FedInvent™ Patent Applications
Application Details for Thursday, February 15, 2024
This page was updated on Tuesday, June 18, 2024 at 02:14 PM GMT
Department of Health and Human Services (HHS)
20240049828 — Wearable Hydraulic System And Shock Absorbing Device For Reducing Forces Due To Impact
| US 20240049828 | Allison et al. |
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| FUNDED BY |
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| APPLICANT(S) | Savior Brain Inc. (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Daniel Allison (Lake Oswego, Oregon); Christoph Eduard Mack (Seattle, Washington); Gordon Lee Avery, JR. (Arlington, Virginia); Ryan Gundling (Staunton, Virginia); Ryan Long (Staunton, Virginia) |
| ABSTRACT | A novel liquid-based system and shock absorber for reducing the forces experienced during high-energy impacts is provided. Individual shock absorbing devices can be used in parallel or in series to create a tunable network that is based on the specific energy absorption requirements for each application. Each shock absorbing device consists of a flexible, primary fluid-filled reservoir that, when impacted, ejects the liquid at high pressure through an array of orifices into a secondary flexible, low-pressure collection reservoir, where it is temporarily stored before the liquid returns to the primary reservoir where the device is ready for the next impact. Optionally, the shock absorbing device may be a single-use device, where the liquid ejects from but does not return to the reservoir. |
| FILED | Wednesday, July 12, 2023 |
| APPL NO | 18/221107 |
| CURRENT CPC | Hats; Head Coverings A42B 3/121 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050219 | Genin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri); Columbia University (New York, New York) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); Columbia University (New York, New York) |
| INVENTOR(S) | Guy Genin (St. Louis, Missouri); Ethan Hoppe (St. Louis, Missouri); Dong Hwan Yoon (St. Louis, Missouri); Stavros Thomopoulos (New York, New York); Iden Kurtaliaj (NY, New York); Liana Tedesco (NY, New York); David Kovacevic (NY, New York); Victor Birman (St. Louis, Missouri); Lester Smith (Indianapolis, Indiana); Leesa Galatz (St. Louis, Missouri); William Levine (New York, New York) |
| ABSTRACT | Devices and methods for joining a first and second tissue in a patient are disclosed that include a base with a plurality of recurved tines oriented to a tine axis and extending from a first surface of the base. The tines provide unidirectional traction of the first tissue along the tine axis toward the first surface. The first tissue is secured to the first surface of the device at the plurality of recurved tines and the second tissue is secured to the device at a second surface opposite the first surface to join the first and second tissues. |
| FILED | Monday, October 05, 2020 |
| APPL NO | 17/766503 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0077 (20130101) A61F 2/0811 (20130101) Original (OR) Class A61F 2002/0829 (20130101) A61F 2002/0858 (20130101) A61F 2002/0888 (20130101) A61F 2210/0004 (20130101) A61F 2220/0016 (20130101) A61F 2230/0019 (20130101) A61F 2250/0028 (20130101) A61F 2250/0058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050251 | Bly et al. |
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| FUNDED BY |
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| APPLICANT(S) | ZENFLOW, INC. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Austin Michael Bly (San Clemente, California); Marcel Song Sicotte (San Francisco, California); Shreya Mehta (San Francisco, California); William Martin Belef (San Francisco, California); Nicholas Damiano (San Francisco, California) |
| ABSTRACT | Systems, devices, and methods are provided for the delivery of an implant into the prostatic urethra. Embodiments of delivery systems can include a delivery device for insertion into the patient and a proximal control device for use in controlling release of the implant from the delivery device. |
| FILED | Wednesday, October 11, 2023 |
| APPL NO | 18/378940 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/005 (20130101) A61B 1/05 (20130101) A61B 1/00082 (20130101) A61B 1/00087 (20130101) A61B 1/307 (20130101) A61B 1/0676 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/966 (20130101) Original (OR) Class A61F 2/9517 (20200501) A61F 2002/047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050369 | Fang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois); THE UNIVERSITY OF UTAH (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yun Fang (Chicago, Illinois); Matthew V. Tirrell (Chicago, Illinois); Yan-Ting Shiu (Salt Lake City, Utah) |
| ABSTRACT | This disclosure relates to compositions and methods for treating vascular disorders, including, for example, arteriovenous fistula (AVF) failure, stenosis, restenosis, and atherosclerosis. |
| FILED | Monday, October 05, 2020 |
| APPL NO | 17/766318 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) Original (OR) Class A61K 31/7105 (20130101) A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 47/42 (20130101) A61K 47/183 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050386 | DORN, II |
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| FUNDED BY |
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| APPLICANT(S) | Gerald W. DORN, II (Sullivan's Island, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gerald W. DORN, II (Sullivan's Island, South Carolina) |
| ABSTRACT | Compositions capable of promoting mitofusin activation may include a mitofusin activator having a structure represented by any stereoisomer thereof, or any pharmaceutically acceptable salt thereof. G is N or CH, and A is an optionally substituted 5- or 6-membered cycloalkyl or heterocycloalkyl ring. X is (CH2)3,OCH2CH2, CH2OCH2, CH2CH2O, Cyc, CH2Cyc, NR1 (CH2)3,NR1OCH2CH2, NR1CH2OCH2, NR1CH2CH2O, or NR1Y, R1 is H or C1-C6 alkyl, and Cyc is 1,2-cyclopropyl, 1,2-cyclobutyl, 1,3-cyclobutyl, 1,2-cyclopentyl, 1,3-cyclopentyl, 1,2-cyclohexyl, 1,3-cyclohexyl, or 1,4-cyclohexyl. Z is (CH2)n or (CH2)n |
| FILED | Tuesday, April 04, 2023 |
| APPL NO | 18/547996 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) Original (OR) Class A61K 31/445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050392 | Costello et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF THE COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James C. Costello (Denver, Colorado); Dan Theodorescu (Los Angeles, California); Robert Jones (Denver, Colorado); Tahlita C.M. Zuiverloon (The Hague, Netherlands); Andrew Goodspeed (Denver, Colorado) |
| ABSTRACT | Embodiments of the instant disclosure relate to novel methods and compositions for treating tumors resistant to platinum-based chemotherapy. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one M1 aminopeptidase inhibitor in combination with at least one platinum-based chemotherapeutic agent separately or in a combination therapy. In some embodiments, methods of treating tumors disclosed herein can include screening and/or selecting a subject suitable for treatment based on NPEPPS gene or protein expression in the tumor to be treated. In other embodiments, methods of treating tumors can include administering a composition including a combination of at least one M1 aminopeptidase inhibitor and at least one platinum-based chemotherapeutic agent. In certain embodiments, compositions disclosed herein can include at least tosedostat and carboplatin. |
| FILED | Thursday, August 24, 2023 |
| APPL NO | 18/237705 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/216 (20130101) Original (OR) Class A61K 31/282 (20130101) A61K 31/475 (20130101) A61K 31/519 (20130101) A61K 31/704 (20130101) A61K 31/7068 (20130101) A61K 33/243 (20190101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050420 | Nauli et al. |
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| FUNDED BY |
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| APPLICANT(S) | Chapman University (Orange, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Surya Nauli (Orange, California); Rajasekharreddy Pala (Orange, California) |
| ABSTRACT | Disclosed herein are nanoparticulate formulations of pharmaceutical agents and methods of treating kidney diseases with the formulation. |
| FILED | Monday, July 17, 2023 |
| APPL NO | 18/222775 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5146 (20130101) A61K 31/436 (20130101) A61K 31/445 (20130101) Original (OR) Class A61K 47/551 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050426 | Gack et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michaela Gack (Cleveland, Ohio); Michiel van Gent (Cleveland, Ohio) |
| ABSTRACT | Provided herein are compositions, systems, and methods treating latent viral infection with an NMD inhibitor (e.g. to reactive the latent virus to lytic virus), in combination with an anti-viral agent. In certain embodiments, the latent viral infection is caused by EBV or KSHV. In other embodiments, cancer (e.g., caused by the virus) is treated by further administering an anti-cancer agent, such as an immunomodulatory agent. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 18/546245 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/498 (20130101) A61K 31/522 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/22 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050436 | EL-REMESSY et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States GOVERNMENT As Represented By The Department of Veterans Affairs (Washington, District of Columbia); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (STANFORD, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | AZZA EL-REMESSY (Martinez, Georgia); FRANK LONGO (Menlo Park, California) |
| ABSTRACT | Disclosed are methods of treating an ocular disease associated with retinal ischemic injury in a subject comprising administering to the subject a p75NTR modulator, a MSC comprising decreased p75NTR expression or activity or a MSC secretome collected from a MSC comprising decreased p75NTR expression or activity. Disclosed are methods of treating late stage diabetes in a subject comprising administering to the subject in need thereof a p75NTR modulator, a MSC comprising decreased p75NTR expression or activity or a MSC secretome collected from a MSC comprising decreased p75NTR expression or activity. |
| FILED | Friday, October 20, 2023 |
| APPL NO | 18/491249 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5375 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 38/1866 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/02 (20180101) A61P 13/12 (20180101) A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050440 | Palladino et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh- Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Michael John Palladino (Pittsburgh, Pennsylvania); Stacy Lynn Hrizo (Cranberry Township, Pennsylvania); Andreas Vogt (Pittsburgh, Pennsylvania) |
| ABSTRACT | Triosephosphate isomerase deficiency (TPI Df) is a devastating childhood degenerative disease for which there are currently no treatments. Pathogenesis of this disease is driven by mutations that destabilize the TPI protein. A genome-wide RNAi screen in Drosophila to identify regulators of TPI stability is described. The screen identified 25 proteins that are critical to TPI stability, each of which has a human ortholog. Methods of promoting TPI protein stability and treating TPI Df in a subject by administering a therapeutically effective amount of an agent that inhibits expression or activity of one of the identified regulators are described. Also described is a method for the identification of agents capable of promoting stability of mutant TPI. Methods for treating a subject who has TPI Df by administering an agent that promotes stability of mutant TPI is also described. |
| FILED | Thursday, December 30, 2021 |
| APPL NO | 18/269260 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/357 (20130101) A61K 31/5377 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/90 (20130101) Enzymes C12Y 503/01001 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050509 | Xing et al. |
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| FUNDED BY |
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| APPLICANT(S) | KUALITY HERBCEUTICS LLC (Gainesville, Florida) |
| ASSIGNEE(S) | KUALITY HERBCEUTICS LLC (Gainesville, Florida) |
| INVENTOR(S) | Chengguo Xing (Gainesville, Florida); Stephen Hecht (St. Paul, Minnesota); Junxuan Lu (Hershey, Pennsylvania); Pramod Upadhyaya (Atlanta, Georgia); Sharon Murphy (St. Paul, Minnesota); Pablo Leitzman (Minneapolis, Minnesota); Sreekanth Narayanapillai (St. Paul, Minnesota); Silvia Balbo (St. Paul, Minnesota) |
| ABSTRACT | Certain embodiments of the invention provide a composition comprising at least two compounds selected from the group consisting of dihydromethysticin, methysticin, dihydrokavain, kavain, desmethoxyyangonin and 11-methoxyyangonin, wherein the composition is substantially free of flavokawain B. Certain embodiments of the invention also provide a method for treating or preventing cancer in a mammal (e.g., a human) in need of such treatment comprising, administering to the mammal a carrier and a compound selected from the group consisting of dihydromethysticin, methysticin, dihydrokavain, kavain, desmethoxyyangonin and 11-methoxyyangonin, wherein the compound is substantially free of other kava extract components. |
| FILED | Tuesday, February 21, 2023 |
| APPL NO | 18/112385 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/353 (20130101) A61K 31/366 (20130101) A61K 36/67 (20130101) Original (OR) Class A61K 2236/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050517 | DAGGETT et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Valerie DAGGETT (Seattle, Washington); Alissa BLEEM (Seattle, Washington) |
| ABSTRACT | Disclosed herein are α-sheet peptides and their use for treating a bacterial infection and/or limiting bacterial biofilm formation. |
| FILED | Friday, October 20, 2023 |
| APPL NO | 18/491099 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/70 (20130101) A61K 38/02 (20130101) A61K 38/16 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/22 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 2202/24 (20130101) A61L 2300/25 (20130101) A61L 2300/252 (20130101) A61L 2300/404 (20130101) A61L 2300/606 (20130101) A61L 2420/02 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 41/00 (20180101) Peptides C07K 16/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050522 | Schwendeman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anna Schwendeman (Ann Arbor, Michigan); Hongliang He (Ann Arbor, Michigan); Sang Yeop Kim (Ann Arbor, Michigan); Xiang-An Li (Lexington, Kentucky) |
| ABSTRACT | Accordingly, the present invention relates compositions comprising synthetic HDL (sHDL) nanoparticles, methods for synthesizing such sHDL nanoparticles, as well as systems and methods utilizing such sHDL nanoparticles (e.g., in diagnostic and/or therapeutic settings). In particular, the present invention provides compositions comprising sHDL nanoparticles for purposes of preventing, attenuating, and/or treating sepsis and sepsis related disorders in a subject, conditions and symptoms caused by a viral infection (e.g., COVID-19)) in a subject, and conditions and symptoms caused by thrombosis in a subject. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 18/266542 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 31/573 (20130101) A61K 31/675 (20130101) A61K 31/4706 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/24 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050524 | Park et al. |
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| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyung-Won Park (Houston, Texas); Joanna Jankowsky (Houston, Texas) |
| ABSTRACT | Aspects of the present disclosure are directed to compositions and methods for treating a subject having a neurodegenerative disorder, disease, or condition. Certain aspects relate to treatment with a therapeutically effective amount of a composition comprising a vector encoding an Aβ peptide variant. Further aspects relate to methods of inhibiting aggregation of endogenous Aβ peptide in vivo by contacting at least one such peptide with a therapeutically effective amount of an expressed Aβ peptide variant from a vector encoding the Aβ peptide variant, said vector in a composition. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 18/267980 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1716 (20130101) Original (OR) Class A61K 48/0041 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050529 | Kipnis et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Kipnis (Charlottesville, Virginia); Antoine Louveau (Charlottesville, Virginia); Sandro Da Mesquita (Charlottesville, Virginia) |
| ABSTRACT | In some embodiments herein, methods, compositions, and uses for modulating lymphatic vessels of the central nervous system are described. In some embodiments, methods, compositions, or uses for treating, preventing, or ameliorating symptoms of a neurological disease comprise increasing flow via meningeal lymphatic vessels are described. |
| FILED | Tuesday, October 06, 2020 |
| APPL NO | 17/766479 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1825 (20130101) Original (OR) Class A61K 38/1866 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050554 | Boyington et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, department of Health and Human Servic (Bethesda, Maryland) |
| INVENTOR(S) | Jeffrey C. Boyington (Clarksburg, Maryland); Barney S. Graham (Smyrna, Georgia); John R. Mascola (Rockville, Maryland); Hadi M. Yassine (Doha, Qatar); Kizzmekia S. Corbett (Wheaton, Maryland); Syed M. Moin (Laurel, Maryland); Lingshu Wang (North Potomac, Maryland); Masaru Kanekiyo (Chevy Chase, Maryland) |
| ABSTRACT | Vaccines that elicit broadly protective anti-influenza antibodies. The vaccines comprise nanoparticles that display HA trimers from Group 2 influenza virus on their surface. The nanoparticles are fusion proteins comprising a monomeric subunit (e.g., ferritin) joined to stabilized stem regions of Group 2 influenza virus HA proteins. The fusion proteins self-assemble to form the HA-displaying nanoparticles. Also provided are fusion proteins, and nucleic acid molecules encoding such proteins, and assays using nanoparticles of the invention to detect anti-influenza antibodies. |
| FILED | Friday, October 20, 2023 |
| APPL NO | 18/491193 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 14/005 (20130101) C07K 14/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050561 | FOX |
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| FUNDED BY |
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| APPLICANT(S) | ACCESS TO ADVANCED HEALTH INSTITUTE (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Bradford FOX (Sumner, Washington) |
| ABSTRACT | This disclosure describes the use of solanesol as an adjuvant in vaccine compositions, as well as related prophylactic and therapeutic methods. Solanesol may be used to replace squalene in vaccine compositions with similar or superior immunostimulatory effects. Solanesol, which is solid at room temperature, may be formulated for use in vaccine compositions by heating above its melting temperature in an aqueous solution to form a dispersion. |
| FILED | Saturday, October 16, 2021 |
| APPL NO | 18/269284 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/145 (20130101) A61K 47/22 (20130101) A61K 2039/55566 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050578 | Spiegel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); David Caianiello (New Haven, Connecticut) |
| ABSTRACT | Described herein is a bi-functional compound for removing macrophage migration inhibitory factor (MIF) or immunoglobulin G (IgG). Further described herein is a pharmaceutical composition which comprise these bi-functional compounds. Further described herein is a method for treating disease states and/or conditions with the compounds or the composition. The disease states and/or conditions are mediated through MIF/IgG or where MIF/IgG is a contributing factor to the development and perpetuation of diseases and/or conditions, such as autoimmune diseases and cancer, among others. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/161633 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/55 (20170801) Original (OR) Class A61K 47/545 (20170801) A61K 47/549 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050590 | Tsai et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yi-Ting Tsai (New York, New York); Stephen H. Tsang (New York, New York) |
| ABSTRACT | The present disclosure relates to methods for regulating cholesterol efflux in retinal pigment epithelium cells and treating or preventing a neurodegenerative disease or disorder (e.g., macular degeneration). |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/495538 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1808 (20130101) A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050593 | Poss et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Kenneth Poss (Durham, North Carolina); Valentina Cigliola (Durham, North Carolina); Adam Shoffner (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are compositions and methods of treating a spinal cord injury and improving spinal cord function. Also disclosed are compositions and methods of stimulating regeneration, promoting glial cell proliferation, promoting axonal tract regeneration, triggering neurite outgrowth, and triggering neuron formation in injured and/or damaged spinal cord tissue. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 18/267898 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050599 | Babich et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | John W. Babich (New York, New York); James M. Kelly (New York, New York); Alejandro Amor-Coarasa (New York, New York); Shashikanth Ponnala (New York, New York) |
| ABSTRACT | The present technology provides compounds, as well as compositions including such compounds, useful for imaging and/or treatment of a glioma, a breast cancer, an adrenal cortical cancer, a cervical carcinoma, a vulvar carcinoma, an endometrial carcinoma, a primary ovarian carcinoma, a metastatic ovarian carcinoma, a non-small cell lung cancer, a small cell lung cancer, a bladder cancer, a colon cancer, a primary, gastric adenocarcinoma, a primary colorectal adenocarcinoma, a renal cell carcinoma, and/or a prostate cancer. |
| FILED | Thursday, February 23, 2023 |
