FedInvent™ Patent Applications
Application Details for Thursday, May 02, 2024
This page was updated on Tuesday, June 18, 2024 at 02:20 PM GMT
Department of Health and Human Services (HHS)
| US 20240138367 | Weaver et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isaac Weaver (Durham, North Carolina); James Roach (Durham, North Carolina); Timothy Dunn (Durham, North Carolina); Michael Tadross (Durham, North Carolina) |
| ABSTRACT | An observation chamber for three-dimensional kinematic profiling of subject animals. One example system for analyzing free-moving animal subject behavior includes a housing, a transparent arena configured to hold a subject, a camera mounted below the arena, and a mirror system configured to reflect multiple images of the subject in a single field of view of the camera. A height of the housing is less than 80 inches, and a width of the housing is less than 32 inches. The system fits within standard doorway dimensions. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/496375 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 1/031 (20130101) Original (OR) Class A01K 29/005 (20130101) Image or Video Recognition or Understanding G06V 10/12 (20220101) G06V 40/20 (20220101) Pictorial Communication, e.g Television H04N 13/282 (20180501) H04N 23/20 (20230101) H04N 23/56 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240138659 | Gafford et al. |
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| FUNDED BY |
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| APPLICANT(S) | EndoTheia, Inc. (Nashville, Tennessee) |
| ASSIGNEE(S) | EndoTheia, Inc. (Nashville, Tennessee) |
| INVENTOR(S) | Joshua Gafford (Nashville, Tennessee); Jake Childs (Kingston, Tennessee); Laura Davis (San Ramon, California); Caleb Rucker (Knoxville, Tennessee); Patrick Anderson (Nashville, Tennessee); Scott Webster (Nashville, Tennessee); Robert Webster (Nashville, Tennessee) |
| ABSTRACT | The present disclosure provides an endoscopic apparatus and associated methods. The apparatus may include a steerable tool having a first flexible tube concentrically nested within a second flexible tube. The apparatus may include an end cap disposed on the steerable tool, an image sensor disposed on the end cap, and one or more light sources disposed on the end cap. The apparatus may be configured for accessing a region within a middle ear cavity of a patient. As such, the apparatus may further include a flexible tube, through which the steerable tool may extend, as well as a pre-curved rigid tube, through which the flexible tube may extend, thus allowing the apparatus to be deployed for middle ear access. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/238194 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/00029 (20130101) A61B 1/045 (20130101) A61B 1/0052 (20130101) A61B 1/053 (20130101) A61B 1/0055 (20130101) Original (OR) Class A61B 1/0057 (20130101) A61B 1/00101 (20130101) A61B 1/227 (20130101) A61B 1/0655 (20220201) A61B 1/0676 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0138 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240138754 | Apewokin et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Senu Apewokin (Mason, Ohio); William Heineman (Cincinnati, Ohio); Peng Zhang (Cincinnati, Ohio); Sarah Pixley Bell (Cincinnati, Ohio); Michael Smith (Cincinnati, Ohio); Racheal Wilkinson (Wilder, Kentucky) |
| ABSTRACT | A method of assessing gut health in a subject is provided. The method involves placing a device on or near the subject's skin and measuring a level of hydrogen gas emanating through the subject's skin. The device includes an electrochemical sensor capable of detecting hydrogen gas and a means of connecting the device to an apparatus having a central processing unit (CPU). The apparatus provides information on hydrogen gas level and the hydrogen gas level is used to assess gut health of the subject. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498616 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0015 (20130101) A61B 5/742 (20130101) A61B 5/1477 (20130101) A61B 5/4238 (20130101) Original (OR) Class A61B 5/6832 (20130101) A61B 5/6838 (20130101) A61B 5/14546 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240138768 | CHUN et al. |
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| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Young Jae CHUN (Pittsburgh, Pennsylvania); Moataz Mohsen AH ELSISY (Pittsburgh, Pennsylvania); Woon-Hong YEO (Atlanta, Georgia); Robert HERBERT (Atlanta, Georgia) |
| ABSTRACT | An exemplary method and system are disclosed for a fully implantable soft-membrane electronic system that can provide the continuous monitoring of real-time or semi real-time measurements of strain and/or other mechanical properties, via electrical measurements such as capacitance, over an inductive coupling between the measurement system and the implanted device. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/278712 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/076 (20130101) A61B 5/02007 (20130101) A61B 5/4851 (20130101) A61B 5/6862 (20130101) Original (OR) Class A61B 2562/0261 (20130101) A61B 2562/0285 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/915 (20130101) A61F 2002/91566 (20130101) A61F 2210/0076 (20130101) A61F 2240/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240138790 | Specht et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Aaron James Specht (West Lafayette, Indiana); Linda H. Nie (West Lafayette, Indiana) |
| ABSTRACT | The bone measurement system is configured to detect a density of a metallic source within a bone. The bone measurement system includes an x-ray fluorescence (XRF) device, a filter, a radiation detector, a non-transitory computer-readable storage medium storing processor-executable instructions, and a processor. The XRF device may have an x-ray tube including an x-ray source and an anode. The x-ray source may be configured to produce an x-ray beam. The x-ray tube may include a backscatter geometry of around less than one-hundred and eighty degrees to more than ninety degrees. The filter may be disposed along a path of the x-ray beam. The radiation detector may be coupled to the XRF device. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/384073 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4509 (20130101) A61B 6/48 (20130101) Original (OR) Class A61B 6/4208 (20130101) A61B 2560/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240138865 | Gafford et al. |
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| FUNDED BY |
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| APPLICANT(S) | EndoTheia, Inc. (Nashville, Tennessee) |
| ASSIGNEE(S) | EndoTheia, Inc. (Nashville, Tennessee) |
| INVENTOR(S) | Joshua Gafford (Nashville, Tennessee); Scott Webster (Nashville, Tennessee); Patrick Anderson (Nashville, Tennessee); Caleb Rucker (Knoxville, Tennessee); Robert Webster (Nashville, Tennessee) |
| ABSTRACT | The present disclosure provides for an endoscopic apparatus and methods. The apparatus may include a steerable sheath, a control wire disposed within the steerable sheath, and a basket disposed on the control wire. The steerable sheath may be actuated to form a bend, advancing movements of the control wire may cause the basket to project out of the steerable sheath and expand, and retreating movements of the control wire may cause the basket to retract into the steerable sheath and contract. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/238258 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/221 (20130101) Original (OR) Class A61B 2017/00367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240138918 | Feiner et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Steven Feiner (New York, New York); Gabrielle Loeb (Wynnewood, Pennsylvania); Alon Grinshpoon (New York, New York); Shirin Sadri (San Clemente, California); Carmine Elvezio (Bellmore, New York) |
| ABSTRACT | Certain embodiments include a method for assisting a clinician in performing a medical procedure on a patient using augmented reality guidance. The method can include obtaining a three-dimensional model of an anatomic part of the patient. The method can also include aligning the three-dimensional model with data to form augmented reality guidance for the medical procedure. In addition, the method can include presenting the augmented reality guidance to the clinician during the medical procedure using an augmented reality three-dimensional display. |
| FILED | Monday, May 22, 2023 |
| APPL NO | 18/321450 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 2034/107 (20160201) A61B 2034/108 (20160201) Electric Digital Data Processing G06F 3/167 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 19/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139104 | THOMAS et al. |
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| FUNDED BY |
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| APPLICANT(S) | Susan Napier THOMAS (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susan Napier THOMAS (Atlanta, Georgia); Jihoon KIM (Atlanta, Georgia) |
| ABSTRACT | Disclosed herein are thermosensitive hydrogels including at least one thermosensitive polymer and at least one polypeptide. The hydrogels may further include one or more therapeutic and/diagnostic agents and can be used to selectively and controllably deliver such agents to specified tissues and organ systems. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/280397 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Original (OR) Class A61K 9/19 (20130101) A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139112 | Egwuagu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Charles E. Egwuagu (Silver Spring, Maryland); Minkyung Kang (Rockville, Maryland) |
| ABSTRACT | In an embodiment, the invention provides an isolated population of exosomes comprising interleukin-27 (IL-27) or interleukin-35 (IL-35). In an embodiment, the invention also provides a method of preparing a population of exosomes comprising interleukin-27 (IL-27), the method comprising: (a) isolating CD19+B2 cells or B1a cells; (b) activating the isolated cells with a LPS or a BCR agonist to provide activated cells; and (c) isolating exosomes secreted from the activated cells. In an embodiment, the invention also provides a method of preparing a population of exosomes comprising interleukin-35 (IL-35), the method comprising: (a) isolating CD138+plasma cells; (b) activating the isolated cells with a LPS or a BCR agonist to provide activated cells; and (c) isolating exosomes secreted from the activated cells. Additional embodiments of the invention are as described. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 18/271583 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5068 (20130101) Original (OR) Class A61K 38/20 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139120 | Hazen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stanley L. Hazen (Pepper Pike, Ohio); Jonathan Mark Brown (Cleveland, Ohio) |
| ABSTRACT | Provided herein are compositions, systems, and methods for causing weight loss and treating and/or preventing a disease or condition, such as obesity, diabetes, and cancer, with an agent or procedure that inhibits the TMA/FMO3/TMAO pathway in a subject. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/478684 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/14 (20130101) A61K 31/045 (20130101) Original (OR) Class A61K 31/133 (20130101) A61K 31/205 (20130101) A61K 31/616 (20130101) A61K 31/675 (20130101) A61K 31/688 (20130101) A61K 31/4164 (20130101) A61K 31/5375 (20130101) A61K 31/7036 (20130101) A61K 31/7105 (20130101) A61K 35/741 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139148 | Jackson et al. |
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| FUNDED BY |
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| APPLICANT(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mary Jackson (Fort Collins, Colorado); Juan Belardinelli (Fort Collins, Colorado) |
| ABSTRACT | The present disclosure provides compositions and methods related to the treatment of non-tuberculous mycobacterial infections in a subject. In particular, the present disclosure provides compositions comprising an anti-malarial agent and associated methods of treating and/or preventing a non-tuberculous mycobacterial infection in a subject using the composition. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 18/568615 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/357 (20130101) Original (OR) Class A61K 31/5377 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139153 | Schafer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Schafer (Oklahoma City, Oklahoma); Courtney Griffin (Oklahoma City, Oklahoma) |
| ABSTRACT | The present invention includes a method of inducing vascular regression in poorly perfused blood vessels in a subject comprising providing the subject with an effective amount of an inhibitor of an Endothelial ETS Family Transcription Factor. The compounds of the present invention are used in the treatment of retinopathy of prematurity (ROP), diabetic retinopathy (DR), or vascular malformations. |
| FILED | Wednesday, September 15, 2021 |
| APPL NO | 18/044149 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139187 | Ozcan et al. |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Umut Ozcan (Weston, Massachusetts); Ralph Mazitschek (Weston, Massachusetts); Dongxian Guan (Brighton, Massachusetts) |
| ABSTRACT | Formulations of HDAC6 inhibitors passing through the blood brain barrier in hypothalamus and inhibiting HDAC6 in the arctuate AgRP neurons in the hypothalamus, are effective to cause weight loss in obese individuals. These inhibitors also restore leptin sensitivity in leptin-resistant individuals. |
| FILED | Friday, May 26, 2023 |
| APPL NO | 18/324598 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139197 | Zhang |
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| FUNDED BY |
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| APPLICANT(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rugang Zhang (Elkins Park, Pennsylvania) |
| ABSTRACT | Methods of treating cancer, promoting antigen presentation, or increasing CD8+ T cell infiltration in tumors by inhibiting KDMA5 are provided. |
| FILED | Tuesday, October 10, 2023 |
| APPL NO | 18/483886 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 31/7105 (20130101) A61K 38/217 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139210 | DAMSKER et al. |
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| FUNDED BY |
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| APPLICANT(S) | ReveraGen BioPharma, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jesse DAMSKER (Alexandria, Virginia); Eric HOFFMAN (Rockville, Maryland) |
| ABSTRACT | The present disclosure provides methods of treating or reducing the symptoms of muscular dystrophy in a human patient between the age of 1 day and 18 years old, comprising administering to the human patient in need thereof a therapeutically effective amount of a vamorolone and/or a salt thereof. |
| FILED | Monday, August 14, 2023 |
| APPL NO | 18/449312 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139229 | Wu et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Congqing Wu (Lexington, Kentucky); Hong S. Lu (Lexington, Kentucky); Alan Daugherty (Lexington, Kentucky); Zhenyu Li (Lexington, Kentucky); Hua Li (Lexington, Kentucky) |
| ABSTRACT | A method of treating an aortopathy is disclosed, including identifying a subject having or at risk of developing the aortopathy and reducing the expression of and/or activity of gasdermin D (GSDMD) in the subject. The method may include administering to the subject an effective amount of a GSDMD inhibitor. The GSDMD inhibitor may reduce the expression of GSDMD in the subject and/or may reduce the activity of GSDMD in the subject. |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 18/567315 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/145 (20130101) A61K 31/713 (20130101) A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139240 | Ajit |
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| FUNDED BY |
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| APPLICANT(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seena K. Ajit (West Windsor, New Jersey) |
| ABSTRACT | Described herein is a method of treating, ameliorating, and/or preventing post-operative pain in a subject using certain compositions recited in the disclosure. The method comprises administering to the subject a therapeutically effective of a composition comprising a small extracellular vesicle (sEV) or an exosome released by a macrophage. Also described herein is a method of performing surgical operation. The method comprises performing a surgery on the subject, as well as administering to the subject the composition comprising the sEV or exosome herein. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/384625 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/15 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0645 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240139253 — Post-Natal Transplantation Of Factor VIII-Expressing Cells For Treatment of Hemophilia
| US 20240139253 | Almeida-Porada et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina); Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maria Graca N.D. Almeida-Porada (Winston-Salem, North Carolina); Christopher D. Porada (Winston-Salem, North Carolina); Anthony Atala (Winston-Salem, North Carolina); Christopher B. Doering (Atlanta, Georgia); H. Trent Spencer (Marietta, Georgia) |
| ABSTRACT | Disclosed herein are method of treating hemophilia A in a subject comprising injecting the subject with mesenchymal stromal/stem cells (MSC) modified to express high levels of Factor VIII protein. The MSC are isolated prenatally, at birth, or after the subject's birth. The modified MSC may also express high levels von Willebrand factor protein. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/129398 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 38/37 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) C12N 5/0668 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139267 | MILES et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Linde MILES (New York, New York); John POIRIER (New York, New York); Charles RUDIN (New York, New York) |
| ABSTRACT | A method for selecting cancer patient for treatment with Seneca Valley Virus (SVV) by determining expression of ANTXR1 in a cancerous tissue in a cancer patient; and designating the cancer patient as a candidate for treatment with SVV if normal levels or elevated levels of ANTXR1 expression is detected in the cancerous tissue. Also a method for treating a cancer patient with SVV is disclosed. |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/238829 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/768 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/32033 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139279 | Watnick |
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| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Randolph S. Watnick (Newton, Massachusetts) |
| ABSTRACT | Provided herein are cyclic prosaposin peptides and compositions and uses thereof. Exemplary uses include use in the treatment of cancer or in the treatment of inflammatory diseases or disorders. |
| FILED | Thursday, April 13, 2023 |
| APPL NO | 18/134277 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 38/12 (20130101) Original (OR) Class Peptides C07K 7/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139289 | Soliman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| ASSIGNEE(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| INVENTOR(S) | Tarik Soliman (Cambridge, Massachusetts); Daniel B. Hall (Easton, Massachusetts); Rachel Covitz (Allston, Massachusetts); Garry Musso (Harwich, Massachusetts); Caroline Hill (Jamaica Plain, Massachusetts); Ahmet Vakkasoglu (Stoneham, Massachusetts); Poul Strange (Princeton Junction, New Jersey); Tilmann M. Brotz (Berkeley, California) |
| ABSTRACT | The invention provides a long-acting parathyroid hormone peptide (PTH) that is retained in a subject's blood serum for periods of time that greatly exceed the natural hormone. The long-acting PTH is conjugated to at the carbon 3 position of a non-hormonal vitamin D via a scaffold of discreet length that facilitates its purification, detection, solubility, and efficacy at the PTH receptor (PTHR). The PTH may be conjugated to the non-hormonal vitamin D via a 36 mer poly(ethylene glycol) moiety (PTH-PEG36-VitD). The invention also provides optimized manufacturing methods and formulations. The PTH-PEG36-VitD has a vastly-improved serum half-life and bioavailability when compared to a non-conjugated PTH peptide. PTH-PEG36-VitD also significantly increases serum calcium, reduces urinary calcium, and reduces serum phosphate. |
| FILED | Thursday, September 14, 2023 |
| APPL NO | 18/368347 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/29 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/551 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139294 | KHALILI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Temple University - of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kamel KHALILI (Bala Cynwyd, Pennsylvania); Wenhui Hu (Cherry Hill, New Jersey) |
| ABSTRACT | A method of preventing transmission of a retrovirus from a mother to her offspring, by administering to the mother a therapeutically effective amount of a composition comprising a Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated endonuclease, and the two or more different multiplex gRNAs, wherein each of the at least two gRNAs is complementary to a different target nucleic acid sequence in a long terminal repeat (LTR) of proviral DNA of the virus that is unique from the genome of the host cell, cleaving a double strand of the proviral DNA at a first target protospacer sequence with the CRISPR-associated endonuclease, cleaving a double strand of the proviral DNA at a second target protospacer sequence with the CRISPR-associated endonuclease, excising an entire HIV-1 proviral genome, eradicating the HIV-1 proviral DNA from the host cell, and preventing transmission of the proviral DNA to the offspring. |
| FILED | Tuesday, April 11, 2023 |
| APPL NO | 18/298913 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0034 (20130101) A61K 35/12 (20130101) A61K 38/465 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2320/30 (20130101) C12N 2740/16063 (20130101) Enzymes C12Y 301/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139310 | GENDELMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (LincoIn, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Howard E. GENDELMAN (Omaha, Nebraska); Bhavesh Kevadiya (Omaha, Nebraska); Farah Shahjin (Omaha, Nebraska); Milankumar Patel (Omaha, Nebraska) |
| ABSTRACT | The present invention provides porous microparticles, particularly layer-by-layer microparticles, and methods of use thereof. |
| FILED | Wednesday, March 09, 2022 |
| APPL NO | 18/279459 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1647 (20130101) A61K 9/1682 (20130101) A61K 39/215 (20130101) Original (OR) Class A61K 2039/5252 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139315 | ZUO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian ZUO (Omaha, Nebraska); Fei ZHENG (Memphis, Tennessee); Tetsuji YAMASHITA (Memphis, Tennessee); Zoe KELLARD (West Sussex, United Kingdom); Tal TEITZ (Omaha, Nebraska); Jaeki MIN (Memphis, Tennessee); Taosheng CHEN (Germantown, Tennessee) |
| ABSTRACT | Methods and compositions using an inhibitor of EGFR signaling for prevention or an inhibitor of EGFR signaling and a nucleic acid molecule encoding an atonal-associated factor for treatment of hearing loss are described. |
| FILED | Friday, December 15, 2023 |
| APPL NO | 18/541691 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/44 (20130101) A61K 31/58 (20130101) A61K 31/422 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/713 (20130101) A61K 31/4706 (20130101) A61K 31/4709 (20130101) A61K 31/5377 (20130101) A61K 38/1709 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139320 | Majzner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robbie G. Majzner (Palo Alto, California); Aidan Tousley (Stanford, California); Louai Labanieh (Stanford, California); Crystal L. Mackall (Stanford, California); Maria Caterina Rotiroti (Stanford, California) |
| ABSTRACT | The present disclosure generally relates to, inter alia, chimeric antigen receptors (CARs) that contain an intracellular signaling domain without an immune receptor tyrosine based activation motif (ITAM). The disclosure also provides compositions and methods useful for producing such molecules, as well as methods for the detection and treatment of diseases, such as cancer. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 18/547652 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) A61K 39/4631 (20230501) Original (OR) Class A61K 39/4644 (20230501) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70514 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 16/32 (20130101) C07K 2317/31 (20130101) C07K 2317/35 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/12 (20130101) C12N 9/16 (20130101) Enzymes C12Y 207/10002 (20130101) C12Y 301/04011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139324 | Govindan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IMMUNOMEDICS, INC. (Foster City, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Serengulam V. Govindan (Springfield, New Jersey); David M. Goldenberg (Delray Beach, Florida) |
