatus, tools, inserts, and/or methods are provided. The apparatuses can include: an extrusion receiving channel operably engaged with a tool to receive extruded material; and one or more openings aligned between the spindle ends, the openings configured to convey fluid to the extruded product. Example tools can include one or more openings aligned between the tool ends. Example methods can include quenching plasticized feed material before exiting the spindle. A spindle assembly and/or tool assembly inserts are also provided that can include a sleeve extending within one or both of the spindle assembly or tool assembly of the apparatus; and openings within the sleeve configured to convey fluid to within one or both of the receiving channel of the spindle assembly or the tool assembly. |
| FILED | Tuesday, July 05, 2022 |
| APPL NO | 17/857951 |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 23/001 (20130101) B21C 23/085 (20130101) B21C 25/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010183 | Le et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dat Duc Le (Columbus, Indiana); Carlos A. Lana (Columbus, Indiana); Kenneth M. Follen (Greenwood, Indiana) |
| ABSTRACT | A system and method for power management of hybrid electric vehicles is provided. In some implementations, a plug-in series hybrid electric vehicle may include an engine, a motor/generator (MG), a traction motor, an energy storage device, and a controller. The controller is coupled to the engine and the MG to control operation of the engine and the MG such that a state-of-charge (SOC) of the energy storage device tracks a dynamic reference SOC profile during a trip and an average engine power (AEP) is maintained above a threshold. In some instances, maintaining AEP above a threshold supports emission control of the vehicle. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/370546 |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 6/24 (20130101) B60K 6/26 (20130101) B60K 6/28 (20130101) B60K 6/46 (20130101) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/06 (20130101) B60W 10/08 (20130101) B60W 20/11 (20160101) B60W 20/12 (20160101) B60W 20/13 (20160101) Original (OR) Class B60W 2510/068 (20130101) B60W 2510/244 (20130101) B60W 2510/0619 (20130101) B60W 2510/0666 (20130101) B60W 2510/0676 (20130101) B60W 2520/10 (20130101) B60W 2530/209 (20200201) B60W 2540/10 (20130101) B60W 2555/20 (20200201) B60W 2710/06 (20130101) B60W 2710/08 (20130101) Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology B60Y 2200/92 (20130101) B60Y 2300/91 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010582 | HICKS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Christopher HICKS (South Bend, Indiana); Gerardo RIVERA-CASTRO (South Bend, Indiana) |
| ABSTRACT | Exemplary systems and methods process gas streams comprising methane. Exemplary reactors receive a gas stream and comprise catalyst material in a reaction zone. Non-thermal plasma may be generated in the reaction zone. A temperature of the reaction zone may be maintained within a predetermined temperature range. Products may be collected from a reactor outlet. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345908 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/0278 (20130101) B01J 8/0285 (20130101) B01J 29/48 (20130101) B01J 2208/00805 (20130101) B01J 2208/00973 (20130101) Acyclic or Carbocyclic Compounds C07C 2/80 (20130101) Original (OR) Class C07C 2529/076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011056 | Jin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Yong-Su Jin (Champaign, Illinois); Jae Won Lee (Champaign, Illinois); Young B. Cho (Savoy, Illinois); Ye-Gi Lee (Savoy, Illinois) |
| ABSTRACT | Provided herein are compositions and methods for the fermentative production of 2,3-butanediol (2,3-BDO), compositions and methods for making methyl ethyl ketone (MEK), and methods of inducing drought tolerance in plants. |
| FILED | Wednesday, July 05, 2023 |
| APPL NO | 18/347473 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/32 (20200101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 21/00 (20210801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/16 (20130101) C12N 9/88 (20130101) C12N 9/1205 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) Original (OR) Class Enzymes C12Y 101/01001 (20130101) C12Y 101/01009 (20130101) C12Y 101/01037 (20130101) C12Y 207/01017 (20130101) C12Y 401/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011077 | Schulman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rebecca B. Schulman (Baltimore, Maryland); Daniel Siegal (Baltimore, Maryland); Yi Li (Baltimore, Maryland); Samuel Schaffter (Baltimore, Maryland); Joanna Schneider (Baltimore, Maryland) |
| ABSTRACT | Described are systems comprising nucleic acid nanostructures, e.g., nanotubes, for use in detecting biological agents. The systems comprise a nucleic acid nanotube, nucleic acid nanotube seed, a plurality nucleic acid nanotube monomers, or a combination there of; a nucleic acid nanotube terminus; and an activation strand comprising a single-stranded nucleic acid comprising a first sequence complementary to a portion of the nucleic acid nanotube, nucleic acid nanotube seed, nucleic acid nanotube monomers and a second sequence complementary to a portion of the nucleic acid nanotube terminus. Devices, kits, and methods comprising the systems are also described. |
| FILED | Monday, October 04, 2021 |
| APPL NO | 18/247794 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011195 | Bidhar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sujit Bidhar (Carol Stream, Illinois) |
| ABSTRACT | An electrospinning system, method, and apparatus comprises a dual polarity high voltage power supply with much less power out for safe operation, a solution dispensing assembly held at high positive potential by the dual polarity power supply, a Corona discharge assembly held at high negative potential by the dual polarity power supply, and a drum collector held at ground potential wherein a solution is drawn from the solution dispensing assembly to the drum collector thereby forming a fiber mat. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/370777 |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/06 (20130101) D01D 5/0061 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2321/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011353 | ZHANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaosheng ZHANG (Berkeley, California); Ming Chiang A. WU (Moraga, California); Andrew S. MICHAELS (Berkeley, California); Johannes HENRIKSSON (Berkeley, California) |
| ABSTRACT | An integrated-optics MEMS-actuated beam-steering system is disclosed, wherein the beam-steering system includes a lens and a programmable vertical coupler array having a switching network and an array of vertical couplers, where the switching network can energize of the vertical couplers such that it efficiently emits the light into free-space. The lens collimates the light received from the energized vertical coupler and directs the output beam along a propagation direction determined by the position of the energized vertical coupler within the vertical-coupler array. In some embodiments, the vertical coupler is configured to correct an aberration of the lens. In some embodiments, more than one vertical coupler can be energized to enable steering of multiple output beams. In some embodiments, the switching network is non-blocking. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/370600 |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/34 (20130101) E06B 9/42 (20130101) E06B 9/80 (20130101) Original (OR) Class E06B 9/325 (20130101) E06B 9/326 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/292 (20130101) G02F 1/3132 (20130101) G02F 1/3137 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011674 | Munk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey D. Munk (Oak Ridge, Tennessee); Bo Shen (Oak Ridge, Tennessee); Kyle R. Gluesenkamp (Oak Ridge, Tennessee) |
| ABSTRACT | An improved heat pump including an integrated system for the management of refrigerant charge is provided. The integrated system actively adjusts charge allocation and thereby optimizes operational efficiencies in all modes of operation. In one embodiment, the integrated system includes three four-way valves, two expansion valves, two one-way check valves, and a suction line accumulator to optimize charge allocation. The four-way valves dictate the mode switch and refrigerant flow directions, and the expansion valves automatically allocate refrigerant mass in active components and store excess charge in an idle heat exchanger and suction line accumulator by controlling the compressor discharge pressure (equivalent to controlling condenser subcooling degree) as a function of the entering air and water temperatures. The integrated system provides seven working modes and is uniquely suited for spacing cooling, spacing heating, and water heating in both residential and commercial applications. |
| FILED | Thursday, June 29, 2023 |
| APPL NO | 18/216060 |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 13/00 (20130101) Original (OR) Class F25B 2313/02743 (20130101) F25B 2400/19 (20130101) F25B 2400/0411 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011859 | Sweeney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel C. Sweeney (Oak Ridge, Tennessee); Anthony Birri (Oak Ridge, Tennessee); Christian M. Petrie (Oak Ridge, Tennessee) |
| ABSTRACT | A system and method for monitoring Fabry-Perot cavity (“FPC”) displacement implementing a predictor-corrector scheme. The system includes an optical interrogator apparatus and a data processing apparatus. The optical interrogator apparatus interrogates the FPC, obtains a spectral interference pattern and outputs a corresponding signal including data associated with a plurality of peaks. The data processing apparatus processes the output signal to produce a prediction for a peak location based on the data associated with the plurality of peaks, and then uses the prediction to identify as correct one of the plurality of peaks. The data processing apparatus then determines and outputs a plurality of FPC length variations. In one embodiment, the data processing system implements a period tracking algorithm to produce the prediction based on the data associated with the plurality of peaks, and uses a phase tracking algorithm to determine an FPC length variation using the identified peak. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/219746 |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/0079 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 17/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011885 | Hirsch |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gregory Hirsch (Pacifica, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory Hirsch (Pacifica, California) |