| APPL NO | 18/113206 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0402 (20130101) A61K 51/0482 (20130101) Original (OR) Class A61K 51/0497 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050621 | Dana et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Reza Dana (Newton, Massachusetts); Nasim Annabi (Los Angeles, California); Clotilde Jumelle (Somerville, Massachusetts); Ehsan Shirzaei Sani (Los Angeles, California) |
| ABSTRACT | The present disclosure presents sealant compositions which can be used in the treatment of an ocular surface injury and methods of treating an ocular surface injury in a subject in need thereof. The sealant compositions can include methacrylated hyaluronic acid (MeHA); GelMA; optionally, poly(ethylene glycol) diacrylate (PEGDA); and a visible light-activated photoinitiator. The methods include applying a sealant composition to an applicator; placing the applicator containing the sealant composition onto a surface of the eye of a subject, wherein the surface of the eye has or is suspected of having the ocular surface injury; and photo-crosslinking the sealant composition by exposing the applicator and the sealant composition to a visible light, for example, a visible light having a wavelength of about 400 nanometers (nm) to 800 nm. |
| FILED | Thursday, October 08, 2020 |
| APPL NO | 17/766445 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/08 (20130101) Original (OR) Class A61L 24/0031 (20130101) A61L 24/043 (20130101) A61L 2430/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050631 | HANDA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hitesh HANDA (ATHENS, Georgia); Ryan P. DEVINE (Athens, Georgia); Megan Elizabeth BROOKS (Athens, Georgia) |
| ABSTRACT | Described herein are substrates, devices, methods for treating and preventing bacterial and fungal infections, such as infections associated with medical devices, and the like. Materials, substrates and devices of the present disclosure include materials, such as medical grade polymers, having a coating/layer of polyene antimycotic molecules coupled to a surface of the polymer substrate. In certain aspects, substrates and devices of the present disclosure also include a nitric oxide (NO) releasing material also embedded in/coated on the material. Methods of the present disclosure includes methods of making the compositions and/or devices of the present disclosure including materials functionalized with polyene antimycotic molecules and NO releasing materials. Embodiments also include methods of using the materials, substrates, and devices of the present disclosure to treat/prevent fungal and/or bacterial infections in a subject, particularly infections associated with the use of a medical device. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 18/016095 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/16 (20130101) A61L 29/085 (20130101) Original (OR) Class A61L 29/126 (20130101) A61L 2300/114 (20130101) A61L 2300/216 (20130101) A61L 2300/404 (20130101) A61L 2420/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050637 | WU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); BREETHE, INC (Halethorpe, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhongjun WU (Marriottsville, Maryland); Bartley GRIFFITH (Gibson Island, Maryland); David N. WELLS (Silver Spring, Maryland) |
| ABSTRACT | An oxygen supply unit for use with a blood oxygenator comprises an oxygen concentrator and a carbon dioxide scrubber. In an on-line operational mode, oxygen-rich gas from the oxygen concentrator is predominantly supplied to the blood oxygenator with a reduced flow of recycled gas from the concentrator. In an off-line operational mode where the oxygen supply unit is being powered by battery only, a larger flow of recycled gas from the blood oxygenator is passed through the carbon dioxide scrubber and combined with a lesser amount of oxygen-rich gas from the oxygen concentrator. The oxygen supply unit may be used in combination with a blood pump and oxygenator to provide ambulatory blood oxygenation to patients with compromised lung function. |
| FILED | Tuesday, May 02, 2023 |
| APPL NO | 18/310846 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1698 (20130101) A61M 1/3666 (20130101) A61M 1/3667 (20140204) Original (OR) Class A61M 2202/0208 (20130101) A61M 2205/8206 (20130101) A61M 2209/08 (20130101) A61M 2209/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050652 | Damiano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward R. Damiano (Acton, Massachusetts); Kirk D. Ramey (Tallahassee, Florida); Firas H. El-Khatib (Allston, Massachusetts) |
| ABSTRACT | A multi-medicament infusion system (10) for preventing the mischanneling of medicaments may include an infusion pump (12), medicament reservoirs (16A,16B), a multi-channel lumen (18), and an infusion set (20). The medicament reservoirs may be sized and shaped differently such that the medicament reservoirs can only be inserted into the infusion pump in a unique configuration. The multi-channel lumen may include connectors that mate to corresponding connectors on the infusion pump and the infusion set only in a unique configuration. Because the various parts of the multi-infusion system may only be connected in the unique configuration, the expected medicaments may be administered appropriately and channeled to the correct infusion sites. |
| FILED | Wednesday, June 28, 2023 |
| APPL NO | 18/215420 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/162 (20130101) A61M 5/1413 (20130101) A61M 5/1452 (20130101) Original (OR) Class A61M 5/1723 (20130101) A61M 5/16831 (20130101) A61M 2039/1094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050735 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Siwei Zhao (Omaha, Nebraska); Fan Zhao (Shanghai, China PRC) |
| ABSTRACT | Systems and methods for treating and inhibiting wound infections employ a hydrogel ionic circuit (HIC)-based device for therapeutic iontophoresis and/or biofilm debridement. The HIC-based device includes: a first chamber containing a salt solution; a second chamber containing a therapeutic or buffer solution, the second chamber being configured to interface with a surface overlaying a target region; a hydrogel membrane separating the first chamber from the second chamber; and an electrode configured to apply an electrical current to the first chamber of the working device to induce an ion current in the salt solution, wherein the ion current acts on the second chamber to iontophoretically transport therapeutic molecules across the surface overlaying the target region and/or debride biofilm at the surface overlaying the target region. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/493925 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/35 (20130101) A61K 38/12 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0468 (20130101) Original (OR) Class A61N 1/0472 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050746 | Angeli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Claudia Angeli (Louisville, Kentucky); Charles Hubscher (Louisville, Kentucky); Gail F. Forrest (Cranbury, New Jersey); Enrico Rejc (Louisville, Kentucky); Susan J. Harkema (Louisville, Kentucky); Maxwell Boakye (Louisville, Kentucky); Yury Gerasimenko (Louisville, Kentucky) |
| ABSTRACT | The present invention relates to systems and methods for improvement of physiological function in an individual with a spinal cord injury via electrical stimulation of the spinal cord. A 3D model of the spinal cord is used to determine an initial position for an electrode array to deliver stimulation. Spinal cord electrical stimulation is configurable to target different physiological functions with surgical implantation of the neurostimulator at a singular location. Such systems and methods include (i) anatomical specificity to target the appropriate region of the spinal cord for stimulation, (ii) electrical specificity to provide the appropriate stimulation by delivery method, frequency, pulse duration, and other factors, and (iii) physiological specificity to evoke, suppress, increase, or decrease a specific physiological result. |
| FILED | Thursday, August 10, 2023 |
| APPL NO | 18/447661 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/388 (20210101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36062 (20170801) Original (OR) Class A61N 1/36139 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050895 | BROWN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brooke A. BROWN (Bloomington, Indiana); David E. CLEMMER (Bloomington, Indiana); Martin F. JARROLD (Bloomington, Indiana) |
| ABSTRACT | A method for purifying particles generates charged particles from a sample, measures at least at least one of masses, charge magnitudes and mobilities of the generated charged particles, and selectively passes to a particle collection target each of the measured charged particles having at least one of (a) a measured mass equal to a selected mass or within a selected range of particle masses, (b) a measured charge magnitude equal to a selected charge magnitude or within a selected range of charge magnitudes, (c) a mass-to-charge ratio equal to a selected mass-to-charge ratio or within a selected range of mass-to-charge ratios, and (d) a measured mobility equal to a selected mobility or within a selected range of mobilities. In some embodiments, the collected particles may be harvested and amplified. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/766388 |
| CURRENT CPC | Separation B01D 59/46 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 3/40 (20130101) H01J 49/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050908 | MITCHELL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael J. MITCHELL (Philadelphia, Pennsylvania); David Aaron ISSADORE (Philadelphia, Pennsylvania); Sagar Prasad YADAVALI (Dowingtown, Pennsylvania); Sarah J. SHEPHERD (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided are scalable, parallelized microfluidic chips that include arrays of microfluidic mixing channels for large-scale production of lipid nanoparticles, among other products. The disclosed chips can operate with a single set of inlets and outlet, and achieve production rates in excess of those achieved by existing methods. The disclosed devices provide large-scale production of formulations while still maintaining the physical properties and potency typical of existing methods of producing such formulations. Also provided are related methods of using the disclosed devices. |
| FILED | Monday, December 27, 2021 |
| APPL NO | 18/259439 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5089 (20130101) A61K 39/215 (20130101) A61K 48/0041 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/45 (20220101) B01F 23/4105 (20220101) B01F 23/4143 (20220101) B01F 25/43172 (20220101) B01F 25/431971 (20220101) B01F 33/3012 (20220101) Original (OR) Class B01F 2101/22 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050912 | Borden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. Borden (Boulder, Colorado); Gazendra Shakya (Westminster, Colorado); Xiaoyun Ding (Superior, Colorado) |
| ABSTRACT | The inventive technology is directed to droplet compositions having novel endoskeletal and/or exoskeletal shell architectures configured to produce enhanced vaporization characteristics. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/766387 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/08 (20130101) B01J 13/0021 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050945 | Lenhard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Allison Lenhard (Torrance, California); David L. Trumper (Plaistow, New Hampshire); Linda G Griffith (Cambridge, Massachusetts) |
| ABSTRACT | A flow control system that produces smooth flow for on-chip pneumatic micropumps has been developed. By establishing a flow control system that can achieve smooth flow, fluidic conditions of microphysiological systems can be controlled to accurately mimic biological conditions. Biological experiments can require flow profiles anywhere on the spectrum of smooth flow to highly pulsatile flow. A smooth flow profile can be modified with pumping delays to make the flow profile as pulsatile as desired. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/446947 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) Original (OR) Class B01L 2300/069 (20130101) B01L 2300/0654 (20130101) B01L 2300/0874 (20130101) B01L 2400/082 (20130101) B01L 2400/0487 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051855 | BALL |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OXYTEC LLC (Newton, Massachusetts) |
| ASSIGNEE(S) | OXYTEC LLC (Newton, Massachusetts) |
| INVENTOR(S) | Raymond G. BALL (Newton, Massachusetts) |
| ABSTRACT | Disclosed are methods, apparatuses and systems for the remediation of contaminated soils, groundwater, water, and/or waste using a combination of reagents. The disclosed methods may be used to treat various recalcitrant halogenated substances, such as perfluoroalkyls and polyfluoroalkyls. Particular combinations of reagents that may be used in the disclosed methods include but are not limited to: (1) persulfate, oxygen and ozone; (2) persulfate, salt, oxygen and ozone; (3) persulfate, phosphate, and/or oxygen; (4) persulfate, phosphate, oxygen and ozone; (5) persulfate, phosphate, salt and oxygen (6) persulfate, phosphate, salt, oxygen and ozone; (7) oxygen and salt; and (8) air and salt. The disclosed methods may enhance destruction of organic contaminants in the liquid phase and may also control the rate of aerosol or foam formation relative to the rate of chemical oxidation and/or reduction/transfer. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/467812 |
| CURRENT CPC | Reclamation of Contaminated Soil B09C 1/002 (20130101) B09C 1/06 (20130101) B09C 1/08 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/32 (20130101) C02F 1/70 (20130101) C02F 1/78 (20130101) C02F 1/722 (20130101) Original (OR) Class C02F 1/725 (20130101) C02F 1/727 (20130101) C02F 2101/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051897 | DORSHEIMER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julia DORSHEIMER (New York, New York); Tomislav ROVIS (New York, New York) |
| ABSTRACT | Methods for conversion of a broad range of amines to their 15N isotopic counterparts and the compounds produced thereby. |
| FILED | Wednesday, July 26, 2023 |
| APPL NO | 18/359651 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) Original (OR) Class C07B 59/002 (20130101) C07B 2200/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051931 | Wipf et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Peter Wipf (Pittsburgh, Pennsylvania); Donna M. Huryn (Allentown, Pennsylvania); Matthew G. LaPorte (Pittsburgh, Pennsylvania); Leila Terrab (Pittsburgh, Pennsylvania); Michael James Houghton (Niskayuna, New York); Andrea Topacio (Pittsburgh, Pennsylvania); Taber Sarah Maskrey (Pittsburgh, Pennsylvania); Tyler Kristufek (Pittsburgh, Pennsylvania); Uygar Sozer (Long Island, New York); Desirae Lynn Crocker (Jeannette, Pennsylvania); Sipak Joyasawal (Pittsburgh, Pennsylvania); Alyssa Thornton (Washington, District of Columbia); Shikha Singh Chauhan (State College, Pennsylvania); Mary Liang (Pittsburgh, Pennsylvania); Prema Iyer (Carnegie, Pennsylvania); Jagannath Panda (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present disclosure is directed to chromane compounds, chromane compounds demonstrating HDAC inhibition, and pharmaceutical compositions thereof. Additional embodiments include methods of using the chromane compounds. For example, the disclosure includes methods of inhibiting histone acetylation in a cell, comprising contacting the cell with a chromane compound of the disclosure. Additional embodiments include methods of treating a disease capable of treatment by inhibition of histone acetylation in a patient in need thereof, comprising administering a chromane compound of the disclosure. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 18/039941 |
| CURRENT CPC | Heterocyclic Compounds C07D 265/36 (20130101) C07D 311/66 (20130101) Original (OR) Class C07D 405/04 (20130101) C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051950 | Sevrioukova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (oakand, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Irina F. Sevrioukova (Irvine, California); Eric R. Samuels (Long Beach, California) |
| ABSTRACT | The present invention provides novel compounds and compositions thereof inhibiting cytochrome P450 3A4 (CYP3A4). The present invention further provides a novel method of inhibiting CYP3A4 in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of the invention. In one embodiment, the subject is further administered at least one additional therapeutic agent. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 18/258610 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 213/82 (20130101) C07D 401/14 (20130101) C07D 405/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051959 | CHEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yu CHEN (Tampa, Florida); Michael SACCO (Tampa, Florida); James LEAHY (Tampa, Florida); Elena BRAY (Tampa, Florida); Xingmin SUN (Tampa, Florida); Xiujun ZHANG (Tampa, Florida) |
| ABSTRACT | Disclosed herein are compounds that can prevent and treat C. difficile by inhibiting sporulation. Also disclosed herein are compositions and formulations comprising the compound disclosed herein. Methods of preventing and treating C. difficile comprising administering the compounds described herein are also disclosed. |
| FILED | Wednesday, October 04, 2023 |
| APPL NO | 18/376525 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 471/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051992 | TAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Weiyi TAN (Waltham, Massachusetts); Bing XU (Newton, Massachusetts) |
| ABSTRACT | Disclosed are peptides having the structure according to formula (Ia) or (Ib) or (II): wherein NH-Q-C(O) is a peptide chain optionally comprising an amino acid residue having a sidechain covalently bonded to Z2; Z1 is a moiety comprising an aromatic group, a therapeutic agent, a fluorophore, or a nanoparticle; Z2 is H, a therapeutic agent, a fluorophore, or a nanoparticle; and J, if present (as in Ib or II), is a linker between the peptide chain and the thiophosphate group or thioester group. Also disclosed are pharmaceutical compositions that contain a peptide, as well as dephosphorylated peptides of the invention, which may take one or more forms include a nanofiber or a supramolecular hydrogel. Use of the peptides for delivering a therapeutic agent or drug moiety into the Golgi apparatus, imaging a cell, treating a patient having a cancerous condition, treating a patient having Alzheimer's or Parkinson's disease are also disclosed. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 18/546159 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 5/0812 (20130101) C07K 5/1016 (20130101) C07K 5/06121 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051995 | SEYEDSAYAMDOST et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOS, a body Corporate and politic of the states (Urbana, Illinois) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Mohammad R. SEYEDSAYAMDOST (Princeton, New Jersey); Michael J. FEDERLE (La Grange, Illinois); Brett C. COVINGTON (New Brunswick, New Jersey); Leah B. BUSHIN (San Diego, California); Britta E. RUED (Chicago, Illinois); John AMBROSE (Princeton, New Jersey) |
| ABSTRACT | There is currently a high demand for new therapeutic antibiotics with new mechanisms of action. Disclosed are two small molecules, tryglysin A and B, with novel chemical structures and potent antibiotic activity against a narrow spectrum of bacteria. This narrow spectrum of activity indicates the tryglysins could be working through a novel antibiotic mechanism of action. Due to this narrow spectrum, the tryglysins could be used as highly targeted therapeutics to treat or prevent disease without disturbing other important, “beneficial” bacteria within the human microbiome, which is a great improvement over virtually all other clinically used antibiotics that are broad-spectrum. The tryglysins are potent against several streptococcal pathogens, including Streptococcus pneumonia, the leading cause of pneumonia, and Streptococcus mutans, the primary causative agent of tooth decay and gum disease. The tryglycins may allow the development of therapeutics for the treatment and/or prevention of disease caused by these streptococci. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 18/266325 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 1/16 (20130101) C07K 7/06 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) C12N 2500/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052004 | BORDEY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Angelique BORDEY (Guilford, Connecticut); Lena NGUYEN (New Haven, Connecticut); Lawrence HSIEH (Hartford, Connecticut); Tiffany LIN (New Haven, Connecticut) |
| ABSTRACT | In various aspects and embodiments the invention provides a method of preventing seizures in a subject in need thereof, the method comprising contacting a target cell of the subject with a 4EBP-activating agent or a EIF4E-depleting agent. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/766455 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) Peptides C07K 14/4702 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/86 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052028 | Bassik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael C. Bassik (Stanford, California); Roarke Kamber (Stanford, California) |
| ABSTRACT | The present disclosure provides methods for treating a disease or disorder or sensitizing a cell to phagocytosis. The methods comprise contacting a cell with an inhibitor of Adipocyte Plasma Membrane Associated Protein (APMAP), an agonist of fatty-acid G-protein coupled receptor GPR84, or a combination thereof. The methods may further comprise contacting the cell with at least one or both of a tumor antigen (TA)-targeting antibody and a CD47 blocking antibody. The present disclosure also provides methods for determining cellular regulators of phagocytosis. |
| FILED | Tuesday, October 05, 2021 |
| APPL NO | 18/030223 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/70596 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/2896 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052079 | Pfeifer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carmem Pfeifer (Beaverton, Oregon); Wilbes Mbiya (Portland, Oregon); Ana Paula Piovezan Fugolin (Portland, Oregon); Jack Ferracane (Beaverton, Oregon); Justin Merritt (Portland, Oregon); Matthew Logan (Portland, Oregon) |
