FedInvent™ Patent Applications
Application Details for Thursday, February 22, 2024
This page was updated on Tuesday, June 18, 2024 at 02:14 PM GMT
Department of Health and Human Services (HHS)
| US 20240057570 | Fahrenkrug et al. |
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| FUNDED BY |
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| APPLICANT(S) | Recombinetics, Inc. (Eagan, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott C. Fahrenkrug (Minneapolis, Minnesota); Daniel F. Carlson (Woodbury, Minnesota) |
| ABSTRACT | Methods, uses, and animals for introgression of alleles between animals, including SNPs. One embodiment involves introducing a targeted targeting endonuclease system and a HDR template into a cell with a mismatch in the binding of the targeting endonuclease and the targeted site. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/933367 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class Peptides C07K 14/47 (20130101) C07K 14/715 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/907 (20130101) C12N 15/8509 (20130101) C12N 15/8771 (20130101) C12N 15/8778 (20130101) C12N 2750/14143 (20130101) C12N 2800/30 (20130101) C12N 2800/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240057874 | Madabhushi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Nathaniel Braman (Bethel Park, Pennsylvania) |
| ABSTRACT | The present disclosure relates to a method. The method may be performed by accessing data derived from one or more routine clinical medical imaging scans including a lesion in which the lesion and associated vasculature are segmented in a three-dimensional segmentation. At least two features are extracted from the three-dimensional segmentation of the associated vasculature. The at least two features include at least one feature indicative of a morphology of the associated vasculature or a portion thereof, and at least one feature indicative of a function of the associated vasculature or a portion thereof. The at least two features, and/or one or more statistics of the at least two features, are provided to a machine learning model trained to make a prediction concerning the lesion. The prediction concerning the lesion is received from the machine learning model. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/495821 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/004 (20130101) A61B 5/08 (20130101) A61B 5/0035 (20130101) A61B 5/02007 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/12 (20170101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20036 (20130101) G06T 2207/20081 (20130101) G06T 2207/30061 (20130101) G06T 2207/30068 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240057892 | Kumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vivek Kumar (Bar Harbor, Maine); Keith Sheppard (Bar Harbor, Maine); Gautam Sabnis (Bar Harbor, Maine) |
| ABSTRACT | Systems and methods described herein provide techniques for analyzing gait and posture of a subject with respect to control data. The systems and methods, in some embodiments, processes video data, identifies keypoints representing body parts, determines metrics data at a stride level, and compares the metrics data to control data. |
| FILED | Wednesday, December 29, 2021 |
| APPL NO | 18/260006 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/112 (20130101) A61B 5/1116 (20130101) Original (OR) Class A61B 5/1128 (20130101) A61B 5/7267 (20130101) A61B 2503/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240057919 | Berenfeld |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
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| INVENTOR(S) | Omer Berenfeld (Ann Arbor, Michigan) |
| ABSTRACT | Techniques are provided that identify and localize on to reentrant and ectopic patterns of electrical activation in the heart wall. These patterns may correspond to atrial fibrillation, ventricular fibrillation, or other heart arrhythmia conditions. The techniques detect these patterns of electrical activity using a multi-lead an intra-cavitary catheter that, along with a controller, is able to track, over a multi-dimensional cubic space, reentrant activity and identify filaments in the heart cavity. The intra-cavitary catheter includes multiple conducting poles positioned in a configuration relative to each other and functioning as either or both sensing and active poles for measuring electrical pathways in the heart wall and over the multi-dimensional space. |
| FILED | Wednesday, November 01, 2023 |
| APPL NO | 18/386149 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/287 (20210101) Original (OR) Class A61B 5/316 (20210101) A61B 5/339 (20210101) A61B 5/361 (20210101) A61B 5/364 (20210101) A61B 5/6852 (20130101) A61B 2562/0214 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240057926 | Liew et al. |
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| APPLICANT(S) | UNIVERSITY OF SOUTHEN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHEN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Sook-Lei Liew (Los Anges, California); Octavio Marin-Pardo (Los Angeles, California); Coralie Phanord (Los Angeles, California) |
| ABSTRACT | A plurality of sensors detect neural activity and/or muscle activity of a person. A display renders an image with an avatar that represents the person. A processor moves a portion of the avatar in response to calculations performed on signals corresponding to the neural activity and the muscle activity. The avatar may be caused to move in a manner corresponding to an expected muscle movement of the person. However, due to illness or disease, the person may be unable to fully execute the expected muscle movement. By watching the avatar move in response to efforts to execute an expected muscle movement, the person may train his or her body to more fully execute desired muscle movements, such as through neurofeedback for rehabilitation. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 18/269656 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/256 (20210101) A61B 5/291 (20210101) A61B 5/296 (20210101) A61B 5/372 (20210101) A61B 5/375 (20210101) Original (OR) Class A61B 5/397 (20210101) A61B 5/744 (20130101) A61B 5/7267 (20130101) A61B 5/7455 (20130101) A61B 2560/0431 (20130101) A61B 2560/0443 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058062 | Borsic |
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| APPLICANT(S) | NE Scientific, LLC (Boston, Massachusetts) |
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| INVENTOR(S) | Andrea Borsic (Torino, Italy) |
| ABSTRACT | A system and method of modeling a necrotized tissue in an ablation procedure, the method comprising providing, at a computational component, a computer model of a volume of human tissue, simulating, by the computational component, an ablation site in the computer model, determining, by the computational component, a deposited power density relating to at least an ablation parameter using at least an ablation mode, determining, by the computational component, a heat distribution at the ablation site as a function of the deposited power density, and identifying, by the computational component, a volume of tissue necrotized during an ablation procedure performed at the ablation site. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 18/267169 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 34/10 (20160201) Original (OR) Class A61B 90/37 (20160201) A61B 2018/00577 (20130101) A61B 2034/104 (20160201) A61B 2034/105 (20160201) A61B 2034/107 (20160201) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/62 (20170101) G06T 19/003 (20130101) G06T 19/20 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058103 | Swanson et al. |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
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| INVENTOR(S) | William Benton Swanson (Ann Arbor, Michigan); Seth Woodbury (Ann Arbor, Michigan); Yuji Mishina (Ann Arbor, Michigan) |
| ABSTRACT | The disclosure relates generally to a tissue engineering matrix with improved clinical handling properties, designed for periodontal and craniofacial regeneration applications and methods of manufacturing the same. In one application, these matrices are fabricated as surgical membranes which serve not only as a protective barrier but also to induce regeneration through controlled release of inductive substances, facilitate regeneration through the tissue integration, and define and maintain dimensional stability in horizontal and/or vertical defects. In another application, these matrices are fabricated as macroporous scaffolds, and the novel chemistry serves to deliver a three-dimensional environment capable of facilitating tissue ingrowth, vascularization, extracellular matrix deposition and remodeling, and tissue regeneration. |
| FILED | Friday, April 28, 2023 |
| APPL NO | 18/141138 |
| CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 8/0006 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/041 (20130101) A61L 31/148 (20130101) A61L 2400/12 (20130101) A61L 2430/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058119 | Tranquillo et al. |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
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| INVENTOR(S) | Robert Tranquillo (Arden Hills, Minnesota); Zeeshan Syedain (Minneapolis, Minnesota) |
| ABSTRACT | A novel prosthetic valve is described herein, as well as methods of making such novel prosthetic valves. |
| FILED | Monday, February 27, 2023 |
| APPL NO | 18/114881 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2415 (20130101) Original (OR) Class A61F 2220/0058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058199 | AGRAWAL et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Sunil K. AGRAWAL (Newark, Delaware); Danielle STRAMEL (New York, New York); Jesus Antonio PRADO DE LA MORA (New York, New York) |
| ABSTRACT | Rehabilitation or ambulation assistance can be provided to a user by sensing at least one first pressure beneath the user's right foot, sensing at least one second pressure beneath the user's left foot, and predicting the user's gait based on the sensed at least one first pressure and the sensed at least one second pressure. A plurality of motors are energized at a plurality of times that are synchronized with phases of the user's gait so that the plurality of motors pull on respective cables at respective times in a coordinated sequence. Each of the cables has a first end affixed to a pelvic belt or harness that is shaped and dimensioned to fit securely on the user's pelvis, and the timing of the energizing is based on the gait predictions. |
| FILED | Wednesday, August 16, 2023 |
| APPL NO | 18/234482 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0244 (20130101) A61H 3/04 (20130101) Original (OR) Class A61H 2003/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058283 | Barnett et al. |
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| APPLICANT(S) | West Virginia University Board of Governors on Behalf of West Virginia University (Morgantown, West Virginia); Temple University-Of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania); University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John B. Barnett (Morgantown, West Virginia); Werner Geldenhuys (Morgantown, West Virginia); Jonathan Soboloff (Philadelphia, Pennsylvania); Harry C. Blair (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of restoring the balance of osteoclast to osteoblast activity in a patient having rheumatoid arthritis comprising administering to a patient a therapeutically effective amount of the compound N-(3,4-dichlorophenyl)-N-methylpropanamide is provided. A method for treating arthritis-induced bone erosion in a patient comprising administering to a patient a therapeutically effective amount of the compound N-(3,4-dichlorophenyl)-N-methylpropanamide is provided. The compound N-(3,4-dichlorophenyl)-N-methylpropanamide is administered in a pharmaceutically acceptable composition to said patient. A mode of action of N-(3,4-dichlorophenyl)-N-methyl propanamide comprising targeting transient receptor potential channels is provided. |
| FILED | Friday, June 16, 2023 |
| APPL NO | 18/336712 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058299 | Serebrenik et al. |
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| APPLICANT(S) | Humanetics Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Artur A. Serebrenik (Philadelphia, Pennsylvania); Michael D. Kaytor (Maplewood, Minnesota); John C. Dykstra (Edina, Minnesota); Ronald J. Zenk (Shorewood, Minnesota); Brett D. Anderson (Minneapolis, Minnesota) |
| ABSTRACT | Methods and materials and methods for reducing organ and tissue damage associated with inflammatory and immunological disorders are provided herein. For example, this document provides methods and materials for using genistein to treat respiratory distress syndrome or acute lung injury (e.g., pneumonitis, pulmonary fibrosis, dyspnea, pneumonia, and/or pulmonary edema resulting from viral infection, allergic responses, chemical insults, radiation, tissue injury, persistent infections, or autoimmune reactions). |
| FILED | Tuesday, January 11, 2022 |
| APPL NO | 18/271125 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) Original (OR) Class A61K 47/32 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058308 | Miller |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
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| INVENTOR(S) | Jason Miller (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are methods for the treatment and prevention of dry macular degeneration via the pharmacologic activation of autophagy without direct inhibition of mammalian target of rapamycin (mTOR), for example by administration of flubendazole. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 18/260919 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058310 | Soboloff et al. |
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| APPLICANT(S) | Temple University-Of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Soboloff (Philadelphia, Pennsylvania); M. Raza Zaidi (Philadelphia, Pennsylvania); Scott Gross (Philadelphia, Pennsylvania); John Elrod (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention comprises methods for treating diseases or disorders associated with reduced levels of Ca2+ signaling, including melanoma and other cancers. |
| FILED | Tuesday, June 06, 2023 |
| APPL NO | 18/329957 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/426 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058318 | Goetz et al. |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew P. Goetz (Rochester, Minnesota); Thomas R. Caulfield (Jacksonville, Florida); John Randolph Hawse, IV (Rochester, Minnesota) |
| ABSTRACT | Methods and material for treating cancer (e.g., estrogen receptor negative (ER−) and estrogen receptor positive (ER+) breast cancer) are described herein. For example, methods and materials for targeting degradation of protein kinase C type beta (PKCβ1) polypeptides in mammals with ER− cancers are described. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 18/266375 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/138 (20130101) A61K 31/452 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058335 | PENDERGAST et al. |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Ann Marie PENDERGAST (Durham, North Carolina); Jillian HATTAWAY LUTTMAN (Durham, North Carolina) |
| ABSTRACT | The present disclosure describes, in part, methods of preventing and/or treating cancer in a subject by co-administering an ABL inhibitor and a mevalonate pathway inhibitor. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 18/270613 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/366 (20130101) A61K 31/405 (20130101) A61K 31/505 (20130101) Original (OR) Class A61K 31/506 (20130101) A61K 31/4439 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058340 | Vernier et al. |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Erasca, Inc. (San Diego, None) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jean-Michel Vernier (San Diego, California); David A. Nathanson (Los Angeles, California); Michael E. Jung (Los Angeles, California); Timothy F. Cloughesy (Calabasas, California); Lorenz Urner (Los Angeles, California); Peter M. Clark (Los Angeles, California); Jonathan Tsang (Los Angeles, California) |
| ABSTRACT | The present disclosure relates to compounds that are capable penetrating to the blood brain barrier to modulate the activity of EGFR tyrosine kinase. The disclosure further relates to methods of treating glioblastoma and other EGFR mediated cancers. The disclosure further relates to methods of treating glioblastoma and other EGFR mediated cancers that have been determined to have altered glucose metabolism in the presence of inhibitors. The present disclosure also provides methods of administering to a subject a glucose metabolism inhibitor and a cytoplasmic p53 stabilizer. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 18/027313 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 31/551 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Heterocyclic Compounds C07D 491/056 (20130101) C07D 519/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/66 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058344 | Orr et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (lthaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam Orr (Briarcliff Manor, New York); Anna Orr (Briarcliff Manor, New York) |
| ABSTRACT | Disclosed herein are methods of treating or preventing neurodegenerative disease, neuronal damage, neuroinflammation, or cancer using suppressors of electron leak. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 18/268102 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/343 (20130101) A61K 31/385 (20130101) A61K 31/426 (20130101) A61K 31/498 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058349 | Budunova |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Irina Budunova (Chicago, Illinois) |
| ABSTRACT | Provided herein are methods of treating and preventing steroid-induced atrophy (e.g., skin atrophy, osteoporosis, etc.) by the administration of PI3K/Akt/mTOR inhibitors and pharmaceutical compositions and combinations therefor. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/257261 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/573 (20130101) A61K 31/585 (20130101) A61K 31/5377 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) A61P 19/10 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058367 | Desimone et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Joseph Desimone (Glen Ellyn, Illinois); Yogen Saunthararajah (Cleveland, Ohio) |
| ABSTRACT | Embodiments of compositions and methods for the treatment of blood disorders and malignancies in a subject are described herein. In one embodiment, a composition for the treatment of a blood disorder or a malignancy in a subject comprises decitabine, tetrahydrouridine, and an excipient. In another embodiment, a method for the treatment of a blood disorder or a malignancy in a subject comprises the oral administration of a composition comprising decitabine and tetrahydrouridine. In some examples, the composition may be administered 1-3 times weekly. |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/239460 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058375 | ZHOU et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Qi ZHOU (West Lafayette, Indiana); Maizbha Uddin AHMED (West Lafayette, Indiana); Mohammad Abul Kalam AZAD (Melton South, Australia); Jian LI (Carnegie, Victoria, Australia) |
| ABSTRACT | The present disclosure generally relates to a method for reducing the toxicity of polymyxins as a therapeutic agent comprising the step of coadministration of an aminoglycoside; a method for improving the aerosolization of an aminoglycoside comprising the step of combination formulation with a polymyxin; and a process for manufacturing a dry powder composition comprising a polymyxin and aminoglycoside. Pharmaceutical compositions and methods of treatment for lung infections are within the scope of this invention. |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 18/260190 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0073 (20130101) A61K 9/0075 (20130101) A61K 31/785 (20130101) Original (OR) Class A61K 38/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058382 | Rao et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); City of Hope (Duarte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Masaru P. Rao (Riverside, California); Harish G. Dixit (San Jose, California); Hideaki Tsutsui (Riverside, California); Morgan L. Dundon (Riverside, California); Pranee I. Pairs (Riverside, California); Stephen J. Forman (Duarte, California); Christine E. Brown (Duarte, California); Renate Starr (Duarte, California); Christopher B. Ballas (Palmyra, New Jersey) |
| ABSTRACT | Intracellular delivery of a genetic construct to immune cells including: obtaining a deterministic mechanoporation (DMP) platform that includes a substrate having a surface and a plurality of capture sites, each said capture site having a boundary shape at the surface adapted and configured to support thereon a cell, and each said capture site having a bottom and including a sub-micron-scale projection extending from the bottom toward the surface of the substrate, wherein said projection is adapted and configured to penetrate a cell membrane and/or wall of the cell, and wherein the substrate has a plurality of aspiration vias situated at the bottom of the capture sites; introducing the cells to the surface in a liquid media; capturing the cells within the capture sites by applying a first hydrodynamic force; applying a second hydrodynamic force on the captured cell and locally rupturing the membrane and/or wall of the cell with the projection, introducing the genetic construct into the cells, and releasing the porated cells from the capture sites. Also disclosed are methods of chimeric antigen receptor (CAR) T cell adoptive immunotherapy and T cell receptor (TCR) therapy. |
| FILED | Monday, October 30, 2023 |
| APPL NO | 18/497798 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/17 (20130101) Original (OR) Class Peptides C07K 14/7051 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 15/87 (20130101) C12N 15/111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058388 | Vasudevan |
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| FUNDED BY |