| ABSTRACT | A screening tool and method for screening cryogenic electron microscopy (cryo-EM) sample grids using vacuum ultraviolet (VUV) illumination in two configurations is described. First configuration directly images cryo-EM grids using essentially bright-field optical microscopy, but employing VUV wavelengths and specialized VUV optics. Second configuration converts transmitted VUV radiation from the cryo-EM grid to visible or near-UV light with a scintillator positioned in very close proximity to the grid. The resultant luminescent high-resolution shadow image is viewed using more conventional microscope optics. In both configurations, imaging of individual micron-scale grid holes is possible to determine ice thickness and quality from the optical absorption of ultrathin vitrified water layers with a precision of a few nanometers. Longer wavelengths can be used to independently view protein concentration and distribution within the ice layer. This screening tool greatly increases yield of high-quality grids before cryo-EM analysis and is compatible with Single Particle Analysis (SPA) and other cryo-EM methods including cryo-electron Tomography (cryo-ET) and microcrystal electron diffraction (MicroED). |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/114103 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/06 (20130101) Original (OR) Class G01N 2015/0693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011945 | Remillieux et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chevron U.S.A. Inc. (San Ramon, California); Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marcel Remillieux (Los Alamos, New Mexico); James A. Ten Cate (Los Alamos, New Mexico); Marcie Alberta Stuber Geesey (Los Alamos, New Mexico); Luke Berny Beardslee (Los Alamos, New Mexico); Rodney F. Deschamps (San Ramon, California); Robert Kwan Meng Seah (San Ramon, California) |
| ABSTRACT | A system for detecting cracks in an underwater structure can include an acoustic signal transmitter configured to be disposed proximate to, but without physically contacting, the underwater structure, where the acoustic signal transmitter is configured to emit acoustic signals. The system can also include an acoustic field receiver configured to be disposed proximate to, but without physically contacting, the underwater structure, where the acoustic field receiver is configured to receive resulting acoustic fields. The system can further include a controller that is configured to receive the resulting acoustic fields from the acoustic field receiver. The controller can also be configured to analyze the resulting acoustic fields signal. The controller can further be configured to detect, based on analyzing the resulting acoustic fields, a crack in the underwater structure. |
| FILED | Tuesday, August 18, 2020 |
| APPL NO | 18/041789 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/041 (20130101) Original (OR) Class G01N 29/225 (20130101) G01N 29/265 (20130101) G01N 29/346 (20130101) G01N 29/348 (20130101) G01N 2291/105 (20130101) G01N 2291/2636 (20130101) G01N 2291/2675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013054 | Martinez |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carianne Martinez (Albuquerque, New Mexico) |
| ABSTRACT | Neural network prediction correction is provided. The method comprises training a neural network with time series training data from a first domain over a number of training iterations, wherein a random subset of nodes in the neural network is dropped out during each training iteration. The trained neural network generates a number of predictions based on time series data from a second domain, wherein a random subset of nodes in the neural network is dropped out for each prediction to generate a prediction distribution. An uncertainty value is calculated for each prediction. Responsive to determination that the uncertainty value for a prediction exceeds a specified threshold, the prediction is updated to incorporate a corrective factor according to expectations based on domain knowledge. |
| FILED | Thursday, June 29, 2023 |
| APPL NO | 18/216194 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/084 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013078 | NIROULA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IONQ, INC. (College Park, Maryland); University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pradeep NIROULA (College Park, Maryland); Yunseong NAM (North Bethesda, Maryland) |
| ABSTRACT | A method of determining a pattern in a sequence of bits using a quantum computing system includes setting a first register of a quantum processor in a superposition of a plurality of string index states, encoding a bit string in a second register of the quantum processor, encoding a bit pattern in a third register of the quantum processor, circularly shifting qubits of the second register conditioned on the first register, amplifying an amplitude of a state combined with the first register in which the circularly shifted qubits of the second register matches qubits of the third register, measuring an amplitude of the first register and determining a string index state of the plurality of string index states associated with the amplified state, and outputting, by use of a classical computer, a string index associated with the first register in the measured state. |
| FILED | Monday, September 18, 2023 |
| APPL NO | 18/369327 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30032 (20130101) G06F 9/30101 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013084 | GOLTER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia); National Technology and Engineering Solution of Sandia, LLC (Albuquerque, New Mexico); MIT - Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia); National Technology and Engineering Solution of Sandia, LLC (Albuquerque, New Mexico); MIT - Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Andrew GOLTER (McLean, Virginia); Genevieve CLARK (McLean, Virginia); Tareq EL DANDACHI (McLean, Virginia); Stefan KRASTANOV (McLean, Virginia); Matthew ZIMMERMANN (McLean, Virginia); Andrew GREENSPON (McLean, Virginia); Noel WAN (McLean, Virginia); Hamza RANIWALA (McLean, Virginia); Kevin CHEN (McLean, Virginia); Linsen LI (McLean, Virginia); Andrew LEENHEER (McLean, Virginia); Mark DONG (McLean, Virginia); Gerald GILBERT (McLean, Virginia); Matthew EICHENFIELD (McLean, Virginia); Dirk ENGLUND (McLean, Virginia) |
| ABSTRACT | A scalable point defect qubit control system may include a diamond waveguide array comprising one or more diamond waveguides and a microwave line disposed proximally to the diamond waveguide array. Each diamond waveguide in the diamond waveguide array may include one or more qubits encoded in point defect sites. The microwave line may be configured to receive a direct current (DC) signal configured to shift an energy level of each point defect qubit of the one or more point defect qubits based on a position of the point defect in the diamond waveguide array, and receive an alternating current (AC) signal configured to control a quantum state of a point defect qubit of the one or more point defect qubits, wherein one or more properties of the AC signal are based on the shift in the energy level induced by the DC signal. |
| FILED | Wednesday, April 26, 2023 |
| APPL NO | 18/139684 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013472 | Clark et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Richard Trevor Clark (West Richland, Washington); David M. Sheen (Richland, Washington) |
| ABSTRACT | Surface determination systems, threat detection systems and medical treatment systems are described. According to one aspect, a surface determination system includes processing circuitry configured to access a three-dimensional complex-valued image volume of a target, define image locations of the image volume using first and second dimensions of the image volume, for each of the first locations, identify voxels along a third dimension of the image volume that correspond to the respective first location, for each of the first locations, select one voxel that corresponds to the first location as having an increased amplitude compared with other voxels that correspond to the first location, and for each selected voxel, use phase information to identify a second location in the third dimension for the selected voxel that corresponds to a location of a surface of the target and that is different than a third location of the respective voxel. |
| FILED | Thursday, April 08, 2021 |
| APPL NO | 18/019631 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/403 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/887 (20130101) G01S 13/9064 (20190501) Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 7/74 (20170101) G06T 15/08 (20130101) Original (OR) Class G06T 2207/10028 (20130101) G06T 2207/10044 (20130101) G06T 2207/30088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013852 | GANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Oleg GANG (Setauket, New York); Brian MINEVICH (New York, New York); Hamed EMAMY (New York, New York); Shuting XIANG (New York, New York); Jason S. KAHN (New York, New York); Aaron MICHELSON (New York, New York); Kim KISSLINGER (New York, New York); Sanat KUMAR (New York, New York) |
| ABSTRACT | The disclosed matter provides systems and methods for encoding an assembly of three-dimensional (3D) hierarchically ordered nanoparticle architectures through chromatic bonds. Through identification of the repeating mesovoxels including chromatic bonds and voxels, the presented disclose matter can allow for encoding the 3D architectures by using symmetries of mesovoxel, enable a compression of the information amount required for encoding. |
| FILED | Monday, July 03, 2023 |
| APPL NO | 18/217812 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/201 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/10 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013934 | Thomas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | XCIMER ENERGY, INC. (Redwood City, California); University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cliff Avery Thomas (Pittsford, New York); Conner Daniel Galloway (Foster City, California) |
| ABSTRACT | An inertial confinement fusion (ICF) system includes a target that is imploded by a driver having at least one laser source. The target includes a fusion fuel layer, an ablator layer, and a corona-forming layer. At least one laser source is configured to illuminate the target with two substantially opposed beams in two or more stages. Such illumination results in ignition of the fusion fuel layer. Other embodiments are described and claimed. |
| FILED | Wednesday, July 05, 2023 |
| APPL NO | 18/218512 |
