FedInvent™ Patent Applications
Application Details for Thursday, August 15, 2024
This page was updated on Saturday, August 17, 2024 at 08:41 PM GMT
Department of Health and Human Services (HHS)
| US 20240268372 | Uygun et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mustafa Korkut Uygun (Newton, Massachusetts); Siavash Raigani (Cambridge, Massachusetts); Shannon Tessier (Framingham, Massachusetts); Heidi Yeh (Lincoln, Massachusetts); Casie A. Pendexter (Rockland, Massachusetts); Stephanie EJ Cronin (Nashville, Tennessee); Reinier De Vries (Boston, Massachusetts); Mehmet Toner (Charlestown, Massachusetts) |
| ABSTRACT | The present disclosure relates to a perfusate, a storage solution, or a recovery solution having an apoptosis inhibitor. Also disclosed are various uses, including preserving a biological tissue sample and mitigating ischemia-reperfusion injury in such samples. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 18/560000 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) A01N 1/0226 (20130101) Original (OR) Class A01N 1/0284 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240268666 | Patel et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin); Coherence Consulting LLC (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dwani Patel (Milwaukee, Wisconsin); Al Hafeez Dhalla (Durham, North Carolina); Christian B. Viehland (Durham, North Carolina); Daniel M. Lipinski (Milwaukee, Wisconsin) |
| ABSTRACT | Laser-Speckle Contrast imaging apparatus configured to assess and quantify motion associated with an object and, in a specific case of an eye-retinal vascular anatomy and hemodynamics and generate substantially contrast-free maps of retinal blood flow over a wide field-of-view at up to 590 fps and under short exposure durations (>50 μs), is applicable for diagnosis, study, and management of neurodegenerative conditions (i.e. mild cognitive impairment and Alzheimer's disease) and systemic cardiovascular diseases (i.e. athero- and arteriosclerosis, coronary artery occlusion, and hypertension). The apparatus employs a) a set of apertures substantially blocking light, delivered from a source of light to an illumination arm of the apparatus, from impinging onto an axial point of the front surface of the lens of the illumination arm, and b) polarization gating between the illumination and light-collecting arms of the apparatus. In one implementation, the apparatus is configured to allow for irradiation of the object with an optical field a degree of coherence and/or spectral content of which are varied delivered through the same optical train including the set of apertures. |
| FILED | Monday, April 15, 2024 |
| APPL NO | 18/635481 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/1241 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240268672 | Tearney et al. |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Guillermo J. Tearney (Cambridge, Massachusetts); Jiheun Ryu (Cambridge, Massachusetts) |
| ABSTRACT | A method of correcting distortion of an image, including: analyzing, by a processor, an image segment of the image to identify a speckle artifact, the image segment being obtained from a scanning imaging device; determining, by the processor, an aspect ratio of a shape of the speckle artifact; determining, by the processor, a correction factor for the shape of the speckle artifact based on the aspect ratio; and adjusting, by the processor, a dimension of the image segment based on the correction factor. |
| FILED | Monday, April 15, 2024 |
| APPL NO | 18/635232 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) Original (OR) Class A61B 5/7207 (20130101) A61B 5/7275 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4788 (20130101) G01N 2021/479 (20130101) Optical Elements, Systems, or Apparatus G02B 27/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240268698 | DOUSSAN et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
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| INVENTOR(S) | ALLAIRE DOUSSAN (WILDER, Vermont); RYAN HALTER (LYME, New Hampshire); ETHAN MURPHY (WHITE RIVER JUNCTION, Vermont) |
| ABSTRACT | A bioimpedance device for surgical cavities has pick-up electrodes surrounded by driving electrodes, each driving electrode having greater area than the pick-up electrodes, the electrode array coupled through an adjacent connector to an electronics module. The electronics module fits through laparoscopic ports. The electronics module includes a voltage controlled current source, multiplexing for driving electrodes, a force sensor, and voltage buffers, and couples to a data acquisition system coupled to a processor. The processor uses the apparatus to perform bioimpedance mapping of tissue. A method of mapping bioimpedance includes contacting tissue with the electrode array, sequentially driving at least one of the driving electrodes with an alternating current at frequencies between 100 and 1000000 hertz while reading the sense electrodes through analog to digital converters into the processor; using readings of the sense electrodes to generate a bioimpedance map of the tissue; the electrode array fitting through laparoscopic ports. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 18/568940 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0536 (20130101) Original (OR) Class A61B 5/6843 (20130101) A61B 5/7264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240268700 | LIU et al. |
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| APPLICANT(S) | Subtle Medical, Inc. (Menlo Park, California) |
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| INVENTOR(S) | Jiang LIU (Towson, Maryland); Gajanana Keshava DATTA (Los Altos, California); Srivathsa Pasumarthi VENKATA (Sunnyvale, California) |
| ABSTRACT | Methods and systems are provided for synthesizing a contrast-weighted image in Magnetic resonance imaging (MRI). The method comprises: receiving a multi-contrast image of a subject, where the multi-contrast image comprises one or more images of one or more different contrasts; generating an input to a transformer model based at least in part on the multi-contrast image; and generating, by the transformer model, a synthesized image having a target contrast that is different from the one or more different contrasts of the one or more images, where the target contrast is specified in a query received by the transformer model. |
| FILED | Tuesday, April 16, 2024 |
| APPL NO | 18/636423 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/5601 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240268796 | Gaston et al. |
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| APPLICANT(S) | The Trustees of Indiana University (Bloomington, Indiana); Purdue Research Foundation (West Lafayette, Indiana) |
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| INVENTOR(S) | Benjamin Gaston (Indianapolis, Indiana); Nadzeya Marozkina (Indianapolis, Indiana); Noah Neidigh (West Lafayette, Indiana); Alyssa Alexander (West Lafayette, Indiana); Logan Plack (West Lafayette, Indiana); Parker Van Emmerik (West Lafayette, Indiana); Daniel Cater (Zionsville, Indiana) |
| ABSTRACT | Abnormal S-nitrosothiol metabolism is involved in many different diseases, ranging from asthma to septic shock. A critical limitation of current methods for quantifying S-nitrosothiols present in vivo is that samples need to removed be from the body for analysis. The technology of the present disclosure determining S-nitrosothiol levels in situ using ultraviolet light to cleave the S—N bond, releasing the nitric oxide, collecting the nitric oxide, and measuring the nitric oxide. |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/440359 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/7246 (20130101) A61B 5/7282 (20130101) A61B 10/00 (20130101) Original (OR) Class A61B 2010/0083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269093 | Ranum et al. |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Laura Ranum (Gainesville, Florida); Tao Zu (Gainesville, Florida) |
| ABSTRACT | The present disclosure provides the use of compounds of Formulae (I), (II), (III), (III-A), and (III-B) (e.g., metformin) in treating a neurological disease associated with repeat expansions and/or RAN protein accumulation, reducing the level of one or more repeat associated non-ATG (RAN) proteins, and reducing the accumulation of RAN proteins in a subject and/or biological sample. Also provided is the use of compounds of Formulae (I), (II), (III), (III-A), and (III-B) (e.g., metformin) in inhibiting RAN protein translation in a subject and in a biological sample (e.g., cells, tissue). Also provided in the present disclosure are pharmaceutical compositions, kits, and uses of compounds of Formulae (I), (II), (III), (III-A), and (III-B) (e.g., metformin) for treating diseases associated with repeat expansions. Exemplary diseases associated with repeat expansions include, but are not limited to, C9ORFf72 amyotrophic lateral sclerosis (ALS), or C9ORFf72 frontotemporal dementia; myotonic dystrophy type 1 (DM1) and myotonic dystrophy type 2 (DM2); spinocerebellar ataxia; Huntington's disease; Fragile X Tremor Ataxia Syndrome (FXTAS); and Fragile XE syndrome (FRAXE). |
| FILED | Wednesday, January 03, 2024 |
| APPL NO | 18/403100 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/155 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269117 | Kyba et al. |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Michael Kyba (Minneapolis, Minnesota); Darko Bosnakovski (Minneapolis, Minnesota) |
| ABSTRACT | A method for treating a cancer involving one or more translocations generating an oncogenic fusion transcription factor that requires p300/CBP for activity in an animal, comprising administering a compound of formula (I): or a pharmaceutically acceptable salt thereof to the animal. |
| FILED | Wednesday, February 07, 2024 |
| APPL NO | 18/435413 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269128 | Thambisetty et al. |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human (Bethesda, Maryland) |
| INVENTOR(S) | Madhav Thambisetty (Ellicott City, Maryland); Myriam Gorospe (Ellicott City, Maryland); Carlos Anerillas (Baltimore, Maryland) |
| ABSTRACT | A subject is administered an amount of an active agent effective to at least partially normalize an aberrant level of one or more indicators, wherein the indicators comprise extracellular amyloid beta concentration, tau phosphorylation, neuroinflammation, or any combination thereof. The subject may be diagnosed with Alzheimer's disease or may be identified as being at risk of developing Alzheimer's disease. |
| FILED | Thursday, April 04, 2024 |
| APPL NO | 18/627191 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/404 (20130101) A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 31/575 (20130101) A61K 31/4706 (20130101) Original (OR) Class A61K 31/4745 (20130101) A61K 31/7024 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269129 | Jacob et al. |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
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| INVENTOR(S) | Michele Jacob (Medford, Massachusetts); Jonathan Alexander (Medford, Massachusetts); Florence Wagner (Cambridge, Massachusetts); Michel Weiwer (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed are methods and compositions for treating CTNNB1 syndrome. The disclosed methods and compositions may utilize or comprise a glycogen synthase kinase 3 (GSK3) inhibitor, or a pharmaceutically acceptable salt thereof. The GSK3 inhibitor may comprise small molecules such as substituted tricyclic pyrazolo-tetrahydroquinolinones, and the GSK3 inhibitor may selectively inhibit GSK3β and GSK3α or dually inhibit GSK3α and GSK3β. |
| FILED | Friday, March 29, 2024 |
| APPL NO | 18/622123 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4745 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269138 | Park et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jin Mo Park (Newton, Massachusetts); Yanek Jimenez-Andrade (Brighton, Massachusetts) |
| ABSTRACT | Aspects of the present disclosure provide methods for treating allergic inflammatory diseases, such as allergic asthma and atopic dermatitis, using inhibitors of matrix metalloproteinase 13 (MMP13) such as small molecule inhibitors of MMP13. |
| FILED | Tuesday, May 24, 2022 |
| APPL NO | 18/563575 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) Original (OR) Class A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269139 | Gray et al. |
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| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); Korea Institute of Science and Technology (KIST) (Seoul, South Korea) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); Korea Institute of Science and Technology (KIST) (Seoul, South Korea) |
| INVENTOR(S) | Nathanael S. Gray (Boston, Massachusetts); Eric S. Fischer (Chestnut Hill, Massachusetts); Fleur M. Ferguson (Cambridge, Massachusetts); Katherine Donovan (Brookline, Massachusetts); Jonathan W. Bushman (Boston, Massachusetts); Taebo Sim (Seoul, South Korea); Debabrata Bhunia (Hyderabad, India); SeongShick Ryu (Seoul, South Korea) |
| ABSTRACT | The present invention relates to bifunctional compounds for targeted kinase degradation, methods for treating diseases or conditions mediated by aberrant kinase activity, and methods for identifying degradable kinases and optimal kinase:scaffold pairs. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 18/033872 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/4725 (20130101) A61K 31/5025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) G01N 2333/912 (20130101) G01N 2560/00 (20130101) G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269144 | CHEN et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pei-Ling CHEN (Tampa, Florida); Xiaofei SONG (Tampa, Florida) |
| ABSTRACT | Disclosed novel expression and mutation patterns that correlate with the presence of a malignancy in B and T cell cancers. Accordingly, disclosed herein are kits and methods for the diagnosis of cancer malignancies. |
| FILED | Thursday, June 02, 2022 |
| APPL NO | 18/566277 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) A61K 31/454 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/5415 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269149 | ADAMS et al. |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (IOWA CITY, Iowa); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (WASHINGTON, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (IOWA CITY, Iowa); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (WASHINGTON, District of Columbia) |
| INVENTOR(S) | Christopher M. ADAMS (Rochester, Minnesota); Steven D. KUNKEL (West Richland, Washington); Michael WELSH (Riverside, Iowa) |
| ABSTRACT | The invention provides a method for (a) increasing skeletal muscle mass; (b) reducing skeletal muscle atrophy; (c) increasing muscular strength; (d) promoting muscle growth; (e) decreasing muscle wasting; or (f) increasing strength per unit of muscle mass in an animal identified or having been identified to be in need of one or more of (a)-(f), the method comprising administering to the animal an effective amount of a compound of formula: or a stereoisomer, solvate, or pharmaceutically acceptable salt thereof, thereby accomplishing one or more of (a)-(f). |
| FILED | Tuesday, August 22, 2023 |
| APPL NO | 18/454012 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 31/56 (20130101) A61K 31/58 (20130101) Original (OR) Class A61K 31/215 (20130101) A61K 31/352 (20130101) A61K 31/353 (20130101) A61K 31/382 (20130101) A61K 31/404 (20130101) A61K 31/407 (20130101) A61K 31/435 (20130101) A61K 31/436 (20130101) A61K 31/437 (20130101) A61K 31/438 (20130101) A61K 31/473 (20130101) A61K 31/565 (20130101) A61K 31/4164 (20130101) A61K 31/4166 (20130101) A61K 31/4355 (20130101) A61K 31/4365 (20130101) A61K 31/4375 (20130101) A61K 31/4706 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 2600/136 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 2800/10 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269158 | MORICI-EMBERS |
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| APPLICANT(S) | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana) |
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| INVENTOR(S) | Monica E. MORICI-EMBERS (Mandeville, Louisiana) |
| ABSTRACT | Disclosed herein are therapeutic agents and combinations of therapeutic agents for use in the treatment of bacterial diseases. Such therapeutic agents and combinations may include azlocillin. Methods of reducing or inhibiting Bartonella bacteria in cells and/or in subjects having Bartonella infections and related disorders by providing therapeutic agents alone or in combination are provided. |
| FILED | Thursday, June 02, 2022 |
| APPL NO | 18/566383 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/431 (20130101) A61K 31/7052 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269163 | KENT et al. |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas); The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); The Trustees of Indiana University (Bloomington, Indiana) |
| INVENTOR(S) | Thomas A. KENT (Houston, Texas); Paul J. DERRY (Houston, Texas); Kenneth R. OLSON (Berrien Springs, Michigan) |
| ABSTRACT | A method of treating a Down syndrome (DS) subject with functional or at risk of decline of organ systems associated with accelerated aging due to over-production of H2S is disclosed. That method contemplates administering a pharmaceutical composition containing a H2S-reducing effective amount of hydrophilic polymer-substituted oxidized carbon nanoparticles (OCNPs) and an optional potentiating amount of lipoic acid or dihydrolipoic acid dissolved or dispersed in a physiologically acceptable diluent to the subject. The pharmaceutical composition can be administered parenterally as a liquid or per os as a solid or liquid. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 18/567972 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/385 (20130101) A61K 31/765 (20130101) Original (OR) Class A61K 47/6921 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269179 | Velculescu et al. |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victor E. Velculescu (Dayton, Maryland); Valsamo Anagnostou (Baltimore, Maryland) |