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| APPLICANT(S) | The McLean Hospital Corporation (Belmont, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anju Vasudevan (Waltham, Massachusetts) |
| ABSTRACT | Described herein are methods for generating human forebrain endothelial cells, compositions comprising the cells, and methods of use thereof in therapy. Provided herein are methods for generation of human embryonic forebrain-like endothelial cells (e.g., periventricular endothelial cells) from human embryonic stem cells; the methods include addition or GABA and WNT7A for efficient differentiation, and isolation of GABRB37CD31+ cell population by FACS. |
| FILED | Monday, October 19, 2020 |
| APPL NO | 17/769647 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/24 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 2501/115 (20130101) C12N 2501/165 (20130101) C12N 2501/415 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058390 | CHEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
| ASSIGNEE(S) | The Administrators of the Tulane Educational Fund (New Orleans, Louisiana) |
| INVENTOR(S) | YiPing CHEN (Harahan, Louisiana); Zhi LIU (Chengdu, China PRC); Tian CHEN (Chengdu, China PRC); Sicheng ZHANG (Chengdu, China PRC) |
| ABSTRACT | The invention relates to the discovery of a previously unknown population of adipocytes marked by active intracellular Wnt/β-catenin signaling. The present invention provides methods of making populations of adipocytes in which the proportion of these “Wnt+ adipocytes” is much higher than those in naturally occurring populations. Wnt+ adipocytes can be used to improve blood glucose control and exosomes secreted by Wnt+ adipocytes can be administered to reduce blood glucose levels in subjects in need thereof. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/266986 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 35/35 (20130101) Original (OR) Class A61K 38/28 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0653 (20130101) C12N 2506/1353 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058401 | Steinmetz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California); Karin L. Lee (Cleveland, Ohio) |
| ABSTRACT | A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle. |
| FILED | Tuesday, February 28, 2023 |
| APPL NO | 18/115066 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 35/76 (20130101) Original (OR) Class A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058416 | Yeo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Yoon Yeo (West Lafayette, Indiana); Simseok Yuk (Chicago, Illinois) |
| ABSTRACT | The present invention generally relates to a process of nanoparticle formulations and its composition matter for systemic treatment of sepsis. In particular, this invention discloses a method for preparing tannic acid-ferric nanoparticles, optionally incorporating a component of vitamin D3, coated with zwitterionic chitosan (ZWC) and polymyxin B (PMB). The invention described herein also pertains to pharmaceutical compositions and methods for the treatment of sepsis. |
| FILED | Wednesday, November 01, 2023 |
| APPL NO | 18/499534 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 31/7032 (20130101) A61K 33/26 (20130101) A61K 38/12 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/36 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058425 | Gersbach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles A. Gersbach (Chapel Hill, North Carolina); Alejandro Barrera (Durham, North Carolina); Tyler S. Klann (Durham, North Carolina); Maria ter Weele (Durham, North Carolina); Gregory E. Crawford (Chapel Hill, North Carolina); Timothy E. Reddy (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are compositions and methods for targeting a novel regulatory element of a gene. The compositions may be used in methods of modifying growth of a cell, decreasing cell fitness, increasing cell fitness, and/or treating cancer such as leukemia. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/180718 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 38/465 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0694 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 15/907 (20130101) C12N 15/1082 (20130101) C12N 2310/20 (20170501) C12N 2740/15043 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058439 | BAKER, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James R. BAKER, Jr. (Ann Arbor, Michigan); Anna U. BIELINSKA (Ann Arbor, Michigan); Douglas SMITH (Ann Arbor, Michigan); Paul E. MAKIDON (Ann Arbor, Michigan); Jessica J. O'KONEK (Ann Arbor, Michigan) |
| ABSTRACT | The present invention provides methods and compositions for the stimulation of immune responses and for treating or preventing allergic disease and responses and inflammatory disease and responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses that prevent or treat allergic disease by reducing allergic response. Compositions and methods of the invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications. |
| FILED | Tuesday, October 03, 2023 |
| APPL NO | 18/376135 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 9/143 (20130101) A61K 9/1075 (20130101) A61K 39/35 (20130101) Original (OR) Class A61K 39/292 (20130101) A61K 47/22 (20130101) A61K 47/26 (20130101) A61K 47/44 (20130101) A61K 2039/57 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058448 | Borden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. Borden (Boulder, Colorado); Traci D. Reusser (Superior, Colorado) |
| ABSTRACT | The present invention includes system, methods, and compositions for the generation of novel oxygen microbubbles, and in particular oxygen microbubbles with a longer acyl-chain phospholipid for increased circulation persistence and oxygen payload. The novel oxygen microbubbles of the invention may be particularly suited for the treatment of tumor hypoxia in radiation oncology. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/766376 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 41/0033 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/24 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) A61N 7/00 (20130101) A61N 2005/1098 (20130101) A61N 2007/0039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058453 | Boyan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Virginia Commonwealth University (Richmond, Virginia); Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Barbara D. Boyan (Henrico, Virginia); Zvi Schwartz (Henrico, Virginia); David J. Cohen (Richmond, Virginia); Jingyao Deng (Richmond, Virginia); David Scott Wilson (Baltimore, Maryland) |
| ABSTRACT | Provided herein is a copper-free, non-toxic click hydrogel that exhibits minimal swelling. The hydrogel may be used as a sealant and/or as a delivery vehicle for local administration of substances of interest, such as therapeutic agents. |
| FILED | Thursday, August 03, 2023 |
| APPL NO | 18/364891 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 31/05 (20130101) A61K 31/7036 (20130101) A61K 38/14 (20130101) A61K 38/1774 (20130101) A61K 47/10 (20130101) A61K 47/22 (20130101) A61K 47/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058475 | Hajjar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sardocor Corp. (Lexington, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roger J. Hajjar (Lexington, Massachusetts); Ronald A. Li (Hong Kong, China Hong Kong); On Tik Wong (Hong Kong, China Hong Kong) |
| ABSTRACT | Some embodiments of the methods and compositions provided herein relate to treating, inhibiting or ameliorating a skeletal muscular dystrophy with a polynucleotide encoding a SERCA2a polypeptide. In some embodiments, the muscular dystrophy comprises Duchenne muscular dystrophy (DMD) or Becker's muscular dystrophy (BMD). In some embodiments, the polynucleotide comprises a viral vector, such as an adeno-associated viral (AAV) vector. More embodiments include methods and compositions to screen for a therapeutic agent to treat, inhibit or ameliorate a skeletal muscular dystrophy in which the screen comprises an in vitro ventricular cardiac tissue model. |
| FILED | Thursday, January 06, 2022 |
| APPL NO | 18/260456 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058533 | PATEK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Stephen D. PATEK (Charlottesville, Virginia); Basak OZASLAN (Charlottesville, Virginia); Linda GONDER-FREDERICK (Charlottesville, Virginia) |
| ABSTRACT | An insulin device configured to control insulin dispensing based on insulin sensitivity. The insulin device includes a processor configured to receive insulin dosing schedule information, psychological stress level data, and body mass index (BMI) data; a sensor configured to generate a blood glucose level measurement. The sensor is calibrated as a function of the psychological stress level data and the BMI data and the processor is configured to monitor and detect changes of the blood glucose level measurement that are determined to have occurred as a function of changes of the psychological stress level data, and identify a time when the BMI data counteracts a detected change in the blood glucose level measurement. The insulin device also includes an insulin dispensing valve controlled by the processor to change the insulin dosing schedule information in accordance with the counteracting BMI data. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/495390 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 5/14276 (20130101) A61M 2205/3553 (20130101) A61M 2205/3569 (20130101) A61M 2205/3584 (20130101) A61M 2230/201 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) G16H 50/30 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058580 | VISWANATHAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Akila VISWANATHAN (Baltimore, Maryland); Yue CHEN (Fayetteville, Arkansas); Anthony GUNDERMAN (Fayetteville, Arkansas); Henry R. HALPERIN (Baltimore, Maryland); Ehud J. SCHMIDT (Towson, Maryland); Ryan BAUMGAERTNER (Baltimore, Maryland); Marc MORCOS (Baltimore, Maryland) |
| ABSTRACT | A substantially metallic magnetic resonance Imaging (MRI)-tracked injection needle device is disclosed. The magnetic resonance Imaging (MRI)-tracked injection needle device includes a luer syringe; an electrical connector that is at least partially housed in an interior space of a distal end of the luer syringe; an electrical adaptor coupled to the electrical connector; and an injection needle comprising a shaft having a needle distal end and a needle proximal end, the shaft comprising concentric metal tubes comprising an inner metal tube and an outer metal tube, the needle proximal end coupled to the electrical adaptor and the needle distal end comprising one or more tracking coils arranged between the inner metal tube and the outer metal tube. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 18/257189 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/329 (20130101) A61M 25/06 (20130101) A61M 25/0105 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1007 (20130101) A61N 5/1027 (20130101) A61N 5/1049 (20130101) A61N 2005/1055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058625 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qifa Zhou (Arcadia, California); Mark S. Humayun (Los Angeles, California); Gengxi Lu (Los Angeles, California) |
| ABSTRACT | Present implementations can include a high-precision neural stimulation device with a high voltage ASIC with an array of transmit control cells, a 2D array of ultrasound transducers, and a coupling for interfacing the high voltage ASIC to the 2D array, where the high voltage ASIC is disposed to receive and store programmable voltage levels. A contact lens structure can include the high-precision neural stimulation device and one or more fluid channels at least partially surrounding the high-precision neural stimulation device. |
| FILED | Friday, June 16, 2023 |
| APPL NO | 18/210978 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0026 (20130101) Spectacles; Sunglasses or Goggles Insofar as They Have the Same Features as Spectacles; Contact Lenses G02C 11/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058806 | Berthier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tasso, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erwin Berthier (Seattle, Washington); Ben Casavant (Seattle, Washington); Emily Welch (Seattle, Washington); Joe Himmelheber (Seattle, Washington) |
| ABSTRACT | The disclosed apparatus, systems and methods relate to sample preparation and shipping technologies in a single shippable container. The shipping container contains a single use centrifuge. The centrifuge can be temperature controlled and meets all standards and regulations for the shipping and transport of biological specimens. |
| FILED | Wednesday, May 03, 2023 |
| APPL NO | 18/311347 |
| CURRENT CPC | Separation B01D 21/262 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50 (20130101) Original (OR) Class B01L 2200/185 (20130101) B01L 2300/023 (20130101) Centrifuges B04B 5/0414 (20130101) B04B 7/02 (20130101) B04B 13/00 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 59/04 (20130101) B65D 77/0426 (20130101) B65D 77/0453 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059646 | McAllister et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sutter Bay Hospitals (San Francisco, California); Organix, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sean D. McAllister (Milbrae, California); Pierre-Yves Desprez (Richmond, California); Anuradha Mahadevan (Westford, Massachusetts); Ravi K. Ujjinamatada (Lexington, Massachusetts) |
| ABSTRACT | The disclosure provides for resorcinol-based compounds, pharmaceutical compositions made therefrom, and methods of treatment thereof for various disorders, including neoplastic disorders. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/266771 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Acyclic or Carbocyclic Compounds C07C 235/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059655 | ZHOU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jia ZHOU (Galveston, Texas); John A. ALLEN (Galveston, Texas); Pingyuan WANG (Galveston, Texas); Daniel E. FELSING (Galveston, Texas) |
| ABSTRACT | Embodiments are directed to novel GPR52 activators. In particular, a series of novel 1-(pyrimidin-4-yl)indoline-4-carboxamide analogs that have been identified as potent and selective GPR52 agonists. The optimized GPR52 agonist that, for example, can be used as a valuable pharmacological tool or a drug candidate for investigating the physiological and therapeutic potential of GPR52 activation for various human diseases. |
| FILED | Sunday, August 27, 2023 |
| APPL NO | 18/238510 |
| CURRENT CPC | Heterocyclic Compounds C07D 213/74 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 403/04 (20130101) C07D 403/14 (20130101) C07D 405/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059656 | YU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jin-Quan YU (San Diego, California); Zhen WANG (San Diego, California); Zhen LI (San Diego, California) |
| ABSTRACT | Disclosed herein is a process for making a compound of formula (2) by (hetero)aromatic C—H hydroxylation of a compound of formula (1): catalyzed by palladium(II) and a bidentate ligand in the presence of O2. The process is useful for instance, in the late-stage modification of medicinally important heterocycles. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 18/256680 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/373 (20130101) C07C 227/10 (20130101) C07C 231/12 (20130101) C07C 303/40 (20130101) Heterocyclic Compounds C07D 209/08 (20130101) C07D 209/26 (20130101) C07D 209/86 (20130101) C07D 213/55 (20130101) C07D 213/61 (20130101) C07D 213/69 (20130101) C07D 213/74 (20130101) C07D 213/643 (20130101) C07D 213/803 (20130101) Original (OR) Class C07D 215/48 (20130101) C07D 215/50 (20130101) C07D 235/20 (20130101) C07D 241/42 (20130101) C07D 271/06 (20130101) C07D 277/64 (20130101) C07D 295/155 (20130101) C07D 307/79 (20130101) C07D 307/91 (20130101) C07D 319/18 (20130101) C07D 333/54 (20130101) C07D 333/76 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0066 (20130101) Peptides C07K 5/06078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059664 | Zaveri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Astraea Therapeutics, LLC (Mountain View, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nurulain Zaveri (Saratoga, California); Dennis Yasuda (Campbell, California) |
| ABSTRACT | The present invention provides novel piperidinyl-containing nociceptin receptor ligand compounds and pharmaceutical compositions useful in the treatment of neurological diseases and conditions where such ligands mediate the negative effects of the condition. Such neurological diseases and conditions include acute and chronic pain, substance abuse/dependence, alcohol addiction, anxiety, depression, sleep disorders, gastrointestinal disorders, renal disorders, cardiovascular disorders and Parkinson's disease. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/370145 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 405/14 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059709 | WILLIAMS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado); CETYA THERAPEUTICS, INC. (Fort Collins, Colorado) |
| ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado); CETYA THERAPEUTICS, INC. (Fort Collins, Colorado) |
| INVENTOR(S) | Robert M. WILLIAMS (Ft. Collins, Colorado); Sivanagireddy KOTI (Ft. Collins, Colorado); Subhadip DE (Ft. Collins, Colorado); Anil M. SHELKE (Ft. Collins, Colorado); Ryan E. CERBONE (Ft. Collins, Colorado); Nobuyoshi YASUDA (Ft. Collins, Colorado) |
| ABSTRACT | Disclosed are various synthetic methods to prepare structural analogs of largazole and derivatives thereof. One structural analog is an amide isostere of largazole. Another structural analog replaces the thiazole ring of largazole with a pyridine moiety or an oxazole moiety. Also disclosed are various intermediate compounds obtained when preparing structural analogs of |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/255969 |
| CURRENT CPC | Heterocyclic Compounds C07D 513/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059726 | Oyelere et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adegboyega Oyelere (Atlanta, Georgia); Subhasish Tapadar (Atlanta, Georgia); Bocheng Wu (Atlanta, Georgia) |
| ABSTRACT | Provided herein are glycosylated compounds as histone deacetylase (HDACi) inhibitors or a diastereomer, solvate, or a pharmaceutically acceptable salt thereof. Also provided are pharmaceutical compositions and medicaments that include the compounds described herein as well as methods of treating inflammatory disease and cancer. |
| FILED | Tuesday, December 28, 2021 |
| APPL NO | 18/266438 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/26 (20130101) C07H 15/203 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060039 | XUE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | XUFENG XUE (Ann Arbor, Michigan); JIANPING FU (Ann Arbor, Michigan); HUAIJING TANG (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure provides devices and in vitro methods of developing three-dimensional neural tube-like tissues. In some aspects, the disclosure provides devices and methods of developing three-dimensional neural tube-like tissues comprising forebrain-like, midbrain-like, hindbrain-like, and spinal cord-like tissues. In particular, provided herein microfluidic devices and methods of using the same for generating neural tube-like tissues, such as neural-tube like tissues comprising forebrain-like, midbrain-like, hind-brain-like, and spinal cord-like tissues. In some embodiments, uses of such neural tube-like tissues for research, compound screening and analysis, disease modeling, and therapeutics are provided. |
| FILED | Thursday, November 04, 2021 |
| APPL NO | 18/035222 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) C12M 25/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0618 (20130101) Original (OR) Class C12N 5/0697 (20130101) C12N 2513/00 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060091 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation Research (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, incorporation (Gainesville, Florida) |
| INVENTOR(S) | Eric Tzy-Shi Wang (Gainesville, Florida); Chase P. Kelley (Gainesville, Florida) |
| ABSTRACT | Autoregulatory systems that have been implemented to control the expression and activity of Cast 3d, including the activity of Cast 3d in vivo, thereby reducing collateral damage in cells at off-target sites (e.g., non-target messenger RNA transcripts. The autoregulatory system is in the form of a nucleic acid molecule comprising a zinc finger binding site, a promoter, and a nucleotide sequence encoding a Cast 3d fusion protein, and a transcriptional repressor domain, and wherein the Cast 3d fusion protein binds to the zinc finger binding site and represses transcription of the nucleotide sequence encoding the Cast 3d fusion protein. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 18/267144 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2750/14143 (20130101) C12N 2800/80 (20130101) C12N 2820/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240060115 — METHODS AND SYSTEMS FOR DETERMINING SPATIAL PATTERNS OF BIOLOGICAL TARGETS IN A SAMPLE
| US 20240060115 | Chee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| ASSIGNEE(S) | Prognosys Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Mark S. Chee (San Diego, California); David A. Routenberg (San Diego, California) |
| ABSTRACT | The present disclosure provides methods and assay systems for use in spatially encoded biological assays, including assays to determine a spatial pattern of abundance, expression, and/or activity of one or more biological targets across multiple sites in a sample. In particular, the biological targets comprise proteins, and the methods and assay systems do not depend on imaging techniques for the spatial information of the targets. The present disclosure provides methods and assay systems capable of high levels of multiplexing where reagents are provided to a biological sample in order to address tag the sites to which reagents are delivered; instrumentation capable of controlled delivery of reagents; and a decoding scheme providing a readout that is digital in nature. |
| FILED | Friday, November 03, 2023 |
