FedInvent™ Patent Applications
Application Details for Thursday, April 04, 2024
This page was updated on Tuesday, June 18, 2024 at 02:18 PM GMT
Department of Health and Human Services (HHS)
| US 20240108241 | Langer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Robert S. Langer (Newton, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts); Malvika Verma (Cambridge, Massachusetts); Feyisope Eweje (Jacksonville, North Carolina); Christoph Winfried Johannes Steiger (Cambridge, Massachusetts); Junwei Li (Cambridge, Massachusetts); Nhi Phan (Somerville, Massachusetts); Hen-Wei Huang (Cambridge, Massachusetts); Jacqueline Chu (Boston, Massachusetts); John Ashraf Fou Salama (Cambridge, Massachusetts) |
| ABSTRACT | Drug delivery articles, resident articles, and retrieval systems e.g., for gram-level dosing, are generally provided. In some embodiments, the residence articles are configured for transesophageal administration, transesophageal retrieval, and/or gastric retention to/in a subject. In certain embodiments, the residence article includes dimensions configured for transesophageal administration with a gastric resident system. In some cases, the residence article may be configured to control drug release e.g., with zero-order drug kinetics with no potential for burst release for weeks to months. In some embodiments, the residence articles described herein comprise biocompatible materials and/or are safe for gastric retention. In certain embodiments, the residence article includes dimensions configured for transesophageal retrieval. In some cases, the residence articles described herein may comprise relatively large doses of drug (e.g., greater than or equal to 1 gram). |
| FILED | Friday, December 15, 2023 |
| APPL NO | 18/541818 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/073 (20130101) Original (OR) Class A61B 5/4845 (20130101) A61B 2562/02 (20130101) A61B 2562/162 (20130101) A61B 2562/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108257 | MUJEEB-U-RAHMAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | Integrated Medical Sensors, Inc. (Irvine, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MUHAMMAD MUJEEB-U-RAHMAN (IRVINE, California); MEISAM HONARVAR NAZARI (IRVINE, California); MEHMET SENCAN (TUSTIN, California) |
| ABSTRACT | A multi-analyte sensor system is provided, comprising: a transmitter for containing a battery the transmitter being for placement on top of patient skin; and an implantable multianalyte monolithic integrated circuit for placement beneath the patient skin, wherein the implantable multianalyte monolithic integrated circuit comprises a sensor control circuit (e.g., Potentiostat, Voltametric Circuit) and an electrochemical sensing element, wherein the electrochemical sensing element is configured to sense concentrations of two or more analytes and generate an electrical signal representative of these concentrations, and wherein sensor control circuit is electrically connected to the electrochemical sensing element and enables independent control of detection method and conditions (e.g., redox potential) at the integrated sensing circuit. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/553733 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 5/1473 (20130101) Original (OR) Class A61B 2562/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108276 | FUHRMAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jordan D. FUHRMAN (Chicago, Illinois); Ali MANSOUR (Chicago, Illinois); Maryellen L. GIGER (Elmhurst, Illinois); Fernando D. GOLDENBERG (Chicago, Illinois) |
| ABSTRACT | A method for identifying the presence or progression of hypoxic ischemic brain injury includes, for each subset of one or more subsets of a three-dimensional medical image of a head of a patient: (i) inputting said each subset into a machine-learning model, (ii) extracting one or more features or feature maps from the machine-learning model, and (iii) constructing, based on the one or more features or feature maps, one of a sequence of vectors. The sequence of vectors is then pooled to obtain a scan-level vector that is used to obtain a score indicating HIBI presence or progression in the patient. For example, the scan-level vector can be inputted into a pre-trained classifier that generates the score based on the scan-level vector. The machine-learning model may be a pre-trained conventional neural network or support vector machine. |
| FILED | Tuesday, February 01, 2022 |
| APPL NO | 18/274819 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/4064 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10081 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108553 | Pineda et al. |
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| FUNDED BY |
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| APPLICANT(S) | Preemie-Pacer, LLC (O'Fallon, Missouri) |
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| INVENTOR(S) | Roberta Pineda (Altadena, California); Jeffrey Macler (Tecumseh, Missouri) |
| ABSTRACT | An infant feeding device intended for oral feeding of premature infants. The device is adapted to regulate the flow of fluid fed to the infant. The device may also be adapted to receive and record data relevant to each feeding session. The device further includes disposable components that are appropriate for contact with human milk and formula. |
| FILED | Thursday, September 29, 2022 |
| APPL NO | 17/956199 |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 9/006 (20130101) Original (OR) Class A61J 2200/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108575 | CROYLE et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Maria A. CROYLE (Austin, Texas); Jin Huk CHOI (Austin, Texas); Stephen Clay SCHAFER (Austin, Texas) |
| ABSTRACT | Vaccine compositions that may be administered to a subject via the buccal and/or sublingual mucosa are provided. Methods for administration and preparation of such vaccine compositions are also provided. |
| FILED | Thursday, October 12, 2023 |
| APPL NO | 18/485625 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) Original (OR) Class A61K 39/12 (20130101) A61K 47/26 (20130101) A61K 2039/5256 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/04 (20130101) C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108593 | Zhai et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| INVENTOR(S) | Rong Grace Zhai (Miami, Florida); Xianzun Tao (Miami, Florida); Chong Li (Miami, Florida); Yi Zhu (Miami, Florida); Zoraida Diaz-Perez (Miami, Florida) |
| ABSTRACT | The disclosure provides a method of treating a polyamine imbalance-related disorder. The method comprises administering phenylbutyrate to a subject in need thereof, thereby treating the polyamine imbalance-related disorder. |
| FILED | Monday, December 06, 2021 |
| APPL NO | 18/039897 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108595 | SWEET et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); UNIVERSITY OF PITTSBURGH MEDICAL CENTER (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert A. SWEET (Pittsburgh, Pennsylvania); Brandon C. MCKINNEY (Pittsburgh, Pennsylvania); LiRong WANG (Pittsburgh, Pennsylvania); Matthew Luke MACDONALD (Pittsburgh, Pennsylvania); Peihao FAN (Pittsburgh, Pennsylvania); Joshua Michael KRIVINKO (Pittsburgh, Pennsylvania) |
| ABSTRACT | Described herein are methods of treating, preventing, or reducing dendritic spine density loss in a subject, the method comprising administering a compound selected from: metformin, pentosan polysulfate, amlexanox, leflunomide, prasterone, glutathione disulfide, pazopanib, bosutinib, dabrafenib, baricitinib, or a pharmaceutically acceptable salt, prodrug, or derivative thereof; or any combination thereof; or compositions described herein. |
| FILED | Monday, September 11, 2023 |
| APPL NO | 18/464725 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/221 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 31/497 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/737 (20130101) A61K 31/5685 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108608 | Jurkunas |
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| FUNDED BY |
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| APPLICANT(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ula Jurkunas (Winchester, Massachusetts) |
| ABSTRACT | This application discloses methods and pharmaceutical compositions (e.g., oral, parenteral or topical ophthalmic formulations) for treating Fuchs endothelial corneal dystrophy (FECD). |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 18/267905 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/09 (20130101) A61K 31/352 (20130101) A61K 31/4375 (20130101) Original (OR) Class A61K 45/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108620 | SCANGARELLA-OMAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | GlaxoSmithKline Intellectual Property Development Limited (Stevenage, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole SCANGARELLA-OMAN (Collegeville, Pennsylvania); Etienne F. Dumont (Collegeville, Pennsylvania); Aline Bergesch Barth (Collegeville, Pennsylvania) |
| ABSTRACT | The present invention relates to a novel treatment method for the treatment of an infection caused by Neisseria gonorrhoeae, comprising administering gepotidacin or a pharmaceutically acceptable salt thereof to a human in need thereof, in accordance with a treatment regimen as defined herein. |
| FILED | Wednesday, November 15, 2023 |
| APPL NO | 18/509964 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/4985 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108623 | ROBICHAUX et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Jacqulyne P. ROBICHAUX (Houston, Texas); John V. HEYMACH (Houston, Texas) |
| ABSTRACT | Aspects of the present disclosure are directed to methods for treating a subject having cancer. Certain aspects relate to treating a subject for lung cancer by administering poziotinib to a subject determined, from analysis of tumor DNA from the subject, to have an EGFR mutation of a particular classification. Further aspects relate to methods for treating a subject for lung cancer by detecting an EGFR mutation of a particular classification in tumor DNA from the subject and administering an effective amount of poziotinib to the subject. Also disclosed are methods for stratifying and prognosing subjects based on EGFR mutation classification. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 18/263340 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240108628 — COMBINATION THERAPY WITH MEK INHIBITOR AND CDK4/6 INHIBITOR TO TREAT PANCREATIC CANCER
| US 20240108628 | Ruscetti et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marcus Ruscetti (New York, New York); John P. Morris, IV (New York, New York); Scott Lowe (New York, New York) |
| ABSTRACT | The present technology provides methods for treating pancreatic cancer using a MEK inhibitor and a CDK4/6 inhibitor. Also disclosed herein are methods for increasing patient responsiveness to chemotherapeutic and/or immunotherapeutic regimes for pancreatic cancer. Kits for use in practicing the methods are also provided. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/138545 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/44 (20130101) A61K 31/145 (20130101) A61K 31/185 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/535 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/4412 (20130101) A61K 31/4523 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108634 | Gera et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Gera (North Hills, California); Jacquelyn T. Saunders (Los Angeles, California); Brent Holmes (Los Angeles, California); Angelica Benavides-Serrato (Los Angeles, California); Robert N. Nishimura (Los Angeles, California) |
| ABSTRACT | Described herein are compositions and their use in methods and pharmaceutical compositions for inhibiting the binding between Yes-associated protein and TEA domain. Also, described herein are methods of using said compositions capable of inhibiting the binding between Yes-associated protein and TEA domain to treat cancer, inhibit cell proliferation, cell migration, cell invasiveness and tumor growth. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 18/274293 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108644 | OBRADOVIC et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aleksandar OBRADOVIC (New York, New York); Casey Roy AGER (New York, New York); Andrea CALIFANO (New York, New York); Charles G. DRAKE (New Hope, Pennsylvania) |
| ABSTRACT | Described herein is a therapeutic method that specifically addresses tumor-infiltrated regulatory T cells (Tregs) with minimal impact on the peripheral Tregs. |
| FILED | Monday, November 13, 2023 |
| APPL NO | 18/507851 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/7068 (20130101) Original (OR) Class A61K 31/7072 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108646 | ZAGER et al. |
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| FUNDED BY |
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| APPLICANT(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard A. ZAGER (Seattle, Washington); Ali CM JOHNSON (Mill Creek, Washington) |
| ABSTRACT | The present disclosure provides compositions, kits, and methods to protect organs by inducing acquired cytoresistance without causing injury to the organ. The compositions, kits, and methods utilize heme proteins, iron and/or vitamin B12 and, optionally, agents that impact heme protein metabolism. |
| FILED | Tuesday, September 12, 2023 |
| APPL NO | 18/465768 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/194 (20130101) A61K 31/555 (20130101) A61K 31/714 (20130101) Original (OR) Class A61K 33/26 (20130101) A61K 38/42 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108662 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Wang (Chapel Hill, North Carolina); Kin Man Au (Chapel Hill, North Carolina) |
| ABSTRACT | Described herein are functionalized cells comprising an immune checkpoint molecule covalently attached to the cell surface or to a nanoparticle attached to the cell surface, and compositions comprising the functionalized cells. Also described are acellular pancreatic extracellular matrices comprising a functionalized cell(s) and decellularized pancreatic-derived protein(s). Also described are methods of treating disease by administering to subjects the functionalized cells and acellular pancreatic extracellular matrices. Also described are methods of making the functionalized cells and acellular pancreatic extracellular matrices described herein. |
| FILED | Tuesday, November 23, 2021 |
| APPL NO | 18/039387 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/39 (20130101) Original (OR) Class A61K 39/001111 (20180801) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 37/04 (20180101) Peptides C07K 14/4726 (20130101) C07K 14/70532 (20130101) C07K 17/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108689 | Kuchroo et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vijay K. Kuchroo (Boston, Massachusetts); Ramnik Xavier (Cambridge, Massachusetts); Mathias Pawlak (Boston, Massachusetts); David DeTomaso (Oakland, California); Nir Yosef (Oakland, California) |
| ABSTRACT | The subject matter disclosed herein is generally directed to pathogenic Th1 cells whose phenotype is dependent on IL-23R signaling. Th1 cell specific therapeutic targets and gene programs are disclosed herein. In particular, inhibition of CD160 reduces Th1 cell pathogenicity. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 18/273579 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/22 (20130101) C12N 2310/20 (20170501) C12N 2501/2312 (20130101) C12N 2501/2321 (20130101) C12N 2501/2323 (20130101) C12N 2503/02 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108698 | Dubal |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (, None) |
| INVENTOR(S) | Dena Dubal (Oakland, California) |
| ABSTRACT | Provided herein are klotho polypeptide compositions and methods for improving cognitive function in an individual comprising treatment of with klotho polypeptides. |
| FILED | Wednesday, June 28, 2023 |
| APPL NO | 18/215276 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/47 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Enzymes C12Y 302/01031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108702 | Selsted et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael E. Selsted (Pasadena, California); Dat Q. Tran (Alhambra, California); Patti Tran (Alhambra, California); Justin B. Schaal (Orange, California); Virginia Basso (Covina, California); Prasad Tongaonkar (Arcadia, California) |
| ABSTRACT | Methods for treating and/or SARS-CoV-2 infection are described that inhibit viral replication, multiple protease activities, and provide anti-inflammatory activity. Such activities can be provided by a single species, such as a naturally occurring cyclic peptide. |
| FILED | Wednesday, January 12, 2022 |
| APPL NO | 18/273181 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/55 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108706 | Orentas et al. |
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| FUNDED BY |
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| APPLICANT(S) | LENTIGEN TECHNOLOGY, INC. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rimas J. Orentas (Seattle, Washington); Dina Schneider (Potomac, Maryland); Boro Dropulic (Ellicott City, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
| ABSTRACT | Chimeric antigen receptors (CARs) containing CD22 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the CARs are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making CAR T cells are also disclosed. |
| FILED | Monday, December 04, 2023 |
| APPL NO | 18/528012 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/001113 (20180801) Original (OR) Class A61K 2039/505 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 16/2803 (20130101) C07K 2317/21 (20130101) C07K 2317/73 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108716 | Steinmetz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicole F. Steinmetz (La Jolla, California); Oscar A. Ortega-Rivera (La Jolla, California); Jonathan K. Pokorski (La Jolla, California) |
| ABSTRACT | Provided are compositions, methods and uses relating to one or more virus or virus-like particle(s), each of which comprises at least one epitope(s) of a pathogen causing the disease or one or more of the cholesterol checkpoint protein(s). |
| FILED | Friday, January 07, 2022 |
| APPL NO | 18/271366 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0005 (20130101) A61K 39/0012 (20130101) A61K 39/215 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 2039/525 (20130101) A61K 2039/5258 (20130101) A61K 2039/6093 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108721 | Dotti et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gianpietro Dotti (Chapel Hill, North Carolina); Hongwei Du (Chapel Hill, North Carolina); Koichi Hirabayashi (Nagano, Japan); Yang Xu (Shenzhen, China PRC) |
| ABSTRACT | Disclosed herein is a chimeric antigen receptor T cell therapy for treating patients having a cancer, such as a cancer having one or more solid tumors. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 18/034669 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) Original (OR) Class A61K 39/4631 (20230501) A61K 39/464411 (20230501) A61K 39/464471 (20230501) A61K 2239/22 (20230501) A61K 2239/28 (20230501) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/2827 (20130101) C07K 16/3084 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108724 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Huang-Chiao Huang (Washington, District of Columbia); Barry Jiahao Liang (Gaithersburg, Maryland) |
| ABSTRACT | The present disclosure relates to photo-immunoconjugate formulations comprising a nanoparticle carrier comprising first and second therapeutic agents coupled to the nanoparticle carrier, and a photosensitizer molecule coupled to the first therapeutic agent or the nanoparticle carrier, and methods of treating cancer via administration of the photo-immunoconjugate formulations. |
| FILED | Thursday, June 29, 2023 |
| APPL NO | 18/344712 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) A61K 41/0057 (20130101) Original (OR) Class A61K 47/6803 (20170801) A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 47/6929 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108734 | JAMIESON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Catriona JAMIESON (San Diego, California); Wenxue MA (San Diego, California) |
| ABSTRACT | In alternative embodiments, provided are methods for treating and ameliorating a cancer such as a leukemia such as acute myeloid leukemia (AML) comprising administration to an individual in need thereof a pharmaceutical composition comprising imetelstat, or imetelstat and second drug such as dasatinib, or ruxolitinib, fedratinib, 8-aza-adenosine, raltegravir and/or dolutegravir or any combination thereof. In alternative embodiments, provided are methods for the in vivo inhibition of myeloproliferative neoplasm (MPN) or AML stem cell propagation comprising administration to an individual in need thereof a pharmaceutical composition comprising imetelstat, or imetelstat and second drug. In alternative embodiments, provided are methods for the in vivo inhibition pre-leukemia stem cell (pre-LSC) transformation into leukemia stem cells (LSCs) comprising administration to an individual in need thereof a pharmaceutical composition comprising imetelstat, or imetelstat and second drug such as dastinib, or ruxolitinib, fedratinib, 8-aza-adenosine, raltegravir and/or dolutegravir or any combination thereof. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 18/273716 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/365 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/635 (20130101) A61K 31/5383 (20130101) A61K 31/7064 (20130101) A61K 35/28 (20130101) A61K 38/50 (20130101) A61K 45/06 (20130101) A61K 47/549 (20170801) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 15/08 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 31/16 (20180101) A61P 35/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2740/15043 (20130101) Enzymes C12Y 305/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108748 | SEN GUPTA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | ANIRBAN SEN GUPTA (Cleveland, Ohio); UJJAL DIDAR SINGH SEKHON (Cleveland, Ohio) |
| ABSTRACT | A nanoparticle and/or microparticle construct for therapeutic applications includes a plurality of targeting moieties that bind to target molecules of a cell, tissue, and/or disease site in a subject, phosphatidylserine phospholipids, and releasable cloaking agents configured to mask the phosphatidylserine phospholipids prior to binding of the target moieties to the target molecules and be released from the construct to expose the phosphatidylserine phospholipids upon binding of the target moieties to the target molecules. |
| FILED | Wednesday, February 09, 2022 |
| APPL NO | 18/276340 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/65 (20170801) A61K 47/6911 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108754 | BURSAC et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Nenad BURSAC (Durham, North Carolina); Hung NGUYEN (Durham, North Carolina); Tianyu WU (Durham, North Carolina) |
| ABSTRACT | Provided herein are compositions and methods for treating cardiac conditions and other diseases. In particular, the disclosure provides compositions and methods for the delivery of sodium channels. The compositions are particularly suitable in gene therapy applications and for cardiac tissue patch implantations. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/768810 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108755 | BARRETT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Lindy BARRETT (Cambridge, Massachusetts); Sara G. SUSCO (Cambridge, Massachusetts) |
