FedInvent™ Patent Applications
Application Details for Thursday, February 29, 2024
This page was updated on Tuesday, June 18, 2024 at 02:15 PM GMT
Department of Health and Human Services (HHS)
| US 20240065544 | JIA et al. |
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| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Yali JIA (Portland, Oregon); Jie WANG (Portland, Oregon) |
| ABSTRACT | Disclosed are methods and systems for signal attenuation-compensated projection-resolved (sacPR) optical coherence tomography angiography (OCTA). The sacPR OCTA may be free of segmentation and vascular contrast enhancement. In some embodiments, projection artifacts may be suppressed with signal compensation including flow and large vessel shadow compensation for projection removal and wavelet-based compensation for noise suppression. |
| FILED | Thursday, August 24, 2023 |
| APPL NO | 18/455154 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/102 (20130101) Original (OR) Class A61B 5/0066 (20130101) A61B 5/7203 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/009 (20130101) G06T 7/0012 (20130101) G06T 2207/10101 (20130101) G06T 2207/20021 (20130101) G06T 2207/20064 (20130101) G06T 2207/20201 (20130101) G06T 2207/30041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240065555 | Hu et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peng Hu (Pasadena, California); Lihong Wang (Arcadia, California) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of systems and methods of imaging using photoacoustic computed tomography. |
| FILED | Wednesday, August 16, 2023 |
| APPL NO | 18/450597 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0095 (20130101) Original (OR) Class A61B 5/725 (20130101) Image Data Processing or Generation, in General G06T 11/008 (20130101) G06T 2210/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240065572 | Galeotti et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania); University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Michael Galeotti (Pittsburgh, Pennsylvania); George DeWitt Stetten (Pittsburgh, Pennsylvania); Chun-Yin Huang (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided is a system, method, and computer program product for tracking an object based on skin images. A method includes capturing, with at least one computing device, a sequence of images with a stationary or movable camera unit arranged in a room, the sequence of images including the subject and an object moving relative to the subject, and determining, with at least one computing device, the pose of the object with respect to the subject in at least one image of the sequence of images based on computing or using a prior surface model of the subject, a surface model of the object, and an optical model of the stationary or movable camera unit. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/280283 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/061 (20130101) Original (OR) Class A61B 5/0077 (20130101) A61B 5/742 (20130101) Image Data Processing or Generation, in General G06T 7/75 (20170101) G06T 7/246 (20170101) G06T 2207/10132 (20130101) G06T 2207/20016 (20130101) G06T 2207/30088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240065603 | GEORGE |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob A. GEORGE (Salt Lake City, Utah) |
| ABSTRACT | A grip gauge is configured to measure grip force from a single hand of a user. The grip gauge comprises a shell and a force sensor housed within the shell. The force sensor is configured to measure grip forces applied to the shell. The grip gauge also includes a control unit housed within the shell and communicatively connected to the force sensor, and a wireless transmitter communicatively connected to the control unit and configured to transmit measured grip forces to one or more external devices. |
| FILED | Friday, March 03, 2023 |
| APPL NO | 18/117316 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/225 (20130101) Original (OR) Class A61B 2560/0462 (20130101) A61B 2562/06 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240065981 | Wolcott et al. |
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| APPLICANT(S) | San Jose State University (San Jose, California) |
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| INVENTOR(S) | Abraham Wolcott (Scotts Valley, California); Krishna Govindaraju (Santa Clara, California); Sandra Ladjadj (San Jose, California); Daniel Labunsky (San Jose, California); Ezhioghode Uwadiale (San Jose, California) |
| ABSTRACT | Various aspects described herein relate to a functionalized nanoscale substrate. The functionalized nanoscale substrate includes a functionalized surface of the substrate that includes a boronated portion. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/454139 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 9/1277 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066009 | Haass-Koffler |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
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| INVENTOR(S) | Carolina L. Haass-Koffler (Providence, Rhode Island) |
| ABSTRACT | Stress responses involve corticotropin releasing factor (CRF), the two cognate receptors (CRF1 and CRF2) and the CRF-binding protein (CRFBP). Utilizing a novel cell-based assay, a C-terminal CRFBP fragment [CRFBP(10 kD)] was found to potentiates CRF-intracellular Ca2+ release, demonstrating that CRFBP possesses excitatory roles in addition to the inhibitory role established by the N-terminal fragment of CRFBP [CRFBP(27 kD)]. This interaction was CRF2-specific, as CRF1 responses were not potentiated by CRFBP(10 kD). As there were currently no small molecule ligands available that selectively interact with either CRFBP or CRF2, a cell-based assay was miniaturized, wherein CRFBP(10 kD) was fused as a chimera with CRF2α, that allowed us to a perform a high-throughput screen (HTS) of approximately 350,000 small molecules. This resulted in the identification of negative allosteric modulators (NAMs) of the CRFBP(10 kD)-CRF2 complex that blunt CRF-induced potentiation of N-Methyl-D-aspartic acid receptor (NMDAR)-mediated synaptic transmission in dopamine neurons in the ventral tegmental area (VTA). These results provide the first evidence of specific roles for CRF2 and CRFBP in the modulation of neuronal activity and suggest that NMDARs in the VTA may be a target for the treatment of stress and substance abuse disorders such as alcohol use disorder. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/486973 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) A61K 31/4245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066021 | Ziady et al. |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
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| INVENTOR(S) | Assem G. Ziady (Newport, Kentucky); Emily J. Skala (Cleves, Ohio); Maureen B. Dunn (Cincinnati, Ohio); Karen Lammers (North Bend, Ohio) |
| ABSTRACT | Disclosed are methods for the treatment of cystic fibrosis in an individual in need thereof. The methods may include the administration of a CFTR modulator, with or without and one or more CFTR modulator therapy optimizing agent. Further disclosed are methods for treating cystic fibrosis in an individual in need thereof which employ detection of one or more biomarkers which may be used to distinguish CFTR modulator responders and non-responders, which may in turn be used to direct therapy in an individual having cystic fibrosis. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 18/272176 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/47 (20130101) Original (OR) Class A61K 31/4025 (20130101) A61K 31/4439 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066022 | Seleem et al. |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Mohamed Seleem (Blacksburg, Virginia); Nader Abutaleb (Blacksburg, Virginia) |
| ABSTRACT | The present application generally relates to a method to treat a patient with a bacterial infection caused by Clostridium difficile. Particularly the method compromises the step of administering a therapeutically effective amount of diiodohydroxyquinoline, with or without one or more anti-infective agents, to the patient in need of relief from said infection. Methods of uses and composition matters are within the scope of this disclosure. |
| FILED | Monday, November 06, 2023 |
| APPL NO | 18/387450 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0053 (20130101) A61K 31/47 (20130101) Original (OR) Class A61K 31/4164 (20130101) A61K 31/7048 (20130101) A61K 38/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066023 | Cox et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sistema Universitario Ana G. Mendez, Inc. (San Juan, Puerto Rico) |
| ASSIGNEE(S) | Sistema Universitario Ana G. Mendez, Inc. (San Juan, Puerto Rico) |
| INVENTOR(S) | Osvaldo Cox (Humacao, Puerto Rico); Beatriz Zayas (San Juan, Puerto Rico) |
| ABSTRACT | A synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds is provided. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. Furthermore, anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303) are provided. |
| FILED | Monday, October 16, 2023 |
| APPL NO | 18/380245 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066035 | Cheng et al. |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
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| INVENTOR(S) | Shi-Yuan Cheng (Glenview, Illinois); Bo Hu (Glenview, Illinois); Tianzhi Huang (Chicago, Illinois) |
| ABSTRACT | Disclosed are methods and compositions for treating cell proliferative diseases and disorders such as cancers. Particularly disclosed are methods and composition for treating cancers such as glioblastoma by administering a therapeutic agent that inhibits the biological activity of the autophagy related 4B cysteine peptidase (ATG4B) protein in conjunction with additional therapeutic agents or treatments. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/468453 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/53 (20130101) A61K 31/427 (20130101) A61K 31/436 (20130101) A61K 31/437 (20130101) A61K 31/444 (20130101) A61K 31/495 (20130101) A61K 31/519 (20130101) A61K 31/5377 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066048 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Jian Liu (Chapel Hill, North Carolina); Zhangjie Wang (Changchun, China PRC); Po-Hung Hsieh (Pasadena, California); Yongmei Xu (Durham, North Carolina) |
| ABSTRACT | Heparin compounds and synthetic heparin analogues having short acting anticoagulant activity are provided. Methods of synthesizing such heparin compounds, including chemoenzymatic pathways using sulfotransferase enzymes are provided. Methods of treating subjects in need of anticoagulant activity are provided. |
| FILED | Monday, July 17, 2023 |
| APPL NO | 18/222910 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/727 (20130101) Original (OR) Class A61K 38/4846 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/02 (20180101) Polysaccharides; Derivatives Thereof C08B 37/0075 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) C12P 19/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066051 | LINHARDT et al. |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Robert John LINHARDT (Albany, New York); Fuming ZHANG (Watervliet, New York); Jawed FAREED (Westchester, Illinois); Walter JESKE (Woodridge, Illinois) |
| ABSTRACT | Prophylaxis and treatment of patients susceptible to infection by coronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is achieved using compositions including one or more inhibitors including sulfated glycans and/or highly negative charged compounds. The inhibitors bind to wild-type and variant spike glycoproteins (S-proteins or SGPs) of SARS-CoV-2, inhibiting fusion, entry, and infection of a host cell. The inhibitors can include pentosan polysulfate (PPS), mucopolysaccharide polysulfate (MPS), sulfated lactobionic acid, sulodexide, a defibrotide, 4-t-butylcalix[X] arene-p-sulfonic acid, or combinations thereof. The presence of additional sulfo groups in PPS and MPS contribute to the improved inhibitory activity of compositions with those sulfated glycans against COVID-19 compared with compositions containing heparin alone. The compositions can be formulated for nasal delivery to a patient, enabling a simplified treatment regimen effective against an ever increasing number of SARS-CoV-2 variants of concern. |
| FILED | Thursday, August 24, 2023 |
| APPL NO | 18/237624 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 31/737 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066067 | Almeida-Porada et al. |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina); Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maria Graca N.D. Almeida-Porada (Winston-Salem, North Carolina); Christopher D. Porada (Winston-Salem, North Carolina); Anthony Atala (Winston-Salem, North Carolina); Christopher B. Doering (Atlanta, Georgia); H. Trent Spencer (Marietta, Georgia) |
| ABSTRACT | Disclosed herein are method of treating hemophilia A in a subject comprising injecting the subject with mesenchymal stromal/stem cells (MSC) modified to express high levels of Factor VIII protein. The MSC are injected into the subject prenatally. The modified MSC may also express high levels von Willebrand factor protein. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/129399 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class Peptides C07K 14/755 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0668 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066072 | Kamada et al. |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nobuhiko Kamada (Ann Arbor, Michigan); Hiroko Kitamoto (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein is technology relating to preventing and treating gastrointestinal dysbiosis and particularly, but not exclusively, to compositions, methods, systems, and kits for treating and/or preventing Clostridioides difficile infection in an organism. |
| FILED | Monday, September 28, 2020 |
| APPL NO | 17/764878 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 38/20 (20130101) A61K 2035/115 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066074 | MOISEYENKO et al. |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anastasiya O. MOISEYENKO (Pasadena, California); Timothy R. SAMPSON (Pasadena, California); Sarkis K. MAZMANIAN (Pasadena, California) |
| ABSTRACT | Some embodiments herein relate generally to compositions comprising microbial organisms and/or components thereof for improving a neurological disorder, or symptoms associated with a neurological disorder, such as Parkinson's disease, and methods of using the same. |
| FILED | Tuesday, September 07, 2021 |
| APPL NO | 18/024477 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/741 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066079 | VARMA et al. |
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| APPLICANT(S) | PHI THERAPEUTICS, INC. (San Francisco, California) |
| ASSIGNEE(S) | PHI THERAPEUTICS, INC. (San Francisco, California) |
| INVENTOR(S) | Yug VARMA (San Francisco, California); Nancy VAN PROOYEN (San Francisco, California) |
| ABSTRACT | Provided herein are, inter alia, compositions, systems, and methods for preventing or treating acne. Included are compositions, combinations, systems, and methods comprising at least one Propionibacterium acnes bacteriophage, at least one anti-acne compound, and a pharmaceutically acceptable carrier. Also included are compositions, combinations, and systems comprising a Propionibacterium acnes bacteriophage and an enzyme. Methods for preventing or treating acne are also provided. |
| FILED | Thursday, August 11, 2022 |
| APPL NO | 17/819050 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/05 (20130101) A61K 31/60 (20130101) A61K 31/327 (20130101) A61K 33/04 (20130101) A61K 35/76 (20130101) Original (OR) Class A61K 35/741 (20130101) A61K 38/47 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/10 (20180101) Enzymes C12Y 302/01052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066096 | RESHETNYAK et al. |
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| APPLICANT(S) | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (Kingston, Rhode Island); YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yana K. RESHETNYAK (Saunderstown, Rhode Island); Oleg A. ANDREEV (Saunderstown, Rhode Island); Anna MOSHNIKOVA (Warwick, Rhode Island); Donald M. Engelman (New Haven, Connecticut) |
| ABSTRACT | The invention features methods and compositions for eliciting an anti-tumor response in a subject comprising administering to the subject a pHLIP● construct comprising an antibody recruiting molecule linked to one or more pHLIP● peptides by a non-cleavable linker compound. The construct increases the amount of the antibody recruiting molecule on the surface of a diseased cell. |
| FILED | Tuesday, May 30, 2023 |
| APPL NO | 18/325884 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) Original (OR) Class A61K 38/20 (20130101) A61K 38/195 (20130101) A61K 47/00 (20130101) A61K 2121/00 (20130101) Peptides C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066101 | Waller et al. |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Giacomo Waller (Atlanta, Georgia); Yiwen Li (Atlanta, Georgia); Edmund Waller (Atlanta, Georgia) |
| ABSTRACT | In certain embodiments, this disclosure relates to VIP and VIP agonists, optionally conjugated to nanoparticles, for use in methods of treating inflammatory T cell-mediated diseases or conditions, e.g., treating or preventing GvHD. In certain embodiments, this disclosure relates to methods of pulmonary administration of VIP and VIP agonists, optionally conjugated to nanoparticles. In certain embodiments, this disclosure contemplates nanoparticles disclosed herein. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/486860 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0075 (20130101) A61K 9/124 (20130101) A61K 38/26 (20130101) Original (OR) Class A61K 47/24 (20130101) A61K 47/6935 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066108 | Steinmetz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole F. Steinmetz (La Jolla, California); Steven Fiering (Hanover, New Hampshire); Courtney T. Stump (Hanover, New Hampshire) |
| ABSTRACT | Provided are compositions, methods and uses relating to an adjuvant which comprises, or consists essentially of, or consists of a cowpea mosaic virus (CPMV) particle and its combination with one or more antigens or cells, such as an irradiated cancer cell comprising the one or more antigens. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 18/260741 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/4611 (20230501) A61K 2039/572 (20130101) A61K 2039/55594 (20130101) A61K 2239/59 (20230501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066119 | JEWELL et al. |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher M. JEWELL (Silver Spring, Maryland); James I. ANDORKO (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure relates to methods for eliciting an immune response to a cancer antigen in a subject in need thereof by introducing directly into at least one lymph node of the subject, and preferably at least two lymph nodes, a therapeutically effective amount of a cancer antigen and/or an adjuvant such that an immune response to the cancer antigen is activated or enhanced in the subject. The present disclosure also concerns pharmaceutical compositions that comprise a therapeutically effective amount of a cancer antigen and/or an adjuvant capable of mediating, and more preferably enhancing, activation of the immune system of a subject against cancer cells that are associated with any of a variety of cancers. The disclosure also relates to the use of such pharmaceutical compositions in the treatment or prevention of a cancer in a recipient subject. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 18/261146 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066144 | Pillarsetty et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Naga Vara Kishore Pillarsetty (Jackson Heights, New York); Steven M. Larson (New York, New York); Sang-gyu Lee (New York, New York) |
| ABSTRACT | Described herein are liposome-based nanocarriers that selectively target bone marrow, minimize tumor delivery, and maintain high drug concentrations in bone marrow when compared to conventional systemic delivery. The composition of the liposome-based nanocarriers may also be tuned to selectively target lymph nodes and other reticuloendothelial system organs (e.g., spleen, e.g., livers. Also described herein are methods of imaging and mapping the bone marrow and/or other reticuloendothelial system organs using the described liposome-based nanocarriers. These methods provide high resolution non-invasive and quantitative imaging via PET, which offers advantages over conventional imaging/tracking methods. Furthermore, in certain embodiments, the liposome-based carriers are used to stabilize and deliver radioprotectant/free radical scavenger drugs to the bone marrow, thereby protecting the bone marrow from subsequent radiation exposure, thereby limiting the adverse impact of radiation exposure of the individual. |
| FILED | Monday, March 06, 2023 |
| APPL NO | 18/117531 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/50 (20170801) A61K 47/60 (20170801) A61K 47/547 (20170801) A61K 47/6911 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066147 | Engelhardt et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John F. Engelhardt (Iowa City, Iowa); Ziying Yan (Iowa City, Iowa) |
| ABSTRACT | An isolated recombinant parvovirus vector comprising a synthetic enhancer comprising plurality of enhancer sequences operably linked to a promoter, and methods of using the vector, are provided. |
| FILED | Wednesday, April 26, 2023 |
| APPL NO | 18/139661 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/55 (20170801) A61K 48/0066 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14041 (20130101) C12N 2750/14043 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066148 | Sadelain et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Michel Sadelain (New York, New York); Isabelle Riviere (New York, New York); Jorge Mansilla-Soto (Forest Hills, New York); Xiuyan Wang (New York, New York); George Stamatoyannopoulos (Seattle, Washington); John Stamatoyannopoulos (Seattle, Washington); Mingdong Liu (Seattle, Washington) |
| ABSTRACT | The presently disclosed subject matter provides for expression cassettes that allow for expression of a globin gene or a functional portion thereof, vectors comprising thereof, and cells transduced with such expression cassettes and vectors. The presently disclosed subject matter further provides methods for treating a hemoglobinopathy in a subject comprising administering an effective amount of such transduced cells to the subject. |
| FILED | Thursday, January 26, 2023 |
| APPL NO | 18/160083 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) A61K 48/0066 (20130101) Original (OR) Class Peptides C07K 14/805 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2740/10043 (20130101) C12N 2740/15043 (20130101) C12N 2740/16043 (20130101) C12N 2830/008 (20130101) C12N 2830/15 (20130101) C12N 2830/30 (20130101) C12N 2830/40 (20130101) C12N 2830/46 (20130101) C12N 2830/48 (20130101) C12N 2830/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066156 | Weichert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jamey Weichert (Sun Prairie, Wisconsin); Paul Sondel (Madison, Wisconsin); Anatoly Pinchuk (Fitchburg, Wisconsin); Zachary Morris (Madison, Wisconsin); Mario Otto (Fitchburg, Wisconsin); Bryan Bednarz (Madison, Wisconsin); Peter Carlson (Madison, Wisconsin) |
| ABSTRACT | The disclosed method of treating a malignant solid tumor in a subject includes the steps of administering to the subject an immunomodulatory dose of a radioactive phospholipid metal chelate compound that is differentially retained within malignant solid tumor tissue, and performing in situ tumor vaccination in the subject by introducing into at least one of the malignant solid tumors one or more agents capable of stimulating specific immune cells within the tumor microenvironment, or by performing another method of in situ tumor vaccination. In a non-limiting example, the radioactive phospholipid metal chelate compound has the formula: wherein R1 comprises a chelating agent that is chelated to a metal atom, wherein the metal atom is an alpha, beta or Auger emitting metal isotope with a half life of greater than 6 hours and less than 30 days. In one such embodiment, a is 1, n is 18, m is 0, b is 1, and R2 is —N+(CH3)3. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345385 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/2013 (20130101) A61K 39/39558 (20130101) A61K 51/0408 (20130101) Original (OR) Class A61K 51/0497 (20130101) A61K 2039/545 (20130101) Peptides C07K 16/3084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066185 | Zheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Ying Zheng (Seattle, Washington); Nicole Zeinstra (Seattle, Washington); Ariana Frey (Seattle, Washington) |
| ABSTRACT | Compositions and methods for modular fabrication of large, three-dimensional, perfusable networks of vascularized tissue are provided. Each layer within the tissue may include the same or different cell types and have the same or different types of vasculature. In some aspects layers of tissue together form the large, three-dimensional perfusable networks as each layer contains a portion of the larger tissue and the combination of the various layers creates a tertiary structure of integrated perfusable networks that exhibit remodeling and evenly distributed perfusion among layers while maintaining a patterned open-lumen architecture. |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/458120 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/3804 (20130101) A61L 27/3808 (20130101) Original (OR) Class A61L 27/3826 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 5/0658 (20130101) C12N 2533/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066322 | Pierce, II et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Larry A Pierce, II (Seattle, Washington); Robert S. Miyaoka (Seattle, Washington); Robert L Harrison (Seattle, Washington) |
| ABSTRACT | Various devices, systems, and methods for performing personalized dosimetry of a patient receiving a radiopharmaceutical are described. In an example method, anatomic data is generated by performing a computed tomography (CT) scan on the patient when they are lying down and wearing a garment. Based on the anatomic data, locations of organs of the patient are determined with respect to one or more fiducial markers integrated with the garment. Detectors for detecting photons from a radiopharmaceutical are placed on the garment based on locations of the organs. Subsequently, the patient may be administered a dose of the radiopharmaceutical. When the patient wears the garment, the detectors may detect photons released from the decaying radiopharmaceutical that is distributed in the organs. The radiation dosage to the organs may be determined based on the detected photons. |
| FILED | Friday, November 05, 2021 |
| APPL NO | 18/035612 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/6805 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/0407 (20130101) A61B 6/4266 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1071 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066324 | Alexander et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel A. Alexander (Hanover, New Hampshire); Jacqueline Andreozzi (Hanover, New Hampshire); Petr Bruza (Lebanon, New Hampshire); Rongxiao Zhang (Lebanon, New Hampshire); David J. Gladstone (Lebanon, New Hampshire) |
| ABSTRACT | A system includes a cylindrical phantom and a conical structure disposed in the phantom. The conical structure is shaped as a frustum and emits Cherenkov radiation when exposed to ionizing radiation. The system can be used for calibration of an MR-Linac system by exposing the system to ionizing radiation. The Cherenkov radiation can be imaged during exposure to ionizing radiation. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 18/280289 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1075 (20130101) Original (OR) Class A61N 2005/1055 (20130101) A61N 2005/1076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066509 | Nagorny et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pavel Nagorny (Ann Arbor, Michigan); Iaroslav Khomutnyk (Ann Arbor, Michigan); Sibin Wang (Ann Arbor, Michigan); Oleksii Zhelavskyi (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are immobilized chiral phosphoric acids and methods of using immobilized chiral phosphoric acids as catalysts for protecting group reactions. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/232230 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/06 (20130101) B01J 31/0258 (20130101) Original (OR) Class B01J 35/026 (20130101) B01J 37/0219 (20130101) B01J 37/0221 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 51/00 (20130101) Heterocyclic Compounds C07D 309/10 (20130101) C07D 309/30 (20130101) C07D 493/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066689 | Moghadam |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KENNESAW STATE UNIVERSITY RESEARCH AND SERVICE FOUNDATION, INC. (KENNESAW, Georgia) |