| APPL NO | 18/501523 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060138 | van't Veer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laura J. van't Veer (San Francisco, California); Denise Wolf (San Francisco, California); Christina Yau (San Francisco, California); Laura Esserman (San Francisco, California) |
| ABSTRACT | The disclosure describes a tumor subtyping schema for selection of therapies to treat Stage II and Stage III breast cancers. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/174491 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060141 | Velculescu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victor Velculescu (Glenwood, Maryland); Robert B. Scharpf (Baltimore, Maryland); Dimitrios Mathios (Baltimore, Maryland); Jillian A. Phallen (Baltimore, Maryland); Daniel Bruhm (Baltimore, Maryland); Stephen Cristiano (Blatimore, Maryland) |
| ABSTRACT | Cell free DNA (cfDNA) fragmentation for lung cancer detection is combined with current imaging-based screening methods and biomarkers. |
| FILED | Tuesday, December 21, 2021 |
| APPL NO | 18/268893 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/10 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060863 | WESTPHALL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Michael WESTPHALL (Fitchburg, Wisconsin); Joshua COON (Middleton, Wisconsin) |
| ABSTRACT | The present invention provides an improved technique for cryogenically fixing biological samples in amorphous ice for analysis by cryo-electron microscopy (cryo-EM). Analyte particles are cooled to very low temperatures prior to depositing the particles onto a cooled substrate surface, such as a transmission electron microscope (TEM) grid. This approach “locks” in the particle structure prior to deposition. Either concurrently with or after deposition, the analyte particles are further contacted with a vapor stream of atoms or molecules at cryogenic or near cryogenic temperatures. As a result, a thin layer of an amorphous solid is formed around each particle without significant conformational changes in the particle structure, thereby forming an improved sample for EM analysis. |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 18/261267 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) Original (OR) Class G01N 1/2813 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060961 | Tkachenko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); CELLDOM, Inc. (San Carlos, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eugene Tkachenko (Del Mar, California); Natalia Tkachenko (Del Mar, California); Edgar Gutierrez (Spring Valley, California); Alexander Groisman (San Diego, California) |
| ABSTRACT | Provided are methods and compositions for cell-based drug screening with high-density arrays of conical microwells and slow-drug-release beads. |
| FILED | Monday, October 30, 2023 |
| APPL NO | 18/497955 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 3/50853 (20130101) B01L 2200/0668 (20130101) B01L 2200/0689 (20130101) B01L 2300/021 (20130101) B01L 2300/123 (20130101) B01L 2300/0893 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/585 (20130101) G01N 33/5008 (20130101) Original (OR) Class G01N 33/54306 (20130101) G01N 2500/02 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060962 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Bo Sun (Corvallis, Oregon); Pedram Esfahani (Corvallis, Oregon) |
| ABSTRACT | Disclosed herein are embodiments of cell culture assays for simultaneous study of chemical and mechanical cues. Also disclosed herein are extracellular matrices for use with the cell culture assays. In some examples, the extracellular matrices can have a textured fibrous structure. Also disclosed herein are embodiments of a modular apparatus for forming the cell culture assays and the extracellular matrices used with the cell culture assays. Methods for using the cell culture assays are also disclosed herein. |
| FILED | Thursday, August 10, 2023 |
| APPL NO | 18/448091 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/42 (20130101) C12M 23/48 (20130101) C12M 25/04 (20130101) C12M 41/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 2513/00 (20130101) C12N 2533/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240060964 — COORDINATELY-ORDERED SINGLE CELLS WITH INDIVIDUAL IDENTITIES FOR HIGH-THROUGHPUT ASSAY
| US 20240060964 | Su et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ming Su (Newton, Massachusetts); Qingxuan Li (Boston, Massachusetts); Liyuan Ma (Newton, Massachusetts); Sidi A. Bencherif (Boston, Massachusetts); Thibault Colombani (Boston, Massachusetts) |
| ABSTRACT | Disclosed is a technology for assaying individual cells, in which the identity of each individual cell in an ordered array is determined from coordinates assigned to it, and can be readout at high throughput with microscope. The method is able to test responses of millions of identical cells in multiple chemical and physical processes with superior statistics power to facilitate deep data mining. |
| FILED | Friday, November 03, 2023 |
| APPL NO | 18/501437 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 41/36 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) G01N 21/6428 (20130101) G01N 27/02 (20130101) G01N 33/505 (20130101) Original (OR) Class G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060975 | Lennon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Vanda A. Lennon (Rochester, Minnesota); Sean J. Pittock (Rochester, Minnesota); Shannon Hinson (Rochester, Minnesota) |
| ABSTRACT | The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases. |
| FILED | Friday, May 05, 2023 |
| APPL NO | 18/143917 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) A61K 39/395 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) Original (OR) Class G01N 2333/705 (20130101) G01N 2800/52 (20130101) G01N 2800/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060990 | Coskun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ahmet F. Coskun (Atlanta, Georgia); Shuangyi Cai (Atlanta, Georgia); Thomas Hu (Atlanta, Georgia) |
| ABSTRACT | Disclosed herein are methods of detecting multiple protein interactions within a cell or tissue sample. This can be done by multiplexed imaging. Also disclosed are systems and kits for carrying this out. |
| FILED | Friday, August 18, 2023 |
| APPL NO | 18/452178 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) C12Q 1/6804 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 33/542 (20130101) G01N 33/5308 (20130101) G01N 33/6872 (20130101) Original (OR) Class G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061002 | Dailey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Salus Discovery, LLC (Madison, Wisconsin); Flambeau Diagnostics, LLC (Monona, Wisconsin); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter James Dailey (Clayton, California); Richard McGregor Thayer (Meridian, Idaho); Laura Terese Mazzola (San Francisco, California); Paul Scott Eastman (Danville, California); Michael S. Urdea (Alamo, California); Jesse Charles Darley (Madison, Wisconsin); Ryan Lee Anton (Madison, Wisconsin); Katherine Gail Mason (Plain City, Ohio); Sara Willoughby Berg-Love (Loudonville, New York); Justin Daniel Chan (Middleton, Wisconsin); Russell Prince (Middleton, Wisconsin); Douglas Paul Barnes (San Francisco, California); Evan Alex Bunke (Madison, Wisconsin); Jacob Emory Schepp (Marshall, Wisconsin); Douglas E. Seals (Fitchburg, Wisconsin); Alexandra A. Surasky-Ysasi (Madison, Wisconsin); Angie Purvis (Evergreen, Colorado); Christina Newman (Madison, Wisconsin); Dawn Dudley (Madison, Wisconsin); David O'Connor (Madison, Wisconsin); Thomas Friedrich (Madison, Wisconsin); Steven Carbone (Woburn, Massachusetts); Madalyn Gill (Madison, Wisconsin); Brianna Mullins (Deforest, Wisconsin); Jay Warrick (Madison, Wisconsin); Patrick McMinn (Madison, Wisconsin); Dave Beebe (Monona, Wisconsin); Ryan Shogren (Madison, Wisconsin); Mitch Geiger (Madison, Wisconsin); Franklin Zhong (Madison, Wisconsin); Duane S. Juang (Madison, Wisconsin); Terry D. Juang (Madison, Wisconsin) |
| ABSTRACT | Provided herein are mobile systems for sample processing. In some aspects, provided herein are mobile systems for sample processing and methods of use thereof for detection of pathogens in biological samples. |
| FILED | Wednesday, January 05, 2022 |
| APPL NO | 18/270438 |
| CURRENT CPC | Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/01 (20130101) B03C 1/288 (20130101) B03C 2201/18 (20130101) B03C 2201/26 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/0098 (20130101) Original (OR) Class G01N 35/0099 (20130101) G01N 35/1011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061449 | Ames et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Aaron D. Ames (Pasadena, California); Andrew W. Singletary (Pasadena, California) |
| ABSTRACT | Systems and methods for performing high-speed geofencing in accordance with various embodiments of the invention are disclosed. One embodiment includes a robotics platform including a set of one or more motors, at least one sensor, a controller comprising a set of one or more processors, and a memory containing a controller application and a backup controller application, wherein the controller application configures the set of processors to control the robotics platform by performing the steps of receiving user commands, generating commands controlling the set of one or more motors based on the received commands. The backup controller application configures the set of processors to monitor the controller and intervene as the commands received by the controller direct the robotics platform towards a boundary by performing the steps of defining a safe set identifying positions where the robotics platform is safe, defining an invariant safe set based upon a backup set, where the invariant safe set is a subset of the safe set, and the backup set is a subset of both the invariant safe set and the safe set, receiving commands controlling the set of one or more motors to track to a desired velocity, determining if the robotic platform is approaching, and upon a determination that the robotics platform is approaching a boundary of the invariant safe set, switching control of the motors from the received commands to a combination of the received commands and backup controls generated by the backup controller application. |
| FILED | Wednesday, November 08, 2023 |
| APPL NO | 18/324042 |
| CURRENT CPC | Unmanned aerial vehicles [UAV]; equipment therefor B64U 50/19 (20230101) B64U 2201/10 (20230101) Systems for Controlling or Regulating Non-electric Variables G05D 1/106 (20190501) Original (OR) Class Electric Digital Data Processing G06F 17/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062332 | Yoon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siyeop Yoon (Boston, Massachusetts); Reza Nezafat (Newton, Massachusetts) |
| ABSTRACT | A method for generating a magnetic resonance (MR) image of a subject includes receiving an MR image of the subject reconstructed from undersampled MR data of the subject and providing the low resolution MR image of the subject to an image sharpness neural network. The image sharpness neural network can be implemented without an upsampling layer. The image sharpness neural network may be trained using a set of loss functions including an L1 Fast Fourier Transform (FFT) loss function. The method may further include generating an enhanced resolution MR image of the subject with increased sharpness based on the MR image of the subject using the image sharpness neural network. |
| FILED | Friday, August 12, 2022 |
| APPL NO | 17/887096 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4818 (20130101) Image Data Processing or Generation, in General G06T 3/4046 (20130101) Original (OR) Class G06T 5/003 (20130101) G06T 5/10 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062366 | Woodard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pamela Woodard (St. Louis, Missouri); Ran Li (St. Louis, Missouri); Abhinav Kumar Jha (St. Louis, Missouri); Jie Zheng (St. Louis, Missouri) |
| ABSTRACT | Disclosed are systems, apparatuses, processes, and computer-readable media to provide haptic feedback in electronic devices based on contextual awareness. A method of processing image data includes receiving at least one image of a patient; providing the image of the patient to a trained model for segmenting the image; and processing the image based on a multi-stage trained model to segment the image into a plurality of segmented images that are separated based on plaque components. |
| FILED | Monday, August 21, 2023 |
| APPL NO | 18/236034 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062370 | Halder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sourav Halder (Evanston, Illinois); Ethan M. Johnson (Evanston, Illinois); Jun Yamasaki (Evanston, Illinois); Peter J. Kahrilas (Evanston, Illinois); Michael Markl (Evanston, Illinois); John Erik Pandolfino (Evanston, Illinois); Neelesh A. Patankar (Evanston, Illinois) |
| ABSTRACT | Esophageal bolus transport and esophageal mechanics are quantified from medical imaging data, such as dynamic magnetic resonance imaging (“MRI”) data, computed tomography (“CT”) data, or the like. A machine learning model is used to process geometric or other spatiotemporal parameters of a bolus imaged with medical imaging in order to estimate quantitative parameters of the bolus and/or esophagus, such as cross-sectional area, fluid velocity, and fluid pressure. From these values, other parameters can be computed, such as esophageal stiffness and active relaxation. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/446925 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/30004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062523 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Siemens Medical Solutions USA, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gengyan Zhao (Plainsboro, New Jersey); Youngjin Yoo (Princeton, New Jersey); Thomas Re (New York, New York); Eli Gibson (Plainsboro, New Jersey); Dorin Comaniciu (Princeton, New Jersey) |
| ABSTRACT | Systems and methods for generating synthesized medical images of a tumor are provided. A 3D mask of an anatomical structure generated from a 3D medical image and a 3D image of a plurality of concentric spheres are received. A 3D mask of a tumor is generated based on the 3D mask of the anatomical structure and the 3D image of the plurality of concentric spheres using a first 3D generator network. A 3D intensity map of the tumor is generated based on the 3D mask of the tumor and the 3D image of the plurality of concentric spheres using a second 3D generator network. A 3D synthesized medical image of the tumor is generated based on one or more 2D slices of the 3D intensity map of the tumor and one or more 2D slices of the 3D medical image using a 2D generator network. The 3D synthesized medical image of the tumor is output. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/161186 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/50 (20130101) G06T 7/0012 (20130101) G06T 2200/04 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20212 (20130101) G06T 2207/30016 (20130101) G06T 2207/30096 (20130101) Image or Video Recognition or Understanding G06V 10/764 (20220101) G06V 10/774 (20220101) Original (OR) Class G06V 2201/03 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062564 | CHENNUBHOTLA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| INVENTOR(S) | SRINIVAS C. CHENNUBHOTLA (PITTSBURGH, Pennsylvania); DOUGLASS L. TAYLOR (PITTSBURGH, Pennsylvania); SHIKHAR UTTAM FNU (PITTSBURGH, Pennsylvania) |
| ABSTRACT | A method of predicting cancer recurrence risk for an individual includes receiving patient spatial multi-parameter cellular and sub-cellular imaging data for a tumor of the individual, and analyzing the patient spatial multi-parameter cellular and sub-cellular imaging data using a prognostic model for predicting cancer recurrence risk to determine a predicted cancer recurrence risk for the individual, wherein the joint prognostic model is based on spatial correlation statistics among features derived for a plurality of intra-tumor spatial domains from spatial multi-parameter cellular and sub-cellular imaging data obtained from a plurality of cancer patients. |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/493740 |
| CURRENT CPC | Electric Digital Data Processing G06F 18/211 (20230101) G06F 18/217 (20230101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image or Video Recognition or Understanding G06V 10/26 (20220101) G06V 10/50 (20220101) G06V 10/771 (20220101) G06V 10/776 (20220101) G06V 20/698 (20220101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240057701 | NEWMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Dava J. NEWMAN (Cambridge, Massachusetts); Skylar TIBBITS (Nahant, Massachusetts); Hugh M. HERR (Concord, New Hampshire); Svetlana BORISKINA (Winchester, Massachusetts); Lavender TESSMER (Cambridge, Massachusetts); Volodymyr KOROLOVYCH (Boston, Massachusetts); Atharva SAHASRABUDHE (Cambridge, Massachusetts); Ganit GOLDSTEIN (Cambridge, Massachusetts); Jesus Guillermo HERRERA ARCOS (Somerville, Massachusetts); Rachel BELLISLE (Cambridge, Massachusetts); Cody PAIGE (Medford, Massachusetts); Christopher SHALLAL (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed herein is a wearable article, comprising a fabric. In some embodiments, the fabric comprises an inner material layer which forms an inner surface of the wearable article, an outer material layer which forms an outer surface of the wearable article; and one or more intermediate material layers disposed between the inner and outer material layers. In some embodiments, the inner, outer, and one or more intermediate material layers are knitted together to provide a combination of two or more of: two or more compression zones; two or more mobility zones; two or more materials; or one or more electronic components. |
| FILED | Monday, August 21, 2023 |
| APPL NO | 18/452752 |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/1236 (20130101) A41D 27/10 (20130101) Original (OR) Class A41D 2500/10 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/026 (20130101) B32B 5/26 (20130101) B32B 5/073 (20210501) B32B 7/02 (20130101) B32B 7/05 (20190101) B32B 2250/20 (20130101) B32B 2262/0253 (20130101) B32B 2307/51 (20130101) B32B 2307/7376 (20230501) B32B 2437/00 (20130101) B32B 2571/00 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240057874 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Nathaniel Braman (Bethel Park, Pennsylvania) |
| ABSTRACT | The present disclosure relates to a method. The method may be performed by accessing data derived from one or more routine clinical medical imaging scans including a lesion in which the lesion and associated vasculature are segmented in a three-dimensional segmentation. At least two features are extracted from the three-dimensional segmentation of the associated vasculature. The at least two features include at least one feature indicative of a morphology of the associated vasculature or a portion thereof, and at least one feature indicative of a function of the associated vasculature or a portion thereof. The at least two features, and/or one or more statistics of the at least two features, are provided to a machine learning model trained to make a prediction concerning the lesion. The prediction concerning the lesion is received from the machine learning model. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/495821 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/004 (20130101) A61B 5/08 (20130101) A61B 5/0035 (20130101) A61B 5/02007 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/12 (20170101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20036 (20130101) G06T 2207/20081 (20130101) G06T 2207/30061 (20130101) G06T 2207/30068 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240057926 | Liew et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTHEN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHEN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Sook-Lei Liew (Los Anges, California); Octavio Marin-Pardo (Los Angeles, California); Coralie Phanord (Los Angeles, California) |
| ABSTRACT | A plurality of sensors detect neural activity and/or muscle activity of a person. A display renders an image with an avatar that represents the person. A processor moves a portion of the avatar in response to calculations performed on signals corresponding to the neural activity and the muscle activity. The avatar may be caused to move in a manner corresponding to an expected muscle movement of the person. However, due to illness or disease, the person may be unable to fully execute the expected muscle movement. By watching the avatar move in response to efforts to execute an expected muscle movement, the person may train his or her body to more fully execute desired muscle movements, such as through neurofeedback for rehabilitation. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 18/269656 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/256 (20210101) A61B 5/291 (20210101) A61B 5/296 (20210101) A61B 5/372 (20210101) A61B 5/375 (20210101) Original (OR) Class A61B 5/397 (20210101) A61B 5/744 (20130101) A61B 5/7267 (20130101) A61B 5/7455 (20130101) A61B 2560/0431 (20130101) A61B 2560/0443 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058009 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Timothy K. Williams (Davis, California); Lucas Paul Neff (Davis, California) |
| ABSTRACT | Endovascular variable aortic control catheters (EVACC) are provided that are adapted to augment upstream blood pressure and regulate downstream blood flow for patients in shock. The EVACC devices provide improved treatment for truncal wounds, which may be used for example on a battlefield, thereby increasing survivability of injured soldiers. The devices are a catheter-based system having a proximal hand piece for controlled deployment of the device through a delivery sheath. A collapsible, wire framework supports an expandable and collapsible occlusion barrier. The wire basket and occlusion barrier expand to fit within the lumen of the aorta. Various movable elements are used to adjust an adjustable passageway to regulate controlled anterograde blood flow. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/495057 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12109 (20130101) Original (OR) Class A61B 17/12122 (20130101) A61B 17/12131 (20130101) A61B 17/12168 (20130101) A61B 17/12172 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 60/13 (20210101) A61M 60/50 (20210101) A61M 60/139 (20210101) A61M 60/295 (20210101) A61M 60/833 (20210101) A61M 60/843 (20210101) A61M 2205/3334 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058027 | Faleris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Axogen Corporation (Alachua, Florida) |
