FedInvent™ Patent Applications
Application Details for Thursday, March 21, 2024
This page was updated on Tuesday, June 18, 2024 at 02:17 PM GMT
Department of Health and Human Services (HHS)
| US 20240090810 | Woody et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania); UPMC (PITTSBURGH, Pennsylvania); NORTHEASTERN UNIVERSITY (BOSTON, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania); UPMC (PITTSBURGH, Pennsylvania); NORTHEASTERN UNIVERSITY (BOSTON, Massachusetts) |
| INVENTOR(S) | Mary L. Woody (Pittsburgh, Pennsylvania); Murat Akcakaya (Pittsburgh, Pennsylvania); Sarah Ostadabbas (Watertown, Massachusetts); Rebecca Price (Pittsburgh, Pennsylvania); Xiaofei Huang (Lynnfield, Massachusetts); Richard T. Gall (Pittsburgh, Pennsylvania); Anna Wears (Pittsburgh, Pennsylvania); Nastasia O. McDonald (Pittsburgh, Pennsylvania); Jennifer Mak (Pittsburgh, Pennsylvania) |
| ABSTRACT | A neurofeedback system includes an EEG apparatus, a presentation apparatus and a controller. The controller is configured to: (i) cause the presentation apparatus to display an overlaid image to the user that comprises a first image flickering at a first frequency and a second image flickering at a second frequency different than the first frequency, the first image being an affective distractor stimulus image and the second image being a task-relevant stimulus image, (ii) receive from the EEG apparatus a number of first steady-state visual evoked potential (SSVEP) signals generated in response the first image of the overlaid image and a number of second SSVEP signals generated in response the second image of the overlaid image, and (iii) calculate feedback indicative of how much attention of the was user allocated to the task-relevant stimulus image versus how much attention of the user was allocated to the affective distractor stimulus image. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/469782 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/168 (20130101) Original (OR) Class A61B 5/378 (20210101) A61B 5/6803 (20130101) A61B 5/7257 (20130101) A61B 90/36 (20160201) A61B 2090/365 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240090817 | Weiss et al. |
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| FUNDED BY |
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| APPLICANT(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Shennan Aibel Weiss (Philadelphia, Pennsylvania); Zachary Waldman (Philadelphia, Pennsylvania); Michael Sperling (Philadelphia, Pennsylvania) |
| ABSTRACT | A device and a signal processing method that can monitor human memory performance by recognizing and characterizing high-gamma (65-250 Hz) and beta (14-30 Hz) band oscillations in the left Brodmann Area 40 (BA40) of the brain that correspond with the strength of memory encoding or correct recall. The signal processing method detects high-gamma and beta band oscillations in the electrical signals recorded from left BA40, and quantifies the spectral content, power, duration, onset, and offset of the oscillations. The oscillation's properties are used to classify the subject's memory performance on the basis of a comparison with the subject's prior human memory performance and the properties of the corresponding oscillations. A report of the subject's current memory performance can be utilized in a closed loop brain stimulation device that serves the purpose of enhancing human memory performance. |
| FILED | Wednesday, November 15, 2023 |
| APPL NO | 18/510470 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/374 (20210101) Original (OR) Class A61B 5/384 (20210101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36025 (20130101) A61N 1/36171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240090825 | Erdemir et al. |
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| APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
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| INVENTOR(S) | Ahmet Erdemir (Chagrin Falls, Ohio); Neda Abdollahi Nohouji (Austin, Texas); Benjamin Landis (Fort Worth, Texas) |
| ABSTRACT | A method of imaging and analyzing the joint of a patient, such as a knee, involves acquiring a three-dimensional data of the joint of the patient, reconstructing an articular contact geometry of the joint based on the 3D data, determining a tissue quality on articular contact geometry based on the 3D data, determining movement capacity of the joint based on the reconstructed articular contact geometry; and determining a motion signature of the joint based on the reconstructed articular contact geometry and the tissue quality. |
| FILED | Wednesday, July 26, 2023 |
| APPL NO | 18/226698 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/1121 (20130101) A61B 5/4514 (20130101) Original (OR) Class A61B 5/4528 (20130101) A61B 5/4851 (20130101) A61B 6/505 (20130101) A61B 6/5217 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240090871 | Dixon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rivanna Medical, Inc. (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam Dixon (Charlottesville, Virginia); Zachary Leonard (Charlottesville, Virginia); Paul Sheeran (Charlottesville, Virginia); Frank William Mauldin, JR. (Troy, Virginia) |
| ABSTRACT | An ultrasound transmission material that may be used to convey ultrasonic energy in medical ultrasound or non-destructive testing (NDT) applications. |
| FILED | Thursday, September 21, 2023 |
| APPL NO | 18/371027 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/4281 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240090875 | Fatemi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mostafa Fatemi (Rochester, Minnesota); Azra Alizad (Rochester, Minnesota); David P. Rosen (Rochester, Minnesota) |
| ABSTRACT | Systems and methods for determining viscoelasticity of curved tissue walls using ultrasound bladder vibrometry (UBV) to determine detrusor overactivity are provided. The UBV is a non-invasive technique utilizing, in a specific case, a focused ultrasound radiation force to excite Lamb waves in a curved bladder wall and pulse-echo techniques to track the tissue deformation propagating through such curved wall. |
| FILED | Monday, January 17, 2022 |
| APPL NO | 18/261622 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/485 (20130101) Original (OR) Class A61B 8/0858 (20130101) A61B 8/5223 (20130101) A61B 2576/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091155 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Qiyong Peter Liu (Newton, Massachusetts); William J. Merritt (Danvers, Massachusetts); Jihae Sohn (Salem, Massachusetts) |
| ABSTRACT | A method of treating plasma with a pretreatment solution that has a physiologically compatible spray dry stable acidic substance (SDSAS) and an amino acid, prior to or contemporaneously with spray drying of the plasma that results in greater recovery and greater long-term stabilization of the dried plasma proteins as compared to spray dried plasma that has not be subject to the formulation method of the present invention, as well as compositions related to plasma dried by the methods of the present invention. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/945126 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1682 (20130101) Original (OR) Class A61K 35/16 (20130101) Separation B01D 1/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091156 | Andrews et al. |
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| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Robert R. Andrews (Norfolk, Massachusetts); Herman E. Snyder (W. Lafayette, Indiana); William J. Merritt (Danvers, Massachusetts); Kyle D. Erickson (Melrose, Massachusetts); Evan P. Ordway (Salem, Massachusetts); Clair Strohl (Emmaus, Pennsylvania); Russell Barron (Boston, Massachusetts) |
| ABSTRACT | The present invention relates to spray drying plasma methodology that includes pretreating a donated liquid plasma unit, drying the liquid plasma using a spray drying apparatus with the spray drying disposable device that results in a disposable having the dried plasma, finishing the disposable using the finishing apparatus that is designed to seal and separate the disposable, and transform the disposable into a dried plasma unit. The methods of the present invention include storing the dried plasma unit and, when ready for use, reconstituting the dried plasma unit with reconstitution solution to obtain a plasma unit ready for transfusion into a recipient. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/945132 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1682 (20130101) Original (OR) Class A61K 35/16 (20130101) Separation B01D 1/18 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091164 | Scott et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan Alexander Scott (Evanston, Illinois); Bruce Scott Bochner (Evanston, Illinois); Clayton Hunter Rische (Evanston, Illinois) |
| ABSTRACT | The present disclosure provides methods of adsorbing proteins to the surface of a nanoparticle. Particularly, methods for adsorbing anti-Siglec-6 and anti-FcεRI antibodies to PPSU nanoparticles, are described. The disclosure further provides compositions comprising the nanoparticles are methods of their use to prevent mast cell secretion and anaphylaxis. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/464127 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5169 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/08 (20180101) Peptides C07K 16/2803 (20130101) C07K 16/2851 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091169 | MURPHY et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (COLUMBIA, South Carolina) |
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| INVENTOR(S) | ELIZABETH A. MURPHY (COLUMBIA, South Carolina); LORNE HOFSETH (COLUMBIA, South Carolina) |
| ABSTRACT | In general, disclosed herein are methods of treating an inflammatory disease or disorder by administering to the subject in need thereof a polyacetylene compound. The polyacetylene compound may be administered at a dose of from about 1 mg/kg body weight to about 10 mg/kg body weight. |
| FILED | Thursday, August 24, 2023 |
| APPL NO | 18/455124 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/045 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091175 | Nystoriak et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | Matthew Nystoriak (Floyds Knobs, Indiana); Aruni Bhatnagar (Prospect, Kentucky) |
| ABSTRACT | In certain embodiments, the present invention provides a method of modulating myocardial blood flow (MBF) as compared to a control in a patient in need thereof, comprising administering an agent that interacts with a Kvβ protein. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/370633 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091205 | WROBEL et al. |
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| APPLICANT(S) | Biohaven Therapeutics Ltd. (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jay Edward WROBEL (Lawrenceville, New Jersey); Allen B. REITZ (Lansdale, Pennsylvania); Jeffery Claude PELLETIER (Lafayette Hill, Pennsylvania); Garry Robert SMITH (Royersford, Pennsylvania); Haiyan BIAN (Princeton, New Jersey) |
| ABSTRACT | Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process. |
| FILED | Saturday, July 29, 2023 |
| APPL NO | 18/361836 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/0056 (20130101) A61K 9/485 (20130101) A61K 9/1617 (20130101) A61K 9/2004 (20130101) A61K 9/2018 (20130101) A61K 9/2063 (20130101) A61K 31/428 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/5377 (20130101) A61K 38/05 (20130101) A61K 38/06 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 277/82 (20130101) C07D 417/12 (20130101) Peptides C07K 5/0806 (20130101) C07K 5/0808 (20130101) C07K 5/0812 (20130101) C07K 5/06026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091225 | Gradilone et al. |
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| APPLICANT(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (ROCHESTER, Minnesota) |
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| INVENTOR(S) | Sergio A. Gradilone (Rochester, Minnesota); Nicholas F. LaRusso (Rochester, Minnesota) |
| ABSTRACT | An HDAC6-specific inhibitor (i.e., a compound of Formula I or II) is shown to reduce the pathogenesis associated with polycystic disease. Administration of an HDAC6-specific inhibitor attenuated many of the symptoms characteristic of polycystic liver disease including cyst formation, cyst growth and cholangiocyte proliferation. Treatment with a HDAC6-specific inhibitor also increased the amount of bile duct acetylated tubulin and β-catenin phosphorylation and/or acetylation while reducing bile duct β-catenin synthesis. These results demonstrate that HDAC6 is overexpressed in cystic cholangiocytes and that its pharmacological inhibition reduces cholangiocyte proliferation and cyst growth. |
| FILED | Wednesday, April 26, 2023 |
| APPL NO | 18/307559 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091238 | ZON et al. |
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| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Leonard I. ZON (Wellesley, Massachusetts); Alison M. TAYLOR (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates generally to methods, compositions and kits for treatment of ribosomal disorders and ribosomopathy, e.g. Diamond Blackfan anemia (DBA). In some embodiments, the invention relates to methods for the use of calmodulin inhibitors and calcium channel blockers for treatment of ribosomal disorders and ribosomopathy, e.g. Diamond Blackfan anemia (DBA). |
| FILED | Friday, April 07, 2023 |
| APPL NO | 18/297285 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/54 (20130101) A61K 31/145 (20130101) A61K 31/495 (20130101) A61K 31/553 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/4418 (20130101) A61K 31/4965 (20130101) A61K 31/5415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091240 | Bauer et al. |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
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| INVENTOR(S) | Bjoern Bauer (Lexington, Kentucky); Anika Maria Sophie Hartz (Lexington, Kentucky) |
| ABSTRACT | Methods for treating blood-brain barrier dysfunction and methods for treating recurrent seizures in a subject involve inhibiting nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX), 5-lipoxygenase (5-LOX), and cyclooxygenase-2 (COX-2). |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/370558 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) A61K 31/381 (20130101) A61K 31/407 (20130101) A61K 31/635 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091258 | GEORGIOU et al. |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | George GEORGIOU (Austin, Texas); Everett STONE (Austin, Texas) |
| ABSTRACT | Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids. |
| FILED | Tuesday, December 13, 2022 |
| APPL NO | 18/065451 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 38/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Enzymes C12Y 307/01003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091259 | Wu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Catherine J. Wu (Brookline, Massachusetts); Giacomo Oliveira (Boston, Massachusetts) |
| ABSTRACT | Disclosed are methods for identifying expanded, exhausted, and tumor-specific T-cell clonotypes for adoptive cell transfer, and methods of cancer treatment and modified T cells with anti-tumor T cell receptors (TCRs). |
| FILED | Friday, July 21, 2023 |
| APPL NO | 18/224865 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091264 | Kochenderfer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); TeneoBio, Inc. (Thousand Oaks, California) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); TeneoBio, Inc. (Thousand Oaks, California) |
| INVENTOR(S) | James N. Kochenderfer (Bethesda, Maryland); Norris Lam (Silver Spring, Maryland); Nathan Trinklein (Thousand Oaks, California); Katherine E. Harris (Thousand Oaks, California); Shelley Force Aldred (Thousand Oaks, California); Wim Van Schooten (Thousand Oaks, California) |
| ABSTRACT | Provided are chimeric antigen receptors (CARs) having antigen specificity for B-cell Maturation Antigen (BCMA). Also provided are related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the CARs. Methods of treating or preventing cancer in a mammal are also provided. |
| FILED | Thursday, November 30, 2023 |
| APPL NO | 18/524799 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 2317/21 (20130101) C07K 2317/73 (20130101) C07K 2317/569 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091265 | Dudakov et al. |
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| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Center (Seattle, Washington); Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Center (Seattle, Washington); Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Jarrod Dudakov (Seattle, Washington); Marcel van den Brink (New York, New York); Enrico Velardi (New York, New York); Hans-Peter Kiem (Seattle, Washington); Stefan Radtke (Seattle, Washington); Scott James (New York, New York) |
| ABSTRACT | The use of luteinizing hormone receptor (LHR) binding agents and luteinizing hormone (LH) agonists to enrich for primitive hematopoietic stem cell (pHSC) populations, to target pHSC for ablation, and/or to expand pHSC populations are described. The methods can be used to prepare therapeutic hematopoietic stem cell (HSC) populations, to prepare patients for therapeutic HSC transplants, and/or to treat malignancies, such as those associated with hyperproliferative HSC. |
| FILED | Monday, June 12, 2023 |
| APPL NO | 18/208490 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/28 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091279 | Mangalam et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of lowa Research Foundation (Iowa City, Iowa); The United States Government, as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ashutosh Mangalam (Iowa City, Iowa); Shailesh K. Shahi (Iowa City, Iowa); Sudeep Ghimire (Iowa City, Iowa); Samantha Jensen (New York, New York) |
| ABSTRACT | A method to prevent, inhibit or treat an inflammatory disease in a mammal, is provided that includes administering to a mammal in need thereof an effective amount of one or more isolated gut microbes and one or more phytoestrogens. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/464152 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) A61K 35/741 (20130101) Original (OR) Class A61K 2035/115 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091300 | CHEN et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Gong CHEN (Guangzhou, China PRC); Gang-Yi WU (State College, Pennsylvania); Lei ZHANG (State College, Pennsylvania); Jiu-Chao YIN (State College, Pennsylvania); Hana YEH (State College, Pennsylvania); Ning-Xin MA (State College, Pennsylvania); Grace LEE (State College, Pennsylvania) |
| ABSTRACT | Provided are methods and compositions from reprogramming human glial cells into human neurons. The reprogramming is achieved using combinations of compounds that can modify signaling via Transforming growth factor beta (TGF-β), Bone morphogenetic protein (BMP), glycogen synthase kinase 3 (GSK-3), and γ-secretase/Notch pathways. The reprogramming is demonstrated using groups of three or four compounds that are chosen from the group thiazovivin, LDN193189, SB431542, TTNPB, CHIR99021, DAPT, VPA, SAG, purmorphamine. Reprogramming is demonstrated using the group of LDN193189/CHIR99021/DAPT, the group of B431542/CHIR99021/DAPT, the group of LDN193189/DAPT/SB431542, the group of LDN193189/CHIR99021/SB431542, a three drug combination of SB431542/CHIR99021/DAPT. Reprogramming using functional analogs of the compounds is also provided, as are pharmaceutical formulations that contain the drug combinations. |
| FILED | Friday, November 10, 2023 |
| APPL NO | 18/506582 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4439 (20130101) A61K 38/05 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 2501/15 (20130101) C12N 2501/155 (20130101) C12N 2501/727 (20130101) C12N 2501/998 (20130101) C12N 2501/999 (20130101) C12N 2506/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091316 | GRINSPOON |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Steven K. GRINSPOON (Weston, Massachusetts) |
| ABSTRACT | The present application relates to novel methods for preventing, slowing the progression of, or treating nonalcoholic fatty liver (NAFL), nonalcoholic steatohepatitis (NASH), and/or liver fibrosis, and/or reducing the risks of liver cancer in subjects, such as HIV-infected subjects, using a GHRH molecule, e.g., trans-3-hexenoyl-GHRH(1-44)-NH2, or a pharmaceutically acceptable salt thereof. The subjects may have particular pathological features such as liver fibrosis, a hepatic fat fraction (HFF) of at least about 10%, serum alanine aminotransferase (ALT) levels of at least about 30 U/L, and/or a NAFLD Activity Score (NAS) of at least 4 or 5. |
| FILED | Wednesday, July 12, 2023 |
| APPL NO | 18/351169 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/25 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091319 | PERLMAN |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| INVENTOR(S) | Carrie E. PERLMAN (New York, New York) |
| ABSTRACT | A method of treating a patient having edematous lungs includes: administering a first surface tension-lowering component to the patient via the airways and administering a second surface tension-lowering component to the patient via the vasculature. The combined and complementary treatments may lower or normalize alveolar surface tension with improved efficiency and on a faster timescale, thereby reducing patient injury and mortality (FIG. 1). |
| FILED | Tuesday, January 18, 2022 |
| APPL NO | 18/272549 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/38 (20130101) Original (OR) Class A61K 38/395 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091326 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Lu Chen (Berkeley, California); Lingling Zhang (Berkeley, California) |
| ABSTRACT | Ocular serpinA3 activity is modulated to treat glaucoma by neuroprotection, comprising administering to an eye in need thereof a serpinA3 polypeptide or a nucleic acid encoding the serpinA3 polypeptide. |
| FILED | Saturday, November 25, 2023 |
| APPL NO | 18/518981 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/55 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091328 | LOVELL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan LOVELL (Niagara Falls, Canada); Xuedan HE (Amherst, New York); Shiqi ZHOU (Amherst, New York) |
| ABSTRACT | The present disclosure provides compositions and methods for generating immune response or enhancing immune response. The method comprises administering to a subject in need of treatment a compositions comprising liposomes comprising porphyrins with cobalt chelated thereto such that the cobalt metal resides within the bilayer in the porphyrin macrocycle, and polyhistidine tagged MHC-I restricted tumor peptides. |
| FILED | Tuesday, January 11, 2022 |
| APPL NO | 18/261456 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 39/001102 (20180801) Original (OR) Class A61K 2039/55555 (20130101) A61K 2039/55572 (20130101) A61K 2039/55577 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091329 | Eaton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | John W Eaton (Prospect, Kentucky); Kavitha Yaddanapudi (Louisville, Kentucky); Chi Li (Louisville, Kentucky) |
| ABSTRACT | Provided are compositions, optionally pharmaceutical compositions, that include a plurality of exosomes generated from stem cells, optionally ESCs and/or iPSCs, that have been modified to express a granulocyte-macrophage colony stimulating factor (GM-CSF) polypeptide, optionally a human GM-CSF polypeptide. Also provided are methods for employing the presently disclosed compositions for preventing and/or inhibiting tumor growth in subjects in need thereof, for preventing and/or inhibiting metastases in subject in need thereof, for inducing anti-tumor immune responses in subjects, and uses of the presently disclosed compositions for prevention and/or treatment of tumors and/or cancers and for the preparation of medicaments for treatment of tumors and/or cancers. |
| FILED | Monday, June 12, 2023 |
| APPL NO | 18/333400 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/545 (20130101) A61K 39/001139 (20180801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/535 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0696 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091364 | YU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hua YU (Glendora, California); Chunyan ZHANG (Glendora, California) |
| ABSTRACT | Provided herein are, inter ilia, methods and compositions for the treatment of cancer. The methods include administering a combination of an anti-STAT3-Toll-like receptor 9 (TLR9)-binding conjugate and a checkpoint inhibitor. The anti-STAT3-Toll-like receptor 9 (TLR9)-binding conjugate provide herein may be a CpG moiety bound to an anti-STAT3 siRNA through a covalent linker and the checkpoint inhibitor may be an anti-CTLA4 antibody. Administration of a combined effective amount of the anti-STAT3-Toll-like receptor 9 (TLR9)-binding conjugate and the checkpoint inhibitor results in surprisingly increased anti-tumor efficacy and CDS T cell activity. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/767398 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 47/549 (20170801) Original (OR) Class A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091378 | Schaffer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David V. Schaffer (Danville, California); Leah C. Byrne (San Francisco, California); Timothy P. Day (Berkeley, California); John G. Flannery (Berkeley, California) |
| ABSTRACT | The present disclosure provides recombinant adeno-associated virus (AAV) virions with altered capsid protein, where the recombinant AAV (rAAV) virions exhibit greater ability to cross barriers between intravitreal fluid and retinal cells, and thus greater infectivity of a retinal cell compared to wild-type AAV, and where the rAAV virions comprise a heterologous nucleic acid. The present disclosure provides methods of delivering a gene product to a retinal cell in an individual. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/167598 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0041 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 15/1082 (20130101) C12N 2310/20 (20170501) C12N 2750/14122 (20130101) C12N 2750/14142 (20130101) C12N 2750/14145 (20130101) C12N 2750/14171 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091384 | Milanova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Denitsa M. Milanova (Boston, Massachusetts); George M. Church (Brookline, Massachusetts); Noah Davidsohn (Brookline, Massachusetts); Carl Schoellhammer (Medford, Massachusetts); Robert S. Langer (Newton, Massachusetts); Anna I. Mandinova (Newton, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts) |
| ABSTRACT | A method for the systemic delivery of a polypeptide within a subject is provided by creating genetically modified skin cells via topical introduction of a genetically engineered virus which delivers a nucleic acid encoding a therapeutic polypeptide for expression by the skin cells, wherein the expressed therapeutic polypeptide is secreted by the skin cells and is introduced into the circulatory system of the subject. |
| FILED | Tuesday, May 30, 2023 |
| APPL NO | 18/325332 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/7023 (20130101) A61K 47/6901 (20170801) A61K 48/0075 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091441 | Steil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children`s Medical Center Corporation (Boston, Massachusetts); Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Garry Steil (Boston, Massachusetts); Howard Wolpert (Brookline, Massachusetts); Michael Agus (Newton, Massachusetts); Paulina Ortiz-Rubio (Brookline, Massachusetts) |
| ABSTRACT | This disclosure relates to systems and methods for diabetes management. |
| FILED | Thursday, July 27, 2023 |
| APPL NO | 18/227215 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1118 (20130101) A61B 5/4839 (20130101) A61B 5/7275 (20130101) A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/1723 (20130101) Original (OR) Class A61M 2205/502 (20130101) A61M 2230/201 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091664 | Andrews et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Robert R. Andrews (Norfolk, Massachusetts); Herman E. Snyder (W. Lafayette, Indiana); William J. Merritt (Danvers, Massachusetts); Kyle D. Erickson (Melrose, Massachusetts); Evan P. Ordway (Salem, Massachusetts); Clair Strohl (Emmaus, Pennsylvania); Russell Barron (Boston, Massachusetts) |
| ABSTRACT | The present invention includes an ease-of-use system that allows the spray drying disposable device to fit (e.g., align) in both spray drying apparatus and the spray drying finishing apparatus to safely operate the system. The system includes locating arrangements between the spray drying disposable and the spray drying apparatus and/or spray drying finishing apparatus, a first retainer and second retainer, a shorter disposable device that allows for effective spray drying of plasma, a feedback indicators of correct installment, redundant indicators of correct installment, easily accessible operator controls and emergency shut offs. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/945129 |
| CURRENT CPC | Separation B01D 1/18 (20130101) Original (OR) Class Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091665 | Andrews et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Robert R. Andrews (Norfolk, Massachusetts); Herman E. Snyder (W. Lafayette, Indiana); Kyle D. Erickson (Melrose, Massachusetts); William J. Merritt (Danvers, Massachusetts); Clair Strohl (Emmaus, Pennsylvania); Evan P. Ordway (Salem, Massachusetts); Russell Barron (Boston, Massachusetts) |
| ABSTRACT | An alignment system that allows a spray drying disposable to align in both spray drying apparatus and finishing apparatus. The first instance is a locating arrangement wherein a locator is disposed on the spray drying apparatus and/or finishing apparatus and another locator is on the spray drying head of the disposable such that the locators allow for alignment of the disposable with the spray drying apparatus or finishing apparatus. A second instance of an alignment element includes a guide that is offset as positioned on the spray drying head of the disposable. Yet a third instance of the alignment arrangement relates to the gas exhaust port. In a fourth instance, the alignment system includes a positioning arrangement to reversibly attach the outer wall of the disposable to the finishing apparatus. In a fifth and sixth instance, a retaining device that retains the spray drying head in the spray drying apparatus and/or finishing apparatus. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/945130 |
| CURRENT CPC | Separation B01D 1/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091666 | Meehan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Richard Meehan (Caragh Co, Ireland); Robert R. Andrews (Norfolk, Massachusetts); Herman E. Snyder (W. Lafayette, Indiana); William J. Merritt (Danvers, Massachusetts); Evan P. Ordway (Salem, Massachusetts); Clair Strohl (Emmaus, Pennsylvania); Qiyong Peter Liu (Newton, Massachusetts); Jihae Sohn (Salem, Massachusetts) |
