FedInvent™ Patent Applications
Application Details for Thursday, August 01, 2024
This page was updated on Friday, August 02, 2024 at 04:19 PM GMT
Department of Health and Human Services (HHS)
| US 20240252053 | Zhou et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Wenjun Zhou (Davis, California); Oybek Kholiqov (Davis, California); Vivek Jay Srinivasan (Davis, California) |
| ABSTRACT | The disclosed embodiments provide a system that non-invasively analyzes blood flow in a sample of living tissue. During operation, the system obtains light from a temporally coherent source, and splits the obtained light between a reference path and a sample path. Next, the system multiply scatters light from the sample path by passing the light through the sample. The system then recombines light from the reference path and the multiply scattered light from the sample path. Next, the system uses a sensor array to detect an interference pattern resulting from the recombination. Finally, the system analyzes signals from the sensor array to determine a blood flow in the sample. |
| FILED | Tuesday, April 09, 2024 |
| APPL NO | 18/630334 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0261 (20130101) Original (OR) Class A61B 5/4064 (20130101) A61B 2562/04 (20130101) A61B 2562/0238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252087 | Mendenhall et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); UPMC (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); UPMC (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | George Stuart Mendenhall (Pittsburgh, Pennsylvania); Matthew Jones (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed are wearable bands, such as rings, for monitoring and diagnosing cardiovascular conditions of a wearer, along with related systems, algorithms, and methods. The disclosed wearable bands can continuously monitor the wearer's cardiovascular status by measuring heart rate and/or other physiological properties of the wearer. Disclosed wearable bands can further comprise at least two EKG electrodes, including a first electrode on the inner surface adapted to detect a signal from the finger and a second electrode on the outer surface adapted to detect a cardiovascular signal from another body part. The wearable bands can be linked wirelessly to a mobile device that the person can interact with. The mobile device can be linked to other distributed system components and healthcare providers, such as to send a message to a predetermined recipient based upon the physiological properties measured by the wearable band. |
| FILED | Friday, April 12, 2024 |
| APPL NO | 18/634133 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/11 (20130101) A61B 5/0022 (20130101) A61B 5/25 (20210101) Original (OR) Class A61B 5/0205 (20130101) A61B 5/349 (20210101) A61B 5/389 (20210101) A61B 5/683 (20130101) A61B 5/02438 (20130101) A61B 5/6826 (20130101) A61B 5/7275 (20130101) A61B 5/14552 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/048 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252089 | Dudek et al. |
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| FUNDED BY |
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| APPLICANT(S) | Epitel, Inc. (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Francis E. Dudek (Salt Lake City, Utah); Michael K. Elwood (Farmington, Utah); John H. Fisher (Cottonwood Heights, Utah); Mark J. Lehmkuhle (Salt Lake City, Utah); Jean M. Wheeler (Salt Lake City, Utah) |
| ABSTRACT | Disclosed systems, methods, and products include a self-contained electroencephalogram (EEG) recording patch including a first electrode, a second electrode and where the first and second electrodes cooperate to measure a skin-electrode signal, a substrate containing circuitry for generating an EEG signal there-from, amplifying the EEG signal, digitizing the EEG signal, and retrievably storing the EGG signal in a programmatic fashion. The patch also comprises a power source and an enclosure that houses the substrate, the power source, and the first and second electrodes in a unitary package. |
| FILED | Thursday, February 01, 2024 |
| APPL NO | 18/430125 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/291 (20210101) Original (OR) Class A61B 5/316 (20210101) A61B 5/369 (20210101) A61B 5/742 (20130101) A61B 5/746 (20130101) A61B 5/4094 (20130101) A61B 5/6814 (20130101) A61B 5/6833 (20130101) A61B 17/3468 (20130101) A61B 2560/0209 (20130101) A61B 2560/0412 (20130101) A61B 2560/0431 (20130101) A61B 2562/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252096 | GROVER et al. |
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| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | PULKIT GROVER (Pittsburgh, Pennsylvania); ALIREZA CHAMANZAR (Pittsburgh, Pennsylvania); MARLENE BEHRMANN COHEN (Pittsburgh, Pennsylvania) |
| ABSTRACT | A novel method for using the widely-used electroencephalography (EEG) systems to detect and localize silences in the brain is disclosed. The method detects the absence of electrophysiological signals, or neural silences, using noninvasive scalp electroencephalography (EEG) signals. This method can also be used for reduced activity localization, activity level mapping throughout the brain, as well as mapping activity levels in different frequency bands. By accounting for the contributions of different sources to the power of the recorded signals and using a hemispheric baseline approach and a convex spectral clustering framework, the method permits rapid detection and localization of regions of silence in the brain using a relatively small amount of EEG data. |
| FILED | Thursday, January 11, 2024 |
| APPL NO | 18/410446 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/372 (20210101) Original (OR) Class A61B 5/7264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252099 | FAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Xudong FAN (Saline, Michigan); Anjali Devi SIVAKUMAR (Ann Arbor, Michigan) |
| ABSTRACT | Transepidermal water loss (TEWL) measurement approach is presented that achieves accurate and continuous monitoring completely independent of ambient environmental variations. This new measurement approach uses short dry air purges to dry the skin surface and the water vapor collection chamber, thus refreshing the measurement site each time during skin barrier analysis. These dry air purges help maintain a highly controlled localized measuring environment without disturbing any inherent skin properties, enabling one to produce reproducible TEWL results. A mathematical model developed based on Fick's laws of diffusion is presented, and shown to have excellent agreement with the mathematical model of a commercial TEWL device. The application of this mathematical model in deciphering the TEWL values from the transient microclimate behavior in the vapor measuring chamber of the new TEWL approach is also discussed. |
| FILED | Wednesday, January 31, 2024 |
| APPL NO | 18/428514 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/681 (20130101) A61B 5/4266 (20130101) Original (OR) Class A61B 2560/0252 (20130101) A61B 2562/029 (20130101) Separation B01D 53/02 (20130101) B01D 53/266 (20130101) B01D 2257/80 (20130101) B01D 2257/702 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252102 | YEO et al. |
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| FUNDED BY |
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| APPLICANT(S) | Woon-Hong YEO (Atlanta, Georgia); Hyojung J. CHOO (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); EMORY UNIVERSITY (Atlanta, Georgia) |
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| INVENTOR(S) | Woon-Hong YEO (Atlanta, Georgia); Hyojung J. CHOO (Atlanta, Georgia) |
| ABSTRACT | Described herein are wireless nanomembrane non-invasive system that integrates skin-wearable printed sensors and electronics and methods that can be used to monitor an electrophysiological parameter of a subject or to identify a therapeutic agent. The systems can include wearable devices, including skin-wearable printed sensors; and electronics for real-time, continuous monitoring of electrophysiological parameters of a subject. |
| FILED | Friday, May 27, 2022 |
| APPL NO | 18/564391 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/28 (20210101) A61B 5/257 (20210101) A61B 5/291 (20210101) A61B 5/296 (20210101) A61B 5/4519 (20130101) Original (OR) Class A61B 5/4842 (20130101) A61B 5/4848 (20130101) A61B 5/6832 (20130101) A61B 2503/40 (20130101) A61B 2503/42 (20130101) A61B 2560/0468 (20130101) A61B 2562/028 (20130101) A61B 2562/125 (20130101) A61B 2562/164 (20130101) A61B 2562/166 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252389 | Mghari et al. |
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| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Hassan El Mghari (Philadelphia, Pennsylvania); Gregory Olsen (Landsdale, Pennsylvania); Zikang Ling (Philadelphia, Pennsylvania); Srivatsa Rayar Ganesh (Garnet Valley, Pennsylvania); William Mongan (Coatesville, Pennsylvania); Vasil Pano (Portland, Oregon); Kapil R. Dandekar (Philadelphia, Pennsylvania) |
| ABSTRACT | A deep vein thrombosis prevention device (DVT-PD) is a wearable device for the lower extremities senses the user's dynamic or static movements and actuates accordingly to lower DVT risks. The device uses a comprehensive control system together with an integrated machine learning model. to classify, manage, direct, and regulate signals and the behavior of the device. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 18/560487 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 9/0078 (20130101) A61H 15/0078 (20130101) Original (OR) Class A61H 2201/10 (20130101) A61H 2201/123 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/501 (20130101) A61H 2201/1654 (20130101) A61H 2201/5084 (20130101) A61H 2209/00 (20130101) A61H 2230/085 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0452 (20130101) A61N 1/36031 (20170801) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252438 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
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| INVENTOR(S) | Liangfang Zhang (San Diego, California); Che-Ming (Jack) Hu (San Diego, California); Ronnie Hongbo Fang (Irvine, California); Jonathan Copp (La Jolla, California) |
| ABSTRACT | Provided are nanoparticles and methods of using and making thereof. The inventive nanoparticle comprises a) an inner core comprising a non-cellular material; and b) an outer surface comprising a cellular membrane derived from a cell or a membrane derived from a virus. Medicament delivery systems or pharmaceutical compositions comprising the inventive nanoparticles are also provided. Further provided are immunogenic compositions comprising the inventive nanoparticles, and methods of using the inventive immunogenic compositions for eliciting an immune response, and for treating or preventing diseases or condition, such as neoplasm or cancer, or disease or conditions associated with cell membrane inserting toxin. Vaccines comprising the immunogenic composition comprising the nanoparticles are also provided. |
| FILED | Tuesday, February 20, 2024 |
| APPL NO | 18/582123 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/148 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 39/085 (20130101) A61K 39/001102 (20180801) A61K 45/06 (20130101) A61K 2039/80 (20180801) A61K 2039/55555 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252483 | BHISE et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lyndra Therapeutics, Inc. (Watertown, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nupura BHISE (Watertown, Massachusetts); Jeffrey KATSTRA (Watertown, Massachusetts); David ALTREUTER (Watertown, Massachusetts) |
| ABSTRACT | Provided are gastric residence systems comprising at least one co-extruded drug-eluting component comprising a carrier polymer, buprenorphine or a salt thereof, and naloxone or a salt thereof, and a rate-modulating release film coating the at least one co-extruded drug-eluting component. The gastric residence systems comprising at least one co-extruded drug-eluting component are configured to be maintained within a stomach of a human body for at least 48 hours and to release buprenorphine for at least 48 hours, such that the at least one co-extruded drug eluting component with the rate-modulating release film is configured to release at least 10% of the buprenorphine or the salt thereof after the first 24 hours of residence within the stomach and at least 10% of the naloxone or the salt thereof after the first 24 hours of residence within the stomach. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 18/289331 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/0019 (20130101) A61K 9/0065 (20130101) A61K 9/146 (20130101) A61K 31/485 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252494 | Gurtner et al. |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Standford, California) |
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| INVENTOR(S) | Geoffrey Gurtner (Stanford, California); Kellen Chen (Stanford, California); Dominic Henn (Stanford, California) |
| ABSTRACT | Skin graft methods are provided. Aspects of the methods include applying a skin graft to a wound in combination with a mechanotransduction blocker, such as a pharmacological mechanotransduction blocker, e.g., a focal adhesion kinase inhibitor. Also provided are compositions and kits for use practicing methods of the invention. |
| FILED | Monday, July 25, 2022 |
| APPL NO | 18/288652 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/322 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/008 (20130101) A61L 26/0023 (20130101) A61L 26/0066 (20130101) A61L 27/60 (20130101) A61L 27/362 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252496 | Ozcan et al. |
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| APPLICANT(S) | The Children’s Medical Center Corporation (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
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| INVENTOR(S) | Umut Ozcan (Weston, Massachusetts); Ralph Mazitschek (Weston, Massachusetts); Dongxian Guan (Brighton, Massachusetts) |
| ABSTRACT | Formulations of HDAC6 inhibitors passing through the blood brain barrier in hypothalamus and inhibiting HDAC6 in the arctuate AgRP neurons in the hypothalamus, are effective to cause weight loss in obese individuals. These inhibitors also restore leptin sensitivity in leptin-resistant individuals. |
| FILED | Monday, February 12, 2024 |
| APPL NO | 18/439517 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252541 | WOODS et al. |
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| APPLICANT(S) | Ossium Health, Inc. (San Francisco, California); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik J. WOODS (Carmel, Indiana); Brian H. JOHNSTONE (Fishers, Indiana); Dongsheng GU (Indianapolis, Indiana); Aubrey Marie SHERRY (Carmel, Indiana); Kelsey Gwen MUSALL (Avon, Indiana); Kazuhiko YAMADA (New York, New York); Megan SYKES (New York, New York) |
| ABSTRACT | Described herein are methods of cell therapies. Also described herein are methods of establishing a mixed chimerism, and/or preventing a rejection of a donor organ in a subject wherein said subject has received an organ transplant, the method comprising administering to said subject a population of hematopoietic cells, wherein said organ transplant comprises a heart transplant. |
| FILED | Monday, July 24, 2023 |
| APPL NO | 18/357976 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 35/28 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Peptides C07K 16/26 (20130101) C07K 16/2806 (20130101) C07K 16/2875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252552 | Thumbikat |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
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| INVENTOR(S) | Praveen Thumbikat (Evanston, Illinois) |
| ABSTRACT | Disclosed herein are compositions comprising lipoteichoic acid (LTA) and the use thereof for modulating neuronal activity. The disclosed LTA compositions may be prepared using LTA that is derived from the Gram positive bacteria Staphylococcus epidermidis. The disclosed LTA compositions may be administered to treat pain, including but not limited to chronic pelvic pain syndrome (CPPS), neurogenic pain, or neurogenic inflammation via PD-1 inhibitory signaling in neurons. The disclosed LTA compositions may be administered in order to modulate the expression of endogenous opioids. |
| FILED | Monday, January 22, 2024 |
| APPL NO | 18/418897 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7032 (20130101) A61K 35/74 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252558 | Claud et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
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| INVENTOR(S) | Erika C. Claud (Chicago, Illinois); Jing Lu (Chicago, Illinois); Lei Lu (Chicago, Illinois) |
| ABSTRACT | Provided herein are probiotics and methods of use thereof for treating one or more neurodevelopmental deficits in a subject resulting from exposure of the subject to maternal immune activation. |
| FILED | Monday, January 29, 2024 |
| APPL NO | 18/425731 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/747 (20130101) Original (OR) Class A61K 2035/115 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252586 | STECKBECK et al. |
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| APPLICANT(S) | Peptilogics, Inc. (Pittsburgh, Pennsylvania) |
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| INVENTOR(S) | Jonathan D. STECKBECK (Pittsburgh, Pennsylvania); Bradd N. PICONE (Pittsburgh, Pennsylvania); Despina X. DOBBINS (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided in this disclosure are pharmaceutical formulations comprising antimicrobial peptides with a basic pH. Further provided herein are methods of treating or preventing an infection comprising administering pharmaceutical formulations comprising antimicrobial peptides when administered to a subject. |
| FILED | Friday, March 15, 2024 |
| APPL NO | 18/606023 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/162 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252593 | CAMILLERI et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael L. CAMILLERI (Rochester, Minnesota); Andres J. ACOSTA (Rochester, Minnesota); Paul A. DECKER (Rochester, Minnesota); Jeanette E. ECKEL PASSOW (Pine Island, Minnesota) |
| ABSTRACT | The present disclosure relates to methods and materials for assessing and/or treating obesity and/or obesity-related co-morbidities in mammals (e.g., humans). For example, methods and materials for using one or more interventions (e.g., one or more pharmacological interventions) to treat obesity and/or obesity-related co-morbidities in a mammal (e.g., a human) identified as being likely to respond to a particular intervention (e.g., a pharmacological intervention) are provided. |
| FILED | Friday, May 20, 2022 |
| APPL NO | 18/562949 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 31/137 (20130101) A61K 31/485 (20130101) A61K 38/26 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252608 | OKADA et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hideho OKADA (Pittsburgh, Pennsylvania); Walter STORKUS (Glenshaw, Pennsylvania) |
| ABSTRACT | The invention provides a peptide derived from the interleukin-13 receptor α2, which serves as a HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope. The invention can be used as a vaccine for glioma and can be formulated into compositions for medical or veterinary use. In addition, the invention provides the use of a peptide derived from the Eph family of tyrosine kinase receptors which can be also used as a vaccine for glioma and can be formulated into compositions for medical or veterinary use. |
| FILED | Wednesday, June 28, 2023 |
| APPL NO | 18/342884 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 2039/572 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/7155 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252610 | PICKING et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wendy L. PICKING (Lawrence, Kansas); William D. PICKING (Lawrence, Kansas); Robert K. ERNST (Silver Spring, Maryland) |
| ABSTRACT | Disclosed are compositions comprising a fusion polypeptide comprising i) a fusion of a needle tip protein or an antigenic fragment thereof and/or a translocator protein or an antigenic fragment thereof from a Type III secretion system (T3SS) of a Gram negative bacteria and ii) the A1 subunit of the labile toxin (LTA1) from enterotoxigenic Escherichia coli or cholera toxin, and methods of their use. |
| FILED | Monday, May 23, 2022 |
| APPL NO | 18/562170 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/099 (20130101) A61K 39/104 (20130101) Original (OR) Class A61K 39/0208 (20130101) A61K 39/0275 (20130101) A61K 39/0283 (20130101) A61K 39/0291 (20130101) A61K 2039/55566 (20130101) A61K 2039/55572 (20130101) A61K 2039/55583 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Peptides C07K 14/21 (20130101) C07K 14/24 (20130101) C07K 14/25 (20130101) C07K 14/28 (20130101) C07K 14/195 (20130101) C07K 14/235 (20130101) C07K 14/245 (20130101) C07K 14/255 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252617 | Saunders et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Saunders (Durham, North Carolina); Barton F. Haynes (Durham, North Carolina) |
| ABSTRACT | The invention is directed to coronavirus based immunogens, including immunogens comprising spike protein and or domains thereof, comprised in multimeric complexes. Provided are also methods of using these immunogens to induce immunogenic responses in a subject. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 18/276798 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/575 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) C07K 14/435 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/20022 (20130101) C12N 2770/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252644 | Hansen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Danmarks Tekniske Universitet (Kongens Lyngby, Denmark); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ulla Kring Hansen (Kongens Lyngby, Denmark); Sine Reker Hadrup (Kongens Lyngby, Denmark); Paul Tuan-Xuan Nghiem (Kongens Lyngby, Denmark) |
| ABSTRACT | The present invention relates to a method for producing a person-tailored T cell composition by in vitro stimulation and expansion of T cells comprising the steps of i) providing at least one identified HLA haplotype from a subject; ii) preparing at least one APC comprising at least one HLA haplotype corresponding to said at least one identified HLA haplotype; and at least one antigenic peptide matched to said at least one HLA haplotype; wherein said at least one antigenic peptide comprises an epitope from Merkel cell polyomavirus, said epitope originates from large T antigen (LTA), small T antigen (STA) or the shared region (CT) of LTA and STA; iii) providing a sample comprising T cells, iv) contacting said sample with an expansion solution comprising at least one APC as prepared in step ii, v) stimulating and expanding T cells with specificity for said at least one antigenic peptide comprised on at least one APC in culture, and optionally harvesting the T cells from the culture, to obtain a person-tailored T cell composition. |
| FILED | Thursday, June 02, 2022 |
| APPL NO | 18/565040 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) A61K 39/464838 (20230501) Original (OR) Class Peptides C07K 14/005 (20130101) C07K 14/70539 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2501/2302 (20130101) C12N 2501/2321 (20130101) C12N 2502/1157 (20130101) C12N 2710/22022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252652 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lei Wang (San Francisco, California); Shanshan Li (San Francisco, California) |
| ABSTRACT | Provided herein are, inter alia, compounds of Formula (I): biomolecules (e.g., proteins, lipids, RNA, glycans) comprising the compounds; bioconjugates comprising the compounds; processes for preparing the compounds, biomolecules, and bioconjugates; and their uses. |
| FILED | Thursday, June 02, 2022 |
| APPL NO | 18/565032 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/545 (20170801) Original (OR) Class Heterocyclic Compounds C07D 207/416 (20130101) Peptides C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/154 (20130101) Enzymes C12Y 601/01026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252659 | Wei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wei-Zen Wei (Grosse Pointe Farms, Michigan); Richard F. Jones (Deceased) (Fayetteville, New York); Joyce Reyes (Rochester Hills, Michigan); Heather Gibson (Madison Heights, Michigan) |
| ABSTRACT | Only limited success has been previously achieved from cancer vaccines targeting unmodified tumor-associated self-antigens and new compositions and methods are needed. Immunogenic compositions and methods of use thereof are provided according to the present disclosure which include a protein effective to stimulate immune activity against a tumor-associated self-antigen, or a variant thereof which is a tumor-associated self-antigen. |
| FILED | Monday, December 04, 2023 |
| APPL NO | 18/528165 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 35/76 (20130101) A61K 38/28 (20130101) A61K 39/39 (20130101) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 47/58 (20170801) Original (OR) Class A61K 47/543 (20170801) A61K 47/544 (20170801) A61K 47/6909 (20170801) A61K 47/6915 (20170801) A61K 47/6921 (20170801) A61K 2039/585 (20130101) Acyclic or Carbocyclic Compounds C07C 227/16 (20130101) C07C 229/22 (20130101) Peptides C07K 16/2863 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 120/36 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 81/027 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252662 | LU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zheng-Rong LU (Cleveland, Ohio); Songqi GAO (Cleveland, Ohio) |
| ABSTRACT | An anticancer peptide conjugate is described that comprises the following formula: P-L-A wherein: P is a peptide that includes an amino acid sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, or variants thereof in which one or more L-amino acids have been replace with a corresponding D-amino acid; A is an antitumor agent; and L is an optional linker that covalently links the peptide to the antitumor agent, and pharmaceutically acceptable salts thereof. Methods of using the anticancer peptide conjugates to treat cancer are also described. |
| FILED | Friday, May 20, 2022 |
| APPL NO | 18/561384 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/64 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252677 | Percec et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Virgil Percec (Philadelphia, Pennsylvania); Drew Weissman (Philadelphia, Pennsylvania); Dapeng Zhang (Philadelphia, Pennsylvania); Elena Atochina-Vasserman (Huntingdon Valley, Pennsylvania); Devendra Maurya (Philadelphia, Pennsylvania); Qi Xiao (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention relates to amphiphilic Janus dendrimers which may form nanoparticles. The invention also relates to methods of inducing an adaptive immune response in a subject comprising administering to the subject an effective amount of a composition comprising at least one nucleoside-modified RNA encoding at least one antigen and at least one amphiphilic Janus dendrimer and to methods of delivering an agent to a subject in need thereof, said method comprising the step of delivering to the subject a composition comprising an agent encapsulated by a nanoparticle. |
| FILED | Tuesday, May 24, 2022 |
| APPL NO | 18/563503 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 39/385 (20130101) A61K 47/542 (20170801) A61K 47/545 (20170801) A61K 48/0033 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252689 | KRAUS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | W. Lee KRAUS (Dallas, Texas); Keun Woo RYU (Dallas, Texas); Sridevi CHALLA (Dallas, Texas) |
| ABSTRACT | Provided herein are split reporter systems for detecting poly-ADP ribose polymerase activity in living systems. In some aspects, the split reporter systems comprise a first fusion protein comprising a first fragment of a reporter protein functionally linked to a first poly-ADP ribose binding moiety; and a second fusion protein comprising a second fragment of the reporter protein functionally linked to a second poly-ADP ribose binding moiety wherein the first and second fragments of the reporter protein are each non-functional and capable of recombining, optionally in the presence of a substrate, to form a functional reporter protein capable of producing a detectable signal. Also provided are methods of use thereof. |
| FILED | Wednesday, May 18, 2022 |