| ASSIGNEE(S) | Axogen Corporation (Alachua, Florida) |
| INVENTOR(S) | Jennifer Faleris (Alachua, Florida); Anne Engemann (Alachua, Florida); Curt Deister (Alachua, Florida) |
| ABSTRACT | A capture-tool for manipulation of tissue utilizes vacuum to hold the tissue in place. An extension attached to a vacuum source at one end and a vacuum arm at another end creates a vacuum force through the extension and vacuum arm. The vacuum arm has a support surface with ports therein at which low pressure areas are formed by the vacuum force. The low pressure areas draw tissue against the supporting surface to hold it in place, as long as the vacuum force is active. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/496100 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/30 (20130101) Original (OR) Class A61B 17/1128 (20130101) A61B 2017/308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058584 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government Of The United States, As Represented By The Secretary Of The Air Force (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The Government Of The United States, As Represented By The Secretary Of The Air Force (Fort Detrick, Maryland) |
| INVENTOR(S) | Timothy K. Williams (Winston-Salem, North Carolina); Lucas Paul Neff (Winton-Salem, North Carolina); James B. Sampson (Davis, California) |
| ABSTRACT | A vascular access disassembling needle assembly is provided that enables rapid insertion of a guide wire into the needle and subsequent rapid removal of the access needle off the guide wire by facile disassembly of the needle. The disassembling needle assembly includes a needle portion wherein the needle breaks apart by splitting along at least one seam that extends from the proximal to the distal end to allow removal of the guide wire. Various mechanical features are described that can facilitate the separation of the needle body along at least one seam. Once one or more seams are separated, the needle body may be removed from the guide wire without the need to withdraw the needle along the length of the guide wire, which permits preloading of expanders and other medical devices onto the guidewire. |
| FILED | Monday, October 30, 2023 |
| APPL NO | 18/497661 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/34 (20130101) A61B 17/3403 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/065 (20130101) Original (OR) Class A61M 25/0169 (20130101) A61M 25/0668 (20130101) A61M 25/09041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058765 | Pozzo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Lilo D. Pozzo (Seattle, Washington); Anthony William Moretti (Seattle, Washington); Gregory M. Newbloom (Seattle, Washington); Aaron West (Seattle, Washington); Eden Rivers (Seattle, Washington) |
| ABSTRACT | Disclosed herein are ceramic selective membranes and methods of forming the ceramic selective membranes by forming a selective silica ceramic on a porous membrane substrate. |
| FILED | Thursday, February 16, 2023 |
| APPL NO | 18/170340 |
| CURRENT CPC | Separation B01D 39/2068 (20130101) B01D 61/025 (20130101) B01D 67/0048 (20130101) Original (OR) Class B01D 67/0076 (20130101) B01D 67/0079 (20130101) B01D 67/0088 (20130101) B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 69/105 (20130101) B01D 69/148 (20130101) B01D 71/02 (20130101) B01D 71/26 (20130101) B01D 71/027 (20130101) B01D 71/28 (20130101) B01D 71/76 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/106 (20130101) H01M 8/188 (20130101) H01M 8/0236 (20130101) H01M 8/0239 (20130101) H01M 8/0245 (20130101) H01M 8/1016 (20130101) H01M 8/1053 (20130101) H01M 8/1062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059404 | Whiteford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LORD Corporation (Cary, North Carolina) |
| ASSIGNEE(S) | LORD Corporation (Cleveland, Ohio) |
| INVENTOR(S) | Gerald P Whiteford (Waterford, Pennsylvania); Sean A Coots (Durham, North Carolina); Douglas A Swanson (Cary, North Carolina); John L Sheppard (New Hill, North Carolina); Michael D Janowski (Clayton, North Carolina); Douglas C Leicht (Cranesvile, Pennsylvania) |
| ABSTRACT | The present disclosure provides an improved circular force generator having a housing configured to reduce vibrational forces transmitted to an aircraft structure. Additionally, the disclosed configuration provide the necessary safety redundancies required by the aviation industry. The circular force generator includes mounting point around the exterior of the CFG housing and a central mounting point thereby providing redundant mounting points. |
| FILED | Wednesday, March 01, 2023 |
| APPL NO | 18/116051 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/001 (20130101) Original (OR) Class B64C 2027/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059572 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Qiucheng Li (Evanston, Illinois) |
| ABSTRACT | One aspect of this invention relates to synthesis of borophane polymorphs by hydrogenating borophene with atomic hydrogen in ultrahigh vacuum, including growing borophene on a substrate in an ultrahigh vacuum chamber; and performing hydrogenation of the borophene in situ to obtain borophane having a diverse set of borophane polymorphs. The borophane polymorphs are metallic with modified local work functions that can be reversibly returned to pristine borophene via thermal desorption of hydrogen. Hydrogenation also provides chemical passivation such that the borophane polymorphs have negligible oxidation for multiple days following ambient exposure. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 18/270903 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/026 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/20 (20130101) C01P 2006/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060050 | Mochel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan P. Mochel (Morlaas, France); Karin Allenspach Jorn (Statham, Georgia); Vojtech Gabriel (Portland, Maine); Christopher Zdyrski (Winterville, Georgia) |
| ABSTRACT | The present invention relates to hepatic organoids and uses thereof. The compositions include models for the study of developmental biology of the liver and other epithelial tissues, drug discovery and toxicity screening, infectious disease biology of various infectious agents, and personalized medicines. Methods for seeding canine intestinal organoids, maintaining an organoid monolayer, and monitoring monolayer integrity are provided. Methods and systems for culturing, freezing, and recovering the frozen organoid cells are also provided. The hepatic organoids may also be used to treat a subject in need, or for identifying a preferred therapeutic agent. |
| FILED | Monday, September 18, 2023 |
| APPL NO | 18/469214 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0671 (20130101) Original (OR) Class C12N 2501/12 (20130101) C12N 2501/39 (20130101) C12N 2501/42 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2503/04 (20130101) C12N 2506/14 (20130101) C12N 2510/00 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060080 | Medford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (FORT COLLINS, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | June Medford (Fort Collins, Colorado); Kevin Morey (Fort Collins, Colorado); Tessema Kassaw (Fort Collins, Colorado); Mauricio Antunes (Fort Collins, Colorado) |
| ABSTRACT | The present disclosure provides compositions and methods for generating plants that can grow in saline conditions, or remove a salt or other impurity from water, for example plants that can remove sodium chloride from salt or sea water, and plants that can produce purified water from salt or sea water. |
| FILED | Friday, May 19, 2023 |
| APPL NO | 18/320582 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/327 (20130101) C02F 2103/08 (20130101) Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8259 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060105 | WANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zheng WANG (Burke, Virginia); Aaron SMITH (Alexandria, Virginia); Tanya TSCHIRHART (Odenton, Maryland); Jaimee COMPTON (Washington, District of Columbia) |
| ABSTRACT | Improved yields of melanin are obtained by incubating, in an optimized media with a disodium tyrosine substrate, a culture of Vibrio natriegens expressing a heterologous tyrosinase gene at a temperature of about 30° C. |
| FILED | Thursday, August 03, 2023 |
| APPL NO | 18/229933 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/0071 (20130101) C12N 15/74 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/182 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/63 (20210501) Enzymes C12Y 114/18001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060118 | Walper et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott A. Walper (Springfield, Virginia); Igor L. Medintz (Springfield, Virginia); Divita Mathur (Fairfax, Virginia); Sebastian A. Diaz (Silver Spring, Maryland); Meghna Thakur (Arlington, Virginia); Kimihiro Susumu (Washington, District of Columbia); Michael H. Stewart (Washington, District of Columbia) |
| ABSTRACT | A FRET based reporter system utilizing the fluorescent semiconductor quantum dots (QDs) and restriction enzymes expressed in cell-free system has the potential to detect multiple analytes in single reaction. |
| FILED | Tuesday, May 30, 2023 |
| APPL NO | 18/203189 |
| CURRENT CPC | Peptides C07K 7/08 (20130101) C07K 2319/21 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060125 | Ceze et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Luis H. Ceze (Seattle, Washington); Kathryn J. Doroschak (Seattle, Washington); Jeffrey M. Nivala (Seattle, Washington) |
| ABSTRACT | In some embodiments, a molecular tagging system that uses synthetic DNA-based tags is provided. In some embodiments, a kit for tagging objects with molecular tags is provided that comprises a plurality of molbit reservoirs. Each molbit reservoir is associated with a molbit and includes nucleic acid molecules that represent the molbit. In some embodiments, a method is provided wherein a digital tag value is determined, the digital tag value is converted to a molbit tag value, nucleic acid molecules associated with each molbit value indicated as present in the molbit tag value are combined, and the combined nucleic acid molecules are applied to an object to tag the object. In some embodiments, a system is provided that includes a computing system configured to receive raw nanopore signals from a sequencing device, to identify molbits based on the signals, and to determine a digital tag based on the identified molbits. |
| FILED | Wednesday, May 10, 2023 |
| APPL NO | 18/315022 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060837 | Adelson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Edward Adelson (Winchester, Massachusetts) |
| ABSTRACT | A retrographic sensor includes a transparent structure, a transparent elastomeric pad, and an at least partially reflective layer. One or more excitation light sources emit light toward a side surface of the transparent structure. The side surface may include a fluorescent layer, where the light from the one or more excitation light sources excites fluorescent emissions from the fluorescent layer. The fluorescent emissions may illuminate the at least partially reflective layer. |
| FILED | Thursday, October 14, 2021 |
| APPL NO | 18/267032 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 19/021 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/241 (20130101) Original (OR) Class G01L 5/166 (20130101) G01L 5/226 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060962 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Bo Sun (Corvallis, Oregon); Pedram Esfahani (Corvallis, Oregon) |
| ABSTRACT | Disclosed herein are embodiments of cell culture assays for simultaneous study of chemical and mechanical cues. Also disclosed herein are extracellular matrices for use with the cell culture assays. In some examples, the extracellular matrices can have a textured fibrous structure. Also disclosed herein are embodiments of a modular apparatus for forming the cell culture assays and the extracellular matrices used with the cell culture assays. Methods for using the cell culture assays are also disclosed herein. |
| FILED | Thursday, August 10, 2023 |
| APPL NO | 18/448091 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/42 (20130101) C12M 23/48 (20130101) C12M 25/04 (20130101) C12M 41/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 2513/00 (20130101) C12N 2533/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061112 | Ptasinski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| INVENTOR(S) | Joanna Ptasinski (San Diego, California); Melvin Pascoguin (San Diego, California) |
| ABSTRACT | The present invention relates to a quantum radar system for using entangled photons to detect and range objects. According to an illustrative embodiment of the present disclosure, an entangled photon source generates at least one group of entangled photons each comprising at least one signal photon and an idler photon. The entangled photon source directs the at least one signal photon toward an object of interest and the idler photon towards a slow light section comprising a slow light material. The idler photon passes through the slow light section and continues to a photon detector. The at least one entangled photon reflects off of the objection of interest and continues to the detector. |
| FILED | Monday, August 22, 2022 |
| APPL NO | 17/892572 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4814 (20130101) G01S 7/4816 (20130101) G01S 17/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061192 | CHIU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chia-Pin CHIU (Tempe, Arizona); Finian ROGERS (Newbridge, Iran); Tim Tri HOANG (San Jose, California); Kaveh HOSSEINI (Livermore, California); Omkar KARHADE (Chandler, Arizona) |
| ABSTRACT | Embodiments disclosed herein include electronic packages and methods of forming electronic packages. In an embodiment, the electronic package comprises a package substrate, a die coupled to the package substrate, a photonics integrated circuit (PIC) coupled to the die, and a fiber array unit (FAU) optically coupled to the PIC. In an embodiment, the FAU has a base with a first width and a protrusion with a second width that is smaller than the first width. |
| FILED | Tuesday, August 16, 2022 |
| APPL NO | 17/889233 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/425 (20130101) Original (OR) Class G02B 6/4243 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061219 | DEVLIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert C. DEVLIN (Cambridge, Massachusetts); Mohammadreza KHORASANINEJAD (Cambridge, Massachusetts); Federico CAPASSO (Cambridge, Massachusetts); Hongkun PARK (Cambridge, Massachusetts); Alexander HIGH (Cambridge, Massachusetts) |
| ABSTRACT | A method of fabricating a visible spectrum optical component includes: providing a substrate; forming a resist layer over a surface of the substrate; patterning the resist layer to form a patterned resist layer defining openings exposing portions of the surface of the substrate; performing deposition to form a dielectric film over the patterned resist layer and over the exposed portions of the surface of the substrate, wherein a top surface of the dielectric film is above a top surface of the patterned resist layer; removing a top portion of the dielectric film to expose the top surface of the patterned resist layer and top surfaces of dielectric units within the openings of the patterned resist layer; and removing the patterned resist layer to retain the dielectric units over the substrate. |
| FILED | Friday, November 03, 2023 |
| APPL NO | 18/501954 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/042 (20130101) C23C 16/56 (20130101) C23C 16/45525 (20130101) C23C 16/45555 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 1/02 (20130101) G02B 1/005 (20130101) G02B 13/14 (20130101) Original (OR) Class Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) G03F 7/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061226 | Boppart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen A. Boppart (Champaign, Illinois); Mantas Zurauskas (Urbana, Illinois) |
| ABSTRACT | Systems and methods for phase-sensitive optical coherence tomography (“OCT”) and/or optical coherence microscopy (“OCM”) include imparting multiple phase shifts to the object beam, the reference beam, or both in an interferometer. Phase shifts can be imparted to the S-polarization and/or P-polarization modes of the object and/or reference beams. As an example, phase shifts can be imparted to the reference beam in the reference arm using a waveplate or other phase shifter. A non-polarizing beamsplitter can provide additional phase shifts to light reflected by the beamsplitter. Full field OCM can be provided by imaging the phase-shifted channels using an image sensor. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 18/260987 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02091 (20130101) G01B 2290/70 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0056 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061238 | Myers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason D. Myers (Alexandria, Virginia); Jesse A. Frantz (Washington, District of Columbia); Jasbinder S. Sanghera (Ashburn, Virginia); Daniel Rhonehouse (Huntingtown, Maryland); Christopher Bardeen (Riverside, California); Colin Baker (Alexandria, Virginia); Geoffrey Chin (Oakton, Virginia); Peter Alexander Morrison (Alexandria, Virginia) |
| ABSTRACT | Systems and methods are provided for a mechanical actuator based on a fiber optic platform. A material that is configured to be activated by light is incorporated into an optical fiber that serves as both an actuator and a power delivery network. This platform is adaptable to different materials, types of motions, and length scales and allows for precise delivery of photons to the material. |
| FILED | Tuesday, August 08, 2023 |
| APPL NO | 18/366828 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/103 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061448 | Casbeer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Casbeer (Xenia, Ohio); Satyanarayana Manyam (Beavercreek, Ohio) |
| ABSTRACT | Methods of aerial vehicle trajectory planning are provided. The method is used where the aerial vehicle is in an area with one or more obstacles therein and the aerial vehicle has a minimum turn radius. The methods involve finding safe flight corridors, which are constructed from sequences of triangles using constrained Delaunay triangulation of the feasible space. A quadratic Bezier curve corresponding to each triangle in the flight corridor is defined. The trajectory is composed of quadratic Bezier curves that are aligned end-to-end which satisfy the vehicle motion constraints. The method described herein may also be used for path planning. |
| FILED | Saturday, July 22, 2023 |
| APPL NO | 18/225122 |
| CURRENT CPC | Unmanned aerial vehicles [UAV]; equipment therefor B64U 10/25 (20230101) B64U 2201/10 (20230101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/20 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/106 (20190501) Original (OR) Class Traffic Control Systems G08G 5/0021 (20130101) G08G 5/0034 (20130101) G08G 5/0069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061965 | Morris et al. |
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| FUNDED BY |
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| APPLICANT(S) | PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clinton Morris (San Carlos, California); Amirmassoud Mirzendehdel (San Mateo, California); Morad Behandish (Mountain View, California) |
| ABSTRACT | One or more physical constraints are selected from a plurality of physical constraints for a part. The physical constraints are for use by a physics solver and define a physical performance of the part. One or more connectivity constraints are defined for use by the physics solver. The connectivity constraints enforce connectivity to or from at least one region over a complement space of the part. The connectivity constraints include locally differentiable violation measures that are modeled after at least one of the physical constraints. A topology of the part is optimized in the physics solver by enforcing the physical constraints and the connectivity constraints while satisfying a primary objective function that optimizes the physical performance of the part. A computer-aided design of the part is produced based on the optimized topology. |
| FILED | Wednesday, December 21, 2022 |
| APPL NO | 18/086048 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/10 (20200101) Original (OR) Class G06F 30/23 (20200101) G06F 2111/04 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062015 | Scott |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Alicia L Scott (El Segundo, California) |
| ABSTRACT | The present invention relates to methods and systems that use natural language processing (NLP) to read data from a file and analyze the data based on user defined parameters. According to an illustrative embodiment of the present disclosure, a system can process and analyze a data file by finding trending themes across data entries. According to a further illustrative embodiment of the present disclosure, the system can search for reoccurring or repeated words/phrases based on Ngrams (i.e., n-grams). The system can be adapted to search for Ngrams of varying length depending on the information sought and can sort the results by Ngram length. |
| FILED | Wednesday, July 26, 2023 |
| APPL NO | 18/226297 |
| CURRENT CPC | Electric Digital Data Processing G06F 40/30 (20200101) Original (OR) Class G06F 40/226 (20200101) G06F 40/284 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062042 | Nadamuni Raghavan et al. |
