FedInvent™ Patent Applications
Application Details for Thursday, July 04, 2024
This page was updated on Friday, July 19, 2024 at 04:27 PM GMT
Department of Health and Human Services (HHS)
| US 20240215818 | Tomasi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matteo Tomasi (Boston, Massachusetts); Shrinivas Pundlik (Boston, Massachusetts); Kevin Edward Houston (Norwell, Massachusetts); Gang Luo (Lexington, Massachusetts) |
| ABSTRACT | Disclosed are a mobile device and method which include acquiring, by an image acquisition unit installed in a mobile device, an image of eyes of a patient while light provided by a light source reflects from an optical surface of the eyes of the patient; and obtaining, by a processor installed in the mobile device, ocular misalignment measurements, including a magnitude and a direction of ocular misalignment in the eyes of the patient, using the acquired image or set of images. |
| FILED | Wednesday, September 13, 2023 |
| APPL NO | 18/466463 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/00 (20130101) A61B 3/08 (20130101) A61B 3/10 (20130101) A61B 3/14 (20130101) A61B 3/085 (20130101) Original (OR) Class A61B 3/152 (20130101) Image or Video Recognition or Understanding G06V 10/17 (20220101) G06V 10/141 (20220101) G06V 10/147 (20220101) G06V 40/19 (20220101) G06V 40/67 (20220101) G06V 40/193 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240215832 — A PHOTOACOUSTIC PATCH FOR THREE-DIMENSIONAL IMAGING OF HEMOGLOBIN AND CORE TEMPERATURE
| US 20240215832 | XU et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sheng XU (La Jolla, California); Xiaoxiang GAO (La Jolla, California); Hongjie HU/ (La Jolla, California); Xiangiun CHEN (La Jolla, California) |
| ABSTRACT | A wearable stretchable and/or flexible imaging device conforms to a shape of a patient surface to which it is attached. The device includes a stretchable and/or flexible encapsulation substrate and superstrate. The substrate is configured to be removably attachable to a patient surface. A stretchable and/or flexible imaging array layer is disposed between the substrate and superstrate and includes at least one ultrasound transducer for receiving ultrasound waves and at least one laser diode for generating pulses of light that cause ultrasonic emission from tissue within a patient. A stretchable and/or flexible electrical interconnect layered structure is disposed between the superstrate and substrate and is operatively coupled to the ultrasound transducer and the laser diode such that the stretchable and/or flexible electrical interconnect layered structure is configured to selectively address the at least one ultrasound transducer and the at least one laser diode. |
| FILED | Monday, May 23, 2022 |
| APPL NO | 18/288779 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0095 (20130101) Original (OR) Class A61B 5/6833 (20130101) A61B 5/14546 (20130101) A61B 2562/164 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/02 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/183 (20130101) H01S 5/04256 (20190801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240215877 | Lamberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Milo Sensors, Inc. (Santa Barbara, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Lamberg (Santa Barbara, California); Rashad Hamid (Santa Barbara, California); Bob M Lansdorp (Santa Barbara, California) |
| ABSTRACT | A device for maintaining functionality in a device reliant on active biocatalysts. A sensor has a biological catalyst, a buffered gel, and a detector component. The gelling component of the buffered gel can be adjusted to function as a barrier or semi-permeable membrane to keep the enzyme active longer. Experimental results show that the invention can sustain device activity for at least 5 days, which is normally only active for up to 1 day. |
| FILED | Thursday, December 28, 2023 |
| APPL NO | 18/398794 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1486 (20130101) Original (OR) Class A61B 5/4845 (20130101) A61B 2562/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216316 | Wiley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Buck Institute for Research on Aging (Novato, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher D. Wiley (Novato, California); Judith Campisi (Novato, California) |
| ABSTRACT | Methods are provided that relate to the discovery that dihomo-gamma linolenic acid (DGLA) is a potent senolytic agent. Accordingly, in certain embodiments, methods of selectively killing one or more senescent cells in a subject in need thereof are provided wherein the method(s) involves administering to the subject an effective amount of DGLA. |
| FILED | Tuesday, June 01, 2021 |
| APPL NO | 18/008135 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/202 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216320 | PACE et al. |
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| FUNDED BY |
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| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); Bar Ilan University (Ramat-Gan, Israel); Ramot at Tel-Aviv University Ltd. (Tel Aviv, Israel) |
| ASSIGNEE(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); Bar Ilan University (Ramat-Gan, Israel); Ramot at Tel-Aviv University Ltd. (Tel Aviv, Israel) |
| INVENTOR(S) | Betty S. PACE (Augusta, Georgia); Abraham NUDELMAN (Rehovot, Israel); Zvi MALIK (Kfar Haroeh, Israel); Ada REPHAELI (Tel Aviv, Israel) |
| ABSTRACT | It has been found that the prodrug 1-(butyryloxy)ethyl-5-amino-4-oxopentanoate (AN-233), an oral active conjugate of BA (histone deacetylase inhibitor) and ALA (heme precursor), is useful for the treatment of hemoglobinopathies including but not limited to sickle cell disease and thalassemias. In one embodiment, AN-233 activates γ-globin transcription, induces HbF expression, produces an anti-sickling effect, or combinations thereof when administered to a subject in need thereof. |
| FILED | Thursday, March 14, 2024 |
| APPL NO | 18/605474 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0053 (20130101) A61K 31/17 (20130101) A61K 31/22 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216325 | BUTCHER et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan BUTCHER (Ithaca, New York); Abulajiang MAIHEMUTI (Ithaca, New York); Terrence GEE (Laguna Niguel, California) |
| ABSTRACT | The present application relates to a method for inhibiting calcification of aortic valves or inhibiting aortic valve sclerosis/fibrosis. The method involves selecting a subject having, or at risk of developing, calcific aortic valve disease or aortic valve sclerosis/fibrosis and administering, to the selected subject, an inhibitor of the nuclear factor kappa B (NFKB) signaling pathway to inhibit calcification of the selected subject's aortic valves or aortic valve sclerosis/fibrosis. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/779472 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/277 (20130101) Original (OR) Class A61K 31/381 (20130101) A61K 31/519 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216336 | Ardehali et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hossein Ardehali (Chicago, Illinois); Adam De Jesus (Chicago, Illinois) |
| ABSTRACT | Disclosed are methods for the treatment of immunodeficiency diseases or disorders in subjects in need thereof by administering to the subject an effective amount of a therapeutic agent that results in dissociation of hexokinase 1 (HK1) from the outer membrane of mitochondria and into the cytosol of macrophage cells in the subject and results in inducing a hyperinflammatory response in the subject. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 18/006688 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/335 (20130101) A61K 31/365 (20130101) A61K 31/4174 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216343 | Sonkusare |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Swapnil Sonkusare (Charlottesville, Virginia) |
| ABSTRACT | Disclosed are methods for treating pulmonary hypertension by activating the endothelial intermediate potassium (IK) and endothelial small potassium (SK) channels in a subject in need thereof. |
| FILED | Wednesday, January 03, 2024 |
| APPL NO | 18/403572 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/426 (20130101) Original (OR) Class A61K 31/4184 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216346 | Hu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Wistar Institute (Philadelphia, Pennsylvania); University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chih-Chi Andrew Hu (Philadelphia, Pennsylvania); Juan R. Del Valle (Tampa, Florida) |
| ABSTRACT | The present invention includes substituted chromenones that are useful to inhibit the IRE1/XBP-1 pathway. In certain embodiments, the compounds of the invention inhibit IRE1's RNase activity. In other embodiments, the compounds of the invention are useful to treat or prevent a cancer that involve activation of the ER stress response. The invention also relates, in certain aspects, to the discovery that secretory IgM (sIgM) can orchestrate an immunosuppressive microenvironment by recruiting myeloid-derived suppressor cells (MDSCs) into different tumor models, such as but not limited to solid tumors (such as lung cancer) and tumors that have high levels of secreted IgM. In certain embodiments, sIgM produced by B cells or CLL cells can contribute to the accumulation of MDSCs in a tumor. In other embodiments, inhibition of the IRE1/XBP-1 pathway can ablate, minimize, or reduce MDSC levels in a tumor. |
| FILED | Thursday, October 05, 2023 |
| APPL NO | 18/376983 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 491/052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216354 | Hideshima et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Teru Hideshima (Brookline, Massachusetts); Kenneth C. Anderson (Wellesley, Massachusetts) |
| ABSTRACT | The present disclosure provides methods of treating a disease in a subject in need thereof (e.g., proliferative diseases (e.g., cancer (e.g., multiple myeloma))) comprising administering to a subject in need thereof an effective amount of an immunomodulatory drug (e.g., pomalidomide, thalidomide, lenalidomide, iberdomide). The disclosed IMiDs may increase the activity of a kinase (e.g., Zap-70). Also provided are kits comprising the disclosed IMiDs. |
| FILED | Thursday, October 01, 2020 |
| APPL NO | 17/766189 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) A61K 31/454 (20130101) Original (OR) Class A61K 31/573 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216365 | Anathy et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| ASSIGNEE(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
| INVENTOR(S) | Vikas Anathy (Essex Junction, Vermont); Nicolas Chamberlain (Burlington, Vermont); Amit Kumar (Burlington, Vermont) |
| ABSTRACT | Compositions and methods involving protein disulfide isomerase (PDI) inhibitors, such as protein disulfide isomerase A3 (PDIA3) inhibitory compounds, for human coronavirus, such as severe acute respiratory syndrome (SARS) virus (e.g., SARS-CoV-2), therapies are disclosed herein. |
| FILED | Friday, December 15, 2023 |
| APPL NO | 18/542451 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/381 (20130101) A61K 31/427 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/675 (20130101) A61K 31/4965 (20130101) A61K 31/7048 (20130101) A61K 31/7068 (20130101) A61K 35/16 (20130101) A61K 39/42 (20130101) A61K 39/3955 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216372 | GUNJAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Akash GUNJAN (Tallahassee, Florida); Yuna SON (Waltham, Massachusetts) |
| ABSTRACT | This disclosure relates to pharmaceutical compositions comprising one or more therapeutic agents selected from a SERPINE1 serine protease inhibitor, a histone acetyltransferase inhibitor, a histone deacetylase inhibitor, an insulin-like growth factor inhibitor, an anti-hypertensive agent, a topoisomerase II inhibitor, a tyrosine kinase inhibitor, an agent that downregulates growth factors or any combination thereof, and methods of treating fibrotic disorders, including keloid, pulmonary fibrosis, hepatic fibrosis, cardiac fibrosis, renal fibrosis, mediastinal fibrosis, retroperitoneal cavity fibrosis, bone marrow fibrosis, and/or scleroderma using the same. The disclosed methods can be accompanied by application of radiation and/or surgical resection. For treating keloids, the compositions can be formulated topically and do not cause systemic side effects. For treating fibrotic diseases of internal organs, the compositions can be administered systemically or delivered to the affected organs. The compositions can include two or more therapeutic agents that work synergistically, allowing lower doses of each therapeutic agent. |
| FILED | Thursday, December 28, 2023 |
| APPL NO | 18/398315 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/136 (20130101) A61K 31/167 (20130101) A61K 31/405 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/4418 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216376 | Wood et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kris Wood (Durham, North Carolina); Kevin Lin (Durham, North Carolina); Justine Rutter (Durham, North Carolina) |
| ABSTRACT | Described herein is a combination therapy for the treatment of a cancer in a subject. In one aspect, the therapy comprises selinexor and one or more second anti-cancer agents. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 18/558211 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/497 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216391 | SMITH et al. |
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| FUNDED BY |
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| APPLICANT(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | Jill P. SMITH (Camp Hill, Pennsylvania); Louis WEINER (Washington, District of Columbia); Sandra JABLONSKI (Silver Spring, Maryland); Sandeep NADELLA (Alexandria, Virginia); Shangzi WANG (Derwood, Maryland) |
| ABSTRACT | Provided herein are methods for treating fibrosis (e.g. pancreatic fibrosis) in a subject. Some methods comprise administering to a subject having pancreatic fibrosis an effective amount of a CCK receptor inhibitor. |
| FILED | Friday, February 09, 2024 |
| APPL NO | 18/437859 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) A61K 31/5513 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216410 | JENQ et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Robert R. JENQ (Houston, Texas); Mohamed A. JAMAL (Houston, Texas); Jennifer L. KARMOUCH (Houston, Texas); Eiko HAYASE (Houston, Texas) |
| ABSTRACT | The current disclosure provides methods and compositions related to treating or preventing neutropenic fever (e.g., cancer therapy-induced neutropenic fever) and/or GVHD (e.g., HCT-related and/or neutropenic fever therapy-induced GVHD). In specific cases, it may be determined whether or not the subject is likely to develop or is at risk of developing neutropenic fever and/or GVHD, such as cancer therapy-induced neutropenic fever and/or HCT-related and/or neutropenic fever therapy-induced GVHD, based on the subject's gut microbiome. A subject may be provided a composition comprising one or more agents targeting growth or expansion the one or more genera of mucus-degrading gut bacteria, one or more mucus-degrading enzyme inhibitors, one or more mediators of organic acid metabolite levels, and/or one or more carbohydrate substrates metabolized by the one or more genera of mucus-degrading gut bacteria based on analysis of the gut microbiome of the subject receiving a HCT therapy and/or a neutropenic fever therapy following administration of a cancer therapy, in specific embodiments. |
| FILED | Thursday, March 24, 2022 |
| APPL NO | 18/283408 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/12 (20130101) A61K 31/19 (20130101) A61K 31/407 (20130101) A61K 31/546 (20130101) A61K 31/714 (20130101) A61K 31/4045 (20130101) A61K 31/7004 (20130101) A61K 31/7052 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216412 | TIAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | RONG TIAN (Seattle, Washington); MATTHEW WALKER (Seattle, Washington) |
| ABSTRACT | The current disclosure provides provides boosting intracellular NAD+ with nicotinamide riboside chloride (NR) to protect from cardiac dysfunction, NR being a natural NAD+ precursor that bypasses nicotinamide phosphoribosyltransferase (NAMPT) to stimulate intracellular NAD+ synthesis. |
| FILED | Wednesday, November 22, 2023 |
| APPL NO | 18/517421 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/706 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216414 | Schinazi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raymond F. Schinazi (Atlanta, Georgia); Franck Amblard (Atlanta, Georgia); Bryan D. Cox (Suwanee, Georgia); Leda Bassit (Smyrna, Georgia); Longhu Zhou (Atlanta, Georgia); Christina Gavegnano (Atlanta, Georgia) |
| ABSTRACT | The present invention is directed to compounds, compositions and methods for treating or preventing Zika virus. The compounds include pyrimidine and purine nucleosides and prodrugs thereof, including certain N4-hydroxycytidine nucleoside derivatives, sulfasalazine, and various entry inhibitors. |
| FILED | Tuesday, March 12, 2024 |
| APPL NO | 18/603143 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) A61K 31/655 (20130101) A61K 31/4706 (20130101) A61K 31/7064 (20130101) A61K 31/7068 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216425 | Discher et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dennis E. Discher (Philadelphia, Pennsylvania); Jason Christopher Andrechak (Philadelphia, Pennsylvania); Lawrence Dooling (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods that provide modified phagocytes (e.g., macrophages) or precursor cells thereof useful for the treatment of cancer in subjects in need thereof. |
| FILED | Friday, December 29, 2023 |
| APPL NO | 18/400822 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Original (OR) Class A61K 39/4614 (20230501) A61K 39/464402 (20230501) A61K 39/464456 (20230501) A61K 2239/13 (20230501) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/705 (20130101) C07K 16/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0645 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 2310/20 (20170501) C12N 2740/15043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216466 | KAPILOFF et al. |
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| FUNDED BY |
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| APPLICANT(S) | Anchored RSK3 Inhibitors, LLC (Los Altos, California) |
| ASSIGNEE(S) | Anchored RSK3 Inhibitors, LLC (Los Altos, California) |
| INVENTOR(S) | Michael S. KAPILOFF (Los Altos, California); Jinliang LI (Palo Alto, California); Michael KRITZER (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAPβ, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAPβ binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3. |
| FILED | Monday, February 05, 2024 |
| APPL NO | 18/432983 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/713 (20130101) A61K 31/7048 (20130101) A61K 38/005 (20130101) A61K 38/45 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 48/00 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 207/11001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216468 | MANTUANO et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Elisabetta MANTUANO (La Jolla, California); Steven L GONIAS (La Jolla, California) |
| ABSTRACT | The present disclosure provides novel anti-inflammatory therapeutics, and method of use thereof. The disclosed anti-inflammatory therapeutics comprise soluble, membrane-anchored, and/or extracellular vesicle (EV)-associated PrPC, and/or analogues thereof, that interacts with NMDA-R/LRP1 receptor complext to regulate innate immunity and provide anti-inflammatory activity in diseases in which innate immunity plays an important role. |
| FILED | Monday, April 18, 2022 |
| APPL NO | 18/554705 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) Original (OR) Class A61K 47/6901 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216502 | MASON et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hugh MASON (Phoenix, Arizona); Andrew DIAMOS (Tempe, Arizona); Mary PARDHE (Phoenix, Arizona); Brandon FAVRE (Los Gatos, California) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Hugh MASON (Phoenix, Arizona); Andrew DIAMOS (Tempe, Arizona); Mary PARDHE (Phoenix, Arizona); Brandon FAVRE (Los Gatos, California) |
| ABSTRACT | The disclosure relates to vaccination compositions, for example, against human papillomavirus, Zika virus, and flu virus. The disclosure also relates to vectors for producing the virus-like particles and immune complex platforms of the vaccination compositions. |
| FILED | Wednesday, November 08, 2023 |
| APPL NO | 18/504962 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 39/292 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/505 (20130101) A61K 2039/575 (20130101) A61K 2039/5258 (20130101) A61K 2039/6056 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/20023 (20130101) C12N 2710/20034 (20130101) C12N 2710/20071 (20130101) C12N 2730/10123 (20130101) C12N 2730/10134 (20130101) C12N 2730/10171 (20130101) C12N 2760/16123 (20130101) C12N 2760/16134 (20130101) C12N 2760/16171 (20130101) C12N 2770/24134 (20130101) C12N 2770/24171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216507 | BOLLARD et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CHILDREN'S NATIONAL MEDICAL CENTER (Washington, District of Columbia) |
| ASSIGNEE(S) | CHILDREN'S NATIONAL MEDICAL CENTER (Washington, District of Columbia) |
| INVENTOR(S) | Catherine BOLLARD (Washington, District of Columbia); Michael KELLER (Washington, District of Columbia); Chris LAZARSKI (Washington, District of Columbia); Allistair ABRAHAM (Washington, District of Columbia); Patrick HANLEY (Washington, District of Columbia); Conrad Russell Y. CRUZ (Washington, District of Columbia) |
