FedInvent™ Patent Applications
Application Details for Thursday, January 18, 2024
This page was updated on Tuesday, June 18, 2024 at 02:11 PM GMT
Department of Health and Human Services (HHS)
| US 20240016384 | Lustig et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shimon Michael Lustig (Moraga, California); Ana Claudia Arias (Lafayette, California); Joseph R. Corea (Berkeley, California); Anit M. Flynn (Oakland, California) |
| ABSTRACT | Magnetic Resonance Imaging (MRI) receiver coil devices, including a MRI receiver coil or MRI receiver coil arrays, for use in a MRI guided High Intensity Focused Ultrasound system, and methods for manufacturing the same. A MRI receive coil device includes a flexible substrate having a first surface and a second surface opposite the first surface, and a pattern of conductive material formed on one or both of the first and second surfaces, the pattern including at least one receive coil and at least one capacitor, wherein the flexible substrate comprises a dielectric plastic material. In certain aspects, at least one layer of hydrophobic material covers the at least one receive coil and the at least one capacitor. |
| FILED | Tuesday, July 25, 2023 |
| APPL NO | 18/358754 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0036 (20180801) Original (OR) Class A61B 5/055 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4814 (20130101) G01R 33/34007 (20130101) G01R 33/34084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016561 | Majewicz Fey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ann Majewicz Fey (Austin, Texas); Jacob R. Boehm (Bedford, Texas); Nicholas P. Fey (Jonestown, Texas) |
| ABSTRACT | Systems, methods and computer program products for online recognition of bimanual or bipedal coordination modes directed to completing a task using a robot. Such a method includes the steps of determining an onset of bimanual or bipedal motion of a subject operating the robot, and, in response, receiving trajectory data of left and right hands, or left and right feet, of the subject. The method also includes the step(s) of computing, based on the trajectory data, geometric descriptors of the segment, which include a direction metric and a symmetry metric. The method further includes the step(s) classifying, based on the direction and symmetry metrics, the types of direction and symmetry for the segment. The method also includes at least one of the steps of: generating task performance feedback, and controlling the robot, based on the types of direction and symmetry. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/348329 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00 (20130101) A61B 34/25 (20160201) A61B 34/37 (20160201) Original (OR) Class A61B 2017/00207 (20130101) A61B 2034/252 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016629 | LENZI et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tommaso LENZI (Salt Lake City, Utah); Sarah HOOD (Salt Lake City, Utah); Lukas GABERT (Salt Lake City, Utah) |
| ABSTRACT | A powered joint system that is configured to adaptively control powered joint movement during movement tasks includes a knee joint, one or more sensors, and a controller. The one or more sensors are configured to capture sensor data associated with a residual limb of a user. The controller comprises one or more processors and one or more hardware storage devices storing instructions that are executable by the one or more processors to configure the controller to perform various acts, including to: obtain a thigh orientation term, a thigh angular velocity term, and a thigh vertical acceleration term based on the sensor data; determine a target knee angle based on the thigh orientation term, the thigh angular velocity term, and the thigh vertical acceleration term; and output a signal configured to cause the knee joint to move toward the respective target joint angles. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 18/032924 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/64 (20130101) Original (OR) Class A61F 2/6607 (20130101) A61F 2002/704 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016737 | Thaxton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | C. Shad Thaxton (Chicago, Illinois); Chad A. Mirkin (Wilmette, Illinois); Kaylin McMahon (Chicago, Illinois); Sushant Tripathy (Evanston, Illinois); Raja Kannan Mutharasan (Chicago, Illinois); David M. Leander (St. Louis, Missouri); Andrea J. Luthi (Evanston, Illinois) |
| ABSTRACT | Articles, compositions, kits, and methods relating to nanostructures, including synthetic nanostructures, are provided. Certain embodiments described herein include structures having a core-shell type arrangement; for instance, a nanostructure core may be surrounded by a shell including a material, such as a lipid bilayer, and may include other components such as oligonucleotides. In some embodiments, the structures, when introduced into a subject, can be used to deliver nucleic acids and/or can regulate gene expression. Accordingly, the structures described herein may be used to diagnose, prevent, treat or manage certain diseases or bodily conditions. In some cases, the structures are both a therapeutic agent and a diagnostic agent. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/456371 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/24 (20130101) A61K 47/64 (20170801) A61K 47/6925 (20170801) A61K 48/0033 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016768 | Dewji |
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| FUNDED BY |
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| APPLICANT(S) | Cura Therapeutics, LLC (La Jolla, California) |
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| INVENTOR(S) | Nazneen Dewji (San Deigo, California) |
| ABSTRACT | Provided herein are pharmaceutical compositions, each comprising a phenylsulfonamide, for example, a compound of Formula I, or an enantiomer, a mixture of enantiomers, a mixture of two or more diastereomers, a tautomer, a mixture of two or more tautomers, or an isotopic variant thereof; or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof; and a pharmaceutically acceptable excipient. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a neurodegenerative disease. |
| FILED | Friday, June 02, 2023 |
| APPL NO | 18/205283 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/18 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016777 | Flaumenhaft et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
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| INVENTOR(S) | Robert Flaumenhaft (Newton, Massachusetts); Lin Lin (Brookline, Massachusetts) |
| ABSTRACT | The present application provides a compound of Formula (I), or a pharmaceutically acceptable salt thereof. Pharmaceutical compositions containing the compound of Formula (I), and methods of using the compound of Formula (I) for treating viral infections and inhibiting thromobosis are also provided. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 18/252502 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 31/353 (20130101) Original (OR) Class A61K 31/7048 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016804 | Garovic et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vesna D. Garovic (Rochester, Minnesota); Tamar Tchkonia (Rochester, Minnesota); James L. Kirkland (Rochester, Minnesota) |
| ABSTRACT | This document relates to methods and materials for assessing and/or treating hypertensive disorders of pregnancy (e.g., preeclampsia) and/or one or more comorbidities associated with a hypertensive disorder of pregnancy. For example, methods and materials for determining if a female mammal has, or is likely to develop, a hypertensive disorder of pregnancy are provided. In addition, methods for using one or more senotherapeutic agents to treat a female mammal having, or at risk of developing, a hypertensive disorder of pregnancy (e.g., preeclampsia) are provided. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 17/632958 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/12 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/689 (20130101) G01N 2800/368 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016829 | Machielse et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mandos LLC (West Hollywood, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bernardus Nicolaas Machielse (North Potomac, Maryland); Allan Darling (North Potomac, Maryland) |
| ABSTRACT | This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C. |
| FILED | Monday, May 01, 2023 |
| APPL NO | 18/141832 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/724 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016830 | Golobish et al. |
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| APPLICANT(S) | CytoSorbents, Inc. (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Golobish (Princeton, New Jersey); Maryann Gruda (Yardley, Pennsylvania); Tamaz Guliashvili (Philadelphia, Pennsylvania); Pamela O'Sullivan (Manalapan, New Jersey); Andrew Scheirer (Hoboken, New Jersey); Vi Dan (East Brunswick, New Jersey); Wei-Tai Young (Hillsborough, New Jersey); Vincent Capponi (Lawrenceville, New Jersey); Phillip Chan (Cherry Hill, New Jersey) |
| ABSTRACT | The invention concerns biocompatible polymer systems comprising at least one polymer with a plurality of pores, said polymer comprising a sulfonic acid salt functionality designed to adsorb a broad range of protein based toxins from less than 0.5 kDa to 1,000 kDa and positively charged ions including but not limited to potassium. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345683 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/795 (20130101) Original (OR) Class A61K 47/20 (20130101) A61K 47/26 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3679 (20130101) A61M 5/165 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/264 (20130101) B01J 20/267 (20130101) B01J 20/28069 (20130101) B01J 39/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016838 | Swaminathan et al. |
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| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California) |
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| INVENTOR(S) | Srividya Swaminathan (Duarte, California); Anil Kumar (Duarte, California); Sung June Lee (Duarte, California); Adeleh Taghi Khani (Duarte, California); Chun-Wei Chen (Duarte, California) |
| ABSTRACT | Provided herein, inter alia, are compositions including engineered NK cells and methods for preparing the same. The engineered NK cells provided herein include integrated nucleic acid sequences encoding Cas9 proteins (e.g. dCas9). The engineered NK cells are contemplated to be effective for treating and/or preventing cancer, particularly leukemia. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 18/033777 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2740/15043 (20130101) C12N 2800/80 (20130101) C12N 2830/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016847 | DANINO et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Tal DANINO (Brooklyn, New York); Nicholas ARPAIA (New York, New York); Rosa VINCENT (New York, New York); Thomas SAVAGE (Bronx, New York); Jongwon IM (New York, New York); Candice GURBATRI (Dix Hills, New York) |
| ABSTRACT | A system combining programmable bacteria cells that produce one or more antigens and optionally one or more cytokines and CAR-T cells that recognize and respond to at least one of the antigens to elicit an immune response against tumors and treat hyperproliferative disorders. |
| FILED | Thursday, August 17, 2023 |
| APPL NO | 18/451576 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 35/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) C12N 5/0636 (20130101) C12N 15/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016848 | Epstein et al. |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Epstein (Radnor, Pennsylvania); Haig Aghajanian (Lafayette Hill, Pennsylvania); Steven M. Albelda (Philadelphia, Pennsylvania); Ellen Puré (Bryn Mawr, Pennsylvania) |
| ABSTRACT | The present invention includes compositions and methods for treating heart disease and/or heart failure. In one embodiment, the treatment includes administering to the subject a cell genetically modified to express a chimeric antigen receptor (CAR), comprising an antigen binding domain specific for fibroblast activation protein (FAP). In another embodiment, the treatment includes administering a cell genetically modified to express a T cell receptor (TCR) specific for an activated fibroblast. |
| FILED | Wednesday, September 06, 2023 |
| APPL NO | 18/462149 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/04 (20180101) Peptides C07K 16/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016858 | Sonnenburg et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
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| INVENTOR(S) | Justin L. Sonnenburg (Redwood City, California); Weston R. Whitaker (Daly City, California); Elizabeth Stanley (Portola Valley, California) |
| ABSTRACT | Provided are nucleic acids that include a promoter, where the promoter is operable in a Bacteroides cell and is operably linked to a heterologous nucleotide sequence of interest. Also provided are nucleic acids that include a promoter (operable in a prokaryotic cell such as a Bacteroides cell) operably linked to a sequence encoding a synthetic ribosomal binding site (RBS). Also provided are fusion proteins (and nucleic acids encoding them) in which a secreted Bacteroides polypeptide is fused to a heterologous polypeptide of interest. Also provided are prokaryotic cells (e.g., E. coli, a Bacteroides cell, and the like) that include one more nucleic acids such as those described above. Also provided are methods of expression in a prokaryotic cell, methods of detectably labeling a Bacteroides cell in an animal's gut, and methods of delivering a protein to an individual's gut. |
| FILED | Thursday, August 10, 2023 |
| APPL NO | 18/447700 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 38/00 (20130101) Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0069 (20130101) C12N 15/52 (20130101) C12N 15/70 (20130101) C12N 15/74 (20130101) C12N 15/90 (20130101) Enzymes C12Y 113/12005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240016859 — MICROENCAPSULATED AND CHROMOSOME INTEGRATED COMPOSITIONS FOR L-DOPA MICROBIOME THERAPY
| US 20240016859 | Kanthasamy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anumantha G. Kanthasamy (Ames, Iowa); Gregory Phillips (Ames, Iowa); Ahmed Abdalla (Ames, Iowa); Nicholas John Backes (Ames, Iowa); Piyush Padhi (Ames, Iowa) |
| ABSTRACT | The present invention generally provides methods and compositions for the treatment of Parkinson's disease, Alzheimer's disease, depression, anxiety, and memory deficits. The invention relates to recombinant microorganisms, particularly gut-colonizing probiotics, modified to produce L-DOPA as well as microcapsules and lyophilized formulations comprising the same. |
| FILED | Thursday, August 24, 2023 |
| APPL NO | 18/455205 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/19 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016865 | Thorne et al. |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH STSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH STSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Stephen Howard Thorne (Pittsburgh, Pennsylvania); Daniel J. Byrd (Pittsburgh, Pennsylvania) |
| ABSTRACT | This disclosure relates to modified viruses, e.g., oncolytic vaccinia viruses, which have been modified to contain an exogenous nucleic acid that expresses a protein that modulates STAT3 activity. It is based, at least in part, on the discovery that vaccinia viruses modified to contain nucleic acid encoding PIAS3 and that express PIAS3 or a fragment thereof can inhibit STAT3 activity and enhance the anti-cancer activity of the vaccinia virus. Accordingly, this disclosure provides for oncolytic vaccinia viruses and methods of using them in the treatment of cancers. |
| FILED | Friday, August 18, 2023 |
| APPL NO | 18/452307 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/768 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/07 (20130101) C07K 14/16 (20130101) C07K 14/4702 (20130101) C07K 16/2827 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/104 (20130101) C12N 15/625 (20130101) C12N 2710/24132 (20130101) C12N 2710/24143 (20130101) Enzymes C12Y 301/03048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016889 | MONANI et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Umrao MONANI (Oradell, New Jersey); Jeong KI-KIM (Fort Lee, New Jersey) |
| ABSTRACT | The present disclosure provides compositions and methods of treating motor neuron diseases, including spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS). A modulator of a heat shock protein, such as an Hsp70 family member protein, may be used in the present method. Alternatively, a mutant heat shock protein may be used. |
| FILED | Friday, September 22, 2023 |
| APPL NO | 18/472574 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 35/761 (20130101) A61K 38/465 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016903 | Hinderer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Christian Hinderer (Baltimore, Maryland); James M. Wilson (Philadelphia, Pennsylvania) |
| ABSTRACT | A co-therapeutic regimen comprising AAV9-mediated intrathecal/intracisternal and/or systemic delivery of an expression cassette containing a hIDS gene and two or more immunosuppressants is provided herein. Also provided are methods and kits containing these vectors and compositions useful for treating Hunter syndrome and the symptoms associated with Hunter syndrome. |
| FILED | Thursday, August 17, 2023 |
| APPL NO | 18/451665 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 35/76 (20130101) A61K 38/465 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 301/06013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016918 | ANOSOVA et al. |
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| FUNDED BY |
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| APPLICANT(S) | SANOFI PASTEUR INC. (Swiftwater, Pennsylvania) |
| ASSIGNEE(S) | SANOFI PASTEUR INC. (Swiftwater, Pennsylvania) |
| INVENTOR(S) | Natalie ANOSOVA (Lexington, Massachusetts); Salvador Fernando AUSAR (Markham, Canada); Catherine BERRY (Lyon, France); Florence BOUDET (Lyon, France); Danilo CASIMIRO (Harleysville, Pennsylvania); Roman M. CHICZ (Belmont, Massachusetts); Gustavo DAYAN (Bethlehem, Pennsylvania); Guy DE BRUYN (Bushkill Township, Pennsylvania); Carlos DIAZGRANADOS (Wind Gap, Pennsylvania); Tong-Ming FU (Philadelphia, Pennsylvania); Marie GARINOT (Lyon, France); Lorry GRADY (Simsbury, Connecticut); Sanjay GURUNATHAN (Bethlehem, Pennsylvania); Kirill KALNIN (Pelham, New Hampshire); Nikolai KHRAMTSOV (Branford, Connecticut); Valérie LECOUTURIER (Chazay d'Azergues, France); Nausheen RAHMAN (Noth York, Canada); Sophie RUIZ (Lyon, France); Stephen SAVARINO (Saylorsburg, Pennsylvania); Saranya SRIDHAR (London, United Kingdom); Indresh K. SRIVASTAVA (Marlborough, Connecticut); James TARTAGLIA (Nazareth, Pennsylvania); Timothy TIBBITTS (East Greenwich, Rhode Island) |
| ABSTRACT | Provided are novel vaccines for prophylactic treatment of SARS-CoV-2 infections and COVID-19 and methods of making the vaccines. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 18/042626 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Original (OR) Class A61K 2039/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016922 | FRIEDMAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Harvey FRIEDMAN (Merion, Pennsylvania); Sita AWASTHI (Bala Cynwyd, Pennsylvania); Gary Cohen (Havertown, Pennsylvania); Drew WEISSMAN (Wynnewood, Pennsylvania) |
| ABSTRACT | The present disclosure provides compositions for the prevention and treatment of genital herpes, comprising nucleoside-modified RNAs that encode herpes simplex virus (HSV) glycoproteins, including those involved in virus entry and immune evasion, and methods of use thereof. |
| FILED | Thursday, August 03, 2023 |
| APPL NO | 18/365166 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/245 (20130101) Original (OR) Class A61K 2039/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/22 (20180101) Peptides C07K 14/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016923 | Pierce et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian G. Pierce (Gaithersburg, Maryland); Thomas R. Fuerst (Gaithersburg, Maryland); Eric A. Toth (Spring Grove, Pennsylvania); Johnathan D. Guest (St. Louis, Missouri); Steven K.H. Foung (Stanford, California); Zhen-Yong Keck (Redwood City, California) |
| ABSTRACT | Disclosed are modified hepatitis C virus (HCV) E1E2 glycoproteins. Disclosed are Disclosed are modified HCV E1E2 glycoproteins comprising a HCV E1 polypeptide; a first scaffold element; a HCV E2 polypeptide; and a second scaffold element, wherein the HCV E1 polypeptide does not comprise a transmembrane domain, and wherein the HCV E2 polypeptide does not comprise a transmembrane domain. Disclosed are modified HCV E1E2 glycoproteins comprising a HCV E1 polypeptide; a first scaffold element; a modified HCV E2 polypeptide; and a second scaffold element, wherein the HCV E1 polypeptide does not comprise a transmembrane domain; a first scaffold element, wherein the modified HCV E2 polypeptide does not comprise a transmembrane domain, wherein the modified HCV E2 polypeptide comprises an antigenic domain D, and wherein the modified HCV E2 polypeptide comprises one or more amino acid alterations in the antigenic domain D and/or wherein the modified HCV E2 polypeptide comprises an antigenic domain A, wherein the antigenic domain A comprises an N-glycan sequon substitution. Also disclosed are methods of using the disclosed modified HCV E1E2 glycoproteins, such as methods of inducing an immune response in a subject, methods of treating a subject, and methods of increasing antigenicity of a HCV E1E2 glycoprotein. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 18/252800 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/29 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/1833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016940 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women`s Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jinjun Shi (Boston, Massachusetts); Yuling Xiao (Brookline, Massachusetts) |
| ABSTRACT | Described herein are novel compositions comprising lipid-poly(ethylene glycol) (lipid-PEG) molecules or lipid-PEG like molecules, and methods of use thereof, e.g., for sustained delivery of therapeutic agents such as nucleic acids, proteins, and small molecules. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 18/038392 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/543 (20170801) Original (OR) Class A61K 47/6937 (20170801) A61K 48/005 (20130101) A61K 48/0041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016943 | MOELLERING et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Raymond E. MOELLERING (Chicago, Illinois); Thomas E. Speltz (Chicago, Illinois); Sean SHANGGUAN (Chicago, Illinois) |
| ABSTRACT | In aspects, the invention provides a polypeptide construct comprising (a) a first polypeptide comprising an amino acid sequence derived from a basic helix of a transcription factor protein that comprises a basic helix-loop-helix domain; and (b) a second polypeptide comprising an amino acid sequence derived from a helix that extends in the C-terminal direction from the end of the loop of a basic helix-loop-helix domain of a transcription factor protein that comprises a basic helix-loop-helix domain; wherein the first polypeptide and the second polypeptide are linked through an interpolypeptide covalent linkage. Additional aspects of the invention are as described herein. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 18/038633 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) Original (OR) Class A61K 47/545 (20170801) Peptides C07K 7/08 (20130101) C07K 14/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016955 | Corey et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David P. Corey (Cambridge, Massachusetts); Eric M. Mulhall (Cambridge, Massachusetts); Maryna V. Ivanchenko (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure, at least in part, provides a dual-AAV vector system and compositions thereof for expression full-length PCDH15 in target cells. The present disclosure also provides the method of using the dual rAAV system for delivering full-length PCDH15 to a target cell (e.g., inner cells or cells in the eye) for treating deafness and/or blindness (e.g., Usher syndrome 1F). |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 18/025719 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/0041 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) A61P 27/16 (20180101) Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) C12N 2800/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016957 | Campbell |