| ASSIGNEE(S) | KENNESAW STATE UNIVERSITY RESEARCH AND SERVICE FOUNDATION, INC. (KENNESAW, Georgia) |
| INVENTOR(S) | Amir Ali Amiri Moghadam (Marietta, Georgia) |
| ABSTRACT | An apparatus is described for robotic control of an ultrasound imaging device. The apparatus comprises a fixed base and a movable platform with an end-effector. A plurality of passive soft links connects the platform to the base. A series of cables connect the platform to a set of motors adjacent the base. When the platform is at rest, the tension in the cables counter-balances the passive soft links pushing the platform away from the base plate. Control electronics move the motors so as to control the location and the orientation of the platform. By increasing or decreasing tension in the cables, the motors smoothly control the location and the orientation of the platform and thus the end effector. Such a robotic apparatus can be used to provide expert handling of an ultrasound imaging device remotely. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/459205 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0012 (20130101) B25J 9/0015 (20130101) B25J 9/1075 (20130101) B25J 9/1623 (20130101) Original (OR) Class B25J 9/1664 (20130101) B25J 13/065 (20130101) B25J 15/0019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067523 | Hall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Third Pole, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Third Pole, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Gregory W. Hall (Belmont, Massachusetts); Nathaniel G. Jackson (Lexington, Massachusetts); Benjamin J. Apollonio (Lunenburg, Massachusetts) |
| ABSTRACT | Architectures for production of nitric oxide (NO) include systems and methods for generating NO having one or more plasma chambers configured to ionize a reactant gas to generate a plasma for producing a product gas containing NO using a flow of the reactant gas through one or more plasma chambers; a controller configured to regulate the amount of nitric oxide in the product gas using one or more parameters as an input to the controller, one or more parameters including information from a plurality of sensors configured to collect information relating to at least one of the reactant gas, the product gas, and a medical gas into which product gas flows; and a flow divider configured to divide a product gas flow from the plasma chamber into a first product gas flow to provide a variable flow to a patient inspiratory flow and a second product gas flow. |
| FILED | Thursday, November 02, 2023 |
| APPL NO | 18/500770 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/24 (20130101) Original (OR) Class C01B 21/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067600 | ROY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas); Oregon Health and Science University (Portland, Kansas) |
| ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas); Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Sudeshna ROY (Lawrence, Kansas); Paolo BERNARDI (Padova, Italy); Michael FORTE (Portland, Oregon); Frank SCHOENEN (Lawrence, Kansas); Justina SILEIKYTE (Padova, Italy) |
| ABSTRACT | The present technology relates to compounds of any one of Formula I, II, IIa, III, IV, and/or V as described herein and their tautomers and/or pharmaceutically acceptable salts, compositions, and methods of uses thereof. |
| FILED | Thursday, March 16, 2023 |
| APPL NO | 18/122605 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/415 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) A61P 25/00 (20180101) Acyclic or Carbocyclic Compounds C07C 235/38 (20130101) C07C 235/42 (20130101) Original (OR) Class C07C 235/56 (20130101) Heterocyclic Compounds C07D 203/04 (20130101) C07D 211/14 (20130101) C07D 231/14 (20130101) C07D 261/18 (20130101) C07D 295/135 (20130101) C07D 295/185 (20130101) C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067603 | POTTER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (MINNEAPOLIS, Minnesota); ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David A. POTTER (MINNEAPOLIS, Minnesota); Zhijun GUO (MINNEAPOLIS, Minnesota); Gunda GEORG (MINNEAPOLIS, Minnesota); Kwon Ho HONG (MINNEAPOLIS, Minnesota); Jianxun LEI (MINNEAPOLIS, Minnesota); Elizabeth AMBROSE (MINNEAPOLIS, Minnesota); Kris WHITE (New York, New York) |
| ABSTRACT | Biguanide compounds of formula where R1 comprises a cubanyl-substituted alkyl and R2 comprises a substituted or unsubstituted alkyl, and their use in the treatment of cancers and viral infections are described. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/258076 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Acyclic or Carbocyclic Compounds C07C 279/26 (20130101) Original (OR) Class C07C 2603/90 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067621 | WEAVER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jimmie D. WEAVER (Stillwater, Oklahoma); Jon DAY (Stillwater, Oklahoma); Sascha GROTJAHN (Regensburg, Germany); Sameera SENAWEERA (Minneapolis, Minnesota); Burkhard KOENIG (Regensburg, Germany); The Board of Regents For The Oklahoma Agricultural And Mechanical Colleges (Stillwater, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jimmie D. WEAVER (Stillwater, Oklahoma); Jon DAY (Stillwater, Oklahoma); Sascha GROTJAHN (Regensburg, Germany); Sameera SENAWEERA (Minneapolis, Minnesota); Burkhard KOENIG (Regensburg, Germany) |
| ABSTRACT | Polyfluorinated compounds are disclosed, including polyfluorinated cannabinoid and cannabinoid-like compounds. Also disclosed are methods of producing the polyfluorinated compounds. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 18/547251 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 33/46 (20130101) C07C 69/78 (20130101) Heterocyclic Compounds C07D 311/80 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067625 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Damian Winston Young (Houston, Texas); Mirjana Maletic-Savatic (Houston, Texas); Prasanna Kandel (Houston, Texas); Fatih Semerci (Houston, Texas); Srinivas Chamakuri (Houston, Texas) |
| ABSTRACT | Small molecules acting through the ligand binding domain of nuclear receptor TLX (NR2E1) are disclosed, as well as the use thereof for promoting neurogenesis and treating disorders associated with nuclear receptor TLX, including neurological disorders such as Alzheimer's disease. In certain embodiments, the invention provides compounds according to Formula II as described herein, and pharmaceutically acceptable salts or isomers thereof. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 18/268753 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Heterocyclic Compounds C07D 241/04 (20130101) C07D 401/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067634 | Sherman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David H. Sherman (Ann Arbor, Michigan); Morgan T. McCauley (Ann Arbor, Michigan); Nolan Carney (Ann Arbor, Michigan); Andrew W. Robertson (Ann Arbor, Michigan); Mark M. Painter (Ann Arbor, Michigan); Kathleen L. Collins (Ann Arbor, Michigan); Ashootosh Tripathi (Ypsilanti, Michigan); Alanna R. Condren (Ann Arbor, Michigan) |
| ABSTRACT | This disclosure relates generally to inhibitors of MHC-I downmodulation, and methods of treating or preventing an HIV infection by administering the inhibitors to a patient in need of treatment thereof. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/266688 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Heterocyclic Compounds C07D 407/06 (20130101) Original (OR) Class C07D 407/14 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 17/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067639 | Disney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EXPANSION THERAPEUTICS, INC. (San Diego, California); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATION (Gainesville, Florida) |
| INVENTOR(S) | Matthew Disney (Jupiter, Florida); Timothy Allen Blizzard (Princeton, New Jersey); Ippei Usui (Jupiter, Florida) |
| ABSTRACT | Disclosed herein are compounds that selectively bind an expanded transcribed repeat r(G4C2)exp, prevent sequestration of RNA-binding proteins, and inhibit translation of repeat associated non-ATG (RAN) translation responsible for generation of toxic dipeptide repeats underlying diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The compounds and their pharmaceutical compositions are useful in treating a disease or condition characterized by an expanded G4C2 repeat RNA (r(G4C2)exp), such as ALS and FTD. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 18/044260 |
| CURRENT CPC | Heterocyclic Compounds C07D 403/12 (20130101) C07D 471/04 (20130101) Original (OR) Class C07D 491/048 (20130101) C07D 495/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067685 | de la Fuente-Nunez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | César de la Fuente-Nunez (Philadelphia, Pennsylvania); Angela Arciello (Portici, Italy); Angela Cesaro (Philadelphia, Pennsylvania); Marcelo Der Torossian Torres (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided herein are antimicrobial peptides, as well as methods of treating a microbial infection, methods of treating inflammation, and methods of reducing biofilm formation, using the disclosed antimicrobial peptides. |
| FILED | Thursday, June 08, 2023 |
| APPL NO | 18/331331 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 14/4747 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067713 | SHETTY |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Sreerama SHETTY (Tyler, Texas) |
| ABSTRACT | Methods for treating, reducing, ameliorating or inhibiting symptoms idiopathic pulmonary fibrosis (IPF) or interstitial pneumonia, comprising administering to a subject in need of an effective amount of a) multiple EGF-like-domains-9 (MEGF9) or a biologically active fragment thereof; b) uncoordinated receptor 5A (UNC5A) or a biologically active fragment thereof; c) dolichyl-phosphate beta-glucosyltransferase (ALG5) or a biologically active fragment thereof; d) a combination of two or three of a)-c); e) an antibody specifically binding to a); f) an antibody specifically binding to b); g) an antibody specifically binding to c); h) a combination of two or three of e)-g); or i) a combination of at least one of a)-c) and at least one of e)-g). Pharmaceutical compositions and processes for making and using the compositions are also disclosed. |
| FILED | Thursday, October 05, 2023 |
| APPL NO | 18/481529 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Peptides C07K 14/47 (20130101) C07K 16/22 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 16/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067717 | Bharat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Ankit Bharat (Evanston, Illinois); Emilia Lecuona (Evanston, Illinois); Wenbin Yang (Evanston, Illinois) |
| ABSTRACT | Provided herein are methods of preventing or reducing the incidence of primary graft dysfunction in a subject. |
| FILED | Wednesday, August 30, 2023 |
| APPL NO | 18/240201 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/2006 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Peptides C07K 16/245 (20130101) Original (OR) Class C07K 2317/21 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/689 (20130101) G01N 2333/545 (20130101) G01N 2800/50 (20130101) G01N 2800/245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067724 | Schneider et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LENTIGEN TECHNOLOGY, INC. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dina Schneider (Potomac, Maryland); Rimas J. Orentas (Seattle, Washington); Boro Dropulic (Ellicott City, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
| ABSTRACT | Chimeric antigen receptors containing human CD19 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed. |
| FILED | Wednesday, June 07, 2023 |
| APPL NO | 18/330587 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 39/001112 (20180801) A61K 2035/124 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70596 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 2317/73 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/035 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067733 | Cheresh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Cheresh (La Jolla, California); Hiromi Wettersten (La Jolla, California) |
| ABSTRACT | Provided are compositions and methods for treating or ameliorating a cancer by targeting cell surface-expressed αvβ3 (avb3) polypeptides in Cancer Stem Cells (CSCs) to kill the CSCs, thus treating ameliorating or slowing the development of cancers caused or initiated by or sustained by cancer or tumor cells, or Cancer Stem Cells (CSCs), expressing αvβ3 polypeptides on their cell surfaces. Provided are compositions and methods for targeting and killing αvβ3-positive Cancer Stem Cells (CSCs) and treating drug resistant cancers. In alternative embodiments, compositions and methods as provided herein use an antibody that can specifically bind to human αvβ3 that also comprises an Fc portion that can mediate antibody-dependent un-mediated cytotoxicity (ADCC) killing of cancer or tumor cells by macrophages; for example, use a humanized antibody to αvβ3 that has been modified to include an engineered Fc portion that specifically binds to human macrophages. |
| FILED | Wednesday, October 04, 2023 |
| APPL NO | 18/480778 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2848 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067756 | Spiegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); Ryan Murelli (Belleville, New Jersey); Andrew Zhang (Waltham, Massachusetts) |
| ABSTRACT | The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule. |
| FILED | Wednesday, June 07, 2023 |
| APPL NO | 18/206937 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/4192 (20130101) A61K 45/06 (20130101) A61K 47/54 (20170801) A61K 47/55 (20170801) A61K 47/68 (20170801) A61K 47/549 (20170801) A61K 47/646 (20170801) A61K 47/6803 (20170801) A61K 47/6869 (20170801) A61K 47/6873 (20170801) A61K 47/6891 (20170801) Heterocyclic Compounds C07D 249/04 (20130101) Peptides C07K 16/44 (20130101) Original (OR) Class C07K 16/3069 (20130101) C07K 2317/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067767 | APPEL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric A. APPEL (Palo Alto, California); Caitlin MAIKAWA (Boston, Massachusetts); Joseph L. Mann (Mountain View, California) |
| ABSTRACT | A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes. |
| FILED | Tuesday, October 17, 2023 |
| APPL NO | 18/381125 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 9/5146 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067910 | Sevenler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Derin Sevenler (Charlestown, Massachusetts); Mehmet Toner (Charlestown, Massachusetts) |
| ABSTRACT | Provided herein are methods of intracellular delivery of a substance to one or more cells. The methods include providing a substrate defining a micro-channel in fluid communication with a first chamber and optionally in fluid communication with a second chamber, the micro-channel having a hydraulic diameter that is less than a hydraulic diameter of the first and second chambers; and driving a cell suspension through the micro-channel, thereby: i) causing the one or more cells to be stretched along a direction of flow and ii) inducing a formation of one or more temporary pores in a membrane of the one or more cells, wherein the cell suspension comprises the one or more cells, a polymer, and the substance. Also provided are systems for the intracellular delivery of a substance to one or more cells. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 18/271826 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class C12M 35/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 15/87 (20130101) C12N 15/1138 (20130101) C12N 2521/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067924 | Chambers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Stuart Chambers (San Francisco, California); Lorenz Studer (New York, New York); Zehra Dincer (New York, New York); Bastian Zimmer (Hamburg, Germany) |
| ABSTRACT | Cranial placodes are embryonic structures essential for sensory and endocrine organ development. The efficient derivation of cranial placodes from human pluripotent stem cells is disclosed where the timed removal of the BMP inhibitor Noggin, a component of the dual-SMAD inhibition strategy of neural induction, triggers placode induction at the expense of CNS fates. Further fate specification at the pre-placode stage enables the selective generation of placode-derived trigeminal ganglia capable of in vivo engraftment, mature lens fibers and anterior pituitary hormone-producing cells that upon transplantation produce hormones including, but not limited to, human growth hormone and adrenocortiocotropic hormone in vivo. Alternatively, anterior pituitary hormone-producing cells are generated in cell culture systems in vitro. |
| FILED | Wednesday, December 21, 2022 |
| APPL NO | 18/069299 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) Heterocyclic Compounds C07D 211/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067926 | Siprashvili et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States Government as represented by the Department of Veterans Affairs (Washington, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zurab Siprashvili (San Mateo, California); Ngon T. Nguyen (Union City, California); M. Peter Marinkovich (Redwood City, California); Jean Tang (Stanford, California); Alfred T. Lane (Los Altos, California); Paul A. Khavari (Palo Alto, California) |
| ABSTRACT | Methods are provided for the cell-based delivery of collagen VII for the treatment of Epidermolysis Bullosa and corneal erosion. The disclosure also provides a composition and a pharmaceutical composition comprises, comprise, or alternatively consist essentially of, or yet further consist of a keratinocyte sheet or a corneal cell sheet. |
| FILED | Friday, November 03, 2023 |
| APPL NO | 18/501837 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) A61K 48/0075 (20130101) A61K 48/0091 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0629 (20130101) Original (OR) Class C12N 2510/00 (20130101) C12N 2760/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067927 | Sentman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (HANOVER, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles L. Sentman (Grantham, New Hampshire) |
| ABSTRACT | The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same. |
| FILED | Monday, October 23, 2023 |
| APPL NO | 18/492221 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/585 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/515 (20130101) C12N 2511/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067928 | Sentman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (HANOVER, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles L. Sentman (Grantham, New Hampshire) |
| ABSTRACT | The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same. |
| FILED | Monday, October 23, 2023 |
| APPL NO | 18/492310 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/585 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/515 (20130101) C12N 2511/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067945 | Colecraft et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Henry M. Colecraft (Robbinsville, New Jersey); Scott Kanner (New York, New York) |
| ABSTRACT | The present disclosure provides, inter alia, a recombinant engineered deubiquitinase (DUB) and methods for treating or ameliorating an inherited ion channelopathy, such as long QT syndrome, Brugada syndrome, or cystic fibrosis, in a subject. Further provided are methods for screening mutations causing such inherited ion channelopathies for a trafficking-deficient mutation that is treatable by the recombinant engineered DUB disclosed herein. |
| FILED | Friday, November 03, 2023 |
| APPL NO | 18/501966 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6472 (20130101) Original (OR) Class C12N 15/85 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Enzymes C12Y 304/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067946 | Colecraft et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Henry M. Colecraft (Robbinsville, New Jersey); Scott Kanner (New York, New York) |
| ABSTRACT | The present disclosure provides, inter alia, a recombinant engineered deubiquitinase (DUB) and methods for treating or ameliorating an inherited ion channelopathy, such as long QT syndrome, Brugada syndrome, or cystic fibrosis, in a subject. Further provided are methods for screening mutations causing such inherited ion channelopathies for a trafficking-deficient mutation that is treatable by the recombinant engineered DUB disclosed herein. |
| FILED | Friday, November 03, 2023 |
| APPL NO | 18/501967 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6472 (20130101) Original (OR) Class C12N 15/85 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Enzymes C12Y 304/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067947 | Kohane et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Servic (Silver Spring, Maryland) |
| ASSIGNEE(S) | Children's Medical Center Corporation (BOSTON, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Servic (SILVER SPRING, Maryland) |
| INVENTOR(S) | Daniel S. Kohane (Newton, Massachusetts); Juan C. Ibla (Medfield, Massachusetts); Upendra Katneni (Clarksburg, Maryland); Chava Kimchi-Sarfaty (North Potomac, Maryland) |
| ABSTRACT | Provided herein are polypeptides that are truncated modified recombinant forms of ADAMTS13, nucleic acid molecules encoding the polypeptides, drug delivery compositions and pharmaceutical compositions comprising the polypeptides, and methods of using the polypeptides and compositions (e.g., in the treatment of thrombotic thrombocytopenic purpura (TTP)). |
| FILED | Thursday, October 28, 2021 |
| APPL NO | 18/034136 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 38/4886 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6489 (20130101) Original (OR) Class Enzymes C12Y 304/24087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067948 | Kohli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Rahul Kohli (Penn Valley, Pennsylvania); Emily Schutsky (Waltham, Massachusetts); Monica Yun Liu (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention includes mutant AID, APOBEC, and Tet enzymes with improved functions. In one aspect the invention provides APOBEC fusion proteins comprising hyperactive deamination activity. In another aspect, the invention provides AID mutant proteins comprising hyperactive deamination activity. In yet another aspect, the invention provides mutant Tet proteins capable of stalling oxidation at a 5-hydroxymethylcytosine (hmC). |
| FILED | Wednesday, April 05, 2023 |
| APPL NO | 18/296061 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) C12N 9/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067949 | CALDWELL |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); The US Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); The US Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Ruth CALDWELL (Augusta, Georgia) |
| ABSTRACT | Pathological retinal neovascularization is a common micro-vascular complication in several retinal diseases including retinopathy of prematurity (ROP), diabetic retinopathy, age related macular degeneration and central vein occlusion. Disclosed herein are compositions and methods useful for the treatment or prevention of retinal neovascularization and related diseases in a subject in need thereof. Exemplary methods include administering a composition including PEGylated arginase 1 to a subject in need thereof to promote reparative angiogenesis and decrease retinal neovascularization in the eye. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/350668 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067952 | Spiegel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David A. Spiegel (New Haven, Connecticut); Charles E. Jakobsche (Worcester, Massachusetts) |
| ABSTRACT | The present invention relates to chimeric (preferably, bifunctional) compounds, compositions comprising those compounds and methods of treating cancer in a patient or subject, especially including metastatic cancer where cancer cells exhibit overexpression (heightened expression) of cell surface urokinase-type plasminogen activator receptor (urokinase receptor) compared to normal (non-cancerous) cells. The compounds preferably covalently bind to the urokinase receptor and recruit native antibodies of the patient or subject where the antibodies can selectively degrade and/or deactivate targeted cancer cells through antibody-dependent cellular phagocytosis and/or antibody-dependent cellular cytotoxicity (ADCC) against a large number and variety of cancers, thus providing cancer cell death and/or an inhibition of growth, elaboration and/or metastasis of the cancer, including remission and cure of the patient's cancer. |
| FILED | Thursday, September 07, 2023 |
| APPL NO | 18/243169 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/165 (20130101) A61K 31/352 (20130101) A61K 31/365 (20130101) A61K 38/05 (20130101) A61K 38/482 (20130101) A61K 45/06 (20130101) A61K 47/54 (20170801) A61K 47/60 (20170801) Acyclic or Carbocyclic Compounds C07C 279/12 (20130101) Heterocyclic Compounds C07D 491/107 (20130101) C07D 493/10 (20130101) Peptides C07K 5/06026 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067956 | Tamburini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Beth A. Jiron Tamburini (Denver, Colorado); Jay R. Hesselberth (Denver, Colorado); Shannon Marie Walsh (East Lansing, Michigan) |
| ABSTRACT | The present invention relates to a molecular tracking device to follow distribution, acquisition, and retention of antigens in cells, such as in the lymphatic system of a subject. Molecular conjugates including an antigen conjugated to a nuclease-resistant tag are tracked using single-cell mRNA sequencing. The molecular tracking devices allow new approaches to investigate dynamic tissue dissemination of antigens and identify new mechanisms of antigen acquisition and retention at cellular resolution in vivo. |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 18/271727 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6841 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067957 | Collins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | James J. Collins (Newton, Massachusetts); Raphael Gayet (Cambridge, Massachusetts); Katherine IIia (Melrose, Massachusetts); Shiva Razavi (Cambridge, Massachusetts); Nathaniel Tippens (Cambridge, Massachusetts); Kehan Zhang (Brighton, Massachusetts); Jack Chen (Newton, Massachusetts); Jonathan Chen (Boston, Massachusetts); Makoto Lalwani (San Jose, California) |
| ABSTRACT | Genetic circuits that control transgene expression in response to pre-defined transcriptional cues would enable the development of smart therapeutics. The present disclosure relates to engineered programmable single-transcript RNA sensors in which adenosine deaminases acting on RNA (ADARs) autocatalytically convert trigger hybridization into a translational output. This system amplifies the signal from editing by endogenous ADAR through a positive feedback loop. Amplification is mediated by the expression of a hyperactive, minimal ADAR variant and its recruitment to the edit site via an orthogonal RNA targeting mechanism. This topology confers high dynamic range, low background, minimal off-target effects, and a small genetic footprint. The circuits and systems disclosed herein leverage an ability to detect single nucleotide polymorphisms and modulate translation in response to endogenous transcript levels in mammalian cells. |
| FILED | Thursday, June 22, 2023 |
| APPL NO | 18/339607 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/78 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 15/1082 (20130101) Original (OR) Class C12N 15/1086 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 305/04004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067963 | Brar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jaan Biotherapeutics LLC (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bhawanjit Kaur Brar (La Jolla, California); Eric G. Marcusson (San Francisco, California) |
| ABSTRACT | Disclosed herein include microRNA antagonists, therapeutic compositions that include one or more of such microRNA antagonists, and methods of treating and/or ameliorating cardiac diseases and/or muscular dystrophy disorders with the microRNA antagonists. Also included are combination therapies, wherein a therapeutic composition disclosed herein and an additional therapy agent are provided to a subject having or suspected of having cardiac disease and/or muscular dystrophy disorder. In particular, some embodiments disclosed herein relate to compositions and methods for transiently administering a mixture of microRNA antagonists for promoting cardiomyocyte proliferation and cardiac regeneration. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/160998 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/141 (20130101) C12N 2310/315 (20130101) C12N 2310/344 (20130101) C12N 2310/346 (20130101) C12N 2310/3231 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067967 | Khvorova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Vignesh Narayan Hariharan (Natick, Massachusetts); Sarah Davis (Wellesley, Massachusetts); Annabelle Biscans (Cambridge, Massachusetts); Ananth Karumanchi (Chestnut Hill, Massachusetts) |