| ABSTRACT | The invention pertains to a method for preventing or treating SARS-CoV-2 infection by administering SARS-CoV-2 specific T cells which recognize particular peptide epitopes in SARS-CoV-2 spike (S), nucleocapsid (N), membrane, and envelope proteins. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/907180 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) Original (OR) Class A61K 39/464838 (20230501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2501/2304 (20130101) C12N 2501/2307 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216523 | Parhiz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hamideh Parhiz (Gladwyne, Pennsylvania); Drew Weissman (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for effective delivery of an agent to a stem cell using a delivery vehicle comprising a stem cell targeting domain. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 18/558015 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6807 (20170801) A61K 47/6849 (20170801) Original (OR) Class A61K 47/6925 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216527 | de los Pinos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aura Biosciences, Inc. (Boston, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Serv. (Bethesda, Maryland) |
| ASSIGNEE(S) | Aura Biosciences, Inc. (Boston, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Serv. (Bethesda, Maryland) |
| INVENTOR(S) | Elisabet de los Pinos (Brookline, Massachusetts); John Todd Schiller (Kensington, Maryland); Rhonda C. Kines (Washington, District of Columbia); John MacDougall (Hingham, Massachusetts) |
| ABSTRACT | The present disclosure is directed to methods and compositions for the diagnosis and/or treatment of tumors, such as ocular tumors, using virus-like particles conjugated to photosensitive molecules. |
| FILED | Thursday, March 14, 2024 |
| APPL NO | 18/605198 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 41/0057 (20130101) A61K 41/0071 (20130101) A61K 47/64 (20170801) A61K 47/6901 (20170801) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/585 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Peptides C07K 1/13 (20130101) C07K 14/025 (20130101) C07K 16/32 (20130101) C07K 16/084 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/20023 (20130101) C12N 2710/20033 (20130101) C12N 2710/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216530 | Quijano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut); Gennao Bio, Inc. (Pennington, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elias Quijano (New Haven, Connecticut); Peter Glazer (New Haven, Connecticut); Bruce C. Turner (Bryn Mawr, Pennsylvania); Stephen Squinto (New York, New York) |
| ABSTRACT | Compositions and methods are provided for treating myopathies by administering a complex formed between a therapeutic mRNA polynucleotide and a 3E10 antibody or variant thereof, or antigen-binding fragment thereof. In some instances, the complexes are stabilized through a molar ratio of 3E10 antibody or variant thereof, or antigen-binding fragment thereof to therapeutic polynucleotide of at least about 2:1. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 18/548823 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1719 (20130101) A61K 47/6807 (20170801) A61K 48/0025 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Peptides C07K 16/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216541 | Sheikh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Farah Sheikh (San Diego, California); William Bradford (Solana Beach, California) |
| ABSTRACT | Compositions and methods for preventing and treating cardiac arrhythmia. Methods of preventing or treating arrhythmogenic right ventricular cardiomyopathy (ARVC), comprising administering to a subject in need a prophylactic or treatment effective amount of a composition comprising a plakophilin-2 (PKP2) gene. The composition further comprises an adenovirus-associated vector (AAV) to deliver the PKP-2 gene. In embodiments, the invention provides that the AAV is a cardiotropic AAV serotype and contains a cardiac-specific promoter. Method of treating a cardiovascular disease characterized by abnormal cardiac cell-cell junction complex comprising administering to a subject in need a prophylactic or treatment effective amount of a composition comprising a plakophilin-2 (PKP2) gene. |
| FILED | Tuesday, April 12, 2022 |
| APPL NO | 18/554771 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/1709 (20130101) A61K 48/0058 (20130101) Original (OR) Class A61K 48/0075 (20130101) A61K 48/0083 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216553 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yongjian Liu (St. Louis, Missouri); Xiuli Zhang (St. Louis, Missouri); Gyu Seong Heo (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of compositions of CD163 targeting and theranostic agents and methods for use in detecting, monitoring, and evaluating CD163 associated diseases, disorders, and conditions. |
| FILED | Friday, December 29, 2023 |
| APPL NO | 18/400969 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/088 (20130101) Original (OR) Class A61K 51/0482 (20130101) A61K 2121/00 (20130101) A61K 2123/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216571 | Clare et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tricol Biomedical, Inc. (Portland, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian Clare (Portland, Oregon); Radim Dvorák (Popuvky, Czech Republic); Simon McCarthy (Portland, Oregon); Jirí Machát (Brno, Czech Republic) |
| ABSTRACT | The present chitosan-based superfine fiber invention relates to compositions, formulations, and processes that result in numerous significant advantages for the production and use of superfine fiber bioactive matrices in biomedical applications. The present invention relates to superfine, chitosan-based fibers, wherein the chitosan-based fibers have a percentage chitosan content of at least about 20% w/w, and highly conformable and compliant matrices comprising such fibers, processes for their production, and related formulations. The superfine chitosan-based fibers of the invention preferably include microfibers with diameter less than or equal to about 10 microns and micron and submicron fibers that are about 2 microns and less. |
| FILED | Wednesday, January 17, 2024 |
| APPL NO | 18/415412 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/28 (20130101) Original (OR) Class A61L 15/425 (20130101) A61L 24/08 (20130101) A61L 24/0036 (20130101) A61L 27/20 (20130101) A61L 27/50 (20130101) A61L 27/56 (20130101) A61L 2400/04 (20130101) A61L 2430/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/02 (20130101) D01D 5/08 (20130101) D01D 5/18 (20130101) D01D 5/084 (20130101) D01D 10/02 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/02 (20130101) D01F 9/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216584 | Slepian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of The University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marvin Slepian (Tucson, Arizona); Daniel Palomares (Tucson, Arizona); Kaitlyn Ammann (Tucson, Arizona); Syed Hossainy (Tucson, Arizona) |
| ABSTRACT | Systems, devices, and methods for generating fiber constructs via electrospinning are disclosed herein. The system for generating fiber constructs includes an ejection device and a collector. The collector contains a collection surface with patterns formed by conductive trace(s). The conductive trace(s) is arranged such that the resulting electric field lines are either undisturbed electrostatic field lines or blurred electrostatic field lines aligned around each conductive trace. Methods of generating fiber constructs using the system via electrospinning includes applying an electrostatic charge to the ejection device or a component thereof. The formed fiber construct has a grammage that is at least 5% higher than a grammage of a fiber construct formed on an un-patterned collector under the same conditions. The electrospun fiber constructs may be used for forming engineered tissues or implants, wound dressings, drug delivery formulations, and implant or device coatings. |
| FILED | Thursday, March 10, 2022 |
| APPL NO | 18/549770 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/54 (20130101) Original (OR) Class A61L 27/56 (20130101) A61L 27/3826 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0038 (20130101) D01D 5/0076 (20130101) D01D 5/0092 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/56 (20130101) D04H 1/435 (20130101) D04H 1/728 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/041 (20130101) D10B 2509/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216628 | Driehuys et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bastiaan Driehuys (Chapel Hill, North Carolina); Alexander Church (Durham, North Carolina) |
| ABSTRACT | Devices that allow serially controlled delivery of room air for practice inhalation and breath-hold procedures and a different (image contrast) gas for inhalation for a medical procedure include an actuator that is controllably, pneumatically operated by a user via a length of conduit. |
| FILED | Thursday, April 21, 2022 |
| APPL NO | 18/558203 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0078 (20130101) Original (OR) Class A61M 16/201 (20140204) A61M 16/0816 (20130101) A61M 16/0833 (20140204) A61M 2205/073 (20130101) A61M 2205/075 (20130101) A61M 2205/8218 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216662 | Gage et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | InnAVasc Medical, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shawn M. Gage (Raleigh, North Carolina); Joseph Knight (Durham, North Carolina); Michael Lawson (Durham, North Carolina); Craig Nichols (Carrboro, North Carolina) |
| ABSTRACT | An apparatus is provided for rotatable selection of sites for cannulation with a needle along a subcutaneous vascular access vessel. The cannulation site selection apparatus comprises a template having an inner surface and an outer surface, and a plurality of visible markings on the outer surface of the template. The template is adapted to be disposed adjacent the subcutaneous vascular access vessel such that the markings align with the cannulation sites along the vascular access vessel for selecting a site for cannulation with a needle into the vascular access vessel. |
| FILED | Wednesday, January 31, 2024 |
| APPL NO | 18/428903 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/30 (20130101) A61M 1/3655 (20130101) A61M 1/3661 (20140204) A61M 5/427 (20130101) A61M 39/0208 (20130101) Original (OR) Class A61M 2039/0238 (20130101) A61M 2205/583 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216761 | Knarr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Brian Knarr (Omaha, Nebraska); Travis Vanderheyden (Omaha, Nebraska); Russell Buffum (Omaha, Nebraska) |
| ABSTRACT | A system for controlling exercise equipment based on user pace and motion analysis is disclosed. The system includes a control unit communicatively coupled with a center of mass (COM) sensor and one or more additional sensors. The COM sensor is configured to track a position of a body of a user on the exercise equipment over time. The one or more additional sensors are configured to track off-center movements of the user over time. The control unit is configured to modulate an adjustable parameter of the exercise equipment based on a plurality of measurements of the user's body position and off-center movements collected by the COM sensor and the one or more additional sensors over time. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 18/563817 |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 22/025 (20151001) A63B 24/0021 (20130101) A63B 24/0087 (20130101) Original (OR) Class A63B 2024/0025 (20130101) A63B 2024/0093 (20130101) A63B 2220/10 (20130101) A63B 2220/30 (20130101) A63B 2220/805 (20130101) A63B 2220/833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216900 | Swenson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Rolf E. Swenson (Silver Spring, Maryland); Jessica H. Ettedgui-Benjamini (North Bethesda, Maryland); Carolyn Woodroofe Hitko (Olney, Maryland); Murali K. Cherukuri (Potomac, Maryland); Natarajan Raju (Germantown, Maryland) |
| ABSTRACT | Disclosed are perfluorinated SABRE catalysts comprising a d-block element and a perfluorinated ligand, wherein the perfluorinated ligand is of Formula (I): [Lm-(NHC)—(Y—Z)q] or a salt thereof. Also disclosed is a method of preparing a hyperpolarized substrate comprising a ½ spin nucleus or nuclei using the perfluorinated SABRE catalysts, and isolating the resulting hyperpolarized substrate for administration to an animal. Further disclosed is a method of imaging a tissue of an animal suspected of having a disease or condition. |
| FILED | Thursday, January 11, 2024 |
| APPL NO | 18/410773 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/226 (20130101) B01J 31/2273 (20130101) B01J 31/2295 (20130101) Original (OR) Class B01J 2231/005 (20130101) B01J 2531/004 (20130101) B01J 2531/827 (20130101) Acyclic or Carbocyclic Compounds C07C 51/487 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216911 | Schenk zu Schweinsberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ABBOTT DIAGNOSTICS SCARBOROUGH, INC. (SCARBOROUGH, Maine) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Schenk zu Schweinsberg (Jena, Germany); Austin Matthew Derfus (Solana Beach, California); Justin Davidson (San Diego, California); Karthikeyan Kumaravadivelu (San Diego, California); Maulik Vinod Patel (La Crescenta, California); Olaf Piepenburg (Saffron Walden, United Kingdom); Catherine Jean Greenwood (Sawbridgeworth, United Kingdom); Oliver Nentwich (Cambridge, United Kingdom) |
| ABSTRACT | A microfluidic device includes an inlet port configured to receive a sample, a first reaction chamber fluidically coupled to the inlet port, a first pump fluidically coupled to the inlet port, a second pump fluidically coupled to a mixing chamber, a metering channel fluidically coupled to the first reaction chamber and to the mixing chamber, and one or more second reaction chambers fluidically coupled to the mixing chamber. The first pump is configured to move fluid from the inlet port to the first reaction chamber and from the first pump to the inlet port. The second pump is configured to move fluid from the second pump to the mixing chamber, from the first reaction chamber to the mixing chamber, and from the mixing chamber to the one or more second reaction chambers. |
| FILED | Wednesday, January 10, 2024 |
| APPL NO | 18/409552 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5029 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 2200/027 (20130101) B01L 2200/082 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/0478 (20130101) B01L 2400/0655 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/14 (20130101) G01N 1/38 (20130101) G01N 35/00069 (20130101) G01N 2001/028 (20130101) G01N 2035/00158 (20130101) G01N 2035/1034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216914 | Ros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alexandra Ros (Phoenix, Arizona); Daihyun Kim (Mesa, Arizona); Jinghui Luo (Covina, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandra Ros (Phoenix, Arizona); Daihyun Kim (Mesa, Arizona); Jinghui Luo (Covina, California) |
| ABSTRACT | Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel. |
| FILED | Tuesday, March 12, 2024 |
| APPL NO | 18/603030 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2400/086 (20130101) B01L 2400/0406 (20130101) B01L 2400/0415 (20130101) B01L 2400/0424 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 5/028 (20130101) B03C 2201/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2001/4038 (20130101) G01N 2015/0038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217180 | McLeod et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (DENVER, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert R. McLeod (Boulder, Colorado); Charles M. Rackson (, None) |
| ABSTRACT | Systems and methods for improved volumetric additive manufacturing (VAM) are described herein. In some aspects of the present disclosure, approaches to VAM image-computation are provided that algebraically optimizes directly on the structure to be printed, instead of on the set of external projection images. These approaches provide multiple advantages including improved reconstruction fidelity, simplicity, flexibility, and robust convergence to a desirable reconstruction, regardless of initial image-set guess. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 18/288713 |
| CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 7/08 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) B29C 64/241 (20170801) B29C 64/393 (20170801) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217979 | Liotta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dennis C. Liotta (Atlanta, Georgia); Stephen F. Traynelis (Decatur, Georgia); David S. Menaldino (Atlanta, Georgia); Peipei Ma (Atlanta, Georgia) |
| ABSTRACT | Compounds that selectively inhibit the GluN2 subunits of NMDA receptors are disclosed. In general, the compounds have superior activity against GluN2C/D subunit(s) over GluN2A/B subunit(s). Optionally, the compounds have a structure of Formulas (I), (II), (III), or other formulas disclosed herein, enantiomers or diastereomers thereof, or pharmaceutically acceptable salts thereof. Pharmaceutical formulations containing one or more of the compounds are also disclosed. Additionally, methods of treating a neurological condition or disorder using the compounds or their pharmaceutical formulations thereof are disclosed. Exemplary neurological conditions or disorders include Parkinson's disease, dystonia and related motor disorders, depression, neuropsychiatric indications, stoke, hypoxia, traumatic brain injury, acute injuries involving the white matter, Alzheimer's disease, compulsivity and related disorders, and epilepsy. |
| FILED | Thursday, April 21, 2022 |
| APPL NO | 18/287844 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) A61K 31/437 (20130101) A61K 31/519 (20130101) A61K 31/4365 (20130101) A61K 31/4375 (20130101) A61K 31/4439 (20130101) A61K 31/4709 (20130101) A61K 31/5025 (20130101) Heterocyclic Compounds C07D 231/06 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) C07D 487/04 (20130101) Original (OR) Class C07D 495/04 (20130101) C07D 513/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217997 | DOWD et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GEORGE WASHINGTON UNIVERSITY (NW Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cynthia S. DOWD (NW Washington, District of Columbia); Darean BAGUE (Arlington, Virginia); Ruiqin WANG (Annandale, Virginia); Audrey R. Odom JOHN (Philadelphia, Pennsylvania); Robin D. COUCH (Manassas, Virginia); Helena I. BOSHOFF (Potomac, Maryland) |
| ABSTRACT | The present disclosure relates to novel compounds useful as antimicrobial agents. The present disclosure also relates to processes for their preparation, pharmaceutical compositions comprising them, and to their use in methods for treating or preventing microbial infections caused by parasites or bacteria, such as, for example, Plasmodium falciparum or related Plasmodium parasite species, Mycobacterium tuberculosis or related Mycobacterium bacteria species, S. aureus, and ESKAPE pathogens. |
| FILED | Friday, April 15, 2022 |
| APPL NO | 18/555194 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/662 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/4056 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218017 | JUN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UAB RESEARCH FOUNDATION (Birmingham, Alabama); Endomimetics LLC (BIRMINGHAM, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | HO-WOOK JUN (Birmingham, Alabama); BRIGITTA BROTT (Birmingham, Alabama); XIXI ZHANG (Birmingham, Alabama); JUN CHEN (Birmingham, Alabama); BENJAMIN K. ESTEP (Birmingham, Alabama); JENNIFER SHERWOOD (Birmingham, Alabama); PATRICK HWANG (Birmingham, Alabama) |
| ABSTRACT | Disclosed are peptide amphiphiles comprising a hydrophilic peptide sequence and a hydrophobic tail, wherein the hydrophobic tail comprises a moiety having a substituted C16 alkyl chain, wherein the hydrophilic peptide sequence comprises a degrading sequence (DS), wherein the degrading sequence (DS) comprises the amino acid sequence GTAGLIGQ (SEQ ID NO:1) wherein the DS comprises one or more amino acid substitutions. Also disclosed are compositions, liposomes, gels, and medical devices comprising the peptide amphiphiles and methods of use thereof. |
| FILED | Friday, October 06, 2023 |
| APPL NO | 18/482745 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218018 | Lambris |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | John D. Lambris (Philadelphia, Pennsylvania) |
| ABSTRACT | Compounds comprising peptides capable of binding C3 protein and inhibiting complement activation are disclosed. The compounds comprise compstatin analogs in which the N-terminus and/or C-terminus contains an added component that improves (1) the peptide's solubility at physiological pH; (2) the peptide's plasma half-life; (3) the peptide's intraocular retention; and/or (4) the peptide's binding affinity to C3 or its fragments as compared to an unmodified compstatin peptide under equivalent conditions. Pharmaceutical compositions and methods of using the compounds are also disclosed. |
| FILED | Monday, January 29, 2024 |
| APPL NO | 18/426136 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 38/00 (20130101) A61K 47/60 (20170801) Peptides C07K 7/08 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218027 | ROMESBERG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Floyd E. ROMESBERG (La Jolla, California); Yorke ZHANG (San Diego, California) |
| ABSTRACT | Disclosed herein are proteins, methods, cells, engineered microorganisms, and kits for generating a modified nucleoside triphosphate transporter from Phaeodactylum tricornutum. Also disclosed herein proteins, methods, cells, engineered microorganisms, and kits for production of a nucleic acid molecule that comprises an unnatural nucleotide utilizing a modified nucleoside triphosphate transporter from Phaeodactylum tricornutum. |
| FILED | Tuesday, November 07, 2023 |
| APPL NO | 18/503341 |
| CURRENT CPC | Peptides C07K 14/405 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/10 (20130101) C12N 15/11 (20130101) C12N 15/90 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218041 | WEISS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael A. WEISS (Indianapolis, Indiana); Mark A. JAROSINSKI (Fishers, Indiana) |
| ABSTRACT | A two-chain insulin analogue is provided containing (a) a B chain modified by the addition of a C-terminal diol element in combination with (b) a glucose-binding element attached to the A chain at or near its N terminus, optionally linked to a D-amino acid. A “flipped” set of insulin analogues wherein the A chain is modified by addition of an N-terminal diol element whereas the glucose-binding element is attached at or near the C terminus of the B chain is also provided. Compositions comprising such insulin analogues are used in methods of treating a patient with diabetes mellitus. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 18/288925 |