| APPL NO | 18/561044 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) A61K 49/0045 (20130101) A61K 49/0047 (20130101) Original (OR) Class A61K 49/0056 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1077 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) Enzymes C12Y 204/0203 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/91142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252696 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgetown University (Washington, District of Columbia); The USA as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia); The USA as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Jill P. Smith (Camp Hill, Pennsylvania); Stephan Stern (Frederick, Maryland) |
| ABSTRACT | A method that includes detecting the presence of a pancreatic intraepithelial neoplasia lesion in a subject in vivo comprising administering to the subject a construct, or a pharmaceutically acceptable salt thereof, wherein the construct comprises: (a) a polyethylene glycol-block-poly(L-lysine) polymer moiety, wherein the polyethylene glycol is thiol-functionalized; (b) a cholecystokinin-B (CCK-B) receptor ligand coupled to the polyethylene glycol of the polymer moiety; and (c) a detectable moiety complexed with, or conjugated to, the poly(L-lysine) of the polymer moiety, wherein the construct is neutralized. |
| FILED | Wednesday, May 26, 2021 |
| APPL NO | 17/925582 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0056 (20130101) A61K 51/088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252697 | Atreya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Se (Bethesda, Maryland); The University of Strathclyde (Glasgow, United Kingdom) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Se (Bethesda, Maryland); The University of Strathclyde (Glasgow, United Kingdom) |
| INVENTOR(S) | Chintamani Atreya (Bethesda, Maryland); Michelle Maclean (Renfrewshire, United Kingdom); John G. Anderson (Glasgow, United Kingdom); Scott J. MacGregor (Glasgow, United Kingdom) |
| ABSTRACT | Disclosed herein are methods and devices for the inactivation of pathogens (e.g., bacteria, viruses, etc.) in ex vivo stored blood products, such as plasma and/or platelets, by means of directing visible light radiation from an illuminating device into blood product storage containers in order to achieve effective pathogen inactivation without the presence of an added photosensitising agent in the blood product. An exemplary apparatus includes a control unit that operates a light source that emits light in the wavelength region of about 380-500 nm which is directed onto blood product storage bags at sufficient intensity to penetrate the bag material and the opaque blood product therein in order to inactivate pathogens in the blood product but at dose levels that cause no significant detrimental effects on the blood product. |
| FILED | Monday, April 08, 2024 |
| APPL NO | 18/629098 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/0052 (20130101) Original (OR) Class A61L 2/084 (20130101) A61L 2202/22 (20130101) A61L 2202/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252720 | Moalli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Magee-Womens Research Institute and Foundation (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Magee-Womens Research Institute and Foundation (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Pamela Moalli (Pittsburgh, Pennsylvania); Vivian Sung (Providence, Rhode Island); Jeffrey Morgan (Sharon, Massachusetts) |
| ABSTRACT | Embodiments relate to a living tissue graft derived from autologous cells used to provide support or to strengthen/reinforce compromised tissue. The living tissue graft comprises both cells and extracellular matrix (ECM) and overcomes problems related to foreign body responses to synthetic materials and rejection reactions to allograft tissue. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/426754 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/3604 (20130101) A61L 27/3633 (20130101) A61L 27/3679 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252726 | Cullen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); Wisberty J. Gordian-Velez (Philadelphia, Pennsylvania); H. Isaac Chen (Penn Valley, Pennsylvania); Jason A. Burdick (Philadelphia, Pennsylvania) |
| ABSTRACT | In various aspects and embodiments the present disclosure provides a construct comprising a pre-formed neural network, the construct comprising a micro-column comprising an outer sheath comprising a hyaluronic acid (HA) hydrogel, and a core comprising an extracellular matrix (ECM); a plurality of neurons within the micro-column. The present disclosure further provides methods of making and using the same. |
| FILED | Wednesday, May 18, 2022 |
| APPL NO | 18/561507 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/58 (20130101) A61L 27/383 (20130101) A61L 27/3633 (20130101) A61L 27/3675 (20130101) A61L 27/3878 (20130101) Computer Systems Based on Specific Computational Models G06N 3/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252730 | Lindo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Simergent LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steve J. Lindo (Chicago, Illinois); Richard A. Pendergraft (Norman, Oklahoma); Jacob Henderson (Oklahoma City, Oklahoma) |
| ABSTRACT | An automated peritoneal dialysis (APD) device, system and method is provided, which utilizes mechanisms to admix customized dialysate solutions from multiple sources, while maximizing volumetric accuracy. The present automated peritoneal dialysis (APD) device can accomplish these goals all within the convenience and comfort of the patient's home utilizing filtered tap water. |
| FILED | Monday, March 25, 2024 |
| APPL NO | 18/614836 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/155 (20220501) A61M 1/159 (20220501) A61M 1/267 (20140204) A61M 1/282 (20140204) A61M 1/285 (20130101) A61M 1/287 (20130101) Original (OR) Class A61M 1/1565 (20220501) A61M 1/1605 (20140204) A61M 1/1654 (20130101) A61M 1/1656 (20130101) A61M 2205/52 (20130101) A61M 2205/121 (20130101) A61M 2205/125 (20130101) A61M 2205/128 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 22/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253011 | Haynes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); The Connecticut Agricultural Experiment Station (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christy Haynes (Minneapolis, Minnesota); Riley Lewis (St. Paul, Minnesota); Cheng-Hsin Huang (Minneapolis, Minnesota); Sara Nason (North Haven, Connecticut); Nubia Zuverza-Mena (Hamden, Connecticut); Jason White (Prospect, Connecticut) |
| ABSTRACT | A method of producing nanoscale carbon dots suitable for uptake by a plant and with increased affinity to Per- and poly-fluoroalkyl substances wherein the nanoscale carbon dots are synthesized through a hydrothermal reaction of branched polyethyleneimine and citric acid producing polyethyleneimine-based carbon dots. |
| FILED | Thursday, February 01, 2024 |
| APPL NO | 18/430265 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/205 (20130101) Original (OR) Class B01J 20/3078 (20130101) B01J 20/28007 (20130101) Reclamation of Contaminated Soil B09C 1/08 (20130101) B09C 2101/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/318 (20170801) C01B 32/342 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253050 | GANGULI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anurup GANGULI (San Diego, California); Rashid BASHIR (Champaign, Illinois); Panagiotis Z. ANASTASIADIS (Jacksonville, Florida); George VASMATZIS (Oronoco, Minnesota) |
| ABSTRACT | Provided are methods and related devices for preparing a cell and tissue culture, including a hanging drop culture. Microwells are specially loaded with cell mixtures using a removable reservoir and forcing cells into the underlying microwells. The removable reservoir is removed and the cells partitioned into the individual microwells and covered by an immiscible layer of fluid. The microwells and immiscible layer is inverted and the cells in the microwells cultured. The microwells may have shape-controlling elements to control the three-dimensional shape of the culture. |
| FILED | Monday, December 18, 2023 |
| APPL NO | 18/543913 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0262 (20130101) B01L 3/5088 (20130101) Original (OR) Class B01L 9/523 (20130101) B01L 2400/024 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253990 | Apollonio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Third Pole, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Third Pole, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Benjamin J. Apollonio (Lunenburg, Massachusetts); Frank Heirtzler (Londonderry, New Hampshire); Nathaniel G. Jackson (Lexington, Massachusetts); Gregory W. Hall (Belmont, Massachusetts) |
| ABSTRACT | Systems and methods for nitric oxide (NO) delivery are provided. A NO delivery system can include one or more pairs of electrodes configured to ionize a reactant gas into an NO-containing product gas, a delivery line to deliver at least a portion of the product gas into an inspiratory flow of gas, and a controller. The controller is configured to control an amount of NO in the product gas generated by the one or more pairs of electrodes using one or more parameters as input to the at least one controller. One of the parameters is a dilution value derived as a function of an inspiratory flow rate and a target inspiratory gas NO concentration level. The dilution value is used by the controller to set a flow rate of the product gas injected into the inspiratory flow and to determine a target concentration of NO in the product gas. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/427703 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/122 (20140204) A61M 2202/0275 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/203 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254076 | DONG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yizhou DONG (Dublin, Ohio); Chang WANG (Dublin, Ohio); Yuebao ZHANG (Dublin, Ohio); Yonger XUE (Columbus, Ohio) |
| ABSTRACT | Disclosed herein are lipid formulations that can be used in drug delivery and screening. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 18/557218 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1617 (20130101) A61K 9/4858 (20130101) A61K 47/18 (20130101) A61K 47/20 (20130101) A61K 48/0008 (20130101) Acyclic or Carbocyclic Compounds C07C 211/38 (20130101) C07C 211/49 (20130101) C07C 237/08 (20130101) C07C 237/20 (20130101) Original (OR) Class C07C 317/30 (20130101) Heterocyclic Compounds C07D 209/20 (20130101) C07D 401/04 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254077 | D'Armiento |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jeanine D'Armiento (New York, New York) |
| ABSTRACT | The present invention relates to the treatment of chronic obstructive pulmonary disease (COPD). More specifically, embodiments of the invention provide a pharmaceutical carrier and a compound that inhibit the induction of MMP-1 expression by cigarette smoke. |
| FILED | Tuesday, March 05, 2024 |
| APPL NO | 18/596300 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/17 (20130101) A61K 31/18 (20130101) Acyclic or Carbocyclic Compounds C07C 275/10 (20130101) Original (OR) Class C07C 311/04 (20130101) C07C 311/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254087 | WALLACH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Saint Joseph's University (Philadelphia, Pennsylvania); The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason WALLACH (Philadelphia, Pennsylvania); John MCCORVY (Milwaukee, Wisconsin); Adam HALBERSTADT (Oakland, California) |
| ABSTRACT | Disclosed herein are novel serotonin 5-HT2A receptor agonists with selectivity for the 5-HT2A receptor subtype over other serotonin receptors. Some of these 5-HT2A agonists exhibit functional selectivity and preferentially activate arrestin signaling over G protein-mediated signaling. Also disclosed are pharmaceutical compositions of the compounds and methods of treating certain diseases or conditions. |
| FILED | Wednesday, May 11, 2022 |
| APPL NO | 18/560113 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/135 (20130101) A61K 31/341 (20130101) A61K 31/343 (20130101) A61K 31/357 (20130101) A61K 31/381 (20130101) A61K 31/415 (20130101) A61K 31/472 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 217/60 (20130101) C07C 2602/08 (20170501) C07C 2602/10 (20170501) Heterocyclic Compounds C07D 213/38 (20130101) C07D 215/12 (20130101) Original (OR) Class C07D 217/04 (20130101) C07D 231/12 (20130101) C07D 307/52 (20130101) C07D 307/91 (20130101) C07D 317/64 (20130101) C07D 333/20 (20130101) C07D 333/76 (20130101) C07D 493/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254107 | Weeks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Weeks (Carrboro, North Carolina); Jeffrey Aubé (Chapel Hill, North Carolina); Kelin Li (Chapel Hill, North Carolina); Meredith Zeller (Durham, North Carolina) |
| ABSTRACT | The disclosure is directed to compounds that bind to a target RNA molecule, such as a TPP riboswitch, compositions comprising the compounds, and methods of making and using the same. The compounds contain two structurally different fragments that allow for binding with the target RNA at two different binding sites thereby producing a higher affinity binding ligand compared to compounds that only bind to a single RNA binding site. |
| FILED | Wednesday, June 01, 2022 |
| APPL NO | 18/563675 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/498 (20130101) Heterocyclic Compounds C07D 241/42 (20130101) C07D 401/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254127 | Emrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (BOSTON, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Todd Emrick (South Deerfield, Massachusetts); Matthew Skinner (Amherst, Massachusetts); Sarah M. Ward (Amherst, Massachusetts); Banishree Saha (Greenfield, Massachusetts) |
| ABSTRACT | A temozolomide compound according to formula (I) is described, wherein R1, L1, and X are defined herein. The temozolomide compound can be used to prepare polymers comprising temozolomide. Additionally, the polymers comprising temozolomide can be particularly useful in the treatment of certain diseases. |
| FILED | Wednesday, January 10, 2024 |
| APPL NO | 18/408929 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/787 (20130101) A61K 47/58 (20170801) A61K 47/60 (20170801) A61K 47/545 (20170801) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 22/10 (20130101) C08F 220/365 (20200201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254134 | Romo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kevin SHUFORD (Waco, Texas); Haoran XUE (Waco, Texas); Emviaee CALIXTE (Waco, Texas); Kenneth HULL (Waco, Texas); Morgan JOUANNEAU (Waco, Texas); ROMO, Daniel (Waco, Texas) |
| ASSIGNEE(S) | Baylor University (Waco, Texas) |
| INVENTOR(S) | Daniel Romo (Waco, Texas); Kevin Shuford (Waco, Texas); Haoran Xue (Waco, Texas); Emvia Calixte (Waco, Texas); Kenneth Hull (Waco, Texas); Morgan Jouanneau (Waco, Texas) |
| ABSTRACT | Agelastatin compounds, methods for making agelastatin compounds, and methods for using agelastatin compounds. |
| FILED | Wednesday, May 11, 2022 |
| APPL NO | 18/560292 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4985 (20130101) Heterocyclic Compounds C07D 487/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254157 | BACHMANN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian O. BACHMANN (Nashville, Tennessee); Benjamin REISMAN (Nashville, Tennessee); Michael SAVONA (Nashville, Tennessee); Haley RAMSEY (Nashville, Tennessee); Gary SULIKOWSKI (Nashville, Tennessee) |
| ABSTRACT | Disclosed herein are macrolide compounds with ATP synthase inhibitory activity. The macrolides may be used to treat cancer and other proliferative disorders. The macrolides may be used to treat leukemia, including acute myeloid leukemia. The macrolides may be used to treat cancer, including AML, in a patient that has developed multidrug resistance. In some embodiments, the macrolide is a derivative of ammocidin A. |
| FILED | Friday, May 27, 2022 |
| APPL NO | 18/563804 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 17/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254166 | GOLDSTEIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven A. GOLDSTEIN (Irvine, California); Ruiming Zhao (Irvine, California) |
| ABSTRACT | In alternative embodiments, provided are compositions, including products of manufacture and kits, and methods, for inhibiting the ability of neutrophils, or polymorphonuclear leukocytes (PMNs), to release reactive oxygen species (ROS), thus also inhibiting or ameliorating neutrophil (PMN) contribution to an inflammatory response, thus also treating, ameliorating or preventing neutrophil (PMN)-meditated inflammatory-related pathologies such as acute respiratory distress syndrome (ARDS), including ARDS caused by a viral infection such as COVID-19. |
| FILED | Friday, May 27, 2022 |
| APPL NO | 18/564822 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 37/06 (20180101) Peptides C07K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254169 | SHIKUMA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation (San Diego, California); J. CRAIG VENTER INSTITUTE (La Jolla, California); ETH ZURICH (Zurich, Switzerland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas J. SHIKUMA (San Diego, California); Sinem BEYHAN (La Jolla, California); Martin PILHOFER (Zurich, Switzerland); Charles ERICSON (Zurich, Switzerland) |
| ABSTRACT | Provided are compositions, kits, and methods for delivering a proteinaceous cargo, or a protein or a peptide, or a drug or a marker, to or into a cell or to an individual in need thereof. Methods comprise use of: a substantially purified or isolated bacterial Contractile Injection Systems (CIS) or Metamorphosis Associated Contractile structure; a recombinant bacterial Contractile Injection Systems (CIS) or Metamorphosis Associated Contractile structure (MACs); a liposome or lipid-comprising nanoparticle incorporating or expressing on its outer surface the substantially purified or isolated bacterial CIS or MACs, or the recombinant bacterial CIS or MACs; a protoplast or a spheroplast incorporating or expressing on its outer surface the substantially purified or isolated bacterial CIS or MACs, or the recombinant bacterial CIS or MACs; a cell expressing on its extracellular surface the substantially purified or isolated bacterial CIS or MACs, or the recombinant bacterial CIS or MACs. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 17/294656 |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Original (OR) Class C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254174 | WELTZIN |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Alaska Fairbanks (Fairbanks, Alaska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MAEGAN WELTZIN (Fairbanks, Alaska) |
| ABSTRACT | Disclosed are peptides comprising a first portion, a second portion and a third portion, wherein at least the second portion is a portion of a RVG peptide, and wherein at least one of the first or third portions is a nAChR subtype selective peptide In some aspects, the nAChR subtype selective peptide can be from an α-neurotoxin. Disclosed are peptides comprising a first portion, a second portion and a third portion, wherein the first portion is a nicotinic acetylcholine receptor (nAChR) subtype selective portion of an α-neurotoxin, wherein the second portion is a portion of a rabies viral glycoprotein (RVG) peptide, and wherein the third portion is a nicotinic acetylcholine receptor (nAChR) subtype selective portion of an α-neurotoxin. In some aspects, the RVG peptide is a cell penetrating portion. Disclosed are methods of using these peptides. |
| FILED | Thursday, January 25, 2024 |
| APPL NO | 18/422865 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/6415 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/24 (20180101) Peptides C07K 14/005 (20130101) C07K 14/46 (20130101) Original (OR) Class C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/3513 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254178 | Ildefonso et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Cristhian J. Ildefonso (Gainesville, Florida); Alfred S. Lewin (Gainesville, Florida); Qiuhong Li (Gainesville, Florida) |
| ABSTRACT | The present invention provides methods and compositions for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration, ocular neovascularization, or ocular inflammation. In an exemplary embodiment, a method is disclosed that involves administering an expression vector that delivers a secretable and cell penetrating CARD to a subject in need of treatment or prevention of age-related macular degeneration or another condition involving macular degeneration or ocular neovascularization. |
| FILED | Friday, June 30, 2023 |
| APPL NO | 18/345226 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/00 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) Peptides C07K 14/4703 (20130101) Original (OR) Class C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2740/15041 (20130101) C12N 2750/14141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254179 | Alexander et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Katherine Alexander (Philadelphia, Pennsylvania); Shelley Berger (Philadelphia, Pennsylvania); Celeste Simon (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention provides polypeptides, compositions, and methods useful for the inhibition of transcription factor/DNA-speckle association and for manipulation of nuclear speckle content. Also included are methods of treating speckle related cancers in subjects in need thereof. |
| FILED | Friday, January 19, 2024 |
| APPL NO | 18/418058 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/163 (20130101) C07K 14/4703 (20130101) Original (OR) Class C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254181 | Martin |
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| FUNDED BY |
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| APPLICANT(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Paul Taylor Martin (Bexley, Ohio) |
| ABSTRACT | Products and methods for treating dystroglycanopathies and laminin-deficient muscular dystrophies are provided. In the methods, a protein including a linker domain, such as the heparin-binding domain of Heparin-Binding Epidermal Growth Factor-Like Growth Factor (HBEGF), is delivered to patients. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 17/254055 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Peptides C07K 14/78 (20130101) C07K 14/485 (20130101) Original (OR) Class C07K 14/4707 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254190 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| INVENTOR(S) | Sanghyun Kim (Rockville, Maryland); Nikolaos Zacharakis (Gaithersburg, Maryland); Steven A. Rosenberg (Potomac, Maryland); Frank J. Lowery, III (Clarksburg, Maryland); Maria R. Parkhurst (Ellicott City, Maryland) |
| ABSTRACT | Disclosed are isolated or purified T cell receptors (TCRs) having antigenic specificity for human p53C135Y, human p53R175H, or human p53M237I. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 18/289596 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) A61K 39/4632 (20230501) A61K 39/464451 (20230501) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254205 | Kobie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | James J. Kobie (Rochester, New York); Luis Martinez-Sobrido (Rochester, New York); Michael Piepenbrink (Rochester, New York); Aitor Nogales (Rochester, New York) |
| ABSTRACT | The present invention relates to broadly neutralizing anti-influenza monoclonal antibodies or antigen-binding fragments thereof. The present invention further relates to therapeutic uses of the isolated antibody or the antigen-binding fragment thereof. |
| FILED | Tuesday, March 05, 2024 |
| APPL NO | 18/596217 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/52 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254206 | Scheid et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Johannes Scheid (New York, New York); Michel Nussenzweig (New York, New York); Pamela J. Bjorkman (Altadena, California); Ron Diskin (Rehovot, Israel) |
| ABSTRACT | The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for prophylaxis, and methods for diagnosis and treatment of HIV infection. |
| FILED | Wednesday, March 06, 2024 |
| APPL NO | 18/597018 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1045 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/10 (20130101) C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254208 | Kyratsous et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regeneron Pharmaceuticals, Inc. (Tarrytown, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christos Kyratsous (Irvington, New York); Chia-Yang Lin (Scarsdale, New York); Andrew Murphy (Croton-on-Hudson, New York); Brinda Prasad (Princeton, New Jersey); Neil Stahl (Carmel, New York) |
| ABSTRACT | According to certain embodiments, the present disclosure provides bispecific antigen-binding molecules comprising a first antigen-binding domain that specifically binds a target antigen and a second antigen binding domain that binds a complement component. In certain embodiments, the bispecific antigen-binding molecules of the present disclosure are capable of binding to the target antigen with an EC50 of about 10 nM or less, and/or are capable of promoting complement deposition on the target antigen with an EC50 of about 10 nM. In certain embodiments, the bispecific antigen-binding molecules of the disclosure are useful for treating diseases in which inhibition or reduction of the growth of an infectious agent or cancer cell is desired and/or therapeutically beneficial. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 17/430117 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) C07K 16/1214 (20130101) C07K 16/1271 (20130101) Original (OR) Class C07K 16/2878 (20130101) C07K 16/2887 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254209 | SMITH |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott A. SMITH (White Bluff, Tennessee) |
| ABSTRACT | The present disclosure is directed to human monoclonal IgE antibodies, and IgG antibodies engineered therefrom. Such engineered antibodies can be used to blunt pathologic IgE responses in subjects, such as in the detection, treatment and prevention of allergies, such as those to peanut allergens. |
| FILED | Wednesday, March 09, 2022 |
| APPL NO | 18/549844 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/35 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/08 (20180101) Peptides C07K 16/16 (20130101) Original (OR) Class C07K 2317/21 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 2333/415 (20130101) G01N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254218 | Zaidi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mone Zaidi (New York, New York); Keqiang Ye (Atlanta, Georgia) |
| ABSTRACT | The present disclosure provides compositions and methods for treating neurodegenerative diseases, in particular, Alzheimer's Disease, by inhibiting FSH in a subject in need thereof. A method comprising of treating Alzheimer's Disease (AD), preventing the onset of AD, or reducing cognitive or functional decline in AD, in a subject in need or at risk thereof. |
| FILED | Thursday, July 21, 2022 |
| APPL NO | 18/290633 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/26 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254219 | LIU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bin LIU (San Francisco, California); Nam-Kyung LEE (Daejeon, South Korea); Scott BIDLINGMAIER (San Francisco, California); Yang SU (South San Francisco, California) |
| ABSTRACT | Antibodies are provided herein that agonize Wnt signaling, do not compete with a Wnt ligand for LRP6 binding, and activate Wnt signaling in the presence of inhibitors. Methods for promoting cell differentiation and tissue regeneration using the disclosed antibodies are also provided. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 18/693416 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/10 (20180101) Peptides C07K 16/28 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/75 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) C12N 15/1055 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254288 | Chiu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| INVENTOR(S) | Daniel T. Chiu (Seattle, Washington); Changfeng Wu (Changchun, China PRC); Yu Rong (Seattle, Washington); Yong Zhang (Seattle, Washington); Yi-Che Wu (Seattle, Washington); Yang-Hsiang Chan (Seattle, Washington); Xuanjun Zhang (Linkoping, Sweden); Jiangbo Yu (Seattle, Washington); Wei Sun (Seattle, Washington) |