| ABSTRACT | The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an anti-Trop-2 antibody or antigen-binding antibody fragment. In preferred embodiments, the antibody may be an hRS7 antibody. The methods and compostions are of use to treat Trop-2 expressing cancers in human patients, preferably in patients who are resistant to or relapsed from at least one prior anti-cancer therapy, more preferably in patients who are resistant to or relapsed from treatment with irinotecan. The immunoconjugate may be administered at a dosage of 3 mg/kg to 18 mg/kg, preferably 8 to 12 mg/kg, more preferably 8 to 10 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size and reduce or eliminate metastases. Preferred tumors to treat with the subject immunoconjugates include triple-negative breast cancer, HER+, ER+, progesterone+ breast cancer, metastatic non-small-cell lung cancer, a metastatic small-cell lung cancer and metastatic pancreatic cancer. |
| FILED | Friday, September 22, 2023 |
| APPL NO | 18/473133 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/454 (20130101) A61K 31/513 (20130101) A61K 31/675 (20130101) A61K 31/713 (20130101) A61K 31/4184 (20130101) A61K 31/4375 (20130101) A61K 31/4745 (20130101) A61K 31/7088 (20130101) A61K 33/243 (20190101) A61K 45/06 (20130101) Original (OR) Class A61K 47/6803 (20170801) A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 47/6853 (20170801) Peptides C07K 16/30 (20130101) C07K 16/2803 (20130101) C07K 16/2833 (20130101) C07K 16/2887 (20130101) C07K 16/3007 (20130101) C07K 16/3046 (20130101) C07K 2317/24 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) C07K 2317/732 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139329 | Gradinaru et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Viviana Gradinaru (La Canada Flintridge, California); Timothy F. Shay (Pasadena, California); Xinhong Chen (Pasadena, California); Seongmin Jang (Pasadena, California) |
| ABSTRACT | Disclosed herein include novel blood-brain barrier (BBB)-crossing receptors on the BBB interface, targeting peptides and derivatives thereof capable of binding to the novel receptors, and related methods of using the receptors to increase the permeability of the BBB and to deliver an agent to a nervous system (e.g., CNS). In some embodiments, the BBB-crossing receptor is LRP6. Disclosed herein also include recombinant adeno-associated viruses (rAAVs) with increased specificity and transduction efficiency across the BBB and related compositions and methods of treating various diseases and conditions. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/495508 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) Original (OR) Class A61K 48/0041 (20130101) Peptides C07K 14/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139332 | Barbieri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph T. Barbieri (New Berlin, Wisconsin); Eric A. Johnson (Madison, Wisconsin); Sabine Pellett (Madison, Wisconsin); William H. Tepp (Stoughton, Wisconsin); Amanda Przedpelski (Milwaukee, Wisconsin) |
| ABSTRACT | Provided herein are engineered non-catalytic, non-toxic tetanus toxin variants and methods of using such engineered tetanus toxin variants as low dose, protective vaccines that are non-toxic and more potent than their respective chemically inactivated toxoids. In addition, provided herein are conjugate vaccine carriers comprising engineered tetanus toxin variants and methods of using such conjugate vaccines to elicit T-cell dependent immune memory responses which can target a broad spectrum of microbial pathogens as a single vaccine. |
| FILED | Monday, October 03, 2022 |
| APPL NO | 17/959272 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/08 (20130101) A61K 39/0015 (20130101) A61K 47/55 (20170801) A61K 47/6829 (20170801) Original (OR) Class Peptides C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139336 | Lei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yu Lei (Ann Arbor, Michigan); Yee Sun Tan (Ann Arbor, Michigan); Kanokwan Sansanaphongpricha (Ann Arbor, Michigan); Duxin Sun (Ann Arbor, Michigan); Hongwei Chen (Ann Arbor, Michigan); Hongxiang Hu (Ann Arbor, Michigan) |
| ABSTRACT | The present invention provides methods, compositions, systems, and kits comprising nano-satellite complexes and/or serum albumin carrier complexes, which are used for modulating antigen-specific immune response (e.g., enhancing anti-tumor immunity). In certain embodiments, the nano-satellite complexes comprise: a) a core nanoparticle complex comprising a biocompatible coating surrounding a nanoparticle core; b) at least one satellite particle attached to, or absorbed to, the biocompatible coating; and c) an antigenic component conjugated to, or absorbed to, the at least one satellite particle component. In certain embodiments, the complexes further comprise: d) a type I interferon agonist agent. In some embodiments, the serum albumin complexes comprise: a) at least part of a serum albumin protein, b) an antigenic component conjugated to the carrier protein, and c) a type I interferon agonist agent. |
| FILED | Thursday, April 06, 2023 |
| APPL NO | 18/296642 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/02 (20130101) A61K 39/0003 (20130101) A61K 39/0011 (20130101) A61K 39/118 (20130101) A61K 39/385 (20130101) A61K 47/643 (20170801) A61K 47/646 (20170801) A61K 47/6923 (20170801) A61K 47/6929 (20170801) Original (OR) Class A61K 2039/60 (20130101) A61K 2039/572 (20130101) A61K 2039/622 (20130101) A61K 2039/55561 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139376 | JAYASURIYA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chathuraka Teekshana JAYASURIYA (Barrington, Rhode Island); Daniel S. YANG (Irvine, California) |
| ABSTRACT | The invention features compositions and methods for repairing musculoskeletal defects or injuries using a bioactive scaffold comprising fibrinogen, thrombin, SDF-1 and/or KGN as well as methods of making the scaffold. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 18/276593 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/225 (20130101) A61L 27/3817 (20130101) Original (OR) Class A61L 27/3895 (20130101) A61L 2400/06 (20130101) A61L 2430/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139377 | Cullen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); Jason Brant (Wallingford, Pennsylvania); Oladayo Adewole (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided herein is a system, e.g., a living electrode, comprising a biocompatible construct comprising a matrix, and a plurality of auditory neurons. Also disclosed herein are methods of making the system, and methods of using the same for implantation in a subject, for modulating an auditory neuron in the subject, and/or for treating or alleviating a symptom of a hearing loss disorder. Further provided herein are kits comprising the system described herein. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 18/277046 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/52 (20130101) A61L 27/383 (20130101) Original (OR) Class A61L 27/3834 (20130101) A61L 27/3878 (20130101) A61L 27/3886 (20130101) A61L 2430/14 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) A61N 5/0603 (20130101) A61N 5/0622 (20130101) A61N 2005/0605 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139379 | Sharfstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susan Sharfstein (Niskayuna, New York); Yubing Xie (Cohoes, New York); Pujhitha Ramesh (Albany, New York); James Castracane (Marshfield, New York); Melinda Larsen (Albany, New York); Nicholas Moskwa (Bar Harbor, Maine) |
| ABSTRACT | The present disclosure relates to compositions, apparatus and methods for generating one or more scaffolds, including: mixing a hydrogel material and/or an extracellular matrix (ECM) protein in an aqueous solvent to generate an aqueous process solution; and cryoelectrospinning the aqueous process solution onto a plurality of conductive probes extending from a conductive surface of a collector plate disposed within a process chamber under conditions sufficient to generate one or more scaffolds configured to mimic a preselected soft tissue decellularized extracellular matrix. Scaffold compositions are also provided having preselected or tuned characteristics. The scaffolds provide a promising stromal cell delivery vehicle for the remediation of fibrosis. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/108395 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/3834 (20130101) A61L 2300/414 (20130101) A61L 2430/34 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139380 | Mendez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President And Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keegan Mendez (Cambridge, Massachusetts); Ellen Roche (Cambridge, Massachusetts); Connor Verheyen (Boston, Massachusetts); Jennifer Lewis (Cambridge, Massachusetts); Markus Horvath (Somerville, Massachusetts); Sophie Wang (Boston, Massachusetts); Sebastien Uzel (Cambridge, Massachusetts) |
| ABSTRACT | Viscoelastic hydrogel microparticles are used for repair of tissue defects and injuries or filling and occlusion of anatomical structures. These are administered as a microparticle suspension using a catheter, syringe, steerable catheter tip, or comparable technology into the site, where they can be further stabilized by crosslinking or sealing, or through incorporation of a support or encapsulating structure. Materials and methods for solidifying, stabilizing and sealing these materials can be used that are also biocompatible and easily deployed with catheters in the body. The micron sized interstitial spacing provides a scaffold for ingrowth and migration of cells into the gel matrices. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/312492 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 2400/06 (20130101) A61L 2430/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139385 | HANDA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hitesh HANDA (ATHENS, Georgia); Mark GARREN (ATHENS, Georgia); Elizabeth J. BRISBOIS (ATHENS, Georgia); Megan Elizabeth BROOKS (Salt Lake City, Utah); Morgan Musialowski ASHCRAFT (Philadelphia, Pennsylvania) |
| ABSTRACT | Described herein are methods for controlling the release of nitric oxide from a nitric oxide releasing material. The method involves exposing the nitric oxide releasing material to light having a discrete wavelength, wherein the nitric oxide releasing material comprises a (i) a polysiloxane network and (ii) a plurality of nitric oxide-donating moieties covalently bonded to the polysiloxane network. The tunability of nitric oxide release from the nitric oxide releasing materials described herein provides unique therapeutic profiles that correspond to endogenous thresholds of nitric oxide for desired physiological response. The methods described herein can prevent bacterial growth as well as the formation of biofilms and fibrinogen on articles such as, for example, medical devices. |
| FILED | Thursday, October 12, 2023 |
| APPL NO | 18/485737 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) A61K 41/0042 (20130101) A61K 47/59 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/16 (20130101) A61L 29/085 (20130101) Original (OR) Class A61L 31/10 (20130101) A61L 31/16 (20130101) A61L 2300/114 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139514 | LUCAS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy H. LUCAS (Columbus, Ohio); Andrew G. RICHARDSON (Wynnewood, Pennsylvania); Firooz AFLATOUNI (Penn Valley, Pennsylvania); Mark G. ALLEN (Philadelphia, Pennsylvania) |
| ABSTRACT | A sensory system (10, 100) for improving and/or restoring sensation to a foot or hand of a patient. The system (10, 100) includes at least one force sensor (12, 102) implanted subcutaneously within a finger or palm of a hand or on a plantar surface of a foot of a patient and a base unit (18, 104) that is worn externally by the patient or is implanted subcutaneously in the patient. The force sensor (12, 102) is configured to transmit wireless communication signals to the base unit (18, 104) in response to and concerning forces sensed by the force sensor, and base unit (18, 104) is configured to apply peripheral nerve stimulation based on the wireless communication signals received from the force sensor (12) or to transmit the sensory data to a separate neural implant (106). The force sensor (12, 102) transmits the wireless communication signals to the base unit (18, 104) by magnetic human body communication (mHBC). |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 18/278218 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/025 (20130101) A61N 1/0504 (20130101) A61N 1/36003 (20130101) A61N 1/36135 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140909 | Schnermann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| INVENTOR(S) | Martin John Schnermann (Rockville, Maryland); Roger Rauhauser Nani (Frederick, Maryland) |
| ABSTRACT | Heptamethine cyanines for use as fluorescent markers of the biliary system are disclosed. Certain heptamethine cyanines exhibit biliary system specificity and methods for in vivo visualization of a biliary system of a subject are provided. The methods may be for diagnostic purposes and/or for visualization of biliary systems during surgery. |
| FILED | Monday, November 27, 2023 |
| APPL NO | 18/520027 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/006 (20130101) A61K 49/0032 (20130101) A61K 49/0058 (20130101) Heterocyclic Compounds C07D 209/10 (20130101) Original (OR) Class C07D 403/12 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/533 (20130101) G01N 33/582 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140912 | Frederich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida State University Research Foundation, Incorporated. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James H. Frederich (Tallahassee, Florida); Megan M. Solans (Tallahassee, Florida) |
| ABSTRACT | In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein is versatile polyene cyclization strategy that exploits conjugated β-ionyl derivatives. Photomediated disruption of the extended π-system within these chromophores unveils a contra-thermodynamic polyene that engages in a Heck-type cyclization to afford [4.4.1]-propellanes. The connectivity of overbred polycycles generated from this process is controlled by the position of the requisite C-Halide bond. Thus, compared to conventional biomimetic polyene cyclization, this approach allows for complete control of regiochemistry and facilitates incorporation of both electron-rich and electron-deficient (hetero)aryl groups. This strategy was successfully applied to the total synthesis of abietanes such as, for example, taxodione and salviasperanol, two isomeric abietane-type diterpenes that previously could not be prepared along the same synthetic pathway. |
| FILED | Thursday, March 30, 2023 |
| APPL NO | 18/192703 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 13/68 (20130101) C07C 22/08 (20130101) C07C 25/22 (20130101) C07C 35/44 (20130101) C07C 43/215 (20130101) C07C 49/753 (20130101) C07C 49/755 (20130101) C07C 2603/40 (20170501) Heterocyclic Compounds C07D 215/06 (20130101) C07D 215/227 (20130101) Original (OR) Class C07D 307/79 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140952 | LAWRENCE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas LAWRENCE (Lutz, Florida); Harshani LAWRENCE (Lutz, Florida); Ernst SCHÖNBRUNN (Tampa, Florida); Gary REUTHER (Temple Terrace, Florida) |
| ABSTRACT | The present disclosure provides inhibitors of Janus Kinase 2 (JAK2) which may be used in the treatment of medical disorders such as cancer. |
| FILED | Tuesday, January 18, 2022 |
| APPL NO | 18/272497 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/14 (20130101) C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140960 | DONG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yizhou DONG (Columbus, Ohio); Yuebao ZHANG (Columbus, Ohio); Xucheng HOU (Columbus, Ohio) |
| ABSTRACT | The present disclosure relates to compositions and methods for treating cancers, immune disorders, and other preventive and therapeutic applications. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 18/276502 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6901 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 493/04 (20130101) Original (OR) Class Peptides C07K 14/70578 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140993 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Linling He (San Diego, California); Jiang Zhu (San Diego, California); Ian A. Wilson (La Jolla, California) |
| ABSTRACT | The present invention provides redesigned soluble coronavirus S protein derived immunogens that are stabilized via specific modifications in the wildtype soluble S sequences. Also provided in the invention are nanoparticle vaccines that contain the redesigned soluble S immunogens displayed on self-assembling nanoparticles. Polynucleotide sequences encoding the redesigned immunogens and the nanoparticle vaccines are also provided in the invention. The invention further provides methods of using the vaccine compositions in various therapeutic applications, e.g., for preventing or treating coronaviral infections. |
| FILED | Tuesday, November 07, 2023 |
| APPL NO | 18/503260 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) A61K 2039/575 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140997 | REED et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ACCESS TO ADVANCED HEALTH INSTITUTE (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven G. REED (Bellevue, Washington); Rhea N. COLER (Seattle, Washington); Gregory C. IRETON (Seattle, Washington); Sylvie BERTHOLET (Gaithersburg, Maryland) |
| ABSTRACT | The present invention relates to compositions and fusion proteins containing at least two Mycobacterium sp. antigens, and polynucleotides encoding such compositions and fusion proteins. The invention also relates to methods for their use in the treatment, prevention and/or diagnosis of tuberculosis infections. |
| FILED | Monday, January 08, 2024 |
| APPL NO | 18/407367 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 2039/55561 (20130101) Peptides C07K 14/35 (20130101) Original (OR) Class C07K 14/285 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/5695 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141002 | Horowitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Denver (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott Horowitz (Englewood, Colorado); Adam Begeman (Denver, Colorado); Ahhyun Son (Denver, Colorado); Alexa Gomez (Thornton, Colorado); Theodore Litberg (Denver, Colorado) |
| ABSTRACT | Systems and method for providing chaperone activity to a protein-containing compound is disclosed. The method includes selecting a nucleic acid based on one or more of the nucleic acid's particular properties and a specific sequence of the nucleic acid and applying the nucleic acid to a compound comprising one or more proteins to provide chaperone activity to the compound. |
| FILED | Monday, October 09, 2023 |
| APPL NO | 18/483257 |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2310/151 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6839 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141015 | Hirsch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Louis Hirsch (Chapel Hill, North Carolina); Brian Christopher Gilger (Raleigh, North Carolina) |
| ABSTRACT | This invention relates to vectors for delivery of human leukocyte antigen G to the eye and/or to cornea explants and methods of using the same for treatment and/or prevention of corneal transplant rejection and other disorders associated with an immune response and/or vascularization. |
| FILED | Thursday, January 04, 2024 |
| APPL NO | 18/404087 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) A61P 37/06 (20180101) Peptides C07K 14/70539 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14142 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) C12N 2830/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141028 | Kurtis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan Kurtis (Providence, Rhode Island); Dipak K. Raj (Providence, Rhode Island); Alok Das Mohapatra (Providence, Rhode Island); Jenna Zuromski (Providence, Rhode Island) |
| ABSTRACT | Provided herein are methods, compositions and kits for preventing and treating malaria. Also included herein are kits for preventing and treating malaria. |
| FILED | Wednesday, May 10, 2023 |
| APPL NO | 18/315456 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Peptides C07K 16/205 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141056 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew Wang (Durham, North Carolina); Yu Mi (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention provides methods and compositions comprising a particle comprising at least two different targeting agents that each bind a different protein receptor on a T cell surface. |
| FILED | Wednesday, January 10, 2024 |
| APPL NO | 18/409276 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 47/6935 (20170801) A61K 47/6937 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/30 (20130101) C07K 16/2818 (20130101) C07K 16/2878 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141291 | LEE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH and HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Emily LEE (Rockville, Maryland); Caroline STRONG (Chevy Chase, Maryland); Molly BOUTIN (Troy, New York); Marc FERRER (Potomac, Maryland) |
| ABSTRACT | Functional, brain region-specific neural spheroids comprising neuronal cells and optionally glial cells at varying ratios are disclosed, as are methods of making such spheroids and methods for their use, such as for modeling particular brain regions that may be implicated in diseases, or for observing drug effects. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 18/547037 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 5/0622 (20130101) C12N 2502/28 (20130101) C12N 2502/081 (20130101) C12N 2502/086 (20130101) C12N 2506/45 (20130101) C12N 2513/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141324 | Weiss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ron Weiss (Newton, Massachusetts); Breanna E. DiAndreth (Newbury Park, California); Noreen Wauford (Somerville, Massachusetts) |
| ABSTRACT | The present disclosure, at least in part, provides RNA cleavage based engineered bi-stable toggle switch utilizing the Programmable Endonucleolytic Scission-Induced Stability Tuning (PERSIST) platform. Also provided herein, are vectors encoding the engineered bi-stable toggle switch, and uses thereof. |
| FILED | Monday, May 01, 2023 |
| APPL NO | 18/310039 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/1024 (20130101) Original (OR) Class C12N 2310/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141326 | DAR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (, None) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel DAR (Pasadena, California); Dianne K. NEWMAN (Pasadena, California); Kirsten FRIEDA (Pasadena, California); Long CAI (Pasadena, California) |
| ABSTRACT | Method for detecting and barcoding the molecular changes occurring in two or more samples upon exposure to different stimuli. This disclosure herein sets for methods that allow a targeted transcriptome-imaging approach that records both gene-expression and spatial context within microscale assemblies at a single-cell and molecule resolution on biological samples. This disclosure herein sets for methods that allows the application to a variety of biological samples for the study of cellular processes, growth, and interactions between biological samples. |
| FILED | Thursday, February 24, 2022 |
| APPL NO | 18/278586 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1055 (20130101) C12N 15/1058 (20130101) C12N 15/1065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141330 | KITTLER et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Ralf KITTLER (Dallas, Texas); John D. MINNA (Dallas, Texas); Paul M. YENERALL (Dallas, Texas) |
| ABSTRACT | Disclosures herein are directed to methods and compositions for the detection of and screening for mutations that convey phenotypic properties in a protein such as, for example, drug-resistance. Embodiments of the present disclosure include lentiviral-based compositions for enhanced mutagenesis and screening of genes encoding proteins of interest that confer drug resistance according to methods disclosed herein. |
| FILED | Wednesday, January 10, 2024 |
| APPL NO | 18/409612 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1082 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141335 | Schuijers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jurian Schuijers (Somerville, Massachusetts); Abraham S. Weintraub (Cambridge, Massachusetts); John C. Manteiga (Boston, Massachusetts); Richard A. Young (Boston, Massachusetts) |
| ABSTRACT | Disclosed are methods of altering expression of a gene with a promoter region CTCF binding site. Also disclosed are compositions and methods useful for treating a disease or condition involving over-expression or under-expression of a gene with a promoter region CTCF binding site. Further disclosed are cells and non-human animals with modified a promoter region CTCF binding site, as well as methods for screening for compounds that can modify the expression of a gene with a promoter region CTCF binding site. |