| ABSTRACT | This disclosure relates to novel targets for angiogenic disorders. Novel oligonucleotides are also provided. Methods of using the novel oligonucleotides for the treatment of angiogenic disorders (e.g., preeclampsia) are also provided. |
| FILED | Tuesday, May 23, 2023 |
| APPL NO | 18/321971 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/12 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/312 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067970 | Jaiswal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The Regents of the University of Michigan (Ann Arbor, Michigan); Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siddhartha Jaiswal (San Francisco, California); Alexander Bick (Redwood City, California); Joshua Weinstock (Redwood City, California) |
| ABSTRACT | Compositions and methods are provided for the analysis and treatment of conditions relating to clonal hematopoiesis of indeterminate potential (CHIP). In some embodiments, treatment is provided to reduce the progression of CHIP, particularly to reduce the progression to hematologic malignancy and/or heart disease. In other embodiments, methods are provided for determining clonal expansion, for example as a molecular diagnostic test that enables determination of clonal growth rate from a single sample. The method for determining clonal expansion can be applied to identify factors that influence clonal expansion, including environmental, metabolic, microbiome, and genetic. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 18/271417 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 38/465 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Original (OR) Class C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067988 | Asokan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Aravind Asokan (Durham, North Carolina); Trevor Gonzalez (Durham, North Carolina); Lawrence Patrick Havlik (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides adeno-associated virus (AAV) vectors, comprising coevolved capsid variant proteins, pharmaceutical compositions, methods of making, and methods for delivering such to a subject. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/474506 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068008 | Haake et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MicrobeDX Inc. (Novato, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David A. Haake (Culver City, California); Daniel Gussin (Encinitas, California); Gabriel K. Monti (Cypress, California); Bernard M. Churchill (Los Angeles, California); Colin W. Halford (Los Angeles, California) |
| ABSTRACT | The present invention relates generally to materials and methods for detection of bacteria, and for testing and determination of antibiotic susceptibility of bacteria in specimens of bodily fluid and other samples. The invention also relates to materials and methods for monitoring the physiological response of bacteria to antimicrobial agents, and for reducing background and increasing sensitivity of assays that involve the detection and/or measurement of RNA, such as rRNA. The invention provides kits comprising an RNase packaged for use in the methods described herein. |
| FILED | Monday, August 21, 2023 |
| APPL NO | 18/452765 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) C12Q 1/44 (20130101) Original (OR) Class C12Q 1/689 (20130101) C12Q 1/6813 (20130101) C12Q 1/6895 (20130101) C12Q 2521/327 (20130101) C12Q 2600/106 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/922 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068023 | Sadhasivam |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Senthilkumar Sadhasivam (Bloomington, Indiana) |
| ABSTRACT | A method for controlling pain in a patient in need thereof includes administering to the patient multiple low doses of methadone, wherein each subsequent dose of methadone is administered within an effective period of time from a previously administered dose of methadone, and wherein the patient has no respiratory depression and no QT prolongation. A method for providing personalized analgesic therapy to a surgical patient includes directing preoperative genotyping of a patient to determine what allele is present at a gene locus to obtain a patient-specific genetic data set, wherein the gene locus is one or more of a locus that encodes an enzyme or protein or transporter or receptor associated with methadone metabolism and responses; producing a prediction of the patient's response to perioperative methadone administration based on the data set; and making a determination whether to administer methadone and a precision perioperative dosing regimen. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 18/261451 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068033 | Markowitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sanford Markowitz (Pepper Pike, Ohio); Amitabh Chak (University Heights, Ohio); Helen Moinova (Cleveland, Ohio); Joseph Willis (Shaker Heights, Ohio); Bert Vogelstein (Baltimore, Maryland); Kenneth Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Baltimore, Maryland); Chetan Bettewgowda (Baltimore, Maryland); Christopher Douville (Baltimore, Maryland) |
| ABSTRACT | A method of detecting Barrett's esophagus with low grade dysplasia, or Barrett's esophagus with high grade dysplasia, or adenocarcinoma of the esophagus, applying a Repetitive Element Aneuploidy Sequencing System (RealSeqS) methodology to a biological sample from the esophagus of the subject to detect Barrett's esophagus with low grade dysplasia, or Barrett's esophagus with high grade dysplasia, or adenocarcinoma of the esophagus. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 18/261366 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068037 | Gioeli |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel G. Gioeli (Charlottesville, Virginia) |
| ABSTRACT | Provided herein is a previously unannotated IncRNA lying within exon six and 3′UTR of the LCK gene, labeled “HULLK” for Hormone-Upregulated IncRNA within LCK. HULLK is a novel IncRNA situated within the LCKgene that can serve as an oncogene in PCa. Accordingly, provided are methods and compositions for diagnosing and treating prostate cancer based on HULLK that regulates prostate cancer cell growth. |
| FILED | Thursday, November 11, 2021 |
| APPL NO | 18/036610 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068042 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Edison T. Liu (Bar Harbor, Maine); Francesca Menghi (Bar Harbor, Maine) |
| ABSTRACT | Provided herein, in some embodiments, are novel methods for predicting response to a platinum-based chemotherapeutic agent in triple negative breast cancer and ovarian carcinoma. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 18/272260 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068045 | Markowitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sanford D. Markowitz (Pepper Pike, Ohio); Joseph E. Willis (Shaker Heights, Ohio); Helen Moinova (Beachwood, Ohio); Thomas LaFramboise (Shaker Heights, Ohio); Omar de la Cruz Cabrera (Chagrin Falls, Ohio); Amitabh Chak (University Heights, Ohio) |
| ABSTRACT | The disclosure provides methods for identifying genomic loci that are differentially methylated in neoplastic cancers, e.g., esophageal cancers. Identification of methylated genomic loci, and optionally in combination with the identification of somatic mutations in TP53, has numerous uses, including for example, to characterize disease risk, to predict responsiveness to therapy, to non-invasively diagnose subjects and to treat subjects determined to have gastrointestinal neoplasias. |
| FILED | Thursday, October 19, 2023 |
| APPL NO | 18/381926 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6837 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/154 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068047 | CHATTOPADHYAY et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Houston, Texas) |
| INVENTOR(S) | Chandrani CHATTOPADHYAY (Houston, Texas); Janos ROSZIK (Houston, Texas) |
| ABSTRACT | Provided herein are methods for identifying expression of SDHA, MIF, and or monosomy 3 or disomy 3 status in sample to identify the sample as high-risk melanoma and/or the sensitivity to oxidative phosphorylation inhibitors. Also provided herein are methods for treating monosomy 3 uveal melanoma by administering a SDHA inhibitor in combination with an oxidative phosphorylation inhibitor. |
| FILED | Thursday, September 07, 2023 |
| APPL NO | 18/463282 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 103/05001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068050 | Singer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HelixBind, Inc. (Boxborough, Massachusetts) |
| ASSIGNEE(S) | HelixBind, Inc. (Boxborough, Massachusetts) |
| INVENTOR(S) | Alon Singer (Concord, Massachusetts); Ranjit Prakash (Northborough, Massachusetts); Jork Nolling (Hopedale, Massachusetts) |
| ABSTRACT | The present disclosure generally relates to the field of microbial pathogen detection and identification utilizing genomic sequence recognition. |
| FILED | Tuesday, October 17, 2023 |
| APPL NO | 18/488632 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6895 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068057 | Shalek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander K. Shalek (Cambridge, Massachusetts); Carly Ziegler (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments disclosed herein provide a pan-tissue cell atlas of healthy and diseased subjects obtained by single cell sequencing. The present invention discloses novel markers for cell types. Moreover, genes associated with disease, including HIV infection and tuberculosis are identified. The invention provides for diagnostic assays based on gene markers and cell composition, as well as therapeutic targets for controlling immune regulations and cell-cell communication of the cell types disclosed herein. In addition, novel cell types and methods of quantitating, detecting and isolating the cell types are disclosed. |
| FILED | Monday, August 21, 2023 |
| APPL NO | 18/452789 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068797 | Canales Benavides et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arturo Alejandro Canales Benavides (Rochester, New York); Paul Scott Carney (Washington, District of Columbia); James Matthew Zavislan (Canaandaigua, New York) |
| ABSTRACT | A scanning imaging method includes splitting an optical beam into a reference beam and a scanning beam, generating an interference map, and processing the interference map to produce a reconstructed image of a sample. Generating the interference map includes, for each of a plurality of sections of the sample, generating a respective interference-map element of the interference map by: (i) illuminating the section with the scanning beam to generate a plurality of scattered beams, each scattered beam corresponding to a respective spatial frequency of the scanning beam, (ii) attenuating the reference beam, (iii) generating a plurality of interference signals at least in part by interferometrically combining the plurality of scattered beams and the attenuated reference beam while modulating a phase difference between the reference beam and the plurality of scattered beams, and (iv) detecting the plurality of interference signals to yield the respective interference-map element. |
| FILED | Tuesday, August 23, 2022 |
| APPL NO | 17/821613 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02042 (20130101) Original (OR) Class G01B 9/02091 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0056 (20130101) Information Storage Based on Relative Movement Between Record Carrier and Transducer G11B 7/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068803 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New Jersey Institute of Technology (Newawrk, New Jersey) |
| ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| INVENTOR(S) | Xuan Liu (Berkeley Heights, New Jersey); Yuwei Liu (Harrison, New Jersey); Yuanwei Zhang (New Providence, New Jersey); Zhaoxiong Wan (Newark, New Jersey) |
| ABSTRACT | Optically computed phase imaging systems and methods are provided. An example system includes an interferometer configured to output 3D spatial-spectral data of a sample including an interferometric signal and an optical computation assembly having a spatial light modulator configured to modulate the 3D spatial-spectral data with a modulation pattern. The modulation pattern modulates the interferometric signal along a spectral dimension to select a depth to obtain a sample signal at the selected depth and modulates the interferometric signal along a first spatial dimension to create a waveform to facilitate phase extraction. The system further includes a detector configured to detect 2D spatial data of the sample. The system further includes a processor coupled to a memory, the processor configured to process the 2D spatial data to extract phase information of the sample. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984726 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/2441 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0056 (20130101) G02B 21/364 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068965 | ROS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandra ROS (Phoenix, Arizona); Daihyun KIM (Mesa, Arizona); Austin ECHELMEIER (Tempe, Arizona); Jorvani CRUZ VILLARREAL (Tempe, Arizona); Ana EGATZ-GOMEZ (Phoenix, Arizona); Sebastian QUINTANA (Phoenix, Arizona) |
| ABSTRACT | Methods and systems are provided for serial femtosecond crystallography for reducing the vast amount of waste of injected crystals practiced with traditional continuous flow injections. A micrometer-scale 3-D printed water-in-oil droplet generator device includes an oil phase inlet channel, an aqueous phase inlet channel, a droplet flow outlet channel, and two embedded non-contact electrodes. The inlet and outlet channels are connected internally at a junction. The electrodes comprise gallium metal injected within the 3-D printed device. Voltage across the electrodes generates water-in-oil droplets, determines a rate for a series of droplets, or triggers a phase shift in the droplets. An external trigger generates the droplets based on the frequency of an XFEL utilized in droplet detection, thereby synchronizing a series of droplets with x-ray pulses for efficient crystal detection. The generated droplets can be coupled to an SFX with XFEL experiment compatible with common liquid injector such as a GDVN. |
| FILED | Tuesday, November 07, 2023 |
| APPL NO | 18/504091 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0241 (20130101) B01L 3/50273 (20130101) B01L 2300/0867 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20025 (20130101) Original (OR) Class G01N 2223/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069001 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Silver Spring, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Silver Spring, Maryland) |
| INVENTOR(S) | Xiaoming Xu (Columbia, Maryland); Deval Patel (Frederick, Maryland); Ying Zhang (Centreville, Virginia) |
| ABSTRACT | An in vitro release test (IVRT) method and system is provided for drug release testing. The IVRT method, referred to herein as adaptive perfusion, employ tangential-flow filtration (TFF), where released drug products that are smaller than a molecular weight cutoff (MWCO) of a membrane filter pass therethrough into the permeate. Unreleased drug products are retained by the pores of the filter and are recirculated to a retentate reservoir. Fresh media is provided to the retentate in order to maintain a constant total volume for the sample as well as to maintain sink conditions for the drug release. Drug concentration in the retentate and permeate are evaluated by in situ monitoring with one or more sensors and/or by periodic removal of aliquots from the respective reservoirs. In some embodiments, the membrane filter can be conditioned prior to use in order to improve the accuracy, precision, or both of the subsequent testing. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 18/268158 |
| CURRENT CPC | Separation B01D 15/08 (20130101) B01D 61/14 (20130101) B01D 63/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/14 (20130101) G01N 30/74 (20130101) G01N 33/15 (20130101) Original (OR) Class G01N 2030/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069032 | Chiu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington); Clemson University Research Foundation (Clemson, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel T. Chiu (Seattle, Washington); Changfeng Wu (Changchun, China PRC); Jason McNeil (Clemson, South Carolina); Jiangbo Yu (Bothell, Washington) |
| ABSTRACT | The present invention provides, among other aspects, functionalized chromophoric polymer dots comprising a hydrophobic core and a hydrophilic cap, and bioconjugates thereof. Also provided are improved methods for preparing functionalized chromophoric polymer dots. Methods for in vivo imaging and molecular labeling are also disclosed. |
| FILED | Monday, October 23, 2023 |
| APPL NO | 18/492120 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/587 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069039 | Ranum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Laura Ranum (Gainesville, Florida); Monica Banez Coronel (Gainesville, Florida) |
| ABSTRACT | Aspects of the disclosure relate to methods and compositions (e.g., kits) for detecting certain repeat-associated non-ATG (RAN) proteins in a subject (e.g., a subject having or suspected of having a disease associated with a CAG and/or CTG repeat expansion). In some embodiments, methods described by the disclosure comprise detecting one or more RAN proteins in a biological sample obtained from a subject by an immunoassay using one or more antibodies that target homopolymeric repeat regions of RAN proteins. In some embodiments, the disclosure relates to kits comprising one or more antibodies that target homopolymeric repeat regions of RAN proteins, and an immunoassay plate and/or reagents. In some embodiments, the disclosure provides methods of producing anti-RAN protein antibodies. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/767549 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6875 (20130101) Original (OR) Class G01N 2800/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069134 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan B. Martin (Nashville, Tennessee); William A. Grissom (Nashville, Tennessee); Mark A. Griswold (Cleveland, Ohio) |
| ABSTRACT | A system and method is provided using a nuclear magnetic resonance (NMR) system. The method includes applying an off-resonance radio frequency (RF) pulse using a radio-frequency coil that is spatially inhomogeneous to induce a B1-dependent resonant frequency shift in spins in a subject and, in the presence of the off-resonance RF pulse, applying a frequency-modulated, frequency-selective RF excitation pulse to spatially encode the spins in the subject. The method also includes acquiring NMR data from the subject that is spatially encoded and reconstructing the NMR data to produce a report of internal materials forming the subject. |
| FILED | Thursday, February 24, 2022 |
| APPL NO | 18/547549 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/543 (20130101) G01R 33/4831 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069321 | Cui |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Meng Cui (West Lafayette, Indiana) |
| ABSTRACT | An apparatus for large-scale dynamic imaging of a sample is described. The apparatus includes an optical detector, a light guide, a dichroic beam splitter, and a light source. The light guide includes a first portion and a second portion. The second defines a tapered shape such that a first diameter defined by a distal end of the second portion is smaller than a second diameter defined by a proximal end of the second portion. The dichroic beam splitter is positioned between the first portion and the second portion of the light guide. The light source is configured to direct a light beam through an external surface of the dichroic beam splitter. The dichroic beam splitter is configured to direct the light beam toward the second open end of the light guide and transfer the return emitted signal through the light guide to the optical detector. |
| FILED | Wednesday, August 30, 2023 |
| APPL NO | 18/239829 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 2201/08 (20130101) Optical Elements, Systems, or Apparatus G02B 21/361 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070838 | Smoqi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ziyad Smoqi (Lincoln, Nebraska); Prahalada Rao (Lincoln, Nebraska); Benjamin Bevans (Lincoln, Nebraska); Aniruddha Gaikwad (Lincoln, Nebraska) |
| ABSTRACT | Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for detection of defects in additive manufacturing. In some implementations, a method includes obtaining an image representing a volume of molten material; extracting one or more features from the image; providing the one or more features to a trained machine learning model; obtaining output from the trained machine learning model; and determining, using the output, a defect in a part. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/240879 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 12/90 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) Image Data Processing or Generation, in General G06T 7/0004 (20130101) Original (OR) Class G06T 2207/20081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240071201 | Teachman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bethany A. Teachman (Charlottesville, Virginia); Laura E. Barnes (Earlysville, Virginia); Mehdi Boukhechba (Charlottesville, Virginia) |
| ABSTRACT | An anxiety microdose intervention delivery system receives, from a plurality of biomarker sensors, a positional parameter associated with a user's position, a social parameter associated with a user's social interaction, and a set of physiological parameters associated with a user's physiological state. The system can determine, using a recommendation algorithm, that a user is in a possible state of anxiety. The system can generate, based at least in part on the determination that the user is in the possible state of anxiety, data for displaying microdose intervention content on the user device. The microdose intervention content can be configured to better manage the anxiety. The system can receive user interaction with the microdose intervention content and transmit a report of the user interaction with the intervention content. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/241133 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) A61B 5/02055 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240071562 | YAMAMOTO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CarbGeM Inc. (Tokyo, Japan); NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (Tokyo, Japan) |
| ASSIGNEE(S) | CarbGeM Inc. (Tokyo, Japan); NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (Tokyo, Japan) |
| INVENTOR(S) | Kei YAMAMOTO (Tokyo, Japan); Isao MIYATSUKA (Tokyo, Japan); My An LE (Tokyo, Japan) |
| ABSTRACT | An example system according to the present invention can provide a more convenient system. A mobile terminal device includes an acquisition unit configured to acquire information specifying a bacterial strain and information specifying a sensitivity rate, and a specification unit configured to specify, using an antibiogram, information on one or a plurality of antimicrobial agents, each of the antimicrobial agents satisfying the sensitivity rate for the bacterial strain. The information on the antimicrobial agent includes a sensitivity rate of the antimicrobial agent, a spectrum score for the antimicrobial agent, and/or an AWaRe classification of the antimicrobial agent. The mobile terminal device includes a display unit configured to display a plurality of sensitivity rate candidates, and the sensitivity rate is selected, by a user, from among the plurality of sensitivity rate candidates. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 18/284414 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/945 (20220101) G06V 20/693 (20220101) G06V 20/698 (20220101) G06V 2201/03 (20220101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240071566 | HELLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan- Kettering Cancer Center (New York, New York); Sloan-Kettering Institute For Cancer Research (New York, New York); Memorial Hospital for Cancer and Allied Diseases (New York, New York); Lehigh Univer (Bethlehem, Pennsylvania); University of Maryland (College Park, Maryland); National Institue of Standards and Technolgy (Gaitherburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel A. HELLER (New York, New York); Mijin KIM (New York, New York); Yoona YANG (Bethlehem, Pennsylvania); Yuhuang WANG (Laurel, Maryland); Anand JAGOTA (Bethlehem, Pennsylvania); Ming ZHENG (Rockville, Maryland) |
| ABSTRACT | Disclosed are approaches to acquiring a “disease fingerprint” from biosamples by collecting large data sets of physicochemical interactions to a sensor array composed of organic color center-modified carbon nanotubes. Array responses from subjects may be used to train and validate machine learning models to differentiate diseases and healthy individuals. The trained learning models may be used to subsequently classify patients based on nanosensor array emission data. |
| FILED | Thursday, January 20, 2022 |
| APPL NO | 18/262300 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/10 (20190101) G06N 20/20 (20190101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/20 (20190201) Original (OR) Class G16B 25/00 (20190201) G16B 40/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240065572 | Galeotti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania); University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Michael Galeotti (Pittsburgh, Pennsylvania); George DeWitt Stetten (Pittsburgh, Pennsylvania); Chun-Yin Huang (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided is a system, method, and computer program product for tracking an object based on skin images. A method includes capturing, with at least one computing device, a sequence of images with a stationary or movable camera unit arranged in a room, the sequence of images including the subject and an object moving relative to the subject, and determining, with at least one computing device, the pose of the object with respect to the subject in at least one image of the sequence of images based on computing or using a prior surface model of the subject, a surface model of the object, and an optical model of the stationary or movable camera unit. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/280283 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/061 (20130101) Original (OR) Class A61B 5/0077 (20130101) A61B 5/742 (20130101) Image Data Processing or Generation, in General G06T 7/75 (20170101) G06T 7/246 (20170101) G06T 2207/10132 (20130101) G06T 2207/20016 (20130101) G06T 2207/30088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240065981 | Wolcott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | San Jose State University (San Jose, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abraham Wolcott (Scotts Valley, California); Krishna Govindaraju (Santa Clara, California); Sandra Ladjadj (San Jose, California); Daniel Labunsky (San Jose, California); Ezhioghode Uwadiale (San Jose, California) |
| ABSTRACT | Various aspects described herein relate to a functionalized nanoscale substrate. The functionalized nanoscale substrate includes a functionalized surface of the substrate that includes a boronated portion. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/454139 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 9/1277 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066037 | BAVARI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (Stevenage, United Kingdom); THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (Frederick, Maryland); THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sina BAVARI (Collegeville, Pennsylvania); Christopher D. KANE (Collegeville, Pennsylvania); Andrew James PEAT (Collegeville, Pennsylvania); Veronica SOLOVEVA (Collegeville, Pennsylvania) |
| ABSTRACT | Provided are cathepsin inhibitor compounds and pharmaceutically acceptable salts thereof, and combinations thereof, for use in the treatment or prophylaxis of viral disease in an animal. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/913870 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066302 | Halpern |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ian Loren Halpern (Mill Valley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ian Loren Halpern (Mill Valley, California) |