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| FUNDED BY |
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| APPLICANT(S) | Institute for Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Institute for Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kerry S. Campbell (Wyncote, Pennsylvania) |
| ABSTRACT | The invention provides a natural killer cell, NK-92, modified to express an Fc receptor on the surface of the cell, such as CD16 (FcγRIII-A), or other Fcγ or Fr receptors. The modified NK-92 cell can be further modified to concurrently express an associated accessory signaling protein, such as FcεRI-γ, TCR-ζ, or to concurrently express interleukin-2 (IL-2) or other cytokines. Additional methods are disclosed for various assays, assessments, and therapeutic treatments with the modified NK-92 cells. |
| FILED | Tuesday, July 25, 2023 |
| APPL NO | 18/358738 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/39533 (20130101) A61K 39/39558 (20130101) A61K 49/00 (20130101) Original (OR) Class A61K 2035/124 (20130101) Peptides C07K 14/70535 (20130101) C07K 16/28 (20130101) C07K 16/32 (20130101) C07K 16/283 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016972 | Freedman et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin Ross Freedman (Brookline, Massachusetts); David J. Mooney (Sudbury, Massachusetts) |
| ABSTRACT | Described herein are tough gel compositions that comprise an interpenetrating networks (IPN) hydrogel. The IPN hydrogel comprises a first polymer network (covalently crosslinked) and a second polymer network (ionically crosslinked), at least one therapeutic agent, and a clay material. The tough gel compositions may further include an adhesive polymer layer attached to the IPN hydrogel. Methods of use of these compositions, such as for extended release drug delivery, are also described. |
| FILED | Friday, September 18, 2020 |
| APPL NO | 17/761193 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/02 (20130101) A61L 24/0015 (20130101) A61L 24/0031 (20130101) A61L 24/0089 (20130101) Original (OR) Class A61L 2300/222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016979 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Song Li (Beverly Hills, California); Randall J. Lee (Hillsborough, California); Jeff Henry (Los Angeles, California) |
| ABSTRACT | A novel injectable human amniotic membrane (hAM) matrix to enhance cardiac repair and/or regeneration following myocardial injury (MI) and wound healing has been developed. The invention disclosed herein provides human amniotic membranes isolated from human placenta and engineered to be a thermo-responsible, injectable gel at temperature ranges that fall within body temperature. The ultrasound-guided injection of hAM matrix into a rodent model of myocardial infarction significantly improved cardiac contractility, as measured by ejection fraction (EF), and decreased fibrosis. The disclosure provided herein demonstrates the specific engineering injectable hAM matrices and their efficacy in attenuating degenerative changes in cardiac function following MI, which has broad applications in wound healing and tissue regeneration. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 18/255307 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/367 (20130101) A61L 27/3604 (20130101) Original (OR) Class A61L 27/3687 (20130101) A61L 27/3691 (20130101) A61L 2300/41 (20130101) A61L 2400/06 (20130101) A61L 2430/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017097 | CHALASANI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Salk Institute for Biological Studies (La Jolla, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Sreekanth H. CHALASANI (La Jolla, California); Stuart IBSEN (La Jolla, California) |
| ABSTRACT | The invention provides compositions featuring TRP-4 polypeptides and polynucleotides, methods for expressing such polypeptides and polynucleotides in a cell type of interest, and methods for inducing the activation of the TRP-4 polypeptide in neurons and other cell types using ultrasound. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/459143 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 41/0028 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 2007/0026 (20130101) A61N 2007/0039 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 2800/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018064 | Wolf et al. |
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| FUNDED BY |
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| APPLICANT(S) | Pluton Biosciences, Inc (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin M. Wolf (St. Louis, Missouri); Ann M. Guggisberg (St. Louis, Missouri); Boahemaa Adu-Oppong (St. Louis, Missouri); Steven C. Slater (Bainbridge Island, Washington); Barry S. Goldman (St. Louis, Missouri); Alexa Jewell Wagner (St. Louis, Missouri); Nicholas Thomas Norman (St. Charles, Missouri) |
| ABSTRACT | Provided herein is technology relating to functional microbial consortia and particularly, but not exclusively, to methods and systems for producing a microbial consortium possessing a desired function and microbial consortia produced according to such methods. The microbial consortia may be used to improve soil, e.g., for agricultural uses. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/186931 |
| CURRENT CPC | Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/02 (20130101) C05F 11/08 (20130101) Original (OR) Class C05F 17/20 (20200101) C05F 17/30 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018089 | Shulman et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gerald I. Shulman (East Haven, Connecticut); David A. Spiegel (New Haven, Connecticut) |
| ABSTRACT | The present invention includes DNP derivatives that are useful for preventing or treating a metabolic disease or disorder in a subject in need thereof. In certain embodiments, the subject is further administered at least one additional therapeutic agent. |
| FILED | Wednesday, January 11, 2023 |
| APPL NO | 18/153160 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/085 (20130101) Acyclic or Carbocyclic Compounds C07C 205/37 (20130101) Original (OR) Class Steroids C07J 41/0055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018121 | BAUGH et al. |
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| FUNDED BY |
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| APPLICANT(S) | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (Doylestown, Pennsylvania) |
| ASSIGNEE(S) | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (Doylestown, Pennsylvania) |
| INVENTOR(S) | Simon David Peter BAUGH (Ringoes, New Jersey); Kathryn B. FREEMAN (Yardley, Pennsylvania); Jeffrey Claude PELLETIER (Lafayette Hill, Pennsylvania); Allen B. REITZ (Lansdale, Pennsylvania); Richard W. SCOTT (Chadds Ford, Pennsylvania); Garry Robert SMITH (Elverson, Pennsylvania); Sandeep THANNA (Lansdale, Pennsylvania); Damian G. WEAVER (Lansdale, Pennsylvania); David B. WHITMAN (Phoenixville, Pennsylvania) |
| ABSTRACT | Pharmaceutical compositions include heteroaromatic compounds having a disease-modifying action in the treatment of fungal infections and diseases associated with fungal infection. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 18/008399 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 47/44 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 3/00 (20210801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) Heterocyclic Compounds C07D 231/12 (20130101) C07D 249/08 (20130101) C07D 271/107 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 403/14 (20130101) C07D 413/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018169 | Pyle et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anna Marie Pyle (New Haven, Connecticut); Olga Fedorova (New Haven, Connecticut); Erik Jagdmann (New Haven, Connecticut); Michael Van Zandt (New Haven, Connecticut); Lin Yuan (New Haven, Connecticut); Albert DeBerardinis (New Haven, Connecticut) |
| ABSTRACT | The present invention provides compositions and methods for inhibiting group II intron splicing for treating or preventing a disease or disorder associated with an organism harboring an active group II intron. The present invention also provides compositions and methods for inhibiting group II intron splicing for inhibiting, preventing or reducing growth of an organism harboring an active group II intron. |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/456819 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 31/10 (20180101) Acyclic or Carbocyclic Compounds C07C 243/38 (20130101) Original (OR) Class Heterocyclic Compounds C07D 213/30 (20130101) C07D 239/26 (20130101) C07D 307/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018177 | Choe et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); Boyce Thompson Institute for plant Research (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrea Choe (Pasadena, California); Paul W. Sternberg (San Marino, California); Frank C. Schroeder (Ithaca, New York); Stephan H. von Reuss (Jena, Germany) |
| ABSTRACT | The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating an immune and inflammatory disorders disorder by administering a composition comprising a therapeutically effective dosage of an ascaroside compound, or a mixture of ascaroside compounds, or a mixture containing at least one ascaroside. |
| FILED | Monday, June 12, 2023 |
| APPL NO | 18/208629 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/36 (20130101) A01N 43/16 (20130101) A01N 43/38 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) A61K 31/7028 (20130101) Heterocyclic Compounds C07D 309/10 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/04 (20130101) Original (OR) Class C07H 15/08 (20130101) C07H 15/10 (20130101) C07H 15/18 (20130101) C07H 15/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018191 | Baric et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ralph S. Baric (Haw River, North Carolina); David R. Martinez (Durham, North Carolina) |
| ABSTRACT | This invention relates to chimeric coronavirus S proteins and methods of their use, for example, to treat and/or prevent diseases or disorders caused by infection by a coronavirus. |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 18/250559 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/20022 (20130101) C12N 2770/20023 (20130101) C12N 2770/20034 (20130101) C12N 2770/36123 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018193 | Kwong et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United State of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter D. Kwong (Washington, District of Columbia); Barney S. Graham (Smyrna, Georgia); Jason S. McLellan (Austin, Texas); Jeffrey Boyington (Clarksburg, Maryland); Lei Chen (Rockville, Maryland); Man Chen (Clarksburg, Maryland); Gwo-Yu Chuang (Rockville, Maryland); Ivelin Stefanov Georgiev (Nashville, Tennessee); Jason Gorman (Silver Spring, Maryland); Michael Gordon Joyce (Washington, District of Columbia); Masaru Kanekiyo (North Bethesda, Maryland); Gilad Ofek (Gaithersburg, Maryland); Marie Pancera (Seattle, Washington); Mallika Sastry (Rockville, Maryland); Cinque Soto (Rockville, Maryland); Sanjay Srivatsan (Lilburn, Georgia); Guillaume Stewart-Jones (Cambridge, Massachusetts); Yongping Yang (Potomac, Maryland); Baoshan Zhang (Bethesda, Maryland); Tongqing Zhou (Boyds, Maryland) |
| ABSTRACT | Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject. |
| FILED | Monday, September 11, 2023 |
| APPL NO | 18/464786 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/155 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018199 | COHEN et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Pinchas COHEN (Los Angeles, California); Kelvin YEN (Los Angeles, California) |
| ABSTRACT | Described herein is a novel, mitochondrial encoded, open reading frame, that leads to the production of a new mitochondrial peptide. Residing within the ND-Two subunit, a specific small nucleotide polymorphism disrupts expression of this mitochondrial peptide, and is correlated with an increase in obesity and diabetes, particularly in certain ethnic populations. In vitro administration of the peptide increases insulin secretion, decreases fat accumulation and improves glucose uptake in muscle cell. Antibodies generated against the peptide can be used for detecting peptide deficiency, in addition to SNP detection, supporting diagnostic approaches. In vivo studies further revealed that administration of the peptide improves glucose tolerance, thereby providing a new therapeutic avenue for a novel diabetes therapy and decreases bodyweight, thus serving as a novel obesity therapy. Generation of synthetic analogs further enhance or abrogated activity relative to the natural peptide. |
| FILED | Tuesday, August 01, 2023 |
| APPL NO | 18/363178 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) Peptides C07K 7/08 (20130101) C07K 14/47 (20130101) Original (OR) Class C07K 14/435 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/04 (20130101) G01N 2800/042 (20130101) G01N 2800/044 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018210 | Love et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul E. Love (Olney, Maryland); Guillaume Gaud (Bethesda, Maryland); Christian S. Hinrichs (Princeton, New Jersey); John S. Davies (Bethesda, Maryland) |
| ABSTRACT | Disclosed is a cell expressing a modified CD3 subunit chain or a cell expressing a modified non-CD3 subunit chain comprising one or more of: (a) at least one Immuno-receptor Tyrosine-based Activation Motif (ITAM) deletion; or (b) at least one exogenous intracellular hematopoietic cell signaling domain; and (c) at least one modified ITAM comprising an amino acid sequence of Formula I. Related populations of cells, pharmaceutical compositions, methods of making the cells, methods of treating or preventing a condition in a subject, and methods of enhancing an antigen-specific immune response in a subject are also disclosed. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 18/036112 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) A61K 39/4631 (20230501) A61K 39/4632 (20230501) A61K 2239/22 (20230501) Peptides C07K 14/7051 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018216 | KOIDE et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Shohei KOIDE (Chicago, Illinois); Shun-Ichi TANAKA (Chicago, Illinois); Akiko KOIDE (Chicago, Illinois) |
| ABSTRACT | The current application describes various compositions and methods for the production of FN3-based binding proteins with improved stability properties. Aspects of the disclosure relate to polypeptides comprising a variant fibronectin type III (FN3) domain from Sulfolobus tokodaii or Pyrococcus horikoshii comprising one or more amino acid substitutions or insertions in a loop region of FN3, in a non-loop region of FN3, or in both. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/312100 |
| CURRENT CPC | Peptides C07K 14/78 (20130101) Original (OR) Class Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018217 | Smith |
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| FUNDED BY |
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| APPLICANT(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenneth Smith (Norman, Oklahoma) |
| ABSTRACT | The present invention includes antibodies and antigen-binding fragments thereof that specifically bind a SARS-CoV-2 antigen and are in certain embodiments capable of neutralizing a SARS-CoV-2 infection. Polynucleotides encoding an antibody or an antigen-binding fragment, vectors and host cells that comprise a polynucleotide and pharmaceutical compositions are also included in this invention. Also described herein are methods of using the presently disclosed antibodies, antigen-binding fragments, polynucleotides, vectors, host cells, and compositions to diagnose, prevent or treat a SARS-CoV-2 infection. |
| FILED | Thursday, June 29, 2023 |
| APPL NO | 18/344680 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 47/6911 (20170801) A61K 47/6929 (20170801) A61K 49/0058 (20130101) A61K 51/1006 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/1003 (20230801) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) G01N 2469/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018227 | Cao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xu Cao (Baltimore, Maryland) |
| ABSTRACT | In Provided herein are compositions and methods directed to treating, delaying progression of, or ameliorating symptoms related to disorders characterized with TGF-β activity (e.g., disorders characterized with aberrant cartilage formation and/or osteoclast resorption (e.g., ankylosing spondylitis)) (e.g., spinal cord injuries) (e.g., fibrotic scar formation following spinal cord injury) through inhibition of TGF-β activity (e.g., thereby hindering and/or inhibiting aberrant cartilage formation and/or osteoclast resorption within joints, muscles, tendons, ligaments, connective tissue, and/or bones experiencing or at risk of experiencing ankylosis) (e.g., thereby inhibiting fibrotic scar formation following spinal cord injury). |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 18/033746 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/04 (20180101) A61P 25/00 (20180101) Peptides C07K 16/22 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018230 | KANNEGANTI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thirumala-Devi KANNEGANTI (Memphis, Tennessee); Rajendra KARKI (Memphis, Tennessee) |
| ABSTRACT | Methods for treating or mitigating COVID-19, sepsis or hemophagocytic lymphohistiocystosis or cytokine storm-associated syndromes; and treating or preventing inflammatory cell death associated with an inflammatory condition or infection such as SARS-CoV-2, or inducing inflammatory cell death in the context of cancer are provided, which includes the modulation of TNF and/or IFN-γ activity. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 18/245257 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Peptides C07K 16/241 (20130101) Original (OR) Class C07K 16/249 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018242 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children`s Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yang Shi (Newton, Massachusetts); Wanqiang Sheng (Allston, Massachusetts); Arlene H. Sharpe (Brookline, Massachusetts); Martin W. LaFleur (Boston, Massachusetts) |
| ABSTRACT | Provided herein are methods of treating cancer using LSD1 inhibitors in combination with immunotherapy. |
| FILED | Wednesday, May 17, 2023 |
| APPL NO | 18/198404 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) Original (OR) Class C07K 16/2827 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018247 | Tomlinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MUSC Foundation for Research Development (Charleston, South Carolina); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Universitat De Barcelona (Barcelona, Spain) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Tomlinson (Charleston, South Carolina); Ali Alawieh (Atlanta, Georgia); Pablo Engel (Barcelona, Spain) |
| ABSTRACT | The present invention describes compositions and methods for targeting complement inhibition to sites of p-selectin expression, and compositions for inhibiting p-selectin and complement. |
| FILED | Wednesday, August 30, 2023 |
| APPL NO | 18/458214 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Peptides C07K 14/70596 (20130101) C07K 16/2854 (20130101) Original (OR) Class C07K 2317/565 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018263 | Zorniak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Zorniak (San Diego, California); Paul A. Clark (Madison, Wisconsin); Yongku Peter Cho (Storrs, Connecticut); Benjamin J. Umlauf (Madison, Wisconsin); Eric V. Shusta (Madison, Wisconsin); John Shu-Shin Kuo (Austin, Texas) |
| ABSTRACT | The present invention provides antibodies that target glioblastoma stem-like cells and methods and kits for their use. |
| FILED | Thursday, September 07, 2023 |
| APPL NO | 18/463154 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0058 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/3053 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018270 | Meyer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Kathryn Meyer (Durham, North Carolina) |
| ABSTRACT | Provided herein are compositions and methods for detection of N6-methyladenosine (m6A) in ribonucleic acid (RNA). The provided compositions include fusion proteins that can be used to edit RNA and detect m6A residues. Also provided are nucleic acids, vectors, constructs, host cells, and transgenic animals that encode or express such fusions proteins. |
| FILED | Friday, May 05, 2023 |
| APPL NO | 18/313048 |
| CURRENT CPC | Peptides C07K 16/44 (20130101) Original (OR) Class C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/78 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6876 (20130101) C12Q 2600/154 (20130101) Enzymes C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018470 | Kostiuk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Valentyna Kostiuk (New Haven, Connecticut); Mustafa Khokha (New Haven, Connecticut) |
| ABSTRACT | Described herein is a method of maintaining pluripotency in a cell. The method includes in one aspect reducing a membrane potential of the cell. Also described herein is a culture medium for performing certain aspects of the method, as well as a composition in which the pluripotency of a cell is maintained by the culture medium. |
| FILED | Wednesday, July 12, 2023 |
| APPL NO | 18/350978 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) Original (OR) Class C12N 2500/12 (20130101) C12N 2501/998 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018471 | CHOU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania); NEW YORK BLOOD CENTER, INC. (New York, New York) |
| ASSIGNEE(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania); NEW YORK BLOOD CENTER, INC. (New York, New York) |
| INVENTOR(S) | Stella CHOU (Bryn Mawr, Pennsylvania); Connie WESTHOFF (New York, New York) |
| ABSTRACT | Provided herein are engineered red blood cells expressing rare blood antigen group profiles, and methods of making use the same, are described. Also provided are recombinant reagent red blood cells that express or lack the expression of at least one protein (e.g., a blood group antigen) on its surface and uses thereof. |
| FILED | Tuesday, June 06, 2023 |
| APPL NO | 18/330167 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2510/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/80 (20130101) G01N 33/6854 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018479 | Emerson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles P. Emerson (Lyndon, Vermont); Dongsheng Guo (Shrewsbury, Massachusetts); Katelyn M. Daman (Stow, Massachusetts); Jing Yan (Shrewsbury, Massachusetts); Jennifer Chee-Jen Chen (Kingston, Canada); Meng-jiao Shi (Shrewsbury, Massachusetts); Oliver D. King (Somerville, Massachusetts); Lawrence J. Hayward (Sterling, Massachusetts) |
| ABSTRACT | Human skeletal muscle stem cells were generated from facioscapulohumeral muscular dystrophy (FSHD) and healthy control iPSC using a transgene-free skeletal muscle differentiation protocol and production of stable iMyoblasts. Analyses revealed that FSHD and healthy control iMyoblasts are embryonic-like myogenic cells that undergo myotube differentiation ex vivo by growth factor depletion and are efficiently transplantable into the tibialis anterior (TA) muscles of NSG mice, where human muscle under-goes embryonic-to-adult myosin isoform switching. The DUX4 FSHD disease gene maintains its hypomethylated disease state inFSHD iPSC and iMyoblast, and its expression is upregulated during myotube differentiation and in muscle xenografts. Consequently, these iMyoblasts accurately exhibit the molecular pathology of human muscular dystrophies and are useful for the development of drug, gene editing and stem cell therapeutics. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 18/033756 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) Original (OR) Class C12N 2500/02 (20130101) C12N 2501/10 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018485 | KIM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kitai KIM (New York, New York); Maria SKAMAGKI (New York, New York); Yildirim DOGAN (New York, New York) |