| ABSTRACT | The invention features compositions and methods for treating developmental, neurodevelopmental (e.g., Fragile X syndrome (FXS)) or Down syndrome (DS) or neurodegenerative disorders (e.g., Alzheimer's disease (AD)) by increasing expression of Fragile X Mental Retardation Protein (FMRP) in patients having such disorders. |
| FILED | Friday, September 22, 2023 |
| APPL NO | 18/472864 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108758 | KASPAR |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian KASPAR (Columbus, Ohio) |
| ABSTRACT | The invention relates to compositions, compounds, methods, and uses for the treatment of amyotrophic lateral sclerosis. In particular, the invention relates to compounds, compositions, methods, and uses for the treatment of amyotrophic lateral sclerosis by increasing the expression of the MHC class I molecule, HLA-F, in motor neurons of the patient. |
| FILED | Monday, October 09, 2023 |
| APPL NO | 18/483090 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) A61K 48/0058 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240108764 — 3E8.scFv.Cys-IR800 Conjugate Targeting TAG-72 in an Orthotopic colorectal cancer model
| US 20240108764 | Tweedle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael F. Tweedle (Bexley, Ohio); Li Gong (Columbus, Ohio) |
| ABSTRACT | Disclosed are compositions are anti-TAG-72 imaging agents and methods of their use. |
| FILED | Thursday, November 30, 2023 |
| APPL NO | 18/524613 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 51/0459 (20130101) Original (OR) Class Peptides C07K 16/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108855 | ROSERO |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | German Antonio ROSERO (Bogotá, Colombia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | German Antonio ROSERO (Bogotá, Colombia) |
| ABSTRACT | The present disclosure is directed to devices, systems, and methods for percutaneous applications and/or uses of negative pressure therapy (NPT). Specifically, a novel catheter (e.g., a percutaneous drainage catheter) and a suction apparatus and/or system (e.g., a vacuum system) is disclosed. The novel catheter may include one or more sponges for absorbing one or more fluids from the body cavity of a subject or patient. Further, the suction apparatus and/or system may be configured to apply NPT. In at least one embodiment, negative pressure is applied through the catheter and/or the one or more sponges, thereby allowing fluids (e.g., abscesses, exudate, harmful material, infections material and/or infections agents, etc.) to be collected, drained, and/or otherwise removed from the body cavity of a subject or patient. |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/239016 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0021 (20130101) A61M 25/0082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108869 | Aran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kiana Aran (Berkeley, California); Jacobo Paredes (Berkeley, California); Niren Murthy (Berkeley, California); Dorian Liepmann (Lafayette, California); Kunwoo Lee (Albany, California) |
| ABSTRACT | Provided are active agent delivery devices configured to deliver an active agent formulation into or through a mucosal layer in a subject. The active agent delivery devices include a power reservoir configured to eject the active agent formulation at a pressure sufficient to deliver the active agent formulation into or through a mucosal layer in a subject. Methods of using the subject active agent delivery devices are also provided. |
| FILED | Thursday, November 30, 2023 |
| APPL NO | 18/525612 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 39/0005 (20130101) A61K 2039/542 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/00 (20130101) A61M 31/002 (20130101) Original (OR) Class A61M 2202/064 (20130101) A61M 2205/36 (20130101) A61M 2205/3324 (20130101) A61M 2205/3334 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108910 | Sharma |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amol Sharma (Evans, Georgia) |
| ABSTRACT | Systems and methods for neuromodulation therapy with repetitive magnetic stimulation of paraspinal regions have been developed for the treatment and prevention of gastroparesis. The methods identify a minimal electromagnetic intensity threshold required to elicit a motor response of 10 μV at a preferred location within the mid-thoracic region of a subject, and then deliver repetitive magnetic stimulation to the subject at a maximum 150% of the threshold value. Typically, the methods administer about 1,200 stimulations in groups of about 300 pulses having a frequency of about 1 Hz, with a rest period of about 5 minutes between pulses. Typically, the methods repeat the stimuli about twice a day for a period of around 5 days. |
| FILED | Monday, October 02, 2023 |
| APPL NO | 18/479645 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2/02 (20130101) A61N 2/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108932 | Mohieldin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire); Mary Hitchcock Memorial Hospital, for itself and on behalf of Dartmouth Hitchcock Clinic (Lebanon, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Suehayla Mohieldin (Bethesda, Maryland); Ryan J. Halter (Lyme, New Hampshire); John A. Batsis (Chapel Hill, North Carolina); Colin Minor (Southport, North Carolina); Curtis Lee Petersen (Portland, Oregon) |
| ABSTRACT | Devices and methods are disclosed for remote clinical monitoring performance of exercises using a smart resistance exercise device including a resistance band, a first handle connected to a first end of the resistance band and a second handle connected to a second end of the resistance band, a force sensing assembly operably coupled to the resistance band, and a local receiving device communicatively coupled to the force sensing assembly. The force sensing assembly of the device includes a housing, and a force sensor disposed in the housing and operatively connected to the resistance band to measure a force exerted on the resistance band. The force sensing assembly also includes a processing and communication module communicatively coupled to the force sensor to receive measurements of the force sensor and communicatively coupled to the local receiving device to transmit the measurements to the local receiving device. |
| FILED | Monday, April 10, 2023 |
| APPL NO | 18/297999 |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/00043 (20130101) Original (OR) Class A63B 2220/51 (20130101) A63B 2220/58 (20130101) A63B 2220/833 (20130101) A63B 2225/20 (20130101) A63B 2225/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109000 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Qiyong Peter Liu (Newton, Massachusetts); Herman E. Snyder (W. Lafayette, Indiana); Kyle D. Erickson (Melrose, Massachusetts); Evan P. Ordway (Salem, Massachusetts); William J. Merritt (Danvers, Massachusetts); Richard Meehan (Caragh Co, Ireland); Robert R. Andrews (Norfolk, Massachusetts); Clair Strohl (Emmaus, Pennsylvania); Jihae Sohn (Salem, Massachusetts) |
| ABSTRACT | The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A). |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/945125 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/16 (20130101) Separation B01D 1/18 (20130101) Original (OR) Class B01D 1/0082 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109071 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Baebies, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | Baebies, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Daniel Wu (Durham, North Carolina); Rainer Ng (Durham, North Carolina); Greg Smith (Durham, North Carolina); Vijay Srinivasan (Durham, North Carolina); Vamsee Pamula (Durham, North Carolina) |
| ABSTRACT | A method of thermal cycling a droplet, including providing a droplet actuator with heaters establishing a first thermal zone and second thermal zone in a substantially oil-filled droplet operations gap; a thermal cycling path comprising droplet operations electrodes comprising a first droplet operations electrode in the first thermal zone and a second droplet operations electrode in the second thermal zone, wherein the first and second droplet operations electrodes are within 5 mm of each other; a first temperature at the first droplet operations electrode and a second temperature at the second droplet operations electrode, wherein the first and second temperatures differ by at least about 10° C.; and using the droplet operations electrodes, transporting the droplet in a cycling pattern for multiple cycles along the thermal cycling path between the first droplet operations electrode and the second droplet operations electrode. Cartridges and systems are also provided. |
| FILED | Friday, December 01, 2023 |
| APPL NO | 18/526477 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502792 (20130101) B01L 7/525 (20130101) Original (OR) Class B01L 2200/16 (20130101) B01L 2300/0636 (20130101) B01L 2300/0663 (20130101) B01L 2300/1805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109832 | YU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jin-Quan YU (San Diego, California); Zhe ZHUANG (San Diego, California) |
| ABSTRACT | Disclosed herein is a process for achieving a palladium-catalyzed cyclative C(sp3)-H/C(sp2)-H coupling reaction using a native free carboxylic acid as a directing group, an amino acid ligand, and oxidant. The process is useful for synthesizing a range of biologically important scaffolds, including tetralins, chromanes, and indanes. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 18/252655 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 29/149 (20130101) C07C 51/353 (20130101) Original (OR) Class C07C 67/08 (20130101) C07C 2602/08 (20170501) C07C 2602/10 (20170501) C07C 2603/26 (20170501) Heterocyclic Compounds C07D 311/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109843 | SAFO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia); KING ABDULAZIZ UNIVERSITY (Jeddah, Saudi Arabia); THE CHILDREN'S HOSPITAL OF PHILADELPHIA (CHOP) (Philadelphia, Pennsylvania); IllExcor Therapeutics, LLC (Richmond, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Martin SAFO (Richmond, Virginia); Yan ZHANG (Glen Allen, Virginia); Piyusha Pradeep PAGARE (Richmond, Virginia); Guoyan XU (Henrico, Virginia); Mohini GHATGE (Glen Allen, Virginia); Jurgen VENITZ (Richmond, Virginia); Osheiza ABDULMALIK (Wynnewood, Pennsylvania); Andrew FLEISCHMAN (Richmond, Virginia); David LIGHT (Richmond, Virginia); Moustafa EL-ARABY (Jeddah, Saudi Arabia); Abdelsattar OMAR (Jeddah, Saudi Arabia) |
| ABSTRACT | Compounds and methods for preventing and/or treating one or more symptoms of sickle cell diseases (SCD) by administering at least one of the compounds are provided. The compounds are chemically modified to increase bioavailability and activity, e.g., so that the compounds prevent adhesion and sickling of red blood cells (RBCs). |
| FILED | Friday, November 03, 2023 |
| APPL NO | 18/501244 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) Heterocyclic Compounds C07D 213/79 (20130101) C07D 213/80 (20130101) Original (OR) Class C07D 401/04 (20130101) C07D 409/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109845 | Shokat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevan M. Shokat (San Francisco, California); Daniel Gentile (Darien, Connecticut); Steven Moss (San Francisco, California) |
| ABSTRACT | Disclosed herein, inter alia, are compositions and methods for modulating Ras and treating cancer. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/194410 |
| CURRENT CPC | Heterocyclic Compounds C07D 231/14 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) C12N 9/96 (20130101) Enzymes C12Y 306/05002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109852 | Tillekeratne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Toledo (Toledo, Ohio) |
| ASSIGNEE(S) | The University of Toledo (Toledo, Ohio) |
| INVENTOR(S) | Viranga Tillekeratne (Toledo, Ohio); Endri Karaj (Toledo, Ohio); Shaimaa Sindi (Toledo, Ohio); William Taylor (Toledo, Ohio) |
| ABSTRACT | Hybrid molecules having pharmacophores of a ferrotoptosis inducer and an HDAC inhibitor, as well as ferroptosis inducers and HDAC inhibitors, and methods of making and using the same, are described. |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/238687 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 277/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109859 | FENG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Pinghui FENG (Los Angeles, California); Chao ZHANG (Los Angeles, California); Jun ZHAO (Los Angeles, California); Biancha ESPINOSA (Los Angeles, California); Chao QIN (Los Angeles, California); Ali SAVAS (Los Angeles, California); Youliang RAO (Los Angeles, California); Ting-Yu WANG (Los Angeles, California) |
| ABSTRACT | The invention relates to antiviral compounds, compositions comprising antiviral compounds, and methods of use. In particular, the antiviral compounds are cytidine triphosphate synthetase 1 (CTPS1) inhibitors that are effective in treating and/or preventing viral infection and in particular, SARS-CoV-2 infection and/or COVID-19 disease. |
| FILED | Tuesday, February 01, 2022 |
| APPL NO | 18/263582 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/485 (20130101) A61K 9/2013 (20130101) A61K 9/2018 (20130101) A61K 9/2027 (20130101) A61K 9/2054 (20130101) A61K 9/2059 (20130101) A61K 9/4858 (20130101) A61K 9/4866 (20130101) A61K 47/10 (20130101) A61K 47/12 (20130101) A61K 47/14 (20130101) A61K 47/18 (20130101) A61K 47/26 (20130101) A61K 47/32 (20130101) A61K 47/38 (20130101) A61K 47/44 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Acyclic or Carbocyclic Compounds C07C 233/65 (20130101) C07C 233/75 (20130101) C07C 233/76 (20130101) Heterocyclic Compounds C07D 233/88 (20130101) C07D 239/94 (20130101) C07D 333/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109866 | HAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Crinetics Pharmaceuticals, Inc. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sangdon HAN (San Diego, California); Yunfei ZHU (San Diego, California); Sun Hee KIM (San Diego, California); Jian ZHAO (San Diego, California); Shimiao WANG (San Diego, California) |
| ABSTRACT | Described herein are compounds that are melanocortin subtype-2 receptor (MC2R) modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of MC2R activity. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/327466 |
| CURRENT CPC | Heterocyclic Compounds C07D 295/04 (20130101) C07D 401/10 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 407/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109872 | Georg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Ingrid Gunda Georg (Minneapolis, Minnesota); Narsihmulu Cheryala (Minneapolis, Minnesota) |
| ABSTRACT | The invention provides a compound of formula (I): or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof, wherein R1-R6 have any of the values described in the specification, as well as compositions comprising a compound of formula (I). The compounds are useful as contraceptive agents. |
| FILED | Friday, August 11, 2023 |
| APPL NO | 18/233090 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/16 (20180101) Heterocyclic Compounds C07D 405/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109883 | REMISZEWSKI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Evrys Bio, LLC (Doylestown, Pennsylvania) |
| ASSIGNEE(S) | Evrys Bio, LLC (Doylestown, Pennsylvania) |
| INVENTOR(S) | STACY REMISZEWSKI (Township of Washington, New Jersey); LILLIAN W. CHIANG (Princeton, New Jersey); FRANK KAYSER (San Francisco, California); SARAH JOCELYN FINK (Arlington, Massachusetts) |
| ABSTRACT | Novel thiazole- and/or isoquinoline-containing compounds are presented that are useful for treating cancers as well as treating and/or preventing viral infections. Methods of treating and/or preventing broad-spectrum viral infections are also presented. These compounds have been shown to inhibit HCMV, influenza virus, and coronavirus replication in cell-based assays. |
| FILED | Thursday, December 30, 2021 |
| APPL NO | 18/270288 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 31/22 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 413/14 (20130101) C07D 417/04 (20130101) C07D 417/14 (20130101) Original (OR) Class C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109892 | TAINER et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); BIOVENTURES, LLC (Little Rock, Arkansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John A. TAINER (Houston, Texas); Zamal AHMED (Sugarland, Texas); Darin E. JONES (Little Rock, Arkansas); Davide MOIANI (Houston, Texas); Chris Arlen BROSEY (Houston, Texas) |
| ABSTRACT | The present disclosure provides compounds of Formula (Ia) and Formula (Ib) and the pharmaceutically acceptable salts and solvates thereof, wherein A1, A2, R1, R2, R3, and R4 are defined as set forth in the specification. The present disclosure also provides the use of compounds of Formula (Ia) or Formula (Ib) to treat a coronavirus infection in a subject. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 18/262682 |
| CURRENT CPC | Heterocyclic Compounds C07D 473/08 (20130101) C07D 473/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109906 | Tavares et al. |
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| FUNDED BY |
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| APPLICANT(S) | G1 Therapeutics, inc. (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | G1 Therapeutics, Inc. (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Francis X. Tavares (Durham, North Carolina); Jay C. Strum (Hillsborough, North Carolina) |
| ABSTRACT | Compounds of Formulae I, II or III, and pharmaceutically acceptable salts thereof, are useful as CDK inhibitors. |
| FILED | Monday, March 13, 2023 |
| APPL NO | 18/120806 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/499 (20130101) A61K 31/527 (20130101) Heterocyclic Compounds C07D 487/14 (20130101) Original (OR) Class C07D 487/20 (20130101) C07D 498/14 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109933 | CESARMAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Ethel CESARMAN (Jersey City, New Jersey); Utthara NAYAR (Boston, Massachusetts); J. David WARREN (New York, New York); Jouliana SADEK (Roosevelt Island, None) |
| ABSTRACT | The present disclosure is directed to novel nucleoside analog compounds and methods for treating diseases characterized by high expression levels of adenosine kinase (ADK). |
| FILED | Thursday, November 30, 2023 |
| APPL NO | 18/525031 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/16 (20130101) Original (OR) Class C07H 19/20 (20130101) C07H 19/167 (20130101) C07H 19/213 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5011 (20130101) G01N 2333/912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109934 | HERGENROTHER et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Paul J. HERGENROTHER (Champaign, Illinois); Martin GARCIA CHAVEZ (Urbana, Illinois) |
| ABSTRACT | Novel Fusidic Acid (FA) based compounds that have equivalent potency against clinical isolates of Staphylococcus aureus (S. aureus) and Enterococcus faecium (E. faecium) as well as an improved resistance profile in vitro when compared to FA. Importantly, the new compounds display efficacy against a FA-resistant strain of Staphylococcus aureus in a soft-tissue murine infection model. This disclosure delineates the structural features of FA necessary for potent antibiotic activity and demonstrates that the resistance profile can be improved for this scaffold and target. |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 18/261373 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Steroids C07J 13/007 (20130101) Original (OR) Class C07J 41/0055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109938 | Aslanidi et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INCORPORATED (GAINESVILLE, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (GAINESVILLE, Florida) |
| INVENTOR(S) | George Vladimirovich Aslanidi (Gainesville, Florida); Kim M. Van Vliet (Gainesville, Florida); Mavis Agbandje-McKenna (Gainesville, Florida); Arun Srivastava (Gainesville, Florida) |
| ABSTRACT | Provided herein are modified recombinant adeno-associated virus (rAAV) capsid proteins, such as modified rAAV1, rAAV5, and rAAV6 capsid proteins, rAAV particles comprising such capsid proteins, nucleic acid molecules encoding such capsid proteins, as well as compositions, kits and methods of use thereof. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/164942 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/861 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109945 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia); GLYCOSENSORS AND DIAGNOSTICS, LLC (Athens, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Loretta Yang (San Diego, California); Shengcheng Wu (Athens, Georgia); Robert J. Woods (Athens, Georgia); Christian Gerner-Smidt (Bogart, Georgia); Lu Meng (Watkinsville, Georgia); Shaza Abnouf (Athens, Georgia) |
| ABSTRACT | An asparagine-linked glycan (N-glycan) detection reagent is provided that utilizes Fbs variants engineered from mouse Fbs proteins, wherein the Fbs variants bind specifically to N-glycosylated peptides and proteins and not to non-glycosylated peptides and proteins, including wherein the Fbs variants bind to N-glycosylated peptides and proteins and not to corresponding non-glycosylated versions of the same peptides and proteins. Compositions and methods for developing and using N-glycosylation-specific analytical, diagnostic, and therapeutic tools are provided. |
| FILED | Friday, September 01, 2023 |
| APPL NO | 18/241459 |
| CURRENT CPC | Separation B01D 15/3804 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/3274 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109948 | Palmenberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ann Carol Palmenberg (Madison, Wisconsin); Kelly Watters (Madison, Wisconsin) |
| ABSTRACT | The present invention provides soluble truncated peptides of CDHR3, recombinant variants thereof and methods of making these peptides. The present invention also provide methods of inhibiting rhinovirus C infection and an in vitro assay for screening for anti-viral agents against rhinovirus C. |
| FILED | Tuesday, April 25, 2023 |
| APPL NO | 18/306911 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109953 | Goldberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Ira J. Goldberg (New York, New York); Ainara González Cabodevilla (Brooklyn, New York); M. Mahmood Hussain (Woodbury, New York) |
| ABSTRACT | The present disclosure provides polypeptides comprising an N-terminal portion(s) of Apolipoprotein B100 (ApoB100), or functional derivatives thereof, particularly polypeptides may be capable of, e.g., inhibiting scavenger receptor-B1 (SR-B1) and/or activin receptor-like kinase 1 (ALK1). Further provided are related polynucleotides, vectors, and pharmaceutical compositions. Methods for blocking endothelial cell uptake and/or transcytosis of lipoproteins comprising chylomicrons, low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), and/or lipoprotein (a) (Lp(a)) and treating atherosclerosis using the polypeptides and/or pharmaceutical compositions are also provided. |
| FILED | Wednesday, May 10, 2023 |
| APPL NO | 18/195473 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Peptides C07K 14/775 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109955 | LI et al. |