| ABSTRACT | A method of treating a neurological condition in a medical patient includes implanting first and second sets of leads at first and second target tissue sites, receiving first and second signals from the first and second sets of leads, determining that a parameter of the first signal satisfies a condition, determining that a parameter of the second signal does not satisfy the condition, and removing only the second set of leads from the medical patient. Each lead comprises one electrode or more than one electrodes spaced apart from each other along a length of each lead. The first signal is indicative of electrical activity at the first target tissue site during an event, and the second signal is indicative of electrical activity at the second target tissue site during the event. |
| FILED | Tuesday, March 07, 2023 |
| APPL NO | 18/118666 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/025 (20130101) A61N 1/3787 (20130101) A61N 1/36135 (20130101) Original (OR) Class A61N 1/37229 (20130101) A61N 1/37235 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066443 | Brancazio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David Brancazio (Cambridge, Massachusetts); Allan S. Myerson (Cambridge, Massachusetts); Mohammad A. Azad (Greensboro, North Carolina); Gregory J. Hammersmith (Windsor, Connecticut); Gerard Capellades Mendez (Cambridge, Massachusetts); Clemence Neurohr (Cambridge, Massachusetts); Kersten Rapp (Medway, Massachusetts); Naomi Elizabeth Barbara Briggs (Rockville, Maryland) |
| ABSTRACT | Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described. |
| FILED | Friday, September 01, 2023 |
| APPL NO | 18/460353 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) Separation B01D 29/05 (20130101) B01D 29/075 (20210801) B01D 29/86 (20130101) Original (OR) Class B01D 29/608 (20130101) B01D 35/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066834 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Darryl A. Boyd (Alexandria, Virginia); Jason D. Myers (Alexandria, Virginia); Vinh Q. Nguyen (Fairfax, Virginia); Daniel J. Gibson (Cheverly, Maryland); Colin C. Baker (Alexandria, Virginia); Woohong Kim (Lorton, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | A bonded optical assembly comprising infrared-transparent materials. The assembly comprises two or more infrared transparent optical elements and a polymer comprising at least one chalcogenide element and crosslinking moieties between the infrared-transparent optical elements. The crosslinking moieties may be organic, inorganic, or both. |
| FILED | Tuesday, November 07, 2023 |
| APPL NO | 18/387576 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/12 (20130101) Original (OR) Class B32B 7/023 (20190101) B32B 33/00 (20130101) B32B 37/1207 (20130101) B32B 2305/72 (20130101) B32B 2307/412 (20130101) B32B 2307/704 (20130101) B32B 2318/00 (20130101) B32B 2551/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 11/04 (20130101) C09J 163/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067332 | Palcic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter X. Palcic (Bethany, Connecticut); Cole Steven Twing (Castle Pines, Colorado); Yuriy Gmirya (Woodbridge, Connecticut) |
| ABSTRACT | A rotary shaft assembly includes a rotary shaft having a first end portion, a second end portion opposite the first end portion, a longitudinal axis extending centrally through the first and second end portions, and a shaft body that defines a bore between the first and second end portions. An anti-flailing mechanism is positioned within the bore of the shaft body. The anti-flailing mechanism is coupled to rotary shaft and extends at least partially between the first and second end portions to contain the rotary shaft about the longitudinal axis when the rotary shaft fails. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895703 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/10 (20130101) Original (OR) Class B64C 27/14 (20130101) B64C 27/26 (20130101) B64C 2027/8236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067575 | Trice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rodney Wayne Trice (Xenia, Ohio); Edwin Sebastian Romero (West Lafayette, Indiana); Eduardo Barocio Vaca (West Lafayette, Indiana); Robert Byron Pipes (Lafayette, Indiana) |
| ABSTRACT | Methods of manufacturing carbon/carbon preforms and carbon/carbon composites formed therefrom. Such a method includes extruding a polymer composite material using an extrusion deposition additive manufacturing process to form a preform, and heating the preform via pyrolysis to form the carbon/carbon composite. |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/457912 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 70/10 (20200101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) C04B 35/83 (20130101) Original (OR) Class C04B 35/62873 (20130101) C04B 2235/48 (20130101) C04B 2235/422 (20130101) C04B 2235/661 (20130101) C04B 2235/5248 (20130101) C04B 2235/6021 (20130101) C04B 2235/6026 (20130101) C04B 2235/6562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067603 | POTTER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (MINNEAPOLIS, Minnesota); ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David A. POTTER (MINNEAPOLIS, Minnesota); Zhijun GUO (MINNEAPOLIS, Minnesota); Gunda GEORG (MINNEAPOLIS, Minnesota); Kwon Ho HONG (MINNEAPOLIS, Minnesota); Jianxun LEI (MINNEAPOLIS, Minnesota); Elizabeth AMBROSE (MINNEAPOLIS, Minnesota); Kris WHITE (New York, New York) |
| ABSTRACT | Biguanide compounds of formula where R1 comprises a cubanyl-substituted alkyl and R2 comprises a substituted or unsubstituted alkyl, and their use in the treatment of cancers and viral infections are described. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/258076 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Acyclic or Carbocyclic Compounds C07C 279/26 (20130101) Original (OR) Class C07C 2603/90 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067685 | de la Fuente-Nunez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | César de la Fuente-Nunez (Philadelphia, Pennsylvania); Angela Arciello (Portici, Italy); Angela Cesaro (Philadelphia, Pennsylvania); Marcelo Der Torossian Torres (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided herein are antimicrobial peptides, as well as methods of treating a microbial infection, methods of treating inflammation, and methods of reducing biofilm formation, using the disclosed antimicrobial peptides. |
| FILED | Thursday, June 08, 2023 |
| APPL NO | 18/331331 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 14/4747 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067780 | Ridenour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | James A. Ridenour (Arlington, Virginia); Olga Baturina (Burke, Virginia); Albert Epshteyn (Potomac, Maryland); Bethany Hudak (Accokeek, Maryland); Hannah Marie Ashberry (Alexandria, Virginia) |
| ABSTRACT | Described herein is the preparation of solid acid fuel cell (SAFC) electrode materials suitable for intermediate temperature (200° C.-300° C.) oxygen reduction reaction (ORR) catalysis via anaerobic, in vacuo pyrolysis of metal-organic coordination polymer precursor materials with divalent metals (e.g. Pt or Pd) as nodes to form small, catalytically active nanoparticles inside a porous, electrically conductive carbonized framework. |
| FILED | Wednesday, August 30, 2023 |
| APPL NO | 18/240088 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068042 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Edison T. Liu (Bar Harbor, Maine); Francesca Menghi (Bar Harbor, Maine) |
| ABSTRACT | Provided herein, in some embodiments, are novel methods for predicting response to a platinum-based chemotherapeutic agent in triple negative breast cancer and ovarian carcinoma. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 18/272260 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068106 | Ashberry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Hannah Marie Ashberry (Alexandria, Virginia); Albert Epshteyn (Potomac, Maryland); James A. Ridenour (Arlington, Virginia); William A. Maza (Silver Spring, Maryland); Olga Baturina (Burke, Virginia) |
| ABSTRACT | Deposition of Pt nanoparticles on UiO metal organic frameworks via solvothermal reduction is achieved by reducing Pt acetylacetonate (Pt(acac)2) in a UiO-66 and N,N-dimethylformamide (DMF) mixture at, for example, 130° C. for 18 hrs. Modification of reaction temperature and time can control the size of the Pt nanoparticles. |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/238794 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 22/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068427 | Noftz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Edward Noftz (Villa Park, Illinois); Joseph Stephen Jewell (West Lafayette, Indiana); Andrew James Shuck (Indianapolis, Indiana); Jonathan Poggie (West Lafayette, Indiana); Andrew Nixon Bustard (South Bend, Indiana); Thomas James Juliano (Granger, Indiana) |
| ABSTRACT | Systems and methods capable for use in the development of high-speed, shape-transitioning, inward-turning inlets for air-breathing hypersonic vehicles, and inlets formed thereby. The systems and methods preferably provide for designing high-speed inlets for air-breathing hypersonic vehicles, wherein unique solutions are defined in each osculating plane of the inlet. Such systems and methods optionally provide an optimization process for tuning the post throat-shock Mach number of the inlet, and/or designs a shock-capture surface using a parallel-streamlines methodology, and/or a double cowl-lip geometry to allow flow to spill overboard. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/240818 |
| CURRENT CPC | Jet-propulsion Plants F02K 7/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068453 | CHARI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Celia S. CHARI (Pasadena, California); Katherine T. FABER (Pasadena, California); Bryan W. McENERNEY (Pasadena, California); Richard R. HOFER (Pasadena, California); James A. WOLLMERSHAUSER (Alexandria, Virginia); Edward P. GORZKOWSKI, III (Severna Park, Maryland) |
| ABSTRACT | Aspects disclosed herein include graphite and hexagonal boron nitride bimaterials, methods of making these bimaterials, and electric propulsion devices or thrusters with these bimaterials. Aspects disclosed herein include electric propulsion devices comprising: at least one portion comprising or formed of a monolithic bimaterial; wherein the monolithic bimaterial comprises a graphite material and a hexagonal boron nitride material; and wherein the graphite material and hexagonal boron nitride material are monolithically integrated in the bimaterial. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/238101 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/413 (20230801) Non-metallic Elements; Compounds Thereof; C01B 32/21 (20170801) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068808 | Lunt |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Gary A. Lunt (Riverside, California) |
| ABSTRACT | A method of determining geo-reference data for a portion of a measurement area includes providing a monitoring assembly comprising a ground station, providing an imaging assembly comprising an imaging device with a lens operably coupled to an aerial device, hovering the aerial device over a measurement area, capturing at least one image of the measurement area within the imaging device, transmitting the at least one image to the ground station using a data transmitting assembly, and scaling the at least one image to determine the geo-reference data for the portion of the measurement area by calculating a size of a field-of-view (FOV) of the lens based on a distance between the imaging device and the measurement area. |
| FILED | Friday, July 07, 2023 |
| APPL NO | 18/219255 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 3/08 (20130101) Original (OR) Class Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/38 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/49 (20130101) G01S 19/485 (20200501) Image Data Processing or Generation, in General G06T 7/73 (20170101) G06T 7/246 (20170101) Image or Video Recognition or Understanding G06V 20/52 (20220101) Traffic Control Systems G08G 5/0013 (20130101) G08G 5/0026 (20130101) G08G 5/0069 (20130101) G08G 5/0078 (20130101) G08G 5/0086 (20130101) Pictorial Communication, e.g Television H04N 23/69 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068890 | Aga et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roberto Aga (Beavercreek, Ohio); Emily Heckman (Oakwood, Ohio) |
| ABSTRACT | A multi-junction resistance strain gauge comprises a substrate; a sinterable ink deposited directly on the substrate forming a non-conductive pattern; a stripe pattern generated on the sinterable ink by sintering, the stripe pattern having one or more non-conductive gaps, the stripe pattern having a first electrical conductivity; a sintered bridge across each of the one or more gaps and providing electrical continuity through the stripe and across the gaps, each bridge having a second electrical conductivity which is lower than the first electrical conductivity. The substrate is a non-conductive material or a conductive material coated with a thin insulator on which the stripe pattern is generated. The sinterable ink is a silver ink. The first electrical conductivity and the second electrical conductivity comprise different electrical conductivity. The first electrical conductivity of the stripe is a factor of about 1.7 or more higher than the second electrical conductivity of the bridge. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/822866 |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/2287 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069125 | Shirazi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Paymon Shirazi (Corona, California); Subrata Sanyal (Eastvale, California) |
| ABSTRACT | Disclosed are apparatus and methods for sensing and measurement of magnetic fields that are insensitive to temperature, and respond linearly to the magnitude of the magnetic field. In particular, the apparatus and methods include the use of a resistance network including at least one fluorinated graphene foam (FGF) magnetoresistive device. Measurement of a voltage drop across at least one FGF magnetoresistive device is correlated to either merely the presence of a magnetic field or for measurement of at least a scalar magnitude value of the magnetic field. The use of FGF affords both temperature-insensitivity and linear magnetic field responsivity. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895407 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/09 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069368 | Panuski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Louis Panuski (Somerville, Massachusetts); Ian Robert Christen (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ABSTRACT | Methods and systems are described for precisely adjusting characteristics of microfabricated devices after device fabrication. The adjustments can be carried out in parallel on a plurality of the microfabricated devices. By carrying out the adjustment process, uniformity of feature sizes to a few picometers (one standard deviation) and corresponding uniformity of operating characteristics for a plurality of microfabricated devices are possible. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/898147 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/362 (20130101) B23K 2101/40 (20180801) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069516 | Welch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory Welch (Orlando, Florida); Gerd Bruder (Orlando, Florida); Ryan Schubert (Orlando, Florida); Austin Erickson (Orlando, Florida) |
| ABSTRACT | The invention pertains to methods for monitoring the operational status of a home automation system through extrinsic visual and audible means. Initial training periods involve capturing image and audio data representative of nominal operation, which is then processed to identify operational indicators. Unsupervised machine learning models are trained with these indicators to construct a model of normalcy and identify expectation violations in the system's operational pattern. After meeting specific stopping criteria, real-time monitoring is initiated. When an expectation violation is detected, contrastive collages or sequences are generated comprising nominal and anomalous data. These are then transmitted to an end user, effectively conveying the context of the detected anomalies. Further features include providing deep links to smartphone applications for home automation configuration and the use of auditory scene analysis techniques. The invention provides a multi-modal approach to home automation monitoring, leveraging machine learning for robust anomaly detection. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/240731 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/0428 (20130101) Original (OR) Class G05B 2219/2642 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069921 | Cline et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott Cline (Portland, Oregon); Robert Pawlowski (Beaverton, Oregon); Joshua Fryman (Corvallis, Oregon); Ivan Ganev (Portland, Oregon); Vincent Cave (Hillsboro, Oregon); Sebastian Szkoda (Gdansk, Poland); Fabio Checconi (Fremont, California) |
| ABSTRACT | Technology described herein provides a dynamically reconfigurable processing core. The technology includes a plurality of pipelines comprising a core, where the core is reconfigurable into one of a plurality of core modes, a core network to provide inter-pipeline connections for the pipelines, and logic to receive a morph instruction including a target core mode from an application running on the core, determine a present core state for the core, and morph, based on the present core state, the core to the target core mode. In embodiments, to morph the core, the logic is to select, based on the target core mode, which inter-pipeline connections are active, where each pipeline includes at least one multiplexor via which the inter-pipeline connections are selected to be active. In embodiments, to morph the core, the logic is further to select, based on the target core mode, which memory access paths are active. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/477884 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3885 (20130101) Original (OR) Class G06F 9/30036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069958 | Hornung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bryan Hornung (Plano, Texas); David Patrick (McKinney, Texas) |
| ABSTRACT | Devices and techniques for handling breakpoints in a multi-element processor are described herein. A compute node includes a hybrid threading processor and hybrid threading fabric, where the hybrid threading fabric comprises a plurality of memory-compute tiles, where each of the memory-compute tiles include respective processing and storage elements used to execute a kernel, and where each of the memory-compute tiles includes a breakpoint controller to initiate a breakpoint for the plurality of memory-compute tiles. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/899710 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/485 (20130101) Original (OR) Class G06F 9/30076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069962 | SHREVE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Matthew A. SHREVE (Campbell, California); Eric D. COCKER (Redwood City, California) |
| ABSTRACT | A method and system for implementing a task scheduler are provided in a resource constrained computation system that uses meta data provided for each task (e.g. data analysis algorithm or sensor sampling protocol) to determine which tasks should be run in a particular wake cycle, the order in which the tasks are run, and how the tasks are distributed across the available compute resources. When a task successfully completes, it's time of execution is logged in order to provide a reference for when that task should be run again. Task meta data is formatted in a manner to allow for simple integration of new tasks into the processing architecture. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898797 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3838 (20130101) G06F 9/4881 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069990 | Blais et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stéphane Yannick Blais (Framingham, Massachusetts); Michael Hassan Atighetchi (Framingham, Massachusetts); Samuel Cunningham Nelson (Sudbury, Massachusetts); Christopher Lawerence Willig (Chelmsford, Massachusetts) |
| ABSTRACT | Techniques are described herein for a messaging system to allow publishers that are aware of the identities of their respective subscribers to target content at those subscribers directly. This may be accomplished by allowing users and other targets (e.g., groups) to register their identities at particular computing nodes of a system. Then publishers (e.g., applications) may send out messages targeted at particular identities, and a publishing system may forward messages to appropriate nodes based on which identities are registered at those nodes. Legacy applications that are not able to target particular identities may instead connect to application adapters that are configured to learn which identities should be targeted by each application. In addition, anonymized identities may be used for application messages that need to cross between domains having differing security levels. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 17/822628 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/546 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070112 | Hornung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bryan Hornung (Plano, Texas); Douglas Vanesko (Dallas, Texas); David Patrick (McKinney, Texas) |
| ABSTRACT | Devices and techniques for loading contexts in a coarse-grained reconfigurable array processor are described herein. A system or apparatus may include context load circuitry operable to load context for a coarse-grained reconfigurable array processor, where the context load circuitry is configured to: (a) receive a kernel identifier; (b) access a first registry to obtain a context mask base address; (c) determine a context mask address from the context mask base address and the kernel identifier; (d) access a second registry to obtain a context state base address; (e) determine a context state address from the context state base address and the kernel identifier; (f) use a context mask at the context mask address to determine corresponding active context state; and (g) load the corresponding active context state into the coarse-grained reconfigurable array processor. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/899714 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30018 (20130101) G06F 15/80 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070422 | Church |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to methods of synthesizing de novo a polynucleotide storing data using a programmable template independent polymerase. |
| FILED | Tuesday, October 18, 2022 |
| APPL NO | 18/047328 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/00 (20130101) G06K 19/022 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/123 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) G16B 30/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070467 | Nataraj et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayachitra, Inc. (Santa Barbara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lakshmanan Nataraj (Chennai, India); Tajuddin Manhar Mohammed (Goleta, California); Tejaswi Nanjundaswamy (San Jose, California); Michael Gene Goebel (Santa Barbara, California); Bangalore S. Manjunath (Santa Barbara, California); Shivkumar Chandrasekaran (Santa Barbara, California) |
| ABSTRACT | Systems, devices, methods and instructions are described for detecting GAN generated images. On embodiment involves receiving an images, generating co-occurrence matrices on color channels of the image, generating analysis of the image by using a convolutional neural network trained to analyze image features of the images based on the generated co-occurrence matrices and determining whether the image is a GAN generated image based on the analysis. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/384144 |
| CURRENT CPC | Electric Digital Data Processing G06F 18/217 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) G06N 3/088 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/454 (20220101) G06V 10/764 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240071055 | Welch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory Welch (Orlando, Florida); Gerd Bruder (Orlando, Florida); Ryan Schubert (Orlando, Florida); Austin Erickson (Orlando, Florida) |
| ABSTRACT | The invention pertains to methods for monitoring the operational status of a home automation system through extrinsic visual and audible means. Initial training periods involve capturing image and audio data representative of nominal operation, which is then processed to identify operational indicators. Unsupervised machine learning models are trained with these indicators to construct a model of normalcy and identify expectation violations in the system's operational pattern. After meeting specific stopping criteria, real-time monitoring is initiated. When an expectation violation is detected, contrastive collages or sequences are generated comprising nominal and anomalous data. These are then transmitted to an end user, effectively conveying the context of the detected anomalies. Further features include providing deep links to smartphone applications for home automation configuration and the use of auditory scene analysis techniques. The invention provides a multi-modal approach to home automation monitoring, leveraging machine learning for robust anomaly detection. |
| FILED | Wednesday, September 06, 2023 |
| APPL NO | 18/461746 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/0428 (20130101) Original (OR) Class G05B 2219/2642 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240071445 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian-Ping Wang (Minneapolis, Minnesota); Brandon Zink (Minneapolis, Minnesota); Yang Lv (Minneapolis, Minnesota) |
| ABSTRACT | A circuit includes a first two-state device, a second two-state device and a third two-state device, each two-state device having a first resistance in a first state and a second resistance in a second state. First control elements are configured to apply a first voltage to the first two-state device to stochastically place the first two-state device in either the first state or the second state. Second control elements are configured to apply a second voltage to the second two-state device to stochastically place the second two-state device in either the first state or the second state. Third control elements are configured to send respective currents through the first two-state device and the second two-state device so as to place the third two-state device in either the first state or the second state based on the state of the first two-state device and the state of the second two-state devices. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/454441 |
| CURRENT CPC | Static Stores G11C 7/109 (20130101) G11C 7/222 (20130101) Original (OR) Class G11C 7/1069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240071738 | Rubenstein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mitchell H Rubenstein (Beavercreek, Ohio); Christin M Duran (Dayton, Ohio); John T Kelly (Xenia, Ohio); Jae Hwan Lee (Watervliet, New York); Sarah Pfahler (Miamisburg, Ohio); Robert M Bradford (Dayton, Ohio) |
| ABSTRACT | The present invention relates to a method of improving a mass spectrometer, a module for improving a mass spectrometer and an improved mass spectrometer. The aforementioned method uses machine learning and can greatly reduce the number and timeframe for the elimination of false positives to a couple of hours. Such method can be integrated into a mass spectrometer by inserting a computer module programmed with such method into a mass spectrometer's computer system. |
| FILED | Friday, July 21, 2023 |
| APPL NO | 18/224612 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072180 | Chaurasia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GlobalFoundries U.S. Inc. (Malta, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Saloni Chaurasia (Leander, Texas); Jeffrey Johnson (Essex Junction, Vermont); Vibhor Jain (Essex Junction, Vermont); Crystal R. Kenney (Waterford, New York); Sudesh Saroop (Poughkeepsie, New York); Teng-Yin Lin (Clifton Park, New York); John J. Pekarik (Underhill, Vermont) |
| ABSTRACT | Structures for a varactor diode and methods of forming same. The structure comprises a first semiconductor layer including a section on a substrate, a second semiconductor layer on the section of the first semiconductor layer, a third semiconductor layer on the second semiconductor layer, and a doped region in the section of the first semiconductor layer. The section of the first semiconductor layer and the doped region have a first conductivity type, and the second semiconductor layer comprises silicon-germanium having a second conductivity type opposite to the first conductivity type, and the third semiconductor layer has the second conductivity type. The doped region contains a higher concentration of a dopant of the first conductivity type than the section of the first semiconductor layer. The second semiconductor layer abuts the first section of the first semiconductor layer along an interface, and the doped region is positioned adjacent to the interface. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 17/896711 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/93 (20130101) Original (OR) Class H01L 29/1095 (20130101) H01L 29/66174 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072397 | Fortier |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aleksandra Fortier (Coppell, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aleksandra Fortier (Coppell, Texas) |