| FILED | Monday, June 05, 2023 |
| APPL NO | 18/329541 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141341 | Gersbach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles A. Gersbach (Chapel Hill, North Carolina); Alejandro Barrera (Durham, North Carolina); Tyler S. Klann (Durham, North Carolina); Maria ter Weele (Durham, North Carolina); Gregory E. Crawford (Chapel Hill, North Carolina); Timothy E. Reddy (Durham, North Carolina) |
| ABSTRACT | Disclosed herein am compositions and methods for targeting a novel regulatory element of agene. The compositions may be used in methods of modifying growth of a cell, decreasing cell fitness, increasing cell fitness, and/or treating cancer such as leukemia. |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 18/279996 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2320/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141345 | Trac et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Noah Trac (Covina, California); Eun Ji Paige CHUNG YOO (Rancho Palos Verdes, California) |
| ABSTRACT | A drug delivery for treating renal cancer, and in particular, clear cell renal carcinoma is provides. The drug delivery system includes a plurality of nanoparticles wherein each nanoparticle includes CD70-targeting peptides conjugated thereto and anti-HIF2α siRNAs conjugated thereto. A method for treating renal cancer is also provided. |
| FILED | Monday, October 30, 2023 |
| APPL NO | 18/385174 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 7/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141346 | PLACE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | miRecule, Inc. (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert PLACE (Gaithersburg, Maryland); Anthony SALEH (Gaithersburg, Maryland); Tishan WILLIAMS (Gaithersburg, Maryland) |
| ABSTRACT | Disclosed herein are engineered oligonucleotides for selective inhibition of polypeptide expression and activity. Also disclosed herein are methods of selectively inhibiting polypeptide expression and activity contacting an engineered oligonucleotide with a polynucleotide encoding the polypeptide. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/455756 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 47/549 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/33 (20130101) C12N 2310/141 (20130101) C12N 2310/316 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/351 (20130101) C12N 2310/531 (20130101) C12N 2310/3521 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) C12N 2320/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141348 | COREY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | David COREY (Dallas, Texas); Jiaxin HU (Coppell, Texas) |
| ABSTRACT | Provided herein are compositions and methods for reducing expression of C9orf72 transcripts in cells containing expanded intronic GGGGCC regions, including those in subjects having or at risk of developing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). |
| FILED | Thursday, October 19, 2023 |
| APPL NO | 18/490131 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/3231 (20130101) C12N 2310/3521 (20130101) C12N 2320/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141349 | Stamm et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stefan Stamm (Lexington, Kentucky); Justin Ralph Welden (Lexington, Kentucky) |
| ABSTRACT | The present disclosure concerns isolated double stranded (ds) silencing RNA (siRNA) to target a backsplice junction between exons 12 and 7 in the MAPT gene. The ds siRNA include at least one nucleotide from the 3′ terminus of exon 12 linked to at least one nucleotide of the 5′ terminus of exon 7, thereby overlapping the backsplice junction. Targeting the junction ensure that that ds siRNA are limited in targeting the circular RNA produced by the backsplicing while allowing normal expression of the MAPT gene. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498834 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141362 | Khvorova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Loïc Maurice René Jean Roux (Worcester, Massachusetts); Ken Yamada (Westborough, Massachusetts) |
| ABSTRACT | This disclosure relates to novel modified oligonucleotides. Novel modified siRNA are also provided. |
| FILED | Friday, September 01, 2023 |
| APPL NO | 18/459992 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141379 | Asokan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aravind Asokan (Chapel Hill, North Carolina); Erin Borchardt (Naperville, Illinois); Rita Meganck (Raleigh, North Carolina); William F. Marzluff (Hillsborough, North Carolina) |
| ABSTRACT | This invention is directed to AAV compositions for circular RNA expression and methods of expressing covalently closed, circular RNA. |
| FILED | Wednesday, June 14, 2023 |
| APPL NO | 18/334530 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2840/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141399 | Cooper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Matthew Cooper (San Diego, California); Jeff Hasty (Encinitas, California) |
| ABSTRACT | Provided herein are methods for generating multiplex CRISPR arrays based on annealing and ligating single-stranded DNA oligonucleotides using bridge oligonucleotides. The methods described herein include providing a first oligonucleotide comprising a CRISPR repeat sequence or a portion thereof, and a first portion of a first spacer sequence at its 3′ end; providing a second oligonucleotide comprising, from 5′ to 3′, a second portion of the first spacer sequence, the CRISPR repeat sequence, and a first portion of a second spacer sequence; providing a bridge oligonucleotide comprising a sequence substantially complementary to the first spacer sequence; allowing the first oligonucleotide and the second oligonucleotide to hybridize with the bridge oligonucleotide; and ligating the first and second oligonucleotide. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 18/278695 |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141408 | Shen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women’s Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jie Shen (Brookline, Massachusetts) |
| ABSTRACT | Described herein are cell-based high-throughput screening (HTS) assays for the identification of activators of γ-secretase. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 18/568612 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2503/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) Original (OR) Class C12Q 1/6851 (20130101) C12Q 1/6897 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141411 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Albert Cheng (Bar Harbor, Maine); Zukai Liu (Bar Harbor, Maine) |
| ABSTRACT | Provided herein, in some aspects, is a multiplex RNA targeting system that enables live cell imaging and/or modification of multiple RNA targets. Specifically, the disclosure provides a method of live cell imaging of ribonucleic acid (RNA), or targeting RNA in a live cell, comprising: (a) delivering to a cell an RNA-editing complex that comprises a catalytically inactive Cas13 (dCas13) nuclease, a Cas 13 guide RNA (gRNA) comprising an RNA aptamer sequence, and a detectable molecule linked to an RNA-binding domain (RBD), or an RNA effector molecule linked to an RBD sequence that specifically binds to the RNA aptamer sequence; and (b) imaging the detectable molecule or RNA aptamer and RBD binding. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 18/280198 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Original (OR) Class Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141412 | Savage et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Savage (Berkeley, California); Patrick Hsu (Berkeley, California); Noam Prywes (Berkeley, California); Emeric J. Charles (Berkeley, California); Gavin J. Knott (Berkeley, California); John James Desmarais (Berkeley, California); Shineui Kim (Berkeley, California); Eli Dugan (Berkeley, California); Maria Lukarska (Berkeley, California); Sita S. Chandrasekaran (Berkeley, California); Nicholas C. Lammers (Berkeley, California); Tina Y. Liu (Berkeley, California); Amanda Mok (Berkeley, California); Liana Lareau (Berkeley, California); Brittney Wai-Ling Thornton (Berkeley, California) |
| ABSTRACT | Described herein are nucleic acid detection compositions and systems comprising an internal nuclease chain reaction (NCR) for signal amplification and methods of using these NCR-containing compositions and systems. |
| FILED | Tuesday, May 18, 2021 |
| APPL NO | 17/926441 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) Original (OR) Class C12Q 1/6876 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141430 | Sullenger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bruce Sullenger (Durham, North Carolina); Bethany Gray (Durham, North Carolina); Michael Nichols (Durham, North Carolina) |
| ABSTRACT | Provided herein are compositions and methods for sorting and/or identifying live cells. The compositions and methods provide for staining of live cells with aptamer so particular cells can be identified within or sorted from a heterogeneous population of live cells and subsequent reversal of the staining to prepare sorted and/or identified cells in their native state. |
| FILED | Thursday, March 30, 2023 |
| APPL NO | 18/128949 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2310/3517 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141440 | Counter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Counter (Durham, North Carolina); Siqi Li (Durham, North Carolina) |
| ABSTRACT | The present invention provides methods and kits for the detection of rare genetic mutations in the human KRAS gene. The methods provided herein use specific restriction enzymes that target regions in the 3′ end of a region of interest within the human KRAS gene paired with primers designed for the specific amplification of the digested regions of interest to identify samples comprising these rare mutations. |
| FILED | Wednesday, November 01, 2023 |
| APPL NO | 18/499880 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142436 | PFEIL |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jacob PFEIL (Santa Cruz, California) |
| ABSTRACT | Candidate cancer antigens are identified using transposable elements. Differential expression levels are determined for proteins using baseline expression levels (using measurements of healthy tissue) and tumor expression levels (using measurements of tumor tissue). Protein(s) having a differential expression level greater than a threshold are selected. Cancer vaccine(s) are generated for the selected cancer antigens (s). Particular cancer vaccine(s) are selected for a patient based on differential expression levels for proteins using baseline expression levels of the patient and tumor expression levels of the patient. A vaccine for protein(s) having a differential expression level greater than a threshold can be selected. A microarray can be used for the measurements of the patient. A first array of probes can hybridize to RNA from transposable elements. A second array of probes can hybridize to RNA of different MHC haplotypes. A third array of probes can hybridize to RNA of different APOBEC genotypes. |
| FILED | Monday, October 19, 2020 |
| APPL NO | 17/769277 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) Original (OR) Class G01N 33/6848 (20130101) G01N 2333/70539 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142437 | Fischer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Eric S. Fischer (Chestnut Hill, Massachusetts); Katherine Donovan (Boston, Massachusetts) |
| ABSTRACT | Presented are methods of assessing the teratogenicity of agents by measuring the degradation of SALL4, and related compounds with reduced teratogenicity. Provided herein is a method for assessing the teratogenicity of an agent comprising: contacting an agent with SALL4; and measuring levels of SALL4, wherein the agent is teratogenic if SALL4 levels are substantially reduced in the presence of the agent relative to in the absence of the agent. |
| FILED | Friday, September 22, 2023 |
| APPL NO | 18/371858 |
| CURRENT CPC | Enzymes C12Y 603/02019 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/5014 (20130101) Original (OR) Class G01N 2500/10 (20130101) G01N 2500/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142444 | LIOTTA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GEORGE MASON UNIVERSITY (Fairfax, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lance LIOTTA (Fairfax, Virginia); Marissa A. HOWARD (Fairfax, Virginia); Alessandra Luchini KUNKEL (Fairfax, Virginia); Sameen YUSUF (Fairfax, Virginia); Sara SHARIF (Fairfax, Virginia); Ruben MAGNI (Fairfax, Virginia) |
| ABSTRACT | The invention relates to a relates to a highly sensitive, non-invasive diagnostic method for detection infectious diseases. In one embodiment, the invention relates to novel rapid, self-working, visual field test for a panel of disease specific derived biomarkers. In one embodiment, the invention comprises a collecting device comprising a collapsible non hygroscopic net tethered with immobilized nanoparticles to capture and concentrate a target analyte present in a fluid; wherein the nanoparticle comprises a core and a shell, wherein the core comprises a molecular bait. The invention also relates to identification of biomarkers for identification of various pathogenic diseases. |
| FILED | Thursday, June 25, 2020 |
| APPL NO | 17/622403 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5695 (20130101) G01N 33/54346 (20130101) Original (OR) Class G01N 33/56905 (20130101) G01N 33/56911 (20130101) G01N 2333/20 (20130101) G01N 2333/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142445 | Bailey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Genalyte, Inc. (San Diego, California); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan C. Bailey (Urbana, Illinois); Abraham J. Qavi (Champaign, Illinois); Jared T. Kindt (Champaign, Illinois); Ji-Yeon Byeon (Daejeon, South Korea); Matthew S. Luchansky (Champaign, Illinois); Melinda S. McClellan (Champaign, Illinois); Adam L. Washburn (Savoy, Illinois); Tate Owen (Del Mar, California); Martin Anthony Gleeson (San Diego, California); Lawrence C. Gunn (Encinitas, California) |
| ABSTRACT | Various embodiments are drawn to systems and methods for detecting an analyte of interest in a sample including an optical sensor, a capture probe attached to a surface of the optical sensor wherein the capture probe is capable of binding to the analyte to form a duplex or complex, and an antibody capable of binding to the analyte, duplex, or complex. In several embodiments, systems and methods further include a particle attached to the antibody or capable of binding to the antibody. In several embodiments, systems and methods for analyte detection feature one or more of the following: high detection sensitivity and specificity, scalability and multiplex capacity, ability to analyze large analytes, and ability to detect or measure multiple individual binding events in real-time. |
| FILED | Wednesday, September 06, 2023 |
| APPL NO | 17/903550 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6825 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/75 (20130101) G01N 21/7746 (20130101) G01N 33/54373 (20130101) Original (OR) Class G01N 2021/7789 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142454 | Kraner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susan D. Kraner (Lexington, Kentucky); Rodney P. Guttmann (Contonment, Florida); Christopher M. Norris (Lexington, Kentucky); Jenna Leigh Gollihue (Lexington, Kentucky) |
| ABSTRACT | Provided herein are antibodies, or antigen-binding portions thereof, which specifically bind to pathologic forms of calcineurin. The invention further provides a method of obtaining such antibodies and nucleic acids encoding the same. The invention further relates to compositions and methods for use of these antibodies, including methods for staining pathological tissue. |
| FILED | Monday, November 27, 2023 |
| APPL NO | 18/520159 |
| CURRENT CPC | Peptides C07K 16/40 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 33/5091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142473 | O'BRYANT |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of North Texas Health Science Center at Fort Worth (Fort Worth, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sid E. O'BRYANT (Aledo, Texas) |
| ABSTRACT | The present disclosure relates to a method of treating a subject having a proinflammatory endophenotype profile with celecoxib or naproxen to improve cognition or to prevent cognitive decline or dysfunction in the subject. In another aspect, the present disclosure relates to a method of screening a subject for inclusion an NSAID or a PPAR-7 agonist clinical trial. In another aspect, the present disclosure relates to a method of determining a surrogate outcome of an NSAID or a PPAR-7 agonist clinical trial. In yet another aspect, the present disclosure relates to a method of treating an Alzheimer's disease patient having both a proinflammatory endophenotype profile and a metabolic endophenotype profile with a PPAR-7 agonist to improve cognition or to prevent cognitive decline or dysfunction in the patient. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/548840 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2800/52 (20130101) G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142474 | Montell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Craig Montell (Santa Barbara, California); Yinpeng Zhan (Santa Barbara, California); Avinash Chandel (Santa Barbara, California) |
| ABSTRACT | Opsin proteins are GPCRs known for light perception. Here it is shown that these receptors are also expressed in chemosensory cells and function as chemosensory receptors activated by a range of molecules, including tastants such as theobromine, for which a receptor has not previously been known. Provided are novel assay systems for assessing chemosensory opsin activation by chemical ligands. By these assays, novel ligands of chemosensory opsins may be identified, the chemosensory properties of molecules may be evaluated; and the modulation of chemosensory properties by modifications or modulators may be tested. |
| FILED | Thursday, February 24, 2022 |
| APPL NO | 18/547840 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 2217/054 (20130101) A01K 2227/105 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class G01N 2333/726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142475 | Philips et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer Philips (St. Louis, Missouri); Pallavi Chandra (St. Louis, Missouri); Heloise Coullon (St. Louis, Missouri) |
| ABSTRACT | Methods for diagnosis of bacterial infections (e.g., tuberculosis) are disclosed. In particular, the disclosure relates to the use of a panel of biomarkers for aiding diagnosis, prognosis, and treatment of bacterial infections such as tuberculosis. The identified biomarkers can be used to detect active infection as well as bacterial burden, and for monitoring responses to treatment. |
| FILED | Thursday, February 24, 2022 |
| APPL NO | 18/278740 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 2405/02 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142757 | HORMIGO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New york, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | RICHARD HORMIGO (New York, New York); RUDY BEHNIA (New york, New York); SEYED NAVID MOUSAVI (New york, New York); DARCY PETERKA (New york, New York); TANYA TABACHNIK (New york, New York) |
| ABSTRACT | Exemplary systems, method and compute-accessible medium can be provided, e.g., for a visual stimulation or an optogenetic activation during a scan of at an object. For example, it is possible to utilize a controller which can be configured to receive signal information regarding the scan, and to precisely control a light engine. The exemplary control of the light engine can be used to activate and deactivate a light source or a plurality of light sources (e.g., one or more at least one light emitting diodes). using the signal information. For example, a digital micromirror device can be utilized through which the light engine is precisely controlled for a full field projection, or patterned projection, wherein the light engine can comprise up to eight high power light sources. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/384201 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0048 (20130101) Original (OR) Class G02B 21/0076 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 45/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142760 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the university of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bo Huang (San Francisco, California); Bin Yang (San Francisco, California) |
| ABSTRACT | In one embodiment, a microscopy system includes a first objective positioned adjacent to a sample to be imaged, the first objective being configured to both illuminate the sample with light and collect light from the sample, and a remote imaging module positioned remotely from the first objective and the sample, the remote imaging module being configured to rotate the image plane of the collected light. |
| FILED | Thursday, December 21, 2023 |
| APPL NO | 18/392789 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/06 (20130101) G02B 21/16 (20130101) G02B 21/18 (20130101) G02B 21/33 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240144418 | Cai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dawen Cai (Ann Arbor, Michigan); Logan A. Walker (Ann Arbor, Michigan) |
| ABSTRACT | Methods and systems for storing and accessing image data in a scalable format are disclosed herein. An example method includes (i) generating an image data array representative of one or more images captured by one or more cameras associated with an apparatus; (ii) generating a set of first division arrays, each first division array representative of a different subset of the image data array and sharing a first resolution size; (iii) generating a set of second division arrays, each second division array representative of a different subset of one of the first division arrays in the set of first division arrays and sharing a second resolution size smaller than the first resolution size; and (iv) storing, in a memory, the set of second division arrays such that the set of second division arrays is stored according to an order of the set of first division arrays. |
| FILED | Tuesday, October 10, 2023 |
| APPL NO | 18/378485 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/40 (20130101) Original (OR) Class G06T 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240144704 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Avenue Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | c/o The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiao Wang (Cambridge, Massachusetts); Jia Liu (Cambridge, Massachusetts); Yichun He (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides methods for identifying cells in an image. An apparatus for identifying cells in an image is also provided by the present disclosure. Further provided herein is a non-transitory computer-readable storage medium for performing the methods disclosed herein. Methods of diagnosing a disease or disorder and of treating a disease or disorder in a subject using the methods disclosed are also provided herein. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 18/277950 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/44 (20220101) G06V 20/69 (20220101) Original (OR) Class G06V 2201/03 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145039 | Remes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thermo Finnigan LLC (San Jose, California); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip M. Remes (Livermore, California); Lilian Heil (Seattle, Washington); Michael J. MacCoss (Seattle, Washington); Ping F. Yip (Salem, Massachusetts) |
| ABSTRACT | A system for performing dynamic DIA directs a mass spectrometer to acquire, based on an acquisition schedule that schedules a plurality of acquisition cycles, MS2 spectra of product ions derived from analytes included in a sample as the analytes elute from a separation system. The acquisition schedule specifies, for each acquisition cycle included in the plurality of acquisition cycles, a dynamic precursor m/z range based on an expected elution time of the analytes. The product ions are produced from precursor ions isolated using an isolation window successively positioned throughout the dynamic precursor m/z range during each acquisition cycle. The system detects an elution time shift in the elution time of the analytes as the analytes elute and adjusts the acquisition schedule based on the detected elution time shift. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 17/976260 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/10 (20190201) G16B 40/10 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240139104 | THOMAS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Susan Napier THOMAS (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susan Napier THOMAS (Atlanta, Georgia); Jihoon KIM (Atlanta, Georgia) |