| ABSTRACT | The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A). |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/097958 |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/00 (20130101) A61J 3/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 35/16 (20130101) Separation B01D 1/18 (20130101) Original (OR) Class B01D 1/0082 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091667 | Buckley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Lisa A. Buckley (Portland, Oregon); Mark A. Popovsky (Sharon, Massachusetts); Jihae Sohn (Salem, Massachusetts); Qiyong Peter Liu (Newton, Massachusetts); William J. Merritt (Danvers, Massachusetts) |
| ABSTRACT | A method of treating plasma with a pretreatment solution that has a physiologically compatible spray dry stable acidic substance (SDSAS) and an amino acid, prior to or contemporaneously with spray drying of the plasma that results in greater recovery and greater long-term stabilization of the dried plasma proteins as compared to spray dried plasma that has not be subject to the formulation method of the present invention, as well as compositions related to plasma dried by the methods of the present invention. |
| FILED | Thursday, September 14, 2023 |
| APPL NO | 18/467074 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0242 (20130101) Separation B01D 1/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091741 | Kunkel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | George Mason University (Fairfax, Virginia); Food and Drug Administration (Silver Spring, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alessandra Luchini Kunkel (Burke, Virginia); Silvia Isabel Cachaco (Manassas, Virginia); Rocío Solange Prisby (Vienna, Virginia); Amanda Haymond Still (Manassas, Virginia); Lance Liotta (Bethesda, Maryland); Luisa Gregori (Bethesda, Maryland); Cyrus Bett (Damascus, Maryland) |
| ABSTRACT | The present disclosure relates to compositions, devices and methods for removing/filtering out microorganisms from a given fluid. The composition of the present invention comprises a non-water imbibing, biocompatible filament and at least one affinity ligand that is capable of capturing the microorganism(s). The invention also discloses methods for detection, diagnosis, and/or treatment. |
| FILED | Tuesday, July 18, 2023 |
| APPL NO | 18/354345 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/26 (20130101) A61L 15/56 (20130101) Separation B01D 15/3804 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/265 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091762 | Schulte et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samuel J. Schulte (Pasadena, California); Jining Huang (Pasadena, California); Nikhil T. Linaval (Pasadena, California); Niles A. Pierce (South Pasadena, California) |
| ABSTRACT | The present disclosure relates to an HCR lateral flow device for amplified detection of a target in a sample and methods of using the same. In some embodiments, the device and methods of use combine the sensitivity of HCR signal amplification with the simplicity of the lateral flow assay format to facilitate user-friendly amplified detection of a target in a sample. |
| FILED | Wednesday, September 13, 2023 |
| APPL NO | 18/466726 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) Original (OR) Class B01L 2300/069 (20130101) B01L 2300/0825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092736 | Kohane et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Daniel S. Kohane (Newton, Massachusetts); Yueqin Zheng (Boston, Massachusetts) |
| ABSTRACT | Provided herein are compounds that are local anesthetics and useful for inducing selective sensory nerve blockade. Also provided are pharmaceutical compositions and kits comprising the compounds, and methods of inducing selective sensory nerve blockade by administering the compounds and/or compositions to a subject. |
| FILED | Thursday, October 29, 2020 |
| APPL NO | 17/773171 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 23/02 (20180101) Acyclic or Carbocyclic Compounds C07C 237/08 (20130101) C07C 237/10 (20130101) C07C 237/12 (20130101) Heterocyclic Compounds C07D 211/60 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092738 | Horenstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole Alana Horenstein (High Springs, Florida); Roger Lee Papke (Gainesville, Florida); Hina Andleeb (Boston, Massachusetts) |
| ABSTRACT | Provided are embodiments of para-substituted 1,1-dialkyl-4-phenylpiperazin-1-ium iodides advantageous for modulating inflammation that have been synthesized and their electrophysiology activities for α9, α9α10, and α7 nAChRs compared. The para position contained alkyl or aryl amides, or heterocyclic isosteres for the amide, and the alkyl groups were varied at the ammonium piperazine nitrogen to see if compensatory changes in size at this position of the molecule impacted function. The compounds were characterized with two-electrode voltage-clamp measurements on Xenopus oocytes expressing nAChRs. General, the compounds were more potent for α9-containing receptors than for α7, and the majority were either full or strong partial agonists for α9-containing nAChR. |
| FILED | Thursday, November 30, 2023 |
| APPL NO | 18/524322 |
| CURRENT CPC | Heterocyclic Compounds C07D 213/56 (20130101) Original (OR) Class C07D 263/32 (20130101) C07D 295/116 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092740 | WENTLAND |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Mark P. WENTLAND (Carlsbad, California) |
| ABSTRACT | 4-Hydroxybenzomorphans containing carboxamide or thiocarboxamide at the 3-position are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications. |
| FILED | Monday, April 17, 2023 |
| APPL NO | 18/301336 |
| CURRENT CPC | Heterocyclic Compounds C07D 221/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092746 | MEDINA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Epiodyne, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julio Cesar MEDINA (South San Francisco, California); Alok NERURKAR (San Diego, California); Corinne SADLOWSKI (London, United Kingdom); Frederick SEIDL (San Mateo, California); Heng CHENG (Fremont, California); Jason DUQUETTE (Millbrae, California); John LEE (Pacifica, California); Martin HOLAN (Stamford, Connecticut); Pingyu DING (Foster City, California); Xiaodong WANG (South San Francisco, California); Tien WIDJAJA (Lafayette, Colorado); Thomas NGUYEN (Newbury Park, California); Ulhas BHATT (Fremont, California); Yihong LI (South San Francisco, California); Zhi-liang WEI (Foster City, California) |
| ABSTRACT | Provided herein are opioid receptor modulators and pharmaceutical compositions comprising said compounds. |
| FILED | Monday, February 13, 2023 |
| APPL NO | 18/168155 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/65 (20130101) Heterocyclic Compounds C07D 213/56 (20130101) C07D 239/26 (20130101) C07D 263/58 (20130101) C07D 277/30 (20130101) Original (OR) Class C07D 295/155 (20130101) C07D 307/54 (20130101) C07D 333/24 (20130101) C07D 401/12 (20130101) C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092759 | Jorgensen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William L. Jorgensen (Deep River, Connecticut) |
| ABSTRACT | Provided herein are compounds of formula (I) or (I-A), which act as non-covalent inhibitors of SARS-CoV2 main protease (Mpro). The compounds of formula (I) or (I-A) are useful in treating COVID-19 infections, as well as reducing or ameliorating symptoms associated with COVID-19 infection. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 18/260744 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/10 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 409/14 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092807 | KUTTNER |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Venatorx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julian Rudolf KUTTNER (Einhausen, Hessen, Germany) |
| ABSTRACT | Described herein are boron-containing compounds, compositions, and methods for their preparation. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 18/248176 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092831 | Chanan-Khan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Asher Alban Akmal Chanan-Khan (Jacksonville, Florida); Aneel Paulus (Ocala, Florida); Thomas R. Caulfield (Jacksonville, Florida) |
| ABSTRACT | In some embodiments, the present disclosure provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt thereof. In some embodiments, the present disclosure provides a compound of Formula (II) as described herein, or a pharmaceutically acceptable salt thereof. Pharmaceutical compositions comprising the compound of Formula (I) or Formula (II), and methods of treating cancer using the compound of Formula (I) or Formula (II) are also provided. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/768199 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 5/1016 (20130101) Original (OR) Class C07K 5/06043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092835 | Birnbaum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Deutsches Rheuma-Forschungszentrum Berlin, ein Leibniz-Institut (Berlin, Germany); Charité - Universitätsmedizin Berlin (Berlin, Germany) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Deutsches Rheuma-Forschungszentrum Berlin, ein Leibniz-Institut (Berlin, Germany); Charité - Universitätsmedizin Berlin (Berlin, Germany) |
| INVENTOR(S) | Michael Birnbaum (Arlington, Massachusetts); Brooke Huisman (Clarkston, Michigan); Chiara Romagnani (Berlin, Germany); Timo Rückert (Berlin, Germany) |
| ABSTRACT | Peptides capable of binding to HLA-E and affecting immune cell activity are provided. Such peptides can selectively activate NKG2C+ immune cells such as natural killer (NK) cells and/or can inhibit NKG2A+ cells to decrease or suppress immune cell responses. Methods of use of the peptides are also disclosed, for instance, for treating or inhibiting the development or progression of a multitude of illnesses and conditions, including autoimmune disease, infectious disease such as viral or bacterial infection, and proliferative disorders such as cancer. |
| FILED | Wednesday, June 07, 2023 |
| APPL NO | 18/331004 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Peptides C07K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092841 | Matoba |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nobuyuki Matoba (Owensboro, Kentucky) |
| ABSTRACT | The treatment of growth factor receptor-mediated cancers, such as epidermal growth factor receptor- (EGFR-) and/or insulin-like growth factor 1 receptor- (IGF1R-) mediated cancers, e.g., lung cancer such as non-small cell lung cancer, which is sensitive to polypeptides specifically binds a high-mannose-type glycan epitope, is described. Methods for reducing activation of EGFR and/or IGF1R in cancer cells, inhibiting cancer cell migration, treatment of cancer and/or reduction of tumor growth in subjects (e.g., human patients) are provided. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 18/261950 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092844 | NOYES et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York); The Governing Council of the University of Toronto (Toronto, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marcus NOYES (Monmouth Junction, New Jersey); Mikko TAIPALE (Toronto, Canada); Philip M. KIM (Toronto, Canada) |
| ABSTRACT | Provided are modified proteins comprising an introduced zinc finger DNA binding domain, and polynucleotides encoding the modified proteins. The modified proteins have a changed DNA binding location relative a DNA binding location of the protein in its unmodified form. The modified proteins include, in addition to the introduced zinc finger DNA binding domain, a gene expression activator domain or a gene expression repressor domain. Methods of using the modified proteins to activate or repress gene expression are also provided. The methods include prophylactic and therapeutic approaches. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 18/264207 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4702 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092845 | BRISCOE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHIDLREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | David M. BRISCOE (Sharon, Massachusetts); Diane BIELENBERG (Andover, Massachusetts); Johannes WEDEL (Jamaica Plain, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions comprising or using mutant semaphorin polypeptides. |
| FILED | Friday, March 10, 2023 |
| APPL NO | 18/119920 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Peptides C07K 14/4703 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092846 | Camarero Palao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julio Camarero Palao (Los Angeles, California); Paul Beringer (Los Angeles, California); Mansour Dughbaj (Los Angeles, California); Rajasekaran Ganesan (Los Angeles, California) |
| ABSTRACT | Disclosed herein are novel engineered cyclotides with effective broad-spectrum antibacterial activity against several ESKAPE bacterial strains and clinical isolates. |
| FILED | Tuesday, June 20, 2023 |
| APPL NO | 18/212068 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 14/4703 (20130101) Original (OR) Class C07K 2317/73 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092854 | Krupnick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Sasha Krupnick (St. Louis, Missouri); Eric Reed Lazear (St. Louis, Missouri); Daved Henry Fremont (St. Louis, Missouri) |
| ABSTRACT | The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to a ligand and may improve immunotherapy by limiting side effects associated with immunotherapy. |
| FILED | Monday, June 12, 2023 |
| APPL NO | 18/333172 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/65 (20170801) A61K 47/642 (20170801) Peptides C07K 14/005 (20130101) C07K 14/55 (20130101) Original (OR) Class C07K 2299/00 (20130101) C07K 2319/20 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/24122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092857 | Bernstein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| INVENTOR(S) | Irwin D. Bernstein (Seattle, Washington); Suzanne Furuyama (Mountlake Terrace, Washington); Kristen Johnson (Seattle, Washington) |
| ABSTRACT | Delta-like non-canonical Notch ligand 1 (DLK1) inhibitors are disclosed. The DLK1 inhibitors can be used to treat cancers such as myelodysplastic syndrome (MDS), and cancers of the liver, breast, brain, pancreas, colon, lung, kidney, ovary, testes, and/or adrenal gland, among other uses described herein. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/456339 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0694 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092862 | Campana et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dario Campana (Singapore, Singapore); Chihaya Imai (Niigata City, Japan) |
| ABSTRACT | The present invention relates to a chimeric receptor capable of signaling both a primary and a co-stimulatory pathway, thus allowing activation of the co-stimulatory pathway without binding to the natural ligand. The cytoplasmic domain of the receptor contains a portion of the 4-1BB signaling domain. Embodiments of the invention relate to polynucleotides that encode the receptor, vectors and host cells encoding a chimeric receptor, particularly including T cells and natural killer (NK) cells and methods of use. |
| FILED | Wednesday, May 03, 2023 |
| APPL NO | 18/311318 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) Peptides C07K 14/47 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) Original (OR) Class C07K 16/2866 (20130101) C07K 16/2878 (20130101) C07K 16/2896 (20130101) C07K 2319/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) C12N 2501/23 (20130101) C12N 2502/11 (20130101) C12N 2502/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092867 | HUBBELL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois); Imperial College Innovations Limited (London, United Kingdom) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); Imperial College Innovations Limited (London, United Kingdom) |
| INVENTOR(S) | Jeffrey A. HUBBELL (Chicago, Illinois); Anna M. RANDI (London, United Kingdom); Jun ISHIHARA (London, United Kingdom); Ako ISHIHARA (London, United Kingdom); Priscilla BRIQUEZ (Chicago, Illinois); Richard STARKE (London, United Kingdom) |
| ABSTRACT | The methods and compositions described herein address the need in the art by providing peptides and polypeptides comprising a growth factor binding domain. In some embodiments, the peptides have an amino acid sequence that is at least 80% identical to one of SEQ ID NOS:1-7, 13-15, 49-50, or 66-70, or a fragment thereof; wherein the peptide is less than 300 amino acids in length. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/352101 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/7007 (20130101) A61K 38/00 (20130101) A61K 38/18 (20130101) A61K 38/39 (20130101) A61K 47/6435 (20170801) A61K 47/6903 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/22 (20130101) A61L 2300/412 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) Peptides C07K 14/78 (20130101) Original (OR) Class C07K 14/475 (20130101) C07K 14/8121 (20130101) C07K 14/70546 (20130101) C07K 16/18 (20130101) C07K 2317/55 (20130101) C07K 2319/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092886 | SHAFIKHANI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rush University Medical Center (Chicago, Illinois) |
| ASSIGNEE(S) | Rush University Medical Center (Chicago, Illinois) |
| INVENTOR(S) | Sasha H. SHAFIKHANI (Elmwood Park, Illinois); Ruchi ROY (Chicago, Illinois) |
| ABSTRACT | Methods of modulating IL-10 signaling in a diabetic patient are provided. The methods include administering a therapeutically effective amount of an agent that inhibits Interleukin-10 (IL-10) signaling to a wound site. The agent may antagonize IL-10 or IL-10R to inhibit IL-10 signaling. In some aspects the agent is an antibody or antigen-binding fragment that specifically binds to IL-10 or IL-10R. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/767620 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) Peptides C07K 16/244 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092895 | MORGENSTERN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Travis MORGENSTERN (New York, New York); Henry COLECRAFT (Robbinsville, New Jersey) |
| ABSTRACT | The present disclosure provides, inter alia, chimeric nanobody compositions that selectively modulate the function of a target protein within a defined population of cells. Also provided are methods for treating diseases such as ion channelopathies. |
| FILED | Monday, November 20, 2023 |
| APPL NO | 18/514836 |
| CURRENT CPC | Peptides C07K 16/28 (20130101) Original (OR) Class C07K 16/40 (20130101) C07K 2317/31 (20130101) C07K 2317/35 (20130101) C07K 2317/76 (20130101) C07K 2317/569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092900 | Majeti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ravindra Majeti (Palo Alto, California); Irving L. Weissman (Stanford, California) |
| ABSTRACT | Markers of acute myeloid leukemia stem cells (AMLSC) are identified. The markers are differentially expressed in comparison with normal counterpart cells, and are useful as diagnostic and therapeutic targets. |
| FILED | Tuesday, August 01, 2023 |
| APPL NO | 18/363584 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57426 (20130101) Original (OR) Class G01N 33/57492 (20130101) G01N 2333/4725 (20130101) G01N 2333/70596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092904 | Pan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Deng Pan (Boston, Massachusetts); Kai W. Wucherpfennig (Brookline, Massachusetts) |
| ABSTRACT | The present invention is based, in part, on the identification of novel biomarkers, and methods of modulate thereof, for sensitizing cancer cells to T cell-mediated killing. |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/234229 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 38/19 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2809 (20130101) Original (OR) Class C07K 16/2812 (20130101) C07K 16/2815 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092932 | Andreana et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Toledo (Toledo, Ohio) |
| ASSIGNEE(S) | The University Of Toledo (Toledo, Ohio) |
| INVENTOR(S) | Peter Andreana (Toledo, Ohio); Kevin Trabbic (Toledo, Ohio); Mengchao Shi (Toledo, Ohio); Jean Paul Bourgault (Toledo, Ohio) |
| ABSTRACT | Entirely carbohydrate immunogens, monoclonal antibodies generated from immune responses to entirely carbohydrate immunogens, vaccine compositions, pharmaceutical compositions, and methods of making and using the same, are described. |
| FILED | Friday, November 10, 2023 |
| APPL NO | 18/506571 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 39/001172 (20180801) A61K 39/001173 (20180801) A61K 39/39558 (20130101) A61K 47/61 (20170801) A61K 47/6855 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/30 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092935 | Cummings et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Richard D. Cummings (Brookline, Massachusetts); Elliot Chaikof (Newton, Massachusetts); Yasuyuki Matsumoto (Revere, Massachusetts); Matthew R. Kudelka (Decatur, Georgia) |
| ABSTRACT | The present disclosure provides anti-Tn antibodies (e.g., BaGs6 and/or Remab6) having superior specificity for Tn antigen on cancer cells. Also provided herein, are nucleic acids, vectors, or vector sets that encode the anti-Tn antibody. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/767766 |
| CURRENT CPC | Peptides C07K 16/2896 (20130101) C07K 16/3076 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/40 (20130101) C07K 2317/76 (20130101) C07K 2317/732 (20130101) C07K 2317/734 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092968 | Saltzman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | W. Mark Saltzman (New Haven, Connecticut); Yuhang Jiang (New Haven, Connecticut) |
| ABSTRACT | Poly(amine-co-ester) polymers, methods of forming active agent-load polyplexes and particles therefrom, and methods of using them for delivery of nucleic acid agents with optimal uptake have been developed. Examples demonstrate critical molecular weights in combination with exposed carboxylic and/or hydroxyl groups, and methods of making. Typically, the compositions are less toxic, more efficient at drug delivery, or a combination thereof compared to a control other transfection reagents. In some embodiments, the compositions are suitable for in vivo delivery, and can be administered systemically to a subject to treat a disease or condition. |
| FILED | Friday, July 28, 2023 |
| APPL NO | 18/361630 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/595 (20170801) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/685 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093144 | Bao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Min Bao (Pasadena, California); Magdalena Zernicka-Goetz (Pasadena, California) |
| ABSTRACT | Disclosed herein include methods and compositions for use in generating synthetic embryos. In some embodiments, the method comprises culturing stem cells that over-express at least one Cadherin. |
| FILED | Friday, September 01, 2023 |
| APPL NO | 18/459669 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0604 (20130101) Original (OR) Class C12N 2501/603 (20130101) C12N 2502/99 (20130101) C12N 2506/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093154 | Sareen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Dhruv Sareen (Porter Ranch, California); Roberta de Souza Santos (Los Angeles, California) |
| ABSTRACT | Diabetes is a clinical condition that affects millions of people worldwide, and is treated by insulin replacement therapies. New strategies to create scalable and compatible pancreatic islets containing insulin-producing beta cells are necessary as an alternative to limited supply of cadaveric islets or multiple exogenous insulin applications. Improvements are still necessary since many immature polyhormonal cells remain, and cannot attain a monohormonal state. During human development, pancreas co-develops with endothelium and shares signals, allowing for better maturation of beta cells, and this is not included in the current differentiation protocols. The organchip microfluidic devices allows dynamic co-culture of different cells, thus resembling in vivo physiology. Here the Inventors establish organ-chip models co-culturing human iPSC-derived pancreatic precursors with iPSC-derived endothelial cells to obtain more functional and monohormonal iPSC-derived beta cells. |
| FILED | Monday, January 31, 2022 |
| APPL NO | 18/272969 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/39 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0676 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093156 | Tabin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Clifford J. Tabin (Cambridge, Massachusetts); Yuji Atsuta (Cambridge, Massachusetts); Alan R. Rodrigues (Cambridge, Massachusetts); ChangHee Lee (Cambridge, Massachusetts); Olivier Pourquie (Boston, Massachusetts) |
| ABSTRACT | The disclosure provides methods and compositions for reprogramming fibroblasts into limb progenitors. |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/450242 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0697 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2501/60 (20130101) C12N 2506/13 (20130101) C12N 2513/00 (20130101) C12N 2533/90 (20130101) C12N 2537/10 (20130101) C12N 2740/15043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093157 | Tuan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Rocky S. Tuan (Pittsburgh, Pennsylvania); Hang Lin (Pittsburgh, Pennsylvania); Thomas P. Lozito (Pittsburgh, Pennsylvania); Peter Alexander (Wexford, Pennsylvania); Douglas Allen Nelson, Jr. (Pittsburgh, Pennsylvania); Riccardo Gottardi (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are various bioreactor devices and systems for growing cellular material, and related methods of growing cellular material. In some cases, a system can include a well plate having a plurality of wells and a bioreactor situated in each well of the well plate. In some cases, a bioreactor can include an inner body which divides the bioreactor into several distinct chambers and facilitates the growth of a multi-tissue sample in the bioreactor. In some cases, a system can include a mechanical actuator situated to mechanically stress tissues grown in a bioreactor. |
| FILED | Wednesday, November 15, 2023 |
| APPL NO | 18/510350 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/12 (20130101) C12M 23/16 (20130101) C12M 23/34 (20130101) C12M 35/04 (20130101) C12M 35/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0697 (20130101) Original (OR) Class C12N 2502/1311 (20130101) C12N 2502/1317 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093160 | Steinmetz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California); Hema Masarapu (Cleveland, Ohio); He Hu (Cleveland, Ohio) |
| ABSTRACT | A method of targeting cancer tissue in a subject includes administering to the subject a plurality of functionalized Tymovirus virus or virus-like particles loaded with or conjugated to an imaging agent, a therapeutic agent or a targeting agent. |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/239463 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/136 (20130101) A61K 47/55 (20170801) A61K 47/546 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093184 | Fang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Linglan Fang (Stanford, California); Eric T. Kool (Stanford, California) |
| ABSTRACT | Compositions and methods are provided for the reversible modification of RNA to enhance RNA in-solution and enzymatic stability by reaction with acylimidazoles, sulfonyltriazoles, or sulfonylimidazoles. 2′-OH acylation protects RNA from hydrolytic and enzymatic degradation. Water-soluble organocatalysts can accelerate the reversal of acylation adducts and functionally restore RNAs, alternatively the acylation is spontaneously reversed in a cellular environment. Chemically tuned 2′-OH acylation can be spontaneously released in cells to restore RNA biological functions including translation. mRNA can be selectively modified at the 2′-OH of poly(A)-tail for enhanced in-cell stability and enhanced total protein output. |
| FILED | Thursday, October 05, 2023 |
| APPL NO | 18/377236 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 2310/321 (20130101) C12N 2310/344 (20130101) C12N 2320/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240093190 — ENGINEERED NUCLEIC ACIDS TARGETING LONG NONCODING RNA INVOLVED IN PATHOGENIC INFECTION
| US 20240093190 | Si et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Longlong Si (Cambridge, Massachusetts); Haiqing Bai (Cambridge, Massachusetts); Rachelle Pranti-Baun (Cambridge, Massachusetts); Donald E. Ingber (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides compositions and methods for inhibiting viral pathogenesis by targeting long noncoding ribonucleic acids. |
| FILED | Tuesday, January 18, 2022 |
| APPL NO | 18/272933 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/113 (20130101) C12N 2320/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093193 | ZHANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng ZHANG (Cambridge, Massachusetts); Silvana Konermann (Zurich, Switzerland); James Dahlman (Cambridge, Massachusetts); Omar Abudayyeh (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are stmctural information on the Cas protein of the CRISPR-Cas system, use of this information in generating modified components of the CRISPR complex, vectors and vector systems which encode one or more components or modified components of a CRISPR complex, as well as methods for the design and use of such vectors and components. Also provided are methods of directing CRISPR complex formulation in eukaryotic cells and methods for utilizing the CRISPR-Cas system. In particular the present invention comprehends optimized functional CRISPR-Cas enzyme systems. |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/449940 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2207/12 (20130101) A01K 2217/05 (20130101) A01K 2227/105 (20130101) A01K 2267/03 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Peptides C07K 2319/00 (20130101) C07K 2319/09 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/115 (20130101) C12N 15/635 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) C12N 2310/3519 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 2600/178 (20130101) Enzymes C12Y 301/21004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093203 | Garcia-Blanco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mariano A. Garcia-Blanco (Galveston, Texas); Gaddiel Galarza-Munoz (Galveston, Texas); Shelton S. Bradrick (Galveston, Texas) |
| ABSTRACT | The present invention includes compositions and methods for treating an autoimmune disorder or a cancer in a subject in need thereof, the method comprising: administering an effective amount of a composition comprising an oligonucleotide that specifically binds a complementary sequence of the Interleukin-7 receptor (IL7R) pre-mRNA that influences splicing of exon 6, wherein the SM-ASO increases or decreases inclusion of exon 6 in IL7R pre-mRNAs and respectively decreases or increases expression of the soluble isoform of IL7R (sIL7R). In certain embodiments, the oligonucleotide is an antisense oligonucleotide (ASO), or a splice-modulating antisense oligonucleotide (SM-ASO). |