| CURRENT CPC | Peptides C07K 1/1077 (20130101) C07K 14/622 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218052 | MCGREGOR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | APPLIED BIOMEDICAL SCIENCE INSTITUTE (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Duncan MCGREGOR (San Diego, California); Ruiqi HUANG (San Diego, California); Gabrielle WARNER JENKINS (San Diego, California); Vaughn SMIDER (San Diego, California) |
| ABSTRACT | The present disclosure relates to methods of producing and screening display libraries of disulfide-bonded binding polypeptides, for instance to identify binding peptides specific for a target molecule. In some embodiments, the binding peptides comprise an ultralong CDR3. The binding peptides can be derived from a bovine antibody comprising an ultralong CDR3, or they can be synthetic or semisynthetic. Also provided herein are display libraries comprising disulfide-bonded binding polypeptides. The present disclosure also relates to methods of producing or expressing soluble disulfide-bonded binding polypeptides, for instance using a suitable host cell. Also provided herein are compositions comprising soluble disulfide-bonded binding polypeptides. |
| FILED | Wednesday, May 11, 2022 |
| APPL NO | 18/285827 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/005 (20130101) Original (OR) Class C07K 16/1003 (20230801) C07K 2317/24 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) C12N 15/70 (20130101) C12N 15/1096 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/19 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218055 | Ho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Mitchell Ho (Urbana, Maryland); Peter D. Kwong (Washington, District of Columbia); Zhijian Duan (Columbia, Maryland); Yaping Sun (New Haven, Connecticut); Sao-Fong Cheung (Rockville, Maryland); Jason J. Gorman (Lakeville, Massachusetts) |
| ABSTRACT | Single-domain monoclonal antibodies that specifically bind Lassa virus glycoprotein (GPC) are described. The single-domain antibodies (“nanobodies”) were isolated from camel (VHH) and shark variable new antigen (VNAR) phage display libraries panned against a stabilized form of the GPC trimer. The GPC-specific nanobodies, and conjugates thereof, can be used for the diagnosis and treatment of a Lassa virus infection. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 18/557741 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6841 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/543 (20130101) G01N 33/56983 (20130101) G01N 2333/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218057 | Nussenzweig |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michel C. Nussenzweig (New York, New York) |
| ABSTRACT | This disclosure provides novel neutralizing anti-SARS-COV-2 antibodies or antigen-binding fragments thereof. The disclosed anti-SARS-COV-2 antibodies constitute a novel therapeutic strategy in protection from SARS-COV-2 infections. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 18/558066 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6841 (20170801) Peptides C07K 16/1003 (20230801) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218324 | Robins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ViaCyte, Inc. (San Diego, California) |
| ASSIGNEE(S) | ViaCyte, Inc. (San Diego, California) |
| INVENTOR(S) | Allan J. Robins (Athens, Georgia); Thomas C. Schulz (Athens, Georgia) |
| ABSTRACT | The present invention provides compositions and methods for the culture and maintenance of pluripotent stem cells. More particularly, the present invention provides for compositions and methods for culturing, maintaining, growing and stabilizing primate pluripotent stem cells in a feeder-free defined media further comprising human serum, or a soluble attachment component of the human serum, for promoting cell attachment. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/373014 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/068 (20130101) C12N 5/0606 (20130101) Original (OR) Class C12N 2500/84 (20130101) C12N 2500/98 (20130101) C12N 2501/15 (20130101) C12N 2506/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218334 | Fasano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alessio Fasano (Boston, Massachusetts); Timothy K. Lu (Cambridge, Massachusetts); Stefania Senger (Melrose, Massachusetts); Maria Eugenia Inda (Cambridge, Massachusetts) |
| ABSTRACT | Ex vivo monolayer models of human interstinal epithelia that express sensors, and methods of use thereof for evaluation of the effects of test compounds on the human gut. |
| FILED | Monday, February 05, 2024 |
| APPL NO | 18/432439 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0679 (20130101) Original (OR) Class C12N 2501/998 (20130101) C12N 2503/02 (20130101) C12N 2506/03 (20130101) C12N 2513/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) G01N 33/6803 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218342 | WANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lai-Xi WANG (Ellicott City, Maryland); Xiao ZHANG (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lai-Xi WANG (Ellicott City, Maryland); Xiao ZHANG (College Park, Maryland) |
| ABSTRACT | The present disclosure provides compounds useful for enzymatic glycan remodeling of a glycoprotein. Also provided is a method for remodeling a glycoprotein using M6P-glycan oxazolines in a one-pot deglycosylation/transglycosylation process, which may enable site selective M6P-glycan remodeling of glycoproteins to obtain homogeneous products. The remodeled glycoprotein (such as a recombinant human acid α-glucosidase) may have enhanced affinity for the CI-MPR, increased uptake by a cell, and improved therapeutic efficacy compared to the original glycoprotein. A method of treating Pompe disease using a glycan remodeled lysosomal enzyme is also provided. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 18/556642 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 17/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) C12N 9/2465 (20130101) Original (OR) Class Enzymes C12Y 302/01022 (20130101) C12Y 302/01096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218352 | Shoura et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Massa Shoura (Stanford, California); Stephen Levene (Redwood City, California); David Girata (Redwood City, California) |
| ABSTRACT | Methods are provided for the isolation and analysis of circular DNA from complex samples, based on the topology of the DNA molecule. A sample comprising DNA species is combined with a chaotropic dense salt solution. A fraction containing the circular DNA of interest is isolated and dialyzed to remove excess salt. In some embodiments salt gradients are generated by ultracentrifugation in the absence of intercalating dyes, e.g. ethidium bromide; and in the absence of protease digestion. The circular DNA thus isolated is substantially pure, e.g. greater than about 75%, greater than about 80%, greater than about 90%, greater than about 95% of DNA in the isolated fraction is comprised of circular DNA. |
| FILED | Thursday, March 07, 2024 |
| APPL NO | 18/598993 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1003 (20130101) C12N 15/1006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218362 | Fu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiang-Dong Fu (Rancho Santa Fe, California); Hao Qian (San Diego, California) |
| ABSTRACT | Provided herein is a method of reprogramming a non-neuronal cell to a neuron. Aspects of the present disclosure relate to using cell reprogramming agent suppresses the expression or activity of PTB to convert a non-neuronal cell into a neuron. Also provided herein is a method of treating neurodegenerative disease by reprogramming non-neuronal cells in vivo to functional neurons. |
| FILED | Thursday, May 25, 2023 |
| APPL NO | 18/323956 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218382 | WILLIAMS |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ALDEVRON, L.L.C. (Fargo, North Dakota) |
| ASSIGNEE(S) | ALDEVRON, L.L.C. (Fargo, North Dakota) |
| INVENTOR(S) | James A. WILLIAMS (Lincoln, Nebraska) |
| ABSTRACT | A eukaryotic replicative pUC-free minicircle expression vector is provided. The eukaryotic replicative pUC-free minicircle expression vector includes a pUC-free eukaryotic region sequence encoding a transgene of interest and comprising 5′ and 3′ ends and a ii) pUC-free spacer region of less than 500 basepairs in length linking the 5′ and 3′ ends of the eukaryotic region sequences and comprising a bacterial R6K replication origin having at least 95% sequence identity to SEQ ID NO: 11 and SEQ ID NO: 12 and a RNA selectable marker, the RNA selectable marker being an RNA-IN regulating RNA-OUT functional variant having at least 95% sequence identity to SEQ ID NO: 20 or SEQ ID NO: 22. |
| FILED | Friday, December 08, 2023 |
| APPL NO | 18/533474 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/64 (20130101) C12N 15/67 (20130101) C12N 15/79 (20130101) Original (OR) Class C12N 15/85 (20130101) C12N 2800/24 (20130101) C12N 2800/107 (20130101) C12N 2820/55 (20130101) C12N 2830/42 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) C12P 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218392 | Landau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nathaniel R. Landau (New York, New York); Takuya Tada (New York, New York) |
| ABSTRACT | Provided are composition and methods for use in prophylaxis or therapy of coronavirus infections. The compositions include an angiotensin-converting enzyme 2 (ACE2) ectodomain and a segment of an immunoglobulin Fc that is not an intact Fc region, and expression vectors encoding the same. The expression vectors include viral vectors. |
| FILED | Friday, December 29, 2023 |
| APPL NO | 18/401213 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 2317/526 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2740/15043 (20130101) C12N 2740/15071 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) Enzymes C12Y 304/17023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218394 | Bennett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Jean Bennett (Bryn Mawr, Pennsylvania); Junwei Sun (Philadelphia, Pennsylvania); Kenneth Shindler (Havertown, Pennsylvania); Devin McDougald (Philadelphia, Pennsylvania); Ahmara Gibbons Ross (Philadelphia, Pennsylvania) |
| ABSTRACT | Compositions and methods are provided for treating ocular neuropathy in a subject. In one aspect, a recombinant adeno-associated viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding NRF2. In another aspect, a recombinant adeno-associated viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding SIRT1. In desired embodiments, the subject is human, cat, dog, sheep, or non-human primate. |
| FILED | Wednesday, November 08, 2023 |
| APPL NO | 18/504261 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2710/10043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218406 | Buller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Andrew Richard Buller (Pasadena, California); Sabine Brinkmann-Chen (Alhambra, California); Michael Herger (Pasadena, California); David K. Romney (Pasadena, California); Javier Murciano Calles (Ubeda Jaen, Spain); Paul van Roye (Darmstadt, Germany) |
| ABSTRACT | This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids. |
| FILED | Thursday, December 07, 2023 |
| APPL NO | 18/533016 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 13/04 (20130101) C12P 13/227 (20130101) Original (OR) Class Enzymes C12Y 402/0102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218408 | Smolke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christina D. Smolke (Stanford, California); Stephanie Galanie (Stanford, California); Isis Trenchard (Stanford, California); Catherine Thodey (Stanford, California); Yanran Li (Stanford, California) |
| ABSTRACT | A method of epimerizing an (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid is provided. The method comprises contacting the (S)-1-benzylisoquinoline alkaloid with at least one enzyme. Contacting the (S)-1-benzylisoquinoline alkaloid with the at least one enzyme converts the (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid. |
| FILED | Monday, October 23, 2023 |
| APPL NO | 18/382850 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0071 (20130101) C12N 15/52 (20130101) C12N 15/62 (20130101) C12N 2800/22 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/12 (20130101) Original (OR) Class C12P 41/002 (20130101) Enzymes C12Y 101/01247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218435 | ZHANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | David ZHANG (Houston, Texas); Kerou ZHANG (Houston, Texas); Ping SONG (Houston, Texas) |
| ABSTRACT | Provided herein are compositions and methods for formation of amplicons having a chimeric sequence, partially derived from a target nucleic acid and partially derived from a rationally designed oligonucleotide. The provided compositions provide for high-yield, induced template switching between the target nucleic acid and the rationally designed oligonucleotide as the template during polymerase extension, achieving inheritance of information from both within only one cycle. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 18/557747 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218440 | Rasmussen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BioFire Diagnostics, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Randy P. Rasmussen (Salt Lake City, Utah); Robert John Crisp (Salt Lake City, Utah); Andrew Clinton Hemmert (Murray, Utah); Elizabeth Barker Campbell (Orem, Utah); Thomas Charles Robbins (Salt Lake City, Utah); David J. Eyre (Salt Lake City, Utah) |
| ABSTRACT | Methods and devices are provided for simultaneously amplifying a plurality of sample wells for a predetermined amount of amplification, detecting whether amplification has occurred in a first set of the wells, amplifying for an additional amount of amplification and detecting whether amplification has occurred in a second set of the wells. Methods are also provided for analyzing a target nucleic acid sequence using melt curves that were generated in a plurality of amplification cycles. |
| FILED | Tuesday, March 12, 2024 |
| APPL NO | 18/602140 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/689 (20130101) C12Q 1/705 (20130101) C12Q 1/6851 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218442 | Bignell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Illumina Cambridge Limited (Cambridge, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Helen Bignell (Cambridge, United Kingdom); Louise Fraser (Cambridge, United Kingdom); Niall Anthony Gormley (Cambridge, United Kingdom) |
| ABSTRACT | The invention relates to methods for indexing samples during the sequencing of polynucleotide templates, resulting in the attachment of tags specific to the source of each nucleic acid sample such that after a sequencing run, both the source and sequence of each polynucleotide can be determined. Thus, the present invention pertains to analysis of complex genomes (e.g., human genomes), as well as multiplexing less complex genomes, such as those of bacteria, viruses, mitochondria, and the like. |
| FILED | Friday, March 03, 2023 |
| APPL NO | 18/178256 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) C12Q 1/6855 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218448 | Lambowitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan Lambowitz (Austin, Texas); Jun Yao (Austin, Texas); Ching Kai Douglas Wu (Rockville, Maryland); Hengyi XU (Cedar Park, Texas) |
| ABSTRACT | Disclosed herein are methods and compositions related to determining one or more biomarkers in Full-Length Excised Linear Intron RNAs (FLEXI RNAs) and Intron RNA fragments. These FLEXI RNAs and Intron RNA fragments can be indicative of a specific characteristic. trait. disease. disorder or condition. FLEXI RNAs and Intron RNA fragments can be used to establish a predictive bio-marker. a diagnostic biomarker, a prognostic biomarker, or a biomarker that relates to drug interaction, drug response, or to a heritable condition. These biomarkers can then be used to treat. monitor. or inform patients. |
| FILED | Friday, April 23, 2021 |
| APPL NO | 17/920843 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218450 | SYMMANS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas); Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Yale University (New Haven, Texas) |
| INVENTOR(S) | William fraser SYMMANS (Houston, Texas); Bruno SINN (Berlin, Germany); Christos HATZIS (Guilford, Connecticut); Chunxiao FU (Pearland, Texas); Rosanna LAU (Houston, Texas) |
| ABSTRACT | Provided herein are methods of determining tumoral sensitivity to hormonal (endocrine) therapy based upon an index of estrogen receptor (ER)- and progesterone receptor (PR)-related genes, referred to as the sensitivity to endocrine therapy index (SETER/PR index), and may have additional consideration for the proportion of ER gene (ESR1) RNA transcripts that contain a mutation relative to the value of the SETER/PR index. Further provided are methods of treating breast cancer patients determined to be sensitive to an endocrine therapy by the SETER/PR index. |
| FILED | Wednesday, June 21, 2023 |
| APPL NO | 18/338974 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/138 (20130101) A61K 31/566 (20130101) A61K 31/4196 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 10/00 (20190201) G16B 25/10 (20190201) G16B 25/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218451 | SRIVASTAVA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (BETHESDA, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shiv K. SRIVASTAVA (Potomac, Maryland); Gyorgy PETROVICS (Bethesda, Maryland); Indu KOHAAR (North Potomac, Maryland) |
| ABSTRACT | The present disclosure provides gene expression profiles that are associated with prostate cancer, including certain gene expression profiles that differentiate between subjects of African and Caucasian descent and other gene expression profiles that are common to subjects of both African and Caucasian descent. The gene expression profiles can be measured at the nucleic acid or protein level and used to stratify prostate cancer based on ethnicity. The gene expression profiles can also be used to identify a subject for prostate cancer treatment. Also provided are kits for diagnosing and prognosing prostate cancer and an array comprising probes for detecting the unique gene expression profiles associated with prostate cancer in subjects of African and/or Caucasian descent. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/427083 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) G16B 25/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219289 | Skala et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Melissa C. Skala (Middleton, Wisconsin); Rebecca Schmitz (Madison, Wisconsin); Alexandra Jule Walsh (Madison, Wisconsin) |
| ABSTRACT | Devices and methods for label-free sensing of lymphocyte activation and identify are disclosed. The activation status of B cells and NK cells can be reliably determined. A general classifier capable of determining the activation status of lymphocytes having unknown identity (i.e., unknown whether a T cell, B cell, or NK cell) is disclosed. An identity classifier capable of differentiating T cells from B cells from NK cells is disclosed. A six-class classifier is disclosed which is capable of identifying both lymphocyte identity and activation status. |
| FILED | Wednesday, December 27, 2023 |
| APPL NO | 18/397844 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/149 (20240101) Original (OR) Class G01N 15/1429 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219376 | Skala et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Melissa C. Skala (Middleton, Wisconsin); Rupsa Datta (Madison, Wisconsin); Alexandra Jule Walsh (Madison, Wisconsin) |
| ABSTRACT | The present disclosure provides a new sensing device and method for determining the activation status of neutrophils. The device has an autofluorescence spectrometer and a cell analysis observation zone. A current activation status of the neutrophil cell is identified based on a current activation prediction, where the current activation prediction is computed using at least a portion of the autofluorescence data set. The current activation prediction is computed using at least two metabolic endpoints of the autofluorescence data set and at least one morphological parameter as an input. The at least two metabolic endpoints include either: reduced nicotinamide adenine dinucleotide and/or reduced nicotinamide dinucleotide phosphate (NAD(P)H) mean fluorescence lifetime (τm), NAD(P)H shortest fluorescence amplitude component (α1), and NAD(P)H shortest fluorescence lifetime component (τ1); or the NAD(P)H τm and flavin adenine dinucleotide (FAD) τm. The at least one morphological parameter includes either the solidity or the eccentricity. |
| FILED | Wednesday, January 03, 2024 |
| APPL NO | 18/403499 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/14 (20130101) G01N 33/5091 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219384 | Samavati |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lobelia Samavati (Beverly Hills, Michigan) |
| ABSTRACT | The present disclosure relates generally to compositions, methods, devices, and systems for the diagnosis of tuberculosis in a subject. Also described is the development of direct ELISA systems for detecting IgG against specific sequences, such as SEQ ID NO: 1, SEQ ID NO: 12 (TKTμ; DLSSEVATHQPIIACLP), SEQ ID NO: 3 (TKT1; GEDGPTHQPIEHLSA), or SEQ ID NO: 5 (TKT3; HDSIGLGEDGPTHQPIEHLS). |
| FILED | Friday, December 29, 2023 |
| APPL NO | 18/400897 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/25 (20130101) G01N 33/543 (20130101) G01N 33/5695 (20130101) Original (OR) Class G01N 33/6854 (20130101) G01N 2333/35 (20130101) G01N 2333/9104 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219393 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rachel Lee (Ithaca, New York); Jacob Erstling (Ithaca, New York); Joshua Hinckley (Framingham, Massachusetts); Ulrich B. Wiesner (Ithaca, New York) |