| ABSTRACT | Disclosed herein are thermosensitive hydrogels including at least one thermosensitive polymer and at least one polypeptide. The hydrogels may further include one or more therapeutic and/diagnostic agents and can be used to selectively and controllably deliver such agents to specified tissues and organ systems. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/280397 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Original (OR) Class A61K 9/19 (20130101) A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139118 | Ashraf et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ali Ashraf (McAllen, Texas); Stephen Dalton McLaughlin (Princeton, New Jersey); Mehdi Javanmard (Princeton Junction, New Jersey); Francois Berthiaume (Metuchen, New Jersey); Aaron D. Mazzeo (Edison, New Jersey) |
| ABSTRACT | Devices and methods for selectively accessing tissue for sensing or drug release are provided. A device includes an array of wells formed in a substrate supporting a plurality of membranes. Each membrane is disposed at a well opening of one of the wells of the array. The device further includes an actuator and electronics configured to control the actuator to supply a vibration through the substrate. The supplied vibration is configured to selectively rupture one of the plurality of membranes at a defined timepoint to selectively give access to tissue through a well opening. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/496604 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/703 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139197 | Zhang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rugang Zhang (Elkins Park, Pennsylvania) |
| ABSTRACT | Methods of treating cancer, promoting antigen presentation, or increasing CD8+ T cell infiltration in tumors by inhibiting KDMA5 are provided. |
| FILED | Tuesday, October 10, 2023 |
| APPL NO | 18/483886 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Original (OR) Class A61K 31/7105 (20130101) A61K 38/217 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139315 | ZUO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (Memphis, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian ZUO (Omaha, Nebraska); Fei ZHENG (Memphis, Tennessee); Tetsuji YAMASHITA (Memphis, Tennessee); Zoe KELLARD (West Sussex, United Kingdom); Tal TEITZ (Omaha, Nebraska); Jaeki MIN (Memphis, Tennessee); Taosheng CHEN (Germantown, Tennessee) |
| ABSTRACT | Methods and compositions using an inhibitor of EGFR signaling for prevention or an inhibitor of EGFR signaling and a nucleic acid molecule encoding an atonal-associated factor for treatment of hearing loss are described. |
| FILED | Friday, December 15, 2023 |
| APPL NO | 18/541691 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/44 (20130101) A61K 31/58 (20130101) A61K 31/422 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/713 (20130101) A61K 31/4706 (20130101) A61K 31/4709 (20130101) A61K 31/5377 (20130101) A61K 38/1709 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139376 | JAYASURIYA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chathuraka Teekshana JAYASURIYA (Barrington, Rhode Island); Daniel S. YANG (Irvine, California) |
| ABSTRACT | The invention features compositions and methods for repairing musculoskeletal defects or injuries using a bioactive scaffold comprising fibrinogen, thrombin, SDF-1 and/or KGN as well as methods of making the scaffold. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 18/276593 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/225 (20130101) A61L 27/3817 (20130101) Original (OR) Class A61L 27/3895 (20130101) A61L 2400/06 (20130101) A61L 2430/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139485 | CHEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kuen-Ren CHEN (Pullman, Washington); Maher HN AMER (Pittsburgh, Pennsylvania) |
| ABSTRACT | Microneedle arrays provided herein enable a minimally invasive platform for ocular drug delivery. Such a design and manufacture technique includes a conformable preformed interlocking mechanism configured about an elongated structure wherein the conformable preformed interlocking mechanism is arranged with a width that decreases in the needle tip direction and decreases in the base direction; and wherein each of the microneedles to include the conformable preformed interlocking mechanism is arranged to increase in area upon fluid tissue contact and decrease in area upon illumination with light. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 18/547903 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0046 (20130101) A61M 2037/0053 (20130101) A61M 2037/0061 (20130101) A61M 2210/0612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139728 | TSALOGLOU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mammoth Biosciences, Inc. (Brisbane, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maria-Nefeli TSALOGLOU (San Francisco, California); Janice Sha CHEN (San Francisco, California); James Paul BROUGHTON (South San Francisco, California); Daniel Thomas DRZAL (Pacifica, California); Sarah Jane SHAPIRO (Pacifica, California); Clare Louise FASCHING (Redwood City, California); Carley Gelenter HENDRIKS (Burlingame, California); Jesus CHING (Saratoga, California); Sonal JAIN (San Mateo, California) |
| ABSTRACT | The application provides devices, kits and methods for a streamlined lateral flow assay for sample preparation, optional amplification, and detection of a target nucleic acid using programmable nuclease reagents. |
| FILED | Tuesday, November 15, 2022 |
| APPL NO | 18/055814 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) Original (OR) Class B01L 2300/069 (20130101) B01L 2400/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139865 | Zuhlke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures, Inc. (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig Zuhlke (Lincoln, Nebraska); Andrew Reicks (Lincoln, Nebraska); Christos Argyropoulos (Lincoln, Nebraska); Andrew Butler (Lincoln, California); George Gogos (Lincoln, Nebraska); Dennis R. Alexander (Lincoln, Nebraska) |
| ABSTRACT | A method for laser-processing a metallic surface to produce a functionalized metallic surface comprises: providing a material substrate having the surface; and applying a pulsed laser beam to a region of the surface, the pulsed laser beam being applied at a non-normal angle to the surface, wherein material in the region of the surface ablates due to the applied pulsed laser beam and wherein at least a portion of the ablated material redeposits on the surface to produce one or more material-coated structures angled at the non-normal angle with respect to the surface, wherein the surface having the one or more material-coated structures is the functionalized surface. The functionalized metallic surface has broadband directional emissivity independent of polarization. |
| FILED | Thursday, August 03, 2023 |
| APPL NO | 18/364942 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/123 (20130101) B23K 26/352 (20151001) B23K 26/0624 (20151001) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 24/082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140592 | Yerant et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Stephen Yerant (Milford, Connecticut); Timothy Heising Bean (Trumbull, Connecticut); Stephen V. Poulin (Milford, Connecticut) |
| ABSTRACT | A control input operable by a user for controlling movement of an aircraft includes a base portion configured for coupling to a support surface, the base portion biased towards a neutral position defined along a central axis and pivotable to a plurality of angular positions relative to the central axis. The control input also includes a grip portion having inputs for controlling movement of the aircraft and pivotally coupled to the base portion, the grip portion pivotable between a first position in which the grip portion extends from the base portion and a second position in which the grip portion is pivoted relative to the base portion. Further, the control input includes a lock mechanism for locking the grip portion in the first position wherein releasing the lock mechanism allows the grip portion to move to the second position. |
| FILED | Thursday, October 27, 2022 |
| APPL NO | 17/974824 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 13/14 (20130101) Original (OR) Class B64C 13/0421 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140611 | Boyer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason Boyer (Swedesboro, New Jersey) |
| ABSTRACT | Exhaust systems having adjustable nozzles and related methods are disclosed. An example exhaust system includes a nozzle. A portion of the nozzle is moveable from a first position to a second position to change an angle of convergence of the nozzle. The example exhaust system includes an exit area. The portion of the nozzle is at least partially disposed in the exit area. An opening is defined between the exit area and the portion of the nozzle disposed in the exit area. A size of the opening is to change in response to movement of the portion of the nozzle. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 17/978011 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/04 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/04 (20130101) Original (OR) Class B64D 2033/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140882 | Sotiriou-Leventis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Chariklia Sotiriou-Leventis (Rolla, Missouri); Nicholas Leventis (Worcester, Massachusetts); Rushi Soni (Rolla, Missouri); Vaibhav Edlabadkar (Rolla, Missouri); Parwani Rewatkar (Hillsboro, Oregon); ABM Shaheen ud Doulah (Rolla, Missouri) |
| ABSTRACT | Novel methods of synthesizing amorphous carbon and graphitic carbon aerogels are provided. The carbon aerogels produced by these methods are highly porous, monolithic carbon aerogels and are extremely robust. Specifically, the amorphous carbon aerogels have high surface areas and large micropore volumes. Due to these extraordinary properties, these aerogels possess high carbon dioxide (CO2) sorption capacities and are highly selective towards CO2 versus other gases, such as H2 and N2. As a result, the amorphous carbon aerogels can be used to effectively capture or remove CO2 from the air and/or from flue gases. Furthermore, the graphitic carbon aerogels notably have high graphite content, crystallite size, and graphite quality, of which are comparable to those of commercial graphite. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 18/554074 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 38/0022 (20130101) Original (OR) Class C04B 2235/48 (20130101) C04B 2235/5409 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/583 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141003 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fuzhong Zhang (St. Louis, Missouri); Jingyao Li (St. Louis, Missouri) |
| ABSTRACT | The present disclosure is directed to systems and methods for synthesizing a recombinant polymeric amyloid and recombinant polymeric amyloid fibers. In some embodiments, the methods comprise synthesizing tandem repeats of an amyloid peptide and a glycine-rich linker peptide in vivo in a heterologous host. In other embodiments, the recombinant polymeric amyloid fibers comprise a plurality of polymeric amyloid fibrils each comprising a plurality of β-sheet crystals, wherein the β-sheet crystals comprise tandem repeats of an amyloid peptide and a glycine-rich linker peptide, and wherein the plurality of β-sheet crystals are aligned in parallel with a fiber axis. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 18/278707 |
| CURRENT CPC | Peptides C07K 14/4711 (20130101) Original (OR) Class C07K 14/43518 (20130101) C07K 2319/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141226 | Liotta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGE MASON UNIVERSITY (Fairfax, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lance Allen Liotta (Fairfax, Virginia); Yali Kong (Fairfax, Virginia); Alessandra Kunkel Luchini (Fairfax, Virginia); Amanda Haymond Still (Fairfax, Virginia); Marissa Howard (Fairfax, Virginia); Ali Andalibi (Fairfax, Virginia) |
| ABSTRACT | In an embodiment, a method comprising: adding a composition comprising a photochromic dye to a sample having an opioid compound to form a reacted product; illuminating an electromagnetic ray having a wavelength between about 100 nm to about 600 nm on the photochromic dye; and detecting the opioid compound in the sample. |
| FILED | Monday, August 07, 2023 |
| APPL NO | 18/366217 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/02 (20130101) Original (OR) Class C09K 2211/1088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141326 | DAR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (, None) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel DAR (Pasadena, California); Dianne K. NEWMAN (Pasadena, California); Kirsten FRIEDA (Pasadena, California); Long CAI (Pasadena, California) |
| ABSTRACT | Method for detecting and barcoding the molecular changes occurring in two or more samples upon exposure to different stimuli. This disclosure herein sets for methods that allow a targeted transcriptome-imaging approach that records both gene-expression and spatial context within microscale assemblies at a single-cell and molecule resolution on biological samples. This disclosure herein sets for methods that allows the application to a variety of biological samples for the study of cellular processes, growth, and interactions between biological samples. |
| FILED | Thursday, February 24, 2022 |
| APPL NO | 18/278586 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1055 (20130101) C12N 15/1058 (20130101) C12N 15/1065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141519 | Toma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Francesca Maria Toma (Ann Arbor, Michigan); Guosong Zeng (Ann Arbor, Michigan); Tadashi Ogitsu (Ann Arbor, Michigan); Tuan Anh Pham (Ann Arbor, Michigan); The Regents of the University of Michigan (Ann Rbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Francesca Maria Toma (Berkeley, California); Tadashi Ogitsu (Dublin, California); Zetian MI (Ann Arbor, Michigan); Srinivas Vanka (Ann Arbor, Michigan); Guosong Zeng (Berkeley, California); Tuan Anh Pham (Livermore, California); Yixin Xiao (Ann Arbor, Michigan) |
| ABSTRACT | A method of fabricating a device includes providing a substrate of the device, forming a structure of the device, the structure being supported by the substrate, having a semiconductor composition, and including a surface, where nitrogen is present at the surface, and incorporating oxygen into the surface to form a stabilizing layer on the surface. Incorporating oxygen into the surface is implemented such that the stabilizing layer includes a uniform distribution of an oxynitride material |
| FILED | Monday, February 28, 2022 |
| APPL NO | 18/279181 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 11/052 (20210101) C25B 11/059 (20210101) C25B 11/087 (20210101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02175 (20130101) H01L 21/02241 (20130101) H01L 29/045 (20130101) H01L 29/401 (20130101) H01L 29/513 (20130101) H01L 29/518 (20130101) H01L 29/2003 (20130101) H01L 33/16 (20130101) H01L 33/32 (20130101) H01L 33/44 (20130101) H01L 2933/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141878 | SAHIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVRTSITY IN THE CITY OF NEW YORK (New YORK, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVRTSITY IN THE CITY OF NEW YORK (New Tork, New York) |
| INVENTOR(S) | Ozgur SAHIN (New York, New York); Eran SCHENKER (New York, New York); Yocheved UNGAR (New York, New York); Onur Cakmak (Minelola, New York) |
| ABSTRACT | Systems and methods for developing a composite material are disclosed. The system can include a plurality of particles and a plurality of polymers. The plurality of particles can generate mechanical force in response to changing relative humidity, and the plurality of filaments can transfer the mechanical force throughout the composite material, such that the mechanical force changes a shape of the composite material reversibly and repeatedly. |
| FILED | Thursday, November 02, 2023 |
| APPL NO | 18/500741 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/025 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2511/00 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/0618 (20210801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141979 | Mueller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Russell L. Mueller (Dallas, Texas); Charles H. Speller (Oak Point, Texas) |
| ABSTRACT | Systems and methods are described for shoulders that can be implemented on shafts in gear systems, such as a drive train. The shoulders, in combination with other components like bearings, or nuts, can help restrict movement of the shaft within the drive train. Use of the shoulders in various embodiments can avoid the need for grind reliefs in corners. Grind reliefs can help in prior art systems where machining or grinding is used at surfaces where raceways of bearings border shoulders that are integrated with the shaft. Grind reliefs create tight spaces where edge breaks are difficult to create. Press-fit shoulders, such as described herein, allow machining and edge break creation on the shaft prior to installation of the shoulder. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 17/979484 |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/36 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 19/525 (20130101) Gearing F16H 57/022 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141981 | Maxwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John N. Maxwell (Keller, Texas); Nick J. Jones (Fort Worth, Texas) |
| ABSTRACT | Methods and apparatuses are described to increase emissivity within a gearbox. Loss-of-lube conditions can cause a gearbox in a vehicle to quickly heat up and fail, which could lead to loss of aircraft and/or life. Surface treatments within a gearbox, such as black paint, black oxide coatings, shot-peening, and others, can increase emissivity within the gearbox. The increased emissivity can increase heat transfer via radiation, leading to longer operational capabilities during loss-of-lube conditions. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 17/979447 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/12 (20130101) Gearing F16H 57/032 (20130101) F16H 57/0412 (20130101) Original (OR) Class F16H 2057/02043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142208 | Denesha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Paul Denesha (Bedford, Indiana); Michael L. Holzmeyer (Bloomfield, Indiana); James G. Buechler (Jasper, Indiana); Eric S. Gilham (Otwell, Indiana); Anthony Berger (Jasper, Indiana) |
| ABSTRACT | Provided is an ammunition canister system that includes a can with an open interior and a mounting plate. A first and a second interior divider form three interior ammunition storage bays, while a three-to-one transition feed tray transitions belted ammunition contained in the bays to a single feed chute. The base of the can further includes loading pins, quick release locks, and lock pins, while the mounting plate includes mounting apertures, loading guides, quick release lock pin receiving apertures, and pin accepting apertures on the second side. The loading pins interface with the loading guides, the quick release locks interface with the quick release lock pin receiving apertures, and the lock pins interface with the pin accepting apertures to secure the ammunition canister to the mounting plate. The mounting plate enables the can to be mounted to the deck of helicopter or another vehicle. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/374921 |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 39/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142379 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peng Chen (Ithaca, New York); Rong Ye (Ithaca, New York); Xiangcheng Sun (Rochester, New York); Xianwen Mao (Singapore, Singapore) |
| ABSTRACT | Methods and systems for reaction product imaging. In various examples, a method is used to image fluorogenic reaction product(s), such as, for example, fluorogenic polymerization product(s) or the like. In various examples, a method of imaging a fluorescent polymerization product comprises a photo-uncaging reaction, a fluorogenic polymerization, and obtaining one or more fluorescence image(s) of one or more of the fluorescent polymerization product(s). In various examples, a system for imaging a fluorescent polymerization product comprises a first laser suitable to initiate a photo-uncaging reaction; and a second laser suitable to obtain one or more fluorescent image(s) of fluorogenic reaction product(s) and the product(s) is/are disposed on a substrate. In various examples, a method and/or a system is used to determine a polymer sequence, reaction kinetics, reaction dynamics, catalysis cooperativity between spatially distinct sites, molecular adsorption onto a surface, or the like. |
| FILED | Friday, May 05, 2023 |
| APPL NO | 18/144022 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 132/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) Original (OR) Class G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240142382 — METHODS AND COMPOSITIONS FOR CALIBRATED LABEL-FREE SURFACE-ENHANCED RAMAN SPECTROSCOPY
| US 20240142382 | ZHOU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wei ZHOU (Blacksburg, Virginia); Wonil NAM (Blacksburg, Virginia) |
| ABSTRACT | In one aspect, the disclosure relates to methods of label-free surface-enhanced Raman spectroscopy (SERS) comprising plasmonically enhanced electronic Raman scattering (ERS) signals from metal nanostructures as an internal calibration standard to improve multivariate analysis of living biological systems, and the uses of the methods therein. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/280452 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Original (OR) Class G01N 33/4833 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142686 | RUBIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Noah A. RUBIN (Cambridge, Massachusetts); Federico CAPASSO (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides an optical component, which may be a metasurface grating, including (a) a substrate; and (b) an array of subwavelength-spaced phase-shifting elements, which are tessellated on the substrate to produce, when illuminated with a polarized incident light, a diffracted light beam with a distinct polarization state for each of a finite number of diffraction orders, wherein the finite number is 2 or more. |
| FILED | Monday, December 04, 2023 |
| APPL NO | 18/528721 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) Optical Elements, Systems, or Apparatus G02B 5/3025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142758 | Hoover et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADVANCED OPTICAL TECHNOLOGIES, INC. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | ADVANCED OPTICAL TECHNOLOGIES, INC. (Albuquerque, New Mexico) |
| INVENTOR(S) | Brian G. Hoover (Tijeras, New Mexico); Jonathan H. Turner (Albuquerque, New Mexico) |
| ABSTRACT | A polarimeter and a method of analyzing and imaging microstructural material orientation of a polished reflective sample are disclosed. The polarimeter, which is a partial Mueller-matrix polarimeter (pMMP), accesses multiple independent polarization channels by employing two independent polarization modulators configured to switch serially among multiple independent settings, wherein the combination of the settings of the first and second polarization modulators defines an independent polarization channel, and wherein an imaging detector produces a set of polarization images that are synchronized with the channels formed by the polarization modulators; and wherein a processor connected with a memory executes a classification algorithm stored in the memory that maps the set of polarization images to one or more material orientation images by mapping the set of values for each detector pixel corresponding to the set of polarization images to a value of material orientation at each pixel coordinate using a model. The invention can thereby create material microstructural orientation images of diverse anisotropic materials, for instance polymer domains, fiber bundles or plys, and crystalline grains. |
| FILED | Monday, January 08, 2024 |
| APPL NO | 18/407012 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 2021/8477 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0068 (20130101) G02B 21/0092 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142764 | NOTCUTT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STABLE LASER SYSTEMS, INC. (Boulder, Colorado) |
| ASSIGNEE(S) | STABLE LASER SYSTEMS, INC. (Boulder, Colorado) |
| INVENTOR(S) | Mark NOTCUTT (Boulder, Colorado); Josue DAVILA-RODRIGUEZ (Boulder, Colorado); William David LEE (Boulder, Colorado) |