| ABSTRACT | Disclosed are findings that: (a) induced pluripotent stem cells derived from aged donors (A-iPSC) show increased genomic instability, a defect in apoptosis, a defect in glucose metabolism, and a blunted DNA damage response are compared to those derived from young donors (Y-iPSC); and (b) inhibition of excessive glutathione-mediated H202 scavenging activity, found to be associated with A-iPSC and in turn inhibiting DNA damage response and apoptosis, substantially rescues these defects and reduces the oncogenic potential of A-iPSC. Supplementation of pluripotency factor ZSCAN 10 (shown to be poorly activated in A-iPSC and to act upstream of glutathione involvement), e.g., by expression as an adjunct to the four Yamanaka iPSC reprogramming factors, led to substantial recovery of genomic stability, DNA damage response, and apoptosis in A-iPSC through enhancing GLUT3 and normalizing homeostasis of glutathione/H202; GLUT3 (a pluripotent stem cell-specific glucose transporter acting upstream of glutathione and also poorly activated in A-iPSC) has similar effects, indicating that inhibition of glutathione/H202 notably through delivery of ZSCAN 10 and/or GLUT3 and/or an exosome subunit will be clinically useful, resulting in A-iPSC of improved properties and reduced oncogenic potential. |
| FILED | Friday, March 10, 2023 |
| APPL NO | 18/182258 |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 15/85 (20130101) C12N 2501/50 (20130101) C12N 2501/71 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2501/998 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018494 | Cox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Benjamin Turitz Cox (Cambridge, Massachusetts); Neena Pyzocha (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting Cas13b effector protein and at least one targeting nucleic acid component like a guide RNA or crRNA. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/349707 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2310/20 (20170501) C12N 2800/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018501 | van der Donk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wilfred A. van der Donk (Urbana, Illinois); Weixin Tang (Somerville, Massachusetts) |
| ABSTRACT | An isolated nucleic acid that includes an open reading frame encoding a lanthipeptide protease polypeptide for scarless tag removal from a polypeptide is presented. Reagents, expression constructs and methods are also provided for preparing a scarless tag polypeptide product from a tagged polypeptide precursor containing a lanthipeptide protease cleavage site. The reagents are directed to novel lanthipeptide proteases and expression constructs and polypeptide precursors that include highly specific lanthipeptide protease substrate recognition sequence. Methods are provided that enable scarless tag removal from a cognate lanthipeptide, a non-cognate lanthipeptide or a heterologous polypeptide that includes extraneous amino acid sequences, such as leader peptides and tags. |
| FILED | Tuesday, November 29, 2022 |
| APPL NO | 18/070554 |
| CURRENT CPC | Peptides C07K 14/31 (20130101) C07K 14/32 (20130101) C07K 14/195 (20130101) C07K 14/315 (20130101) C07K 2319/01 (20130101) C07K 2319/20 (20130101) C07K 2319/21 (20130101) C07K 2319/24 (20130101) C07K 2319/40 (20130101) C07K 2319/50 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) C12P 21/06 (20130101) Enzymes C12Y 304/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018513 | Bradley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FRED HUTCHINSON CANCER CENTER (Seattle, Washington); MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER CENTER (Seattle, Washington); MEMORIAL SLOAN KETTERING CANCER RESEARCH CENTER (New York, New York) |
| INVENTOR(S) | Robert K. Bradley (Seattle, Washington); Omar Abdel-Wahab (New York, New York); Khrystyna North (Seattle, Washington); Salima Benbarche (New York, New York); Bo Liu (New York, New York) |
| ABSTRACT | The disclosure provides artificial nucleic acid introns configured for selective splicing in cells with aberrant RNA splicing activity, e.g., neoplastic cells. The artificial intron can comprise a 5′ splice site, a canonical 3′ splice site, at least one cryptic 3′ splice site, a pyrimidine-rich domain, and at least one branchpoint. Also provided are constructs integrating the artificial introns with exons in a configuration that, when the artificial intron is spliced out by the aberrant RNA splicing factors, encode a functional protein. Also disclosed are methods that employ the disclosed platform of selective expression, including, targeted gene therapy methods (e.g., in cancers), diagnostics and imaging, and drug screening. |
| FILED | Friday, October 22, 2021 |
| APPL NO | 18/249914 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1051 (20130101) C12N 15/1082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018525 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges (Stillwater, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lin Liu (Edmond, Oklahoma); Chaoqun Huang (Stillwater, Oklahoma) |
| ABSTRACT | Compositions containing long non-coding RNAs (lncRNA's) or fragments or variants thereof are disclosed. Also disclosed are compositions containing vectors that include or encode the lncRNA's or fragments/variants thereof. Further disclosed are methods of producing and using these compositions containing or encoding the lncRNA's. |
| FILED | Friday, July 28, 2023 |
| APPL NO | 18/361305 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2320/35 (20130101) C12N 2740/15043 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018542 | Feldman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Feldman (Cambridge, Massachusetts); Avtar Singh (Cambridge, Massachusetts); Paul Blainey (Cambridge, Massachusetts) |
| ABSTRACT | The subject matter disclosed herein is generally directed to methods and compositions for stable transduction of target cells with libraries of genetic elements. The invention reduces intermolecular recombination between library elements and integration of multiple genetic elements. |
| FILED | Monday, December 19, 2022 |
| APPL NO | 18/067900 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2740/15043 (20130101) C12N 2740/15052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018543 | Daigle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Allen Institute (Seattle, Washington) |
| ASSIGNEE(S) | Allen Institute (Seattle, Washington) |
| INVENTOR(S) | Tanya Daigle (Seattle, Washington); Lucas T. Graybuck (Seattle, Washington); Brian Edward Kalmbach (Poulsbo, Washington); Edward Sebastian Lein (Seattle, Washington); John K. Mich (Seattle, Washington); Boaz P. Levi (Seattle, Washington); Adriana Estela Sedeño Cortés (Seattle, Washington); Bosiljka Tasic (Seattle, Washington); Jonathan Ting (Seattle, Washington); Hongkui Zeng (Seattle, Washington) |
| ABSTRACT | Artificial expression constructs for modulating gene expression in targeted central nervous system cell types are described. The artificial expression constructs can be used to express synthetic genes or modify gene expression in chandelier cells. Chandelier cells are a subtype of GABAergic interneurons that that have been implicated in disorders such as epilepsy and schizophrenia. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 18/252498 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018544 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Peter Cabeceiras (Boston, Massachusetts) |
| ABSTRACT | Human-derived virus-like particles (heVLPs), comprising a membrane comprising a phospholipid bilayer with one or more HERV-derived envelope proteins on the external side; one or more HERV-derived GAG proteins in the heVLP core, and a cargo molecule, e.g., a biomolecule and/or chemical cargo molecule, disposed in the core of the heVLP on the inside of the membrane, wherein the heVLP does not comprise a gag protein, except for gag proteins that are encoded in the human genome or gag proteins that are encoded by a consensus sequence that is derived from gag proteins found in the human genome, and methods of use thereof for delivery of the cargo molecule to cells. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/351800 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2740/10023 (20130101) C12N 2740/10042 (20130101) C12N 2740/10052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018552 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridger, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); David Arthur Scott (Cambridge, Massachusetts); Winston Xia Yan (Cambridge, Massachusetts); Sourav Choudhury (Cambridge, Massachusetts); Mattias Heidenreich (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments disclosed herein are directed to engineered CRISPR-Cas effector proteins that comprise at least one modification compared to an unmodified CRISPR-Cas effector protein that enhances binding of the CRISPR complex to the binding site and/or alters editing preference as compared to wild type. In certain example embodiments, the CRISPR-Cas effector protein is a Type V effector protein. In certain other example embodiments, the Type V effector protein is Cpf1. Embodiments disclosed herein are directed to viral vectors for delivery of CRISPR-Cas effector proteins, including Cpf1. In certain example embodiments, the vectors are designed so as to allow packaging of the CRISPR-Cas effector protein within a single vector. There is also an increased interest in the design of compact promoters for packing and thus expressing larger transgenes for targeted delivery and tissue-specificity. Thus, in another aspect certain embodiments disclosed herein are directed to delivery vectors, constructs, and methods of delivering larger genes for systemic delivery. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345935 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 9/5184 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/32 (20130101) C12N 2740/13042 (20130101) C12N 2740/13043 (20130101) C12N 2800/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018569 | Levner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Levner (Boston, Massachusetts); Je-Hyuk Lee (Allston, Massachusetts); George M. Church (Brookline, Massachusetts); Michael Super (Lexington, Massachusetts) |
| ABSTRACT | The inventions provided herein relate to detection reagents, compositions, methods, and kits comprising the detection reagents for use in detection, identification, and/or quantification of analytes in a sample. Such detection reagents and methods described herein allow multiplexing of many more labeled species in the same procedure than conventional methods, in which multiplexing is limited by the number of available and practically usable colors. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/459068 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6804 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) G01N 33/56911 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018591 | Gruen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut); Brock University (St. Catherines, Canada) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut); Brock University (St. Catherines, Canada) |
| INVENTOR(S) | Jeffrey R. Gruen (Hamden, Connecticut); Andrew Adams (New Haven, Connecticut); Dongnhu Truong (Rocky Hill, Connecticut); Jan Frijters (Pelham, Canada); Joan Bosson-Heenan (New Haven, Connecticut) |
| ABSTRACT | Disclosed herein are kits and methods for assessing the risk of poor reading performance in an individual by detecting and identifying single nucleotide polymorphisms in chromosome 19, e.g. in the KIAA0355 (GARRE1) gene. Also disclosed herein are risk alleles in chromosome 19 that are associated with a latent measure for reading ability. |
| FILED | Thursday, October 08, 2020 |
| APPL NO | 17/766957 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018597 | Perou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles M. Perou (Chapel Hill, North Carolina); Joel S. Parker (Apex, North Carolina); Youli Xia (Chapel Hill, North Carolina); Cheng Fan (Chapel Hill, North Carolina) |
| ABSTRACT | The present disclosure provides a method for generating a calculated cancer signature for a cancer-related phenotype based on copy number alterations (CNAs) in a patient sample. The calculated cancer signature may correspond to a somatic mutation, an mRNA expression signature, or a protein expression signature. The disclosure also provides a method treating a patient using the calculated cancer phenotype. In addition, the disclosure provides a method for generating a calculated signature based on CNAs to replicate a cancer phenotype. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/768059 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/10 (20190201) G16B 25/10 (20190201) G16B 40/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/00 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018650 | Miao |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Houxun Miao (Zionsville, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Houxun Miao (Zionsville, Indiana) |
| ABSTRACT | Disclosed herein is a method to produce hard x-ray phase gratings for x-ray multi-contrast imaging. The method is based on the conformal atomic layer deposition (ALD) of material with high x-ray refractive index decrement δ. The method is particularly suitable for submicron period x-ray phase grating fabrication. The fabrication process to produce x-ray phase gratings in this disclosure is compatible with standard semiconductor fabrication instrument and suitable for mass production. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/812872 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/34 (20130101) C23C 16/402 (20130101) C23C 16/403 (20130101) C23C 16/45529 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019353 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiao Wang (Cambridge, Massachusetts); Jia Liu (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed herein are methods and systems for correlating continuous physiological processes (e.g., electrophysiological activity) and biomolecular processes (e.g., gene expression) in cells within a tissue. Also disclosed herein are methods for preparing a tissue for continuous electrophysiological recording. Further disclosed herein are systems comprising nanoelectronic devices within cells in a tissue, wherein each nanoelectronic device comprises a unique electronic barcode. The methods and systems described herein comprise any tissue with electrical activity (e.g., brain tissue, heart tissue, nervous system tissue, muscle tissue, pancreas tissue, or gastrointestinal tract tissue). Additionally disclosed herein are methods for disease modeling, methods for discovering a target for treating a disease, and methods for drug screening. |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 18/033754 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1031 (20130101) Original (OR) Class G01N 27/3278 (20130101) G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019387 | Stoodley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Stoodley (Columbus, Ohio); Rafael Bruschweiler (Columbus, Ohio); Abigail Leggett (Columbus, Ohio) |
| ABSTRACT | The present disclosure relates to methods of identifying and detecting metabolites in joint fluid to treat and/or prevent a joint infection. The present disclosure also relates to method of preventing a bacterial biofilm accumulation and treating a joint infection using NMR-based metabolomics. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/350477 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/132 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/082 (20130101) Original (OR) Class G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019398 | Litvinov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Dmitri Litvinov (Friendswood, Texas); Long Chang (Pearland, Texas); Richard Willson (Houston, Texas) |
| ABSTRACT | A biosensor may provide a magnetoresistive (MR) film comprising a nonmagnetic layer may be sandwiched between the two ferromagnetic layers. The MR film may be positioned on a substrate, where the edges of the MR film are in contact with leads. The leads may be in contact with pads. The sensors may provide quasi-digital readout that enable greatly enhanced sensitivity. In some embodiments, biosensors may be arranged as array of sensors. The array of sensors may be arranged as a symmetric or asymmetric N1×N2 array, where N1 and N2 are integers, N1 represents the number of sensors linked together in series, and N2 represents the number of sensor sets in parallel, where each sensor set may comprise one or more sensors. Further, the array of sensors may be coupled to a voltmeter, which may be a single voltmeter in that allows the sensors to all be probed simultaneously. |
| FILED | Monday, September 25, 2023 |
| APPL NO | 18/372558 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/745 (20130101) Original (OR) Class G01N 33/54326 (20130101) G01N 33/54346 (20130101) G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019429 | WANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Shaopeng WANG (Chandler, Arizona); Guangzhong MA (Tempe, Arizona); Xiaoyan ZHOU (Tempe, Arizona) |
| ABSTRACT | Provided herein are methods of determining binding kinetics of a ligand. In some embodiments, the methods include contacting the ligand with a first surface of a substrate, which first surface comprises an electrically conductive coating and a population of receptors connected to the first surface via one or more linker moieties, wherein the receptors bind, or are capable of binding, to the ligand, applying an alternating current electric field to the substrate to induce the receptors to oscillate proximal to the first surface of the substrate, and detecting changes in oscillation amplitudes of the receptors over a duration. Related receptor oscillator array devices, systems and computer readable media are also provided. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/349650 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/553 (20130101) G01N 33/557 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019439 | Condeelis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John S. Condeelis (Bronx, New York); Maja Oktay (Rye, New York) |
| ABSTRACT | Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using Tie-2 inhibitors. Methods of reducing chemotherapy-induced metastasis, or chemotherapy-induced cancer cell dissemination, for patients subject to chemotherapy using inhibitors of Mena expression and/or function are also provided. |
| FILED | Wednesday, September 13, 2023 |
| APPL NO | 18/466595 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) G01N 33/57415 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019442 | Colson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brett Colson (Tucson, Arizona); Rhye-Samuel Kanassatega (Tucson, Arizona) |
| ABSTRACT | Cardiac Myosin Binding Protein-C (MyBP-C) is a thick filament-associated protein of the sarcomere and a potential therapeutic target for treating heart failure. The present invention utilizes the MyBP-C N-terminal domains C0 through C2 (C0-C2) to create a fluorescent protein biosensor suitable for time-resolved fluorescence energy transfer (TR-FRET). The dynamic range and precision of the phosphorylation-mediated changes of the fluorescent protein biosensor demonstrate excellent assay functionality for the purposes of high-throughput screening and enabling scientific discovery for understanding MyBP-C in health and disease. These findings provide new molecular insight into the regulatory role of MyBP-C in contractility and demonstrate the potential of C0-C2 biosensors for structure-based screening of compounds in search of MyBP-C-targeted therapies for heart failure. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 18/044344 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) Original (OR) Class G01N 2333/4712 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019562 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhongtao Hu (St. Louis, Missouri); Hong Chen (St. Louis, Missouri) |
| ABSTRACT | A method of fabricating a binary metasurface for producing an ultrasound Airy beam for underwater ultrasound applications is provided. The method includes generating an amplitude distribution of an Airy beam at a frequency, and converting the amplitude distribution into a binary phase profile. The method also includes generating a 3D printing design of a binary metasurface based on the binary phase profile, wherein the binary metasurface includes ridges and grooves defined by neighboring ridges, a ridge having a thickness corresponding to a phase delay of π/2 of the Airy beam between water and a 3D-printable material. The method further includes additively manufacturing the binary metasurface with the 3D-printable material based on the 3D printing design. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/352700 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/00 (20141201) B33Y 70/00 (20141201) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/524 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020841 | Kheradvar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arash Kheradvar (Irvine, California); Gianni Pedrizzetti (Irvine, California) |
| ABSTRACT | Systems and methods for producing velocity data associated with three-dimensional (3D) flow field images. In some embodiments, the method includes receiving data associated with a plurality of frames of a flow field relating to image data acquired by a medical imaging device, in which the data includes information corresponding to measurements of the flow field over time within a chamber; performing, for each of the plurality of frames, the following operations including: generating, for a respective frame, a data correction based on an interaction of the flow field with the chamber, applying the data correction to a velocity field corresponding to the respective frame, and imposing an incompressibility constraint for the flow field on one or more data points of the respective frame; and generating, subsequent to imposing the incompressibility constraint, a plurality of corrected velocity fields each of which corresponds to one of the plurality of frames. |
| FILED | Wednesday, July 12, 2023 |
| APPL NO | 18/351084 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/06 (20130101) A61B 8/481 (20130101) A61B 8/483 (20130101) A61B 8/0883 (20130101) Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 7/0014 (20130101) Original (OR) Class G06T 7/246 (20170101) G06T 2200/04 (20130101) G06T 2207/10132 (20130101) G06T 2207/20212 (20130101) G06T 2207/30048 (20130101) G06T 2207/30104 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020912 | MOGHARI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mehdi H. MOGHARI (Boston, Massachusetts); Andrew J. POWELL (Boston, Massachusetts); Tal GEVA (Boston, Massachusetts) |
| ABSTRACT | The invention features a prospective respiratory motion compensation technique for cardiovascular magnetic resonance imaging of the whole-heart of a free-breathing subject. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/373232 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0044 (20130101) A61B 5/055 (20130101) A61B 5/113 (20130101) A61B 5/7289 (20130101) Image Data Processing or Generation, in General G06T 15/08 (20130101) Original (OR) Class G06T 2210/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240016830 | Golobish et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CytoSorbents, Inc. (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Golobish (Princeton, New Jersey); Maryann Gruda (Yardley, Pennsylvania); Tamaz Guliashvili (Philadelphia, Pennsylvania); Pamela O'Sullivan (Manalapan, New Jersey); Andrew Scheirer (Hoboken, New Jersey); Vi Dan (East Brunswick, New Jersey); Wei-Tai Young (Hillsborough, New Jersey); Vincent Capponi (Lawrenceville, New Jersey); Phillip Chan (Cherry Hill, New Jersey) |