| ABSTRACT | The disclosed principles provide techniques for 3D fabrication of sensing systems embedded inside battery cells and provide cell parameter data for a comprehensive and robust battery management system. The disclosed principles provide online and real-time monitoring battery state-of-health down to the individual cell level of each battery using embedded sensors on one or more of the internal layers of a cell, such as the dielectric separators found in such battery cells. The implementation of the disclosed principles in individual battery cells therefore provides an increased likelihood to mitigate catastrophic failures in batteries. In addition, the disclosed fabrication processes for printing sensors directly on one or more of the components or layers within each individual battery cell significantly reduce manufacturing steps required by conventional battery management systems. The disclosed principles also provided for a unique silica-based ink for use in the 3D printing of such embedded cell sensing components. |
| FILED | Thursday, November 02, 2023 |
| APPL NO | 18/500948 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/48 (20130101) H01M 10/486 (20130101) H01M 50/569 (20210101) Original (OR) Class H01M 2010/4278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072422 | Muhleman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Howard Muhleman (El Cajon, California); Alexandru Hening (San Diego, California) |
| ABSTRACT | An antenna extender and an antenna extended with a laser induced includes a laser source and an antenna feed. The laser source is capable of emitting a laser beam along an axis with sufficient power to produce a laser induced plasma in an atmosphere along the axis of the laser beam. The antenna feed extends along the axis for coupling between a radiofrequency signal and the laser induced plasma. The antenna feed extended with the laser induced plasma has an enhanced radiation efficiency for the radiofrequency signal that is greater than the antenna feed that is not extended and has a stub radiation efficiency for the radiofrequency signal when the laser source is deactivated and does not emit the laser beam. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/894737 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072730 | Portillo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Salvador Portillo (Albuquerque, New Mexico); Ahmed Elshafiey (Albuquerque, New Mexico) |
| ABSTRACT | A magnetically insulated line oscillator (MILO) that is a high power microwave (HPM) source. A cross field device with a plurality of azimuthally extending spaced apart slats. |
| FILED | Thursday, December 22, 2022 |
| APPL NO | 18/087120 |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 9/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072889 | Doddridge |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Lance S. Doddridge (Ontario, California) |
| ABSTRACT | Methods, apparatus, and systems are disclosed for implementing a fiber optic reflectance standard (FORS) for testing and/or calibration of a test instrument (TI), which provides a traceable means to calibrate the making optical return loss measurements (ORLM). The apparatus for implementing the FORS may include an optical splitter, first and second optical inputs coupled to the optical splitter, and an optical fiber having first and second ends, and coupled to the optical splitter at the first end of the optical fiber. Furthermore, the apparatus includes an attenuator (e.g., a mechanical attenuator) configured to contain a portion of the optical fiber between the first and second ends and selectively attenuate optical signal gain of the optical fiber. The testing and/or calibration results in an uncertainty that is at least four times better than a typical test instrument. |
| FILED | Monday, August 21, 2023 |
| APPL NO | 18/236223 |
| CURRENT CPC | Transmission H04B 10/071 (20130101) Original (OR) Class H04B 10/2537 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072991 | TORRES et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Francisco E. TORRES (San Jose, California); Eric D. COCKER (Redwood City, California) |
| ABSTRACT | A system and method are provided wherein encrypted data is stored in modular lockers on a first storage volume associated with a high-power microprocessor deployed in a system. Each encrypted locker maps, for example, to a specific time segment (e.g., one day) which simplifies mounting of the encrypted volume for data access and reduces the locker size for external access of data while encrypted (e.g., via Wifi). New data in a second storage volume associated with and generated by a low-power microprocessor associated with the system gets transferred to the encrypted data store during wake cycles of the high-power microprocessor. To manage space on the first storage volume, time stamps associated with each encrypted locker allows simple removal of files older than a specified time period by removing of any encrypted lockers older than that threshold. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898826 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/16 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) Original (OR) Class H04L 2209/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240073078 | JOHNSON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peraton Labs Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William JOHNSON (Basking Ridge, New Jersey); Kiran REGE (Basking Ridge, New Jersey); Achilles KOGIANTIS (Basking Ridge, New Jersey) |
| ABSTRACT | There is set forth herein, in one embodiment, receiving, by a transceiver of a UE device an aggregate signal stream, the aggregate signal stream including an aggregate of base station downlink signal streams from a plurality of base stations; and processing the aggregate signal stream. |
| FILED | Monday, November 06, 2023 |
| APPL NO | 18/502860 |
| CURRENT CPC | Transmission H04B 7/088 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/2657 (20130101) Original (OR) Class Wireless Communication Networks H04W 48/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240073152 | COCKER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Eric D. COCKER (Redwood City, California); Matthew A. SHREVE (Campbell, California); Francisco E. TORRES (San Jose, California) |
| ABSTRACT | A system and method provide a combination of a modular message structure, a priority-based message packing scheme, and a data packet queue management system to optimize the information content of a transmitted message in, for example, the Ocean of Things (OoT) environment. The modular message structure starts with a header that provides critical information and reference points for time and location. The rest of the message is composed of modular data packets, each of which has a data ID section that the message decoder uses for reference when reconstructing the message contents, an optional size section that specifies the length of the following data section if it can contain data of variable length, and a data section that can be compressed in a manner unique to that data type. The message packing scheme uses a combination of priority level and minimum reporting interval, both of which are dynamically configurable for each data packet type, to maximize the value of the information contained in the modular data packets included in each message. Finally, the data packet queues manage temporary storage of data packets that have been generated but not yet included in an outgoing message. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898985 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/06 (20130101) H04L 47/564 (20130101) H04L 47/6275 (20130101) Original (OR) Class H04L 69/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240073238 | LANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ObjectSecurity LLC (San Diego, California) |
| ASSIGNEE(S) | ObjectSecurity LLC (San Diego, California) |
| INVENTOR(S) | Ulrich LANG (San Diego, California); Reza FATAHI (Los Angeles, California); Jason KRAMER (Los Angeles, California) |
| ABSTRACT | Method and system for analyzing computing devices for properties of at least one computer software in the at least one computing system, includes loading, input data for at least one computer software; determining a result pertaining to vulnerabilities present or expected to be present within the computer software; mapping vulnerabilities to frameworks, determining a result pertaining to the outcome of the vulnerability-to-framework mapping; generating, an output data describing the at least one result; storing the output data pertaining to the result in a memory; and determining, if the result satisfies a predetermined condition, and if so, executing an action corresponding to the result on the computing system. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/237120 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/1433 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240074218 | Forrest et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Xin Xiao (Ann Arbor, Michigan); Jeramy D. Zimmerman (Golden, Colorado); Kevin Bergemann (Ann Arbor, Michigan); Anurag Panda (Ann Arbor, Michigan); Brian E. Lassiter (San Francisco, California); Mark E. Thompson (Anaheim, California); Andrew N. Bartynski (Los Angeles, California); Cong Trinh (San Jose, California) |
| ABSTRACT | Disclosed herein are organic photosensitive devices including at least one exciton-blocking charge carrier filter. The filters comprise a mixture of at least one wide energy gap material and at least one electron or hole conducting material. As described herein, the novel filters simultaneously block excitons and conduct the desired charge carrier (electrons or holes). |
| FILED | Wednesday, March 15, 2023 |
| APPL NO | 18/184497 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Organic electric solid-state devices H10K 30/353 (20230201) Original (OR) Class H10K 85/211 (20230201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240066510 | Matzger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam J. Matzger (Ann Arbor, Michigan); Keenan Wright (Ann Arbor, Michigan) |
| ABSTRACT | A method of activating a metal-organic framework material can include solvent exchanging the metal organic framework material with DME and then applying a vacuum to remove the DME and any residual solvent. |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/239396 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/1691 (20130101) Original (OR) Class B01J 31/1815 (20130101) B01J 2231/20 (20130101) B01J 2531/26 (20130101) B01J 2531/0216 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066748 | Bradshaw et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | InventWood LLC (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Allan Bradshaw (Seattle, Washington); Jack G. Winterowd (Puyallup, Washington) |
| ABSTRACT | This disclosure is directed to methods of separating wood veneer material by property measurements, and thereafter improving the properties of veneer material with property values lower than a target threshold value, until those materials meet or exceed that threshold values. In some aspects of the disclosure, veneer materials are prepared, non-destructively measured, and separated into passing and failing material collections. The failing material collection may then be treated to improve the density and flexural modulus of the material therein. Also disclosed herein are products and materials incorporating the treated veneer materials according to the disclosed methods. |
| FILED | Thursday, September 14, 2023 |
| APPL NO | 18/368472 |
| CURRENT CPC | Working Veneer or Plywood B27D 3/00 (20130101) Processes, Apparatus or Selection of Substances for Impregnating, Staining, Dyeing, Bleaching of Wood or Similar Materials, or Treating of Wood or Similar Materials With Permeant Liquids, Not Otherwise Provided for; Chemical or Physical Treatment of Cork, Cane, Reed, Straw or Similar Materials B27K 3/18 (20130101) B27K 3/025 (20130101) Original (OR) Class B27K 3/42 (20130101) B27K 2200/30 (20130101) B27K 2240/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066793 | Kumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vipin Kumar (Oak Ridge, Tennessee); Ahmed A. Hassen (Oak Ridge, Tennessee); Vlastimil Kunc (Oak Ridge, Tennessee); Cole Nielsen (Oak Ridge, Tennessee); David Nuttall (Oak Ridge, Tennessee) |
| ABSTRACT | A method of manufacturing an article is provided. The method includes feeding a polymeric material into an extruder including a nozzle, and feeding a continuous fiber into the extruder, the continuous fiber and the polymeric material together forming a molding compound. A three-dimensional preform is formed by discharging the molding compound from the nozzle onto a deposition surface. A mold charge is formed by positioning the three-dimensional preform within a mold that includes a top mold component and a bottom mold component. The mold charge is compression molded within the mold to form a finished article. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/237176 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/02 (20130101) B29C 64/30 (20170801) B29C 64/165 (20170801) Original (OR) Class B29C 64/209 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2307/04 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067594 | Saito et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tomonori Saito (Knoxville, Tennessee); Md Arifuzzaman (Knoxville, Tennessee) |
| ABSTRACT | A method of deconstructing polymer waste into at least one useful breakdown product, wherein the polymer waste contains at least one condensation polymer, the method comprising contacting the polymer waste with a catalyst comprising an organic nitrogen-containing base and a carboxylic acid or ester thereof, in the presence of a protic molecule selected from alcohols, diols, polyols, and amines, at an elevated temperature effective for inducing alcoholysis or aminolysis of the condensation polymer, wherein the useful breakdown products comprise monomer species capable of being polymerized, and the organic nitrogen-containing base has the following structure: wherein: R1, R2, R3, R4, R5, and R6 are independently selected from hydrogen atom, electron pair, and alkyl groups containing one to three carbon atoms, and wherein any adjacent two of R1, R2, R3, R4, R5, and R6 may optionally interconnect to form a five, six, or seven-membered ring. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/096849 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0244 (20130101) B01J 31/0251 (20130101) B01J 2231/64 (20130101) Acyclic or Carbocyclic Compounds C07C 67/32 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/28 (20130101) C08J 2367/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067779 | Beto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF TEXAS SAN ANTONIO (Austin, Texas) |
| INVENTOR(S) | Christopher Beto (Edwards Afb, California); Kirk S. Schanze (San Antonio, Texas); Adam S. Veige (Gainesville, Florida); Yajing Yang (San Antonio, Texas) |
| ABSTRACT | Provided herein are various metallopolymers and methods of making the same. |
| FILED | Friday, September 01, 2023 |
| APPL NO | 18/241443 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067792 | BAI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xianglan BAI (Ames, Iowa); Lusi A (Valencia, California); Harish RADHAKRISHNAN (Ames, Iowa) |
| ABSTRACT | One aspect of the present application relates to a method of decomposing a polymeric reactant. This method comprises reacting the polymeric reactant in an oxygen containing ionized gas plasma to decompose the polymeric reactant and produce oxygen-functionalized products. The reacting is carried out at a temperature of 20 to 450° C. Another aspect of the present application relates to a method of removing carbon dioxide and/or carbon monoxide from a gas mixture. This method comprises providing a gas mixture comprising carbon dioxide and/or carbon monoxide. The gas mixture is contacted with a polymeric reactant in an ionized gas plasma to remove carbon dioxide and/or carbon monoxide from the gas mixture and produce oxygen-functionalized products. |
| FILED | Thursday, August 17, 2023 |
| APPL NO | 18/451482 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/06 (20130101) C08F 8/50 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067829 | Jordan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Jordan (Storrs, Connecticut); Chen Jiang (Willimantic, Connecticut); Rishi Kumar (Ashford, Connecticut); Balakrishnan Nair (Sandy, Utah) |
| ABSTRACT | A thermal barrier coating for an internal combustion engine includes an insulating thermal spray coating, where a chosen material of the insulating thermal spray coating has a thermal conductivity lower than 2 W/mK in fully dense form and the chosen material includes a coefficient of thermal expansion within 5 ppm/K of a coefficient of thermal expansion of a material of a component of the internal combustion engine upon which the coating is placed. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/900860 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Original (OR) Class C09D 5/26 (20130101) C09D 7/61 (20180101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 3/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068015 | Cai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hong Cai (Los Alamos, New Mexico); Jian Song (Gainesville, Virginia) |
| ABSTRACT | The invention provides a rapid, sensitive and specific nucleic acid detection system which utilizes isothermal nucleic acid amplification in combination with a lateral flow chromatographic device, or DNA dipstick, for DNA-hybridization detection. The system of the invention requires no complex instrumentation or electronic hardware, and provides a low cost nucleic acid detection system suitable for highly sensitive pathogen detection. Hybridization to single-stranded DNA amplification products using the system of the invention provides a sensitive and specific means by which assays can be multiplexed for the detection of multiple target sequences. |
| FILED | Thursday, July 06, 2023 |
| APPL NO | 18/347910 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) C12Q 1/6816 (20130101) Original (OR) Class C12Q 1/6853 (20130101) C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068072 | Bez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Henrique Neves Bez (Santa Catarina, Brazil); Anis Biswas (Ames, Iowa); Arjun K. Pathak (Williamsville, New York); Yaroslav Mudryk (Ames, Iowa); Nikolai A. Zarkevich (Ames, Iowa); Viktor Balema (Greendale, Wisconsin); Vitalij K. Pecharsky (Ames, Iowa) |
| ABSTRACT | A method is provided of making a magnetocaloric alloy composition comprising Ni, Co, Mn, and Ti, which preferably includes certain beneficial substitutional elements, by melting the composition and rapidly solidifying the melted composition at a cooling rate of at least 100 K/second (Kelvin/second) to improve a magnetocaloric property of the composition. The rapidly solidified composition can be heat treated to homogenize the composition and annealed to tune the magneto-structural transition for use in a regenerator. |
| FILED | Thursday, November 02, 2023 |
| APPL NO | 18/500222 |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 8/1211 (20130101) Alloys C22C 1/02 (20130101) C22C 1/023 (20130101) Original (OR) Class C22C 1/0433 (20130101) C22C 19/03 (20130101) C22C 19/005 (20130101) C22C 30/00 (20130101) C22C 30/02 (20130101) C22C 30/06 (20130101) C22C 2202/02 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/10 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068363 | Su et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jiann-Cherng Su (Albuquerque, New Mexico); Jason P. Krein (Albuquerque, New Mexico); John Joseph Borchardt (Albuquerque, New Mexico); Richard Ellis Robey (Sandia Park, New Mexico); Andrew Alexander Wright (Albuquerque, New Mexico); Joseph Samuel Pope (Rio Rancho, New Mexico); Taylor Anthony Myers (Albuquerque, New Mexico); Mark C. Grubelich (Albuquerque, New Mexico); Douglas A. Blankenship (Albuquerque, New Mexico) |
| ABSTRACT | A drilling assembly for downhole to surface communications is provided. The drilling assembly includes a series of pipe segments coupled in fluid communication between a slip ring assembly and an end pipe portion. The slip ring assembly is coupled in data and fluid communication with the pipe segments. A surface communications link is in data communication with the drilling assembly via the slip ring assembly. An end pipe portion is coupled with the drilling assembly that includes an electronics assembly with electronic components for transferring data to the slip ring assembly via the drilling assembly. A drill bit is operably coupled with the end pipe portion for drilling a borehole. Each pipe segment includes an outer conductor portion, a hollow inner conductor portion, and a dielectric portion for electrical isolation between the outer conductor portion and the inner conductor portion. |
| FILED | Monday, November 06, 2023 |
| APPL NO | 18/387160 |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 17/0285 (20200501) E21B 47/13 (20200501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068417 | Singh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Caterpillar Inc. (Peoria, Illinois) |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Jaswinder Singh (Dunlap, Illinois); David Todd Montgomery (Edelstein, Illinois) |
| ABSTRACT | Operating a gaseous fuel engine system includes outputting control commands to a first fuel admission valve and a second fuel admission valve to admit, respectively, a gaseous fuel blend containing a gaseous hydrogen fuel (H2), and additional H2, into a gaseous fuel engine. An amount of the additional H2 is determined by way of the respective control command based on a performance target for an engine parameter varying on the basis of a relative amount of H2 in a combustion charge. Related apparatus and control logic is also disclosed. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895549 |
| CURRENT CPC | Controlling Combustion Engines F02D 19/021 (20130101) F02D 19/081 (20130101) F02D 19/0615 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068418 | Loetz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Caterpillar Inc. (Peoria, Illinois) |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Andrew Joseph Loetz (West Lafayette, Indiana); Jaswinder Singh (Dunlap, Illinois); David Todd Montgomery (Edelstein, Illinois) |
| ABSTRACT | Operating a gaseous fuel engine system includes conveying hydrogen fuel and hydrocarbon fuel into a cylinder in a gaseous fuel engine for combustion. Operating a gaseous fuel engine system further includes receiving an increased engine power output request, boosting a power output of the gaseous fuel engine by varying a ratio of the hydrogen fuel and the hydrocarbon fuel combusted in the cylinder, and varying an in-cylinder combustion parameter based on the varying a ratio. Perturbation to a performance profile of the gaseous fuel engine is thereby limited. Related apparatus and control logic is also disclosed. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895551 |
| CURRENT CPC | Controlling Combustion Engines F02D 19/081 (20130101) Original (OR) Class F02D 19/0602 (20130101) F02D 19/0644 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068913 | Van Zile et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Van Zile (Columbus, Ohio); Lei Raymond Cao (Columbus, Ohio); Andrew Kauffman (Columbus, Ohio) |
| ABSTRACT | An example extraction system includes a main body having a collar coupler for coupling to a pierceable portion of a container such that the first channel is in fluid communication with the pierceable portion when the container is coupled to the coupler, where the second body end defines a second channel extending such that the second channel is in fluid communication with the first channel; and a piston defining a piston channel extending from the first piston end to the second piston end, the piston including a hollow needle fluid communication with the piston channel, where the piston is slidably disposable within the second channel such that the hollow needle of the piston can extend through the first channel to pierce the pierceable portion of the container such that the container is in fluid communication through the hollow needle, the piston channel, and the second channel. |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/456656 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/14 (20130101) Original (OR) Class G01N 1/44 (20130101) G01N 2001/1037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069525 | Karandikar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jaydeep Karandikar (Oak Ridge, Tennessee); Junghoon Chae (Oak Ridge, Tennessee); Kevin Scott Smith (Oak Ridge, Tennessee); Tony Schmitz (Oak Ridge, Tennessee); Chad Steed (Oak Ridge, Tennessee) |
| ABSTRACT | Historical in-process machining information can be used to make machining process parameter recommendations. The disclosed systems and methods enable continuous learning for machining parameter selection using aggregated in-process machining information. The systems and methods save in-process machining data in a database using a standardized format, use data augmentation outlier detection, aggregation, and clustering algorithms to make machining process parameter recommendations and expected cut time predictions based on user inputs. The system can include a front-end dashboard to facilitate visualization and interpret results. |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/239438 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4155 (20130101) Original (OR) Class G05B 2219/33099 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069769 | Brewer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas) |
| ABSTRACT | Disclosed in some examples are methods, systems, memory devices, and machine-readable mediums that allow a memory device to efficiently mark memory extents involved in an enhanced memory operation. An extent is marked if a meta state associated with the extent indicates that the extent is included in the enhanced memory operation. The largest memory extents of the operation are maintained in the memory device as a list of unmarked extents. When a primitive memory operation is received, the memory address is compared to the unmarked extents in the list to the meta state for that memory line. If the address is covered by the list of extents, or that line's meta state is marked, then the memory operation is performed including the enhanced memory operation. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823470 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0619 (20130101) G06F 3/0631 (20130101) G06F 3/0634 (20130101) Original (OR) Class G06F 3/0644 (20130101) G06F 3/0673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069795 | Dugan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Keith Dugan (Richardson, Texas); Tony M. Brewer (Plano, Texas) |
| ABSTRACT | A system includes a host device having a first buffer with ordered data. An accelerator device has a data movement processor and a reordering buffer. A multiple-channel interface couples the host device and the data movement processor of the accelerator device. The data movement processor is configured to issue a read command for a portion of the ordered data. In coordination with issuing the read command, an entry of the reordering buffer is allocated. A transaction identifier for the read command is allocated. Unordered responses are received from the host device via the multiple-channel interface. The responses include respective portions of the ordered data and a respective transaction identifier. The responses are reordered in the reordering buffer based on the respective transaction identifiers and the allocated entry of the reordering buffer. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898929 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0656 (20130101) Original (OR) Class G06F 3/0659 (20130101) G06F 3/0673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069800 | Brewer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas); Dean E. Walker (Allen, Texas) |