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| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aswin Nadamuni Raghavan (Princeton, New Jersey); Saurabh Farkya (Princeton, New Jersey); Jesse Albert Hostetler (Boulder, Colorado); Avraham Joshua Ziskind (Cherry Hill, New Jersey); Michael Piacentino (Robbinsville, New Jersey); Ajay Divakaran (Monmouth Junction, New Jersey); Zhengyu Chen (Redwood City, California) |
| ABSTRACT | In general, the disclosure describes techniques for implementing an MI-based attack detector. In an example, a method includes training a neural network using training data, applying stochastic quantization to one or more layers of the neural network, generating, using the trained neural network, an ensemble of neural networks having a plurality of quantized members, wherein at least one of weights or activations of each of the plurality of quantized members have different bit precision, and combining predictions of the plurality of quantized members of the ensemble to detect one or more adversarial attacks and/or determine performance of the ensemble of neural networks. |
| FILED | Thursday, August 17, 2023 |
| APPL NO | 18/451692 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/566 (20130101) G06F 2221/033 (20130101) Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) Original (OR) Class G06N 3/098 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240063340 | Keller et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Stacia Keller (Santa Barbara, California); Umesh K. Mishra (Montecito, California); Shubhra Pasayat (Goleta, California); Chirag Gupta (Goleta, California) |
| ABSTRACT | The present disclosure describes porous GaN layers and/or compliant substrates used to enable relaxation of previously strained top layers and the deposition of relaxed or partially relaxed on top. Relaxed In GaN layers are fabricated without generation of crystal defects, which can serve as base layers for high performance long wavelength light emitting devices (LEDs, lasers) solar cells, or strain engineered transistors. Similarly, relaxed AlGaN layers can serve as base layers for high performance short wavelength UV light emitting devices (LEDs, lasers) solar cells, or wide bandgap transistors. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/642057 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/0753 (20130101) H01L 33/12 (20130101) H01L 33/16 (20130101) H01L 33/20 (20130101) H01L 33/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240063555 | SHIEH |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| INVENTOR(S) | Jia-Chi Samuel SHIEH (San Diego, California) |
| ABSTRACT | A method for radiating a co-located antenna including radiating the co-located antenna using a dual mode, where the co-located antenna has an inter-element spacing of about 1λ and the dual mode includes a TM11 mode and a TM21 mode. The TM11 mode is radiated to generate a TM11 far field pattern, where the TM11 mode has a broadside pattern characterized with a beam peak at broadside and the TM11 mode produces grating lobes in addition to the beam peak at broadside. The TM21 mode is radiated to generate a TM21 far field pattern orthogonal to the TM11 far field pattern, thereby causing the TM21 mode to produce a null at broadside to suppress the grating lobes produced by the TM11 mode. |
| FILED | Tuesday, August 08, 2023 |
| APPL NO | 18/366856 |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/16 (20130101) Antennas, i.e Radio Aerials H01Q 9/0478 (20130101) H01Q 21/10 (20130101) H01Q 21/293 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240063556 | CHIEH |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| INVENTOR(S) | Jia-Chi Samuel CHIEH (San Diego, California) |
| ABSTRACT | A method for radiating a co-located antenna including radiating the co-located antenna using a dual mode, where the co-located antenna has an inter-element spacing of about 1λ and the dual mode includes a TM11 mode and a TM21 mode. The TM11 mode is radiated to generate a TM11 far field pattern, where the TM11 mode has a broadside pattern characterized with a beam peak at broadside and the TM11 mode produces grating lobes in addition to the beam peak at broadside. The TM21 mode is radiated to generate a TM21 far field pattern orthogonal to the TM11 far field pattern, thereby causing the TM21 mode to produce a null at broadside to suppress the grating lobes produced by the TM11 mode. |
| FILED | Tuesday, August 08, 2023 |
| APPL NO | 18/366863 |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/16 (20130101) Antennas, i.e Radio Aerials H01Q 9/0478 (20130101) H01Q 21/10 (20130101) H01Q 21/293 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240063806 | Higa |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian A. Higa (San Diego, California) |
| ABSTRACT | A method for improving performance of a superconducting, flux-quantizing analog to digital converter (SFADC), comprising the following steps. The first step involves providing a known digitally-modulated signal as an input to the SFADC. Another step provides for generating an output with the SFADC based on the known digitally-modulated signal. Another step provides for comparing the characteristics of the output with ideal characteristics to identify an individual rapid single flux quantum (RSFQ) element of the SFADC that is contributing one or more of noise and error to the output. Another step provides for altering one or more of a bias, a delay, and a temperature of the individual RSFQ element to reduce one or more of the noise and the error. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/890585 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/1014 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240063866 | SCHÖNBROD et al. |
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| FUNDED BY |
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| APPLICANT(S) | JuliaHub, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sören SCHÖNBROD (Aachen, Germany); Elliot SABA (Seattle, Washington) |
| ABSTRACT | Disclosed herein are systems and methods for blind adaptive beamforming narrowband signals with an uncalibrated antenna array using machine learning. A machine-learning model in the spatial domain enhances the signal of interest and mitigates interfering signals. The systems and methods described herein do not require a calibrated antenna array RF chain. They are based on a neural network that learns the structure of the signal of interest and separates it from other signals in the time, frequency, and spatial domains, without the need of any additional information. |
| FILED | Thursday, August 17, 2023 |
| APPL NO | 18/451499 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Transmission H04B 7/0617 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 27/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240063960 | Tablewski et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lynne A. Tablewski (San Diego, California); John Clark Stastny (San Diego, California); Sparta Cheung (San Diego, California); Vladimir Y. Matveyev (San Diego, California); Bryan David Bagnall (Menlo Park, California) |
| ABSTRACT | A communication terminal for addressed messaging within an Automated Identification System (AIS) arrangement includes a user interface and an Aid to Navigation (AtoN) transponder. The user interface facilitates the addressed messaging, which includes one or more of: chat messaging addressed between the communication terminal and a participant terminal of the AIS arrangement, automatic position messaging addressed from the communication terminal to a monitoring terminal of the AIS arrangement, or situational report messaging addressed from the communication terminal to a situational awareness terminal of the AIS arrangement. The AtoN transponder of the communication terminal of the AIS arrangement is coupled to the user interface for transmitting and receiving that achieves the addressed messaging. For the situational report messaging, the situational awareness terminal reformats and exchanges the addressed messaging with a web-based situational awareness tool via the internet. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/894987 |
| CURRENT CPC | Secret Communication; Jamming of Communication H04K 1/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0044 (20130101) Original (OR) Class H04L 5/0055 (20130101) H04L 63/1475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240064456 | Woodley |
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| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christa M. Woodley (Vicksburg, Mississippi) |
| ABSTRACT | One embodiment is directed to a sound bar for producing engineered acoustic signals for keeping an animal away from one or more specific areas. The sound bar includes: a weldment having a weldment top, a weldment bottom, a front weldment side, and a rear weldment side; a plurality of speakers disposed inside the weldment and spaced from each other; at least one acoustic doppler current profilers (ADCP) disposed inside the weldment; at least one hydrophone disposed inside the weldment; and a mounting mechanism configured to be attached to a discharge lateral, the mounting mechanism including a plurality of bottom supports spaced from each other to support the weldment bottom at a plurality of locations and position the weldment top below a top surface of the discharge lateral and position the rear weldment side adjacent a front side of the discharge lateral. |
| FILED | Wednesday, March 29, 2023 |
| APPL NO | 18/126415 |
| CURRENT CPC | Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/025 (20130101) H04R 1/44 (20130101) H04R 1/227 (20130101) Original (OR) Class H04R 1/288 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20240058454 | Ahmad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PARTICELLA, INC. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mubhij Ahmad (Walnut Creek, California); Timothy Day (Oakland, California); Ismail Hafez (Concord, California); John Merritt (San Mateo, California) |
| ABSTRACT | Provided are delivery vehicles, and methods of making and using same for reaching epithelial cells, such as cells within mucus-containing environments, and delivery vehicles with improved stability in harsh environments, including the gastrointestinal tract. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 18/267206 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/10 (20130101) A61K 47/28 (20130101) A61K 47/64 (20170801) A61K 47/543 (20170801) A61K 47/544 (20170801) Original (OR) Class A61K 47/6929 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058767 | Osuji et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chinedum Osuji (Gladwyne, Pennsylvania); Yizhou Zhang (Philadelphia, Pennsylvania); Xunda Feng (New Haven, Connecticut); Lucas Sixdenier (New Haven, Connecticut) |
| ABSTRACT | Disclosed herein is a polymer membrane, film or coating comprising cylindrical polymer fibers at least partially ordered as hexagonal packed cylinders within the film, aligned parallel to the film surface, and present as an H1 mesophase; wherein the cylinders are crosslinked internally within the cylinders; and wherein the cylinders are spatially arranged to provide channels between the cylinders for fluid flow through the membrane, film or coating. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 18/040484 |
| CURRENT CPC | Separation B01D 61/08 (20130101) B01D 69/125 (20130101) Original (OR) Class B01D 2323/30 (20130101) B01D 2323/64 (20220801) B01D 2323/216 (20220801) B01D 2325/04 (20130101) B01D 2325/02832 (20220801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059010 | Torabi et al. |
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| FUNDED BY |
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| APPLICANT(S) | 3DEO, Inc. (Torrance, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Payman Torabi (Los Angeles, California); Matthew Petros (Tarzana, California) |
| ABSTRACT | The present disclosure provides systems and methods for the formation of three-dimensional objects. A method for forming a three-dimensional object may comprise alternately and sequentially applying a stream comprising a binding substance to an area of a layer of powder material in a powder bed, and generating at least one perimeter of the three-dimensional object in the area. The stream may be applied in accordance with a model design of the three-dimensional object. The at least one perimeter may generated in accordance with the model design. |
| FILED | Friday, April 28, 2023 |
| APPL NO | 18/309121 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/24 (20130101) B22F 10/00 (20210101) B22F 10/14 (20210101) B22F 10/50 (20210101) B22F 10/66 (20210101) B22F 12/41 (20210101) B22F 2003/247 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/00 (20141201) B33Y 40/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059559 | HU et al. |
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| FUNDED BY |
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| APPLICANT(S) | West Virginia University Board of Governors on Behalf of West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianli HU (Morgantown, West Virginia); Brandon ROBINSON (Morgantown, West Virginia) |
| ABSTRACT | In one aspect, disclosed herein are devices comprising a disclosed hybrid microwave-thermal chemical reactor device. Also disclosed herein are methods of preparing hydrogen and a crystalline carbon material, such as a carbon nanotube, from methane using a hybrid heating comprising heating with both a thermal fluid and microwave irradiation of a catalyst. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823290 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 6/008 (20130101) B01J 21/185 (20130101) B01J 23/892 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/26 (20130101) Original (OR) Class C01B 32/05 (20170801) C01B 2203/0277 (20130101) C01B 2203/0855 (20130101) C01B 2203/1064 (20130101) C01B 2203/1082 (20130101) C01B 2203/1241 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/647 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059572 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Qiucheng Li (Evanston, Illinois) |
| ABSTRACT | One aspect of this invention relates to synthesis of borophane polymorphs by hydrogenating borophene with atomic hydrogen in ultrahigh vacuum, including growing borophene on a substrate in an ultrahigh vacuum chamber; and performing hydrogenation of the borophene in situ to obtain borophane having a diverse set of borophane polymorphs. The borophane polymorphs are metallic with modified local work functions that can be reversibly returned to pristine borophene via thermal desorption of hydrogen. Hydrogenation also provides chemical passivation such that the borophane polymorphs have negligible oxidation for multiple days following ambient exposure. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 18/270903 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 35/026 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/20 (20130101) C01P 2006/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059607 | Sant et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Los Angeles, California); Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gaurav Sant (Los Angeles, California); Laurent G. Pilon (Los Angeles, California); Bu Wang (Los Angeles, California); Narayanan Neithalath (Chandler, Arizona); Zhenhua Wei (Los Angeles, California); Benjamin Young (Los Angeles, California); Gabriel D. Falzone (Los Angeles, California); Dante Simonetti (Los Angeles, California) |
| ABSTRACT | A manufacturing process of a concrete product includes: (1) extracting calcium from solids as portlandite; (2) forming a cementitious slurry including the portlandite; (3) shaping the cementitious slurry into a structural component; and (4) exposing the structural component to carbon dioxide sourced from a flue gas stream, thereby forming the concrete product. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/222238 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 7/19 (20130101) Original (OR) Class C04B 7/38 (20130101) C04B 7/46 (20130101) C04B 7/367 (20130101) C04B 9/20 (20130101) C04B 28/04 (20130101) C04B 40/0231 (20130101) C04B 2111/00129 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059609 | Burton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Marvin Burton (Glendale, Arizona); Christian Hoover (Chandler, Arizona); Elham Fini (Phoenix, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marvin Burton (Glendale, Arizona); Christian Hoover (Chandler, Arizona); Elham Fini (Phoenix, Arizona) |
| ABSTRACT | Treating plastic particles for use in concrete includes combining plastic particles with oil to yield a mixture, heating the mixture to yield a heated mixture, cooling the heated mixture to yield a cooled mixture, and removing excess oil from the cooled mixture to yield oil-treated plastic particles (e.g., oil-treated plastic particles for concrete). In one example, the oil is vegetable oil. The vegetable oil can be soybean oil, corn oil, canola oil, safflower oil, peanut oil, olive oil, grape seed oil, cocoa butter, palm oil, rice bran oil, or a combination thereof. The oil can be waste oil (e.g., waste vegetable oil, such as that recovered from restaurants). The plastic particles can be derived from post-consumer plastic, such as recycled plastic. In one example, the post-consumer plastic includes mixed plastics. A concrete composition can include rocks, sand, cement, and the oil-treated plastic particles. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/496614 |
| CURRENT CPC | Disposal of Solid Waste B09B 3/21 (20220101) B09B 3/40 (20220101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 18/30 (20130101) Original (OR) Class C04B 28/02 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/91 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059615 | Sant et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gaurav N. Sant (Los Angeles, California); Dale Prentice (Los Angeles, California); Dante Adam Simonetti (Los Angeles, California); Jenny Arabit (Los Angeles, California) |
| ABSTRACT | The present disclosure provides methods of preparing concrete products comprising carbonation of brucite-containing concrete. The present disclosure further provides brucite containing concrete mixtures that are useful in the present methods. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/217171 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 28/10 (20130101) Original (OR) Class C04B 40/0082 (20130101) C04B 40/0231 (20130101) C04B 40/0281 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059858 | Huber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George Huber (Middleton, Wisconsin); Zhuo Xu (Madison, Wisconsin); Kevin Sanchez-Rivera (Madison, Wisconsin); Ezra Bar-Ziv (Houghton, Michigan); Shreyas Kolapkar (Houghton, Michigan); Victor Ierulli (Houghton, Michigan) |
| ABSTRACT | A system to carry out solvent targeted recovery and precipitation (STRAP) to recover individual polymers from multilayer plastic films or mixed plastic wastes, comprising a down-sizing device to shred the plastic wastes into particles with a size and aspect ratio to be flowable; a feeder that conveys the plastic particles in a constant flow without bridging; a dissolution vessel to selectively dissolve an individual polymer component in a solvent; a high temperature filter to separate the dissolved polymer component from the undissolved plastics; a precipitator to precipitate the dissolved polymer component; a low temperature filter to separate the precipitated polymer component from the solvent; and a distillation unit to purify the recycled solvent. The unique design of the feeder and the dissolution vessels allows the system to run in a semi-continuous mode. |
| FILED | Monday, August 22, 2022 |
| APPL NO | 17/892573 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/24 (20130101) C08J 11/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060039 | XUE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | XUFENG XUE (Ann Arbor, Michigan); JIANPING FU (Ann Arbor, Michigan); HUAIJING TANG (Ann Arbor, Michigan) |
| ABSTRACT | The present disclosure provides devices and in vitro methods of developing three-dimensional neural tube-like tissues. In some aspects, the disclosure provides devices and methods of developing three-dimensional neural tube-like tissues comprising forebrain-like, midbrain-like, hindbrain-like, and spinal cord-like tissues. In particular, provided herein microfluidic devices and methods of using the same for generating neural tube-like tissues, such as neural-tube like tissues comprising forebrain-like, midbrain-like, hind-brain-like, and spinal cord-like tissues. In some embodiments, uses of such neural tube-like tissues for research, compound screening and analysis, disease modeling, and therapeutics are provided. |
| FILED | Thursday, November 04, 2021 |
| APPL NO | 18/035222 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) C12M 25/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 5/0618 (20130101) Original (OR) Class C12N 5/0697 (20130101) C12N 2513/00 (20130101) C12N 2535/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060050 | Mochel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan P. Mochel (Morlaas, France); Karin Allenspach Jorn (Statham, Georgia); Vojtech Gabriel (Portland, Maine); Christopher Zdyrski (Winterville, Georgia) |
| ABSTRACT | The present invention relates to hepatic organoids and uses thereof. The compositions include models for the study of developmental biology of the liver and other epithelial tissues, drug discovery and toxicity screening, infectious disease biology of various infectious agents, and personalized medicines. Methods for seeding canine intestinal organoids, maintaining an organoid monolayer, and monitoring monolayer integrity are provided. Methods and systems for culturing, freezing, and recovering the frozen organoid cells are also provided. The hepatic organoids may also be used to treat a subject in need, or for identifying a preferred therapeutic agent. |
| FILED | Monday, September 18, 2023 |
| APPL NO | 18/469214 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0671 (20130101) Original (OR) Class C12N 2501/12 (20130101) C12N 2501/39 (20130101) C12N 2501/42 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2503/04 (20130101) C12N 2506/14 (20130101) C12N 2510/00 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060091 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation Research (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, incorporation (Gainesville, Florida) |