| ABSTRACT | The invention concerns biocompatible polymer systems comprising at least one polymer with a plurality of pores, said polymer comprising a sulfonic acid salt functionality designed to adsorb a broad range of protein based toxins from less than 0.5 kDa to 1,000 kDa and positively charged ions including but not limited to potassium. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345683 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/795 (20130101) Original (OR) Class A61K 47/20 (20130101) A61K 47/26 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3679 (20130101) A61M 5/165 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/264 (20130101) B01J 20/267 (20130101) B01J 20/28069 (20130101) B01J 39/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016918 | ANOSOVA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SANOFI PASTEUR INC. (Swiftwater, Pennsylvania) |
| ASSIGNEE(S) | SANOFI PASTEUR INC. (Swiftwater, Pennsylvania) |
| INVENTOR(S) | Natalie ANOSOVA (Lexington, Massachusetts); Salvador Fernando AUSAR (Markham, Canada); Catherine BERRY (Lyon, France); Florence BOUDET (Lyon, France); Danilo CASIMIRO (Harleysville, Pennsylvania); Roman M. CHICZ (Belmont, Massachusetts); Gustavo DAYAN (Bethlehem, Pennsylvania); Guy DE BRUYN (Bushkill Township, Pennsylvania); Carlos DIAZGRANADOS (Wind Gap, Pennsylvania); Tong-Ming FU (Philadelphia, Pennsylvania); Marie GARINOT (Lyon, France); Lorry GRADY (Simsbury, Connecticut); Sanjay GURUNATHAN (Bethlehem, Pennsylvania); Kirill KALNIN (Pelham, New Hampshire); Nikolai KHRAMTSOV (Branford, Connecticut); Valérie LECOUTURIER (Chazay d'Azergues, France); Nausheen RAHMAN (Noth York, Canada); Sophie RUIZ (Lyon, France); Stephen SAVARINO (Saylorsburg, Pennsylvania); Saranya SRIDHAR (London, United Kingdom); Indresh K. SRIVASTAVA (Marlborough, Connecticut); James TARTAGLIA (Nazareth, Pennsylvania); Timothy TIBBITTS (East Greenwich, Rhode Island) |
| ABSTRACT | Provided are novel vaccines for prophylactic treatment of SARS-CoV-2 infections and COVID-19 and methods of making the vaccines. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 18/042626 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Original (OR) Class A61K 2039/53 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017214 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michael Jeffrey Anderson (Troy, Michigan); Jeremy Stephen Walker (Oakland, Michigan); James Saye Dusenbury, IV (Novi, Michigan) |
| ABSTRACT | A portable filtration system is described. The system may comprise: a mixing portion, comprising: a pump adaptor and a contaminant regulator. The pump adaptor may comprise: an upper plate, a lower plate, and a screen. The screen may axially extend between the upper and lower plates, wherein the upper plate, the lower plate, and the screen define a channel of a mixing chamber. The contaminant regulator may comprise a through-passage coupled to the upper plate, wherein the through-passage is in fluid communication with the mixing chamber. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/477581 |
| CURRENT CPC | Separation B01D 61/10 (20130101) B01D 61/12 (20130101) B01D 61/025 (20130101) Original (OR) Class B01D 65/02 (20130101) B01D 2311/04 (20130101) B01D 2311/06 (20130101) B01D 2311/246 (20130101) B01D 2311/2649 (20130101) B01D 2313/18 (20130101) B01D 2321/02 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/008 (20130101) C02F 1/441 (20130101) C02F 2209/003 (20130101) C02F 2209/03 (20130101) C02F 2209/10 (20130101) C02F 2301/043 (20130101) C02F 2303/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017276 | McCreary et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Figure, Inc. (Lorton, Virginia) |
| ASSIGNEE(S) | Figure, Inc. (Lorton, Virginia) |
| INVENTOR(S) | Leonard McCreary (Lorton, Virginia); Chris Holtzclaw (Lorton, Virginia); Jonathon McDaniels (Lorton, Virginia) |
| ABSTRACT | Disclosed is a noise suppressor for use inside a nozzle and adjacent a nozzle liner. The suppressor can include an inlet with a cross-sectional area larger than that of the nozzle liner outlet. The suppressor can also have an entrance length with a diverging cross-sectional area, and an exit length extending from the entrance length. By incorporating this geometry, the noise suppressor reduces noise and improves performance of the apparatus in which the suppressor is used. |
| FILED | Wednesday, September 27, 2023 |
| APPL NO | 18/373764 |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/002 (20180801) Original (OR) Class Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017348 | Pagan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| INVENTOR(S) | Michael Barnes Pagan (Knoxville, Tennessee) |
| ABSTRACT | Provided are methods and apparatus for bonding metals. In an example, a provided method includes (i) disposing a layer of Vanadium onto a first Titanium surface of a first tangible object, (ii) placing a second Titanium surface of a second tangible object in direct contact with the layer of Vanadium, and (iii) imparting, using a sonotrode, compressive and shear forces to the first Titanium surface, the layer of Vanadium, and the second Titanium surface, to cause plastic deformation that bonds the first Titanium surface to the second Titanium surface. |
| FILED | Wednesday, May 31, 2023 |
| APPL NO | 18/326310 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/103 (20130101) Original (OR) Class B23K 2103/14 (20180801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017482 | Immer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Darby Immer (Niskayuna, New York); Robert John Filkins (Niskayuna, New York); Victor Petrovich Ostroverkhov (Ballston Lake, New York); Michael Robert Tucker (Niskayuna, New York) |
| ABSTRACT | Methods of additively manufacturing a three-dimensional object include irradiating a first build plane region using a first energy beam, irradiating a second build plane region using a second energy beam, and irradiating an interlace region between the first build plane region and the second build plane region. Irradiating the interlace region comprises directing the first energy beam along a first oscillating path and directing the second energy beam along a second oscillating path intersecting and overlapping with the first oscillating path. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/865493 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/28 (20210101) B22F 12/45 (20210101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) Original (OR) Class B29C 64/268 (20170801) B29C 64/282 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017542 | WILLIAMS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vadient Optics, LLC (Beaverton, Oregon) |
| ASSIGNEE(S) | Vadient Optics, LLC (Beaverton, Oregon) |
| INVENTOR(S) | George WILLIAMS (Vashon, Washington); Paul John HARMON (Albany, Oregon); Charles G. DUPUY (Corvallis, Oregon) |
| ABSTRACT | A method for forming a heterogeneous or gradient dielectric-property element comprises: (a) providing a plurality of solution-based feedstocks, each including an organic matrix, wherein at least one of the feedstocks includes a nanoparticle filler dispersed within the organic matrix, the feedstocks comprising a first ink having a first photosensitive entity and one or more additional feedstocks having other photosensitive entities, the first and subsequent feedstocks having at least one different photosensitization absorption band, such that spectrally discrete exposure results in different degrees of curing; (b) providing an electromagnetic (EM) source configured to polymerize one or more of the feedstocks; (c) depositing the feedstocks in a plurality of layers; and (e) curing at least a portion of the plurality of feedstocks, wherein deposition and subsequent curing results in regions where complex dielectric properties are different within or between at least one of the plurality of layers. |
| FILED | Monday, April 03, 2023 |
| APPL NO | 18/194984 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Original (OR) Class B29C 64/264 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0006 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017775 | Hart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Robert James Hart (Bruce Township, Michigan); Andrew Quintin Smail (Shelby Township, Michigan) |
| ABSTRACT | A band track including a band having an inner surface, an outer surface, a first side face, and a second side face; a plurality of teeth extending from the inner surface and spaced apart circumferentially around the inner surface; a plurality of lugs extending from the outer surface and each spaced a distance apart circumferentially around the outer surface; a plurality of living hinges defined within the band circumferentially between each of the plurality of teeth; and at least one fiber-reinforcement disposed circumferentially within a neutral plane of the plurality of living hinges and a method of making the same. |
| FILED | Thursday, September 28, 2023 |
| APPL NO | 18/374002 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 50/02 (20141201) Motor Vehicles; Trailers B62D 55/28 (20130101) B62D 55/244 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017823 | PARSONS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island); Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Thomas Dewey PARSONS (Fort Worth, Texas); Charles Eric COVINGTON (Colleyville, Texas); Kent E. DONALDSON (Fort Worth, Texas); Andrew Thomas CARTER (Richland Hills, Texas) |
| ABSTRACT | In an embodiment, an aircraft includes a drive system, a main engine coupled to the drive system to provide first power, and a supplemental engine coupled to the drive system to provide second power additive to the first power. The aircraft also includes a control system to control the main engine and the supplemental engine to optimize usage of the supplemental engine. The control system is operable to maintain the supplemental engine in a reduced power state at least until a determination is made that supplemental power is needed to satisfy a total power demand of the drive system. The control system is also operable to determine that supplemental power is needed to satisfy the total power demand of the drive system. The control system is further operable to increase a power level of the supplemental engine in response to the determination that supplemental power is needed. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/867231 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/12 (20130101) Original (OR) Class Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 31/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017824 | Orbon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | James Breen Orbon (New Haven, Connecticut); James McCollough (Fort Worth, Texas); Evan S. Tobin (Newtown, Connecticut); Xiaole Xie (Westport, Connecticut); Jonathan Frydman (New Haven, Connecticut) |
| ABSTRACT | A propeller system for a tail section of an aircraft includes a propeller hub located at the tail section of the aircraft, a plurality of propeller blades mounted to and extending outwardly from the propeller hub, a propeller shaft coupled to the propeller hub and operable to rotate the propeller hub about an axis of rotation, and a propeller gearbox connected to the propeller shaft. The propeller gearbox is fluidly cooled by an airflow within the tail section. A spinner assembly surrounds the propeller hub. The spinner assembly includes at least one outlet opening formed therein downstream from the propeller hub relative to the airflow. The spinner assembly is rotatable to draw the airflow into at least one cooling flow inlet formed in the tail section and across the propeller gearbox to cool the propeller gearbox and out the at least one outlet opening. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/373172 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/12 (20130101) B64C 27/46 (20130101) Original (OR) Class B64C 2027/8272 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 13/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018068 | Guerieri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army DEVCOM, Amy Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip M. Guerieri (Catonsville, Maryland); Katherine M. Ferguson (Columbia, Maryland); Erin L. Gawron-Hyla (Alexandria, Virginia) |
| ABSTRACT | A technique for forming an energetic ink is provided. The technique includes forming a non-reactive layer by disposing a composite ink on a substrate, the composite ink including a polymer binder that is solvent-permeable and porous fuel particles (e.g. porous silicon particles). Mixing, printing, casting, assembling, or otherwise handling the inert composite can occur while it remains non-reactive. Subsequently, the technique can then include depositing a liquid solution of solid oxidizer onto the non-reactive layer, which can permeate the binder and impregnate the porous fuel particles with a solid oxidizer, activating the composite ink. In this manner, components with the composite ink can be partially and safely fabricated/assembled while the ink is inert, and the ink can then be activated at a later point in a manufacturing process. |
| FILED | Monday, May 08, 2023 |
| APPL NO | 18/144292 |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 27/00 (20130101) C06B 33/06 (20130101) Original (OR) Class C06B 45/08 (20130101) C06B 45/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018082 | Stevic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Twelve Benefit Corporation (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Luka Stevic (Novi Sad, Serbia); Enrique Cintron (Brooklyn, New York); Lisa Wynia (Hayward, California); Gregory DiCosola (Redmond, Washington); Etosha R. Cave (Berkeley, California); Myron Wayne Wilson, Jr. (Longview, Texas); Matthew Wayne Wilson (Longview, Texas) |
| ABSTRACT | Provided are systems and methods for metal formate synthesis from carbon monoxide supplied by an electrolyzer having a membrane electrode assembly which incorporate the capacity to recover and recycle various chemical components of the production process. For the synthesis, carbon monoxide from an electrolyzer is reacted with a solubilized metal hydroxide in a batch process or a continuous process. |
| FILED | Friday, June 02, 2023 |
| APPL NO | 18/328540 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/10 (20130101) Original (OR) Class Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/23 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018121 | BAUGH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (Doylestown, Pennsylvania) |
| ASSIGNEE(S) | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (Doylestown, Pennsylvania) |
| INVENTOR(S) | Simon David Peter BAUGH (Ringoes, New Jersey); Kathryn B. FREEMAN (Yardley, Pennsylvania); Jeffrey Claude PELLETIER (Lafayette Hill, Pennsylvania); Allen B. REITZ (Lansdale, Pennsylvania); Richard W. SCOTT (Chadds Ford, Pennsylvania); Garry Robert SMITH (Elverson, Pennsylvania); Sandeep THANNA (Lansdale, Pennsylvania); Damian G. WEAVER (Lansdale, Pennsylvania); David B. WHITMAN (Phoenixville, Pennsylvania) |
| ABSTRACT | Pharmaceutical compositions include heteroaromatic compounds having a disease-modifying action in the treatment of fungal infections and diseases associated with fungal infection. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 18/008399 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 47/44 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 3/00 (20210801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) Heterocyclic Compounds C07D 231/12 (20130101) C07D 249/08 (20130101) C07D 271/107 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 403/14 (20130101) C07D 413/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018187 | ALVAREZ |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THERADAPTIVE, INC. (Frederick, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Luis ALVAREZ (Lexington, Massachusetts) |
| ABSTRACT | Provided herein are polypeptides that include one or more β-tricalcium phosphate (βTCP)-binding sequence(s) and uses thereof. |
| FILED | Wednesday, August 16, 2023 |
| APPL NO | 18/451003 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/04 (20130101) A61K 38/16 (20130101) A61K 38/1875 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/00 (20180101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/001 (20130101) C07K 14/51 (20130101) C07K 14/475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018210 | Love et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul E. Love (Olney, Maryland); Guillaume Gaud (Bethesda, Maryland); Christian S. Hinrichs (Princeton, New Jersey); John S. Davies (Bethesda, Maryland) |
| ABSTRACT | Disclosed is a cell expressing a modified CD3 subunit chain or a cell expressing a modified non-CD3 subunit chain comprising one or more of: (a) at least one Immuno-receptor Tyrosine-based Activation Motif (ITAM) deletion; or (b) at least one exogenous intracellular hematopoietic cell signaling domain; and (c) at least one modified ITAM comprising an amino acid sequence of Formula I. Related populations of cells, pharmaceutical compositions, methods of making the cells, methods of treating or preventing a condition in a subject, and methods of enhancing an antigen-specific immune response in a subject are also disclosed. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 18/036112 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) A61K 39/4631 (20230501) A61K 39/4632 (20230501) A61K 2239/22 (20230501) Peptides C07K 14/7051 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018273 | DEMIREL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Melik DEMIREL (State College, Pennsylvania); Mert VURAL (State College, Pennsylvania); Mauricio TERRONES (State College, Pennsylvania); Yu LEI (State College, Pennsylvania); Ibrahim Tarik OZBOLAT (Boalsburg, Pennsylvania) |
| ABSTRACT | Provided are compositions that include at least one two-dimensional layer of an inorganic compound and at least one layer of an organic compound in the form of one or more polypeptides. Methods of making and using the materials are provided. The organic layer contains one or more polypeptides, each of which have alternating repeats of crystallite-forming subsequences and amorphous subsequences. The crystallite-forming subsequences form crystallites comprising stacks of one or more β-sheets. The amorphous subsequences form a network of hydrogen bonds. A method includes i) combining one or more polypeptides with an inorganic material and an organic solvent, and ii) depositing one or more polypeptides, the inorganic material and the organic solvent onto a substrate. These steps can be repeated to provide a composite material that is a multilayer composite material. The composite materials can be used in a wide array of textile, electronic, semi-conducting, and other applications. |
| FILED | Wednesday, July 05, 2023 |
| APPL NO | 18/347061 |
| CURRENT CPC | Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/0011 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Peptides C07K 1/042 (20130101) C07K 17/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018296 | DAI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lenore DAI (Phoenix, Arizona); Aditi CHATTOPADHYAY (Chandler, Arizona); Elizabeth NOFEN (Phoenix, Arizona); Jin ZOU (San Diego, California); Bonsung KOO (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lenore DAI (Phoenix, Arizona); Aditi CHATTOPADHYAY (Chandler, Arizona); Elizabeth NOFEN (Phoenix, Arizona); Jin ZOU (San Diego, California); Bonsung KOO (Tempe, Arizona) |
| ABSTRACT | Compositions including a thermosetting polymer network and a mechanophore covalently bonded to the thermosetting polymer network are provided. Substrates including the compositions are provided. In addition, methods of making the compositions and methods of monitoring stress on a substrate comprising the compositions are provided. |
| FILED | Friday, July 21, 2023 |
| APPL NO | 18/356526 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/1477 (20130101) Original (OR) Class C08G 59/5006 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/20 (20130101) Compositions of Macromolecular Compounds C08L 63/00 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018528 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ross D. Jones (Vancouver, Canada); Yili Qian (Madison, Wisconsin); Domitilla Del Vecchio (Cambridge, Massachusetts); Ron Weiss (Newton, Massachusetts) |
| ABSTRACT | Provided herein are feedback controller circuits and cell state classifiers for tunable phosphorylation-based transcriptional regulation of gene expression in cells based on intracellular miRNA profiles and degradation by small molecules. Also provided are methods of using feedback controller circuits and cell state classifiers for determining the cell state, and methods of treating cells and subjects using feedback controller circuits and cell state classifiers encoding therapeutic output molecules. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 18/039583 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 48/0066 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) C12N 15/635 (20130101) Original (OR) Class C12N 2830/001 (20130101) Enzymes C12Y 207/13003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018581 | Fremont-Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Philip Fremont-Smith (Newmarket, New Hampshire); Chelsea Lynn Lennartz (Hollis, New Hampshire); Natalie Damaso (Woburn, Massachusetts) |
| ABSTRACT | This patent application relates generally to mixture deconvolution systems and methods for identifying DNA profiles. Various embodiments of the present invention concern the deconvolution of unknown DNA profiles in a two-person DNA mixture into two DNA profiles. Deconvolution methods isolate distinct DNA profiles from a DNA mixture without the need to match against DNA reference profiles. Various embodiments include a mixture deconvolution pipeline that involves a series of mathematical steps and machine learning algorithms to achieve the desired performance and decision-support outputs. Various embodiments enable distant familial matching to existing investigative genetic genealogy (IGG; also known as forensic genetic genealogy (FGG)) databases. This capability enables the generation of investigative leads from unresolved casework samples (i.e., DNA mixtures) by identifying possible genealogical relationships to one or more person(s) of interest. Such aspects may be performed in association with one or more systems used for genetic identification. |
| FILED | Monday, May 15, 2023 |
| APPL NO | 18/197641 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/20 (20190201) G16B 30/00 (20190201) G16B 40/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019025 | Mueller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Douglas Robert Mueller (Coppell, Texas); Ivan Russell Laric (Fort Worth, Texas) |
| ABSTRACT | A fluid pump system for an aircraft has a rotatable component having first and second fluid ports, each port in fluid communication with a selected interior portion of the component, the portions being spaced from each other. A valve controls allows a first flow rate through the first fluid port and allows a second flow rate through the second fluid port when the component is in a first angular orientation. The valve allows a third flow rate through the first fluid port and allows a fourth flow rate through the second fluid port when the component is in a second angular orientation. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/812880 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 29/0033 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 35/00 (20130101) Gearing F16H 57/0435 (20130101) Original (OR) Class F16H 57/0436 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019053 | Schoelen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| ASSIGNEE(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| INVENTOR(S) | Mark A. Schoelen (Dallas, Texas); Conan S. St. John (Allen, Texas); David Lewis (Dallas, Texas) |