| FILED | Monday, October 16, 2023 |
| APPL NO | 18/487429 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2320/31 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093204 | Garcia-Blanco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Mariano A. Garcia-Blanco (Galveston, Texas); Gaddiel Galarza-Munoz (Galveston, Texas); Shelton S. Bradrick (Galveston, Texas) |
| ABSTRACT | The present invention includes compositions and methods for treating an autoimmune disorder or a cancer in a subject in need thereof, the method comprising: administering an effective amount of a composition comprising an oligonucleotide that specifically binds a complementary sequence of the Interleukin-7 receptor (IL7R) pre-mRNA that influences splicing of exon 6, wherein the SM-ASO increases or decreases inclusion of exon 6 in IL7R pre-mRNAs and respectively decreases or increases expression of the soluble isoform of IL7R (sIL7R). In certain embodiments, the oligonucleotide is an antisense oligonucleotide (ASO), or a splice-modulating antisense oligonucleotide (SM-ASO). |
| FILED | Monday, November 06, 2023 |
| APPL NO | 18/503125 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2320/31 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093206 | Close et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | 490 BioTech, Inc. (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Close (Knoxville, Tennessee); Steven Ripp (Knoxville, Tennessee); Gary Sayler (Blaine, Tennessee) |
| ABSTRACT | A system for stable expression of gene pathways in cell lines, methods of making cell lines with stable expression of gene pathways, and methods of using the same are disclosed herein. The system comprises a nucleic acid construct configured to encode at least two genes of a multigene pathway in a cell. The nucleic acid construct comprises a plurality of nucleic acid sequences, wherein the plurality of nucleic acid sequences comprises: a first nucleic acid sequence encoding at least one gene of the multigene pathway; a first protease recognition nucleic acid sequence encoding a protease recognition site; a first linker nucleic acid sequence encoding a linker region, wherein the linker region comprises a viral 2A peptide; and a second nucleic acid sequence encoding at least one gene of the multigene pathway. |
| FILED | Tuesday, March 15, 2022 |
| APPL NO | 18/282320 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0686 (20130101) C12N 9/0008 (20130101) C12N 9/0071 (20130101) C12N 9/93 (20130101) C12N 9/1029 (20130101) C12N 15/52 (20130101) Original (OR) Class C12N 15/85 (20130101) Enzymes C12Y 102/0105 (20130101) C12Y 114/14003 (20130101) C12Y 203/01 (20130101) C12Y 602/01019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093208 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ting Lu (Savoy, Illinois); Wentao Kong (Champaign, Illinois) |
| ABSTRACT | Provided herein are systems that provide a genetic program to control bacterial life cycle and function execution, thereby conferring programmable microbial transition between planktonic and biofilm states and facilitating the development of cellular functions across physiological domains. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/463837 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/22 (20130101) C12N 9/0071 (20130101) C12N 9/2417 (20130101) C12N 9/2471 (20130101) C12N 15/11 (20130101) C12N 15/74 (20130101) C12N 15/635 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2509/00 (20130101) C12N 2800/80 (20130101) C12N 2800/101 (20130101) C12N 2830/002 (20130101) C12N 2830/005 (20130101) Enzymes C12Y 114/14 (20130101) C12Y 302/01001 (20130101) C12Y 302/01023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093226 | ZECHIEDRICH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas); TWISTER BIOTECH, LLC (Houston, Texas) |
| ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas); BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | E. Lynn ZECHIEDRICH (Houston, Texas); Jonathan Marcus FOGG (Houston, Texas); Lirio Milenka AREVALO-SOLIZ (Houston, Texas); Daniel James CATANESE (Houston, Texas); Christopher E. COKER (Houston, Texas) |
| ABSTRACT | MiniVectors and compositions containing MiniVectors that are ultrapure, and methods of making and using ultrapure MiniVectors for gene therapy uses, including long term repeated gene therapy uses. |
| FILED | Thursday, September 08, 2022 |
| APPL NO | 17/930652 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) Original (OR) Class C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093236 | Kaplan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (MEDFORD, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Dana Cairns (Somerville, Massachusetts) |
| ABSTRACT | The present invention provides an in vitro model of Alzheimer's disease (AD) comprising human induced neuronal stem cells (hiNSCs) infected with herpes simplex 1 that develop an Alzheimer's disease phenotype. The invention further provides AD model comprising genetically modified HSV infected hiNSCs. The use of these in vitro AD models for high throughput screening and phenotypic analysis are also provided. |
| FILED | Thursday, July 27, 2023 |
| APPL NO | 18/360217 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2513/00 (20130101) C12N 2710/16643 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093242 | Pavel-Dinu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Mara Pavel-Dinu (Stanford, California); Matthew H. Porteus (Stanford, California) |
| ABSTRACT | The present disclosure provides methods and compositions for treating SCID-X1 in subjects, comprising genetically modifying cells from the subjects ex vivo by integrating a full-length, codon-optimized IL2RG cDNA at the endogenous IL2RG locus. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 18/007439 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 9/22 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 15/1138 (20130101) C12N 2310/20 (20170501) C12N 2310/315 (20130101) C12N 2310/344 (20130101) C12N 2510/00 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093289 | Haase et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christa Haase (Somerville, Massachusetts); Dmitry Richter (Somerville, Massachusetts); Charles Lin (Arlington, Massachusetts) |
| ABSTRACT | A system and method for image-guided cell isolation from a region of interest of a subject is disclosed. The system and method include imaging the subject using optical microscopy to identify the region of interest in a target anatomy, inserting a micropipette into the region of interest under guidance of the optical microscopy, and aspirating at least one cell of a target population of cells in the region of interest under guidance of the optical microscopy. The method further includes analyzing the at least one cell aspirated from the region of interest. |
| FILED | Tuesday, August 01, 2023 |
| APPL NO | 18/363298 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/02 (20130101) A61B 18/20 (20130101) A61B 90/20 (20160201) A61B 2018/00565 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093291 | Delley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | CZ BIOHUB SF, LLC (San Francisco, California) |
| INVENTOR(S) | Cyrille L. Delley (Oakland, California); Adam Abate (Oakland, California) |
| ABSTRACT | The present disclosure provides materials and methods for sequencing a tissue sample and that allows spatial information about the tissue to be recovered by sequencing approaches at a single cell level. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 18/266085 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093294 | Xie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaoliang Sunney Xie (Lexington, Massachusetts); Katsuyuki Shiroguchi (Arlington, Massachusetts); Peter A. Sims (Cambridge, Massachusetts); Tony Z. Jia (Cambridge, Massachusetts) |
| ABSTRACT | Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided. |
| FILED | Tuesday, November 28, 2023 |
| APPL NO | 18/520654 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) C12N 2320/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6853 (20130101) C12Q 1/6874 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093303 | Lippman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); New York University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott M. Lippman (La Jolla, California); Webster K. Cavenee (La Jolla, California); Teresa Davoli (New York, New York) |
| ABSTRACT | The disclosure further provides diagnostic, prognostic and therapeutic methods, which are based, at least in part, on determination of the identity of a genotype of interest identified herein. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 18/264314 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093310 | Emery et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Caroline Emery (Kansas City, Missouri); Rajee Antony (Norwood, Massachusetts); Levi A. Garraway (Newton, Massachusetts) |
| ABSTRACT | Nucleic acids and proteins having a mutant C-RAF sequence, and methods of identifying patients having cancer who are likely to benefit from a combination therapy and methods of treatment are provided. |
| FILED | Monday, September 11, 2023 |
| APPL NO | 18/464360 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 207/11001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093746 | Allison et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Savior Brain Inc. (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Daniel Allison (Lake Oswego, Oregon); Christoph Eduard Mack (Seattle, Washington) |
| ABSTRACT | Impact protection for people and goods involved in athletics, transportation, industrial, and military activities comprises a hybrid crush zone shock absorber apparatus, systems, and methods of using the same. More specifically, the present invention reduces forces transmitted to a person or item exposed to impact. Primary applications are in protective articles such as helmets and body padding, surfaces which people or goods may impact, and shock isolation packaging. In addition to reduction in transmitted impact forces, our invention provides clear, irreversible visual indication of the state of readiness of the protective gear to which it is fitted. |
| FILED | Wednesday, July 12, 2023 |
| APPL NO | 18/220981 |
| CURRENT CPC | Hats; Head Coverings A42B 3/067 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 7/003 (20130101) Original (OR) Class F16F 2224/048 (20130101) F16F 2230/0023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094106 | MAO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leidong MAO (Watkinsville, Georgia); Yang LIU (Albany, California) |
| ABSTRACT | The present application provides devices, kits, and methods for label-free separation of cells and/or other small particles with high resolution and throughput. Devices, kits, and methods of the present disclosure include a focusing stage for inertial based focusing of cells/particles in a sample followed by ferrohydrodynamic, size-based separation in a separation stage. These devices, kits and methods provide the ability to separate and enrich target cells/particles from a sample with high resolution and efficiency. |
| FILED | Thursday, February 03, 2022 |
| APPL NO | 18/274507 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0272 (20130101) Original (OR) Class G01N 2015/016 (20240101) G01N 2015/0288 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094193 | Ben-Yakar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adela Ben-Yakar (Austin, Texas); Evan Hegarty (Austin, Texas); Sudip Mondal (Austin, Texas); Navid Ghorashian (Sunnyvale, California); Sertan Kutal Gökçe (Austin, Texas); Christopher Martin (Austin, Texas) |
| ABSTRACT | A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, maybe controlled via hydraulic pressure. |
| FILED | Monday, August 14, 2023 |
| APPL NO | 18/449351 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502723 (20130101) B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2200/0668 (20130101) B01L 2300/14 (20130101) B01L 2300/023 (20130101) B01L 2300/087 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/05 (20130101) G01N 21/6458 (20130101) G01N 33/502 (20130101) G01N 33/5085 (20130101) Original (OR) Class G01N 35/00029 (20130101) G01N 35/00871 (20130101) G01N 2021/6482 (20130101) G01N 2035/00148 (20130101) G01N 2201/12 (20130101) Image or Video Recognition or Understanding G06V 20/693 (20220101) G06V 20/695 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094208 | Garraway et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Levi A. Garraway (Newton, Massachusetts); Caroline Emery (Kansas City, Missouri); Nikhil Wagle (Brookline, Massachusetts) |
| ABSTRACT | An isolated nucleic acid molecule encoding a mutant MEK1 protein having MEK1 activity is disclosed. The mutant MEK1 protein comprises an amino acid substitution at position 121 of wild-type MEK1 shown in SEQ ID NO: 2. The amino acid substitution confers resistance to one or more RAF or MEK inhibitors on a cell expressing the mutant MEK1 protein. |
| FILED | Wednesday, September 06, 2023 |
| APPL NO | 18/461820 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/005 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1205 (20130101) C12N 15/1003 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6809 (20130101) C12Q 1/6827 (20130101) C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 207/12002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5743 (20130101) Original (OR) Class G01N 2333/91205 (20130101) G01N 2500/10 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094209 | Greene et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evan Greene (Seattle, Washington); Greg Finak (Lake Forest Park, Washington); Raphael Gottardo (Seattle, Washington) |
| ABSTRACT | Disclosed herein are to markers, methods and systems for identifying cell populations, diagnosing, monitoring and treating cancer, including biomarkers predictive of response to immunotherapy treatment in Merkel cell carcinoma. |
| FILED | Wednesday, November 15, 2023 |
| APPL NO | 18/509663 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5743 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 25/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094216 | FRIZZELL |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (COLUMBIA, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | NORMA FRIZZELL (COLUMBIA, South Carolina) |
| ABSTRACT | Methods disclosed herein are directed to treating a mitochondrial disorder in a subject. For instance, methods can be utilized to treat a mitochondrial disorder based on an amount of at least one metabolite measured in a biological sample of a subject. |
| FILED | Wednesday, August 30, 2023 |
| APPL NO | 18/458500 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/25 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6812 (20130101) Original (OR) Class G01N 33/6848 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094321 | Emir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Uzay Emir (West Lafayette, Indiana); Mark Chiew (West Lafayette, Indiana) |
| ABSTRACT | A method of performing magnetic resonance spectroscopic imaging (MRSI) includes transmitting a multi-slice excitation pulse through tissue, the multi-slice excitation pulse configured to generate multi-slice MRSI signals. The method also includes performing density weighted concentric ring acquisition on the multi-slice MRSI signals. The method further includes receiving the generated multi-slice MRSI signals in a plurality of sensors disposed in various locations around the tissue. Imaging data is reconstructed based on the acquired imaging signals. A representation of the data is displayed. |
| FILED | Tuesday, November 28, 2023 |
| APPL NO | 18/521825 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) G01R 33/4824 (20130101) G01R 33/4828 (20130101) G01R 33/4835 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094517 | CUNNINGHAM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian T. CUNNINGHAM (Champaign, Illinois); Nantao LI (Champaign, Illinois); Taylor D. CANADY (Champaign, Illinois); Qinglan HUANG (Santa Clara, California); Xing WANG (Champaign, Illinois) |
| ABSTRACT | Disclosed herein are methods and systems that use a photonic crystal (PC) for interference scattering microscopy. Incident light is directed onto a surface of the PC and couples into a photonic crystal guided resonance (PCGR) mode of the PC such that less than 1% of the incident light is transmitted through the PC as transmitted light. One or more particles adjacent to the surface of the PC scatter a portion of the light coupled into the PCGR mode as scattered light. An image comprising a pattern of constructive and destructive interference between the transmitted light and the scattered light is formed, and an image sensor may capture one or more image frames of the image Imaging processing of the one or more image frames can be used to identify at least one scattering center corresponding to at least one particle of the one or more particles. |
| FILED | Thursday, February 03, 2022 |
| APPL NO | 18/263749 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0056 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095381 | SADEH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Norman SADEH (Pittsburgh, Pennsylvania); Bin LIU (Pittsburgh, Pennsylvania); Anupam DAS (Pittsburgh, Pennsylvania); Martin DEGELING (Pittsburgh, Pennsylvania); Florian SCHAUB (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system comprises a IoT resource and a computing device of a user. The computing device comprises a processor that executes a personal privacy app that receives data about the IoT resource and communicates a preference setting for the user with respect to the IoT device. The preference setting is based on the data received about the IoT resource. |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/239267 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/604 (20130101) Original (OR) Class G06F 21/629 (20130101) G06F 21/6245 (20130101) Computer Systems Based on Specific Computational Models G06N 7/00 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/101 (20130101) H04L 63/102 (20130101) H04L 67/12 (20130101) H04L 67/306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095912 | SLOMKA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Piotr SLOMKA (Los Angeles, California); Aakash Shanbhag (San Pedro, California) |
| ABSTRACT | Systems and methods are disclosed for applying attenuation correction to single photon emission computed tomography (SPECT) imaging data for myocardial perfusion imaging (MPI) studies. SPECT-MPI imaging data can be provided to a deep-learning model to automatically generate simulated computed tomography attenuation correction (CT-AC) images from the non-corrected (NC) SPECT-MPI imaging data. These simulated CT-AC images can then be used to perform attenuation correction on the SPECT-MPI imaging data to generate corrected SPECT-MPI imaging data. The deep-learning model can be trained using corresponding pairs of non-corrected SPECT-MPI imaging data and traditional CT-AC imaging data. The deep-learning model can be a conditional generative adversarial neural network (cGAN). |
| FILED | Tuesday, September 12, 2023 |
| APPL NO | 18/367154 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10108 (20130101) G06T 2207/20081 (20130101) G06T 2207/30048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096441 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ludwig Institute for Cancer Research Ltd (Zurich, Switzerland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bing Ren (La Jolla, California); Miao Yu (La Jolla, California); Rongxin Fang (La Jolla, California) |
| ABSTRACT | Methods and kits for genome-wide identification of chromatin interactions in a cell are provided. |
| FILED | Tuesday, November 21, 2023 |
| APPL NO | 18/516098 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096490 | Huseby et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Carol J. Huseby (Tempe, Arizona); Paul Coleman (Fountain Hills, Arizona) |
| ABSTRACT | A processor is configured to implement a machine learning model that is trained to select transcripts in blood for distinguishing neurodegenerative diseases. The algorithm is developed via machine learning and leverages concepts associated with blood-based changes in mRNA gene expression for differentiating patients of any neurodegenerative disease regardless of the proteins or their post-translational modifications occurring in disease. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 18/263503 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/20 (20190101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) G16B 40/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Original (OR) Class G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096493 | Ligorio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| INVENTOR(S) | Matteo Ligorio (Dallas, Texas); Rebecca Napier (Boynton Beach, Florida); William Gasper (Omaha, Nebraska); Dario Ghersi (Omaha, Nebraska) |
| ABSTRACT | Aspects of the present disclosure relate to systems and methods for analyzing a tumor, and more specifically, analyzing a tumor to identify a biological aggressiveness of the tumor. One example method for tumor analysis includes: receiving one or more input features associated with a geometric shape of a tumor, the one or more input features including at least a value indicating a circularity of the tumor; determining, via a machine learning component, a characteristic of the tumor based on the one or more input features, the characteristic being indicative of patient survivability; and outputting an indication of the characteristic. |
| FILED | Monday, September 18, 2023 |
| APPL NO | 18/469022 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/50 (20170101) G06T 2207/20021 (20130101) G06T 2207/20036 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30242 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Original (OR) Class G16H 50/50 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096514 | SHEH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yiauchung SHEH (New York, New York); Gregory AYZENBERG (New York, New York) |
| ABSTRACT | Described herein is a compact cyclotron solid target for radionuclide production. In contrast to other cyclotron solid targets, the compact cyclotron solid target described herein utilizes liquid (e.g., water) cooling flow (in and out) from the front of the target, which clears the back of the solid target of any hanging tubing and connectors which may block load-release the target easily. Having water cool the target from the front considerably reduces the size of the whole solid target mechanism. |
| FILED | Monday, November 27, 2023 |
| APPL NO | 18/520115 |
| CURRENT CPC | Conversion of Chemical Elements; Radioactive Sources G21G 1/10 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/08 (20130101) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097532 | Hadley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | J. Rock Hadley (Salt Lake City, Utah); Dennis L. Parker (Salt Lake City, Utah); Lorne W. Hofstetter (Salt Lake City, Utah); Robb Merrill (Salt Lake City, Utah) |
| ABSTRACT | A mechanically commutated motor (200) configured for use with an external magnetic field (240) is disclosed. The motor (200) includes an axle (208) formed of anon-magnetic material. A rotor (206) is coupled to the axle (208), the rotor (206) including three or more actuator units (205) spaced about the axle (208). Each actuator unit (205) comprises a non-magnetic material, a coil winding (214) along each of the three or more actuator units (205), and a commutator (216) coupled to the axle (208) and electrically associated with the coil windings (214). The motor (200) further includes two or more resilient contacts (210) oriented to direct a current through the commutator (216) to one of the coil windings (214) to induce a current in the coil winding (214) to form an electromagnet that rotates the rotor (206) relative to the external magnetic field (240) from a magnet located external to the mechanically commutated motor (200). |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/257083 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 34/30 (20160201) Dynamo-electric Machines H02K 11/02 (20130101) Original (OR) Class H02K 11/22 (20160101) H02K 11/40 (20160101) H02K 11/0141 (20200801) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/0115 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240090493 | Woodley |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christa M Woodley (Vicksburg, Mississippi) |
| ABSTRACT | One embodiment is directed to an engineered acoustic signal for keeping an aquatic animal away from one or more specific areas. The engineered acoustic signal has deterrence stimulus evaluated to maximize effectiveness in keeping the aquatic animal away from specific areas based on at least one of: ability of the deterrence stimulus to initiate a behavioral response of the animal to keep the animal from the one or more specific areas; duration of the behavioral response; and magnitude of the behavioral response. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/126181 |
| CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 29/18 (20130101) Original (OR) Class Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 15/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240090817 | Weiss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Shennan Aibel Weiss (Philadelphia, Pennsylvania); Zachary Waldman (Philadelphia, Pennsylvania); Michael Sperling (Philadelphia, Pennsylvania) |
| ABSTRACT | A device and a signal processing method that can monitor human memory performance by recognizing and characterizing high-gamma (65-250 Hz) and beta (14-30 Hz) band oscillations in the left Brodmann Area 40 (BA40) of the brain that correspond with the strength of memory encoding or correct recall. The signal processing method detects high-gamma and beta band oscillations in the electrical signals recorded from left BA40, and quantifies the spectral content, power, duration, onset, and offset of the oscillations. The oscillation's properties are used to classify the subject's memory performance on the basis of a comparison with the subject's prior human memory performance and the properties of the corresponding oscillations. A report of the subject's current memory performance can be utilized in a closed loop brain stimulation device that serves the purpose of enhancing human memory performance. |
| FILED | Wednesday, November 15, 2023 |
| APPL NO | 18/510470 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/374 (20210101) Original (OR) Class A61B 5/384 (20210101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36025 (20130101) A61N 1/36171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240090880 | Moga et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tasso, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ben Moga (Soquel, California); Ben Casavant (Seattle, Washington); Erwin Berthier (Seattle, Washington) |
| ABSTRACT | The disclosed apparatus, systems and methods relate to devices, systems and methods for the collection of bodily fluids. The collector can make use of microfluidic networks connected to collection sites on the skin of a subject to gather and shuttle blood into a removable cartridge. The collected fluid is supplied to substrate for drying, storage and transport. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/186114 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/150022 (20130101) A61B 5/150068 (20130101) A61B 5/150251 (20130101) A61B 5/150343 (20130101) A61B 5/150366 (20130101) A61B 10/0038 (20130101) A61B 10/0045 (20130101) Original (OR) Class A61B 10/0096 (20130101) A61B 2503/42 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/5023 (20130101) B01L 2200/18 (20130101) B01L 2300/069 (20130101) B01L 2300/0816 (20130101) B01L 2400/0406 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240090881 | Fischer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory S. Fischer (Worcester, Massachusetts); Hao Su (Worcester, Massachusetts) |
| ABSTRACT | A system for MRI-guided interventional needle procedures comprises a master device providing haptic feedback to and receiving position commands from the operator, a robot controller receiving position commands and providing force information to said master device, a navigation component receiving images from an MRI scanner; said navigation component providing trajectory planning information to said robot controller, a slave robot driving a needle, the slave robot receiving control information from the robot controller, and a fiber optic sensor operatively connected to said slave robot. The fiber optic sensor provides data to the robot controller to provide force information to the master device. The master device, robot controller, navigation component, slave robot and sensor are compatible with an MRI environment and operate inside an MRI scanner room. |
| FILED | Monday, November 27, 2023 |
| APPL NO | 18/519758 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0241 (20130101) Original (OR) Class A61B 34/30 (20160201) A61B 34/37 (20160201) A61B 34/76 (20160201) A61B 90/11 (20160201) A61B 2090/064 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091162 | MARGOLIS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kara MARGOLIS (New York, New York); Mark ANSORGE (New York, New York); Kam W. LEONG (New York, New York); Letao YANG (New York, New York); Yuefei ZHU (New York, New York) |
| ABSTRACT | The present disclosure provides, inter alia, compositions and methods for treating or ameliorating the effect of a disorder such as, e.g., anxiety or depression in a subject, with less or no off- and/or on-target side effects. Also provided are methods for treating such disorder in a pregnant woman. |
| FILED | Monday, November 20, 2023 |
| APPL NO | 18/514903 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/143 (20130101) A61K 9/501 (20130101) Original (OR) Class A61K 9/5115 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091259 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Catherine J. Wu (Brookline, Massachusetts); Giacomo Oliveira (Boston, Massachusetts) |
| ABSTRACT | Disclosed are methods for identifying expanded, exhausted, and tumor-specific T-cell clonotypes for adoptive cell transfer, and methods of cancer treatment and modified T cells with anti-tumor T cell receptors (TCRs). |
| FILED | Friday, July 21, 2023 |
| APPL NO | 18/224865 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091733 | Choi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ODH IP Corp. (NEW YORK, New York) |
| ASSIGNEE(S) | ODH IP Corp. (NEW YORK, New York) |
| INVENTOR(S) | Eugene Choi (Rockville, Maryland); Kersten Rapp (Rockville, Maryland); Greg Hammersmith (Rockville, Maryland); Brian Cregger (Rockville, Maryland) |