| ABSTRACT | Provided herein are novel compounds of Formula (I): wherein R1 is selected from the group of C1-C20 alkyl, —CH2—CH2—CH2—NH—C(=O)—C=C, and —CH2—CH2—CH2—N(CH3)—C (=O)—C=C; along with compositions comprising them and uses, including as dental adhesive compositions. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 18/269150 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/30 (20200101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/50 (20130101) C08F 222/385 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052097 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chien-Chi Lin (Bloomington, Indiana); Fang-Yi Lin (Bloomington, Indiana) |
| ABSTRACT | Methods for synthesizing a hydrogel having tunable hydrolylic degradation kinetics according to certain embodiments include synthesizing a norborene-functionalized polyethylene glycol macromer having an ester linkage between a polyethylene glycol domain of the macromer and a norbornene domain of the macromer and having a carboxyl group on the norbornene; and reacting a quantity of such macromers with a quantity of dithiol molecules by an ultraviolet-initiated photo-gelation reaction to yield a hydrogel. Such macromers and such hydrogels form additional aspects of the disclosure, as do a wide variety of methods for tuning and for using such hydrogels. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 18/264508 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/34 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 27/3834 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/334 (20130101) C08G 65/3324 (20130101) Original (OR) Class C08G 65/3331 (20130101) C08G 2210/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2371/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0662 (20130101) C12N 2533/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052325 | BEESE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lorena S. BEESE (Durham, North Carolina); You WANG (Durham, North Carolina); Yuqian SHI (Durham, North Carolina) |
| ABSTRACT | The present invention relates to fusion proteins and methods of using the same. Specifically, invention relates to fusion proteins comprising an intein and a DNA polymerase, and methods of using the same for DNA synthesis. |
| FILED | Tuesday, January 26, 2021 |
| APPL NO | 18/021270 |
| CURRENT CPC | Peptides C07K 2319/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1252 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Enzymes C12Y 207/07007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052331 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Board Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Travis R. Blum (Cambridge, Massachusetts); Min Dong (Boston, Massachusetts); Hao Liu (Boston, Massachusetts) |
| ABSTRACT | The disclosure provides fusion proteins comprising a pleckstrin homology (PH) domain and a variant of Botulinum neurotoxin E (BoNT E) protease that cleaves certain non-canonical protein targets (e.g., PTEN). Fusion proteins described in the disclosure are useful for cleaving target proteins found in a cell, that is, in an intracellular environment. Aspects of the disclosure provide methods for inhibiting PTEN amount, activity, or function in a cell or subject, the methods comprising administering to a call or subject a fusion protein described herein. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 18/268178 |
| CURRENT CPC | Peptides C07K 14/4703 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/52 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2740/15043 (20130101) Enzymes C12Y 301/04011 (20130101) C12Y 304/24069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052338 | Diao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Yarui Diao (Durham, North Carolina); Xiaolin Wei (Durham, North Carolina); Yu Xiang (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are compositions for and methods of performing a multi-omics assay comprising analyzing chromatin structure and function and analyzing the transcriptome using the same population of cells. Disclosed herein are compositions for and methods of performing a high-throughput chromosome conformation capture on accessible DNA and mRNA-Seq co-assay (HiCAR). |
| FILED | Tuesday, November 02, 2021 |
| APPL NO | 18/033002 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 45/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052352 | Chilton |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Floyd H. Chilton (Tucson, Arizona) |
| ABSTRACT | Provided herein are biomarkers for screening and monitoring of conditions, diseases, and disorders. In particular, provided herein are sPLA2 biomarkers for use in characterizing, prognosing, and treating disorders associated with elevated sPLA2. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 18/278196 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/20 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) Enzymes C12Y 301/01004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052368 | Majumder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kinjal Majumder (Madison, Wisconsin); Clairine Larsen (Madison, Wisconsin) |
| ABSTRACT | The present invention provides constructs for producing modified recombinant adeno-associated virus (rAAV) vectors. The constructs comprise one or more CCCTC-binding factor (CTCF) binding sites, which facilitate DNA looping and promote efficient transgene expression. Also provided are modified rAAV virus particles comprising these constructs, methods for producing the modified rAAV virus particles, and methods of using the modified rAAV virus particles to deliver a transgene to a subject. |
| FILED | Friday, June 09, 2023 |
| APPL NO | 18/332380 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14143 (20130101) C12N 2750/14152 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052399 | Bowler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ABBOTT DIAGNOSTICS SCARBOROUGH, INC. (Scarborough, Maine) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Frank Ray Bowler (Norfolk, United Kingdom); Grzegorz Artur Orlowski (Cambridgeshire, United Kingdom); Hazel Lucy Greetham (Cambridgeshire, United Kingdom); Cheng Zhou (Cambridgeshire, United Kingdom); Niall A. Armes (Suffolk, United Kingdom); Olaf Piepenburg (Essex, United Kingdom) |
| ABSTRACT | This invention relates to sequence specific electrochemically-labeled oligonucleotide probes for the detection of nucleic acids and methods associated therewith. |
| FILED | Monday, May 15, 2023 |
| APPL NO | 18/317200 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6876 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052400 | Green et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Green (Scottsdale, Arizona); Duo Ma (Tempe, Arizona); Anli Tang (Gilbert, Arizona) |
| ABSTRACT | Methods and compositions for detecting the presence of a pathogen are described. In particular, this document provides a method of detecting a pathogen-associated nucleic acid in a biological sample of a subject, where the method comprises using one or more unimolecular aptamer-based sensors comprising an aptamer-fluorophore complex and an amplification step to detect the pathogen-associated nucleic acid. Methods specific for detecting the presence of malaria and other mosquito-borne virus infections are also provided. |
| FILED | Monday, August 21, 2023 |
| APPL NO | 18/453129 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6825 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052402 | Xiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ming Xiao (Huntingdon Valley, Pennsylvania); Jennifer McCaffrey (Collegeville, Pennsylvania) |
| ABSTRACT | A method of detecting the length of an individual telomere is provided. In one embodiment, the method includes contacting genomic DNA with a guide RNA having a portion complementary to a telomere repeat sequence in the genomic DNA and with Cas9 nickase to produce a single-strand break in the genomic DNA at the telomere repeat sequence. The nicked DNA is contacted with a polymerase and fluorescently labeled nucleotide, wherein the fluorescently labeled nucleotide is incorporated into the nicked DNA at the telomere repeat sequence. The genomic DNA is contacted with a second nicking endonuclease which is specific for a sequence motif in the genomic DNA thereby producing a second nick in the genomic DNA at the motif sequence. The nicked DNA is contacted with a polymerase and second fluorescently labeled nucleotide of different color, wherein the second fluorescently labeled nucleotide is incorporated into the nicked DNA at the motif sequence location. The length of the telomere is detected by measuring the fluorescence of first fluorescently labeled nucleotide at the telomere repeat location, wherein the fluorescently labeled motif sequences are used as a barcode to identify the chromosome. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/467927 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) Original (OR) Class C12Q 2521/101 (20130101) C12Q 2521/307 (20130101) C12Q 2563/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052421 | IAVARONE et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Antonio IAVARONE (Sunny Isles Beach, Florida); Anna LASORELLA (New York, New York) |
| ABSTRACT | The subject matter disclosed herein relates to a method of treating glioblastoma (GBM) in a subject in need thereof, the method comprising determining one or more GBM subtypes in a GBM sample via a pathway-based classifier approach and administering to the subject a pharmaceutically effective amount of an agent capable of modifying the activity of the biological pathways associated with the one or more GMB subtypes. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 18/259067 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052428 | SHIPP et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Margaret SHIPP (Boston, Massachusetts); Gad GETZ (Boston, Massachusetts); Bjoern CHAPUY (Boston, Massachusetts); Kirsty WIENAND (Boston, Massachusetts); Donald STEWART (Cambridge, Massachusetts); Andrew DUNFORD (Cambridge, Massachusetts); Mark MURAKAMI (Boston, Massachusetts); Lee LAWTON (Boston, Massachusetts) |
| ABSTRACT | The invention provides compositions and methods useful in characterizing and/or treating classical Hodgkin's Lymphoma and/or primary mediastinal B-cell lymphoma (PMBL). In embodiments, the characterization is carried out using a biological sample comprising circulating tumor DNA (ctDNA) from a subject. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/468298 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053264 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ji-Xin Cheng (Newton, Massachusetts); Lu Lan (Allston, Massachusetts); Jiaze Yin (Malden, Massachusetts) |
| ABSTRACT | A mid-infrared photothermal microscopy system images a sample. A mid-infrared optical source generates a mid-infrared beam which is directed along a first optical path to reach the substrate on a first side and heat the sample. A probe light source generates a probe light which is directed along a second optical path to reach the substrate on a second side and illuminate the sample. A first laser scanner is positioned along the first optical path and configured to rotate to redirect light and scan the sample with the mid-infrared beam. A second laser scanner is positioned along the second optical path and configured to rotate to redirect light and scan the sample with the probe light. The laser scanners each include at least one mirror driven to rotate such that the mid-infrared beam and the probe light scan the sample synchronously. |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/234195 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 21/359 (20130101) Original (OR) Class G01N 21/6458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053291 | XIAO et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yi XIAO (Cary, North Carolina); Yingzhu LIU (Wuhan, China PRC); Juan CANOURA (Hialeah Gardens, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Yi XIAO (Cary, North Carolina); Yingzhu LIU (Wuhan, China PRC); Juan CANOURA (Hialeah Gardens, Florida) |
| ABSTRACT | The subject invention provides methods for fabricating electrochemical aptamer-based (E-AB) sensors with enhanced sensitivity, signal-to-noise ratios, LOD, and improved stability and reproducibility. The subject invention also provides methods for aptamer immobilization on the surface of the electrode, which favors sufficient spacing between aptamers at the microscale to achieve optimal target recognition, folding, and signal transduction. The E-AB sensors of the subject invention provide superior sensing regardless of the sequence or structure of the bound aptamers or the physiochemical properties of the target. |
| FILED | Monday, October 23, 2023 |
| APPL NO | 18/492169 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3276 (20130101) Original (OR) Class G01N 27/3277 (20130101) G01N 33/5308 (20130101) G01N 33/5438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053295 | Burch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kenneth S. Burch (Brighton, Massachusetts); Tim van Opijnen (Somerville, Massachusetts); Jianmin Gao (Newton, Massachusetts); Narendra Kumar (Brighton, Massachusetts); Juan C. Ortiz-Marquez (Brighton, Massachusetts); Wenjian Wang (Brighton, Massachusetts); Mason Gray (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Kenneth S. Burch (Brighton, Massachusetts); Tim van Opijnen (Somerville, Massachusetts); Jianmin Gao (Newton, Massachusetts); Narendra Kumar (Brighton, Massachusetts); Juan C. Ortiz-Marquez (Brighton, Massachusetts); Wenjian Wang (Brighton, Massachusetts); Mason Gray (Chestnut Hill, Massachusetts) |
| ABSTRACT | A method and system for label-free detection of pathogenic and antibiotic resistant bacteria is disclosed. The method includes fabricating a G-FET/peptide device having a synthesized peptide probe capable of recognizing and binding to a bacterial target; performing electric-field assisted binding of at least one bacterial cell of the bacterial target to the G-FET/peptide device; and electrically detecting the binding of the at least one bacterial cell to the G-FET/peptide device. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/486542 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) Original (OR) Class G01N 27/4146 (20130101) G01N 27/4148 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053326 | El-Deiry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wafik S. El-Deiry (Barrington, Rhode Island); Kelsey E. Huntington (Providence, Rhode Island); Anna Louie (Providence, Rhode Island) |
| ABSTRACT | A method of treating a subject having colon cancer with a small molecule drug for treating colon cancer is described. The method includes determining the effect of the small molecule drug on the release of a plurality of immunomodulating factors by colon cancer cells; and treating the subject with a therapeutically effect amount of the drug if the effect of the drug on the release of immunomodulating factors indicates that the drug promotes anti-tumor immunity, or selecting a different drug for treating colon cancer if the effect of the drug on immunomodulating factor release indicates that the drug does not promote anti-tumor immunity. Methods of evaluating ongoing treatment using the method are also described. |
| FILED | Monday, August 07, 2023 |
| APPL NO | 18/230872 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5041 (20130101) Original (OR) Class G01N 2333/475 (20130101) G01N 2333/521 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053342 | Weiss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan Weiss (Athens, Georgia); Thomas Mandel Clausen (San Diego, California); Jeffrey D. Esko (San Diego, California) |
| ABSTRACT | Methods of detecting and treating an epithelial carcinoma, such as pancreatic ductal adenocarcinoma cancer or bladder cancer, expressing antithrombin-binding heparan sulfate (HSAT) in a subject, comprising combining a biological sample of the subject containing HSAT with antithrombin and detecting binding of HSAT and the antithrombin, optionally determining that the antithrombin inhibits factor Xa. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 18/257838 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/4833 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) Original (OR) Class G01N 2333/8128 (20130101) G01N 2474/20 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053358 | CASTELLANA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ABTERRA BIOSCIENCES, INC. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Natalie CASTELLANA (San Diego, California); Stefano BONISSONE (San Diego, California); Anand PATEL (San Diego, California) |
| ABSTRACT | Embodiments of the present disclosure relate to protein identification methods, including identification of amino acid sequences in a heterogeneous mixture of immunoglobulin and immunoglobulin-like protein molecules for reconstruction of variable regions and/or CDR3 region segments of one or more immunoglobulins. |
| FILED | Thursday, October 05, 2023 |
| APPL NO | 18/481945 |
| CURRENT CPC | Peptides C07K 1/1075 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/20 (20190201) G16B 40/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053364 | Glezer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
| ASSIGNEE(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
| INVENTOR(S) | Eli N. Glezer (Del Mar, California); John Kenten (Boyds, Maryland); Sudeep Kumar (Basking Ridge, New Jersey); Galina Nikolenko (Germantown, Maryland) |
| ABSTRACT | The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein. |
| FILED | Monday, March 27, 2023 |
| APPL NO | 18/126546 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2333/4706 (20130101) G01N 2333/4727 (20130101) G01N 2333/8146 (20130101) G01N 2333/70578 (20130101) G01N 2333/70596 (20130101) G01N 2800/52 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053369 | Vaisar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington); The University of Western Ontario (London, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tomas Vaisar (Seattle, Washington); Santica M. Marcovina (Seattle, Washington); Marlys Laverne Koschinsky (London, Canada); Michael Busiku Boffa (London, Canada) |
| ABSTRACT | The present disclosure provides methods, systems, and kits for quantifying lipoprotein(a) based on measuring selected proteotypic peptide(s). The methods of the disclosure are also useful in determining if a subject is at risk to develop cardiovascular disease. The disclosure also provides methods of determining a reference amount of selected proteotypic peptide(s) in a reference sample. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/257719 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 33/6851 (20130101) G01N 33/6893 (20130101) G01N 2800/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055101 | Panetta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts); Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts); Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Karen A. Panetta (Rockport, Massachusetts); Shishir Paramathma Rao (Burlington, Massachusetts); Shreyas Kamath Kalasa Mohandas (Burlington, Massachusetts); Rahul Rajendran (Belleville, Michigan); Srijith Rajeev (Burlington, Massachusetts); Erin Hennessy (North Reading, Massachusetts); Christina Economos (Concord, Massachusetts); Eleanor Tate Shonkoff (Reading, Massachusetts); Sos S. Agaian (New York, New York) |
| ABSTRACT | The disclosure generally relates to the artificial intelligence (AI) automatic methods, computer program product, and systems and methodology for dietary and medical treatment planning, food waste estimation, analyzing three-dimensional food image construction, measurement, nutrient estimation, nutritional assessment, evaluation, prediction and management. More particularly, the embodiments described herein relate to utilizing an AI-based algorithm that can automatically, detect food items from images acquired by cameras for dietary assessment, dietary planning, and for estimating food waste. In one aspect, the method may include food calorie estimation techniques using machine learning and computer vision techniques for dietary assessment. In another aspect, the tools may apply to personalized nutrition. The method may also include the automation of nutrition planning. In yet another aspect, the tools may apply to medical treatment planning, wherein meals and treatment plans are individualized explicitly for each user according to several unique characteristics associated with that user. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 18/256971 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0464 (20230101) G06N 20/10 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/60 (20180101) Original (OR) Class G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055126 | Wujek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Thaddeus Wujek (Milwaukee, Wisconsin); Kathleen Marie Schmainda (Elm Grove, Wisconsin) |
| ABSTRACT | Systems and methods are described for segmenting medical images, such as magnetic resonance images, using a deep learning model that has been trained using random dropped inputs, standardized inputs, or both. Medical images can be segmented based on anatomy, physiology, pathology, other properties or characteristics represented in the medical images, or combinations thereof. As one example, multi-contrast magnetic resonance images are input to the trained deep learning model in order to generate multiple segmented medical images, each representing a different segmentation class. |
| FILED | Friday, October 20, 2023 |
| APPL NO | 18/491282 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/143 (20170101) G06T 2207/10088 (20130101) G06T 2207/20084 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055596 | MENG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiangbo MENG (Fayetteville, Arkansas); Xin WANG (Fayetteville, Arkansas) |
| ABSTRACT | Nickel-rich layered oxide electrodes are described herein having high conductivity coatings which, in some embodiments, mitigate degradative pathways, maintain electrode performance and enhance electrode lifetimes. In one aspect, an electrode comprises nickel-rich layered oxide, and a sulfide-based coating or oxide-based coating over the nickel-rich layered oxide, the sulfide-based or oxide-based coating having an ionic conductivity greater than 1×10−4 S/cm at room temperature. In some embodiments, the ionic conductivity is at least 1×10−3 S/cm at room temperature. Moreover, the sulfide-based coating can comprise a ternary sulfide, the ternary sulfide comprising lithium and aluminum. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 18/267829 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0428 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 4/5815 (20130101) H01M 10/052 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20240049717 | ISLAM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAFIQUL ISLAM (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | RAFIQUL ISLAM (GILBERT, Arizona); Dianne Carrillo (Gilbert, Arizona); Yuqiang Bi (GILBERT, Arizona); ALI ANSARI (GILBERT, Arizona) |