| CURRENT CPC | Fusion Reactors G21B 1/19 (20130101) G21B 1/23 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013975 | Baker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sarah Baker (Dublin, California); Joshua Kuntz (Livermore, California); Scott K. Mccall (Livermore, California); Christine A. Orme (Oakland, California); Alexander A. Baker (Pleasanton, California); Jonathan R. I. Lee (Livermore, California) |
| ABSTRACT | A magnet includes a three-dimensional structure with nanoscale features, where the three-dimensional structure has a near net shape corresponding to a predefined shape. |
| FILED | Thursday, June 15, 2023 |
| APPL NO | 18/210567 |
| CURRENT CPC | Alloys C22C 19/07 (20130101) C22C 2202/02 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0551 (20130101) H01F 1/0556 (20130101) H01F 1/0576 (20130101) H01F 41/0266 (20130101) Original (OR) Class Dynamo-electric Machines H02K 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013992 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EATON INTELLIGENT POWER LIMITED (Dublin 4, Ireland) |
| ASSIGNEE(S) | EATON INTELLIGENT POWER LIMITED (DUBLIN 4, Ireland) |
| INVENTOR(S) | Steven Z. Chen (Coraopolis, Pennsylvania); Andrew L. Gottschalk (Monaca, Pennsylvania); Steven Schmalz (Franklin, Wisconsin); Andy Schroedermeier (Whitefish Bay, Wisconsin); Hongbin Wang (Novi, Michigan) |
| ABSTRACT | For a hybrid circuit interrupter that includes a secondary actuator disposed in series with a primary actuator, with the primary actuator used for opening the switch at ultra-fast speeds and the secondary actuator used for opening the switch at normal speeds, a performance monitoring system is disclosed. The monitoring system can use either an optical sensor or position sensitive device (PSD) to detect movement of the primary actuator. The optical sensor is coupled to the circuit interrupter housing, and a distance detection means is disposed within the secondary actuator in a manner that enables the optical sensor to detect the movement of a reference surface on the moving assembly of the primary actuator. The PSD is positioned to face a thru-hole formed in a drive shaft of the circuit interrupter, and to sense a change in position of light emitted through the thru-hole during an opening stroke. |
| FILED | Wednesday, July 06, 2022 |
| APPL NO | 17/858559 |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 33/42 (20130101) H01H 33/59 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014024 | Ibrahim |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Yehia M. Ibrahim (Richland, Washington) |
| ABSTRACT | Curved ion manipulation devices can provide relatively greater ion pathway lengths over conventional devices. Ions can be directed through one or more pairs of opposing curved surfaces of a curved ion manipulation structure. Each pair of opposing curved surfaces can be spaced apart radially relative to a common longitudinal axis of the ion manipulation structure to define a radial gap. Each pair of opposing curved surfaces can include a first electrode arrangement and a second electrode arrangement opposed to the first electrode arrangement. The first and second electrode arrangements can define an ion pathway and are configured to direct ions along the ion pathway and circumferentially through the radial gaps of the ion manipulation structure. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/861076 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/063 (20130101) Original (OR) Class H01J 49/068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014285 | Rajan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siddharth Rajan (Columbus, Ohio); Sushovan Dhara (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are semiconductor devices with a compositionally graded layer, and methods of making and use thereof. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/143191 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/24 (20130101) H01L 29/45 (20130101) H01L 29/47 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240015881 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Waltham, Massachusetts); Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Yongduk Lee (Vernon, Connecticut); Parag M. Kshirsagar (South Windsor, Connecticut); Ankit Gupta (Willimantic, Connecticut) |
| ABSTRACT | A printed circuit board (PCB) assembly includes a first PCB including at least one heat generating component. A second PCB is mounted to the first PCB. The second PCB defines a cooling path therein extending in a coolant flow direction from an inlet end of the cooling path to an outlet end of the cooling path. A plurality of power pillars extend from the first PCB and across the cooling path. |
| FILED | Monday, July 11, 2022 |
| APPL NO | 17/861584 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/144 (20130101) H05K 1/0209 (20130101) Original (OR) Class H05K 2201/042 (20130101) H05K 2201/064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240015886 | Hatch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen McGarry Hatch (Kansas City, Missouri); Jonathan Douglas Hatch (Kansas City, Missouri) |
| ABSTRACT | A conductive trace interconnect tape for use with a printed circuit board or a flexible circuit substrate comprises a top insulating layer, an electrically conductive layer, and a bottom insulating layer. The top insulating layer is formed from electrically insulating material and is configured to provide electrical isolation from electrically conductive objects that are positioned on top of the conductive trace interconnect tape. The electrically conductive layer is positioned underneath the top insulating layer. The electrically conductive layer is formed from electrically conductive material and includes electrical interconnect traces, electrical component pads, or electrically conductive planar portions. The bottom insulating layer is positioned underneath the electrically conductive layer. The bottom insulating layer is formed from electrically insulating material and is configured to provide electrical isolation from electrically conductive objects that are positioned on the printed circuit board or flexible circuit substrate. |
| FILED | Friday, September 22, 2023 |
| APPL NO | 18/472382 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/141 (20130101) H05K 1/0292 (20130101) H05K 3/225 (20130101) Original (OR) Class H05K 2203/173 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016056 | Saykin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kebotix, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Kebotix, Inc. (Cambidge, Massachusetts) |
| INVENTOR(S) | Semion Saykin (Arlington, Massachusetts); Victoria Campbell (Somerville, Massachusetts); Selma Duhovic (Denver, Colorado); David Lee Wheeler (Brighton, Massachusetts); Kevin Ryan (Watertown, Massachusetts); Sreeletha Joby Eldo (Andover, Massachusetts); Nathan Darrell Peterson Ricke (Medford, Massachusetts); Zhongwei Hu (Newton Upper Falls, Massachusetts); Dennis Sheberla (Bedford, Massachusetts); Jhaylen McDavid (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure generally relates to emitting organic molecules, including but not limited to, pyrazoles such as 2-phenyl-2H-pyrazol-3-yl acetate, etc. In some cases, the molecules are able to emit in blue or green wavelengths. In some aspects, such molecules may be used in organic light emitting diodes. In certain embodiments, the molecules may comprise one or more bridge moieties and one or more chromophores. In some embodiments, these molecules can be used as electroluminescent media in devices requiring light emission as a function of applied voltage. Other embodiments of the disclosure are generally directed to systems and devices using such molecules, methods of using such molecules, e.g., to control the emission of light, kits involving such molecules, or the like. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/347714 |
| CURRENT CPC | Heterocyclic Compounds C07D 231/22 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Organic electric solid-state devices H10K 50/11 (20230201) H10K 85/654 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20240008819 | Wick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CAMERAD TECHNOLOGIES (Decatur, Georgia); THE UAB RESEARCH FOUNDATION (Birmingham, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carson Arthur Wick (Decatur, Georgia); Srini Tridandapani (Decatur, Georgia); Pamela T. Bhatti (Decatur, Georgia) |
| ABSTRACT | A system for determining subject orientation includes a medical imaging sensor configured to capture medical imagery of an imaging subject. The system also includes one or more interoceptive sensors, which are configured to obtain interoceptive sensor data indicative of an orientation associated with the system. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345347 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/70 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/70 (20170101) Image or Video Recognition or Understanding G06V 10/761 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240008939 | Hawkes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elliot Hawkes (Goleta, California); Tania Morimoto (San Diego, California) |
| ABSTRACT | A vine robot catheter device includes an elongate outer catheter dimensioned according to a path to reach a region of a targeted anatomy, an inverted vine robot extension having its proximal end attached to the outer catheter and its distal end partially or fully inverted into itself within the outer catheter during delivery to a target site, and a fluid path in the outer catheter to apply fluid pressure to the vine robot extension to actuate the vine robot extension to evert and extend the distal end out of and beyond the outer catheter. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 18/251904 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 2034/301 (20160201) A61B 2034/303 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0119 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009312 | D'AMATO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| INVENTOR(S) | Anthony R. D'AMATO (Ithaca, New York); Nicholas SCHAUB (Germantown, Maryland); Andrew Sante FIUMARA (Fayetteville, New York); Paul Michael TROIANO (Housatonic, Massachusetts); Jesus CARDENAS (Lake Forest, California); Ryan J. GILBERT (Wynantskill, New York) |
| ABSTRACT | Embodiments of the invention relate generally to electrospun fibers and, more particularly, to the controlled release of an active pharmaceutical ingredient (API) from electrospun fiber scaffolds (EFSs). |
| FILED | Monday, September 25, 2023 |
| APPL NO | 18/372165 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/465 (20130101) A61K 47/34 (20130101) Original (OR) Class Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) D01F 6/625 (20130101) Finishing or Dressing of Filaments, Yarns, Threads, Cords, Ropes or the Like D02J 13/003 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/041 (20130101) D10B 2509/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009350 | Kuo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Catherine K. Kuo (College Park, Maryland) |