| ABSTRACT | This disclosure provides systems and methods for the on-demand synthesis, separation, purification and formulation of chemicals, and particularly for the on-demand production of pharmaceutical products. More particularly, the disclosure provides continuous-flow on-demand systems, comprising one or more reagent holding/dispensing containers, continuous-flow chemical synthesis modules and/or one or more separation, crystallization, filtration, wash and/or formulation modules, additionally comprising automated detection systems and methods for monitoring reagents, products and processing parameters and automated control systems and methods for controlling processing conditions and parameters. |
| FILED | Tuesday, September 05, 2023 |
| APPL NO | 18/461222 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/18 (20130101) Original (OR) Class B01J 2219/00049 (20130101) B01J 2219/00306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091891 | Deluca et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Arlington, Virginia) |
| ASSIGNEE(S) | The Boeing Company (Arlington, Virginia) |
| INVENTOR(S) | Michael J. Deluca (Norristown, Pennsylvania); Matthew H. Cawthorne (Wayne, Pennsylvania); Howard T. Rolleston (Glen Mills, Pennsylvania) |
| ABSTRACT | A method for repairing a crack in a structure includes mounting a manifold to the structure around the crack. The structure has a nonplanar surface contour that surrounds the crack. The manifold has a base portion, a cover portion, and a plug. The base portion has a grip surface configured to conform to the nonplanar surface contour of the structure. The cover portion is connected to the base portion, and has an injection port and a vent port in fluid communication with a channel aligned to the crack. The injection port transfers a bonding material into and out of the channel. The plug closes and opens the vent port. The method includes filling the channel with the bonding material to direct the bonding material into the crack, and draining the bonding material from the manifold. |
| FILED | Tuesday, November 28, 2023 |
| APPL NO | 18/521150 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/002 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 6/04 (20130101) Original (OR) Class Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 73/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092037 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); The United States Of America As Represented By Secretary Of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shu Yang (Blue Bell, Pennsylvania); Lishuai Jin (Philadelphia, Pennsylvania); Daniel J O'Brien (Hydes, Maryland); Michael Yeager (Aberdeen, Maryland) |
| ABSTRACT | A method, comprising: with a cutting graph corresponding to a two-dimensional (2-D) representation of a polyhedral mesh that is representative of the 3-D target object, forming i sheets in conformity with the cutting graph, i being from 1 to n, an i-th 2-D sheet having an i-th set of cuts formed therein, an (i+1)-th 2-D sheet having a (i+1)-th set of cuts formed therein, the (i+1)-th set of cuts optionally differing from the i-th set of cuts. A 3-D composite object having a surface, the 3-D composite object comprising: i stacked and consolidated sheets, i being from 1 to n, an i-th sheet having an i-th set of cuts formed therein, an (i+1)-th sheet having a (i+1)-th set of cuts formed therein, the (i+1)-th set of cuts optionally differing from the i-th set of cuts. |
| FILED | Thursday, February 23, 2023 |
| APPL NO | 18/173243 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/222 (20130101) Original (OR) Class Electric Digital Data Processing G06F 30/17 (20200101) G06F 2119/18 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092481 | Mulligan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HYDRONALIX, INC. (Green Valley, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anthony C. Mulligan (Sahuarita, Arizona); Lloyd Vincent Mulligan (Green Valley, Arizona); Jaime Lara-Martinez (Tucson, Arizona); Jay M. Cohen (Virginia Beach, Virginia); Drey Dean Platt (Sahuarita, Arizona); Dylan Kylar Allen Gutierrez (Tucson, Arizona); Eva Marie Huie (Tucson, Arizona); Robert W. Lautrup (Oakton, Virginia); Ronald A. Cipriani (Green Valley, Arizona) |
| ABSTRACT | A propeller according to an embodiment includes a hub and a series of blades extending outward from the hub. Each blade of the series of blades includes a core and a skin covering the core. The core may be formed of a ceramic first material and the skin is formed of a second material different than the ceramic first material. The ceramic first material of the core may be ceramic Si3N4 (silicon nitride), yttria-toughened zirconia ceramic, or alumina-zirconia ceramic, and the second material of the skin may be a polymer. The polymer skin is configured to function as a shock absorber protecting the ceramic core, and the ceramic core is configured to provide rigidity to maintain the shape of the propeller blades under aerodynamic loading, which enables improved aerodynamic efficiency and reduced noise generation. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/932929 |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/08 (20130101) B63G 2008/005 (20130101) Marine Propulsion or Steering B63H 1/20 (20130101) Original (OR) Class B63H 1/26 (20130101) Aeroplanes; Helicopters B64C 11/20 (20130101) B64C 39/024 (20130101) B64C 2201/108 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092767 | Palmese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania); The Government of the United States of America, as represented by The Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania); The Government of the United States of America, as represented by The Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Giuseppe R. Palmese (Hainesport, New Jersey); Santosh K. Yadav (Geneva, Ohio); John J. LaScala (Wilmington, Delaware) |
| ABSTRACT | Benzoxazine compounds, methods of making them, polymers made therefrom and methods of polymerizing the benzoxazines. These renewable benzoxazine monomers and polymers that utilize the variety of building blocks found in renewable plant biomass, demonstrate excellent processability and large temperature windows for processing of resin systems. |
| FILED | Friday, March 24, 2023 |
| APPL NO | 18/189286 |
| CURRENT CPC | Heterocyclic Compounds C07D 307/52 (20130101) C07D 413/06 (20130101) Original (OR) Class C07D 413/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/024 (20130101) C08G 73/0273 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092809 | Evans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Austin Michael Evans (Evanston, Illinois); William Robert Dichtel (Evanston, Illinois); Mark C. Hersam (Evanston, Illinois); Vinod Kumar Sangwan (Evanston, Illinois); Ioannina Castano (Evanston, Illinois); Patrick E. Hopkins (Charlottesville, Virginia); Ashutosh Giri (Charlottesville, Virginia) |
| ABSTRACT | Disclosed herein are low dielectric constant (low-k) two-dimensional covalent organic framework materials that have a dielectric constant k less than 2.4, optionally less than 1.9, and are comprised of regularly porous, covalently linked, layer structures. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 18/262537 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 28/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092841 | Matoba |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nobuyuki Matoba (Owensboro, Kentucky) |
| ABSTRACT | The treatment of growth factor receptor-mediated cancers, such as epidermal growth factor receptor- (EGFR-) and/or insulin-like growth factor 1 receptor- (IGF1R-) mediated cancers, e.g., lung cancer such as non-small cell lung cancer, which is sensitive to polypeptides specifically binds a high-mannose-type glycan epitope, is described. Methods for reducing activation of EGFR and/or IGF1R in cancer cells, inhibiting cancer cell migration, treatment of cancer and/or reduction of tumor growth in subjects (e.g., human patients) are provided. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 18/261950 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092945 | PATRICK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason PATRICK (Raleigh, North Carolina); Zachary PHILLIPS (Raleigh, North Carolina); Sherif Aboubakr (Raleigh, North Carolina); William MARTIN (Raleigh, North Carolina) |
| ABSTRACT | In one aspect, the disclosure relates to self-healing systems including at least a structural polymer, a plurality of optical fibers or polymer waveguides embedded in the structural polymer, and a plurality of micro-channels through the structural polymer, wherein the micro-channels are configured to deliver a curing composition to at least one site of damage in the system. In another aspect, the curing composition can include a photo-polymerizable liquid monomer, and, optionally, a sensitizer, a photo-initiator, and/or a toughening agent, articles comprising the same, and methods of in situ self-healing of damage including Mode-I fractures using visible irradiation from the optical fibers or polymer waveguides to photo-polymerize the liquid monomer. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/467968 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/48 (20130101) Original (OR) Class Compositions of Macromolecular Compounds C08L 23/06 (20130101) C08L 23/12 (20130101) C08L 33/12 (20130101) C08L 71/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02 (20130101) G02B 6/10 (20130101) G02B 2006/12035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092965 | Azoulay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jason D. Azoulay (Atlanta, Georgia); Lifeng Huang (Hattiesburg, Mississippi); Alexander E. London (Hattiesburg, Mississippi); Naresh Eedugurala (Hattiesburg, Mississippi) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN MISSISSIPPI (HATTIESBURG, Mississippi) |
| INVENTOR(S) | Jason D. Azoulay (Atlanta, Georgia); Lifeng Huang (Hattiesburg, Mississippi); Alexander E. London (Hattiesburg, Mississippi); Naresh Eedugurala (Hattiesburg, Mississippi) |
| ABSTRACT | The invention provides for polymer structures and their preparation and resulting novel functionalities including open-shell character and high intrinsic conductivity with wide-range tenability. Electrical conductivity can be further modulated by introducing or blending with materials, fillers, dopants, and/or additives. The materials or resultant composites of the invention can be processed by various techniques into different forms to realize multiple applications. |
| FILED | Tuesday, August 08, 2023 |
| APPL NO | 18/366977 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/126 (20130101) Original (OR) Class C08G 2261/18 (20130101) C08G 2261/122 (20130101) C08G 2261/148 (20130101) C08G 2261/414 (20130101) C08G 2261/514 (20130101) C08G 2261/1646 (20130101) C08G 2261/3223 (20130101) C08G 2261/3225 (20130101) C08G 2261/3241 (20130101) C08G 2261/3243 (20130101) C08G 2261/3246 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2365/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/041 (20170501) C08K 2201/001 (20130101) C08K 2201/011 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/16 (20130101) H01B 1/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093076 | So et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher R. So (Alexandria, Virginia); Michael C. Wilson (Alexandria, Virginia) |
| ABSTRACT | Adhesive formulations comprising bovine serum albumin, b-lactoglobulin, and/or a-lactalbumin can be applied and cured underwater to form a strong adhesive. Curing can be accomplished using heat or via a chemical denaturing component. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/368841 |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 11/06 (20130101) C09J 189/00 (20130101) Original (OR) Class C09J 2203/35 (20200801) C09J 2301/408 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093109 | Son et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven F. Son (West Lafayette, Indiana); Caleb Nathaniel Harper (Omaha, Nebraska); Ryan Tolman Merrell (West Lafayette, Indiana); Andrew Ryan Noel (Granbury, Texas); Dhruval Natubhai Patel (West Lafayette, Indiana) |
| ABSTRACT | The solvated metal particle-coating system includes a metal additive and a polar outer-sphere electron transferring solvent. The metal additive is solvated in the polar outer-sphere electron transferring solvent. The polar outer-sphere electron transferring solvent may include liquid ammonia, methylamine, and/or hexamethylphosphoramide. The metal additive may include an alkali metal and/or an alkaline earth metal. The solvated metal additive within the polar outer-sphere electron transferring solvent may be used to coat a metal particle and/or a metalloid particle as a layer. As the polar outer-sphere electron transferring solvent evaporates, the solvated metal additive is coupled to the metal particle and/or the metalloid particle. |
| FILED | Friday, June 02, 2023 |
| APPL NO | 18/205032 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/10 (20220101) B22F 1/17 (20220101) B22F 1/145 (20220101) B22F 2301/052 (20130101) B22F 2301/054 (20130101) B22F 2998/10 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 5/40 (20130101) Original (OR) Class C10L 2290/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093174 | Semprini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon); North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon); North Carolina State Univeristy (Raleigh, North Carolina) |
| INVENTOR(S) | Lewis Semprini (Corvallis, Oregon); Mitchell Rasmussen (Corvallis, Oregon); Michael R. Hyman (Raleigh, North Carolina) |
| ABSTRACT | Certain disclosed embodiments concern a bioremediation composition comprising microbial cells, at least one co-metabolism substrate to induce selected enzyme production by the microbial cells, and a bead or gel encapsulating the microbial cells, such as bacterial or fungi cells, and the at least one co-metabolism substrate. For certain embodiments, the substrate is a slow release compound, such as an orthosilicate that hydrolyzes to produce an alcohol growth substrate. Embodiments of a method for using the composition to transform contaminants of concern also are disclosed. |
| FILED | Tuesday, November 07, 2023 |
| APPL NO | 18/503854 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/025 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/20 (20130101) C12N 9/0071 (20130101) C12N 11/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240093190 — ENGINEERED NUCLEIC ACIDS TARGETING LONG NONCODING RNA INVOLVED IN PATHOGENIC INFECTION
| US 20240093190 | Si et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Longlong Si (Cambridge, Massachusetts); Haiqing Bai (Cambridge, Massachusetts); Rachelle Pranti-Baun (Cambridge, Massachusetts); Donald E. Ingber (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides compositions and methods for inhibiting viral pathogenesis by targeting long noncoding ribonucleic acids. |
| FILED | Tuesday, January 18, 2022 |
| APPL NO | 18/272933 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/113 (20130101) C12N 2320/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093200 | JUNGHANS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tufts Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard P. JUNGHANS (Boston, Massachusetts); Mumtaz YASEEN (West Roxbury, Massachusetts) |
| ABSTRACT | Provided herein are compositions and methods for improving immune system function. In particular, provided herein are compositions, methods, and uses of YY1 and EZH2 inhibitors for preventing and reversing T-cell exhaustion (e.g., for use in immunotherapy). |
| FILED | Tuesday, February 21, 2023 |
| APPL NO | 18/171891 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/444 (20130101) A61K 31/496 (20130101) A61K 31/706 (20130101) A61K 31/713 (20130101) A61K 31/4439 (20130101) A61K 31/5377 (20130101) A61K 31/7088 (20130101) A61K 31/7105 (20130101) A61K 35/17 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) A61P 35/00 (20180101) A61P 37/04 (20180101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1007 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) Enzymes C12Y 201/01043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093208 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ting Lu (Savoy, Illinois); Wentao Kong (Champaign, Illinois) |
| ABSTRACT | Provided herein are systems that provide a genetic program to control bacterial life cycle and function execution, thereby conferring programmable microbial transition between planktonic and biofilm states and facilitating the development of cellular functions across physiological domains. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/463837 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/22 (20130101) C12N 9/0071 (20130101) C12N 9/2417 (20130101) C12N 9/2471 (20130101) C12N 15/11 (20130101) C12N 15/74 (20130101) C12N 15/635 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2509/00 (20130101) C12N 2800/80 (20130101) C12N 2800/101 (20130101) C12N 2830/002 (20130101) C12N 2830/005 (20130101) Enzymes C12Y 114/14 (20130101) C12Y 302/01001 (20130101) C12Y 302/01023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093285 | ELLINGTON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew ELLINGTON (Austin, Texas); Sanchita BHADRA (Austin, Texas); Jared ELLEFSON (Tucson, Arizona); Jimmy GOLLIHAR (Boston, Massachusetts); Arti POTHUKUCHY (Austin, Texas); Michelle BYROM (Austin, Texas); Raghav SHROFF (Austin, Texas) |
| ABSTRACT | Disclosed herein is a method of utilizing an enzyme in a nucleic acid manipulation process, the method comprising: a) transforming a microorganism with a non-native enzyme; b) inducing expression of the enzyme in the microorganism, thereby producing the non-native enzyme; c) adding the microorganism of step b) directly to a non-naturally occurring nucleic acid manipulation process, wherein the non-native enzyme is not purified from the microorganism prior to addition to the nucleic acid manipulation process; and carrying out the nucleic acid manipulation process using the enzyme. Importantly, this method can be carried out without the need to purify the enzyme from the cell producing it before it is used in the nucleic acid manipulation method. Also disclosed herein is a kit for carrying out a nucleic acid manipulation process, the kit comprising a) a microorganism expressing a non-native enzyme; b) nucleic acids of interest; and c) reagents for use in the nucleic acid manipulation process. |
| FILED | Tuesday, October 03, 2023 |
| APPL NO | 18/376018 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093387 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army DEVCOM, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rongzhong Jiang (Olney, Maryland); Jiangtian Li (Ellicott City, Maryland); Deryn D. Chu (Potomac, Maryland); David R. Baker (Silver Spring, Maryland) |
| ABSTRACT | An alkaline electrolyte membrane (AEM) electrolytic device is designed, assembled and evaluated for water electrolysis, composed of an anode for oxygen generation, a cathode for hydrogen generation, an AEM for anion conductive, and two internal water gas separators (IWGSs) for water supplying to the anode and the cathode, respectively, as well as for automatically separation of water and gas produced from the anode or from the cathode. There is no need of pumps for water and gas circulations and no external water gas separators (EWGSs) that are used by conventional water electrolyzers. The corrosive electrolyte is confined in the water containers and will not damage other parts in the electrolytic device. Furthermore, novel multi gas diffusion layers are used to replace the conventional single gas diffusion layer. The pore size is configurable to improve the mass transfer of electrochemical reactions and promote electrochemical reactions. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/947797 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 9/21 (20210101) Original (OR) Class C25B 11/063 (20210101) C25B 11/093 (20210101) C25B 13/02 (20130101) C25B 13/05 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093424 | BORISKINA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUT OD TECHNOLOGY (Cambridge, Massachusetts); POLITECNICO DI TORINO (Torino, Italy); INSTITUTO TECHNOLOGICO Y DE ESTUDIOS SUPERIORES DE MONTERREY (Monterrey, N.L., C.P., Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Svetlana V. BORISKINA (Winchester, Massachusetts); Gang CHEN (Cambridge, Massachusetts); Luis Marcelo LOZANO SANCHEZ (Cambridge, Morocco); Matteo ALBERGHINI (Turin, Italy) |
| ABSTRACT | The present disclosure generally relates to textiles that are optimized to maximize moisture wicking and evaporative performance thereof. In some embodiments, raw polyethylene (PE) powder can be extruded into fibers that can be modified by oxidation along a surface thereof to increase hydrophilicity of the surface. Once sufficiently oxidized, the fibers can be bundled to form multi-filament yarns that can then be spun, weaved, knitted, and/or otherwise associated with one another to form a polyethylene fabric. The PE fibers can be further modified to increase a capillary force of the bundle, thereby further increasing hydrophilicity of the resulting fabric. Engineering of the capillary force can be performed by optimizing one or more of a fiber size, a density, or a cross-section of the fibers and/or the bundles. The resultant fabric can exhibit a strong weight reduction, stain resistance, and drying capabilities, among other capabilities. |
| FILED | Thursday, January 20, 2022 |
| APPL NO | 18/260929 |
| CURRENT CPC | Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 10/001 (20130101) Original (OR) Class D06M 10/025 (20130101) D06M 2101/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093653 | Rajamani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rajesh Rajamani (Saint Paul, Minnesota); Woongsun Jeon (Seoul, South Korea) |
| ABSTRACT | A method of estimating in-cylinder pressure includes receiving a vibration signal from a vibration sensor mounted proximate a compression ignition (CI) engine, receiving angular position information for the CI engine, and determining in-cylinder pressure based on the angular position information and on a combustion component of the vibration signal. |
| FILED | Tuesday, September 12, 2023 |
| APPL NO | 18/465387 |
| CURRENT CPC | Controlling Combustion Engines F02D 35/023 (20130101) Original (OR) Class F02D 35/027 (20130101) F02D 41/062 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/334 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093718 | Shundo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ken Shundo (Fort Worth, Texas); Ryan A. Smith (Fort Worth, Texas); Bryan K. Baskin (Arlington, Texas) |
| ABSTRACT | A coupling system is described that allows users to avoid having to manipulate two tools at the same time while reaching around to both sides of the coupled components. A lock plate can rest above one or more holes passing through (and for joining together) the components. A blade pin with a partially hollow cylinder can be inserted through holes in the lock plate and at least partially through the holes. A blade bolt can be inserted into the holes and the cylinder from the other side. The blade bolt can comprise an o-ring that engages with an inner diameter of a portion of the cylinder and holds the parts together with an interference fit. A portion of the bolt can extend through the top of the holes, and a washer and nut can be attached to or about a threaded portion of the bolt. During each state of installation a user will not have to reach to both sides of the system while manipulating multiple tools. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/947392 |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 39/04 (20130101) F16B 39/101 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093964 | Beaman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard O. Beaman (Tucson, Arizona); Dmitry V. Knyazev (Tucson, Arizona); Peter D. Dunning (Tucson, Arizona) |
| ABSTRACT | A launcher for launching a flying vehicle, such as a projectile or missile, includes a cutter for cutting a line, such as an umbilical line, that is coupled to the vehicle prior to launch. An example of a line is a tube for providing cooling for onboard components of the vehicle, such as a seeker of the vehicle. The cutter may be part of a mount of the launcher for mounting the line and other components, such as a compressor. The cutter may be configured so that as the vehicle translates relative to the launcher during the initiation of launch, the line moves against the cutter, severing the line. The cutter may retract after severing the line, for example being pulled away from the vehicle (and into the mount) by a spring mechanism. |
| FILED | Tuesday, September 13, 2022 |
| APPL NO | 17/931657 |
| CURRENT CPC | Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns F41F 3/055 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094103 | Salem et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MRL MATERIALS RESOURCES LLC (Xenia, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ayman A. Salem (Beavercreek, Ohio); Michelle Harr (Xenia, Ohio); Adam Pilchak (Xenia, Ohio); Daniel P. Satko (Centerville, Ohio) |
| ABSTRACT | A process for testing material samples comprises stressing samples under test by bending the samples with a bending fatigue system. During testing, an optical system takes images of the samples and cracks are identified in the samples using the images. Input variables and spatial variables for use in microstructure analysis of the images are determined and used to create a model. Based on the model, crack growth rates are predicted for untested microstructures based on the samples based on the analysis of the images. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/174507 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/20 (20130101) Original (OR) Class G01N 3/068 (20130101) G01N 2203/0066 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0455 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094297 | Kabra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); CFD Research Corporation (HUNTSVILLE, Alabama) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Venkatesh Kabra (West Lafayette, Indiana); Partha Mukherjee (West Lafayette, Indiana); James Cole (Huntsville, Alabama); Paul Northrop (Huntsville, Alabama); Conner Fear (Glen Ellen, California) |
| ABSTRACT | A state of battery testing system is disclosed which includes a charger, a load to be coupled across the battery's positive and negative terminals, a processer adapted to apply a predetermined voltage pulse across the battery's positive and negative terminals, apply the load to the battery, measure and log current through the load as Iexp, and establish a model based on establishing an initial estimation of state of the battery (θ0), and establishing a modeled state of battery (θi) based on a plurality of internal parameters of the battery. The model is adapted to output a model current through the load, inputting θ0 and the plurality of internal parameters of the model to thereby generate Imodel, generate an objective function (f) based on a comparison of Imodel and Iexp, and iteratively optimize θi, and output θoptimal based on the iterations. |
| FILED | Tuesday, May 23, 2023 |
| APPL NO | 18/201043 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/367 (20190101) G01R 31/392 (20190101) G01R 31/3648 (20130101) Original (OR) Class G01R 31/3842 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094425 | Amatucci et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | William E. Amatucci (Fairfax, Virginia); Gurudas I. Ganguli (Arlington, Virginia); Abhijit Sen (Ahmedabad,, India); Christopher Crabtree (Springfield, Virginia) |
| ABSTRACT | A detector for detecting optically undetectable sub-cm orbital debris. A ring detector comprising a current pulse transformer (CPT) in which a conducting wire coil is wrapped around a loop of high permeability material having a magnetic nanoparticle (MNP) core. Debris objects in low earth orbit become charged as they pass through local plasma. As each charged debris object passes through the coil-wrapped loop, its current generates an induced voltage pulse, which can be used to detect the presence of the debris object. By fielding such a detector on a satellite, a long duration survey of the debris distribution in the LEO region can be made as the satellite's altitude is systematically varied. |
| FILED | Friday, March 03, 2023 |
| APPL NO | 18/178036 |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 3/10 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/24 (20130101) H01F 27/306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094438 | Engheta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nader Engheta (Berwyn, Pennsylvania); Kathleen J Stebe (Penn Valley, Pennsylvania); Nasim Mohammadi Estakhri (Anaheim, California); Tianyi Yao (Exton, Pennsylvania); Jed-Joan Edziah (Newark, New Jersey) |
| ABSTRACT | Provided are new classes of reconfigurable, multistable metasurfaces using the physics of colloids confined within nematic liquid crystals (NLCs). The colloids are physically moved from one stable location to another as defined by NLC-colloid interactions by external switching fields. These colloids can be scatterers within reconfigurable metasurfaces with electromagnetic (EM) responses that change with colloid location. because the colloids are moved between stable loci, these metasurfaces are also multistable, and require energy input only when changing colloid position. Furthermore, because the colloids can be returned to their original positions by simply reversing the switching field, all changes in EM responses are entirely reversible. Also provided are reconfigurable, multistable metasurfaces that utilize colloids disposed within a field of protrusions extended from a surface, with interactions between the colloid and the protrusions and the application of external fields operating to move the colloids between stable states. |
| FILED | Wednesday, September 06, 2023 |
| APPL NO | 18/461750 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/13756 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094439 | RUBIN et al. |
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| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Noah A. RUBIN (Cambridge, Massachusetts); Mohammad Aun Abbas ZAIDI (Cambridge, Massachusetts); Federico CAPASSO (Cambridge, Massachusetts) |
| ABSTRACT | An optical component can include a substrate. The optical component can include a metasurface disposed on the substrate. The metasurface can include one or more linearly birefringent elements. A spatially-varying Jones matrix and a far-field of the metasurface can define a transfer function of the metasurface configured to generate a controlled response in the far-field according to polarization of light incident on the metasurface. |
| FILED | Monday, December 27, 2021 |
| APPL NO | 18/269939 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/08 (20130101) Original (OR) Class G02B 5/32 (20130101) G02B 5/3083 (20130101) G02B 27/286 (20130101) G02B 27/4261 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095184 | Gutierrez |
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| FUNDED BY |
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| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Anthony Thomas Gutierrez (Seattle, Washington) |