| ABSTRACT | Polymers, monomers, chromophoric polymer dots and related methods are provided. Highly fluorescent chromophoric polymer dots with narrow-band emissions are provided. Methods for synthesizing the chromophoric polymers, preparation methods for forming the chromophoric polymer dots, and biological applications using the unique properties of narrow-band emissions are also provided. |
| FILED | Monday, May 15, 2023 |
| APPL NO | 18/317288 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0019 (20130101) A61K 49/0067 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/32 (20130101) Original (OR) Class C08G 79/00 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 69/105 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/587 (20130101) G01N 2021/6439 (20130101) Organic electric solid-state devices H10K 50/11 (20230201) H10K 85/10 (20230201) H10K 85/113 (20230201) H10K 85/115 (20230201) H10K 85/151 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254437 | Khoshakhlagh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Parastoo Khoshakhlagh (Cambridge, Massachusetts); Hon Man Alex Ng (Cambridge, Massachusetts); George M. Church (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes. |
| FILED | Friday, February 09, 2024 |
| APPL NO | 18/437775 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/90 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2506/45 (20130101) C12N 2800/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254451 | WAUTHIER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Eliane WAUTHIER (Chapel Hill, North Carolina); Tsunekazu OIKAWA (Chapel Hill, North Carolina); Timothy Anh-Hieu DINH (Chapel Hill, North Carolina); Praveen SETHUPATHY (Chapel Hill, North Carolina); Lola M. REID (Chapel Hill, North Carolina) |
| ABSTRACT | The present disclosure provides a model of human fibrolamellar hepatocellular carcinoma (FL-HCC) cells maintained as a transplantable tumor line in a host and a method to establish a transplantable human FL-HCC tumor line. Methods of ex vivo cultures of the FL-HCC are provided. Methods of diagnosing and treating FL-HCC tumors are also provided. |
| FILED | Thursday, February 08, 2024 |
| APPL NO | 18/436632 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 2207/12 (20130101) A01K 2227/105 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) Original (OR) Class C12N 2503/02 (20130101) C12N 2513/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 305/01098 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5067 (20130101) G01N 33/57438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254455 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jae Keith Joung (Winchester, Massachusetts); Eric M. Mendenhall (Madison, Alabama); Bradley E. Bernstein (Cambridge, Massachusetts); Deepak Reyon (Malden, Massachusetts) |
| ABSTRACT | Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array (TALE) or zinc finger array, and a catalytic domain comprising a sequence that catalyzes histone demethylation, and methods of use thereof. |
| FILED | Wednesday, December 06, 2023 |
| APPL NO | 18/531005 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/195 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 9/0026 (20130101) C12N 9/0083 (20130101) C12N 15/63 (20130101) C12N 15/1093 (20130101) Enzymes C12Y 105/00 (20130101) C12Y 114/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254458 | Verkhusha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vladislav V. Verkhusha (Bronx, New York); Andrii A. Kaberniuk (Bronx, New York) |
| ABSTRACT | This disclosure provides the single-component near-infrared light-controlled IsPadC-PCM-based optogenetic systems for prokaryotic and eukaryotic cells, consisting of an evolved photosensory core module of the Idiomarina sp. bacterial phytochrome, named iLight. The iLight systems are smaller and packable in an adeno-associated virus, as compared to the other near-infrared optogenetic systems based on phytochromes. This disclosure demonstrates the high light-activation efficiency of the developed iLight systems in gene transcription regulation in bacteria, cultured mammalian cells, primary isolated neurons, and living mouse tissue in vivo. The iLight systems also enable crosstalk-free spectral multiplexing with optogenetic systems and fluorescent probes activated or excited by light of the visible spectral range. |
| FILED | Wednesday, May 18, 2022 |
| APPL NO | 18/559495 |
| CURRENT CPC | Peptides C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1241 (20130101) Original (OR) Class C12N 15/113 (20130101) Enzymes C12Y 207/07065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254477 | Devaraj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neal Devaraj (La Jolla, California); Dongyang Zhang (La Jolla, California) |
| ABSTRACT | Provided herein are, inter alia, methods and compositions for linking RNA stem loops. The methods include linking a first RNA stem loop and a second RNA stem loop by way of a preQ1 linking compound. |
| FILED | Tuesday, November 23, 2021 |
| APPL NO | 18/038190 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1077 (20130101) C12N 15/11 (20130101) Original (OR) Class Enzymes C12Y 204/02029 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254509 | Flanigan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Flanigan (Columbus, Ohio); Anthony Aaron Stephenson (Columbus, Ohio) |
| ABSTRACT | The disclosure relates to the field of gene therapy for the treatment of a muscular dystrophy including, but not limited to, Duchenne's muscular dystrophy (DMD), Becker's muscular dystrophy (BMD), or intermediate muscular dystrophy (IMD). More particularly, the disclosure provides nucleic acids, including nucleic acids comprising guide RNAs (gRNAs) and nucleic acids encoding gRNAs to be used with nucleic acids encoding clustered regularly-interspaced short palindromic repeat associated protein 9 (Cas9), and adeno-associated virus (AAV) comprising the nucleic acids to deliver nucleic acids encoding guide RNAs and Cas9 to correct single or multiple DMD exon duplication mutations for use in treating a muscular dystrophy including, but not limited to, DMD, BMD, or IMD, resulting from an exon duplication mutation amenable to CRISPR-Cas9 therapy of the DMD gene. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 18/279169 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2750/14143 (20130101) C12N 2800/80 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254511 | Jaenisch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute of Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rudolf Jaenisch (Brookline, Massachusetts); Bryce Woodbury Carey (New York, New York); Yaqub Hanna (Tel Aviv, Israel) |
| ABSTRACT | The disclosure relates to a method of reprogramming one or more somatic cells, e.g., partially differentiated or fully/terminally differentiated somatic cells, to a less differentiated state, e.g., a pluripotent or multipotent state. In further embodiments the invention also relates to reprogrammed somatic cells produced by methods of the invention, to chimeric animals comprising reprogrammed somatic cells of the invention, to uses of said cells, and to methods for identifying agents useful for reprogramming somatic cells. |
| FILED | Tuesday, November 14, 2023 |
| APPL NO | 18/508761 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) Peptides C07K 14/4705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0696 (20130101) C12N 15/79 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2501/60 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2506/11 (20130101) C12N 2506/115 (20130101) C12N 2510/00 (20130101) C12N 2740/15041 (20130101) C12N 2740/15043 (20130101) C12N 2740/16043 (20130101) C12N 2799/027 (20130101) C12N 2800/108 (20130101) C12N 2840/203 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254514 | Daigle et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ALLEN INSTITUTE (Seattle, Washington) |
| ASSIGNEE(S) | ALLEN INSTITUTE (Seattle, Washington) |
| INVENTOR(S) | Tanya Daigle (Lake Forest Park, Washington); Edward Sebastian Lein (Mercer Island, Washington); Boaz P. Levi (Seattle, Washington); John K. Mich (Seattle, Washington); Amanda Mitchell (Redmond, Washington); Bosiljka Tasic (Seattle, Washington); Jonathan Ting (Lake Forest Park, Washington); Natalie Weed (Aurora, Colorado); Hongkui Zeng (Seattle, Washington) |
| ABSTRACT | Artificial expression constructs for modulating gene expression in targeted central nervous system cell types are described. The artificial expression constructs can be used to express synthetic genes or modify gene expression in GABAergic or glutamatergic neurons within the thalamus. In some cases, the artificial constructs can also be used to express synthetic genes or modify gene expression in neurons within the thalamus as well as a secondary cell type. |
| FILED | Friday, May 20, 2022 |
| APPL NO | 18/563252 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) A01K 2207/12 (20130101) A01K 2227/105 (20130101) A01K 2227/106 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2750/14143 (20130101) C12N 2830/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254541 | Rao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Anjana Rao (La Jolla, California); Mamta Tahiliani (New York, New York); Kian Peng Koh (Jamaica Plain, Massachusetts); Suneet Agarwal (Belmont, Massachusetts); Aravind Iyer (Bethesda, Maryland) |
| ABSTRACT | The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes being capable of converting the cytosine nucleotide 5-methylcytosine into 5-hydroxymethylcytosine by hydroxylation. |
| FILED | Tuesday, February 27, 2024 |
| APPL NO | 18/588930 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1007 (20130101) C12N 2501/70 (20130101) C12N 2501/71 (20130101) C12N 2501/724 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2521/531 (20130101) C12Q 2522/10 (20130101) C12Q 2537/164 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254542 | Rao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Anjana Rao (La Jolla, California); Mamta Tahiliani (New York, New York); Kian Peng Koh (Jamaica Plain, Massachusetts); Suneet Agarwal (Belmont, Massachusetts); Aravind Iyer (Bethesda, Maryland) |
| ABSTRACT | The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TEM3, and CXXC4. The novel activity is related to the enzymes being capable of converting the cytosine nucleotide 5-methylcytosine into 5-hydroxymethylcytosine by hydroxylation. |
| FILED | Tuesday, February 27, 2024 |
| APPL NO | 18/588987 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1007 (20130101) C12N 2501/70 (20130101) C12N 2501/71 (20130101) C12N 2501/724 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2521/531 (20130101) C12Q 2522/10 (20130101) C12Q 2537/164 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254549 | Abate et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHAN ZUCKERBERG BIOHUB, INC. (San Francisco, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam Abate (Oakland, California); Xiangpeng Li (Oakland, California); Benjamin Demaree (Oakland, California) |
| ABSTRACT | The present disclosure provides materials and methods for partitioning cells and high throughput, single-cell multi-omic sequencing. Methods for pathogen detection and identification, microbiome analysis, personalized medicine, environmental analysis where single-cell information is critical are each provided herein. |
| FILED | Thursday, May 26, 2022 |
| APPL NO | 18/290550 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254555 | Keating et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brendan Keating (Philadelphia, Pennsylvania); Bao-Li Chang (Paoli, Pennsylvania); Abraham Shaked (Wynnewood, Pennsylvania) |
| ABSTRACT | The present invention provides compositions, and methods useful for the diagnosis and treatment of acute rejection of cardiac transplant tissue in subjects in need thereof. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/427192 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240254564 — METHODS FOR PREDICTING AND TREATING CHEMORESISTANCE IN SMALL CELL LUNG CANCER PATIENTS
| US 20240254564 | Quintanal Villalonga et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES (New York, New York); SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Álvaro D. Quintanal Villalonga (New York, New York); Charles Michael Rudin (New York, New York); John Thomas Poirier (New York, New York) |
| ABSTRACT | The present disclosure relates to methods for detecting chemoresistant SCLC tumors in a patient and/or methods for determining whether a patient diagnosed with small cell lung cancer (SCLC) will benefit from treatment with chemotherapy. These methods are based on screening a SCLC patient for elevated XP01 expression. The present technology also provides methods for sensitizing SCLC patients to chemotherapy using an inhibitor of XP01. |
| FILED | Wednesday, June 01, 2022 |
| APPL NO | 18/565767 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255409 | ZHAO |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ENRICH BIOSYSTEMS INC. (Branford, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qi ZHAO (West Hartford, Connecticut) |
| ABSTRACT | The present disclosure provides, among other things, methods and devices for single cells/particle selection and isolation from a sample in a light-curable biomatrix gel. The individual cells or particles are observed by microscopy and manipulated and isolated by accurately controlling the light transmission from a liquid crystal display (LCD) oriented under the sample to provide a detailed image of the sample. In some embodiments, selected cells or particles are then immobilized by curing the biomatrix gel with blue/violet light transmitted from a LED pixel array. In other embodiments, the selected cells or particles of interest are allowed to remain mobile. In either embodiment, the individual cells or particles of interest are segregated from and isolated from the remainder of the sample. |
| FILED | Wednesday, March 13, 2024 |
| APPL NO | 18/603625 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/149 (20240101) G01N 15/1433 (20240101) Original (OR) Class G01N 15/1434 (20130101) G01N 2015/1447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255419 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ji-Xin Cheng (Newton, Massachusetts); Hongjian He (Waltham, Massachusetts) |
| ABSTRACT | A system and method for characterizing biological activity in a live cell using a mid-infrared photothermal system and at least one molecular probe. A mid-infrared optical source generates a mid-infrared beam, the mid-infrared beam being directed at the sample to induce a thermal effect. A visible light source generates a light, the light illuminating the sample on the substrate. An optical detector collects the light after interaction with the sample. Biological activity in the sample is characterized based on a spectral shift. Each molecular probe includes an substrate and a chemical functional group. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424524 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) Original (OR) Class G01N 33/581 (20130101) G01N 33/5005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255424 | Tehrani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kayvan Forouhesh Tehrani (Urbana, Illinois); Alejandro De La Cadena (Urbana, Illinois); Stephen A. Boppart (Champaign, Illinois) |
| ABSTRACT | Systems and methods of microscopy include and/or apply a laser light source configured to produce an excitation light; a modulator configured to modulate the excitation light to produce a modulated light; a pulse compressor configured to compress a pulse of the modulated light to produce a pre-compensated light; a beam scanner configured to raster scan the pre-compensated light on a sample; a detector configured to receive a light signal from the sample and produce a detection signal; and a lock-in amplifier configured to receive the detection signal and perform an electronic heterodyne amplification of the detection signal. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424224 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/636 (20130101) Original (OR) Class G01N 2201/12 (20130101) Amplifiers H03F 3/08 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255429 | Cheng |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ji-Xin Cheng (Newton, Massachusetts) |
| ABSTRACT | A stimulated Raman photothermal (SRP) microscope for imaging a sample. A first optical source omits an intensity-modulated pump beam. A second optical source omits an intensity-modulated Stokes beam. The Stokes beam is combined with the pump beam to form a combined beam. The combined beam is directed to the sample to induce a thermal effect caused by the stimulated Raman process. A third optical source emits a probe beam, the probe beam is directed to the sample. An optical detector detects modulation of the probe beam after modulation by the sample to measure an SRP signal. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424128 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2201/105 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255458 | MARKVICKA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric MARKVICKA (Lincoln, Nebraska); Jennifer YENTES (College Station, Texas); Stephen RENNARD (Omaha, Nebraska); Jason FINNEGAN (Lincoln, Nebraska) |
| ABSTRACT | In accordance with some embodiments of the disclosed subject matter, mechanisms (which can, for example, include systems, apparatuses, methods, and media) for predicting a physiological state of a subject using one or more chemical sensors. In some embodiments, a system comprises: a plurality of chemical sensors; a transmitter; and a processor coupled to the plurality of chemical sensors and the transmitter, the processor programmed to: measure, for each of the plurality of sensors, a respective value of a plurality of values; and transmit, via the transmitter, a profile based on the plurality of values to a computing device. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 18/692261 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/22 (20130101) Original (OR) Class G01N 2800/50 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255464 | XU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sheng XU (La Jolla, California); Yue GU (La Jolla, California) |
| ABSTRACT | A method for fabricating a three-dimensional (3D) FET sensor array includes fabricating a two-dimensional (2D) precursor field-effect transistor (FET) sensor array having a plurality of nanoscale or microscale FETs using any suitable microfabrication techniques. Each of the nanoscale or microscale FETs have a kink at which a FET channel is located. The 2D nanoscale or microscale precursor FET sensor array is caused to buckle or fold into a third dimension, also using any suitable technique. |
| FILED | Monday, June 06, 2022 |
| APPL NO | 18/566451 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4148 (20130101) Original (OR) Class G01N 33/5061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255495 | DEITERS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander DEITERS (Pittsburgh, Pennsylvania); Yaniv TIVON (Pittsburgh, Pennsylvania); Mary CACACE (Pittsburgh, Pennsylvania); Savannah ALBRIGHT (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed are chemically modified aptamers comprising an electrophilic group and a handle and methods for using said aptamers to deliver the handle to a target protein, crosslink the aptamer to the target protein, as well as methods of using said aptamers to detect proteins and to treat viral infections or cancer. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 18/557516 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) C12N 15/1048 (20130101) C12N 2310/16 (20130101) C12N 2310/314 (20130101) C12N 2310/531 (20130101) C12N 2310/3511 (20130101) C12N 2310/3517 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 33/5308 (20130101) Original (OR) Class G01N 33/6851 (20130101) G01N 33/56983 (20130101) G01N 33/57488 (20130101) G01N 2333/165 (20130101) G01N 2333/912 (20130101) G01N 2333/974 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255510 | ROTROFF et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel ROTROFF (Pepper Pike, Ohio); Federico AUCEJO (Shaker Heights, Ohio); Courtney HERSHBERGER (Brooklyn Heights, Ohio) |
| ABSTRACT | Metabolites detectable in saliva are useful for indicating disease pathology or a breakdown in liver function. The relative abundance of particular combinations of salivary metabolites derived from machine-learning serve as non-invasive biomarkers of HCC. Combinatorial patterns of salivary metabolites can distinguish healthy individuals from those having cirrhosis and/or hepatocellular carcinoma (HCC). Accordingly, the disclosure provides methods for evaluating the HCC status of a subject and providing treatment appropriate for the HCC status of the subject. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 18/290150 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57438 (20130101) Original (OR) Class G01N 33/57488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255521 | Ramchandran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin); Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ramani Ramchandran (Pewaukee, Wisconsin); Kevin Rarick (Milwaukee, Wisconsin); Rahima Zennadi (Durnham, North Carolina) |
| ABSTRACT | The present invention provides methods and kits for detecting cilium markers in samples and uses thereof for detecting and treating endothelial damage or dysfunction or vascular injury in the subject. In one aspect, the disclosure provides a method of detecting endothelial damage or dysfunction or vascular injury in a subject in need thereof, the method comprising: detecting one or more markers of cilium in a biological sample from the subject, wherein a higher level of cilium detected in the biological sample compared to control indicates endothelial damage or dysfunction or vascular injury. |
| FILED | Friday, May 20, 2022 |
| APPL NO | 18/561185 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/80 (20130101) G01N 33/543 (20130101) G01N 33/6854 (20130101) Original (OR) Class G01N 2333/914 (20130101) G01N 2800/22 (20130101) G01N 2800/50 (20130101) G01N 2800/321 (20130101) G01N 2800/347 (20130101) G01N 2800/2871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255529 | Gordon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Progeria Research Foundation (Peabody, Massachusetts) |
| ASSIGNEE(S) | The Progeria Research Foundation (Peabody, Massachusetts) |
| INVENTOR(S) | Leslie B. Gordon (Peabody, Massachusetts) |
| ABSTRACT | Provided herein is a newly developed immunoassay that can detect progerin with high sensitivity, but which does not detect wildtype lamin A. Applications of the newly developed immunoassay in novel methods for diagnosing, prognosing, and treating progerin-related aging pathologies are also described. |
| FILED | Tuesday, March 05, 2024 |
| APPL NO | 18/595507 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255597 | Theis et al. |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina); Wayne State University (Detroit, Michigan); Board of Trustees of Southern Illinois University (Carbondale, Illinois); NATIONAL INSTITUTES OF HEALTH, NHLBI (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Theis (Raleigh, North Carolina); Mustapha Abdulmojeed (Raleigh, North Carolina); Sören Lehmkuhl (Raleigh, North Carolina); Patrick TomHon (Raleigh, North Carolina); Iuliia Mandzhieva (Raleigh, North Carolina); Eduard Y. Chekmenev (Detroit, Michigan); Isaiah Adelabu (Detroit, Michigan); Mohammad Kabir (Detroit, Michigan); Shiraz Nantogma (Detroit, Michigan); Jessica Ettedgui (Rockville, Maryland); Rolf Eric Swenson (Rockville, Maryland); Boyd Goodson (Carbondale, Illinois) |
| ABSTRACT | In one aspect, the disclosure relates to hyperpolarized target molecules and contrast agents comprising the same, methods of making the same, and methods of imaging using same. In a further aspect, imaging performed using the hyperpolarized target molecules and contrast agent can enable real time monitoring and diagnosis of diseases including various cancers and metabolic disorders. The methods are cryogen-free and inexpensive and can be performed in a short time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Tuesday, July 26, 2022 |
| APPL NO | 18/291681 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4608 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255745 | Kner et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Peter A. Kner (Suwanee, Georgia); Yang Liu (San Jose, California) |
| ABSTRACT | Provided herein are microscopes providing multi-directional illumination of a sample volume by alternately reflecting a light sheet exiting a single objective lens off of multiple reflectors positioned about the sample volume. The provided microscopes exhibit high lateral and axial resolution and are particularly useful for imaging thick samples. Also provided are methods and computer instructions and systems for using the provided microscopes. |
| FILED | Wednesday, January 31, 2024 |
| APPL NO | 18/428342 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/04 (20130101) G02B 21/06 (20130101) Original (OR) Class G02B 21/16 (20130101) G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240256043 | Hochberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leigh Hochberg (Brookline, Massachusetts); John D. Simeral (Providence, Rhode Island); Tyler Singer-Clark (Falmouth, Massachusetts); Ronnie Gross (Portsmouth, Rhode Island); Thomas Hosman (Providence, Rhode Island); Anastasia Kapitonava (Boston, Massachusetts); Rekha Crawford (Providence, Rhode Island) |
| ABSTRACT | Instances of a single brain computer interface (BCI) system can be implemented on multiple devices. An active instance can control the associated device. The instances can each communicate with a neural decoding system that can receive neural signals from a user, process the neural signals, and output a command based on the processed neural signals. A device running the active instance of can be in communication with the neural decoding system to receive a command. The device can include a display, a non-transitory memory storing instructions, and a processor to execute the instructions to: run an instance of a control program; and execute the task based on the command. |
| FILED | Wednesday, March 20, 2024 |
| APPL NO | 18/610476 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/015 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240256267 | Rosinko et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beta Bionics, Inc. (Irvine, California) |
| ASSIGNEE(S) | Beta Bionics, Inc. (Irvine, California) |
| INVENTOR(S) | Michael J. Rosinko (Las Vegas, Nevada); Himanshu Patel (Rancho Santa Margarita, California); Edward R. Damiano (Acton, Massachusetts); Firas H. EI-Khatib (Allston, Massachusetts); David Chi-Wai Lim (Irvine, California) |
| ABSTRACT | An ambulatory medical device can detect a device condition and determine if the device condition satisfies a set of normal operating parameters. If the normal operating parameters are not satisfied, the ambulatory medical device can determine if the device condition stratifies a set of minimum operating parameters. If the minimum operating parameters are satisfied, the ambulatory medical device can maintain a delivery of therapy to a subject and generate an alert based on the device condition. |
| FILED | Wednesday, February 14, 2024 |
| APPL NO | 18/441051 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/172 (20130101) A61M 5/1723 (20130101) A61M 5/14244 (20130101) A61M 5/14248 (20130101) A61M 5/16831 (20130101) A61M 2005/1726 (20130101) A61M 2005/14208 (20130101) A61M 2205/18 (20130101) A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/505 (20130101) A61M 2205/581 (20130101) A61M 2205/582 (20130101) A61M 2205/583 (20130101) A61M 2205/609 (20130101) A61M 2205/3327 (20130101) A61M 2205/3546 (20130101) A61M 2205/3553 (20130101) A61M 2205/3584 (20130101) A61M 2205/3592 (20130101) A61M 2230/201 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) G06F 3/04883 (20130101) G06F 8/61 (20130101) G06F 8/65 (20130101) G06F 8/656 (20180201) Original (OR) Class G06F 21/31 (20130101) G06F 21/84 (20130101) G06F 21/305 (20130101) G06F 21/6245 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) G08B 21/0453 (20130101) G08B 25/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/00 (20180101) G16H 40/40 (20180101) G16H 40/60 (20180101) G16H 40/67 (20180101) G16H 50/30 (20180101) G16H 80/00 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/088 (20130101) H04L 63/101 (20130101) H04L 67/34 (20130101) Wireless Communication Networks H04W 76/10 (20180201) H04W 76/14 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257362 | Presse et al. |