| INVENTOR(S) | Eric Tzy-Shi Wang (Gainesville, Florida); Chase P. Kelley (Gainesville, Florida) |
| ABSTRACT | Autoregulatory systems that have been implemented to control the expression and activity of Cast 3d, including the activity of Cast 3d in vivo, thereby reducing collateral damage in cells at off-target sites (e.g., non-target messenger RNA transcripts. The autoregulatory system is in the form of a nucleic acid molecule comprising a zinc finger binding site, a promoter, and a nucleotide sequence encoding a Cast 3d fusion protein, and a transcriptional repressor domain, and wherein the Cast 3d fusion protein binds to the zinc finger binding site and represses transcription of the nucleotide sequence encoding the Cast 3d fusion protein. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 18/267144 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2750/14143 (20130101) C12N 2800/80 (20130101) C12N 2820/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060125 | Ceze et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Luis H. Ceze (Seattle, Washington); Kathryn J. Doroschak (Seattle, Washington); Jeffrey M. Nivala (Seattle, Washington) |
| ABSTRACT | In some embodiments, a molecular tagging system that uses synthetic DNA-based tags is provided. In some embodiments, a kit for tagging objects with molecular tags is provided that comprises a plurality of molbit reservoirs. Each molbit reservoir is associated with a molbit and includes nucleic acid molecules that represent the molbit. In some embodiments, a method is provided wherein a digital tag value is determined, the digital tag value is converted to a molbit tag value, nucleic acid molecules associated with each molbit value indicated as present in the molbit tag value are combined, and the combined nucleic acid molecules are applied to an object to tag the object. In some embodiments, a system is provided that includes a computing system configured to receive raw nanopore signals from a sequencing device, to identify molbits based on the signals, and to determine a digital tag based on the identified molbits. |
| FILED | Wednesday, May 10, 2023 |
| APPL NO | 18/315022 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060199 | VARDNER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Jonathan VARDNER (New York, New York); Alan WEST (Tenafly, New Jersey); Scott BANTA (Fairfield, Connecticut) |
| ABSTRACT | A copper concentrate such as chalcopyrite is contacted with an aqueous solution includes acids and a reducing agent, such as vanadium (II) ions, chromium (II) ions, or tungstozincic acid (H6ZnW12O40). The aqueous solution reduces the copper in the copper concentrate, which can then dissolve into the solution for recovery therefrom, or precipitate out of solution as copper compounds or elemental copper for recovery in as a solid phase product. The solid phase product can then be isolated, dissolved, and further electrowinned to recover a copper product from the copper concentrate. Oxidized reducing agent can be recovered in an electrochemical device with ferrous iron reactants. Hydrometallurgical routes to convert copper concentrates to copper are potentially less expensive and less polluting than current pyrometallurgical processing and an advantageous response to environmental and economic pressures for increased copper production. |
| FILED | Wednesday, December 29, 2021 |
| APPL NO | 18/270560 |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060962 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Bo Sun (Corvallis, Oregon); Pedram Esfahani (Corvallis, Oregon) |
| ABSTRACT | Disclosed herein are embodiments of cell culture assays for simultaneous study of chemical and mechanical cues. Also disclosed herein are extracellular matrices for use with the cell culture assays. In some examples, the extracellular matrices can have a textured fibrous structure. Also disclosed herein are embodiments of a modular apparatus for forming the cell culture assays and the extracellular matrices used with the cell culture assays. Methods for using the cell culture assays are also disclosed herein. |
| FILED | Thursday, August 10, 2023 |
| APPL NO | 18/448091 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/42 (20130101) C12M 23/48 (20130101) C12M 25/04 (20130101) C12M 41/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 2513/00 (20130101) C12N 2533/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240060964 — COORDINATELY-ORDERED SINGLE CELLS WITH INDIVIDUAL IDENTITIES FOR HIGH-THROUGHPUT ASSAY
| US 20240060964 | Su et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ming Su (Newton, Massachusetts); Qingxuan Li (Boston, Massachusetts); Liyuan Ma (Newton, Massachusetts); Sidi A. Bencherif (Boston, Massachusetts); Thibault Colombani (Boston, Massachusetts) |
| ABSTRACT | Disclosed is a technology for assaying individual cells, in which the identity of each individual cell in an ordered array is determined from coordinates assigned to it, and can be readout at high throughput with microscope. The method is able to test responses of millions of identical cells in multiple chemical and physical processes with superior statistics power to facilitate deep data mining. |
| FILED | Friday, November 03, 2023 |
| APPL NO | 18/501437 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 41/36 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6408 (20130101) G01N 21/6428 (20130101) G01N 27/02 (20130101) G01N 33/505 (20130101) Original (OR) Class G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061175 | Srinivasan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karthik Srinivasan (Minneapolis, Minnesota); Bethanie Joyce Hills Stadler (Shoreview, Minnesota) |
| ABSTRACT | A non-reciprocal phase shift device may include an optical waveguide (e.g., a silicon waveguide) on a substrate; and a magneto-optical cladding layer on the optical waveguide, wherein the magneto-optical cladding layer includes a plurality of segments arranged having alternating magnetization directions aligned transverse to a longitudinal direction of the optical waveguide. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/768328 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/132 (20130101) G02B 6/1225 (20130101) Original (OR) Class G02B 6/12004 (20130101) G02B 2006/12061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061316 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Gordon H.Y. Li (Pasadena, California); Midya Parto (Pasadena, California); Ryoto Sekine (Pasadena, California); James Williams (Simi Valley, California); Christian Leefmans (Pasadena, California); Alireza Marandi (Pasadena, California) |
| ABSTRACT | A device including a programmable photonic processor configured to operate on optical pulses to perform computational sequences of linear operations and nonlinear operations each based on a parametric nonlinear optical process; a memory coupled to the processor and programmable to store or accumulate the analog optical pulse amplitudes of the optical pulses; a control circuit controlling the transfer of the analog optical pulse amplitudes between the processor and the memory according to a computation schedule; and wherein information is multiplexed in time by encoding the information onto the analog optical pulse amplitudes of the optical pulses occupying time bins at a fixed repetition rate such that the optical pulses, occupying different ones of the time bins, can be made to interact using appropriate temporal delays. |
| FILED | Friday, August 11, 2023 |
| APPL NO | 18/448700 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/39 (20130101) Original (OR) Class Optical Computing Devices; G06E 3/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061375 | DeLacy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ballydel Technologies, Inc. (Wilmington, Delaware) |
| ASSIGNEE(S) | Ballydel Technologies, Inc. (Wilmington, Delaware) |
| INVENTOR(S) | Brendan G. DeLacy (Wilmington, Delaware); Mark S. Mirotznik (Wilmington, Delaware); Benjamin S. Garrett (Wilmington, Delaware) |
| ABSTRACT | A computerized system for uniquely tagging and verifying authenticity of an article comprising: an object having a surface; a computer system adapted to: receive a three-dimensional predetermined image, create a holographic interference pattern created according to the three-dimensional predetermined image and at least one physical property of the surface of the object, wherein the holographic interference pattern is applied to the object, project a three-dimensional resulting image projected on a planar surface in response to the holographic interference pattern being illuminated wherein the computer system receives the three-dimensional resulting image, creates validation information according to a comparison of the three-dimensional predetermined image and the three-dimensional resulting image. In one embodiment, the holographic interference pattern is illuminated by a beam of light that is directed to the interference pattern by a beam splitter, thus causing the three-dimensional resulting image to be projected on the planar surface. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498749 |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/0011 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061440 | Chowdhary et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Girish Chowdhary (Champaign, Illinois); Chinmay P. Soman (Urbana, Illinois); Erkan Kayacan (Champaign, Illinois); Benjamin C. Thompson (Chcago, Illinois); Zhongzhong Zhang (Urbana, Illinois); Anwesa Choudhuri (West Bengal, India) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, obtaining video data from a single monocular camera, wherein the video data comprises a plurality of frames, wherein the camera is attached to a mobile robot that is travelling along a lane defined by a row of crops, wherein the row of crops comprises a first plant stem, and wherein the plurality of frames include a depiction of the first plant stem; obtaining robot velocity data from encoder(s), wherein the encoder(s) are attached to the robot; performing foreground extraction on each of the plurality of frames of the video data, wherein the foreground extraction results in a plurality of foreground images; and determining, based upon the plurality of foreground images and based upon the robot velocity data, an estimated width of the first plant stem. Additional embodiments are disclosed. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/486909 |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0246 (20130101) Original (OR) Class Electric Digital Data Processing G06F 18/2155 (20230101) Computer Systems Based on Specific Computational Models G06N 20/10 (20190101) Image or Video Recognition or Understanding G06V 20/41 (20220101) G06V 20/188 (20220101) Wireless Communication Networks H04W 4/40 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061449 | Ames et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Aaron D. Ames (Pasadena, California); Andrew W. Singletary (Pasadena, California) |
| ABSTRACT | Systems and methods for performing high-speed geofencing in accordance with various embodiments of the invention are disclosed. One embodiment includes a robotics platform including a set of one or more motors, at least one sensor, a controller comprising a set of one or more processors, and a memory containing a controller application and a backup controller application, wherein the controller application configures the set of processors to control the robotics platform by performing the steps of receiving user commands, generating commands controlling the set of one or more motors based on the received commands. The backup controller application configures the set of processors to monitor the controller and intervene as the commands received by the controller direct the robotics platform towards a boundary by performing the steps of defining a safe set identifying positions where the robotics platform is safe, defining an invariant safe set based upon a backup set, where the invariant safe set is a subset of the safe set, and the backup set is a subset of both the invariant safe set and the safe set, receiving commands controlling the set of one or more motors to track to a desired velocity, determining if the robotic platform is approaching, and upon a determination that the robotics platform is approaching a boundary of the invariant safe set, switching control of the motors from the received commands to a combination of the received commands and backup controls generated by the backup controller application. |
| FILED | Wednesday, November 08, 2023 |
| APPL NO | 18/324042 |
| CURRENT CPC | Unmanned aerial vehicles [UAV]; equipment therefor B64U 50/19 (20230101) B64U 2201/10 (20230101) Systems for Controlling or Regulating Non-electric Variables G05D 1/106 (20190501) Original (OR) Class Electric Digital Data Processing G06F 17/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062193 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fan Zhang (New York, New York); Ethan Cecchetti (Ithaca, New York); Kyle Croman (Sudbury, Massachusetts); Ari Juels (New York, New York); Runting Shi (Ithaca, New York) |
| ABSTRACT | An apparatus in one embodiment comprises a processing platform having at least one processing device. The processing platform implements a trusted bridge configured for at least temporary coupling between one or more data sources and a smart contract program of a blockchain. The trusted bridge comprises a secure enclave component and a relay component. Data obtained from a given one of the data sources via the relay component of the trusted bridge is authenticated in the secure enclave component of the trusted bridge. Information based at least in part on the data authenticated in the secure enclave component of the trusted bridge is provided to the smart contract program of the blockchain via the relay component of the trusted bridge. The secure enclave component illustratively receives a request for authenticated data from the blockchain smart contract program via the relay component, and responds to the request via the relay component. |
| FILED | Monday, October 30, 2023 |
| APPL NO | 18/497407 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/3678 (20130101) Original (OR) Class G06Q 2220/00 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/50 (20220501) H04L 9/0825 (20130101) H04L 9/3247 (20130101) H04L 2209/56 (20130101) H04L 2209/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062370 | Halder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sourav Halder (Evanston, Illinois); Ethan M. Johnson (Evanston, Illinois); Jun Yamasaki (Evanston, Illinois); Peter J. Kahrilas (Evanston, Illinois); Michael Markl (Evanston, Illinois); John Erik Pandolfino (Evanston, Illinois); Neelesh A. Patankar (Evanston, Illinois) |
| ABSTRACT | Esophageal bolus transport and esophageal mechanics are quantified from medical imaging data, such as dynamic magnetic resonance imaging (“MRI”) data, computed tomography (“CT”) data, or the like. A machine learning model is used to process geometric or other spatiotemporal parameters of a bolus imaged with medical imaging in order to estimate quantitative parameters of the bolus and/or esophagus, such as cross-sectional area, fluid velocity, and fluid pressure. From these values, other parameters can be computed, such as esophageal stiffness and active relaxation. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/446925 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/30004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062739 | SALAHUDDIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (OAKLAND, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | SAYEEF SALAHUDDIN (Walnut Creek, California); DOMINIC E. LABANOWSKI (Berkeley, California) |
| ABSTRACT | An acoustically driven ferromagnetic resonance (ADFMR) device has a piezoelectric element comprised of piezoelectric material, first and second electrodes arranged in a vertical stack with the piezoelectric element to activate the piezoelectric element to generate an acoustic wave, a radio frequency voltage source electrically connected to the first electrode, a magnet comprised of a magnetostrictive material in the vertical stack with the first and second electrodes and the piezoelectric element to receive the acoustic wave, wherein the acoustic wave resonates at a ferromagnetic resonance of the magnetostrictive material, and a readout circuit to detect a change in the acoustic wave by detecting one of an output voltage amplitude, a change in impedance or a reflection of the acoustic wave in the magnet to measure an unknown magnetic field in which the ADFMR device resides and as experienced at the magnetostrictive element. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/496299 |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/10 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/18 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062886 | Scherrer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | QUANTIVLY INC. (Somerville, Massachusetts) |
| ASSIGNEE(S) | QUANTIVLY INC. (Somerville, Massachusetts) |
| INVENTOR(S) | Benoit Scherrer (Somerville, Massachusetts); Robert D. MacDougall (La Mesa, California); Dimitri Falco (Dexter, Michigan) |
| ABSTRACT | A computer-implemented method and system train a model of imaging examinations based on data representing a plurality of historical imaging examinations, and generate, using the model of imaging examinations and a current schedule of imaging appointments, a schedule recommendation. The schedule recommendation recommends an imaging appointment within the current schedule of imaging appointments. The current schedule of imaging appointments may be updated based on the schedule recommendation, such as by adding the recommended imaging appointment to the current schedule or by modifying an existing imaging appointment in the current schedule. The schedule recommendation may be generated in response to a request or dynamically. |
| FILED | Friday, August 18, 2023 |
| APPL NO | 18/452317 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062953 | SULLIVAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles R. SULLIVAN (West Lebanon, New Hampshire); Aaron L. F. STEIN (West Lebanon, New Hampshire); Phyo Aung KYAW (West Lebanon, New Hampshire) |
| ABSTRACT | A resonant coil with integrated capacitance includes at least one separation dielectric layer and a plurality of conductor layers stacked in an alternating manner. Each of the plurality of conductor layers includes a first conductor sublayer and second conductor sublayer having common orientation and a sublayer dielectric layer separating the first and second conductor sublayers. Adjacent conductor layers of the plurality of conductor layers have different orientations. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/380063 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/24 (20130101) H01F 27/40 (20130101) Original (OR) Class H01F 27/2804 (20130101) H01F 2027/2809 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240063665 | CHOWDHURY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kaushik CHOWDHURY (Needham, Massachusetts); Yousof NADERI (Brookline, Massachusetts) |
| ABSTRACT | Sensing and charging of electronic devices using coils. A software-defined collaborative sensing approach can allow detection and location of multiple electronic devices with respect to a charging surface to allow for wireless charging thereof. Systems and methods can measure the interaction of devices with a generated magnetic field through a network of nested sensing coils that can sense the location of devices located around the network of coils based on their interaction with magnetic fields. Once the location of a device to be charged is determined, charging energy can be directed to the device based on its location on the charging surface. The charging surface can include one or more sensing nodes having a combination of nested active, or driven, and passive coils. These coils can be configured to transform existing two-dimensional (2D) surfaces or three-dimensional (3D) areas into a multi -device contactless wireless charger. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/766325 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/10 (20160201) H02J 50/90 (20160201) Original (OR) Class H02J 50/402 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240065088 | Eze et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vincent O. Eze (Tallahassee, Florida); Okenwa Okoli (Tallahassee, Florida) |
| ABSTRACT | Organic photovoltaic materials (OPV) and devices using the same are provided, as well as methods of fabricating and using the same. An OPV material can be used as a photo-absorbing layer for mechanoluminescent (ML) light (e.g., in a flexible organic ML photodiode). The OPV material can include, for example, a blend of a donor polymer (e.g., P3HT) and a non-halogenated, non-fullerene acceptor (e.g., Y6). |
| FILED | Thursday, August 17, 2023 |
| APPL NO | 18/451350 |
| CURRENT CPC | Organic electric solid-state devices H10K 30/50 (20230201) H10K 85/113 (20230201) Original (OR) Class H10K 85/626 (20230201) H10K 85/657 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240057729 | Boyce et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brad Boyce (Albuquerque, New Mexico); Philip Noell (Albuquerque, New Mexico); Nicholas Leathe (Albuquerque, New Mexico); Ophelia Bolmin (Albuquerque, New Mexico); Benjamin Young (Albuquerque, New Mexico) |
| ABSTRACT | Additive manufacturing (AM) can be used to fabricate a wide palette of interlocking metasurfaces (ILMs). ILMs can be architecturally tailored to achieve intentional engagement and disengagement forces, and are amenable to topological optimization. ILMs can be fabricated using nearly any AM process at different length scales according to the capabilities of the process. As a result, ILMs represent a new class of joining technology enabled by additive manufacturing that is complementary to traditional joining processes including fasteners, welds, adhesives, etc. |
| FILED | Tuesday, August 16, 2022 |
| APPL NO | 17/888846 |