| ABSTRACT | System and techniques for host-preferred memory operation are described herein. At a memory-side cache of a memory device that includes accelerator hardware, a first memory operation can be received from a host. A determination that the first memory operation corresponds to a cache set based on an address of the first memory operation is made. A second memory operation can be received from the accelerator hardware. Another determination can be made that the second memory operation corresponds to the cache set. Here, the first memory operation can be enqueued in a host queue of the cache set and the second memory operation can be enqueued in an internal request queue of the cache set. The first memory operation and the second memory operation can be executed as each is dequeued. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823314 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0607 (20130101) G06F 3/0659 (20130101) Original (OR) Class G06F 3/0679 (20130101) G06F 9/3877 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069801 | Brewer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas); Dean E. Walker (Allen, Texas) |
| ABSTRACT | Systems and techniques for a memory-side cache directory-based request queue are described herein. A memory request is received at an interface of a memory device. One or more fields of the memory request are written into an entry of a directory data structure. The identifier of the entry is pushed onto a queue. To perform the memory request, the identifier is popped off of the queue and a field of the memory request is retrieved from the entry of the directory data structure using the identifier. Then, a process on the memory request can be performed using the field retrieved from the entry of the directory data structure. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823391 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0659 (20130101) Original (OR) Class G06F 3/0679 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069802 | Brewer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas) |
| ABSTRACT | A method performed by a distributed computing system includes receiving a work packet from a separate computing device via a fabric interconnect at a command manager (CM) of a memory controller of a fabric attached memory (FAM) device, wherein the work packet includes a memory access to be performed by a FAM computing resource local to the FAM device; determining a work class of the work packet; placing the work packet in a CM work queue local to the CM for the work class when space is available in the CM work queue for the work class; and when the CM work queue for the work class is full, placing the work packet in a destination work queue according to an address included in the work packet, wherein the destination queue is implemented in a memory array of the FAM device external to the memory controller. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823462 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0611 (20130101) G06F 3/0658 (20130101) G06F 3/0659 (20130101) Original (OR) Class G06F 3/0679 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069804 | Brewer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas); Michael Keith Dugan (Richardson, Texas) |
| ABSTRACT | Host and accelerator devices can be coupled using various interfaces, such as Compute Express Link (CXL). In an example, user applications can have protected access to a shared set of control parameters for different queues. A protocol can allow an application to use a unique memory page at the accelerator device through which the application can access control parameters, such as can be used to control memory-based communication queues or other queues. In an example, there can be multiple sets of control parameters in a single memory page. The protocol can allow views of the single memory page from respective different application processes. In an example, the protocol can include or use an access check to detect and handle unauthorized accesses to particular parameters. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898803 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0622 (20130101) G06F 3/0659 (20130101) Original (OR) Class G06F 3/0679 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069805 | Dugan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Keith Dugan (Richardson, Texas); Tony M. Brewer (Plano, Texas) |
| ABSTRACT | A system includes a memory device and a command manager configured to reorder read requests. The command manager is configured to receive a read response associated with a transaction identifier for the read request. A free list entry for the read request is allocated from a free list. The free list entry is associated with a transaction identifier of the read request. A tail index of a reordering queue is written to a remapping queue based on the free list entry. The tail index is configured to provide a write address of the reordering queue that is allocated for the read request. A read response associated with the transaction identifier for the read request is received. The read response is written to the allocated entry of the reordering queue. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/899016 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0659 (20130101) Original (OR) Class G06F 3/0679 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069889 | Choi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sung Nam Choi (Sandia Park, New Mexico); John C. Pavlakos (Albuquerque, New Mexico); Neil Sparks (Albuquerque, New Mexico); Adrian R. Chavez (Davis, California); Alan Sonntag (Albuquerque, New Mexico); Florentino Barrientos (Albuquerque, New Mexico) |
| ABSTRACT | In an approach to secure firmware updating, a system comprises: one or more user devices, each of the one or more user devices having one or more firmware modules; one or more computing devices; a digital signature repository; and a z-engine circuitry. The z-engine circuitry is configured to: receive firmware for a particular user device of the one or more user devices; receive a non-repeating input data; retrieve a hardware digital profile of the particular user device from the digital signature repository; process the non-repeating input data with the hardware digital profile to generate a unique result; perform a hash operation on the unique result to generate an encryption key; encrypt the firmware for the particular user device with the encryption key; and send the encrypted firmware to the particular user device. |
| FILED | Thursday, August 24, 2023 |
| APPL NO | 18/237667 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/65 (20130101) Original (OR) Class G06F 21/572 (20130101) G06F 2221/033 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3239 (20130101) H04L 9/3247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240069984 — QUEUEING ASYNCHRONOUS EVENTS FOR ACCEPTANCE BY THREADS EXECUTING IN A BARREL PROCESSOR
| US 20240069984 | Baronne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Baronne (Allen, Texas); Tony M. Brewer (Plano, Texas) |
| ABSTRACT | Devices and techniques for asynchronous event message handing in a processor are described herein. A barrel multithreaded processor may include an asynchronous event handler to receive an indication of a thread create instruction from a parent thread, determine a return value size of return values from the indication of the thread create instruction, determine whether sufficient space exists in the memory to store the return values, allocate space in the memory to store the return parameters in response to determining that there is sufficient space in the memory to store the return values, and provide access to the return values from the allocated space to the parent thread based at least in part on a thread return instruction from the child thread. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823468 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) Original (OR) Class G06F 9/3009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070011 | Baronne |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Baronne (Allen, Texas) |
| ABSTRACT | Devices and techniques for parking threads in a barrel processor for managing hazard clearing are described herein. A barrel processor includes hazard management circuitry that is used to receive an indication of an instruction executing in a compute pipeline of the barrel processor, the instruction having encountered a hazard and unable to progress through the compute pipeline; store the indication of the instruction in a hazard memory; receive a signal indicating that the hazard has cleared; and cause the instruction to be rescheduled at the beginning of the compute pipeline in response to the signal. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/897926 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3861 (20130101) G06F 11/0721 (20130101) G06F 11/0793 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070060 | Brewer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas); Dean E. Walker (Allen, Texas) |
| ABSTRACT | System and techniques for synchronized request handling at a memory device are described herein. A request is received at the memory device. Here, the request indicates a memory address corresponding to a set of cache lines and a single cache line in the set of cache lines. The memory device maintains a deferred list for the set of cache lines and a set of lists with each member of the set of lists corresponding to one cache line in the set of cache lines. The memory device tests the deferred list to determine that the deferred list is not empty and places the request in the deferred list. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/899197 |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0238 (20130101) Original (OR) Class G06F 12/0833 (20130101) G06F 12/0893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070074 | Walker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dean E. Walker (Allen, Texas); Tony M. Brewer (Plano, Texas) |
| ABSTRACT | System and techniques for variable execution time atomic operations are described herein. When an atomic operation for a memory device is received, the run length of the operation is measured. If the run length is beyond a threshold, a cache line for the operation is locked while the operation runs. A result of the operation is queued until it can be written to the cache line. At that point, the cache line is unlocked. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/899184 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/345 (20130101) Original (OR) Class G06F 9/3004 (20130101) G06F 9/3816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070077 | Walker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dean E. Walker (Allen, Texas); Tony M. Brewer (Plano, Texas) |
| ABSTRACT | System and techniques for memory side cache request handling are described herein. When a memory request is received, a cache set for the memory request is determined. Here, the cache set has multiple ways and each way corresponds to a cache line. It can be detected that a way of the multiple ways is not ready for the memory request. In this case, a representation of the memory request is stored in a queue of multiple queues based on an interface upon which the memory request was received and the present ways of the cache set. Entries from the multiple queues can be dequeued in a defined order to determine a next memory request to process. The defined order gives priority to memory requests for a present way and then for external over internal requests. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823323 |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0855 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070078 | Walker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dean E. Walker (Allen, Texas); Tony M. Brewer (Plano, Texas) |
| ABSTRACT | System and techniques for recall pending cache line eviction are described herein. A queue that includes a deferred memory request is kept for a cache line. Metadata for the queue is stored in a cache line tag. When a recall is needed, the metadata is written from the tag to a first recall storage, referenced by a memory request ID. After the recall request is transmitted, the memory request ID is written to a second recall storage referenced by the message ID of the recall request. Upon receipt of a response to the recall request, the queue for the cache line can be restored by using the message ID in the response to lookup the memory request ID from the second recall storage, then using the memory request ID to lookup the metadata from the first recall storage, and then writing the metadata into the tag for the cache line. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/899171 |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0855 (20130101) Original (OR) Class G06F 12/0891 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070082 | Brewer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas); Dean E. Walker (Allen, Texas) |
| ABSTRACT | System and techniques for evicting a cache line with pending control request are described herein. A memory request—that includes an address corresponding to a set of cache lines—can be received. A determination can be made that a cache line of the set of cache lines will be evicted to process the memory request. Another determination can be made that a control request has been made to a host from the memory device and that the control request pending when it is determined that the cache line will be evicted. Here, a counter corresponding to the set of cache lines can be incremented (e.g., by one) to track the pending control request in face of eviction. Then, the cache line can be evicted. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823307 |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0891 (20130101) Original (OR) Class G06F 2212/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070083 | Brewer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas); Dean E. Walker (Allen, Texas) |
| ABSTRACT | System and techniques for silent cache line eviction are described herein. A memory device receives a memory operation from a host. The memory operation establishes data and metadata in a cache line of the memory device upon receipt. The metadata is stored in a memory element that corresponds to the cache line. Later, an eviction trigger to evict the cache line is identified. Then, in response to the eviction trigger, current metadata of the cache line is compared with the metadata in the memory element to determine whether the metadata has changed. the cache line can be evicted without writing to backing memory in response to the metadata being unchanged. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823408 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3816 (20130101) G06F 12/0891 (20130101) Original (OR) Class G06F 2212/7209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070088 | Baronne |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Baronne (Allen, Texas) |
| ABSTRACT | Devices and techniques for parking threads in a barrel processor for managing cache eviction requests are described herein. A barrel processor includes eviction circuitry and is configured to perform operations to: (a) detect a thread that includes a memory access operation, the thread entering a memory request pipeline of the barrel processor; (b) determine that a data cache line has to be evicted from a data cache for the thread to perform the memory access operation; (c) copy the thread into a park queue; (d) evict a data cache line from the data cache; (e) identify an empty cycle in the memory request pipeline; (f) schedule the thread to execute during the empty cycle; and (g) remove the thread from the park queue. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/897913 |
| CURRENT CPC | Electric Digital Data Processing G06F 12/126 (20130101) Original (OR) Class G06F 2212/1044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070838 | Smoqi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ziyad Smoqi (Lincoln, Nebraska); Prahalada Rao (Lincoln, Nebraska); Benjamin Bevans (Lincoln, Nebraska); Aniruddha Gaikwad (Lincoln, Nebraska) |
| ABSTRACT | Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for detection of defects in additive manufacturing. In some implementations, a method includes obtaining an image representing a volume of molten material; extracting one or more features from the image; providing the one or more features to a trained machine learning model; obtaining output from the trained machine learning model; and determining, using the output, a defect in a part. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/240879 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 12/90 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) Image Data Processing or Generation, in General G06T 7/0004 (20130101) Original (OR) Class G06T 2207/20081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072217 | CHEREPY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Current Lighting Solutions, LLC (Cleveland, Ohio) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Current Lighting Solutions, LLC (Cleveland, Ohio) |
| INVENTOR(S) | Nerine CHEREPY (Piedmont, California); Ross Allen OSBORNE (Livermore, California); Stephen PAYNE (Castro Valley, California); Zachary SEELEY (Livermore, California); Alok SRIVASTAVA (Niskayuna, New York); William BEERS (Chesterland, Ohio); William COHEN (Solon, Ohio) |
| ABSTRACT | The present disclosure relates to a lighting component which may comprise a light emitting diode (LED) or laser diode (LD) for generating at least one of blue light or ultraviolet light. A fluoride phosphor matrix may be included, which may be consolidated into a phosphor ceramic structure including at least one of a transparent fluoride ceramic structure or a translucent fluoride ceramic structure, and positioned adjacent to the LED or LD. The phosphor ceramic structure generates at least one of red or orange light when irradiated by the light emitted from the LED or LD. The phosphor ceramic structure exhibits reduced thermal quenching relative to a fluoride particulate structure irradiated by the LED or LD. |
| FILED | Tuesday, November 07, 2023 |
| APPL NO | 18/387630 |
| CURRENT CPC | Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for F21K 9/64 (20160801) F21K 9/90 (20130101) Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2115/30 (20160801) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/0095 (20130101) H01L 33/504 (20130101) Original (OR) Class H01L 33/641 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072231 | Cardenas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jorge Antonio Cardenas (Albuquerque, New Mexico); John Paul Bullivant (Albuquerque, New Mexico); Katharine Lee Harrison (Albuquerque, New Mexico); Adam W. Cook (Albuquerque, New Mexico); Albert Alec Talin (Dublin, California) |
| ABSTRACT | Custom-form batteries can supply complex, practical systems with an optimal energy density that wouldn't otherwise be possible using traditional battery form-factors. For example, iron disulfide (FeS2) is a prominent conversion cathode of commercial interest. 3D direct-ink write (DIW) printing of FeS2 inks can be used to produce ridged cathodes from the filamentary extrusion of highly concentrated FeS2 inks (60-70% solids). These ridged cathodes exhibit optimal power, uniformity, and stability when cycled at higher rates (in excess of C/10). Meanwhile, functional cells with custom-form wave-shaped electrodes (e.g., printed FeS2 cathodes and pressed lithium anodes) exhibit improved performance over similar cells in planar configurations. In general, the DIW of concentrated inks is a viable path toward the making of custom-form conversion lithium batteries. More broadly, ridging is found to optimize rate capability. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895285 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/139 (20130101) H01M 4/0404 (20130101) Original (OR) Class H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072256 | BECKNELL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nigel BECKNELL (Glen Ellyn, Illinois); PIETRO PAPA LOPES (Woodridge, Illinois) |
| ABSTRACT | Described herein is crystalline PbSO4 comprising tabular and/or diamond-shaped crystals having an average crystal size, as determined by dynamic light scattering and particle imaging using a transmission electron microscope, in the range of about 10 nm to about 2 μm, wherein at least about 80% of the PbSO4 crystals have diameters within about ±20% of the average diameter. Also described herein electrodes, lead-acid electrochemical cells, and lead-acid batteries comprising the crystalline PbSO4. |
| FILED | Thursday, August 25, 2022 |
| APPL NO | 17/895840 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/20 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/60 (20130101) C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2004/04 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/56 (20130101) H01M 4/73 (20130101) H01M 4/625 (20130101) H01M 4/627 (20130101) H01M 4/5825 (20130101) Original (OR) Class H01M 10/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072449 | Byers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyle J. Byers (Kansas City, Missouri); Louis Brown (Kansas City, None); Daniel John Salzman (Kansas City, Missouri) |
| ABSTRACT | A method of tuning an electrically small antenna comprising a radiating element and a support structure comprises applying a force to the support structure to change a shape or a dimension of the radiating element to increase or decrease a frequency at which the electrically small antenna resonates. |
| FILED | Monday, October 09, 2023 |
| APPL NO | 18/483188 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/36 (20130101) H01Q 9/14 (20130101) Original (OR) Class H01Q 9/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072515 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xuedan Ma (Woodridge, Illinois); Jia-Shiang Chen (Downers Grove, Illinois); Mark Hersam (Evanston, Illinois); Anushka Dasgupta (Evanston, Illinois) |
| ABSTRACT | Optical gain media and gain devices are required for lasing devices and high intensity optical systems across a wide range of application. A compact optical gain device that provides near-infrared and infrared lasing at room temperature includes an optical microcavity having a refractive index and a curvilinear outer surface with an angle of curvature such that the optical microcavity supports the propagation of an electromagnetic whispering gallery mode. A plurality of optical gain structures are disposed along the curvilinear outer surface of the optical microcavity, the each of the optical gain structures having an optically active wavelength range over which each of the corresponding optical gain structures provides optical gain to radiation through stimulated emission. |
| FILED | Tuesday, August 23, 2022 |
| APPL NO | 17/894009 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/204 (20130101) H01S 5/1067 (20130101) H01S 5/02407 (20130101) H01S 5/06804 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072637 | Du et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | BOARD OFTRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| INVENTOR(S) | Xia Du (Fayetteville, Arkansas); Liyang Du (Fayetteville, Arkansas); Andrea Stratta (Fayetteville, Arkansas); Asif Faruque (Fayetteville, Arkansas); H. Alan Mantooth (Fayetteville, Arkansas); Yuqi Wei (Fayetteville, Arkansas) |
| ABSTRACT | A multiphase converter for reducing the input and output current ripples. The multiphase converter includes a system controller and power devices. Furthermore, the multiphase converter includes an active gate driver integrated circuit (IC) electrically connected to the system controller and the power devices. The active gate driver IC receives signals from the system controller and provides outputs to the power devices based, at least in part, on real-time feedback from the power devices. |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/238622 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/0009 (20210501) H02M 1/15 (20130101) H02M 1/084 (20130101) Original (OR) Class H02M 1/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240074218 | Forrest et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Xin Xiao (Ann Arbor, Michigan); Jeramy D. Zimmerman (Golden, Colorado); Kevin Bergemann (Ann Arbor, Michigan); Anurag Panda (Ann Arbor, Michigan); Brian E. Lassiter (San Francisco, California); Mark E. Thompson (Anaheim, California); Andrew N. Bartynski (Los Angeles, California); Cong Trinh (San Jose, California) |
| ABSTRACT | Disclosed herein are organic photosensitive devices including at least one exciton-blocking charge carrier filter. The filters comprise a mixture of at least one wide energy gap material and at least one electron or hole conducting material. As described herein, the novel filters simultaneously block excitons and conduct the desired charge carrier (electrons or holes). |
| FILED | Wednesday, March 15, 2023 |
| APPL NO | 18/184497 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Organic electric solid-state devices H10K 30/353 (20230201) Original (OR) Class H10K 85/211 (20230201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
20240065568 — ACOUSTEOMIC SENSING AND MONITORING USING A HUMAN-CENTRIC INTELLIGENT ACOUSTEOMIC ARRAY
| US 20240065568 | ANDREOU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Andreas G. ANDREOU (Baltimore, Maryland); Rajat MITTAL (Vienna, Virginia); Christos SAPSANIS (Patras, Greece); Jung Hee SEO (Baltimore, Maryland); W. Reid THOMPSON (Baltimore, Maryland); Jon R. RESAR (Stevenson, Maryland) |
| ABSTRACT | An appliance for monitoring blood flow is provided. The appliance includes a plurality of spatially separated acousteomic sensors for auscultation detection of a patient; a hardware processor and a non-transitory computer-readable medium that stores a trained computer model for modeling a function of a healthy heart for analyzing the acousteomic signals; and a transmitter that transmits the acousteomic signals from the plurality of acousteomic sensors. |
| FILED | Thursday, December 23, 2021 |
| APPL NO | 18/259345 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/026 (20130101) Original (OR) Class A61B 5/282 (20210101) A61B 5/6805 (20130101) A61B 2562/0204 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/20081 (20130101) G06T 2207/30048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240065839 | Pirozzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ileana Pirozzi (Palo Alto, California); Ali Kight (Palo Alto, California); Kyung Won Han (Stanford, California); Rohan Shad Arora (San Jose, California) |
| ABSTRACT | Devices and methods are provided for supporting a subject's heart, e.g., to support the left and/or right ventricles of the heart, e.g., to prevent and/or treat heart failure. In one example, the device includes a sleeve configured to be implanted over a region of the subject's heart including a lattice formed on a surface of the sleeve. The sleeve may be positioned and permanently implanted over a desired region of the subject's heart to provide passive support to ventricular tissue of the heart. |
| FILED | Saturday, September 30, 2023 |
| APPL NO | 18/375498 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2481 (20130101) Original (OR) Class A61F 2210/0057 (20130101) A61F 2210/0076 (20130101) A61F 2230/0019 (20130101) A61F 2240/007 (20130101) A61F 2240/008 (20130101) A61F 2250/0009 (20130101) A61F 2250/0012 (20130101) A61F 2250/0018 (20130101) A61F 2250/0028 (20130101) A61F 2250/0048 (20130101) A61F 2250/0096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066051 | LINHARDT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Robert John LINHARDT (Albany, New York); Fuming ZHANG (Watervliet, New York); Jawed FAREED (Westchester, Illinois); Walter JESKE (Woodridge, Illinois) |
| ABSTRACT | Prophylaxis and treatment of patients susceptible to infection by coronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is achieved using compositions including one or more inhibitors including sulfated glycans and/or highly negative charged compounds. The inhibitors bind to wild-type and variant spike glycoproteins (S-proteins or SGPs) of SARS-CoV-2, inhibiting fusion, entry, and infection of a host cell. The inhibitors can include pentosan polysulfate (PPS), mucopolysaccharide polysulfate (MPS), sulfated lactobionic acid, sulodexide, a defibrotide, 4-t-butylcalix[X] arene-p-sulfonic acid, or combinations thereof. The presence of additional sulfo groups in PPS and MPS contribute to the improved inhibitory activity of compositions with those sulfated glycans against COVID-19 compared with compositions containing heparin alone. The compositions can be formulated for nasal delivery to a patient, enabling a simplified treatment regimen effective against an ever increasing number of SARS-CoV-2 variants of concern. |
| FILED | Thursday, August 24, 2023 |