| ABSTRACT | Address translation service management techniques are described. These techniques are based on metadata that is usable to provide a hint as insight into memory access, and based on this, use of a translation lookaside buffer is optimized to control which entries are maintained in the queue and manage address translation requests. |
| FILED | Wednesday, September 21, 2022 |
| APPL NO | 17/949716 |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0882 (20130101) G06F 12/1027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095341 | VENKATARAMANI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Guru Prasadh V. VENKATARAMANI (Fairfax, Virginia); Preet Derasari (Alexandria, Virginia); Kailash Gogineni (Alexandria, Virginia) |
| ABSTRACT | A hardware framework for cyber-deception operations provides flexibility in formulating counterattacks and leverages hardware support for efficiency. Hardware-assisted deception primitives are provided at kernel crossing boundaries to privileged system features that propel the security defenses to dynamically manipulate the malware execution and present a deceptive view of the system state to the attackers. Malware may be in the form of various attack vectors including ransomware, infostealers, buffer overflow, and side-channels. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109733 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/54 (20130101) Original (OR) Class G06F 21/564 (20130101) G06F 21/568 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095381 | SADEH et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Norman SADEH (Pittsburgh, Pennsylvania); Bin LIU (Pittsburgh, Pennsylvania); Anupam DAS (Pittsburgh, Pennsylvania); Martin DEGELING (Pittsburgh, Pennsylvania); Florian SCHAUB (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system comprises a IoT resource and a computing device of a user. The computing device comprises a processor that executes a personal privacy app that receives data about the IoT resource and communicates a preference setting for the user with respect to the IoT device. The preference setting is based on the data received about the IoT resource. |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/239267 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/604 (20130101) Original (OR) Class G06F 21/629 (20130101) G06F 21/6245 (20130101) Computer Systems Based on Specific Computational Models G06N 7/00 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/101 (20130101) H04L 63/102 (20130101) H04L 67/12 (20130101) H04L 67/306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095569 | Hays et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Max Hays (New Haven, Connecticut); Michel Devoret (New Haven, Connecticut) |
| ABSTRACT | Techniques are described for detecting when background radiation has impacted a qubit without the need for additional hardware. In particular, a quantum system may operate readout hardware to read the state of a qubit in addition to operating the readout hardware to detect when an impact has occurred. Readouts from impacted qubits can then be ignored during error correction, and those qubits reset for subsequent operations. In some cases, a readout resonator coupled to a qubit can be implemented as a readout resonator with a high kinetic inductance. |
| FILED | Tuesday, September 12, 2023 |
| APPL NO | 18/465433 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095856 | Subrahmanian et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Venkatramanan Subrahmanian (Evanston, Illinois); Dongkai Chen (Mountain View, California); Haipeng Chen (Williamsburg, Virginia); Deepti Poluru (Hanover, New Hampshire); Almas Abdibayev (Hanover, New Hampshire) |
| ABSTRACT | A computer-implemented method, system and computer program product for generating fake documents. A corpus of domain specific documents is built and word embeddings for each word in such documents are identified as embed-ding vectors. Concepts in the corpus are then clustered together by clustering the embedding vectors. A feasible candidate replacement set is generated for each concept using the clustered concepts in the corpus. After such pre-processing steps are accomplished, concepts are extracted from a document. The concept importance values are computed for these extracted concepts, in which the extracted concepts are clustered into bins based on such measurements. A joint optimization problem is solved to identify both the concepts in the document to be replaced using the clustered concepts in the bins as well as the corresponding replacement concepts obtained from the clustered concepts in the corpus. Such replacements are made to generate a fake document. |
| FILED | Monday, December 27, 2021 |
| APPL NO | 18/270690 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/355 (20190101) G06F 40/40 (20200101) G06F 40/166 (20200101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/184 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095891 | Saha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert Bosch GmbH (Stuttgart, Germany) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aniruddha Saha (Elkridge, Maryland); Chaithanya Kumar Mummadi (Pittsburgh, Pennsylvania); Wan-Yi Lin (Wexford, Pennsylvania); Filipe Condessa (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system and method include dividing a source image into a plurality of source regions, which are portions of the source image that correspond to a plurality of grid regions. A mask is used to create a first masked region that masks a first source region and a first unmasked region that comprises a second source region. A first inpainted region is generated by inpainting the first masked region based on the second source region. Similarity data is generated based on a similarity assessment. A protected image is generated that includes at least (i) the first masked region at a first grid region when the similarity data indicates that the first source region is not similar to the first inpainted region and (ii) the first inpainted region at the first grid region when the similarity data indicates that the first source region is similar to the first inpainted region. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 17/949003 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/005 (20130101) Original (OR) Class G06T 7/11 (20170101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/761 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096085 | WALAWALKAR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Devesh WALAWALKAR (Pittsburgh, Pennsylvania); Marios SAVVIDES (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein is a method for efficiently reducing the computational footprint of any AI-based object detection model, so as to enable its real-time deployment on computing resource-limited (i.e., low-power, embedded) devices. The disclosed method provides a step-by-step framework using an optimized combination of compression techniques to effectively compress any given AI-based object detection model. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 18/266734 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/082 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/87 (20220101) Original (OR) Class G06V 10/774 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240096120 — System and Method with Masking for Certified Defense Against Adversarial Patch Attacks
| US 20240096120 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert Bosch GmbH (Stuttgart, Germany) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shuhua Yu (Pittsburgh, Pennsylvania); Aniruddha Saha (Elkridge, Maryland); Chaithanya Kumar Mummadi (Pittsburgh, Pennsylvania); Wan-Yi Lin (Wexford, Pennsylvania) |
| ABSTRACT | A computer-implemented system and method relate to certified defense against adversarial patch attacks. A set of one-mask images is generated using a first mask at a set of predetermined regions of a source image. The source image is obtained from a sensor. A set of one-mask predictions is generated, via a machine learning system, based on the set of one-mask images. A first one-mask image is extracted from the set of one-mask images. The first one-mask image is associated with a first one-mask prediction that is identified as a minority amongst the set of one-mask predictions. A set of two-mask images is generated by masking the first one-mask image using a set of second masks. The set of second masks include at least a first submask and a second submask in which a dimension of the first submask is less than a dimension of the first mask. A set of two-mask predictions is generated based on the set of two-mask images. Class data, which classifies the source image, is selected based on the set of two-mask predictions. |
| FILED | Wednesday, September 21, 2022 |
| APPL NO | 17/949980 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/22 (20220101) G06V 10/267 (20220101) G06V 10/764 (20220101) G06V 20/52 (20220101) G06V 20/95 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096618 | Razeghi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Manijeh Razeghi (Wilmette, Illinois) |
| ABSTRACT | Methods of forming κ-phase gallium oxide materials are provided, including highly conductive and highly phase stable such materials. In embodiments, the method comprises exposing a surface of a substrate positioned in a metalorganic chemical vapor deposition (MOCVD) reactor to a gallium (Ga) precursor vapor, an indium (In) precursor vapor, an oxygen (O) precursor vapor, and a silicon (Si) precursor vapor, under conditions to form a κ-phase gallium oxide material on the surface of the substrate. The κ-phase gallium oxide material comprises Ga, O, Si, and further comprises no more than 0.1 weight % In. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 18/277269 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/40 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02565 (20130101) Original (OR) Class H01L 29/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096809 | Tanaka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Hiroki Tanaka (Gilbert, Arizona); Robert Alan May (Chandler, Arizona); Onur Ozkan (Scottsdale, Arizona); Ali Lehaf (Chandler, Arizona); Steve Cho (Chandler, Arizona); Gang Duan (Chandler, Arizona); Jieping Zhang (Mesa, Arizona); Rahul N. Manepalli (Chandler, Arizona); Ravindranath Vithal Mahajan (Chandler, Arizona); Hamid Azimi (Paradise Valley, Arizona) |
| ABSTRACT | Microelectronic assemblies, related devices and methods, are disclosed herein. In some embodiments, a microelectronic assembly may include a substrate having a surface including first conductive contacts and second conductive contacts, wherein the first conductive contacts have a first thickness and the second conductive contacts have a second thickness different than the first thickness; a first microelectronic component having third conductive contacts, wherein respective ones of the third conductive contacts are coupled to respective ones of the first conductive contacts by first interconnects, wherein the first interconnects include solder having a thickness between 2 microns and 35 microns; and a second microelectronic component having fourth conductive contact, wherein respective ones of the fourth conductive contacts are coupled to respective ones of the second conductive contacts by second interconnects, wherein the second interconnects include solder having a thickness between 5 microns and 50 microns. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/932624 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/4857 (20130101) H01L 23/3121 (20130101) H01L 23/5383 (20130101) H01L 23/5386 (20130101) Original (OR) Class H01L 24/13 (20130101) H01L 24/14 (20130101) H01L 24/16 (20130101) H01L 24/19 (20130101) H01L 24/20 (20130101) H01L 24/32 (20130101) H01L 25/50 (20130101) H01L 25/0652 (20130101) H01L 25/0655 (20130101) H01L 2224/19 (20130101) H01L 2224/211 (20130101) H01L 2224/1403 (20130101) H01L 2224/2201 (20130101) H01L 2224/13082 (20130101) H01L 2224/16238 (20130101) H01L 2224/32225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097016 | Fiorenza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Analog Devices, Inc. (Wilmington, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James G. Fiorenza (Carlisle, Massachusetts); Daniel Piedra (Somerville, Massachusetts); Joshua Andrew Perozek (Somerville, Massachusetts) |
| ABSTRACT | Integrated circuits can include compound semiconductor devices having conductive components that control electrical characteristics of the compound semiconductor devices. In one or more examples, one or more conductive components can be located to increase the concentration of electrons in relation to a source electrical contact or a drain electrical contact. In one or more additional examples, a conductive component can be located to reduce the concentration of electrons in relation to a gate electrical contact. The compound semiconductor devices can include a number of compound semiconductor layers that include one or more materials having at least one Group 13 element and at least one Group 15 element. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 18/039919 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/207 (20130101) H01L 29/0843 (20130101) H01L 29/7783 (20130101) Original (OR) Class H01L 29/7786 (20130101) H01L 29/41766 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097064 | Koehler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew D. Koehler (Alexandria, Virginia); Travis J. Anderson (Alexandria, Virginia); Geoffrey M. Foster (Woodbridge, Virginia); Karl D. Hobart (Alexandria, Virginia); Francis J. Kub (Arnold, Maryland); Michael A. Mastro (Fairfax, Virginia) |
| ABSTRACT | A light controlled semiconductor switch (LCSS), method of making, and method of using are provided. In embodiments, a vertical LCSS includes: a semiconductor body including a photoactive layer of gallium nitride (GaN) doped with carbon; a first electrode in contact with a first surface of the semiconductor body, the first electrode defining an area through which light energy from at least one light source can impinge on the first surface; and a second electrode in contact with a second surface of the semiconductor body opposed to the first surface, wherein the vertical LCSS is configured to switch from a non-conductive off-state to a conductive on-state when the light energy impinging on the semiconductor body is sufficient to raise electrons within the photoactive layer into a conduction band of the photoactive layer. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/463540 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) Original (OR) Class H01L 31/102 (20130101) H01L 31/0336 (20130101) H01L 31/1852 (20130101) H01L 31/1856 (20130101) H01L 31/03042 (20130101) H01L 31/03044 (20130101) Pulse Technique H03K 17/785 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097329 | Buchanan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kristopher Buchanan (San Diego, California); Timi Adeyemi (San Diego, California); Carlos F. Flores Molina (San Diego, California); Sara Wheeland (San Diego, California) |
| ABSTRACT | An antenna arrangement has radiation modes for antennas distributed across a geometrical shape, which is a bounded volume in three dimensions or a conformal surface of the bounded volume. A signal network couples between an electrical signal and the antennas with a taper along a selected dimension selected from the three dimensions of the bounded volume. The taper is specified by a selected dimension and a selected mode, which is selected from the radiation modes. Basis polynomials are indexed over the radiation modes and a specified basis polynomial is indexed at the selected mode. The specified basis polynomial gives the taper of an amplitude of the electrical signal at each of the antennas. An operating method determines a respective array factor for each distinct combination of one of the three dimensions and one of the radiation modes, and then selects the distinct combination with a desired array factor. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/946846 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/34 (20130101) H01Q 3/28 (20130101) H01Q 3/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097341 | Boryssenko |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SI2 Technologies, Inc. (North Billerica, Massachusetts) |
| ASSIGNEE(S) | SI2 Technologies, Inc. (North Billerica, Massachusetts) |
| INVENTOR(S) | Anatoliy Boryssenko (Belchertown, Massachusetts) |
| ABSTRACT | Antenna elements are described that may include a radiator, a feeding portion, a first impedance transformer, a balun, and a second impedance transformer. The first impedance transformer, balun, and second impedance transformer may be disposed above a ground plane of an antenna array to reduce a bulk of the array. The array can also include a dielectric top layer for loading apertures of the antenna array. The antenna elements can also include anomaly suppressors can be provided to cancel common-mode resonances from the radiators. |
| FILED | Wednesday, November 22, 2023 |
| APPL NO | 18/517145 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 9/16 (20130101) Original (OR) Class H01Q 9/065 (20130101) H01Q 21/0006 (20130101) H01Q 21/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097404 | Mawst et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Luke J. Mawst (Sun Prairie, Wisconsin); Thomas L. Earles (Verona, Wisconsin); Christopher A. Sigler (Dayton, Ohio); Dan Botez (Madison, Wisconsin) |
| ABSTRACT | Single-mode quantum cascade semiconductor lasers are provided. The lasers comprise a laser element, the laser element comprising a quantum cascade active layer; an upper cladding layer over the quantum cascade active layer; and a lower cladding layer under the quantum cascade active layer, wherein the quantum cascade active layer, the upper cladding layer and the lower cladding layer define a guided optical mode. The quantum cascade active layer and the upper and lower cladding layers are shaped in the form of a ridge structure having a front face, a back face opposite the front face, and a lasing face through which laser emission exits the ridge structure, the ridge structure configured such that the laser emission has a single-lobe, far-field beam pattern from the ridge structure comprising certain sections, including tapered sections, collateral sections, or both. |
| FILED | Thursday, September 24, 2020 |
| APPL NO | 17/768052 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/1039 (20130101) H01S 5/1064 (20130101) H01S 5/1228 (20130101) H01S 5/1246 (20130101) H01S 5/3402 (20130101) Original (OR) Class H01S 2301/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240098451 | Kassas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zak Kassas (Columbus, Ohio); Joe Khalife (Irvine, California) |
| ABSTRACT | Processes and device configurations are provided for navigation using communications signal observables and using differential and non-differential frameworks. Communication signals, such as cellular communication signals may be used to obtain position estimates of a device such as a rover or unmanned aerial vehicle. Frameworks are provided for determination of position estimates with and without the use of a base station device. Processes can include use of position estimates to aid navigation. |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 18/548566 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/009 (20130101) G01S 5/0205 (20130101) Transmission H04B 7/2628 (20130101) Wireless Communication Networks H04W 4/024 (20180201) Original (OR) Class H04W 4/40 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240098887 | NAGARAJAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts); U.S. Government (Natick, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts); U.S. Government (Natick, Massachusetts) |
| INVENTOR(S) | Ramaswamy NAGARAJAN (Shrewsbury, Massachusetts); Jayant KUMAR (Westford, Massachusetts); Ravi MOSURKAL (Westford, Massachusetts); Siddhant IYER (Canton, Massachusetts); Claire LEPONT (Arlington, Massachusetts); Lian LI (North Chelmsford, Massachusetts) |
| ABSTRACT | A flexible circuit module is disclosed. The flexible circuit module includes a fabric member including a plurality of fibers having non-conductive elements, and conductive elements oriented through the plane of the fabric. Each conductive element includes a first fiber element strand and a first unterminated end opposite the first fiber element strand, and a second fiber element strand having second unterminated end opposite the second fiber element strand. The fabric member further includes a first side with the first fiber element strands extending therefrom and a second side with second fiber element strands extending therefrom. A first hook-and-loop busbar is conductively connected to the first fiber element strands and a second hook-and-loop busbar is conductively connected to the second fiber element strands. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/194589 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0201 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/189 (20130101) H05K 1/0263 (20130101) Original (OR) Class H05K 3/32 (20130101) H05K 2201/10272 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240099036 | LEE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Somin Eunice LEE (Ann Arbor, Michigan); Young Geun PARK (Ann Arbor, Michigan) |
| ABSTRACT | Plasmonic nanostructures function as an antenna-reactor nanostructure to focus and convert light into thermal/chemical energy, and thus have significant potential for sustainable solar water disinfection. However, the insufficient energy harvesting efficiency resulting from inconsistent nano-features linked with arrangement and scaling is a persistent challenge. An integrated optofluidic fabrication method is presented to produce a high density integrative plasmonic dimer array to enhance solar water disinfection. The plasmonic dimer array is constructed by a combined fabrication of self-assembly monolayer method and block-co-polymer lithography approaches. This combination leads to a two-dimensional hexagonal array of dimer structures consisting of 1.3 nm nanogap. The uniformity and high density of the nanogaps in the plasmonic dimer array allows strong light focusing and a rapid and highly efficient harvesting of photothermal energy at visible and near-infrared region. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/368711 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/14 (20130101) C02F 2303/04 (20130101) C02F 2305/08 (20130101) Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) G02B 2207/101 (20130101) Organic electric solid-state devices H10K 30/35 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20240090531 | MACQUEEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tender Food, Inc. (Somerville, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Luke MACQUEEN (Cambridge, Massachusetts); John Andrew GETSY, IV (Boston, Massachusetts); Elizabeth EISENACH (Boston, Massachusetts); Jade Elizabeth ZHU (Cambridge, Massachusetts); Richard COLWELL (Somerville, Massachusetts); Gemma COTTON (Allston, Massachusetts); Matthew SKINNER (Somerville, Massachusetts) |
| ABSTRACT | Embodiments described herein relate to blended meat substitute products and methods of producing the same. In some aspects, a method of producing a meat substitute product can include providing a plant based scaffolding with a carrier material, the carrier material including animal cells, adding a gelation agent to at least one of the plant-based scaffolding, and incubating the carrier material and the plant-based scaffolding in a controlled environment to produce a meat substitute product. In some embodiments, the animal cells can include at least one of skeletal muscle cells, fat cells, connective tissue cells, or skin cells. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/352348 |
| CURRENT CPC | Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/227 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240090810 | Woody et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania); UPMC (PITTSBURGH, Pennsylvania); NORTHEASTERN UNIVERSITY (BOSTON, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania); UPMC (PITTSBURGH, Pennsylvania); NORTHEASTERN UNIVERSITY (BOSTON, Massachusetts) |
| INVENTOR(S) | Mary L. Woody (Pittsburgh, Pennsylvania); Murat Akcakaya (Pittsburgh, Pennsylvania); Sarah Ostadabbas (Watertown, Massachusetts); Rebecca Price (Pittsburgh, Pennsylvania); Xiaofei Huang (Lynnfield, Massachusetts); Richard T. Gall (Pittsburgh, Pennsylvania); Anna Wears (Pittsburgh, Pennsylvania); Nastasia O. McDonald (Pittsburgh, Pennsylvania); Jennifer Mak (Pittsburgh, Pennsylvania) |
| ABSTRACT | A neurofeedback system includes an EEG apparatus, a presentation apparatus and a controller. The controller is configured to: (i) cause the presentation apparatus to display an overlaid image to the user that comprises a first image flickering at a first frequency and a second image flickering at a second frequency different than the first frequency, the first image being an affective distractor stimulus image and the second image being a task-relevant stimulus image, (ii) receive from the EEG apparatus a number of first steady-state visual evoked potential (SSVEP) signals generated in response the first image of the overlaid image and a number of second SSVEP signals generated in response the second image of the overlaid image, and (iii) calculate feedback indicative of how much attention of the was user allocated to the task-relevant stimulus image versus how much attention of the user was allocated to the affective distractor stimulus image. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/469782 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/168 (20130101) Original (OR) Class A61B 5/378 (20210101) A61B 5/6803 (20130101) A61B 5/7257 (20130101) A61B 90/36 (20160201) A61B 2090/365 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240090814 | VITALE, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Flavia VITALE, III (Wilmington, Delaware); Nicolette DRISCOLL (Somerville, Massachusetts); Nicholas V. APOLLO (San Diego, California); Brian LITT (Bala Cynwyd, Pennsylvania) |
| ABSTRACT | Provided are are conformable conductors and electrode arrays and related methods of their manufacture and use. The disclosed structures can be implanted into or placed outside of the body of a subject to record biosignals and/or to deliver electrical stimulation, in addition to other, non-biological applications for electrical and/or chemical sensing and stimulation. One can form a pattern an absorbent material (e.g., with a laser cutter), which is later infused with a conductive ink that can include, e.g., MXene materials, reduced graphene oxide (rGO), graphene/graphite, gold, platinum, or other metallic nanoparticles, carbon nanotubes, conductive polymers, or other conductive ink materials. The resulting electrode arrays can be compatible with magnetic resonance imaging (MRI or fMRI) and transcranial magnetic stimulation (TMS) modalities, and the disclosed process can rapidly produce electrodes at high yield. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/767709 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/27 (20210101) Original (OR) Class A61B 5/268 (20210101) A61B 5/6846 (20130101) A61B 2562/125 (20130101) A61B 2562/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091165 | Steinmetz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California); Jonathan Pokorski (San Diego, California) |
| ABSTRACT | A melt processed viral nanoparticle construct for delivery of virus or virus-like particles to a site of interest includes a degradable polymer matrix and a plurality of virus or virus-like particles encapsulated within the degradable polymer matrix. The nanoparticle construct upon administration to the site of interest providing a sustained release of the virus or virus-like particles and/or nanoparticles upon degradation of the polymer matrix. |
| FILED | Tuesday, May 23, 2023 |
| APPL NO | 18/200828 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) A61K 9/5153 (20130101) A61K 9/5184 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/18071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091732 | Elias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rachel Cassidy Elias (Ann Arbor, Michigan); Suljo Linic (Ann Arbor, Michigan) |
| ABSTRACT | The disclosure relates to a photoreactor for performing photocatalytic reactions with a particulate photocatalyst loaded in the reactor. The photoreactor includes an internal wall having an outer surface and defining an interior volume, and a transparent external wall having an outer surface and an opposing inner surface. The internal and external walls are spaced apart so that they together define a reaction volume between the walls. The photoreactor further includes an external light transmission apparatus, such as a light source and/or a light guide, positioned around the external wall and being adapted to transmit light through the external and into the reaction volume. When a particulate photocatalyst loaded in the reaction volume is irradiated by external light transmission apparatus while a reactant is flowing through the reaction volume, a photocatalytic reaction can be performed to form a desired reaction product. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/370517 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/12 (20130101) Original (OR) Class B01J 19/0013 (20130101) B01J 2219/00058 (20130101) B01J 2219/0254 (20130101) B01J 2219/00711 (20130101) B01J 2219/0871 (20130101) B01J 2219/0875 (20130101) B01J 2219/0877 (20130101) B01J 2219/00934 (20130101) B01J 2219/00961 (20130101) B01J 2219/1923 (20130101) B01J 2219/1943 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091831 | Quigley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut); Nicole Neff (North Potomac, Maryland); Jack Rowbottom (Swansea, Massachusetts) |
| ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system comprising a plurality of wells are provided herein. In some embodiments, the method comprises obtaining a concentration of a greenhouse gas measured a distance above a surface of a region comprising the plurality of wells; determining whether the measure of the concentration of the greenhouse gas is greater than a first threshold; and in response to determining that the measure of the concentration of the greenhouse gas is greater than the first threshold, increasing a flow rate of landfill gas being extracted from at least one well of the plurality of wells. |
| FILED | Wednesday, November 22, 2023 |
| APPL NO | 18/517492 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class B09B 2101/25 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092119 | SORGER |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Volker J. SORGER (Alexandria, Virginia) |
| ABSTRACT | A material transfer system transfers 2-dimensional (2D) material to or from a substrate. The system comprises a transfer apparatus having a transfer material holder for retaining a transfer material, and a stamping apparatus having an intermediate portion with a longitudinal axis and a distal end portion. The distal end portion has a proximal section, middle section and distal section forming a distal end face. The middle section is curved with respect to the longitudinal axis to form a stamper contact surface at the middle section. The stamper contact is surface configured to contact the transfer material. |