| CURRENT CPC | Buttons, Pins, Buckles, Slide Fasteners, or the Like A44B 18/0053 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058745 | Akpolat |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GTI ENERGY (Des Plaines, Illinois) |
| ASSIGNEE(S) | GTI ENERGY (Des Plaines, Illinois) |
| INVENTOR(S) | Osman Akpolat (Northbrook, Illinois) |
| ABSTRACT | A system and method for removing a component from a gas stream. The method includes absorbing the component from a gas stream in a solvent, separating the component from the solvent, and recycling the solvent back to the absorbing step. The absorbing is desirably performed by a counter-current contact between the solvent and the gas stream, such as using a rotating packed bed absorber. The rotating packed bed absorber is paired with a multistage solvent regeneration system configured to receive a rich solution from the rotating packed bed absorber and return a recycled lean solution to the rotating packed bed absorber. |
| FILED | Monday, August 14, 2023 |
| APPL NO | 18/233548 |
| CURRENT CPC | Separation B01D 53/18 (20130101) B01D 53/1425 (20130101) Original (OR) Class B01D 2258/0283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058864 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Iver E. Anderson (Ames, Iowa); Jordan A. Tiarks (Ames, Iowa); Timothy E. Prost (Ames, Iowa); Bo Kong (Ames, Iowa); Emma H. White (Ames, Iowa); Trevor M. Riedemann (Ames, Iowa); Eric J. Deaton (Ames, Iowa); Ross Anderson (Ames, Iowa); David Byrd (Ames, Iowa); Franz Hugolino Hernandez Gaitan (Ames, Iowa) |
| ABSTRACT | The broad applicability of at least certain aspects of the present invention derives from the ability to determine the critical location where secondary satellite formation occurs for any atomization system or design and allows for the rapid assessment of the effectiveness of various satellite reduction strategies, including but not limited to several embodiments detailed herein. Aspects of this invention can be utilized during initial atomization system design in order to evaluate effective chamber geometries and enabling strategies which reduce/eliminate satelliting, or can be retrofit to existing systems and allows for economic evaluation of effectiveness based off of initial capital expenditures versus increased operating requirements/expenses. |
| FILED | Tuesday, September 12, 2023 |
| APPL NO | 18/465392 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058891 | Whalen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott A. Whalen (West Richland, Washington); M.D. Reza-E-Rabby (Richland, Washington); Kenneth A. Ross (West Richland, Washington); Martin McDonnell (Sterling Heights, Michigan); Yuri Hovanski (Mapleton, Utah) |
| ABSTRACT | Methods are provided for connecting two dissimilar materials. The methods can include: placing a first material within a groove of a second material, the first material leaving at least a portion of the groove vacant; and placing a third material upon the first material and over the groove; heating the second and third materials to a temperature sufficient to plasticize the second and third materials within the groove and form a mixture of the second and third materials within the groove. Friction stir welding tools are also provided that can include a frusta conical tip having an upper portion defining smooth sidewalls and a lower portion defining a roughened structure. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/494648 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/127 (20130101) Original (OR) Class B23K 20/1255 (20130101) B23K 2103/10 (20180801) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/08 (20130101) B32B 15/012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059560 | Erlebacher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonah D. Erlebacher (Chevy Chase, Maryland); Shashank Vummidi Lakshman (Baltimore, Maryland); Jonathan Luke Horlyck (Washington, District of Columbia); Gina Reba Greenidge (Baltimore, Maryland) |
| ABSTRACT | A method of producing hydrogen includes subliming a metal salt comprising a metal and a halide to yield a gas phase metal salt comprising the metal and the halide, and contacting the gas phase metal salt with a gas phase hydrocarbon to yield the metal in elemental form, carbon in elemental form, hydrogen gas, and a hydrogen halide comprising the halide. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 18/271003 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/26 (20130101) Original (OR) Class C01B 2203/1058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059565 | Jasinski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacek B. Jasinski (Louisville, Kentucky); Hui Wang (Beijing, China PRC); Gamini Sumanasekera (Louisville, Kentucky); Usman Abu (Abuja, Nigeria); Sharmin Akter (Dhaka, Bangladesh) |
| ABSTRACT | Black phosphorous (BP) flakes are nanostructured via electrochemical intercalation of Na+ ions into bundles of phosphorene nanoribbons (PNRs). The large diffusion barrier of Na+ ions along the armchair direction leads to a well-defined columnar intercalation of Na+ ions in BP, resulting in the long zigzag-oriented columns of disordered material. The sonication of the bundles is then used to separate the PNRs. |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/450060 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 25/003 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/17 (20130101) C01P 2004/64 (20130101) C01P 2006/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059615 | Sant et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gaurav N. Sant (Los Angeles, California); Dale Prentice (Los Angeles, California); Dante Adam Simonetti (Los Angeles, California); Jenny Arabit (Los Angeles, California) |
| ABSTRACT | The present disclosure provides methods of preparing concrete products comprising carbonation of brucite-containing concrete. The present disclosure further provides brucite containing concrete mixtures that are useful in the present methods. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/217171 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 28/10 (20130101) Original (OR) Class C04B 40/0082 (20130101) C04B 40/0231 (20130101) C04B 40/0281 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059723 | KENT |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael S. KENT (Albuquerque, New Mexico) |
| ABSTRACT | The present invention provides for a method to break a C—C bond in lignosulfonate, the method comprising: (a) optionally sulfonating a lignin to produce a lignosulfonate, (b) contacting a chelator/Fe complex or a Fe(II) cation with a lignosulfonate to produce a reaction mixture, (c) incubating the reaction mixture for a suitable period of time wherein at least one C—C bond in a lignosulfonate is broken, (d) optionally introducing an oxidizing agent to the reaction mixture, and (e) optionally separating two separate molecules formed from breaking the C—C bond of lignosulfonate. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/494513 |
| CURRENT CPC | Compounds of Unknown Constitution C07G 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060037 | NORTH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Justin NORTH (Columbus, Ohio); Srividya MURALI (Dublin, Ohio); Sarah YOUNG (Gahanna, Ohio); Fred TABITA (, None) |
| ABSTRACT | The present disclosure provides non-naturally occurring microbial organisms capable of producing ethylene, ethane, and/or methane, as well was methods for producing ethylene, ethane, and/or methane using the same. |
| FILED | Monday, September 25, 2023 |
| APPL NO | 18/473637 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) Original (OR) Class C12N 9/88 (20130101) C12N 9/0095 (20130101) C12N 9/1007 (20130101) C12N 15/63 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/02 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/01 (20210501) Enzymes C12Y 118/00 (20130101) C12Y 201/01251 (20150701) C12Y 404/01011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060157 | YANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | YING YANG (Farragut, Tennessee); LING WANG (Fremont, California); LIZHEN TAN (Knoxville, Tennessee); YUTAI KATO (Kingston, Tennessee); LANCE L. SNEAD (Stony Brook, New York); STEVEN J. ZINKLE (Knoxville, Tennessee) |
| ABSTRACT | A Cu-based alloy according to the present invention comprises 1.0-2.0 wt % Cr, 0.5-1.5 wt % Nb, 0.1-0.5 wt % Zr, and balance Cu. The alloy has a matrix and grain boundaries, and has Cr2Nb precipitates within the grain boundaries and at least one selected from the group consisting of CuZr and Cr precipitates in the grain matrix. The CuZr precipitates can be at least one selected from the group consisting of Cu5Zr and Cu51Zr14 precipitates. A method of making a CuCrNbZr alloy is also disclosed. |
| FILED | Wednesday, August 16, 2023 |
| APPL NO | 18/234461 |
| CURRENT CPC | Alloys C22C 1/02 (20130101) C22C 9/00 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/002 (20130101) C22F 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060158 | LUO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aihua LUO (Westerville, Ohio); Emre CINKILIC (Columbus, Ohio); Michael MOODISPAW (Powell, Ohio) |
| ABSTRACT | Disclosed herein are aluminum alloys and methods of making and use thereof. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 18/278916 |
| CURRENT CPC | Alloys C22C 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060164 | BRADY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MICHAEL P. BRADY (Oak Ridge, Tennessee); GOVINDARAJAN MURALIDHARAN (Knoxville, Tennessee); YUKINORI YAMAMOTO (Knoxville, Tennessee) |
| ABSTRACT | A cast AFA alloy composition comprising, in weight percent: 0.4 to 0.59 Nb+Ta; 0.4 to 0.6 C; 16 to 18 Cr; 18-23 Ni; 3.5-5.5 Al; 0.005 to 0.15 B; up to 1.5 Mo; up to 2 Co; up to 1 W; up to 3 Cu; up to 4 Mn; up to 2 Si; up to 0.5 wt. % total of at least one element selected from the group consisting of Ti and V; up to 0.06 N; up to 1 wt. % total of at least one element selected from the group consisting of Y, La, Ce, Hf, and Zr; balance Fe, wherein the weight percent Fe is greater than the weight percent Ni, and wherein the alloy forms an external continuous scale comprising alumina to at least 900° C. in air with 10% H2O, and a stable essentially single-phase FCC austenitic matrix microstructure, the austenitic matrix being essentially delta-ferrite free and essentially BCC-phase-free, with creep rupture life in excess of 500 h at 900° C. and 50 MPa. |
| FILED | Monday, August 21, 2023 |
| APPL NO | 18/236326 |
| CURRENT CPC | Alloys C22C 30/02 (20130101) C22C 38/02 (20130101) C22C 38/04 (20130101) C22C 38/005 (20130101) C22C 38/06 (20130101) C22C 38/42 (20130101) C22C 38/44 (20130101) C22C 38/48 (20130101) C22C 38/50 (20130101) C22C 38/54 (20130101) C22C 38/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060194 | Stone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Twelve Benefit Corporation (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Simon Gregory Stone (Arlington, Massachusetts); Steven George Goebel (Victor, New York); Timothy A. Bekkedahl (Fremont, California); Emerson Gallagher (Vancouver, British Columbia, Canada); Bevan Moss (Vancouver, British Columbia, Canada); Sichao Ma (Dublin, California); Noel Farrell (Vancouver, British Columbia, Canada); Dave Whittaker (Richmond, California) |
| ABSTRACT | Various COx electrolyzer multi-cell architectures are provided, including various frame, flow field, gas diffusion layer, and repeat unit designs that may be particularly useful in the context of multi-cell COx electrolyzer cells. |
| FILED | Monday, June 05, 2023 |
| APPL NO | 18/329524 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/23 (20210101) Original (OR) Class C25B 9/19 (20210101) C25B 9/40 (20210101) C25B 9/63 (20210101) C25B 11/032 (20210101) C25B 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060199 | VARDNER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Jonathan VARDNER (New York, New York); Alan WEST (Tenafly, New Jersey); Scott BANTA (Fairfield, Connecticut) |
| ABSTRACT | A copper concentrate such as chalcopyrite is contacted with an aqueous solution includes acids and a reducing agent, such as vanadium (II) ions, chromium (II) ions, or tungstozincic acid (H6ZnW12O40). The aqueous solution reduces the copper in the copper concentrate, which can then dissolve into the solution for recovery therefrom, or precipitate out of solution as copper compounds or elemental copper for recovery in as a solid phase product. The solid phase product can then be isolated, dissolved, and further electrowinned to recover a copper product from the copper concentrate. Oxidized reducing agent can be recovered in an electrochemical device with ferrous iron reactants. Hydrometallurgical routes to convert copper concentrates to copper are potentially less expensive and less polluting than current pyrometallurgical processing and an advantageous response to environmental and economic pressures for increased copper production. |
| FILED | Wednesday, December 29, 2021 |
| APPL NO | 18/270560 |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240060864 | FITZCHARLES et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nikita Susan Dutta FITZCHARLES (Denver, Colorado); Rory Patrick ANDRYKOWSKI (Sedalia, Colorado); Steven Scott ROBBINS (Arvada, Colorado); Katherine Leigh JUNGJOHANN (Littleton, Colorado) |
| ABSTRACT | Described herein are devices and methods for flash freezing samples while applying an in situ electrical current or bias. Advantageously, the present application is directed towards materials, such as batteries or electrochemical cells, where applying an electrical current or bias leads to dynamic changes to the structure and chemistry of constituent materials, which underpin device performance and degradation. By concurrently applying electrical current or bias and flash freezing the sample, transient structures in the anode, cathode, or electrolyte can be observed with a high degree of temporal resolution at an atomic scale. |
| FILED | Monday, August 21, 2023 |
| APPL NO | 18/452782 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/508 (20130101) B01L 2300/0832 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/42 (20130101) Original (OR) Class G01N 27/4161 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) H01J 37/263 (20130101) H01J 2237/2001 (20130101) H01J 2237/2007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061181 | Ardalan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ayar Labs, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shahab Ardalan (Santa Clara, California); Michael Davenport (Santa Barbara, California); Roy Edward Meade (Lafayette, California) |
| ABSTRACT | A package assembly includes a silicon photonics chip having an optical waveguide exposed at a first side of the chip and an optical fiber coupling region formed along the first side of the chip. The package assembly includes a mold compound structure formed to extend around second, third, and fourth sides of the chip. The mold compound structure has a vertical thickness substantially equal to a vertical thickness of the chip. The package assembly includes a redistribution layer formed over the chip and over a portion of the mold compound structure. The redistribution layer includes electrically conductive interconnect structures to provide fanout of electrical contacts on the chip to corresponding electrical contacts on the redistribution layer. The redistribution layer is formed to leave the optical fiber coupling region exposed. An optical fiber is connected to the optical fiber coupling region in optical alignment with the optical waveguide within the chip. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/499093 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/30 (20130101) Original (OR) Class G02B 6/122 (20130101) G02B 6/428 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061440 | Chowdhary et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Girish Chowdhary (Champaign, Illinois); Chinmay P. Soman (Urbana, Illinois); Erkan Kayacan (Champaign, Illinois); Benjamin C. Thompson (Chcago, Illinois); Zhongzhong Zhang (Urbana, Illinois); Anwesa Choudhuri (West Bengal, India) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, obtaining video data from a single monocular camera, wherein the video data comprises a plurality of frames, wherein the camera is attached to a mobile robot that is travelling along a lane defined by a row of crops, wherein the row of crops comprises a first plant stem, and wherein the plurality of frames include a depiction of the first plant stem; obtaining robot velocity data from encoder(s), wherein the encoder(s) are attached to the robot; performing foreground extraction on each of the plurality of frames of the video data, wherein the foreground extraction results in a plurality of foreground images; and determining, based upon the plurality of foreground images and based upon the robot velocity data, an estimated width of the first plant stem. Additional embodiments are disclosed. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/486909 |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0246 (20130101) Original (OR) Class Electric Digital Data Processing G06F 18/2155 (20230101) Computer Systems Based on Specific Computational Models G06N 20/10 (20190101) Image or Video Recognition or Understanding G06V 20/41 (20220101) G06V 20/188 (20220101) Wireless Communication Networks H04W 4/40 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062075 | SHRIVER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cole GENTRY (Oak Ridge, Tennessee); University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Forrest SHRIVER (Gainesville, Florida); Justin WATSON (Gainesville, Florida); Cole Andrew GENTRY (Oak Ridge, Tennessee) |
| ABSTRACT | Various examples are related to prediction of neutronics parameters using deep learning. In one embodiment, a method includes generating a training data set based upon one or more principled approaches that provide a gradient of values; generating a neural network using structured or unstructured sampling of a hyperparameter space augmented by probabilistic machine learning; training the generated neural network based on the training data set to produce one or more neutronics parameters; and generating at least one neutronics parameter utilizing the trained neural network. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 18/266367 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/047 (20230101) G06N 3/0985 (20230101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062925 | Gerczak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tyler J. Gerczak (Oak Ridge, Tennessee); John D. Hunn (Oak Ridge, Tennessee); Richard A. Lowden (Oak Ridge, Tennessee) |
| ABSTRACT | A TRISO architecture including an improved buffer layer is provided. The improved buffer layer contains sacrificial silicon in low density carbon to react with palladium released from the kernel and thereby limit the palladium available to react with the existing SiC layer. The introduction of silicon in the buffer layer allows for longer fuel lifetimes and/or higher operating temperatures. Higher achievable burnups and operational temperatures can reduce fuel costs and achieve higher efficient power production. In addition, the silicon-containing buffer layer mitigates fuel failure from palladium corrosion, thereby increasing the safety of the TRISO fuel particle. |
| FILED | Thursday, August 03, 2023 |
| APPL NO | 18/229833 |
| CURRENT CPC | Nuclear Reactors G21C 21/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240062928 | Said et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Ayman H. Said (Lombard, Illinois); Thomas Gog (Woodridge, Illinois); Jung Ho Kim (Naperville, Illinois); Emily K. Aran (Westchester, Illinois) |
| ABSTRACT | The invention provides a method for fabricating analyzers, the method comprising providing a radiation manipulating material on a first surface of a flexible support; contacting a second surface of the flexible support to a permeable mold, wherein the mold has a first flexible support contact surface and a second surface; and applying negative pressure to the second side of the flexible support to cause the flexible support to conform to the first flexible support contact surface of the mold. Also provided is a system for fabricating crystal analyzers, the system comprising crystal structures reversibly attached to a flexible support; a porous mold reversibly contacting the flexible support, wherein the mold defines a topography; and a negative pressure applied to the flexible support to cause the crystal structures to conform to the topography. |
| FILED | Friday, August 19, 2022 |
| APPL NO | 17/892020 |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/06 (20130101) Original (OR) Class G21K 2201/062 (20130101) G21K 2201/064 (20130101) G21K 2201/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240063088 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Yongduk Lee (Vernon, Connecticut); Ankit Gupta (Willimantic, Connecticut); Parag M. Kshirsagar (South Windsor, Connecticut) |
| ABSTRACT | Embodiments have two approaches as follows: (1) Embedded PCB-based fabrication and (2) PCB assembly-based fabrication. An embedded printed circuit board (PCB) type approach involves the creation of a space of coolant direct interconnection, using immersion cooling to link on any type of power semiconductor device hot spots to convectively and evaporatively cool directly. This means fabricating PCB embedded channels, to utilize the microgap between die and PCB as the cooling channel. A printed circuit board (PCB) assembly embodiment includes a PCB having at least one heat generating component. A lid is mounted to the PCB, wherein the lid defines a cooling path therein extending in a coolant flow direction from an inlet end of the cooling path to an outlet end of the cooling path. |
| FILED | Wednesday, August 17, 2022 |
| APPL NO | 17/889511 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/445 (20130101) Original (OR) Class H01L 23/473 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0203 (20130101) H05K 7/20236 (20130101) H05K 7/20272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240063597 | Nguyen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hoang T. Nguyen (Livermore, California); Michael C. Rushford (Livermore, California); Brad Hickman (Ripon, California) |