| ABSTRACT | The present invention relates to enhancing mechanical properties of tissue such as collagenous or collagen-containing or elastin-containing tissue (e.g., tendons, ligaments, and cartilage) and treating related musculoskeletal and non-musculoskeletal conditions or injuries. |
| FILED | Wednesday, May 03, 2023 |
| APPL NO | 18/311592 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0048 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/3834 (20130101) A61L 2300/254 (20130101) A61L 2300/414 (20130101) A61L 2430/06 (20130101) A61L 2430/10 (20130101) A61L 2430/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009460 | Yazdan-Shahmorad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Azadeh Yazdan-Shahmorad (Seattle, Washington); Zixuan Zhou (Seattle, Washington); Karam Khateeb (Seattle, Washington); Mona Rahimi (Seattle, Washington); Aryaman Gala (Seattle, Washington) |
| ABSTRACT | Techniques for treating acute ischemic stroke, and other neurological pathologies, are described herein. An example method includes identifying a portion of a brain including overactive neurons and outputting an electrical signal to at least one stimulation electrode disposed away from the portion of the brain by a distance in a range of about 0.5 mm to 1 cm. The electrical signal includes a low-frequency component including bursts having a frequency in a range of about 2 Hz to about 10 Hz. The electrical signal includes a high-frequency component comprising pulses having a frequency in a range of about 200 Hz to about 2 kHz. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/219047 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/36064 (20130101) A61N 1/36067 (20130101) A61N 1/36103 (20130101) Original (OR) Class A61N 1/36139 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009630 | Tian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bozhi Tian (Chicago, Illinois); Aleksander Prominski (Chicago, Illinois); Lingyuan Meng (Chicago, Illinois) |
| ABSTRACT | This disclosure relates to methods for modulating activity of cells and tissue with materials that are capable of being activated by an energy pulse, such methods useful for treating diseases. The disclosure also provides devices and systems suitable for use in such methods, particularly devices and systems having a carbon-based material comprising one or more monolithic porous carbon membranes. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 18/254301 |
| CURRENT CPC | Separation B01D 67/0058 (20130101) Original (OR) Class B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 71/021 (20130101) B01D 2325/0283 (20220801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240009850 | Harnett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cindy Harnett (Louisville, Kentucky); Michael Seokyoung Han (Louisville, Kentucky) |
| ABSTRACT | An opto-electronic sensor includes a deformable body that has a gripping surface, securable to and movable by a gripper to a position at which the gripper surface contacts an object, and includes optical waveguides positioned within the deformable body, each optical waveguide including a gap. The deformable body is configured to exhibit a lateral deflection responsive to receiving via the gripping surface a lateral force from the object. The deformable body and the one or more optical waveguides are mutually configured to produce a corresponding change in the gap of the one or more optical waveguides responsive to the lateral deflection. The change in the gap is detectable as a change in a light intensity, by a light source and a light detector. The lateral force is computed using the detected change. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/220443 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/161 (20130101) B25J 9/1612 (20130101) B25J 9/1694 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010576 | Temme et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pivot Bio, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Pivot Bio, Inc. (Berkeley, California) |
| INVENTOR(S) | Karsten Temme (Oakland, California); Alvin Tamsir (San Francisco, California); Sarah Bloch (Emeryville, California); Rosemary Clark (Berkeley, California); Emily Tung (Millbrae, California) |
| ABSTRACT | Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria. Each member of the plurality comprises one or more genetic variations introduced into one or more genes or non-coding polynucleotides of the bacteria's nitrogen fixation or assimilation genetic regulatory network, such that the bacteria are capable of fixing atmospheric nitrogen in the presence of exogenous nitrogen. The bacteria are not intergeneric microorganisms. Additionally, the bacteria, in planta, produce 1% or more of the fixed nitrogen in the plant. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345783 |
| CURRENT CPC | Nitrogenous Fertilisers C05C 1/00 (20130101) C05C 3/005 (20130101) C05C 5/005 (20130101) C05C 11/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/80 (20130101) C12N 9/93 (20130101) C12N 9/0095 (20130101) Enzymes C12Y 118/06001 (20130101) C12Y 305/01002 (20130101) C12Y 603/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010673 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Minkyu Kim (Tucson, Arizona); David Storms Knoff (Tucson, Arizona); Samuel Kim (Tucson, Arizona) |
| ABSTRACT | Protein complexes are profound in various biological processes, and their ability to self-associate offers exciting opportunities for innovative biomaterials. However, the weak physical interactions within protein complexes result in limited mechanical stability and fast erosion rates, posing a significant challenge. Thus, a SAv-based hydrogel where SAv tetramers serve as crosslinking junctions is described herein. These mechanically reinforced SAv tetramers significantly enhanced the shear elasticity and decelerated the bioerosion process of the overall material. This simple approach to modulate the mechanical strength of protein complexes as crosslinking junctions present an attractive prospect for a myriad of biotechnological applications, such as biomimetic scaffolds and soft robotics. |
| FILED | Friday, August 04, 2023 |
| APPL NO | 18/365648 |
| CURRENT CPC | Peptides C07K 1/1077 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010687 | Baker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Baker (Seattle, Washington); Alexis Courbet (Seattle, Washington); Jesse Hansen (Seattle, Washington); Yang Hsia (Seattle, Washington); Neville Bethel (Seattle, Washington); Justin Kollman (Seattle, Washington) |
| ABSTRACT | Polypeptides that comprise axle or ring components of protein nanomachines, and kits and nanomachines including such polypeptides are disclosed herein. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931214 |
| CURRENT CPC | Peptides C07K 14/245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011026 | Nelles |
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| FUNDED BY |
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| APPLICANT(S) | Tacit Therapeutics, Inc. (South San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David A. Nelles (San Francisco, California) |
| ABSTRACT | Disclosed are methods and compositions for promoting trans-splicing. In some embodiments, the composition comprises an engineered small nuclear RNA that promotes trans-splicing of a target RNA molecule. The composition may further comprise an RNA donor molecule. |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/362698 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) Original (OR) Class C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011353 | ZHANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaosheng ZHANG (Berkeley, California); Ming Chiang A. WU (Moraga, California); Andrew S. MICHAELS (Berkeley, California); Johannes HENRIKSSON (Berkeley, California) |
| ABSTRACT | An integrated-optics MEMS-actuated beam-steering system is disclosed, wherein the beam-steering system includes a lens and a programmable vertical coupler array having a switching network and an array of vertical couplers, where the switching network can energize of the vertical couplers such that it efficiently emits the light into free-space. The lens collimates the light received from the energized vertical coupler and directs the output beam along a propagation direction determined by the position of the energized vertical coupler within the vertical-coupler array. In some embodiments, the vertical coupler is configured to correct an aberration of the lens. In some embodiments, more than one vertical coupler can be energized to enable steering of multiple output beams. In some embodiments, the switching network is non-blocking. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/370600 |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/34 (20130101) E06B 9/42 (20130101) E06B 9/80 (20130101) Original (OR) Class E06B 9/325 (20130101) E06B 9/326 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/292 (20130101) G02F 1/3132 (20130101) G02F 1/3137 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011776 | Roumeliotis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minnesota, Minnesota) |
| INVENTOR(S) | Stergios I. Roumeliotis (St Paul, Minnesota); Anastasios I. Mourikis (Minneapolis, Minnesota) |
| ABSTRACT | Localization and navigation systems and techniques are described. An electronic device comprises a processor configured to maintain a state vector storing estimates for a position of the electronic device at poses along a trajectory within an environment along with estimates for positions for one or more features within the environment. The processor computes, from the image data, one or more constraints based on features observed from multiple poses of the electronic device along the trajectory, and computes updated state estimates for the position of the electronic device in accordance with the motion data and the one or more computed constraints without computing updated state estimates for the features for which the one or more constraints were computed. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 18/051469 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/16 (20130101) G01C 21/165 (20130101) G01C 21/1656 (20200801) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/00 (20130101) Wireless Communication Networks H04W 4/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011876 | Anand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robbyn K. Anand (Ames, Iowa); Beatrise Berzina (Ames, Iowa) |