| ABSTRACT | Disclosed are methods of identifying target epitopes for a tumor of an individual using massively parallel sequencing and analyzing mutant epitopes. Also disclosed are methods of treating a tumor in an individual. Also disclosed are personalized, anti-tumor immunogenic preparations (e.g., personalized, anti-tumor chimeric antigen receptors (CAR) or chimeric antigen receptor T cell (CAR T cell)) customized for an individual cancer patient who initially responded to anti-tumor therapy and later became resistant to the therapy. |
| FILED | Thursday, September 14, 2023 |
| APPL NO | 18/466966 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 39/39 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/70539 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6869 (20130101) C12Q 1/6881 (20130101) C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56977 (20130101) G01N 33/57484 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269187 | Fletcher et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation d/b/a Massachusetts General Hospital (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation d/b/a Massachusetts General Hospital (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Anne Fletcher (Oakleigh South, Australia); Shannon J. Turley (San Anselmo, California); Biju Parekkadan (Cambridge, Massachusetts) |
| ABSTRACT | A method for suppressing an immune response is provided. The method involves administration of isolated lymphoid tissue-derived suppressive stromal cells (LSSC) to a subject in need of such treatment in an amount effective to suppress the immune response in the subject. The invention also involves a method to isolate LSSC by digesting lymphoid tissue fragments using a combination of an enzyme mix and agitation and then collecting the LSSC. Pharmaceutical preparations comprising LSSC are also provided. |
| FILED | Friday, April 05, 2024 |
| APPL NO | 18/628251 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/26 (20130101) Original (OR) Class A61K 38/19 (20130101) A61K 38/204 (20130101) A61K 38/1866 (20130101) A61K 2035/122 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0651 (20130101) C12N 5/0669 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269188 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Yufang Shi (Belle Mead, New Jersey); Guangwen Ren (Bar Harbor, Maine); Liying Zhang (Belle Mead, New Jersey) |
| ABSTRACT | The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs). |
| FILED | Wednesday, December 20, 2023 |
| APPL NO | 18/390569 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 38/20 (20130101) A61K 38/191 (20130101) A61K 38/212 (20130101) A61K 38/215 (20130101) A61K 38/217 (20130101) A61K 38/1825 (20130101) A61K 38/1841 (20130101) A61K 38/2006 (20130101) A61K 45/06 (20130101) A61K 2035/122 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) A61P 37/04 (20180101) A61P 37/06 (20180101) Peptides C07K 14/50 (20130101) C07K 14/52 (20130101) C07K 14/56 (20130101) C07K 14/57 (20130101) C07K 14/495 (20130101) C07K 14/525 (20130101) C07K 14/545 (20130101) C07K 14/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0607 (20130101) C12N 5/0662 (20130101) C12N 5/0663 (20130101) C12N 5/0665 (20130101) C12N 2500/05 (20130101) C12N 2501/10 (20130101) C12N 2501/15 (20130101) C12N 2501/24 (20130101) C12N 2501/25 (20130101) C12N 2501/115 (20130101) C12N 2501/2301 (20130101) C12N 2501/2317 (20130101) C12N 2502/1114 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269190 | SMITH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (PHILADELPHIA, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | LACHLAN JAMES SMITH (Philadelphia, Pennsylvania); CHENGHAO ZHANG (Philadelphia, Pennsylvania) |
| ABSTRACT | Described are compositions containing isolated mammalian nucleus pulposus cells having an extracellular matrix (ECM)-generating phenotype and methods for making and using the disclosed compositions. The compositions disclosed herein are useful for treating back pain. |
| FILED | Tuesday, January 23, 2024 |
| APPL NO | 18/420721 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269199 | Aroian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raffi Van Aroian (Shrewsbury, Massachusetts); Kelly Flanagan (Boston, Massachusetts) |
| ABSTRACT | Compositions and methods for treating or reducing the severity or likelihood of occurrence of a parasitic worm infection in a humans and domestic animals are described. The compositions include inactivated recombinant bacteria expressing a Cry14Ab crystal protein in the cytosol of the bacterium. The composition may be provided in a form suitable for oral administration. Methods include administering a therapeutically effective amount of the composition to a human or domestic animal suffering from a parasitic worm infection. The composition may also be used as feed, feed supplement, or a waste treatment. |
| FILED | Wednesday, January 17, 2024 |
| APPL NO | 18/415118 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5089 (20130101) A61K 35/742 (20130101) Original (OR) Class A61K 38/164 (20130101) A61K 2035/115 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269228 | Gajewiak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joanna Gajewiak (Salt Lake City, Utah); Joseph Michael McIntosh (Salt Lake City, Utah) |
| ABSTRACT | Disclosed herein are compositions and methods related to RgIA4 peptide analogs. An RgIA4 peptide analog can comprise a recognition finger region configured to bind to an α9α10 nicotinic acetylcholine receptor. The RgIA4 peptide analog can comprise at least two disulfide bridges comprising: an inter-cysteine disulfide bridge between a first cysteine and a second cysteine, and a penicillamine-cysteine disulfide bridge between a first penicillamine and a third cysteine. The RgIA4 peptide analog can have a binding affinity for the α9α10 nicotinic acetylcholine receptor that is at least 50% of a binding affinity of an RgIA4 peptide. A method of maintaining an RgIA4 peptide potency for an α9α10 nicotinic acetylcholine receptor in an RgIA4 peptide analog can comprise providing a composition as disclosed herein. A method for treating a condition responsive to α9α10 nicotinic acetylcholine receptor binding can comprise administering a therapeutically effective amount of the composition to the subject. |
| FILED | Wednesday, March 16, 2022 |
| APPL NO | 18/567010 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Peptides C07K 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269242 | Ledford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); RAESEDO, LLC (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julie Ledford (Tucson, Arizona); Monica Kraft (New York, New York); Josef Vagner (Tucson, Arizona) |
| ABSTRACT | Provided herein are compositions and methods for treating and preventing lung disease. In particular, provided herein are SP-A peptides and uses thereof in the treatment and prevention of lung disease (e.g., asthma or COPD). The compositions may comprise peptides having an amino acid sequence of Ac-WGKEQCVE(Nle)(Pego3)-Hdc (SEQ ID NO: 24) The peptide compositions may also be used to treat COVID-19. |
| FILED | Friday, February 23, 2024 |
| APPL NO | 18/586133 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/395 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) A61P 31/14 (20180101) Peptides C07K 14/785 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269252 | Shah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Nisarg J. Shah (San Diego, California); Ting-Yu Shih (Brookline, Massachusetts); Angelo S. Mao (Cambridge, Massachusetts); David J. Mooney (Cambridge, Massachusetts); David T. Scadden (Weston, Massachusetts) |
| ABSTRACT | Acute myeloid leukemia (AML) is a clonal disorder of hematopoietic stem and progenitor cells. It is a devastating disease with a poor prognosis and an average 5-year survival rate of about 30%. Disclosed herein are composition and methods for treating leukemia with a biomaterial comprising a polymer scaffold, a dendritic cell activating factor, a dendritic cell recruitment factor, and at least one leukemia antigen. The biomaterial-based vaccine disclosed herein promotes a potent, durable and transferable immune response against acute myeloid leukemia to prevent cell engraftment and synergizes with chemotherapy to prevent relapse. |
| FILED | Monday, December 18, 2023 |
| APPL NO | 18/544197 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/7068 (20130101) A61K 39/39 (20130101) A61K 39/001153 (20180801) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/572 (20130101) A61K 2039/804 (20180801) A61K 2039/6087 (20130101) A61K 2039/6093 (20130101) A61K 2039/55561 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269256 | Erasmus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HDT Bio Corp. (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jesse Hong-Sae Erasmus (Port Orchard, Washington); Jacob Freeman Archer (Seattle, Washington) |
| ABSTRACT | The disclosure provides nanoparticle and compound compositions and methods of making and using the same to a nucleic acid encoding a protein, antibody, or functional fragment thereof for administration to a subject. Various nanoparticle carriers are described. In some instances, the nanoparticle component may include a hydrophobic core having an inorganic particle, and optionally a membrane having a cationic lipid. |
| FILED | Thursday, March 21, 2024 |
| APPL NO | 18/612850 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/125 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/127 (20130101) C12N 15/88 (20130101) C12N 2770/32322 (20130101) Enzymes C12Y 207/07048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269257 | Amanna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Najít Technologies, Inc. (Beaverton, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ian J. Amanna (Hillsboro, Oregon); Elizabeth A. Poore (Portland, Oregon) |
| ABSTRACT | Provided are methods for rapidly inactivating a pathogen, or for producing a vaccine composition containing an inactivated noninfectious pathogen having retained antigenicity and/or immunogenicity, comprising exposing the pathogen to a chemical inactivating agent (e.g., one or more chemical oxidizing, alkylating or crosslinking agents) in the presence of inorganic polyatomic oxyanions in an amount and for a time sufficient to render the pathogen noninfectious while enhancing retention of pathogen antigenicity and/or immunogenicity relative to that retained by contacting the pathogen with the chemical inactivating agent alone. The methods are broadly applicable to pathogens having RNA or DNA genomes (e.g., including viruses, bacteria, fungi, and parasites). Also provided are vaccine compositions (medicaments) containing a pathogen inactivated by exposure to an inactivating agent in the presence of elevated concentrations of inorganic polyatomic oxyanions, and methods for eliciting an immune response in a subject by administering the vaccine compositions. |
| FILED | Thursday, November 02, 2023 |
| APPL NO | 18/500970 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/40 (20130101) A61K 39/02 (20130101) A61K 39/12 (20130101) A61K 39/105 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 39/275 (20130101) A61K 39/0283 (20130101) A61K 2039/521 (20130101) A61K 2039/5252 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 31/16 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16131 (20130101) C12N 2760/16134 (20130101) C12N 2760/16163 (20130101) C12N 2760/16171 (20130101) C12N 2770/24134 (20130101) C12N 2770/24163 (20130101) C12N 2770/24171 (20130101) C12N 2770/36134 (20130101) C12N 2770/36163 (20130101) C12N 2770/36171 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269266 | BenMohamed |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lbachir BenMohamed (Irvine, California) |
| ABSTRACT | Waning immunity induced by first-generation Spike-alone-based COVID-19 has failed to prevent immune escape by many variants of concern (VOCs) that emerged from 2020 to 2024, resulting in a prolonged COVID-19 pandemic. Thus, a next-generation Coronavirus (CoV) vaccine incorporating highly conserved non-Spike SARS-CoV-2 antigens is described herein. Conserved non-Spike T cell antigens in combination with a Spike antigen encapsulated in lipid nanoparticles: (i) Induced high frequencies of lung-resident antigen-specific CXCR5+CD4+ T follicular helper cells, GzmB+CD4+ and GzmB+CD8+ cytotoxic T cells, and CD69+IFN-γ+TNFα+CD4+ and CD69+IFN-γ+TNFα+CD8+ effector T cells; and (ii) Reduced viral load and COVID-19-like symptoms caused by various VOCs. The combined antigen/LNP-based pan-CoV vaccine could be rapidly adapted for clinical use to confer broader cross-protective immunity against emerging highly mutated and pathogenic VOCs. |
| FILED | Monday, March 11, 2024 |
| APPL NO | 18/601925 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Original (OR) Class A61K 39/295 (20130101) A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/55555 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2770/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269269 | Lynn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Barinthus Biotherapeutics North America, Inc. (Germantown, Maryland); The United States of America, as represented by the Secretary, Department of Health (Bethesda, Maryland) |
| ASSIGNEE(S) | Vaccitech North America, Inc. (Germantown, Maryland); The United States of America, as represented by the Secretary, Department of Health (Bethesda, Maryland) |
| INVENTOR(S) | Geoffrey Martin Lynn (Baltimore, Maryland); Christopher Martin O’Brien Garliss (Baltimore, Maryland); Andrew Scott Ishizuka (Washington, District of Columbia); Hugh Clarke Welles (Baltimore, Maryland) |
| ABSTRACT | The present disclosure relates to a vaccine comprising at least one peptide antigen conjugate having the formula selected from PEG-[E1]-A-[E2]-[U]—H and H—[U]-[E1]-A-[E2]-PEG, wherein E1 is an N terminal extension, E2 is a C terminal extension, A is peptide antigen, H is hydrobhobic block, wherein one or more drug molecules (D) are optionally attached to each H directly or via a suitable linker X1; U is a linker, [ ] denotes the group is optional and - denotes that the two adjacent groups are directly attached to one another by a covalent bond or indirectly to one another via a suitable linker X. The vaccine is useful in treating or preventing a cancer, an autoimmune disease, an allergy, or an infectious disease. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/494491 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/35 (20130101) A61K 39/385 (20130101) Original (OR) Class A61K 47/545 (20170801) A61K 47/549 (20170801) A61K 47/646 (20170801) A61K 47/6935 (20170801) A61K 2039/54 (20130101) A61K 2039/577 (20130101) A61K 2039/6093 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269270 | ANOSOVA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SANOFI PASTEUR INC. (Swiftwater, Pennsylvania); GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| ASSIGNEE(S) | SANOFI PASTEUR INC. (Swiftwater, Pennsylvania); GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| INVENTOR(S) | Natalie ANOSOVA (Lexington, Massachusetts); Salvador Fernando AUSAR (Markham, Canada); Catherine BERRY (Lyon, France); Florence BOUDET (Lyon, France); Thomas BREUER (Wavre, Belgium); Danilo CASIMIRO (Harleysville, Pennsylvania); Roman M. CHICZ (Belmont, Massachusetts); Gustavo DAYAN (Bethlehem, Pennsylvania); Guy DE BRUYN (Bushkill Township, Pennsylvania); Carlos DIAZGRANADOS (Wind Gap, Pennsylvania); Tong-Ming FU (Philadelphia, Pennsylvania); Marie GARINOT (Lyon, France); Lorry GRADY (Simsbury, Connecticut); Sanjay GURUNATHAN (Bethlehem, Pennsylvania); Kirill KALNIN (Pelham, New Hampshire); Nikolai KHRAMTSOV (Branford, Connecticut); Valérie LECOUTURIER (Chazay d'Azergues, France); Nausheen RAHMAN (North York, Canada); Sophie RUIZ (Lyon, France); Stephen SAVARINO (Saylorsburg, Pennsylvania); Saranya SRIDHAR (London, United Kingdom); Indresh K. SRIVASTAVA (Marlborough, Connecticut); James TARTAGLIA (Nazareth, Pennsylvania); Timothy TIBBITTS (East Greenwich, Rhode Island) |
| ABSTRACT | Provided are novel vaccines for prophylactic treatment of SARS-COV-2 infections and COVID-19 and methods of making the vaccines, wherein the vaccines contain an oil-in-water emulsion comprising tocopherol and squalene. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 18/042637 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 39/215 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/55566 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0601 (20130101) C12N 7/00 (20130101) C12N 2770/20022 (20130101) C12N 2770/20034 (20130101) C12N 2770/20071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269286 | Horsager et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EOS Neuroscience, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan Horsager (Los Angeles, California); Kenneth Greenberg (Oakland, California); Benjamin C. Matteo (San Francisco, California); Edward S. Boyden (Chestnut Hill, Massachusetts); Douglas G. Ririe (Winston-Salem, North Carolina); James C. Eisenach (Winston-Salem, North Carolina); Christian Wentz (Cambridge, Massachusetts) |
| ABSTRACT | Provided are compositions and methods for the selective silencing of neurons in pain pathway by using a combination of inhibitory light-sensitive protein gene transfer and wavelength specific illumination. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/454275 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 41/00 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Peptides C07K 14/37 (20130101) C07K 14/195 (20130101) C07K 14/215 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14143 (20130101) C12N 2810/6027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269294 | Karsenty et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York); William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gerard Karsenty (New York, New York); Julian Berger (New York, New York); Han Xiao (Houston, Texas) |
| ABSTRACT | Methods for treating muscle loss and exercise capacity pathologies by controlling osteocalcin release, and compositions therefor, are provided. |