| ABSTRACT | The present invention provides among other things silver nanoparticles and methods of making the same. The nanoparticles may be sulfidated to decrease the silver leaching rate and sustain the biocidal properties. Such nanoparticles may be applied as a coating or additive to substrates such as metals, alloys, polymers, membranes, textiles, and other such materials, allowing for the substrates to exhibit antimicrobial properties. |
| FILED | Thursday, October 05, 2023 |
| APPL NO | 18/376985 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/26 (20130101) A01N 59/16 (20130101) Original (OR) Class Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 1/00 (20210801) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/16 (20220101) B22F 1/056 (20220101) B22F 1/142 (20220101) B22F 9/24 (20130101) B22F 2301/255 (20130101) B22F 2302/45 (20130101) B22F 2304/054 (20130101) B22F 2304/058 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050219 | Genin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri); Columbia University (New York, New York) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); Columbia University (New York, New York) |
| INVENTOR(S) | Guy Genin (St. Louis, Missouri); Ethan Hoppe (St. Louis, Missouri); Dong Hwan Yoon (St. Louis, Missouri); Stavros Thomopoulos (New York, New York); Iden Kurtaliaj (NY, New York); Liana Tedesco (NY, New York); David Kovacevic (NY, New York); Victor Birman (St. Louis, Missouri); Lester Smith (Indianapolis, Indiana); Leesa Galatz (St. Louis, Missouri); William Levine (New York, New York) |
| ABSTRACT | Devices and methods for joining a first and second tissue in a patient are disclosed that include a base with a plurality of recurved tines oriented to a tine axis and extending from a first surface of the base. The tines provide unidirectional traction of the first tissue along the tine axis toward the first surface. The first tissue is secured to the first surface of the device at the plurality of recurved tines and the second tissue is secured to the device at a second surface opposite the first surface to join the first and second tissues. |
| FILED | Monday, October 05, 2020 |
| APPL NO | 17/766503 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0077 (20130101) A61F 2/0811 (20130101) Original (OR) Class A61F 2002/0829 (20130101) A61F 2002/0858 (20130101) A61F 2002/0888 (20130101) A61F 2210/0004 (20130101) A61F 2220/0016 (20130101) A61F 2230/0019 (20130101) A61F 2250/0028 (20130101) A61F 2250/0058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050627 | Lippmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ethan S. Lippmann (Nashville, Tennessee); Brian O'Grady (Nashville, Tennessee); David C. Florian (Nashville, Tennessee); Scott A. Guelcher (Nashville, Tennessee) |
| ABSTRACT | Provided are biomaterials and methods useful for promoting large blood vessel growth in a subject. An example biomaterial includes a crosslinked hydrogel and a peptide chemically attached to the hydrogel wherein the peptide comprises an extracellular epitope of a cadherin protein. An example method includes administering to an area of the subject a therapeutically effective amount of the biomaterial, wherein the biomaterial provides artery growth, arteriole growth, a combination thereof in the area of administration. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 18/268009 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/222 (20130101) A61L 27/507 (20130101) Original (OR) Class A61L 2300/25 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050931 | Gao |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pu-Xian Gao (Coventry, Connecticut) |
| ABSTRACT | Solid porous composite ZSM-5 materials comprising a generally vertical orientation of an array of pentacil-zeolite crystals on a porous substrate. |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/234099 |
| CURRENT CPC | Separation B01D 53/864 (20130101) B01D 2255/504 (20130101) B01D 2255/9202 (20130101) B01D 2255/9205 (20130101) B01D 2255/9207 (20130101) B01D 2255/20746 (20130101) B01D 2257/702 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/75 (20130101) B01J 29/46 (20130101) Original (OR) Class B01J 35/04 (20130101) B01J 35/006 (20130101) B01J 35/1014 (20130101) B01J 35/1019 (20130101) B01J 35/1038 (20130101) B01J 37/0217 (20130101) B01J 37/0219 (20130101) B01J 37/0228 (20130101) B01J 37/0244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051218 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); IBM Almaden Research Center (San Jose, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); IBM Almaden Research Center (San Jose, California) |
| INVENTOR(S) | Jiali Zhang (Davis, California); Victoria A. Puinova (San Jose, California); Yang Liu (Davis, California); Jane Frommer (San Jose, California); Gang-Yu Liu (Davis, California) |
| ABSTRACT | The disclosed embodiments provide a system that performs molecular assembly. During operation, the system delivers one or more droplets of a fluid onto a surface using a nanofluidic delivery probe and an associated high-precision positioning device, wherein the solution comprises a solvent and one or more solute molecules, and wherein delivery of the droplets onto the surface facilitates evaporation-driven assembly of one or more structures on the surface. Moreover, while delivering a droplet onto the surface, the system controls a size of the droplet and a shape of the droplet during evaporation to produce a variety of shapes in resulting structures. |
| FILED | Tuesday, October 06, 2020 |
| APPL NO | 17/766495 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Original (OR) Class B29C 64/209 (20170801) B29C 64/393 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/0073 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 70/00 (20141201) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0004 (20130101) B82B 3/0014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051891 | HOLDEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FULL CIRCLE MICROBES, INC. (Hinesburg, Vermont) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victoria I. HOLDEN (Hinesburg, Vermont); Charles SMITH (Hinesburg, Vermont); Katelynn KOSKIE (Hinesburg, Vermont) |
| ABSTRACT | Disclosed are microbial compositions having unique combinations of microbial species which are used in plant material recycling to form a nutrient source. Also disclosed microbial inoculants which contains such a microbial composition, water, and an optional carbon source. The microbial compositions and microbial inoculants are particularly useful in recycling high lignin-content plant material. Methods of making and methods of using the microbial compositions and the microbial inoculants are also described. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 18/259683 |
| CURRENT CPC | Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 17/20 (20200101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051897 | DORSHEIMER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julia DORSHEIMER (New York, New York); Tomislav ROVIS (New York, New York) |
| ABSTRACT | Methods for conversion of a broad range of amines to their 15N isotopic counterparts and the compounds produced thereby. |
| FILED | Wednesday, July 26, 2023 |
| APPL NO | 18/359651 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) Original (OR) Class C07B 59/002 (20130101) C07B 2200/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051992 | TAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Weiyi TAN (Waltham, Massachusetts); Bing XU (Newton, Massachusetts) |
| ABSTRACT | Disclosed are peptides having the structure according to formula (Ia) or (Ib) or (II): wherein NH-Q-C(O) is a peptide chain optionally comprising an amino acid residue having a sidechain covalently bonded to Z2; Z1 is a moiety comprising an aromatic group, a therapeutic agent, a fluorophore, or a nanoparticle; Z2 is H, a therapeutic agent, a fluorophore, or a nanoparticle; and J, if present (as in Ib or II), is a linker between the peptide chain and the thiophosphate group or thioester group. Also disclosed are pharmaceutical compositions that contain a peptide, as well as dephosphorylated peptides of the invention, which may take one or more forms include a nanofiber or a supramolecular hydrogel. Use of the peptides for delivering a therapeutic agent or drug moiety into the Golgi apparatus, imaging a cell, treating a patient having a cancerous condition, treating a patient having Alzheimer's or Parkinson's disease are also disclosed. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 18/546159 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 5/0812 (20130101) C07K 5/1016 (20130101) C07K 5/06121 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051995 | SEYEDSAYAMDOST et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOS, a body Corporate and politic of the states (Urbana, Illinois) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Mohammad R. SEYEDSAYAMDOST (Princeton, New Jersey); Michael J. FEDERLE (La Grange, Illinois); Brett C. COVINGTON (New Brunswick, New Jersey); Leah B. BUSHIN (San Diego, California); Britta E. RUED (Chicago, Illinois); John AMBROSE (Princeton, New Jersey) |
| ABSTRACT | There is currently a high demand for new therapeutic antibiotics with new mechanisms of action. Disclosed are two small molecules, tryglysin A and B, with novel chemical structures and potent antibiotic activity against a narrow spectrum of bacteria. This narrow spectrum of activity indicates the tryglysins could be working through a novel antibiotic mechanism of action. Due to this narrow spectrum, the tryglysins could be used as highly targeted therapeutics to treat or prevent disease without disturbing other important, “beneficial” bacteria within the human microbiome, which is a great improvement over virtually all other clinically used antibiotics that are broad-spectrum. The tryglysins are potent against several streptococcal pathogens, including Streptococcus pneumonia, the leading cause of pneumonia, and Streptococcus mutans, the primary causative agent of tooth decay and gum disease. The tryglycins may allow the development of therapeutics for the treatment and/or prevention of disease caused by these streptococci. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 18/266325 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 1/16 (20130101) C07K 7/06 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) C12N 2500/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052097 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chien-Chi Lin (Bloomington, Indiana); Fang-Yi Lin (Bloomington, Indiana) |
| ABSTRACT | Methods for synthesizing a hydrogel having tunable hydrolylic degradation kinetics according to certain embodiments include synthesizing a norborene-functionalized polyethylene glycol macromer having an ester linkage between a polyethylene glycol domain of the macromer and a norbornene domain of the macromer and having a carboxyl group on the norbornene; and reacting a quantity of such macromers with a quantity of dithiol molecules by an ultraviolet-initiated photo-gelation reaction to yield a hydrogel. Such macromers and such hydrogels form additional aspects of the disclosure, as do a wide variety of methods for tuning and for using such hydrogels. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 18/264508 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/34 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 27/3834 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/334 (20130101) C08G 65/3324 (20130101) Original (OR) Class C08G 65/3331 (20130101) C08G 2210/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2371/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0662 (20130101) C12N 2533/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052134 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Lidia Kuo (Evanston, Illinois); Benjamin J. Luijten (Evanston, Illinois); Ana Carolina Mazarin de Moraes (Westmont, Illinois); Shay G. Wallace (Beavercreek, Ohio) |
| ABSTRACT | The invention relates to a sterilizable and reusable ultraviolet-resistant elastomer composites including an elastomeric matrix comprising at least one elastomer; and an UV-resistant additive incorporated into the elastomeric matrix. The ultraviolet-resistant elastomer composite remains mechanically robust over at least 150 sterilization cycles, enabling safe reuse following ultraviolet germicidal irradiation (UVGI). Beyond N95 masks, these UVGI-compatible ultraviolet-resistant elastomer composites have potential utility in other PPE applications to address the broader issue of single-use waste. |
| FILED | Wednesday, August 02, 2023 |
| APPL NO | 18/229231 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/12 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/203 (20130101) C08J 2375/00 (20130101) C08J 2401/28 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/042 (20170501) Original (OR) Class C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 2201/08 (20130101) C08L 2312/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052374 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Garret P. Miller (Waltham, Massachusetts); Björn Hamberger (Okemos, Michigan); Imani Pascoe (East Lansing, Michigan); Kathryn Van Winkle (Medford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Garret P. Miller (Waltham, Massachusetts); Björn Hamberger (Okemos, Michigan); Imani Pascoe (East Lansing, Michigan); Kathryn Van Winkle (Medford, Massachusetts) |
| ABSTRACT | Enzymes and methods are described herein for manufacturing terpenes, including diterpenoid alkaloids. |
| FILED | Monday, July 24, 2023 |
| APPL NO | 18/357767 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/04 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/007 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052492 | Chan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Candace Chan (Phoenix, Arizona); Jon Mark Weller (Phoenix, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Candace Chan (Phoenix, Arizona); Jon Mark Weller (Phoenix, Arizona) |
| ABSTRACT | Forming a lithium lanthanum zirconate thin film includes disposing zirconium oxide on a substrate to yield a zirconium oxide coating, contacting the zirconium oxide coating with a solution including a lithium salt and a lanthanum salt, heating the substrate to yield a dried salt coating on the zirconium oxide coating, melting the dried salt coating to yield a molten salt mixture, reacting the molten salt mixture with the zirconium oxide coating to yield lithium lanthanum zirconate, and cooling the lithium lanthanum zirconate to yield a lithium lanthanum zirconate coating on the substrate. In some cases, the zirconium oxide coating is contacted with an aqueous molten salt mixture including a lithium salt and a lanthanum salt, the molten salt mixture is reacted with the zirconium oxide coating to yield lithium lanthanum zirconate, and the lithium lanthanum zirconate is cooled to yield a lithium lanthanum zirconate coating on the substrate. |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/493561 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/405 (20130101) C23C 16/45555 (20130101) C23C 18/1216 (20130101) C23C 18/1295 (20130101) C23C 22/05 (20130101) C23C 22/70 (20130101) Original (OR) Class C23C 28/042 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 2300/0077 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052572 | Zheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yi Zheng (Boston, Massachusetts); Yanpei Tian (Boston, Massachusetts); Xiaojie Liu (Boston, Massachusetts) |
| ABSTRACT | Disclosed are composite paper materials comprising hydrophobic fluorocarbons. Also disclosed are passive cooling materials comprising the composite paper materials. Further disclosed are methods of making the composite paper materials. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 18/269192 |
| CURRENT CPC | Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for D21H 17/11 (20130101) Original (OR) Class D21H 21/28 (20130101) D21H 27/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053266 | Srinivasan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kannan Srinivasan (Columbus, Ohio); Wei Sun (Columbus, Ohio) |
| ABSTRACT | An example system for remote sensing of a road surface includes an antenna configured to transmit and receive radiofrequency (RF) signals, where the antenna is configured to attach to a front end of a vehicle; at least one radiofrequency identification (RFID) tag, where the at least one RFID tag is configured to attach to the front end of a vehicle; and an RFID reader, wherein the RFID reader is configured to: cause the antenna to transmit a radiofrequency signal toward a road surface, where the at least one RFID tag receives a backscattered RF signal from the road surface; receive, from the antenna, an RFID signal from the first RFID tag, the RFID signal comprising phase and magnitude information; and analyze the phase and magnitude information to determine a condition of the road surface. |
| FILED | Monday, June 12, 2023 |
| APPL NO | 18/208494 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) Original (OR) Class G01N 23/04 (20130101) G01N 2021/4709 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053291 | XIAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yi XIAO (Cary, North Carolina); Yingzhu LIU (Wuhan, China PRC); Juan CANOURA (Hialeah Gardens, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Yi XIAO (Cary, North Carolina); Yingzhu LIU (Wuhan, China PRC); Juan CANOURA (Hialeah Gardens, Florida) |
| ABSTRACT | The subject invention provides methods for fabricating electrochemical aptamer-based (E-AB) sensors with enhanced sensitivity, signal-to-noise ratios, LOD, and improved stability and reproducibility. The subject invention also provides methods for aptamer immobilization on the surface of the electrode, which favors sufficient spacing between aptamers at the microscale to achieve optimal target recognition, folding, and signal transduction. The E-AB sensors of the subject invention provide superior sensing regardless of the sequence or structure of the bound aptamers or the physiochemical properties of the target. |
| FILED | Monday, October 23, 2023 |
| APPL NO | 18/492169 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3276 (20130101) Original (OR) Class G01N 27/3277 (20130101) G01N 33/5308 (20130101) G01N 33/5438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053295 | Burch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kenneth S. Burch (Brighton, Massachusetts); Tim van Opijnen (Somerville, Massachusetts); Jianmin Gao (Newton, Massachusetts); Narendra Kumar (Brighton, Massachusetts); Juan C. Ortiz-Marquez (Brighton, Massachusetts); Wenjian Wang (Brighton, Massachusetts); Mason Gray (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Kenneth S. Burch (Brighton, Massachusetts); Tim van Opijnen (Somerville, Massachusetts); Jianmin Gao (Newton, Massachusetts); Narendra Kumar (Brighton, Massachusetts); Juan C. Ortiz-Marquez (Brighton, Massachusetts); Wenjian Wang (Brighton, Massachusetts); Mason Gray (Chestnut Hill, Massachusetts) |
| ABSTRACT | A method and system for label-free detection of pathogenic and antibiotic resistant bacteria is disclosed. The method includes fabricating a G-FET/peptide device having a synthesized peptide probe capable of recognizing and binding to a bacterial target; performing electric-field assisted binding of at least one bacterial cell of the bacterial target to the G-FET/peptide device; and electrically detecting the binding of the at least one bacterial cell to the G-FET/peptide device. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/486542 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) Original (OR) Class G01N 27/4146 (20130101) G01N 27/4148 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053330 | Carothers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | James M. Carothers (Seattle, Washington); Jesse Zalatan (Seattle, Washington); David Sparkman-Yager (Seattle, Washington); Jason Fontana (Seattle, Washington) |
| ABSTRACT | Disclosed are kinetically-controlled RNA biosensor constructs and related, nucleic acids, vectors, cells, systems and methods useful for detecting ligands of interest. Also disclosed are computer implemented methods for designing kinetically-controlled biosensors, guide RNA molecules, and/or target promoter sequences, and constructs produced thereby. Exemplary embodiments include scRNAs and expression cassettes incorporating synthetic promoters for implementation of CRISPRa. |
| FILED | Tuesday, January 04, 2022 |
| APPL NO | 18/260305 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/94 (20130101) G01N 33/542 (20130101) G01N 33/5308 (20130101) Original (OR) Class G01N 2333/922 (20130101) G01N 2333/9005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053541 | ZHANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yang ZHANG (Hyattsville, Maryland); Mario DAGENAIS (Chevy Chase, Maryland); Sylvain VEILLEUX (Chevy Chase, Maryland); Jiahao ZHAN (College Park, Maryland); Pradip GATKINE (Pasadena, California); Wei-Lun HSU (Silver Spring, Maryland) |
| ABSTRACT | An arrayed waveguide grating (AWG) can have a reusable delay line, a plurality of coupling devices, and a free propagation region (FPR). The delay line can have a continuous first waveguide connected to receive a plurality of wavelengths. Each coupling device can have a second waveguide coupled to a respective portion of the continuous first waveguide. The FPR can have input and output ends. The input end of the FPR can be coupled to receive the radiation from each of the coupling devices. The radiation can be directed to spatially-separated output channels based on wavelength at the output end of the FPR. The plurality of coupling devices and the delay line are configured to control power and phase distributions of the radiation transmitted to the FPR. |
| FILED | Tuesday, May 16, 2023 |