| ABSTRACT | Methods of determining the presence or absence or local concentration of an analyte in a sample or an individual or a portion thereof using ratiometric sensing and optical super-resolution microscopy (OSRM). The methods use aluminosilicate nanoparticles that can be used in OSRM. The analytes can be biologically relevant analytes, such as, for example, biologically relevant hydrogen ions, oxygen, reactive oxygen species, anions, nitric oxide, metal ions, anions, etc. The methods utilize averaging to address aluminosilicate nanoparticle homogeneity. The methods can be used in methods of treatment. |
| FILED | Friday, April 15, 2022 |
| APPL NO | 18/555647 |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 11/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/01 (20240101) G01N 15/075 (20240101) G01N 33/582 (20130101) G01N 33/587 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219403 | LITO |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York); Memorial Hospital for Cancer and Allied Diseases (New York, New York); Sloan-Kettering Institute for Cancer Research (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Piro LITO (New York, New York) |
| ABSTRACT | The present disclosure relates to methods for determining whether a cancer patient harboring a constitutively active KRAS mutation will be responsive to treatment with a KRASG12C inhibitor that selectively targets the inactive state of KRAS. These methods are based on assaying regulators of G-protein signaling (RGS) expression in the cancer patient. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 18/554176 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219410 | Cooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Livia Schiavinato Eberlin (Lafayette, Indiana); Christina Ramires Ferreira (West Lafayette, Indiana); Allison Lisa Dill (Indianapolis, Indiana); Demian R. Ifa (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis. |
| FILED | Friday, December 22, 2023 |
| APPL NO | 18/394339 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/0004 (20130101) H01J 49/0036 (20130101) H01J 49/142 (20130101) H01J 49/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219496 | Garwood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Garwood (Minneapolis, Minnesota); Efraín Torres (Minneapolis, Minnesota); Taylor Froelich (Minneapolis, Minnesota) |
| ABSTRACT | Radio frequency (“RF”) gradient based magnetic resonance imaging (“MRI”) is provided by establishing a gradient in the RF transmit (B1) field using frequency-modulated RF pulses. A difference between the time-bandwidth product of the frequency-modulated RF pulses can be varied to provide impart different phases to magnetic resonance signals, where these different phases provide phase encoding of the acquired data. The time-bandwidth product difference can be created and varied by changing the pulse duration of one frequency-modulated RF pulse relative to the other while keeping the bandwidth of the pulses constant. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 18/558062 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4616 (20130101) G01R 33/4831 (20130101) Original (OR) Class G01R 33/5617 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219501 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhixing Wang (Charlottesville, Virginia); John P. Mugler, III (Charlottesville, Virginia); Craig H. Meyer (Charlottesville, Virginia); Adrienne E. Campbell (Washington, District of Columbia) |
| ABSTRACT | Acquiring magnetic resonance imaging (MRI) data includes steps of using a computer to implement software program steps in a diffusion preparation software component and a spiral ring echo readout software component. The method implements the diffusion preparation software component by (i) applying at least a first diffusion gradient and a last diffusion gradient along a selected direction; and (ii) applying a magnitude stabilizer gradient, along said selected direction, after the last diffusion gradient. The method implements the spiral ring echo readout software component by (i) applying a rephasing gradient along said selected direction after a refocusing RF pulse; (ii) applying a dephasing gradient along said selected direction prior to a subsequent refocusing RF pulse; and (iii) acquiring spiral ring echo readout data between the refocusing RF pulse and the subsequent refocusing RF pulse. |
| FILED | Tuesday, January 02, 2024 |
| APPL NO | 18/402720 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/5617 (20130101) G01R 33/56341 (20130101) Original (OR) Class G01R 33/56509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240221868 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ruli Gao (Evanston, Illinois); Cheng-Kai Shiau (Evanston, Illinois); Lina Lu (Evanston, Illinois) |
| ABSTRACT | An analysis and computational tool, single cell nanopore sequencing analysis of Genotype-Phenotype simultaneously (scNanoGPS), to deconvolute barcoded long reads into single cells and single molecules without short reads curation nor guidance of barcode whitelist and calculate both phenotypes (gene expression, isoform) and genotypes (mutations) of same cells. |
| FILED | Thursday, December 07, 2023 |
| APPL NO | 18/531821 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) G16B 30/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240221942 | Auslander et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Noam Auslander (Philadelphia, Pennsylvania); Abdurrahman Elbasir (Philadelphia, Pennsylvania) |
| ABSTRACT | Systems and methods for identifying viral sequences in a subject of a species are provided. Sequence reads not associated with a reference genome of the species are obtained from a biological sample from the subject. At least a portion of each respective sequence read is encoded into a corresponding vector representing all or a portion of the sequence of the respective sequence read, thereby obtaining a plurality of vectors. Each sequence read is assigned a corresponding scalar model score by inputting a vector, in the plurality of vectors, corresponding to the sequence read into a model. Those sequence reads having a corresponding scalar model score that satisfies a first threshold score are selected as contig seeds. The plurality of sequence reads are aligned to these contig seeds through common k-mer sequences thereby forming a plurality of contigs which, in turn, are used to identify viral sequences in the subject. |
| FILED | Thursday, December 21, 2023 |
| APPL NO | 18/392646 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/10 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240222935 | Yun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seok-Hyun Yun (Cambridge, Massachusetts); Paul Dannenberg (Boston, Massachusetts) |
| ABSTRACT | A laser microparticle for generating laser light with high omnidirectionality, including: an optical cavity including an active gain material capable of supporting one or more lasing cavity modes: and an optical scattering element which is incorporated into the optical cavity and configured to change a radiation pattern of the one or more lasing cavity modes to increase omnidirectionality of the radiation pattern, the size of the microparticle being less than 10 pm in each dimension. |
| FILED | Friday, March 12, 2021 |
| APPL NO | 17/905806 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/1042 (20130101) H01S 5/1075 (20130101) Original (OR) Class H01S 2301/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240216208 | Mooney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dephy, Inc. (Boxborough, Massachusetts) |
| ASSIGNEE(S) | Dephy, Inc. (Boxborough, Massachusetts) |
| INVENTOR(S) | Luke Mooney (Boxborough, Massachusetts); Jean-François Duval (Boxborough, Massachusetts); Nicholas Benz (Boxborough, Massachusetts); Jonathan Cummings (Boxborough, Massachusetts); Matthew Mooney (Boxborough, Massachusetts) |
| ABSTRACT | An apparatus for a battery-powered active exoskeleton boot includes a shin pad and one or more housings. The one or more housings enclose electronic circuitry and an electric motor. The apparatus includes a battery holder coupled to the shin pad and located below the knee of the user and above the one or more housings enclosing the electronic circuitry. The apparatus includes a battery module removably affixed to the battery holder and comprising a first power connector that electrically couples to a second power connector located in the battery holder while attached to the battery holder to provide electric power to the electronic circuitry and the electric motor. The apparatus includes an output shaft coupled to the electric motor. The electronic circuitry controls delivery of power from the battery module to the electric motor to generate torque about the axis of rotation of the ankle joint of the user. |
| FILED | Monday, September 11, 2023 |
| APPL NO | 18/244802 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/00 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) Original (OR) Class Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) B25J 9/0009 (20130101) B25J 9/16 (20130101) B25J 19/005 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216892 | GIANNESCHI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Nathan C. GIANNESCHI (Wilmette, Illinois); Zofia E. SIWICKA (Evanston, Illinois); Naneki C. MCCALLUM (San Diego, California) |
| ABSTRACT | Aspects of the invention include a method of capturing target compound(s) using a capture device, the method comprising: exposing the device to an environment comprising the target compound(s); wherein the device comprises: a porous artificial melanin material comprising: one or more melanin oligomers and/or polymers; wherein the melanin oligomers and/or polymers comprise a plurality of covalently-bonded melanin base units; wherein the melanin oligomers and/or polymers are arranged to form an internal structure having a plurality of pores; wherein the porous artificial melanin material is characterized by a pore volume per mass of material greater than or equal to 0.1 cm3/g and wherein at least a portion of said pores have at least one size dimension greater than or equal to 0.5 nm; and capturing the target compound(s) via an interaction between the porous artificial melanin material and the target compound(s). |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 18/269078 |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/202 (20130101) B01D 2256/245 (20130101) B01D 2257/102 (20130101) B01D 2257/108 (20130101) B01D 2257/406 (20130101) B01D 2257/504 (20130101) B01D 2257/7025 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/262 (20130101) B01J 20/3057 (20130101) Original (OR) Class B01J 20/3208 (20130101) B01J 20/3272 (20130101) B01J 20/28069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217835 | Bard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kevin LEE (Seattle, Washington); Vincent HOLMBERG (Seattle, Washington); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Alexander Bard (Seattle, Washington); Kevin Guesang Lee (Seattle, Washington); Greg Felsted (Seattle, Washington); Vincent Holmberg (Seattle, Washington); Peter Pauzauskie (Seattle, Washington) |
| ABSTRACT | Systems, devices, materials, and methods including nanostructured gels are provided. A nanostructured gel includes a primary crystalline phase including cubic sodium yttrium fluoride, a secondary crystalline phase including cubic yttrium fluoride, and an amorphous phase including sodium ions and yttrium fluoride. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 18/558087 |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/36 (20200101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2002/72 (20130101) C01P 2002/86 (20130101) C01P 2004/04 (20130101) C01P 2004/38 (20130101) C01P 2006/12 (20130101) C01P 2006/16 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217838 | Srinivas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TDA Research, Inc (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Girish Srinivas (Broomfield, Colorado); Vinh T Nguyen (Arvada, Colorado); Steven Dietz (Englewood, Colorado) |
| ABSTRACT | A continuous hydrothermal process for producing LFP/LMFP cathode materials for lithium-ion batteries. The reactant solutions include: (1) a lithium precursor (LiOH) and a carbon source (15 wt % sucrose); (2) an iron precursor (FeSO4) and a phosphorus precursor (H3PO4); and in the case of LMFP, a manganese precursor (MnSO4) and a surfactant in solution 2. Reactant solutions are fed into a series of one or more continuous stirred tank reactors (CSTRs) at a constant flowrate. Active LFP/LMFP flows out of the CSTRs and into a collection tank, where it is cooled and depressurized. The product flows into a slurry tank, then a centrifugal separator to remove aqueous waste. The LFP/LMFP is transferred to a continuous rotary kiln for drying and sintering, and the carbon coating forms. The disclosed processes produce LFP/LMFP with small average particle size, high purity, high capacity, and high yield without any ball-milling or sieving steps. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424337 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/009 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2002/72 (20130101) C01P 2004/04 (20130101) C01P 2004/51 (20130101) C01P 2006/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218028 | Arnett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of the Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clint M. Arnett (Mahomet, Illinois); Martin A. Page (Urbana, Illinois); Donald M. Cropek (Champaign, Illinois); Ashley N. Boyd (Champaign, Illinois); Justin Lange (Mahomet, Illinois) |
| ABSTRACT | A system and method for producing a recombinant Moringa oleifera coagulant protein (MO) in Bacillus includes the expression of a recombinant nucleic acid encoding the MO protein fused or linked to a Bacillus signal peptide (SP). The nucleic acid can also be modified by codon optimization for enhanced expression of the MO protein in bacteria. The recombinant MO protein has coagulation/flocculation activity and can be used in the treatment of contaminated water, particularly drinking water. Vectors and nucleic acid constructs encoding the MO protein and SP, and host bacterial cells are also disclosed. |
| FILED | Wednesday, September 25, 2019 |
| APPL NO | 16/582436 |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Original (OR) Class C07K 2319/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 15/70 (20130101) C12N 15/75 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/19 (20210501) C12R 2001/125 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218055 | Ho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Mitchell Ho (Urbana, Maryland); Peter D. Kwong (Washington, District of Columbia); Zhijian Duan (Columbia, Maryland); Yaping Sun (New Haven, Connecticut); Sao-Fong Cheung (Rockville, Maryland); Jason J. Gorman (Lakeville, Massachusetts) |
| ABSTRACT | Single-domain monoclonal antibodies that specifically bind Lassa virus glycoprotein (GPC) are described. The single-domain antibodies (“nanobodies”) were isolated from camel (VHH) and shark variable new antigen (VNAR) phage display libraries panned against a stabilized form of the GPC trimer. The GPC-specific nanobodies, and conjugates thereof, can be used for the diagnosis and treatment of a Lassa virus infection. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 18/557741 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6841 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/543 (20130101) G01N 33/56983 (20130101) G01N 2333/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218194 | Boley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | John William Boley (Cambridge, Massachusetts); Javier M. Morales Ferrer (Allston, Massachusetts); Stephanie Flores Zopf (Newtonville, Massachusetts); Chloe Grace Kekedjian (Cambridge, Massachusetts); Ramon Enrique Sanchez Cruz (Allston, Massachusetts) |
| ABSTRACT | Methods and compositions for 3D and 4D printing inks exhibit desirable electrical and rheological properties. The compositions disclosed include a 3D printing ink employing a liquid metal emulsion and a method of creating a stretchable electronic device using the same. The compositions also include 4D printing inks and methods of tuning said inks to have desirable properties. |
| FILED | Friday, December 22, 2023 |
| APPL NO | 18/394639 |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/003 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 70/10 (20200101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/36 (20130101) C08K 3/041 (20170501) C08K 3/105 (20180101) C08K 2201/001 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/14 (20130101) C09D 11/023 (20130101) Original (OR) Class C09D 11/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218222 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Fuzhong Zhang (St. Louis, Missouri); Eugene Kim (St. Louis, Missouri) |
| ABSTRACT | Hybrid proteins are described that include an amino acid sequence with at least two zipper-forming protein sequences and at least one flexible sequence from a spider silk protein sequence, in which each of the at least one flexible sequences is positioned between each pair of the at least two zipper-forming protein sequences to form a repeated sequence. The amino acid sequence also includes at least one mussel foot protein sequence positioned at a C-terminus or an N-terminus of the alternating repeated sequence. Also described are adhesive hydrogels and methods of forming the adhesive hydrogels using the hybrid proteins described herein. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 18/043330 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/108 (20130101) Peptides C07K 14/43504 (20130101) C07K 14/43518 (20130101) C07K 2319/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 9/00 (20130101) C09J 189/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218309 | Varone et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Antonio Varone (Newton, Massachusetts); Norman Wen (Newton, Massachusetts); Daniel Levner (Brookline, Massachusetts); Richard Novak (Jamaica Plain, Massachusetts); Lori McPartlin (North Billerica, Massachusetts); Donald E. Ingber (Boston, Massachusetts); Youngjae Choe (Somerville, Massachusetts); Lian Leng (LaSalle, Canada); Justin K. Nguyen (Medford, Massachusetts) |
| ABSTRACT | A device for simulating a function of a tissue includes a first structure, a second structure, and a membrane. The first structure defines a first chamber. The first chamber includes a matrix disposed therein and an opened region. The second structure defines a second chamber. The membrane is located at an interface region between the first chamber and the second chamber. The membrane includes a first side facing toward the first chamber and a second side facing toward the second chamber. The membrane separates the first chamber from the second chamber. |
| FILED | Wednesday, March 13, 2024 |
| APPL NO | 18/604469 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 2300/069 (20130101) Apparatus for Enzymology or Microbiology; C12M 3/04 (20130101) C12M 21/08 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 25/02 (20130101) C12M 25/14 (20130101) C12M 29/10 (20130101) C12M 41/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 5/0629 (20130101) C12N 5/0656 (20130101) C12N 5/0679 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218377 | LIU |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (Augusta, Georgia) |
| ASSIGNEE(S) | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (Augusta, Georgia) |
| INVENTOR(S) | Hongyan LIU (Martinez, Georgia) |
| ABSTRACT | Bispecific aptamers having a first end that specifically binds to a first tumor specific marker, tumor antigen, or viral protein and a second end that specifically binds to a second tumor specific marker, tumor antigen, or viral protein are provide. The bispecific aptamers can be used to treat cancer or virally infected cells. Generally, the bispecific aptamers bind to two surface proteins, preferably different proteins, on the same cell. In a preferred embodiment the bispecific aptamers bind to two different tumor markers, tumor antigens, tumor specific proteins and combinations thereof. |
| FILED | Thursday, March 14, 2024 |
| APPL NO | 18/605428 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218451 | SRIVASTAVA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (BETHESDA, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shiv K. SRIVASTAVA (Potomac, Maryland); Gyorgy PETROVICS (Bethesda, Maryland); Indu KOHAAR (North Potomac, Maryland) |
| ABSTRACT | The present disclosure provides gene expression profiles that are associated with prostate cancer, including certain gene expression profiles that differentiate between subjects of African and Caucasian descent and other gene expression profiles that are common to subjects of both African and Caucasian descent. The gene expression profiles can be measured at the nucleic acid or protein level and used to stratify prostate cancer based on ethnicity. The gene expression profiles can also be used to identify a subject for prostate cancer treatment. Also provided are kits for diagnosing and prognosing prostate cancer and an array comprising probes for detecting the unique gene expression profiles associated with prostate cancer in subjects of African and/or Caucasian descent. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/427083 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) G16B 25/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218457 | RAO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aditya Manohar RAO (Stanford, California); Purvesh KHATRI (Menlo Park, California); Madeleine SCOTT (Stanford, California) |
| ABSTRACT | Methods for diagnosing active tuberculosis and progression to active tuberculosis are disclosed. In some embodiments, the method may comprise (a) obtaining a sample of RNA from a subject, e.g., a subject having latent tuberculosis and/or symptoms of active tuberculosis; and (b) measuring the amount of RNA transcripts encoded by PLAAT4, CYB561, GBP5, SMAD7, LAX1, CDKN1C, CA5B, EPHA4 and CD83 in the sample, to produce gene expression data. This data can be used for the diagnosis and to make treatment decisions. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 18/288765 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218528 | Schroer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thorsten G. Schroer (Palmdale, California); Gregory E. LeCroy (Lancaster, California); Miguel Aguila (Palmdale, California); Mayra P. Rodriguez (Lancaster, California); Tyler J. Downard (Phelan, California); Brianna L. MacLeod (Lancaster, California) |