| ABSTRACT | Methods and systems for controlling and maintaining the pressure in an ultra-stable optical resonance cavity are disclosed herein. A method for controlling and maintaining the pressure in an ultra-stable optical resonance cavity, for example, comprises providing an ultra-stable optical system housed in a vacuum housing enclosure and a pumping system in communication with the vacuum housing for maintaining a pressure in the vacuum housing less than 1×10−6 Torr. The pumping system may comprise combination pumping achieved with the simultaneous use of a getter pump and an ion pump that provide passive and active pumping, respectively. The pumping system may also comprise passive pumping only with a getter vacuum pump only. The present invention, disclosed herein, achieves passive, power-free pumping in ultra-stable laser systems thereby enhancing the portability of such systems. |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/493550 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240143151 | Bennett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Bennett (Raleigh, North Carolina); Robert Karl (Raleigh, North Carolina); Warren Campbell (Apex, North Carolina) |
| ABSTRACT | Systems, methods, and devices for a graphical user interface (GUI) builder for a heads-up display. A user may interface with the GUI builder to create a profile. The profile comprises a logical ordering of one or more screens, with each screen comprising at least one widget. The widgets may be configured to display data on the screen and may be configurable by the user. Profiles may be shared with other users. A software development kit may be provided for developing custom widgets. The heads-up display may be on a night vision device. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 17/977940 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0149 (20130101) Electric Digital Data Processing G06F 3/14 (20130101) G06F 3/0481 (20130101) G06F 3/04845 (20130101) G06F 3/04847 (20130101) Original (OR) Class G06F 8/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240143689 | Jha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susmit Jha (Redwood City, California); Adam Derek Cobb (Washington, District of Columbia); Anirban Roy (San Francisco, California); Daniel Elenius (Redwood City, California); Patrick Denis Lincoln (Woodside, California) |
| ABSTRACT | In an example, a method of designing a system or architecture includes, receiving a plurality of parameter values and a set of requirements for a plurality of objective functions related to a design problem; compressing the plurality of parameters to generate a latent representation; forward processing, with one or more Invertible Neural Networks (INNs), the latent representation to generate a plurality of objective values corresponding to the plurality of the objective functions; inverse processing the plurality of objective values; and generating, based on the latent representation, a plurality of solutions to the design problem that satisfy the set of requirements for the plurality of objective functions. |
| FILED | Wednesday, October 18, 2023 |
| APPL NO | 18/489777 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/11 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145907 | Finkel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Finkel (Baltimore, Maryland); Margo Staruch (Alexandria, Virginia); Thomas Mion (Ellicott City, Maryland); Alex Moser (Fort Washington, Maryland) |
| ABSTRACT | The present invention provides a magnetoelectric multiferroic, time-variable magnetic field transmitter based upon a resonant structure capable of enhancing the transmitted field at the structural resonant frequency. This transmitter utilizes a single crystal piezoelectric as the source of mechanical excitations with a laminated transduction element to reduce eddy currents in the magnetostrictive material thereby reducing losses at higher frequencies. The structural resonance frequency can be tuned by adjusting the size of the masses, position and strength of bias magnets, pre-stress conditions and physical parameters of the transduction column elements. |
| FILED | Thursday, November 02, 2023 |
| APPL NO | 18/386402 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/36 (20130101) Original (OR) Class H01Q 9/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145932 | Williams |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Radar Corporation (Belmont, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jon Williams (San Francisco, California) |
| ABSTRACT | Microwave radar systems using compact form factor devices are described. Examples of such devices include a “folded” beamformer. The beamformer includes: a linear array of microwave antennas; a principal plane including: a Rotman lens; a first set of coplanar microwave waveguides; and a second set of coplanar microwave waveguides; and a series of one or more first planes parallel to the principal, each first plane including the first set of waveguides. Each plane of the beamformer includes one or more sets of miter bends, each set of miter bends configured to redirect waveguides of the first or second set. The beamformer can be configured for use in a radar system, either as a receiver (RX) beamformer, a transmitter (TX) beamformer, or as a combined transceiver (TRX) beamformer. The radar system can also include a second beamformer for receiving and transmitting using two separate beamformers. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/240782 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/032 (20130101) G01S 13/426 (20130101) G01S 2013/0263 (20130101) Antennas, i.e Radio Aerials H01Q 3/36 (20130101) H01Q 15/06 (20130101) Original (OR) Class H01Q 17/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240146416 | O'Keeffe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Conor O'Keeffe (Cork, Ireland); Anthony Kelly (Limerick, Ireland); Adam Herrmann (Dublin, Ireland); Finbarr O'Regan (Innishannon, Ireland); Sundar Krishnamurthy (Dublin, California); Amy Whitcombe (Saratoga, California); Ricard Menchon Enrich (Dublin, Ireland); Deepak Dasalukunte (Beaverton, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Conor O'Keeffe (Cork, Ireland); Anthony Kelly (Limerick, Ireland); Adam Herrmann (Dublin, Ireland); Finbarr O'Regan (Innishannon, Ireland); Sundar Krishnamurthy (Dublin, California); Amy Whitcombe (Saratoga, California); Ricard Menchon Enrich (Dublin, Ireland); Deepak Dasalukunte (Beaverton, Oregon) |
| ABSTRACT | A method for calibrating an optical transceiver. The method can include configuring optical switches to enable routing at least one output signal of modulator circuitry operably coupled to a first receive path of a coherent optical transceiver. The method can include configuring the input to at least one modulator to generate at least one first stimulus signal. The method can include configuring a path from the first receiver analog-to-digital converter to an adaptive algorithm circuitry. The method can include adapting at least one bias setting of a photodiode associated with the first receiver in response to at least one first stimulus detected at the first receiver analog-to-digital converter to an adaptive algorithm circuitry. The method can include determining an optimum value of a photodiode associated with the first receiver. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 17/979234 |
| CURRENT CPC | Transmission H04B 10/40 (20130101) Original (OR) Class H04B 10/112 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240146500 | Krishnamurthy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sundar Krishnamurthy (Dublin, California); Deepak Dasalukunte (Beaverton, Oregon); Conor O'Keeffe (Cork, Ireland); Finbarr O'Regan (Innishannon, Cork, Ireland); Amy Whitcombe (Saratoga, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sundar Krishnamurthy (Dublin, California); Deepak Dasalukunte (Beaverton, Oregon); Conor O'Keeffe (Cork, Ireland); Finbarr O'Regan (Innishannon, Cork, Ireland); Amy Whitcombe (Saratoga, California) |
| ABSTRACT | A clock data recovery (CDR) apparatus can include an interpolator circuitry to interpolate an input received signal and to generate an output signal removing the sampling clock offsets. The apparatus can include timing error detector (TED) circuitry coupled to process the output signal and to provide a timing error as feedback to the interpolator circuitry, the timing error being adjusted by gain factors used in at least one of an automatic gain control (AGC) circuitry and an orthogonalization circuitry. The apparatus can include loop filter (LF) circuitry to filter the timing error to remove noise effects. The apparatus can include numerically controlled oscillator (NCO) circuitry to adjust for a basepoint and fractional interval used to adjust resampling coefficients within the interpolator circuitry. |
| FILED | Tuesday, November 01, 2022 |
| APPL NO | 17/978582 |
| CURRENT CPC | Transmission H04B 10/118 (20130101) H04B 10/07955 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0029 (20130101) H04L 7/048 (20130101) H04L 7/0075 (20130101) Original (OR) Class H04L 7/0331 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240146547 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Young L Kim (West Lafayette, Indiana); Jung Woo Leem (West Lafayette, Indiana) |
| ABSTRACT | A method of generating a physically unclonable function (PUF) for pharmaceutical authentication is disclosed which includes generating an edible (PUF), affixing the edible PUF onto a pharmaceutical in a random distribution, and generating a crypto-graphic key based on the randomly distributed and affixed edible PUF. The present disclosure generally relates to counterfeit measures, and in particular, to an arrangement concerning an edible unclonable function counterfeit measure. |
| FILED | Saturday, August 15, 2020 |
| APPL NO | 17/768289 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/42 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/018 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3278 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240147025 | Graciarena et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Martin Graciarena (Belmont, California); John Cadigan (San Diego, California); Alan Taitz (Menlo Park, California) |
| ABSTRACT | In general, the disclosure describes techniques for obtaining, by a computing system, a content item and a purported source for the content item, wherein the content item may include multimodal data. The techniques may further include generating, by the computing system, a plurality of modality feature vectors representative of the multimodal data, wherein each of the generated modality feature vectors has a different, corresponding modality feature. The techniques may further include mapping, by the computing system, the generated modality feature vectors based on a statistical distribution associated with the purported source. The techniques may further include determining, by the computing system, a score based on the mapping. The techniques may further include outputting, by the computing system and based on the score, an indication of whether the content item originated from the purported source. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/471171 |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 21/83 (20130101) Original (OR) Class H04N 21/814 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240147626 | FULLER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Jerome K. FULLER (Van Nuys, California); Todd Fillmore SHEERIN (Beverly Hills, California) |
| ABSTRACT | A dynamic flex circuit includes a plurality of hole sets arranged along the dynamic flexible circuit. The dynamic flex circuit also includes a plurality of actuator wires coupled to the dynamic flexible circuit by way of intertwining each of the plurality of actuator wires through each hole set in the plurality of hole sets arrange along the dynamic flexible circuit. Each of the plurality of actuator wires are configured to impart a motion onto the dynamic flexible circuit depending on the amount of heat applied to each of the plurality of actuator wires. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 18/052165 |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/118 (20130101) H05K 1/189 (20130101) Original (OR) Class H05K 3/363 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240139299 | Serda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rita E. Serda (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico); Jacob Ongudi Agola (Albuquerque, New Mexico); Jimin Guo (Albuquerque, New Mexico); Sarah Adams (Albuquerque, New Mexico) |
| ABSTRACT | A silicified cell replica includes a silicified cell or a silicified subcellular fragment. The silicified cell replica may be used to induce an immunological response, treat a bacterial infection, or treat a patient with cancer. |
| FILED | Thursday, January 04, 2024 |
| APPL NO | 18/404430 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/6006 (20130101) A61K 2039/55594 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139705 | GUPTA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SUSTAERA INC. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raghubir Prasad GUPTA (Durham, North Carolina); Cory Elliott SANDERSON (Wendell, North Carolina); Shaojun James ZHOU (Cary, North Carolina); Shantanu AGARWAL (Durham, North Carolina); Tyson Lee LANIGAN-ATKINS (Durham, North Carolina); Arnold Chris TOPPO (Raleigh, North Carolina); Jian Ping SHEN (Chapel Hill, North Carolina) |
| ABSTRACT | A structured material assembly for removing CO2 from a gas, comprises a substrate, a sorbent for adsorbing CO2 from the gas, and a desorption material integrated into the structured material assembly, which is responsive to inputted energy to generate heat to desorb CO2 from the sorbent. The CO2-containing gas may comprise ambient air. |
| FILED | Wednesday, March 09, 2022 |
| APPL NO | 18/280509 |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/82 (20130101) B01D 53/96 (20130101) B01D 2253/25 (20130101) B01D 2253/104 (20130101) B01D 2257/504 (20130101) B01D 2258/06 (20130101) B01D 2259/40096 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/08 (20130101) B01J 20/20 (20130101) Original (OR) Class B01J 20/043 (20130101) B01J 20/324 (20130101) B01J 20/3204 (20130101) B01J 20/3236 (20130101) B01J 20/3433 (20130101) B01J 20/3483 (20130101) B01J 20/28011 (20130101) B01J 20/28045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139817 | LUO |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | YUEFENG LUO (NORTH AUGUSTA, South Carolina) |
| ABSTRACT | In one aspect, a system for building three-dimensional objects includes a powder source containing a powder material and a cylindrically-shaped substrate rotatable about a rotational axis. The substrate is provided in operative association with the powder source such that rotation of the substrate relative to the powder source about the rotational axis results in a layer of powder material being deposited relative to at least a portion of an outer surface of the substrate. The system also includes a fusion/binder source configured to cause the powder material deposited relative to the substrate to be fused or adhered together, and a computing system configured to control an operation of the fusion/binder source as the substrate is rotated about the rotational axis to generate a three-dimensional object relative to the outer surface of the substrate. |
| FILED | Thursday, October 27, 2022 |
| APPL NO | 17/974791 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/14 (20210101) B22F 10/85 (20210101) B22F 12/37 (20210101) Original (OR) Class B22F 12/90 (20210101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) B29C 64/245 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139818 | Zelina |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua N. Zelina (Idaho Falls, Idaho) |
| ABSTRACT | An atomization device includes a container and an atomization system. The container is sized and configured to be located within a build chamber of an additive manufacturing apparatus. The container includes a container opening in a top thereof. The container opening is sized and configured to receive an energy source of the additive manufacturing apparatus extended through the container opening or sized and configured to permit passage of energy from the energy source through the container opening. The atomization system includes a target substrate support including a device to vibrate the target substrate positioned within the container and is configured to cooperate with the additive manufacturing apparatus and utilize the energy to atomize a target substrate within the container. An additive manufacturing system and a method for atomizing a target substrate are also disclosed. |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/493313 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/082 (20130101) B22F 12/50 (20210101) Original (OR) Class B22F 2009/0848 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140025 | Sauers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aaron Sauers (Aurora, Illinois); Robert Kephart (Pioneer, California) |
| ABSTRACT | A method and system for in situ cross-linking of polymers, Bitumen, and other materials to produce arbitrary functional or ornamental three-dimensional features using electron beams provided by mobile accelerators comprises defining a desired pattern for imparting on a target area, mapping the target area, defining at least one discrete voxel in the target area according to the desired pattern to be imparted on the target area, assigning an irradiation value to each of the at least one discrete voxels, and delivering a dose of irradiation to each of the at least one discrete voxels according to the assigned irradiation value. |
| FILED | Thursday, December 14, 2023 |
| APPL NO | 18/540152 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/135 (20170801) Original (OR) Class B29C 64/264 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/24 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Construction Of, or Surfaces For, Roads, Sports Grounds, or the Like; Machines or Auxiliary Tools for Construction or Repair E01C 11/005 (20130101) E01C 23/14 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/06 (20130101) H01J 37/305 (20130101) H01J 37/1472 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140052 | AITHARAJU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Venkateshwar R. AITHARAJU (Troy, Michigan); Erik Brandon GOLM (Sterling Heights, Michigan); Xiaosong HUANG (Novi, Michigan) |
| ABSTRACT | A method for fabricating a composite panel includes providing a preform including a peripheral edge portion and a central portion. The central portion has a first thickness, the peripheral edge portion has a second thickness that is greater than the first thickness, and a first step is arranged between the central portion and the peripheral edge portion. The method includes providing a tool including a binder defining a second step, an upper punch, and a lower tool; arranging the preform between the binder and the upper punch and the lower tool; shaping the preform using the tool; and injection molding the preform in the tool to create the composite panel. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 17/977083 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0005 (20130101) B29C 45/80 (20130101) B29C 45/14008 (20130101) B29C 45/14221 (20130101) B29C 70/06 (20130101) B29C 70/345 (20130101) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140805 | Gajdardziska-Josifovska et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | COnovate, Inc. (Shorewood, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marija Gajdardziska-Josifovska (Fox Point, Wisconsin); Marvin Schofield (Milwaukee, Wisconsin); Yakov Kutsovsky (Arlington, Massachusetts); Carol J. Hirschmugl (Shorewood, Wisconsin) |
| ABSTRACT | A composition of graphene-based nanomaterials characterized by at least one area of one atomic layer of graphene monoxide, wherein at least a portion of oxygen molecules present in the graphene monoxide are incorporated into specific crystalline structural moieties, methods of making the same, electrodes in electrochemical devices incorporating the same, and compositions of lithium and graphene monoxide containing materials that result from cycling said electrodes. |
| FILED | Thursday, September 14, 2023 |
| APPL NO | 18/467034 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/198 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140987 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Hong Liu (Corvallis, Oregon); Luguang Wang (Corvallis, Oregon); Kevin Linowski (Corvallis, Oregon) |
| ABSTRACT | Single cell protein (SCP) is produced by applying a voltage to a microbial electrolysis cell (MEC) under anaerobic conditions for a period of time, whereby SCP is produced. The MEC includes a cathode comprising a hydrogen evolution reaction material, an anode comprising a biofilm on a carbon support, an electrolyte comprising carbon, nitrogen, and phosphorus, and a Methanococcus or Acetobacterium species in the electrolyte. |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/493255 |
| CURRENT CPC | Peptides C07K 1/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141097 | Bae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chulsung Bae (Cohoes, New York); Woo-Hyung Lee (Troy, New York) |
| ABSTRACT | Embodiments of the invention relate to a novel class of polymers with superior mechanical properties and chemical stability, as compared to known polymers. These polymers are particularly well suited for use in anion exchange membranes (AEMs), including those employed in fuel cells. Novel methods for the manufacture of these polymers are also described. |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/493772 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 29/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 10/00 (20130101) C08G 61/02 (20130101) Original (OR) Class C08G 2261/20 (20130101) C08G 2261/45 (20130101) C08G 2261/124 (20130101) C08G 2261/146 (20130101) C08G 2261/312 (20130101) C08G 2261/332 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) C09D 165/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 13/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1004 (20130101) H01M 8/1039 (20130101) H01M 8/1072 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141127 | KETUSKY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (Aiken, South Carolina); NICHOLAS M. MARSHALLL (GRANITEVILLE, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | EDWARD T. KETUSKY (BEECH ISLAND, South Carolina); MARK D. KRANJC (AIKEN, South Carolina); JAMES M. SHULER (GERMANTOWN, Maryland); NICHOLAS M. MARSHALL (GRANITEVILLE, South Carolina) |
| ABSTRACT | Disclosed are foamable compositions that can be particularly beneficial for foam-in-place packaging purposes. The foamable compositions can be reacted to form a polyurethane foam that can be utilized to secure packaging contents inside a transport packages, and that at a later time can be readily decomposed at low degradation temperatures, e.g., about 90° C. or less. The polyurethane foam can also act as a sink for hydrogen radicals and as such can be utilized for transport of high energy emitting materials, e.g., γ-radiating materials. |
| FILED | Thursday, October 13, 2022 |
| APPL NO | 17/965297 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/18 (20130101) B32B 2266/0278 (20130101) B32B 2439/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/14 (20130101) C08G 18/72 (20130101) C08G 18/6666 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/125 (20130101) Original (OR) Class C08J 2203/10 (20130101) C08J 2375/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141368 | Kausch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rhode Island Board of Trustees (Kingstown, Rhode Island); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Albert P. Kausch (Charlestown, Rhode Island); Markita Landry (Berkeley, California) |
| ABSTRACT | Described herein are methods and compositions for direct genome editing in vivo in plants by targeting cells in the shoot apical meristem. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/495731 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/8229 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141503 | Ertsgaard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Quantinuum LLC (Broomfield, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Todd Ertsgaard (Champlin, Minnesota); Adam Jay Ollanik (Boulder, Colorado); Todd Michael Klein (Wayzata, Minnesota); John Snyder (Edina, Minnesota); Ryan Patrick Shea (Elko New Market, Minnesota); Christopher Todd DeRose (Albuquerque, New Mexico); Michael Ryan Gehl (Tijeras, New Mexico) |
| ABSTRACT | A method of applying a dielectric coating on a structure array of a component of an electrical device includes applying a first layer of a first dielectric material on a structure array with an atomic layer deposition (ALD) process or a spin-on cladding process. The structure array has a plurality of features. The method may include applying a second layer of a second dielectric material on the first layer with an evaporation deposition process, a physical vapor deposition process (PVD), or a flux-controlled chemical vapor deposition (CVD) process. The first layer has a first thickness and the second layer has a second thickness that is greater than the first thickness. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498493 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/402 (20130101) C23C 16/45529 (20130101) C23C 28/04 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141519 | Toma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Francesca Maria Toma (Ann Arbor, Michigan); Guosong Zeng (Ann Arbor, Michigan); Tadashi Ogitsu (Ann Arbor, Michigan); Tuan Anh Pham (Ann Arbor, Michigan); The Regents of the University of Michigan (Ann Rbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Francesca Maria Toma (Berkeley, California); Tadashi Ogitsu (Dublin, California); Zetian MI (Ann Arbor, Michigan); Srinivas Vanka (Ann Arbor, Michigan); Guosong Zeng (Berkeley, California); Tuan Anh Pham (Livermore, California); Yixin Xiao (Ann Arbor, Michigan) |