| APPL NO | 18/197857 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/2861 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053619 | Porras Aguilar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rosario Guadalupe Porras Aguilar (Concord, North Carolina) |
| ABSTRACT | A quantitative phase contrast imaging system comprises a light source configured to generate light and to direct the light to a sample, wherein the light comprises nonlinearly polarized light; a first lens configured to receive light from the sample; a phase filter, wherein the first lens is configured to focus the light from the sample onto the phase filter, and the phase filter is configured to modulate multiple components of the nonlinearly polarized light simultaneously (e.g., geometric phase interferometry); a second lens configured to receive light from the phase filter; and a polarized camera, wherein the second lens is configured to collimate the light beam from the phase filter to the polarized camera and the polarized camera is configured to image the sample in response to the light from the phase filter. In absence of the second lens, the camera can be placed at the image plane. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/446517 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/3016 (20130101) G02B 21/14 (20130101) G02B 21/36 (20130101) G02B 27/288 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053653 | XU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jimmy XU (Providence, Rhode Island); Petr MOROSHKIN (Providence, Rhode Island); Akshay NAGAR (Providence, Rhode Island) |
| ABSTRACT | A photon source for generating entangled photons includes a pump laser, and 4-N, N-dimethylamino-4′-N′-methyl-stilbazolium-tosylate (DAST) crystals, the pump laser pumping the DAST crystals with pump photons to generate a stream of pairs of entangled photons, each pair comprising a signal photon and an idler photon. |
| FILED | Thursday, February 16, 2023 |
| APPL NO | 18/170068 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3503 (20210101) G02F 1/3551 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240054331 | Srinivasa |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Narayan Srinivasa (San Jose, California) |
| ABSTRACT | A spiking neuromorphic network may be used to solve an optimization problem. The network may include primary neurons. The state of a primary neuron may be a value of a corresponding variable of the optimization problem. The primary neurons may update their states and change values of the variables. The network may also include a cost neuron that can compute, using a cost function, costs based on values of the variables sent to the cost neuron in the form of spikes from the primary neurons. The network may also include a minima neuron for determining the lowest cost and an integrator neuron for tracking how many computational steps the primary neurons have performed. The minima neuron or integrator neuron may determine whether convergence is achieved. After the convergence is achieved, the minima neuron or integrator neuron may instruct the primary neurons to stop computing new values of the variables. |
| FILED | Wednesday, October 18, 2023 |
| APPL NO | 18/489327 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240054399 | HONG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| INVENTOR(S) | TAE MIN HONG (PITTSBURGH, Pennsylvania); BENJAMIN T. CARLSON (SANTA BARBARA, California); JOERG H. STELZER (CHEMNITZ, Germany); STEPHEN T. ROCHE (NAPERVILLE, Illinois); STEPHEN T. RACZ (NORTH HUNTINGDON, Pennsylvania); DANIEL C. STUMPP (NEW CUMBERLAND, Pennsylvania); QUINCY BAYER (MURRYSVILLE, Pennsylvania); BRANDON R. EUBANKS (PITTSBURGH, Pennsylvania) |
| ABSTRACT | A system for providing a boosted decision tree (BDT) for use on an electronic device to provide an event score based on a user input event, where the device includes: a machine learning trainer configured to create a trained BDT from an untrained BDT by determining parameters for the untrained BDT; a nanosecond optimizer configured to create an optimized BDT, the nanosecond optimizer including at least one of a tree flattener, a tree merger, a score normalizer, a tree remover, and a cut eraser; and a converter coupled to the nanosecond optimizer and configured to receive the optimized BDT from the nanosecond optimizer and convert the optimized BDT to a language for high-level-synthesis to produce a hardware description language representation of the optimized BDT, wherein the hardware description language representation of the optimized BDT is structured and configured to be implemented in firmware provided on the electronic device. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 18/264877 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240054841 | Skrabalak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | The Trustees of Indiana University (Bloomington, Indiana) |
| INVENTOR(S) | Sara E. Skrabalak (Bloomington, Indiana); Alison F. Smith (Bloomington, Indiana); Joshua D. Smith (Avon, Indiana) |
| ABSTRACT | A method of using at least one nanoparticle for an anti-counterfeit application including selecting the at least one nanoparticle having a non-spherical configuration; providing the at least one nanoparticle on a substrate; providing a light to the at least one nanoparticle; determining a position of the at least one nanoparticle based on providing the light to the at least one nanoparticle; determining a color of the at least one nanoparticle based on providing the light to the at least one nanoparticle; defining a nanofingerprint based on the position and the color of the at least one nanoparticle; and recognizing the nanofingerprint. |
| FILED | Thursday, October 08, 2020 |
| APPL NO | 17/766480 |
| CURRENT CPC | Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 3/144 (20130101) Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/205 (20130101) G07D 7/1205 (20170501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055020 | Singer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenneth Singer (Cleveland, Ohio); Irina Shiyanovskaya (Solon, Ohio) |
| ABSTRACT | An optical information storage medium includes a substrate and a multilayer polymeric film. The multilayer polymeric film has a first surface and an opposite second surface that extend the length of the multilayer polymeric film. The second surface is adhered to a surface of the substrate. The multilayer polymeric film includes a plurality of coextruded alternating polymeric active data storage layers and polymeric buffer layers. |
| FILED | Monday, October 23, 2023 |
| APPL NO | 18/382780 |
| CURRENT CPC | Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 7/26 (20130101) G11B 7/0052 (20130101) G11B 7/0079 (20130101) G11B 7/242 (20130101) G11B 7/24027 (20130101) G11B 7/24038 (20130101) Original (OR) Class G11B 7/24056 (20130101) G11B 7/24065 (20130101) G11B 2007/0013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055122 | SHADE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Julie K. SHADE (Baltimore, Maryland); Ashish DOSHI (Baltimore, Maryland); Eric SUNG (Baltimore, Maryland); Allison HAYS (Baltimore, Maryland); Natalia A. TRAYANOVA (Baltimore, Maryland) |
| ABSTRACT | Provided herein are methods of generating models for prognosing cardiovascular outcomes for monitored subjects infected with an etiologic agent (e.g., severe acute respiratory syndrome coronavirus-2 or another etiologic agent). Related methods, systems, and computer program products are also provided. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 18/257925 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7267 (20130101) A61B 5/7275 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055154 | Marion et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Juliette Marion (Paris, France); Polina Olegovna ANIKEEVA (Lexington, Massachusetts); Yoel FINK (Brookline, Massachusetts) |
| ABSTRACT | An elastic and conductive fiber includes a cladding with a channel and a conductor disposed therein. The cladding may be made of a thermoplastic elastomer. The conductive fiber includes an excess length of conductor disposed inside of the channel so that the conductive fiber can stretch without applying substantial strain to the conductor and without substantially changing the electrical resistance of the conductive fiber. The conductor inside of the channel may have a buckled shape or a helical shape. |
| FILED | Friday, June 09, 2023 |
| APPL NO | 18/332326 |
| CURRENT CPC | Woven Fabrics; Methods of Weaving; Looms D03D 1/0088 (20130101) D03D 15/25 (20210101) D03D 15/30 (20210101) D03D 15/283 (20210101) D03D 15/292 (20210101) Knitting D04B 1/16 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2321/02 (20130101) D10B 2401/061 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 3/44 (20130101) H01B 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055596 | MENG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiangbo MENG (Fayetteville, Arkansas); Xin WANG (Fayetteville, Arkansas) |
| ABSTRACT | Nickel-rich layered oxide electrodes are described herein having high conductivity coatings which, in some embodiments, mitigate degradative pathways, maintain electrode performance and enhance electrode lifetimes. In one aspect, an electrode comprises nickel-rich layered oxide, and a sulfide-based coating or oxide-based coating over the nickel-rich layered oxide, the sulfide-based or oxide-based coating having an ionic conductivity greater than 1×10−4 S/cm at room temperature. In some embodiments, the ionic conductivity is at least 1×10−3 S/cm at room temperature. Moreover, the sulfide-based coating can comprise a ternary sulfide, the ternary sulfide comprising lithium and aluminum. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 18/267829 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0428 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 4/5815 (20130101) H01M 10/052 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240056711 | COVEY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob Paul COVEY (Savoy, Illinois); William Chiu Wong HUIE (Urbana, Illinois); Jia Pern Neville CHEN (Champaign, Illinois); Lintao LI (Urbana, Illinois); Hannes BERNIEN (Chicago, Illinois); Shankar GIRIJAVALLABHAN MENON (Chicago, Illinois) |
| ABSTRACT | The disclosure includes a multiplexed telecommunication-band quantum network that utilizes atomic arrays in optical cavities. An example quantum networking system includes at least one quantum repeater node. The quantum repeater node includes an array of neutral atoms disposed in an optical cavity and a fiber-optic switch (FOS). The FOS is optically coupled to the optical cavity. The quantum repeater node also includes at least one beamsplitter. The at least one beamsplitter is optically coupled to the FOS. |
| FILED | Friday, July 07, 2023 |
| APPL NO | 18/219512 |
| CURRENT CPC | Transmission H04B 10/70 (20130101) Selecting H04Q 11/0067 (20130101) Original (OR) Class H04Q 2213/13191 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240050107 | Donaldson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Critical Innovations LLC (Lawndale, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ross I. Donaldson (Lawndale, California); Oliver Buchanan (Lawndale, California); Muhammed Hamdan (Lawndale, California); Tim Fisher (Lawndale, California); John Cambridge (Lawndale, California); Jonathan Armstrong (Lawndale, California) |
| ABSTRACT | An improved method and device are provided for forming and/or maintaining a percutaneous access pathway. The device generally comprises an access pathway. The provided assembly substantially reduces the possibility of injury while accessing and/or re-accessing a body space. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/496616 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00234 (20130101) A61B 17/1615 (20130101) A61B 17/1695 (20130101) Original (OR) Class A61B 17/3423 (20130101) A61B 2017/00238 (20130101) A61B 2017/3425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050127 | Donaldson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Critical Innovations LLC (Lawndale, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ross I. Donaldson (Los Angeles, California); Oliver Buchanan (Los Angeles, California); Muhammed Hamden (Los Angeles, California); Zhirair Yesayan (Los Angeles, California); Timothy Fisher (Los Angeles, California) |
| ABSTRACT | An improved method and device are provided for forming and/or maintaining a percutaneous access pathway. The device generally comprises an access pathway. The provided assembly substantially reduces the possibility of injury while accessing and/or re-accessing a body space. |
| FILED | Friday, August 11, 2023 |
| APPL NO | 18/448455 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3417 (20130101) A61B 17/3474 (20130101) Original (OR) Class A61B 17/3494 (20130101) A61B 17/3498 (20130101) A61B 2017/0023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050413 | Rammohan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Miami (Miami, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kottil W. Rammohan (Miami, Florida) |
| ABSTRACT | Disclosed herein are compositions and methods for treating multiple sclerosis and alleviating fatigue. |
| FILED | Friday, September 24, 2021 |
| APPL NO | 18/028338 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) A61K 31/4172 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050578 | Spiegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); David Caianiello (New Haven, Connecticut) |
| ABSTRACT | Described herein is a bi-functional compound for removing macrophage migration inhibitory factor (MIF) or immunoglobulin G (IgG). Further described herein is a pharmaceutical composition which comprise these bi-functional compounds. Further described herein is a method for treating disease states and/or conditions with the compounds or the composition. The disease states and/or conditions are mediated through MIF/IgG or where MIF/IgG is a contributing factor to the development and perpetuation of diseases and/or conditions, such as autoimmune diseases and cancer, among others. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/161633 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/55 (20170801) Original (OR) Class A61K 47/545 (20170801) A61K 47/549 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050621 | Dana et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Reza Dana (Newton, Massachusetts); Nasim Annabi (Los Angeles, California); Clotilde Jumelle (Somerville, Massachusetts); Ehsan Shirzaei Sani (Los Angeles, California) |
| ABSTRACT | The present disclosure presents sealant compositions which can be used in the treatment of an ocular surface injury and methods of treating an ocular surface injury in a subject in need thereof. The sealant compositions can include methacrylated hyaluronic acid (MeHA); GelMA; optionally, poly(ethylene glycol) diacrylate (PEGDA); and a visible light-activated photoinitiator. The methods include applying a sealant composition to an applicator; placing the applicator containing the sealant composition onto a surface of the eye of a subject, wherein the surface of the eye has or is suspected of having the ocular surface injury; and photo-crosslinking the sealant composition by exposing the applicator and the sealant composition to a visible light, for example, a visible light having a wavelength of about 400 nanometers (nm) to 800 nm. |
| FILED | Thursday, October 08, 2020 |
| APPL NO | 17/766445 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/08 (20130101) Original (OR) Class A61L 24/0031 (20130101) A61L 24/043 (20130101) A61L 2430/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050626 | Beachley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rowan University (Glassboro, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vince Beachley (Medford Lakes, New Jersey); Sebastian L. Vega (Sewell, New Jersey); Dave Joa (Glassboro, New Jersey) |
| ABSTRACT | The present disclosure relates to a multi-layer composite comprising at least a first sheet and a second sheet of aligned nanofibers coated with a biodegradable hydrogel, wherein the at least first and second sheets of aligned coated nanofibers are stacked directly on top of each other and a portion of the biodegradable hydrogel coating on the first sheet is mixed and crosslinked with a portion of the biodegradable hydrogel coating on the second sheet. In another aspect, the present disclosure relates to a method of regenerating an aligned soft tissue in a subject, the method comprising surgically implanting a synthetic tissue graft comprising the multi-layer composite in the subject at a site of missing or injured tissue. In yet another aspect, the present disclosure relates to a synthetic nerve graft comprising the multi-layer composite. |
| FILED | Friday, May 27, 2022 |
| APPL NO | 18/251166 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) Original (OR) Class A61L 27/52 (20130101) A61L 27/58 (20130101) A61L 2400/12 (20130101) A61L 2430/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051150 | Khripin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alex Khripin (Waltham, Massachusetts); Stephen Berard (Waltham, Massachusetts); Alfred Rizzi (Cambridge, Massachusetts) |
| ABSTRACT | An example robot includes a hydraulic actuator cylinder controlling motion of a member of the robot. The hydraulic actuator cylinder comprises a piston, a first chamber, and a second chamber. A valve system controls hydraulic fluid flow between a hydraulic supply line of pressurized hydraulic fluid, the first and second chambers, and a return line. A controller may provide a first signal to the valve system so as to begin moving the piston based on a trajectory comprising moving in a forward direction, stopping, and moving in a reverse direction. The controller may provide a second signal to the valve system so as to cause the piston to override the trajectory as it moves in the forward direction and stop at a given position, and then provide a third signal to the valve system so as to resume moving the piston in the reverse direction based on the trajectory. |
| FILED | Thursday, September 14, 2023 |
| APPL NO | 18/467127 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 5/00 (20130101) B25J 9/20 (20130101) Original (OR) Class Motor Vehicles; Trailers B62D 57/032 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 9/09 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051230 | Bonanno et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Bonanno (Fairfax Station, Virginia); Blerta Markowski (Springfield, Virginia); Brian Hicks (Alexandria, Virginia); Freddie Santiago (Fort Washington, Maryland) |
| ABSTRACT | Systems and methods are provided for achieving more accurate 3D printed parts than printed parts achieved by conventional means. The disclosed systems and methods reduce the need for tolerance fitting when designing 3D objects and manufacturing with stereolithographic 3D printers. Embodiments of the present disclosure enable fitted assemblies to be manufactured and produce accurate standoffs where size constraints are critical. Embodiments of the present disclosure realize these solutions without requiring modifications to the printer or the printer software. |
| FILED | Friday, August 12, 2022 |
| APPL NO | 17/887413 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/268 (20170801) B29C 64/393 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051684 | Warner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raymond Warner (Atlanta, Georgia); Michael Jeffries (Atlanta, Georgia); Christopher Keel (Atlanta, Georgia); Joshua Hurt (Atlanta, Georgia) |
| ABSTRACT | An exemplary embodiment of the present disclosure provides a device for securing a load, the device comprising a sled, a snubber, and a wedge. The sled can be configured to be coupled to the load. The snubber can be coupled to the sled and configured to be inserted into a chamber. The snubber can comprise a slot. The snubber can be configured to move between a contracted position and one or more expanded positions. The wedge can be configured to be inserted into the slot in a distal direction to cause the snubber to transition from the contracted position to the one or more expanded positions. The snubber can form an interference fit with an internal wall of the chamber when in a first expanded position of the one or more expanded positions to fix the location of the load relative to the chamber. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/231944 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/641 (20130101) Original (OR) Class Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 2/10 (20130101) F16B 2/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052096 | Dennis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army DEVCOM, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph M. Dennis (Chicago, Illinois); Joseph L. Lenhart (Port Deposit, Maryland); Randy A. Mrozek (Port Deposit, Maryland); Timothy W. Sirk (Churchville, Maryland); Juan De Pablo (Chicago, Illinois) |
| ABSTRACT | In various aspects, a cured polymer glass may be provided. The cured polymer glass may include a polymer glass component (such as an epoxide component and an amine component), and an azobenzene photo-responsive modifying agent. The modifying agent may cause a reversible transition in the cured polymer glass from a first state to a second state when the modifying agent is exposed to a light condition (such as specific wavelengths of light). The glass transition temperature (Tg) of the cured polymer glass may be at least 100° C. The first state may have at least one different mechanical property than the second state. The reversible transition may be configured to occur when the cured polymer glass is at a first temperature below a Tg of the cured polymer glass. |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/228356 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/24 (20130101) C08G 65/2603 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/23 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/02 (20130101) C09K 2211/1007 (20130101) C09K 2211/1014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052227 | Alms et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Justin B. Alms (Coventry, Connecticut); John A. Sharon (West Hartford, Connecticut); Stephen P. Zeppieri (Glastonbury, Connecticut) |