| ABSTRACT | A process for the microfluidic electrochemical synthesis of geminal dipseudohalide or halide-pseudohalide compounds comprising the steps of pumping a solution comprising a compound of Formula I into a microfluidic electrochemical reactor in the presence of a base, one of a halide or pseudohalide salt (MY), and a mediator; applying an electrical current through the microfluidic electrochemical reactor; and performing oxidative addition to create a geminal dipseudohalide or halide-pseudohalide compound of the general Formula II |
| FILED | Tuesday, January 16, 2024 |
| APPL NO | 18/413884 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/11 (20210101) Original (OR) Class C25B 9/19 (20210101) C25B 11/091 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218563 | Iyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina A and T State University (Greensboro, North Carolina) |
| ASSIGNEE(S) | North Carolina A and T State University (Greensboro, North Carolina) |
| INVENTOR(S) | Shanthi Iyer (Greensboro, North Carolina); Jia Li (Greensboro, North Carolina); Prithviraj Deshmukh (Hillsboro, Oregon); Manish Sharma (Hillsboro, Oregon) |
| ABSTRACT | Compositions comprising Group V/III nanowires, and methods of making such nanowires are described. Some compositions comprise one or more core-shell nanowires comprising a core and a first shell surrounding or substantially surrounding the core. The core is formed from GaAs(1−y)Sby, where y=about 0.03-0.07 and the first shell is formed from GaAs(1−x)SbxN, where x=0.27-0.34. The nanowires have an average emission maximum of 1.4-1.7 μm. Some nanowires further comprise a second shell surrounding or substantially surrounding the first shell. The second shell is formed from a Group V/III material such as Ga1−mAlmAs, where m=0-0.2. Some nanowires have the structure GaAs(0.93-0.97)Sb(0.03-0.07)/GaAS(0.66-0.73)Sb(0.27-0.34)N/Ga(0.8-1)Al(0-0.2)As. |
| FILED | Monday, January 29, 2024 |
| APPL NO | 18/425387 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/02 (20130101) C30B 29/40 (20130101) C30B 29/403 (20130101) Original (OR) Class C30B 29/605 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218795 | Hayes |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Special Aerospace Services, LLC (Boulder, Colorado) |
| ASSIGNEE(S) | Special Aerospace Services, LLC (Boulder, Colorado) |
| INVENTOR(S) | Christopher Hayes (Denver, Colorado) |
| ABSTRACT | Methods and systems for manipulating surface topology of additively manufactured fluid interacting structures, such as additively manufactured heat exchangers or airfoils, and associated additively manufactured articles, are disclosed. In one aspect, an article which interacts with a fluid is imparted with surface topology features which affect performance parameters related to the fluid flow. The topological features may be sequenced, combined, intermixed, and functionally varied in size and form to locally manipulate and co-optimize multiple performance parameters at each or selectable differential lengths along a flow path. The co-optimization method may uniquely prioritize selectable performance parameters at different points along the flow path to improve or enhance overall system performance. Topological features may include design features such as dimples, fins, boundary layer disruptors, and biomimicry surface textures, and manufacturing artefacts such as surface roughness and subsurface porosity distribution and morphology. |
| FILED | Sunday, December 17, 2023 |
| APPL NO | 18/542697 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/38 (20130101) B29C 45/2612 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/14 (20130101) Original (OR) Class Jet-propulsion Plants F02K 9/60 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) F05D 2300/514 (20130101) F05D 2300/516 (20130101) Electric Digital Data Processing G06F 30/15 (20200101) G06F 30/28 (20200101) G06F 2113/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218830 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RTX Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Corey D. Anderson (East Hartford, Connecticut); Edward Boucher (New Haven, Connecticut); Rebecca R. Dunnigan (Sturbridge, Massachusetts); Nicholas Broulidakis (Vernon, Connecticut); Matthew Murakami (West Hartford, Connecticut); Daniel R. Brandt (Somerville, Massachusetts); Konrad Kuc (West Hartford, Connecticut); Victoria M. Imlach (Marlborough, Connecticut); Sushruth G. Kamath (Manchester, Connecticut); Manuel A. Casares Rivas (Hartford, Connecticut); Eric G. Leamon (Manchester, Connecticut); Adam Castles (West Hartford, Connecticut); Edmond Cheung (East Hampton, Connecticut); Kyra A. Thole-Wilson (West Hartford, Connecticut); Javier Nebero Johnson (South Glastonbury, Connecticut) |
| ABSTRACT | A gas turbine engine including a core having a compressor section fluidly connected to a combustor via a primary flowpath and a turbine section connected to the combustor via the core flow path. An assembly is disposed within the gas turbine engine and includes a first part connected to a second part via a radial stack joint. The first part includes a radially inward facing surface contacting a corresponding radially outward facing surface of the second part. A fastener protrudes through the first part and the second part and is configured to maintain the relative positions of the first part and the second part. A channel is disposed on at least one of the radially inward facing surfaces and is positioned between the fastener and a circumferential edge of the first part. The channel is connected to at least one cooling air source. |
| FILED | Wednesday, January 31, 2024 |
| APPL NO | 18/428025 |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2260/232 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219301 | MOHAMMED et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohammed Tharwat Hassan MOHAMMED (Tucson, Arizona); Dandan HUI (Tucson, Arizona); Husain ALQATTAN (Tucson, Arizona) |
| ABSTRACT | Methodology for optical switching and/or coding of information with attosecond time resolution and, in particular, binary encoding of data based on modulation of reflectivity or transmissivity of a target non-electrically-conducting material system in a strong light field. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 18/557478 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/55 (20130101) G01N 21/59 (20130101) Original (OR) Class G01N 2021/1725 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219579 | SHEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan SHEN (Germantown, Maryland); Genshe CHEN (Germantown, Maryland); Tien NGUYEN (Germantown, Maryland); Khanh PHAM (Kirtland AFB, New Mexico) |
| ABSTRACT | A global navigation satellite system (GNSS) is disclosed comprising a transmitter. The transmitter is configured to: receive a plurality of frequencies; determine a minimum frequency from the plurality of frequencies; determine a maximum frequency from the plurality of frequencies; determine a carrier from the minimum frequency and the maximum frequency; determine a set of subcarriers from the carrier and the plurality of frequencies; identify optimal radius of desired phase points to select optimal subcarriers from the set of subcarriers; determine inter-modulation terms with a minimal energy based on the optimal subcarriers; and generate multi-carrier constant envelope waveforms based on the inter-modulation terms. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/072866 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/29 (20130101) Original (OR) Class G01S 19/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219794 | Lentz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Joshua Lentz (Niceville, Florida) |
| ABSTRACT | A projector includes a beam homogenizer receiving light from a light source and creating a predetermined illumination, and a spatial light modulator including grating stages to receive the predetermined illumination. Each grating stage may include a plurality of pixels where corresponding pixels in the grating stages are aligned with one another. Each of the pixels may include a liquid crystal layer disposed between two substrates, where a pixel is switchable by applying a voltage thereto, with a grating period of the pixel selected such that, when the voltage is applied to the pixel and light is passed therethrough, optical energy from the light in plus and minus first orders is deflected toward sides of the pixel and optical energy from a zero order of the light is allowed to pass through the pixel, with a polarization state of the light maintained through the pixel. |
| FILED | Wednesday, March 13, 2024 |
| APPL NO | 18/603670 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/003 (20130101) G02B 5/18 (20130101) G02B 27/4233 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/29 (20130101) G02F 1/139 (20130101) Original (OR) Class G02F 1/292 (20130101) G02F 1/1313 (20130101) G02F 1/13363 (20130101) G02F 1/13439 (20130101) G02F 1/13471 (20130101) G02F 1/133631 (20210101) G02F 1/133711 (20130101) G02F 1/133757 (20210101) G02F 1/133788 (20130101) G02F 2203/04 (20130101) G02F 2203/07 (20130101) G02F 2203/22 (20130101) G02F 2203/24 (20130101) G02F 2203/48 (20130101) Pictorial Communication, e.g Television H04N 9/3164 (20130101) H04N 9/3167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219951 | MONROE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher MONROE (Ellicott City, Maryland); Jiehang ZHANG (College Park, Maryland); David WONG-CAMPOS (Hyattsville, Maryland); Antonios KYPRIANIDIS (Takoma, Maryland); Patrick Michael BECKER (College Park, Maryland) |
| ABSTRACT | The disclosure describes an adaptive and optimal imaging of individual quantum emitters within a lattice or optical field of view for quantum computing. Advanced image processing techniques are described to identify individual optically active quantum bits (qubits) with an imager. Images of individual and optically-resolved quantum emitters fluorescing as a lattice are decomposed and recognized based on fluorescence. Expected spatial distributions of the quantum emitters guides the processing, which uses adaptive fitting of peak distribution functions to determine the number of quantum emitters in real time. These techniques can be used for the loading process, where atoms or ions enter the trap one-by-one, for the identification of solid-state emitters, and for internal state-detection of the quantum emitters, where each emitter can be fluorescent or dark depending on its internal state. This latter application is relevant to efficient and fast detection of optically active qubits in quantum simulations and quantum computing. |
| FILED | Friday, April 28, 2023 |
| APPL NO | 18/309559 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) G01J 2001/4247 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Computing Devices; G06E 3/005 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/66977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240220835 | Gorshkov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexey Vyacheslavovich Gorshkov (Potomac, Maryland); Adam Ethan Ehrenberg (University Park, Maryland); Jacob Allen Bringewatt (Hyattsville, Maryland) |
| ABSTRACT | Measuring a single linear function q(θ1, θ2, . . . , θd) of unknown parameters {θ1, θ2, . . . , θd} with a quantum sensor network while using the minimum amount of entanglement includes: providing a plurality of d quantum sensors, wherein each quantum sensor j is configured for measuring θj; preparing the plurality of quantum sensors in a probe quantum state with a minimum amount of entanglement, such that the amount of entanglement is the smallest amount of entanglement that gives the same optimal measurement of the linear function q(θ1, θ2, . . . , θd) as if the amount of entanglement was not restricted; exposing the plurality of quantum sensors to the set of unknown parameters; measuring the plurality of quantum sensors; and calculating the single linear function q(θ1, θ2, . . . , θd) from the measurements of the plurality of quantum sensors with robust phase estimation. |
| FILED | Friday, August 11, 2023 |
| APPL NO | 18/232890 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) Original (OR) Class G06N 10/70 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240220839 | Levonian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David S. Levonian (Cambridge, Massachusetts); Ralf RIEDINGER (Cambridge, Massachusetts); Bartholomeus MACHIELSE (Cambridge, Massachusetts); Mihir Keshav BHASKAR (Cambridge, Massachusetts); Mikhail D. LUKIN (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods are disclosed for optically entangling distinguishable qubits. A system can include a first qubit having an optical transition at a first qubit frequency, a second qubit having an optical transition at a second qubit frequency, and a light source producing a first light beam having at least a first frequency. An interferometer can be configured to convert the first light beam into at least one second light beam, to provide the at least one second light beam to the first qubit and the second qubit, and to provide an output light signal. The interferometer can include a first optical modulator that converts the first light beam into the at least one second light beam, and a second optical modulator that produces the output light signal from the at least one second light beam. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 18/557493 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240222882 | Kaddour et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Abdul-Sattar Kaddour (Miami, Florida); Stavros Georgakopoulos (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Abdul-Sattar Kaddour (Miami, Florida); Stavros Georgakopoulos (Miami, Florida) |
| ABSTRACT | Antenna arrays with three-dimensional (3D) conformal radiating elements are provided, as well as methods of manufacturing and methods of using the same. An array can include a ground plane and a plurality of unit cells disposed thereon. Each unit cell can include a 3D conformal radiating element. The 3D conformal radiating elements can be, for example, patches (e.g., circular 3D patches), dipoles, or loops, and each radiating element is conformal on a hemispherical shape. |
| FILED | Tuesday, December 05, 2023 |
| APPL NO | 18/529732 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 5/48 (20150115) Original (OR) Class H01Q 15/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240223697 | BALASUBRAMANIYAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| INVENTOR(S) | Vijay BALASUBRAMANIYAN (Atlanta, Georgia); Mustaque AHAMAD (Atlanta, Georgia); Patrick Traynor (Decatur, Georgia); Michael Thomas HUNTER (Atlanta, Georgia); Aamir POONAWALLA (Atlanta, Georgia) |
| ABSTRACT | Various embodiments of the invention are detection systems and methods for detecting call provenance based on call audio. An exemplary embodiment of the detection system can comprise a characterization unit, a labeling unit, and an identification unit. The characterization unit can extract various characteristics of networks through which a call traversed, based on call audio. The labeling unit can be trained on prior call data and can identify one or more codecs used to encode the call, based on the call audio. The identification unit can utilize the characteristics of traversed networks and the identified codecs, and based on this information, the identification unit can provide a provenance fingerprint for the call. Based on the call provenance fingerprint, the detection system can identify, verify, or provide forensic information about a call audio source. |
| FILED | Thursday, February 08, 2024 |
| APPL NO | 18/436668 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0829 (20130101) H04L 65/1076 (20130101) Telephonic Communication H04M 1/68 (20130101) H04M 3/2281 (20130101) Original (OR) Class H04M 7/0078 (20130101) H04M 2203/558 (20130101) H04M 2203/6027 (20130101) H04M 2203/6045 (20130101) Wireless Communication Networks H04W 12/02 (20130101) H04W 12/12 (20130101) H04W 12/63 (20210101) H04W 12/65 (20210101) H04W 24/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240216902 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ying-Bing Jiang (Albuquerque, New Mexico); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yifeng Wang (Sarasota, Florida); Ying-Bing Jiang (Albuquerque, New Mexico) |
| ABSTRACT | A transparent ceramic substrate is covered by a photocatalyst layer, at least partially. The photocatalyst layer includes a semiconductor material that, upon exposure to electromagnetic radiation, forms a plurality of electrons and a plurality of holes that remain confined to the photocatalyst layer. The transparent ceramic substrate has a diameter that is larger than the wavelength of the electromagnetic radiation for light trapping. |
| FILED | Friday, March 15, 2024 |
| APPL NO | 18/606360 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/084 (20130101) A61L 2/088 (20130101) A61L 9/205 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) B01J 35/39 (20240101) Original (OR) Class B01J 35/51 (20240101) B01J 35/612 (20240101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/725 (20130101) C02F 2305/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216906 | Jayne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mitegen, LLC (Ithaca, New York) |
| ASSIGNEE(S) | Mitegen, LLC (Ithaca, New York) |
| INVENTOR(S) | Richard Jayne (Lansing, New York); David Closs (Freeville, New York); Benjamin A. Apker (Barton, New York); Robert E. Thorne (Ithaca, New York) |
| ABSTRACT | Humidified sample preparation station for serial crystallography according to one embodiment is a humidified enclosure that delivers relative humidities above 95% and preferably above 97% in standard operation, and that can allow microscope observation of samples within. Humidified sample preparation station for serial crystallography can be used for preparation of protein crystal samples for examination using X-rays and for protein structure determination by X-ray crystallography, involving addition of liquid to the sample and removal of liquid from the sample using vacuum or suction. |
| FILED | Thursday, January 25, 2024 |
| APPL NO | 18/422738 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 1/025 (20130101) Original (OR) Class B01L 3/508 (20130101) B01L 7/00 (20130101) B01L 2300/18 (20130101) B01L 2300/123 (20130101) B01L 2300/0663 (20130101) Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) G02B 27/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216973 | Whalen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott A. Whalen (West Richland, Washington); Darrell R. Herling (Kennewick, Washington); Xiao Li (Richland, Washington); MD Reza-E-Rabby (West Richland, Washington); Brandon Scott Taysom (West Richland, Washington); Glenn J. Grant (Benton City, Washington); Vineet V. Joshi (Richland, Washington); Rajib Kalsar (Richland, Washington); Tianhao Wang (Richland, Washington) |
| ABSTRACT | The present disclosure provides methods for preparing an extruded product from a solid billet. The methods can include providing an as-cast billet for extrusion; applying a simultaneous rotational shear and axial extrusion force to the as-cast billet to plasticize the as-cast billet; and extruding the plasticized as-cast billet with an extrusion die to form an extruded product. Methods for preparing extruded products from billets can also include: providing a billet for extrusion; while maintaining a majority of the billet below 100° C., applying a simultaneous rotational shear and axial extrusion force to one end of the billet to plasticize the one end of the billet; and extruding the plasticized one end of the billet with an extrusion die to form an extruded product. Methods for preparing an extruded product from a billet can also include providing a billet for extrusion; applying a simultaneous rotational shear and axial extrusion force to the billet to plasticize the billet; extruding the plasticized billet with an extrusion die to form an extruded product; and artificially aging the extruded product for less than the ASTM recommended amount of time. |
| FILED | Monday, January 29, 2024 |
| APPL NO | 18/426042 |
| CURRENT CPC | Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material B21C 23/218 (20130101) Original (OR) Class Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 37/16 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/001 (20130101) B23K 2103/10 (20180801) B23K 2103/15 (20180801) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/04 (20130101) C22F 1/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217016 | Mondal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Sudeepta Mondal (Windham, Connecticut); Soumalya Sarkar (Manchester, Connecticut); John Joseph Gangloff (Middletown, Connecticut); Wenping Zhao (Glastonbury, Connecticut); Lei Xing (South Windsor, Connecticut) |
| ABSTRACT | A system having a set of instructions executable by the system for multi-source machine learning modeling framework for process property mapping of thermoplastic composite manufacturing, the set of instructions comprising: an instruction to select a surrogate machine learning model from a suite of machine learning networks; an instruction to involve uncertainty quantification associated with predictions which provide a quantified estimate of how much the machine learning model can be trusted; an instruction to provide multi-physics process model output to the machine learning model; an instruction to provide heterogeneous data sources for use by the machine learning model; an instruction to determine estimates of optimal process parameters employing budget-constrained multi-fidelity process optimization; an instruction for deployment the multi-source machine learning model in the implementation of carbon fiber reinforced thermoplastic polymer induction welding; and an instruction to perform induction welding with an optimized recipe. |
| FILED | Wednesday, December 28, 2022 |
| APPL NO | 18/089911 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 9/0953 (20130101) Original (OR) Class Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/0265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217180 | McLeod et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (DENVER, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert R. McLeod (Boulder, Colorado); Charles M. Rackson (, None) |