| FILED | Tuesday, April 09, 2024 |
| APPL NO | 18/630263 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/545 (20170801) A61K 47/548 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269303 | HOWELL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Development Foundation (Carson City, Nevada) |
| ASSIGNEE(S) | Research Development Foundation (Carson City, Nevada) |
| INVENTOR(S) | Stephen HOWELL (La Jolla, California); Maria Carmen MULERO ROIG (South San Francisco, California); Dennis P. GATELY (South San Francisco, California) |
| ABSTRACT | Cell-targeted cytotoxic compounds are provided herein. Such compounds can be used, e.g., to selectively bind and kill cancer cells such as cancer stem cells that express LGR4, LGR5, or LGR6. In some embodiments, the cytotoxic compounds include an LGR binding polypeptide, a cytotoxic agent (e.g., MMAE), and an Fc region (e.g., a mutant Fc domain). Methods for using the compounds to treat cell proliferative diseases such as cancers are also provided. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/494052 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/64 (20170801) A61K 47/68 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269336 | Bahremand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alireza BAHREMAND (Masa, Arizona); Richard GERKIN (Tempe, Arizona); Mason MANETTA (Mesa, Arizona); Jessica LAI (Tempe, Arizona); Robert LIKAMWA (Tempe, Arizona); Brian SMITH (Phoenix, Arizona); Christy SPACKMAN (Phoenix, Arizona); ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alireza Bahremand (Mese, Arizona); Richard Gerkin (Tempe, Arizona); Mason Manetta (Mesa, Arizona); Jessica Lai (Tempe, Arizona); Robert LiKamWa (Temp, Arizona); Brian Smith (Phoenix, Arizona); Christy Spackman (Phoenix, Arizona) |
| ABSTRACT | Described herein are systems, methods, and apparatuses for implementing olfactory delivery in virtualized environments using an olfactory delivery engine. Mimicking physical odor sensations virtually can present users with a real-time odor synthesis that approximates what users would smell in a virtual environment, e.g., as they walk around in virtual reality. A novel Smell Engine is described herein which includes: (i) a Smell Composer framework that allows developers to configure odor sources in virtual space, (ii) a Smell Mixer that dynamically estimates the odor mix that the user would smell, based on diffusion models and relative odor source distances, and (iii) a Smell Controller that coordinates an olfactometer to physically present an approximation of the odor mix to the user's mask from a set of odorants channeled through controllable flow valves. Experimental results show that the Smell Engine can help measure a subject's olfactory detection threshold and improve their ability to precisely localize odors in the virtual environment, as compared to existing trigger-based solutions. Other related embodiments are disclosed. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 18/553089 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 9/125 (20130101) Original (OR) Class A61L 2209/11 (20130101) A61L 2209/134 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/02 (20130101) A61M 2021/005 (20130101) A61M 2021/0016 (20130101) Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/28 (20140902) Systems for Controlling or Regulating Non-electric Variables G05D 11/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269339 | PERRY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRICOL BIOMEDICAL, INC. (Portland, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenneth E. PERRY (Bainbridge Island, Washington); Kenneth P. PERRY (Bainbridge Island, Washington); MacKayla CAROLAN (Portland, Oregon); Madison BUTLER (Portland, Oregon); Shalini GAUTAM (Hillsboro, Oregon); Simon John MCCARTHY (Portland, Oregon) |
| ABSTRACT | The present invention relates to a dissolution resistant, biocompatible, foldable, thin profile, low mass and high surface area, chitosan dressing, optionally modified with iron, and suitable for treating bleeding in a physiological environment, e.g. gastrointestinal tract. The characteristics and structures of the chitosan dressing are provided. Devices and systems for delivery of dressing to a target tissue site are provided. Methods of making and using the chitosan dressing are also provided. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 18/568202 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 15/005 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/28 (20130101) Original (OR) Class A61L 15/44 (20130101) A61L 15/58 (20130101) A61L 15/425 (20130101) A61L 2400/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269348 | Cullen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); John C. O'Donnell (Bryn Mawr, Pennsylvania); Erin M. Purvis (Philadelphia, Pennsylvania); Anh Le (Philadelphia, Pennsylvania); Qunzhou Zhang (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided herein is a method of obtaining astrocytes from gingiva-derived mesenchymal stem cells (GDMSC). Also disclosed herein are systems comprising a biocompatible construct and a plurality of astrocytes obtained from a method disclosed herein and methods of making and using the same. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 18/566373 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3604 (20130101) A61L 27/3675 (20130101) A61L 27/3895 (20130101) Original (OR) Class A61L 2430/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) C12N 2501/11 (20130101) C12N 2501/115 (20130101) C12N 2501/135 (20130101) C12N 2506/1392 (20130101) C12N 2533/54 (20130101) C12N 2533/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269351 | Reddy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sashank Reddy (Baltimore, Maryland); Russell Martin (Baltimore, Maryland); Xiaowei Li (Townson, Maryland); Calvin Chang (Baltimore, Maryland); Kevin Colbert (Baltimore, Maryland); Hai-Quan Mao (Baltimore, Maryland) |
| ABSTRACT | A soft tissue device can incorporate a composite material comprising a gel and at least one nanostructure disposed within the gel. A soft tissue device can further incorporate biologically active materials such as cells, tissues. A method for healing a soft tissue defect while promoting soft tissue regeneration can include applying a soft tissue device to a soft tissue defect, wherein the composite material includes a gel and a nanostructure disposed within the gel. A method for manufacturing a soft tissue device for use in healing soft tissue defects can include providing a gel, disposing nanofibers within the gel, and a biologically active material. |
| FILED | Thursday, August 24, 2023 |
| APPL NO | 18/237744 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/20 (20130101) A61L 27/44 (20130101) A61L 27/48 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) Original (OR) Class A61L 27/3808 (20130101) A61L 27/3834 (20130101) A61L 27/3895 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2300/602 (20130101) A61L 2300/604 (20130101) A61L 2300/622 (20130101) A61L 2400/06 (20130101) A61L 2400/12 (20130101) A61L 2430/34 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/19 (20130101) A61M 2202/08 (20130101) A61M 2202/09 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269352 | Rao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siyuan Rao (Sunderland, Massachusetts); Sizhe Huang (Amherst, Massachusetts); Qianbin Wang (Sunderland, Massachusetts); Kayla Felix (Taunton, Massachusetts); Collin Maley (Medway, Massachusetts) |
| ABSTRACT | A miniaturized hydrogel includes a reaction product of a hydroxyl-containing polymer, a primary crosslinker, and a secondary crosslinker, and water. The primary crosslinker and the secondary crosslinker are capable of reacting with the hydroxyl-containing polymer. The hydrogel is made by a method including contacting the hydroxyl-containing polymer, the primary crosslinker, and the secondary crosslinker under conditions effective to provide a crosslinked hydrogel; acidifying the crosslinked hydrogel; drying the crosslinked hydrogel under tension; and rehydrating the dried hydrogel to provide the miniaturized hydrogel. The miniaturized hydrogel can be particularly useful in various implantable medical devices. |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/440095 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/048 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269463 | Yoshida et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenichi Yoshida (Carmel, Indiana); Michael Ryne Horn (Fishers, Indiana); Awadh Al Hawwash (Indianapolis, Indiana); Nathaniel Lazorchak (Indianapolis, Indiana); Christian Phillip Vetter (Lombard, Illinois); Onna Marie Doering (Indianapolis, Indiana) |
| ABSTRACT | Nerve stimulation via a Low Frequency Alternating Current (LFAC) waveform can result in blocking of action potential conduction, while an increase in LFAC frequency and/or amplitude can translate into nerve activation. As LFAC for nerve blocking is frequency independent, the threshold LFAC activation can decrease with increasing frequency. Thus, frequency and amplitude settings can determine whether LFAC activates or blocks nerve fibers. LFAC can also be orderly, wherein smaller, non-fatiguing nerve fibers can be activated before larger nerve fibers. LFAC settings for activation can also be influenced by the configuration of a cuff assembly that positions an electrode along a nerve. The cuff can position a nerve in a cuff through hole, and a sliding closure of the cuff can be slide into a radial opening to substantially lock the nerve in the cuff assembly. An electrode material is positioned within a window of the cuff and is connected to an electrical lead. An interface coating on a nerve-facing bioelectric surface of an electrode material, and related compositions and methods, are also provided. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 18/691874 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0556 (20130101) Original (OR) Class A61N 1/36053 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269468 | EDGERTON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California); University of Louisville Research Foundation, Inc. (Louisville, Kentucky); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victor Reggie EDGERTON (Los Angeles, California); Roland R. ROY (Playa Vista, California); Yury GERASIMENKO (Los Angeles, California); Joel W. BURDICK (Pasadena, California); Susan J. HARKEMA (Louisville, Kentucky); Jonathan HODES (Louisville, Kentucky); Yu-Chong TAI (Pasadena, California); Mandheerej S. NANDRA (Pasadena, California); Claudia A. ANGELI (Louisville, Kentucky); Thomas Anthony DESAUTELS (Pasadena, California) |
| ABSTRACT | A system and methods are disclosed for enabling or improving control of cardiovascular and/or vasomotor autonomic functions in a patient having a neurologically derived paralysis or a nervous system disorder. |
| FILED | Monday, April 15, 2024 |
| APPL NO | 18/635518 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0237 (20130101) A61H 1/0274 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/0553 (20130101) A61N 1/0556 (20130101) A61N 1/3616 (20130101) A61N 1/36003 (20130101) A61N 1/36103 (20130101) Original (OR) Class Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/00181 (20130101) A63B 22/0235 (20130101) A63B 69/0064 (20130101) A63B 2213/004 (20130101) A63B 2220/805 (20130101) A63B 2230/60 (20130101) Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2270/0421 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269473 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois); THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John A. Rogers (Wilmette, Illinois); Yeonsik Choi (Evanston, Illinois); Igor Efimov (Washington, District of Columbia); Rose T. Yin (Washington, District of Columbia) |
| ABSTRACT | A device implantable on a target of interest of a subject for pacemaker, neuromodulator, and/or defibrillator therapy comprises a wireless power harvesting unit configured to deliver power via resonant inductive coupling to the target tissue for stimulation in a manner that eliminates need for batteries and allows for externalized control without transcutaneous leads. The device relies exclusively on materials that resorb when exposed to biofluids in a time-controlled manner via metabolic action and hydrolysis. The materials and design choices create a thin, flexible, and lightweight form that maintain excellent biocompatibility and stable function throughout a desired period of use. Over a subsequent timeframe following the completion of therapy, the devices disappear completely through natural biological processes. These characteristics and a miniaturized geometry facilitate full implantation into the body to eliminate the need for percutaneous hardware, which thereby minimizes the risk of device-associated infections and dislodgement. |
| FILED | Monday, June 27, 2022 |
| APPL NO | 18/569649 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/10 (20130101) A61L 31/022 (20130101) A61L 31/148 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/025 (20130101) A61N 1/059 (20130101) A61N 1/362 (20130101) A61N 1/0595 (20130101) A61N 1/3756 (20130101) A61N 1/3758 (20130101) A61N 1/3787 (20130101) A61N 1/37229 (20130101) Original (OR) Class A61N 1/37512 (20170801) A61N 1/39622 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269484 | Berbeco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ross Berbeco (Cambridge, Massachusetts); Matthew Jacobson (Natick, Massachusetts); Thomas Harris (Brookline, Massachusetts) |
| ABSTRACT | A method is provided for delivering radiation therapy to a patient. The method can include receiving a radiation treatment plan for the patient, receiving first imaging data, the first imaging data can be a dual-energy imaging acquisition, delivering a radiation therapy beam to a patient, receiving, from a portal imaging system, second imaging data, the portal imaging system can sense the radiation therapy beam to acquire the second imaging data, and compensating for movement of the patient, based on the first imaging data and the second imaging data. |
| FILED | Thursday, May 26, 2022 |
| APPL NO | 18/563276 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1037 (20130101) A61N 5/1049 (20130101) Original (OR) Class A61N 5/1071 (20130101) A61N 5/1081 (20130101) A61N 2005/1054 (20130101) A61N 2005/1061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269491 | XU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhen XU (Ann Arbor, Michigan); Jonathan Robert SUKOVICH (Ann Arbor, Michigan); Timothy Lewis HALL (Ann Arbor, Michigan) |
| ABSTRACT | An all-in-one ultrasound therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious ultrasound therapy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures. The ultrasound therapy can include modalities such as histotripsy, hyperthermia/radio-sensitization, HIFU microbubble-enhanced drug delivery, immunotherapy, sonodynamic therapy, and/or neuromodulation. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 18/568045 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) Original (OR) Class A61N 2007/0026 (20130101) A61N 2007/0039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269636 | LEE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daeyeon LEE (Wynnewood, Pennsylvania); David Aaron ISSADORE (Philadelphia, Pennsylvania); Jingyu WU (Philadelphia, Pennsylvania); Sagar Prasad YADAVALI (Downington, Pennsylvania) |
| ABSTRACT | Hydrogel particles (microgels) generated using microfluidic methods have superb properties such as high size uniformity and precise control over degradation and release profiles, making them useful for applications in wound healing and injectable drug delivery. However, the throughput of microfluidics is constrained by the physics governing the flow of immiscible fluids confined within microchannels. This throughput tends to be several orders of magnitude lower than what would be necessary for commercial and clinical applications. Here, we demonstrate the scaling up of on-chip synthesis of microgels by parallelizing the microfluidic channels. Taking advantage of the established fabrication technologies developed by the semiconductor industry and a high flow control system, a 4-inch silicon microfluidic chip integrating more than 4,000 microfluidic devices is developed. By incorporating a high energy flood UV source, this chip allows the synthesis of poly (ethylene glycol) diacrylate microgel particles with diameter down to 30 m at a throughput above Ikg/hr. By using photomasks that enable milli-second scale control of the UV exposure, the stiffness of microgels can be varied. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 18/569403 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0052 (20130101) Original (OR) Class B01J 19/0093 (20130101) B01J 2219/00792 (20130101) B01J 2219/00936 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269668 | Maingi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Vishal Maingi (Altadena, California) |
| ABSTRACT | Systems and methods for assessment of lipid membrane-associated molecules are described. Generally, a system can comprise a scaffold with a molecule attached thereon. The scaffold can comprise a plurality of hydrophobic seeds to form a liposome. The molecule attached to the scaffold can integrate into the formed liposome and then be released from the scaffold. The kinetics, dynamics, and interactions of the molecule within the liposome can be detected or monitored. |
| FILED | Thursday, October 12, 2023 |
| APPL NO | 18/486054 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) Original (OR) Class B01L 2200/02 (20130101) B01L 2300/0832 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/92 (20130101) G01N 2333/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270762 | BURNS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Venatorx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher J. BURNS (Malvern, Pennsylvania); Denis DAIGLE (Street, Maryland); Guo-Hua CHU (Exton, Pennsylvania); Jodie HAMRICK (New Holland, Pennsylvania); Steven A. BOYD (Chester Springs, Pennsylvania); Allison L. ZULLI (Chesterbrook, Pennsylvania); Stephen M. CONDON (Glenmoore, Pennsylvania); Cullen L. MYERS (Phoenixville, Pennsylvania); Zhenrong XU (Chalfont, Pennsylvania); Tsuyoshi UEHARA (Berwyn, Pennsylvania); Nathan LINE (Royersford, Pennsylvania) |