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| FUNDED BY |
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| APPLICANT(S) | ModeX Therapeutics, Inc. (Natick, Massachusetts); The United States of America, As Represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Juan LI (Boston, Massachusetts); Chi-Jen WEI (Weston, Massachusetts); Ronnie R. WEI (Weston, Massachusetts); Zhi-Yong YANG (Newton Center, Massachusetts); John R. MASCOLA (Rockville, Maryland); Gary J. NABEL (Delray Beach, Florida); John MISASI (Bethesda, Maryland); Amarendra PEGU (Bethesda, Maryland); Lingshu WANG (Bethesda, Maryland); Tongqing ZHOU (Bethesda, Maryland); Misook CHOE (Bethesda, Maryland); Olamide K. OLONINIYI (Bethesda, Maryland); Bingchun ZHAO (Bethesda, Maryland); Yi ZHANG (Bethesda, Maryland); Eun Sung YANG (Bethesda, Maryland); Man CHEN (Bethesda, Maryland); Kwanyee LEUNG (Bethesda, Maryland); Wei SHI (Bethesda, Maryland); Nancy J. SULLIVAN (Bethesda, Maryland); Peter D. KWONG (Bethesda, Maryland); Richard A. KOUP (Bethesda, Maryland); Barney S. GRAHAM (Smyrna, Georgia); Peng HE (Natick, Massachusetts) |
| ABSTRACT | Disclosed are antigen binding polypeptides and antigen binding polypeptide complexes (e.g., antibodies and antigen binding fragments thereof) having certain structural and/or functional features. Also disclosed are polynucleotides and vectors encoding such polypeptides and polypeptide complexes; host cells, pharmaceutical compositions and kits containing such polypeptides and polypeptide complexes; and methods of using such polypeptides and polypeptide complexes. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345478 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/1003 (20230801) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/92 (20130101) C07K 2317/522 (20130101) C07K 2317/524 (20130101) C07K 2317/526 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109956 | SOK et al. |
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| FUNDED BY |
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| APPLICANT(S) | International AIDS Vaccine Initiative (New York, New York); The Scripps Research Institute (La Jolla, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Devin SOK (New York, New York); Dennis R. BURTON (La Jolla, California); Vaughn V. SMIDER (La Jolla, California); Ian WILSON (La Jolla, California); Michael CRISCITIELLO (College Station, Texas); Waithaka MWANGI (College Station, Texas) |
| ABSTRACT | The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab′)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/470044 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/162 (20130101) C07K 16/1063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109967 | MASON et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); VETIGENICS LLC (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicola J. MASON (Philadelphia, Pennsylvania); Donald L. SIEGEL (Lansdale, Pennsylvania); Nicholas CHESTER (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to canine antibodies, binding polypeptides, and scFvs specific for canine cytotoxic T lymphocyte associated protein 4 (CTLA-4). |
| FILED | Friday, October 20, 2023 |
| APPL NO | 18/491182 |
| CURRENT CPC | Peptides C07K 16/2818 (20130101) Original (OR) Class C07K 2317/20 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109973 | Khalil et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York); Tri-Institutional Therapeutics Discovery Institute, Inc. (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Danny Nejad Khalil (New York, New York); Taha Merghoub (Jersey City, New Jersey); Jedd D. Wolchok (New York, New York); Isabell Schulze (New York, New York); Ivo C. Lorenz (New York, New York) |
| ABSTRACT | The present invention provides various CD40 binding molecules (including, but not limited to, antibodies), compositions comprising such CD40 binding molecules, and methods of using such CD40 binding molecules and compositions, for example for CD40-mediated activation of cells, such as antigen presenting cells. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/267992 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2878 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 2333/70578 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110017 | Hudson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Hudson (Pittsburgh, Pennsylvania); Thomas Hinton (Pittsburgh, Pennsylvania); Adam Feinberg (Pittsburgh, Pennsylvania); Andrew Lee (Pittsburgh, Pennsylvania) |
| ABSTRACT | This document describes a process of producing gel microparticles, which are consistent in size and morphology. Through the process of coacervation, large volumes of gel microparticle slurry can be produced by scaling up reactor vessel size. Particles can be repeatedly dehydrated and rehydrated in accordance to their environment, allowing for the storage of particles in a non-solvent such as ethanol. Gel slurries exhibit a Bingham plastic behavior in which the slurry behaves as a solid at shear stresses that are below a critical value. Upon reaching the critical shear stress, the slurry undergoes a rapid decrease in viscosity and behaves as a liquid. The rheological behavior of these slurries can be adjusted by changing the compaction processes such as centrifugation force to alter the yield-stress. The narrower distribution and reduced size of these particles allows for an increase in FRESH printing fidelity. |
| FILED | Friday, May 12, 2023 |
| APPL NO | 18/196884 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/40 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110154 | METELITSA et al. |
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| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Leonid S. METELITSA (Sugar Land, Texas); Ho NGAI (Houston, Texas) |
| ABSTRACT | The present disclosure relates to methods and compositions related to Natural Killer T cells that are engineered to harbor an expression construct that encodes an activator of the Wnt signaling pathway. Activation by expression of Wnt signaling activators or the addition of exogenous activators promotes NKT expansion over the course of multiple tumor cell challenges and improves long term tumor control in vitro. The present disclosure further includes NKT cells, populations, and methods to prepare them, that are engineered to express exogenous activators of Wnt signaling combined with chimeric antigen receptors (CARs) for therapeutic use. |
| FILED | Monday, February 07, 2022 |
| APPL NO | 18/276164 |
| CURRENT CPC | Peptides C07K 14/7051 (20130101) C07K 14/70578 (20130101) C07K 16/2803 (20130101) C07K 16/3084 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) Original (OR) Class C12N 2501/415 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110156 | Colas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandre Romain Colas (La Jolla, California); Mark Mercola (Los Altos, California); Wesley Lawrence McKeithan (Palo Alto, California); Michael Shenghan Yu (San Diego, California) |
| ABSTRACT | This disclosure relates to cardiogenic mesoderm formation regulators and methods of use thereof, e.g., generating a multipotent cardiovascular progenitor cell by overexpressing Id1, Id2, Id3, Id4, Evx1, and/or Grrp1 in a stem cell. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/474821 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class C12N 2506/02 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110159 | INGBER et al. |
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| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Donald E. INGBER (Cambridge, Massachusetts); Hyun Jung Kim (Cambridge, Massachusetts) |
| ABSTRACT | The embodiments of the invention described herein relate to systems and methods for culturing and/or maintaining intestinal cells, tissues and/or organoids in vitro. The cells, tissues and/or organoids cultured according to the methods and systems described herein can mimic or reproduce natural intestinal epithelial structures and behavior as well as support co-culture of intestinal microflora. |
| FILED | Monday, December 11, 2023 |
| APPL NO | 18/535216 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/08 (20130101) C12M 23/20 (20130101) C12M 23/26 (20130101) C12M 23/34 (20130101) C12M 23/38 (20130101) C12M 25/02 (20130101) C12M 27/02 (20130101) C12M 29/04 (20130101) C12M 29/06 (20130101) C12M 35/04 (20130101) C12M 35/08 (20130101) C12M 41/12 (20130101) C12M 41/26 (20130101) C12M 41/40 (20130101) C12M 41/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/20 (20130101) C12N 5/068 (20130101) C12N 5/0679 (20130101) C12N 5/0696 (20130101) C12N 5/0697 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110160 | SHI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | PEI-YONG SHI (Galveston, Texas); XUPING XIE (Galveston, Texas); XIANWEN ZHANG (Galveston, Texas) |
| ABSTRACT | Certain embodiments are directed to a trans-complementation system, system components, and method of using the same for SARS-CoV-2 that can be performed at BSL-2 laboratories for COVID-19 research and countermeasure development. The system thus can be used by researchers in industry, academia, and government laboratories who lack access to BSL-3 facility. This approach also can be applied to other coronaviruses. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 18/273266 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2740/15043 (20130101) C12N 2770/20022 (20130101) C12N 2770/20051 (20130101) C12N 2830/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110165 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); David Benjamin Turitz Cox (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA. |
| FILED | Wednesday, October 04, 2023 |
| APPL NO | 18/480647 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6823 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110166 | Maianti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Juan Pablo Maianti (Cambridge, Massachusetts); David R. Liu (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are systems, compositions, and methods of introducing protective and/or loss-of-function variants of CCR5 and CCR2. Variants may be introduced using a CRISPR/Cas9-based nucleobase editor or other guide nucleotide sequence-programmable DNA binding protein domain-based fusion protein described herein. Further provided herein are compositions and methods of preventing and treating conditions related to HIV infection and progression as well as to AIDS. |
| FILED | Tuesday, October 10, 2023 |
| APPL NO | 18/484381 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 14/7158 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/78 (20130101) C12N 15/102 (20130101) C12N 15/1138 (20130101) C12N 2310/20 (20170501) C12N 2740/16062 (20130101) Enzymes C12Y 301/21 (20130101) C12Y 305/04001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110176 | YU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hua YU (Duarte, California); Yi-Jia LI (Duarte, California); Andreas HERRMANN (Duarte, California) |
| ABSTRACT | Provided herein are, inter alia, complexes useful for editing (e.g., repairing, modifying) DNA in a cell in vitro and in vivo. The complexes provided herein include a DNA editing agent bound to a phosphorothioate nucleic acid through a chemical linker. The chemical linker (e.g., disulfide linker) may be a linker that dissociates once the complex has entered the inside of the cell, thereby releasing the DNA editing agent and allowing the DNA editing agent to access and edit a cellular target sequence. The complexes provided herein exhibit high transfection efficiency and editing efficacy and therefore provide for useful therapeutic and diagnostic tools. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/999680 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/315 (20130101) C12N 2310/3513 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110183 | Wernig et al. |
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| FUNDED BY |
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| APPLICANT(S) | Gerlinde WERNIG (Woodside, California); Tristan LERBS (Redwood City, California); Lu CUL (Stanford, California); Qiwen DENG (Stanford, California); Cristabelle DE SOUZA (Stanford, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gerlinde Wernig (Woodside, California); Tristan Lerbs (Redwood City, California); Lu Cui (Stanford, California); Qiwen Deng (Stanford, California); Cristabelle De Souza (Stanford, California) |
| ABSTRACT | Methods are provided for the treatment of cancer and/or fibrosis. It is shown that there is increased CD63 expression both in lung cancer and pulmonary fibrosis, sarcoma, skin fibrosis, liver cancer and liver cirrhosis, NASH and NHFLD, and kidney fibrosis from hypertension and other etiologies. Inhibiting CD63 increases phagocytosis of lung cancer cells and lung fibroblasts; and can eliminates tumor cells and pathogenic fibrosis. |
| FILED | Tuesday, December 21, 2021 |
| APPL NO | 18/266790 |
| CURRENT CPC | Peptides C07K 16/2896 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110190 | BARASH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Yoseph BARASH (Wynnewood, Pennsylvania); David Sheng Ming LEE (Philadelphia, Pennsylvania); Louis R. GHANEM (Villanova, Pennsylvania); Nicholas J. HAND (Glenside, Pennsylvania) |
| ABSTRACT | Compositions and methods for treating fibrosis using oligonucleotide-based therapies are provided. These therapies can be used to increase expression of Bone morphogenetic protein receptor type II (BMPR2) via inhibition of upstream Open Reading Frames, thereby reducing vasoconstriction, vascular remodeling, and formation of fibrosis, particularly pulmonary arterial fibrosis related in patients in need thereof. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 18/264885 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/3231 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110202 | Jakymiw et al. |
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| FUNDED BY |
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| APPLICANT(S) | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Jakymiw (Charleston, South Carolina); Charles Holjencin (Summerville, South Carolina) |
| ABSTRACT | The present invention is generally related to compositions comprising and methods of using an optimized peptide delivery system for delivery of an agent into a desired cell. In certain aspects, the agent is a bioactive agent and the methods comprise the treatment or prevention of one or more disease or disorder. |
| FILED | Monday, October 04, 2021 |
| APPL NO | 18/247519 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110203 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Jonathan Strecker (Cambridge, Massachusetts); Guilhem Faure (Cambridge, Massachusetts) |
| ABSTRACT | The present application provides systems, methods and compositions used for targeted gene modification, targeted insertion, perturbation of gene transcripts, nucleic acid editing. Novel nucleic acid targeting systems comprise components of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems and transposable elements. Specifically, the disclosure provides an engineered composition comprising: a programmable DNA-binding protein and two or more Tn7-like transposition proteins, wherein at least one of the Tn7-like transposition proteins is connected to the DNA-binding protein or otherwise capable of forming a complex with the DNA-binding protein, wherein the DNA-binding protein comprising a Cas protein including a Cas12k protein, and wherein two or more Tn7-like transposition proteins consisting of TnsB, TnsC, and TniQ. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 18/270854 |
| CURRENT CPC | Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2800/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110216 | Shepherd |
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| FUNDED BY |
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| APPLICANT(S) | ZuChem, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Micah Douglas Shepherd (Melrose, Massachusetts) |
| ABSTRACT | The invention provides compositions and methods for the production of TDP-deoxysugars. |
| FILED | Tuesday, June 06, 2023 |
| APPL NO | 18/329744 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) A61K 35/66 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/88 (20130101) C12N 9/90 (20130101) C12N 9/1029 (20130101) C12N 9/1096 (20130101) C12N 9/1241 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/18 (20130101) C12P 19/60 (20130101) Original (OR) Class Enzymes C12Y 101/01049 (20130101) C12Y 206/01 (20130101) C12Y 207/07024 (20130101) C12Y 402/01046 (20130101) C12Y 501/03013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110222 | Stengel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alida Biosciences Inc. (San Diego, California) |
| ASSIGNEE(S) | Alida Biosciences Inc. (San Diego, California) |
| INVENTOR(S) | Gudrun Stengel (San Diego, California); Byron Purse (San Diego, California); Yu-Hsien Hwang-Fu (San Diego, California); Jerome Santos (San Diego, California) |
| ABSTRACT | Provided herein are compositions and methods for the multiplexed profiling of RNA and DNA modifications across transcriptomes and genomes, respectively. The methods combine molecular recognition of non-canonical features (e.g., base modifications, backbone modifications, lesions, and/or structural elements) of a target nucleic acid with a step of writing the information from this recognition event into the neighboring genetic sequence of the target nucleic acid using a barcode. The resultant barcoded nucleic acids are then converted into sequencing libraries and read by DNA/RNA sequencing methods. This step reveals the sequence of the barcode, which is correlated with the non-canonical feature in the target nucleic acid(s). The high throughput profiling methods described herein allow for localization of one or more modifications in a target nucleic acid. The methods also allow for identification of the nature and location of several or all DNA/RNA modifications in parallel. |
| FILED | Monday, October 02, 2023 |
| APPL NO | 18/479622 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110226 | Seelig et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (London, United Kingdom); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Tuesday, December 12, 2023 |
| APPL NO | 18/536721 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110227 | Seelig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (London, United Kingdom); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Tuesday, December 12, 2023 |
| APPL NO | 18/536766 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110231 | Singer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert H. Singer (New York, New York); Evelina Tutucci (New York, New York); Maria Vera Ugalde (New York, New York) |
| ABSTRACT | An RNA tagging system for visualization of single mRNA molecules based on a MSB-MCP system, as well as methods of use. |
| FILED | Tuesday, September 05, 2023 |
| APPL NO | 18/242217 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) Original (OR) Class C12Q 1/6897 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110238 | LIU et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yaping LIU (Cambridge, Massachusetts); Manolis KELLIS (Cambridge, Massachusetts); Viktor ADALSTEINSSON (Cambridge, Massachusetts); Zhizhuo ZHANG (Cambridge, Massachusetts) |
| ABSTRACT | As described below, disclosed herein are methods of analyzing DNA methylation in cell-free DNA (cfDNA) and genomic DNA (gDNA) from sequencing data. |
| FILED | Friday, September 08, 2023 |
| APPL NO | 18/463697 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6827 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2600/154 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/10 (20190201) G16B 20/20 (20190201) G16B 30/00 (20190201) G16B 40/00 (20190201) G16B 40/30 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110246 | Cantley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York); Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lewis C. Cantley (New York, New York); Bryan Ngo (New York, New York); Samuel F. Bakhoum (New York, New York) |
| ABSTRACT | As described herein, chromosomal missegregations, chromosomal micromodel, cytosolic DNA, and combinations thereof are indicative of metastatic cancer. Methods and compositions are described herein that are useful for detection and treatment of patients with chromosomal instabilities such as chromosomal missegregations, chromosomal micromilei, cytosilic DNA, and combinations thereof. For example, some of the methods and compositions include use of kinesin-13 proteins such as Kif2b, MCAK/Kif2 or KIF13A. The methods and compositions can also include is of STING, ENPPI, cGAS, NF-kB transcription factor p52, NF-kB transcription factor ReIB, or any combination thereof. Methods are also described for identifying compounds that are effective for treatment of cancer, including metastic cancer. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299558 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/04 (20130101) A61K 48/0066 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) G01N 33/5011 (20130101) G01N 2400/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110251 | BASHIR et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rashid BASHIR (Champaign, Illinois); Anurup Ganguli (San Diego, California); Jongwon Lim (Savoy, Illinois); Ariana Mostafa (San Diego, California); Enrique Andres Valera Cano (Champaign, Illinois); Matthew Wester (Champaign, Illinois); Jacob Berger (San Diego, California) |
| ABSTRACT | Described herein are systems and methods which utilize an array of wells to rapidly detect target analytes from whole blood samples, even at very low concentrations. The provided systems and methods dry the blood sample to ensure a fluidic network forms in one or more dry blood sample islands and liquid with reagents useful for detecting nucleic acid sequences from a target analyte, including by amplification reactions that are bi-phasic because of the interaction between the solid dried blood sample phase and the liquid phases, including liquid having reagents that are able to fluidically and diffusively exchange with the fluidic network within the dried blood sample phase. |
| FILED | Monday, September 25, 2023 |
| APPL NO | 18/372576 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1003 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6895 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110748 | Andrews et al. |
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| FUNDED BY |
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| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Robert R. Andrews (Norfolk, Massachusetts); Herman E. Snyder (W. Lafayette, Indiana); William J. Merritt (Danvers, Massachusetts); Evan P. Ordway (Salem, Massachusetts); Clair Strohl (Emmaus, Pennsylvania); Russell Barron (Boston, Massachusetts) |
| ABSTRACT | The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/096945 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/16 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110832 | Fantini et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sergio Fantini (Winchester, Massachusetts); Giles Blaney (Somerville, Massachusetts); Angelo Sassaroli (Arlington, Massachusetts) |