| ABSTRACT | High-throughput microfluidic devices comprising one or more fluidic microchannels each with at least one flow-through 3D structure comprising a 3D electrode, or alternatively a 3D permselective structure, and optional secondary bead bed(s) are disclosed. Such devices can be used for counter-flow focusing of charged species via ion concentration polarization and in situ quantification of electrokinetically enriched charged species from an ionically conductive solution by both optical and electrical detection. |
| FILED | Monday, June 12, 2023 |
| APPL NO | 18/332814 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1603 (20140204) A61M 1/1656 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/40 (20130101) Original (OR) Class G01N 1/2202 (20130101) G01N 2001/4038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240011903 — APPARATUSES AND METHODS FOR EXAMINING THE MOVEMENT OF CONSTITUENTS WITHIN TISSUE CELLS
| US 20240011903 | NOLTE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayettle, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David D. NOLTE (Lafayette, Indiana); Kwan JEONG (Nowon-gu, Seoul, South Korea); Maria Josef LOPERA (Medellin, Colombia); John J. TUREK (West Lafayette, Indiana) |
| ABSTRACT | Apparatuses and methods for investigating the inside of a tissue cell are disclosed. Embodiments include diffusely scattering light off a target sample, producing two crossing beams from the scattered light, and using a camera to create an image from the light. Some embodiments utilize a Fourier lens and a Fresnel biprism, and optionally include a long-coherence light source, a delay plate (which can be a polarization rotator or an optical flat), and/or a beam expander. Still further embodiments utilize a diffraction grating, a spatial filter (which may include two differently sized apertures), and a Fourier lens, and optionally include differently sized apertures in the spatial filter. Some embodiments include a transparent support and illuminating the target at an oblique angle through the transparent support. Still further embodiments utilize a low-coherence light source and/or immobilizing the sample tissue using surface bonding chemistry. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 18/036360 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/021 (20130101) G01J 3/0208 (20130101) G01J 9/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/474 (20130101) Original (OR) Class G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011925 | Chiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jungchih Chiao (Grand Prairie, Texas); Sen Bing (Dallas, Texas) |
| ABSTRACT | A system for noninvasive monitoring of water content comprising a radio-frequency (RF) planar resonant loop sensor comprising a planar loop antenna; and an element disposed within and co-planar with a loop formed by the planar loop antenna; and a vector network analyzer configured to be connected with the RF planar resonant loop sensor. |
| FILED | Wednesday, June 28, 2023 |
| APPL NO | 18/342881 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/6847 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/04 (20130101) Original (OR) Class G01N 33/18 (20130101) Antennas, i.e Radio Aerials H01Q 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012171 | ANDERSON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Brian ANDERSON (Mt. Airy, Maryland); Regupathi ANGAPPAN (Baltimore, Maryland); Robin BARNES (Elkridge, Maryland); Sabine STANLEY (Finksburg, Maryland); Sarah VINES (Baltimore, Maryland) |
| ABSTRACT | A computer-implemented method includes: receipt and accession of magnetic field data from a constellation of satellites providing global coverage over the Earth in a time span less than one day; inter-calibrating the magnetic field data from all satellites to a common standard; quantifying the global magnetic disturbance and selecting quiescent intervals at least as short as one day for evaluation of Earth's internally-generated field; calculating global maps of the mean vector magnetic field for each quiet interval from the average of all satellite measurements in angular bins; converting the time sequence of global maps of the mean fields to time series of angular harmonic coefficients via direct convolution; applying spectral and regression analysis to the harmonic coefficient time series to identify and remove artifacts in the signals; reconstructing a continuous time and spatial representation of the magnetic field continuous in time and angular position globally. |
| FILED | Thursday, September 02, 2021 |
| APPL NO | 18/023911 |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/36 (20130101) G01V 3/38 (20130101) G01V 3/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012309 | Weiner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Weiner (West Lafayette, Indiana); Poolad Imany (Boulder, Colorado) |
| ABSTRACT | A method of generating a photon with multiple dimensions includes a step of generating a first photon encoded with quantum information in each of two or more frequency bins and at least one time bin. The method further includes performing a frequency dependent time operation to entangle (i.e. make non-separable) the frequency bins and the time bins in the photon. |
| FILED | Monday, May 08, 2023 |
| APPL NO | 18/313409 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 3/00 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Transmission H04B 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012330 | Toombs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Joseph Toombs (Oakland, California); Hayden Taylor (Oakland, California) |
| ABSTRACT | A roll-to-roll computed axial lithography system includes an optical illumination system; an optical modulation system to receive light from the optical illumination system and to output an illumination pattern of light; and a web-handling system to receive and transport a web having a photosensitive material layer such that a portion of the web will be in an optical path of the modulation system. The web-handling system includes a development module to render three-dimensional structures from the layer exposed to the illumination pattern of light. The illumination pattern of light provides predetermined three-dimensional regions within a bulk of the layer that are exposed beyond a photo-responsive threshold for the photosensitive material providing volumetric patterning. The development module removes one of regions of the layer exposed beyond the photo-responsive threshold or regions of the layer that are not exposed beyond the photo-responsive threshold to provide a three-dimensional structure from the layer. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 18/271104 |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/30 (20130101) Original (OR) Class G03F 7/70191 (20130101) G03F 7/70733 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012412 | DU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jing DU (Gainesville, Florida); Pengxiang XIA (Gainesville, Florida); Fang XU (Gainesville, Florida); Qi ZHU (Gainesville, Florida) |
| ABSTRACT | A system, apparatus, and method are provided herein for remote control of a robotic device, and more particularly, to a haptic system for robot teleoperation. A system for robot teleoperation is provided including: an underwater robot vehicle; a subsea sensing module associated with the underwater robot vehicle; a workplace module; and a user interface, where the subsea sensing module senses an environment of the underwater robot vehicle and provides sensor data to the workplace module, where the workplace module reproduces the environment and instructs the user interface to provide sensory augmentation associated with the environment to an operator. The system of an example embodiment further includes a robot control module, where the user interface receives input from the operator and the robot control module controls the underwater robot vehicle according to the input. |
| FILED | Wednesday, June 28, 2023 |
| APPL NO | 18/343095 |
| CURRENT CPC | Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 11/52 (20130101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/005 (20130101) Original (OR) Class G05D 1/0038 (20130101) G05D 1/0206 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012728 | Nieh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jason Nieh (New York, New York); Ronghui Gu (New York, New York); Xuheng Li (New York, New York); Xupeng Li (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Nieh (New York, New York); Ronghui Gu (New York, New York); Xuheng Li (New York, New York); Xupeng Li (New York, New York) |
| ABSTRACT | Mechanisms for verifying software on a multi-CPU machine are provided, the mechanisms including: using a hardware processor: reordering, in a shared log, a first local CPU event from a local CPU operating on a shared object to be before at least one first prior oracle query corresponding to a prior event from another CPU based on whether the first local CPU event can be reordered with respect to the prior event without changing the multi-CPU machine's behavior with respect to the shared object; merging first consecutive oracle queries including the at least one first prior oracle query in the shared log; and verifying the software based on the merged first consecutive oracle queries. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/220229 |
| CURRENT CPC | Electric Digital Data Processing G06F 11/28 (20130101) Original (OR) Class G06F 11/3612 (20130101) G06F 11/3636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013800 | Mesgarani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nima Mesgarani (New York, New York); Yi Luo (New York, New York); James O'Sullivan (New York, New York); Zhuo Chen (New York, New York) |
| ABSTRACT | Disclosed are devices, systems, apparatus, methods, products, and other implementations, including a method comprising obtaining, by a device, a combined sound signal for signals combined from multiple sound sources in an area in which a person is located, and applying, by the device, speech-separation processing (e.g., deep attractor network (DAN) processing, online DAN processing, LSTM-TasNet processing, Conv-TasNet processing), to the combined sound signal from the multiple sound sources to derive a plurality of separated signals that each contains signals corresponding to different groups of the multiple sound sources. The method further includes obtaining, by the device, neural signals for the person, the neural signals being indicative of one or more of the multiple sound sources the person is attentive to, and selecting one of the plurality of separated signals based on the obtained neural signals. The selected signal may then be processed (amplified, attenuated). |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/228239 |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 17/26 (20130101) G10L 25/30 (20130101) Original (OR) Class G10L 25/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013853 | BAKER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David BAKER (Seattle, Washington); Basile WICKY (Seattle, Washington); Lukas MILLES (Seattle, Washington); Alexis COURBET (Seattle, Washington); Robert RAGOTTE (Seattle, Washington); Elias KINFU (Seattle, Washington); Sam TIPPS (Seattle, Washington); Justas DAUPARAS (Seattle, Washington); Ryan KIBLER (Seattle, Washington) |