| ABSTRACT | A spectral beam combining system includes a spectral channel splicer comprising a plurality of reflectors and a spectral beam combiner comprising a diffraction optical element such as a diffraction grating. The spectral beam combining system may further comprise at least one additional diffractive optical element or diffraction grating for dispersion compensation that reduces the effects of angular dispersion of wavelength components within the input channel. This spectral beam combining system facilitates combining an increased number of wider spectral channels thereby potentially allowing higher optical power, e.g., within each fewer channel lasers. The combined beam focal spot shape profile is maintained as spectrum width or central spectrum wavelength of any one or all input channels is changed. |
| FILED | Wednesday, November 01, 2023 |
| APPL NO | 18/500035 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0944 (20130101) G02B 27/1006 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/005 (20130101) Original (OR) Class H01S 3/2391 (20130101) H01S 3/08009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240064887 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Z. Xu (Naperville, Illinois); Maofei Qian (Darien, Illinois); Alexander A. Zholents (Marina Del Rey, California) |
| ABSTRACT | Employing undulator devices as x-ray radiation sources requires expensive and bulky support systems for operation, which are not robust and lead to limited ranges of generated radiation energies. A force-compensated undulator device is described. The device includes an undulator having first and second magnet arrays disposed along a central axis. The first magnet array is translatable along the central axis. The device further includes a compensator unit disposed adjacent to the first magnet array with the compensator unit having a first row of magnets disposed along a compensator axis with the compensator axis being parallel to the central axis, and a second row of magnets disposed along the compensator axis. The first row of magnets is translatable along the compensator axis. The compensator provides magnetic forces that neutralize the system dynamic magnetic forces generated by the undulator. |
| FILED | Friday, August 19, 2022 |
| APPL NO | 17/891769 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0959 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/04 (20130101) Original (OR) Class H05H 13/04 (20130101) H05H 2007/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240065115 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Huang Family Corp. (Castro Valley, California) |
| ASSIGNEE(S) | Huang Family Corporation (Castro Valley, California) |
| INVENTOR(S) | Kevin Huang (Livermore, California); Gianpaolo Carosi (Livermore, California); Yaniv J. Rosen (Livermore, California); Nathan Woollett (Witney, United Kingdom) |
| ABSTRACT | An apparatus includes a first superconductor layer, an insulating layer, and a second superconductor layer, wherein the second superconductor layer is a spin triplet superconductor (STS) layer. In some embodiments, the first superconductor layer is also a STS layer. In some embodiments, the second superconductor layer includes UCoGe. In some embodiments, the insulating layer includes uranium oxide. In some embodiments, the uranium oxide is created by exposing the second superconductor layer to an oxidizing gas, with or without heating. In some embodiments, the first superconductor layer, the insulating layer and the second superconductor layer form a Josephson junction. |
| FILED | Wednesday, August 17, 2022 |
| APPL NO | 17/890215 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/025 (20130101) H01L 39/223 (20130101) Original (OR) Class H01L 39/2493 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20240057874 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Nathaniel Braman (Bethel Park, Pennsylvania) |
| ABSTRACT | The present disclosure relates to a method. The method may be performed by accessing data derived from one or more routine clinical medical imaging scans including a lesion in which the lesion and associated vasculature are segmented in a three-dimensional segmentation. At least two features are extracted from the three-dimensional segmentation of the associated vasculature. The at least two features include at least one feature indicative of a morphology of the associated vasculature or a portion thereof, and at least one feature indicative of a function of the associated vasculature or a portion thereof. The at least two features, and/or one or more statistics of the at least two features, are provided to a machine learning model trained to make a prediction concerning the lesion. The prediction concerning the lesion is received from the machine learning model. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/495821 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/004 (20130101) A61B 5/08 (20130101) A61B 5/0035 (20130101) A61B 5/02007 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/12 (20170101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20036 (20130101) G06T 2207/20081 (20130101) G06T 2207/30061 (20130101) G06T 2207/30068 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058223 | Kearns et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Diehl Kearns (Tampa, Florida); Kimberly Ann Crosland (Lithia, Florida); Jeffrey D. Craighead (Groveland, Florida); James Leonard Fozard (Palm Harbor, Florida) |
| ABSTRACT | A medication adherence system and corresponding medication box for improving medication adherence. The system includes the medication box, which is transparent and has a machine-readable marker, such as a QR code, on or beneath the floor thereof. The marker is capable of being scanned and read through the transparent bottoms of individual chambers. Data embedded in the marker includes, but is not limited to, the user's medication plan, the date and time when the medication is to be ingested, and instructions for recording the date and time when the marker is scanned and read. The underlying software program/application processes this information and provides an indication as to the user's compliance with the medication plan. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498333 |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 7/0069 (20130101) A61J 7/0076 (20130101) A61J 7/0092 (20130101) A61J 7/0418 (20150501) A61J 7/0445 (20150501) A61J 7/0481 (20130101) Original (OR) Class A61J 2200/30 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/06028 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/13 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058283 | Barnett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | West Virginia University Board of Governors on Behalf of West Virginia University (Morgantown, West Virginia); Temple University-Of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania); University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John B. Barnett (Morgantown, West Virginia); Werner Geldenhuys (Morgantown, West Virginia); Jonathan Soboloff (Philadelphia, Pennsylvania); Harry C. Blair (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of restoring the balance of osteoclast to osteoblast activity in a patient having rheumatoid arthritis comprising administering to a patient a therapeutically effective amount of the compound N-(3,4-dichlorophenyl)-N-methylpropanamide is provided. A method for treating arthritis-induced bone erosion in a patient comprising administering to a patient a therapeutically effective amount of the compound N-(3,4-dichlorophenyl)-N-methylpropanamide is provided. The compound N-(3,4-dichlorophenyl)-N-methylpropanamide is administered in a pharmaceutically acceptable composition to said patient. A mode of action of N-(3,4-dichlorophenyl)-N-methyl propanamide comprising targeting transient receptor potential channels is provided. |
| FILED | Friday, June 16, 2023 |
| APPL NO | 18/336712 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058357 | Forrest et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kessler Foundation Inc. (East Hanover, New Jersey); The United States Government as represented by The Department of Veterans Affairs (washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gail Florence Forrest (Cranbury, New Jersey); William A. Bauman (New Rochelle, New York) |
| ABSTRACT | Provided is a method for treating musculoskeletal atrophy in patients suffering from a neurological or neuromuscular disease or disorder by combining testosterone replacement therapy with neuromuscular electrical stimulation of multiple muscle groups and, optionally, physical activity. |
| FILED | Wednesday, November 01, 2023 |
| APPL NO | 18/386077 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/008 (20130101) A61H 2201/105 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 9/7023 (20130101) A61K 31/568 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/00 (20130101) A61N 1/04 (20130101) A61N 1/05 (20130101) A61N 1/08 (20130101) A61N 1/18 (20130101) A61N 1/32 (20130101) A61N 1/36 (20130101) A61N 1/0452 (20130101) A61N 1/36003 (20130101) Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 23/0405 (20130101) A63B 2213/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240058374 | Kennedy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Virginia Commonwealth University (Richmond, Virginia); GlycoMira Therapeutics, Inc. (Salt Lake City, Utah); Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas P. Kennedy (Williamsburg, Virginia); Bhaumik B. Patel (Glen Allen, Virginia) |
| ABSTRACT | Described herein are methods for preventing a relapse of cancer in a subject. The methods involve administering to the subject in need thereof a sulfated glycosaminoglycan or the pharmaceutically acceptable salt or ester thereof. In one aspect, the methods described herein prevent the growth or self-renewal of cancer stem cells in a subject. In another aspect, the methods described herein kill active or dormant cancer stem cells in a subject. The methods described herein can be used in combination with chemotherapy and/or radiation. The methods described herein are versatile with respect to preventing the relapse of a number of different cancers. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 18/264879 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) A61K 31/737 (20130101) Original (OR) Class A61K 33/243 (20190101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240057536 | Singer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Jonathan Singer (New Brunswick, New Jersey); Seyyed Rahman Pejman (New Brunswick, New Jersey); Arend-Jan Both (New Brunswick, New Jersey); David Specca (New Brunswick, New Jersey); Michael J. Grzenda (New Brunswick, New Jersey) |
| ABSTRACT | Various embodiments comprise systems, methods, mechanisms, and apparatus for holding an amount of rooting (growing) media in which plant roots develop that electrically isolate the plant roots from an electric field used to deliver water and plant nutrients to that rooting media via a high-voltage, low-current electrospray system. |
| FILED | Tuesday, August 22, 2023 |
| APPL NO | 18/236765 |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 31/02 (20130101) Original (OR) Class Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/1608 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240059873 | KORNFIELD et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (PASADENA, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julia A. KORNFIELD (PASADENA, California); Ming-Hsin WEI (PASADENA, California); Simon JONES (WHITTIER, California); Virendra SAROHIA (ALTADENA, California) |
| ABSTRACT | Described herein are associative polymers capable of controlling one or more physical and/or chemical properties of non-polar compositions and related compositions, methods and systems. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169389 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/008 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 11/00 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 101/02 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/198 (20130101) C10L 1/1973 (20130101) C10L 1/1976 (20130101) C10L 1/2366 (20130101) C10L 1/2368 (20130101) C10L 10/00 (20130101) C10L 10/02 (20130101) C10L 10/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240063012 | Park et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eden Park Illumination, Inc. (Champaign, Illinois); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sehyun Park (Anyang-si, South Korea); Sung-Jin Park (Champaign, Illinois); Andrey Mironov (Savoy, Illinois); James Gary Eden (Mahomet, Illinois) |
| ABSTRACT | A plasma lamp is provided that employs excitation transfer between two atomic or molecular species so as to preferentially produce light at a specific atomic or molecular emission wavelength. The lamp includes a lamp body. The lamp body includes a top portion, a middle portion having an internal hollow space filled with an energy-donor chemical gas and an energy-acceptor chemical element, and a bottom portion. The lamp body further includes an array of a plurality of cavities connected to the internal hollow space. The internal hollow space and the array of the plurality of cavities are spaced apart from outer surfaces of the lamp body. The plasma lamp is configured to excite the energy-donor chemical gas by an ignition of a low-temperature plasma within the internal hollow space and the array of the plurality of cavities to cause an excitation transfer from the excited energy-donor chemical gas to the energy-acceptor chemical element, thereby emitting radiation having a wavelength of about 194 nm when mercury (Hg) is the energy-acceptor chemical element and helium (He) serves as the donor. Other wavelengths in the ultraviolet (UV) and vacuum ultraviolet (VUV) spectral regions are generated when other donor and acceptor atoms or molecules are employed. These lamps are well-suited as optical drivers for atomic clocks (such as the 40.5 GHz Hg ion clock), photochemical processing of materials, disinfection of water, air, and surfaces, as well as other applications requiring UV or VUV light. |
| FILED | Tuesday, August 22, 2023 |
| APPL NO | 18/236568 |
| CURRENT CPC | Time-interval Measuring G04F 5/14 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 61/06 (20130101) H01J 61/16 (20130101) H01J 61/20 (20130101) Original (OR) Class H01J 61/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20240057527 | KARYDIS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Konstantinos KARYDIS (Laguna Beach, California); Merrick CAMPBELL (Riverside, California); Amel DECHEMI (Riverside, California) |
| ABSTRACT | Disclosed herein is a system and methods for leaf detection and extraction. The extracted leaf may be used for leaf water potential analysis. In some embodiments, the method comprises identifying the leaf from a point cloud based on an image, determining a pose of the leaf based on the point cloud, and cutting and storing the leaf based on the pose of the leaf. |
| FILED | Tuesday, August 22, 2023 |
| APPL NO | 18/453908 |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 3/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/08 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/70 (20170101) G06T 2207/10028 (20130101) G06T 2207/30188 (20130101) G06T 2207/30252 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240057570 | Fahrenkrug et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Recombinetics, Inc. (Eagan, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott C. Fahrenkrug (Minneapolis, Minnesota); Daniel F. Carlson (Woodbury, Minnesota) |
| ABSTRACT | Methods, uses, and animals for introgression of alleles between animals, including SNPs. One embodiment involves introducing a targeted targeting endonuclease system and a HDR template into a cell with a mismatch in the binding of the targeting endonuclease and the targeted site. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/933367 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) Original (OR) Class Peptides C07K 14/47 (20130101) C07K 14/715 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/907 (20130101) C12N 15/8509 (20130101) C12N 15/8771 (20130101) C12N 15/8778 (20130101) C12N 2750/14143 (20130101) C12N 2800/30 (20130101) C12N 2800/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20240058062 | Borsic |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NE Scientific, LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrea Borsic (Torino, Italy) |
| ABSTRACT | A system and method of modeling a necrotized tissue in an ablation procedure, the method comprising providing, at a computational component, a computer model of a volume of human tissue, simulating, by the computational component, an ablation site in the computer model, determining, by the computational component, a deposited power density relating to at least an ablation parameter using at least an ablation mode, determining, by the computational component, a heat distribution at the ablation site as a function of the deposited power density, and identifying, by the computational component, a volume of tissue necrotized during an ablation procedure performed at the ablation site. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 18/267169 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 34/10 (20160201) Original (OR) Class A61B 90/37 (20160201) A61B 2018/00577 (20130101) A61B 2034/104 (20160201) A61B 2034/105 (20160201) A61B 2034/107 (20160201) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/62 (20170101) G06T 19/003 (20130101) G06T 19/20 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240061375 | DeLacy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ballydel Technologies, Inc. (Wilmington, Delaware) |
| ASSIGNEE(S) | Ballydel Technologies, Inc. (Wilmington, Delaware) |
| INVENTOR(S) | Brendan G. DeLacy (Wilmington, Delaware); Mark S. Mirotznik (Wilmington, Delaware); Benjamin S. Garrett (Wilmington, Delaware) |
| ABSTRACT | A computerized system for uniquely tagging and verifying authenticity of an article comprising: an object having a surface; a computer system adapted to: receive a three-dimensional predetermined image, create a holographic interference pattern created according to the three-dimensional predetermined image and at least one physical property of the surface of the object, wherein the holographic interference pattern is applied to the object, project a three-dimensional resulting image projected on a planar surface in response to the holographic interference pattern being illuminated wherein the computer system receives the three-dimensional resulting image, creates validation information according to a comparison of the three-dimensional predetermined image and the three-dimensional resulting image. In one embodiment, the holographic interference pattern is illuminated by a beam of light that is directed to the interference pattern by a beam splitter, thus causing the three-dimensional resulting image to be projected on the planar surface. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498749 |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/0011 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 20240057557 | GILES et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE FEDERAL BUREAU OF INVESTIGATION (Washington, District of Columbia); AUBURN UNIVERSITY (Auburn, Alabama) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE FEDERAL BUREAU OF INVESTIGATION (Washington, District of Columbia); AUBURN UNIVERSITY (Auburn, Alabama) |
| INVENTOR(S) | Kathleen GILES (Washington, District of Columbia); Thomas Craig ANGLE (Auburn, Alabama); Lowell Paul WAGGONER (Auburn, Alabama); Thomas PASSLER (Auburn, Alabama); Terrence FISCHER (Auburn, Alabama) |
| ABSTRACT | Provided herein are methods of making a training aid for detecting a biohazard, and related devices and methods of using the device, including a canine training aid. The devices are made by positioning a polymer layer in proximity and physically separated from a biological material, so that volatile organic compounds contact and bind or infuse the polymer layer. The device is made render-safe by inactivating the infused polymer layer, such as by heating to a temperature sufficient to inactivate biological agents on or in the analyte-infused polymer layer. The device can be stored in a substantially air-tight configuration for subsequent use in training, such as canine and/or or artificial detectors. |
| FILED | Tuesday, May 30, 2023 |
| APPL NO | 18/325290 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 15/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
| US 20240059094 | Rich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WAVEFRONT TECHNOLOGY, INC. (Paramount, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Chapman Rich (Rancho Palos Verdes, California); Joel Mikael Petersen (Valley Village, California); John Michael Tamkin (Pasadena, California); Roger Winston Phillips (Santa Rosa, California); Phillip Christopher Harvey (Long Beach, California) |
| ABSTRACT | An optical product can reproduce a first 3D image of at least part of a first 3D object and a second 3D image of at least part of a second 3D object. The optical product comprises a surface configured, when illuminated, to reproduce by reflected or transmitted light, the first 3D image without reproducing the second 3D image at a first angle of view, and the second 3D image without reproducing the first 3D image at a second angle of view. Each portion of first portions can correspond to a point on a surface of the first 3D object, and comprise first non-holographic features configured to produce at least part of the first 3D image. Each portion of second portions can correspond to a point on a surface of the second 3D object, and comprise second non-holographic features configured to produce at least part of the second 3D image. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/174510 |
| CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/21 (20141001) B42D 25/29 (20141001) B42D 25/324 (20141001) B42D 25/342 (20141001) Original (OR) Class B42D 25/351 (20141001) B42D 25/355 (20141001) B42D 25/373 (20141001) B42D 25/378 (20141001) B42D 25/425 (20141001) Optical Elements, Systems, or Apparatus G02B 5/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240222.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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