| FILED | Thursday, April 27, 2023 |
| APPL NO | 18/140454 |
| CURRENT CPC | Producing Decorative Effects; Mosaics; Tarsia Work; Paperhanging B44C 1/1733 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092708 | Koide et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kazunori Koide (Pittsburgh, Pennsylvania); James Proviano Burrows (West Homestead, Pennsylvania) |
| ABSTRACT | A method of reducing an aromatic ring or a cyclic, allylic ether in a compound includes preparing a reaction mixture including a compound including an aromatic moiety or a cyclic, allylic ether moiety, an alkali metal, and either ethylenediamine, diethylenetriamine, triethylenetetramine, or a combination thereof, in an ether solvent; and reacting the reaction mixture at from −20° C. to 30° C. for a time sufficient to reduce a double bond in the aromatic moiety to a single bond or to reduce the cyclic, allylic ether moiety. |
| FILED | Tuesday, November 28, 2023 |
| APPL NO | 18/521250 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 31/00 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 41/20 (20130101) C07C 51/347 (20130101) C07C 67/30 (20130101) C07C 2523/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092710 | WACHSMAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric D. WACHSMAN (Fulton, Maryland); Dongxia LIU (Clarksville, Maryland); Mann SAKBODIN (Bangkok, Thailand) |
| ABSTRACT | In a first stage of a methane conversion system, at least some methane (CH4) in an input gas flow stream can be converted into C2 hydrocarbons, hydrogen gas (H2), and aromatics to provide a first processed stream. The conversion can be direct non-oxidative methane conversion (DNMC). At least some of the aromatics can be removed from the first processed stream to provide a second processed stream. In a second stage of the methane conversion system, at least some of the H2 can be removed from the second processed stream to provide a recycle stream. The recycle stream can be returned to the first stage of the methane conversion system for further conversion of methane and removal of aromatics and H2 products. |
| FILED | Wednesday, November 22, 2023 |
| APPL NO | 18/517843 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 10/00 (20130101) B01J 19/0053 (20130101) B01J 19/1893 (20130101) B01J 21/08 (20130101) B01J 23/745 (20130101) Acyclic or Carbocyclic Compounds C07C 2/84 (20130101) Original (OR) Class C07C 2521/08 (20130101) C07C 2523/745 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092833 | Deming et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy J. Deming (Los Angeles, California); Eric G. Gharakhanian (Los Angeles, California) |
| ABSTRACT | Methodology was developed for transformation of methionine residues into homocysteine derivatives. Methionine residues can undergo alkylation reactions at low pH to yield sulfonium ions, which can then be selectively demethylated to give alkyl homocysteine residues. This process tolerates many functional groups. |
| FILED | Thursday, August 17, 2023 |
| APPL NO | 18/235184 |
| CURRENT CPC | Peptides C07K 1/006 (20130101) C07K 1/107 (20130101) C07K 1/113 (20130101) C07K 1/1133 (20130101) C07K 7/06 (20130101) Original (OR) Class C07K 14/001 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) C08G 69/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092965 | Azoulay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jason D. Azoulay (Atlanta, Georgia); Lifeng Huang (Hattiesburg, Mississippi); Alexander E. London (Hattiesburg, Mississippi); Naresh Eedugurala (Hattiesburg, Mississippi) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN MISSISSIPPI (HATTIESBURG, Mississippi) |
| INVENTOR(S) | Jason D. Azoulay (Atlanta, Georgia); Lifeng Huang (Hattiesburg, Mississippi); Alexander E. London (Hattiesburg, Mississippi); Naresh Eedugurala (Hattiesburg, Mississippi) |
| ABSTRACT | The invention provides for polymer structures and their preparation and resulting novel functionalities including open-shell character and high intrinsic conductivity with wide-range tenability. Electrical conductivity can be further modulated by introducing or blending with materials, fillers, dopants, and/or additives. The materials or resultant composites of the invention can be processed by various techniques into different forms to realize multiple applications. |
| FILED | Tuesday, August 08, 2023 |
| APPL NO | 18/366977 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/126 (20130101) Original (OR) Class C08G 2261/18 (20130101) C08G 2261/122 (20130101) C08G 2261/148 (20130101) C08G 2261/414 (20130101) C08G 2261/514 (20130101) C08G 2261/1646 (20130101) C08G 2261/3223 (20130101) C08G 2261/3225 (20130101) C08G 2261/3241 (20130101) C08G 2261/3243 (20130101) C08G 2261/3246 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2365/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/041 (20170501) C08K 2201/001 (20130101) C08K 2201/011 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/16 (20130101) H01B 1/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093065 | Shan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wanliang Shan (Jameville, New York); Guangchao Wan (College Station, Texas) |
| ASSIGNEE(S) | Syracuse University (Syracuse, New York) |
| INVENTOR(S) | Wanliang Shan (Jameville, New York); Guangchao Wan (College Station, Texas) |
| ABSTRACT | An approach to achieve highly tunable adhesion using low pressure by inducing sidewall buckling in soft hollow pillars (SHPs). Dry adhesion of these SHPs can be changed by two orders of magnitude (up to 145×) using low activating pressure (˜−10 kPa or ˜20 kPa). Negative pressure triggers sidewall buckling while positive pressure induces sidewall bulging, both of which can significantly change stress distribution at the bottom surface to facilitate crack initiation and reduce adhesion therein. A single SHP can be activated by a micropump to manipulate various lightweight objects with different curvature and surface texture. An array of SHPs can realize selective pick-and-place of an array of objects. Minor modifications to the SHPs in terms of geometry and material (with or without cap, circular or noncircular cross section) can further enhance the adhesion tuning performance of these SHPs. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/243919 |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/38 (20180101) Original (OR) Class C09J 2301/31 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093139 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiong Yu (Beachwood, Ohio); Xijin Zhang (Cleveland, Ohio) |
| ABSTRACT | A mycelium composite material includes a fungi generated mycelium fiber matrix and a biofiller (organic or inorganic or combined) dispersed within the matrix. The biofiller provides a structural element and nutrition source for the fungi and the mycelium fibers bind the biofiller. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/467960 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) Original (OR) Class General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/78 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093160 | Steinmetz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California); Hema Masarapu (Cleveland, Ohio); He Hu (Cleveland, Ohio) |
| ABSTRACT | A method of targeting cancer tissue in a subject includes administering to the subject a plurality of functionalized Tymovirus virus or virus-like particles loaded with or conjugated to an imaging agent, a therapeutic agent or a targeting agent. |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/239463 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/136 (20130101) A61K 47/55 (20170801) A61K 47/546 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093208 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ting Lu (Savoy, Illinois); Wentao Kong (Champaign, Illinois) |
| ABSTRACT | Provided herein are systems that provide a genetic program to control bacterial life cycle and function execution, thereby conferring programmable microbial transition between planktonic and biofilm states and facilitating the development of cellular functions across physiological domains. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/463837 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/22 (20130101) C12N 9/0071 (20130101) C12N 9/2417 (20130101) C12N 9/2471 (20130101) C12N 15/11 (20130101) C12N 15/74 (20130101) C12N 15/635 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2509/00 (20130101) C12N 2800/80 (20130101) C12N 2800/101 (20130101) C12N 2830/002 (20130101) C12N 2830/005 (20130101) Enzymes C12Y 114/14 (20130101) C12Y 302/01001 (20130101) C12Y 302/01023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093217 | Bailey-Serres et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julia Bailey-Serres (Orange, California); Alexander T. Borowsky (Riverside, California); Mauricio Reynoso (La Plata, Argentina) |
| ABSTRACT | The present disclosure provides a list of genes, and the proteins encoded by these genes, that modulate and/or participate in the synthesis of the biopolymer suberin. The genes described here are useful in methods for producing genetically modified plants or breeding plants with increased or decreased suberin. Such plants can contain modified, mutated, or engineered candidate peptides; or have disrupted or enhanced expression using methods such as clustered regularly-interspaced short palindromic repeats (CRISPR)/CRISPR associated (Cas) nuclease, an antisense nucleic acid, a zinc finger nuclease (ZFN), or a transcription activator-like effector (TALE) nuclease. Increased suberin has a positive influence on response to plant water stress and pathogen protection, and a long-lasting role as a carbon sink in soil; and decreased suberin encourages symbioses and nutrient uptake. |
| FILED | Monday, August 14, 2023 |
| APPL NO | 18/449242 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8243 (20130101) Original (OR) Class C12N 15/8273 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093218 | Hannapel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); Indian Institute of Science Education and Research (IISER) (Pune, Maharashtra, India) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David J. Hannapel (Ames, Iowa); Anjan K. Banerjee (Pune, India) |
| ABSTRACT | The present invention relates to a nucleic acid construct. The nucleic acid construct includes a nucleic acid molecule configured to silence or reduce the expression of StBEL11 and/or StBEL29 and variants thereof, a 5′ DNA promoter sequence, and a 3′ terminator sequence, where the first nucleic acid molecule, the promoter sequence, and the terminator sequence are operatively coupled to permit transcription of the first nucleic acid molecule. The present invention is also directed to vectors, host cells, transgenic plants, and transgenic plant seeds, as well as non-transgenic mutant plants, and methods for altering tuber yield in a plant. |
| FILED | Tuesday, August 15, 2023 |
| APPL NO | 18/449887 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8226 (20130101) C12N 15/8234 (20130101) C12N 15/8261 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093246 | Redding et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Redding (Tempe, Arizona); Andrey Kanygin (Phoenix, Arizona) |
| ABSTRACT | Provided herein, in some embodiments, are engineered cells and use of the same for increased hydrogen production. In particular, provided herein are genetically engineered cells comprising a polynucleotide encoding a fusion protein comprising a photosystem I (PSI) protein and a bacterial hydrogenase, as well as methods for producing such genetically engineered cells. Also provided herein are methods for increasing hydrogen (H2) production in cells. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/349764 |
| CURRENT CPC | Peptides C07K 14/405 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0067 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) Original (OR) Class Enzymes C12Y 112/07002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093263 | Abbas |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abdennour Abbas (St. Paul, Minnesota) |
| ABSTRACT | Methods that include combining a probe with a composition including a microorganism, wherein the probe includes a targeting portion that interacts with a phylogenetic surface marker (PSM) on the microorganism to at least partially coat the microorganism with the probe. |
| FILED | Wednesday, March 29, 2023 |
| APPL NO | 18/128048 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) C12Q 1/06 (20130101) Original (OR) Class C12Q 1/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/569 (20130101) G01N 33/56916 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093273 | KARTALOV et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emil P. KARTALOV (PASADENA, California); Aditya RAJAGOPAL (ORANGE, California); Axel SCHERER (BARNARD, Vermont) |
| ABSTRACT | This disclosure provides methods, systems, compositions, and kits for the multiplexed detection of a plurality of analytes in a sample. In some examples, this disclosure provides methods, systems, compositions, and kits wherein multiple analytes may be detected in a single sample volume by acquiring a cumulative measurement or measurements of at least one quantifiable component of a signal. In some cases, additional components of a signal, or additional signals (or components thereof) are also quantified. Each signal or component of a signal may be used to construct a coding scheme which can then be used to determine the presence or absence of any analyte. |
| FILED | Tuesday, November 21, 2023 |
| APPL NO | 18/516842 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6851 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 25/00 (20190201) G16B 25/20 (20190201) G16B 40/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093407 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Fang Liu (New York, New York); Xiaoyang Zhu (New York, New York); James Hone (New York, New York); Sang Hoon Chae (New York, New York) |
| ABSTRACT | Systems and methods for generating one or more single crystal monolayers from two-dimensional van der Waals crystals are disclosed herein. Example methods include providing a bulk material including a plurality of van der Waals crystal layers, and exfoliating one or more single crystal monolayers of van der Waals crystal from the bulk material by applying a flexible and flat metal tape to a surface of the bulk material. In certain embodiments, the one or more single crystal monolayers can be assembled into an artificial lattice. The present disclosure also provides techniques for manufacturing flexible and flat metal tape for generating one or more single crystal monolayers from two-dimensional van der Waals crystals. The present disclosure also provides compositions for creating a macroscopic artificial lattice. In certain embodiments, the composition can include two or more macroscopic single crystal monolayers adapted from a bulk van der Waals crystal, where the single crystal monolayers are configured for assembly into an artificial lattice based on one or more properties. |
| FILED | Wednesday, November 29, 2023 |
| APPL NO | 18/522460 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/02 (20130101) B32B 18/00 (20130101) B32B 37/18 (20130101) B32B 37/025 (20130101) B32B 43/006 (20130101) B32B 2315/02 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 41/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/16 (20130101) C23C 14/30 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/46 (20130101) C30B 29/68 (20130101) C30B 33/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093938 | PRASAD et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF NORTH TEXAS (Dallas, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vish PRASAD (Dallas, Texas); Guo-Xiang WANG (Akron, Ohio); Kuruvilla JOHN (Dallas, Texas); Huseyin BOSTANCI (Dallas, Texas); Hamid SADAT (Dallas, Texas); Laura ALMARA (Dallas, Texas) |
| ABSTRACT | A method of transporting a single gas or a gas mixture, pure or with impurities, through a pipeline, wherein the gas has a critical pressure, a critical temperature, a cricondenbar, and/or a cricondentherm and wherein the gas flows above the critical pressure, the critical temperature, the cricondenbar, the cricondentherm, and/or the anomalous state from the inlet to exit of the pipeline. |
| FILED | Wednesday, August 02, 2023 |
| APPL NO | 18/364386 |
| CURRENT CPC | Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 3/0209 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094106 | MAO et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leidong MAO (Watkinsville, Georgia); Yang LIU (Albany, California) |
| ABSTRACT | The present application provides devices, kits, and methods for label-free separation of cells and/or other small particles with high resolution and throughput. Devices, kits, and methods of the present disclosure include a focusing stage for inertial based focusing of cells/particles in a sample followed by ferrohydrodynamic, size-based separation in a separation stage. These devices, kits and methods provide the ability to separate and enrich target cells/particles from a sample with high resolution and efficiency. |
| FILED | Thursday, February 03, 2022 |
| APPL NO | 18/274507 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0272 (20130101) Original (OR) Class G01N 2015/016 (20240101) G01N 2015/0288 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094517 | CUNNINGHAM et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian T. CUNNINGHAM (Champaign, Illinois); Nantao LI (Champaign, Illinois); Taylor D. CANADY (Champaign, Illinois); Qinglan HUANG (Santa Clara, California); Xing WANG (Champaign, Illinois) |
| ABSTRACT | Disclosed herein are methods and systems that use a photonic crystal (PC) for interference scattering microscopy. Incident light is directed onto a surface of the PC and couples into a photonic crystal guided resonance (PCGR) mode of the PC such that less than 1% of the incident light is transmitted through the PC as transmitted light. One or more particles adjacent to the surface of the PC scatter a portion of the light coupled into the PCGR mode as scattered light. An image comprising a pattern of constructive and destructive interference between the transmitted light and the scattered light is formed, and an image sensor may capture one or more image frames of the image Imaging processing of the one or more image frames can be used to identify at least one scattering center corresponding to at least one particle of the one or more particles. |
| FILED | Thursday, February 03, 2022 |
| APPL NO | 18/263749 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0056 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095381 | SADEH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Norman SADEH (Pittsburgh, Pennsylvania); Bin LIU (Pittsburgh, Pennsylvania); Anupam DAS (Pittsburgh, Pennsylvania); Martin DEGELING (Pittsburgh, Pennsylvania); Florian SCHAUB (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system comprises a IoT resource and a computing device of a user. The computing device comprises a processor that executes a personal privacy app that receives data about the IoT resource and communicates a preference setting for the user with respect to the IoT device. The preference setting is based on the data received about the IoT resource. |
| FILED | Tuesday, August 29, 2023 |
| APPL NO | 18/239267 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/604 (20130101) Original (OR) Class G06F 21/629 (20130101) G06F 21/6245 (20130101) Computer Systems Based on Specific Computational Models G06N 7/00 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/101 (20130101) H04L 63/102 (20130101) H04L 67/12 (20130101) H04L 67/306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095528 | Seo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jae-sun Seo (Tempe, Arizona); Jian Meng (Tempe, Arizona); Li Yang (Tempe, Arizona); Deliang Fan (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jae-sun Seo (Tempe, Arizona); Jian Meng (Tempe, Arizona); Li Yang (Tempe, Arizona); Deliang Fan (Tempe, Arizona) |
| ABSTRACT | A method for increasing the temperature-resiliency of a neural network, the method comprising loading a neural network model into a resistive nonvolatile in-memory-computing chip, training the deep neural network model using a progressive knowledge distillation algorithm as a function of a teacher model, the algorithm comprising injecting, using a clean model as the teacher model, low-temperature noise values into a student model and changing, now using the student model as the teacher model, the low-temperature noises to high-temperature noises, and training the deep neural network model using a batch normalization adaptation algorithm, wherein the batch normalization adaptation algorithm includes training a plurality of batch normalization parameters with respect to a plurality of thermal variations. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/463778 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/0495 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095769 | Braun et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | James Edward Braun (West Lafayette, Indiana); Julia Michelle Rayz (West Lafayette, Indiana); Panagiota Karava (West Lafayette, Indiana); Ilias Bilionis (West Lafayette, Indiana); Hemanth Devarapalli (West Lafayette, Indiana); Huijeong Kim (West Lafayette, Indiana); Sang Woo Ham (Berkeley, California); Vanessa Kwarteng (Bloomfield, New Jersey); Marlen Promann (West Lafayette, Indiana) |
| ABSTRACT | A system may provide an eco-feedback and gaming platform for home energy management. The system may generate daily energy scores for a plurality of households. The system may prepare a community energy conservation game in which community conservation goals and participation thresholds are generated. The system may execute the game by receiving time series date from each of the households and rewards the households for participating in achieving the community goal. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/244187 |
| CURRENT CPC | Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/80 (20140902) A63F 13/798 (20140902) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0209 (20130101) Original (OR) Class G06Q 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095923 | Kandlikar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bired Imaging, Inc. (Rochester, New York) |
| ASSIGNEE(S) | Bired Imaging, Inc. (Rochester, New York) |
| INVENTOR(S) | Satish G. Kandlikar (Rochester, New York); Donnette Dabydeen (Pittsford, New York); Lori Medeiros (Pittsford, New York); Pradyumna Phatak (Pittsford, New York); Jose Luis Gonzalez Hernandez (Rochester, New York); Alyssa Owens (East Rochester, New York) |
| ABSTRACT | Processes and techniques are disclosed to identify regions of suspected malignancy and their localization within a body part or organ. These methods rely on the analysis of infrared images to identify thermal abnormalities using image post-processing techniques, numerical modeling, iterative solutions methodology or a digital library. The methods utilize noninvasive, non-radiative and no contact infrared imaging that can be used for breast cancer screening for improved prognosis. |
| FILED | Tuesday, November 21, 2023 |
| APPL NO | 18/515883 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/015 (20130101) A61B 5/489 (20130101) A61B 5/4312 (20130101) Image Data Processing or Generation, in General G06T 7/0014 (20130101) Original (OR) Class G06T 7/30 (20170101) G06T 7/62 (20170101) G06T 17/00 (20130101) G06T 2207/10048 (20130101) G06T 2207/10088 (20130101) G06T 2207/10116 (20130101) G06T 2207/10132 (20130101) G06T 2207/20221 (20130101) G06T 2207/30068 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096034 | Adib et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Fadel Adib (Cambridge, Massachusetts); Tara Boroushaki (Cambridge, Massachusetts); Laura Noelle Dodds (Cambridge, Massachusetts); Aline Eid (Ann Arbor, Michigan); Maisy Lilian Lam (Cambridge, Massachusetts) |
| ABSTRACT | According to one aspect of the disclosure, a mobile augmented reality (AR) system can include: a receiver configured to receive radio frequency (RF) signals from one or more items located within an environment; a tracking module configured to generate tracking data responsive to a location of the system within the environment over time; a display device; and one or more processors configured to determine a location of at least one of the one or more items within the environment using the received RF signals and the tracking data, and generate a visual representation of the location of the at least one item for display on the display device. |
| FILED | Thursday, July 20, 2023 |
| APPL NO | 18/355600 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/06 (20130101) Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096047 | Farhadi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Mohammad Farhadi (Tempe, Arizona); Yezhou Yang (Scottsdale, Arizona); Rahul Santhosh Kumar Varma (Tempe, Arizona) |
| ABSTRACT | Based on traffic images characteristics, a general pre-processing system and method reduces input size of neural network object recognition models to focus on necessary regions. The system includes a light neural network (binary or low precision; based on configuration) to detect target regions for further processing and applies a deeper model to those specific regions. The present disclosure provides experimentation results on various types of methods, such as conventional convolutional neural networks, transformers, and adaptive models, to show the scalability of the system. |
| FILED | Friday, September 01, 2023 |
| APPL NO | 18/460053 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/25 (20220101) Original (OR) Class G06V 10/82 (20220101) G06V 20/54 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097228 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yu Wang (Cleveland, Ohio); Chris Yingchun Yuan (Solon, Ohio) |
| ABSTRACT | A method of relithiating a spent cathode material from a spent lithium ion battery includes mixing the spent lithium cathode material with a particulate lithium source and heating the mixture to a temperature effective to sinter the mixture and relithiate the spent lithium cathode material. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/467820 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/049 (20130101) H01M 4/0471 (20130101) H01M 10/54 (20130101) Original (OR) Class H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097326 | Towfiq et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | i5 Technologies, Inc. (North Logan, Utah); Utah State University (Logan, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Asaduzzaman Towfiq (North Logan, Utah); Bedri A. Cetiner (North Logan, Utah) |
| ABSTRACT | Among other things, a reconfigurable antenna array (RAA) includes individual pattern reconfigurable antennas (PRA). Each of the PRAs has (a) an antenna, (b) components controllable to generate and effect any of two or more modes of the PRA, the modes having respectively different steered radiation patterns, and (c) inputs to receive drive signals for the antenna and control signals for the controllable components. Control circuitry has outputs coupled to the inputs of the PRAs to drive the antennas of the PRAs to form an array beam having an array peak in a particular direction and at the same time to deliver control signals for the controllable components to effect a selected mode of each of the PRAs for which the steered radiation pattern has a peak in the particular direction of the array beam and has one or more nulls in the directions of one or more of the side-lobes of the array beam. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/232170 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/2617 (20130101) Original (OR) Class H01Q 9/0442 (20130101) H01Q 19/005 (20130101) H01Q 21/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097601 | FORREST et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Stephen R. FORREST (Ann Arbor, Michigan); Tobias BURGER (Ann Arbor, Michigan); Andrej LENERT (Ann Arbor, Michigan); Bosun ROY-LAYINDE (Ann Arbor, Michigan); Jinun LIM (Ann Arbor, Michigan) |
| ABSTRACT | A tandem photovoltaic (PV) may include III-V semiconductors, silicon, a cathode electrode, an anode electrode, and a gold-to-gold metal bridge electrode. The semiconductors include p-typed and n-typed regions. To form a tandem PV structure, bottom and top PV cells can be independently fabricated. The bottom and the top PV cells are electrically connected by the gold-to-gold metal bridge interconnection, which is positioned between the bottom and the top PV cells. The metal bridge may be formed by cold-welding compression technique. This structure is compatible to the development of tandem PVs as well as thermophotovoltaic (TPV) cells. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/369956 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0725 (20130101) H01L 31/0735 (20130101) H01L 31/1844 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240098451 | Kassas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zak Kassas (Columbus, Ohio); Joe Khalife (Irvine, California) |
| ABSTRACT | Processes and device configurations are provided for navigation using communications signal observables and using differential and non-differential frameworks. Communication signals, such as cellular communication signals may be used to obtain position estimates of a device such as a rover or unmanned aerial vehicle. Frameworks are provided for determination of position estimates with and without the use of a base station device. Processes can include use of position estimates to aid navigation. |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 18/548566 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/009 (20130101) G01S 5/0205 (20130101) Transmission H04B 7/2628 (20130101) Wireless Communication Networks H04W 4/024 (20180201) Original (OR) Class H04W 4/40 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240099036 | LEE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Somin Eunice LEE (Ann Arbor, Michigan); Young Geun PARK (Ann Arbor, Michigan) |
| ABSTRACT | Plasmonic nanostructures function as an antenna-reactor nanostructure to focus and convert light into thermal/chemical energy, and thus have significant potential for sustainable solar water disinfection. However, the insufficient energy harvesting efficiency resulting from inconsistent nano-features linked with arrangement and scaling is a persistent challenge. An integrated optofluidic fabrication method is presented to produce a high density integrative plasmonic dimer array to enhance solar water disinfection. The plasmonic dimer array is constructed by a combined fabrication of self-assembly monolayer method and block-co-polymer lithography approaches. This combination leads to a two-dimensional hexagonal array of dimer structures consisting of 1.3 nm nanogap. The uniformity and high density of the nanogaps in the plasmonic dimer array allows strong light focusing and a rapid and highly efficient harvesting of photothermal energy at visible and near-infrared region. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/368711 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/14 (20130101) C02F 2303/04 (20130101) C02F 2305/08 (20130101) Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) G02B 2207/101 (20130101) Organic electric solid-state devices H10K 30/35 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240091740 | Ellebracht et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nathan C. Ellebracht (Oakland, California); Sarah E. Baker (Dublin, California); Eric B. Duoss (Dublin, California); Simon Hoching Pang (Fremont, California); Joshuah K. Stolaroff (Oakland, California) |