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| FUNDED BY |
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| APPLICANT(S) | Steve Presse (Scottsdale, Arizona); Mohamadreza Fazel (Tempe, Arizona); Zeliha Kilic (Memphis, Tennessee) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Steve Presse (Scottsdale, Arizona); Mohamadreza Fazel (Tempe, Arizona); Zeliha Kilic (Memphis, Tennessee) |
| ABSTRACT | 3D particle tracking and localization provide direct means to monitor details within nano-scale environments. However, a major shortcoming of 3D techniques is the sample induced aberrations due to inhomogeneous refractive index, resulting in distortion of point spread functions (PSFs), which are an important measurement tool required for these tasks in the field. This issue is particularly important when using pre-calibrated PSFs that do not take into account the sample induced aberrations. A system incorporates a Bayesian framework for simultaneous particle tracking and PSF inference directly from a given data. The system is data efficient by taking into account existing sources of uncertainty, such as uncertainty in the shape of the PSF, which is often ignored. The system is benchmarked using a wide range of synthetic and experimental data. |
| FILED | Monday, January 29, 2024 |
| APPL NO | 18/425056 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1429 (20130101) Image Data Processing or Generation, in General G06T 7/277 (20170101) Original (OR) Class G06T 2207/10056 (20130101) G06T 2207/10064 (20130101) G06T 2207/20076 (20130101) G06T 2207/30241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257500 | Frank et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lawrence R. Frank (San Diego, California); Vitaly L. Galinsky (San Diego, California) |
| ABSTRACT | Analysis of complex spatio-temporal data within a dynamic system that includes spatial positions and fields, at least a portion of which are interacting, includes determining values of mean field at every spatial position, determining spatio-temporal eigenmodes in spatial-frequency space assuming interacting fields, and determining spatial and temporal interactions between the eigenmodes. The resulting display indicates space/time localization patterns that are indicative of connectivity within the dynamic system. |
| FILED | Thursday, March 14, 2024 |
| APPL NO | 18/605307 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/5608 (20130101) G01R 33/56341 (20130101) Electric Digital Data Processing G06F 18/2135 (20230101) G06F 18/24133 (20230101) G06F 2218/12 (20230101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/0016 (20130101) G06T 2207/10044 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20048 (20130101) G06T 2207/30016 (20130101) Image or Video Recognition or Understanding G06V 10/7715 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257976 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Edison T. Liu (Bar Harbor, Maine); Francesca Menghi (West Hartford, Connecticut) |
| ABSTRACT | Provided herein, in some embodiments, are methods for classifying the tandem duplicator phenotype of a tumor. |
| FILED | Tuesday, March 12, 2024 |
| APPL NO | 18/602428 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/15 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/10 (20190201) G16B 20/20 (20190201) G16B 40/10 (20190201) G16B 40/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/00 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240259112 | ADIB et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Fadel ADIB (Cambridge, Massachusetts); Waleed AKBAR (Cambridge, Massachusetts); Aline EID (Ann Arbor, Michigan); John Clayton RADEMACHER, JR. (Somerville, Massachusetts); Purui WANG (Cambridge, Massachusetts) |
| ABSTRACT | Described herein is a retroreflective underwater backscatter node comprising a receiver that receives an incoming acoustic signal from a first direction; a reflector that reflects back an incoming acoustic signal in a second direction; and a modulator coupled to the reflector to modulate the reflected incoming acoustic signal as a back-scattered signal. In some embodiments, the first direction and second direction are substantially the same such that the retroreflective underwater backscatter node retro-directs an incoming acoustic signal as a back-scattered signal and incoming and back-scattered acoustic signals propagate in the same but substantially opposite directions. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424033 |
| CURRENT CPC | Transmission H04B 11/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240252980 | Ding et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dong Ding (Idaho Falls, Idaho); Lucun Wang (Idaho Falls, Idaho); Wei Wu (Idaho Falls, Idaho) |
| ABSTRACT | A direct air capture (DAC) reactor system is disclosed and comprises electrochemical cells. One or more of the electrochemical cells comprises a cathode, an anode, and an electrolyte membrane between the cathode and the anode. The electrolyte membrane is configured to transport carbonate ions and oxygenate ions from the cathode to the anode. Additional DAC reactor systems and methods of capturing carbon dioxide from a feedstream using the reactor systems are also disclosed. |
| FILED | Wednesday, May 18, 2022 |
| APPL NO | 18/560909 |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/326 (20130101) Original (OR) Class B01D 71/0271 (20220801) B01D 2257/504 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252991 | Gao et al. |
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| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Feng Gao (Bolingbrook, Illinois); Yuepeng Zhang (Naperville, Illinois); Lei Cheng (Naperville, Illinois); Shi Li (Naperville, Illinois); Seth B. Darling (Chicago, Illinois); Lu Zhang (Naperville, Illinois); Lily A. Robertson (Chicago, Illinois) |
| ABSTRACT | A membrane for selective separation of a target cation from a source liquid containing the target cation and one or more competing ionic species can include a crown ether polymer layer disposed on a cation exchange membrane. The crown ether polymer layer can include a crown ether capable of selectively binding the target cation and a polymer. |
| FILED | Wednesday, January 31, 2024 |
| APPL NO | 18/429019 |
| CURRENT CPC | Separation B01D 61/463 (20220801) B01D 69/125 (20130101) Original (OR) Class B01D 71/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253006 | SHEKHAWAT et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dushyant SHEKHAWAT (Morgantown, West Virginia); David A BERRY (Morgantown, West Virginia); Mark W Smith (Morgantown, West Virginia); Christina WILDFIRE (Morgantown, West Virginia); Victor ABDELSAYED (Morgantown, West Virginia) |
| ABSTRACT | Embodiments relate to methods for enhancing chemical conversions. One or more embodiments relate to a method for enhancing a multi-step chemical conversion reaction. The method includes providing a reactant mixture having one or more reacting specie(s); and providing a catalyst or sorbent having one or more support materials and one or more deposited catalytically active materials. The method further includes applying an electromagnetic field with a prescribed power, frequency, and pulsing strategy specific to interactions of reactant species and an electromagnetic field with at least one of the support materials, sorbent, and catalytically active materials in a particular chemical reaction. |
| FILED | Wednesday, March 06, 2024 |
| APPL NO | 18/596802 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/126 (20130101) Original (OR) Class B01J 37/084 (20130101) B01J 37/344 (20130101) B01J 2219/00038 (20130101) Acyclic or Carbocyclic Compounds C07C 2/76 (20130101) C07C 7/12 (20130101) C07C 15/04 (20130101) C07C 15/06 (20130101) C07C 15/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253018 | GU et al. |
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| FUNDED BY |
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| APPLICANT(S) | GM Global Technology Operations LLC (Detroit, Michigan); BASF Corporation (Mount Olive, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuntao GU (Farmington Hills, Michigan); Michelle H. WIEBENGA (Farmington Hills, Michigan); Raneen TAHA (Sterling Heights, Michigan); Yuejin LI (Edison, New Jersey); Xiaolai ZHENG (Princeton Junction, New Jersey) |
| ABSTRACT | A method of manufacturing a layered catalyst for purifying an exhaust gas stream includes introducing a mixture of colloidal ceria, alumina particles, and a liquid medium into a drying chamber via an atomizer to form atomized droplets of the mixture. A drying gas is introduced into the drying chamber such that the atomized droplets contact the drying gas, the liquid medium is removed from the atomized droplets, and ceria nanoparticles deposit on the alumina particles to form composite catalyst support particles. A catalyst precursor including a rhodium precursor and colloidal ceria is applied to the composite catalyst support particles. The composite catalyst support particles and the catalyst precursor are heated to form the layered catalyst. The layered catalyst includes an alumina substrate, a ceria nanoparticle layer extending substantially continuously over the alumina substrate, and a rhodium catalyst layer including an atomic dispersion of rhodium adsorbed on the ceria nanoparticle layer. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/103053 |
| CURRENT CPC | Separation B01D 53/945 (20130101) B01D 2255/1025 (20130101) B01D 2255/9155 (20130101) B01D 2257/404 (20130101) B01D 2257/502 (20130101) B01D 2257/702 (20130101) B01D 2258/01 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 23/10 (20130101) B01J 23/63 (20130101) Original (OR) Class B01J 35/19 (20240101) B01J 35/23 (20240101) B01J 35/56 (20240101) B01J 37/08 (20130101) B01J 37/024 (20130101) B01J 37/0211 (20130101) B01J 37/0236 (20130101) Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 3/101 (20130101) F01N 3/2803 (20130101) F01N 2370/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253125 | TROKSA et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael John TROKSA (Veradale, Washington); Ziheng WU (Seattle, Washington); Eric S. ELTON (Livermore, California) |
| ABSTRACT | The present disclosure relates to a system for removing an upper layer of powder from a powder bed, wherein the powder bed includes metal powder particles. The system makes use of an electrode subsystem having an electrode and a dielectric layer secured to the electrode. A metallic build plate is used for supporting the powder layer thereon. The electrode subsystem is supported above an upper surface of the powder bed such that the dielectric layer is separated from the upper surface by a gap of a predetermined distance. A power source is coupled to the electrode subsystem and the build plate for supplying a voltage across the electrode subsystem and the build plate. The voltage generates an electric field in the gap which is sufficient to attract and lift a predetermined thickness portion of the powder layer adjacent the upper surface, onto the dielectric layer, to leave a new upper surface on the powder bed. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/162086 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/28 (20210101) B22F 10/68 (20210101) Original (OR) Class B22F 12/60 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 40/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253523 | Conlon et al. |
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| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Brendan M. Conlon (Rochester Hills, Michigan); Zhijian J. Wu (Rochester Hills, Michigan) |
| ABSTRACT | An electric vehicle includes a reconfigurable energy storage system with a first submodule and a second submodule. An interface circuit is operable to transfer a charging power to the reconfigurable energy storage system from a charging station that is external to the electric vehicle. A switching circuit is operable to electrically arrange the first submodule and the second submodule in series or in parallel. A diode is operable to convey the charging power between the first submodule and the second submodule while the reconfigurable energy storage system is arranged in series and the charging power is present. A bias circuit is operable to maintain a reverse bias across the diode while the reconfigurable energy storage system is arranged in series and the charging power is absent. |
| FILED | Thursday, January 26, 2023 |
| APPL NO | 18/159727 |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 3/0046 (20130101) B60L 58/19 (20190201) Original (OR) Class B60L 58/22 (20190201) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253623 | Olin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Delphi Technologies IP Limited (St. Michael, Barbados) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter M. Olin (Ann Arbor, Michigan); Li Tang (Troy, Michigan); Dmitriy S. Semenov (Rochester Hills, Michigan) |
| ABSTRACT | A method for providing a vehicle energy optimization rationality check includes identifying at least one route characteristic of a portion of a route being traversed by a vehicle, determining a vehicle energy consumption profile for the vehicle, determining a profile for a target vehicle speed based on the at least one route characteristic and the vehicle energy consumption profile, determining, based on at least the at least one route characteristic, an alternative target vehicle speed, and, in response to a difference between the target vehicle speed and the alternative vehicle speed being greater than a threshold, performing a default action. |
| FILED | Wednesday, January 10, 2024 |
| APPL NO | 18/408891 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/143 (20130101) Original (OR) Class B60W 2520/10 (20130101) B60W 2530/10 (20130101) B60W 2530/16 (20130101) B60W 2555/20 (20200201) B60W 2556/10 (20200201) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3469 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254283 | TESSONNIER et al. |
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| FUNDED BY |
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| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jean-Philippe TESSONNIER (Ames, Iowa); Brent Howard SHANKS (Ames, Iowa); Eric William COCHRAN (Ames, Iowa); Joseph Eugene HADEL (Ames, Iowa); Marco Nazareno DELL'ANNA (Ames, Iowa); Prerana CARTER (Ames, Iowa); Dustin GANSEBOM (Ames, Iowa) |
| ABSTRACT | The present application is directed to processes for the preparation of compounds of Formulae (I), (IV), and (IVb) as described herein. The application further relates to compounds of Formula (IVb) as described herein. Additional embodiments are directed to a processes for the preparation of polymers of Formulae (X), (XVIII), (XIII), and (XIV) as well as to polymers of Formula (XIII) also described herein. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 18/027480 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/353 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254519 | Baker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrance Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sarah Baker (Dublin, California); Joshuah K. Stolaroff (Oakland, California); Congwang Ye (San Ramon, California) |
| ABSTRACT | In accordance with one embodiment, a mixture for forming polymer-encapsulated whole cells includes: at least one polymer precursor; at least one initiator; and a plurality of whole cells. In further embodiments, a product includes a structure comprising a plurality of whole cells encapsulated by a polymer network, where polymer(s) of the polymer network are cross-linked. The whole cells may include live whole cells, dried whole cells, and/or reconstituted whole cells, and have a characteristic to convert a chemical reactant to a product, where the chemical reactant is a gas (e.g., C1-C3 carbon gases such as methane, carbon dioxide, ethane, etc.) and the product is a liquid (e.g. methanol, etc.). For example, the whole cells may include organisms such as methanotrophic organisms and/or acetogenic anaerobes. |
| FILED | Friday, April 05, 2024 |
| APPL NO | 18/628352 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/003 (20130101) B01J 31/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) C12N 11/082 (20200101) C12N 11/084 (20200101) C12N 11/087 (20200101) C12N 11/089 (20200101) C12N 11/096 (20200101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254634 | HAN |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (AIKEN, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | KAI D. HAN (EVANS, Georgia) |
| ABSTRACT | A method for operating an electrolyzer to produce hydrogen is provided. The method includes providing a compressed gas stream to a vortex tube to generate a cold stream and a hot stream; heating a fluid or a gas with the hot stream from the vortex tube to produce a heated fluid or a heated gas; and providing the heated fluid or heated gas to an electrolyzer. Electrolyzer systems and other methods for operating an electrolyzer are also provided. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/102144 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/042 (20210101) Original (OR) Class C25B 15/021 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0656 (20130101) H01M 16/003 (20130101) H01M 2300/0071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254637 | JIAO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Delaware (Newark, Delaware) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Feng JIAO (Newark, New Jersey); Matthew JOUNY (Easton, Pennsylvania); Jing-Jing LV (Nanjing, China PRC) |
| ABSTRACT | Disclosed herein is a method of electroreduction with a working electrode and counter electrode. The method includes a step of electrocatalyzing carbon monoxide and/or carbon dioxide in the presence of one or more nucleophilic co-reactants in contact with a catalytically active material present on the working electrode, thereby forming one or more carbon-containing products electrocatalytically. |
| FILED | Monday, March 04, 2024 |
| APPL NO | 18/594354 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/23 (20210101) C25B 3/26 (20210101) Original (OR) Class C25B 9/19 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254640 | Sant et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gaurav Sant (Los Angeles, California); Dante Adam Simonetti (Los Angeles, California); Xin Chen (Los Angeles, California); David Jassby (Los Angeles, California); Erika Callagon La Plante (Los Angeles, California); Steven Bustillos (Los Angeles, California); Thomas J. Traynor (Los Angeles, California) |
| ABSTRACT | The present disclosure relates to oxygen-selective anodes and methods for the use thereof. |
| FILED | Wednesday, January 31, 2024 |
| APPL NO | 18/429054 |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/326 (20130101) B01D 2257/504 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 51/40 (20130101) C01G 55/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2004/84 (20130101) C01P 2006/40 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/14 (20130101) C25B 11/075 (20210101) C25B 11/0775 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254898 | Terwilliger |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytneon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neil J. Terwilliger (Cheshire, Connecticut) |
| ABSTRACT | A propulsion system for an aircraft includes a core engine that includes a core flow path where air is compressed in a compressor section, communicated to a combustor section, mixed with a cryogenic fuel and ignited to generate an exhaust gas flow that is expanded through a turbine section. The propulsion system includes a condenser that is arranged along the core flow path and configured to extract water from the exhaust gas flow, an evaporator that is arranged along the core flow path and configured to receive a portion of the water that is extracted by the condenser to generate a steam flow, the steam flow is injected into the core flow path upstream of the turbine section, an electrical device that generates thermal energy, and a heat exchanger where thermal energy from the electrical device is communicated to a cooling water flow. |
| FILED | Monday, June 05, 2023 |
| APPL NO | 18/329091 |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/10 (20130101) B64D 27/24 (20130101) B64D 27/026 (20240101) B64D 33/08 (20130101) Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 15/02 (20130101) Original (OR) Class F01K 17/04 (20130101) F01K 27/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254914 | Staubach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RTX CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph B. Staubach (Colchester, Connecticut); Neil J. Terwilliger (Cheshire, Connecticut); Joseph E. Turney (Amston, Connecticut) |
| ABSTRACT | A turbine engine assembly includes a condenser assembly arranged along the core flow path to extract water from the exhaust gas flow, and an evaporator assembly where thermal energy from the exhaust gas flow is communicated to the water extracted by the condenser assembly to generate a steam flow for injection into the core flow path. The evaporator assembly splits steam generation and cooling functions to increase efficiencies of each function. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/486362 |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/22 (20130101) F02C 3/30 (20130101) Original (OR) Class F02C 7/14 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2260/213 (20130101) F05D 2270/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254920 | TERWILLGER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neil J. TERWILLGER (Cheshire, Connecticut); Joseph B. STAUBACH (Colchester, Connecticut) |
| ABSTRACT | A propulsion system for an aircraft includes a core engine that includes a core flow path where air is compressed in a compressor section, communicated to a combustor section, mixed with a gaseous fuel and ignited to generate an exhaust gas flow that is expanded through a turbine section. A fuel system supplies a fuel to the combustor through a fuel flow path, a first heat exchanger thermally communicates a first heat load into a cooling flow, a turboexpander where a heated cooling flow from the first heat exchanger is expanded to generate shaft power and cooled to provide a cooled cooling flow, and a second heat exchanger thermally communicates a second heat load to the cooled cooling flow that is communicated from the turboexpander, cooling flow from the second heat exchanger is communicated to the combustor section. |
| FILED | Monday, June 05, 2023 |
| APPL NO | 18/329044 |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/22 (20130101) F02C 3/30 (20130101) F02C 7/141 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254958 | Orona et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ocean Motion Technologies, Inc. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander J. Orona (San Diego, California); Boyang Pan (San Diego, California); Leverett Bezanson (Alpine, California); Paul Glick (Santa Cruz, California); Justin Walraven (San Diego, California); Mark Huang (Spring Valley, California); Nathaniel Bell (Tacoma, Washington) |
| ABSTRACT | A wave energy capture system deployed in water converts mechanical motion induced by waves in the water to electrical energy. A controller of the wave energy capture system receives input regarding real-time wave conditions in a vicinity of the wave energy capture system. The controller applies a control model to the received input to select a value of a control parameter for the wave energy capture system, where the control model includes a model that has been trained using machine learning to take wave condition data as input and to output control parameter values selected based on the wave condition data in order to increase an amount of energy captured by the wave energy capture system. The controller implements the selected value of the control parameter on the wave energy capture system. |
| FILED | Wednesday, March 20, 2024 |
| APPL NO | 18/611443 |
| CURRENT CPC | Machines or Engines for Liquids F03B 13/20 (20130101) F03B 15/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255234 | Turney et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph E. Turney (Amston, Connecticut); Kathryn L. Kirsch (Manchester, Connecticut); Robert H. Dold (Monson, Massachusetts); Matthew B. Kennedy (Vernon, Connecticut) |
| ABSTRACT | A heat exchanger includes a plurality of longitudinally-extending first channels and a plurality of second channels fluidly isolated from the plurality of first channels. Each first channels includes a plurality of spiraling internal fins and a plurality of external fins. The internal fins extend from and are integrally formed with the internal walls of the first channel. The external fins connect extend from and are integrally formed with the external walls of the first channels, connecting channels together. The plurality of second channels is defined in part by external walls of the plurality of first channels and the plurality of external fins. |
| FILED | Wednesday, April 10, 2024 |
| APPL NO | 18/631779 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/42 (20130101) Original (OR) Class F28F 2001/428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255241 | PANAS et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Bright Silicon Technologies, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Matthew PANAS (Dublin, California); Cynthia Dawn Walker PANAS (Dublin, California); Robert MCHENRY (San Francisco, California) |
| ABSTRACT | The present disclosure relates to a method for controlling thermal radiation from a component. The method involves arranging a thermally conductive base layer in contact with the component, the base layer including a thermally emissive surface. A plurality of independently controlled shutter elements are movable about at least two orthogonal axes, and between closed and open positions, to change a dimension of a gap separating edges of adjacent ones of the shutter elements. The movements of the shutter elements are controlled about the two orthogonal axes to control the dimensions of the gaps to control thermal radiation emitted through the gaps. |
| FILED | Wednesday, March 20, 2024 |
| APPL NO | 18/611164 |
| CURRENT CPC | Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/007 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/02 (20130101) Original (OR) Class F28F 27/00 (20130101) F28F 2280/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255415 | Giera et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian Giera (Oakland, California); Adam Jaycox (Broomfield, California); Brian Au (El Mont, California); Alex Caviness (Oakland, California); Alexander Blum (Livermore, California); Nishant Ojal (Livermore, California) |
| ABSTRACT | A method is disclosed for selecting an optimal value for an adjustable parameter of a structured light metrology (SLM) system, for scanning an object. The SLM system performs test scans of the object to acquire a plurality of sets of measurements of the object, wherein a different value is used for the parameter for each test scan. For each test scan, a value of a quality metric is calculated, based on the set of measurements of the object associated with the test scan and simulation data representing a simulated scan of the object by the SLM system. A test scan is then identified that has a quality metric value that satisfies a specified optimization criterion; and a value of the adjustable parameter that was used for the identified test scan is selected as the optimal value of the adjustable parameter, for scanning the object. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/104198 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) Original (OR) Class G01N 2021/1734 (20130101) G01N 2021/1757 (20130101) G01N 2021/1785 (20130101) G01N 2201/11 (20130101) G01N 2201/0675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255699 | Blumenthal et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Massachusetts Institute of Technology (Cambridge, Massachusetts); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Massachusetts Institute of Technology (Cambridge, Massachusetts); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Daniel J. Blumenthal (Santa Barbara, California); Matt Eichenfield (Albuquerque, New Mexico); Dirk Englund (Cambridge, Massachusetts); Mikkel Heuck (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for hybrid integration of ultra-low loss waveguide photonic circuits with various efficient on-chip elements are described. The photonic circuits can integrate various elements including (but not limited to): gain, modulation, detection, and nonlinear optical elements. The integrated photonic chips can be manufactured in a flexible, reconfigurable, 3D heterogeneous platform. The integrated photonic chips can cover wavelength ranges from the visible wavelength to infrared wavelength. |