| ABSTRACT | A method includes obtaining thermal energy from a structure to be cooled, where the structure includes micro-channels. The method also includes providing the thermal energy to a water-based polymer network, where the water-based polymer network includes a gel formed using a polymer and water. The method further includes generating one or more gases by heating the water-based polymer network, where generating the one or more gases includes releasing the water in the water-based polymer network to produce steam. In addition, the method includes passing the one or more gases through the micro-channels to remove at least some of the thermal energy from the structure. |
| FILED | Friday, August 12, 2022 |
| APPL NO | 17/819513 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/40 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 20/06 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052307 | Matsuoka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); Cell Guidance Systems Limited (Cambridge, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Akihiro J. Matsuoka (Chicago, Illinois); Kevin Tomy Nella (Glenview, Illinois); Michael Jones (Cambridge, United Kingdom) |
| ABSTRACT | In one aspect, this invention relates to a bioactive implant comprising an electrode array; and a source of neurotrophins coupled with the electrode array for generating a neurotrophin concentration gradient that facilitates a neuro-regenerative nexus (NRN) for survival, neuronal differentiation toward spiral ganglion neurons (SGNs), and directed neurite extension of human pluripotent stem cell (hPSC)-derived SGNs. The invention in another aspect also relates to a method for realization of the NRN in conjunction with an implant, comprising coupling a source of neurotrophins with the electrode array to generate a neurotrophin concentration gradient that facilitates the NRN for survival, neuronal differentiation toward SGNs, and directed neurite extension of hPSC-derived SGNs. |
| FILED | Wednesday, August 02, 2023 |
| APPL NO | 18/229273 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) Original (OR) Class C12N 5/0607 (20130101) C12N 13/00 (20130101) C12N 2501/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052493 | McLeod et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aaron McLeod (La Jolla, California); Scott Ueda (Whittier, California); Andrew Kummel (San Diego, California) |
| ABSTRACT | This invention allows for the deposition of aluminum nitride buffer layers and templating films that greatly enhance the quality of additional aluminum nitride deposited by alternate deposit ion techniques and reduce the overall thickness of needed buffer layers. Furthermore, these films can be deposited at substrate temperatures of 400° C. and 580° C. which is considerably lower than other techniques, such as molecular beam epitaxy (MBE) and metal organic chemical vapor deposition (MOCVD). |
| FILED | Tuesday, May 02, 2023 |
| APPL NO | 18/311011 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 28/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052555 | HOLLAND |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory HOLLAND (San Diego, California) |
| ABSTRACT | In alternative embodiments, provided are biomaterials comprising hydrated, or hydrated and dried, orb-weaving spider aciniform (AC) prey-wrapping silks, or orb-weaving spider aciniform (AC) prey-wrapping silks that have been substantially converted into β-sheet aggregates or β-sheet nanocrystallite structures, which can be fabricated into products of manufacture, or films, fibers or threads, including fibers or threads woven into textiles or cloths. In alternative embodiments, provided are hydrated, or hydrated and dried, orb-weaving spider aciniform (AC) prey-wrapping silks, or orb-weaving spider aciniform (AC) prey-wrapping silks, substantially comprising β-sheet aggregates or B-sheet nanocrystallite structures, and products of manufacture, or fibers or threads, comprising these β-sheet aggregate-comprising silks or β-sheet nanocrystallite structures. In alternative embodiments, provided are methods for making hydrated, or hydrated and dried, orb-weaving spider aciniform (AC) prey-wrapping silks, or orb-weaving spider aciniform (AC) prey-wrapping silks, substantially comprising β-sheet aggregates or β-sheet nanocrystallite structures. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 18/267721 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/40 (20130101) A61L 31/005 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/05 (20130101) Original (OR) Class D06M 2101/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053303 | BEHANDISH |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Morad BEHANDISH (San Mateo, California) |
| ABSTRACT | A nondestructive method for detecting damage in parts and/or characterizing effective material properties may include: exposing a material to one or more nondestructive stimuli; measuring a response of the material to the stimuli; selecting at least one of a specific length scale or a specific time scale; and analyzing the measurement of the response with a scale-aware single- or multi-physics model to identify anomalies in the measurements as compared to an expected response of the material to the stimuli, wherein the scale-aware single- or multi-physics model is based on the at least one of the specific length scale or the specific time scale. |
| FILED | Friday, August 12, 2022 |
| APPL NO | 17/819515 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/041 (20130101) G01N 29/4472 (20130101) Original (OR) Class G01N 29/4481 (20130101) G01N 2291/02818 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053653 | XU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jimmy XU (Providence, Rhode Island); Petr MOROSHKIN (Providence, Rhode Island); Akshay NAGAR (Providence, Rhode Island) |
| ABSTRACT | A photon source for generating entangled photons includes a pump laser, and 4-N, N-dimethylamino-4′-N′-methyl-stilbazolium-tosylate (DAST) crystals, the pump laser pumping the DAST crystals with pump photons to generate a stream of pairs of entangled photons, each pair comprising a signal photon and an idler photon. |
| FILED | Thursday, February 16, 2023 |
| APPL NO | 18/170068 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3503 (20210101) G02F 1/3551 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240054100 | Brewer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony Brewer (Plano, Texas) |
| ABSTRACT | Disclosed in some examples, are methods, systems, programmable atomic units, and machine-readable mediums that provide an exception as a response to the calling processor. That is, the programmable atomic unit will send a response to the calling processor. The calling processor will recognize that the exception has been raised and will handle the exception. Because the calling processor knows which process triggered the exception, the calling processor (e.g., the Operating System) can take appropriate action, such as terminating the calling process. The calling processor may be a same processor as that executing the programmable atomic transaction, or a different processor (e.g., on a different chiplet). |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/383311 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4406 (20130101) G06F 15/82 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240054294 | SIKKA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karan SIKKA (Robbinsville, New Jersey); Meng YE (Lawrenceville, New Jersey); Ajay DIVAKARAN (Monmouth Junction, New Jersey) |
| ABSTRACT | A method, apparatus and system for moderating multilingual content data, for example, presented during a communication session include receiving or pulling content data that can include multilingual content, classifying, using a first machine learning system, the content data by projecting the content data into a trained embedding space to determine at least one English-language classification for the content data, and determining, using a second machine learning system, if the content data violates at least one predetermined moderation rule, wherein the second machine learning system is trained to determine from English-language classifications determined by the first machine learning system if the content data violates moderation rules. In some embodiments, the method apparatus and system can further include prohibiting a presentation of the content data related to the at least one English-language classification determined to violate the at least one predetermined moderation rule. |
| FILED | Monday, August 14, 2023 |
| APPL NO | 18/233658 |
| CURRENT CPC | Electric Digital Data Processing G06F 40/35 (20200101) G06F 40/40 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240054502 | SCHROEDER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael A. SCHROEDER (Chandler, Arizona); Sean BUSHELL (Peoria, Arizona); William F. HERRINGTON (Scottsdale, Arizona); Hannah ROWE (Chandler, Arizona); Sarah SHAHRAINI (Newcastle, Washington); Ryan PATE (Gilbert, Arizona); Erasenthiran POONJOLAI (Chandler, Arizona); Saikumar JAYARAMAN (Chandler, Arizona); Fariaz KARIM (GILBERT, Arizona) |
| ABSTRACT | The present disclosure is directed to an authentication system, tools, and methods for authentication including a first inspection tool that generates first images for a first inspection of a device, and a first processor for processing the first images using a hashing algorithm, for which the first inspection tool and the first processor are sited at a first location, and a second inspection tool that generates second images for a second inspection of the device, and a second processor for processing the second images using the hashing algorithm, for which the second inspection tool and the second processor are sited at a second location. The second processor compares the first and second sets of hash values to authenticate the device as being authentic and untampered. |
| FILED | Tuesday, August 09, 2022 |
| APPL NO | 17/883718 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/018 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/14 (20220101) G06V 20/80 (20220101) G06V 20/95 (20220101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055154 | Marion et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Juliette Marion (Paris, France); Polina Olegovna ANIKEEVA (Lexington, Massachusetts); Yoel FINK (Brookline, Massachusetts) |
| ABSTRACT | An elastic and conductive fiber includes a cladding with a channel and a conductor disposed therein. The cladding may be made of a thermoplastic elastomer. The conductive fiber includes an excess length of conductor disposed inside of the channel so that the conductive fiber can stretch without applying substantial strain to the conductor and without substantially changing the electrical resistance of the conductive fiber. The conductor inside of the channel may have a buckled shape or a helical shape. |
| FILED | Friday, June 09, 2023 |
| APPL NO | 18/332326 |
| CURRENT CPC | Woven Fabrics; Methods of Weaving; Looms D03D 1/0088 (20130101) D03D 15/25 (20210101) D03D 15/30 (20210101) D03D 15/283 (20210101) D03D 15/292 (20210101) Knitting D04B 1/16 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2321/02 (20130101) D10B 2401/061 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 3/44 (20130101) H01B 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055545 | Hill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David John Hill (Lawrenceville, New Jersey); Winston K. Chan (Princeton, New Jersey) |
| ABSTRACT | An example image intensifier includes a quantum well infrared photodetector (QWIP) configured to receive photons to photoexcite carriers out of a localized quantum state; and a light emitting diode (LED), wherein the photoexcited carriers control the LED. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/446996 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/153 (20130101) Original (OR) Class H01L 31/1113 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 45/10 (20200101) H05B 47/11 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055603 | CRONIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California); The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges (Stillwater, Oklahoma) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California); The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges (Stillwater, Oklahoma) |
| INVENTOR(S) | Stephen B. CRONIN (Los Angeles, California); Sisi YANG (Los Angeles, California); Özgür ÇAPRAZ (Stillwater, Oklahoma); Bertan OZDOGRU (Stillwater, Oklahoma) |
| ABSTRACT | This invention relates to alkali metal (Li, Na, K) ion batteries, electrodes for alkali metal ion batteries, and methods for manufacturing electrodes for alkali metal ion batteries. |
| FILED | Tuesday, October 05, 2021 |
| APPL NO | 18/267194 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0404 (20130101) H01M 4/583 (20130101) Original (OR) Class H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055640 | Suzuki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Toshio Suzuki (New Haven, Connecticut); Timothy LaBreche (Woodbridge, Connecticut); Christian Junaedi (Cheshire, Connecticut); Subir Roychoudhury (Madison, Connecticut) |
| ABSTRACT | This invention pertains to a reinforced porous metal substrate that finds utility in a backbone-structured metal-supported electrochemical cell and to methods of fabricating the reinforced porous metal substrate. In another aspect, this invention pertains to a backbone-structured metal-supported electrochemical cell repeat unit constructed by weld sealing or diffusion bonding the reinforced porous metal substrate to a metal frame. In another aspect, this invention pertains to an electrochemical cell and stack. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/547203 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/14 (20130101) B22F 3/1007 (20130101) B22F 7/004 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/0058 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/19 (20210101) C25B 13/07 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0258 (20130101) H01M 8/0273 (20130101) H01M 8/1226 (20130101) Original (OR) Class H01M 8/1286 (20130101) H01M 8/2425 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055648 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Navitas Systems, LLC (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pu Zhang (Ann Arbor, Michigan); Michael Wixom (Ann Arbor, Michigan); Qingliu Wu (Ann Arbor, Michigan) |
| ABSTRACT | Provided are electrode active materials with a porous structure and including a metal, that when loaded with sulfur serve as electrochemically superior cathode active materials. The metal structures are optionally used on their own, are coated with another material, or coats another porous structure such as a porous carbon structure that allows for excellent retention of both sulfur and polysulfides, are conductive themselves, and show long term stability and excellent cycle life. |
| FILED | Friday, October 20, 2023 |
| APPL NO | 18/382150 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/0402 (20130101) H01M 4/624 (20130101) H01M 4/625 (20130101) H01M 4/663 (20130101) H01M 4/808 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) Original (OR) Class H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240056285 | Tousi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yahya Tousi (Minnetonka, Minnesota); Ruixing He (Minneapolis, Minnesota) |
| ABSTRACT | A mm-wave signal generation technique that provides background phase tuning and self-alignment between adjacent sources. This technique is based on direct monitoring of the mm-wave signal and provides phase tuning through a baseband feedback loop. The techniques may be advantageous for phase alignment of large-scale mm-wave phased arrays. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/446986 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 7/033 (20130101) H04L 7/0079 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240056317 | Gauthier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andrew Joseph Pomerance (Alexandria, Virginia); Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Gauthier (Hilliard, Ohio); Andrew Joseph Pomerance (Alexandria, Virginia) |
| ABSTRACT | Described herein are methods and systems implementing physically unclonable functions (PUFs). An example method includes: inputting a first challenge bit string into a first PUF; capturing a first response bit string from the first PUF; inputting a second challenge bit string into a second PUF; capturing a second response bit string from the second PUF; performing a hash operation on the first response bit string and the second response bit string, the hash operation generating a hashed-response bit string; and storing the first and second challenge bit strings and the hashed-response bit string in a first database. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/123595 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0656 (20130101) H04L 9/3236 (20130101) H04L 9/3278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240050931 | Gao |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pu-Xian Gao (Coventry, Connecticut) |
| ABSTRACT | Solid porous composite ZSM-5 materials comprising a generally vertical orientation of an array of pentacil-zeolite crystals on a porous substrate. |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/234099 |
| CURRENT CPC | Separation B01D 53/864 (20130101) B01D 2255/504 (20130101) B01D 2255/9202 (20130101) B01D 2255/9205 (20130101) B01D 2255/9207 (20130101) B01D 2255/20746 (20130101) B01D 2257/702 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/75 (20130101) B01J 29/46 (20130101) Original (OR) Class B01J 35/04 (20130101) B01J 35/006 (20130101) B01J 35/1014 (20130101) B01J 35/1019 (20130101) B01J 35/1038 (20130101) B01J 37/0217 (20130101) B01J 37/0219 (20130101) B01J 37/0228 (20130101) B01J 37/0244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050983 | Harris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Rachel D. Harris (Pittsburgh, Pennsylvania); Kristi M. Allen (Pittsburgh, Pennsylvania); Elizabeth S. Brown-Tseng (Gibsonia, Pennsylvania); Justin J. Martin (Harrison City, Pennsylvania); Kuldeep Kumar (Pittsburgh, Pennsylvania); Mark W. McMillen (Cabot, Pennsylvania); Silvia Bezer (Gibsonia, Pennsylvania) |
| ABSTRACT | Disclosed herein are systems and methods for treating a metal substrate. The system includes a first pretreatment composition comprising a fluorometallic acid and free fluoride and having a pH of 1.0 to 4.0 and a second pretreatment composition comprising a Group IVB metal or a third pretreatment comprising a lanthanide series metal and an oxidizing agent. The method includes contacting at least a portion of a surface of the substrate with the first pretreatment composition and optionally contacting at least a portion of the substrate surface with the second pretreatment composition or the third pretreatment composition. Also disclosed are substrates treated with one of the systems or methods. Also disclosed are magnesium or magnesium alloy substrates comprising a bilayer comprising a first layer comprising silicone and a second layer comprising fluoride. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 17/754483 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/102 (20130101) Original (OR) Class B05D 7/14 (20130101) B05D 7/54 (20130101) B05D 2202/20 (20130101) B05D 2350/00 (20130101) B05D 2518/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051533 | Tang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Delphi Technologies IP Limited (St. Michael, Barbados) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Li Tang (Troy, Michigan); Neeraj Rama (Rochester Hills, Michigan); Peter Michael Olin (Ann Arbor, Michigan) |
| ABSTRACT | A method for controlling vehicle propulsion may include identifying at least one route characteristic of a portion of a route being traversed by a vehicle and determining a profile for a target vehicle speed based on the at least one route characteristic and a vehicle energy consumption profile. The method may also include, in response to detecting a lead vehicle, determining a vehicle speed of the lead vehicle and determining whether to avoid triggering initiation of the vehicle follow mode by the vehicle propulsion controller based on (i) a distance between the vehicle and a triggering threshold and (ii) the vehicle speed of the vehicle. The method may also include, in response to not triggering vehicle follow mode, determining, based on the vehicle speed of the lead vehicle and the profile for the target vehicle speed, a traveling distance between the vehicle and a trigger threshold. |
| FILED | Wednesday, August 10, 2022 |
| APPL NO | 17/885050 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/143 (20130101) Original (OR) Class B60W 40/105 (20130101) B60W 2554/80 (20200201) B60W 2556/10 (20200201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051829 | JASINSKI et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacek B. JASINSKI (Louisville, Kentucky); Gamini U. SUMANASEKERA (Louisville, Kentucky); Bhupendra KARKI (Louisville, Kentucky); Manthila RAJAPAKSE (Louisville, Kentucky) |
| ABSTRACT | Thermoelectric devices including Arsenic-Phos-phorous (AsxP1-x) as a source of power, wherein x is a number ranging from 0.1 to 1, are provided. Methods of making crystalline Arsenic-Phosphorous (AsxP1-x), wherein x ranges from 0.1 to 1, are also provided. The methods include annealing phosphorous and arsenic at a temperature and under conditions sufficient to produce crystalline formation. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 18/018470 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 25/08 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/50 (20130101) C01P 2002/82 (20130101) C01P 2002/90 (20130101) C01P 2004/04 (20130101) C01P 2006/32 (20130101) C01P 2006/40 (20130101) Alloys C22C 28/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/02 (20130101) C22F 1/16 (20130101) Electric solid-state devices not otherwise provided for H10N 10/01 (20230201) H10N 10/853 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051871 | Matta et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina); Battelle Savannah River Alliance, LLC (AS\iken, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina); Battelle Savannah River Alliance, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Fabio Matta (Columbia, South Carolina); Mohammed Baalousha (Columbia, South Carolina); Steven M. Serkiz (Aiken, South Carolina); Jay Gaillard (Aiken, South Carolina); Shohana Iffat (Jersey City, New Jersey) |