| ABSTRACT | Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections. |
| FILED | Friday, March 25, 2022 |
| APPL NO | 18/563292 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/2013 (20130101) A61K 9/2018 (20130101) A61K 9/2054 (20130101) A61K 9/2059 (20130101) A61K 9/4825 (20130101) A61K 9/4858 (20130101) A61K 31/69 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class C07F 9/6596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270802 | ROYBAL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kole ROYBAL (San Francisco, California); Julie GARCIA (San Francisco, California); Iowis ZHU (San Francisco, California); Jaehyuk CHOI (Chicago, Illinois); Jay DANIELS (Chicago, Illinois) |
| ABSTRACT | The present disclosure relates generally to compositions and methods for improving T cell therapy. In particular, the disclosure provides polypeptides and recombinant nucleic acid constructs and/or recombinant nucleic acids encoding polypeptides having mutations capable of altering T cell signaling, cytokine production, and/or in vivo persistence in tumors of therapeutic T cells comprising the mutation. The T cell signaling can be by NFAT, NF-κB and/or AP-1 pathways. The disclosure also provides vectors and cells including the polypeptides and/or recombinant nucleic acid constructs and/or recombinant nucleic acids of the disclosure as well as methods of preparing a T cell for use in cell therapy, and methods of identifying a mutation useful for improving T cell therapy. |
| FILED | Tuesday, April 09, 2024 |
| APPL NO | 18/630828 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4632 (20230501) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4702 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270804 | KAPILOFF et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cardiac RSK3 Inhibitors, LLC (Los Altos, California) |
| ASSIGNEE(S) | Cardiac RSK3 Inhibitors, LLC (Los Altos, California) |
| INVENTOR(S) | Michael S. KAPILOFF (Los Altos, California); Federico Cividini (Belmont, California) |
| ABSTRACT | The present invention describes a novel gene regulatory sequence containing promoter and enhancer sequences of the human cardiac troponin T gene (TNNT2) that directs expression selectively in the cardiac myocyte. The new TNNT2 promoter/enhancer composition can be used to direct adeno-associated virus gene expression or to construct cell-type specific expression vectors or for cardiac specific transgenesis. The use of this new promoter/enhancer composition is demonstrated by expression of an mAKAP shRNA and mAKAP-derived anchoring disruptor peptides useful for the treatment of heart failure. |
| FILED | Monday, February 12, 2024 |
| APPL NO | 18/439546 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0025 (20130101) Peptides C07K 14/4716 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270808 | BURNETT, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
| ASSIGNEE(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
| INVENTOR(S) | John C. BURNETT, Jr. (Rochester, Minnesota) |
| ABSTRACT | Analogues of an alternatively spliced form of atrial natriuretic peptide (MANP) that exhibit pGC-A gain of function and can be used to treat cardiorenal and metabolic disease are described herein. |
| FILED | Thursday, January 04, 2024 |
| APPL NO | 18/404131 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/12 (20180101) A61P 13/12 (20180101) Peptides C07K 14/58 (20130101) Original (OR) Class C07K 14/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270814 | Deniger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| INVENTOR(S) | Drew C. Deniger (Houston, Texas); Steven A. Rosenberg (Potomac, Maryland); Anna Pasetto (Asker, Norway); Rami Yoseph (Gaithersburg, Maryland); Winifred M. Lo (Norfolk, Virginia); Yong-Chen Lu (Little Rock, Arkansas); Maria R. Parkhurst (Ellicott City, Maryland); Paul F. Robbins (Chevy Chase, Maryland); Parisa Malekzadeh (Norfolk, Virginia) |
| ABSTRACT | Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated human p53. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Wednesday, February 21, 2024 |
| APPL NO | 18/583139 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270822 | Wilcox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PLATELET TARGETED THERAPEUTICS, LLC (Brookfield, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David A. Wilcox (Brookfield, Wisconsin); Sandra L. Haberichter (Greenfield, Wisconsin) |
| ABSTRACT | The present disclosure relates to compositions and methods for targeting expression of exogenous genes to platelets. In particular, the present disclosure relates to treatment of hemophilia and other diseases and conditions by targeting expression of exogenous agents (e.g.. clotting factors) to platelets. |
| FILED | Monday, August 07, 2023 |
| APPL NO | 18/366237 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 48/0058 (20130101) A61K 2035/124 (20130101) Peptides C07K 14/755 (20130101) Original (OR) Class C07K 14/7055 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270851 | Ho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Mitchell Ho (Urbana, Maryland); Glenn Merlino (Vienna, Virginia); Dan Li (Rockville, Maryland); Hejiao English (Columbia, Maryland); Chi-Ping Day (Rockville, Maryland) |
| ABSTRACT | Single-domain shark variable new antigen receptor (VNAR) monoclonal antibodies that specifically bind programmed death-ligand 1 (PD-L1) are described. The PD-L1-specific VNAR antibodies are capable of binding PD-L1-expressing tumor cells from human, mouse and canine origin. Immune cells expressing chimeric antigen receptors (CARs) developed using the VNAR antibodies can be used to kill PD-L1-positive tumor cells, for example in animal models of liver cancer and breast cancer. |
| FILED | Monday, June 06, 2022 |
| APPL NO | 18/567990 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4631 (20230501) A61K 39/464402 (20230501) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2827 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/52 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270854 | Chan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles K.F. Chan (Redwood City, California); Liming Zhao (Redwood City, California); Sicong Wang (Stanford, California); Michael T. Longaker (Redwood City, California); Eri Takematsu (Redwood City, California) |
| ABSTRACT | A BMP2 surrogate protein is provided comprising two different antigen binding regions (ABR), which can be configured as immunoglobulin “single variable domains” (ISV). A first ISV specifically binds to a first BMP2 receptor, e.g. BMPR1a; and a second ISV specifically binds to a second BMP2 receptor, e.g. BMPR2. In some embodiments the first and second ISV are joined by a cleavable linker that is susceptible to proteases selectively expressed in monocytic cells or macrophages, relative to skeletal stem cells. |
| FILED | Tuesday, May 24, 2022 |
| APPL NO | 18/565026 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) Peptides C07K 16/22 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2317/569 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270942 | HE |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mei HE (Gainesville, Florida) |
| ABSTRACT | Described herein are biocompatible nanocomposite hydrogel compositions for three-dimensional printing, comprising: collagen, starch, and gelatin nanoparticles. Additionally described are methods of using three-dimensional objects printed from the a nanocomposite hydrogel compositions for healing wounds and regenerating tissue. |
| FILED | Friday, June 17, 2022 |
| APPL NO | 18/568137 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/008 (20130101) A61L 26/0023 (20130101) A61L 26/0033 (20130101) A61L 26/0038 (20130101) A61L 2400/12 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Compositions of Macromolecular Compounds C08L 3/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271087 | Thomson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James A. Thomson (Madison, Wisconsin); Junying Yu (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to methods for reprogramming a somatic call to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method. |
| FILED | Thursday, January 04, 2024 |
| APPL NO | 18/404213 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0607 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2501/60 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2502/99 (20130101) C12N 2510/00 (20130101) C12N 2799/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271089 | Bharti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | THE U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Kapil Bharti (Potomac, Maryland); Davide Ortolan (Bethesda, Maryland); Ruchi Sharma (Bethesda, Maryland) |
| ABSTRACT | Methods are disclosed for producing macular, central or peripheral human retinal pigment epithelial (RPE) cells. These methods include: a) culturing stem cells, such as induced pluripotent stem cells (iPSCs), in a retinal induction medium to initiate differentiation of the cells into RPE progenitor cells; b) culturing the RPE progenitor cells in a retinal differentiation medium to further differentiate the RPE progenitor cells into committed RPE cells; c) culturing the committed RPE cells in a retinal medium to form immature RPE cells; and d) culturing the immature RPE cells in a RPE maturation medium including a retinoic acid receptor (RAR) antagonist and/or a canonical Wnt inhibitor, thereby producing macular, central or peripheral human RPE cells. |
| FILED | Thursday, May 26, 2022 |
| APPL NO | 18/562806 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) Original (OR) Class C12N 2501/02 (20130101) C12N 2501/15 (20130101) C12N 2501/105 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2506/45 (20130101) C12N 2533/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271090 | RUELLA et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Marco RUELLA (Ardmore, Pennsylvania); Sangya AGARWAL (Philadelphia, Pennsylvania); Seokjae Albert HONG (Waxhaw, North Carolina) |
| ABSTRACT | The present invention includes compositions and methods comprising CART cells with SHP-1 and/or SHP-2 genes knocked out. |
| FILED | Friday, September 01, 2023 |
| APPL NO | 18/459533 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70575 (20130101) C07K 16/2803 (20130101) C07K 2319/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 9/16 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2510/00 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 301/03048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271091 | TSOURKAS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (PHILADELPHIA, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (PHILADELPHIA, Pennsylvania) |
| INVENTOR(S) | Andrew TSOURKAS (Bryn Mawr, Pennsylvania); James Z. HUI (Philadelphia, Pennsylvania); Burcin ALTUN (Philadelphia, Pennsylvania); Fabiana ZAPPALA (Philadelphia, Pennsylvania) |
| ABSTRACT | A bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody comprising a cytotoxic lymphocyte or macrophage targeting domain and an autoantibody. Methods for producing bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody comprising a cytotoxic lymphocyte or macrophage targeting domain and an autoantibody. Methods for treating a subject in need thereof comprising administering to the subject an isolated bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody. |
| FILED | Wednesday, January 24, 2024 |
| APPL NO | 18/421975 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2809 (20130101) C07K 16/2827 (20130101) C07K 16/3015 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) Original (OR) Class C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271092 | Waller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edmund Waller (Atlanta, Georgia); Anna Morris (Atlanta, Georgia); Christopher Petersen (Atlanta, Georgia); Jian-Ming Li (Atlanta, Georgia); Reema Panjwani (Bayside, New York); Jingxia Li (Decatur, Georgia) |
| ABSTRACT | This disclosure relates to compositions and methods of reversing senescence in T cells by interrupting vasoactive intestinal peptide (VIP) signalling and/or inhibiting phosphatidylinositol-3-kinase (PI3 kinase) inhibitor signalling and uses in managing cancer and chronic viral infections. In certain embodiments, the disclosure contemplates methods of reversing T cell senescence by mixing T cell in vitro with an agent that prevents VIP from interacting with VIP receptors and/or a PI3 Kinase inhibitor. In certain embodiments, the disclosure contemplates the expansion of senescent T cells by mixing with a PI3 kinase inhibitor, an agent that block VIP and VIP receptor signalling, a VIP degrading enzyme, and combinations thereof. |
| FILED | Wednesday, November 15, 2023 |
| APPL NO | 18/510060 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/28 (20130101) A61K 38/22 (20130101) A61K 38/54 (20130101) A61K 38/208 (20130101) A61K 38/482 (20130101) A61K 38/4886 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) A61P 35/00 (20180101) Peptides C07K 16/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) Original (OR) Class C12N 2501/05 (20130101) C12N 2501/51 (20130101) C12N 2501/515 (20130101) Enzymes C12Y 304/21039 (20130101) C12Y 304/24011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271096 | Kamp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Kamp (Madison, Wisconsin); Yukihiro Saito (Okayama, Japan) |
| ABSTRACT | The present disclosure provides a method of generating right ventricle (RV) cardiomyocytes from pluripotent stem cells, populations of second heart field (SHF) cardiac progenitor cells and right ventricle (RV) cardiomyocytes produced by the method, a method of using these cells to study RV dysfunction related diseases, and a method of treating a subject with cardiac disease comprising administering to the patient the SHF cardiac progenitor cells or the RV cardiomyocytes. |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/440260 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class C12N 2501/33 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2503/00 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271097 | COLAS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandre COLAS (La Jolla, California); Maria Azzurra MISSINATO (San Diego, California); Michael S. YU (Cambridge, Massachusetts) |
| ABSTRACT | This present disclosure provides methods and pharmaceutical compositions for cell reprogramming and a pharmaceutical composition comprising the reprogrammed cells. In certain embodiments, the method of reprogramming a cell comprises reducing the expression of at least one barrier gene selected from the group consisting of ATF7IP, JUNB, ZNF207, Sp7, FOXA1, HEXIM2, SMARCA5, SOX15, CHST2 or NCEH1, or if the barrier gene is ATF7IP or SOX15, then the expression of a second barrier gene is also reduced. In another embodiment, the reprogramming method comprises reducing the expression of at least two barrier genes selected from the group consisting of ATF7IP, JUNB, ZNF207 and Sp7. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 18/568172 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) A61K 35/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 5/0657 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2501/999 (20130101) C12N 2506/28 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271098 | WOODS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OSSIUM HEALTH, INC. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erik J. WOODS (Carmel, Indiana); Brian H. JOHNSTONE (Fishers, Indiana); Dongsheng GU (Indianapolis, Indiana); Aubrey Marie SHERRY (Carmel, Indiana); Kelsey Gwen MUSALL (Avon, Indiana); John R. WOODS (Avon, Indiana); James HARDIN (Columbia, South Carolina); Alan HOOKS (Commerce City, Colorado) |
| ABSTRACT | Methods are provided for extracting bone marrow cells from bone obtained from deceased donors, for preparing the bone marrow for cryopreservation and for obtaining desired cells from cryopreserved and fresh bone marrow. |
| FILED | Friday, January 12, 2024 |
| APPL NO | 18/412312 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Diagnosis; Surgery; Identification A61B 17/1611 (20130101) A61B 2017/00831 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271103 | LI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ping LI (Carmel, Indiana); Burcin EKSER (Indianapolis, Indiana) |
| ABSTRACT | Disclosed are genetically modified porcine cells, tissues, organoids, and animals and methods of using the same for transplantation, and testing for xenoreactivity. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 18/568607 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) Original (OR) Class C12N 2502/1164 (20130101) C12N 2503/00 (20130101) C12N 2510/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271112 | Wolfe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scot Andrew Wolfe (Winchester, Massachusetts); Ester Mintzer (Cherry Valley, Massachusetts); Jeremy Luban (Shrewsbury, Massachusetts); Jason Shohet (Shrewsbury, Massachusetts) |
| ABSTRACT | The present invention utilizes a Cas9 nickase which nicks a flanking target sequence to a duplicated gene sequence (e.g., a retroviral LTR). This nicking causes a genomic collapse of the sequence between the nick and the LTR, thereby deleting the sequence from the genome. Because the nickase does not introduce mutations at the target site, this method can be repeated maximize the efficiency (e.g., 100% of retroviral genome excision. For example, this method is useful to delete all PERVs within a pig genome intended for human transplantation. Further, such PERV-free cells can then be used to clone PERV-free pigs. Furthermore, this method is useful to remove amplified gene repeats in cancer cells. |
| FILED | Tuesday, May 31, 2022 |
| APPL NO | 18/566367 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271115 | Fu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Haiyan Fu (Durham, North Carolina); Tierra Bobo (Mebane, North Carolina); Preston Samowitz (Chapel Hill, North Carolina); Brian Kuhlman (Chapel Hill, North Carolina); David Forrest Thieker (Durham, North Carolina) |