| ABSTRACT | An assembly includes a first tube including a first flange at one end, wherein the first flange includes a first knife-edge ring defined in an axial face thereof. A second tube includes a second flange at one end, wherein the second flange includes a second knife-edge ring defined in an axial face thereof. A gasket is seated between the first and second flanges. The gasket is in a deformed state conforming to the first and second knife-edge rings to seal a space inside the first and second tubes from an external environment. A nut is included radially outward from the first and second flanges, wherein the nut includes internal threads engaged to compress the first and second flanges toward one another. |
| FILED | Wednesday, June 14, 2023 |
| APPL NO | 18/209826 |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 19/025 (20130101) F16L 19/0218 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019109 | Ross et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | First-Light USA, LLC (Seymour, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeremy B. Ross (Monticello, Illinois); Blake S. Good (Urbana, Illinois); Jacob A. Flagle (New Palestine, Indiana) |
| ABSTRACT | A frame having a clip for securing the frame to an article of clothing or other object. The frame includes a mount for receiving a removable module and a rotatably attached clip. The clip includes an opening for accommodating sewing ribs between portions of a webbing and a gate (which may be a locking wire) moveable between an open position and a closed position at one end of the opening. In the open position, the locking wire removably engages one of a pair of elongated members defining the opening, e.g., by removably engaging that elongated member at a recess in an outside edge thereof, and does not obstruct the opening. When in the closed position, the locking wire removably engages the other of the elongated members, for example by removably engaging that other elongated member at a recess in its outside edge, and obstructs the longitudinal opening. |
| FILED | Monday, December 05, 2022 |
| APPL NO | 18/061832 |
| CURRENT CPC | Lighting Devices or Systems Thereof, Being Portable or Specially Adapted for Transportation F21L 4/027 (20130101) F21L 4/045 (20130101) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 21/145 (20130101) F21V 21/0885 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to Uses or Applications of Lighting Devices or Systems F21W 2111/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019249 | NAJAFI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Khalil NAJAFI (Ann Arbor, Michigan); Sajal SINGH (Ann Arbor, Michigan); Jae Yoong CHO (Ann Arbor, Michigan) |
| ABSTRACT | Three-dimensional (3D) micro-scale shells are presented with selectively removed regions/openings and which can be used in sensors and actuators, including gyroscopes. Example shells consisting of a suspended ring-shaped resonator that is supported using multiple beams that are not in the plane of the ring and are attached to a support post can be formed. Shells with various sizes and geometries of selectively removed regions and openings allow the creation of micro electromechanical systems (MEMS) sensors and actuators with a wide range of engineered mechanical and electrical properties. These shells can be used to form stacked 3D structures for various types of MEMS sensor and actuator devices, such as resonant gyroscopes, with sense and drive electrodes that conform to the curved profile of the resonant shell using for gyroscopes. 3D shells formed from a starting parent substrate are released and separated from their parent substrate using a number of techniques. |
| FILED | Tuesday, June 13, 2023 |
| APPL NO | 18/209454 |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 2201/0242 (20130101) B81B 2201/0271 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00444 (20130101) B81C 2201/0143 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/005 (20220101) G01C 19/5684 (20130101) G01C 19/5691 (20130101) G01C 19/5783 (20130101) Original (OR) Class Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/0072 (20130101) H03H 9/02259 (20130101) H03H 9/2405 (20130101) H03H 2009/02496 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019358 | Fan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan A. Fan (Los Altos, California); Evan W. Wang (Stanford, California); Thaibao Phan (Redwood City, California) |
| ABSTRACT | In certain examples, the present disclosure may involve use of filtering optics to provide a set of filter-separated light beams respectively associated with different polarization states of polarized light directed towards a sample, and providing a set of sample¬characterizing response data based on factors such as sets of polarization-state values, different wavelengths associated with the polarization states, and/or light-incidence angles characterizing separation of the different polarization states. More specific examples may include computing a Mueller matrix across an entire image, with the image being captured in a single shot in response to using filtering optics (e.g., metasurface polarization filtering to provide the set of filter-separated light beams). In another related example, sets of polarization-state values, corresponding Stokes vectors, may be used. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 18/034871 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/211 (20130101) Original (OR) Class G01N 2021/213 (20130101) Optical Elements, Systems, or Apparatus G02B 27/286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019458 | BARDET et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Phillipe M. BARDET (Washington, District of Columbia); Peter D. HUCK (Washington, District of Columbia); Charles FORT (Washington, District of Columbia) |
| ABSTRACT | Aspects of this disclosure are directed to optical probes for collecting images of a region of interest for determining wall shear stress. The optical probe includes an imager with a line of sight and a light guide configured to steer light from a light source to the region of interest. The optical probe includes an objective configured to focus light reflected off of the region of interest to the line of sight of the imager. The optical probe can include a micro-lens array at the objective. The micro-lens array can focus light from the objective onto the imager. The imager can collect images from the light from the micro-lens array for determining wall shear stress at the region of interest. |
| FILED | Monday, July 17, 2023 |
| APPL NO | 18/222845 |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019529 | Fleizach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory Knowles Fleizach (San Diego, California); Mark William Owen (San Diego, California); Christopher Craig Pelham (Chula Vista, California); Michael Aaron Slutsky (San Diego, California) |
| ABSTRACT | An RF pulse correlator comprising a track database, an antenna, a receiver, and a processor. The track database is configured to store established tracks of RF emissions. The antenna and receiver are configured to receive RF pulses. The tracker is configured to generate improved geolocation data for every received RF pulse based on kinematics of the received RF pulses. The processor is communicatively coupled to the database, the receiver, and the tracker. The processor is configured to associate each received RF pulse with an existing track in the track database or to create a new track. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/866601 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0257 (20130101) G01S 5/02524 (20200501) Original (OR) Class G01S 7/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019562 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhongtao Hu (St. Louis, Missouri); Hong Chen (St. Louis, Missouri) |
| ABSTRACT | A method of fabricating a binary metasurface for producing an ultrasound Airy beam for underwater ultrasound applications is provided. The method includes generating an amplitude distribution of an Airy beam at a frequency, and converting the amplitude distribution into a binary phase profile. The method also includes generating a 3D printing design of a binary metasurface based on the binary phase profile, wherein the binary metasurface includes ridges and grooves defined by neighboring ridges, a ridge having a thickness corresponding to a phase delay of π/2 of the Airy beam between water and a 3D-printable material. The method further includes additively manufacturing the binary metasurface with the 3D-printable material based on the 3D printing design. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/352700 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/00 (20141201) B33Y 70/00 (20141201) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/524 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020253 | Sharma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shruti Sharma (Beaverton, Oregon); Robert Pawlowski (Beaverton, Oregon); Fabio Checconi (Fremont, California); Jesmin Jahan Tithi (San Jose, California) |
| ABSTRACT | Systems, apparatuses and methods may provide for technology that detects a plurality of sub-instruction requests from a first memory engine in a plurality of memory engines, wherein the plurality of sub-instruction requests are associated with a direct memory access (DMA) data type conversion request from a first pipeline, wherein each sub-instruction request corresponds to a data element in the DMA data type conversion request, and wherein the first memory engine is to correspond to the first pipeline, decodes the plurality of sub-instruction requests to identify one or more arguments, loads a source array from a dynamic random access memory (DRAM) in a plurality of DRAMs, wherein the operation engine is to correspond to the DRAM, and conducts a conversion of the source array from a first data type to a second data type in accordance with the one or more arguments. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/477787 |
| CURRENT CPC | Electric Digital Data Processing G06F 13/28 (20130101) Original (OR) Class G06F 2213/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020389 | Le et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (ARMONK, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Vu Le (Danbury, Connecticut); Sanjeev Das (White Plains, New York) |
| ABSTRACT | Described are techniques for application hardening. The techniques include generating application traces using fuzzing for an application with a known security vulnerability, where the application traces include good traces that do not result in exploitation of the known security vulnerability and bad traces that result in exploitation of the known security vulnerability. The techniques further include identifying code segments that are executed by the bad traces and not executed by the good traces. The techniques further include modifying the identified code segments using binary rewriting. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/812190 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/568 (20130101) G06F 21/577 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020432 | Ginsberg |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark D Ginsberg (Champaign, Illinois) |
| ABSTRACT | Disclosed is a computer-aided design system that incorporates an airborne contaminant-flow calculator. In designing a new architectural structure, or modifying an existing one, the calculator informs the architect of the airflow ramifications of the design as the design is created or modified. The calculator uses a closed-form solution for calculating the airflow in order to present its results in a timely fashion. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/373215 |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 7/007 (20130101) F24F 11/72 (20180101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/048 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) G06F 30/13 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020563 | Akhalwaya et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ismail Yunus Akhalwaya (Emmarentia, South Africa); Shashanka Ubaru (Ossining, New York); Kenneth Lee Clarkson (Madison, New Jersey); Mark S. Squillante (Greenwich, Connecticut); Vasileios Kalantzis (White Plains, New York); Lior Horesh (North Salem, New York) |
| ABSTRACT | Systems and methods for operating quantum systems are described. A controller of a quantum system can generate a command signal. The quantum system can include quantum hardware having a plurality of qubits. An interface of the quantum system can control the quantum hardware based on the command signal to sample an input vector represented by the first set of qubits, where the input vector includes mixed states with different Hamming weights. The interface can control the quantum hardware to entangle the first set of qubits to the second set of qubits, where the second set of qubits represent a count of nonzero elements in the input vector. The interface can control the quantum hardware to generate an output vector based on the entanglement of the first set of qubits to the second set of qubits, where the output vector includes one or more states having a specific Hamming weight. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/863449 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020564 | Ubaru et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shashanka Ubaru (Ossining, New York); Kenneth Lee Clarkson (Madison, New Jersey); Ismail Yunus Akhalwaya (Emmarentia, South Africa); Mark S. Squillante (Greenwich, Connecticut); Vasileios Kalantzis (White Plains, New York); Lior Horesh (North Salem, New York) |
| ABSTRACT | Systems and methods for operating a quantum system are described. A controller of a quantum system can generate a command signal. The quantum system can include quantum hardware having a plurality of qubits. An interface of the quantum system can control the quantum hardware based on the command signal to generate a random state vector represented by the plurality of qubits. The random state vector can include a specific number of independent entries. The interface can control the quantum hardware to determine moments of a matrix based on the random state vector. The controller can be further configured to output the moments of the matrix to a computing device to estimate a trace of the matrix using the moments. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/863508 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020565 | Ubaru et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shashanka Ubaru (Ossining, New York); Ismail Yunus Akhalwaya (Emmarentia, South Africa); Kenneth Lee Clarkson (Madison, New Jersey); Mark S. Squillante (Greenwich, Connecticut); Vasileios Kalantzis (White Plains, New York); Lior Horesh (North Salem, New York) |
| ABSTRACT | Systems and methods for operating a quantum system are described. A controller of a quantum system can generate a command signal. The quantum system can include quantum hardware having a plurality of qubits. An interface of the quantum system can control the quantum hardware based on the command signal received from the controller to determine a plurality of moments of a matrix using a random state vector represented by the plurality of qubits. The controller can be further configured to output the plurality of moments of the matrix to a computing device to estimate a trace of a matrix function based on one or more selected moments among the plurality of moments. The matrix function can be a function of the matrix. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/863554 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020569 | Inoue et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ken Inoue (Elmsford, New York); MAIKA TAKITA (Croton on Hudson, New York); Antonio Corcoles-Gonzalez (Mount Kisco, New York); Scott Douglas Lekuch (New York, New York) |
| ABSTRACT | One or more systems, devices, computer program products and/or computer-implemented methods of use provided herein relate to a process to dynamically determine a threshold for determining a state of a qubit and apply the threshold for operating a pulse to de-excite the qubit. A system can comprise a memory that stores computer executable components, and a processor that executes the computer executable components stored in the memory, wherein the computer executable components can comprise a decision component that is configured to determine a threshold of a plurality of thresholds to apply to measurement of a state of a qubit based on a probability distribution of state of the qubit, wherein a measurement at one side of the threshold is representative of the qubit being in the ground state, and wherein a measurement at another side of the threshold is representative of the qubit being in an excited state. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/813082 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) G06N 10/70 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020735 | Shu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kai Shu (Tempe, Arizona); Suhang Wang (Tempe, Arizona); Jiliang Tang (Tempe, Arizona); Yilin Wang (Tempe, Arizona); Huan Liu (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Kai Shu (Tempe, Arizona); Suhang Wang (Tempe, Arizona); Jiliang Tang (Tempe, Arizona); Yilin Wang (Tempe, Arizona); Huan Liu (Tempe, Arizona) |
| ABSTRACT | Various embodiments of systems and methods for cross media joint friend and item recommendations are disclosed herein. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/114125 |
| CURRENT CPC | Electric Digital Data Processing G06F 18/2136 (20230101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 5/022 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0282 (20130101) Original (OR) Class G06Q 50/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020881 | CASE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Joseph T. CASE (Hawthorne, California); Shant KENDERIAN (Pasadena, California) |
| ABSTRACT | A method for self-determination of shot geometry for use in open-configuration portable x-ray computed tomography (CT) includes inputting one or more x-ray shot images into a computing system. The method also include determining, by the computing system, one or more shot geometries from the one or more inputted x-ray shot images. The method further includes reconstructing, by the computing system, a volume image from the one or more inputted x-ray shot images and the one or more shot geometries. The method also includes outputting, by the computing system, a reconstructed volume image. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/863490 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/80 (20170101) Original (OR) Class G06T 11/005 (20130101) G06T 2207/10081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020890 | CASE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Joseph T. CASE (Hawthorne, California); Shant KENDERIAN (Pasadena, California) |
| ABSTRACT | Self-determined shot geometry for open-configuration portable x-ray computed tomography (CT) includes capturing one or more x-ray shot images into a computing system, and estimating an unknown constellation model and one or more shot geometries. It also includes reconstructing a volume image from the one or more captured shot images and the one or more geometries using computed tomography. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 18/051052 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 11/005 (20130101) G06T 11/008 (20130101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2207/10116 (20130101) G06T 2211/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240021336 | NEMANICK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Eric Joseph NEMANICK (Santa Monica, California); Henry HELVAJIAN (Pasadena, California); Adon DELGADO, JR. (West Hills, California); Kristine L. FERRONE (Pasadena, Texas) |
| ABSTRACT | Scalable radioisotope power tiles that can provide heat, electrical power, or both, are disclosed. Unlike conventional radioisotope thermoelectric generator (RTG) designs, the scalable radioisotope power tiles do not necessarily seek to minimize the RTG surface area. Rather, a planar design may be used to maximize the radiative surface to increase the temperature difference (ΔT) and increase system heat to electricity conversion efficiency where electrical power generation is desired. In addition, such a planar design can be one-sided or two-sided, allowing for flexibility in design. For instance, such power tiles may be deployed in a material like a solar sail, on the surface of a vehicle, in terrestrial systems, etc. |
| FILED | Thursday, July 14, 2022 |
| APPL NO | 17/864864 |
| CURRENT CPC | Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 1/103 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240021804 | Gerasopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Konstantinos Gerasopoulos (Highland, Maryland); Matthew W. Logan (Columbia, Maryland); Bing Tan (Ann Arbor, Michigan) |
| ABSTRACT | Aspects of the disclosure describe an energy storage device comprising a cathode, an anode, a separator, and an electrolyte. The anode comprises a support structure and an electrode layer disposed on the support structure. The electrode layer comprises 40-80% silicon, 15-40% graphite, 5-15% carbon black, 0-15% carboxymethyl cellulose (CMC), 0-5% styrene-butadiene rubber (SBR), and 5-20% poly(acrylic acid). The separator is disposed between the anode and cathode to prevent internal shorting of the energy storage device. The electrolyte allows movement of ions between the anode and cathode. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/865867 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/386 (20130101) Original (OR) Class H01M 4/587 (20130101) H01M 4/622 (20130101) H01M 10/0565 (20130101) H01M 2004/021 (20130101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240021873 | WIDSTROM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | High Performance Air Stable Solid Polymer Electrolyte (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Matthew D. WIDSTROM (Ellicott City, Maryland); Peter KOFINAS (N. Bethesda, Maryland); Arthur V. CRESCE (Beltsville, Maryland); Kang XU (Potomac, Maryland) |
| ABSTRACT | The present invention is directed to aqueous solid polymer electrolytes that comprise a lithium salt and battery cells comprising the same. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies. |
| FILED | Thursday, April 06, 2023 |
| APPL NO | 18/131745 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/505 (20130101) H01M 4/5825 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240022247 | Ubaru et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shashanka Ubaru (Ossining, New York); Ismail Yunus Akhalwaya (Emmarentia, South Africa); Mark S. Squillante (Greenwich, Connecticut); Kenneth Lee Clarkson (Madison, New Jersey); Vasileios Kalantzis (White Plains, New York); Lior Horesh (North Salem, New York) |
| ABSTRACT | Systems and methods for performing pairwise checking of data points in a dataset are described. An apparatus or computing device can include a controller, quantum hardware, and an interface. The controller can be configured to generate a command signal. The quantum hardware can include a plurality of qubits. The interface can be connected to the controller and the quantum hardware. The interface can be configured to control the quantum hardware based on the command signal received from the controller to perform pairwise checking for every pair of data points in a dataset to identify a property relating to the data points. The data points can be represented by the plurality of qubits. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/863484 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) G06N 10/60 (20220101) Pulse Technique H03K 17/92 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240017209 | THOMAS-ALYEA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VERDOX, INC. (Wobum, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karen THOMAS-ALYEA (Arlington, Massachusetts); Sahag VOSKIAN (Boston, Massachusetts); Cameron ROGERS (Malden, Massachusetts); Alexander REATH (Melrose, Massachusetts) |