| ABSTRACT | A method of forming a product for separating gases includes forming a three-dimensional ceramic support, heating the three-dimensional ceramic support at a temperature for an effective duration of time to result in the conductive ceramic material having a plurality of intra-material pores, and incorporating a sorbent additive into the intra-material pores of the conductive ceramic material. Moreover, the three-dimensional ceramic support includes an electrically conductive ceramic material configured for joule heating. |
| FILED | Tuesday, November 28, 2023 |
| APPL NO | 18/521945 |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/82 (20130101) B01D 53/96 (20130101) B01D 2253/202 (20130101) B01D 2257/504 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/0251 (20130101) B01J 20/262 (20130101) Original (OR) Class B01J 20/3007 (20130101) B01J 20/3078 (20130101) B01J 20/3204 (20130101) B01J 20/3272 (20130101) B01J 20/3293 (20130101) B01J 20/3425 (20130101) B01J 20/3441 (20130101) B01J 20/28011 (20130101) B01J 20/28023 (20130101) B01J 20/28059 (20130101) B01J 20/28061 (20130101) B01J 20/28085 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/50 (20170801) C01B 2210/0007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091808 | Schwartz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Johanna Jesse Schwartz (Livermore, California); Marissa Wood (Oakland, California); Jianchao Ye (Tracy, California); Adam W. Jaycox (Livermore, California); Xiaoting Zhong (Livermore, California) |
| ABSTRACT | Screening for screening a material includes: providing active mixing direct-ink-writing of the material, providing in situ characterization substrates or probes that receive the material, and providing active learning planning for screening the material. The providing active mixing direct-ink-writing of the material prints five to ten films. The providing in situ characterization substrates or probes includes printing five to ten films on the substrates or probes with a first set of constituents. The providing active learning planning for screening the material includes providing machine learning that takes the first set of constituents and uses the first set of constituents to dictate a next batch of films to achieve improved additional sets of constituents. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/932723 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) Original (OR) Class B05D 1/26 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/40 (20130101) H01M 10/0562 (20130101) H01M 10/0565 (20130101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092192 | Sujan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vivek A. Sujan (Oak Ridge, Tennessee); David E. Smith (Oak Ridge, Tennessee); Richard W. Davies (Oak Ridge, Tennessee) |
| ABSTRACT | A vehicle includes a traction inverter and an electric motor operable to provide motive power for the vehicle based on electrical power received wirelessly from a modular power system. |
| FILED | Thursday, September 14, 2023 |
| APPL NO | 18/368037 |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/66 (20190201) B60L 53/12 (20190201) Original (OR) Class B60L 2210/30 (20130101) B60L 2210/42 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092225 | Sujan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vivek Sujan (Oak Ridge, Tennessee) |
| ABSTRACT | An improved power-split control system for managing a load profile of a fuel cell in a fuel cell electric vehicle (FCEV) is provided. The power-split control system is operable to actively manage the power demand between the fuel cell and the battery of a FCEV to optimize the operational life of the fuel cell. The power-split control system can use information gathered solely from historical drive cycle data or from historical drive cycle data combined with look-ahead eHorizon data. The power-split control system meets a power demand by operating the powertrain in either a battery charge sustaining mode or a battery charge depletion mode. The power-split control system is also configured to control the power distribution (to the electric motor) from the fuel cell and the battery in a manner that minimizes the degradation of the fuel cell. |
| FILED | Tuesday, September 12, 2023 |
| APPL NO | 18/367054 |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 3/0053 (20130101) B60L 50/75 (20190201) B60L 58/13 (20190201) B60L 58/16 (20190201) B60L 58/40 (20190201) Original (OR) Class Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 20/13 (20160101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092649 | Villalon, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Phoenix Tailings, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | Phoenix Tailings, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Thomas Anthony Villalon, Jr. (Boston, Massachusetts); Henry Chase Hutcheson (Malden, Massachusetts) |
| ABSTRACT | The present disclosure is related to systems and methods for solid-phase reactions. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/463992 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/18 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 1/06 (20130101) Original (OR) Class C01G 3/05 (20130101) C01G 9/04 (20130101) C01G 49/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092713 | Ren |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | E2H2NANO, LLC. (Buffalo, New York) |
| ASSIGNEE(S) | E2H2NANO, LLC. (Buffalo, New York) |
| INVENTOR(S) | Shoujie Ren (Buffalo, New York) |
| ABSTRACT | Various aspects of an ion-gated nanochannel catalytic membrane reactor, disclosed herein. The ion-gated nanochannel catalytic membrane reactor includes a reaction unit comprising at least a plurality of reactants that react to produce one or more permeates at least due to activation by a catalyst. The membrane reactor further includes a separation unit including an ion-gated nanochannel membrane supported on a hollow fiber support. The polar permeates from the one or more permeates pass through the ion-gated nanochannel membrane and are separated in-situ. Multiple methods/processes using the ion-gated nanochannel catalytic membrane reactor for chemicals and fuels production are included. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/370643 |
| CURRENT CPC | Ammonia; Cyanogen; Compounds Thereof C01C 1/0411 (20130101) C01C 1/0417 (20130101) C01C 1/0458 (20130101) Acyclic or Carbocyclic Compounds C07C 29/74 (20130101) C07C 29/152 (20130101) Original (OR) Class C07C 29/153 (20130101) C07C 29/1512 (20130101) C07C 68/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092715 | Savara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aditya Savara (Oak Ridge, Tennessee); Bo Chen (Oak Ridge, Tennessee); Michelle K. Kidder (Oak Ridge, Tennessee) |
| ABSTRACT | A method of ethanol conversion to higher carbon compounds is provided. The method includes feeding a reactant to a reactor, the reactant including ethanol. The reactant may further include water in the form of steam. The reactant is introduced to a perovskite catalyst in the reactor. The perovskite catalyst promotes the formation of the higher carbon compounds from ethanol, and may be in the form of a powder or thin film. The perovskite catalyst has the formula ABO3, wherein A is one or more selected from a group consisting of La and Sr, and wherein B is one or more selected from a group consisting of Mn, Ca, Fe, and Co. The perovskite catalyst particularly may be La0.7Sr0.3MnO3. The obtained higher carbon compounds may include at least one of acetone and crotonaldehyde. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/368634 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/002 (20130101) B01J 23/02 (20130101) B01J 23/10 (20130101) Acyclic or Carbocyclic Compounds C07C 45/29 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093169 | HUMMEL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Niklas F. C. HUMMEL (San Francisco, California); Patrick M. SHIH (Berkeley, California) |
| ABSTRACT | The present invention provides for a synthetic transcription factor (TF) comprising (a) a DNA-binding domain of a transcription factor linked to (b) an effector domain, and (c) optionanlly a nuclear localization sequence (NLS). The present invention provides for a nucleic acid encoding an effector domain of the present invention. The DNA-binding domain can be a deactivated RNA-guided nuclease variant of Cas9 (dCas9). |
| FILED | Tuesday, April 11, 2023 |
| APPL NO | 18/298942 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/96 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093245 | Eiben et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Christopher B. Eiben (Berkeley, California); Jay D. Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a method for producing hydrogen peroxide comprising: (a) contacting a methanol with a methanol oxidase bound with a flavin adenine dinucleotide (FAD) cofactor, such that the methanol is oxidized into a formaldehyde and the FAD cofactor is reduced into FADH2; (b) contacting the formaldehyde with the methanol oxidase or a formate oxidase bound with a FAD cofactor, such that the formaldehyde is oxidized into a formate and the FAD is reduced into FADH2; and (c) contacting oxygen with one or more of the FADH2 to produce hydrogen peroxide and oxidize FADH2 into FAD. The present invention also provides for a fusion protein comprising any two or all of methanol oxidase, formate oxidase, and formaldehyde dismutase. |
| FILED | Monday, April 11, 2022 |
| APPL NO | 17/717141 |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0065 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) Original (OR) Class Enzymes C12Y 101/03013 (20130101) C12Y 102/03001 (20130101) C12Y 102/99004 (20130101) C12Y 111/01021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093352 | ROBERTS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Elwyn ROBERTS (Lugoff, Panama); Jonathan WRIGHT (Västerås, Sweden); Benjamin R. MAIER (Pittsburgh, Pennsylvania); Jorie WALTERS (Columbia, South Carolina); Denise ADORNO-LOPES (Västerås, Sweden); Kathryn E. METZGER (Columbia, South Carolina) |
| ABSTRACT | Nuclear fuel rods are disclosed. The nuclear fuel rods include a substrate and a chromium alloy coating layer applied to the substrate. The chromium alloy coating layer comprises chromium (Cr); a element or compound selected from the group consisting of yttrium (Y), lanthanum (La), thorium (Th), zirconium (Zr), titanium (Ti), hafnium (I-lf), molybdenum (Mo), tungsten (W), vanadium (V), rhenium (Re), ruthenium (Ru), cobalt (Co), aluminum (Al), carbides, borides, intermetallics, and combinations thereof; and interstitial elements up to 1500 ppm, wherein carbon (C), oxygen (O), and nitrogen (N) are each 500 ppm or less. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 18/253982 |
| CURRENT CPC | Alloys C22C 28/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/14 (20130101) Original (OR) Class C23C 16/06 (20130101) C23C 28/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093407 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Fang Liu (New York, New York); Xiaoyang Zhu (New York, New York); James Hone (New York, New York); Sang Hoon Chae (New York, New York) |
| ABSTRACT | Systems and methods for generating one or more single crystal monolayers from two-dimensional van der Waals crystals are disclosed herein. Example methods include providing a bulk material including a plurality of van der Waals crystal layers, and exfoliating one or more single crystal monolayers of van der Waals crystal from the bulk material by applying a flexible and flat metal tape to a surface of the bulk material. In certain embodiments, the one or more single crystal monolayers can be assembled into an artificial lattice. The present disclosure also provides techniques for manufacturing flexible and flat metal tape for generating one or more single crystal monolayers from two-dimensional van der Waals crystals. The present disclosure also provides compositions for creating a macroscopic artificial lattice. In certain embodiments, the composition can include two or more macroscopic single crystal monolayers adapted from a bulk van der Waals crystal, where the single crystal monolayers are configured for assembly into an artificial lattice based on one or more properties. |
| FILED | Wednesday, November 29, 2023 |
| APPL NO | 18/522460 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/02 (20130101) B32B 18/00 (20130101) B32B 37/18 (20130101) B32B 37/025 (20130101) B32B 43/006 (20130101) B32B 2315/02 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 41/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/16 (20130101) C23C 14/30 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/46 (20130101) C30B 29/68 (20130101) C30B 33/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093856 | Narendran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Nadarajah Narendran (Clifton Park, New York); Akila Shan Udage (Troy, New York) |
| ABSTRACT | One embodiment provides a lens structure. The lens structure includes a backend. The backend includes a backend back surface and a backend front surface. The backend is configured to receive a luminous flux from a light source and to redirect the received luminous flux onto a lens. The redirected luminous flux is configured to increase a luminous efficacy. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 18/274225 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Functional Features or Details of Lighting Devices or Systems Thereof; Structural Combinations of Lighting Devices With Other Articles, Not Otherwise Provided for F21V 5/045 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted F21Y 2115/10 (20160801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093939 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongbin Ma (Columbia, Missouri); Ramy Abdelhady (Columbia, Missouri); Shahabeddin K. Mohammadian (Columbia, Missouri); Jeremy Spitzenberger (Columbia, Missouri); Xiaoqin Susan Liu (Columbia, Missouri) |
| ABSTRACT | An efficient heat pump ejector vacuum dryer system and associated method of use for drying items that includes a drying vessel having a condenser and having a first evaporator where the first evaporator has an input that is connected to an output of the first expansion valve, a first expansion valve connected in fluid communication between the condenser and the first evaporator, a second expansion valve connected between the condenser and the second evaporator, a compressor having an input connected to an output of the first evaporator, an ejector that receives a vapor stream from an output of the compressor and receives a vapor stream from the output of the second evaporator generates as an output a high-temperature vapor provided to a condenser of the drying vessel to dry the items and generate an output of moisture, and a water reservoir that accumulates water from the drying vessel. |
| FILED | Thursday, September 14, 2023 |
| APPL NO | 18/467310 |
| CURRENT CPC | Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 5/04 (20130101) F26B 23/004 (20130101) Original (OR) Class F26B 23/005 (20130101) F26B 2210/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093943 | Turney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph E. Turney (Amston, Connecticut); Robert H. Dold (Monson, Massachusetts); Kathryn L. Kirsch (East Haddam, Connecticut) |
| ABSTRACT | A heat exchanger having: front and aft ends; heat exchanger cores in an annular loop that define circumferential gaps between adjacent pairs of the cores, the cores, individually or as axially aligned sets, extend from the front to aft ends and have facing inlet sides and circumferentially facing outlet sides configured such that the inlet sides and the outlet sides from the adjacent pairs of the cores face into the same circumferential gaps; and core guide vanes disposed in the circumferential gaps, the core guide vanes have an aft portion that extends from the front end to the aft end of the heat exchanger, wherein: at the front end the heat exchanger, the core guide vanes are closer to the outlet side of the cores; and at the aft end the heat exchanger, the core guide vanes are closer to the inlet sides of the cores. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/947337 |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/10 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/213 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/05366 (20130101) Original (OR) Class F28D 21/00 (20130101) F28D 2021/0026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093952 | Turney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph E. Turney (Amston, Connecticut); Robert H. Dold (Monson, Massachusetts); Kathryn L. Kirsch (East Haddam, Connecticut); Matthew B. Kennedy (Vernon, Connecticut) |
| ABSTRACT | A heat exchanger having: an inlet header having inlet tubes stacked against the first side of the heat exchanger; an outlet header having outlet tubes stacked against the second side of the heat exchanger, first inlet and outlet tubes have a same length as each other, second inlet and outlet tubes have the same length as each other and are longer than the first inlet and outlet tubes, and third inlet and outlet tubes have a same length as each other and are longer than the second inlet and outlet tubes; core channels extend from the first side to the second side of the heat exchanger, the core channels connect the inlet tubes to the outlet tubes such that: the first inlet tube and third outlet tube are connected; the second inlet tube and second outlet tube are connected; and the third inlet tube and first outlet tube are connected. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/945135 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 9/22 (20130101) F28F 9/0221 (20130101) Original (OR) Class F28F 9/0268 (20130101) F28F 2250/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093989 | PREVISIC et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Re Vision Consulting, LLC (Sacramento, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mirko PREVISIC (Sacramento, California); Ravi CHALLA (Sacramento, California); Anantha KARTHIKEYAN (Sacramento, California) |
| ABSTRACT | A method and system for prediction of wave properties include collecting time-series data streams from one or more wave measurement devices and processing the data to identify data parameters to establish boundary conditions of a numerical model. The numerical model may be used to compute a predicted wave field of time-series data for a variety of wave properties at a target location. |
| FILED | Tuesday, November 14, 2023 |
| APPL NO | 18/389524 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 13/002 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/0206 (20130101) Electric Digital Data Processing G06F 30/28 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094063 | Sweeney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel C. Sweeney (Oak Ridge, Tennessee); Christian M. Petrie (Oak Ridge, Tennessee); Adrian M. Schrell (Oak Ridge, Tennessee) |
| ABSTRACT | A system and method for determining an object characteristic from a timed sequence of measured characteristics wherein the object characteristic is determined based on a comparison of a current measured characteristic against a variable reference characteristic. The variable reference characteristic is selected by iterating through the timed sequenced and determining a separate quality metric for the current measured characteristic against each earlier measured characteristic and selecting the variable reference as a function of the determined quality metrics. In one embodiment, iteration continues only until an earlier measured characteristics is found with a quality metric that meets or exceeds a threshold value. In another embodiment, iteration continues through a plurality of earlier measured characteristic (perhaps all) and the variable reference is selected as the earlier measured characteristic with the highest quality metric. The measured characteristics may include OFDR measurements. |
| FILED | Friday, November 10, 2023 |
| APPL NO | 18/388685 |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/35358 (20130101) G01D 5/35393 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/3206 (20130101) Original (OR) Class G01K 2007/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094997 | Perlin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ColdQuanta, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | ColdQuanta, Inc. (Boulder, Colorado) |
| INVENTOR(S) | Michael Alexandrovich Perlin (Chicago, Illinois) |
| ABSTRACT | Compiling a program specification that comprises at least one quantum circuit associated with both a set of quantum operations and a first schedule for the set of quantum operations includes assigning each quantum operation in the set to a first passed set, a first caught set, or a first blocked set. The first blocked set includes a first quantum operation that addresses one or more qubits that are addressed by at least one quantum operation in the first caught set. A first passed set ordering is determined. A first caught set ordering is determined. Determining a second schedule for the set of quantum operations includes assigning the quantum operations in the first caught set to be performed after the quantum operations in the first passed set, and assigning the quantum operations in the first blocked set to be performed after the quantum operations in the first caught set. |
| FILED | Thursday, May 18, 2023 |
| APPL NO | 18/199075 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/41 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240095435 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (ARMONK, New York); New Jersey Institute of Technology (Newark, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shun Zhang (San Mateo, California); Xin Zhang (Chappaqua, New York); Shaoze Fan (East Newark, New Jersey); Ningyuan Cao (Countryside, Illinois); Jing Li (Clifton, New Jersey); Xiaoxiao Guo (Mountain View, California); Chuang Gan (Cambridge, Massachusetts) |
| ABSTRACT | A method, system, and computer program product for circuit design automation. The method identifies a set of circuit components for a proposed circuit design. A subset of circuit components is selected to generate an initial topology for the proposed circuit design. A set of subsequent topologies are iteratively generated by a heuristic search algorithm based on the subset of circuit components and the initial topology. A set of valid topologies of the set of subsequent topologies are determined by a circuit simulator based on the subset of circuit components and a set of connections within the set of subsequent topologies. The method generates the proposed circuit design from the set of valid topologies. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/932538 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/398 (20200101) Original (OR) Class G06F 2119/02 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096454 | SCHWARTZ et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Johanna Jesse SCHWARTZ (Livermore, California); Marissa WOOD (Oakland, California); Jianchao YE (Tracy, California); Adam JAYCOX (Livermore, California); Xiaoting ZHONG (Livermore, California); Aldair GONGORA (Oakland, California) |
| ABSTRACT | The present disclosure relates to systems and methods for screening a formulation of a material being printed in an additive manufacturing process, in situ, to enable rapid analysis, modeling and modification of at least one characteristic associated with the material formulation. In one embodiment the system includes a computer and an experimental planning software module that includes a historical database of sample material test results, a machine learning software module, and a new batch formulation generation software module. The experimental planning software module enables new material formulations to be determined in situ and in real time, using one or more machine learning models, and new material samples to be printed in accordance with newly determined material formulations, for closer inspection and evaluation of at least one desired characteristic of the sample materials. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/468563 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/209 (20170801) B29C 64/245 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/64 (20190201) Original (OR) Class G16C 20/70 (20190201) G16C 20/90 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096936 | Hitchcock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Collin William Hitchcock (Clifton Park, New York); Reza Ghandi (Niskayuna, New York) |
| ABSTRACT | A super-junction (SJ) device includes a first epitaxial (epi layer) that forms a first SJ layer of the SJ device and includes a second epi layer disposed on the first SJ layer that forms a device layer of the SJ device. An active area and a termination area of the first epi layer includes a first set of SJ pillars that have a particular doping concentration of a first conductivity type and a second set of SJ pillars that have the particular doping concentration of a second conductivity type. A termination area of the second epi layer includes one or more implanted regions that form a junction termination that overlaps with at least one SJ pillar of the first set of SJ pillars or the second set of SJ pillars in the termination area of the first epi layer. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 17/948670 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0634 (20130101) Original (OR) Class H01L 29/1037 (20130101) H01L 29/1608 (20130101) H01L 29/7827 (20130101) H01L 29/66068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097240 | Ernst et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy C. Ernst (Columbus, Indiana); Jonathan A. Dickson (Columbus, Indiana); Manik Narula (Columbus, Indiana) |
| ABSTRACT | A cooling system for an electrified vehicle includes a first cooling loop for circulating coolant for cooling at least one of power electronics and a motor/generator of the vehicle. The first coolant loop includes a heat exchanger for exchanging heat with the coolant in the first cooling loop. A second cooling loop is provided for circulating coolant for cooling a battery of the vehicle. The second cooling loop includes a coolant chiller connected to a refrigeration system of the vehicle for exchanging heat in the coolant received from the battery with the refrigeration system of the vehicle. |
| FILED | Wednesday, November 15, 2023 |
| APPL NO | 18/509701 |
| CURRENT CPC | Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles B60H 1/00278 (20130101) B60H 1/00392 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 58/26 (20190201) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/66 (20150401) Original (OR) Class H01M 10/613 (20150401) H01M 10/625 (20150401) H01M 10/635 (20150401) H01M 10/6568 (20150401) H01M 2220/20 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20263 (20130101) H05K 7/20272 (20130101) H05K 7/20927 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097572 | Cao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuliang Cao (Blacksburg, Virginia); Yijie Bai (Christiansburg, Virginia); Vladimir Mitrovic (Arlington, Virginia); Boran Fan (Blacksburg, Virginia); Dong Dong (Blacksburg, Virginia); Rolando Burgos (Blacksburg, Virginia) |
| ABSTRACT | Power systems including converters that exhibit reduced common mode voltage emissions are described. In one example, a power converter system includes an input and an output, a multi-level switch bridge coupled between the input and the output, an input capacitor branch coupled across the input, an output capacitor branch coupled across the output, and a controller configured to generate switching control signals for the multi-level buck-boost switch bridge. The multi-level switch bridge also includes a plurality of inductors in one example. In one case, a quadrangular or quadrangle control mode can be relied upon to switch the multi-level switch bridge, to minimize the ripple in the inductors, achieve zero voltage switching, reduce common mode electromagnetic interference emission by the converter, and for other benefits. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/932399 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 3/33573 (20210501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097593 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Boran Fan (Blacksburg, Virginia); Jagadeesh K. Tangudu (South Windsor, Connecticut); Rolando Burgos (Blacksburg, Virginia); Vladimir Blasko (Avon, Connecticut); Dong Dong (Blacksburg, Virginia) |
| ABSTRACT | A multi-three-phase motor drive system includes a power distribution network, a motor drive unit, and a motor network. The power distribution network includes a partitioned direct current (DC) link connected between a positive voltage rail and a negative voltage rail. A connection between the positive voltage rail and a mid-point node defines an upper portion of the partitioned DC link and a connection between negative voltage rail and the mid-point node defines a lower portion of the partitioned DC link. The motor drive unit includes a plurality of inverter units, and the motor network includes a plurality of motor windings which are each connected to a respective inverter unit. A first group of the inverter units is connected in parallel with the upper portion of the portioned DC link, and a second group of the inverter units is connected in parallel with the lower portion of the partitioned DC link. |
| FILED | Friday, July 14, 2023 |
| APPL NO | 18/352343 |
| CURRENT CPC | Dynamo-electric Machines H02K 11/33 (20160101) H02K 2213/03 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 27/06 (20130101) Original (OR) Class H02P 29/50 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097612 | Forrest |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan) |
| ABSTRACT | An optoelectronic system comprising a flexible optoelectronic device, wherein the device comprises a flexible plastic substrate, a coating comprising a glass or a polymer, positioned over the flexible plastic substrate, an anode and a cathode positioned over the coating, an organic heterojunction positioned between the anode and the cathode, comprising a donor material and an acceptor material, and an encapsulating layer comprising a glass or a polymer, positioned over the anode and the cathode. The device further comprises a roller configured to roll the flexible optoelectronic device into a stored position and a frame configured to mount the roller and the optoelectronic device. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/469914 |