| ABSTRACT | This invention relates to methods and compositions for inhibiting or depleting antibodies, e.g., total IgG including neutralizing antibodies. In particular, the invention relates to methods of inhibiting or depleting antibodies against a heterologous agent when the heterologous agent is administered to a subject, comprising administering to the subject an effective amount of recombinant or modified Streptococcus pyogenes IgG degrading enzyme (IdeS) prepared from codon-optimized nucleic acids and/or modified nucleic acids, thereby inhibiting or depleting antibodies and inhibiting neutralization of the heterologous agent, e.g., to improve viral vector-mediated gene therapy. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 18/570529 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/4873 (20130101) A61K 48/0083 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class Enzymes C12Y 304/2201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271119 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Tina Wang (Cambridge, Massachusetts); Mary S. Morrison (Cambridge, Massachusetts) |
| ABSTRACT | Aspects of the disclosure relate to compositions, systems, and methods for evolving nucleic acids and proteins utilizing continuous directed evolution in the periplasm of a host cell. In some embodiments, the methods comprise passing a nucleic acid from cell-to-cell in a desired, function dependent manner. The linkage of the desired function and passage of the nucleic acid from cell-to-cell allows for continuous selection and mutation of the nucleic acid. |
| FILED | Wednesday, July 27, 2022 |
| APPL NO | 18/292421 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/58 (20130101) C12M 29/18 (20130101) C12M 41/36 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) C12N 7/00 (20130101) C12N 15/70 (20130101) C12N 15/1024 (20130101) Original (OR) Class C12N 15/1058 (20130101) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/19 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271124 | Ortlund et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Ortlund (Decatur, Georgia); Filipp Frank (Decatur, Georgia); William Hudson (Spring, Texas) |
| ABSTRACT | This disclosure relates to libraries of recombinant protein variants expressed on the surface of cells from expression constructs and uses in methods analyzing the impact of one or more mutations on affinity binding to specific binding agents. In certain embodiments, this disclosure relates to methods of contacting binding agents used in diagnostic test with libraries of cell surface expressed protein variants to analyze binding affinity. In certain embodiments, the protein variants are expressed on the exterior of cells containing intracellular nucleic acids with barcodes that correlate to specific amino acid variants sequences. |
| FILED | Monday, February 12, 2024 |
| APPL NO | 18/439733 |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 2770/20022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271130 | Duvall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig L. Duvall (Nashville, Tennessee); Juan M. Colazo (Nashville, Tennessee) |
| ABSTRACT | Disclosed herein are methods of treating inflammatory diseases, such as arthritis or traumatic injury, using lipophilic siRNA conjugates that can bind to albumin. An example method includes administering to a subject an effective amount of a conjugate, optionally in combination with a pharmaceutically acceptable excipient, wherein the conjugate includes a siRNA capable of inhibiting expression of a protein associated with the inflammatory disease; a lipophilic ligand capable of binding albumin; and a linker attaching the siRNA to the lipophilic ligand, the linker including a branching molecule attached to the siRNA, and a hydrophilic spacer attaching the branching molecule to the lipophilic ligand. |
| FILED | Wednesday, March 01, 2023 |
| APPL NO | 18/177068 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/315 (20130101) C12N 2310/3515 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271132 | Cai |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hua Cai (Los Angeles, California) |
| ABSTRACT | The present disclosure relates to pharmaceutical compositions comprising a miRNA inhibitor, as well as the method for using such pharmaceutical compositions. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 18/289418 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/44 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/3231 (20130101) C12N 2310/3233 (20130101) C12N 2310/3515 (20130101) Enzymes C12Y 114/13039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271138 | Hacohen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Nir Hacohen (Cambridge, Massachusetts); Matteo Gentile (Cambridge, Massachusetts); Bingxu Liu (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are compositions and methods for enhancing the activity of Stimulator of Interferon Genes (STING) with one or more agents for inhibiting the activity of one or more negative regulators of STING, including DNAJC13 and ESCRT. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 18/568797 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) Peptides C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271142 | ARORA |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rishi ARORA (Evanston, Illinois) |
| ABSTRACT | Provided herein are compositions and methods for the inhibition of nerve growth factor (NGF) and the treatment/prevention of atrial fibrillation. In particular, inhibitors of NGF expression are administered to the myocardial tissue of a subject to treat or prevent atrial fibrillation and/or autonomic nerve sprouting in the atria. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 18/570532 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/367 (20210101) A61B 5/4848 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271158 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel G. Anderson (Framingham, Massachusetts); Robert Alexander Wesselhoeft (Boston, Massachusetts); Piotr S. Kowalski (CORK, Ireland) |
| ABSTRACT | Circular RNA and methods and constructs for engineering circular RNA are disclosed. In some embodiments, the circular RNA includes the following elements arranged in the following sequence: a) an adjacent exon sequence of a 3′ Group I self-splicing intron-exon, b) an internal ribosome entry site (IRES), c) a protein coding region or noncoding region, and d) an adjacent exon sequence of a 5′ Group I self-splicing intron-exon. |
| FILED | Friday, March 15, 2024 |
| APPL NO | 18/607256 |
| CURRENT CPC | Peptides C07K 16/2803 (20130101) C07K 2317/31 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2015/859 (20130101) C12N 2015/8518 (20130101) C12N 2800/70 (20130101) C12N 2800/107 (20130101) C12N 2800/202 (20130101) C12N 2840/55 (20130101) C12N 2840/60 (20130101) C12N 2840/203 (20130101) C12N 2999/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271193 | Zhuang et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaowei Zhuang (Cambridge, Massachusetts); Jeffrey R. Moffitt (Cambridge, Massachusetts); Guiping Wang (Cambridge, Massachusetts) |
| ABSTRACT | The present invention generally relates to microscopy, and to systems and methods for imaging or determining nucleic acids or other desired targets, for instance, within cells. In certain aspects, a sample is contained within an expandable material, which is expanded and imaged in some fashion. Expansion of the material improves the effective resolution of the subsequent image. This may be combined, for example, with other super-resolution techniques, such as STORM, and/or with techniques such as MERFISH for determining nucleic acids such as mRNA within the sample, for example, by binding nucleic acid probes to the sample. Other aspects are generally directed to compositions or devices for use in such methods, kits for use in such methods, or the like. |
| FILED | Thursday, January 11, 2024 |
| APPL NO | 18/410439 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271202 | Evrony |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gilad Evrony (New York, New York) |
| ABSTRACT | Provided are compositions and methods for improved accuracy during DNA sequencing. The method can be performed without amplification prior to sequencing. The compositions and methods are used for determining single and double stranded sequences, and for accurately determining mosaic double strand mutations and single strand nucleotide changes. |
| FILED | Wednesday, January 31, 2024 |
| APPL NO | 18/428519 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/25 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/9015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271212 | OBER et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Israel) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Carole OBER (Chicago, Illinois); Selene CLAY (Chicago, Illinois); Nathan SCHOETTLER (Chicago, Illinois) |
| ABSTRACT | Provided herein are compositions and methods for the characterization and treatment of asthma. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 18/565970 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271215 | Schwartz et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David A. Schwartz (Denver, Colorado); Tasha E. Fingerlin (Aurora, Colorado); Weiming Zhang (Aurora, Colorado) |
| ABSTRACT | Disclosed are biomarkers, methods and assay systems for the identification of poor prognosis of interstitial pneumonia (pulmonary fibrosis) in an individual diagnosed with suspected of having interstitial pneumonia. |
| FILED | Wednesday, April 10, 2024 |
| APPL NO | 18/631414 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/12 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271226 | WANG et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Tza-Huei Jeff WANG (Germantown, Maryland); Aniruddha Mrithinjay KAUSHIK (Cincinnati, Ohio); Kuangwen HSIEH (Baltimore, Maryland) |
| ABSTRACT | Provided herein are methods of identifying and determining the antimicrobial susceptibility of bacteria in samples. Related devices, systems, reaction mixtures, kits, and other methods are also provided. |
| FILED | Wednesday, September 29, 2021 |
| APPL NO | 18/245048 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) B01L 2200/16 (20130101) B01L 2200/0673 (20130101) B01L 2300/0663 (20130101) B01L 2300/0829 (20130101) B01L 2300/0883 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6818 (20130101) C12Q 1/6897 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271866 | Dummer |
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| FUNDED BY |
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| APPLICANT(S) | Polarean, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew K. Dummer (Chapel Hill, North Carolina) |
| ABSTRACT | Cryo-collection systems are provided with an integrated cooler and heater thermally coupled to an accumulator. The cooler and the heater are electronically, automatically controlled to provide the cooling and then the heating to respectively collect/freeze, then thaw a collected gas, such as 129Xe, in the accumulator. |
| FILED | Tuesday, February 06, 2024 |
| APPL NO | 18/433767 |
| CURRENT CPC | Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 3/0276 (20130101) F25J 3/0685 (20130101) Original (OR) Class F25J 2205/20 (20130101) F25J 2215/36 (20130101) F25J 2270/904 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271867 | Dummer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Polarean, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew K. Dummer (Chapel Hill, North Carolina); Matthew Linford (Chapel Hill, North Carolina) |
| ABSTRACT | Cryo-collection systems are provided with a fluid flow paths to a chamber enclosing at least part of an accumulator to serially provide coolant liquid and heated liquid to provide the cooling and then the heating to respectively collect/freeze, then thaw a target gas, such as collected 129Xe, in the accumulator. |
| FILED | Tuesday, February 06, 2024 |
| APPL NO | 18/433770 |
| CURRENT CPC | Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 3/0685 (20130101) Original (OR) Class F25J 2210/42 (20130101) F25J 2215/36 (20130101) F25J 2280/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271938 | Ren et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peng Ren (Santa Cruz, California); Fatemeh Elyasi (Santa Cruz, California); Roberto Manduchi (Santa Cruz, California) |
| ABSTRACT | A computer implemented system useful for determining turns in a user's trajectory, including one or more processors; one or more memories; and one or more programs stored in the one or more memories, wherein the one or more programs executed by the one or more processors (1) receive input data, comprising orientation data and acceleration from one or more sensors carried by a user taking steps along a trajectory; (2) analyze the input data using a first trained machine learning algorithm so as to detect a plurality of n straight sections when the user is walking along an approximately straight path; (3) comprise an orientation tracker tracking an orientation of the user in each of the n straight sections, wherein the orientation comprises an estimated orientation taking into account drift of the input data outputted from the one or more sensors; and (4) comprise a turn detector detecting each of the turns, wherein each of the turns is a change in the estimated orientation of the user in the nth straight section as compared to the estimated orientation in the (n−1)th straight section. |
| FILED | Monday, June 13, 2022 |
| APPL NO | 18/567490 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/16 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/044 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272073 | ZHANG |
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| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Jitao ZHANG (Troy, Michigan) |
| ABSTRACT | A multimodal optical technique that can measure the mechanical, optical, and acoustical properties of the sample at microscopic resolution, which is based on the integration of a Brillouin microscope and a photoacoustic (PA) microscopy is provided. The multimodal technique not only can acquire co-registered Brillouin and PA signals of the sample but also allows us to utilize the sound speed measurements by PA to quantify the sample's refractive index, which is an essential property of the material and cannot be measured by either technique individually. We demonstrated the colocalization of Brillouin and time-resolved PA signals by measuring the interface of kerosene and 1% CuSO4 aqueous solution. In addition, we measured the refractive index of saline solutions with a precision of 0.003 and validated the result against published data. This multimodal modality could open new way for charactering biological cell and tissue in physiological and pathological conditions. |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/440471 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 21/636 (20130101) Original (OR) Class G01N 29/02 (20130101) G01N 29/2425 (20130101) G01N 2021/638 (20130101) G01N 2291/02466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272082 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Shaopeng Wang (Chandler, Arizona); Runli Liang (Mesa, Arizona) |
| ABSTRACT | Provided herein are systems for the label-free detection of target molecules in samples. The systems include a sensor probe positioned in a sensing region and configured to bind to receptors for the target molecules. The systems also include electrodes configured to expose the sensor probe to an alternating electric field, and a light source optically coupled to the sensor probe and configured to provide light along a length of the sensor probe. In addition, the systems also include a position sensitive photodetector configured to detect a position of light exiting the sensor probe, and a processor configured to assess, based at least in part on the position of the light exiting the sensor probe, an amplitude of oscillation of the sensor at a frequency of the alternating electric field and a direction of a displacement of the sensor. Additional systems and related methods are also provided. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 18/689180 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/7703 (20130101) Original (OR) Class G01N 27/305 (20130101) G01N 33/5438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272140 | Koo |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sophia Koo (Brookline, Massachusetts) |
| ABSTRACT | Methods for diagnosing, treating, and monitoring the treatment of fusariosis or scedosporiosis are described. The methods can include detecting the presence of one or more volatile organic compounds (VOCs) in the breath of subjects suspected of having fusariosis or scedosporiosis. |
| FILED | Monday, April 08, 2024 |
| APPL NO | 18/629273 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/497 (20130101) Original (OR) Class G01N 33/4977 (20240501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272156 | Sackstein |
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| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Sackstein (Pinecrest, Florida) |
| ABSTRACT | The present disclosure provides, inter alia, methods for selecting hematopoietic stem/progenitor cells (HSPCs) from a heterogenous population of nucleated cells, and compositions comprising selected cells useful for treatment of a medical condition. In some embodiments, the cells are selected for the characteristic markers sialylated Lewis X (sLeX), CD34+, and CD38−. In some embodiments, the selected cells comprise hematopoietic stem cells (HSCs). |
| FILED | Thursday, February 29, 2024 |
| APPL NO | 18/591921 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0662 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) C12Q 1/6881 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272161 | Taube et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Janis M. Taube (Baltimore, Maryland); Sandor Szalay (Baltimore, Maryland); Andrew M. Pardoll (Baltimore, Maryland); Elizabeth L. Engle (Baltimore, Maryland); Sneha Berry (Baltimore, Maryland); Benjamin Green (Baltimore, Maryland) |