| ABSTRACT | Systems and methods for improved volumetric additive manufacturing (VAM) are described herein. In some aspects of the present disclosure, approaches to VAM image-computation are provided that algebraically optimizes directly on the structure to be printed, instead of on the set of external projection images. These approaches provide multiple advantages including improved reconstruction fidelity, simplicity, flexibility, and robust convergence to a desirable reconstruction, regardless of initial image-set guess. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 18/288713 |
| CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 7/08 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) B29C 64/241 (20170801) B29C 64/393 (20170801) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217835 | Bard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kevin LEE (Seattle, Washington); Vincent HOLMBERG (Seattle, Washington); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Alexander Bard (Seattle, Washington); Kevin Guesang Lee (Seattle, Washington); Greg Felsted (Seattle, Washington); Vincent Holmberg (Seattle, Washington); Peter Pauzauskie (Seattle, Washington) |
| ABSTRACT | Systems, devices, materials, and methods including nanostructured gels are provided. A nanostructured gel includes a primary crystalline phase including cubic sodium yttrium fluoride, a secondary crystalline phase including cubic yttrium fluoride, and an amorphous phase including sodium ions and yttrium fluoride. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 18/558087 |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/36 (20200101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2002/72 (20130101) C01P 2002/86 (20130101) C01P 2004/04 (20130101) C01P 2004/38 (20130101) C01P 2006/12 (20130101) C01P 2006/16 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218028 | Arnett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of the Army (Alexandria, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clint M. Arnett (Mahomet, Illinois); Martin A. Page (Urbana, Illinois); Donald M. Cropek (Champaign, Illinois); Ashley N. Boyd (Champaign, Illinois); Justin Lange (Mahomet, Illinois) |
| ABSTRACT | A system and method for producing a recombinant Moringa oleifera coagulant protein (MO) in Bacillus includes the expression of a recombinant nucleic acid encoding the MO protein fused or linked to a Bacillus signal peptide (SP). The nucleic acid can also be modified by codon optimization for enhanced expression of the MO protein in bacteria. The recombinant MO protein has coagulation/flocculation activity and can be used in the treatment of contaminated water, particularly drinking water. Vectors and nucleic acid constructs encoding the MO protein and SP, and host bacterial cells are also disclosed. |
| FILED | Wednesday, September 25, 2019 |
| APPL NO | 16/582436 |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Original (OR) Class C07K 2319/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 15/70 (20130101) C12N 15/75 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/19 (20210501) C12R 2001/125 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218144 | Smalyukh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ivan I. Smalyukh (Boulder, Colorado); Andrew Johnston Hess (Louisville, Colorado); Quingkun Liu (Boulder, Colorado); Joshua A. De La Cruz (Denver, Colorado); Blaise Fleury (Boulder, Colorado); Eldho Abraham (Boulder, Colorado); Bohdan Senyuk (Boulder, Colorado); Vladyslav Cherpak (Westminster, Colorado) |
| ABSTRACT | Disclosed are cellulose-based flexible aerogels and xerogels containing bacterial cellulose nanorods, ribbons, fibers, and the like, wherein the gels have tunable optical, heat transfer, and stiffness properties. Further disclosed are highly transparent and flexible cellulose nanofiber-polysiloxane composite aerogels featuring enhanced mechanical robustness, tunable optical anisotropy, and low thermal conductivity. |
| FILED | Tuesday, March 12, 2024 |
| APPL NO | 18/603094 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 9/28 (20130101) Original (OR) Class C08J 2201/026 (20130101) C08J 2201/0504 (20130101) C08J 2205/026 (20130101) C08J 2205/028 (20130101) C08J 2301/02 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/544 (20130101) C08K 7/02 (20130101) C08K 2201/011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218271 | Timko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Timko (Arlington, Massachusetts); Alex R. Maag (Whitinsville, Massachusetts); Elizabeth Belden (, None); Geoffrey A. Tompsett (Shrewsbury, Massachusetts); Andrew R. Teixeira (Boylston, Massachusetts); Aidin Panahi (Worcester, Massachusetts); Andrew Charlebois (Worcester, Massachusetts); Skyler Kauffman (Worcester, Massachusetts) |
| ABSTRACT | A waste stream of organic matter such as sewage, plant and plastic matter is received for recycling and treated with high temperature and pressure to generate useful organic products such as bio-oil and gas. Byproducts such as char and an aqueous phase including water can be selectively recycled or beingly discarded. An oxidant added to a reactor containing waste from the waste stream facilitates an autothermal reaction under the temperature and pressure applied to the reactor, boosting the temperature slightly from the reactions therein. The reactor generates useful hydrocarbons such as bio-oil resulting from disruption of organic bonds. A combination of oxidation and radical initiation results from the oxidant, and provides an increased yield of bio-oil while decreasing char when compared to temperature and pressure alone. A stoichiometric quantity of the oxidant limits complete conversion of carbon into carbon dioxide by limiting available oxygen and therefore favoring hydrocarbon formation. |
| FILED | Thursday, December 14, 2023 |
| APPL NO | 18/540345 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 11/06 (20130101) Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 53/02 (20130101) C10B 53/07 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 69/06 (20130101) Original (OR) Class C10G 2300/80 (20130101) C10G 2300/1003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218526 | Atwater et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Harry A. Atwater (South Pasadena, California); Chengxiang Xiang (San Marino, California); Zhiyuan Qi (Pasadena, California); Monica Hwang (Torrance, California); Richard F. Zheng (Lake Oswego, Oregon); Wei Wang (Richland, Washington); Soowhan Kim (Richland, Washington); Ryan Benavides (Pasadena, California); Daniel R. Bottenus (Richland, Washington) |
| ABSTRACT | Systems and methods for generating high-pressure hydrogen are described. The hydrogen generation systems include hybrid electrolyzer systems and catalytic compression systems. The systems can directly generate gaseous hydrogen at a pressure of at least 700 bar. |
| FILED | Friday, December 15, 2023 |
| APPL NO | 18/542516 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) Original (OR) Class C25B 9/15 (20210101) C25B 9/23 (20210101) C25B 11/032 (20210101) C25B 11/052 (20210101) C25B 11/063 (20210101) C25B 11/065 (20210101) C25B 11/075 (20210101) C25B 11/081 (20210101) C25B 11/085 (20210101) C25B 15/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218544 | NAGY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Sayed Youssef Sayed NAGY (Troy, Michigan); Jeffrey David CAIN (Royal Oak, Michigan); Nicholas Paul William PIECZONKA (Windsor, Ontario, Canada); Thomas E. MOYLAN (Dearborn Heights, Michigan); Yuntao GU (Farmington Hills, Michigan) |
| ABSTRACT | A method for extracting lithium from lithium-based materials to be recycled using an electrochemical reactor includes applying a voltage to a current collector at least partially disposed in an electrolyte carried by the electrochemical reactor, where the lithium-based materials including lithium to be recovered is disposed in the electrolyte and lithium ions move from the lithium-based material towards the current collector upon application of the voltage. In certain variations, the method may also include, prior to the application of the voltage, applying a current to the current collector. |
| FILED | Thursday, December 22, 2022 |
| APPL NO | 18/087410 |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/02 (20130101) Original (OR) Class C25C 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218550 | Naskar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amit K. Naskar (Knoxville, Tennessee); Zeyang Yu (Knoxville, Tennessee); Xinzhang Zhou (Knoxville, Tennessee); Christopher C. Bowland (Knoxville, Tennessee) |
| ABSTRACT | A surface-modified carbon fiber composition comprising: (i) a carbon fiber having an outer surface, a width of at least 1 micron, and a length-to-width aspect ratio of at least 1000; and (ii) an amine-containing polymer coating bonded to the outer surface of the carbon fiber, wherein the amine-containing polymer contains at least one of primary and secondary amino groups. A method for producing the coated carbon fiber comprises: immersing an uncoated carbon fiber in an electrolyte solution containing a dissolved amount of an amine-containing polymer containing at least one of primary and secondary amino groups while the uncoated carbon fiber is connected to a negatively charged electrode and positioned adjacent to a positively charged electrode in the electrolyte solution to result in the electrodeposition of a coating of the amine-containing polymer on the uncoated carbon fiber. Also described herein are carbon fiber-polymer composites and methods of producing them. |
| FILED | Wednesday, September 27, 2023 |
| APPL NO | 18/373628 |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/48 (20130101) C25D 5/54 (20130101) C25D 9/02 (20130101) Original (OR) Class C25D 21/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219420 | MITTLEMAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel MITTLEMAN (Providence, Rhode Island); Angela PIZZUTO (Norwich, Connecticut) |
| ABSTRACT | A method for scanning near-field optical microscopy comprises illuminating an apertureless atomic force microscopy (AFM) probe with electromagnetic energy having a frequency in the Terahertz range, where the sample under observation includes a dielectric layer having a thickness greater than the radius of the tip of the AFM probe. A system for scanning near-field optical microscopy comprises a collimated light source for emitting collimated light, a photoconductive antenna for converting collimated light into electromagnetic energy having a frequency in the Terahertz range, an AFM probe, a sample comprising a dielectric layer, the dielectric layer having a thickness greater than the radius of the probe tip; and a detector configured to detect energy that has interacted with the sample. |
| FILED | Thursday, January 04, 2024 |
| APPL NO | 18/404780 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/30 (20130101) Original (OR) Class G01Q 60/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219549 | HENZE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado); IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa); UNIVERSITY OF WASHINGTON (Seattle, Washington); ALLIANCE FOR SUSTAINABLE ENERGY LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregor P. HENZE (Boulder, Colorado); Joshua R. SMITH (Seattle, Washington); Soumik SARKAR (Ames, Iowa); Anthony J. FLORITA (Goldon, Colorado); Margarite JACOBY (Boulder, Colorado); Mohamadtaghi Katanbaf NEZHAD (Seattle, Washington); Ali SAFFARI (Seattle, Washington); Sin Yong TAN (Ames, Iowa) |
| ABSTRACT | An integrated occupancy sensing system includes one or more radio frequency identification (RFID) sensor nodes and one or more base station units. Each of the one or more RFID sensor nodes includes at least one of (1) an image sensor, (2) an acoustic energy sensor, (3) a temperature sensor, (4) an illuminance sensor, or (5) a relative humidity sensor. Each of the one or more base station units is configured to be connected to a power source to emit a continuous wave carrier signal and to receive a reflected signal. Each of the one or more RFID sensor nodes is configured to receive and reflect the continuous wave carrier signal. In response to receiving the reflected signal from the one or more RFID sensor nodes, at least one of the base station units is configured to infer the likelihood of human occupancy in the building. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 18/557369 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/04 (20130101) Original (OR) Class G01S 13/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219585 | Warren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EXERGYN LTD. (Dublin 11, Ireland) |
| ASSIGNEE(S) | EXERGYN LTD. (Dublin 11, Ireland) |
| INVENTOR(S) | Keith Warren (Dublin 11, Ireland); Matthieu Morhan (Dublin 11, Ireland); Fintan McDonnell (Dublin 11, Ireland); Robert Kelly (Dublin 11, Ireland); Christopher English (Dublin 11, Ireland); Laura Fox (Dublin 11, Ireland); Kevin O'Toole (Dublin 11, Ireland); Michael Langan (Dublin 11, Ireland) |
| ABSTRACT | Radiation monitoring devices and associated methods are described. According to one aspect, a radiation monitoring device includes a housing configured to pass radiation emitted from a radiological source located in proximity to the radiation monitoring device, a radiation detector configured to receive the radiation emitted from the radiological source and to generate information regarding the radiation, and communications circuitry configured to communicate the information regarding the radiation in a plurality of communications at a plurality of different moments in time externally of the radiation monitoring device. |
| FILED | Tuesday, April 27, 2021 |
| APPL NO | 17/921541 |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/175 (20130101) Original (OR) Class G01T 7/00 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 1/085 (20130101) G21F 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240220839 | Levonian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David S. Levonian (Cambridge, Massachusetts); Ralf RIEDINGER (Cambridge, Massachusetts); Bartholomeus MACHIELSE (Cambridge, Massachusetts); Mihir Keshav BHASKAR (Cambridge, Massachusetts); Mikhail D. LUKIN (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods are disclosed for optically entangling distinguishable qubits. A system can include a first qubit having an optical transition at a first qubit frequency, a second qubit having an optical transition at a second qubit frequency, and a light source producing a first light beam having at least a first frequency. An interferometer can be configured to convert the first light beam into at least one second light beam, to provide the at least one second light beam to the first qubit and the second qubit, and to provide an output light signal. The interferometer can include a first optical modulator that converts the first light beam into the at least one second light beam, and a second optical modulator that produces the output light signal from the at least one second light beam. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 18/557493 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240221225 | Chambers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Teres Technologies, Inc. (Loveland, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Chambers (Livermore, California); Jeffrey Edward Mast (Loveland, Colorado) |
| ABSTRACT | Devices, methods and techniques related to image rendering for ground-penetrating radar (GPR) systems are disclosed. In one example aspect, a method for producing one or more images associated with a GPR includes receiving information representative of signals received by the GPR, determining at least three frequency bands associated with the received information, assigning color values to the received information corresponding to the at least three frequency bands, and generating a color image for the one or more objects by combining the received information in all of the at least three frequency bands together such that the color values in the color image indicate a size of the one or more objects, a depth at which the one or more objects is buried underground, or an electrical permittivity of the one or more objects. |
| FILED | Friday, December 30, 2022 |
| APPL NO | 18/148757 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/885 (20130101) Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 7/90 (20170101) Original (OR) Class G06T 2200/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240222101 | Hubbard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Donald Danforth Plant Science Center (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Allen Hubbard (St. Louis, Missouri); Shrikaar Kambhampati (St. Louis, Missouri); Brad Evans (St. Louis, Missouri) |
| ABSTRACT | Systems and methods for amplification and detection of metabolite signals are provided. A plurality of files containing m/z signal intensities may be captured by a mass spectrometer. Each file of m/z signal intensities may include signals associated with mass measurements of compounds in a respective sample. The datasets of the chromatograms may be combined into a merged spectra of m/z signal intensities. A concentration of signals may be identified in the merged chromatogram as following a specified statistical distribution and determined to be indicative of a metabolite when the concentration of signals corresponds to one or more mass measurements associated with a metabolite and an isotopologue of the metabolite. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 18/577578 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240222541 | Schneider et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Devin Schneider (Danville, California); Lars F. Voss (Livermore, California); Noah Patrick Allen (Oakland, California); Caitlin Anne Chapin (Fremont, California); Laura Leos (Livermore, California); Alexander Peter Povilus (Livermore, California); Sara Harrison (Livermore, California); John Berns Lancaster (Livermore, California) |
| ABSTRACT | Devices, methods and techniques related to photoconductive switches using diamond are disclosed. In one example aspect, a photoconductive apparatus includes a diamond layer positioned to receive a light. The diamond layer is doped with nitrogen. The apparatus also includes a first electrode coupled to the diamond layer to provide a first electrical contact for the diamond layer, and a second electrode coupled to the diamond layer to provide a second electrical contact for the diamond layer and configured to reflect the light back to the diamond layer. The first electrode and the second electrode are configured to establish an electric field across the diamond layer in response to receiving the light. |
| FILED | Tuesday, December 26, 2023 |
| APPL NO | 18/396223 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/09 (20130101) Original (OR) Class H01L 31/0288 (20130101) H01L 31/02327 (20130101) H01L 31/022466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240222609 | Whittingham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | M. Stanley Whittingham (Vestal, New York); Jia Ding (Binghamton, New York) |
| ABSTRACT | An electrode comprising a space group Pna21 VOPO4 lattice, capable of electrochemical insertion and release of alkali metal ions, e.g., sodium ions. The VOPO4 lattice may be formed by solid phase synthesis of KVOPO4, milled with carbon particles to increase conductivity. A method of forming an electrode is provided, comprising milling a mixture of ammonium metavanadate, ammonium phosphate monobasic, and potassium carbonate; heating the milled mixture to a reaction temperature, and holding the reaction temperature until a solid phase synthesis of KVOPO4 occurs; milling the KVOPO4 together with conductive particles to form a conductive mixture of fine particles; and adding binder material to form a conductive cathode. A sodium ion battery is provided having a conductive NaVOPO4 cathode derived by replacement of potassium in KVOPO4, a sodium ion donor anode, and a sodium ion transport electrolyte. The VOPO4, preferably has a volume greater than 90 Å3 per VOPO4. |
| FILED | Monday, February 05, 2024 |
| APPL NO | 18/432831 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 31/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 14/18 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/32 (20130101) C08K 2003/328 (20130101) Compositions of Macromolecular Compounds C08L 9/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 127/06 (20130101) C09D 127/16 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/381 (20130101) Original (OR) Class H01M 4/622 (20130101) H01M 4/623 (20130101) H01M 4/625 (20130101) H01M 4/5825 (20130101) H01M 10/054 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240223000 | Heath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); The Board of Regents of the University of Texas System (Austin, Texas); Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason E. Heath (Edgewood, New Mexico); Gungor Didem Beskardes (Albuquerque, New Mexico); Wallace McAliley (Golden, Colorado); Chester J. Weiss (Sandia Park, New Mexico); Mohsen Ahmadian-Tehrani (Austin, Texas); David T. Chapman (Austin, Texas); Leela Arava (Detroit, Michigan) |
| ABSTRACT | Autonomous wireless sensors in subsurface environments can be charged while present in the subsurface environment to allow the sensors to measure and wirelessly transmit measurements. The sensors rely upon a contrast agent to provide a power flow path to the sensors. |
| FILED | Thursday, January 11, 2024 |
| APPL NO | 18/409972 |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/267 (20130101) E21B 47/06 (20130101) E21B 47/07 (20200501) E21B 47/13 (20200501) E21B 49/00 (20130101) E21B 49/0875 (20200501) E21B 2200/20 (20200501) Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 21/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/02 (20130101) Original (OR) Class H02J 50/001 (20200101) H02J 50/80 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240224549 | ZHU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kai ZHU (Littleton, Colorado); Fei ZHANG (Tianjin, China PRC) |
| ABSTRACT | The present disclosure relates to a composition that includes a first layer that includes a perovskite and a second layer that includes a perovskitoid, where the perovskite has a first crystalline structure defined by ABX3, the perovskitoid has a second crystalline structure defined by A′B2X6, where A is a first cation, B is a second cation, X is an anion, and A′ is a third cation having either a 1+ charge or a 2+ charge. |