| CURRENT CPC | Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 30/10 (20141201) H02S 30/20 (20141201) Original (OR) Class Organic electric solid-state devices H10K 30/30 (20230201) H10K 30/82 (20230201) H10K 30/88 (20230201) H10K 77/111 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240098878 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Waltham, Massachusetts) |
| INVENTOR(S) | Yongduk Lee (Vernon, Connecticut); Ankit Gupta (Willimantic, Connecticut); Abbas A. Alahyari (Glastonbury, Connecticut); Parag M. Kshirsagar (South Windsor, Connecticut) |
| ABSTRACT | Direct pin-fin cooling assemblies are disclosed for a high-power printed circuit boards (PCBs). The disclosure can solve the classical coldplate problem associated with liquid cooling of high-power PCBs namely: (1) Inhomogeneous cooling due to the calorimetric heating up of the coolant, (2) thermal interface material (TIM) related quality issues such as dry-out effects, (3) high cost due to complicated metal coldplate structure, and (4) low thermal conductivity due to multi-layer structure. This includes incorporating pin-fin direct cooling into high-power PCB structures without additional coldplate structure or TIM. In this approach, a TIM and a top plate of coldplate can be removed. Thus, the cooling performance can be improved because the thermal conductivity between a liquid coolant and a power device is increased. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/946160 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0209 (20130101) Original (OR) Class H05K 3/303 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240091162 | MARGOLIS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kara MARGOLIS (New York, New York); Mark ANSORGE (New York, New York); Kam W. LEONG (New York, New York); Letao YANG (New York, New York); Yuefei ZHU (New York, New York) |
| ABSTRACT | The present disclosure provides, inter alia, compositions and methods for treating or ameliorating the effect of a disorder such as, e.g., anxiety or depression in a subject, with less or no off- and/or on-target side effects. Also provided are methods for treating such disorder in a pregnant woman. |
| FILED | Monday, November 20, 2023 |
| APPL NO | 18/514903 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/143 (20130101) A61K 9/501 (20130101) Original (OR) Class A61K 9/5115 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091762 | Schulte et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Samuel J. Schulte (Pasadena, California); Jining Huang (Pasadena, California); Nikhil T. Linaval (Pasadena, California); Niles A. Pierce (South Pasadena, California) |
| ABSTRACT | The present disclosure relates to an HCR lateral flow device for amplified detection of a target in a sample and methods of using the same. In some embodiments, the device and methods of use combine the sensitivity of HCR signal amplification with the simplicity of the lateral flow assay format to facilitate user-friendly amplified detection of a target in a sample. |
| FILED | Wednesday, September 13, 2023 |
| APPL NO | 18/466726 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) Original (OR) Class B01L 2300/069 (20130101) B01L 2300/0825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240092509 | Sauder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Jonathan Sauder (La Crescenta, California); Nacer E. Chahat (Altadena, California); Juan M. Mejia-Ariza (Pasadena, California) |
| ABSTRACT | A device can be configured as an under-constrained deployable system. Such a system can use under-constrained deployable couplers. A device may include a second segment coupled to the first segment by a high strain structure, wherein the high strain structure is bent to store deployment energy in a stowed configuration. Releasing the stored deployment energy can allow an under-constrained deployable system to transition to an expanded configuration. A tensioning system can transition an under-constrained deployable system to a deployed configuration. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/468611 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 3/00 (20130101) B64G 4/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093821 | Mehr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mehrad Mehr (Morristown, New Jersey); Robert Mantz (Clifton, New Jersey); Bahram Jadidian (Watchung, New Jersey) |
| ABSTRACT | An assembly includes a first tube. The first tube includes a first end configured to receive a second tube. The second tube includes a first end configured to slidably translate into the first end of the first tube and to receive an insert. The insert is configured to be disposed within a first portion of the second tube that is near the first end of the second tube. The first tube, the second tube, and the insert form a seal. The coefficient of thermal expansion (CTE) of the first tube is similar to the CTE of the insert and different from the CTE of the second tube. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/933392 |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 25/0072 (20130101) F16L 51/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094111 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AUBURN UNIVERSITY (Auburn, Alabama); NASA/MARSHALL SPACE FLIGHT CENTER (MSFC, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhongyang Cheng (Auburn, Alabama); Terry Dewayne Rolin (MFSC, Alabama); Yaqub Adediji (Auburn, Alabama); Jindong Wei (Auburn, Alabama) |
| ABSTRACT | The invention in one aspect relates to a method for nondestructively detecting corrosion of an object such as metallic cables. The method includes applying an electronic signal to a device under test (DUT) including said object; measuring signal-transmission characteristics of said object; and determining the corrosion of the object based on the measured signal-transmission characteristics of said object. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/370138 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 17/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097381 | Shasho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeybee Robotics, LLC (Longmont, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey I. Shasho (Brooklyn, New York); Jonah E. Saltzman (Brooklyn, New York) |
| ABSTRACT | A joint system for constructing orbital and extra-terrestrial structures includes a node receptacle having a node surface and a finger receiver projecting outwardly of the node surface, and a strut element including a support member, a finger element shiftably supported on the support member, a shell system shiftably supported on the support member and connected to the finger element, and an actuator mounted to the support member and operatively connected with the shell system. The actuator is operable to shift the finger element and the shell system into contact with the node receptacle. The finger element cooperates with the finger receiver to form a first load path and the shell system cooperating with the node surface to form a second load path. |
| FILED | Tuesday, November 21, 2023 |
| APPL NO | 18/516126 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 99/00 (20220801) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/502 (20130101) H01R 13/62927 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20240091279 | Mangalam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of lowa Research Foundation (Iowa City, Iowa); The United States Government, as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ashutosh Mangalam (Iowa City, Iowa); Shailesh K. Shahi (Iowa City, Iowa); Sudeep Ghimire (Iowa City, Iowa); Samantha Jensen (New York, New York) |
| ABSTRACT | A method to prevent, inhibit or treat an inflammatory disease in a mammal, is provided that includes administering to a mammal in need thereof an effective amount of one or more isolated gut microbes and one or more phytoestrogens. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/464152 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) A61K 35/741 (20130101) Original (OR) Class A61K 2035/115 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240091429 | Kelley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Kelley (Chelmsford, Massachusetts) |
| ABSTRACT | An external catheter system can comprise an external catheter comprising an engagement portion that is configured to receive and sealingly engage at least a portion of a penis of a user and an outlet. The system can further comprise a negative pressure source. A conduit can couple the negative pressure source to the external catheter. At least one of the external catheter and the conduit can comprise a portion that, upon application of a negative pressure by the negative pressure source, is configured to collapse to provide a pressure drop between the negative pressure source and the engagement portion of the external catheter. |
| FILED | Wednesday, October 11, 2023 |
| APPL NO | 18/484617 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/90 (20210501) Original (OR) Class A61M 2202/0496 (20130101) A61M 2205/0216 (20130101) A61M 2210/167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240096470 | Strohbehn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Garth William Strohbehn (Ann Arbor, Michigan); Philip Simon Boonstra (Ann Arbor, Michigan) |
| ABSTRACT | Methods, systems and apparatuses for dose optimization is disclosed. A predetermined threshold may be assigned to a medication. Dose-responses from each subject of a plurality of subjects may be collected and evaluated so that a determination may be made regarding whether a particular dose is equal to a true minimum dose with satisfactory efficacy value. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/370603 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/10 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20240091349 | Talaat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adel M. Talaat (Madison, Wisconsin); Shaswath Chandrasekar (Madison, Wisconsin) |
| ABSTRACT | Quil-A chitosan spherical nanostructure complexes as well as methods of making and using such complexes are disclosed herein. Also provided are Quil-A chitosan spherical nanostrucutres loaded with one or more RNA, DNA, or protein payload molecules as well as methods of making and using such loaded complexes. |
| FILED | Wednesday, August 16, 2023 |
| APPL NO | 18/450908 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 39/215 (20130101) A61K 2039/55577 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093215 | Maselko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maciej Maselko (Sydney, Australia); Mike Smanski (Falcon Heights, Minnesota) |
| ABSTRACT | This disclosure describes, in one aspect, a cell that includes a biocontainment system. Generally, the biocontainment system includes a coding region whose overexpression decreases growth of the cell, a transcription regulatory region that includes a silent mutation and is operably linked upstream of the coding region, and a polynucleotide that encodes a programmable transcription activator engineered to bind to the transcription regulatory region in the absence of the silent mutation. Thus, in the absence of the silent mutation, the programmable transcription activator induces overexpression of the coding region; in the presence of the silent mutation, the programmable transcription activator does not initiate overexpression of the coding region. |
| FILED | Friday, July 07, 2023 |
| APPL NO | 18/219524 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/18 (20130101) C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/80 (20130101) C12N 15/81 (20130101) C12N 15/815 (20130101) C12N 15/8216 (20130101) C12N 15/8217 (20130101) C12N 15/8218 (20130101) Original (OR) Class C12N 15/8263 (20130101) C12N 15/8265 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20240092501 | Simms |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christine M. Simms (North Liberty, Iowa) |
| ABSTRACT | An aircraft is described. The aircraft includes an avionics management system including one or more control display units. The control display units include an alphanumeric keyboard. By the alphanumeric keyboard, an operator within the aircraft may input a personal identification number (PIN). The input PIN is received from the alphanumeric keyboard and compared with a PIN stored in memory. When the input PIN is validated, the avionics management system changes a system state from not validated to validated, thereby permitting the control display unit to access otherwise unavailable mobile user objective system (MUOS) feature sets, such as viewing MUOS presets or tuning to the MUOS presets. |
| FILED | Wednesday, August 03, 2022 |
| APPL NO | 17/880168 |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/0015 (20130101) Original (OR) Class Transmission H04B 7/18506 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240098503 | Lim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Jason Lim (Alexandria, Virginia); Daniel Boyd (Arlington, Virginia); Chang Ellison (Arlington, Virginia); William Washington (North Potomac, Maryland) |
| ABSTRACT | In an example, a provider system receives from a client device a request for client access. The provider system sends to the client device a request for identification information of the client. The provider system receives client information associated with a mobile identification credential (MIC) which the client device received from an authorizing party system (APS), the client having consented to release the client information to the provider system, and the client information having been verified by the APS. The provider system uses the verified client information associated with the MIC to verify or not verify the identity of the client. The provider system verifies the identity of the client before granting the client the request for client access. |
| FILED | Wednesday, November 22, 2023 |
| APPL NO | 18/517807 |
| CURRENT CPC | Wireless Communication Networks H04W 12/06 (20130101) H04W 12/08 (20130101) H04W 12/71 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20240093826 | Benincosa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REDUCT NV (, None) |
| ASSIGNEE(S) | REDUCT NV (Schelle, Belgium) |
| INVENTOR(S) | William Benincosa (Chicago, Illinois); Dennis Jarnecke (River Forest, Illinois); Jeff Mainzer (Wheeling, Illinois); Francis X. Hennessey III (Arlington Heights, Illinois); Jason Sphar (Mount Prospect, Illinois); Otto Ballintijn (Schilde, Belgium); Hans Vannieuwenhuyze (Wilrijk, Belgium); Daan Tamsyn (Londerzeel, Belgium) |
| ABSTRACT | Method and system for mapping and/or inspecting an underground pipeline infrastructure, using: a sensor probe for collecting geospatial data while travelling through a pipeline of the pipeline infrastructure, and a driving mechanism comprising a tether, for driving the sensor probe, wherein the sensor probe is provided to enter the pipeline at a vertical angle through a live-fluid entry apparatus and once inside the pipeline make a 90° angle change of direction to align with the orientation of the pipeline. |
| FILED | Friday, November 26, 2021 |
| APPL NO | 18/039827 |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 55/28 (20130101) Original (OR) Class F16L 55/46 (20130101) F16L 55/48 (20130101) F16L 2101/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240098451 | Kassas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zak Kassas (Columbus, Ohio); Joe Khalife (Irvine, California) |
| ABSTRACT | Processes and device configurations are provided for navigation using communications signal observables and using differential and non-differential frameworks. Communication signals, such as cellular communication signals may be used to obtain position estimates of a device such as a rover or unmanned aerial vehicle. Frameworks are provided for determination of position estimates with and without the use of a base station device. Processes can include use of position estimates to aid navigation. |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 18/548566 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/009 (20130101) G01S 5/0205 (20130101) Transmission H04B 7/2628 (20130101) Wireless Communication Networks H04W 4/024 (20180201) Original (OR) Class H04W 4/40 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
General Services Administration (GSA)
| US 20240097906 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tenet 3, LLC (Dayton, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kelce S. Wilson (Murphy, Texas); Jeff A. Hughes (Dayton, Ohio); Tyler J. Moody (Fairborn, Ohio); Derek E. Doran (Hilliard, Ohio); Gary R. Tuttle (Middletown, Ohio); Joel B. Rieman (Xenia, Ohio) |
| ABSTRACT | A permissioned blockchain, using off-chain storage, provides advantages over blockchains that rely on consensus and/or store information within the blockchain. Advantages include enhanced viability, compactness, and the ability to register material with distribution limitations (e.g., military classified). Examples create an immutable public record of data signatures that confirm when data is intact, without distributing the data itself, so that widespread availability of the blockchain (beyond those privileged to see the data) advantageously increases the size of the community that is able to detect spoofing or forgery attempts. A permissioning entity limits submissions to manage blockchain growth, foreclosing problematic material that may risk long-term viability. Examples render blockchain operations resistant to advanced persistent threats (APTs), leverage digital signatures as additional trust elements for high-risk data, link records to track pedigree and enable identification of superseded (obsolete) data, and leverage out-of-band date proof to enable independent verification of integrity and no-later-than data-of-existence. |
| FILED | Friday, November 17, 2023 |
| APPL NO | 18/513194 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/64 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/50 (20220501) H04L 9/3218 (20130101) Original (OR) Class H04L 9/3239 (20130101) H04L 9/3247 (20130101) H04L 63/1483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240097907 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tenet 3, LLC (Dayton, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kelce S. Wilson (Murphy, Texas); Jeff A. Hughes (Dayton, Ohio); Tyler J. Moody (Fairborn, Ohio); Derek E. Doran (Hilliard, Ohio); Gary R. Tuttle (Middletown, Ohio); Joel B. Rieman (Xenia, Ohio) |
| ABSTRACT | A permissioned blockchain, using off-chain storage, provides advantages over blockchains that rely on consensus and/or store information within the blockchain. Advantages include enhanced viability, compactness, and the ability to register material with distribution limitations (e.g., military classified). Examples create an immutable public record of data signatures that confirm when data is intact, without distributing the data itself, so that widespread availability of the blockchain (beyond those privileged to see the data) advantageously increases the size of the community that is able to detect spoofing or forgery attempts. A permissioning entity limits submissions to manage blockchain growth, foreclosing problematic material that may risk long-term viability. Examples render blockchain operations resistant to advanced persistent threats (APTs), leverage digital signatures as additional trust elements for high-risk data, link records to track pedigree and enable identification of superseded (obsolete) data, and leverage out-of-band date proof to enable independent verification of integrity and no-later-than data-of-existence. |
| FILED | Friday, November 17, 2023 |
| APPL NO | 18/513235 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/64 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/50 (20220501) H04L 9/3218 (20130101) Original (OR) Class H04L 9/3239 (20130101) H04L 9/3247 (20130101) H04L 63/1483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20240091831 | Quigley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut); Nicole Neff (North Potomac, Maryland); Jack Rowbottom (Swansea, Massachusetts) |
| ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system comprising a plurality of wells are provided herein. In some embodiments, the method comprises obtaining a concentration of a greenhouse gas measured a distance above a surface of a region comprising the plurality of wells; determining whether the measure of the concentration of the greenhouse gas is greater than a first threshold; and in response to determining that the measure of the concentration of the greenhouse gas is greater than the first threshold, increasing a flow rate of landfill gas being extracted from at least one well of the plurality of wells. |
| FILED | Wednesday, November 22, 2023 |
| APPL NO | 18/517492 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class B09B 2101/25 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240094103 | Salem et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MRL MATERIALS RESOURCES LLC (Xenia, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ayman A. Salem (Beavercreek, Ohio); Michelle Harr (Xenia, Ohio); Adam Pilchak (Xenia, Ohio); Daniel P. Satko (Centerville, Ohio) |
| ABSTRACT | A process for testing material samples comprises stressing samples under test by bending the samples with a bending fatigue system. During testing, an optical system takes images of the samples and cracks are identified in the samples using the images. Input variables and spatial variables for use in microstructure analysis of the images are determined and used to create a model. Based on the model, crack growth rates are predicted for untested microstructures based on the samples based on the analysis of the images. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/174507 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/20 (20130101) Original (OR) Class G01N 3/068 (20130101) G01N 2203/0066 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0455 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20240094316 | Russek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen E. Russek (Louisville, Colorado); Karl Francis Stupic (Westminster, Colorado) |
| ABSTRACT | A hyperpolarization micro-magnetic resonance imager for three-dimensional imaging of a biological composition with cellular resolution includes a hyperpolarizer source, hyperpolarizer transmission line, an NMR console, a nuclear magnetic resonance tuned circuit, an imaging cell, a magnet, a gradient-shim coil, a Hall probe and thermometer, and a printed circuit board. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/370205 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/07 (20130101) G01R 33/282 (20130101) Original (OR) Class G01R 33/3852 (20130101) G01R 33/3875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 20240093890 | Goswami et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Molekule Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dilip N. Goswami (San Francisco, California); Philip Myers (San Francisco, California) |
| ABSTRACT | An air purification system including a filter assembly including a substrate including a fibrous media, and a photocatalytic material disposed on the substrate, wherein the photocatalytic material includes a first quantity of crushed nanostructures; and a photon source arranged to illuminate the photocatalytic material with optical radiation. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 16/831354 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 9/22 (20130101) A61L 9/205 (20130101) Original (OR) Class A61L 2209/14 (20130101) A61L 2209/15 (20130101) A61L 2209/21 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/004 (20130101) B01J 35/023 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20240095184 | Gutierrez |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Anthony Thomas Gutierrez (Seattle, Washington) |
| ABSTRACT | Address translation service management techniques are described. These techniques are based on metadata that is usable to provide a hint as insight into memory access, and based on this, use of a translation lookaside buffer is optimized to control which entries are maintained in the queue and manage address translation requests. |
| FILED | Wednesday, September 21, 2022 |
| APPL NO | 17/949716 |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0882 (20130101) G06F 12/1027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20240093157 | Tuan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Rocky S. Tuan (Pittsburgh, Pennsylvania); Hang Lin (Pittsburgh, Pennsylvania); Thomas P. Lozito (Pittsburgh, Pennsylvania); Peter Alexander (Wexford, Pennsylvania); Douglas Allen Nelson, Jr. (Pittsburgh, Pennsylvania); Riccardo Gottardi (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are various bioreactor devices and systems for growing cellular material, and related methods of growing cellular material. In some cases, a system can include a well plate having a plurality of wells and a bioreactor situated in each well of the well plate. In some cases, a bioreactor can include an inner body which divides the bioreactor into several distinct chambers and facilitates the growth of a multi-tissue sample in the bioreactor. In some cases, a system can include a mechanical actuator situated to mechanically stress tissues grown in a bioreactor. |
| FILED | Wednesday, November 15, 2023 |
| APPL NO | 18/510350 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/12 (20130101) C12M 23/16 (20130101) C12M 23/34 (20130101) C12M 35/04 (20130101) C12M 35/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0697 (20130101) Original (OR) Class C12N 2502/1311 (20130101) C12N 2502/1317 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20240095658 | Turner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alison Frankowski Turner (Arlington, Virginia); Farah Bandukwala (Herndon, Virginia) |
| ABSTRACT | The integrated logistics ecosystem is a hybrid system for creating datasets and services that are utilized in a logistics network. This system provides an inventory of data objects, access layers, and services which perform across various tenants of the system. These tenants may be made up of several architectural components such as transportation management, freight payment, integrated GPS, transportation visibility, logistics gateway, contract management system, freight auction, fuel management, surface visibility, workforce management, and integrated control tower components. Each of these is integrated into the system as a whole to ensure dynamic communication and process execution. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/470898 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0833 (20130101) G06Q 10/08355 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20240093479 | Mistry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yash Mistry (Tempe, Arizona); Siying Liu (Gilbert, Arizona); Mandar Shinde (Tempe, Arizona); Xiangfan Chen (Chandler, Arizona); Dhruv Bhate (Scottsdale, Arizona); Nikhilesh Chawla (West Lafayette, Indiana); Swapnil Morankar (West Lafayette, Indiana); Clint Penick (Kennesaw, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yash Mistry (Tempe, Arizona); Siying Liu (Gilbert, Arizona); Mandar Shinde (Tempe, Arizona); Xiangfan Chen (Chandler, Arizona); Dhruv Bhate (Scottsdale, Arizona); Nikhilesh Chawla (West Lafayette, Indiana); Swapnil Morankar (West Lafayette, Indiana); Clint Penick (Kennesaw, Georgia) |
| ABSTRACT | A unit cell of an interwoven lattice structure having an interwoven point therein. The unit cell includes first, second, third, and fourth struts each having an interwoven node offset from the interwoven point. The first strut has a first interwoven node offset from a first diagonal unit cell plane in a first distance and first direction. The second strut has a second interwoven node offset from the first diagonal unit cell plane in a second distance and second direction opposite the first direction. The third strut has a third interwoven node offset from a second diagonal unit cell plane in a third distance and third direction. The fourth strut has a fourth interwoven node offset from the second diagonal unit cell plane in a fourth distance and fourth direction opposite the third direction. The first and second diagonal unit cell planes both pass through the interwoven point. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/468185 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/182 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/19 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240093609 | Conner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Richard David Conner (Peoria, Arizona); Ryan Cox (Gilbert, Arizona); Josef Merki (Chandler, Arizona); Brian Larsen (Downey, California) |
| ABSTRACT | A ram air turbine rotor comprises at least one intra-flow path shroud structure coupled between rotor blades, along a radial position between a support disc and an outer rim. The shroud structure includes shroud sectors each coupled between a respective pair of blades. The sectors each include a first edge adjacent to leading edges of the respective pair of blades, the first edge including a first curved segment, and a second edge adjacent to trailing edges of the respective pair of blades, the second edge including a second curved segment. The curved segments are each partially defined by a respective ellipse having a semi-major axis and a semi-minor axis. The semi-major axis is a portion of a spanwise distance between the respective pair of blades. The semi-minor axis is a portion of an axial distance between the leading edge of one blade and the trailing edge of an adjacent blade. |
| FILED | Thursday, August 03, 2023 |
| APPL NO | 18/365118 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/03 (20130101) F01D 5/10 (20130101) Original (OR) Class F01D 5/022 (20130101) F01D 5/143 (20130101) Wind Motors F03D 1/0633 (20130101) F03D 9/32 (20160501) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2220/31 (20130101) F05B 2240/33 (20130101) F05B 2240/923 (20130101) F05B 2250/14 (20130101) F05B 2250/141 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240098001 | KIM et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kevinlab Co. (Ansan-si, South Korea) |
| ASSIGNEE(S) | Kevinlab Co. (Ansan-si, South Korea) |
| INVENTOR(S) | Kyung Hak KIM (Suwon-si, South Korea); Sung Hwan CHOI (Seoul, South Korea) |
| ABSTRACT | The present disclosure relates to a data management system and method and, more particularly, to a data management system and method using a docker system in an edge computing environment, the system and method collecting and managing data for each of control operation targets and each of characteristic of the control operation targets using a docker system in an edge computing-cloud computing linkage environment, and enabling an edge server to stably operate in accordance with the characteristics of the control operation targets even though communication between the edge server of an edge computing environment and a cloud server is impossible. |
| FILED | Tuesday, September 12, 2023 |
| APPL NO | 18/465673 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/04 (20130101) H04L 43/065 (20130101) Original (OR) Class H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, March 21, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240321.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page