| ABSTRACT | A method of fabricating a device includes providing a substrate of the device, forming a structure of the device, the structure being supported by the substrate, having a semiconductor composition, and including a surface, where nitrogen is present at the surface, and incorporating oxygen into the surface to form a stabilizing layer on the surface. Incorporating oxygen into the surface is implemented such that the stabilizing layer includes a uniform distribution of an oxynitride material |
| FILED | Monday, February 28, 2022 |
| APPL NO | 18/279181 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 11/052 (20210101) C25B 11/059 (20210101) C25B 11/087 (20210101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02175 (20130101) H01L 21/02241 (20130101) H01L 29/045 (20130101) H01L 29/401 (20130101) H01L 29/513 (20130101) H01L 29/518 (20130101) H01L 29/2003 (20130101) H01L 33/16 (20130101) H01L 33/32 (20130101) H01L 33/44 (20130101) H01L 2933/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141528 | Powell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam C. Powell (Newton, Massachusetts); David Dussault (Stoneham, Massachusetts); Matthew Earlam (Lakewood, Colorado); Aaron Tajima (Melrose, Massachusetts); Connor Raymes (San Francisco, California) |
| ABSTRACT | Method and apparatus are provided for efficient metal distillation, and for related primary product process. Vertically stacked and gravity-driven evaporators and condensers are employed to distill metals, such metals having different volatilities. A multiple-effect thermal system of magnesium and other volatile metals is used to efficiently distill and separate metals from multiple metal alloys. |
| FILED | Tuesday, October 03, 2023 |
| APPL NO | 18/376216 |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 7/004 (20130101) C22B 9/02 (20130101) C22B 26/22 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 3/04 (20130101) Original (OR) Class C25C 3/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141674 | Turnquist et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Norman Arnold Turnquist (Carlisle, New York); Christopher James Kenny (Schoharie, New York); Xiaopeng Li (Niskayuna, New York); Gregory Edward Cooper (Greenfield Center, New York); Biao Fang (Clifton Park, New York); Pascal Meyer (Burnt Hills, New York); Collin McKee Sheppard (Greenville, South Carolina); Ryan Eric Vogel (Greer, South Carolina) |
| ABSTRACT | The present disclosure is directed to embodiments of a tower structure with at least partially additively manufactured, stacked tower sections. Embodiments of the tower structure have a plurality of stacked tower sections, wherein at least one tower section of the plurality of stacked tower sections includes a wall element having one or more printed layers, and a base holding thereon the one or more printed layers. The present disclosure also is directed to a method of manufacturing a tower structure using a stacked tower sections and additive manufacturing. Embodiments of the method include forming a base of poured concrete or cast material, printing and depositing one or more printed layers to form a wall element, and stacking the plurality of tower sections to form the tower structure. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 17/977374 |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Scaffolding; Forms; Shuttering; Building Implements or Aids, or Their Use; Handling Building Materials on the Site; Repairing, Breaking-up or Other Work on Existing Buildings E04G 21/142 (20130101) Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 12/12 (20130101) E04H 12/342 (20130101) Original (OR) Class Wind Motors F03D 13/20 (20160501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142146 | KOZUBAL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric KOZUBAL (Superior, Colorado); Jason David WOODS (Boulder, Colorado) |
| ABSTRACT | A modular cold climate heat pump system which, in some embodiments includes a multi-segment heat exchanger. The modular cold climate heat pump system includes a heat pump module, a thermal energy storage module, and at least one end use module. Exemplary end uses include heating, ventilation, and air conditioning applications or domestic hot water heating. The thermal energy storage module may enable the heat pump module to continue operating even during temperatures below freezing. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/494306 |
| CURRENT CPC | Domestic- or Space-heating Systems, e.g Central Heating Systems; Domestic Hot-water Supply Systems; Elements or Components Therefor F24D 5/12 (20130101) F24D 17/02 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 25/005 (20130101) Original (OR) Class F25B 30/02 (20130101) F25B 40/02 (20130101) F25B 40/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142333 | Milholland |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Roger A Milholland (Sheridan, Illinois) |
| ABSTRACT | A portable, case-enclosed pressure test manifold, configured to support both pneumatic and hydrostatic pressure testing, and comprising a downstream fluid path (e.g., a system test gauge, a ball valve, a system test port, a system relief valve, and other components/piping) and an upstream fluid path (e.g., a low-pressure gauge, a high-pressure gauge, and various other components/piping). A regulator and/or the ball valve selectively operate the downstream fluid path, defining a hydrostatic pressure testing path, to receive a liquid; and the upstream fluid path in combination with the downstream fluid path, defining a pneumatic pressure testing path, to receive a gas. Manifold components are pressure rated based on use and are ASME Code B31.3 compliant. Properly rated flexible hoses connect with either of the pneumatic or the hydrostatic pressure testing paths of the manifold. The case includes parking receptables and a carrying handle configured to stow the hose during transport. |
| FILED | Thursday, January 11, 2024 |
| APPL NO | 18/410915 |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142688 | WARD |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | PATRICK A. WARD (AIKEN, South Carolina) |
| ABSTRACT | In one aspect, a system for collecting light directed through an architectural opening includes a plurality of optical fibers positioned within the architectural opening. A portion of light from a light source is absorbed by the plurality of optical fibers. One or more optical fibers of the plurality of optical fibers are configured to transmit the absorbed light to one or more light collection elements. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 17/979377 |
| CURRENT CPC | Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors F21S 11/002 (20130101) Optical Elements, Systems, or Apparatus G02B 6/0006 (20130101) Original (OR) Class G02B 6/0008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142689 | WARD |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (AIKEN, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | PATRICK A. WARD (AIKEN, South Carolina) |
| ABSTRACT | In one aspect, a system for collecting light directed through an architectural opening includes a plurality of optical fibers positioned within the architectural opening. A portion of light from a light source is absorbed by the plurality of optical fibers. One or more optical fibers of the plurality of optical fibers are configured to transmit the absorbed light to one or more light collection elements. |
| FILED | Wednesday, September 27, 2023 |
| APPL NO | 18/475428 |
| CURRENT CPC | Non-portable Lighting Devices; Systems Thereof; Vehicle Lighting Devices Specially Adapted for Vehicle Exteriors F21S 11/002 (20130101) Optical Elements, Systems, or Apparatus G02B 6/0006 (20130101) Original (OR) Class G02B 6/0008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142814 | Chatterjee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bikramjit Chatterjee (Livermore, California); Lars F. Voss (Livermore, California); Clint Frye (Oakland, California) |
| ABSTRACT | An optically addressable light valve comprises a first transparent conductor layer, a layer of liquid crystal, and a photoconductor comprising an ultrawide band gap (UWBG) semiconductor. The liquid crystal is between the first transparent conductor layer and the semiconductor photoconductor. The optically addressable light valve is configured to apply a voltage across the liquid crystal and the UWBG semiconductor. A second transparent conductor may be formed in the UWBG semiconductor in some configurations, and the voltage may be applied across the first and second transparent conductor. |
| FILED | Friday, December 15, 2023 |
| APPL NO | 18/542455 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/13439 (20130101) G02F 1/133385 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240143184 | Dugan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Keith Dugan (Richardson, Texas); Tony M. Brewer (Plano, Texas) |
| ABSTRACT | A system includes a host device, a memory device, and a command manager configured to reorder respective command responses for corresponding commands between the host device and the memory device. The command manager is further configured to receive a command response associated with a transaction identifier for each command. An index value for the command is written to a reordering queue. In response to a command response write for the command response, the index value from the reordering queue is read. The index value is written in an index update queue. A network write index update message is transmitted. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 17/979390 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0616 (20130101) Original (OR) Class G06F 3/0659 (20130101) G06F 3/0673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240144655 | De et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Debraj De (Knoxville, Tennessee); Rutuja Gurav (Riverside, California); Junchuan Fan (Knoxville, Tennessee); Gautam Thakur (Knoxville, Tennessee) |
| ABSTRACT | A prediction system harvests geo-tagged ground-level images through one or more algorithms. The system receives point of interest data representing structures or events and tags the geo-tagged ground-level images with a probability describing a classification. The system tags point of interest data with a hierarchical genre classification and encodes the tagged geo-tagged ground-level images as vectors to form nodes and edges in a proximity graph. The system encodes tagged points of interest data as similarity vectors to render more nodes and more edges on the proximity graph associated with the tagged geo-tagged ground-level images nodes by calculated semantic distances. The system splits the proximity graph into a training subgraph and a testing subgraph and trains a neural network by aggregating and sampling information from neighboring nodes within the training subgraph graph and validates through the testing subgraph. Training ends when a loss measurement is below a threshold. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/383633 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/764 (20220101) G06V 10/774 (20220101) Original (OR) Class G06V 10/776 (20220101) G06V 20/50 (20220101) G06V 20/70 (20220101) Pictorial Communication, e.g Television H04N 19/46 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240144904 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Evelyn N. Wang (Cambridge, Massachusetts); Gang Chen (Carlisle, Massachusetts); Xuanhe Zhao (Allston, Massachusetts); Elise M. Strobach (Clear Lake, Wisconsin); Bikramjit S. Bhatia (Cambridge, Massachusetts); Lin Zhao (Revere, Massachusetts); Sungwoo Yang (Chattanooga, Tennessee); Lee A. Weinstein (Somerville, Massachusetts); Thomas A. Cooper (Boston, Massachusetts); Shaoting Lin (Cambridge, Massachusetts) |
| ABSTRACT | Described herein are window retrofits including a monolithic silica aerogel slab having (i) an average haze value of <5% as calculated in accordance with ASTM standard D1003-13 and (ii) a U-factor of <0.5 BTU/sf/hr/° F., and a transparent polymer envelope sealed at an internal pressure of ≤1 atmosphere, wherein the monolithic silica aerogel slab is encapsulated in the transparent polymer envelope. The monolithic aerogel slab can have a transmittance>94% at 8 mm thickness. The window retrofit can be bonded to a glass sheet. |
| FILED | Tuesday, June 27, 2023 |
| APPL NO | 18/342339 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/12 (20130101) B32B 7/027 (20190101) B32B 9/045 (20130101) B32B 2255/10 (20130101) B32B 2255/20 (20130101) B32B 2305/026 (20130101) B32B 2307/54 (20130101) B32B 2307/72 (20130101) B32B 2307/102 (20130101) B32B 2307/304 (20130101) B32B 2307/412 (20130101) B32B 2307/546 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/24 (20130101) E06B 2009/2417 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/168 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145104 | LAHODA |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Edward J. LAHODA (Edgewood, Pennsylvania) |
| ABSTRACT | A cladding for housing enriched nuclear fuel in a nuclear fuel assembly is provided. The cladding comprises a base layer comprised of Zirconium alloy and a coating for the base layer. The base layer has a wall thickness of less than 1 millimeter. The coating comprises a primary layer comprised of Chromium or a Chromium alloy. The primary layer has a thickness in the range of about 5 to about 50 microns. A fuel rod for a nuclear reactor core and a method for producing a fuel rod are also provided. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 18/051925 |
| CURRENT CPC | Nuclear Reactors G21C 3/07 (20130101) Original (OR) Class G21C 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145108 | Downey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Calvin M. Downey (Idaho Falls, Idaho); Abdalla Abou Jaoude (Idaho Falls, Idaho); William C. Phillips (Idaho Falls, Idaho); Chuting Tan Tsai (Idaho Falls, Idaho); Gregory M. Core (Idaho Falls, Idaho); Stacey M. Wilson (Idaho Falls, Idaho); SuJong Yoon (Idaho Falls, Idaho); Kim B. Davies (Moore, Idaho) |
| ABSTRACT | A temperature-controlled irradiation system may include an outer containment and a sealed capsule disposed within the outer containment. The sealed capsule may be configured to contain a testing material within the sealed capsule. The system may further include a temperature sensor disposed within the sealed capsule. The temperature sensor may be configured to measure a temperature of the testing material. A pressure sensor may be disposed within the sealed capsule. The pressure sensor may be configured to measure an internal pressure of the sealed capsule. The system may include a heater disposed within the sealed capsule. The heater may be configured to control the temperature of the testing material. The heater may be immersed within the testing material. A gas gap is provided between the sealed capsule and the outer containment. The gas gap may be configured to control thermal conductivity between the sealed capsule and the outer containment. |
| FILED | Thursday, November 02, 2023 |
| APPL NO | 18/500934 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/4853 (20130101) Nuclear Reactors G21C 11/08 (20130101) G21C 17/112 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240145204 — Electron emission methods to generate electron beams with a narrow energy distribution
| US 20240145204 | Stibor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Stibor (San Francisco, California); Cameron Johnson (Oakland, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to electron emission. A method includes providing a nanotip field emitter. The nanotip field emitter includes a nanoprotrusion at a tip of the nanotip field emitter. The nanotip field emitter is cooled to a temperature. The temperature is about 80 Kelvin or lower. An electric field is applied between an extraction electrode and the nanotip field emitter to induce emission of electrons from the nanotip field emitter. |
| FILED | Thursday, October 19, 2023 |
| APPL NO | 18/490079 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 29/481 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145607 | SEWELL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Maxeon Solar Pte. Ltd. (Singapore, Singapore) |
| ASSIGNEE(S) | |
| INVENTOR(S) | RICHARD HAMILTON SEWELL (Los Altos, California); MATTHIEU MINAULT REICH (San Jose, California); ANDREA R. BOWRING (Mountain View, California); ARBAZ SHAKIR (Santa Clara, California); RYAN REAGAN (Hayward, California); MATTHEW MATSUMOTO (Pasadena, California) |
| ABSTRACT | Wire-based metallization and stringing techniques for solar cells, and the resulting solar cells, modules, and equipment, are described. In an example, a string of solar cells includes a plurality of back-contact solar cells, wherein each of the plurality of back-contact solar cells includes P-type and N-type doped diffusion regions. A plurality of conductive wires is disposed over a back surface of each of the plurality of solar cells, wherein each of the plurality of conductive wires is substantially parallel to the P-type and N-type doped diffusion regions of each of the plurality of solar cells. One or more of the plurality of conductive wires adjoins a pair of adjacent solar cells of the plurality of solar cells and has a relief feature between the pair of adjacent solar cells. |
| FILED | Friday, January 05, 2024 |
| APPL NO | 18/405720 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/188 (20130101) H01L 31/0504 (20130101) Original (OR) Class H01L 31/0516 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145663 | Ye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianchao Ye (Tracy, California); Alexander A. Baker (Pleasanton, California); Harry B. Radousky (San Leandro, California) |
| ABSTRACT | An active layer for a battery includes a cold-sprayed composite layer positioned above a substrate, where the composite layer comprises an active component, a conductive component, and a binder. The composite layer is formed from a solid-state material. A method of making a composite layer includes forming a composite layer on a substrate by cold spraying particles of a composite powder above the substrate. The composite powder includes an active component, a conductive component, and a binder. |
| FILED | Wednesday, October 18, 2023 |
| APPL NO | 18/381560 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/0407 (20130101) H01M 4/0419 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145745 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Twelve Benefit Corporation (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sichao Ma (Dublin, California); Sara Hunegnaw (Oakland, California); Ziyang Huo (Moraga, California); Kendra P. Kuhl (Oakland, California); Etosha R. Cave (Berkeley, California); Ashley D. Mishra (Danville, California); Edward Izett (Berkeley, California); Alvin Leung (San Francisco, California); Timothy A. Bekkedahl (Fremont, California) |
| ABSTRACT | Provided herein are methods for operating carbon oxide (COx) reduction reactors (CRR) and related apparatus. In some embodiments, the methods involve shutting off, reducing, or otherwise controlling current during various operation stages including hydration, break-in, normal operation, planned shut-offs, and extended shutoff or storage periods. |
| FILED | Friday, December 15, 2023 |
| APPL NO | 18/542508 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/23 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04574 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145801 | Xiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jie Xiao (Richland, Washington); Ran Yi (Richland, Washington); Bingbin Wu (Richland, Washington); Yujing Bi (Richland, Washington) |
| ABSTRACT | A solid-state method for recycling spent and/or scrap cathode material includes heating a cathode material comprising lithium nickel manganese cobalt oxide in an oxygen-containing atmosphere at a temperature T1 for an effective period of time t1 to convert the cathode material to a solid precursor, combining the solid precursor with a lithium compound, and heating the solid precursor and the lithium compound in an oxygen-containing atmosphere at a temperature T2 for an effective period of time t2 to form a product comprising monocrystalline lithium nickel manganese cobalt oxide having a formula LiNixMnyMzCo1-x-y-zO2, where M represents one or more dopant metals, x≥0.33, 0.01≤y<0.33, 0≤z≤0.05, and x+y+≤z 1.0. |
| FILED | Wednesday, October 26, 2022 |
| APPL NO | 17/974022 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/50 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/54 (20130101) Original (OR) Class H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240146115 | Babakhani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Hamed Rahmani (Belle Mead, New Jersey); Hidemasa Mitsui (Santa Clara, California) |
| ABSTRACT | Systems and methods for utilizing a small form-factor, wirelessly powered transceiver are disclosed. In one embodiment, a wireless powered transceiver includes a receive antenna configured to receive a receive signal, a transmit antenna configured to transmit a transmit signal, a power harvesting system including a rectifier circuit configured convert radio frequency energy from the receive signal into DC (direct current) voltage, and a power management unit (PMU) configured to set the operating mode and biasing condition of the receive and transmit circuitry blocks and provide DC voltage from the receive circuitry block to the transmit circuitry block to maintain a minimum voltage, a receiver circuitry block configured to provide energy from the receive signal to the power harvesting system, and a transmitter circuitry block including a data modulator circuit, the data modulator circuit configured to generate the transmit signal using DC voltage received from the power management unit. |
| FILED | Wednesday, December 20, 2023 |
| APPL NO | 18/391277 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) H02J 50/27 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240146188 | Pilawa-Podgurski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Robert Pilawa-Podgurski (Alameda, California); Zichao Ye (Santa Clara, California) |
| ABSTRACT | A multi-phase hybrid power converter architecture which provides high efficiency, high power density and high conversion ratios for non-isolated DC to DC power conversion. Hybrid converters are described in which a switched-capacitor network is interoperably merged with a switched-inductor network having multiple inductors, resulting in a circuit with reduced component count and in which soft-charging of the capacitors is performed. Multi-phase switching is utilized and includes a freewheeling state for output voltage regulation in which inductor current ramps down. The SC converter can be configured to provide various conversion ratios, such as 4-to-1, 6-to-1 and 8-to-1, and optimized for the needs of specific application. |
| FILED | Monday, November 06, 2023 |
| APPL NO | 18/502585 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/007 (20210501) H02M 1/0095 (20210501) H02M 3/07 (20130101) Original (OR) Class H02M 3/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20240138715 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Chung-Tse Michael Wu (New Brunswick, New Jersey); Yichao Yuan (New Brunswick, New Jersey) |
| ABSTRACT | Various embodiments comprise systems, methods, architectures, mechanisms and apparatus providing a super-regenerative oscillator (SRO) integrated metamaterial (MTM) leaky wave antenna (LWA) architecture suitable for use in radio frequency (RF) detecting, ranging (e.g., RADAR), and sensing systems/applications, such as a noncontact multi-target vital sign detection system. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/384056 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/1102 (20130101) A61B 5/1126 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240138768 | CHUN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Young Jae CHUN (Pittsburgh, Pennsylvania); Moataz Mohsen AH ELSISY (Pittsburgh, Pennsylvania); Woon-Hong YEO (Atlanta, Georgia); Robert HERBERT (Atlanta, Georgia) |
| ABSTRACT | An exemplary method and system are disclosed for a fully implantable soft-membrane electronic system that can provide the continuous monitoring of real-time or semi real-time measurements of strain and/or other mechanical properties, via electrical measurements such as capacitance, over an inductive coupling between the measurement system and the implanted device. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/278712 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/076 (20130101) A61B 5/02007 (20130101) A61B 5/4851 (20130101) A61B 5/6862 (20130101) Original (OR) Class A61B 2562/0261 (20130101) A61B 2562/0285 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/915 (20130101) A61F 2002/91566 (20130101) A61F 2210/0076 (20130101) A61F 2240/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240138918 | Feiner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Steven Feiner (New York, New York); Gabrielle Loeb (Wynnewood, Pennsylvania); Alon Grinshpoon (New York, New York); Shirin Sadri (San Clemente, California); Carmine Elvezio (Bellmore, New York) |