| FILED | Thursday, December 21, 2023 |
| APPL NO | 18/393392 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/1228 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240256742 | Owen et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven J. Owen (Carlsbad, California); Armida J. Carbajal (Albuquerque, New Mexico); Corey Devan Ernst (American Fork, Utah); Matthew Gregor Peterson (Albuquerque, New Mexico) |
| ABSTRACT | A computer-implemented method of machine learning classification for Computer Assisted Design (CAD) is provided. The method comprises receiving a number of CAD volumes comprising a dataset, wherein each CAD volume is characterized by a number of scalar values corresponding to features of the CAD volume, wherein the features rely on geometry queries from a CAD kernel. Each CAD volume is labeled with part names according to a set of categories defined by a user, and a machine learning model is trained with the features of the labeled CAD volumes. |
| FILED | Tuesday, October 10, 2023 |
| APPL NO | 18/484143 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/10 (20200101) G06F 30/27 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240256868 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dan Wang (Berkeley, California); Qiang Du (Pleasanton, California); Russell Wilcox (Berkeley, California); Tong Zhou (Albany, California); Christos Bakalis (Berkeley, California); Derun Li (Concord, California) |
| ABSTRACT | A machine learning (ML) controller and method for systems that can learn to stabilize them based on measurements of an unstable system. This allows for training on a system not yet controlled and for continuous learning as the stabilizer operates. The controller has improved performance on unstable systems compared to similar technologies, especially complex ones with many inputs and outputs. Furthermore, there is no need for modelling the physics, and the controller can adapt to un-analyzed or partially analyzed systems. |
| FILED | Monday, March 18, 2024 |
| APPL NO | 18/607954 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257996 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qigui Wang (Rochester Hills, Michigan); John S. Agapiou (Rochester Hills, Michigan); Liang Wang (Rochester Hills, Michigan); Lei Hao (Troy, Michigan) |
| ABSTRACT | A method of making an electric conductor having a conductive skin layer. The method comprises providing a conductive member having a first width and a conductive layer disposed thereon for conductivity. The conductive layer has a second width to define a width ratio of the first width to the second width of 4:1 to 200:1. The conductive layer has greater conductivity than the conductive member. The method comprises disposing the conductive layer about the conductive member to define a conductive layered member and pressing the conductive layered member for mechanical contact to define a pressed layered member. The method comprises thermally treating the pressed layered member for diffusion between the conductive layer and the conductive member defining a diffused layered member. The method further comprises cooling the diffused layered member for diffusion bonding free of an intermetallic phase between the conductive layer and the conductive member. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/161496 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/023 (20130101) B23K 2101/38 (20180801) B23K 2103/10 (20180801) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 5/02 (20130101) H01B 13/0016 (20130101) H01B 13/0036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258400 | Timpson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik Joseph Timpson (Lee’s Summit, Missouri); Justin M. Schlitzer (Stillwell, Kansas); Thomas Matthew Selter (Blue Springs, Missouri); Michael Walsh (Overland Park, Kansas) |
| ABSTRACT | Systems and methods for building passive and active electronics with diamond-like carbon (DLC) coatings are provided herein. DLC may be layered upon substrates to form various components of electronic devices. Passive components such as resistors, capacitors, and inductors may be built using DLC as a dielectric or as an insulating layer. Active components such as diodes and transistors may be built with the DLC acting substantially like a semiconductor. The amount of sp2and sp3 bonded carbon atoms may be varied to modify the properties of the DLC for various electronic components. |
| FILED | Monday, March 11, 2024 |
| APPL NO | 18/601289 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/51 (20130101) Original (OR) Class H01L 29/84 (20130101) H01L 29/868 (20130101) H01L 29/4916 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258440 | Tao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yuguo Tao (Atlanta, Georgia); Anna S. Erickson (Atlanta, Georgia) |
| ABSTRACT | An exemplary embodiment of the present disclosure provides a photomultiplier, comprising a silicon substrate, a first antireflective layer, and a second antireflective layer. The silicon substrate can have a top surface. The first anti-reflective layer can be disposed on the top surface of the silicon substrate. The second anti-reflective layer can be disposed on top of the first anti-reflective layer. |
| FILED | Tuesday, January 09, 2024 |
| APPL NO | 18/408102 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/107 (20130101) H01L 31/02161 (20130101) Original (OR) Class H01L 31/02366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258447 | Frye et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clint Frye (Oakland, California); Sara E. Harrison (Livermore, California); Joel Basile Varley (San Francisco, California); Lars F. Voss (Livermore, California); Jani Jesenovec (Pullman, Washington); Benjamin Dutton (Pullman, Washington); Dylan Evans (Livermore, California); John S. McCloy (Pullman, Washington) |
| ABSTRACT | Various devices, systems and methods such as photonductive semiconductor switches (PCSS) and optically addressable light valves (OALVs) include a photoconducting β-Ga2O3 layer having a transition metal (TM) doped region formed by diffusion of transition metal into a β-Ga2O3 substrate. The diffusion of the TM into the β-Ga2O3 substrate provides for the controlled concentration and thickness of the doped TM region that is integrated into the bulk β-Ga2O3 substrate. |
| FILED | Monday, January 29, 2024 |
| APPL NO | 18/426083 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/133362 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/0321 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258458 | FRANCE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan Matthew FRANCE (Golden, Colorado); Kirstin ALBERI (Denver, Colorado) |
| ABSTRACT | The present disclosure relates to a device that includes a first stack and a second stack, with each stack including, in order: an n-type cladding layer constructed of an alloy selected from at least one of GaInP, AlGaAs, GaInAsP, and/or AlGaInP, an n-type outer barrier layer constructed of at least one of GaAs and/or GaP; at least one quantum well; a p-type outer barrier layer constructed of at least one GaAs or GaP; and a p-type cladding layer constructed an alloy selected from at least one of GaInP, AlGaAs, GaInAsP, and/or AlGaInP; and a tunnel junction. |
| FILED | Monday, January 08, 2024 |
| APPL NO | 18/406697 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/0753 (20130101) H01L 33/06 (20130101) Original (OR) Class H01L 33/0008 (20130101) H01L 33/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258510 | BORENSTEIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles David BORENSTEIN (College Station, Texas); James David PARAMORE (Bryan, Texas); Karl Theodore HARTWIG (Colleg Station, Texas); Brady Glenn BUTLER (College Station, Texas); Michael Jan DEMKOWICZ (College Station, Texas) |
| ABSTRACT | Described herein are composites, including metal-metal composites and liquid-solid composites, that exhibit improved properties. Also provided are methods of making and using these composites. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424062 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) Original (OR) Class H01M 10/399 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258515 | Ceder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Gerbrand Ceder (Berkeley, California); Jianping Huang (Berkeley, California) |
| ABSTRACT | A lithium rich partially cation disordered transition metal oxide cathode material is provided that exhibits reduced voltage hysteresis, reduced or inhibited transition metal migration and increased capacity and energy storage compared with layered oxides. The lithium rich cathode material is based on Li1+xCr1−x-yMyO2 where M is a transition metal with limited redox activity, such as Mn4+, Ti4+, Zr4+, Sn4+, Nb5+, Ta5+, and W6+, and where 0<x<0.33 and 0<y<0.67. Cation disordering is induced in the material that alters both the structure and the electrochemistry and effectively mitigate voltage hysteresis and increase the reversibility of the Cr3+/Cr6+ redox couple and the energy capacity. Lithium transport in the cation-disordered structure occurs through a percolation network of Li-rich tetrahedral environments. |
| FILED | Monday, February 26, 2024 |
| APPL NO | 18/587049 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 31/006 (20130101) C01G 45/1228 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/20 (20130101) C01P 2002/50 (20130101) C01P 2002/72 (20130101) C01P 2002/77 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) Original (OR) Class H01M 4/623 (20130101) H01M 4/625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258831 | PRIES et al. |
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| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jason L. PRIES (Oak Ridge, Tennessee); Veda Prakash GALIGEKERE (Oak Ridge, Tennessee); Gui-Jia SU (Oak Ridge, Tennessee) |
| ABSTRACT | Polyphase wireless power transfer systems are provided. The transfer system may be used for charging hybrid and electric vehicles. The systems are capable of transferring over 50 KW over an air gap of 15 cm. The systems use a rotating magnetic field to transfer power. The system may comprise transmitter coil assembly. The coil assembly may be one or more layers. The system may employ either unipolar or bipolar coils. The transmitter also comprises compensating capacitance connected in series with at least one coil for each phase. A value of the compensating capacitance for each phase is determined such that the transmitter has at least two independently excitable resonant modes at a resonant frequency. The transmitter is compatible with a plurality of different receivers including three-phase, single phase with a circular coil and single phase with DD coils. |
| FILED | Monday, March 18, 2024 |
| APPL NO | 18/608323 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/38 (20130101) H01F 38/14 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258851 | Tangudu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RTX CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jagadeesh K. Tangudu (South Windsor, Connecticut); Andrzej E. Kuczek (Bristol, Connecticut); Joseph E. Turney (Amston, Connecticut); Abbas A. Alahyari (Glastonbury, Connecticut); Kimberly R. Saviers (Glastonbury, Connecticut); Dmytro M. Voytovych (Rocky Hill, Connecticut) |
| ABSTRACT | Aircraft may include electric motors. The aircraft electric motors may include a rotor assembly comprises an outer diameter portion, and inner diameter portion, and an end portion, arranged to define a stator cavity, and a rotor hub configured to connect to a shaft of the aircraft electric machine, a stator assembly arranged within the stator cavity, and at least one fan assembly arranged in the rotor assembly and configured to induce a cooling flow through the stator cavity. |
| FILED | Wednesday, February 01, 2023 |
| APPL NO | 18/162848 |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/30 (20240101) Dynamo-electric Machines H02K 1/16 (20130101) H02K 1/32 (20130101) H02K 1/2786 (20130101) Original (OR) Class H02K 9/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258914 | Dwari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Suman Dwari (East Hartford, Connecticut); W. Warren Chen (Glastonbury, Connecticut); Lei Xing (South Windsor, Connecticut) |
| ABSTRACT | A system can include a bi-directional converter circuit comprising a plurality of switches and at least one flying capacitor. One or more the plurality of switches can experience overvoltage in a fault state. The system can include a control module operatively connected to the plurality of switches to control a state of the plurality of switches. The control module can be configured to receive a sense signal indicative of flying capacitor voltage and to control the one or more switches of the plurality of switches to turn on or remain on to prevent switch overvoltage of the one or more switches if the flying capacitor voltage is outside of a normal range. |
| FILED | Thursday, January 26, 2023 |
| APPL NO | 18/102010 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 1/32 (20130101) H02M 3/157 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240259301 | Bataineh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abdulla M. Bataineh (Vista, California); Thomas L. Court (Three Lakes, Wisconsin); Edwin L. Froese (Burnaby, Canada) |
| ABSTRACT | Systems and methods are provided for efficiently routing data through a network having a plurality of switches configured in a fat-tree topology, including: receiving a data transmission comprising a plurality of packets at an edge port of the network, and routing the data transmission through the network with routing decisions based upon a routing table, wherein the routing table includes entries to effect routing decisions based upon a destination based hash function. |
| FILED | Tuesday, April 09, 2024 |
| APPL NO | 18/630121 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/28 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/02 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240259302 | Froese |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edwin L. Froese (Burnaby, Canada) |
| ABSTRACT | Systems and methods are provided for managing a data communication within a multi-level network having a plurality of switches organized as groups, with each group coupled to all other groups via global links, including: at each switch within the network, maintaining a global fault table identifying the links which lead only to faulty global paths, and when the data communication is received at a port of a switch, determine a destination for the data communication and, route the communication across the network using the global fault table to avoid selecting a port within the switch that would result in the communication arriving at a point in the network where its only path forward is across a global link that is faulty; wherein the global fault table is used for both a global minimal routing methodology and a global non-minimal routing methodology. |
| FILED | Wednesday, April 10, 2024 |
| APPL NO | 18/631217 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/28 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/02 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240259663 | Sugg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vega Wave Systems, Inc. (WEST CHICAGO, Illinois) |
| ASSIGNEE(S) | Vega Wave Systems, Inc. (WEST CHICAGO, Illinois) |
| INVENTOR(S) | Alan Sugg (NAPERVILLE, Illinois); Anthony Moretti (Saint Charles, Illinois) |
| ABSTRACT | Articles of manufacture, machines, processes for using the articles and machines, processes for making the articles and machines, and products produced by the process of making, along with necessary intermediates, directed to a scanning camera system. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 18/288923 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4298 (20130101) G02B 26/105 (20130101) Pictorial Communication, e.g Television H04N 23/555 (20230101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240259706 | Gutierrez Barragan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Felipe Gutierrez Barragan (Alameda, California); Yuhao Liu (Madison, Wisconsin); Atul Ingle (Madison, Wisconsin); Mohit Gupta (Madison, Wisconsin); Andreas Velten (Madison, Wisconsin) |
| ABSTRACT | In accordance with some embodiments, systems, methods, and media for high dynamic range imaging using single-photon and conventional image sensor data are provided. In some embodiments, the system comprises: first detectors configured to detect a level of photons proportional to incident photon flux; second detectors configured to detect arrival of individual photons; a processor programmed to: receive, from the first detectors, first values indicative of photon flux from a scene with a first resolution; receive, from the second detectors, second values indicative of photon flux from the scene with a lower resolution; provide a first encoder of a trained machine learning model first flux values based on the first values, provide the second encoder of the model second flux values; receive, as output, values indicative of photon flux from the scene; and generate a high dynamic range image based on the third plurality of values. |
| FILED | Monday, September 11, 2023 |
| APPL NO | 18/464987 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14634 (20130101) H01L 27/14645 (20130101) Pictorial Communication, e.g Television H04N 25/585 (20230101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240260166 | JIANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Omega-P R and D, Inc. (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yong JIANG (New Haven, Connecticut); Jay L. HIRSHFIELD (Orange, Connecticut) |
| ABSTRACT | Apparatuses and methods for accelerating electrons include an electron source configured to provide a beam of electrons and an accelerator that utilizes electron cyclotron resonance acceleration (eCRA). The accelerator includes a radio frequency (RF) cavity having a longitudinal axis, one or more inlets, and one or more outlets and a first electro-magnet substantially surrounding at least a portion of the cavity and configured to produce an axial magnetic field. The RF cavity is coupled to an RF source and configured to accelerate the beam of electrons axially entering the RF cavity with non-linear cyclotron resonance acceleration. A second electro-magnet located downstream of the one or more outlets of the RF cavity is configured to generate an inverse cusp in the axial magnetic field to manipulate the beam of electrons leaving the RF cavity from a helical orbit to a substantially linear path. |
| FILED | Wednesday, January 31, 2024 |
| APPL NO | 18/428788 |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/00 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/02 (20130101) H05H 7/04 (20130101) Original (OR) Class H05H 13/005 (20130101) H05H 2007/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240260482 | Dynes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Dynes (La Jolla, California); Uday Goteti (San Diego, California) |
| ABSTRACT | Methods, systems, and devices for neural networks and neuromorphic computing are disclosed. In one implementation, a neural network includes an array of superconducting loops to store information, the superconducting loops multiply coupled to each other inductively or through Josephson junctions linking the superconducting loops, one or more input channels coupled to the array of superconducting loops to carry spiking input voltage signals to the array of superconducting loops, and one or more output channels coupled to the array of superconducting loops to carry spiking output voltage signals from the array of superconducting loops. |
| FILED | Thursday, July 28, 2022 |
| APPL NO | 18/293167 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/063 (20130101) G06N 10/40 (20220101) Electric solid-state devices not otherwise provided for H10N 60/12 (20230201) Original (OR) Class H10N 60/805 (20230201) H10N 69/00 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240252264 | Palmowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph Palmowski (Pasadena, California); Shane Farritor (Lincoln, Nebraska) |
| ABSTRACT | Disclosed herein are various robotic surgical devices and systems that include first and second elongate bodies, first and second driveshafts disposed through the second elongate body, and an in-line shoulder joint with a robotic arm coupled thereto. In certain implementations, the in-line shoulder joint has a differential yoke and a dual shaft disposed within the yoke lumen. |
| FILED | Monday, March 18, 2024 |
| APPL NO | 18/607863 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 2034/305 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/102 (20130101) B25J 9/126 (20130101) B25J 17/0258 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252583 | RUFF |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Creative Bio-Peptides, Inc. (Potomac, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael RUFF (Potomac, Maryland) |
| ABSTRACT | Disclosed herein are polypeptides, derivatives thereof, and salts thereof, as well as pharmaceutical compositions containing these, useful alone or in combination with other therapies for treating weight loss, weight gain, or to maintain a healthy body weight in a subject. Also disclose herein are the use of the peptides disclosed herein for treating stress, depression, anxiety, and pain catastrophizing. In some cases, the subject can be suffering from persistent postsurgical pain. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 18/560768 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 25/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252688 | Khandhar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HDT Bio Corp. (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amit Praful Khandhar (Issaquah, Washington); Bryan Berube (Issaquah, Washington); Kyle Krieger (Seattle, Washington); Jesse Hong-Sae Erasmus (Port Orchard, Washington); Gaurav Gulati (Shoreline, Washington); Adrian Simpson (Shoreline, Washington) |
| ABSTRACT | The disclosure provides nanoparticle and compound compositions and methods of making and using the same to deliver a bioactive agent such as a nucleic acid encoding a protein, antibody, antigen, expression enhancer, or functional fragment thereof to a subject. Various nanoparticle carriers are described. Various compounds that increase protein expression are described. Various nucleic acids coding expression enhancers that increase protein expression are described. In some instances, the nanoparticle component may include a hydrophobic core, optionally having an inorganic particle, and a membrane having a cationic lipid. |
| FILED | Thursday, March 21, 2024 |
| APPL NO | 18/612003 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5115 (20130101) A61K 9/5123 (20130101) A61K 9/5176 (20130101) A61K 38/45 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 48/0033 (20130101) A61K 48/0066 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253096 | Heintz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Amy M. Heintz (Dublin, Ohio); Jacob Lilly (Columbus, Ohio); Christopher Buurma (Gahanna, Ohio); Ryan W. Daly (Columbus, Ohio) |
| ABSTRACT | Apparatus, systems (including solvent or enzyme), and methods of degrading plastic are described. Plastic waste is stretched in the presence of solvent. The surface may be further treated to increase hydrophilicity. The resulting plastics can be treated with plastic-degrading enzyme either with microorganisms or direct application of enzyme. |
| FILED | Tuesday, May 24, 2022 |
| APPL NO | 18/563429 |
| CURRENT CPC | Crushing, Pulverising, or Disintegrating in General; Milling Grain B02C 18/2283 (20130101) B02C 23/06 (20130101) Disposal of Solid Waste B09B 3/35 (20220101) Original (OR) Class B09B 3/60 (20220101) B09B 3/70 (20220101) B09B 2101/75 (20220101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/08 (20130101) C08J 11/105 (20130101) C08J 2367/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253717 | Burguess et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Victor Wilhelm Burguess (Royal Oak, Michigan); Frederick Carl Rickert, II (Royal Oak, Michigan) |
| ABSTRACT | A method of installing an underbody kit to a vehicle comprising providing a rapid underbody kit deployment crate comprising a pallet, at least one inflatable bladder, and at least one cover; removing the at least one cover from the pallet; placing the underbody kit onto the pallet and the at least one inflatable bladder; securing the at least one cover back onto the pallet; transporting the rapid underbody kit deployment crate to an assembly location; removing the at least one cover from the pallet; driving the vehicle over the rapid underbody kit deployment crate; inflating the at least one inflatable bladder to vertically lift the underbody kit into installation position; installing the underbody kit to an underbody of the vehicle; deflating the at least one inflatable bladder by releasing the fluid from the at least one inflatable bladder; and driving the vehicle away from the rapid underbody kit deployment crate. |
| FILED | Wednesday, April 10, 2024 |
| APPL NO | 18/631313 |
| CURRENT CPC | Motor Vehicles; Trailers B62D 21/155 (20130101) B62D 25/2072 (20130101) B62D 65/024 (20130101) Original (OR) Class Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load B66F 3/35 (20130101) B66F 3/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253957 | Silbert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Maritime Applied Physics Corporation (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Wade Silbert (Columbia, Maryland); James Nathaniel Chafe (Annapolis, Maryland) |
| ABSTRACT | A vehicle comprising a first device and a canopy. The first device includes a first spool device; a first drive screw comprising a threaded portion, wherein the first drive screw is configured to extend through an opening in the first spool device; a first drive motor coupled to the first drive screw, wherein the first drive motor is configured to rotate the first drive screw; a first tension controller device coupled to the first spool device; and a first stop pawl coupled to the first drive screw. The canopy includes a canopy fabric; and a first line, wherein the canopy is coupled to the first spool device through the first line. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/103397 |
| CURRENT CPC | Capstans; Winches; Tackles, e.g Pulley Blocks; Hoists B66D 1/12 (20130101) B66D 1/39 (20130101) B66D 1/50 (20130101) Original (OR) Class Buildings or Like Structures for Particular Purposes; Swimming or Splash Baths or Pools; Masts; Fencing; Tents or Canopies, in General E04H 15/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254169 | SHIKUMA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | San Diego State University (SDSU) Foundation, dba San Diego State University Research Foundation (San Diego, California); J. CRAIG VENTER INSTITUTE (La Jolla, California); ETH ZURICH (Zurich, Switzerland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas J. SHIKUMA (San Diego, California); Sinem BEYHAN (La Jolla, California); Martin PILHOFER (Zurich, Switzerland); Charles ERICSON (Zurich, Switzerland) |
| ABSTRACT | Provided are compositions, kits, and methods for delivering a proteinaceous cargo, or a protein or a peptide, or a drug or a marker, to or into a cell or to an individual in need thereof. Methods comprise use of: a substantially purified or isolated bacterial Contractile Injection Systems (CIS) or Metamorphosis Associated Contractile structure; a recombinant bacterial Contractile Injection Systems (CIS) or Metamorphosis Associated Contractile structure (MACs); a liposome or lipid-comprising nanoparticle incorporating or expressing on its outer surface the substantially purified or isolated bacterial CIS or MACs, or the recombinant bacterial CIS or MACs; a protoplast or a spheroplast incorporating or expressing on its outer surface the substantially purified or isolated bacterial CIS or MACs, or the recombinant bacterial CIS or MACs; a cell expressing on its extracellular surface the substantially purified or isolated bacterial CIS or MACs, or the recombinant bacterial CIS or MACs. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 17/294656 |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Original (OR) Class C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254190 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| INVENTOR(S) | Sanghyun Kim (Rockville, Maryland); Nikolaos Zacharakis (Gaithersburg, Maryland); Steven A. Rosenberg (Potomac, Maryland); Frank J. Lowery, III (Clarksburg, Maryland); Maria R. Parkhurst (Ellicott City, Maryland) |