| APPL NO | 18/237624 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 31/737 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066119 | JEWELL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher M. JEWELL (Silver Spring, Maryland); James I. ANDORKO (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure relates to methods for eliciting an immune response to a cancer antigen in a subject in need thereof by introducing directly into at least one lymph node of the subject, and preferably at least two lymph nodes, a therapeutically effective amount of a cancer antigen and/or an adjuvant such that an immune response to the cancer antigen is activated or enhanced in the subject. The present disclosure also concerns pharmaceutical compositions that comprise a therapeutically effective amount of a cancer antigen and/or an adjuvant capable of mediating, and more preferably enhancing, activation of the immune system of a subject against cancer cells that are associated with any of a variety of cancers. The disclosure also relates to the use of such pharmaceutical compositions in the treatment or prevention of a cancer in a recipient subject. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 18/261146 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066572 | Campanella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut) |
| ABSTRACT | A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498770 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066573 | Campanella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut) |
| ABSTRACT | A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498869 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066593 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lianyi Chen (Madison, Wisconsin); Ali Nabaa (Madison, Wisconsin) |
| ABSTRACT | Aspects of the disclosure are directed to methods and/or apparatuses involving the formation of pore-free or nearly pore-free liquid droplets. As may be implemented in accordance with one or more embodiments, liquid droplets including metal are formed having pores within the liquid droplets. This may involve, for example, atomizing liquid metal with a gas and forming the droplets having pores. The pores are then driven out of the liquid droplets by heating the liquid droplets from a first state in which an outer surface of the droplets has a lower temperature than an inner region thereof, to a second state in which the outer surface has a higher temperature than the inner region. |
| FILED | Tuesday, August 23, 2022 |
| APPL NO | 17/893874 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/082 (20130101) Original (OR) Class B22F 2009/086 (20130101) B22F 2301/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067843 | Deng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | South Dakota Board of Regents (Pierre, South Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ying Deng (Sioux Falls, South Dakota); Shahaboddin Saeedi (Canton, South Dakota); Victor Huber (Dakota Dunes, South Dakota) |
| ABSTRACT | The present disclosure is directed to compositions, methods, and treated surfaces that comprise a co-polymer composition comprising a rechargeable N-halamine moiety and one or more monomers. The compositions are pre-halogenated for providing a single step application for antimicrobial use without the need for a subsequent chlorine application for activation of antimicrobial properties. The copolymers provide for effective and rapid inactivation of bacteria and viruses, with improved solubility and stability. |
| FILED | Wednesday, August 16, 2023 |
| APPL NO | 18/450891 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/34 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/004 (20130101) C09D 5/14 (20130101) C09D 7/65 (20180101) C09D 133/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068451 | Acome et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Artimus Robotics Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | Artimus Robotics Inc. (Boulder, Colorado) |
| INVENTOR(S) | Eric Lucas Acome (Longmont, Colorado); Nicholas Alexander Kellaris (Boulder, Colorado); Shane Karl Mitchell (Boulder, Colorado); Jennifer Lyn Vigil (Boulder, Colorado) |
| ABSTRACT | An actuator system includes an actuator with a deformable shell defining a pouch, a fluid dielectric contained within the pouch, and first and second electrodes disposed over opposing sides of the pouch, each electrode having two long edges and two short edges. The system also includes a power source for providing a voltage between the electrodes. The electrodes cover 50 to 90% of the first and second sides, respectively, of the pouch, and a gap is defined between long edges of the pouch and the electrodes such that, upon application of the voltage at one of the short edges of the electrodes, respectively, the electrodes selectively zip together from the one of the short edges toward an opposing one of the short edges. The system may also include a support structure for enabling the actuator to maintain its shape regardless of the voltage provided by the power source. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/237388 |
| CURRENT CPC | Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/008 (20210801) Original (OR) Class Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068823 | Ravishankar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chinya V. Ravishankar (Irvine, California); Payas Rajan (Riverside, California) |
| ABSTRACT | A vehicle path routing method is disclosed for determining a lowest-cost path from a source to a destination. A graph representing a road network includes vertices and edges between vertices. Vertices in the graph represent locations and edges represent paths between locations. Edge weights represent costs, such as travel times and energy consumptions for travel along edges of the graph. Significantly, edge weights are represented as probability distributions. The routing method partitions the edges into multiple tiers, for which convolutions of probability distributions can and cannot be feasibly replaced with functional approximations. A Dijkstra search of the graph from a vehicle origin to a vehicle destination computes, for vertices along a path, convolutions of distributions and sums of functional approximations. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/237136 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3446 (20130101) Original (OR) Class G01C 21/3453 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068965 | ROS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandra ROS (Phoenix, Arizona); Daihyun KIM (Mesa, Arizona); Austin ECHELMEIER (Tempe, Arizona); Jorvani CRUZ VILLARREAL (Tempe, Arizona); Ana EGATZ-GOMEZ (Phoenix, Arizona); Sebastian QUINTANA (Phoenix, Arizona) |
| ABSTRACT | Methods and systems are provided for serial femtosecond crystallography for reducing the vast amount of waste of injected crystals practiced with traditional continuous flow injections. A micrometer-scale 3-D printed water-in-oil droplet generator device includes an oil phase inlet channel, an aqueous phase inlet channel, a droplet flow outlet channel, and two embedded non-contact electrodes. The inlet and outlet channels are connected internally at a junction. The electrodes comprise gallium metal injected within the 3-D printed device. Voltage across the electrodes generates water-in-oil droplets, determines a rate for a series of droplets, or triggers a phase shift in the droplets. An external trigger generates the droplets based on the frequency of an XFEL utilized in droplet detection, thereby synchronizing a series of droplets with x-ray pulses for efficient crystal detection. The generated droplets can be coupled to an SFX with XFEL experiment compatible with common liquid injector such as a GDVN. |
| FILED | Tuesday, November 07, 2023 |
| APPL NO | 18/504091 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0241 (20130101) B01L 3/50273 (20130101) B01L 2300/0867 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20025 (20130101) Original (OR) Class G01N 2223/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068982 | BEYENAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Haluk BEYENAL (Pullman, Washington); Abdelrhman MOHAMED (Chicago, Illinois); Maren FRIESEN (Pullman, Washington) |
| ABSTRACT | A bioelectrochemical soil assessment method and system is disclosed, wherein electrical measurements provide distinct differences between healthy and unhealthy soils, and wherein the presence of microbes coupled to an electrode also indicates healthy soil but not for unhealthy soil. Moreover, a soil amendment solution addition stimulated current in both healthy and unhealthy soil, wherein the electrical current is utilized as a proxy for microbial metabolic activity to distinguish healthy and unhealthy soil. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/454463 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/308 (20130101) G01N 27/3277 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069516 | Welch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory Welch (Orlando, Florida); Gerd Bruder (Orlando, Florida); Ryan Schubert (Orlando, Florida); Austin Erickson (Orlando, Florida) |
| ABSTRACT | The invention pertains to methods for monitoring the operational status of a home automation system through extrinsic visual and audible means. Initial training periods involve capturing image and audio data representative of nominal operation, which is then processed to identify operational indicators. Unsupervised machine learning models are trained with these indicators to construct a model of normalcy and identify expectation violations in the system's operational pattern. After meeting specific stopping criteria, real-time monitoring is initiated. When an expectation violation is detected, contrastive collages or sequences are generated comprising nominal and anomalous data. These are then transmitted to an end user, effectively conveying the context of the detected anomalies. Further features include providing deep links to smartphone applications for home automation configuration and the use of auditory scene analysis techniques. The invention provides a multi-modal approach to home automation monitoring, leveraging machine learning for robust anomaly detection. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/240731 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/0428 (20130101) Original (OR) Class G05B 2219/2642 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069544 | Yildirim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emre Yildirim (Tampa, Florida); Tansel Yucelen (Tampa, Florida) |
| ABSTRACT | Methods and systems for control of multiagent networks with misbehaving vehicles over directed network topologies are disclosed. The methods and systems include: identifying a plurality of possible misbehaving vehicles among a plurality of vehicles in the networked multiagent system, determining a directed sub-network of a subset of the plurality of vehicles based on a first directed communication path of a first possible misbehaving vehicle of the plurality of possible misbehaving vehicles to a first vehicle and a second directed communication path of a driver vehicle of the plurality of vehicles to the first vehicle; and implementing a proportional-integral controller for suppressing an effect of the misbehaving vehicle on the networked multiagent system. Other aspects, embodiments, and features are also claimed and described. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/456444 |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0022 (20130101) G05D 1/0027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069962 | SHREVE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Matthew A. SHREVE (Campbell, California); Eric D. COCKER (Redwood City, California) |
| ABSTRACT | A method and system for implementing a task scheduler are provided in a resource constrained computation system that uses meta data provided for each task (e.g. data analysis algorithm or sensor sampling protocol) to determine which tasks should be run in a particular wake cycle, the order in which the tasks are run, and how the tasks are distributed across the available compute resources. When a task successfully completes, it's time of execution is logged in order to provide a reference for when that task should be run again. Task meta data is formatted in a manner to allow for simple integration of new tasks into the processing architecture. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898797 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3838 (20130101) G06F 9/4881 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070353 | WANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Haozhu WANG (Mount Prospect, Illinois); Lingjie Jay GUO (Ann Arbor, Michigan) |
| ABSTRACT | A computer system includes memory hardware configured to store a multitask neural network, an optimization model, a material database, material feature vector inputs, and computer-executable instructions which include training the multitask neural network with the material feature vector inputs to generate a material structural parameter output, obtaining at least one of a target optical perception parameter and a target optical response, supplying the target optical perception parameter or target optical response and at least two of the multiple material data structures of the material database to the multitask neural network to output the at least one predicted material and the predicted structural parameter distribution, processing, by the optimization model, the predicted structural parameter distribution to generate a tuned structural parameter output, and transmitting the at least one predicted material and the tuned structural parameter output to a computing device to facilitate generation of an optical structure. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/237993 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/27 (20200101) Original (OR) Class G06F 2111/06 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070451 | ZHANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert Bosch GmbH (Stuttgart, Germany) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jingyang ZHANG (Durham, North Carolina); Chaithanya Kumar MUMMADI (Pittsburgh, Pennsylvania); Wan-Yi LIN (Wexford, Pennsylvania); Ivan BATALOV (Pittsburgh, Pennsylvania); Jeremy KOLTER (Pittsburgh, Pennsylvania) |
| ABSTRACT | A computer-program product storing instructions which, when executed by a computer, cause the computer to receive an input data from a sensor, generate a training data set utilizing the input data, wherein the training data set is created by creating one or more copies of the input data and adding noise to the one or more copies, send the training data set to a diffusion model, wherein the diffusion model is configured to reconstruct and purify the training data set by removing noise associated with the input data and reconstructing the one or more copies of the training data set to create a modified input data set, send the modified input data set to a fixed classifier, and output a classification associated with the input data in response to a majority vote of the classification obtained by the fixed classifier of the modified input data set. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/900343 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/30 (20220101) G06V 10/82 (20220101) G06V 10/764 (20220101) G06V 10/774 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240070838 | Smoqi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ziyad Smoqi (Lincoln, Nebraska); Prahalada Rao (Lincoln, Nebraska); Benjamin Bevans (Lincoln, Nebraska); Aniruddha Gaikwad (Lincoln, Nebraska) |
| ABSTRACT | Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for detection of defects in additive manufacturing. In some implementations, a method includes obtaining an image representing a volume of molten material; extracting one or more features from the image; providing the one or more features to a trained machine learning model; obtaining output from the trained machine learning model; and determining, using the output, a defect in a part. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/240879 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 12/90 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) Image Data Processing or Generation, in General G06T 7/0004 (20130101) Original (OR) Class G06T 2207/20081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240071009 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| INVENTOR(S) | Yiqin Zhao (Sunnyvale, California); Tian Guo (North Grafton, Massachusetts) |
| ABSTRACT | In a mobile computerized device, a method for generating visually coherent lighting for mobile augmented reality comprises capturing a set of near-field observations and a set of far-field observations of an environment; generating an environment map based upon the set of near-field observations of the environment and the set of far-field observations of the environment; applying the environment map to a virtual object to render a visually-coherent virtual object; and displaying an image of the environment and the visually-coherent virtual object within the environment on a display of the mobile computerized device. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/237095 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 19/006 (20130101) Original (OR) Class G06T 2207/10024 (20130101) G06T 2207/10028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240071055 | Welch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory Welch (Orlando, Florida); Gerd Bruder (Orlando, Florida); Ryan Schubert (Orlando, Florida); Austin Erickson (Orlando, Florida) |
| ABSTRACT | The invention pertains to methods for monitoring the operational status of a home automation system through extrinsic visual and audible means. Initial training periods involve capturing image and audio data representative of nominal operation, which is then processed to identify operational indicators. Unsupervised machine learning models are trained with these indicators to construct a model of normalcy and identify expectation violations in the system's operational pattern. After meeting specific stopping criteria, real-time monitoring is initiated. When an expectation violation is detected, contrastive collages or sequences are generated comprising nominal and anomalous data. These are then transmitted to an end user, effectively conveying the context of the detected anomalies. Further features include providing deep links to smartphone applications for home automation configuration and the use of auditory scene analysis techniques. The invention provides a multi-modal approach to home automation monitoring, leveraging machine learning for robust anomaly detection. |
| FILED | Wednesday, September 06, 2023 |
| APPL NO | 18/461746 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/0428 (20130101) Original (OR) Class G05B 2219/2642 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240071779 | Levy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MOSAIC MICROSYSTEMS LLC (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Howard Levy (Rochester, New York); Shelby Forrester Nelson (Pittsford, New York) |
| ABSTRACT | A method of facilitating formation of a via in an inorganic substrate may include applying a single-sided acidic wet etching process to a first surface of the inorganic substrate in a first state in which the inorganic substrate has a mask layer set covering a second surface of the inorganic substrate; and applying a double-sided acidic wet etching process to the first surface and the second surface of the inorganic substrate after completion of the single-sided acidic wet etching process and in a second state in which the inorganic substrate has had the mask layer set removed from the second surface of the inorganic substrate. |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/383231 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/486 (20130101) Original (OR) Class H01L 23/15 (20130101) H01L 23/49827 (20130101) H01L 23/49838 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072569 | Nock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Destenie Nock (Pittsburgh, Pennsylvania); Shuchen Cong (Pittsburgh, Pennsylvania); Yueming Qiu (College Park, Maryland) |
| ABSTRACT | Provided is a system, method, and device for automated energy remediation. The system includes at least one processor programmed or configured to: store energy usage data for a plurality of households, store environmental data associated with the plurality of households, the environmental data including outdoor temperature measurements, determine an inflection temperature for each household of the plurality of households based on a nonlinear regression model, determine a gap metric value based on a maximum median inflection temperature and a minimum inflection temperature from the plurality of households, form a plurality of groups based on the plurality of households and household data associated with each household, each group including a subset of households of the plurality of households, determine at least one group of the plurality of groups, and automatically initiate at least one energy protocol for households in the at least one group. |
| FILED | Tuesday, August 22, 2023 |
| APPL NO | 18/236530 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/0012 (20200101) H02J 13/00002 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072991 | TORRES et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Francisco E. TORRES (San Jose, California); Eric D. COCKER (Redwood City, California) |
| ABSTRACT | A system and method are provided wherein encrypted data is stored in modular lockers on a first storage volume associated with a high-power microprocessor deployed in a system. Each encrypted locker maps, for example, to a specific time segment (e.g., one day) which simplifies mounting of the encrypted volume for data access and reduces the locker size for external access of data while encrypted (e.g., via Wifi). New data in a second storage volume associated with and generated by a low-power microprocessor associated with the system gets transferred to the encrypted data store during wake cycles of the high-power microprocessor. To manage space on the first storage volume, time stamps associated with each encrypted locker allows simple removal of files older than a specified time period by removing of any encrypted lockers older than that threshold. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898826 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/16 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) Original (OR) Class H04L 2209/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240073069 | Mangal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vivek Mangal (Santa Clara, California); Peter R. Kinget (Summit, New Jersey) |
| ABSTRACT | Circuit for wake-up receivers are provide. In some embodiments, the wake-up receivers include self-mixers that receive a gate bias voltage. Some of the self-mixers are single ended and some are differential. In some embodiments, the wake-up receivers include a matching network that is connected to the input of the self-mixer. In some embodiments, the wake-up receivers include a low frequency path connected to the output of the self-mixer. In some embodiments, the wake-up receivers include a high frequency path connected to the output of the self-mixer. In some embodiments, the wake-up receivers are configured to receive an encoded bit stream. In some embodiments, the wake-up receivers are configured to wake-up another receiver. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/383797 |
| CURRENT CPC | Pulse Technique H03K 19/0185 (20130101) H03K 19/17788 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/06 (20130101) Original (OR) Class H04L 27/2617 (20130101) H04L 27/26412 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240073152 | COCKER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Eric D. COCKER (Redwood City, California); Matthew A. SHREVE (Campbell, California); Francisco E. TORRES (San Jose, California) |
| ABSTRACT | A system and method provide a combination of a modular message structure, a priority-based message packing scheme, and a data packet queue management system to optimize the information content of a transmitted message in, for example, the Ocean of Things (OoT) environment. The modular message structure starts with a header that provides critical information and reference points for time and location. The rest of the message is composed of modular data packets, each of which has a data ID section that the message decoder uses for reference when reconstructing the message contents, an optional size section that specifies the length of the following data section if it can contain data of variable length, and a data section that can be compressed in a manner unique to that data type. The message packing scheme uses a combination of priority level and minimum reporting interval, both of which are dynamically configurable for each data packet type, to maximize the value of the information contained in the modular data packets included in each message. Finally, the data packet queues manage temporary storage of data packets that have been generated but not yet included in an outgoing message. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898985 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/06 (20130101) H04L 47/564 (20130101) H04L 47/6275 (20130101) Original (OR) Class H04L 69/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240073658 | SONG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Korea National University of Transportation Industry-Academic Corporation Foundation (Chungju-si, South Korea) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chang Ick SONG (Chungju-si, South Korea); Ju Hyeok KIM (Chungju-si, South Korea) |
| ABSTRACT | A method and a device for V2X communication channel estimation are disclosed. The V2X communication channel estimation according to an embodiment of the present disclosure may include calculating a first channel estimation value in a time-axis forward direction from a first midamble and a second channel estimation value in a time-axis backward direction from a second midamble located after the first midamble, based on a data pilot aided (DPA) channel estimation algorithm that uses a channel estimation value of a previous OFDM symbol to iteratively update a channel estimation value, and estimating, based on the first channel estimation value and the second channel estimation value, a final channel value of a specific OFDM symbol located between the first midamble and the second midamble. |
| FILED | Tuesday, August 22, 2023 |
| APPL NO | 18/236920 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0007 (20130101) H04L 5/0048 (20130101) Wireless Communication Networks H04W 4/40 (20180201) Original (OR) Class H04W 72/0446 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240074332 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Judy Z. Wu (Lawrence, Kansas); Ryan W. Goul (Topeka, Kansas) |
| ABSTRACT | Memristors are provided, which, in embodiments, comprise a bottom electrode; a top electrode in electrical communication with the bottom electrode, wherein one or both of the bottom and top electrodes is a Schottky electrode; and a dielectric stack between the bottom and top electrodes, the dielectric stack forming a top interface with a bottom surface of the top electrode and a bottom interface with a top surface of the bottom electrode, the dielectric stack comprising a plurality of atomic layer deposition (ALD)-grown atomic sublayers, the plurality comprising an ALD-grown atomic sublayer of a first metal oxide and an ALD-grown atomic sublayer of a second metal oxide. The second metal oxide is different from the first metal oxide and has a greater concentration of oxygen vacancies (VO) than the first metal oxide. The dielectric stack has a thickness of no more than about 5 nm. |
| FILED | Tuesday, May 31, 2022 |
| APPL NO | 18/280305 |
| CURRENT CPC | Electronic Memory Devices H10B 63/80 (20230201) Electric solid-state devices not otherwise provided for H10N 70/023 (20230201) Original (OR) Class H10N 70/24 (20230201) H10N 70/041 (20230201) H10N 70/841 (20230201) H10N 70/8833 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240066828 | Kang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jin Ho Kang (Newport News, Virginia); Keith L. Gordon (Hampton, Virginia); Shella Ann Thibeault (Hampton, Virginia); Jeffrey A. Hinkley (Yorktown, Virginia) |
| ABSTRACT | A composite material may include a polymer resin layer; and a plurality of rigid plates to reinforce the polymer resin layer, each rigid plate of the plurality of rigid plates having a polygon shape with rigid sides. The plurality of rigid plates may be fabricated in a pattern in the polymer resin layer to form a plurality of hinges in the polymer resin layer between sides of the plurality of rigid plates, so that the composite is foldable at the plurality of hinges into a collapse state and expandable at the plurality of hinges to deploy into a structure. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/238137 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/085 (20130101) Original (OR) Class B32B 5/02 (20130101) B32B 9/005 (20130101) B32B 9/045 (20130101) B32B 27/08 (20130101) B32B 27/12 (20130101) B32B 27/38 (20130101) B32B 2260/021 (20130101) B32B 2260/046 (20130101) B32B 2307/7376 (20230501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066836 | Kang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jin Ho Kang (Newport News, Virginia); Keith L. Gordon (Hampton, Virginia); Grace A. Belancik (Sunnyvale, California); Pranav Tolaram Jagtap (San Jose, California) |