| FILED | Tuesday, May 24, 2022 |
| APPL NO | 18/558473 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 19/005 (20130101) Organic electric solid-state devices H10K 30/40 (20230201) Original (OR) Class H10K 85/50 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20240215590 | Yoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Antithesis Foods Inc. (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Antithesis Foods Inc. (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ashton Yoon (Philadelphia, Pennsylvania); Jason Goodman (Philadelphia, Pennsylvania); Alexandra Hall (Philadelphia, Pennsylvania) |
| ABSTRACT | A system and method for the production of doughs and products using textured pulse proteins, including legume-based crunchy snack foods, said method comprising the steps of: homogenization of ingredients in the form of dry feed powders, mixing and hydration of powders with liquid ingredients to form a dough, forming of the dough into form factors, drying and expansion of the form factors to develop texture and shelf stability, and cooling. |
| FILED | Monday, March 18, 2024 |
| APPL NO | 18/608783 |
| CURRENT CPC | Treatment, e.g Preservation, of Flour or Dough, e.g by Addition of Materials; Baking; Bakery Products; Preservation Thereof A21D 2/266 (20130101) Original (OR) Class A21D 2/362 (20130101) A21D 8/02 (20130101) A21D 10/002 (20130101) A21D 13/06 (20130101) A21D 13/045 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240216285 | Wang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Ya Wang (Los Altos, California) |
| ABSTRACT | In an embodiment, the present disclosure pertains to a nanocarrier having a shell and a core disposed within the shell. In some embodiments, the shell includes a functionalized surface. In an additional embodiment, the present disclosure pertains to a method of drug delivery. In general, the method includes administering a nanocarrier to a subject, targeting, by the nanocarrier, an area in the subject, and releasing a composition having the drug to the area. In some embodiments, the nanocarrier has a shell and a core disposed within the shell. In some embodiments, the shell includes a functionalized surface. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 18/288289 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5094 (20130101) Original (OR) Class A61K 9/5146 (20130101) A61K 31/203 (20130101) A61K 41/0042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217180 | McLeod et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (DENVER, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert R. McLeod (Boulder, Colorado); Charles M. Rackson (, None) |
| ABSTRACT | Systems and methods for improved volumetric additive manufacturing (VAM) are described herein. In some aspects of the present disclosure, approaches to VAM image-computation are provided that algebraically optimizes directly on the structure to be printed, instead of on the set of external projection images. These approaches provide multiple advantages including improved reconstruction fidelity, simplicity, flexibility, and robust convergence to a desirable reconstruction, regardless of initial image-set guess. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 18/288713 |
| CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 7/08 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) B29C 64/241 (20170801) B29C 64/393 (20170801) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217835 | Bard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kevin LEE (Seattle, Washington); Vincent HOLMBERG (Seattle, Washington); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Alexander Bard (Seattle, Washington); Kevin Guesang Lee (Seattle, Washington); Greg Felsted (Seattle, Washington); Vincent Holmberg (Seattle, Washington); Peter Pauzauskie (Seattle, Washington) |
| ABSTRACT | Systems, devices, materials, and methods including nanostructured gels are provided. A nanostructured gel includes a primary crystalline phase including cubic sodium yttrium fluoride, a secondary crystalline phase including cubic yttrium fluoride, and an amorphous phase including sodium ions and yttrium fluoride. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 18/558087 |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/36 (20200101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2002/72 (20130101) C01P 2002/86 (20130101) C01P 2004/04 (20130101) C01P 2004/38 (20130101) C01P 2006/12 (20130101) C01P 2006/16 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217886 | Watkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James J. Watkins (South Hadley, Massachusetts); Dong-Po Song (Rizhao, China PRC); Wenhao Li (Sunderland, Massachusetts) |
| ABSTRACT | Various embodiments disclosed relate to a method of forming a composite including a carbon composite structure. The method includes disposing a precursor composition on a substrate. The composition includes a porogen component, a carbon component, and a catalyst component. The method further includes irradiating the precursor composition to form the carbon composite structure. |
| FILED | Thursday, March 14, 2024 |
| APPL NO | 18/605621 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/06 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/83 (20130101) C04B 35/524 (20130101) C04B 35/528 (20130101) C04B 35/532 (20130101) C04B 38/02 (20130101) C04B 38/0022 (20130101) Original (OR) Class C04B 2111/0081 (20130101) C04B 2111/00853 (20130101) C04B 2235/5264 (20130101) C04B 2235/5454 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/043 (20130101) H01M 4/049 (20130101) H01M 4/133 (20130101) H01M 4/0471 (20130101) H01M 4/587 (20130101) H01M 4/1393 (20130101) H01M 6/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218109 | Mhatre et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sampanna V. Mhatre (Newark, Delaware); Jignesh S. Mahajan (Newark, Delaware); Thomas H. Epps,, III (Bear, Delaware); LaShanda T. J. Korley (Middletown, Delaware) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Sampanna V. Mhatre (Newark, Delaware); Jignesh S. Mahajan (Newark, Delaware); Thomas H. Epps,, III (Bear, Delaware); LaShanda T. J. Korley (Middletown, Delaware) |
| ABSTRACT | Disclosed herein are bio-derivable polyhydroxyurethanes, methods of making them, compositions comprising the same, and articles comprising such compositions. The bio-derivable polyhydroxyurethane comprises in polymerized form at least one polymerizable lignin-derivable cyclic carbonate monomer, and one or more polymerizable amine crosslinkers, each comprising two or more primary amines, such that at least one of the one or more polymerizable amine crosslinkers comprises three primary amines. The bio-derivable polyhydroxyurethanes display enhanced mechanical performance as compared to the petroleum-derived analogues. |
| FILED | Thursday, December 14, 2023 |
| APPL NO | 18/540190 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/44 (20130101) Original (OR) Class C08G 18/0852 (20130101) C08G 18/1875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218144 | Smalyukh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ivan I. Smalyukh (Boulder, Colorado); Andrew Johnston Hess (Louisville, Colorado); Quingkun Liu (Boulder, Colorado); Joshua A. De La Cruz (Denver, Colorado); Blaise Fleury (Boulder, Colorado); Eldho Abraham (Boulder, Colorado); Bohdan Senyuk (Boulder, Colorado); Vladyslav Cherpak (Westminster, Colorado) |
| ABSTRACT | Disclosed are cellulose-based flexible aerogels and xerogels containing bacterial cellulose nanorods, ribbons, fibers, and the like, wherein the gels have tunable optical, heat transfer, and stiffness properties. Further disclosed are highly transparent and flexible cellulose nanofiber-polysiloxane composite aerogels featuring enhanced mechanical robustness, tunable optical anisotropy, and low thermal conductivity. |
| FILED | Tuesday, March 12, 2024 |
| APPL NO | 18/603094 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 9/28 (20130101) Original (OR) Class C08J 2201/026 (20130101) C08J 2201/0504 (20130101) C08J 2205/026 (20130101) C08J 2205/028 (20130101) C08J 2301/02 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/544 (20130101) C08K 7/02 (20130101) C08K 2201/011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218194 | Boley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | John William Boley (Cambridge, Massachusetts); Javier M. Morales Ferrer (Allston, Massachusetts); Stephanie Flores Zopf (Newtonville, Massachusetts); Chloe Grace Kekedjian (Cambridge, Massachusetts); Ramon Enrique Sanchez Cruz (Allston, Massachusetts) |
| ABSTRACT | Methods and compositions for 3D and 4D printing inks exhibit desirable electrical and rheological properties. The compositions disclosed include a 3D printing ink employing a liquid metal emulsion and a method of creating a stretchable electronic device using the same. The compositions also include 4D printing inks and methods of tuning said inks to have desirable properties. |
| FILED | Friday, December 22, 2023 |
| APPL NO | 18/394639 |
| CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/003 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 70/10 (20200101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/36 (20130101) C08K 3/041 (20170501) C08K 3/105 (20180101) C08K 2201/001 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/14 (20130101) C09D 11/023 (20130101) Original (OR) Class C09D 11/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218271 | Timko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Timko (Arlington, Massachusetts); Alex R. Maag (Whitinsville, Massachusetts); Elizabeth Belden (, None); Geoffrey A. Tompsett (Shrewsbury, Massachusetts); Andrew R. Teixeira (Boylston, Massachusetts); Aidin Panahi (Worcester, Massachusetts); Andrew Charlebois (Worcester, Massachusetts); Skyler Kauffman (Worcester, Massachusetts) |
| ABSTRACT | A waste stream of organic matter such as sewage, plant and plastic matter is received for recycling and treated with high temperature and pressure to generate useful organic products such as bio-oil and gas. Byproducts such as char and an aqueous phase including water can be selectively recycled or beingly discarded. An oxidant added to a reactor containing waste from the waste stream facilitates an autothermal reaction under the temperature and pressure applied to the reactor, boosting the temperature slightly from the reactions therein. The reactor generates useful hydrocarbons such as bio-oil resulting from disruption of organic bonds. A combination of oxidation and radical initiation results from the oxidant, and provides an increased yield of bio-oil while decreasing char when compared to temperature and pressure alone. A stoichiometric quantity of the oxidant limits complete conversion of carbon into carbon dioxide by limiting available oxygen and therefore favoring hydrocarbon formation. |
| FILED | Thursday, December 14, 2023 |
| APPL NO | 18/540345 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 11/06 (20130101) Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 53/02 (20130101) C10B 53/07 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 69/06 (20130101) Original (OR) Class C10G 2300/80 (20130101) C10G 2300/1003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240218565 | HOLDEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IMIO TECHNOLOGIES, INC. (Essex Junction, Vermont) |
| ASSIGNEE(S) | IMIO TECHNOLOGIES, INC. (Essex Junction, Vermont) |
| INVENTOR(S) | Victoria I. HOLDEN (Essex Junction, Vermont); Charles Smith (Essex Junction, Vermont) |
| ABSTRACT | Disclosed are microbial compositions having unique combinations of microbial species which are used in plant material recycling and retting. Also disclosed microbial inoculants which contains such a microbial composition, water, and an optional carbon source. The microbial compositions and microbial inoculants are particularly useful in recycling high lignin-content plant material. Methods of making and methods of using the microbial compositions and the microbial inoculants are also described. |
| FILED | Friday, December 15, 2023 |
| APPL NO | 18/542091 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/18 (20130101) C12N 1/20 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/23 (20210501) C12R 2001/24 (20210501) C12R 2001/25 (20210501) C12R 2001/46 (20210501) C12R 2001/86 (20210501) C12R 2001/125 (20210501) C12R 2001/245 (20210501) C12R 2001/465 (20210501) C12R 2001/865 (20210501) C12R 2001/885 (20210501) Chemical Treatment of Natural Filamentary or Fibrous Material to Obtain Filaments or Fibres for Spinning; Carbonising Rags to Recover Animal Fibres D01C 1/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219347 | ZAGHLOUL |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mona E. ZAGHLOUL (Bethesda, Maryland) |
| ABSTRACT | A sensor has a surface acoustic wave (SAW) generator with an input and an output forming a SAW wave therebetween. A 2D material assembly is positioned between the input and output of the SAW generator. The 2D material assembly including a 2D material, whereby the SAW wave increases the sensitivity of the 2D material. A sensor array includes a plurality of sensors, each with a different 2D material. |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/228445 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/022 (20130101) Original (OR) Class G01N 2291/021 (20130101) G01N 2291/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219420 | MITTLEMAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel MITTLEMAN (Providence, Rhode Island); Angela PIZZUTO (Norwich, Connecticut) |
| ABSTRACT | A method for scanning near-field optical microscopy comprises illuminating an apertureless atomic force microscopy (AFM) probe with electromagnetic energy having a frequency in the Terahertz range, where the sample under observation includes a dielectric layer having a thickness greater than the radius of the tip of the AFM probe. A system for scanning near-field optical microscopy comprises a collimated light source for emitting collimated light, a photoconductive antenna for converting collimated light into electromagnetic energy having a frequency in the Terahertz range, an AFM probe, a sample comprising a dielectric layer, the dielectric layer having a thickness greater than the radius of the probe tip; and a detector configured to detect energy that has interacted with the sample. |
| FILED | Thursday, January 04, 2024 |
| APPL NO | 18/404780 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/30 (20130101) Original (OR) Class G01Q 60/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219889 | Young et al. |
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| FUNDED BY |
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| APPLICANT(S) | PASCAL TAGS INC. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brandon Thomas Young (Louisville, Kentucky); James E. Abbott, JR. (Albany, Oregon) |
| ABSTRACT | Systems, apparatus, and methods for fabricating passive identification tags are provided. A method for fabricating a passive identification tag can include: determining a pattern for a resonant structure of a resonance layer of the passive identification tag, and/or determining a pattern for a dielectric structure of a characteristic layer to be disposed on the resonance layer. The method can further include: generating, based on the pattern for the resonant structure, the resonant structure on a substrate to form the resonance layer. The resonant structure generated by the method can respond to an incoming detection signal by transmitting or reflecting a tag response. The method can further include: generating, based on the pattern for the dielectric structure, the dielectric structure on the resonance layer to form the characteristic layer. The dielectric structure can modify the tag response, so that a modified tag response is transmitted or reflected to a receiver. |
| FILED | Saturday, April 30, 2022 |
| APPL NO | 18/288974 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) Original (OR) Class G05B 2219/49023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240220746 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pascal Tags Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brandon Thomas Young (Louisville, Kentucky); Robrt Rudolf Rotzoll (Cascade, Colorado) |
| ABSTRACT | System, device, and method for detecting a passive identification tag and identifying a tag ID for the passive identification tag are provided. The system can include a transmitting system, a passive identification tag, and a receiving system. The transmitting system generates one or more detection signals to interrogate the passive identification tag, where the one or more detection signals includes a first detection signal having a first frequency range. The passive identification tag receives the one or more detection signals, and generates at least a first tag response in response to the first detection signal. The receiving system receives the first tag response, and processes the first tag response to determine a plurality of signal components for the first frequency range, where the plurality of signal components can be used to determine the tag ID. |
| FILED | Saturday, April 30, 2022 |
| APPL NO | 18/288969 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10366 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240220839 | Levonian et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David S. Levonian (Cambridge, Massachusetts); Ralf RIEDINGER (Cambridge, Massachusetts); Bartholomeus MACHIELSE (Cambridge, Massachusetts); Mihir Keshav BHASKAR (Cambridge, Massachusetts); Mikhail D. LUKIN (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods are disclosed for optically entangling distinguishable qubits. A system can include a first qubit having an optical transition at a first qubit frequency, a second qubit having an optical transition at a second qubit frequency, and a light source producing a first light beam having at least a first frequency. An interferometer can be configured to convert the first light beam into at least one second light beam, to provide the at least one second light beam to the first qubit and the second qubit, and to provide an output light signal. The interferometer can include a first optical modulator that converts the first light beam into the at least one second light beam, and a second optical modulator that produces the output light signal from the at least one second light beam. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 18/557493 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240220840 | JACOB et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Ajey Poovannummoottil JACOB (Los Angeles, California); Akhilesh Ramlaut JAISWAL (Los Angeles, California); Ramesh KUDALIPPALLIYALIL (Los Angeles, California) |
| ABSTRACT | A heterogeneous quantum device includes an interposer, a qubit sources disposed over the interposer, and an electro-optic quantum transducer disposed over the interposer. The electro-optic quantum transducer being a frequency converter that converts microwave frequency to optical frequency coupled to the qubit sources by superconducting capacitive or inductive coupling. |
| FILED | Tuesday, August 16, 2022 |
| APPL NO | 18/684145 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240220888 | Sherafat et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Behnam Sherafat (Salt Lake City, Utah); Abbas Rashidi (Salt Lake City, Utah); Armin Tajalli (Salt Lake City, Utah) |
| ABSTRACT | Disclosed systems and methods create a schedule by a scheduling software. The scheduling software receives a project or certain activities that includes information that describes requirements of the project or certain activities. The scheduling software also receives a dataset of available heavy equipment associated with the project or certain activities and selects a set of heavy equipment from the dataset of available heavy equipment. Each heavy equipment includes at least one sensor and sensor data is received from the sensor(s) for each heavy equipment. The scheduling software maps the sensor data to a profile. The profile characterizes a machine learning algorithm for at least one heavy equipment selected from the set of heavy equipment and outputs a set of productivity rates for at least a portion of the set of heavy equipment. The scheduling software automatically updates the schedule based on the set of productivity rates. |
| FILED | Wednesday, September 27, 2023 |
| APPL NO | 18/475627 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06312 (20130101) Original (OR) Class G06Q 50/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240222036 | Ng et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tse Nga Ng (San Diego, California); Lulu Yao (Fremont, California) |
| ABSTRACT | Embodiments of the presently disclosed technology provide improved structural supercapacitors that increase multi-functional efficiency (i.e., improve energy-storage and mechanical load-bearing capacity/performance). Structural supercapacitors of the present technology achieve such improvements in part by focusing on interfaces between structural electrodes and structural electrolytes. For example, the present technology can provide improved structural electrodes by coating carbon fiber-based structures with a uniquely stable conjugated redox polymer and a carbon-based compound. Such coating (at the interface between the structural electrode and a structural electrolyte) can improve and tensile strength for the structural electrode. The present technology can also provide improved structural electrolytes that leverage a “gradient” configuration for a structural electrolyte where composition of the structural electrolyte is tuned such that regions of the structural electrolyte immediately adjacent to structural electrodes incorporate a higher concentration of an ion-conducting polymer and salt than “middle” regions of the structural electrolyte. |
| FILED | Wednesday, December 20, 2023 |
| APPL NO | 18/391126 |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/32 (20130101) Original (OR) Class H01G 11/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240222652 | Kumta et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prashant N. Kumta (Pittsburgh, Pennsylvania); Shrinath Dattatray Ghadge (Pittsburgh, Pennsylvania); Oleg Velikokhatnyi (Pittsburgh, Pennsylvania); Moni Kanchan Datta (Pittsburgh, Pennsylvania) |