| ABSTRACT | Polypeptide are providing that are at least 50% identical to the amino acid sequence selected from the group consisting of SEQ ID NOS:1-37, cyclic homo-oligomers of the polypeptides, and uses thereof. |
| FILED | Friday, July 07, 2023 |
| APPL NO | 18/348528 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/20 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014373 | SU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Laisuo SU (Pittsburgh, Pennsylvania); Baby REEJA-JAYAN (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method to form a coated cathode material may generally include forming, via chemical vapor deposition, an interfacial layer coating on an exterior surface of a cathode active material, wherein the interfacial layer comprises an organic polymer; and wherein the interfacial layer is substantially uniform on and conformal to the exterior surface of the cathode active material. The polymer may include poly(3,4-ethylenedioxythiophene) (PEDOT). Methods of making and using the same are also described. |
| FILED | Monday, September 18, 2023 |
| APPL NO | 18/369331 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/00 (20130101) C23C 16/44 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) H01M 4/0428 (20130101) H01M 4/0471 (20130101) Original (OR) Class H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/624 (20130101) H01M 4/1391 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240011776 | Roumeliotis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minnesota, Minnesota) |
| INVENTOR(S) | Stergios I. Roumeliotis (St Paul, Minnesota); Anastasios I. Mourikis (Minneapolis, Minnesota) |
| ABSTRACT | Localization and navigation systems and techniques are described. An electronic device comprises a processor configured to maintain a state vector storing estimates for a position of the electronic device at poses along a trajectory within an environment along with estimates for positions for one or more features within the environment. The processor computes, from the image data, one or more constraints based on features observed from multiple poses of the electronic device along the trajectory, and computes updated state estimates for the position of the electronic device in accordance with the motion data and the one or more computed constraints without computing updated state estimates for the features for which the one or more constraints were computed. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 18/051469 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/16 (20130101) G01C 21/165 (20130101) G01C 21/1656 (20200801) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/00 (20130101) Wireless Communication Networks H04W 4/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011863 | BANERJEE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (COLUMBIA, South Carolina); ADVENT INNOVATIONS LTD. CO. (COLUMBIA, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SOURAV BANERJEE (IRMO, South Carolina); MUSTAHSEEN M. INDALEEB (WEST COLUMBIA, South Carolina); SHAWN BEARD (BISHOP, California); RITUBARNA BANERJEE (COLUMBIA, South Carolina) |
| ABSTRACT | The disclosure deals with a system and method for Compressive Sensing, which has been shown to greatly reduce data acquisition and processing burdens by providing mathematical guarantees for accurate signal recovery from far fewer samples than conventionally needed. A generalized Compressive Sensing methodology developed for automated reduction of non-destructive evaluation/structural health monitoring (NDE/SHM) data is effective for multiple types of NDE/SHM systems. The methodology uses Compressive Sensing at two stages in the data acquisition and analysis process to detect damage. The two stages are: (1) temporally undersampled sensor signals from (2) spatially undersampled sensor arrays, resulting in faster data acquisition and reduced data sets without any loss in damage detection ability. In addition, a graphical user interface helps guide and visualize the associated data reconstruction process. |
| FILED | Wednesday, May 03, 2023 |
| APPL NO | 18/311359 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 5/0033 (20130101) Original (OR) Class G01M 5/0066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013019 | Fink et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NASA Johnson Space Center (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick W. Fink (Houston, Texas); Greg Y. Lin (Houston, Texas); Phong H. Ngo (Houston, Texas); David S. Hafermalz (Houston, Texas); Raymond S. Wagner (Houston, Texas); Lazaro D. Rodriguez (Houston, Texas) |
| ABSTRACT | A radio-frequency identification (RFID) antenna assembly, per an implementation, includes a number of multiplexer modules coupled with one another. Radio frequency (RF) signals are received from an RFID reader. One or more of the multiplexer modules has a switch with multiple output ports. An antenna connects with one of the output ports and, per an implementation, an encoder connects with another of the output ports. The multiplexer module(s) may also have a first rectifier for rapid self-powering capabilities, and a second rectifier for more robust self-powering capabilities. |
| FILED | Wednesday, July 06, 2022 |
| APPL NO | 17/810890 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0701 (20130101) G06K 19/0724 (20130101) Original (OR) Class G06K 19/07345 (20130101) Antennas, i.e Radio Aerials H01Q 1/2208 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240013531 | Hu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chuanmin Hu (St. Petersburg, Florida) |
| ABSTRACT | Methods and systems for macroalgae or marine debris detection are disclosed. A method includes accessing or receiving multispectral aerial images of a target region; preprocessing the aerial images; determining, using one or more characteristics of the aerial images, an image type for each of the aerial images; generating the one or more geospatial data images by: providing preprocessed aerial images of each image type to a machine learning algorithm trained using images having that image type; receiving, as outputs from each DCNN, image data indicating whether macroalgae are present in regions corresponding to each pixel of the aerial images; altering pixel values of the aerial images to visually indicate the presence of macroalgae in regions corresponding to the altered pixel values; and providing the one or more geospatial data images to the user device via a user interface. Other aspects, embodiments, and features are also claimed and described. |
| FILED | Wednesday, June 14, 2023 |
| APPL NO | 18/335002 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 11/04 (20130101) Image or Video Recognition or Understanding G06V 10/58 (20220101) G06V 10/60 (20220101) G06V 10/82 (20220101) G06V 10/273 (20220101) G06V 10/774 (20220101) G06V 20/13 (20220101) Original (OR) Class G06V 20/194 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014014 | GOEBEL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan M. GOEBEL (TARZANA, California); Adele R. PAYMAN (PASADENA, California) |
| ABSTRACT | A heaterless hollow cathode with high current discharge capability for use in electric propulsion devices is presented. The heaterless hollow cathode includes a thermionic emitter insert having a tubular shape and arranged inside a hollow cathode tube. The heaterless hollow cathode further includes a propellant feed tube that longitudinally extends from an upstream region of the hollow cathode tube into an inner volume of the insert. According to one aspect, an extension of the propellant feed tube into the inner volume of the insert is in a range from one quarter to three quarters of a total longitudinal length of the insert. The propellant feed tube is made of a refractory metal that is capable of withstanding temperatures above 2200 degrees C. with negligible evaporation. According to another aspect, the refractory metal is tantalum or tungsten. |
| FILED | Wednesday, June 21, 2023 |
| APPL NO | 18/339194 |
| CURRENT CPC | Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0075 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/32596 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014568 | CHAHAT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nacer E. CHAHAT (Altadena, California); Gaurangi GUPTA (Pasadena, California); John L. WOLFF (Pasadena, California); Adrian J. TANG (Pasadena, California); Goutam CHATTOPADHYAY (Pasadena, California) |
| ABSTRACT | A metal-only flat metasurface antenna is described. The antenna includes a pillbox beamformer combined with a metasurface structure provided by an array of non-resonant subwavelength unit elements having opening sizes that are strictly smaller than half of the guided-mode wavelength. The pillbox beamformer includes bottom and top parallel plate waveguides (PWPs) forming respective bottom and top cavities for propagation of the guided-mode. Bottom, middle and top metal plates form the two PWPs. Arranged at one end of the bottom and top PWPs is a respective parabolic structure. An all-metal horn structure is centrally arranged at a second end of the bottom PWP opposite the parabolic structure. According to one aspect, the horn structure includes a single feed port arranged at a focal point of the parabolic structure. According to another aspect, the horn structure includes two feed ports arranged at an offset of the focal point. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/348300 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 15/0086 (20130101) Original (OR) Class H01Q 19/132 (20130101) H01Q 19/138 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20240011928 | Potyrailo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Janell Marie Crowder (Clifton Park, New York) |