| ABSTRACT | A self-calibrating hybrid spectrophotometer comprises a receptacle for receiving the cuvette, first and second optodes that are configured to permit light to enter the cuvette, third and fourth optodes that are configured to permit light to leave the cuvette, and a controller that is configured to control delivery of light to one of the first and second optodes. Light entering one of the first and second optodes is received at the third and fourth optodes after having interacted with the turbid sample along different paths having different lengths. Measurements made at the third and fourth optodes in response to having illuminated both the first and second source optodes provide two slopes of optical transmittance as a function of path length. The spectrophotometer uses these slopes to identify a slope that is indicative of the absorption coefficient and the reduced scattering coefficient of the sample. |
| FILED | Monday, February 07, 2022 |
| APPL NO | 18/276300 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/51 (20130101) G01N 21/0303 (20130101) G01N 21/3103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110852 | LIOTTA et al. |
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| FUNDED BY |
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| APPLICANT(S) | GEORGE MASON RESEARCH FOUNDATION, INC. (Fairfax, Virginia) |
| ASSIGNEE(S) | GEORGE MASON RESEARCH FOUNDATION, INC. (Fairfax, Virginia) |
| INVENTOR(S) | Lance LIOTTA (Bethesda, Maryland); Virginia ESPINA (Rockville, Maryland); Nitin AGRAWAL (Fairfax, Virginia); Alessandra Luchini KUNKEL (Burke, Virginia) |
| ABSTRACT | Compositions and methods for the simulataneous capture and release using micropattern surfaces for tissue and cell microdissection. In one example, a patterned thermoplastic film has a first surface and a plurality of projections attached to and extending outwardly from the first surface. The projections form a pattern on the thermoplastic film. |
| FILED | Friday, September 01, 2023 |
| APPL NO | 18/241790 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2813 (20130101) Original (OR) Class G01N 2001/284 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110925 | GYORGYPAL et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aron GYORGYPAL (New Brunswick, New Jersey); Shishir P.S. CHUNDAWAT (New Brunswick, New Jersey) |
| ABSTRACT | At least some embodiments disclosed here may be directed to design and implementation of a novel PAT tool for real-time (or near real-time) online N-glycosylation analysis through the use of sequential injection analysis (SIA) coupled with liquid chromatography; rapid and robust N-glycosylation monitoring during N-glycosylated protein (e.g., monoclonal antibody) bioprocessing enabled by instant, sensitive labeling chemistry; and systems thereof. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/375243 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/08 (20130101) G01N 33/582 (20130101) G01N 33/6854 (20130101) Original (OR) Class G01N 2030/085 (20130101) G01N 2440/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110927 | Krolewski |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrzej Krolewski (Needham, Massachusetts) |
| ABSTRACT | The invention provides methods (e.g., in vitro methods) for identifying subjects at risk of renal decline and/or progression to end stage renal disease (ESRD). Also included are diagnostic and prognostic tools using markers (e.g., protein biomarkers) that may be used to identify subjects who are at risk of developing ESRD. |
| FILED | Thursday, February 02, 2023 |
| APPL NO | 18/163780 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112755 | Zhuang et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaowei Zhuang (Cambridge, Massachusetts); Jeffrey R. Moffitt (Cambridge, Massachusetts); Junjie George Hao (Cambridge, Massachusetts); Tian Lu (Cambridge, Massachusetts) |
| ABSTRACT | The present invention generally relates to systems and methods for imaging or determining nucleic acids or other desired targets, for instance, within cells or tissues. In one aspect, a sample is exposed to a plurality of nucleic acid probes that are determined within the sample. In some cases, however, background fluorescence or off-target binding may make it more difficult to determine properly bound nucleic acid probes. Accordingly, other components of the samples that may be contributing to the background, such as proteins, lipids, and/or other non-targets, may be “cleared” from the sample to improve determination. However, in certain embodiments, nucleic acids or other desired targets may be prevented from also being cleared, e.g., using polymers or gels within the sample. Other aspects are generally directed to compositions or kits involving such systems, methods of using such systems, or the like. |
| FILED | Monday, May 01, 2023 |
| APPL NO | 18/310477 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6806 (20130101) C12Q 1/6837 (20130101) C12Q 1/6841 (20130101) C12Q 2537/143 (20130101) C12Q 2543/10 (20130101) C12Q 2563/107 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112806 | Iacoviello et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ICAHN School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | ICAHN School of Medicine at Mount Sinai (New York, New York) |
| INVENTOR(S) | Brian M. Iacoviello (New York, New York); Dennis Charney (New York, New York) |
| ABSTRACT | The present disclosure relates to systems and methods for accessing a data structure including a subject identifier identifying a subject and a subject connectivity value derived from at least one of a scan or test provided to the subject, the subject connectivity value representing a magnitude of a connection associated with at least one sub-processing region of a nervous system of the subject; comparing the subject connectivity value to a connectivity threshold value to determine a classification of the subject; determining that the subject connectivity value exceeds the connectivity threshold value, storing in the data structure, an association between the subject identifier and a first classification value corresponding to a first classification or determining that the subject connectivity value is less than the connectivity threshold value, and storing in the data structure, an association between the subject identifier and a second classification value corresponding to a second classification. |
| FILED | Monday, December 11, 2023 |
| APPL NO | 18/535430 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240108220 | Hu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fu-Ming Hu (Ellicott City, Maryland); Lynn G. Stansbury (Seattle, Washington); Colin F. Mackenzie (Pasadena, Maryland); Thomas M. Scalea (Baltimore, Maryland); Deborah M. Stein (Owings Mills, Maryland); Shiming Yang (Halethorpe, Maryland) |
| ABSTRACT | A method and apparatus for monitoring collection of subject condition data is provided. The method includes receiving a value of a parameter of subject condition data and a value of a sample time, for each of a plurality of sample times. The method also includes storing the subject condition data in a data structure including a first field for holding data indicating a current sample time and a second field for holding data indicating the value of the parameter. The method also includes determining a time gap defined by a duration between the current sample time and a most recent sample time and determining whether the time gap exceeds a time gap threshold and causing an apparatus to perform remedial action. A method for presenting the subject condition data on a display is also provided. |
| FILED | Tuesday, April 04, 2023 |
| APPL NO | 18/295373 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/0008 (20130101) A61B 5/0022 (20130101) Original (OR) Class A61B 5/1113 (20130101) A61B 5/02055 (20130101) A61B 5/02405 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 10/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108709 | Super et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael Super (Lexington, Massachusetts); Edward J. Doherty (Mansfield, Massachusetts); Mark Joseph Cartwright (West Newton, Massachusetts); Des White (Oxford, Massachusetts); Alexander Stafford (Revere, Massachusetts); Omar Abdel-Rahman Ali (Oakland, California); Amanda Graveline (Boston, Massachusetts); Donald E. Ingber (Boston, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Benjamin Seiler (Boston, Massachusetts) |
| ABSTRACT | The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a pathogen in a subject having a pathogen infection, methods of increasing the surviving rate of a subject having a pathogen infection, methods of reducing the level of pain associated with a pathogen infection, and methods of reducing the level of distress associated with a pathogen infection in a subject in need thereof. Novel scaffold compositions and opsonin-bound or lectin-bound pathogen compositions, and uses thereof, are also provided herein. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/186588 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/025 (20130101) A61K 39/0258 (20130101) Original (OR) Class A61K 2039/6093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108969 | Church et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by The Secretary of the Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua Q. Church (Vicksburg, Mississippi); Megan E. Gonzalez (Vicksburg, Mississippi); James E. Richards (Vicksburg, Mississippi); Richard C. Salter (Vicksburg, Mississippi); Maria A. Seale (Clinton, Mississippi); Alicia I. Ruvinsky (Madison, Mississippi) |
| ABSTRACT | The invention relates to a game simulating research and development of a product. The game may comprise a central board, function cards, form cards, a player board and HR Meeple. The central board may comprise an endless outside track. The game may comprise three phases. A concept phase may involve: creating a product requirements document; recoding the product requirements document; collecting starting resources; building an initial team; and assigning initial tasking. A development phase may comprise: following turn and round rules; completing player actions; and assigning HR units to a facility. A prototyping phase wherein a final product is made. |
| FILED | Thursday, September 29, 2022 |
| APPL NO | 17/956745 |
| CURRENT CPC | Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 1/04 (20130101) A63F 3/00072 (20130101) Original (OR) Class A63F 13/822 (20140902) A63F 2001/0483 (20130101) A63F 2003/00066 (20130101) A63F 2003/00996 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109067 | McFarland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kirsty A. McFarland (Melrose, Massachusetts); Charles A. Lissandrello (Natick, Massachusetts); Andrew P. Magyar (Acton, Massachusetts); Erin Rosenberger (Quincy, Massachusetts) |
| ABSTRACT | Miniaturized DNA microarrays are described to be used in conjunction with microfluidic channels or microcentrifuge tubes and microcentrifuge filters to reduce sample size, incubation time and to increase overall binding efficiency. |
| FILED | Tuesday, November 28, 2023 |
| APPL NO | 18/520883 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50853 (20130101) Original (OR) Class B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 7/00 (20130101) B01L 2200/16 (20130101) B01L 2200/0689 (20130101) B01L 2300/044 (20130101) B01L 2300/168 (20130101) B01L 2300/0636 (20130101) Centrifuges B04B 3/00 (20130101) B04B 5/0414 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) C12Q 1/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109112 | Shivpuri |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rajiv Shivpuri (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are devices and methods related to friction stir extrusion. In particular, the present disclosure relates to die assemblies configured for use in a forward friction stir extrusion system and die assemblies configured for use in a backward friction stir extrusion system. The die assemblies in the forward and backward friction stir extrusion systems can include a die piece comprising a sloped surface, wherein at least a portion of the sloped surface is a textured surface. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/478381 |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 25/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109383 | Flory et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRATT and MILLER ENGINEERING and FABRICATION, LLC (New Hudson, Michigan) |
| ASSIGNEE(S) | Pratt and Miller Engineering and Fabrication, LLC (New Hudson, Michigan) |
| INVENTOR(S) | Kenneth J. Flory (West Bloomfield, Michigan); Jesper Slattengren (Ann Arbor, Michigan); Guido Francesco Ritelli (Farmington Hills, Michigan) |
| ABSTRACT | A hydraulic suspension system for a motor vehicle having at least a pair of road engaging wheels. The suspension system includes, a hydraulic cylinder coupled with the each of the pair of road engaging wheels, the hydraulic cylinder defining a cap end volume and a rod end volume separated by a piston. A hydraulic supply circuit for the hydraulic cylinder includes, a high pressure hydraulic source, a low pressure hydraulic drain, a pair of hydraulic sub circuits each coupled to one of the hydraulic cylinder cap and rod end volumes. Each hydraulic sub circuit includes, a proportional supply flow valve coupled with the high pressure hydraulic source and one of the cylinder volumes, a return flow control proportional valve coupled with the low pressure hydraulic drain and the one cylinder volume, and an accumulator coupled to the associated hydraulic cylinder volume through an accumulator fill control proportional valve. |
| FILED | Wednesday, March 29, 2023 |
| APPL NO | 18/127911 |
| CURRENT CPC | Vehicle Suspension Arrangements B60G 11/265 (20130101) Original (OR) Class B60G 17/056 (20130101) B60G 2202/154 (20130101) B60G 2202/413 (20130101) B60G 2202/414 (20130101) B60G 2202/416 (20130101) B60G 2300/07 (20130101) B60G 2500/114 (20130101) B60G 2600/182 (20130101) B60G 2800/912 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109778 | Thevamaran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramathasan Thevamaran (Madison, Wisconsin); Abhishek Gupta (Madison, Wisconsin); Komal Chawla (Madison, Wisconsin); Bhanugoban Maheswaran (Madison, Wisconsin) |
| ABSTRACT | Carbon nanotube foams are provided which comprise tubes substantially aligned longitudinally in a first direction, wherein: each tube defines an outer wall and an inner wall, and each tube comprises an entangled bundle of carbon nanotubes substantially aligned longitudinally in the first direction; and tubes in at least a subset of the tubes are positioned with respect to each other to form one or more first hexagonal units, wherein each first hexagonal unit comprises first-hexagonal-unit tubes, wherein the first-hexagonal-unit tubes comprise six peripheral first-hexagonal-unit tubes and a central first-hexagonal-unit tube, wherein the six peripheral first-hexagonal-unit tubes surround the central first-hexagonal-unit tube in a juxtaposed, hexagonal configuration. Articles of manufacture, e.g., helmets, comprising the foams are also provided which are configured to cover at least a portion of an object, e.g., a human head, and to attenuate an external force acting on the object, including external forces originating from oblique impacts. |
| FILED | Friday, August 11, 2023 |
| APPL NO | 18/448297 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/158 (20170801) Original (OR) Class C01B 2202/08 (20130101) C01B 2202/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109808 | Srubar, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Prometheus Materials Inc. (Longmont, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wilfred V. Srubar, III (Boulder, Colorado); Sherri Cook (Boulder, Colorado); Jeffrey Cameron (Erie, Colorado); Mija Hubler (Boulder, Colorado); Stephen Bell (Berthoud, Colorado); Linfei Li (Superior, Colorado) |
| ABSTRACT | Disclosed herein is a transportable bio-cement comprising a desiccated microorganism package; where the microorganism package comprises one or more microorganisms; a first binder, where the first binder is produced by the microorganism; and where the microorganism has protected itself by a layer of the first binder; where the transportable bio-cement is devoid of moisture. Disclosed herein too is a method of manufacturing a transportable dry composition comprising blending together a microorganism package; a nutrient; and a liquid; activating the microorganism package to produce a first binder; subjecting the microorganism package to desiccation to form a transportable bio-cement; and blending the transportable bio-cement with an aggregate to form a bio-concrete; where the aggregate comprises a substrate, a second binder, and a liquid. |
| FILED | Monday, September 18, 2023 |
| APPL NO | 18/468812 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 12/00 (20130101) Original (OR) Class C04B 16/00 (20130101) C04B 26/026 (20130101) C04B 2103/0001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109837 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); Zhenning Yu (Beavercreek, Ohio) |
| ABSTRACT | A family of low-molecular-weight, main-chain thermotropic liquid-crystalline polyimides (TLC-PI) that are crosslinkable is disclosed. These all-aromatic TLC-PI are derived from (i) wholly aromatic and flexible diamine monomers, in which the linkage between the two aniline-ends contains a relatively high heat-tolerant but flexible chain constituted by two or more units of 1,4-phenoxy or 1,3-phenoxy or in combinations of both. Processes of making and using such all-aromatic TLC-PI is also provided. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299375 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 213/06 (20130101) C07C 217/90 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/1071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109848 | McQuade et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ODH IP Corp. (NEW YORK, New York) |
| ASSIGNEE(S) | ODH IP Corp. (NEW YORK, New York) |
| INVENTOR(S) | D. Tyler McQuade (Rockville, Maryland); Luke Rogers (Rockville, Maryland); Josef Maier (Rockville, Maryland); Julian Chesterman (Rockville, Maryland); Esther Chen (Rockville, Maryland); Saad Bux (Rockville, Maryland); Brenden Herrera (Rockville, Maryland); Loan Truong (Rockville, Maryland); Melanie Pachter (Rockville, Maryland) |
| ABSTRACT | Described herein are methods for the preparation of imidazobenzodiazepines such as midazolam and its intermediates. The processes are capable of using continuous flow chemistry and systems. |
| FILED | Wednesday, September 13, 2023 |
| APPL NO | 18/466730 |
| CURRENT CPC | Heterocyclic Compounds C07D 243/28 (20130101) Original (OR) Class C07D 243/30 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109873 | Bender et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aaron M. Bender (Spring Hill, Tennessee); Matthew Spock (Nashville, Tennessee); Melissa A. Korkmaz-Vaisys (Nashville, Tennessee); Cori A. Malinky (Nashville, Tennessee); P. Jeffrey Conn (Nashville, Tennessee); Craig W. Lindsley (Brentwood, Tennessee) |
| ABSTRACT | Disclosed herein are compounds of formula (III) useful as antagonists of the muscarinic acetylcholine receptor M4 (mAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating neurodegenerative disorders using the compounds and compositions. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 18/258351 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Heterocyclic Compounds C07D 405/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109936 | Aldrich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Jane V. Aldrich (Gainesville, Florida); Jay Patrick McLaughlin (Gainesville, Florida); Dmitry Yakovlev (Gainesville, Florida) |
| ABSTRACT | The disclosure relates to macrocyclic peptides and pharmaceutical compositions thereof. The disclosure further relates to pharmaceutical compositions for modulating opioid receptor activity. The macrocyclic tetrapeptides provided herein are useful in treating diseases or disorders relating to the activity of one or more opioid receptors, such as neurological disorders. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 18/268037 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/04 (20180101) Peptides C07K 5/126 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109954 | Alter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Galit Alter (Winchester, Massachusetts); Richard Lu (Somerville, Massachusetts) |
| ABSTRACT | Described herein are Fe-enhanced antibodies and methods of use thereof. Also described are Fe-enhanced antibodies to treat Ebola virus infection. |
| FILED | Tuesday, February 01, 2022 |
| APPL NO | 18/274641 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/14 (20130101) C07K 2317/55 (20130101) C07K 2317/524 (20130101) C07K 2317/526 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110011 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); Zhenning Yu (Beavercreek, Ohio); Bingqian Zheng (Miamisburg, Ohio); Hilmar Koerner (Beavercreek, Ohio) |
| ABSTRACT | Applicants disclose a family of low-molecular-weight, main-chain thermotropic liquid-crystalline polyimides (TLC-PI) that are thermally crosslinkable and processes of making and using same. Such materials provide flexibility advantage when modifying ink materials to meet varying processing conditions in additive manufacturing of devices and components that require high-temperature polymers. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299090 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/1067 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110012 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); Zhenning Yu (Beavercreek, Ohio) |
| ABSTRACT | Crosslinkable, low-molecular-weight, main-chain thermotropic liquid-crystalline co-polyimides derived from the polycondensation of (i) liquid-crystallinity-enabling, wholly aromatic and flexible diamine monomers, in which the linkage between the two aniline-ends contains a relatively high heat-tolerant but flexible chain constituted by multiple phenoxy (MP) moieties, i.e., two or more units of 1,4-phenoxy or 1,3-phenoxy or in combinations of both. Such polyimides allow the modification of ink materials to meet varying processing conditions in additive manufacturing of devices and components that require high-temperature polymers. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299096 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/1071 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110098 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); Zhenning Yu (Beavercreek, Ohio); Bingqian Zheng (Miamisburg, Ohio); Hilmar Koerner (Beavercreek, Ohio) |
| ABSTRACT | A family of low-molecular-weight, main-chain thermotropic liquid-crystalline co-polyimides (TLC-CoPI) that are crosslinkable, and based on a unique, liquid-crystallinity (LC)-enabling diamine, namely, 1,3-bis[4-(4′-aminophenoxy)cumyl]benzene (BACB) and two or more mesogenic dianhydrides, at least one of which is a diphthalic dianhydride (DPA) that contains one or more thermally reactive and crosslinkable moieties similar to that of phenylethynyl (PE) is disclosed. Processes of making and using such low-molecular-weight, main-chain thermotropic liquid-crystalline co-polyimides are also provided. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299100 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/3823 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110246 | Cantley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York); Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lewis C. Cantley (New York, New York); Bryan Ngo (New York, New York); Samuel F. Bakhoum (New York, New York) |