| ABSTRACT | A composite includes a nonwoven carbon nanotube mat and an electroactive species disposed on the nonwoven carbon nanotube mat, wherein the electroactive species is capable of bonding with a target gas when the electroactive species is in a reduced state and releasing the target gas when the electroactive species is in an oxidized state. Electrode assemblies, electro-chemical cells, and gas separation systems including the composite are also described herein. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 18/035968 |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/326 (20130101) Original (OR) Class B01D 53/965 (20130101) B01D 2253/25 (20130101) B01D 2253/102 (20130101) B01D 2253/304 (20130101) B01D 2253/311 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/168 (20170801) C01B 2202/34 (20130101) C01B 2202/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017212 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TerraPower, LLC (Bellevue, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sally A. Miller (Seattle, Washington); Christopher M. Regan (Seattle, Washington); Jonathan E. Truax (Bellevue, Washington) |
| ABSTRACT | A method of removing cesium vapor from a cover gas stream in a nuclear reactor includes the steps of oxidizing the cesium vapor in the cover gas stream to yield cesium oxide particles and removing the cesium oxide particles using a particle filter. The method yields a filtered cover gas having zero to about 2% of the cesium vapor content of the initial cover gas stream, representing a reduction of at least about 98 percent. |
| FILED | Tuesday, April 18, 2023 |
| APPL NO | 18/302778 |
| CURRENT CPC | Separation B01D 39/2027 (20130101) B01D 53/46 (20130101) B01D 53/82 (20130101) Original (OR) Class B01D 2251/102 (20130101) B01D 2251/602 (20130101) B01D 2257/93 (20130101) Nuclear Reactors G21C 19/303 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017215 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SiTration, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | SiTration, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Brendan D. Smith (Cambridge, Massachusetts); Jatin Patil (Cambridge, Massachusetts); Daniel Bregante (Cambridge, Massachusetts); Ahmed Helal (Cambridge, Massachusetts); Hee Yun Choi Kim (Cambridge, Massachusetts); Morgan Baima (Cambridge, Massachusetts); Jeffrey C. Grossman (Cambridge, Massachusetts); Noah Letwat (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure relates to systems and methods for electrically conductive membrane separation from a mixture solution via membrane nanofiltration, electro-filtration, or electro-extraction by: generating an electric field at the membrane filter, holding the membrane filter at a constant electric potential, or driving a constant current through the membrane filter; feeding a mixture solution through the membrane nanofiltration system; and separating a component from the mixture solution into a permeate solution. |
| FILED | Monday, October 02, 2023 |
| APPL NO | 18/212590 |
| CURRENT CPC | Separation B01D 61/08 (20130101) Original (OR) Class B01D 61/027 (20130101) B01D 67/0062 (20130101) B01D 67/0072 (20130101) B01D 69/02 (20130101) B01D 71/0213 (20220801) B01D 2313/365 (20130101) B01D 2323/28 (20130101) B01D 2325/26 (20130101) B01D 2325/02833 (20220801) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/24 (20130101) C23C 16/50 (20130101) C23C 16/56 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/30 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017348 | Pagan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| INVENTOR(S) | Michael Barnes Pagan (Knoxville, Tennessee) |
| ABSTRACT | Provided are methods and apparatus for bonding metals. In an example, a provided method includes (i) disposing a layer of Vanadium onto a first Titanium surface of a first tangible object, (ii) placing a second Titanium surface of a second tangible object in direct contact with the layer of Vanadium, and (iii) imparting, using a sonotrode, compressive and shear forces to the first Titanium surface, the layer of Vanadium, and the second Titanium surface, to cause plastic deformation that bonds the first Titanium surface to the second Titanium surface. |
| FILED | Wednesday, May 31, 2023 |
| APPL NO | 18/326310 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/103 (20130101) Original (OR) Class B23K 2103/14 (20180801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017448 | LOJEK, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | John LOJEK, III (Latrobe, Pennsylvania); Matthew M. SWARTZ (Claridge, Pennsylvania); William A. BYERS (Murrysville, Pennsylvania) |
| ABSTRACT | A forming assembly configured to form a wick is disclosed. The forming assembly includes an expandable tube and a forming shell assembly. The expandable tube is hydraulically expandable to an expanded configuration. A wick mesh is configured to be wrapped about the expandable tube. The forming shell assembly includes a first forming shell comprising a first recess defined therein and a second forming shell comprising a second recess defined therein. The first recess and the second recess cooperate to define an outer diameter of the wick. The expandable tube and the wick mesh are positionable between the first recess and the second recess. The expandable tube and the forming shell assembly are configured to deform the wick mesh and form the wick based on the expandable tube hydraulically expanding towards the expanded configuration. |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/362689 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/10 (20130101) Original (OR) Class B29C 43/3642 (20130101) B29C 2043/3602 (20130101) B29C 2043/3649 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017484 | Saito et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tomonori Saito (Oak Ridge, Tennessee); Amelia M. Elliott (Oak Ridge, Tennessee); Dustin B. Gilmer (Oak Ridge, Tennessee); Lu Han (Oak Ridge, Tennessee) |
| ABSTRACT | A method of binder jet additive manufacturing (BJAM) is provided. The method includes feeding a supply of powder particles to a powder bed, delivering an organic binder onto the powder bed in select locations of each layer to form a porous green part, and introducing to the binder a secondary component that chemically reacts with the binder to form a solid polymer matrix around the powder particles. The secondary component is introduced either by: (i) infiltration of the secondary component into the porous green part; or (ii) by combining the secondary component with the powder particles prior to feeding the powder particles to the powder bed. A binder system for BJAM is also provided. The binder system includes a reactive pair including an organic binder that is capable of being deposited on a powder bed; and a secondary component that is reactive with the organic binder. |
| FILED | Monday, July 17, 2023 |
| APPL NO | 18/222645 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/14 (20210101) B22F 2999/00 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018006 | Bhattacharya et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sumit Bhattacharya (Darien, Illinois); Daniel Abraham (Bolingbrook, Illinois); Abdellatif M. Yacout (Naperville, Illinois) |
| ABSTRACT | A method of the producing nanocrystalline silicon particulate from a silicate source includes removing contaminants, such as organics and heavy metals, and alumina from the silicate source by treating the silicate source with first and second acidic leaching solutions to form a first intermediate product. The first intermediate product is then reduced by reacting with a magnesium vapor to provide porous magnesiated silicon particulates as a second intermediate product. The second intermediate product is treated with a third leaching solution to remove magnesium and magnesium containing compounds form the second intermediate to thereby provide a third intermediate. The third intermediate is treated with a fourth leaching solution for removing remnant silica to thereby provide nanocrystalline porous silicon particles. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/812419 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/039 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018194 | GRUVER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PIONEER HI-BRED INTERNATIONAL, INC. (JOHNSTON, Iowa) |
| ASSIGNEE(S) | PIONEER HI-BRED INTERNATIONAL, INC. (JOHNSTON, Iowa) |
| INVENTOR(S) | STEVEN D. GRUVER (PACIFICA, California); HEATHER KOZY (WALNUT CREEK, California); JESSICA O'REAR (REDWOOD CITY, California); BARBARA ROSEN (MOUNTAIN VIEW, California); UTE SCHELLENBERGER (PALO ALTO, California); JUN-ZHI WEI (JOHNSTON, Iowa); WEIPING XIE (EAST PALO ALTO, California); XIAOHONG ZHONG (SAN LEANDRO, California); GENHAI ZHU (SAN JOSE, California) |
| ABSTRACT | Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity. |
| FILED | Wednesday, August 30, 2023 |
| APPL NO | 18/458232 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) A01N 63/50 (20200101) Peptides C07K 14/21 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8286 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018416 | Schmidt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Andrew J. Schmidt (Richland, Washington); Lesley J. Snowden-Swan (Ellensburg, Washington); David B. Spry (Prairieville, Louisiana) |
| ABSTRACT | A hydrothermal liquefaction (HTL) system has a biomass slurry flow path with a first pump and a first heat exchanger network downstream of the first pump. The first heat exchanger network includes plurality of heat exchangers in a parallel, series, and/or series-parallel flow arrangement. The biomass slurry flow path extends through cold flow sides of the heat exchangers of the first heat exchanger network. The biomass slurry flow path includes a second pump downstream of the first heat exchanger network, and a second heat exchanger network downstream of the second pump. The biomass slurry flow path extends through cold flow sides of the heat exchangers of the second heat exchanger network. A hydrothermal liquefaction (HTL) reactor is downstream of the second heat exchanger network. Heat transfer liquid in a heat transfer liquid circuit flows through hot flow sides of the heat exchangers of the second heat exchanger network. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/352551 |
| CURRENT CPC | Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 47/20 (20130101) Original (OR) Class C10B 53/00 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/047 (20130101) C10G 2300/1003 (20130101) C10G 2300/1011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018527 | Liew et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LanzaTech, Inc. (Skokie, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fungmin Liew (Chicago, Illinois); Michael Koepke (Chicago, Illinois) |
| ABSTRACT | Microorganisms are genetically engineered to produce 3-hydroxypropionate (3-HP). The microorganisms are carboxydotrophic acetogens. The microorganisms produce acetyl-coA using the Wood-Ljungdahl pathway for fixing CO/CO2. A β-alanine pyruvate aminotransferase from a microorganism that contains such an enzyme is introduced. Additionally, an acetyl-coA carboxylase may also be introduced. The production of 3-HP can be improved. This can be effected by improved promoters or higher copy number or enzymes that are catalytically more efficient. |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/457299 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/93 (20130101) C12N 9/1096 (20130101) C12N 15/52 (20130101) Original (OR) Class C12N 15/74 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/18 (20130101) C12P 7/42 (20130101) Enzymes C12Y 101/01001 (20130101) C12Y 102/01075 (20130101) C12Y 102/07005 (20130101) C12Y 206/01018 (20130101) C12Y 604/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018555 | BECKHAM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregg Tyler BECKHAM (Golden, Colorado); Lucas Delano ELLIS (Corvallis, Oregon); Kevin P. SULLIVAN (Golden, Colorado); Allison Jean Zimont WERNER (Denver, Colorado) |
| ABSTRACT | The provided methods and systems describe the breakdown of plastic materials into valuable products, thereby both eliminating waste and providing reusable materials. The described systems and methods utilize catalytic depolymerization and biological funneling via bacteria, which may reduce the costs of recycling plastics in terms of expensive catalysts, energy, and time. Advantageously, some embodiments may target mixed plastic streams, which due to having multiple chemical compositions, may not be easily recycled via conventional recycling techniques. Such mixed plastic streams are currently often discarded (e.g., landfilled) rather than recycled due to the cost and effort required for separating the various compositions present. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/256542 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/16 (20130101) C08J 11/28 (20130101) C08J 11/105 (20130101) C08J 2327/08 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/50 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018556 | LINGER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey George LINGER (Denver, Colorado); Christine Ann SINGER (Lakewood, Colorado); Lauren Ann Riley DRUMM (Superior, Colorado); Michael T. GUARNIERI (Denver, Colorado); Davinia SALVACHÚA RODRÍGUEZ (Golden, Colorado); Colin Matthew KNEUCKER (Fort Collins, Colorado); Violeta SANCHEZ NOGUE (Broomfield, Colorado) |
| ABSTRACT | Clostridium sp. are an obligate anaerobic bacterium that produces butyric acid as its major end-product. Previously, we have developed an integrated process that couples fermentation of biomass sugars, with in situ product recovery and distillation. This process works best at pH's lower than 7.0. The process serves to extract carboxylic acids during fermentation which enables reduced base-loading and reduced end-product toxicity. Disclosed herein are methods and non-naturally Clostridium sp. that are capable of increased production of butyric acid and increased growth at low pH conditions (e.g., pH<5.0). |
| FILED | Monday, July 17, 2023 |
| APPL NO | 18/353673 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0014 (20130101) C12N 9/88 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/52 (20130101) Original (OR) Class Enzymes C12Y 104/99 (20130101) C12Y 401/01018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018560 | McBrayer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novozymes, Inc. (Davis, California) |
| ASSIGNEE(S) | Novozymes, Inc. (Davis, California) |
| INVENTOR(S) | Brett McBrayer (Sacramento, California); Elena Vasenko (Davis, California); Tarana Shaghasi (Guerneville, California) |
| ABSTRACT | The present invention relates to enzyme compositions for high temperature saccharification of cellulosic material and to uses thereof. |
| FILED | Tuesday, June 13, 2023 |
| APPL NO | 18/333776 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/22 (20130101) C12N 9/248 (20130101) C12N 9/2402 (20130101) C12N 9/2437 (20130101) C12N 9/2445 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/12 (20130101) C12P 19/14 (20130101) Original (OR) Class C12P 21/02 (20130101) C12P 2203/00 (20130101) Enzymes C12Y 302/01 (20130101) C12Y 302/01004 (20130101) C12Y 302/01008 (20130101) C12Y 302/01021 (20130101) C12Y 302/01037 (20130101) C12Y 302/01091 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019393 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wenzhuo Wu (West Lafayette, Indiana); Jing Jiang (West Lafayette, Indiana) |
| ABSTRACT | An electrochemical sensor that includes a substrate and a piezoelectric semiconductor which is configured to detect uric acid using piezo-electrocatalysis. The piezoelectric semiconductor is coupled to the substrate. The piezoelectric semiconductor includes a nanostructured semiconducting ZnO catalyst. The nanostructured semiconducting ZnO catalyst has a noncentrosymmetric wurtzite configuration. The nanostructured semiconducting ZnO catalyst is shaped as a nanorod and/or a nanosheet. |
| FILED | Wednesday, September 27, 2023 |
| APPL NO | 18/373412 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019593 | CHRISTY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | JEFFERSON SCIENCE ASSOCIATES, LLC (Newport News, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | M. ERIC CHRISTY (SEAFORD, Virginia); CYNTHIA KEPPEL (Newport News, Virginia) |
| ABSTRACT | A Proton Computed Tomography (pCT) system utilizing proton beams for construction of 3-dimensional density maps of both test phantoms and living tissue. PCT is a much sought-after modality for treatment planning and validation at proton therapy treatment centers, as it would allow in situ imaging with the same beam that is used for the treatment. A pCT system according to the present invention includes gaseous detectors for tracking and energy reconstruction, a shutter system to extend dynamic range features while maintaining good energy resolution, and a method for determining proton energy from a forward-search algorithm utilizing segmentation of energy detector ionization signal readout. The gaseous detectors are Gas Electron Multiplier (GEM) based gaseous detectors. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/222131 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Measurement of Nuclear or X-radiation G01T 1/205 (20130101) Original (OR) Class G01T 1/1641 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020434 | Urick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | nVariate, Inc. (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin Urick (Roseville, California); Richard H. Crawford (Austin, Texas); Daniel L. Keller (Waitsfield, Vermont); Lisa A. Torres (Austin, Texas) |
| ABSTRACT | Methods and computer systems for methods, computer systems, and computer-readable memory media for determining a warp function. A first watertight spline model of a first object and a set of points and associated metadata from a second object are received. A second watertight spline model of the second object is constructed based on the set of points, the metadata, and the first watertight spline model. A warp function is determined based on a difference between the first watertight spline model and the second watertight spline model. The warp function is a continuous function approximating differences between the first object and the second object. The warp function is stored in a non-transitory computer-readable memory medium. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/352871 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/17 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020833 | Ovchinnikova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Olga S. Ovchinnikova (Knoxville, Tennessee); Jacob D. Hinkle (Oak Ridge, Tennessee); Inzamam Haque (Knoxville, Tennessee); Debangshu Mukherjee (Knoxville, Tennessee) |
| ABSTRACT | Systems, methods and programs including machine learning techniques which can predict a spectral image directly from an optical image of a patient's tissue sample using a first model. There may be different first models for different cancers. Each first model may be trained by using a plurality of pairs of images from different samples, respectively, where each image in a respective pair may be obtained via different imaging modalities. The systems, methods and programs may also include machine learning techniques which can predict cancer labels from the predicted spectral image using a second model. There may be different second models for different cancers. Each second model may be trained using multiple spectral images and corresponding manually input cancer labels. |
| FILED | Friday, June 23, 2023 |
| APPL NO | 18/340306 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 7/0012 (20130101) Original (OR) Class G06T 2200/24 (20130101) G06T 2207/10056 (20130101) G06T 2207/20016 (20130101) G06T 2207/20081 (20130101) G06T 2207/30081 (20130101) G06T 2207/30088 (20130101) G06T 2207/30096 (20130101) G06T 2207/30204 (20130101) Image or Video Recognition or Understanding G06V 10/774 (20220101) G06V 10/7715 (20220101) G06V 20/698 (20220101) G06V 2201/03 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240021777 | HU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lianbing HU (Rockville, Maryland); Eric D. WACHSMAN (Fulton, None); Boyang LIU (Columbia, Maryland); Liu ZHANG (Berwyn Heights, Maryland); Shaomao XU (College Park, Maryland); Dennis MCOWEN (Washington, District of Columbia); Chunpeng YANG (Berwyn Heights, Maryland); Hua XIE (College Park, Maryland) |
| ABSTRACT | The present disclosure provides an anode assembly for a lithium ion battery. The anode assembly comprises an anode, a ceramic separator, and an amorphous carbon coating. The anode comprises a first porous ceramic matrix having pores. The ceramic separator layer is coupled to the anode. The amorphous carbon coating is disposed at least partially on a surface of the first porous ceramic matrix. The present disclosure also provides a lithium-ion battery. The present disclosure further provides a method of forming an anode assembly for a lithium-ion battery. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/220700 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/0426 (20130101) Original (OR) Class H01M 4/587 (20130101) H01M 4/1393 (20130101) H01M 10/0525 (20130101) H01M 50/46 (20210101) H01M 50/434 (20210101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240021796 | BROW et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan Ray BROW (Denver, Colorado); Shriram SANTHANAGOPALAN (Broomfield, Colorado); Alexis Rose LUGLIO (Wayne, New Jersey) |
| ABSTRACT | The present disclosure relates to mitigation strategies to limit particle fracture and surface degradation caused by air instability. Some embodiments include cobalt-free nickel-rich NMA (LiNi0.9Mn0.5Al0.05O2) being ball-milled to effectively “pre-crack” the secondary particles into their primary constituents or single crystallites. These NMA particles may be coated with lithium phosphate and/or phosphoric acid. After approximately 100 cycles, these pulverized NMA particles showed delay voltage decay and approximately double the discharge capacity compared to traditional pristine NMA cathode materials during high-voltage cycling. |
| FILED | Thursday, October 27, 2022 |
| APPL NO | 18/050124 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/50 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/5825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240022110 | Debnath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Suman Debnath (Oak Ridge, Tennessee); Phani Ratna Vanamali Marthi (Oak Ridge, Tennessee); Rafal P. Wojda (Oak Ridge, Tennessee); Qianxue Xia (Oak Ridge, Tennessee); Maryam Saeedifard (Oak Ridge, Tennessee) |
| ABSTRACT | An autonomous reconfigurable system has arms terminating at inductors. The inductors are connected to a photovoltaic submodule, an energy storage system submodule, and a submodule that source a direct current voltage and an alternating current voltage. A central processor controller determines arm modulation indices and issues reference power commands for the submodules and detects cyber-attacks and/or bad data threats. A field programmable gate array disaggregates monitored variables monitored from each arm. Multiple digital signal processor controllers communicate with each of the each of the submodules. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/219860 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/554 (20130101) G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/381 (20130101) H02J 13/00002 (20200101) Original (OR) Class H02J 2203/10 (20200101) H02J 2203/20 (20200101) H02J 2300/22 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240022174 | AMIRABADI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mahshid AMIRABADI (Sudbury, Massachusetts); Mojtaba SALEHI (Boston, Massachusetts); Masih KHODABANDEH (Escondido, California) |
| ABSTRACT | A power conversion device includes an input stage from an unregulated power source to a switching circuit that is coupled to a thin film link capacitor. In some embodiments, the link stage permits soft switching. Further, a high frequency transformer may be utilized for management of voltage acquired from the circuit. Thus, a managed voltage may be supplied to an electrical load via a capacitor of reduced size and weight and with improved efficiency and reliability. |