| ABSTRACT | A system and a method for multi-gas sensing using dielectric excitation of a single sensing material operated at a single operating temperature. Contrary to conventional gas sensor designs, embodiments of the gas sensors disclosed herein implement a metal oxide semiconductor sensing material maintained at a constant temperature, wherein dielectric excitation responses of the sensing material are measured at this constant temperature while the sensing material is exposed to a fluid sample. The disclosed gas sensors and gas sensing methods unexpectedly provide desirable characteristics, such as enhanced multi-gas differentiation, while operating at the constant operating temperature. For example, by measuring dielectric excitation responses of using at least one gas sensing element at a single operating temperature, the disclosed gas sensors and gas sensing methods demonstrate superior multi-gas differentiation compared to other gas sensors and other gas sensing methods that rely on multiple resistance measurements performed at several different operating temperatures. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859874 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 27/221 (20130101) Original (OR) Class G01N 33/0027 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240011934 | Potyrailo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Baokai Cheng (Niskayuna, New York); Janell Marie Crowder (Clifton Park, New York) |
| ABSTRACT | An electrochemical gas sensor for multi-gas analysis of a fluid sample includes an electrochemical gas sensing element and a data collection component. The data collection component is configured to cycle the electrochemical gas sensing element between first excitation and signal detection values and second excitation and signal detection values at a predetermined time constant, and to measure responses of the electrochemical gas sensor to the fluid sample at the first excitation and signal detection values and the second excitation and signal detection values wherein the responses of the electrochemical gas sensor to the fluid sample at the first excitation and signal detection values and the second excitation and signal detection values are indicative of identities, respective concentrations, or a combination thereof, of at least two analyte gases of the fluid sample. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859921 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/404 (20130101) Original (OR) Class G01N 27/413 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014337 | KOTOV et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas KOTOV (Ann Arbor, Michigan); Drew VECCHIO (Ann Arbor, Michigan); Brandon DAVIS (Ann Arbor, Michigan); Mark HAMMIG (Dexter, Michigan) |
| ABSTRACT | A device for radiation detection includes a first electrode, a second electrode spaced apart from the first electrode, and a macroscale structure disposed between the first electrode and the second electrode. The macroscale structure comprises a composite arrangement of nanocrystalline particles. The nanocrystalline particles comprise a lead chalcogenide material. The nanocrystalline particles establish conductive paths between the first electrode and the second electrode without an intervening conductive polymer agent. |
| FILED | Wednesday, July 05, 2023 |
| APPL NO | 18/218360 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/241 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/085 (20130101) H01L 31/0324 (20130101) H01L 31/0384 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20240009118 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hong Li (Newark, Delaware); Kenneth C. Elliott (Germantown, Maryland) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Hong Li (Newark, Delaware); Kenneth C. Elliott (Germantown, Maryland) |
| ABSTRACT | The invention provides a method for vaccinating one or more avians in need thereof. The vaccination method comprises administering to the one or more avians a stable foam in an amount effective for inducing a neutralizing immune response against an infectious pathogen in the one or more avians. The foam comprises a gas and a liquid, and the liquid comprises a vaccine and a foaming agent. The avian may be a chick. Also provided is a method for preparing the stable foam. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/350357 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0056 (20130101) Original (OR) Class A61K 39/215 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) A61K 2039/552 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010964 | Jiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shan Jiang (Ames, Iowa); Kyle Miller (Ames, Iowa); Connor Phelps Thorpe (Ames, Iowa); Alan Eggenberger (Ames, Iowa); Kan Wang (Ames, Iowa) |
| ABSTRACT | Improved biolistic bombardment is observable when using a modification to a double-barrel device. One such modification is a custom attachment that can be retrofit to a standard helium-based gene gun. The custom attachment facilitates DNA and protein delivery. The attachment confines the flow of particles in a barrel similar to the choke on a shotgun barrel. |
| FILED | Friday, July 07, 2023 |
| APPL NO | 18/348689 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 35/00 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/895 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20240011894 | Germer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Avery Germer (Montgomery Village, Maryland) |
| ABSTRACT | Embodiments of the present invention relate to an ellipsometer that includes a combination of a plurality of reflective devices to measure a Mueller matrix reflectance of a material in the VUV and EUV region. Ellipsometer in accordance with embodiments of the present invention relate to an ellipsometer that includes a multi-mirror polarization state generator combined with a multi-mirror polarization state analyzer and a detector to realize a Mueller matrix ellipsometer. Embodiments of the present invention utilize two rotating assemblies with each assembly including multiple mirrors that combine to act as amplitude and phase retarders. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/218692 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/211 (20130101) Original (OR) Class G01N 2021/214 (20130101) G01N 2021/215 (20130101) G01N 2201/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240014903 | Long et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Alexander Long (Bethesda, Maryland); Benjamin James Reschovsky (Cabin John, Maryland) |
| ABSTRACT | Disclosed is a direct digital chirp synthesizer for generating a chirped optical frequency comb that includes: a direct digital synthesizer that receives a repetition frequency signal from a delay generator, receives a clock frequency from a frequency converter, produces a radiofrequency chirp waveform based on the repetition frequency signal and the clock frequency, and communicates the radiofrequency chirp waveform; and an electro optic modulator in electrical communication with the direct digital synthesizer and that receives the radiofrequency chirp waveform from the direct digital synthesizer, receives laser light, and produces the chirped optical frequency comb from the laser light based on the radiofrequency chirp waveform. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 18/035896 |
| CURRENT CPC | Transmission H04B 10/504 (20130101) Original (OR) Class H04B 10/508 (20130101) H04B 10/556 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20240008808 | Woodard |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven Hartwell Woodard (Palo Alto, California) |
| ABSTRACT | A portable polysomnography apparatus comprises a unitary flexible structured pillow that is embedded with one or more sensors for data collection. The one or more sensors can comprise a tilt sensor that is configured to generate respiratory effort signals based on tilting of the head of the subject on the pillow. The one or more sensors can further be configured to generate ballistocardiogram signals from movement of the head of the subject caused by beating of the heart of the subject. The polysomnography apparatus can be advantageously sized and shaped to cause the sleeping subject to properly orient her head with respect to the sensors for optimal data collection while the subject is asleep. |
| FILED | Friday, September 22, 2023 |
| APPL NO | 18/472497 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0205 (20130101) A61B 5/1102 (20130101) A61B 5/6892 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240010838 | HELGASON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VitroLabs Inc (Milpitas, California); King's College London (London, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ingvar HELGASON (South San Francisco, California); Dusko ILIC (London, United Kingdom) |
| ABSTRACT | Disclosed herein are synthetic leathers, artificial epidermal layers, artificial dermal layers, layered structures, products produced therefrom and methods of producing the same. |
| FILED | Wednesday, July 05, 2023 |
| APPL NO | 18/347349 |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 89/06 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0625 (20130101) C12N 5/0629 (20130101) C12N 5/0698 (20130101) C12N 11/02 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2502/13 (20130101) C12N 2502/091 (20130101) C12N 2502/094 (20130101) C12N 2506/45 (20130101) C12N 2533/30 (20130101) C12N 2533/54 (20130101) Chemical Treatment of Hides, Skins or Leather, e.g Tanning, Impregnating, Finishing; Apparatus Therefor; Compositions for Tanning C14C 3/02 (20130101) C14C 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Central Intelligence Agency (CIA)
| US 20240014419 | Blass |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Central Intelligence Agency (Washington, District of Columbia) |
| ASSIGNEE(S) | Central Intelligence Agency (Washington, District of Columbia) |
| INVENTOR(S) | Samuel D. Blass (Paramus, New Jersey) |
| ABSTRACT | A fuel cell supply device having a dehumidifier, a chamber, a first heat exchanger, and a reactor. The dehumidifier is connected to the chamber via a first conduit and a second conduit and is connected to the first heat exchanger via a third conduit. Further, the dehumidifier is configured to receive a first solution from the chamber via the first conduit. The chamber is connected to the first heat exchanger via a fourth conduit and is configured to receive from the dehumidifier a second solution via the second conduit. The first heat exchanger is connected to the reactor via a fifth conduit and is configured to receive and cool vapor from the chamber via the fourth conduit and cool dehumidified air received from the dehumidifier via the third conduit. The reactor is configured to connect to a fuel cell and receive cooled vapor from the first heat exchanger via the fifth conduit. Further, the reactor encloses therein one or more metals to react with the cooled vapor. |
| FILED | Monday, July 11, 2022 |
| APPL NO | 17/861299 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04014 (20130101) H01M 8/04164 (20130101) Original (OR) Class H01M 8/04201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Classified Government Agency
| US 20240011751 | Adasczik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Walter K. Adasczik (Nashua, New Hampshire); Jeffrey A. Lizotte (Dracut, Massachusetts); Peter H. Remeis (Pelham, New Hampshire); Nicholas Collard (Nashua, New Hampshire) |