| ABSTRACT | Described herein are highly thermally conductive hybrid carbon fiber composites. The composites are composed of one or more alternating layers of (a) a pyrolytic graphite sheet and (b) carbon fibers impregnated with a resin. The thermal conductivity of the composites is substantially higher when compared independently to the pyrolytic graphite sheet and carbon fibers. In addition to increased thermal conductivity, the composites possess other desirable properties such as increased thermal emissivity and solar absorptivity. The enhanced properties of the composites make them suitable for use in a number of different applications where heat flow is desirable. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/222126 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/266 (20130101) B32B 5/024 (20130101) B32B 7/12 (20130101) B32B 7/027 (20190101) B32B 9/007 (20130101) B32B 9/045 (20130101) B32B 9/047 (20130101) Original (OR) Class B32B 27/12 (20130101) B32B 37/06 (20130101) B32B 37/182 (20130101) B32B 38/04 (20130101) B32B 2038/047 (20130101) B32B 2260/021 (20130101) B32B 2260/046 (20130101) B32B 2262/106 (20130101) B32B 2305/076 (20130101) B32B 2307/54 (20130101) B32B 2307/72 (20130101) B32B 2307/302 (20130101) B32B 2307/7376 (20230501) B32B 2310/14 (20130101) B32B 2310/0831 (20130101) B32B 2313/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068453 | CHARI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California); The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Celia S. CHARI (Pasadena, California); Katherine T. FABER (Pasadena, California); Bryan W. McENERNEY (Pasadena, California); Richard R. HOFER (Pasadena, California); James A. WOLLMERSHAUSER (Alexandria, Virginia); Edward P. GORZKOWSKI, III (Severna Park, Maryland) |
| ABSTRACT | Aspects disclosed herein include graphite and hexagonal boron nitride bimaterials, methods of making these bimaterials, and electric propulsion devices or thrusters with these bimaterials. Aspects disclosed herein include electric propulsion devices comprising: at least one portion comprising or formed of a monolithic bimaterial; wherein the monolithic bimaterial comprises a graphite material and a hexagonal boron nitride material; and wherein the graphite material and hexagonal boron nitride material are monolithically integrated in the bimaterial. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/238101 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/413 (20230801) Non-metallic Elements; Compounds Thereof; C01B 32/21 (20170801) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068665 | Dai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RTX Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Zhongtao Dai (West Hartford, Connecticut); Lance L. Smith (West Hartford, Connecticut); Jeffrey M. Cohen (Hebron, Connecticut) |
| ABSTRACT | A main mixer including a swirler along an axis, the swirler including an outer swirler with a multiple of outer vanes, and a center swirler with a multiple of center vanes and a swirler hub along the axis, the swirler hub including a fuel manifold and an inner swirler with a multiple of inner vanes that support a centerbody, the multiple of inner vanes interconnect the fuel manifold and the centerbody. |
| FILED | Friday, October 06, 2023 |
| APPL NO | 18/377406 |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/14 (20130101) F23R 3/286 (20130101) Original (OR) Class F23R 2900/03041 (20130101) F23R 2900/03042 (20130101) F23R 2900/03044 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068720 | Stautner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ernst Wolfgang Stautner (Niskayuna, New York); Constantinos Minas (Slingerlands, New York) |
| ABSTRACT | Methods, apparatus, systems, and articles of manufacture are disclosed herein that include a cryogenic pump system comprising: a cryogenic liquid tank; a cryogenic pump including a suction adapter, the suction adapter connected to the cryogenic liquid tank via a liquid supply line and a gaseous return line; and a phase separator connected downstream of the cryogenic liquid tank and upstream of the cryogenic pump, the phase separator including a filtration structure integrated into the liquid supply line to separate vapor from cryogenic liquid, the phase separator connected to the gaseous return line to direct the vapor to the cryogenic liquid tank. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/900499 |
| CURRENT CPC | Separation B01D 19/0031 (20130101) B01D 19/0063 (20130101) B01D 39/2027 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/00 (20130101) F17C 2205/037 (20130101) F17C 2205/0338 (20130101) F17C 2205/0355 (20130101) F17C 2221/012 (20130101) F17C 2223/0161 (20130101) F17C 2227/0135 (20130101) F17C 2250/0434 (20130101) F17C 2250/0626 (20130101) F17C 2265/017 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 41/40 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068903 | Chen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pin-Chih Chen (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pin-Chih Chen (Scottsdale, Arizona) |
| ABSTRACT | This invention is a methodology, called CFD-based AIC generator, that can generate CFD-based structurally-independent Aerodynamic Influence Coefficient (AIC) matrices. Because the AIC matrices are independent of structure, they can be repeatedly used during the flight vehicle's structural design cycle for a fixed aerodynamic configuration to rapidly generate flutter, aeroservoelastic (ASE), and dynamic loads solutions. Inputs to processing include a CFD surface mesh, a coarsening ratio criterion, and a mid-layer panel model. The coarsening ratio criterion is computed from the CFD mesh. The mid-layer panel model is comprised of coarsened grid points derived from the CFD mesh and the coarsening ratio criterion. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/890805 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 9/08 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/15 (20200101) G06F 30/28 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240071349 | Shea, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Michael Shea, Jr. (Slidell, Louisiana); Alex McMullin (Athens, Alabama); Rosemarie Kathleen Sanders (Madison, Alabama); Gregory Allen Crum (Slidell, Louisiana); Kevin Alan Maurigi, Jr. (Bay St. Louis, Mississippi); Maurice Kyle Smith (Picayune, Mississippi) |
| ABSTRACT | A phased array ultrasonic testing device for positioning first and second phased array probes relative to a surface of a material to be tested. The testing device includes a first wedge configured to receive and orient the first phased array probe relative to the surface. A second wedge is configured to receive and orient the second phased array probe relative to the surface. A coupling structure is mounted to the first and second wedges and configured to selectively provide for the first and second wedges to move parallel to one another in a first direction and restrict relative movement of the first and second wedges in other directions. |
| FILED | Friday, November 05, 2021 |
| APPL NO | 17/520014 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/075 (20130101) G01N 29/262 (20130101) G01N 29/265 (20130101) G01N 2291/106 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/004 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20240065193 | Marks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); The Board of Trustees of Illinois State University (Normal, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael David Marks (Roseville, Minnesota); John C. Sedbrook (Bloomington, Illinois); Ratan Chopra (Minneapolis, Minnesota); Maliheh Esfahanian (Bloomington, Illinois) |
| ABSTRACT | This document relates to materials and methods for domesticating oilseed (e.g., pennycress) plants. For example, oilseed plants having reduced seedpod shatter, as well as materials and methods for making and using oilseed plants having reduced seedpod shatter are provided. |
| FILED | Thursday, April 20, 2023 |
| APPL NO | 18/137263 |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/20 (20180501) Original (OR) Class Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/24 (20130101) C12N 9/2402 (20130101) C12N 15/8213 (20130101) C12N 15/8266 (20130101) Enzymes C12Y 302/01015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068049 | VERMA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohit VERMA (West Lafayette, Indiana); Suraj MOHAN (San Jose, California); Ana PASCUAL-GARRIGOS (West Lafayette, Indiana); Haley BROUWER (Naples, Florida); Jennifer KOZIOL (Okmulgee, Oklahoma); Jon SCHOONMAKER (West Lafayette, Indiana); Timothy JOHNSON (West Lafayette, Indiana) |
| ABSTRACT | Assays, kits, and methods that target and/or detect the presence of bovine respiratory complex (BRD)-associated pathogens in a sample. These assays, kits and methods can be portable and capable of providing fast (within 45 minutes) and accurate (at least 96%) results in the field, eliminating the need for a laboratory and other complex equipment. |
| FILED | Thursday, November 11, 2021 |
| APPL NO | 18/252711 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068982 | BEYENAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Haluk BEYENAL (Pullman, Washington); Abdelrhman MOHAMED (Chicago, Illinois); Maren FRIESEN (Pullman, Washington) |
| ABSTRACT | A bioelectrochemical soil assessment method and system is disclosed, wherein electrical measurements provide distinct differences between healthy and unhealthy soils, and wherein the presence of microbes coupled to an electrode also indicates healthy soil but not for unhealthy soil. Moreover, a soil amendment solution addition stimulated current in both healthy and unhealthy soil, wherein the electrical current is utilized as a proxy for microbial metabolic activity to distinguish healthy and unhealthy soil. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/454463 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/308 (20130101) G01N 27/3277 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20240065792 | Beischel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government As Prepresented By The Department Of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles Beischel (Charleston, South Carolina); Nicole Beitenman (Charleston, South Carolina); Bethany Baldwin (Charleston, South Carolina); David Gatlin (Charleston, South Carolina); Jose Rodriguez (Charleston, South Carolina) |
| ABSTRACT | A surgical drape support for positioning on a patient's chest to support a drape above the patient's nose and mouth includes a main arch defining an inner main surface, an outer main surface, a main crown, a first main base edge, and a second main base edge. A first lower foot extends downward from the first main base edge and away from the outer main surface. A second lower foot extends downward from the second main base edge and away from the outer main surface. A first upper foot and a second upper foot extend upwards and away from the outer main surface to a position above the main crown. When the first lower foot and the second lower foot are positioned on the patient's chest they are configured to support the drape over the patient's nose and mouth. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/454373 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 46/20 (20160201) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0875 (20130101) A61M 2025/024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067926 | Siprashvili et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States Government as represented by the Department of Veterans Affairs (Washington, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zurab Siprashvili (San Mateo, California); Ngon T. Nguyen (Union City, California); M. Peter Marinkovich (Redwood City, California); Jean Tang (Stanford, California); Alfred T. Lane (Los Altos, California); Paul A. Khavari (Palo Alto, California) |
| ABSTRACT | Methods are provided for the cell-based delivery of collagen VII for the treatment of Epidermolysis Bullosa and corneal erosion. The disclosure also provides a composition and a pharmaceutical composition comprises, comprise, or alternatively consist essentially of, or yet further consist of a keratinocyte sheet or a corneal cell sheet. |
| FILED | Friday, November 03, 2023 |
| APPL NO | 18/501837 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) A61K 48/0075 (20130101) A61K 48/0091 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0629 (20130101) Original (OR) Class C12N 2510/00 (20130101) C12N 2760/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240067949 | CALDWELL |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); The US Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); The US Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Ruth CALDWELL (Augusta, Georgia) |
| ABSTRACT | Pathological retinal neovascularization is a common micro-vascular complication in several retinal diseases including retinopathy of prematurity (ROP), diabetic retinopathy, age related macular degeneration and central vein occlusion. Disclosed herein are compositions and methods useful for the treatment or prevention of retinal neovascularization and related diseases in a subject in need thereof. Exemplary methods include administering a composition including PEGylated arginase 1 to a subject in need thereof to promote reparative angiogenesis and decrease retinal neovascularization in the eye. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/350668 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20240066572 | Campanella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut) |
| ABSTRACT | A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498770 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240066573 | Campanella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut) |
| ABSTRACT | A control system for controlling extraction of landfill gas, comprising: at least one sensor configured to measure one or more characteristics of landfill gas; at least one flow control mechanism disposed in well piping and configured to control flow of the landfill gas through the well piping; and at least one processor configured to: obtain a measured concentration of a first gas in landfill gas; determine whether the measured concentration of the first gas is either less than a first threshold concentration or greater than a second threshold concentration; when it is determined that the measured concentration is less than the first threshold concentration, control the at least one flow control mechanism to reduce flow rate of landfill gas; and when it is determined that the concentration is greater than the second threshold concentration, control the at least one flow control mechanism to increase the flow rate of landfill gas. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498869 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240068903 | Chen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pin-Chih Chen (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pin-Chih Chen (Scottsdale, Arizona) |
| ABSTRACT | This invention is a methodology, called CFD-based AIC generator, that can generate CFD-based structurally-independent Aerodynamic Influence Coefficient (AIC) matrices. Because the AIC matrices are independent of structure, they can be repeatedly used during the flight vehicle's structural design cycle for a fixed aerodynamic configuration to rapidly generate flutter, aeroservoelastic (ASE), and dynamic loads solutions. Inputs to processing include a CFD surface mesh, a coarsening ratio criterion, and a mid-layer panel model. The coarsening ratio criterion is computed from the CFD mesh. The mid-layer panel model is comprised of coarsened grid points derived from the CFD mesh and the coarsening ratio criterion. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/890805 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 9/08 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/15 (20200101) G06F 30/28 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20240068990 | Chijioke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Akobuije Douglas Eziani Chijioke (Silver Spring, Maryland); Richard Albert Allen (Clarksburg, Maryland); Benjamin James Reschovsky (Cabin John, Maryland); Randall Paul Wagner (Arlington, Virginia) |
| ABSTRACT | A sound pressure metrology instrument determines sound pressure from index of refraction and includes: a light source that produces source light; the optical cavity that: receives an acoustic field from the sound source; receives the source light from the light source; produces acoustic-modified light from the source light; and communicates the acoustic-modified light to the photodetector; the photodetector that receives the acoustic-modified light from the optical cavity, produces an acoustic-modified signal from the acoustic-modified light, and communicates the acoustic-modified signal to the analyzer module; the analyzer module in electrical communication with the photodetector and that receives the acoustic-modified signal from the photodetector and determines the sound pressure of the acoustic field produced by the sound source from the modulations in the index of refraction of the acoustic medium inside the optical cavity encoded in the acoustic-modified light. % |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/239327 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/11 (20130101) Original (OR) Class G01N 29/2418 (20130101) G01N 2291/015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 20240068767 | VABNICK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federal Bureau of Investigation (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Federal Bureau of Investigation, Dept. of Justice (Washington, District of Columbia) |
| INVENTOR(S) | Ian B. VABNICK (Fredericksburg, Virginia); Lee R. Foltz (Indian Head, Maryland); Daniel E. McCarthy (La Plata, Maryland) |
| ABSTRACT | Provided herein are shaped-charges for focusing a filler, such as a fluid mass, and related methods of using the shaped-charges for disruption of an explosive target. The shaped-charge comprises an attenuating body positioned and configured to attenuate rarefaction waves to increase filler, including a fluid mass, explosively driven out of the container toward a target while also maintaining and enhancing fluid jet integrity. To further control impact and impulse forces on a target, additional layers may be used, including a foam layer and a jet-clipping layer positioned between the shaped-charge and the target surface. Also provided are propellant driven liquid disrupters having special attenuating bodies to improve liquid jet column characteristics. |
| FILED | Wednesday, December 28, 2022 |
| APPL NO | 18/090092 |
| CURRENT CPC | Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for F41B 9/0046 (20130101) Original (OR) Class Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 1/028 (20130101) F42B 1/032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20240073078 | JOHNSON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peraton Labs Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William JOHNSON (Basking Ridge, New Jersey); Kiran REGE (Basking Ridge, New Jersey); Achilles KOGIANTIS (Basking Ridge, New Jersey) |
| ABSTRACT | There is set forth herein, in one embodiment, receiving, by a transceiver of a UE device an aggregate signal stream, the aggregate signal stream including an aggregate of base station downlink signal streams from a plurality of base stations; and processing the aggregate signal stream. |
| FILED | Monday, November 06, 2023 |
| APPL NO | 18/502860 |
| CURRENT CPC | Transmission H04B 7/088 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/2657 (20130101) Original (OR) Class Wireless Communication Networks H04W 48/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Nuclear Regulatory Commission (NRC)
| US 20240066128 | GARNER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); Nanovis, LLC (Columbia City, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Allen Lawrence GARNER (West Lafayette, Indiana); Ram Anand VADLAMANI (West Lafayette, Indiana); David Alan DETWILER (Columbia City, Indiana) |
| ABSTRACT | Provided is a method of reducing a number of viable microbes, including contacting microbes with an antibiotic compound and applying pulses of electricity having a duration of between about 50 nanoseconds and about 900 nanoseconds. The pulses of electricity may have an intensity between about 20 kV/cm and about 40 kV/cm. The pulses of electricity may be applied at a frequency of between about 0.1 Hz and about 10 Hz. The microbes may be a gram-negative or a gram-positive strain of bacteria and the antibiotic may be applied at a concentration for a duration, wherein applying the antibiotic to the strain at the concentration for the duration does not reduce a viable number of bacteria of the strain as much, or at all, when the pulses of electricity are not also applied. |
| FILED | Thursday, October 19, 2023 |
| APPL NO | 18/490238 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/341 (20130101) A61K 31/496 (20130101) A61K 31/575 (20130101) A61K 31/702 (20130101) A61K 31/5377 (20130101) A61K 31/7048 (20130101) A61K 38/14 (20130101) A61K 41/0023 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20240069921 | Cline et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott Cline (Portland, Oregon); Robert Pawlowski (Beaverton, Oregon); Joshua Fryman (Corvallis, Oregon); Ivan Ganev (Portland, Oregon); Vincent Cave (Hillsboro, Oregon); Sebastian Szkoda (Gdansk, Poland); Fabio Checconi (Fremont, California) |
| ABSTRACT | Technology described herein provides a dynamically reconfigurable processing core. The technology includes a plurality of pipelines comprising a core, where the core is reconfigurable into one of a plurality of core modes, a core network to provide inter-pipeline connections for the pipelines, and logic to receive a morph instruction including a target core mode from an application running on the core, determine a present core state for the core, and morph, based on the present core state, the core to the target core mode. In embodiments, to morph the core, the logic is to select, based on the target core mode, which inter-pipeline connections are active, where each pipeline includes at least one multiplexor via which the inter-pipeline connections are selected to be active. In embodiments, to morph the core, the logic is further to select, based on the target core mode, which memory access paths are active. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/477884 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3885 (20130101) Original (OR) Class G06F 9/30036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20240070600 | Crone |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donald E. Crone (Frederick, Maryland) |
| ABSTRACT | An autonomous vehicle for delivery of items can detect its location and the location of targets on item receptacles in order to position the vehicle at a receptacle. The vehicle, in an autonomous mode, can automatically travel between delivery points along a delivery route. A presence sensor on the vehicle can detect ingress and egress from the vehicle to determine when the vehicle is ready to travel to the next delivery point. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/495643 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/047 (20130101) G06Q 10/083 (20130101) Original (OR) Class G06Q 10/08355 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20240069042 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NeuroQuest Ltd. (Misgav Business Park, Israel); Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science (Rehovot, Israel) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xin Huang (Mernda, Australia); Yihan Li (Parkville, Australia); James Doecke (Tamborine, Australia); Michal Eisenbach-Schwartz (Rehovot, Israel); Baijun Gu (Mernda, Australia) |
| ABSTRACT | Compositions and kits for diagnosing and prognosing Alzheimer's Disease (AD) in a human patient include a binding agent such as a monoclonal antibody for a biomarker conjugated to a detectable moiety such as a fluorophore, wherein the biomarker is chosen from CD11c, CD59, CD91, and CD163 and other phagocytosis-related molecules. Further compositions and kits employ panels of fluorophore-conjugated monoclonal antibodies for biomarkers including scavenger receptors. Methods for determining the relative expression of biomarkers, diagnosing AD, and determining the efficacy of AD therapeutic candidates such as phagocytosis-promoting agents and scavenger receptor agonists also appear. |
| FILED | Tuesday, November 07, 2023 |
| APPL NO | 18/387593 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/6896 (20130101) Original (OR) Class G01N 2800/2821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240069407 | Puckett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Matthew Wade Puckett (Phoenix, Arizona); Chad Fertig (Bloomington, Minnesota); Matthew Robbins (Minneapolis, Minnesota); Jad Salman (Wayzata, Minnesota) |
| ABSTRACT | A nonlinear wave mixing system with grating assisted phase matching is provided. The system includes a pump laser and a nonlinear waveguide. The pump laser is used to generate pump light at a select wavelength. The nonlinear waveguide is configured to generate produced light from the pump light that is directed into the nonlinear waveguide. The nonlinear waveguide includes at least one backward grating that is configured to diffract the produced light in a backward direction relative to a direction the produced light travels in the nonlinear waveguide to reach the backward grating. The backward grating having a grating momentum that generates counter-propagating phase matching in the produced light. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/900688 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3548 (20210101) Original (OR) Class G02F 1/3775 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0092 (20130101) H01S 3/109 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240072854 | ROBINSON |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rampart Communications, Inc. (Linthicum Heights, Maryland) |
| ASSIGNEE(S) | Rampart Communications, Inc. (Linthicum Heights, Maryland) |
| INVENTOR(S) | Matthew Brandon ROBINSON (Millersville, Maryland) |
| ABSTRACT | An apparatus includes a first communication device with multiple antennas, operably coupled to a processor and configured to access a codebook of transformation matrices. The processor generates a set of symbols based on an incoming data, and applies a permutation to each of the symbols to produce a set of permuted symbols. The processor transforms each of the permuted symbols based on at least one primitive transformation matrix, to produce a set of transformed symbols. The processor applies, to each of the transformed symbols, a precode matrix selected from the codebook of transformation matrices to produce a set of precoded symbols. The codebook of transformation matrices is accessible to a second communication device. The processor sends a signal to cause transmission, to the second communication device, of multiple signals, each representing a precoded symbol from the set of precoded symbols, each of the signals transmitted using a unique antenna from the plurality of antennas. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/495671 |
| CURRENT CPC | Transmission H04B 7/0456 (20130101) Original (OR) Class H04B 7/0491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240073885 | Stevens et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian W. Stevens (Elkridge, Maryland); Katherine M. Woolls (Baltimore, Maryland); Jacob M. Ray (Marriottsville, Maryland); Jared S. Everett (Washington, District of Columbia); Yongwen Yang (Columbia, Maryland); Benjamin E. Henty (Columbia, Maryland); Abdullahi A. Inshaar (Columbia, Maryland); Avik Dayal (Laurel, Maryland) |
| ABSTRACT | A method for determining control and scheduling information of a network includes receiving a radio frequency waveform having scrambled downlink control information (DCI), performing a cell search to determine cell identity information, performing a beam search and beam detection to estimate a signal quality of the waveform, decoding scheduling information associated with the waveform, detecting a control channel encoded with an unknown identity based on the scrambling identity and extracting resource elements of the control channel based on the scheduling information, attempting to decode the control channel via a re-encoding technique that is tested for accuracy and, in response to accuracy testing not passing, via a blind scrambling seed recovery technique, recovering the DCI based on the re-encoding technique or the blind scrambling seed recovery technique, and obtaining the control and scheduling information from the DCI. |
| FILED | Saturday, June 24, 2023 |
| APPL NO | 18/213822 |
| CURRENT CPC | Wireless Communication Networks H04W 72/232 (20230101) H04W 72/1263 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, February 29, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
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HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240229.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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