| FILED | Tuesday, July 18, 2023 |
| APPL NO | 18/223513 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/0058 (20210501) H02M 3/335 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240023443 | Pandelidis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | B aryon Inc. (Wilmington, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Demis Lukasz Pandelidis (Wroclaw, Poland); Korneliusz Sierpowski (Wroclaw, Poland); Jeffrey Premer (Las Vegas, Nevada) |
| ABSTRACT | The present disclosure relates to an evaporative heat exchanger enhanced with thermoelectric generators which allow for the collection of electrical energy during heat transfer process. The present disclosure consists of a heat exchanger. |
| FILED | Thursday, May 18, 2023 |
| APPL NO | 18/198960 |
| CURRENT CPC | Electric solid-state devices not otherwise provided for H10N 10/17 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20240016398 | Ramella-Roman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jessica Claudia Ramella-Roman (Miami, Florida); Tananant Boonya-Ananta (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Jessica Claudia Ramella-Roman (Miami, Florida); Tananant Boonya-Ananta (Miami, Florida) |
| ABSTRACT | Systems, devices, and methods for measuring blood pressure without the use of a pump are provided. A pumpless blood pressure measuring system or device can be wearable for long periods of time comfortably. The pumpless blood pressure measuring system or device can include a body, at least one tension band connected to the body, at least one pressure sensor configured to be in direct physical contact with the user's body, and a tourniquet mechanism. The tourniquet mechanism can be tightened to lead to artery occlusion such that the at least one pressure plate can determine the blood pressure of the user/wearer. |
| FILED | Friday, June 09, 2023 |
| APPL NO | 18/332252 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/681 (20130101) A61B 5/742 (20130101) A61B 5/02233 (20130101) Original (OR) Class A61B 2562/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016561 | Majewicz Fey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ann Majewicz Fey (Austin, Texas); Jacob R. Boehm (Bedford, Texas); Nicholas P. Fey (Jonestown, Texas) |
| ABSTRACT | Systems, methods and computer program products for online recognition of bimanual or bipedal coordination modes directed to completing a task using a robot. Such a method includes the steps of determining an onset of bimanual or bipedal motion of a subject operating the robot, and, in response, receiving trajectory data of left and right hands, or left and right feet, of the subject. The method also includes the step(s) of computing, based on the trajectory data, geometric descriptors of the segment, which include a direction metric and a symmetry metric. The method further includes the step(s) classifying, based on the direction and symmetry metrics, the types of direction and symmetry for the segment. The method also includes at least one of the steps of: generating task performance feedback, and controlling the robot, based on the types of direction and symmetry. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/348329 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00 (20130101) A61B 34/25 (20160201) A61B 34/37 (20160201) Original (OR) Class A61B 2017/00207 (20130101) A61B 2034/252 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017258 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abraham P. Lee (Irvine, California); Xuhao Luo (Irvine, California); Braulio Cárdenas Benítez (Irvine, California) |
| ABSTRACT | A microfluidic platform comprising an inlet, a fluidic chamber, one or more trapping arrays, each trapping array comprising pillars separated by gaps, an outlet, and a droplet generator fluidly coupled to the inlet. The droplet generator may accept one or more particles and output particle-laden droplets comprising a particle surrounded by an aqueous solution surrounded by a carrier oil. The particle-laden droplets directed from the droplet generator, through the inlet, to the fluidic chamber, may be immobilized by the one or more trapping arrays. The droplet generator may generate a continuous flow of carrier oil through the inlet and through the fluidic chamber. The continuous flow of carrier oil may induce one or more microvortices at the one or more trapping arrays. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/353005 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) Original (OR) Class B01L 2300/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017311 | Quigley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (North Potomac, Maryland) |
| ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods. |
| FILED | Monday, April 10, 2023 |
| APPL NO | 18/132753 |
| CURRENT CPC | Reclamation of Contaminated Soil B09C 1/005 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/00 (20130101) E21B 43/12 (20130101) E21B 47/06 (20130101) E21B 49/0875 (20200501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017401 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wenlong Zhang (Chandler, Arizona); Pham Huy Nguyen (Mesa, Arizona); Zhi Qiao (Tempe, Arizona); Sam Seidel (Scottsdale, Arizona); Imran I.B. Mohd (Tempe, Arizona); Sunny Amatya (Mesa, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wenlong Zhang (Chandler, Arizona); Pham Huy Nguyen (Mesa, Arizona); Zhi Qiao (Tempe, Arizona); Sam Seidel (Scottsdale, Arizona); Imran I.B. Mohd (Tempe, Arizona); Sunny Amatya (Mesa, Arizona) |
| ABSTRACT | A soft continuum robotic module comprises a plurality of inflatable actuators disposed between plates. Via inflation or deflation of one or more of the actuators, the module may extend, contract, twist, bend, and/or exert a grasping force. One or more modules may be combined to form a robotic arm with multiple degrees of freedom. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/174273 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/142 (20130101) Original (OR) Class B25J 9/1075 (20130101) B25J 13/088 (20130101) B25J 18/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017426 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yu Sun (Tampa, Florida); Adheesh Shenoy (Tampa, Florida); Tianze Chen (Tampa, Florida); Francis Tsow (Tampa, Florida) |
| ABSTRACT | Systems and methods for multiple object transferring using robotics. A system includes a robotic hand with a base and fingers capable of grasping objects. A robotic arm is coupled to the robotic hand and is capable of moving the robotic hand. One or more circuits are configured to operate the robotic hand and the robotic arm by identifying a pre-grasp configuration for the robotic hand and executing a transfer routine based on a Markov decision process model to operate the robotic hand and the robotic arm such that they move multiple objects from a first location to a second location. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/352843 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1664 (20130101) B25J 15/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018055 | Corral |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erica Corral (Tucson, Arizona) |
| ABSTRACT | Disclosed are ceramic powder compositions that include Si, N, O, C, Mg, and/or Mn in tailored combinations of different crystalline phases for producing high temperature resistant and high strength ceramic products. In some aspects, a ceramic powder for producing high temperature-resistant and/or high mechanical strength materials comprises a silicon nitride (Si3N4) powder, comprising Si3N4 particles having a size within a range of 30 nm to 700 nm, wherein the Si3N4 powder include alpha and beta phase silicon nitride in an amount up to about 1-100% vol; and an impurity constituent intermixed with the Si3N4 powder within the ceramic powder, the impurity constituent comprising at least one of silicon (Si), nitrogen (N), oxygen (O), carbon (C), magnesium (Mg), or manganese (Mn), wherein the impurity constituent constitutes less than about 0.1% wt to 15% wt of the ceramic powder. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 18/258449 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/593 (20130101) Original (OR) Class C04B 2235/77 (20130101) C04B 2235/87 (20130101) C04B 2235/785 (20130101) C04B 2235/3882 (20130101) C04B 2235/5454 (20130101) C04B 2235/6567 (20130101) C04B 2235/9607 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018528 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ross D. Jones (Vancouver, Canada); Yili Qian (Madison, Wisconsin); Domitilla Del Vecchio (Cambridge, Massachusetts); Ron Weiss (Newton, Massachusetts) |
| ABSTRACT | Provided herein are feedback controller circuits and cell state classifiers for tunable phosphorylation-based transcriptional regulation of gene expression in cells based on intracellular miRNA profiles and degradation by small molecules. Also provided are methods of using feedback controller circuits and cell state classifiers for determining the cell state, and methods of treating cells and subjects using feedback controller circuits and cell state classifiers encoding therapeutic output molecules. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 18/039583 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 48/0066 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) C12N 15/635 (20130101) Original (OR) Class C12N 2830/001 (20130101) Enzymes C12Y 207/13003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018573 | KARTALOV et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emil P. KARTALOV (PASADENA, California); Aditya RAJAGOPAL (ORANGE, California); Axel SCHERER (BARNARD, Vermont) |
| ABSTRACT | This disclosure provides methods, systems, compositions, and kits for the multiplexed detection of a plurality of analytes in a sample. In some examples, this disclosure provides methods, systems, compositions, and kits wherein multiple analytes may be detected in a single sample volume by acquiring a cumulative measurement or measurements of at least one quantifiable component of a signal. In some cases, additional components of a signal, or additional signals (or components thereof) are also quantified. Each signal or component of a signal may be used to construct a coding scheme which can then be used to determine the presence or absence of any analyte. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/352112 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6851 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 25/00 (20190201) G16B 25/20 (20190201) G16B 40/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018643 | Rajagopalan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jagannathan Rajagopalan (Tempe, Arizona); Rohit Berlia (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jagannathan Rajagopalan (Tempe, Arizona); Rohit Berlia (Tempe, Arizona) |
| ABSTRACT | Synthesis of high SFE nanotwinned metallic films with varying distributions of twin widths on a low SFE metallic layer using magnetron sputtering is disclosed. In various embodiments, a method for forming a nanotwinned metal film may include providing a single crystal silicon wafer, etching the single crystal silicon wafer, depositing a silver film onto the single crystal silicon wafer forming a silver buffer layer, and depositing a metallic film onto the silver buffer layer using sputtering at a controlled temperature. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/350138 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/18 (20130101) Original (OR) Class C23C 14/021 (20130101) C23C 14/025 (20130101) C23C 14/35 (20130101) C23C 14/542 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018667 | Dansereau |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Spencer Dansereau (Boulder, Colorado) |
| ABSTRACT | Provided herein is a method and apparatus for directly converting gaseous CO2 into useful materials such as carbon fiber. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/352772 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/158 (20170801) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/135 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019353 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiao Wang (Cambridge, Massachusetts); Jia Liu (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed herein are methods and systems for correlating continuous physiological processes (e.g., electrophysiological activity) and biomolecular processes (e.g., gene expression) in cells within a tissue. Also disclosed herein are methods for preparing a tissue for continuous electrophysiological recording. Further disclosed herein are systems comprising nanoelectronic devices within cells in a tissue, wherein each nanoelectronic device comprises a unique electronic barcode. The methods and systems described herein comprise any tissue with electrical activity (e.g., brain tissue, heart tissue, nervous system tissue, muscle tissue, pancreas tissue, or gastrointestinal tract tissue). Additionally disclosed herein are methods for disease modeling, methods for discovering a target for treating a disease, and methods for drug screening. |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 18/033754 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1031 (20130101) Original (OR) Class G01N 27/3278 (20130101) G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019360 | Pastrana-Rios |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PROTEIN DYNAMIC SOLUTIONS, INC. (Wakefield, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Belinda Pastrana-Rios (Wakefield, Massachusetts) |
| ABSTRACT | The disclosure relates to methods and systems for the analysis of compounds in a crystalline state and/or undergoing crystallization. Two-dimensional correlation (2DCOS) and co-distribution analysis (2 DCDS) analysis plots can be generated and analyzed. Asynchronous plots can aid in establishing a sequential order of events. Positive cross peaks that correlate with auto peaks associated with aggregation can be identified. The auto peaks can be referenced to quickly discern the regions of the molecule most perturbed, which would indicate a driver for the crystallization state of the molecule. One can define which functional group types (e.g., region) are most perturbed (positive, intense auto peak) and observe how the different auto peaks begin to have greatest intensity change. These changes in auto peaks in the synchronous plots for the different stages of crystallization can provide information as to the dynamics of the process from amorphous to crystalline state. |
| FILED | Tuesday, August 22, 2023 |
| APPL NO | 18/453533 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) Original (OR) Class G01N 33/6806 (20130101) G01N 2021/3595 (20130101) G01N 2201/1248 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019398 | Litvinov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Dmitri Litvinov (Friendswood, Texas); Long Chang (Pearland, Texas); Richard Willson (Houston, Texas) |
| ABSTRACT | A biosensor may provide a magnetoresistive (MR) film comprising a nonmagnetic layer may be sandwiched between the two ferromagnetic layers. The MR film may be positioned on a substrate, where the edges of the MR film are in contact with leads. The leads may be in contact with pads. The sensors may provide quasi-digital readout that enable greatly enhanced sensitivity. In some embodiments, biosensors may be arranged as array of sensors. The array of sensors may be arranged as a symmetric or asymmetric N1×N2 array, where N1 and N2 are integers, N1 represents the number of sensors linked together in series, and N2 represents the number of sensor sets in parallel, where each sensor set may comprise one or more sensors. Further, the array of sensors may be coupled to a voltmeter, which may be a single voltmeter in that allows the sensors to all be probed simultaneously. |
| FILED | Monday, September 25, 2023 |
| APPL NO | 18/372558 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/745 (20130101) Original (OR) Class G01N 33/54326 (20130101) G01N 33/54346 (20130101) G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020253 | Sharma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shruti Sharma (Beaverton, Oregon); Robert Pawlowski (Beaverton, Oregon); Fabio Checconi (Fremont, California); Jesmin Jahan Tithi (San Jose, California) |
| ABSTRACT | Systems, apparatuses and methods may provide for technology that detects a plurality of sub-instruction requests from a first memory engine in a plurality of memory engines, wherein the plurality of sub-instruction requests are associated with a direct memory access (DMA) data type conversion request from a first pipeline, wherein each sub-instruction request corresponds to a data element in the DMA data type conversion request, and wherein the first memory engine is to correspond to the first pipeline, decodes the plurality of sub-instruction requests to identify one or more arguments, loads a source array from a dynamic random access memory (DRAM) in a plurality of DRAMs, wherein the operation engine is to correspond to the DRAM, and conducts a conversion of the source array from a first data type to a second data type in accordance with the one or more arguments. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/477787 |
| CURRENT CPC | Electric Digital Data Processing G06F 13/28 (20130101) Original (OR) Class G06F 2213/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240022174 | AMIRABADI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mahshid AMIRABADI (Sudbury, Massachusetts); Mojtaba SALEHI (Boston, Massachusetts); Masih KHODABANDEH (Escondido, California) |
| ABSTRACT | A power conversion device includes an input stage from an unregulated power source to a switching circuit that is coupled to a thin film link capacitor. In some embodiments, the link stage permits soft switching. Further, a high frequency transformer may be utilized for management of voltage acquired from the circuit. Thus, a managed voltage may be supplied to an electrical load via a capacitor of reduced size and weight and with improved efficiency and reliability. |
| FILED | Tuesday, July 18, 2023 |
| APPL NO | 18/223513 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/0058 (20210501) H02M 3/335 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240023348 | LUNT, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); Board of Regents of the Nevada system of Higher Educationon behalf of the University of Nevada, Reno (Reno, Nevada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Royal LUNT, III (Williamston, Michigan); Matthew BATES (East Lansing, Michigan); Ryan J. MALONE (Edmonton, Canada); Wesley A. CHALIFOUX (Edmonton, Canada) |
| ABSTRACT | A photovoltaic device includes a substrate, a first electrode on a surface of the substrate, a second electrode, and a first photoactive layer between the first electrode and the second electrode. The first photoactive layer includes graphene nanoribbons (GNRs). |
| FILED | Monday, July 17, 2023 |
| APPL NO | 18/222944 |
| CURRENT CPC | Organic electric solid-state devices H10K 30/20 (20230201) H10K 30/50 (20230201) Original (OR) Class H10K 85/211 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20240016453 | Field et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana); The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tyler C. Field (West Lafayette, Indiana); Samantha Marie Neeno (West Lafayette, Indiana); Robert Merton Stwalley, III (Lafayette, Indiana); Allan P. Schinkel (West Lafayette, Indiana); Jay S. Johnson (West Lafayette, Indiana) |
| ABSTRACT | Devices and methods for monitoring internal physiological parameters of animals. Such a device and method makes use of a housing configured for implantation in an animal, and at least first and second arms pivotally coupled to the housing to have a collapsed configuration and a deployed configuration, wherein the first and second arms are alongside the housing and approximately parallel to the longitudinal axis in the collapsed configuration, expanded outward away from the housing and not parallel to the longitudinal axis in the deployed configuration, and biased toward the deployed configuration. Sensors are associated with the housing for collecting physiological parameters of the animal. The device is further equipped with a wireless transmitter for wirelessly transmitting outputs of the sensors to a receiver while the housing is implanted internally within the animal and the receiver is located externally of the animal. |
| FILED | Wednesday, July 12, 2023 |
| APPL NO | 18/351037 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0031 (20130101) A61B 5/6867 (20130101) Original (OR) Class A61B 5/6882 (20130101) A61B 5/14552 (20130101) A61B 7/023 (20130101) A61B 2503/40 (20130101) A61B 2560/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018095 | LEW et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | HELEN N. LEW (WYNNEWOOD, Pennsylvania); KUN HUANG (CONSHOHOCKEN, Pennsylvania); RICHARD D. ASHBY (GLENSIDE, Pennsylvania); XUETONG FAN (NORTH WALES, Pennsylvania) |
| ABSTRACT | Composition and methods for killing microorganisms using antimicrobial epoxy polymers and epoxy polymer curing agents are described. Compositions containing at least one compound of formula I where R1 is a phenolic group (e.g., simple phenol, creosote, thymol, or carvacrol), and where R2 is a polyamine (e.g., ethylenediamine (EDA), diethylenetriamine (DETA), triethylenetetramine (TETA), tetraethylenepentamine (TEPA), hexamethylenediamine (HDA)); and optionally a carrier; the compositions may additionally contain at least one epoxy resin. Methods for killing microorganisms involving contacting the microorganisms with an effective microorganism killing amount of the above composition. |
| FILED | Thursday, September 28, 2023 |
| APPL NO | 18/476728 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/50 (20130101) Acyclic or Carbocyclic Compounds C07C 231/02 (20130101) Original (OR) Class C07C 237/10 (20130101) Heterocyclic Compounds C07D 233/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020634 | Bao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Auburn University (Auburn, Alabama) |
| ASSIGNEE(S) | Auburn University (Auburn, Alabama) |
| INVENTOR(S) | Yin Bao (Auburn, Alabama); James L. Johnson (Auburn, Alabama); Bobby Bradford (Auburn, Alabama); Rafael Bidese Puhl (Auburn, Alabama) |
| ABSTRACT | The present tree seedling inventory system includes both a mobile platform used to obtain images of seedlings and a tree seedling inventory system to count the seedlings. A recurrent neural network can receive processed imaging data and utilize a model to accurately count the seedlings as the mobile platform passes along a seedling bed. The system may also provide additional accurate seedling quality data about the seedlings, such as shoot height, root collar diameter, and needle coloration. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/174350 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/087 (20130101) Original (OR) Class G06Q 50/02 (20130101) Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 2207/20084 (20130101) G06T 2207/20132 (20130101) G06T 2207/30188 (20130101) G06T 2207/30242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020774 | BASSO |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bruno BASSO (East Lansing, Michigan) |
| ABSTRACT | Nitrogen-based agricultural crop fertilizers are known to be a source of N2O emission, due to various direct and indirect processes. For example microbial activity, volatilization from spraying, volatilization from evaporative processes, and the like cause N2O emission. From a standpoint of environmental science, various “precision conservation” methods and adaptations to nitrogen fertilizer application can mitigate these processes. By reducing these processes, and thereby reducing greenhouse gas emissions, carbon credit programs can be leveraged. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 18/256891 |