| ABSTRACT | Disclosed are isolated or purified T cell receptors (TCRs) having antigenic specificity for human p53C135Y, human p53R175H, or human p53M237I. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 18/289596 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) A61K 39/4632 (20230501) A61K 39/464451 (20230501) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254477 | Devaraj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neal Devaraj (La Jolla, California); Dongyang Zhang (La Jolla, California) |
| ABSTRACT | Provided herein are, inter alia, methods and compositions for linking RNA stem loops. The methods include linking a first RNA stem loop and a second RNA stem loop by way of a preQ1 linking compound. |
| FILED | Tuesday, November 23, 2021 |
| APPL NO | 18/038190 |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1077 (20130101) C12N 15/11 (20130101) Original (OR) Class Enzymes C12Y 204/02029 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254507 | Veiseh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Omid Veiseh (Bellaire, Texas); Jacob Robinson (Houston, Texas); Jonathan Rivnay (Chicago, Illinois); Isaac Hilton (Houston, Texas); Samantha T. Fleury (Houston, Texas); Matthew C. Parker (Houston, Texas); Jacob H. Goell (Houston, Texas); Jing Li (Houston, Texas); Kaiyuan Wang (Houston, Texas) |
| ABSTRACT | An engineered cell expressing a therapeutic agent and a reporter agent, the engineered cell comprising a first transgene containing a light sensing DNA sequence encoding a light sensing protein, and a second transgene containing a calcium activated promoter, a therapeutic agent DNA encoding a therapeutic agent, and a reporter agent DNA encoding a reporter agent. |
| FILED | Thursday, April 21, 2022 |
| APPL NO | 18/287709 |
| CURRENT CPC | Peptides C07K 14/435 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/50 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2830/001 (20130101) Enzymes C12Y 304/22062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254531 | Breger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joyce C. Breger (Washington, District of Columbia); Kimihiro Susumu (Washington, District of Columbia); Igor L. Medintz (Springfield, Virginia); Gregory A. Ellis (Washington, District of Columbia); Sebastian A. Diaz (Washington, District of Columbia); Shelby L. Hooe (Washington, District of Columbia) |
| ABSTRACT | Enzyme cascade reactions, wherein the product of a first enzyme is the substrate of a second enzyme and so forth, were found to be enhanced by the presence of peptides. It is believed that the peptides operate by forming coacervates, which are membrane-less compartments where, in the case of coacervates formed by peptides, the liquid-liquid phase separation involves water as the continuous phase both inside and outside the coacervate. |
| FILED | Monday, January 29, 2024 |
| APPL NO | 18/425004 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 9/88 (20130101) C12N 9/1217 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/32 (20130101) Original (OR) Class Enzymes C12Y 102/01011 (20130101) C12Y 207/02004 (20130101) C12Y 403/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254571 | Leski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tomasz A. Leski (Falls Church, Virginia); Joseph R. Spangler (La Plata, Maryland); Zheng Wang (Burke, Virginia); Scott N. Dean (Bowie, Maryland); David A. Stenger (Annapolis, Maryland) |
| ABSTRACT | A technique for the design of minimum CRISPR RNA (crRNA) sets aids in the detection of diverse nucleic acid targets using sequence degeneracy. As a working example, candidate degenerate Cas13a crRNA sets were designed for detection of diverse RNA targets (Lassa virus). A decision tree machine learning (ML) algorithm (RuleFit) was applied to define the top attributes that determine the specificity of degenerate crRNAs to elicit collateral nuclease activity. This general ML approach can be applied to the design of degenerate crRNA sets for any CRISPR/Cas system. |
| FILED | Thursday, January 25, 2024 |
| APPL NO | 18/422206 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2320/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255042 | BABUSKA et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Pavel BABUSKA (El Segundo, California); Vinay K. GOYAL (El Segundo, California) |
| ABSTRACT | An open socket joint configured to prevent zinc creep includes a retaining mesh that sits on a lip of an outer shell casing of the open socket joint. The retaining mesh is configured to prevent zinc within the open socket joint to extrude. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/161345 |
| CURRENT CPC | Belts, Cables, or Ropes, Predominantly Used for Driving Purposes; Chains; Fittings Predominantly Used Therefor F16G 11/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255191 | Ferrara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Peter J. Ferrara (Westampton, New Jersey); Jacob T. Kephart (Garnet Valley, Pennsylvania); Avi Friedman (Bethesda, Maryland) |
| ABSTRACT | A pneumatic cryocooler using a pneumatic motor for use in cryogenically cooling superconductors, which pneumatic cryocooler is capable of operation in strong magnetic fields. |
| FILED | Thursday, January 18, 2024 |
| APPL NO | 18/415721 |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 9/14 (20130101) Original (OR) Class F25B 2309/003 (20130101) F25B 2309/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255315 | Couriol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthieu Couriol (Salt Lake City, Utah); Pierre-Emmanuel Gaillardon (Salt Lake City, Utah) |
| ABSTRACT | A sensor interface for a resistive sensor has an analog front end comprising. The analog front end has an analog input/output (I/O) sensor port to be coupled to the resistive sensor. An integration stage is coupled to the analog I/O sensor port to oscillate at an oscillation frequency proportional to a sensor resistance of the resistive sensor. The integration stage has a variable integrator capacitance to vary the oscillation frequency. A gain stage is coupled to the integration stage and has a variable gain to vary the oscillation frequency of the integration stage. The sensor interface also has a smart digital controller (SDC) coupled to the analog front end to compute the sensor resistance of the resistive sensor based on the oscillation frequency. In addition, the SDC automatically detects unstable oscillation in the integration stage and causes the variable gain and the variable integrator capacitance to change. |
| FILED | Thursday, January 26, 2023 |
| APPL NO | 18/159895 |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255424 | Tehrani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kayvan Forouhesh Tehrani (Urbana, Illinois); Alejandro De La Cadena (Urbana, Illinois); Stephen A. Boppart (Champaign, Illinois) |
| ABSTRACT | Systems and methods of microscopy include and/or apply a laser light source configured to produce an excitation light; a modulator configured to modulate the excitation light to produce a modulated light; a pulse compressor configured to compress a pulse of the modulated light to produce a pre-compensated light; a beam scanner configured to raster scan the pre-compensated light on a sample; a detector configured to receive a light signal from the sample and produce a detection signal; and a lock-in amplifier configured to receive the detection signal and perform an electronic heterodyne amplification of the detection signal. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424224 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/636 (20130101) Original (OR) Class G01N 2201/12 (20130101) Amplifiers H03F 3/08 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255483 | ROSENSTEIN et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob K. ROSENSTEIN (Providence, Rhode Island); Christopher ROSE (Providence, Rhode Island) |
| ABSTRACT | A system includes an array of chemical, pressure, and temperature sensors, and a temporal airflow modulator configured to provide sniffed vapors in a temporally-modulated sequence through a plurality of different air paths across multiple sensor locations. |
| FILED | Friday, October 20, 2023 |
| APPL NO | 18/490881 |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0018 (20130101) B81B 2201/0264 (20130101) B81B 2201/0278 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0075 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255604 | SHEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan SHEN (Germantown, Maryland); Genshe CHEN (Germantown, Maryland); Khanh PHAM (Kirtland AFB, New Mexico) |
| ABSTRACT | The present disclosure provides a cross-correlation based method, a system and a storage medium for blind electromagnetic interference Doppler estimation from a single satellite geolocation system. The method includes at a first time, calculating a power spectral density (PSD) of a received signal; smoothing the PSD of the received signal using moving window average, and saving the smoothed PSD of the received signal as PSD0; at a next time, calculating a PSD of another received signal; smoothing the PSD of the another received signal using moving window average, and saving the smoothed PSD of the another received signal as PSD1; performing cross correlation between PSD0 and PSD1 to obtain a cross-correlation result; determining a peak position from the cross-correlation result; and obtaining a Doppler estimation based on a peak position shift between the peak position and a reference position. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/161014 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0246 (20200501) Original (OR) Class G01S 5/0294 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255751 | Blumenthal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); United States Army (Adelphi, Maryland) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); United States Army (Adelphi, Maryland) |
| INVENTOR(S) | Daniel J. Blumenthal (Santa Barbara, California); Jiawei Wang (Goleta, California); Kaikai Liu (Santa Barbara, California); Ryan Q. Rudy (Adelphi, Maryland) |
| ABSTRACT | Disclosed herein is a stress optical modulator. The modulator include a circular piezo-electric actuator; and a ring waveguide separated from the circular piezo-electric actuator by a top cladding layer. The circular piezo-electric actuator may be offset from the ring waveguide such that a first circular portion of the circular piezo-electric actuator is located on the outside of the ring waveguide and a second circular portion of the circular piezo-electric actuator is located on the inside of the ring waveguide. The circular piezo-electric actuator may be configured to change the guiding properties of the ring waveguide based on the voltage applied to the circular piezo-electric actuator by inducing strain through the top cladding layer to change the optical properties of the ring waveguide. |
| FILED | Wednesday, October 11, 2023 |
| APPL NO | 18/485173 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4204 (20130101) G02B 26/0875 (20130101) Original (OR) Class Electric solid-state devices not otherwise provided for H10N 30/206 (20230201) H10N 30/877 (20230201) H10N 30/8554 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255768 | Puckett et al. |
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| FUNDED BY |
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| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Matthew Wade Puckett (Phoenix, Arizona); Chad Fertig (Roseville, Minnesota); Chad Hoyt (Roseville, Minnesota); Karl D. Nelson (Plymouth, Minnesota); Luke Horstman (Saint Louis Park, Minnesota) |
| ABSTRACT | An optical device comprises a substrate layer having an upper surface, and a waveguide layer over the upper surface of the substrate layer. The waveguide layer comprises an input waveguide defined by a first waveguide portion having a first refractive index; an input slab defined by the first waveguide portion, the input slab adjoined with the input waveguide; and a microlens array defined by a second waveguide portion having a second refractive index that is different from the first refractive index. The microlens array is in optical communication with the input waveguide through the input slab. The microlens array is configured to receive a diverging planar light beam from the input slab along a direction of propagation. The microlens array is configured to control a far-field emission of the light beam such that an emission profile of the light beam exhibits a substantially uniform intensity. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/162558 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0927 (20130101) G02B 27/0961 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240256283 | Fryman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Joshua B. Fryman (Corvallis, Oregon); Byoungchan Oh (Portland, Oregon); Sai Dheeraj Polagani (Hillsboro, Oregon); Kevin P. Ma (Beaverton, Oregon); Robert S. Pawlowski (Beaverton, Oregon); Bharadwaj Coimbatore Krishnamurthy (Hillsboro, Oregon); Shruti Sharma (Hillsboro, Oregon); Smitha P. Vasantha Kumar (Hillsboro, Oregon); Jason Howard (Portland, Oregon); Daniel S. Klowden (Portland, Oregon) |
| ABSTRACT | A system is provided that includes a set of graph processing cores and a set of dense compute cores. where the set of graph processing cores and the set of dense cores are interconnected in a network. The dense compute cores include offload queue circuitry to receive an offload request from the set of graph processing cores to handle dense compute workloads. Memory controllers are also provided in the system for use by the graph processing cores in reading and writing to memory in association with sparse graph applications. the memory controllers enhanced to efficiently handle memory transactions in sparse graph applications. |
| FILED | Thursday, March 31, 2022 |
| APPL NO | 18/566068 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/3851 (20130101) Original (OR) Class G06F 11/3409 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240256734 | SHEN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dan SHEN (Germantown, Maryland); Genshe CHEN (Germantown, Maryland); Khanh PHAM (Kirtland AFB, New Mexico); Erik BLASCH (Arlington, Virginia) |
| ABSTRACT | The present disclosure provides a method for decentralized optimal control for passive SSG of ground-based EMI sources. The method includes simulating a scenario based on an EMI source and a satellite specified by a TLE file; and calculating positions, velocities and accelerations of the satellite at different time indexes of the simulated scenario; calculating Doppler shifts and Doppler rates according to the positions, the velocities and the accelerations of the satellite at the different time indexes; and implementing a constrained unscented Kalman filter (cUKF) based on the Doppler shifts and the Doppler rates to obtain an updated state; and calculating a recursive constrained posterior Cramér-Rao bound (rcPCRB); and fine tuning the cUKF using the calculated rcPCRB to obtain an updated cUKF. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/160717 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) Original (OR) Class G06F 2111/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240256858 | YEH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chih-hung YEH (Alameda, California); Pedro Daniel BARBOSA SEQUEIRA (Palo Alto, California); Melinda T. GERVASIO (Mountain View, California); Jesse Albert HOSTETLER (Boulder, Colorado) |
| ABSTRACT | In general, techniques are described for generating counterfactuals using a machine learning system that implements a generative model. In an example, a method includes receiving, by a trained generative machine learning model, an input query, wherein the generative machine learning model is trained by jointly encoding a plurality of input observations and a plurality of outcome variables based on the plurality of input observations; generating, by the trained generative machine learning model, latent representation of the input query; and transforming, by the trained generative machine learning system, the latent representation of the input query to generate a counterfactual related to the received input query, wherein the generated counterfactual meets a predefined outcome criteria. |
| FILED | Thursday, December 21, 2023 |
| APPL NO | 18/393182 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/0475 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257793 | Scanlon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army DEVCOM, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael V. Scanlon (Laurel, Maryland) |
| ABSTRACT | Metamaterials that may reduce or modify the spectrum of acoustic energy or power (and/or other types of fluid energy or power) via an array of circulation elements, such as vortex diodes are described. Circulation elements may be arranged in various types of arrays (e.g., serial, parallel, etc.) that may be able to form various differently shaped metamaterial elements (e.g., sheets, boxes, tubes, etc.) appropriate for various different applications. |
| FILED | Thursday, September 14, 2023 |
| APPL NO | 18/368056 |
| CURRENT CPC | Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/04 (20130101) G10K 11/162 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257801 | LUBIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey LUBIN (Princeton, New Jersey); Alexander ERDMANN (Malvern, Ohio); James BERGEN (Pennington, New Jersey); Harry BRATT (Mountain View, California); Jihua HUANG (Santa Clara, California); Sarah BAKST (San Francisco, California); Michael LOMNITZ (Castro Valley, California); Zachary DANIELS (Robbinsville, New Jersey); John CADIGAN (San Diego, California); Ali CHAUDHRY (Princeton Junction, New Jersey); Zhiwei ZHU (Princeton, New Jersey); Joshua CHATTIN (Mount Laurel, New Jersey); Girish ACHARYA (Redwood City, California) |
| ABSTRACT | A method, apparatus, and system for creating a script for rendering audio and/or video streams include identifying at least one prosodic speech feature in a received audio stream and/or a received language model, creating a respective prosodic speech symbol for each of the at least one identified prosodic speech features, converting the received audio stream and/or the received language model into a text stream, temporally inserting the created at least one prosodic speech symbol into the text stream, identifying in a received video stream at least one prosodic gesture of at least a portion of a body of a speaker of the received audio stream, creating at least one respective gesture symbol for each of the at least one identified prosodic gestures, and temporally inserting the created at least one gesture symbol into the text stream along with the at least one prosodic speech symbol to create a prosodic script. |
| FILED | Thursday, December 21, 2023 |
| APPL NO | 18/393575 |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/02 (20130101) G10L 15/25 (20130101) G10L 15/063 (20130101) G10L 15/183 (20130101) G10L 15/1807 (20130101) Original (OR) Class G10L 25/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257909 | Iyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| INVENTOR(S) | Shilpa Iyer (Springdale, Arkansas); Raj R. Rao (Springdale, Arkansas); Shilpi Agrawal (Fayetteville, Arkansas) |
| ABSTRACT | Embodiments of the present disclosure pertain to methods of assessing one or more mitochondrial or metabolic disorders in a subject by receiving one or more measured biomarker levels of the subject and correlating differentially expressed levels of the one or more measured biomarkers to one or more mitochondrial or metabolic disorders in the subject. Such methods may also include a step of making a treatment decision based on the assessment. Additional embodiments of the present disclosure pertain to a computing device for assessing one or more mitochondrial or metabolic disorders in a subject in accordance with the methods of the present disclosure. |
| FILED | Monday, January 29, 2024 |
| APPL NO | 18/425248 |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/20 (20190201) G16B 25/10 (20190201) Original (OR) Class G16B 40/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257921 | Madrid et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter B. Madrid (San Jose, California); Nathan Collins (San Mateo, California); Mario Latendresse (Menlo Park, California); Jeremiah Malerich (San Jose, California); Markus Krummenacker (Hayward, California) |
| ABSTRACT | Retrosynthetic methods are described for determining one or more optimal synthetic routes to generate a target compound. |
| FILED | Monday, April 15, 2024 |
| APPL NO | 18/635717 |
| CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 10/00 (20190201) G16C 20/10 (20190201) G16C 20/70 (20190201) Original (OR) Class G16C 20/80 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257971 | Killgore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William Killgore (Tucson, Arizona); Janet Roveda (Tucson, Arizona); Jerzy Rozenblit (Tucson, Arizona); Ao Li (Tucson, Arizona); Huayu Li (Tucson, Arizona) |
| ABSTRACT | A virtual reality neuropsychological assessment (VRNA) system uses a deep learning network and a VR headset to administer multi-domain assessments of human cognitive performance. The deep learning network is trained to identify features in sensor data indicative of neuropsychological performance and classify users based on the features identified in the sensor data. The VR headset provides a user with a virtual simulation of an activity involving decision-making scenarios. During the virtual simulation, sensor data via a plurality of sensors of the VR headset is captured. The sensor data is applied to the deep learning network to identify features of the user and classify the user based on the features into a neuropsychological domains, such as attention, memory, processing speed, and executive function. Sensor data includes eye-tracking, hand-eye motor coordination, reaction time, working memory, learning and delayed memory, and inhibitory control. |
| FILED | Thursday, February 01, 2024 |
| APPL NO | 18/430445 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257976 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Edison T. Liu (Bar Harbor, Maine); Francesca Menghi (West Hartford, Connecticut) |
| ABSTRACT | Provided herein, in some embodiments, are methods for classifying the tandem duplicator phenotype of a tumor. |
| FILED | Tuesday, March 12, 2024 |
| APPL NO | 18/602428 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/15 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/10 (20190201) G16B 20/20 (20190201) G16B 40/10 (20190201) G16B 40/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/00 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258384 | Shinohara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Teledyne Scientific and Imaging, LLC (Thousand Oaks, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keisuke Shinohara (Thousand Oaks, California); Casey King (Newbury Park, California); Eric Regan (Moorpark, California); Miguel Urteaga (Moorpark, California) |
| ABSTRACT | Laterally-gated transistors and lateral Schottky diodes are disclosed. The FET includes a substrate, source and drain electrodes, channel, a gate electrode structure, and a dielectric layer. The gate electrode structure includes an electrode in contact with the channel and a lateral field plate adjacent to the electrode. The dielectric layer is disposed between the lateral field plate and the channel. The lateral field plate contacts the dielectric layer and to modulate an electric field proximal to the gate electrode proximal to the drain or source electrodes. Also disclosed is a gate electrode structure with lateral field plates symmetrically disposed relative to the gate electrode. Also disclosed in a substrate with dielectric structures buried in the substrate remote from the gate electrode structure. A lateral Schottky diode having an anode structure includes an anode (A), cathodes (C) and lateral field plates located between the anode and the cathodes. |
| FILED | Tuesday, March 19, 2024 |
| APPL NO | 18/609778 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/404 (20130101) Original (OR) Class H01L 29/778 (20130101) H01L 29/872 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258596 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yan Wang (Shrewsbury, Massachusetts); Zeyi Yao (Worcester, Massachusetts); Xiaotu MA (Worcester, Massachusetts) |
| ABSTRACT | A purification process for recycled graphite for use as anode material in Li-ion batteries includes a sequence of leaching and heat treatment followed by washing with deionized (DI) water and an acid wash. A graphite source results from a suitable process such as acid leaching of black mass from a battery recycling stream, where the leach removes a substantial portion of metal salts used for cathode materials. Impurities, most notably aluminum oxide and residual cathode materials, are often present in trace amounts in the graphite source. A sequence of heating (sintering) and pH adjusted washing further purifies the graphite into a modified, recycled graphite exceeding 99.5% purity for use in a recycled battery. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/427320 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/21 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2006/40 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 1/16 (20130101) C22B 7/007 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/583 (20130101) H01M 10/54 (20130101) Original (OR) Class H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258769 | Puckett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Matthew Wade Puckett (Phoenix, Arizona); Neal Eldrich Solmeyer (Edina, Minnesota); Karl D. Nelson (Plymouth, Minnesota); Jianfeng Wu (Tucson, Arizona); Mary Salit (Plymouth, Minnesota) |
| ABSTRACT | A laser device comprises a gain chip that emits light, and a photonics chip optically coupled to the gain chip. The photonics chip comprises a waveguide platform including an input waveguide optically coupled to the gain chip. The input waveguide optical communicates with a cascaded arrangement of waveguide grating structures on the waveguide platform. The grating structures comprise a first grating structure that produces a single resonance frequency within a stopband, and a second grating structure in optical communication with the first grating structure. The second grating structure diffracts a narrowband resonance, overlapping with the stopband of the first grating structure, back toward the gain chip, while passing any light outside of the stopband of the first grating structure out of the waveguide platform. The grating structures cooperate to yield a single resonance frequency that feeds back into the gain chip to produce a self-injection lock for the laser device. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/162517 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/10092 (20130101) H01S 5/12 (20130101) H01S 5/50 (20130101) H01S 5/141 (20130101) Original (OR) Class H01S 5/323 (20130101) H01S 5/1007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258771 | Chan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Philip Chan (Goleta, California); Steven P. DenBaars (Goleta, California); Shuji Nakamura (Santa Barbara, California) |
| ABSTRACT | A III-nitride based device is fabricated having an in-plane lattice constant or strain that is more than 30% biaxially relaxed, by creating a III-nitride based decomposition stop layer on or above a III-nitride based decomposition layer, wherein a temperature is increased to decompose the III-nitride based decomposition layer; and growing a III-nitride based device structure on or above the III-nitride based decomposition stop layer. The III-nitride based device structure includes at least one of an n-type layer, active layer, and p-type layer, and at least one of the n-type layer, active layer and p-type layer has an in-plane lattice constant or strain that is preferably more than 30% biaxially relaxed, more preferably 50% or more biaxially relaxed, and most preferably at least 70% biaxially relaxed. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 18/559654 |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/2068 (20130101) H01S 5/34333 (20130101) Original (OR) Class H01S 2301/173 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240259112 | ADIB et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Fadel ADIB (Cambridge, Massachusetts); Waleed AKBAR (Cambridge, Massachusetts); Aline EID (Ann Arbor, Michigan); John Clayton RADEMACHER, JR. (Somerville, Massachusetts); Purui WANG (Cambridge, Massachusetts) |