| ABSTRACT | Provided herein are method of predicting a subject's response to immunotherapy that include (a) staining a biological sample disposed on a substrate: (b) imaging the biological sample, wherein one or more image(s) of a high-power field (HPF) is generated: (c) detecting multiple biomarkers in the biological sample; and (d) analyzing the one or more image(s), thereby predicting the subject's response to immunotherapy. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 18/568444 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/5743 (20130101) G01N 33/6854 (20130101) G01N 33/57423 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 2333/70517 (20130101) G01N 2333/70596 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272181 | Dennis et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Virginia Commonwealth University (Richmond, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Edward A. Dennis (La Jolla, California); Oswald Quehenberger (San Diego, California); Rohit Loomba (San Diego, California); Arun J. Sanyal (Richmond, Virginia) |
| ABSTRACT | The disclosure provides methods for identifying non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in a subject. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/279433 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/72 (20130101) G01N 33/92 (20130101) Original (OR) Class G01N 2570/00 (20130101) G01N 2800/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272191 | Verma et al. |
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| FUNDED BY |
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| APPLICANT(S) | DH Technologies Development Pte. Ltd. (Singapore, Singapore); United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | DH Technologies Development Pte. Ltd. (Singapore, Singapore); United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Meghav Verma (Germantown, Maryland); Samuel Michael (Germantown, Maryland); John Janiszewski (Westerly, Rhode Island); Chang Liu (Richmond Hill, Canada); Thomas R. Covey (Newmarket, Canada) |
| ABSTRACT | A method of processing a sample plate containing a plurality of samples includes aspirating simultaneously, from the sample plate, a first sample droplet from a first sample of the plurality of samples with a first pipette and a second sample droplet from a second sample of the plurality of samples with a second pipette. The sample plate also includes dispensing sequentially, from the first pipette and the second pipette, the first sample drop and the second sample drop into an open port interface (OPI). |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/439795 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/1011 (20130101) G01N 35/1072 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272253 | HAM et al. |
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| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Donhee HAM (Cambridge, Massachusetts); Bruce ROSEN (Boston, Massachusetts); Yi-Qiao SONG (Boston, Massachusetts) |
| ABSTRACT | A magnetic field monitoring system can include a host system that generates a magnetic field. The magnetic field monitoring system can include a plurality of sensor assemblies disposed apart from each other within the host system. Each of the plurality of sensor assemblies can include a coil wound around a sample and an integrated circuit coupled with the coil. The integrated circuit can perform one or more MR measurements of the sample using one or more pulse sequences. |
| FILED | Thursday, August 04, 2022 |
| APPL NO | 18/681031 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/58 (20130101) G01R 33/243 (20130101) G01R 33/302 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272258 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhixing Wang (Charlottesville, Virginia); Rajiv Ramasawmy (Bethesda, Maryland); Ahsan Javed (Vienna, Virginia); John P. Mugler, III (Charlottesville, Virginia); Craig H. Meyer (Charlottesville, Virginia); Adrienne E. Campbell (Washington, District of Columbia) |
| ABSTRACT | Acquiring 3D MRI data using spiral-in-out encoding trajectories includes calculating a variable flip angle RF series for use as refocusing pulses, wherein the RF series includes a plurality of refocusing RF pulses. A spoiler gradient waveform is applied along the spoiler gradient direction, wherein the computer alternately adds and subtracts partition encoding waveforms to the spoiler gradient waveform. The method reads MRI data from each encoding step during an MRI sequence. The MRI sequence inserts a spiral-in gradient before a first refocusing RF pulse from the RF sequence, overlaps a pre-winder lobe for the encoding trajectory with the spoiler gradient waveform having the partition encoding waveforms added therein, and overlaps a rewinder lobe for the encoding trajectory with the spoiler gradient waveform having the partition encoding waveforms subtracted there from. |
| FILED | Tuesday, January 02, 2024 |
| APPL NO | 18/402593 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/586 (20130101) G01R 33/5615 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272426 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Weijian Yang (Redwood City, California); Junjie Hu (Davis, California) |
| ABSTRACT | A metalens array for three-dimensional (3D) imaging is disclosed. This metalens array includes an array of metalens units. Each metalens unit in the array is configured with an extended depth of view (DOV) for projecting a cluster of object sources positioned in a range of object distances in the axial direction into a cluster of image spots in an image plane such that each of the image spots remains in focus and is separated from other image spots in the cluster of image spots. Moreover, the metalens array is configured to project the cluster of object sources into multiple clusters of image spots in the image plane, wherein each cluster of image spots is a different copy of the cluster of object sources in the image plane located apart from other clusters of image spots. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 18/569400 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/001 (20130101) G02B 27/0075 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272449 | Xu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Fan Xu (West Lafayette, Indiana); Fang Huang (West Lafayette, Indiana); Donghan Ma (West Lafayette, Indiana) |
| ABSTRACT | A method of in situ point spread function (PSF) retrieval is disclosed which includes encoding 3D location of molecules into PSFs, receiving molecule-generated images containing PSFs, segmenting the images into sub-PSF, initializing template PSFs from a pupil function, determining a statistical measure of a predetermined function between the sub- and template PSFs, associating each of the sub-PSFs with a template PSF, aligning and averaging the sub-PSF, applying a phase retrieval algorithm to the averaged sub-PSFs to update the pupil function, regenerating the template PSFs, repeating until a difference between a new and a prior generation pupil function is below a predetermined threshold, generating in situ PSFs from the last pupil function, and applying a maximum likelihood estimation algorithm based on the in situ PSFs and the sub-PSF to thereby generate lateral and axial locations of molecules. |
| FILED | Monday, April 15, 2024 |
| APPL NO | 18/636195 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/367 (20130101) G02B 26/0825 (20130101) G02B 27/58 (20130101) Original (OR) Class G02B 27/0068 (20130101) Image Data Processing or Generation, in General G06T 2207/10056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273677 | KIM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Young L. KIM (West Lafayette, Indiana); Yuhyun JI (West Lafayette, Indiana); Sang Mok PARK (West Lafayette, Indiana); Semin KWEON (West Lafayette, Indiana); Jungwoo LEEM (West Lafayette, Indiana) |
| ABSTRACT | A method of generating an image or video of a field of interest of a sample which includes obtaining i) a first RGB image from a field of interest of a sample, and ii) hyperspectral data from a subarea of the field of interest, extracting an RGB image of the subarea from the first RGB image of the field of interest, applying the hyperspectral data of the subarea to conduct a spectroscopic analysis of a sample thereby generating spectral parameters, inputting i) the spectral parameters, and ii) the first RGB image, collectively as training input data to a deep learning model (DLM), training the DLM with the training input data thus generating a trained DLM, obtaining and inputting a second RGB image of about the field of interest to the trained DLM, and outputting from the trained DLM a spectral map for the field of interest. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/423669 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) G01N 33/4833 (20130101) Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 7/0012 (20130101) G06T 2207/10016 (20130101) G06T 2207/10024 (20130101) G06T 2207/10056 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) Pictorial Communication, e.g Television H04N 23/10 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273678 | VALM et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alex M. VALM (Albany, New York); Yunlong FENG (Slingerlands, New York) |
| ABSTRACT | There is set forth herein, according to one embodiment, receiving a real image representing a target in which endmembers are present in unknown proportions; and searching and optimizing an abundance matrix space expressed in an unmixing formula that references together with the abundance matrix space, image information of the real image and an endmember spectral profile matrix that specifies spectral profiles for a set of differentiated reference endmembers; wherein as a result of the searching and optimizing the abundance matrix space, there is identified a set of unmixed real image endmembers and abundances associated to the unmixed real image endmembers. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/427449 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273723 | Tison et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Geoffrey H. Tison (Oakland, California); Robert Avram (Mont-Royal, Canada); Jeffrey E. Olgin (Oakland, California) |
| ABSTRACT | Disclosed herein are methods and systems for angiography interpretation. In one particular embodiment a method includes: classifying the primary anatomic structure of one or more angiogram images of a first patient; classifying the projection angle of the one or more angiogram images of the first patient; labeling stenoses within the one or more angiogram images of the first patient classified as including a left or right coronary artery; producing one or more angiogram images of a second patient with corresponding estimated stenoses of the second patient to produce training data; training a machine learning model with the training data; estimating the arterial stenoses severity of the first patient by running the machine learning model on the filtered and labeled one or more angiogram images of the first patient, wherein the machine learning model is only run on angiogram images previously labeled as including stenoses. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 18/568693 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0014 (20130101) Original (OR) Class G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/20132 (20130101) G06T 2207/30048 (20130101) G06T 2207/30101 (20130101) G06T 2210/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273899 | Nallasamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nambi Nallasamy (Ann Arbor, Michigan); Bradford Tannen (Superior Township, Michigan); Shahzad Mian (Superior Township, Michigan) |
| ABSTRACT | Systems and methods for using machine learning to analyze a surgical video and assess performance of a surgeon conducting a surgical procedure which may include receiving surgical video data including one or more images capturing at least a portion of an ophthalmic surgical procedure from a user device. Processing the surgical video data using one or more trained assessment machine learning models to generate one or more assessment metrics, wherein the one or more trained assessment machine learning models are trained using historical ophthalmic surgery data and the one or more assessment metrics include one or more of a surgical instrument metric, a surgical phase metric, or an anterior capsulotomy metric. Generating a performance assessment of the surgeon based upon at least the one or more assessment metrics and providing the performance assessment of the surgeon to the user device. |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/440436 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06398 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10016 (20130101) G06T 2207/20081 (20130101) G06T 2207/30041 (20130101) Image or Video Recognition or Understanding G06V 10/70 (20220101) G06V 10/273 (20220101) G06V 20/41 (20220101) Original (OR) Class G06V 2201/034 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274300 | PATEK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Stephen D. PATEK (Charlottesville, Virginia); Marc D. BRETON (Charlottesville, Virginia) |
| ABSTRACT | A method and system use mathematical models and available patient information to virtualize a continuous glucose monitoring trace for a period of time. Such a method and system can generate the virtualized trace when episodic patient data is incomplete. Such a method and system can also rely on self-monitored blood glucose measurement information to improve the virtualized continuous glucose monitoring trace. |
| FILED | Tuesday, April 16, 2024 |
| APPL NO | 18/636608 |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 40/63 (20180101) G16H 50/50 (20180101) Original (OR) Class G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240276648 | Yi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ning Yi (University Park, Pennsylvania); Yuyan Gao (University Park, Pennsylvania); Antonino Lo Verso, Jr. (University Park, Pennsylvania); Jia Zhu (University Park, Pennsylvania); Daniel Erdely (University Park, Pennsylvania); Robert Lavelle (University Park, Pennsylvania); Huanyu Cheng (University Park, Pennsylvania) |
| ABSTRACT | The invention includes methods of forming electronic circuitry on a target surface using intense pulsed light-induced mass transfer (IPLMT) of metal nanoparticles (NPs) by applying a pliable mask to a target surface, coating a carrier film with metal NPs, mounting the carrier film to the target surface and over the pliable mask so that the pliable mask is sandwiched between the target surface and the metal NPs. and exposing the metal NPs to light energy to cause atoms of the metal NPs to evaporate and transport through openings of the pliable mask and condense on the target surface, producing a conductive pattern of condensed metal on the target surface. Certain implementations may utilize a kirigami-patterned pliable mask to enhance conformity to a freeform 3D target surface. In certain implementations, zinc (Zn) may be formed by IPLMT of Zn NPs to the target surface. |
| FILED | Wednesday, March 30, 2022 |
| APPL NO | 18/561934 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/28 (20210101) A61B 5/296 (20210101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) H05K 3/143 (20130101) Original (OR) Class H05K 3/146 (20130101) H05K 2203/083 (20130101) H05K 2203/0156 (20130101) H05K 2203/0557 (20130101) H05K 2203/1131 (20130101) H05K 2203/1173 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20240269635 | PARKINSON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | C-ZERO, INC. (Goleta, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brett PARKINSON (Goleta, California); Andrew CALDWELL (Goleta, California); Samuel SHANER (Goleta, California); Eric MCFARLAND (Goleta, California) |
| ABSTRACT | A reactor system for high temperature reactions of reactants includes at least one reactant containing carbon. The reactor includes a reactor, a liquid media disposed within the reactor, and a solid carbon reaction product. The liquid media does not react irreversibly with the reactant to form products, and the liquid media wets at least a portion of a surface within the reactor. The solid carbon reaction product does not contact at least the portion of the surface within the reactor where the liquid media wets the portion of the surface within the reactor. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 18/568514 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/22 (20130101) B01J 10/005 (20130101) Original (OR) Class B01J 19/0026 (20130101) B01J 19/26 (20130101) B01J 2219/0263 (20130101) B01J 2219/0272 (20130101) B01J 2219/0277 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269659 | MA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (TAMPA, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shengqian MA (Tampa, Florida); Zheng NIU (Tampa, Florida) |
| ABSTRACT | Described herein are compositions composed of frustrated Lewis pairs impregnated in porous materials such as, for example, metal-organic frameworks, and their uses thereof. These compositions may allow new applications of frustrated Lewis pairs in catalysis by sequestering and protecting the frustrated Lewis pair within the nanospace of the porous material. Also provided are methods of hydrogenating an organic compound having at least one unsaturated functional group comprising using the compositions described herein. |
| FILED | Friday, December 22, 2023 |
| APPL NO | 18/394919 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0275 (20130101) B01J 31/1691 (20130101) Original (OR) Class B01J 2231/643 (20130101) B01J 2231/645 (20130101) B01J 2531/62 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/0015 (20130101) Acyclic or Carbocyclic Compounds C07C 67/303 (20130101) C07C 209/52 (20130101) C07C 213/02 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04216 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269691 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jian Liu (Richland, Washington); B. Peter McGrail (Pasco, Washington); Satish Nune (Richland, Washington); Michael Sinnwell (Richland, Washington); Praveen Thallapally (Richland, Washington) |