| CURRENT CPC | Planting; Sowing; Fertilising A01C 21/005 (20130101) A01C 21/007 (20130101) A01C 23/047 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06313 (20130101) G06Q 30/018 (20130101) G06Q 50/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20240016648 | Arsiwala |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohammed Ali Arsiwala (Northville, Michigan) |
| ABSTRACT | A splint for use on a forearm, a wrist, and a hand of a user, including a rigid shell assembly with dorsal and a volar shell bodies, the dorsal and volar shell bodies each including a forearm portion, a wrist portion, and a hand portion. The dorsal and volar shell bodies are configured to releasably receive the forearm, wrist, and hand of the user therebetween. A dorsal compressible assembly and a volar compressible assembly extend along the inner surfaces of the dorsal and volar shell bodies, respectively. The volar compressible assembly includes an inflatable forearm bladder, an inflatable wrist bladder, and an inflatable hand bladder, each of which includes a valve to allow each of the inflatable bladders to be inflated independently of the other inflatable bladders. |
| FILED | Wednesday, July 12, 2023 |
| APPL NO | 18/350934 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/05816 (20130101) A61F 5/05866 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240016792 | Suo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Z. Suo (Kansas City, Missouri) |
| ABSTRACT | Provided are methods for delaying or preventing onset of progressive memory decline by administering a muscarinic M2 receptor blocking compound to patients identified as at risk of developing a condition characterized by progressive memory decline, prior to onset of the condition. |
| FILED | Monday, September 25, 2023 |
| APPL NO | 18/372662 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/4545 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240018247 | Tomlinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MUSC Foundation for Research Development (Charleston, South Carolina); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); Universitat De Barcelona (Barcelona, Spain) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Tomlinson (Charleston, South Carolina); Ali Alawieh (Atlanta, Georgia); Pablo Engel (Barcelona, Spain) |
| ABSTRACT | The present invention describes compositions and methods for targeting complement inhibition to sites of p-selectin expression, and compositions for inhibiting p-selectin and complement. |
| FILED | Wednesday, August 30, 2023 |
| APPL NO | 18/458214 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Peptides C07K 14/70596 (20130101) C07K 16/2854 (20130101) Original (OR) Class C07K 2317/565 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020833 | Ovchinnikova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Olga S. Ovchinnikova (Knoxville, Tennessee); Jacob D. Hinkle (Oak Ridge, Tennessee); Inzamam Haque (Knoxville, Tennessee); Debangshu Mukherjee (Knoxville, Tennessee) |
| ABSTRACT | Systems, methods and programs including machine learning techniques which can predict a spectral image directly from an optical image of a patient's tissue sample using a first model. There may be different first models for different cancers. Each first model may be trained by using a plurality of pairs of images from different samples, respectively, where each image in a respective pair may be obtained via different imaging modalities. The systems, methods and programs may also include machine learning techniques which can predict cancer labels from the predicted spectral image using a second model. There may be different second models for different cancers. Each second model may be trained using multiple spectral images and corresponding manually input cancer labels. |
| FILED | Friday, June 23, 2023 |
| APPL NO | 18/340306 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 7/0012 (20130101) Original (OR) Class G06T 2200/24 (20130101) G06T 2207/10056 (20130101) G06T 2207/20016 (20130101) G06T 2207/20081 (20130101) G06T 2207/30081 (20130101) G06T 2207/30088 (20130101) G06T 2207/30096 (20130101) G06T 2207/30204 (20130101) Image or Video Recognition or Understanding G06V 10/774 (20220101) G06V 10/7715 (20220101) G06V 20/698 (20220101) G06V 2201/03 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240017487 | Townsend et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sidus Space, Inc. (Merritt Island, Florida) |
| ASSIGNEE(S) | Sidus Space, Inc. (Merritt Island, Florida) |
| INVENTOR(S) | Ivan Townsend (Merritt Island, Florida); Robert Mueller (Merritt Island, Florida); Nathan Gelino (Merritt Island, Florida); Jonathan Smith (Merritt Island, Florida); Matthew Nugent (Merritt Island, Florida); Andrew Nick (Merritt Island, Florida); Jason Schuler (Merritt Island, Florida); Bradley Buckles (Merritt Island, Florida) |
| ABSTRACT | A three-dimensional print head apparatus including a hopper, a nozzle, a barrel, and a heating system. The apparatus may further include a fume extraction system and a dry air purge system. The hopper may have a cavity and a lower aperture. The nozzle may have an upper aperture and a lower aperture. The heating system may be positioned along the barrel, and the dry air purge system may be in fluid communication with the hopper. |
| FILED | Monday, July 24, 2023 |
| APPL NO | 18/357383 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/209 (20170801) Original (OR) Class B29C 64/329 (20170801) B29C 64/364 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017488 | Townsend et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sidus Space, Inc. (Merritt Island, Florida) |
| ASSIGNEE(S) | Sidus Space, Inc. (Merritt Island, Florida) |
| INVENTOR(S) | Ivan Townsend (Merritt Island, Florida); Robert Mueller (Merritt Island, Florida); Nathan Gelino (Merritt Island, Florida); Jonathan Smith (Merritt Island, Florida); Matthew Nugent (Merritt Island, Florida); Andrew Nick (Merritt Island, Florida); Jason Schuler (Merritt Island, Florida); Bradley Buckles (Merritt Island, Florida) |
| ABSTRACT | A three-dimensional print head apparatus comprising a hopper, a nozzle, a barrel, a heating system, a fume extraction system, a dry air purge system, and an agitator. The hopper may having a cavity and may have a lower aperture. The nozzle may have an upper aperture and may have a lower aperture. The heating system may be positioned along at least a portion of the barrel, which may defined a heated zone of the barrel. The dry air purge system may be in fluid communication with the hopper. The agitator may have at least one paddle. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/474316 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/209 (20170801) Original (OR) Class B29C 64/329 (20170801) B29C 64/364 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240019240 | BATHEL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brett F. BATHEL (Yorktown, Virginia); Joshua M. WEISBERGER (Newport News, Virginia) |
| ABSTRACT | An adjustable beam directing optical system for a focused laser differential interferometer (FLDI) instrument according to various aspects of the present technology may include optical half waveplate to achieve an incident linear polarization orientation with equal components of laser intensity aligned to the vertical and horizontal axis of the optical system, and an optical prism for splitting these components of an incident laser beam into two orthogonally-polarized beams equally about an optical axis of the FLDI instrument. A series of beam realignment devices positioned downstream of the optical prism are configured to selectively direct each beam to a predetermined location. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/375108 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02001 (20130101) G01B 9/02015 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 5/3083 (20130101) G02B 7/003 (20130101) G02B 7/1805 (20130101) G02B 27/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240021428 | Greer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Harold Frank Greer (Los Angeles, California); Rehan Kapadia (Los Angeles, California); Debargyha Sarkar (Pasadena, California) |
| ABSTRACT | A method for processing a surface, comprising obtaining a substrate comprising an epitaxially grown semiconductor; reacting a surface of the semiconductor and/or a surface of a dielectric layer on the semiconductor, with a reactant comprising a gas or a plasma, to form a reactive layer on the dielectric layer and/or the semiconductor, wherein the reactive layer comprises a chemical compound including the reactant and elements of the dielectric layer or the semiconductor; and processing (e.g., removing, modifying, and/or chemically reducing) the reactive layer, wherein the processing at least smoothens, controls defects at, improves the electrical properties of, or the optical properties of, the surface |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/352175 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) Original (OR) Class H01L 21/7684 (20130101) H01L 21/823871 (20130101) H01L 23/53238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20240017897 | Steed |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Darren Jay Steed (Egg Harbor Township, New Jersey) |
| ABSTRACT | The present application is directed to a packaging for a powdered explosive-detection training aid which may include first and second opposing flexible sheets heat sealed together along less than a periphery thereof and defining a storage compartment therebetween, wherein an unsealed portion of the periphery defines an opening to the storage compartment, wherein at least a portion of the first opposing flexible sheet is a semipermeable material permeable to a vapor emitted from the powdered explosive-detection training aid, with the second opposing flexible sheet being impermeable to the powdered explosive-detection training aid vapor; and a sealing member, wherein the sealing member is secured to the first opposing flexible sheet and, in a closing position, covers the semipermeable portion of the first opposing flexible sheet. |
| FILED | Thursday, September 21, 2023 |
| APPL NO | 18/371288 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 15/02 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 33/01 (20130101) B65D 75/30 (20130101) Original (OR) Class B65D 85/70 (20130101) B65D 2565/388 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/132 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 8/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020368 | Vemury |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | Systems and methods for providing exception failover augmented, homomorphic encrypted (HE) distributing, end-to-endpoint persistent encryption, and distributed HE domain non-decrypting, privacy-protective biometric processing are provided. Some configurations may include generating HE biometric feature data, based on homomorphic encrypting the biometric feature data. Some configurations determine an exception status of the HE biometric feature data between exception and non-exception. Systems and methods may include performing a HE domain, non-decrypting biometric classifying of the HE biometric feature data. |
| FILED | Tuesday, June 13, 2023 |
| APPL NO | 18/209332 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/32 (20130101) Original (OR) Class G06F 21/602 (20130101) G06F 21/6245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20240020253 | Sharma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shruti Sharma (Beaverton, Oregon); Robert Pawlowski (Beaverton, Oregon); Fabio Checconi (Fremont, California); Jesmin Jahan Tithi (San Jose, California) |
| ABSTRACT | Systems, apparatuses and methods may provide for technology that detects a plurality of sub-instruction requests from a first memory engine in a plurality of memory engines, wherein the plurality of sub-instruction requests are associated with a direct memory access (DMA) data type conversion request from a first pipeline, wherein each sub-instruction request corresponds to a data element in the DMA data type conversion request, and wherein the first memory engine is to correspond to the first pipeline, decodes the plurality of sub-instruction requests to identify one or more arguments, loads a source array from a dynamic random access memory (DRAM) in a plurality of DRAMs, wherein the operation engine is to correspond to the DRAM, and conducts a conversion of the source array from a first data type to a second data type in accordance with the one or more arguments. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/477787 |
| CURRENT CPC | Electric Digital Data Processing G06F 13/28 (20130101) Original (OR) Class G06F 2213/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020569 | Inoue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ken Inoue (Elmsford, New York); MAIKA TAKITA (Croton on Hudson, New York); Antonio Corcoles-Gonzalez (Mount Kisco, New York); Scott Douglas Lekuch (New York, New York) |
| ABSTRACT | One or more systems, devices, computer program products and/or computer-implemented methods of use provided herein relate to a process to dynamically determine a threshold for determining a state of a qubit and apply the threshold for operating a pulse to de-excite the qubit. A system can comprise a memory that stores computer executable components, and a processor that executes the computer executable components stored in the memory, wherein the computer executable components can comprise a decision component that is configured to determine a threshold of a plurality of thresholds to apply to measurement of a state of a qubit based on a probability distribution of state of the qubit, wherein a measurement at one side of the threshold is representative of the qubit being in the ground state, and wherein a measurement at another side of the threshold is representative of the qubit being in an excited state. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/813082 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) G06N 10/70 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20240016830 | Golobish et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CytoSorbents, Inc. (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Golobish (Princeton, New Jersey); Maryann Gruda (Yardley, Pennsylvania); Tamaz Guliashvili (Philadelphia, Pennsylvania); Pamela O'Sullivan (Manalapan, New Jersey); Andrew Scheirer (Hoboken, New Jersey); Vi Dan (East Brunswick, New Jersey); Wei-Tai Young (Hillsborough, New Jersey); Vincent Capponi (Lawrenceville, New Jersey); Phillip Chan (Cherry Hill, New Jersey) |
| ABSTRACT | The invention concerns biocompatible polymer systems comprising at least one polymer with a plurality of pores, said polymer comprising a sulfonic acid salt functionality designed to adsorb a broad range of protein based toxins from less than 0.5 kDa to 1,000 kDa and positively charged ions including but not limited to potassium. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345683 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/795 (20130101) Original (OR) Class A61K 47/20 (20130101) A61K 47/26 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3679 (20130101) A61M 5/165 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/264 (20130101) B01J 20/267 (20130101) B01J 20/28069 (20130101) B01J 39/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240017311 | Quigley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (North Potomac, Maryland) |
| ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system are provided herein. According to some aspects of the technology, there is provided site-level control methods for globally controlling one or more wells based on one or more characteristics of aggregate landfill gas collected from a plurality of wells at a gas output. According to some aspects of the technology, there is provided well-level control methods for locally controlling a first well based on or more characteristics of landfill gas collected from the first well. According to further aspects of the technology, there is provided hybrid control methods for making adjustments to a respective well based on both site-level and well-level control methods. |
| FILED | Monday, April 10, 2023 |
| APPL NO | 18/132753 |
| CURRENT CPC | Reclamation of Contaminated Soil B09C 1/005 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/00 (20130101) E21B 43/12 (20130101) E21B 47/06 (20130101) E21B 49/0875 (20200501) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) G01N 33/0044 (20130101) G01N 33/0047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20240020603 | LEVIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mary Beth LEVIN (Washington, District of Columbia); Nicholas John SUCICH (Manassas, Virginia); Qiao ZHANG (Herndon, Virginia) |
| ABSTRACT | Techniques for detecting and remediating logistical operational delays are presented. The techniques can include: obtaining electronic operational feedback associated with logistics in a geographical region, where the electronic operational feedback includes at least one of: customer email messages, customer phone messages, web-based customer reviews, delivery delay times, social media communication issue resolution times, or employment satisfaction ratings; generating a heatmap representing the electronic operational feedback for the geographical region, where an operational issue hotspot corresponding to a logistical node in the geographic region is displayed; and remediating an operation issue at the logistical node in the geographic region that corresponds to the operational issue hotspot. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/352747 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/067 (20130101) G06Q 10/0833 (20130101) G06Q 10/06312 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240020888 | Simpson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan J. Simpson (Vienna, Virginia) |
| ABSTRACT | This application relates to a system for compressing captured images. The system may include an image capturing device configured to continuously capture images, for example, of a location, or frame, or field of view, and convert the captured images respectively into a plurality of sets of digital data, each of the plurality of sets of digital data including at least two consecutive rows of digital data. The system may also include a processor circuit configured to combine the at least two sets of the plurality of sets of digital data to generate a pre-compression set of digital data and simultaneously compress the pre-compression set of digital data simultaneously or together in a single compression operation. |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/362298 |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/14 (20130101) Image Data Processing or Generation, in General G06T 7/13 (20170101) G06T 9/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Central Intelligence Agency (CIA)
| US 20240021873 | WIDSTROM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | High Performance Air Stable Solid Polymer Electrolyte (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Matthew D. WIDSTROM (Ellicott City, Maryland); Peter KOFINAS (N. Bethesda, Maryland); Arthur V. CRESCE (Beltsville, Maryland); Kang XU (Potomac, Maryland) |
| ABSTRACT | The present invention is directed to aqueous solid polymer electrolytes that comprise a lithium salt and battery cells comprising the same. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies. |
| FILED | Thursday, April 06, 2023 |
| APPL NO | 18/131745 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/505 (20130101) H01M 4/5825 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20240018041 | CEYLAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Halil CEYLAN (Ames, Iowa); Alireza SASSANI (Ames, Iowa); Hesham ABDUALLA (Champaign, Illinois); Sunghwan KIM (Ames, Iowa); Ali ARABZADEH (Ames, Iowa); Peter C. TAYLOR (Ames, Iowa); Kasthurirangan GOPALAKRISHNAN (Minneapolis, Minnesota) |
| ABSTRACT | The present application relates to a concrete pre-mix composition comprising a cementitious material and a plurality of conductive carbon microfibers mixed with said cementitious material, where said conductive carbon microfibers are present in the concrete pre-mix composition in an amount such that, when said concrete pre-mix composition is hydrated to form concrete and cured, the conductive carbon microfibers are dispersed in the cured concrete in an amount of 0.75% to 2.00% of total mass of the concrete. The present application further relates to a concrete composition, a method of producing an electrically conductive concrete composition, an electrically conductive cured concrete form, and a system for heating pavement. |
| FILED | Tuesday, July 25, 2023 |
| APPL NO | 18/358500 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/386 (20130101) Original (OR) Class C04B 22/085 (20130101) C04B 24/383 (20130101) C04B 28/04 (20130101) C04B 40/0042 (20130101) C04B 2111/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20240019637 | Peng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yiwei Peng (Milpitas, California); Yuan Yuan (Milpitas, California); Zhihong Huang (Milpitas, California) |
| ABSTRACT | Examples described herein relate to an optical resonating device. The optical resonating device includes a primary waveguide, a microring resonator, and a microring resonator photodiode. The primary waveguide allows a passage of an optical signal. The microring resonator is formed adjacent to the primary waveguide to couple therein a portion of the optical signal passing through the primary waveguide. Furthermore, the microring resonator photodiode is formed adjacent to the microring resonator to measure an intensity of the portion of the optical signal coupled into the microring resonator. |
| FILED | Thursday, July 14, 2022 |
| APPL NO | 17/812554 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) G02B 6/1225 (20130101) G02B 6/29338 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20240016828 | WANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of North Texas Health Science Center (Fort Worth, Texas) |
| ASSIGNEE(S) | University of North Texas Health Science Center (Fort Worth, Texas) |
| INVENTOR(S) | Yu-Chieh WANG (Fort Worth, Texas); Victor J.T. LIN (Fort Worth, Texas); Ashwini Ashwini ZOLEKAR (Fort Worth, Texas); Kyle A. EMMITTE (Aledo, Texas); Nigam M. MISHRA (Fort Worth, Texas); Jin LIU (Dallas, Texas) |
| ABSTRACT | In one aspect, the present disclosure provides GlcNAc-Asn analogs of the formula: wherein the variables are as defined herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of using the compounds disclosed herein. Additionally, the present disclosure also provides methods of treating cancer comprising inhibiting NGLY1. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/454671 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 309/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20240020524 | Vo |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America As Represented By The Director Of The National Geospatial-Intelligence (Springfield, Virginia) |
| ASSIGNEE(S) | The United States of America As Represented jBy The Director Of The National Geospatial-Intelligence (Springfield, Virginia) |
| INVENTOR(S) | Garret Vo (Gaithersburg, Maryland) |
| ABSTRACT | Systems and methods for automatically labeling documents and identifying mis-labeled documents at scale. Documents are pre-processed, divided into training and testing sets, and processed. After processing, a network graph is formed, the documents are embedded using a graph convolutional neural network, and the embedded documents are enhanced using a bag-of-words appending technique. The documents are then labeled using a neural network with a focal loss function. Optionally, the focal loss function can be used to calculate a probability value for each label. The probability values are used to identify mislabeled documents. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/813094 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/93 (20190101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
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THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, January 18, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240118.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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