| ABSTRACT | The invention relates to systems and methods for successful operation of acid mediated proton exchange membrane fuel cell (PEMFC), and highly efficient, earth-abundant, and ultra-low noble metal-containing, e.g., platinum group metal (PGM)-containing, electrocatalyst materials for anodic hydrogen oxidation reaction (HOR). The electrocatalyst materials include metal silicide alloy-based solid solutions of the general formula: (A(n-x)Bx)Siy, wherein A is a transition metal element or mixture or alloy thereof, B is a noble metal element or mixture or alloy thereof, and each of n and x, is a positive integer or a positive fractional number, and y is a positive integer. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/550084 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/06 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/50 (20130101) C01P 2002/72 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/921 (20130101) Original (OR) Class H01M 4/923 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240223106 | Preindl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (, None) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthias Preindl (New York, New York); Liwei Zhou (New York, New York); William-Michael Eull (Oakville, Ontario, Canada); Matthew Jahnes (New York, New York) |
| ABSTRACT | Disclosed are implementations that include a non-isolated power converter system comprising a filter including an inductor and a capacitor. The inductor of the filter includes a core portion and a winding portion. The core portion may include different shape core structures. The winding portion includes a winding embedded within a printed circuit board. The printed circuit board winding may include a litz wiring, and the printed circuit board having located thereon one or more of a controller or power switching elements. |
| FILED | Wednesday, July 27, 2022 |
| APPL NO | 18/292317 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/44 (20130101) H02M 1/0058 (20210501) H02M 7/81 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20240218352 | Shoura et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Massa Shoura (Stanford, California); Stephen Levene (Redwood City, California); David Girata (Redwood City, California) |
| ABSTRACT | Methods are provided for the isolation and analysis of circular DNA from complex samples, based on the topology of the DNA molecule. A sample comprising DNA species is combined with a chaotropic dense salt solution. A fraction containing the circular DNA of interest is isolated and dialyzed to remove excess salt. In some embodiments salt gradients are generated by ultracentrifugation in the absence of intercalating dyes, e.g. ethidium bromide; and in the absence of protease digestion. The circular DNA thus isolated is substantially pure, e.g. greater than about 75%, greater than about 80%, greater than about 90%, greater than about 95% of DNA in the isolated fraction is comprised of circular DNA. |
| FILED | Thursday, March 07, 2024 |
| APPL NO | 18/598993 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1003 (20130101) C12N 15/1006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240220835 | Gorshkov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexey Vyacheslavovich Gorshkov (Potomac, Maryland); Adam Ethan Ehrenberg (University Park, Maryland); Jacob Allen Bringewatt (Hyattsville, Maryland) |
| ABSTRACT | Measuring a single linear function q(θ1, θ2, . . . , θd) of unknown parameters {θ1, θ2, . . . , θd} with a quantum sensor network while using the minimum amount of entanglement includes: providing a plurality of d quantum sensors, wherein each quantum sensor j is configured for measuring θj; preparing the plurality of quantum sensors in a probe quantum state with a minimum amount of entanglement, such that the amount of entanglement is the smallest amount of entanglement that gives the same optimal measurement of the linear function q(θ1, θ2, . . . , θd) as if the amount of entanglement was not restricted; exposing the plurality of quantum sensors to the set of unknown parameters; measuring the plurality of quantum sensors; and calculating the single linear function q(θ1, θ2, . . . , θd) from the measurements of the plurality of quantum sensors with robust phase estimation. |
| FILED | Friday, August 11, 2023 |
| APPL NO | 18/232890 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) Original (OR) Class G06N 10/70 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20240216068 | Gooding et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Rachel Gooding (Herndon, Virginia); Alexander Dolan (Frederick, Maryland); David Bradley (Bel Air, Maryland); Kevin Wegman (Columbus, Ohio); Patrick Wilson (Dublin, Ohio); Brian Hawkins (Broomfield, Colorado); Timothy Davis (Atlanta, Georgia); Thomas Kirsch (Bethesda, Maryland) |
| ABSTRACT | A system to estimate consequences of an explosion includes a scenario generator to generate a scenario based on user input and scenario parameters; an explosive device model generator to generate an explosive device model based on the user input and explosive device parameters; a propagation of hazards modeler to model propagation of hazards into the scenario based on the user input and hazard parameters; an injury modeler to model injuries corresponding to modeling propagation of hazards into the scenario based on injury parameters; and an iteration and output generator to iterate by using additional iterative subsets of the parameters to generate the scenario, generate the explosive device model, model propagation of hazards, and model injuries, until parameter spaces of the parameters are covered. The iteration and output generator generates an injury record based injury outcomes from the modeling of injuries corresponding to the iterating. |
| FILED | Monday, August 14, 2023 |
| APPL NO | 18/233738 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 2034/105 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240219307 | CLINTON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
| ASSIGNEE(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
| INVENTOR(S) | Charles M. CLINTON (Clarksburg, Maryland); Eli N. GLEZER (Chevy Chase, Maryland); Sharon WEST (Rockville, Maryland); George SIGAL (Rockville, Maryland); Carl STEVENS (Silver Spring, Maryland); Michael L. VOCK (Loveland, Ohio) |
| ABSTRACT | We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring. |
| FILED | Wednesday, January 31, 2024 |
| APPL NO | 18/429280 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/69 (20130101) G01N 21/76 (20130101) Original (OR) Class G01N 35/028 (20130101) G01N 35/0092 (20130101) G01N 35/1079 (20130101) G01N 2035/0425 (20130101) G01N 2035/00524 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/114165 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20240217430 | Massa |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HiViz LED Lighting, Inc. (Hendersonville, North Carolina) |
| ASSIGNEE(S) | HiViz LED Lighting, Inc. (Hendersonville, North Carolina) |
| INVENTOR(S) | Samuel T. Massa (Hendersonville, North Carolina) |
| ABSTRACT | A lighting system configured to be coupled to a vehicle, the lighting system including a light source configured to illuminate a target area in front of the vehicle from above, wherein the lighting system is configured to move between a retracted position and an extended position. Further, A method of preventing accidents, including positioning a light source above a target area by extending a light structure to an extended position outward from a vehicle, turning off headlights of the vehicle, and illuminating the target area from above with the light source. |
| FILED | Wednesday, January 03, 2024 |
| APPL NO | 18/403315 |
| CURRENT CPC | Arrangement of Signalling or Lighting Devices, the Mounting or Supporting Thereof or Circuits Therefor, for Vehicles in General B60Q 1/525 (20130101) B60Q 1/1423 (20130101) B60Q 1/2611 (20130101) B60Q 1/2615 (20130101) B60Q 1/2692 (20130101) Original (OR) Class B60Q 1/2696 (20130101) B60Q 2300/45 (20130101) B60Q 2800/30 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240217668 | Strutt |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rohr, Inc. (Chula Vista, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew J. Strutt (San Diego, California) |
| ABSTRACT | An exhaust center body includes an inner skin, a perforated outer skin, a first bulkhead, a second bulkhead, a baffle and an acoustic chamber. The first bulkhead extends radially between the inner skin and the perforated outer skin. The second bulkhead extends radially between the inner skin and the perforated outer skin. The baffle includes a panel and a flange formed integral with the panel. The panel extends radially between the inner skin and the perforated outer skin. The panel extends axially along the axial centerline between the first bulkhead and the second bulkhead. The panel is attached to one of the inner skin, the first bulkhead or the second bulkhead by the flange. The acoustic chamber is formed radially between the inner skin and the perforated outer skin, axially between the first bulkhead and the second bulkhead, and circumferentially adjacent the baffle. |
| FILED | Wednesday, January 03, 2024 |
| APPL NO | 18/403310 |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/06 (20130101) Original (OR) Class Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240222690 | Dornbusch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donald A. Dornbusch (Cleveland, Ohio); Rocco P. Viggiano (Cleveland, Ohio); Amjad S. Almansour (Cleveland, Ohio); Yi Lin (Cleveland, Ohio) |
| ABSTRACT | According to some embodiments described and disclosed herein, a separator may comprise a filler and an inorganic solid electrolyte. The filler may comprise fibers with an aspect ratio (L/D) of at least 100/1. The separator may have a thickness of less than 200 μm. Further embodiments include a process for producing a separator. |
| FILED | Friday, December 15, 2023 |
| APPL NO | 18/542107 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/056 (20130101) Original (OR) Class H01M 2300/008 (20130101) H01M 2300/0082 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240222691 | HU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Liangbing HU (Hyattsville, Maryland); Eric Wachsman (Fulton, Maryland); Chengwei Wang (College Park, Maryland); Yunhui Gong (Clarksville, Maryland) |
| ABSTRACT | The present invention is directed to solid state electrolytes that comprise a coating layer. The present invention is also directed to methods of making the solid state electrolyte materials and methods of using the solid state electrolyte materials in batteries and other electrochemical technologies. |
| FILED | Thursday, July 20, 2023 |
| APPL NO | 18/224284 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 33/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0077 (20130101) H01M 2300/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20240219951 | MONROE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher MONROE (Ellicott City, Maryland); Jiehang ZHANG (College Park, Maryland); David WONG-CAMPOS (Hyattsville, Maryland); Antonios KYPRIANIDIS (Takoma, Maryland); Patrick Michael BECKER (College Park, Maryland) |
| ABSTRACT | The disclosure describes an adaptive and optimal imaging of individual quantum emitters within a lattice or optical field of view for quantum computing. Advanced image processing techniques are described to identify individual optically active quantum bits (qubits) with an imager. Images of individual and optically-resolved quantum emitters fluorescing as a lattice are decomposed and recognized based on fluorescence. Expected spatial distributions of the quantum emitters guides the processing, which uses adaptive fitting of peak distribution functions to determine the number of quantum emitters in real time. These techniques can be used for the loading process, where atoms or ions enter the trap one-by-one, for the identification of solid-state emitters, and for internal state-detection of the quantum emitters, where each emitter can be fluorescent or dark depending on its internal state. This latter application is relevant to efficient and fast detection of optically active qubits in quantum simulations and quantum computing. |
| FILED | Friday, April 28, 2023 |
| APPL NO | 18/309559 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) G01J 2001/4247 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Computing Devices; G06E 3/005 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/66977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240223697 | BALASUBRAMANIYAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| INVENTOR(S) | Vijay BALASUBRAMANIYAN (Atlanta, Georgia); Mustaque AHAMAD (Atlanta, Georgia); Patrick Traynor (Decatur, Georgia); Michael Thomas HUNTER (Atlanta, Georgia); Aamir POONAWALLA (Atlanta, Georgia) |
| ABSTRACT | Various embodiments of the invention are detection systems and methods for detecting call provenance based on call audio. An exemplary embodiment of the detection system can comprise a characterization unit, a labeling unit, and an identification unit. The characterization unit can extract various characteristics of networks through which a call traversed, based on call audio. The labeling unit can be trained on prior call data and can identify one or more codecs used to encode the call, based on the call audio. The identification unit can utilize the characteristics of traversed networks and the identified codecs, and based on this information, the identification unit can provide a provenance fingerprint for the call. Based on the call provenance fingerprint, the detection system can identify, verify, or provide forensic information about a call audio source. |
| FILED | Thursday, February 08, 2024 |
| APPL NO | 18/436668 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0829 (20130101) H04L 65/1076 (20130101) Telephonic Communication H04M 1/68 (20130101) H04M 3/2281 (20130101) Original (OR) Class H04M 7/0078 (20130101) H04M 2203/558 (20130101) H04M 2203/6027 (20130101) H04M 2203/6045 (20130101) Wireless Communication Networks H04W 12/02 (20130101) H04W 12/12 (20130101) H04W 12/63 (20210101) H04W 12/65 (20210101) H04W 24/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20240219951 | MONROE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher MONROE (Ellicott City, Maryland); Jiehang ZHANG (College Park, Maryland); David WONG-CAMPOS (Hyattsville, Maryland); Antonios KYPRIANIDIS (Takoma, Maryland); Patrick Michael BECKER (College Park, Maryland) |
| ABSTRACT | The disclosure describes an adaptive and optimal imaging of individual quantum emitters within a lattice or optical field of view for quantum computing. Advanced image processing techniques are described to identify individual optically active quantum bits (qubits) with an imager. Images of individual and optically-resolved quantum emitters fluorescing as a lattice are decomposed and recognized based on fluorescence. Expected spatial distributions of the quantum emitters guides the processing, which uses adaptive fitting of peak distribution functions to determine the number of quantum emitters in real time. These techniques can be used for the loading process, where atoms or ions enter the trap one-by-one, for the identification of solid-state emitters, and for internal state-detection of the quantum emitters, where each emitter can be fluorescent or dark depending on its internal state. This latter application is relevant to efficient and fast detection of optically active qubits in quantum simulations and quantum computing. |
| FILED | Friday, April 28, 2023 |
| APPL NO | 18/309559 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) G01J 2001/4247 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Computing Devices; G06E 3/005 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/66977 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240220835 | Gorshkov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexey Vyacheslavovich Gorshkov (Potomac, Maryland); Adam Ethan Ehrenberg (University Park, Maryland); Jacob Allen Bringewatt (Hyattsville, Maryland) |
| ABSTRACT | Measuring a single linear function q(θ1, θ2, . . . , θd) of unknown parameters {θ1, θ2, . . . , θd} with a quantum sensor network while using the minimum amount of entanglement includes: providing a plurality of d quantum sensors, wherein each quantum sensor j is configured for measuring θj; preparing the plurality of quantum sensors in a probe quantum state with a minimum amount of entanglement, such that the amount of entanglement is the smallest amount of entanglement that gives the same optimal measurement of the linear function q(θ1, θ2, . . . , θd) as if the amount of entanglement was not restricted; exposing the plurality of quantum sensors to the set of unknown parameters; measuring the plurality of quantum sensors; and calculating the single linear function q(θ1, θ2, . . . , θd) from the measurements of the plurality of quantum sensors with robust phase estimation. |
| FILED | Friday, August 11, 2023 |
| APPL NO | 18/232890 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) Original (OR) Class G06N 10/70 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20240220925 | Bolha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rosemarie Bolha (Wilkes-Barre, Pennsylvania); Stephen M. Dearing (Herndon, Virginia) |
| ABSTRACT | Systems and methods for tracking items. A system for tracking an item is configured to scan the item for a computer readable code and convert the computer readable code into a digital identifier associated with the item. The system includes a controller circuit configured to receive authentication information from the mobile computing device, receive a request from the mobile computing device, comprising the digital identifier and a request for information relating to the item. When the memory has the information, the controller circuit obtains the information from the memory and generates an output comprising the digital identifier and the information for display. The output is based on a comparison of a location of the mobile computing device and an expected location of the item. |
| FILED | Monday, March 11, 2024 |
| APPL NO | 18/601220 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/087 (20130101) Original (OR) Class G06Q 10/0833 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) Wireless Communication Networks H04W 12/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240221541 | BONNELL |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clayton C. BONNELL (Fairfax, Virginia) |
| ABSTRACT | A method is provided for tracking and/or locating a delivery item transport equipment label. A delivery-item transport equipment label is scanned. At least one of a first identifier that is attached to a bracket or an RFID chip that is attached to the bracket is scanned to associate the delivery-item transport equipment label with the RFID chip. The RFID chip is scanned during use of a delivery-item transport equipment to which the bracket is attached. A location of the delivery-item transport equipment label is identified based on the scanning of the RFID chip. |
| FILED | Tuesday, March 12, 2024 |
| APPL NO | 18/602763 |
| CURRENT CPC | Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 13/02 (20130101) Displaying; Advertising; Signs; Labels or Name-plates; Seals G09F 7/18 (20130101) Original (OR) Class G09F 21/00 (20130101) G09F 2007/1847 (20130101) G09F 2007/1856 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20240215590 | Yoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Antithesis Foods Inc. (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Antithesis Foods Inc. (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Ashton Yoon (Philadelphia, Pennsylvania); Jason Goodman (Philadelphia, Pennsylvania); Alexandra Hall (Philadelphia, Pennsylvania) |
| ABSTRACT | A system and method for the production of doughs and products using textured pulse proteins, including legume-based crunchy snack foods, said method comprising the steps of: homogenization of ingredients in the form of dry feed powders, mixing and hydration of powders with liquid ingredients to form a dough, forming of the dough into form factors, drying and expansion of the form factors to develop texture and shelf stability, and cooling. |
| FILED | Monday, March 18, 2024 |
| APPL NO | 18/608783 |
| CURRENT CPC | Treatment, e.g Preservation, of Flour or Dough, e.g by Addition of Materials; Baking; Bakery Products; Preservation Thereof A21D 2/266 (20130101) Original (OR) Class A21D 2/362 (20130101) A21D 8/02 (20130101) A21D 10/002 (20130101) A21D 13/06 (20130101) A21D 13/045 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20240216410 | JENQ et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Robert R. JENQ (Houston, Texas); Mohamed A. JAMAL (Houston, Texas); Jennifer L. KARMOUCH (Houston, Texas); Eiko HAYASE (Houston, Texas) |
| ABSTRACT | The current disclosure provides methods and compositions related to treating or preventing neutropenic fever (e.g., cancer therapy-induced neutropenic fever) and/or GVHD (e.g., HCT-related and/or neutropenic fever therapy-induced GVHD). In specific cases, it may be determined whether or not the subject is likely to develop or is at risk of developing neutropenic fever and/or GVHD, such as cancer therapy-induced neutropenic fever and/or HCT-related and/or neutropenic fever therapy-induced GVHD, based on the subject's gut microbiome. A subject may be provided a composition comprising one or more agents targeting growth or expansion the one or more genera of mucus-degrading gut bacteria, one or more mucus-degrading enzyme inhibitors, one or more mediators of organic acid metabolite levels, and/or one or more carbohydrate substrates metabolized by the one or more genera of mucus-degrading gut bacteria based on analysis of the gut microbiome of the subject receiving a HCT therapy and/or a neutropenic fever therapy following administration of a cancer therapy, in specific embodiments. |
| FILED | Thursday, March 24, 2022 |
| APPL NO | 18/283408 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/12 (20130101) A61K 31/19 (20130101) A61K 31/407 (20130101) A61K 31/546 (20130101) A61K 31/714 (20130101) A61K 31/4045 (20130101) A61K 31/7004 (20130101) A61K 31/7052 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, July 04, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240704.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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