| ABSTRACT | Described herein is a retroreflective underwater backscatter node comprising a receiver that receives an incoming acoustic signal from a first direction; a reflector that reflects back an incoming acoustic signal in a second direction; and a modulator coupled to the reflector to modulate the reflected incoming acoustic signal as a back-scattered signal. In some embodiments, the first direction and second direction are substantially the same such that the retroreflective underwater backscatter node retro-directs an incoming acoustic signal as a back-scattered signal and incoming and back-scattered acoustic signals propagate in the same but substantially opposite directions. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424033 |
| CURRENT CPC | Transmission H04B 11/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240259313 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nytell Software LLC (Wilmington, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kirk Chang (Morganville, New Jersey); Gi Tae Kim (Morristown, New Jersey); John Unger (Bud Lake, New Jersey); John Sucec (Piscataway, New Jersey); Sunil Samtani (East Newark, New Jersey) |
| ABSTRACT | In a secure network where the network characteristics are not known, a call admission control algorithm and a preemption control algorithm based on a destination node informing the source node of the observed carried traffic are used to regulate the amount of traffic that needs to be preempted by the source. The amount of traffic that needs to be preempted is based on the carried traffic measured at the destination node. The traffic to be preempted is based on the priority of the traffic, where the lowest priority traffic is the first to be preempted until the amount of traffic preempted is sufficient to allow the remaining traffic to pass through the network without congestion. |
| FILED | Monday, October 23, 2023 |
| APPL NO | 18/382888 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/10 (20130101) Original (OR) Class H04L 47/11 (20130101) H04L 47/70 (20130101) H04L 47/245 (20130101) H04L 47/805 (20130101) H04L 47/822 (20130101) H04L 47/2408 (20130101) H04L 47/2433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20240252087 | Mendenhall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); UPMC (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); UPMC (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | George Stuart Mendenhall (Pittsburgh, Pennsylvania); Matthew Jones (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed are wearable bands, such as rings, for monitoring and diagnosing cardiovascular conditions of a wearer, along with related systems, algorithms, and methods. The disclosed wearable bands can continuously monitor the wearer's cardiovascular status by measuring heart rate and/or other physiological properties of the wearer. Disclosed wearable bands can further comprise at least two EKG electrodes, including a first electrode on the inner surface adapted to detect a signal from the finger and a second electrode on the outer surface adapted to detect a cardiovascular signal from another body part. The wearable bands can be linked wirelessly to a mobile device that the person can interact with. The mobile device can be linked to other distributed system components and healthcare providers, such as to send a message to a predetermined recipient based upon the physiological properties measured by the wearable band. |
| FILED | Friday, April 12, 2024 |
| APPL NO | 18/634133 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/11 (20130101) A61B 5/0022 (20130101) A61B 5/25 (20210101) Original (OR) Class A61B 5/0205 (20130101) A61B 5/349 (20210101) A61B 5/389 (20210101) A61B 5/683 (20130101) A61B 5/02438 (20130101) A61B 5/6826 (20130101) A61B 5/7275 (20130101) A61B 5/14552 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/048 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252096 | GROVER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | PULKIT GROVER (Pittsburgh, Pennsylvania); ALIREZA CHAMANZAR (Pittsburgh, Pennsylvania); MARLENE BEHRMANN COHEN (Pittsburgh, Pennsylvania) |
| ABSTRACT | A novel method for using the widely-used electroencephalography (EEG) systems to detect and localize silences in the brain is disclosed. The method detects the absence of electrophysiological signals, or neural silences, using noninvasive scalp electroencephalography (EEG) signals. This method can also be used for reduced activity localization, activity level mapping throughout the brain, as well as mapping activity levels in different frequency bands. By accounting for the contributions of different sources to the power of the recorded signals and using a hemispheric baseline approach and a convex spectral clustering framework, the method permits rapid detection and localization of regions of silence in the brain using a relatively small amount of EEG data. |
| FILED | Thursday, January 11, 2024 |
| APPL NO | 18/410446 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/372 (20210101) Original (OR) Class A61B 5/7264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252438 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Liangfang Zhang (San Diego, California); Che-Ming (Jack) Hu (San Diego, California); Ronnie Hongbo Fang (Irvine, California); Jonathan Copp (La Jolla, California) |
| ABSTRACT | Provided are nanoparticles and methods of using and making thereof. The inventive nanoparticle comprises a) an inner core comprising a non-cellular material; and b) an outer surface comprising a cellular membrane derived from a cell or a membrane derived from a virus. Medicament delivery systems or pharmaceutical compositions comprising the inventive nanoparticles are also provided. Further provided are immunogenic compositions comprising the inventive nanoparticles, and methods of using the inventive immunogenic compositions for eliciting an immune response, and for treating or preventing diseases or condition, such as neoplasm or cancer, or disease or conditions associated with cell membrane inserting toxin. Vaccines comprising the immunogenic composition comprising the nanoparticles are also provided. |
| FILED | Tuesday, February 20, 2024 |
| APPL NO | 18/582123 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/148 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 39/085 (20130101) A61K 39/001102 (20180801) A61K 45/06 (20130101) A61K 2039/80 (20180801) A61K 2039/55555 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252553 | BEHKAM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bahareh BEHKAM (Blacksburg, Virginia); Eric LEAMAN (Blacksburg, Virginia) |
| ABSTRACT | Cancer is a significant cause of mortality and morbidity worldwide. One of the principal impediments to the broad success of conventional chemotherapy is poor delivery to and transport within the tumor microenvironment (TME), caused by irregular and leaky vasculature, the lack of functional lymphatics, and underscored by the overproduction of extracellular matrix (ECM) proteins such as collagen. Described herein are engineered Salmonella Typhimurium (S. Typhimurium) bacteria and uses thereof. In some embodiments, the engineered S. Typhimurium bacteria comprises an exogenous collagenase. Also described in exemplary embodiments herein methods of using the engineered S. Typhimurium bacteria, such as part of a,cancer therapy. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 18/578856 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) C12N 15/74 (20130101) Enzymes C12Y 304/24003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252677 | Percec et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Virgil Percec (Philadelphia, Pennsylvania); Drew Weissman (Philadelphia, Pennsylvania); Dapeng Zhang (Philadelphia, Pennsylvania); Elena Atochina-Vasserman (Huntingdon Valley, Pennsylvania); Devendra Maurya (Philadelphia, Pennsylvania); Qi Xiao (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention relates to amphiphilic Janus dendrimers which may form nanoparticles. The invention also relates to methods of inducing an adaptive immune response in a subject comprising administering to the subject an effective amount of a composition comprising at least one nucleoside-modified RNA encoding at least one antigen and at least one amphiphilic Janus dendrimer and to methods of delivering an agent to a subject in need thereof, said method comprising the step of delivering to the subject a composition comprising an agent encapsulated by a nanoparticle. |
| FILED | Tuesday, May 24, 2022 |
| APPL NO | 18/563503 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 39/385 (20130101) A61K 47/542 (20170801) A61K 47/545 (20170801) A61K 48/0033 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240252726 | Cullen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); Wisberty J. Gordian-Velez (Philadelphia, Pennsylvania); H. Isaac Chen (Penn Valley, Pennsylvania); Jason A. Burdick (Philadelphia, Pennsylvania) |
| ABSTRACT | In various aspects and embodiments the present disclosure provides a construct comprising a pre-formed neural network, the construct comprising a micro-column comprising an outer sheath comprising a hyaluronic acid (HA) hydrogel, and a core comprising an extracellular matrix (ECM); a plurality of neurons within the micro-column. The present disclosure further provides methods of making and using the same. |
| FILED | Wednesday, May 18, 2022 |
| APPL NO | 18/561507 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/58 (20130101) A61L 27/383 (20130101) A61L 27/3633 (20130101) A61L 27/3675 (20130101) A61L 27/3878 (20130101) Computer Systems Based on Specific Computational Models G06N 3/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253108 | Sundaram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Subramanian Sundaram (Allston, Massachusetts); Christopher S. Chen (Newton, Massachusetts) |
| ABSTRACT | Methods and materials for forming a three-dimensional (3D) structure in a material are described. An example method includes directing a liquid casting material into a mold cavity of a mold structure, where the mold cavity corresponds to a three-dimensional (3D) structure. The method further includes causing the liquid casting material to solidify within the mold cavity to form a solid structure of the casting material, removing at least a portion of the mold structure from the solid structure of the casting material, and forming a structural material around the solid structure of the casting material. The solid casting material is liquified within the structural material. The liquified casting material is evacuated from the structural material to form the 3D structure in the structural material. |
| FILED | Thursday, January 25, 2024 |
| APPL NO | 18/422963 |
| CURRENT CPC | Foundry Moulding B22C 7/02 (20130101) B22C 9/043 (20130101) Original (OR) Class Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/405 (20130101) B29C 33/3842 (20130101) B29C 39/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240253661 | ROY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Debashri ROY (Arlington, Massachusetts); Kaushik CHOWDHURY (Needham, Massachusetts) |
| ABSTRACT | Systems and methods are provided for selecting a beam direction of mm wave transmission for use by a vehicle operating within a network environment. The systems and methods include collecting data from a plurality of sensors on the vehicle to detect obstructions and other changes to an environment of the vehicle and of a base station that communicates with the vehicle. The systems and methods further include a library of digital twins, which are a virtual representation of the real-world environment, to identify beam directions of varying signal-to-noise ratios. The systems and methods further include determining from the data collected from the plurality of sensors a preferred digital twin and using the beam direction data corresponding to the digital twin to determine a beam direction for a transmitter of the vehicle to communicate with a receiver of the base station. |
| FILED | Thursday, January 25, 2024 |
| APPL NO | 18/423247 |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 60/001 (20200201) Original (OR) Class B60W 2420/403 (20130101) Wireless Communication Networks H04W 4/44 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254062 | Noe-Hays et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Abraham Noe-Hays (Ann Arbor, Michigan); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abraham Noe-Hays (Putney, Vermont); Nancy G. Love (Ann Arbor, Michigan) |
| ABSTRACT | A system for generating a concentrated product from a feedstock includes a reciprocating concentration system that includes first and second chambers to which the feedstock is alternately provided and from which the concentrated product is alternately removed, and a heat transfer system in thermal communication with the first and second chambers, the heat transfer system being configured to reversibly transfer heat between the first and second chambers such that the first chamber alternates between melting a frozen portion of the feedstock in the second chamber and having a frozen portion of the feedstock in the first chamber melted by the feedstock in the second chamber. The system further includes a heat dump system in thermal communication with the reciprocating concentration system, the heat dump system being configured to remove heat from the reciprocating concentration system. |
| FILED | Tuesday, January 09, 2024 |
| APPL NO | 18/408482 |
| CURRENT CPC | Separation B01D 9/0013 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/10 (20130101) Nitrogenous Fertilisers C05C 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254127 | Emrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (BOSTON, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Todd Emrick (South Deerfield, Massachusetts); Matthew Skinner (Amherst, Massachusetts); Sarah M. Ward (Amherst, Massachusetts); Banishree Saha (Greenfield, Massachusetts) |
| ABSTRACT | A temozolomide compound according to formula (I) is described, wherein R1, L1, and X are defined herein. The temozolomide compound can be used to prepare polymers comprising temozolomide. Additionally, the polymers comprising temozolomide can be particularly useful in the treatment of certain diseases. |
| FILED | Wednesday, January 10, 2024 |
| APPL NO | 18/408929 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/787 (20130101) A61K 47/58 (20170801) A61K 47/60 (20170801) A61K 47/545 (20170801) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 22/10 (20130101) C08F 220/365 (20200201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254146 | Dias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rasika Dias (Arlington, Texas); Mukundam Vanga (Arlington, Texas) |
| ABSTRACT | Disclosed herein are poly(pyridyl)borate ligands and metal complexes comprising the poly(pyridyl)borate ligands. Also disclosed herein are methods of making and methods of using said poly(pyridyl)borate ligands and metal complexes comprising the poly(pyridyl)borate ligands. Also disclosed herein are methods of preparing a poly(pyridyl)borate ligand comprising reacting a boron precursor comprising a trifluoroborate to form the poly(pyridyl)borate ligand. |
| FILED | Friday, December 22, 2023 |
| APPL NO | 18/394113 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/00 (20130101) C07F 1/08 (20130101) C07F 5/027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254283 | TESSONNIER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jean-Philippe TESSONNIER (Ames, Iowa); Brent Howard SHANKS (Ames, Iowa); Eric William COCHRAN (Ames, Iowa); Joseph Eugene HADEL (Ames, Iowa); Marco Nazareno DELL'ANNA (Ames, Iowa); Prerana CARTER (Ames, Iowa); Dustin GANSEBOM (Ames, Iowa) |
| ABSTRACT | The present application is directed to processes for the preparation of compounds of Formulae (I), (IV), and (IVb) as described herein. The application further relates to compounds of Formula (IVb) as described herein. Additional embodiments are directed to a processes for the preparation of polymers of Formulae (X), (XVIII), (XIII), and (XIV) as well as to polymers of Formula (XIII) also described herein. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 18/027480 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/353 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254321 | Calabrese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Michelle Anna Calabrese (Minneapolis, Minnesota); Benjamin Per Robertson (Minneapolis, Minnesota); Gerald Edmund Rott (Minneapolis, Minnesota) |
| ABSTRACT | Microbeads including about 50 wt % to about 99 wt % cellulose and about 1 wt % to about 50 wt % lignin. An average diameter of the microbeads is in a range of about 25 microns to about 1500 microns. Producing the microbeads includes dissolving cellulose and lignin in a solvent to yield a biomass solution, introducing the biomass solution into oil to yield a first mixture, adding an anti-solvent to the first mixture to yield a second mixture, and precipitating the microbeads from the second mixture. |
| FILED | Thursday, February 01, 2024 |
| APPL NO | 18/430203 |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/14 (20130101) C08J 2301/02 (20130101) C08J 2397/00 (20130101) Compositions of Macromolecular Compounds C08L 1/02 (20130101) Original (OR) Class C08L 97/005 (20130101) C08L 2201/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254431 | Tsioris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ONECYTE BIOTECHNOLOGIES, INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | ONECYTE BIOTECHNOLOGIES, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Konstantinos Tsioris (Swampscott, Massachusetts); Ayca Yalcin Ozkumur (Newton Highlands, Massachusetts) |
| ABSTRACT | Provided herein are methods and systems for high-throughput cell line development. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 18/034488 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/16 (20130101) C12M 41/48 (20130101) C12M 47/04 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10056 (20130101) G06T 2207/20081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254637 | JIAO et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Delaware (Newark, Delaware) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Feng JIAO (Newark, New Jersey); Matthew JOUNY (Easton, Pennsylvania); Jing-Jing LV (Nanjing, China PRC) |
| ABSTRACT | Disclosed herein is a method of electroreduction with a working electrode and counter electrode. The method includes a step of electrocatalyzing carbon monoxide and/or carbon dioxide in the presence of one or more nucleophilic co-reactants in contact with a catalytically active material present on the working electrode, thereby forming one or more carbon-containing products electrocatalytically. |
| FILED | Monday, March 04, 2024 |
| APPL NO | 18/594354 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/23 (20210101) C25B 3/26 (20210101) Original (OR) Class C25B 9/19 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254839 | Tao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Junliang Tao (Chandler, Arizona); Sichuan Huang (Tempe, Arizona); Yong Tang (Tempe, Arizona); Yi Zhong (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Junliang Tao (Chandler, Arizona); Sichuan Huang (Tempe, Arizona); Yong Tang (Tempe, Arizona); Yi Zhong (Tempe, Arizona) |
| ABSTRACT | A burrowing apparatus may comprise an anterior segment and a posterior segment coupled by a linear actuator that is configured to extend and contract the distance between the anterior segment and the posterior segment to effectuate horizontal translation of the burrowing apparatus in a granular medium. The anterior segment may further comprise a conical tip. The conical tip may be configured to rotate relative to the anterior segment, and the conical tip may be an auger. The rotation of the conical tip while the linear actuator extends and contracts may create kinetic asymmetry that may be beneficial to the net horizontal translation in the granular medium. The burrowing apparatus may be advantageously used in applications, for example, in geotechnical subsurface investigation, extraterrestrial exploration, underground contamination detection, and precision agriculture. |
| FILED | Wednesday, January 10, 2024 |
| APPL NO | 18/409006 |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 7/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240254958 | Orona et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ocean Motion Technologies, Inc. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander J. Orona (San Diego, California); Boyang Pan (San Diego, California); Leverett Bezanson (Alpine, California); Paul Glick (Santa Cruz, California); Justin Walraven (San Diego, California); Mark Huang (Spring Valley, California); Nathaniel Bell (Tacoma, Washington) |
| ABSTRACT | A wave energy capture system deployed in water converts mechanical motion induced by waves in the water to electrical energy. A controller of the wave energy capture system receives input regarding real-time wave conditions in a vicinity of the wave energy capture system. The controller applies a control model to the received input to select a value of a control parameter for the wave energy capture system, where the control model includes a model that has been trained using machine learning to take wave condition data as input and to output control parameter values selected based on the wave condition data in order to increase an amount of energy captured by the wave energy capture system. The controller implements the selected value of the control parameter on the wave energy capture system. |
| FILED | Wednesday, March 20, 2024 |
| APPL NO | 18/611443 |
| CURRENT CPC | Machines or Engines for Liquids F03B 13/20 (20130101) F03B 15/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255284 | Jacobs et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); Albert-Ludwigs-Universität Freiburg Freiburg (DE) (Freiburg, Germany) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tevis Jacobs (Pittsburgh, Pennsylvania); Lars Pastewka (Freiburg, Germany); Paul Strauch (Eschborn, Germany); Antoine Sanner (Zürich, Switzerland); Michael Röttger (Freiburg, Germany) |
| ABSTRACT | A method of characterizing a surface topography includes determining scale-dependent parameters. Each of the scale-dependent parameters represents a statistical characterization of a distribution of at least one of a first-order or higher-order derivative of surface height or h determined from one or more measurements of the surface at each of multiple distance scales. For at least one of the one or more measurements, the first-order or higher-order derivative of surface height is determined at the multiple distance scales in real space defined via a scaling factor η which is greater than or equal to 1 and which is multiplied by the smallest possible distance scale or resolution provided by the at least one of the one or more measurements. |
| FILED | Saturday, June 24, 2023 |
| APPL NO | 18/340845 |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255362 | WANG et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sihong WANG (Chicago, Illinois); Qi SU (Chicago, Illinois); Yang LI (Chicago, Illinois) |
| ABSTRACT | A soft pressure sensor comprises a stretchable top electrode, a stretchable bottom electrode, and an array of peaked structures between the stretchable top and bottom electrodes. The peaked structures comprise protruding regions of a continuous film conformally overlying an array of stiffening electrodes on the stretchable bottom electrode, where a tip of each protruding region is in contact with the stretchable top electrode and a base of each stiffening electrode is in contact with the stretchable bottom electrode. The soft pressure sensor includes one or more spacers extending between and bonded to the stretchable top electrode and the continuous film on the stretchable bottom electrode, where each of the one or more spacers is positioned outside the array of peaked structures. A capacitance measured by the soft pressure sensor is substantially invariant under in-plane stretching and/or bending. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 18/290499 |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/142 (20130101) Original (OR) Class G01L 5/0061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255395 | Abbas et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abdennour Abbas (Lauderdale, Minnesota); Akli Zarouri (St. Paul, Minnesota) |
| ABSTRACT | A device for separating biological entities from a fluid sample, the device comprising: porous material comprising bound material, wherein the bound material functions to separate the biological entity from the fluid matrix. Devices including such porous media, methods of using such porous media and methods of making such porous media are also included herein. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 18/565948 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1017 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255517 | Carter et al. |
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| FUNDED BY |
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| APPLICANT(S) | Elektrofi, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tyler L. Carter (Newburyport, Massachusetts); Lyndon Fitzgerald Charles, Jr. (Medford, Massachusetts); Chase Spenser Coffman (Newton, Massachusetts); Daniel Benjamin Dadon (East Boston, Massachusetts); Zishu Gui (Boston, Massachusetts); Sadiqua Shadbar (Allston, Massachusetts); Chaitanya Sudrik (Stoneham, Massachusetts); Yi Tang (Medford, Massachusetts) |
| ABSTRACT | The present disclosure provides screening methods to predict stability of proteins in particle formulations during early stage drug development. In particular, the screening methods disclosed herein uses high throughput protocols that allow rapid identification of stable proteins in the particle formulations in a cost effective manner. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 18/565193 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6803 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255527 | Ozcan et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Aydogan Ozcan (Los Angeles, California); Hyou-Arm Joung (Los Angeles, California); Yi Luo (Los Angeles, California) |
| ABSTRACT | A quantitative particle agglutination assay device is disclosed that combines portable lens-free microscopy and deep learning for rapidly measuring the concentration of a target analyte. As one example of a target analyte, the assay device was used to test for high-sensitivity C-reactive protein (hs-CRP) using human serum samples. A dual-channel capillary lateral flow device is designed to host the agglutination reaction using a small volume of serum. A portable lens-free microscope records time-lapsed inline holograms of the lateral flow device, monitoring the agglutination process over several minutes. These captured holograms are processed, and at each frame the number and area of the particle clusters are automatically extracted and fed into shallow neural networks to predict the CRP concentration. The system can be used to successfully differentiate very high CRP concentrations (e.g., >10-500 μg/mL) from the hs-CRP range. |
| FILED | Tuesday, May 24, 2022 |
| APPL NO | 18/563745 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/075 (20240101) G01N 33/6893 (20130101) Original (OR) Class G01N 33/54388 (20210801) G01N 2333/4737 (20130101) G01N 2800/7095 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10056 (20130101) G06T 2207/20084 (20130101) G06T 2207/30004 (20130101) G06T 2207/30204 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/762 (20220101) G06V 20/698 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255597 | Theis et al. |
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| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina); Wayne State University (Detroit, Michigan); Board of Trustees of Southern Illinois University (Carbondale, Illinois); NATIONAL INSTITUTES OF HEALTH, NHLBI (Rockville, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas Theis (Raleigh, North Carolina); Mustapha Abdulmojeed (Raleigh, North Carolina); Sören Lehmkuhl (Raleigh, North Carolina); Patrick TomHon (Raleigh, North Carolina); Iuliia Mandzhieva (Raleigh, North Carolina); Eduard Y. Chekmenev (Detroit, Michigan); Isaiah Adelabu (Detroit, Michigan); Mohammad Kabir (Detroit, Michigan); Shiraz Nantogma (Detroit, Michigan); Jessica Ettedgui (Rockville, Maryland); Rolf Eric Swenson (Rockville, Maryland); Boyd Goodson (Carbondale, Illinois) |