| ABSTRACT | As described herein, chromosomal missegregations, chromosomal micromodel, cytosolic DNA, and combinations thereof are indicative of metastatic cancer. Methods and compositions are described herein that are useful for detection and treatment of patients with chromosomal instabilities such as chromosomal missegregations, chromosomal micromilei, cytosilic DNA, and combinations thereof. For example, some of the methods and compositions include use of kinesin-13 proteins such as Kif2b, MCAK/Kif2 or KIF13A. The methods and compositions can also include is of STING, ENPPI, cGAS, NF-kB transcription factor p52, NF-kB transcription factor ReIB, or any combination thereof. Methods are also described for identifying compounds that are effective for treatment of cancer, including metastic cancer. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299558 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/04 (20130101) A61K 48/0066 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) G01N 33/5011 (20130101) G01N 2400/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110354 | Smith |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by The Secretary of the Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David L Smith (Vicksburg, Mississippi) |
| ABSTRACT | An apparatus for guiding fish through a body of water having a water flow includes one or more hydrofoil element oriented in the body of water to produce an asymmetric flow field that has a fast, low turbulent flow on one side of the element and a slow, high turbulent flow on the other side of the element. Positively rheotactic fish have a preference for one side versus the other and so are guided in a desired direction. Systems and method that utilize the apparatus can be used to guide fish away from infrastructure such as dams, locks, levees, flood weirs, and other diversion points. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/957306 |
| CURRENT CPC | Hydraulic Engineering E02B 8/085 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110841 | Hirsch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Brandon Hirsch (Bloomington, Indiana); Matthew Keller (Bloomington, Indiana); Stephen Becker (Loogootee, Indiana); Michael A. Samp (Champaign, Illinois) |
| ABSTRACT | Provided are methods and associated apparatus for determining the integrity of a hermetically sealed electronic component. The method and associated apparatus includes the use of an evacuation chamber configured to placing the hermetically sealed electronic component within. The evacuation chamber is then evacuated of atmosphere to then determine an atmospheric pressure evacuation relationship or curve occurring inside the chamber that is, in turn, used to determine the integrity of the hermetically sealed electronic component. Further aspects may include evacuating the chamber through a mass spectrometer coupled to the evacuation chamber for chemical analysis of at least one of the evacuated atmosphere for making further determinations of the integrity of the hermetically sealed electronic component. |
| FILED | Wednesday, October 04, 2023 |
| APPL NO | 18/376579 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/205 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240111027 | Britton |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Matthew C. Britton (Rancho Palos Verdes, California) |
| ABSTRACT | Analyzing electro-optical imagery from a telescope observing one or more satellites includes capturing one or more images of a plurality of stars and the one or more satellites, and sequentially or randomly selecting each one of a plurality of diagonal lines of pixels in the one or more images. The plurality of diagonal lines of pixels represent one of the plurality of stars in the one or more images. Additionally, a moving average filter is applied to the selected one of the plurality of diagonal lines of pixels to find a location of one of the plurality of start on an x- and y-axis coordinate. Furthermore, the location of the one of the plurality of stars is provided in the one or more captured images to be cross referenced with angular coordinates and radiometric quantities in stellar catalogs. |
| FILED | Wednesday, September 28, 2022 |
| APPL NO | 17/936342 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/7867 (20130101) G01S 7/4816 (20130101) Original (OR) Class G01S 7/4817 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240111065 | Nelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyle Alan Nelson (San Diego, California); Stephanie Lam (San Diego, California) |
| ABSTRACT | A detector detects at least one neutron. The detector includes at least one thin absorption layer each including an absorption material for absorbing the neutron and then radioactively decaying into energetic byproducts. The detector includes at least one emission layer each including a solid scintillation material for converting the energetic byproducts into photons. The detector includes a sensor for detecting the photons. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/958030 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/20184 (20200501) G01T 1/20188 (20200501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240111346 | Dasalukunte et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Deepak Dasalukunte (Beaverton, Oregon); Amy Whitcombe (Saratoga, California); Finbarr O'Regan (Innishannon, Ireland); Conor O'Keeffe (Cork, Ireland); Sundar Krishnamurthy (Dublin, California) |
| ABSTRACT | An apparatus can include at least two circuit portions having separate power sequencer circuitry. The apparatus can further include processing circuitry configured to control at least one portion of the at least two circuit portions to operate at an initial low power level and subsequent higher power levels to full operation. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/957052 |
| CURRENT CPC | Electric Digital Data Processing G06F 1/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240111400 | Keel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul Erich Keel (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Erich Keel (Cambridge, Massachusetts); Jeffrey Huang (Lausanne, Switzerland) |
| ABSTRACT | A computer-implemented method for interacting with at least one data item obtained from at least one source utilizes computer processes responsive to a user selection of the at least one data item and include causing configuring of each of the data items into a distinct information object by extracting, from each data item, extracted data including a picture, a heading, and a link to the data item, and causing storing of data corresponding to each of the information objects in a database system. The processes further include displaying a representation of each of at least two of the information objects in the database system, the representation being in a uniform format, wherein the format includes a card, and, within the card, in uniform locations thereof, the picture, the heading, a set of indicators, and a set of graphically accessible functions. |
| FILED | Tuesday, December 12, 2023 |
| APPL NO | 18/536753 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04817 (20130101) G06F 3/04842 (20130101) Original (OR) Class G06F 16/22 (20190101) G06F 16/29 (20190101) G06F 16/258 (20190101) G06F 16/9535 (20190101) G06F 16/9537 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 51/046 (20130101) H04L 67/10 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 707/99933 (20130101) Y10S 707/99943 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240111807 | Macker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Macker (Washington, District of Columbia); Michael lannelli (Washington, District of Columbia) |
| ABSTRACT | Systems and methods are provided for a hypergraph representation and transformation process enabling the cogeneration and analysis of multiple system attributes alongside system node relationships within real world data models. Embodiments of the present disclosure allow for the cogeneration of attribute embeddings, along with node embeddings, within a single, graph-based data set model. Embodiments of the present disclosure provide a higher level of accuracy in problem space representation compared to conventional systems and methods and help to reveal more complex relationships in real world problems. |
| FILED | Saturday, September 30, 2023 |
| APPL NO | 18/375504 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/906 (20190101) G06F 16/9024 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240111872 | Gilton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York); BAE Systems Controls Inc. (Endicortt, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York); BAE Systems Controls Inc. (Endicott, New York) |
| INVENTOR(S) | Jeffrey S. Gilton (Cincinnati, Ohio); Matthew B. Pfenninger (Cincinnati, Ohio); Douglas R. Nichols (Kentwood, Michigan); Russell Seidel (Endicott, New York) |
| ABSTRACT | A method for initializing an engine control system of an aircraft may include authenticating a boot loader, authenticating a manifest in response to authentication of the boot loader wherein the manifest contains hashes of one or more software components, and in response to authentication of the manifest, loading a first set of software components from among the one or more software components onto a non-transitory computer-readable medium, calculating a hash of each software component of the first set of software components, authenticating the first set of software components by comparing the calculated hash of each software component of the first set of software components to the hash of a corresponding software component in the manifest, and executing the first set of software components in response to authentication of the one or more software components. Devices and systems are also provided for initializing an engine control system of an aircraft. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/956940 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/44 (20130101) G06F 21/575 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112022 | Bycroft |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamen Paul Bycroft (Los Angeles, California) |
| ABSTRACT | Systems and methods are provided for adjusting confidence models that are used to generate augmented prediction output or to otherwise determine a degree of confidence in a prediction output. A machine learning model may be trained to generate prediction output (e.g., classification output or regression output), and a confidence model of training data support for predictions of the machine learning model may be generated. The data modeled by the confidence model may initially be the feature space representation of the training data. The confidence model may be a malleable confidence model in the sense that when the machine learning model is used by an inference service to evaluate operational data, the prediction output and/or operational data input may be used to adjust the confidence model based on observed changes and data. |
| FILED | Tuesday, October 04, 2022 |
| APPL NO | 17/960019 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6256 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112489 | Mai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adrian Mai (San Diego, California); Douglas Seth Lange (San Diego, California) |
| ABSTRACT | A method for extracting data from a single-layer raster navigational chart (RNC) comprising: using a computer vision algorithm to extract color, text and symbol data from the RNC, storing the color, text, and symbol data in a database, and building an RNC data vector based solely on the color, text, and symbol data of the RNC, wherein the RNC data vector identifies geographical features shown in the RNC and a location of the geographical features' corresponding pixels in the RNC; and drawing a region of interest on the navigational chart based on user input and the RNC data vector, wherein a perimeter of the region of interest is georeferenced with latitude and longitude information. |
| FILED | Tuesday, October 04, 2022 |
| APPL NO | 17/960000 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 30/147 (20220101) G06V 30/422 (20220101) Original (OR) Class G06V 30/1801 (20220101) G06V 30/18105 (20220101) G06V 30/19013 (20220101) G06V 30/19107 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112756 | Seaman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Charles Stark DraperLaboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laura Seaman (Cambridge, Massachusetts) |
| ABSTRACT | A system and processes enable determination of the genetic location of a sequence of interest including markers of genetic engineering. More specifically, a system and/or a series of processes are used independently or together to allow assembly, annotation, and visualization of genetic elements of interest (GEI) as well as their genetic surroundings from sequencing data. This can enable users to quickly and efficiently review and interpret the results so they can understand what GEIs are present in a sample, where they are, and their surroundings. It can be used to enrich sequences of interest or with sequences that have not been enriched and can help answer research questions such as understanding the on and off target effects of genetic engineering or discovery of novel gene homologs. |
| FILED | Friday, July 28, 2023 |
| APPL NO | 18/360957 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/20 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113337 | XU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kang XU (Potomac, Maryland); Chunsheng WANG (Silver Spring, Maryland); Chongyin YANG (College Park, Maryland) |
| ABSTRACT | The present invention is directed to aqueous solid state electrolytes that comprise a fluoride additive to stabilize the interface between the anode and aqueous electrolyte. The present invention is also directed to methods of making the solid state electrolyte materials and methods of using the solid state electrolyte materials in batteries and other electrochemical technologies. |
| FILED | Wednesday, November 29, 2023 |
| APPL NO | 18/523704 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/134 (20130101) H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/667 (20130101) H01M 4/5835 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113783 | Adleman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Richard Adleman (San Diego, California); Sanja Zlatanovic (San Diego, California); David Chao (San Diego, California) |
| ABSTRACT | A radio frequency (RF) transceiver comprising: a transmitter configured to produce a plurality of optical carriers; a multi-wavelength electro-optic modulator configured to receive the plurality of optical carriers from the transmitter, wherein the electro-optic modulator is configured to modulate each optical carrier using a same input RF signal, but with a different efficiency for each optical carrier so as to generate an arbitrary number of RF links with various efficiencies using a single modulation electrode; and a receiver designed to produce a synthesized transfer function based on a truncated Fourier Series and configured to use the synthesized transfer function to adjust intermodulation distortion response to optimize dynamic range for the transceiver's operating resolution bandwidth and noise characteristics. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/957068 |
| CURRENT CPC | Transmission H04B 10/40 (20130101) H04B 10/54 (20130101) H04B 10/2543 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113867 | Gilton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York); BAE Systems Controls Inc. (Endicott, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York); BAE Systems Controls Inc. (Endicott, New York) |
| INVENTOR(S) | Jeffrey S. Gilton (Cincinnati, Ohio); Matthew B. Pfenninger (Cincinnati, Ohio); Douglas R. Nichols (Kentwood, Michigan); Russell Seidel (Endicott, New York) |
| ABSTRACT | A distributed control system includes an electronic control unit to establish secure communication with a distributed control module. Upon determination that a previously negotiated session key is stored on the electronic control unit, the electronic control unit transmits encrypted communications with the distributed control module using the previously negotiated session key, negotiates a new session key with the distributed control module, and stores the new session key. Upon determination that the previously negotiated session key is not stored on the electronic control unit, the electronic control unit negotiates the new session key with the distributed control module. After negotiating the new session key with the distributed control module, the electronic control unit ceases transmission of unencrypted communications with the distributed control module, transmits encrypted communications with the distributed control module using the new session key, and stores the new session key. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/956939 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/085 (20130101) H04L 9/0833 (20130101) Original (OR) Class H04L 9/0841 (20130101) H04L 9/0894 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113952 | SOHA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Michael James SOHA (Chelmsford, Massachusetts); Allison Inez MANN (Highland Park, New Jersey); John Michael ZUENA (Burlington, Massachusetts) |
| ABSTRACT | Described herein are systems and methods for assessing a computing network's physical robustness to node and/or link failure during operation of the computing network. In one or more examples, the systems and methods can incorporate graph modeling and analysis techniques to assess the impact of node removal from a computing network and determine the impact that such removal has on the overall physical connectivity of the network. In one or more examples, a user or other entity can provide the system with a graph representation of a computing network, as well as specify the number of nodes to be removed (i.e., to simulate failure) to test the connectivity of the network. The system using these inputs can determine a worst-case scenario operating condition based on the inputs provided by the user, and can also assess the “network merit” which can represent a user-programmable definition that can represent a plurality desired types of connectivity. |
| FILED | Thursday, December 07, 2023 |
| APPL NO | 18/532586 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/14 (20130101) H04L 43/045 (20130101) H04L 43/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240114010 | HARTLEY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Eden Prairie, Minnesota) |
| INVENTOR(S) | Timothy HARTLEY (Eden Prairie, Minnesota); Deborah Charan (Eden Prairie, Minnesota); Ranga S. RAMANUJAN (Eden Prairie, Minnesota) |
| ABSTRACT | Disclosed herein are embodiments of systems, methods, and products comprising a computing device, which provides Efficient Data-In-Transit Protection Techniques for Handheld Devices (EDITH) to protect data-in-transit. An end user device (EUD) may generate a multicast data packet. The EDITH module of the EUD encapsulates the data packet in a GRE packet and directs the GRE packet to a unicast destination address of an EDITH Multicast Router included in an infrastructure. The EDITH module on the EUD double compresses and double encrypts the GRE packet. The EDITH module on the infrastructure decrypts and decompresses the double compressed and double encrypted GRE packet to recreate the GRE packet. The EDITH module on the infrastructure decapsulates the GRE packet to derive the original multicast data packet, and distributes the original multicast data packet to the multiple group member based on the multicast destination address included in the original multicast data packet. |
| FILED | Monday, March 06, 2023 |
| APPL NO | 18/117768 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/602 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 45/16 (20130101) H04L 47/2441 (20130101) H04L 49/201 (20130101) H04L 63/0272 (20130101) H04L 63/0428 (20130101) Original (OR) Class H04L 69/22 (20130101) Wireless Communication Networks H04W 4/06 (20130101) H04W 12/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240114653 | Wattier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by The Secretary of the Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua D. Wattier (Champaign, Illinois); Nathaniel J. Bidner (Champaign, Illinois) |
| ABSTRACT | In one embodiment, an enclosure device for a printed circuit board (PCB) comprises: an enclosure wall structure including therein a heater exchanger, a pipe to direct a cooling liquid through the heat exchanger, and a ducting to direct a gas through the heat exchanger to be cooled by the cooling liquid; and a PCB space adjacent to a portion of the enclosure wall structure for receiving the PCB. The ducting includes a downstream duct disposed downstream of the heat exchanger and extending through the portion of the enclosure wall structure adjacent to the PCB space to direct the cooled gas to the portion of the enclosure wall structure adjacent to the PCB space. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/957230 |
| CURRENT CPC | Electric Digital Data Processing G06F 1/181 (20130101) G06F 1/206 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0201 (20130101) H05K 7/2039 (20130101) H05K 7/20154 (20130101) H05K 7/20272 (20130101) Original (OR) Class H05K 2201/064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240114706 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Biwu Ma (Tallahassee, Florida); Qingquan He (Tallahassee, Florida) |
| ABSTRACT | Methods of passivating a surface. The methods may include providing a mixture including a liquid and a derivative of quinacridone, applying the mixture to a first surface of a film that includes a metal halide perovskite, and annealing the film for a time and a temperature effective to convert the derivative of quinacridone to quinacridone. Composite materials and electronic devices also are provided. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/351601 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/005 (20130101) Organic electric solid-state devices H10K 30/10 (20230201) H10K 30/88 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240114707 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Biwu Ma (Tallahassee, Florida); Qingquan He (Tallahassee, Florida) |
| ABSTRACT | Methods of passivating a surface. The methods may include providing a mixture including a liquid and a derivative of quinacridone, applying the mixture to a first surface of a film that includes a metal halide perovskite, and annealing the film for a time and a temperature effective to convert the derivative of quinacridone to quinacridone. Composite materials and electronic devices also are provided. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/351603 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/005 (20130101) Organic electric solid-state devices H10K 30/10 (20230201) H10K 30/88 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240114764 | Dou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Letian Dou (West Lafayette, Indiana); Blake Peter Finkenauer (West Lafayette, Indiana) |
| ABSTRACT | A perovskite-polymer composite comprising a perovskite and a polymer, wherein the polymer has a structural unit comprising a thiourea (—HN(C═S)NH—) fragment and a (—R1—O—R2—) fragment, wherein R1 and R2 are each independently a C1-C6 alkyl or a cycloalkyl linker; a mechanically robust and self-healable solar cell comprising same; and a method of making same. |
| FILED | Friday, December 01, 2023 |
| APPL NO | 18/527201 |