| ABSTRACT | Disclosed herein are embodiments of a polymer-functionalized particle for using in isolating and extracting solutes, such as rare earth metals, lithium, and the like. The polymer-functionalized particles exhibit strong resistance to agglomeration and degradation even in high ionic strength and/or temperature environments. A post-particle synthesis method for making the polymer-functionalized particle is disclosed, along with a magnetic separation device and that can be used in system embodiments to facilitate use and regeneration of the polymer-functionalized particles in solute extraction. |
| FILED | Wednesday, February 28, 2024 |
| APPL NO | 18/590413 |
| CURRENT CPC | Separation B01D 15/203 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/01 (20130101) B03C 1/30 (20130101) Original (OR) Class B03C 1/288 (20130101) B03C 1/0335 (20130101) B03C 2201/18 (20130101) B03C 2201/20 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 28/02 (20130101) C08F 128/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0206 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/047 (20130101) H01F 1/0054 (20130101) H01F 1/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269774 | Dehoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); Eck Industries Incorporated (Manitowoc, Wisconsin); University of Tennessee Research Foundation (Knoxville, Tennessee); Lawrence Livermore National Security, LLC (Livermore, California); Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ryan R. Dehoff (Knoxville, Tennessee); Hunter B. Henderson (Livermore, California); Scott McCall (Livermore, California); Richard Michi (Knoxville, Tennessee); Peeyush Nandwana (Oak Ridge, Tennessee); Ryan Ott (Ames, Iowa); Alexander J. Plotkowski (Knoxville, Tennessee); Orlando Rios (Knoxville, Tennessee); Amit Shyam (Knoxville, Tennessee); Zachary C. Sims (Knoxville, Tennessee); Kevin D. Sisco (Knoxville, Tennessee); David Weiss (Manitowoc, Wisconsin); Ying Yang (Knoxville, Tennessee) |
| ABSTRACT | Disclosed herein are embodiments of an Al—Ce—Ni alloy for use in additive manufacturing. The disclosed alloy embodiments provide fabricated objects, such as bulk components, comprising a heterogeneous microstructure and having good mechanical properties even when exposed to conditions used during the additive manufacturing process. Methods for making and using alloy embodiments also are disclosed herein. |
| FILED | Thursday, April 11, 2024 |
| APPL NO | 18/633192 |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 2009/0824 (20130101) B22F 2301/052 (20130101) B22F 2304/10 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/342 (20151001) Original (OR) Class B23K 2103/10 (20180801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 70/10 (20200101) Alloys C22C 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270146 | Campbell et al. |
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| FUNDED BY |
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| APPLICANT(S) | Terabase Energy, Inc. (Berkeley, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew Campbell (Berkeley, California); Brian Coleman (Portland, Oregon); Tianyu Zhao (Pacifica, California); Adam Hansel (Davis, California); Soren Jensen (Corte Madera, California) |
| ABSTRACT | A solar table mobile transport is described that moves a solar table to a point of installation. The solar table mobile transport comprises multiple motors that allow movement within a three-dimensional coordinate system as well as provide angular controls of pitch, yaw and roll. These motors enable at least one alignment process used to install the solar table to a mounting structure within a solar system. |
| FILED | Monday, March 25, 2024 |
| APPL NO | 18/616152 |
| CURRENT CPC | Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects B60P 3/00 (20130101) Original (OR) Class Solar Heat Collectors; Solar Heat Systems F24S 25/30 (20180501) F24S 25/65 (20180501) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 99/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270232 | Koti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Archit N. Koti (Columbus, Indiana); Rohinish Gupta (Columbus, Indiana); Xing Jin (Columbus, Indiana); Kenneth M. Follen (Greenwood, Indiana); Arun Prakash Thunga Gopal (Columbus, Indiana); Manik Narula (Columbus, Indiana) |
| ABSTRACT | Methods and systems for improving fuel economy and reducing emissions of a vehicle with an electric motor, an engine and an energy storage device are disclosed. The methods and systems involve obtaining lookahead information and current state information, wherein the lookahead information includes a predicted vehicle speed, and the current state information includes a current state of charge (SOC) for the energy storage device coupled to the electric motor; and determining, based on the lookahead information and the current state information, a target power split between the energy storage device and the engine. |
| FILED | Wednesday, April 10, 2024 |
| APPL NO | 18/632075 |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 58/13 (20190201) B60L 2240/12 (20130101) B60L 2240/525 (20130101) B60L 2260/54 (20130101) B60L 2270/12 (20130101) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 20/16 (20160101) Original (OR) Class B60W 30/1882 (20130101) B60W 40/105 (20130101) B60W 50/0097 (20130101) B60W 2510/244 (20130101) B60W 2520/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270597 | Morgan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dane Morgan (Middleton, Wisconsin); Jun Meng (Madison, Wisconsin); Ryan Matthew Jacobs (Middleton, Wisconsin) |
| ABSTRACT | Devices are provided, which in embodiments, comprise a source configured to generate oxygen ions via a redox reaction; and an oxygen ion transport material through which oxygen ions generated from the source are transported. The oxygen ion transport material may have either: Formula I Ax+B2y+C4z+O12 2− wherein x+2y+4z=24 and (x, y, z) is (4, 2, 4), (x, y, z) is (2, 1, 5), or (x, y, z) is (3, 2.5, 4); Formula II A4x+B5y+C4z+O222− wherein 4x+5y+4z=44 and (x, y, z) is (2, 4, 4) or (x, y, z) is (3, 3.2, 4) or (x, y, z) is (2.5, 3.6, 4); or Formula III Bi2MO4X; wherein A, B, and C are independently selected from alkali metals, alkaline earth metals, transition metals, post-transition metals, metalloids, lanthanoids, P, Th, and combinations thereof, and wherein M is selected from rare earth elements and combinations thereof and X is selected from halogens and combinations thereof. Methods of using the devices are also provided, which in embodiments, which comprise transporting oxygen ions generated from the source through the oxygen ion transport material. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 18/565772 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 13/0203 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270612 | Stetson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Caleb C. Stetson (Idaho Falls, Idaho); Hyeonseok Lee (Ammon, Idaho); Christopher J. Orme (Firth, Idaho); Daniel M. Ginosar (Idaho Falls, Idaho); Aaron D. Wilson (Idaho Falls, Idaho) |
| ABSTRACT | A method of removing one or more of solutes from an aqueous solution comprises introducing, into a first fractional crystallization chamber, dimethyl ether and a salt containing solution comprising one or more dissolved salts to form an aqueous solution, and precipitating a first solid from the aqueous solution. Related systems and additional methods are also described. |
| FILED | Tuesday, June 07, 2022 |
| APPL NO | 18/567344 |
| CURRENT CPC | Separation B01D 9/004 (20130101) B01D 9/0036 (20130101) B01D 9/0059 (20130101) B01D 2009/0086 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/54 (20130101) Original (OR) Class C02F 2001/5218 (20130101) C02F 2101/10 (20130101) C02F 2103/16 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/02 (20130101) C22B 7/006 (20130101) C22B 23/0461 (20130101) C22B 26/20 (20130101) C22B 59/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270880 | McLoughlin et al. |
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| FUNDED BY |
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| APPLICANT(S) | BRASKEM AMERICA, INC. (Philadelphia, Pennsylvania); Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kimberly Miller McLoughlin (Pittsburgh, Pennsylvania); Sarah Mitchell (Pittsburgh, Pennsylvania); Michelle Sing (Pittsburgh, Pennsylvania); Jayme Kennedy (Pittsburgh, Pennsylvania); Ica Manas-Zloczower (Cleveland, Ohio); Alireza Bandegi (Cleveland, Ohio); Amin Osouski (Cleveland, Ohio); Thomas Gray (Cleveland, Ohio) |
| ABSTRACT | This invention relates to a process for producing a recyclable ethylene-vinyl ester polymer comprising reacting an ethylene-vinyl ester polymer having an irreversibly crosslinked structure with a poly(vinyl alcohol) (PVA), via a transesterification reaction, in the presence of a transesterification catalyst, to produce a recyclable ethylene-vinyl ester vitrimer. This invention also relates to a recyclable ethylene-vinyl ester vitrimer prepared according to the process. |
| FILED | Friday, December 22, 2023 |
| APPL NO | 18/394838 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/04 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/14 (20130101) Original (OR) Class C08F 210/02 (20130101) C08F 218/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271118 | Knipe et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer M. Knipe (Oakland, California); Sarah Baker (Dublin, California); Joshua R. Deotte (Livermore, California); Fang Qian (Dublin, California) |
| ABSTRACT | According to one inventive concept, a method for forming a bioreactor includes: forming a three-dimensional structure using an additive manufacturing technique; infilling the at least one side of the three-dimensional structure with a mixture for forming a polymer-encapsulated whole cells; and curing the infilled three-dimensional structure. |
| FILED | Friday, March 01, 2024 |
| APPL NO | 18/593547 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Apparatus for Enzymology or Microbiology; C12M 1/002 (20130101) C12M 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) C12N 11/089 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271168 | YOSHIKUNI et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yasuo YOSHIKUNI (Orinda, California); Zong-Yen WU (Berkeley, California); Ping-Hung HSIEH (Berkeley, California); Sudharsan DWARAKNATH (Berkeley, California); Zengyi SHAO (Ames, Iowa); Wan SUN (Ames, Iowa); Joshua D. RABINOWITZ (Princeton, New Jersey); Yihui SHEN (Princeton, California) |
| ABSTRACT | The present invention provides for a genetically modified yeast host cell comprising a heterologous citramalate synthase, or multiple copies of a citramalate synthase, and knocked out or reduced in expression, or under conditional expression, for an endogenous or native pyruvate decarboxylase (PDC) gene; a method for constructing the genetically modified yeast host cell, and a method for producing citramalate using the genetically modified yeast host cell. |
| FILED | Thursday, February 15, 2024 |
| APPL NO | 18/443118 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) Original (OR) Class Enzymes C12Y 203/01182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271303 | Su et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiao Su (Champaign, Illinois); Stephen R. Cotty (Champaign, Illinois) |
| ABSTRACT | An electrochemical system for selective recovery of gold from electronic waste and mining streams includes a vessel configured for flow of fluid therethrough, a working electrode positioned in the vessel, where the working electrode comprises a redox-active metallopolymer, and a counter electrode spaced apart from the working electrode in the vessel. An electrochemical method for selective gold recovery includes selectively electrochemically adsorbing gold complexes from a leach solution onto a redox-active metallopolymer, and electrochemically releasing the gold complexes from the redox-active metallopolymer into a collection fluid. |
| FILED | Thursday, February 08, 2024 |
| APPL NO | 18/436586 |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/20 (20130101) Original (OR) Class C25C 7/02 (20130101) C25C 7/04 (20130101) C25C 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271311 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaojie Xu (Union City, California); Kyoung Eun Kweon (Pleasanton, California); Christine A. Orme (Oakland, California); Babak Sadigh (Danville, California); April Sawvel (Livermore, California) |
| ABSTRACT | A nanocrystal film product formed by one-step ligand exchange includes at least one dimension greater than 100 nm and ordered nanocrystals characterized as having a domain size of greater than 100 nm. |
| FILED | Monday, April 15, 2024 |
| APPL NO | 18/636066 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) C01P 2006/60 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/661 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 2/04 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271324 | KARUNADASA et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hemamala Indivari KARUNADASA (Palo Alto, California); Abraham SALDIVAR (Stanford, California); Michael AUBREY (Stanford, California) |
| ABSTRACT | Layered or 2D halide perovskites form in solution through the templating effects of organoammnonium groups. The use of organic groups with two different functionalities allows for the formation of a perovskite/non-perovskite heterostructure in aqueous or organic solution. A first functional group templates the perovskite and a second functional group templates a new 2D or ID inorganic non-perovskite lattice between the perovskite sheets. The perovskite and the intergrowth may be separated from each other by organic molecules, or they may be in contact with each other (e.g., by sharing an atom). |
| FILED | Wednesday, June 15, 2022 |
| APPL NO | 18/569351 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) C30B 29/54 (20130101) C30B 29/68 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) H01L 31/032 (20130101) H01L 31/0216 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271417 | Dickson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IBACOS, Inc. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bruce Dickson (West Mifflin, Pennsylvania) |
| ABSTRACT | An insulated siding sheet includes an integrated insulation material and a plank siding. The integrated insulation material includes: (i) a back side; (ii) a front side opposite the back side; (iii) a top horizontal edge having a 45 degree angle; and (iv) a bottom horizontal edge having a 45 degree angle, in which the back side of the integrated insulation material has vertical grooves that extend from the top horizontal edge to the bottom horizontal edge. The plank siding is attached to the front side of the integrated insulation material. The plank siding includes a top horizontal edge and a bottom horizontal edge that both have a portion of the plank siding cut-away to overlap with horizontal edges of adjacent insulated siding sheets. An insulated siding sheet system and a building having the insulated siding sheet system is also included. |
| FILED | Friday, December 08, 2023 |
| APPL NO | 18/534440 |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/80 (20130101) Original (OR) Class E04B 2/08 (20130101) E04B 2002/0208 (20130101) E04B 2103/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271480 | Pilon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Laurent Pilon (Sherman Oaks, California); Bruce S. Dunn (Los Angeles, California); Sarah H. Tolbert (Encino, California); Michal Marszewski (Los Angeles, California); Yan Yan (Los Angeles, California); Sophia C. King (Los Angeles, California); Esther H. Lan (Los Angeles, California); Danielle Butts (Los Angeles, California); Patricia E. McNeil (Los Angeles, California) |
| ABSTRACT | Materials and methods for preparing thick, mesoporous silica monolithic slabs and coatings with high transparency and low thermal conductivity are provided. The transparent silica materials are particularly suited for window or solar applications including insulation barriers for existing or new single, double pane windows or glass panel building components. The template-free, water-based sol-gel methods produce slabs or coatings by gelation of a colloidal suspension of silica or other oxide nanoparticles or by ambigel formation and then ageing and drying the gels under ambient conditions. Solvent exchanges with nonpolar, low-surface-tension solvents help to avoid cracking caused by drying stress. Mesoporous slabs can also be cast in molds on perfluorocarbon liquid substrates to reduce adhesion and enable gels to shrink freely during aging and drying without incurring significant stress that could cause fracture. |
| FILED | Wednesday, November 01, 2023 |
| APPL NO | 18/499451 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/1543 (20130101) C01B 33/1585 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 27/048 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 3/6612 (20130101) E06B 3/6715 (20130101) Original (OR) Class E06B 3/66342 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271548 | Terwilliger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neil J. Terwilliger (Cheshire, Connecticut); Joseph E. Turney (Amston, Connecticut) |
| ABSTRACT | A turbine engine assembly includes a core engine that generates an exhaust gas flow, a condenser where water is extracted from the exhaust gas flow, an evaporator where heat is input into the water that is extracted by the condenser to generate a first steam flow, a first steam turbine where the first steam flow is expanded and cooled to generate a first cooled flow, a bypass passage that defines a path for the first steam flow around the first steam turbine, and a superheater where at least one of the first steam flow and the first cooled flow is reheated to generate a second steam flow. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/108372 |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 13/02 (20130101) F01D 25/32 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/72 (20130101) F05D 2220/74 (20130101) F05D 2220/323 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271549 | Terwilliger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neil J. Terwilliger (Cheshire, Connecticut); Joseph B. Staubach (Colchester, Connecticut) |