| ABSTRACT | A switch assembly and a method of effecting a battery to initiate. The switch assembly includes a support that is adapted to operably engage with a battery. The switch assembly also include a slide operably engaged with the support and moveable in a first direction relative to the support between a primed position and a released position. The switch assembly also includes a cover operably engaged with the support and enclosing the slide. The switch assembly also includes a firing pin mechanism operably engaged with the support, the slide, and the cover and moveable in a second direction relative to the slide and the support. In the switch assembly, the second direction of the firing pin mechanism is different than the first direction of the slide. |
| FILED | Wednesday, July 06, 2022 |
| APPL NO | 17/858432 |
| CURRENT CPC | Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/21 (20130101) Original (OR) Class Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 3/32 (20130101) H01H 9/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 20240009346 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Beth Israel Deaconess Medical Center (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xuanhe Zhao (Aliston, Massachusetts); Hyunwoo Yuk (Cambridge, Massachusetts); Heejung Roh (Cambridge, Massachusetts); Aristidis Veves (Westwood, Massachusetts); Georgios Theocharidis (Cambridge, Massachusetts) |
| ABSTRACT | A shape memory adhesive material for adhering and contracting wounds, particularly diabetic wounds, to facilitate their closure and healing. The shape memory adhesive is pre-stretched and dried to provide an adhesive structure with a pre-programmed strain, wherein the adhesive is capable of rapid robust adhesion followed by predictive contraction upon contact with a wet surface. According to preferred embodiments, the shape memory adhesive material includes a combination of one or more hydrophilic polymers or copolymers, one or more amine coupling group, and one or more cross linkers. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/669442 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/008 (20130101) Original (OR) Class A61L 26/0033 (20130101) A61L 26/0038 (20130101) A61L 26/0052 (20130101) A61L 26/0066 (20130101) A61L 26/0095 (20130101) A61L 2400/16 (20130101) A61L 2430/34 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 11/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20240010838 | HELGASON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VitroLabs Inc (Milpitas, California); King's College London (London, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ingvar HELGASON (South San Francisco, California); Dusko ILIC (London, United Kingdom) |
| ABSTRACT | Disclosed herein are synthetic leathers, artificial epidermal layers, artificial dermal layers, layered structures, products produced therefrom and methods of producing the same. |
| FILED | Wednesday, July 05, 2023 |
| APPL NO | 18/347349 |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 89/06 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0625 (20130101) C12N 5/0629 (20130101) C12N 5/0698 (20130101) C12N 11/02 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2502/13 (20130101) C12N 2502/091 (20130101) C12N 2502/094 (20130101) C12N 2506/45 (20130101) C12N 2533/30 (20130101) C12N 2533/54 (20130101) Chemical Treatment of Hides, Skins or Leather, e.g Tanning, Impregnating, Finishing; Apparatus Therefor; Compositions for Tanning C14C 3/02 (20130101) C14C 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20240013077 | Inoue et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ken Inoue (Elmsford, New York); Maika Takita (Croton-on-Hudson, New York); Antonio Corcoles-Gonzalez (Mount Kisco, New York); Scott Douglas Lekuch (New York, New York) |
| ABSTRACT | Systems, computer-implemented methods, and computer program products that can facilitate determining a state of a qubit are described. According to an embodiment, a system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can comprise an output receiving component that can receive, in response to a request, output representative of a quantum state of a qubit of a quantum computing device, and a classifying component that classifies the quantum state of the qubit of the quantum computing device based on the output representative of the quantum state of the qubit. The system can further include a configuring component that can configure the classifying component based on a characteristic of the request. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183602 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) G06F 18/2411 (20230101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class G06N 10/20 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20240010576 | Temme et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pivot Bio, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Pivot Bio, Inc. (Berkeley, California) |
| INVENTOR(S) | Karsten Temme (Oakland, California); Alvin Tamsir (San Francisco, California); Sarah Bloch (Emeryville, California); Rosemary Clark (Berkeley, California); Emily Tung (Millbrae, California) |
| ABSTRACT | Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria. Each member of the plurality comprises one or more genetic variations introduced into one or more genes or non-coding polynucleotides of the bacteria's nitrogen fixation or assimilation genetic regulatory network, such that the bacteria are capable of fixing atmospheric nitrogen in the presence of exogenous nitrogen. The bacteria are not intergeneric microorganisms. Additionally, the bacteria, in planta, produce 1% or more of the fixed nitrogen in the plant. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345783 |
| CURRENT CPC | Nitrogenous Fertilisers C05C 1/00 (20130101) C05C 3/005 (20130101) C05C 5/005 (20130101) C05C 11/00 (20130101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/08 (20130101) Original (OR) Class Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/80 (20130101) C12N 9/93 (20130101) C12N 9/0095 (20130101) Enzymes C12Y 118/06001 (20130101) C12Y 305/01002 (20130101) C12Y 603/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20240009271 | McIntyre et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aravive Inc (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gail McIntyre (Lansdale, Pennsylvania); David Prohaska (Madison, Wisconsin); Ray Tabibiazar (Chattanooga, Tennessee) |
| ABSTRACT | Compositions and methods are provided for treating a human metastatic cancer in a mammal by administering a therapeutic dose of a pharmaceutical composition that inhibits AXL protein activity, for example by inhibition of the binding interaction between AXL and its ligand GAS6. |
| FILED | Tuesday, August 01, 2023 |
| APPL NO | 18/228879 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20240013137 | Dearing |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen M. Dearing (Herndon, Virginia) |
| ABSTRACT | Systems and methods for dynamic routing of delivery resources for delivery of items from a pickup location on or near a first planned route to a delivery location on or near a second planned route. Methods can include identifying a first route and a second route based on the pickup and delivery locations, selecting one of a predetermined plurality of transfer nodes based on the locations of the first and second routes, and sending instructions to resources traveling along the first and second routes to meet and transfer the items at the selected transfer node. |
| FILED | Monday, September 25, 2023 |
| APPL NO | 18/473634 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0833 (20130101) G06Q 10/08355 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20240010516 | Wyrsta |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LIXIVIA, INC. (Santa Barbara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael D Wyrsta (Santa Barbara, California) |
| ABSTRACT | Methods for utilizing waste products of the steel industry are provided that utilize spent pickle liquor to recover valuable alkaline earth metals from low value wastes with significant calcium content in the form of insoluble oxide, hydroxides, and/or salts are provided, as well as methods for generating a ferric oxide hydroxide composite from steel slag. Suitable raw materials include slag from steel manufacturing and ash from various operations. Ferric oxide hydroxide composite materials described herein can be used for removal of sulfur and metals from contaminated materials. Accordingly, compositions and methods of the inventive concept introduce considerable value to low value waste materials that would otherwise be discarded. In addition, compositions and methods of the inventive concept serve to reduce waste streams from industrial processes. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 18/025278 |
| CURRENT CPC | Separation B01D 53/48 (20130101) B01D 53/81 (20130101) B01D 2253/1124 (20130101) B01D 2256/245 (20130101) B01D 2257/30 (20130101) B01D 2257/60 (20130101) B01D 2258/05 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/06 (20130101) B01J 20/3085 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 11/28 (20130101) C01F 11/32 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240012127 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | James D. Campbell (Hermosa Beach, California); Charles T. Hansen (Palos Verdes Estates, California) |
| ABSTRACT | A circuit comprises a receive processing window formation subsystem, a matched filter subsystem, a keystone interpolation subsystem, a phase modulation subsystem, and an image forming subsystem. The receive processing window formation subsystem forms, for each radar return from a scene, a receive processing window containing the radar return as an unbroken radar return. The matched filter subsystem creates a motion model for a reference point target disposed at a predetermined location within the scene, based on a set of motion compensation parameters for range and range rate, to compensate for at least some effects of fast time Doppler on the reference point target. The keystone interpolation subsystem rescales slow time information from the matched filter subsystem. A phase modulation subsystem applies phase modulations to a keystone-interpolated 2-D output array of information associated with the scene, to ensure proper registration in a range-Doppler map output of the scene. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/643639 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/2883 (20210501) G01S 13/003 (20130101) G01S 13/53 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, January 11, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240111.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page