| CURRENT CPC | Organic electric solid-state devices H10K 30/10 (20230201) H10K 85/10 (20230201) Original (OR) Class H10K 85/40 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240108780 | VILLA-ALEMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | ELIEL VILLA-ALEMAN (AIKEN, South Carolina); JOHN T. BOBBITT, III (EVANS, Georgia); WENDY KUHNE (EVANS, South Carolina); MICHAEL C. MAXWELL (AIKEN, South Carolina); MATTHEW FOLSOM (AIKEN, South Carolina); CHARLES TURICK (AIKEN, South Carolina); COURTNEY BURCKHALTER (TRENTON, South Carolina); TRAVIS HUBBARD (WARRENVILLE, South Carolina); TYLER BARNES (CORDOVA, South Carolina); JOSEPH KINNEY (AIKEN, South Carolina) |
| ABSTRACT | Air purification devices are described. Devices are powered to form an electric field along an airflow path that creates a plasma for destruction of pathogens carried through the device. Devices can be single-user, portable devices for purification of air flow to and/or from a single user. |
| FILED | Thursday, September 29, 2022 |
| APPL NO | 17/955882 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 9/22 (20130101) Original (OR) Class A61L 9/032 (20130101) A61L 2209/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108999 | MILLER |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jacob Miller (Sudbury, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob MILLER (Sudbury, Massachusetts) |
| ABSTRACT | Methods and Apparatus for Rejecting Moisture from a Desiccant Solution A method of rejecting moisture from a working desiccant solution and regenerating the working desiccant solution comprises receiving a stream of desiccant solution containing moisture to be rejected (12), and diluting at least a portion of the stream of desiccant solution containing moisture to be rejected, to form a diluted stream (38). The method further comprises passing the diluted stream (38) through an evaporator (24) for evaporating the moisture from the diluted stream; concentrating the desiccant solution, thereby to regenerate the desiccant solution; and outputting a regenerated stream of desiccant solution (14). |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/374712 |
| CURRENT CPC | Separation B01D 1/0011 (20130101) B01D 1/0082 (20130101) Original (OR) Class B01D 53/1412 (20130101) B01D 53/1425 (20130101) B01D 2257/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109001 | Pearson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Connor Daniel Pearson (Overland Park, Kansas); Sabrina Marie Wells Torres (Lee’s Summit, Missouri) |
| ABSTRACT | Systems, apparatuses, and methods for microfluidic fluid evaporation using femtosecond laser-patterned surfaces are disclosed. A microfluidic device may comprise a femtosecond laser-patterned substrate having at least one input path and at least one output path. The femtosecond laser-patterned substrate may comprise both superhydrophobic and superhydrophilic sections. Fluid deposited at an input path may be wicked to an output path due to the surface pattern. A heating device may be provided to heat the fluid to evaporate volatiles therefrom. Vacuums and gas streams may be used to aid in volatile removal. Gas streams may add gas to the microfluidic device to react with the fluid. |
| FILED | Thursday, April 06, 2023 |
| APPL NO | 18/296863 |
| CURRENT CPC | Separation B01D 1/221 (20130101) Original (OR) Class B01D 2202/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109039 | Jassby et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | David Jassby (Los Angeles, California); Unnati Rao (Los Angeles, California); Eric Hoek (Los Angeles, California); Bongyeon Jung (Los Angeles, California) |
| ABSTRACT | A membrane desalination system includes a housing, an electrically conductive membrane disposed within the housing, wherein the electrically conductive membrane includes a porous support and an electrically conductive layer disposed on the porous support, and the electrically conductive layer includes nanostructures, and an alternating current power source connected to the electrically conductive membrane. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 18/266516 |
| CURRENT CPC | Separation B01D 65/08 (20130101) Original (OR) Class B01D 67/0079 (20130101) B01D 69/02 (20130101) B01D 69/148 (20130101) B01D 71/0212 (20220801) B01D 71/381 (20220801) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/441 (20130101) C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109040 | Darling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Seth B. Darling (Berwyn, Illinois); Zijing Xia (Chicago, Illinois) |
| ABSTRACT | A mineral membrane and method of making the same are disclosed. The mineral membrane may be made by exfoliating a mineral material to produce a membrane, and cross-linking the membrane. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/957033 |
| CURRENT CPC | Separation B01D 67/0044 (20130101) B01D 67/0069 (20130101) B01D 67/0076 (20130101) B01D 69/125 (20130101) Original (OR) Class B01D 71/027 (20130101) B01D 2323/30 (20130101) B01D 2323/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109051 | MA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shengqian MA (Tampa, Florida); Qi SUN (Tampa, Florida); Briana AGUILA (Tampa, Florida) |
| ABSTRACT | Compositions are provided for efficient uranium extraction, for example from wastewater, seawater, or other water sources. The compositions can include a functionalized porous organic polymer functionalized with one or more uranium binding moieties, e.g. having a plurality of amidoxime or amidrazone groups covalently attached thereto. The compositions can include covalent organic frameworks, porous aromatic frameworks, and various porous organic polymers, especially those having a hierarchical pore size distribution over a range of pore sizes. The compositions can have functional groups such as amidoxime or an amidrazone covalently attached thereto. The hierarchical pore size distribution can be determined based upon at least 60% of the pore sizes in the range of pore sizes having a pore volume of at least 0.01 cm3 g−1 in the pore size distribution at 77 K. Methods of making the compositions and methods of using the compositions are also provided. |
| FILED | Thursday, February 16, 2023 |
| APPL NO | 18/170463 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/267 (20130101) Original (OR) Class B01J 20/2808 (20130101) B01J 20/3085 (20130101) B01J 20/28066 (20130101) B01J 20/28071 (20130101) B01J 20/28083 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 112/34 (20130101) C08F 2810/00 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109103 | Kumar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sortera Technologies, Inc. (Markie, Indiana) |
| ASSIGNEE(S) | Sortera Technologies, Inc. (Markle, Indiana); Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Nalin Kumar (Fort Wayne, Indiana); Manuel Gerardo Garcia (Austin, Texas); Isha Kamleshbhai Maun (Arlington, Texas); Jeffrey A. Lacey (Ammon, Idaho); Lorenzo Vega Montoto (Idaho Falls, Idaho) |
| ABSTRACT | Systems and methods for classifying and sorting of dark colored and/or black-colored plastic materials utilizing a vision system or one or more sensor systems implemented with one or more medium wavelength infrared cameras whereby the captured image data is process within a machine learning system in order to identify or classify each of the materials, which may then be sorted into separate groups based on such an identification or classification. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 18/264752 |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/04 (20130101) B07C 5/34 (20130101) B07C 5/342 (20130101) B07C 5/3422 (20130101) Original (OR) Class B07C 2501/0054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109786 | PATHERIA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Eshaan S. PATHERIA (Pasadena, California); Kimberly A. ROBB (Pasadena, California) |
| ABSTRACT | Provided herein are compositions, devices, electrochemical systems, and methods relating to lithium-rich iron sulfide lithium-ion battery cathodes. In one embodiment, a composition may be characterized by formula FX1: Liw-δAlxFezS2. In some embodiments, w may be greater than or equal to 2 and less than or equal to 2.5. In some embodiments, x may be greater than 0 and less than or equal to 0.5. In some embodiments, z may be greater than 0 and less than or equal to 1. In some embodiments, δ may be greater than or equal to 0 and less than w. In some embodiments, the composition may have a net charge of 0. |
| FILED | Monday, September 18, 2023 |
| APPL NO | 18/369425 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/12 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/30 (20130101) C01P 2002/60 (20130101) C01P 2002/72 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109788 | BROW et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan Ray BROW (Denver, Colorado); Shriram SANTHANAGOPALAN (Sylvania, Ohio); Chaiwat ENGTRAKUL (Louisville, Colorado) |
| ABSTRACT | An atmospheric microplasma process is used to synthesize cathode particles in less than approximately one second. A hollow-tube reactor may be used to create cathode particles that are in the range of approximately 0.1 μm to approximately 3 μm in diameter, are at least partially crystalline, and show redox behavior expected of a transition metal oxide cathode material. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/478119 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/10 (20130101) B01J 19/087 (20130101) B01J 19/088 (20130101) B01J 19/2415 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/44 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/74 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109928 | KENT |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael S. KENT (Albuquerque, New Mexico) |
| ABSTRACT | The present invention provides for a method to convert water-insoluble lignin into water-soluble polyacid, the method comprising: (a) contacting a chelator/Fe complex with a water-insoluble lignin to produce a reaction mixture, (b) introducing an oxidizing agent to the reaction mixture, (c) incubating the reaction mixture for a suitable period of time, (d) introducing further water-insoluble lignin to the reaction mixture during step (c); (e) introducing further oxidizing agent to the reaction mixture incubating step (c); and (f) optionally repeating step (d) and/or step (e) one or more times; such that at least about 90% of the water-insoluble lignin in the reaction mixture is converted into a water-soluble polyacid by the opening of at least one aromatic ring in each water-insoluble lignin. |
| FILED | Tuesday, October 10, 2023 |
| APPL NO | 18/483617 |
| CURRENT CPC | Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 11/00 (20130101) Compounds of Unknown Constitution C07G 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110073 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cheng Zhu (Livermore, California); Eric Duoss (Dublin, California); Christopher Spadaccini (Oakland, California); Marcus A. Worsley (Hayward, California); Jianchao Ye (Tracy, California); Swetha Chandrasekaran (Dublin, California) |
| ABSTRACT | An aerogel includes a three-dimensional printed structure having printed ligaments geometrically arranged, where an average diameter of the printed ligaments is in a range of greater than 0 microns and less than 50 microns. In addition, an average distance between a center of a first of the printed ligaments and a center of a second of the printed ligaments is at least equal to the average diameter of the printed ligaments, where the first and the second of the printed ligaments are adjacent. Each printed ligament includes of a plurality of random pores, where an average diameter of the random pores is less than 50 nanometers. |
| FILED | Friday, December 01, 2023 |
| APPL NO | 18/527021 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/042 (20170501) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/03 (20130101) C09D 11/38 (20130101) Original (OR) Class C09D 11/103 (20130101) C09D 11/324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110149 | FORD et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leah Renae FORD (Medord, Massachusetts); Michael Thomas GUARNIERI (Denver, Colorado); Michael G. RESCH (Golden, Colorado); Lauren Rae MAGNUSSON (Lakewood, Colorado) |
| ABSTRACT | Disclosed herein are non-naturally occurring C. autoethanogenum adapted to electrolyzer off-gas feedstock conditions that possess increased growth rates when compared to naturally occurring naturally occurring C. autoethanogenum. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/478608 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Original (OR) Class C12N 9/0093 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/065 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/145 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110254 | Zeng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Zuotao Zeng (Woodridge, Illinois); John P. Kopasz (Bolingbrook, Illinois); Theodore R. Krause (Naperville, Illinois); Angel Yanguas-Gil (Northbrook, Illinois); Meimei Li (Willowbrook, Illinois) |
| ABSTRACT | A hydrogen-plasma rotary kiln furnace reactor and a method of reducing iron ore to iron using the same are disclosed. The hydrogen-plasma rotary kiln furnace includes a rotary kiln furnace and a hydrogen-plasma generator. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/957101 |
| CURRENT CPC | Manufacture of Iron or Steel C21B 13/08 (20130101) Original (OR) Class Furnaces, Kilns, Ovens, or Retorts in General; Open Sintering or Like Apparatus F27B 7/10 (20130101) F27B 7/3205 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 11/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110285 | Mane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Anil U. Mane (Naperville, Illinois); Jeffrey W. Elam (Elmhurst, Illinois) |
| ABSTRACT | A calorimetry sensor having a porous substrate and a temperature sensitive resistive coating. The calorimetry sensor has a known temperature coefficient of resistance. A process utilizes the known temperature coefficient of resistance and monitors changes in resistance of the calorimetry sensor to determine changes in temperature (heat) within an environment, such as during reactions within an ALD reactor. |
| FILED | Thursday, September 29, 2022 |
| APPL NO | 17/956665 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/52 (20130101) Original (OR) Class C23C 16/4408 (20130101) C23C 16/45527 (20130101) C23C 16/45555 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110292 | Curtiss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Larry A. Curtiss (Downers Grove, Illinois); Hsien-Hau Wang (Downers Grove, Illinois); Khalil Amine (Oakbrook, Illinois); Samuel Plunkett (Chicago, Illinois) |
| ABSTRACT | The present invention provides, in part, methods and processes for the production of lithium superoxide (LiO2) which is free of other lithium-oxygen compounds, as well as compositions and electrochemical cells comprising lithium superoxide (e.g., lithium superoxide that is free of other lithium-oxygen compounds). |
| FILED | Thursday, September 22, 2022 |
| APPL NO | 17/950321 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/14 (20130101) Original (OR) Class C25B 11/032 (20210101) C25B 11/043 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110835 | Bhattacharya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sumit Bhattacharya (Darien, Illinois); Cari A. Launiere (Bolingbrook, Illinois); Abdellatif M. Yacout (Naperville, Illinois) |
| ABSTRACT | A corrosion resistant coating suitable for use in harsh environments, such as for protecting a temperature probe for continuous use in the Hall-Héroult process can include at least one first layer comprising a metal boride and at least one second layer comprising a metal interposed between the substrate and the at least one metal boride layer. The coating can have a thickness of less than 10 micrometers. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/374851 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/14 (20130101) C23C 14/22 (20130101) C23C 14/067 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/02 (20130101) Original (OR) Class G01K 7/36 (20130101) G01K 11/22 (20130101) G01K 11/3206 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240111200 | Hernandez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tyler S. Hernandez (Boulder, Colorado); Michael T. Strand (Boulder, Colorado); Andrew L. Yeang (Boulder, Colorado); Michael D. McGehee (Boulder, Colorado) |
| ABSTRACT | Electrochromic “smart” windows allow control of solar and heat flux through the window without sacrificing the view. Despite such appeal, traditional technologies lack the inability to simultaneously achieve fast switching with color neutral tinting and a wide optical dynamic range at low cost. Reversible metal electrodeposition (RME) addresses the drawbacks of existing metal-oxide electrochromic technologies. Several possible RME electrolytes at various pHs with different supporting anions were studied (NO3−, SO42−, ClO4, Cl−, Br−). Acidic perchlorate electrolytes work particularly well, permitting fully reversible metal electrodeposition without harming the substrate or introducing irreversible side reactions. The perchlorate electrolyte shows promising long-term durability in terms of both cycle life and shelf-life, demonstrating 10,000 stable cycles with no evidence of electrode etching. In addition, the use of this perchlorate electrolyte widens the deposition voltage window, enabling construction of relatively large area dynamic windows that tint relatively uniformly with fast, color-neutral switching at low cost. |
| FILED | Friday, January 29, 2021 |
| APPL NO | 18/274858 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/155 (20130101) G02F 1/1506 (20130101) Original (OR) Class G02F 1/1524 (20190101) G02F 2001/1555 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112822 | LUCAS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | X-energy, LLC (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Ryan LUCAS (Arlington, Virginia); Michael SAITTA (Alexandria, Virginia); Gwennaël BEIRNAERT (Alexandria, Virginia); Martin Peter VAN STADEN (Rockville, Maryland) |
| ABSTRACT | A neutron reflector design which lowers stress in inner reflector members by supporting the inner reflector members on radially adjacent outer reflector members at the interface between the inner and outer reflector members, such that an individual inner reflector member is not supported by an inner reflector member in a layer of the reflector assembly immediately below, and the inner reflector member does not have to bear a load from an inner reflector member in a layer of the reflector assembly immediately above. The lowering of the load carried by the individual inner reflector members with this individual-member-support arrangement reduces stress-induced reflector damage with is enhanced in the high radiation flux environment adjacent to a nuclear reactor core. The inner reflector members are removable for replacement without the need to remove the outer reflector members. |
| FILED | Saturday, October 01, 2022 |
| APPL NO | 17/958363 |
| CURRENT CPC | Nuclear Reactors G21C 11/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112855 | WANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian-Ping WANG (Shoreview, Minnesota); Md MEHEDI (Minneapolis, Minnesota); YanFeng JIANG (Minneapolis, Minnesota); Bin MA (Roseville, Minnesota); Delin ZHANG (Minneapolis, Minnesota); Fan ZHANG (Minneapolis, Minnesota); Jinming LIU (Minneapolis, Minnesota) |
| ABSTRACT | The disclosure is directed to an iron-nitride material having a polycrystalline microstructure including a plurality of elongated crystallographic grains with grain boundaries, the iron-nitride material including at least one of an α″-Fe16N2 phase and a body-center-tetragonal (bct) phase comprising Fe and N. The disclosure is also directed a method producing an iron-nitride material. The method includes some combinations of preparing a raw material comprising iron, carrying out a microstructure build-up by annealing the prepared raw material at an elevated temperature and subsequently quenching the prepared raw material to produce a microstructure build-up material, annealing the microstructure build-up material, reducing the microstructure build-up material in a hydrogen environment, nitriding the reduced material to produce a nitrided material and subsequently quenching the nitrided material to a martensitic transformation temperature, stress annealing the nitrided material, and magnetic field annealing the stress-annealed material. |
| FILED | Tuesday, December 05, 2023 |
| APPL NO | 18/529331 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0622 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/03 (20130101) H01F 1/10 (20130101) H01F 41/0253 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113279 | HU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Liangbing HU (Hyattsville, Maryland); Chengwei WANG (College Park, Maryland); Eric D. WACHSMAN (Fulton, Maryland); Venkataraman THANGADURAI (Calgary, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Liangbing HU (Hyattsville, Maryland); Chengwei WANG (College Park, Maryland); Eric D. WACHSMAN (Fulton, Maryland); Venkataraman THANGADURAI (Calgary, Canada) |
| ABSTRACT | A battery cell that include sulfide cathodes are described with examples being suitable for operation at elevated temperatures. Also described are methods of making and using these battery cells. |
| FILED | Thursday, November 30, 2023 |
| APPL NO | 18/524937 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) H01M 4/134 (20130101) H01M 4/136 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113319 | PENDRAY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CUMMINS INC. (Columbus, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Robert PENDRAY (Blaine, Minnesota); Achyut PAUDEL (Columbus, Indiana); Lars Krister HENRICHSEN (Columbus, Indiana); Enrique GARCIA-TORRESOLA (Columbus, Indiana); Jinyong LUO (Columbus, Indiana) |
| ABSTRACT | A method includes providing steam to the solid oxide fuel cell stack, splitting exhaust gas from the cell stack into two portions, a first portion directed to a superheater and a second portion directed to an ejector and to a hydrogen separator. At least part of the first portion of the exhaust gas that is directed to the superheater is subsequently boiled in a boiler and then returned to the superheater. After being returned to the superheater, this part is directed to the ejector as high pressure steam so as to drive the ejector. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/478739 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 9/19 (20210101) C25B 13/07 (20210101) C25B 15/083 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/186 (20130101) Original (OR) Class H01M 8/04014 (20130101) H01M 8/04097 (20130101) H01M 8/04164 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113337 | XU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kang XU (Potomac, Maryland); Chunsheng WANG (Silver Spring, Maryland); Chongyin YANG (College Park, Maryland) |
| ABSTRACT | The present invention is directed to aqueous solid state electrolytes that comprise a fluoride additive to stabilize the interface between the anode and aqueous electrolyte. The present invention is also directed to methods of making the solid state electrolyte materials and methods of using the solid state electrolyte materials in batteries and other electrochemical technologies. |
| FILED | Wednesday, November 29, 2023 |
| APPL NO | 18/523704 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/134 (20130101) H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/667 (20130101) H01M 4/5835 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113340 | Xiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jie Xiao (Richland, Washington); Bingbin Wu (Richland, Washington); Wei Wang (West Richland, Washington); Dianying Liu (Richland, Washington); Ruozhu Feng (Richland, Washington) |