| ABSTRACT | Described herein are cementitious composite materials incorporating carbon nanostructures (e.g., nanotubes, nanoplatelets, nanoribbons) that are employed as amendments (i.e., admixtures or additives) to cementitious waste forms as a means to enhance radionuclide and hazardous waste (e.g., heavy metals, toxic organics) retention wherein the incorporation of well-dispersed carbon nanostructures yields more effective waste forms through the resulting modification of the cementitious composite nano-, micro-, and meso-structure (e.g., hindering the infiltration of oxygen and the leaching of waste), and the chemical interactions between chemically-affine waste molecules and the amended cementitious composite. |
| FILED | Thursday, June 08, 2023 |
| APPL NO | 18/331395 |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/33 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/024 (20130101) C04B 14/026 (20130101) C04B 18/0472 (20130101) Original (OR) Class C04B 20/023 (20130101) C04B 28/04 (20130101) C04B 28/08 (20130101) C04B 28/021 (20130101) C04B 40/0046 (20130101) C04B 2111/00784 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/165 (20130101) G21F 9/304 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052111 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ting Xu (Berkeley, California); Jie Yao (Berkeley, California); Katherine Evans (Berkeley, California); Qingjun Wang (Berkeley, California); Emma Vargo (Berkeley, California) |
| ABSTRACT | Methods for generating patterned nanoparticle assemblies in thin films of supramolecular nanocomposites are provided that allow control over microdomain morphology, periodicity, and orientation by tuning the assembly kinetics and pathways of the system. Directed self-assembly (DSA) of block copolymers (BCPs) with nanoparticles formed on lithographically-patterned templates produce patterned supramolecular nanocomposite films and patterns of nanoparticles. DSA may be used to guide the formation of concentric rings with radii spanning approximately 150 nm to 1150 nm and ring widths spanning about 30 nm to 60 nm, for example. When plasmonic nanoparticles are used, ring nanodevice arrays can be fabricated in one step, and the completed devices produce high-quality orbital angular momentum (OAM). |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/234246 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/40 (20130101) B29C 33/42 (20130101) B29C 33/3842 (20130101) B29C 39/02 (20130101) B29C 39/003 (20130101) B29C 39/36 (20130101) B29C 71/009 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00644 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2505/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/008 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/08 (20130101) C08K 5/13 (20130101) C08K 2003/0831 (20130101) C08K 2201/011 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052133 | Dou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Chang Dou (Alameda, California); Hemant Choudhary (Emeryville, California); Ning Sun (Fremont, California); Blake A. Simmons (San Francisco, California) |
| ABSTRACT | A method for depolymerizing a mixture of plastics is described. The method comprises (a) providing a composition comprising two of more plastics, (b) introducing a solvent comprising an ionic liquid (IL) or deep eutectic solvents (DES) and optionally water to the composition to form a solvent-plastic composition, such as an aqueous solvent-plastic composition, and (c) incubating the solvent-plastic composition for a period of time to produce a depolymerized composition such that at least portions of the two of more plastics are depolymerized into monomers. The produced monomers can be used as a carbon source for microbes to produce bioproducts. |
| FILED | Saturday, August 05, 2023 |
| APPL NO | 18/365973 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/16 (20130101) C08J 11/28 (20130101) Original (OR) Class C08J 2367/02 (20130101) C08J 2367/04 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052382 | Pomraning et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyle R. Pomraning (Walden, Colorado); Ziyu Dai (Richland, Washington); Jon K. Magnuson (Richland, Washington); Beth A. Hofstad (Richland, Washington); Jeffrey J. Czajka (Richland, Washington); Joonhoon Kim (Kirkland, Washington); Shuang Deng (Richland, Washington) |
| ABSTRACT | Provided herein are recombinant Aspergillus niger capable of producing 3-hydroxypropionic acid (3-HP). Also provided are methods of producing 3-hydroxypropionic acid (3-HP) and related kits. |
| FILED | Thursday, August 03, 2023 |
| APPL NO | 18/365091 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/88 (20130101) C12N 9/1096 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Original (OR) Class Enzymes C12Y 101/01059 (20130101) C12Y 206/01018 (20130101) C12Y 401/01011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052456 | Allanore et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (MIT) (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Antoine Allanore (Brentwood, New Hampshire); Caspar R. Stinn (Medford, Massachusetts) |
| ABSTRACT | In accordance with one embodiment, a method comprises dissolving a sulfide of a first metal in a solvent comprising molten aluminum; aluminothermically reduce at least a portion of the sulfide through reactive vacuum distillation to form gaseous aluminum sulfide distillate and elemental first metal that remains in the molten aluminum; and at least one of (e.g., one, two, or all three of) (a) reacting the aluminum sulfide distillate with at least one material in the molten aluminum; (b) reacting the aluminum sulfide distillate with at least one material outside of the molten aluminum; or (c) condensing the gaseous aluminum sulfide distillate. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/384722 |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 5/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052503 | Beh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Quino Energy, Inc. (Menlo Park, California); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eugene Beh (Menlo Park, California); Meisam Bahari (Alameda, California); Min Wu (Greenbelt, Maryland); Michael Aziz (Cambridge, Massachusetts); Roy Gordon (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to the synthetic functionalization of an anthraquinone molecule that is substituted with at least one hydroxyl or amino group. In some aspects of the invention a mixture containing said anthraquinone starting material, an aldehyde, a base, an optional solvent, and an optional catalyst is reacted with hydrogen and then with an oxidant. In other aspects of the invention the synthetic functionalization of the anthraquinone molecule takes place electrochemically rather than chemically, through the use of a divided electrolytic cell. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 18/257258 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/07 (20210101) Original (OR) Class C25B 3/29 (20210101) C25B 11/061 (20210101) C25B 15/083 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052862 | Whalen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott A. Whalen (West Richland, Washington); Kenneth A. Ross (West Richland, Washington); M.D. Reza-E-Rabby (Richland, Washington); Yuri Hovanski (Mapleton, Utah) |
| ABSTRACT | A method for connecting two dissimilar materials having different melting points is described wherein a the materials are heated together to obtain plasticization of the lower melting point material within a prefigured geometry within a first material in such a way so as to form intermetallic features within a solid state joint. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/494629 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/12 (20130101) B23K 20/1265 (20130101) B23K 2103/20 (20180801) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/08 (20130101) F16B 5/0012 (20130101) Original (OR) Class F16B 17/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053265 | Alden et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Caroline B. Alden (Boulder, Colorado); Robert J. Wright (Boulder, Colorado); Sean C. Coburn (Longmont, Colorado); Gregory B. Rieker (Boulder, Colorado) |
| ABSTRACT | A method for characterizing gas emissions includes sampling each of a plurality of sectors having a common geographic center. For each sector, a first laser beam is transmitted from the geographic center to a first retroreflection location, where it is retroreflected into a first retroreflected beam. Near the geographic center, the first retroreflected beam is measured to obtain a first absorption. A second laser beam is then transmitted from the geographic center to a second retroreflection location, where it is retroreflected into a second retroreflected beam. Near the geographic center, the second retroreflected beam is measured to obtain a second absorption. The first and second retroreflection locations are both located within the same sector. First and second concentrations are determined from the first and second absorptions and processed to determine emission information about a known or potential gas source whose source lies within the sector. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/268219 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) Original (OR) Class G01N 33/0075 (20130101) G01N 2021/399 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053328 | Beer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | N. Reginald Beer (Pleasanton, California); Steven W. Bond (Livermore, California) |
| ABSTRACT | The disclosed technology includes a planar device for performing multiple biochemical assays at the same time, or nearly the same time. Each assay may include a biosample including a biochemical, enzyme, DNA, and/or any other biochemical or biological sample. Each assay may include one or more tags including dyes and/or other chemicals/reagents whose optical characteristics change based on chemical characteristics of the biological sample being tested. Each assay may be optically pumped to cause one or more of luminescence, phosphorescence, or fluorescence of the assay that may be detected by one or more optical detectors. For example, an assay may include two tags and a biosample. Each tag may be pumped by different wavelengths of light and may produce different wavelengths of light that is filtered and detected by one or more detectors. The pump wavelengths may be different from one another and different from the produced wavelengths. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/470026 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) G01N 33/521 (20130101) G01N 33/525 (20130101) Original (OR) Class G01N 33/54366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053415 | Hileman et al. |
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| FUNDED BY |
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| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zachary Daniel Hileman (Manchester, New Hampshire); Daniel Homa (Blacksburg, Virginia); Gary Pickrell (Shawsville, Virginia); Eileen Martin (Denver, Colorado) |
| ABSTRACT | A magnetic field sensor in the form of a multi-material optical fiber is described. The magnetic sensing optical fiber of the present disclosure can leverage optics and magnetostriction to sense an external magnetic field adjacent to the fiber. The magnetic sensing optical fiber can be customized to achieve various desired sensing sensitivities for various applications, including measuring while drilling and unconventional oil and gas applications. In one example, an optical fiber can include a cladding that can extend from a first end to a second end of the optical fiber. The optical fiber can further include an optical core within the cladding. The optical core can extend along the optical fiber between the first end and the second end. The optical fiber can also include a magnetostrictive element within the cladding. The magnetostrictive element can extend along the optical fiber between the first end and the second end. |
| FILED | Friday, June 09, 2023 |
| APPL NO | 18/332248 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/091 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240054331 | Srinivasa |
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| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Narayan Srinivasa (San Jose, California) |
| ABSTRACT | A spiking neuromorphic network may be used to solve an optimization problem. The network may include primary neurons. The state of a primary neuron may be a value of a corresponding variable of the optimization problem. The primary neurons may update their states and change values of the variables. The network may also include a cost neuron that can compute, using a cost function, costs based on values of the variables sent to the cost neuron in the form of spikes from the primary neurons. The network may also include a minima neuron for determining the lowest cost and an integrator neuron for tracking how many computational steps the primary neurons have performed. The minima neuron or integrator neuron may determine whether convergence is achieved. After the convergence is achieved, the minima neuron or integrator neuron may instruct the primary neurons to stop computing new values of the variables. |
| FILED | Wednesday, October 18, 2023 |
| APPL NO | 18/489327 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240054399 | HONG et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| INVENTOR(S) | TAE MIN HONG (PITTSBURGH, Pennsylvania); BENJAMIN T. CARLSON (SANTA BARBARA, California); JOERG H. STELZER (CHEMNITZ, Germany); STEPHEN T. ROCHE (NAPERVILLE, Illinois); STEPHEN T. RACZ (NORTH HUNTINGDON, Pennsylvania); DANIEL C. STUMPP (NEW CUMBERLAND, Pennsylvania); QUINCY BAYER (MURRYSVILLE, Pennsylvania); BRANDON R. EUBANKS (PITTSBURGH, Pennsylvania) |
| ABSTRACT | A system for providing a boosted decision tree (BDT) for use on an electronic device to provide an event score based on a user input event, where the device includes: a machine learning trainer configured to create a trained BDT from an untrained BDT by determining parameters for the untrained BDT; a nanosecond optimizer configured to create an optimized BDT, the nanosecond optimizer including at least one of a tree flattener, a tree merger, a score normalizer, a tree remover, and a cut eraser; and a converter coupled to the nanosecond optimizer and configured to receive the optimized BDT from the nanosecond optimizer and convert the optimized BDT to a language for high-level-synthesis to produce a hardware description language representation of the optimized BDT, wherein the hardware description language representation of the optimized BDT is structured and configured to be implemented in firmware provided on the electronic device. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 18/264877 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055149 | Mandal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Krishna C. Mandal (Columbia, South Carolina); Sandeep K. Chaudhuri (Columbia, South Carolina) |
| ABSTRACT | Described herein are methods and systems for fabrication of high-performing metal-oxide-semiconductor (MOS) devices by depositing yttrium oxide epitaxial layers through pulsed laser deposition on high quality 4H—SiC epitaxial layers. The novel MOS devices revealed an extraordinarily long hole diffusion length that has never been reported. These devices have been investigated as radiation detectors which demonstrated an excellent radiation response at zero applied bias (self-biased) with a record-high energy resolution. |
| FILED | Wednesday, June 07, 2023 |
| APPL NO | 18/330749 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/24 (20130101) Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation G21H 1/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055165 | WANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian-Ping WANG (Shoreview, Minnesota); Bin MA (Roseville, Minnesota); Jinming LIU (Minneapolis, Minnesota); Yiming WU (Shoreview, Minnesota); YanFeng JIANG (Minneapolis, Minnesota) |
| ABSTRACT | Example nanoparticles may include an iron-based core, and a shell. The shell may include a non-magnetic, anti-ferromagnetic, or ferrimagnetic material. Example alloy compositions may include an iron-based grain, and a grain boundary. The grain boundary may include a non-magnetic, anti-ferromagnetic, or ferrimagnetic material. Example techniques for forming iron-based core-shell nanoparticles may include depositing a shell on an iron-based core. The depositing may include immersing the iron-based core in a salt composition for a predetermined period of time. The depositing may include milling the iron-based core with a salt composition for a predetermined period of time. Example techniques for treating a composition comprising core-shell nanoparticles may include nitriding the composition. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/494838 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/16 (20220101) B22F 1/054 (20220101) B22F 1/0547 (20220101) B22F 1/0553 (20220101) B22F 9/04 (20130101) B22F 2301/35 (20130101) B22F 2302/20 (20130101) B22F 2304/054 (20130101) Alloys C22C 38/00 (20130101) C22C 38/001 (20130101) C22C 38/10 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/26 (20130101) C23C 8/50 (20130101) C23C 8/80 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/059 (20130101) H01F 1/061 (20130101) H01F 1/065 (20130101) Original (OR) Class H01F 1/0551 (20130101) H01F 1/0552 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055650 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | Hui Wang (Louisville, Kentucky); Yang Li (Louisville, Kentucky); Thad Druffel (Louisville, Kentucky) |
| ABSTRACT | A sulfide-based composite electrolyte for use in solid-state batteries and methods for making same. In some embodiments, the sulfide-based composite electrolyte comprises the combination of an inorganic sulfide Li argyrodite (Li7PS6) with a polyvinylidenefluoride-co-hexafluoropropylene (PVDF-HFP) polymer. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 18/014919 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/056 (20130101) Original (OR) Class H01M 2300/0068 (20130101) H01M 2300/0082 (20130101) H01M 2300/0088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055680 | Diaz Aldana et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Luis A. Diaz Aldana (Idaho Falls, Idaho); Tedd E. Lister (Cotuit, Massachusetts); Aaron D. Wilson (Idaho Falls, Idaho); John R. Klaehn (Idaho Falls, Idaho); Meng Shi (Idaho Falls, Idaho) |
| ABSTRACT | A method of recovering lithium from a lithium-containing material comprises introducing a lithium-containing material to an electrochemical cell, transporting lithium ions from the lithium-containing material through a cation exchange membrane to a catholyte within a cathode chamber of the electrochemical cell, reacting the lithium ions with bicarbonate ions in the cathode chamber to form lithium carbonate, and removing the lithium carbonate from the catholyte. Related methods of recovering lithium from lithium-containing, materials, and related systems are disclosed. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 18/257786 |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 7/007 (20130101) C22B 23/0415 (20130101) C22B 26/12 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/14 (20130101) C25B 9/19 (20210101) C25B 15/083 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20240049959 | Feola |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Feola (Washington, District of Columbia) |
| ABSTRACT | Methods, systems, and apparatuses are described for causing light to be emitted, determining a physiological response, receiving, based on the physiological response, a signal, determining one or more signal features, and determining, based on the one or more signal features, a physiological condition. |
| FILED | Thursday, December 23, 2021 |
| APPL NO | 18/269473 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) Original (OR) Class A61B 5/398 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050311 | Avila |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Angel A. Avila (Santa Fe, New Mexico) |
| ABSTRACT | An apparatus for sorting pills has a body defining a plurality of receptacles. A slide plate is positioned on the body. The slide plate defines a first plurality of openings. The slide plate is slidable relative to the body about and between a first position and a second position. In the first position, the first plurality of openings are offset from respective receptacles of the plurality of receptacles so that the slide plate blocks the plurality of receptacles. In the second position, the first plurality of openings are aligned with respective receptacles of the plurality of receptacles so that pills can pass through the first plurality of openings and into the receptacles. A retaining plate retains the slide plate against the body. The retaining plate defines a slot, and the slide plate has a tab that extends through the slot and permits articulation of the slide plate. |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/449870 |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/03 (20130101) Original (OR) Class A61J 7/04 (20130101) A61J 2205/40 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 1/36 (20130101) B65D 43/16 (20130101) B65D 51/245 (20130101) B65D 83/0445 (20130101) B65D 2203/00 (20130101) B65D 2251/1058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240050436 | EL-REMESSY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States GOVERNMENT As Represented By The Department of Veterans Affairs (Washington, District of Columbia); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (STANFORD, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | AZZA EL-REMESSY (Martinez, Georgia); FRANK LONGO (Menlo Park, California) |
| ABSTRACT | Disclosed are methods of treating an ocular disease associated with retinal ischemic injury in a subject comprising administering to the subject a p75NTR modulator, a MSC comprising decreased p75NTR expression or activity or a MSC secretome collected from a MSC comprising decreased p75NTR expression or activity. Disclosed are methods of treating late stage diabetes in a subject comprising administering to the subject in need thereof a p75NTR modulator, a MSC comprising decreased p75NTR expression or activity or a MSC secretome collected from a MSC comprising decreased p75NTR expression or activity. |
| FILED | Friday, October 20, 2023 |
| APPL NO | 18/491249 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5375 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 38/1866 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/02 (20180101) A61P 13/12 (20180101) A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051965 | BERESIS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (WASHINGTON, District of Columbia) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Richard T. BERESIS (San Francisco, California); John Cijiang HE (Forest Hills, New York); Kyung LEE (Bronx, New York) |