| ABSTRACT | In one aspect, the disclosure relates to hyperpolarized target molecules and contrast agents comprising the same, methods of making the same, and methods of imaging using same. In a further aspect, imaging performed using the hyperpolarized target molecules and contrast agent can enable real time monitoring and diagnosis of diseases including various cancers and metabolic disorders. The methods are cryogen-free and inexpensive and can be performed in a short time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Tuesday, July 26, 2022 |
| APPL NO | 18/291681 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4608 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255751 | Blumenthal et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); United States Army (Adelphi, Maryland) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); United States Army (Adelphi, Maryland) |
| INVENTOR(S) | Daniel J. Blumenthal (Santa Barbara, California); Jiawei Wang (Goleta, California); Kaikai Liu (Santa Barbara, California); Ryan Q. Rudy (Adelphi, Maryland) |
| ABSTRACT | Disclosed herein is a stress optical modulator. The modulator include a circular piezo-electric actuator; and a ring waveguide separated from the circular piezo-electric actuator by a top cladding layer. The circular piezo-electric actuator may be offset from the ring waveguide such that a first circular portion of the circular piezo-electric actuator is located on the outside of the ring waveguide and a second circular portion of the circular piezo-electric actuator is located on the inside of the ring waveguide. The circular piezo-electric actuator may be configured to change the guiding properties of the ring waveguide based on the voltage applied to the circular piezo-electric actuator by inducing strain through the top cladding layer to change the optical properties of the ring waveguide. |
| FILED | Wednesday, October 11, 2023 |
| APPL NO | 18/485173 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4204 (20130101) G02B 26/0875 (20130101) Original (OR) Class Electric solid-state devices not otherwise provided for H10N 30/206 (20230201) H10N 30/877 (20230201) H10N 30/8554 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255829 | Moses et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey A. Moses (Ithaca, New York); Noah Flemens (Ithaca, New York); Nuno Vinicius (Richardson, Texas) |
| ABSTRACT | A third-harmonic generation method includes frequency-quadrupling a fundamental optical beam via cascaded second-harmonic generation to yield a fourth-harmonic optical beam. The method also includes down-converting the fourth-harmonic optical beam to yield a third-harmonic optical beam. A third harmonic generator includes a monolithic optical element having nonzero quadratic electric susceptibility to (i) frequency-quadruple a fundamental optical beam via cascaded second-harmonic generation, and (ii) down-convert a fourth-harmonic optical beam to yield a third-harmonic optical beam. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/427721 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/37 (20130101) G02F 1/354 (20210101) Original (OR) Class G02F 1/3548 (20210101) G02F 1/3553 (20130101) G02F 1/3558 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240256770 | Gurupur et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Varadraj Gurupur (Oviedo, Florida); Muhammed Shelleh (Orlando, Florida); Roger Azevedo (Oviedo, Florida) |
| ABSTRACT | A prediction system may train a neural network model to analyze data to predict sentiments associated with the data and a measure of incompleteness of the data. The prediction system may obtain communication data regarding a communication session between a first device and a second device. The communication data is obtained via a network. The prediction system may provide the communication data as an input to the trained neural network model. The prediction system may determine, using the trained neural network model, a first set of sentiments associated with the first device and a second set of sentiments associated with the second device. The prediction system may determine, using the trained neural network model, a measure of incompleteness of the communication data based on the first set of sentiments and the second set of sentiments. The prediction system may perform an action based on the measure of incompleteness. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424712 |
| CURRENT CPC | Electric Digital Data Processing G06F 40/205 (20200101) G06F 40/242 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257415 | MENTIS et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland); SORBONNE UNIVERSITE (Paris, France); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France); INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (Paris, France) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Helena MENTIS (Baltimore, Maryland); Jwawon Seo (Catonsville, Maryland); Ignacio Avellino (Paris, France) |
| ABSTRACT | The present disclosure provides an augmented reality, head mounted display, based collaborative system designed for remote instruction over live mobile views during physical tasks. The collaborative system includes a world-stabilized area where remote helpers can dynamically place a pointer and annotations on the physical environment, and an indirect input mechanism with an absolute position to the world-stabilized area. Examples provided within show how the described system worked for participants engaged in a remote instructional task and how they supported effective and efficient communication. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/427265 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/1454 (20130101) G06F 3/03547 (20130101) Image Data Processing or Generation, in General G06T 11/203 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257500 | Frank et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lawrence R. Frank (San Diego, California); Vitaly L. Galinsky (San Diego, California) |
| ABSTRACT | Analysis of complex spatio-temporal data within a dynamic system that includes spatial positions and fields, at least a portion of which are interacting, includes determining values of mean field at every spatial position, determining spatio-temporal eigenmodes in spatial-frequency space assuming interacting fields, and determining spatial and temporal interactions between the eigenmodes. The resulting display indicates space/time localization patterns that are indicative of connectivity within the dynamic system. |
| FILED | Thursday, March 14, 2024 |
| APPL NO | 18/605307 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/5608 (20130101) G01R 33/56341 (20130101) Electric Digital Data Processing G06F 18/2135 (20230101) G06F 18/24133 (20230101) G06F 2218/12 (20230101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/0016 (20130101) G06T 2207/10044 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20048 (20130101) G06T 2207/30016 (20130101) Image or Video Recognition or Understanding G06V 10/7715 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240257656 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kwangtaek Kim (Aurora, Ohio); Robert John Clements (Stow, Ohio); Jeremy Michael Jarzembak (Chagrin Falls, Ohio); John Timothy Dunlosky (Streetsboro, Ohio); Jennifer Rose Biggs (Aurora, Ohio); Ann James (Hartville, Ohio); Jin Woo Kim (Kent, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kwangtaek Kim (Aurora, Ohio); Robert John Clements (Stow, Ohio); Jeremy Michael Jarzembak (Chagrin Falls, Ohio); John Timothy Dunlosky (Streetsboro, Ohio); Jennifer Rose Biggs (Aurora, Ohio); Ann James (Hartville, Ohio); Jin Woo Kim (Kent, Ohio) |
| ABSTRACT | An assembly for training a user for intravenous (IV) catheter insertion includes a mixed reality display adapted to display a virtual patient and a virtual needle, the mixed reality display including a hand tracking module; a first haptic device including a stylus assembly with a needle assembly; a second haptic device adapted to allow the user to stabilize a hand; and a hand motion controller adapted to track the second haptic device in conjunction with the hand tracking module of the mixed reality display. A method includes utilizing a system to simulate inserting the virtual needle into an arm of the virtual patient with a first set of insertion conditions; adjusting the system to a second set of insertion conditions; and utilizing the system to simulate inserting the virtual needle into the arm of the virtual patient with the second set of insertion conditions. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/427112 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/014 (20130101) G06F 3/016 (20130101) G06F 3/03545 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) G06T 2210/41 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/02 (20130101) Original (OR) Class G09B 23/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258006 | Xiao et al. |
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| FUNDED BY |
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| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gang Xiao (Barrington, Rhode Island); Kang Wang (Providence, Rhode Island) |
| ABSTRACT | Systems and methods are provided that exploit local dynamics of a skyrmion to perform a computing function. A magnetic system hosts a skyrmion that transitions among a plurality of states, with each of the plurality of states having an associated switching probability. A bias source provides energy to the magnetic system as to adjust a switching probability associated with one of the plurality of states. A readout component measures a state of the skyrmion. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/102887 |
| CURRENT CPC | Static Stores G11C 11/18 (20130101) G11C 11/1673 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/3254 (20130101) Original (OR) Class Pulse Technique H03K 19/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258403 | Ahmad et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Iftikhar Ahmad (Irmo, South Carolina); Samiul Hasan (Columbia, South Carolina); Mohi Uddin Jewel (Columbia, South Carolina) |
| ABSTRACT | Described herein are methods, systems, and processes for in-situ oxide dielectric deposition in the same reactor, integrating III-Nitride and III-Oxide technology using N2 as carrier gas that results in a lower density of interface traps (charges). |
| FILED | Tuesday, November 28, 2023 |
| APPL NO | 18/520979 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/408 (20130101) H01L 29/517 (20130101) H01L 29/7786 (20130101) H01L 29/66462 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258564 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Seamus D. Jones (Goleta, California); Yanqiao Chen (Goleta, California); Peter Richardson (Santa Barbara, California); Raphaele Clement (Santa Barbara, California); Craig J. Hawker (Santa Barbara, California); Glenn H. Fredrickson (Santa Barbara, California); Rachel A. Segalman (Santa Barbara, California) |
| ABSTRACT | A solid electrolyte including zwitterionic compounds comprising zwitterionic molecules and/or charge neutral polymers with zwitterion pendants. A salt is distributed through the solid such that the solid conducts alkali metal ions obtained from the salt and the zwitterionic compounds each include zero or more amorphous regions and one or more crystalline regions characterized by (1) a presence of Bragg diffraction peaks in an X-ray diffraction measurement of the solid; and (2) the solid having an ion conductivity of at least 10−4 S/cm at a temperature of 50 degrees Celsius when a transport number for the alkali metal ions is at least 0.5 and a molar ratio of the salt to the zwitterionic units is 0.9. The electrolyte exhibits surprisingly high alkali metal ion conductivity and linear elastic modulus over a wide range of practically useful temperatures. |
| FILED | Tuesday, April 12, 2022 |
| APPL NO | 18/555081 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240259112 | ADIB et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Fadel ADIB (Cambridge, Massachusetts); Waleed AKBAR (Cambridge, Massachusetts); Aline EID (Ann Arbor, Michigan); John Clayton RADEMACHER, JR. (Somerville, Massachusetts); Purui WANG (Cambridge, Massachusetts) |
| ABSTRACT | Described herein is a retroreflective underwater backscatter node comprising a receiver that receives an incoming acoustic signal from a first direction; a reflector that reflects back an incoming acoustic signal in a second direction; and a modulator coupled to the reflector to modulate the reflected incoming acoustic signal as a back-scattered signal. In some embodiments, the first direction and second direction are substantially the same such that the retroreflective underwater backscatter node retro-directs an incoming acoustic signal as a back-scattered signal and incoming and back-scattered acoustic signals propagate in the same but substantially opposite directions. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424033 |
| CURRENT CPC | Transmission H04B 11/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240259706 | Gutierrez Barragan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Felipe Gutierrez Barragan (Alameda, California); Yuhao Liu (Madison, Wisconsin); Atul Ingle (Madison, Wisconsin); Mohit Gupta (Madison, Wisconsin); Andreas Velten (Madison, Wisconsin) |
| ABSTRACT | In accordance with some embodiments, systems, methods, and media for high dynamic range imaging using single-photon and conventional image sensor data are provided. In some embodiments, the system comprises: first detectors configured to detect a level of photons proportional to incident photon flux; second detectors configured to detect arrival of individual photons; a processor programmed to: receive, from the first detectors, first values indicative of photon flux from a scene with a first resolution; receive, from the second detectors, second values indicative of photon flux from the scene with a lower resolution; provide a first encoder of a trained machine learning model first flux values based on the first values, provide the second encoder of the model second flux values; receive, as output, values indicative of photon flux from the scene; and generate a high dynamic range image based on the third plurality of values. |
| FILED | Monday, September 11, 2023 |
| APPL NO | 18/464987 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14634 (20130101) H01L 27/14645 (20130101) Pictorial Communication, e.g Television H04N 25/585 (20230101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20240251785 | Pietrantonio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patricia V. Pietrantonio (College Station, Texas); Caixing Xiong (College Station, Texas); Dwight D. Baker (College Station, Texas) |
| ABSTRACT | Applicants have developed novel methods and compositions for controlling, treating, preventing, or ameliorating arthropod infection and identifying kinin receptor agonists and antagonists. Novel compositions include one or more active agents of small molecules antagonists or agonists of arthropod kinin receptor. Methods of preventing disease development and infestation by arthropods are disclosed as well as methods of making, using, and producing such compositions. |
| FILED | Wednesday, May 05, 2021 |
| APPL NO | 18/558995 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/006 (20130101) Original (OR) Class A01N 35/10 (20130101) A01N 37/22 (20130101) A01N 43/42 (20130101) A01N 43/52 (20130101) A01N 43/54 (20130101) A01N 43/56 (20130101) A01N 43/60 (20130101) A01N 43/78 (20130101) A01N 43/82 (20130101) A01N 43/84 (20130101) A01N 43/90 (20130101) A01N 43/707 (20130101) A01N 43/713 (20130101) A01N 47/44 (20130101) A01N 47/48 (20130101) A01N 51/00 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 7/02 (20210801) A01P 7/04 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240255395 | Abbas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abdennour Abbas (Lauderdale, Minnesota); Akli Zarouri (St. Paul, Minnesota) |
| ABSTRACT | A device for separating biological entities from a fluid sample, the device comprising: porous material comprising bound material, wherein the bound material functions to separate the biological entity from the fluid matrix. Devices including such porous media, methods of using such porous media and methods of making such porous media are also included herein. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 18/565948 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1017 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20240255541 | Barry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dwight David Atherly Barry (Jefferson, Maryland); Nicholas George Paulter, Jr. (Silver Spring, Maryland) |
| ABSTRACT | A chronograph system has with a set of co-located start planes and a set of co-located stop planes spaced from the start planes, thereby minimizing measurement differences. |
| FILED | Monday, January 29, 2024 |
| APPL NO | 18/426179 |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/685 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240260484 | Najafi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PsiQuantum Corp. (Palo Alto, California); Government of the United States of America, as Represented by the Secretary of Commerce (, None) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Faraz Najafi (Palo Alto, California); Qiaodan Jin Stone (Sunnyvale, California); Adam Nykoruk McDaughan (Denver, Colorado) |
| ABSTRACT | An example electric circuit includes a superconductor component having a first terminal at a first end and a second terminal at a second end. The superconductor component includes a first portion coupled to the first terminal, a second portion coupled to the second terminal, and a third portion coupling the first portion and the second portion. The third portion has a curved shape such that the first portion of the superconductor component is proximate to, and thermally coupled to, the second portion of the superconductor component. The example electric circuit further includes a coupling component coupled to the third portion of the superconductor component, and a gate component configured to generate a resistive heat that exceeds a superconducting threshold temperature of the superconductor component, where the gate component is separated from the superconductor component by the coupling component. |
| FILED | Wednesday, April 10, 2024 |
| APPL NO | 18/632077 |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/04 (20130101) Electric solid-state devices not otherwise provided for H10N 60/30 (20230201) Original (OR) Class H10N 60/84 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20240252726 | Cullen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); Wisberty J. Gordian-Velez (Philadelphia, Pennsylvania); H. Isaac Chen (Penn Valley, Pennsylvania); Jason A. Burdick (Philadelphia, Pennsylvania) |
| ABSTRACT | In various aspects and embodiments the present disclosure provides a construct comprising a pre-formed neural network, the construct comprising a micro-column comprising an outer sheath comprising a hyaluronic acid (HA) hydrogel, and a core comprising an extracellular matrix (ECM); a plurality of neurons within the micro-column. The present disclosure further provides methods of making and using the same. |
| FILED | Wednesday, May 18, 2022 |
| APPL NO | 18/561507 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/58 (20130101) A61L 27/383 (20130101) A61L 27/3633 (20130101) A61L 27/3675 (20130101) A61L 27/3878 (20130101) Computer Systems Based on Specific Computational Models G06N 3/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240256043 | Hochberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leigh Hochberg (Brookline, Massachusetts); John D. Simeral (Providence, Rhode Island); Tyler Singer-Clark (Falmouth, Massachusetts); Ronnie Gross (Portsmouth, Rhode Island); Thomas Hosman (Providence, Rhode Island); Anastasia Kapitonava (Boston, Massachusetts); Rekha Crawford (Providence, Rhode Island) |
| ABSTRACT | Instances of a single brain computer interface (BCI) system can be implemented on multiple devices. An active instance can control the associated device. The instances can each communicate with a neural decoding system that can receive neural signals from a user, process the neural signals, and output a command based on the processed neural signals. A device running the active instance of can be in communication with the neural decoding system to receive a command. The device can include a display, a non-transitory memory storing instructions, and a processor to execute the instructions to: run an instance of a control program; and execute the task based on the command. |
| FILED | Wednesday, March 20, 2024 |
| APPL NO | 18/610476 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/015 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 20240259301 | Bataineh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abdulla M. Bataineh (Vista, California); Thomas L. Court (Three Lakes, Wisconsin); Edwin L. Froese (Burnaby, Canada) |
| ABSTRACT | Systems and methods are provided for efficiently routing data through a network having a plurality of switches configured in a fat-tree topology, including: receiving a data transmission comprising a plurality of packets at an edge port of the network, and routing the data transmission through the network with routing decisions based upon a routing table, wherein the routing table includes entries to effect routing decisions based upon a destination based hash function. |
| FILED | Tuesday, April 09, 2024 |
| APPL NO | 18/630121 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/28 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/02 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240259302 | Froese |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edwin L. Froese (Burnaby, Canada) |
| ABSTRACT | Systems and methods are provided for managing a data communication within a multi-level network having a plurality of switches organized as groups, with each group coupled to all other groups via global links, including: at each switch within the network, maintaining a global fault table identifying the links which lead only to faulty global paths, and when the data communication is received at a port of a switch, determine a destination for the data communication and, route the communication across the network using the global fault table to avoid selecting a port within the switch that would result in the communication arriving at a point in the network where its only path forward is across a global link that is faulty; wherein the global fault table is used for both a global minimal routing methodology and a global non-minimal routing methodology. |
| FILED | Wednesday, April 10, 2024 |
| APPL NO | 18/631217 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/28 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/02 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 20240254045 | Hojati et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Maryam Hojati (Albuquerque, New Mexico); Amir Bakhshi (Albuquerque, New Mexico); Muhammad Saeed Zafar (Albuquerque, New Mexico) |
| ABSTRACT | A 3D-printable, self-reinforced ultra-ductile cementitious material comprising; a mix of 50 percent cement and 50 percent mineral admixture. |
| FILED | Wednesday, January 31, 2024 |
| APPL NO | 18/429262 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/10 (20200101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 7/02 (20130101) C04B 14/106 (20130101) C04B 16/0625 (20130101) C04B 16/0641 (20130101) Original (OR) Class C04B 18/08 (20130101) C04B 18/067 (20130101) C04B 18/146 (20130101) C04B 2111/00181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240252437 | Castor |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aphios Corporation (Arlington, Massachusetts) |
| ASSIGNEE(S) | Aphios Corporation (Arlington, Massachusetts) |
| INVENTOR(S) | Trevor Percival Castor (Arlington, Massachusetts) |
| ABSTRACT | A method is disclosed for producing targeted nanoencapsulated therapeutics in a microgravity environment using supercritical, critical and near-critical fluids with and without polar cosolvents. Using the disclosed technology, nanosomes for delivering Bryostatin-1 and other Bryoids are produced in microgravity. The resulting nanosomes are smaller, more uniform, with a higher surface area to volume than those produced in gravity-based environments and have an average diameter between 0.001 to 20.000 nanometer. The resultant therapeutics may be used for treating chronic diseases such as cancer, HIV, and Alzheimer's disease. |
| FILED | Friday, April 12, 2024 |
| APPL NO | 18/634819 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1277 (20130101) Original (OR) Class A61K 31/35 (20130101) A61K 47/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 20240252617 | Saunders et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Saunders (Durham, North Carolina); Barton F. Haynes (Durham, North Carolina) |
| ABSTRACT | The invention is directed to coronavirus based immunogens, including immunogens comprising spike protein and or domains thereof, comprised in multimeric complexes. Provided are also methods of using these immunogens to induce immunogenic responses in a subject. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 18/276798 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/575 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) C07K 14/435 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/20022 (20130101) C12N 2770/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 20240255558 | Allwine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (FALLS CHURCH, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott F. Allwine (Leesburg, Virginia); Sunny Bagga (Corona, California); Brian J. Cadwell (Pasadena, Maryland); Shaun Mark Goodwin (East New Market, Maryland) |
| ABSTRACT | This disclosure relates to systems and methods for measuring impedance characteristics of a cryogenic device under test (DUT). A channel select circuit can be configured in a first state to electrically isolate a channel output circuit from the cryogenic DUT and in a second state to electrically couple the channel output circuit to the cryogenic DUT, and at least one resistor can be positioned along a transmission path that couples a pattern generator circuit to a channel output circuit that includes the channel select circuit. A controller can be configured to cause respective test current signals to be provided along the transmission path when the channel select circuit is in respective first and second states to establish respective first and second voltages across the at least one resistor, determine first and second impedance characteristics of the transmission path for determining an impedance of the cryogenic DUT. |
| FILED | Tuesday, April 09, 2024 |
| APPL NO | 18/630577 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 27/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240258685 | TAYLOR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EAGLE TECHNOLOGY, LLC (Melbourne, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert M. TAYLOR (Rockledge, Florida); Christopher L. ROSE (Palm Bay, Florida); John CARRO (Melbourne, Florida); Richard I. HARLESS (Melbourne, Florida); Miguel ORTEGA-MORALES (Vero Beach, Florida); Timothy L. FETTERMAN (Palm Bay, Florida); David LOPEZ (Malabar, Florida) |
| ABSTRACT | A space antenna may include an extendible boom movable between stored and deployed positions. An extendible hoop may surround the extendible boom and is movable between the stored and deployed positions. A front cord arrangement may be coupled to the extendible hoop and defines a curved shape in the deployed position, and a reflective layer may be carried thereby. A rear cord arrangement may be behind the front cord arrangement and coupled between the extendible hoop and the extendible boom. The rear cord arrangement may include a rear plurality of interconnected cords defining rear polygons. Tie cords may extend between the front cord arrangement and the rear cord arrangement. A top cord arrangement may be above the reflective layer and coupled between the hoop and the extendible boom. |
| FILED | Wednesday, January 18, 2023 |
| APPL NO | 18/155797 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/288 (20130101) Original (OR) Class H01Q 1/1228 (20130101) H01Q 15/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, August 01, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240801.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page