| ABSTRACT | Certain embodiments include a method for assisting a clinician in performing a medical procedure on a patient using augmented reality guidance. The method can include obtaining a three-dimensional model of an anatomic part of the patient. The method can also include aligning the three-dimensional model with data to form augmented reality guidance for the medical procedure. In addition, the method can include presenting the augmented reality guidance to the clinician during the medical procedure using an augmented reality three-dimensional display. |
| FILED | Monday, May 22, 2023 |
| APPL NO | 18/321450 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 2034/107 (20160201) A61B 2034/108 (20160201) Electric Digital Data Processing G06F 3/167 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 19/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139380 | Mendez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President And Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keegan Mendez (Cambridge, Massachusetts); Ellen Roche (Cambridge, Massachusetts); Connor Verheyen (Boston, Massachusetts); Jennifer Lewis (Cambridge, Massachusetts); Markus Horvath (Somerville, Massachusetts); Sophie Wang (Boston, Massachusetts); Sebastien Uzel (Cambridge, Massachusetts) |
| ABSTRACT | Viscoelastic hydrogel microparticles are used for repair of tissue defects and injuries or filling and occlusion of anatomical structures. These are administered as a microparticle suspension using a catheter, syringe, steerable catheter tip, or comparable technology into the site, where they can be further stabilized by crosslinking or sealing, or through incorporation of a support or encapsulating structure. Materials and methods for solidifying, stabilizing and sealing these materials can be used that are also biocompatible and easily deployed with catheters in the body. The micron sized interstitial spacing provides a scaffold for ingrowth and migration of cells into the gel matrices. |
| FILED | Thursday, May 04, 2023 |
| APPL NO | 18/312492 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 2400/06 (20130101) A61L 2430/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240139811 | Kou |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sindo Kou (Madison, Wisconsin) |
| ABSTRACT | A device and method are provided for evaluating the susceptibility of hot cracking in an additive manufacturing process. A first end of a substrate is interconnected to a base and one of the base and a deposition device is moved in a first direction and the second end of the substrate is pulled. A powder is dispensed at a selected rate and an energy bean having an adjustable power density is direct at the powder to melt the powder to form a material which is deposited as a layer of a material on the substrate. During the deposition process or during the deposition of the material on a subsequent substrate, one or more parameters/conditions are varied to determine the point at which hot cracking occurs during the deposition process. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 17/976269 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/25 (20210101) Original (OR) Class B22F 10/85 (20210101) B22F 10/362 (20210101) B22F 12/30 (20210101) B22F 12/226 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140805 | Gajdardziska-Josifovska et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COnovate, Inc. (Shorewood, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marija Gajdardziska-Josifovska (Fox Point, Wisconsin); Marvin Schofield (Milwaukee, Wisconsin); Yakov Kutsovsky (Arlington, Massachusetts); Carol J. Hirschmugl (Shorewood, Wisconsin) |
| ABSTRACT | A composition of graphene-based nanomaterials characterized by at least one area of one atomic layer of graphene monoxide, wherein at least a portion of oxygen molecules present in the graphene monoxide are incorporated into specific crystalline structural moieties, methods of making the same, electrodes in electrochemical devices incorporating the same, and compositions of lithium and graphene monoxide containing materials that result from cycling said electrodes. |
| FILED | Thursday, September 14, 2023 |
| APPL NO | 18/467034 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/198 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140826 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts); Providence College (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yi Zheng (Canton, Massachusetts); Yanpei Tian (Boston, Massachusetts); Xiaojie Liu (Boston, Massachusetts); Yinsheng Wan (Lincoln, Rhode Island) |
| ABSTRACT | A carbonized manure photothermal evaporator derived from naturally abundant farm waste has high solar absorptance, effective water transportation, and rapid salt dissipation. It achieves high evaporation under 1-sun irradiance and is recyclable, durable, and cost-effective for use in energy-efficient solar-driven interfacial desalination. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 18/280865 |
| CURRENT CPC | Separation B01D 1/0035 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/14 (20130101) Original (OR) Class C02F 1/048 (20130101) C02F 2103/08 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 10/13 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140882 | Sotiriou-Leventis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Chariklia Sotiriou-Leventis (Rolla, Missouri); Nicholas Leventis (Worcester, Massachusetts); Rushi Soni (Rolla, Missouri); Vaibhav Edlabadkar (Rolla, Missouri); Parwani Rewatkar (Hillsboro, Oregon); ABM Shaheen ud Doulah (Rolla, Missouri) |
| ABSTRACT | Novel methods of synthesizing amorphous carbon and graphitic carbon aerogels are provided. The carbon aerogels produced by these methods are highly porous, monolithic carbon aerogels and are extremely robust. Specifically, the amorphous carbon aerogels have high surface areas and large micropore volumes. Due to these extraordinary properties, these aerogels possess high carbon dioxide (CO2) sorption capacities and are highly selective towards CO2 versus other gases, such as H2 and N2. As a result, the amorphous carbon aerogels can be used to effectively capture or remove CO2 from the air and/or from flue gases. Furthermore, the graphitic carbon aerogels notably have high graphite content, crystallite size, and graphite quality, of which are comparable to those of commercial graphite. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 18/554074 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 38/0022 (20130101) Original (OR) Class C04B 2235/48 (20130101) C04B 2235/5409 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/583 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140974 | Masson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio University (Athens, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Masson (Athens, Ohio) |
| ABSTRACT | The present disclosure concerns cucurbit[n]uril (CB) complexes of cucurbit[8]uril (CB[8]) and/or cucurbit[7]uril (CB[7]) that secure or host platinum conjugated terpyridines. The platinum center can further secure a protein through the thiol of a cysteine or an imidazole of a histidine therein. Additional CBs can secure the peptide through phenyl side chains. CB[8] will secure a dimer of platinum-terpyridines in a head-to-head alignment or a peptide dimer through a head-to-tail alignment. The application of multiple CBs allows for varying CB complex geometries. Also contemplated are methods of using the platinum-terpyridines to selectively bind cysteine rich proteins, such as cysteine proteases. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 18/554869 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6949 (20170801) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0093 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/506 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141125 | Leventis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aerogel Technologies, LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Aerogel Technologies, LLC (Boston, Massachusetts) |
| INVENTOR(S) | Nicholas Leventis (Rolla, Missouri); Chariklia Sotiriou-Leventis (Rolla, Missouri); Sudhir Mulik (North Wales, Pennsylvania) |
| ABSTRACT | Porous three-dimensional networks of polyurea and porous three-dimensional networks of carbon and methods of their manufacture are described. In an example, polyurea aerogels are prepared by mixing an triisocyanate with water and a triethylamine to form a sol-gel material and supercritically drying the sol-gel material to form the polyurea aerogel. Subjecting the polyurea aerogel to a step of pyrolysis may result in a three dimensional network having a carbon skeleton, yielding a carbon aerogel. The density and morphology of polyurea aerogels can be controlled by varying the amount of isocyanate monomer in the initial reaction mixture. A lower density in the aerogel gives rise to a fibrous morphology, whereas a greater density in the aerogel results in a particulate morphology. Polyurea aerogels described herein may also exhibit a reduced flammability. |
| FILED | Thursday, May 18, 2023 |
| APPL NO | 18/319538 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/00 (20170801) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/18 (20130101) C08G 18/302 (20130101) C08G 18/792 (20130101) C08G 2110/0091 (20210101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/02 (20130101) Original (OR) Class C08J 2205/026 (20130101) C08J 2375/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141368 | Kausch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Rhode Island Board of Trustees (Kingstown, Rhode Island); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Albert P. Kausch (Charlestown, Rhode Island); Markita Landry (Berkeley, California) |
| ABSTRACT | Described herein are methods and compositions for direct genome editing in vivo in plants by targeting cells in the shoot apical meristem. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/495731 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/8229 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141403 | Schepartz Shrader et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alanna Schepartz Shrader (Berkeley, California); Sebasthian Santiago González (Berkeley, California) |
| ABSTRACT | Recombinant proteins comprising a non-canonical amino acid with high yield and high fidelity are made by expressing the protein in an engineered Vibrio natriegens strain containing an orthogonal translation system comprising an orthogonal aminoacyl tRNA synthetase that charges the non-canonical amino acid onto the orthogonal cognate tRNA. |
| FILED | Thursday, November 30, 2023 |
| APPL NO | 18/523908 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 9/1247 (20130101) C12N 15/74 (20130101) C12N 2800/101 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class Enzymes C12Y 207/07006 (20130101) C12Y 601/01007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141414 | Jung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jaeyoung K. Jung (Evanston, Illinois); Khalid K. Alam (Evanston, Illinois); Julius B. Lucks (Evanston, Illinois) |
| ABSTRACT | Disclosed are compositions, systems, kits, and methods for detecting an analyte or target molecule in a sample by regulated in vitro transcription. The compositions, systems, kits, and methods typically comprise and/or utilize one or more components selected from: (a) an RNA polymerase; (b) an allosteric transcription factor (aTF), wherein the aTF binds an analyte or target molecule as a ligand; (c) an engineered transcription template; (d) a dsDNA signal gate molecule; and/or any combination thereof. |
| FILED | Monday, February 28, 2022 |
| APPL NO | 18/548175 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141545 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brandeis University (Waltham, Massachusetts); The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Benjamin Rogers (Watertown, Massachusetts); Alexander Hensley (Waltham, Massachusetts); William M. Jacobs (New York, New York) |
| ABSTRACT | A two-step process is provided for forming large photonic single crystals of about 0.1 millimeter and greater via DNA coated colloidal particles. The two-step process generally include decoupling the nucleation and growth steps. In particular, DNA colloidal particles are partitioned in nanoliter droplets formed in a water in oil emulsion using microfluidics. Once a crystal nucleates within a droplet, depletion of particles occurs as the crystal grows inhibit formation of more crystals within the droplet. A small number of droplets containing these seed crystals are then mixed with droplets containing weak DNA coated colloidal particles. The emulsion is then broken and heated at a temperature effective to cause dissociation of the weak particles while the seeds remain stable. The system is further cooled at a temperature effective that the particles stably adhere to the seed crystals resulting in growth while inhibiting nucleation of new crystals. |
| FILED | Thursday, October 19, 2023 |
| APPL NO | 18/490513 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0026 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/08 (20130101) Original (OR) Class C30B 29/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142401 | Alvarez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Noe Alvarez (Cincinnati, Ohio); Artur Huseinov (Cincinnati, Ohio); William R. Heineman (Cincinnati, Ohio) |
| ABSTRACT | Described herein are methods and devices of detecting a particulate analyte in a sample solution, using an electrochemical cell having an anodic compartment and a cathodic compartment, wherein the anodic and cathodic compartments are separated by a semi-permeable membrane. The sample solution is acidified by applying a positive current to the anodic compartment and maintaining the positive current to permit anions to flow from the cathodic compartment to the anodic compartment through the semi-permeable membrane. The analyte is deposited on an electrode disposed in the anodic compartment by applying a negative current. The deposited analyte is stripped from the electrode and an electrochemical voltammogram is generated by measuring the current as the analyte is stripped from the electrodes. The voltammogram is used to determine the concentration of the analytes in the sample solution based on the generated electrochemical voltammogram. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/496143 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/36 (20130101) G01N 27/40 (20130101) G01N 27/308 (20130101) G01N 27/413 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142405 | SIONTAS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stylianos SIONTAS (New York, New York); Jose Antonio BAHAMONDE (New York, New York); Ioannis KYMISSIS (New York, New York); Peter R. KINGET (Summit, New Jersey); Sean MC SHERRY (Jersey City, New Jersey) |
| ABSTRACT | Systems and methods for mass sensing based on integrated, functionalized piezoelectric resonators are described. A sensor includes a resonator coupled to an amplifier to form an oscillator. The resonator comprises a piezoelectric material and two or more electrodes, wherein the resonator has a first set of resonances, each with a set of electrical parameter values; a reflector underneath the resonator; a receptor coupled to the resonator, wherein the resonator has a second set of resonances, each with a set of different electrical parameter values when the target binds to the receptor; and a heating element and temperature sensor coupled to the receptor. |
| FILED | Tuesday, January 09, 2024 |
| APPL NO | 18/408545 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/022 (20130101) Original (OR) Class G01N 29/2443 (20130101) G01N 2291/014 (20130101) G01N 2291/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142686 | RUBIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Noah A. RUBIN (Cambridge, Massachusetts); Federico CAPASSO (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides an optical component, which may be a metasurface grating, including (a) a substrate; and (b) an array of subwavelength-spaced phase-shifting elements, which are tessellated on the substrate to produce, when illuminated with a polarized incident light, a diffracted light beam with a distinct polarization state for each of a finite number of diffraction orders, wherein the finite number is 2 or more. |
| FILED | Monday, December 04, 2023 |
| APPL NO | 18/528721 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) Optical Elements, Systems, or Apparatus G02B 5/3025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142705 | CHAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OAM Photonics LLC (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kam Wai Clifford CHAN (San Diego, California); Chung Ki WONG (San Diego, California) |
| ABSTRACT | The present disclosure provides an optical coherent imager implemented on a photonic integrated circuit (PIC) that enables shared path for transmitting and receiving optical signals by exploiting polarization diversity. The present disclosure also provides an optical coherent imager including an array of the optical coherent sensing units to simplify the design and calibrations of the imager, and a method for coherent sensing by the optical coherent imager. |
| FILED | Wednesday, July 21, 2021 |
| APPL NO | 17/622629 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/274 (20130101) G02B 6/2706 (20130101) G02B 6/2773 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142804 | Blumenthal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Daniel J. Blumenthal (Santa Barbara, California); Jiawei Wang (Goleta, California) |
| ABSTRACT | A Photonic molecule may include a first ring resonator that is tunable by a first piezoelectric actuator. A Photonic molecule may include a second ring resonator that is tunable by a second piezoelectric actuator, wherein the second ring resonator optically coupled to the first ring resonator. A Photonic molecule may include a third ring resonator that is tunable by a third piezoelectric actuator, wherein the third ring resonator is optically coupled to the first ring resonator and the second ring resonator. A Photonic molecule may include a waveguide optically coupled to the first ring resonator. |
| FILED | Wednesday, November 01, 2023 |
| APPL NO | 18/500008 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/29338 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0113 (20210101) Original (OR) Class G02F 2203/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142851 | LEUENBERGER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (ORLANDO, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MICHAEL N. LEUENBERGER (ORLANDO, Florida); MUHAMMAD WAQAS SHABBIR (ORLANDO, Florida) |
| ABSTRACT | A method is for operating a phased array. The method includes operating circuity coupled between first and second electrically conductive contacts to apply a voltage signal between the first and second electrically conductive contacts, change the voltage signal to selectively set phase change between IR radiation emitted from adjacent elliptical holes to emit the IR radiation at an angle from normal, and change the voltage signal to selectively set a frequency range of the IR radiation. |
| FILED | Thursday, December 07, 2023 |
| APPL NO | 18/531939 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/292 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240143689 | Jha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susmit Jha (Redwood City, California); Adam Derek Cobb (Washington, District of Columbia); Anirban Roy (San Francisco, California); Daniel Elenius (Redwood City, California); Patrick Denis Lincoln (Woodside, California) |
| ABSTRACT | In an example, a method of designing a system or architecture includes, receiving a plurality of parameter values and a set of requirements for a plurality of objective functions related to a design problem; compressing the plurality of parameters to generate a latent representation; forward processing, with one or more Invertible Neural Networks (INNs), the latent representation to generate a plurality of objective values corresponding to the plurality of the objective functions; inverse processing the plurality of objective values; and generating, based on the latent representation, a plurality of solutions to the design problem that satisfy the set of requirements for the plurality of objective functions. |
| FILED | Wednesday, October 18, 2023 |
| APPL NO | 18/489777 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/11 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240144097 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anomalee Inc. (State College, Pennsylvania) |
| ASSIGNEE(S) | Anomalee Inc. (State College, Pennsylvania) |
| INVENTOR(S) | David Jonathan Miller (State College, Pennsylvania); George Kesidis (State College, Pennsylvania); Hang Wang (State College, Pennsylvania) |
| ABSTRACT | The disclosed embodiments disclose techniques for performing universal post-training backdoor detection and mitigation for classifiers. Mitigation of overfitting for a trained classifier begins with receiving the trained classifier and a clean dataset that spans a plurality of classes for the trained classifier. A set of input patterns are used to calculate classification margins for the trained classifier, and maximum classification margins are calculated for one or more classes of the trained classifier. Overfitting can then be mitigated by reducing one or more of these calculated maximum classification margins while maintaining the accuracy of the trained classifier for the clean dataset. In some embodiments, a backdoor detector may also detect target classes for a putative backdoor in the trained classifier upon detecting that the corresponding maximum classification margins for those target classes are anomalously high compared to the maximum classification margins of other classes. |
| FILED | Thursday, October 12, 2023 |
| APPL NO | 18/485956 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240144704 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Avenue Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | c/o The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiao Wang (Cambridge, Massachusetts); Jia Liu (Cambridge, Massachusetts); Yichun He (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides methods for identifying cells in an image. An apparatus for identifying cells in an image is also provided by the present disclosure. Further provided herein is a non-transitory computer-readable storage medium for performing the methods disclosed herein. Methods of diagnosing a disease or disorder and of treating a disease or disorder in a subject using the methods disclosed are also provided herein. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 18/277950 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/44 (20220101) G06V 20/69 (20220101) Original (OR) Class G06V 2201/03 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240144998 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Deliang Fan (Tempe, Arizona); Shaahin Angizi (Newark, New Jersey) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Deliang Fan (Tempe, Arizona); Shaahin Angizi (Newark, New Jersey) |
| ABSTRACT | A system for in-memory computing comprises a volatile memory comprising at least a first layered subarray, wherein each subarray comprises a plurality of memory cells, and a plurality of sub-sense amplifiers connected to a read bitline of the first subarray of the memory, configured to compare a measured voltage of the read bitline to at least one threshold and provide at least one binary output corresponding to a logic operation based on whether the voltage of the read bitline is above or below the threshold. A method for in-memory computing is also disclosed. |
| FILED | Wednesday, November 01, 2023 |
| APPL NO | 18/499643 |
| CURRENT CPC | Static Stores G11C 11/412 (20130101) G11C 11/419 (20130101) Original (OR) Class Pulse Technique H03K 19/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145036 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Deliang Fan (Tempe, Arizona); Fan Zhang (Tempe, Arizona); Shaahin Angizi (Newark, New Jersey) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Deliang Fan (Tempe, Arizona); Fan Zhang (Tempe, Arizona); Shaahin Angizi (Newark, New Jersey) |
| ABSTRACT | A method of calculating an abundance of an mRNA sequence within a gene comprises storing an index table of the gene in a non-volatile memory, obtaining a short read of the mRNA sequence, generating a set of input fragments from the mRNA sequence, initializing a compatibility table in a volatile memory, for each input fragment in the set of input fragments, searching for an exact match of the input fragment in the index table, calculating a final result from the compatibility table, and calculating an abundance of the mRNA sequence in the gene by aggregating the transcripts compatible with the short read, wherein the calculating step is performed on the same integrated circuit as the non-volatile memory. A system for in-memory calculation of an abundance of an mRNA sequence within a gene is also disclosed. |