| ABSTRACT | Disclosed is an oxygen-containing heterocyclic compound, and use thereof. The present disclosure provides an oxygen-containing heterocyclic compound represented by Formula I, a pharmaceutically acceptable salt thereof, deuterated derivative thereof, a solvate thereof, a solvate of the pharmaceutically acceptable salt thereof or a crystal form thereof, and the oxygen-containing heterocyclic compound is expected to selectively inhibit Smad3 activation. |
| FILED | Friday, August 04, 2023 |
| APPL NO | 18/365473 |
| CURRENT CPC | Heterocyclic Compounds C07D 491/052 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052056 | Weisbart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard H. Weisbart (Sepulveda, California); Robert N. Nishimura (Sepulveda, California) |
| ABSTRACT | The invention provides a method for inhibiting an intracellular target in a cell with a bispecific antibody comprising contacting the cell with a bispecific antibody having a first Fv fragment with a cell-penetrating determinant and a second Fv fragment with an intracellular target-binding determinant under suitable conditions so that the first Fv fragment causes the bispecific antibody to enter the cell and the second Fv fragment binds the intracellular target in the cell and thereby inhibiting the intracellular target. |
| FILED | Monday, June 15, 2020 |
| APPL NO | 16/902173 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/3053 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052057 | Weisbart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard H. Weisbart (Sepulveda, California); Robert N. Nishimura (Sepulveda, California) |
| ABSTRACT | The invention provides a method for inhibiting an intracellular target in a cell with a bispecific antibody comprising contacting the cell with a bispecific antibody having a first Fv fragment with a cell-penetrating determinant and a second Fv fragment with an intracellular target-binding determinant under suitable conditions so that the first Fv fragment causes the bispecific antibody to enter the cell and the second Fv fragment binds the intracellular target in the cell and thereby inhibiting the intracellular target. |
| FILED | Wednesday, May 24, 2023 |
| APPL NO | 18/322846 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/3053 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240051242 | HARIK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramy HARIK (Columbia, South Carolina); Joshua HALBRITTER (Columbia, South Carolina); Alex BRASINGTON (Columbia, South Carolina) |
| ABSTRACT | Automated Fiber Placement (AFP) manufacturing with carbon fiber composites is increasingly used for complex and/or large structures. Computer-Aided Process Planning (CAPP) software supports process planning for AFP manufacturing to assist identifying optimal starting point location and layup strategy for each laminate ply. Ply optimization functions on measurement and scoring of geometry-based defects (gaps, overlaps, angle deviation, and steering). CAPP mitigates defect stacking through the laminate thickness by generating best ply scenarios and comparing ply defects to identify regions where defects are stacking up. Stacked defects frequency and severity are described using a disclosed scoring system, so process planners can craft fiber paths that mitigate the number and compounding effect of laminate geometry-based defects. Defects can be minimized in the process planning phase by optimizing the selection of input parameters such as starting points, layup strategies, and tows per course, using surrogate-based methods. |
| FILED | Monday, August 07, 2023 |
| APPL NO | 18/366049 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/382 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/20 (20200101) G06F 2113/26 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240051830 | Gailus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nanocomp Technologies, Inc. (The Woodlands, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Gailus (Merrick, New Hampshire); Deepak VARSHNEY (Merrimack, Texas); Jonathan PHILLIPS (Los Angeles, California) |
| ABSTRACT | Two-stage reactor and method for producing carbon nanotubes. |
| FILED | Tuesday, December 21, 2021 |
| APPL NO | 18/267121 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2295 (20130101) B01J 2531/004 (20130101) B01J 2531/842 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/162 (20170801) Original (OR) Class C01B 2202/34 (20130101) C01B 2202/36 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052506 | Suzuki et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Toshio Suzuki (New Haven, Connecticut); Christian Junaedi (Cheshire, Connecticut); Subir Roychoudhury (Madison, Connecticut) |
| ABSTRACT | A metal substrate for use in a metal-supported electrochemical cell is disclosed, the substrate containing a porous metal support comprising a first metal, such as a ferritic alloy, having applied on one side thereon a barrier layer comprising a bimodal distribution of micron-sized grains of a second metal, for example, nickel, and submicron-sized grains of a metal oxide, for example, gadolinium-doped ceria. A method of fabricating the metal substrate is disclosed. A metal-supported electrode and a metal-supported electrochemical cell are fabricated with the metal substrate. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/547195 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/23 (20210101) C25B 11/031 (20210101) C25B 11/052 (20210101) C25B 11/069 (20210101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8621 (20130101) H01M 4/8803 (20130101) H01M 4/9033 (20130101) H01M 8/0232 (20130101) H01M 8/0236 (20130101) H01M 8/0245 (20130101) H01M 8/1226 (20130101) H01M 8/1253 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240052976 | Stautner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ernst Wolfgang Stautner (Niskayuna, New York); Constantinos Minas (Slingerlands, New York) |
| ABSTRACT | A cryogenic system includes a cryogenic tank containing a liquid cryogen and a vacuum vessel surrounding the cryogenic tank and providing a vacuum space between an inner surface of the vacuum vessel and an outer surface of the cryogenic tank. The cryogenic system further includes a suspension system arranged within the vacuum space so as to support the cryogenic tank within the vacuum vessel and to maintain the cryogenic tank within the vacuum vessel in a desired position. The suspension system includes a plurality of roller elements arranged within the vacuum space and contacting the inner surface of the vacuum vessel and the outer surface of the cryogenic tank. |
| FILED | Tuesday, August 09, 2022 |
| APPL NO | 17/883895 |
| CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/12 (20130101) Original (OR) Class F17C 2201/0109 (20130101) F17C 2203/0391 (20130101) F17C 2203/0629 (20130101) F17C 2205/0308 (20130101) F17C 2209/22 (20130101) F17C 2221/012 (20130101) F17C 2221/033 (20130101) F17C 2223/0161 (20130101) F17C 2265/066 (20130101) F17C 2270/0189 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240053541 | ZHANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yang ZHANG (Hyattsville, Maryland); Mario DAGENAIS (Chevy Chase, Maryland); Sylvain VEILLEUX (Chevy Chase, Maryland); Jiahao ZHAN (College Park, Maryland); Pradip GATKINE (Pasadena, California); Wei-Lun HSU (Silver Spring, Maryland) |
| ABSTRACT | An arrayed waveguide grating (AWG) can have a reusable delay line, a plurality of coupling devices, and a free propagation region (FPR). The delay line can have a continuous first waveguide connected to receive a plurality of wavelengths. Each coupling device can have a second waveguide coupled to a respective portion of the continuous first waveguide. The FPR can have input and output ends. The input end of the FPR can be coupled to receive the radiation from each of the coupling devices. The radiation can be directed to spatially-separated output channels based on wavelength at the output end of the FPR. The plurality of coupling devices and the delay line are configured to control power and phase distributions of the radiation transmitted to the FPR. |
| FILED | Tuesday, May 16, 2023 |
| APPL NO | 18/197857 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/2861 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240054329 | Liu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yongming Liu (Chandler, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Yongming Liu (Chandler, Arizona) |
| ABSTRACT | A system includes a Bayesian Spatiotemporal Graph Transformer (B-STAR) architecture that models spatial and temporal relationship of multiple agents under uncertainties. The system enables Multi-Agent Trajectory Prediction for safety-critical engineering applications, (e.g., autonomous driving and flight systems) and considers the impact of various sources, such as environmental conditions, pilot/controller behaviors, and potential conflicts with nearby aircraft. It is shown that B-STAR achieves state-of-the-art performance on the ETH/UCY pedestrian dataset with UQ competence. |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/234124 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/047 (20230101) Original (OR) Class G06N 3/049 (20130101) G06N 3/0455 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20240052414 | Szalai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Veronika Ann Szalai (Monrovia, Maryland); Jacob Michael Majikes (Gaithersburg, Maryland) |
| ABSTRACT | Embodiments of the present invention relate to methods and composition of a nucleic acid tile with addressable locations for placement of molecular species that can function as sensors, reporters, or enhancers of measurement systems. Embodiments of the present invention may also include a nucleic acid tile with addressable locations for placement of molecular species such that attachment chemistry restricts motion of the probes and permits mixing and matching of probes for multiplexed sensing and detection. |
| FILED | Wednesday, May 17, 2023 |
| APPL NO | 18/198457 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6876 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055154 | Marion et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Juliette Marion (Paris, France); Polina Olegovna ANIKEEVA (Lexington, Massachusetts); Yoel FINK (Brookline, Massachusetts) |
| ABSTRACT | An elastic and conductive fiber includes a cladding with a channel and a conductor disposed therein. The cladding may be made of a thermoplastic elastomer. The conductive fiber includes an excess length of conductor disposed inside of the channel so that the conductive fiber can stretch without applying substantial strain to the conductor and without substantially changing the electrical resistance of the conductive fiber. The conductor inside of the channel may have a buckled shape or a helical shape. |
| FILED | Friday, June 09, 2023 |
| APPL NO | 18/332326 |
| CURRENT CPC | Woven Fabrics; Methods of Weaving; Looms D03D 1/0088 (20130101) D03D 15/25 (20210101) D03D 15/30 (20210101) D03D 15/283 (20210101) D03D 15/292 (20210101) Knitting D04B 1/16 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2321/02 (20130101) D10B 2401/061 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 3/44 (20130101) H01B 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20240054628 | GONG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (COLUMBIA, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | YUFENG GONG (COLUMBIA, South Carolina); YU QIAN (IRMO, South Carolina) |
| ABSTRACT | Evaluating railway ballast fouling condition is critical to assessing track conditions and arranging proper ballast maintenance. Because fouled ballast materials with different fouling conditions have different material properties, these properties can be used to evaluate the fouling severity. Various previously developed approaches to estimating fouling conditions often require special sensors or equipment, and well-trained technicians. Recently, convolutional neural network (CNN) based computer vision approaches have performed particle segmentation to obtain ballast grain size distribution. While the coarse aggregate fraction can be evaluated, many such approaches do not segment fine particles. This disclosure is an image analysis approach to directly estimate the ballast fouling conditions. First, fouled ballast images with different fouling conditions are taken as the reference. Then, the RGB color distributions of the fouled ballast images are processed through statistical analysis. A strong linear correlation between Fouling Index (FI) and Variance is found and used to establish an FI prediction model which has been tested and validated by additional fouled ballast samples. |
| FILED | Monday, July 17, 2023 |
| APPL NO | 18/353275 |
| CURRENT CPC | Permanent Way; Permanent-way Tools; Machines for Making Railways of All Kinds E01B 35/00 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) Original (OR) Class G06T 7/90 (20170101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055603 | CRONIN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Southern California (Los Angeles, California); The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges (Stillwater, Oklahoma) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California); The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges (Stillwater, Oklahoma) |
| INVENTOR(S) | Stephen B. CRONIN (Los Angeles, California); Sisi YANG (Los Angeles, California); Özgür ÇAPRAZ (Stillwater, Oklahoma); Bertan OZDOGRU (Stillwater, Oklahoma) |
| ABSTRACT | This invention relates to alkali metal (Li, Na, K) ion batteries, electrodes for alkali metal ion batteries, and methods for manufacturing electrodes for alkali metal ion batteries. |
| FILED | Tuesday, October 05, 2021 |
| APPL NO | 18/267194 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0404 (20130101) H01M 4/583 (20130101) Original (OR) Class H01M 4/622 (20130101) H01M 4/625 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20240050251 | Bly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ZENFLOW, INC. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Austin Michael Bly (San Clemente, California); Marcel Song Sicotte (San Francisco, California); Shreya Mehta (San Francisco, California); William Martin Belef (San Francisco, California); Nicholas Damiano (San Francisco, California) |
| ABSTRACT | Systems, devices, and methods are provided for the delivery of an implant into the prostatic urethra. Embodiments of delivery systems can include a delivery device for insertion into the patient and a proximal control device for use in controlling release of the implant from the delivery device. |
| FILED | Wednesday, October 11, 2023 |
| APPL NO | 18/378940 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/005 (20130101) A61B 1/05 (20130101) A61B 1/00082 (20130101) A61B 1/00087 (20130101) A61B 1/307 (20130101) A61B 1/0676 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/966 (20130101) Original (OR) Class A61F 2/9517 (20200501) A61F 2002/047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240055648 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Navitas Systems, LLC (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pu Zhang (Ann Arbor, Michigan); Michael Wixom (Ann Arbor, Michigan); Qingliu Wu (Ann Arbor, Michigan) |
| ABSTRACT | Provided are electrode active materials with a porous structure and including a metal, that when loaded with sulfur serve as electrochemically superior cathode active materials. The metal structures are optionally used on their own, are coated with another material, or coats another porous structure such as a porous carbon structure that allows for excellent retention of both sulfur and polysulfides, are conductive themselves, and show long term stability and excellent cycle life. |
| FILED | Friday, October 20, 2023 |
| APPL NO | 18/382150 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/0402 (20130101) H01M 4/624 (20130101) H01M 4/625 (20130101) H01M 4/663 (20130101) H01M 4/808 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) Original (OR) Class H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20240054312 | SCHIMMEL |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Todd M. SCHIMMEL (Annandale, Virginia) |
| ABSTRACT | An electronic label (e-label) device that monitors situational data and displays an e-label. When the device detects an appearance modification event trigger based on the situational data, it modifies the appearance of the e-label being displayed by the e-label device, for example, by enlarging the machine-readable portion (e.g., barcode portion) of the displayed e-label. A related method and computer program product are also described. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/494061 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0717 (20130101) G06K 19/0719 (20130101) G06K 19/07707 (20130101) G06K 19/07758 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0832 (20130101) G06Q 50/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240054828 | Tartal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Albert Tartal (Baltimore, Maryland); Gabriel Michael Yessin (Arlington, Virginia); Robert E. Dalton, JR. (Greenville, South Carolina) |
| ABSTRACT | Locking systems and devices and methods for using the systems and devices are provided. A locking system may include a receptacle having a lock and an electronic credential. If the electronic credential is brought into proximity of the receptacle, then a key can be used to open the lock. The electronic credential can be incorporated into a vehicle or into a handheld device. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/496583 |
| CURRENT CPC | Locks; Accessories Therefor; Handcuffs E05B 47/026 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/00309 (20130101) Original (OR) Class G07C 9/00912 (20130101) G07C 2009/00396 (20130101) G07C 2009/00769 (20130101) G07C 2009/00968 (20130101) G07C 2209/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20240049747 | BALASUBRAMANIAM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | V. M. BALASUBRAMANIAM (Dublin, Ohio); Jerish Joyner JANAHAR (Columbus, Ohio); Rafael JIMENEZ-FLORES (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are methods of making and using, as well as products obtained by, continuous high pressure based Ultra Shear Technology (UST). These products are homogenous and stable blends of plant and animal proteins. These methods allow for the formulation and manufacture of stable liquid food products without the use of synthetic additives. The plant/animal protein blends are useful in formulating novel protein liquid foods with varied consumer applications. |
| FILED | Thursday, September 16, 2021 |
| APPL NO | 18/268072 |
| CURRENT CPC | Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/04 (20130101) A23J 3/14 (20130101) A23J 3/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 20240050953 | MCCULLOUGH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. ENVIRONMENTAL PROTECTION AGENCY (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shaun David MCCULLOUGH (Pittsboro, North Carolina); Earl PUCKETT (Durham, North Carolina) |
| ABSTRACT | A lid and a method of testing a test substance in a porous membrane insert (PMI) are dis closed, the lid including a body, sidewalls positioned along an outer perimeter of the body and configured to be seated on a shoulder of a multi-well cell culture plate, and at least one hole through the body and/or at least one knockout, wherein the lid is configured to provide the at least one hole over a corresponding well of the multi-well cell culture plate which contains the porous membrane insert. The method is a method of testing a test substance in a PMI, the method includes the steps of providing a multi-well plate with PMIs, providing the lid, removing the cover from the multi-well plate, adding the test substance, placing the lid on the multi-well cell culture plate, and conducting a manipulation of the test substance. |
| FILED | Monday, August 15, 2022 |
| APPL NO | 17/888153 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50853 (20130101) Original (OR) Class B01L 2200/14 (20130101) B01L 2200/027 (20130101) B01L 2300/0681 (20130101) B01L 2300/0829 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20240052779 | Amadon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RTX Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Colin G. Amadon (Kennebunk, Maine); Michael C. Firnhaber (East Hampton, Connecticut) |
| ABSTRACT | A stator configuration for a gas turbine engine including: a splitter segment, the splitter segment extending from a forward end to a rearward end, the splitter segment being configured to split an incoming fluid flow into a first, radially outer stream and a second, radially inner stream; a forward most first stator extending radially outwardly from the splitter segment, the forward most first stator being completely located downstream from the forward end of the splitter segment; a forward most second stator extending radially inwardly from the splitter segment, the splitter segment, the forward most first stator and the forward most second stator being formed as a single, integrally formed structure, the forward most first stator positioned closer to the forward end relative to a distance between the forward most second stator and the forward end and the forward most second stator positioned closer to the rearward end relative to a distance between the forward most first stator and the rearward end, wherein the splitter segment defines a radially outward boundary of the second, radially inner stream such that an outer tip of a rotor passes in close proximity to the splitter segment at the radially outward boundary of the second, radially inner stream defined by the splitter segment; and a sacrificial rub layer located within a pocket formed in a radially inner surface of the splitter segment that faces the outer tip of the rotor at the radially outward boundary of the second, radially inner stream defined by the splitter segment. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/171073 |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/04 (20130101) Original (OR) Class Non-positive-displacement Pumps F04D 19/002 (20130101) F04D 29/545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, February 15, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240215.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page