| ABSTRACT | An electrolyte composition comprising a solution comprising an active salt; and a solvent portion that comprises a first solvent and a second solvent, wherein the first solvent is a hydrofluorocarbon compound having a structure of CxHyFz, wherein x is from 4 to 10, y is from 1 to 10, z is from 5 to 20, and the z:y ratio is from 2:1 to 10:1. |
| FILED | Thursday, September 08, 2022 |
| APPL NO | 17/940799 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) H01M 4/382 (20130101) H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/587 (20130101) H01M 4/5825 (20130101) H01M 8/02 (20130101) H01M 8/188 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 10/4235 (20130101) H01M 50/105 (20210101) H01M 2004/028 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113524 | Arnold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Arnold (Berkeley, California); Shammya Saha (Knoxville, Tennessee); Ciaran Roberts (Berkeley, California); Sy-Toan Ngo (Berkeley, California); Sean Peisert (Berkeley, California); Anna Scaglione (Ithaca, New York) |
| ABSTRACT | One or more embodiments relates to a smart inverter used in a photovoltaic (PV) generation system. In one embodiment, the smart inverter includes a PV control logic device; and at least one low pass filter coupled to and in communication with the at least one PV control logic device. |
| FILED | Thursday, September 29, 2022 |
| APPL NO | 17/956310 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/18 (20130101) H02J 3/381 (20130101) Original (OR) Class H02J 2300/24 (20200101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113870 | Alshowkan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Muneer Alshowkan (Oak Ridge, Tennessee); Philip G. Evans (Clinton, Tennessee); Michael Starke (Knoxville, Tennessee); Nicholas A. Peters (Knoxville, Tennessee) |
| ABSTRACT | Systems, methods, and computer-readable programs are provided for authentication of unencrypted message(s) transmitted between two devices of a power grid over a public communications network are provided. The authentication uses a quantum-based secret key and an initialization vector generated from a quantum random number to generate a payload for a transmission packet. The quantum-based secret key is shared between the transmitting device and the receiving device. When the receiving device receives the packet, the receiving device uses the shared quantum-based secret key and the initialization vector to verify whether the payload in the packet is authentic. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/478376 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0858 (20130101) Original (OR) Class H04L 9/0869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240114773 | Correa-Baena et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Juan-Pablo Correa-Baena (Atlanta, Georgia); Mark D. Losego (Atlanta, Georgia); Andres-Felipe Castro-Mendez (Atlanta, Georgia); Selma Fairach (Atlanta, Georgia); Emily K. McGuinness (Atlanta, Georgia); Carlo Andrea Riccardo Perini (Atlanta, Georgia); Jamie P. Wooding (Atlanta, Georgia) |
| ABSTRACT | The present disclosure provides for a composition comprising a compound configured to form internal π bonds, and an inorganic material, wherein the composition is defined by a first surface opposing a second surface and a first thickness measured from the first surface to the second surface of the composition, and a method of making thereof. Further provided herein is a device comprising at least one of the compositions disclosed herein. Also disclosed herein is a photovoltaic device. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/237037 |
| CURRENT CPC | Organic electric solid-state devices H10K 30/40 (20230201) H10K 30/84 (20230201) H10K 85/50 (20230201) H10K 85/624 (20230201) H10K 85/633 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20240107947 | Borgatti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AppHarvest Technology, Inc. (Morehead, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Borgatti (Morehead, Kentucky); Ryan R. Knopf (Morehead, Kentucky); Ryan Wasserman (Morehead, Kentucky); Joshua Aaron Lessing (Morehead, Kentucky); Jason A. Chrisos (Morehead, Kentucky); Michele Pratusevich (Morehead, Kentucky); Wesley Bird (Morehead, Kentucky) |
| ABSTRACT | A collection tool comprises a drive chassis, a harvester module disposed on the drive chassis, the harvester module including a vision system configured to identify target objects, and a robotic arm including a grasper configured to collect the target objects, and a subsystem including an articulating semi-rigid catch member, the semi-rigid catch member configured to transition into a retracted state while the drive chassis is in motion and to transition into an extended state while the drive chassis is stationary and the robotic arm is in a process of collecting the target objects. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 18/553722 |
| CURRENT CPC | Harvesting; Mowing A01D 46/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108220 | Hu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fu-Ming Hu (Ellicott City, Maryland); Lynn G. Stansbury (Seattle, Washington); Colin F. Mackenzie (Pasadena, Maryland); Thomas M. Scalea (Baltimore, Maryland); Deborah M. Stein (Owings Mills, Maryland); Shiming Yang (Halethorpe, Maryland) |
| ABSTRACT | A method and apparatus for monitoring collection of subject condition data is provided. The method includes receiving a value of a parameter of subject condition data and a value of a sample time, for each of a plurality of sample times. The method also includes storing the subject condition data in a data structure including a first field for holding data indicating a current sample time and a second field for holding data indicating the value of the parameter. The method also includes determining a time gap defined by a duration between the current sample time and a most recent sample time and determining whether the time gap exceeds a time gap threshold and causing an apparatus to perform remedial action. A method for presenting the subject condition data on a display is also provided. |
| FILED | Tuesday, April 04, 2023 |
| APPL NO | 18/295373 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/0008 (20130101) A61B 5/0022 (20130101) Original (OR) Class A61B 5/1113 (20130101) A61B 5/02055 (20130101) A61B 5/02405 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 10/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108253 | Gu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zhen Gu (Los Angeles, California); Yi Zeng (Los Angeles, California) |
| ABSTRACT | A minimally invasive glucose-responsive colloidal crystal microneedle (GCC-MN) patch is disclosed for naked-eye glucose monitoring. The (GCC-MN) patch is designed with a resin or polymeric core to mechanically support a shell of glucose-responsive colloidal crystal material for glucose sensing and reporting of glucose concentrations or concentration changes. The GCC-MN patch could translate the glucose concentrations into naked-eye distinguishable color changes within about 5 min, and such glucose responsiveness is reversible. Demonstrated in a type 1 diabetic mouse model, the interstitial fluid extraction, glucose sensing, and resulting glucose-relevant color display procedures are simultaneously achieved with this GCC-MN patch. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 18/261591 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/685 (20130101) A61B 5/14532 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/28 (20130101) C08J 3/075 (20130101) C08J 2343/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240108932 | Mohieldin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire); Mary Hitchcock Memorial Hospital, for itself and on behalf of Dartmouth Hitchcock Clinic (Lebanon, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Suehayla Mohieldin (Bethesda, Maryland); Ryan J. Halter (Lyme, New Hampshire); John A. Batsis (Chapel Hill, North Carolina); Colin Minor (Southport, North Carolina); Curtis Lee Petersen (Portland, Oregon) |
| ABSTRACT | Devices and methods are disclosed for remote clinical monitoring performance of exercises using a smart resistance exercise device including a resistance band, a first handle connected to a first end of the resistance band and a second handle connected to a second end of the resistance band, a force sensing assembly operably coupled to the resistance band, and a local receiving device communicatively coupled to the force sensing assembly. The force sensing assembly of the device includes a housing, and a force sensor disposed in the housing and operatively connected to the resistance band to measure a force exerted on the resistance band. The force sensing assembly also includes a processing and communication module communicatively coupled to the force sensor to receive measurements of the force sensor and communicatively coupled to the local receiving device to transmit the measurements to the local receiving device. |
| FILED | Monday, April 10, 2023 |
| APPL NO | 18/297999 |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/00043 (20130101) Original (OR) Class A63B 2220/51 (20130101) A63B 2220/58 (20130101) A63B 2220/833 (20130101) A63B 2225/20 (20130101) A63B 2225/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109110 | Quigley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut); Joseph G. Michels (Pocono Summit, Pennsylvania); Melinda Sims (Seattle, Washington) |
| ABSTRACT | A control system for controlling extraction of landfill gas from a landfill via a gas extraction system comprising well piping, the landfill gas having a first temperature when extracted, the control system comprising: a gas composition chamber coupled to the well piping and comprising at least one sensor configured to measure one or more characteristics of a landfill gas sample in the gas composition chamber; a temperature control mechanism configured to heat the landfill gas sample in the gas composition chamber to a second temperature at least a threshold amount greater than the first temperature; and a controller configured to control the at least one sensor to measure the one or more characteristics of the landfill gas sample in the gas composition chamber when a temperature of the landfill gas sample in the gas composition chamber is at least the threshold amount greater than the first temperature. |
| FILED | Friday, December 01, 2023 |
| APPL NO | 18/526824 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109111 | Quigley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (North Potomac, Maryland) |
| ABSTRACT | A method for use by a system coupled to at least one sensor and at least one flow control mechanism of a gas extraction system, the system comprising at least one controller and configured for use in connection with a landfill gas extraction process for extraction of landfill gas from a landfill via the gas extraction system, the method comprising: using the at least one controller to perform: obtaining, based on at least one measurement made by the at least one sensor, at least one current value indicative of a selected characteristic of the landfill gas extraction process, determining, at discrete time intervals, whether the at least one current value satisfies at least one compliance criterion for the selected characteristic, and when it is determined that the at least one current value does not satisfy the at least one compliance criterion for the selected characteristic, performing a corrective action. |
| FILED | Thursday, December 14, 2023 |
| APPL NO | 18/540281 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109832 | YU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jin-Quan YU (San Diego, California); Zhe ZHUANG (San Diego, California) |
| ABSTRACT | Disclosed herein is a process for achieving a palladium-catalyzed cyclative C(sp3)-H/C(sp2)-H coupling reaction using a native free carboxylic acid as a directing group, an amino acid ligand, and oxidant. The process is useful for synthesizing a range of biologically important scaffolds, including tetralins, chromanes, and indanes. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 18/252655 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 29/149 (20130101) C07C 51/353 (20130101) Original (OR) Class C07C 67/08 (20130101) C07C 2602/08 (20170501) C07C 2602/10 (20170501) C07C 2603/26 (20170501) Heterocyclic Compounds C07D 311/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109956 | SOK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International AIDS Vaccine Initiative (New York, New York); The Scripps Research Institute (La Jolla, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Devin SOK (New York, New York); Dennis R. BURTON (La Jolla, California); Vaughn V. SMIDER (La Jolla, California); Ian WILSON (La Jolla, California); Michael CRISCITIELLO (College Station, Texas); Waithaka MWANGI (College Station, Texas) |
| ABSTRACT | The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab′)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/470044 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/162 (20130101) C07K 16/1063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110100 | Jakli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Antal Jakli (Kent, Ohio); Chenrun Feng (Kent, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Antal Jakli (Kent, Ohio); Chenrun Feng (Kent, Ohio) |
| ABSTRACT | The present invention relates to a doped ferroelectric nematic liquid crystal having a chirality-induced stabilization of the polar nematic order, improved relaxation time for electro-optical switching, and selective reflection in the visible wavelength that is reversibly tunable. The ferroelectric nematic liquid crystal is doped with a chiral dopant selected from the group benzoic acid, 4-hexyl-,4-[[(1-methylheptyl)oxy]carbonyl]phenyl ester (ZLI811) and BDH1281. |
| FILED | Wednesday, September 21, 2022 |
| APPL NO | 17/949516 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/0225 (20130101) C09K 19/584 (20130101) Original (OR) Class C09K 2019/2078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110143 | Wikswo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Kieran David Nehil-Puleo (Nashville, Tennessee); Ronald S. Reiserer (Nashville, Tennessee) |
| ABSTRACT | One aspect of the invention provides a network platform that includes a fluidic network comprising one or more pumps, and one or more valves, and a plurality of fluidic modules interconnected by the fluidic network of the one or more pumps and the one or more valves to allow controlled transfer of suspended cells, other substances, and fluids from one fluidic module to another, or self-circulation. |
| FILED | Monday, December 04, 2023 |
| APPL NO | 18/527751 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/08 (20130101) C12M 23/10 (20130101) C12M 23/12 (20130101) C12M 23/16 (20130101) C12M 23/50 (20130101) C12M 23/58 (20130101) C12M 27/02 (20130101) C12M 27/12 (20130101) C12M 29/10 (20130101) Original (OR) Class C12M 35/02 (20130101) C12M 35/04 (20130101) C12M 41/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110150 | CAMPOS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUESTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Luis M. CAMPOS (Pennington, New Jersey); Rinat MEIR (MEYER) (Modiin, Israel) |
| ABSTRACT | Exemplary embodiments of the present disclosure provides biomaterials, systems, and methods that utilize upconversion biomaterials to stimulate optogenetic cells in three-dimensional settings. Provided is a biomaterial including chromophores capable of converting low-energy light to high-energy light embedded in biocompatible materials. This technology enables more selective stimulation of optogenetic cells in three-dimensional scaffolds and has the potential to provide critical insights into cell function and disease. |
| FILED | Friday, June 02, 2023 |
| APPL NO | 18/205040 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/025 (20130101) C09K 2211/1011 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110226 | Seelig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (London, United Kingdom); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Tuesday, December 12, 2023 |
| APPL NO | 18/536721 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110227 | Seelig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Georg Seelig (Seattle, Washington); Richard Muscat (London, United Kingdom); Alexander B. Rosenberg (Seattle, Washington) |
| ABSTRACT | Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens. |
| FILED | Tuesday, December 12, 2023 |
| APPL NO | 18/536766 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110301 | Cerron Calle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gabriel Cerron Calle (Tempe, Arizona); Ana dos Santos Fajardo (Marinha Grande, Portugal); Sergio Garcia-Segura (Tempe, Arizona); Carlos M. Sanchez (Paris, France) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gabriel Cerron Calle (Tempe, Arizona); Ana dos Santos Fajardo (Marinha Grande, Portugal); Sergio Garcia-Segura (Tempe, Arizona); Carlos M. Sanchez (Paris, France) |
| ABSTRACT | A nanocomposite electrode includes a porous copper substrate, Co3O4 and/or Cu/Co(OH)x nanoparticles electrolytically deposited on the porous copper substrate. Fabricating the nanocomposite electrode includes contacting the porous copper substrate with a solution comprising cobalt, and electrodepositing the cobalt on the porous copper substrate to yield the nanocomposite electrode. Reducing nitrate to ammonia includes contacting the nanocomposite electrode with an aqueous solution comprising nitrate, and electrocatalytically reducing the nitrate to yield ammonia. |
| FILED | Tuesday, May 23, 2023 |
| APPL NO | 18/321991 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/27 (20210101) C25B 11/031 (20210101) C25B 11/061 (20210101) C25B 11/077 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110914 | Emam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shadi Emam (Boston, Massachusetts); Nian-Xiang Sun (Winchester, Massachusetts) |
| ABSTRACT | Described herein is a sensor comprising a doped silicon layer, a graphene layer on the doped silicon layer, a molecularly imprinted polymer (MIP) layer on the graphene layer, and electrodes in operative arrangement with the MIP layer and configured to provide a signal indicative of resistance. The MIP layer is derived from a MIP monomer and functional monomer. Also described herein is a detector comprising a sensor described herein as well as methods of making and using the sensors and detectors, e.g., to detect an analyte, such as a virus. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 18/260881 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/262 (20130101) B01J 20/268 (20130101) B01J 20/28035 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/126 (20130101) G01N 33/5438 (20130101) G01N 33/56983 (20130101) Original (OR) Class G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240111566 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yaohui Hu (Binghamton, New York); Kartik Gopalan (Vestal, New York) |
| ABSTRACT | Standard nested virtualization allows a hypervisor to run other hypervisors as guests, i.e. a level-0 (L0) hypervisor can run multiple level-1 (L1) hypervisors, each of which can run multiple level-2 (L2) virtual machines (VMs), with each L2 VM is restricted to run on only one L1 hypervisor. Span provides a Multi-hypervisor VM in which a single VM can simultaneously run on multiple hypervisors, which permits a VM to benefit from different services provided by multiple hypervisors that co-exist on a single physical machine. Span allows (a) the memory footprint of the VM to be shared across two hypervisors, and (b) the responsibility for CPU and I/O scheduling to be distributed among the two hypervisors. Span VMs can achieve performance comparable to traditional (single-hypervisor) nested VMs for common benchmarks. |
| FILED | Monday, December 04, 2023 |
| APPL NO | 18/528775 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) Original (OR) Class G06F 2009/4557 (20130101) G06F 2009/45579 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240111970 | Strachan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Paul Strachan (San Carlos, California); Dejan S. Milojicic (Palo Alto, California); Martin Foltin (Fort Collins, Colorado); Sai Rahul Chalamalasetti (Milpitas, California); Amit S. Sharma (Milpitas, California) |
| ABSTRACT | In some examples, a device includes a first processing core comprising a resistive memory array to perform an analog computation, and a digital processing core comprising a digital memory programmable with different values to perform different computations responsive to respective different conditions. The device further includes a controller to selectively apply input data to the first processing core and the digital processing core. |
| FILED | Monday, December 04, 2023 |
| APPL NO | 18/528086 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Hybrid Computing Arrangements G06J 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112150 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiong Yu (Beachwood, Ohio); Xudong Fan (Cleveland, Ohio) |
| ABSTRACT | Systems and methods are described for making repair decisions to improve resilience of a utility distribution network (UDN). A graph convolutional network (GCN) integrates reinforcement learning to provide an integrated model framework, in which the GCN encodes the information of the UDN, such as topology and operating characteristics. A neural network is connected to the GCN, and the framework trains the neural network to provide a recovery sequence based on the current state (e.g., a damaged state) of the UDN based one or more performance indicators. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/468009 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/20 (20130101) Original (OR) Class G06Q 10/06315 (20130101) G06Q 10/06375 (20130101) G06Q 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112399 | Ramani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karthik Ramani (West Lafayette, Indiana); Subramaniam Chidambaram (West Lafayette, Indiana); Sai Swarup Reddy (Sunnyvale, California) |
| ABSTRACT | A system and method for multi-media instruction authoring is disclosed. The multi-media instruction authoring system and method provide a unified and efficient system that supports the simultaneous creation of instructional media in AR, VR, and video-based media formats by subject matter experts. The multi-media instruction authoring system and method require only a single demonstration of the task by the subject matter expert and does not require any technical expertise of the subject matter expert. The multi-media instruction authoring system and method incorporate a 3D editing interface for free hand, in-headset interaction to create 2D videos from 3D recordings, by exploring novel virtual camera interactions. |
| FILED | Tuesday, October 03, 2023 |
| APPL NO | 18/480173 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/014 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 13/40 (20130101) G06T 17/00 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 40/11 (20220101) G06V 40/28 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112424 | Ramani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karthik Ramani (West Lafayette, Indiana); Zhengzhe Zhu (West Lafayette, Indiana); Ziyi Liu (Delaware, Ohio); Tianyi Wang (West Lafayette, Indiana) |