| FILED | Tuesday, March 21, 2023 |
| APPL NO | 18/187203 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) Original (OR) Class G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240146115 | Babakhani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Hamed Rahmani (Belle Mead, New Jersey); Hidemasa Mitsui (Santa Clara, California) |
| ABSTRACT | Systems and methods for utilizing a small form-factor, wirelessly powered transceiver are disclosed. In one embodiment, a wireless powered transceiver includes a receive antenna configured to receive a receive signal, a transmit antenna configured to transmit a transmit signal, a power harvesting system including a rectifier circuit configured convert radio frequency energy from the receive signal into DC (direct current) voltage, and a power management unit (PMU) configured to set the operating mode and biasing condition of the receive and transmit circuitry blocks and provide DC voltage from the receive circuitry block to the transmit circuitry block to maintain a minimum voltage, a receiver circuitry block configured to provide energy from the receive signal to the power harvesting system, and a transmitter circuitry block including a data modulator circuit, the data modulator circuit configured to generate the transmit signal using DC voltage received from the power management unit. |
| FILED | Wednesday, December 20, 2023 |
| APPL NO | 18/391277 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) H02J 50/27 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20240139297 | GUERRERO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | FELICITO GUERRERO (PAIGE, Texas); KYLIE G BENDELE (MASON, Texas); LUISA N DOMINGUES (ATHENS, Georgia) |
| ABSTRACT | The invention relates to antigenic polypeptides derived from a naturally occurring R. microplus protein, and nucleic acids encoding such polypeptides. The polypeptides elicit an immune response which, in turn, produces detrimental effects in R. microplus feeding on vaccinated cattle. Thus, the present disclosure provides novel vaccines to protect cattle from R. microplus infestation. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 18/052038 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0003 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/545 (20130101) A61K 2039/552 (20130101) A61K 2039/555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240140987 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Hong Liu (Corvallis, Oregon); Luguang Wang (Corvallis, Oregon); Kevin Linowski (Corvallis, Oregon) |
| ABSTRACT | Single cell protein (SCP) is produced by applying a voltage to a microbial electrolysis cell (MEC) under anaerobic conditions for a period of time, whereby SCP is produced. The MEC includes a cathode comprising a hydrogen evolution reaction material, an anode comprising a biofilm on a carbon support, an electrolyte comprising carbon, nitrogen, and phosphorus, and a Methanococcus or Acetobacterium species in the electrolyte. |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/493255 |
| CURRENT CPC | Peptides C07K 1/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141003 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fuzhong Zhang (St. Louis, Missouri); Jingyao Li (St. Louis, Missouri) |
| ABSTRACT | The present disclosure is directed to systems and methods for synthesizing a recombinant polymeric amyloid and recombinant polymeric amyloid fibers. In some embodiments, the methods comprise synthesizing tandem repeats of an amyloid peptide and a glycine-rich linker peptide in vivo in a heterologous host. In other embodiments, the recombinant polymeric amyloid fibers comprise a plurality of polymeric amyloid fibrils each comprising a plurality of β-sheet crystals, wherein the β-sheet crystals comprise tandem repeats of an amyloid peptide and a glycine-rich linker peptide, and wherein the plurality of β-sheet crystals are aligned in parallel with a fiber axis. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 18/278707 |
| CURRENT CPC | Peptides C07K 14/4711 (20130101) Original (OR) Class C07K 14/43518 (20130101) C07K 2319/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141393 | Senger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chapman University (Orange, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lilian Senger (Orange, California); Cedric Owens (Orange, California); Christine Lo Verde (Orange, California) |
| ABSTRACT | Disclosed herein are methods of reducing and/or preventing “greening” in sunflower-containing food products. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345757 |
| CURRENT CPC | Treatment, e.g Preservation, of Flour or Dough, e.g by Addition of Materials; Baking; Bakery Products; Preservation Thereof A21D 2/267 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Original (OR) Class Enzymes C12Y 301/01073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141444 | Singh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prashant Singh (Tallahassee, Florida); Joseph M. Bosilevac (Clay Center, Nebraska) |
| ABSTRACT | Disclosed herein are methods and kits for quantifying the presence of a microorganism in a sample. Specifically, disclosed are methods for quantifying a pathogen in a sample, such as a food sample, to determine if the levels of pathogen present in the sample are within an acceptable range. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 18/568614 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6851 (20130101) C12Q 2600/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141560 | Bai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xianglan Bai (Ames, Iowa); Yixin Luo (Ames, Iowa); Moham Ed Abdur Razzaq (Ames, Iowa) |
| ABSTRACT | The present application is directed to a method of producing a lignin-based carbon fiber. This method comprises providing a lignin-containing material; producing a lignin fiber from the lignin-containing material; stabilizing the lignin fiber under tension, where the tension is adjusted during said stabilizing such that the maximum bearable tension is applied to the lignin fiber; and carbonizing the lignin fiber under tension to produce a carbon fiber, where said carbonizing is carried out at a temperature below 1200° C. and where the tension during said carbonizing is adjusted to avoid shrinkage. The present application is also directed to a lignin-based carbon fiber and molded articles containing such fibers. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/495185 |
| CURRENT CPC | Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/17 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/12 (20130101) D10B 2401/10 (20130101) D10B 2401/063 (20130101) D10B 2505/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240142236 | Keshmiri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shawn Keshmiri (Lawrence, Kansas); Jeffrey Xu (Lawrence, Kansas); Aaron Mckinnis (Lawrence, Kansas) |
| ABSTRACT | A method for guiding an aerial system is described. The method includes an act of determining a plurality of reference points at a single time. The method includes one or more of an act of determining a longitudinal acceleration based on one or more of the plurality of reference points or an act of determining a lateral acceleration based on one or more of the plurality of reference points. |
| FILED | Monday, October 16, 2023 |
| APPL NO | 18/487901 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/16 (20130101) Original (OR) Class Traffic Control Systems G08G 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145066 | MUNOZ CARDONA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (WASHINGTON, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | JOHN EDISON MUNOZ CARDONA (Waterloo, Canada); CHAD L. STEPHENS (POQUOSON, Virginia); OLAFUR S. PALSSON (CHAPEL HILL, North Carolina); ALAN T. POPE (POQUOSON, Virginia) |
| ABSTRACT | Aspects relate to systems and methods for providing information about a person's physiological signals to that person (and/or others) as they travel through various venues of their daily work and play life. Ubiquitous physiological feedback incentivizes the person to regulate their cognitive and/or emotional states to better perform various tasks. The feedback also provides them with practice opportunities throughout their day to further develop a psychophysiological self-regulation skill set. Obtaining pervasive physiological feedback throughout the environment may be achieved through the person's use and/or interaction with wearable or otherwise mobile physiological monitoring devices or systems and with other systems that may be embedded in environments through which the traveler visits during the course of their day. Such systems may experience functionality changes in response to an individual's physiological signals via biocybernetic adaptation. |
| FILED | Tuesday, November 21, 2023 |
| APPL NO | 18/515868 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) Original (OR) Class G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145745 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Twelve Benefit Corporation (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sichao Ma (Dublin, California); Sara Hunegnaw (Oakland, California); Ziyang Huo (Moraga, California); Kendra P. Kuhl (Oakland, California); Etosha R. Cave (Berkeley, California); Ashley D. Mishra (Danville, California); Edward Izett (Berkeley, California); Alvin Leung (San Francisco, California); Timothy A. Bekkedahl (Fremont, California) |
| ABSTRACT | Provided herein are methods for operating carbon oxide (COx) reduction reactors (CRR) and related apparatus. In some embodiments, the methods involve shutting off, reducing, or otherwise controlling current during various operation stages including hydration, break-in, normal operation, planned shut-offs, and extended shutoff or storage periods. |
| FILED | Friday, December 15, 2023 |
| APPL NO | 18/542508 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/23 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04574 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20240141346 | PLACE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | miRecule, Inc. (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert PLACE (Gaithersburg, Maryland); Anthony SALEH (Gaithersburg, Maryland); Tishan WILLIAMS (Gaithersburg, Maryland) |
| ABSTRACT | Disclosed herein are engineered oligonucleotides for selective inhibition of polypeptide expression and activity. Also disclosed herein are methods of selectively inhibiting polypeptide expression and activity contacting an engineered oligonucleotide with a polynucleotide encoding the polypeptide. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/455756 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 47/549 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/33 (20130101) C12N 2310/141 (20130101) C12N 2310/316 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/351 (20130101) C12N 2310/531 (20130101) C12N 2310/3521 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) C12N 2320/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141349 | Stamm et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stefan Stamm (Lexington, Kentucky); Justin Ralph Welden (Lexington, Kentucky) |
| ABSTRACT | The present disclosure concerns isolated double stranded (ds) silencing RNA (siRNA) to target a backsplice junction between exons 12 and 7 in the MAPT gene. The ds siRNA include at least one nucleotide from the 3′ terminus of exon 12 linked to at least one nucleotide of the 5′ terminus of exon 7, thereby overlapping the backsplice junction. Targeting the junction ensure that that ds siRNA are limited in targeting the circular RNA produced by the backsplicing while allowing normal expression of the MAPT gene. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498834 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240142764 | NOTCUTT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STABLE LASER SYSTEMS, INC. (Boulder, Colorado) |
| ASSIGNEE(S) | STABLE LASER SYSTEMS, INC. (Boulder, Colorado) |
| INVENTOR(S) | Mark NOTCUTT (Boulder, Colorado); Josue DAVILA-RODRIGUEZ (Boulder, Colorado); William David LEE (Boulder, Colorado) |
| ABSTRACT | Methods and systems for controlling and maintaining the pressure in an ultra-stable optical resonance cavity are disclosed herein. A method for controlling and maintaining the pressure in an ultra-stable optical resonance cavity, for example, comprises providing an ultra-stable optical system housed in a vacuum housing enclosure and a pumping system in communication with the vacuum housing for maintaining a pressure in the vacuum housing less than 1×10−6 Torr. The pumping system may comprise combination pumping achieved with the simultaneous use of a getter pump and an ion pump that provide passive and active pumping, respectively. The pumping system may also comprise passive pumping only with a getter vacuum pump only. The present invention, disclosed herein, achieves passive, power-free pumping in ultra-stable laser systems thereby enhancing the portability of such systems. |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/493550 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Central Intelligence Agency (CIA)
| US 20240141308 | Borhani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ginkgo Bioworks, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Ginkgo Bioworks, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | David Borhani (Boston, Massachusetts); Dylan Alexander Carlin (Jamaica Plain, Massachusetts); Alex Tucker (Boston, Massachusetts) |
| ABSTRACT | Aspects of the disclosure relate to phosphotriesterase (PTE) enzymes and PTE-related (PTER) enzymes and their use in hydrolyzing OPNAs. |
| FILED | Friday, April 15, 2022 |
| APPL NO | 18/283688 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/08001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240146818 | Cody et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Censys, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Censys, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | Jeff Cody (Huntertown, Indiana); David Adrian (Denver, Colorado); J. Alex Halderman (Ann Arbor, Michigan); Paul A. Parkanzky (Ann Arbor, Michigan) |
| ABSTRACT | Various embodiments of apparatuses and methods for a continuous scanning engine with automatic protocol detection are described. In some embodiments, the continuous scanning engine comprises one or more discovery components and one or more protocol detection components. The discovery components, in some embodiments, send initial packets to a plurality of ports of a plurality of network addresses of a network, receive responses to a least some of the initial packets, asynchronously match the received responses to the sent initial packets, and determine that some ports at some network addresses require further analysis. The protocol inspection components, in some embodiments, attempt to communicate with the ports at the network addresses using a plurality of communication protocols, determine that an attempted communication protocols results in a successful communication, and provides the port, the network address, and the attempted communication protocol that resulted in the successful communication to a database. |
| FILED | Tuesday, January 09, 2024 |
| APPL NO | 18/408432 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/18 (20130101) H04L 67/51 (20220501) Original (OR) Class H04L 69/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20240141629 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tao Li (Mason, Ohio); Steven G. Buchberger (Montgomery, Ohio); Chandrashekhar Choudhary (Cincinnati, Ohio); Gagan Batra (San Jose, California); Toritseju Omaghomi (Cincinnati, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tao Li (Mason, Ohio); Steven G. Buchberger (Montgomery, Ohio); Chandrashekhar Choudhary (Cincinnati, Ohio); Gagan Batra (San Jose, California); Toritseju Omaghomi (Cincinnati, Ohio) |
| ABSTRACT | Systems and methods for monitoring a plumbing system. A sensor module includes an acoustic flow sensor, and is configured to be attached to a water pipe. In response to receiving sound at the acoustic flow sensor above a threshold level, the sensor module wakes up from a low-power sleep mode and begins collecting acoustic data. The acoustic data is analyzed to determine if water is flowing through the pipe, and if so, a thermal flow sensor may also be activated. Flow data is collected while the water is flowing to document the flow event. In response to the sensor module determining the flow of water has stopped, the collected data is transmitted to a remote server, and the sensor module returns to sleep mode. Multiple sensor modules can be deployed to form a sensor network that communicates wirelessly to monitor the plumbing system. |
| FILED | Thursday, October 26, 2023 |
| APPL NO | 18/495073 |
| CURRENT CPC | Installations or Methods for Obtaining, Collecting, or Distributing Water E03B 7/072 (20130101) Original (OR) Class Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/696 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240145237 | Ertsgaard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Quantinuum LLC (Broomfield, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher Todd Ertsgaard (Champlin, Minnesota); Adam Jay Ollanik (Boulder, Colorado); Todd Michael Klein (Wayzata, Minnesota); Amit Agrawal (Rockville, Maryland); Wenqi Zhu (Vienna, Virginia); Henri Joseph Lezec (Silver Spring, Maryland) |
| ABSTRACT | A method of applying a dielectric coating on a structure array of a component of an electrical device includes applying a first layer of a first dielectric material on a structure array with an atomic layer deposition (ALD) process. The structure array is formed on a substrate and has a plurality of features, each of the plurality of features having an aspect ratio of at least 1:1. |
| FILED | Tuesday, October 31, 2023 |
| APPL NO | 18/498479 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/52 (20130101) C23C 16/56 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0228 (20130101) Original (OR) Class H01L 21/02274 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20240139377 | Cullen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); Jason Brant (Wallingford, Pennsylvania); Oladayo Adewole (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided herein is a system, e.g., a living electrode, comprising a biocompatible construct comprising a matrix, and a plurality of auditory neurons. Also disclosed herein are methods of making the system, and methods of using the same for implantation in a subject, for modulating an auditory neuron in the subject, and/or for treating or alleviating a symptom of a hearing loss disorder. Further provided herein are kits comprising the system described herein. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 18/277046 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/52 (20130101) A61L 27/383 (20130101) Original (OR) Class A61L 27/3834 (20130101) A61L 27/3878 (20130101) A61L 27/3886 (20130101) A61L 2430/14 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) A61N 5/0603 (20130101) A61N 5/0622 (20130101) A61N 2005/0605 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240141687 | Dang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexis Dang (San Francisco, California); Alan Dang (San Francisco, California); Cole Cuthbert (San Francisco, California) |
| ABSTRACT | A handle extension is mountable on a handle, such as a door handle, and provides the ability to open the door by using the forearm and thus not contacting the door with the hands to mitigate fomite transmission of pathogens. The handle extension uses receiver portions which mount on the handle. A horn extends from one of the receiver portions and provides an engagement surface to accommodate the forearm. Cinching straps are used to secure the handle extension to the handle. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 18/278954 |
| CURRENT CPC | Locks; Accessories Therefor; Handcuffs E05B 1/0015 (20130101) E05B 1/0069 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20240144535 | Vemury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Arun Vemury (North Bethesda, Maryland); Yevgeniy Sirotin (Severna Park, Maryland); John Howard (Bethesda, Maryland); Jerry Tipton (Severn, Maryland) |
| ABSTRACT | Systems and methods for measuring skin tone. A camera and computer may measure skin tone health of a face dataset and color quality of a single face image. The computer and camera may measure skin tone across wide sample of volunteers, express skin tone in CIELCH coordinates; and identify the range of observed lightness, chromaticity, and hue values in the population to determine a sample set. The computer and camera may be configured to match the image to a coordinate system of lightness, chromaticity, and hue in the sample set. If a match is not possible, the computer may be configured to select a coordinate closest to the measured lightness, chromaticity, and hue. |
| FILED | Thursday, October 19, 2023 |
| APPL NO | 18/381840 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/80 (20170101) G06T 7/90 (20170101) Original (OR) Class G06T 2207/10024 (20130101) G06T 2207/30201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 20240140840 | HONG |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utal Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andy HONG (Salt Lake City, Utah) |
| ABSTRACT | An oscillating bubble reactor can include a stream inlet configured to receive a contaminated liquid stream, a reactant gas source, a serial venturi reactor (SVR), a micro-nano-bubble aerator (MNBA), and a treated stream outlet. The SVR can be connected downstream to the stream inlet and configured to receive the contaminated liquid stream. The SVR can include a set of serially connected constrictions alternating with pipe segments having a larger diameter than a smaller diameter of the constrictions. The MNBA can be in the stream inlet or the serial venturi reactor. The MNBA can be connected to the reactant gas source and configured to release reactant gas microbubbles, nanobubbles, or a combination thereof into the contaminated liquid stream from the reactant gas source. The treated stream outlet can be connected downstream to the serial venturi reactor. |
| FILED | Monday, October 30, 2023 |
| APPL NO | 18/497523 |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/231265 (20220101) B01F 23/237613 (20220101) B01F 25/3121 (20220101) B01F 25/31233 (20220101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/78 (20130101) Original (OR) Class C02F 2101/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 20240141272 | MURRAY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government, as represented by the Administrator of the U.S. EPA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jessica R. MURRAY (Durham, North Carolina); Jason Paul WEINSTEIN (Holly Springs, North Carolina); Quentin Todd KRANTZ (Chapel Hill, North Carolina); Mark HIGUCHI (Chapel Hill, North Carolina) |
| ABSTRACT | A unique aerosol-compatible cell culture exposure system is described that allow serial dilution and delivery of aerosols, reactive gases, and VOCs at air-liquid interface (ALI) under physiologically relevant conditions. Generally, the cell culture system comprise one or more dilution manifolds, one or more flow splitters, and a sealed exposure chamber that houses a commercially-available cell culture plate with corresponding transwells. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 17/977114 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/38 (20130101) C12M 23/40 (20130101) Original (OR) Class C12M 29/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20240140974 | Masson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio University (Athens, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Masson (Athens, Ohio) |
| ABSTRACT | The present disclosure concerns cucurbit[n]uril (CB) complexes of cucurbit[8]uril (CB[8]) and/or cucurbit[7]uril (CB[7]) that secure or host platinum conjugated terpyridines. The platinum center can further secure a protein through the thiol of a cysteine or an imidazole of a histidine therein. Additional CBs can secure the peptide through phenyl side chains. CB[8] will secure a dimer of platinum-terpyridines in a head-to-head alignment or a peptide dimer through a head-to-tail alignment. The application of multiple CBs allows for varying CB complex geometries. Also contemplated are methods of using the platinum-terpyridines to selectively bind cysteine rich proteins, such as cysteine proteases. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 18/554869 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6949 (20170801) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0093 (20130101) Original (OR) Class Peptides C07K 7/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/506 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, May 02, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240502.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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