| ABSTRACT | An augmented reality (AR) interaction authoring system is described. The AR interaction authoring system is configured to support the real-time creation of AR applications to support AR-enhanced toys. The design of the AR interaction authoring system enables bidirectional interactions between the physical-virtual space of toys and AR. The AR interaction authoring system allows intuitive authoring of AR animations and toys actuations through programming by demonstration, while referring to the physical toy for a contextual reference. Using a visual programming interface, users can create bidirectional interactions by utilizing users' input on toys to trigger AR animations and vice versa. A plug-and-play IoT toolkit is also disclosed that includes hardware to actuate common toys. In this way, users can effortlessly integrate toys into the virtual world in an impromptu design process, without lengthy electronic prototyping. |
| FILED | Tuesday, October 03, 2023 |
| APPL NO | 18/480158 |
| CURRENT CPC | Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/63 (20140902) A63F 13/577 (20140902) A63F 13/655 (20140902) Electric Digital Data Processing G06F 3/0346 (20130101) G06F 3/04815 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Original (OR) Class G06T 2200/24 (20130101) G06T 2210/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112603 | Moehring et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OtoNexus Medical Technologies, Inc. (Bellevue, Washington) |
| ASSIGNEE(S) | OtoNexus Medical Technologies, Inc. (Bellevue, Washington) |
| INVENTOR(S) | Mark A. Moehring (Seattle, Washington); George Gates (Seattle, Washington); Charlie Corredor (Seattle, Washington); Chad J. McDonald (Seattle, Washington) |
| ABSTRACT | Disclosed herein is a device for modeling properties of an ear. The device includes an artificial tympanic membrane and a housing coupled to the artificial tympanic membrane. The housing defines an interior portion coupled to an interior surface of the artificial tympanic membrane. The interior portion has an adjustable volume or an adjustable type of fluid and an adjustable gas pressure. Adjustment of the volume or type of fluid and the gas pressure changes a membrane movement to produce selected movement properties according to a mobility scale. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345689 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00057 (20130101) A61B 1/227 (20130101) A61B 8/12 (20130101) A61B 8/58 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240114706 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Biwu Ma (Tallahassee, Florida); Qingquan He (Tallahassee, Florida) |
| ABSTRACT | Methods of passivating a surface. The methods may include providing a mixture including a liquid and a derivative of quinacridone, applying the mixture to a first surface of a film that includes a metal halide perovskite, and annealing the film for a time and a temperature effective to convert the derivative of quinacridone to quinacridone. Composite materials and electronic devices also are provided. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/351601 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/005 (20130101) Organic electric solid-state devices H10K 30/10 (20230201) H10K 30/88 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240114707 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Biwu Ma (Tallahassee, Florida); Qingquan He (Tallahassee, Florida) |
| ABSTRACT | Methods of passivating a surface. The methods may include providing a mixture including a liquid and a derivative of quinacridone, applying the mixture to a first surface of a film that includes a metal halide perovskite, and annealing the film for a time and a temperature effective to convert the derivative of quinacridone to quinacridone. Composite materials and electronic devices also are provided. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/351603 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/005 (20130101) Organic electric solid-state devices H10K 30/10 (20230201) H10K 30/88 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20240108553 | Pineda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Preemie-Pacer, LLC (O'Fallon, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roberta Pineda (Altadena, California); Jeffrey Macler (Tecumseh, Missouri) |
| ABSTRACT | An infant feeding device intended for oral feeding of premature infants. The device is adapted to regulate the flow of fluid fed to the infant. The device may also be adapted to receive and record data relevant to each feeding session. The device further includes disposable components that are appropriate for contact with human milk and formula. |
| FILED | Thursday, September 29, 2022 |
| APPL NO | 17/956199 |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 9/006 (20130101) Original (OR) Class A61J 2200/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109110 | Quigley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut); Joseph G. Michels (Pocono Summit, Pennsylvania); Melinda Sims (Seattle, Washington) |
| ABSTRACT | A control system for controlling extraction of landfill gas from a landfill via a gas extraction system comprising well piping, the landfill gas having a first temperature when extracted, the control system comprising: a gas composition chamber coupled to the well piping and comprising at least one sensor configured to measure one or more characteristics of a landfill gas sample in the gas composition chamber; a temperature control mechanism configured to heat the landfill gas sample in the gas composition chamber to a second temperature at least a threshold amount greater than the first temperature; and a controller configured to control the at least one sensor to measure the one or more characteristics of the landfill gas sample in the gas composition chamber when a temperature of the landfill gas sample in the gas composition chamber is at least the threshold amount greater than the first temperature. |
| FILED | Friday, December 01, 2023 |
| APPL NO | 18/526824 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240109111 | Quigley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut); Jack Rowbottom (Swansea, Massachusetts); Nicole Neff (North Potomac, Maryland) |
| ABSTRACT | A method for use by a system coupled to at least one sensor and at least one flow control mechanism of a gas extraction system, the system comprising at least one controller and configured for use in connection with a landfill gas extraction process for extraction of landfill gas from a landfill via the gas extraction system, the method comprising: using the at least one controller to perform: obtaining, based on at least one measurement made by the at least one sensor, at least one current value indicative of a selected characteristic of the landfill gas extraction process, determining, at discrete time intervals, whether the at least one current value satisfies at least one compliance criterion for the selected characteristic, and when it is determined that the at least one current value does not satisfy the at least one compliance criterion for the selected characteristic, performing a corrective action. |
| FILED | Thursday, December 14, 2023 |
| APPL NO | 18/540281 |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112603 | Moehring et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OtoNexus Medical Technologies, Inc. (Bellevue, Washington) |
| ASSIGNEE(S) | OtoNexus Medical Technologies, Inc. (Bellevue, Washington) |
| INVENTOR(S) | Mark A. Moehring (Seattle, Washington); George Gates (Seattle, Washington); Charlie Corredor (Seattle, Washington); Chad J. McDonald (Seattle, Washington) |
| ABSTRACT | Disclosed herein is a device for modeling properties of an ear. The device includes an artificial tympanic membrane and a housing coupled to the artificial tympanic membrane. The housing defines an interior portion coupled to an interior surface of the artificial tympanic membrane. The interior portion has an adjustable volume or an adjustable type of fluid and an adjustable gas pressure. Adjustment of the volume or type of fluid and the gas pressure changes a membrane movement to produce selected movement properties according to a mobility scale. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345689 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00057 (20130101) A61B 1/227 (20130101) A61B 8/12 (20130101) A61B 8/58 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20240108770 | McCreery et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Zeteo Tech, Inc. (Sykesville, Maryland) |
| ASSIGNEE(S) | Zeteo Tech, Inc. (Sykesville, Maryland) |
| INVENTOR(S) | Thomas McCreery (Sykesville, Maryland); Wayne A. Bryden (Sykesville, Maryland); Emily Caton (Sykesville, Maryland) |
| ABSTRACT | Mobile decontamination systems and microwave assisted decontamination methods for decontaminating a variety of contaminated surfaces disposed external to the system. The systems and methods include treating the surfaces with benign chemical formulations followed by exposing to microwave irradiation for short periods of time to achieve at least 6-log reduction in biological contaminants including viruses and spores of B. anthracis, B. thuringiensis, and P. roqueforti. The formulations include a percarbonate and surfactant in water. |
| FILED | Tuesday, December 05, 2023 |
| APPL NO | 18/529901 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/12 (20130101) A61L 2/22 (20130101) Original (OR) Class A61L 2/24 (20130101) A61L 2/26 (20130101) A61L 2202/14 (20130101) A61L 2202/15 (20130101) A61L 2202/16 (20130101) A61L 2202/25 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112289 | Hastings et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | William Hastings (Billings, Montana); James Matt Gilkeson (Alexandria, Virginia); Mara Winn (Alexandria, Virginia) |
| ABSTRACT | A method to enhance security screening includes generating an augmented reality (AR) interface incorporating scan results from scanning a target in a security scanner. The method displays, to a user of an AR interface, the AR interface mapped to the target and determines guidance including an action relevant to addressing the scan results. The method displays, to the user via the AR interface, the guidance including the action for the user to carry out and monitors user actions. The method displays, to the user via the AR interface, confirmation that the user has carried out the action. |
| FILED | Thursday, December 07, 2023 |
| APPL NO | 18/532768 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/453 (20180201) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113859 | Vemury |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | Systems and methods for secure distribution of biometric matching processing are provided. Certain configurations include homomorphic encrypting of captured biometric information. In some configurations, the biometric information is classified without decryption between a first identity class and a second identity class. The biometric information may be formed as a feature vector. A homomorphic encrypted feature vector may be formed by homomorphic encrypting of the biometric information. |
| FILED | Friday, December 01, 2023 |
| APPL NO | 18/526977 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) Original (OR) Class H04L 9/3231 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20240109067 | McFarland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kirsty A. McFarland (Melrose, Massachusetts); Charles A. Lissandrello (Natick, Massachusetts); Andrew P. Magyar (Acton, Massachusetts); Erin Rosenberger (Quincy, Massachusetts) |
| ABSTRACT | Miniaturized DNA microarrays are described to be used in conjunction with microfluidic channels or microcentrifuge tubes and microcentrifuge filters to reduce sample size, incubation time and to increase overall binding efficiency. |
| FILED | Tuesday, November 28, 2023 |
| APPL NO | 18/520883 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50853 (20130101) Original (OR) Class B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 7/00 (20130101) B01L 2200/16 (20130101) B01L 2200/0689 (20130101) B01L 2300/044 (20130101) B01L 2300/168 (20130101) B01L 2300/0636 (20130101) Centrifuges B04B 3/00 (20130101) B04B 5/0414 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) C12Q 1/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240111970 | Strachan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Paul Strachan (San Carlos, California); Dejan S. Milojicic (Palo Alto, California); Martin Foltin (Fort Collins, Colorado); Sai Rahul Chalamalasetti (Milpitas, California); Amit S. Sharma (Milpitas, California) |
| ABSTRACT | In some examples, a device includes a first processing core comprising a resistive memory array to perform an analog computation, and a digital processing core comprising a digital memory programmable with different values to perform different computations responsive to respective different conditions. The device further includes a controller to selectively apply input data to the first processing core and the digital processing core. |
| FILED | Monday, December 04, 2023 |
| APPL NO | 18/528086 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Hybrid Computing Arrangements G06J 1/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240112029 | Chalamalasetti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sai Rahul Chalamalasetti (Milpitas, California); Paolo Faraboschi (Sant Cugat, Spain); Martin Foltin (Fort Collins, Colorado); Catherine Graves (Milpitas, California); Dejan S. Milojicic (Palo Alto, California); John Paul Strachan (San Carlos, California); Sergey Serebryakov (Saint-Petersburg, Russian Federation) |
| ABSTRACT | A crossbar array includes a number of memory elements. An analog-to-digital converter (ADC) is electronically coupled to the vector output register. A digital-to-analog converter (DAC) is electronically coupled to the vector input register. A processor is electronically coupled to the ADC and to the DAC. The processor may be configured to determine whether division of input vector data by output vector data from the crossbar array is within a threshold value, and if not within the threshold value, determine changed data values as between the output vector data and the input vector data, and write the changed data values to the memory elements of the crossbar array. |
| FILED | Tuesday, December 05, 2023 |
| APPL NO | 18/528935 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class Static Stores G11C 13/0069 (20130101) G11C 2213/77 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20240109956 | SOK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International AIDS Vaccine Initiative (New York, New York); The Scripps Research Institute (La Jolla, California); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Devin SOK (New York, New York); Dennis R. BURTON (La Jolla, California); Vaughn V. SMIDER (La Jolla, California); Ian WILSON (La Jolla, California); Michael CRISCITIELLO (College Station, Texas); Waithaka MWANGI (College Station, Texas) |
| ABSTRACT | The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab′)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody. |
| FILED | Tuesday, September 19, 2023 |
| APPL NO | 18/470044 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/162 (20130101) C07K 16/1063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240110195 | Conant |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Conant (Fort Collins, Colorado) |
| ABSTRACT | Disclosed herein are methods of carbon sequestration using microorganisms, such as soil microorganisms, capable of synthesizing or consuming degradation-resistant L-carbohydrates. In particular, methods of identifying and using microorganisms capable of synthesizing L-carbohydrates are provided, wherein microorganisms that synthesize L-carbohydrates are contacted with a soil source to sequester carbon. Also provided are methods of identifying and incorporating biomolecules such as genes, peptides, and enzymes relevant for L-carbohydrate anabolism or catabolism into plants so the plants synthesize L-carbohydrates or do not consume L-carbohydrates, thereby sequestering carbon. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/486766 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8216 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240109049 | Mehr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mehrad Mehr (Morristown, New Jersey); Bahram Jadidian (Watchung, New Jersey) |
| ABSTRACT | A thermal process system includes a retort assembly that includes a retort chamber, a heating assembly configured to heat the retort chamber, a vessel housing, a process gas inlet, and a sealing gas inlet. The retort assembly is configured to substantially contain one or more process gases in the retort chamber during a thermal process. The vessel housing is positioned around the retort chamber and configured to maintain a pressure or vacuum within the retort chamber. The process gas inlet is configured to receive the one or more process gases into the retort assembly. The sealing gas inlet is configured to receive a sealing gas into the vessel housing. The thermal process system may further include a leak gas detector configured to detect a presence of a leak gas, in which the leak gas includes a gas that is not the one or more process gases in the retort chamber. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/937352 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 6/008 (20130101) B01J 19/0013 (20130101) B01J 19/24 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 3/24 (20130101) C01B 32/05 (20170801) Acyclic or Carbocyclic Compounds C07C 1/12 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113279 | HU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Liangbing HU (Hyattsville, Maryland); Chengwei WANG (College Park, Maryland); Eric D. WACHSMAN (Fulton, Maryland); Venkataraman THANGADURAI (Calgary, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Liangbing HU (Hyattsville, Maryland); Chengwei WANG (College Park, Maryland); Eric D. WACHSMAN (Fulton, Maryland); Venkataraman THANGADURAI (Calgary, Canada) |
| ABSTRACT | A battery cell that include sulfide cathodes are described with examples being suitable for operation at elevated temperatures. Also described are methods of making and using these battery cells. |
| FILED | Thursday, November 30, 2023 |
| APPL NO | 18/524937 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) H01M 4/134 (20130101) H01M 4/136 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20240111591 | Beckmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Bradford Michael Beckmann (Kirkland, Washington); Sooraj Puthoor (Austin, Texas) |
| ABSTRACT | Portions of programs, oftentimes referred to as kernels, are written by programmers to target a particular type of compute unit, such as a central processing unit (CPU) core or a graphics processing unit (GPU) core. When executing a kernel, the kernel is separated into multiple parts referred to as workgroups, and each workgroup is provided to a compute unit for execution. Usage of one type of compute unit is monitored and, in response to the one type of compute unit being idle, one or more workgroups targeting another type of compute unit are executed on the one type of compute unit. For example, usage of CPU cores is monitored, and in response to the CPU cores being idle, one or more workgroups targeting GPU cores are executed on the CPU cores. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/957907 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3009 (20130101) G06F 9/5038 (20130101) Original (OR) Class G06F 9/5072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240113490 | Cheung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stanley Cheung (Milpitas, California); Wayne Victor Sorin (Milpitas, California); Yuan Yuan (Milpitas, California); Raymond G. Beausoleil (Milpitas, California); Di Liang (Santa Barbara, California) |
| ABSTRACT | Examples described herein relate to an optical device. The optical device includes a first microring resonator (MRR) laser having a first resonant frequency and a first free spectral range (FSR). The first FSR is greater than a channel spacing of the optical device. Further, the optical device includes a first frequency-dependent filter formed along a portion of the first MRR laser via a common bus waveguide to attenuate one or more frequencies different from the first resonant frequency. A length of the common bus waveguide is chosen to achieve a second FSR of the common bus waveguide to be substantially equal to the channel spacing to enable a single-mode operation for the optical device. Moreover, the optical device includes a first reflector formed at a first end of the common bus waveguide to enhance a unidirectionality of optical signal within the first MRR laser. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/937071 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/083 (20130101) Original (OR) Class H01S 3/107 (20130101) H01S 3/1062 (20130101) H01S 3/08027 (20130101) H01S 3/08031 (20130101) H01S 3/10053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20240108634 | Gera et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Gera (North Hills, California); Jacquelyn T. Saunders (Los Angeles, California); Brent Holmes (Los Angeles, California); Angelica Benavides-Serrato (Los Angeles, California); Robert N. Nishimura (Los Angeles, California) |
| ABSTRACT | Described herein are compositions and their use in methods and pharmaceutical compositions for inhibiting the binding between Yes-associated protein and TEA domain. Also, described herein are methods of using said compositions capable of inhibiting the binding between Yes-associated protein and TEA domain to treat cancer, inhibit cell proliferation, cell migration, cell invasiveness and tumor growth. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 18/274293 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20240109733 | HRAPSKY |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan J. HRAPSKY (Arlington, Virginia) |
| ABSTRACT | An apparatus that substantially improves the stack quality of delivery items in a delivery item sorting machine by ensuring uniformity of the orientation of the delivery items. The apparatus accommodates toolless installation in the delivery item sorting machine and economical manufacturing options. The apparatus substantially prevents delivery item disorientation and undesired departure of delivery items from the sorting machine. The apparatus reduces operator safety concerns, and increases the net speed of delivery item processing. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/470566 |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 47/883 (20130101) Original (OR) Class B65G 47/8876 (20130101) B65G 2205/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20240108584 | LANNUTTI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John LANNUTTI (Grove City, Ohio); Fan FAN (Xi'an, Shaanxi Province, China PRC); Andrea TEDESCHI (Columbus, Ohio) |
| ABSTRACT | Described are polymeric microparticles, compositions and method of making and using. The polymeric microparticles can include a polymeric core comprising a first polymer and an active agent susceptible to abuse; and a polymeric shell comprising a second polymer. |
| FILED | Monday, January 31, 2022 |
| APPL NO | 18/274964 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) Original (OR) Class A61K 31/197 (20130101) A61K 47/10 (20130101) A61K 47/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, April 04, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240404.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page