| ABSTRACT | A turbine engine assembly includes a core engine that generates an exhaust gas flow, a condenser where water is extracted from the exhaust gas flow, an evaporator where heat is input into the water that is extracted by the condenser into a first steam flow, a steam turbine where the first steam flow is expanded and cooled, and a superheater where additional heat is input into the first steam flow that is exhausted from the steam turbine to generate a second steam flow. The second steam flow is injected into a core flow path of the core engine. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/108336 |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 7/223 (20130101) F01K 11/02 (20130101) Original (OR) Class F01K 15/02 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271550 | Terwilliger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RTX CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Neil J. Terwilliger (Cheshire, Connecticut); Joseph B. Staubach (Colchester, Connecticut) |
| ABSTRACT | A turbine engine assembly includes a core engine that generates an exhaust gas flow, a condenser where water is extracted from the exhaust gas flow, an evaporator where heat is input into the water that is extracted by the condenser into a first steam flow, a steam turbine where the first steam flow is expanded and cooled, and a superheater where additional heat is input into the first steam flow that is exhausted from the steam turbine to generate a second steam flow. The second steam flow is injected into a core flow path of the core engine. |
| FILED | Wednesday, April 03, 2024 |
| APPL NO | 18/625755 |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 7/223 (20130101) F01K 11/02 (20130101) Original (OR) Class F01K 15/02 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272018 | BERKLAND et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cory BERKLAND (Wildwood, Missouri); Jonathan MILLER (Lawrence, Kansas) |
| ABSTRACT | Described herein are magnetic sensors (e.g., force sensors) as well as methods of making and using thereof The magnetic sensors can employ a soft magnetic composite (e.g a composite comprising a population of magnetic particles dispersed within an elastomeric resin) paired with a magnetometer. These sensors can overcome many of the traditional shortcomings that have hampered the effectiveness of existing compression sensors in certain applications, including large size, a lack of 3-dimensional sensing capacity, need for sensors to incorporate rigid components, and/or signal quality issues associated with the orientation or deformation of soft composites under compression. |
| FILED | Tuesday, May 31, 2022 |
| APPL NO | 18/565719 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 2562/0223 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/122 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272072 | Culp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Culp (Wexford, Pennsylvania); Ki-Joong Kim (Pittsburgh, Pennsylvania); Jeffrey Wuenschell (Columbus, Ohio) |
| ABSTRACT | An optical fiber comprising a layer of coating composition disposed on the exterior of a glass fiber. The layer of coating composition comprises plasmonic nanocrystals dispersed in a porous polymer such as one or a plurality of polymers with intrinsic microporosity (PIMS). The layer of coating composition may be a composite comprising polymer and functionalized plasmonic nanocrystals. A method of making the coated optic fiber is also described. The coated optic fiber can be used to make a sensor and measure an analyte by measuring light transmission through the fiber. |
| FILED | Friday, February 09, 2024 |
| APPL NO | 18/438355 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) Original (OR) Class G01N 21/648 (20130101) G01N 21/7703 (20130101) G01N 2021/6484 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272244 | Owens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Israel Owens (Albuquerque, New Mexico); Andrew Charles Biller (Albuquerque, New Mexico) |
| ABSTRACT | A magneto-optical sensor can be used to measure electrical current with a very narrow pulse width as sensed by the magnetic field in the transmission line region of a pulsed power accelerator. Pulsed power accelerator experimental results agreed remarkably well with the Faraday effect theory, device physical model, and reference electrical current shunt data. |
| FILED | Tuesday, November 14, 2023 |
| APPL NO | 18/508794 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 15/246 (20130101) G01R 33/0322 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272253 | HAM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Donhee HAM (Cambridge, Massachusetts); Bruce ROSEN (Boston, Massachusetts); Yi-Qiao SONG (Boston, Massachusetts) |
| ABSTRACT | A magnetic field monitoring system can include a host system that generates a magnetic field. The magnetic field monitoring system can include a plurality of sensor assemblies disposed apart from each other within the host system. Each of the plurality of sensor assemblies can include a coil wound around a sample and an integrated circuit coupled with the coil. The integrated circuit can perform one or more MR measurements of the sample using one or more pulse sequences. |
| FILED | Thursday, August 04, 2022 |
| APPL NO | 18/681031 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/58 (20130101) G01R 33/243 (20130101) G01R 33/302 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272397 | OHODNICKI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania); BRAINDRIP, LLC (JACKSONVILLE, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania); BRAINDRIP, LLC (JACKSONVILLE, Florida) |
| INVENTOR(S) | PAUL R. OHODNICKI (ALLISON PARK, Pennsylvania); KENT WEISENBERG (JACKSONVILLE, Florida); IBRAHIIM SYED (JACKSONVILLE, Florida) |
| ABSTRACT | A cable installation apparatus includes a drive assembly and a cable assembly, wherein the apparatus dispenses the cable onto and/or into and along the inner surface of a tubular structure while being moved. The apparatus also includes a securing assembly for holding and dispensing a securing material component while the apparatus is being moved along the length of the tubular structure, wherein the securing material component secures the cable to the inner surface of the tubular structure after being dispensed from the apparatus. A cleaning assembly may also be included for cleaning portions of the inner surface of the tubular structure while the apparatus is being moved along the length of the tubular structure and before the cable is dispensed onto and/or into the portions of the inner surface of the tubular structure. |
| FILED | Friday, August 12, 2022 |
| APPL NO | 18/568463 |
| CURRENT CPC | Cleaning in General; Prevention of Fouling in General B08B 9/051 (20130101) Optical Elements, Systems, or Apparatus G02B 6/54 (20130101) G02B 6/502 (20130101) Original (OR) Class Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 1/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273393 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yue Wu (New Haven, Connecticut); Lin Zhong (New Haven, Connecticut); Namitha Godawatte Liyanage (New Haven, Connecticut) |
| ABSTRACT | Provided herein are methods of solving minimum-weight perfect matching (MWPM) for quantum error correction. The methods include i) partitioning an algorithm into a dual module and a primal module; ii) computing a maximum update length in the dual module; iii) gathering a return value in the dual module, the return value including a growth event or a conflict event; iv) resolving a conflict in the primal module when the return value is the conflict event; and v) setting a growth state in the dual module for each of one or more nodes when the return value is the growth event. |
| FILED | Friday, February 09, 2024 |
| APPL NO | 18/437441 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/60 (20220101) G06N 10/70 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274308 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matthew M. Jones (Idaho Falls, Idaho); Nick H. Erfurth (Idaho Falls, Idaho); Joey A. Charboneau (Blackfoot, Idaho) |
| ABSTRACT | An ablation chamber assembly, comprising a chamber, a support structure, and a liner. The chamber may have a fluid inlet, a central cavity, and a fluid outlet. The support structure may be disposed in the interior cavity and include a support flange and a fluid passageway defined through the support structure. The liner may be disposed in the chamber over the support flange of the support structure. The liner may include a central opening and one or more sample chambers spaced about the central opening. The one or more sample chambers may be configured to receive testing samples. The support structure fluid passageway may be configured to direct a fluid from the fluid inlet into one sample chamber of the one or more sample chambers through the central opening of the liner and out the fluid outlet. |
| FILED | Wednesday, January 24, 2024 |
| APPL NO | 18/421897 |
| CURRENT CPC | Nuclear Reactors G21C 17/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274309 | Stone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRIAD National Security, LLC. (Los Alamos, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Stone (Los Alamos, New Mexico); Oka Jude (Los Alamos, New Mexico) |
| ABSTRACT | A container includes a two-piece lid, a base, and an O-ring. The two-piece lid includes a plate and a connector including a first leg with internal threads and a second leg. The base defines a cavity with an open end and a closed end and includes a collar with external threads. The O-ring is configured to form a seal between the two-piece lid and the base. The internal threads on the first leg of the connector engage the external threads of the collar responsive to rotation of the two-piece lid relative to the base. The second leg of the connector drives the plate towards the base responsive to the internal threads on the first leg of the connector engaging the external threads of the collar. The O-ring forms the seal as the internal threads on the first leg of the connector engage the external threads of the collar |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/109433 |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 51/1616 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/12 (20130101) Original (OR) Class G21F 5/015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274352 | Mohammad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mostak Mohammad (Knoxville, Tennessee); Omer C. Onar (Knoxville, Tennessee); Jonathan P. Wilkins (Knoxville, Tennessee); Veda Prakash Galigekere Nagabhushana (Knoxville, Tennessee); Gui-Jia Su (Knoxville, Tennessee) |
| ABSTRACT | A receiver construction and/or a transmitter assembly is provided for transfer of wireless power. The receiver and/or transmitter assemblies may include a respective receiver or transmitter coil assembly, a backing, and a core provided between the backing and the respective receiver or transmitter coil assembly. The receiver coil assembly and/or the transmitter coil assembly may include one or more coils provided in an epoxy operable to facilitate thermal transfer from the one or more coils to at least one of the core and the backing. A thermally conductive element may be provided between the backing and the core. |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/440074 |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 53/122 (20190201) B60L 53/302 (20190201) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/10 (20130101) H01F 27/24 (20130101) H01F 38/14 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274746 | SCHULTE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin Louis SCHULTE (Denver, Colorado); Wondwosen Tilahun METAFERIA (Rio Rancho, New Mexico); Aaron Joseph PTAK (Littleton, Colorado); John David SIMON (Austin, Texas) |
| ABSTRACT | Disclosed herein are methods for the growth of (110) GaAs solar cells by hydride vapor phase epitaxy (HVPE) as an advance towards a (110)-oriented device platform with substrate reuse via spalling. Controlled spalling offers a fracture-based path to substrate amortization, allowing device removal and substrate reuse, but the faceted surface generated in spalling of (100)-GaAs presents hurdles to direct regrowth of subsequent devices. Spalling of (110)-oriented substrates takes advantage of the natural (110) cleavage plane in zinc-blende III-V materials, eliminating this faceting. |
| FILED | Monday, June 06, 2022 |
| APPL NO | 18/566764 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/18 (20130101) C30B 25/20 (20130101) C30B 29/40 (20130101) C30B 29/42 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0735 (20130101) H01L 31/1844 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274806 | Chiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Yet-Ming Chiang (Weston, Massachusetts); Richard Park (Somerville, Massachusetts); Venkatasubramanian Viswanathan (Pittsburgh, Pennsylvania); Shashank Sripad (Pittsburgh, Pennsylvania); Zijian Hong (Pittsburgh, Pennsylvania); Pinwen Guan (Pittsburgh, Pennsylvania) |
| ABSTRACT | Electrochemical devices, and associated materials and methods, are generally described. In some embodiments, an electrochemical device comprises an electroactive material. The electroactive material may comprise an alloy having a solid phase and a liquid phase that co-exist with each other. As a result, such a composite electrode may have, in some cases, the mechanical softness to permit both high energy densities and an improved current density as compared to, for example, a substantially pure metal electrode. |
| FILED | Thursday, January 11, 2024 |
| APPL NO | 18/410951 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/405 (20130101) Original (OR) Class H01M 10/36 (20130101) H01M 10/44 (20130101) H01M 10/0525 (20130101) H01M 2250/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274848 | Yandrasits et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | 3M Innovative Properties Company (St. Paul, Minnesota); Colorado School Of Mines (Golden, Colorado); GM Global Technology Operations LLC (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael A. Yandrasits (Hastings, Minnesota); Matthew J. Lindell (Woodbury, Minnesota); Arne Thaler (Neuss, Germany); Andrew M. Herring (Boulder, Colorado); ChulOong Kim (Lakewood, Colorado); Mei-Chen Kuo (Denver, Colorado); Craig S. Gittleman (West Bloomfield, Michigan) |
| ABSTRACT | Fluorinated ionomers (i.e., ion conducting polymers) that include a fluorinated polymer backbone with covalently bound pendent groups that include heteropolyacid (HP A) groups, or salts thereof, and perfluorosulfonic acid (PF SA) groups, or salts thereof, as well as polymer electrolyte membranes, fuel cells, and methods. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 18/566288 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 214/262 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/225 (20130101) C08J 2327/18 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1023 (20130101) H01M 8/1039 (20130101) Original (OR) Class H01M 2008/1095 (20130101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274855 | Chiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); 24M Technologies, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); 24M Technologies, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Yet-Ming Chiang (Weston, Massachusetts); W. Craig Carter (Jamaica Plain, Massachusetts); Bryan Y. Ho (Berkeley, California); Mihal Duduta (Somerville, Massachusetts); Pimpa Limthongkul (Boston, Massachusetts) |
| ABSTRACT | Redox flow devices are described in which at least one of the positive electrode or negative electrode-active materials is a semi-solid or is a condensed ion-storing electroactive material, and in which at least one of the electrode-active materials is transported to and from an assembly at which the electrochemical reaction occurs, producing electrical energy. The electronic conductivity of the semi-solid is increased by the addition of conductive particles to suspensions and/or via the surface modification of the solid in semi-solids (e.g., by coating the solid with a more electron conductive coating material to increase the power of the device). High energy density and high power redox flow devices are disclosed. The redox flow devices described herein can also include one or more inventive design features. In addition, inventive chemistries for use in redox flow devices are also described. |
| FILED | Thursday, March 14, 2024 |
| APPL NO | 18/605709 |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/72 (20190201) B60L 58/27 (20190201) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/20 (20130101) H01M 8/188 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101) Y02T 90/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274867 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Yubin Zhang (Warren, Michigan); Thomas A. Yersak (Royal Oak, Michigan); Aaron Ketchum (Sterling Heights, Michigan) |
| ABSTRACT | A semi-solid-state electrolyte system for use in a battery cell is provided. The semi-solid-state electrolyte system includes an oxysulfide solid-state electrolyte and a secondary electrolyte including a solvate ionic liquid. The semi-solid-state electrolyte system is configured for providing excellent ionic conductivity, supporting high current densities at a low stack pressure, and including excellent chemical stability. The oxysulfide solid-state electrolyte and the solvate ionic liquid are collectively configured for facilitating ion transfer between an anode of the battery cell and a cathode of the battery cell |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169686 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/056 (20130101) Original (OR) Class H01M 10/0562 (20130101) H01M 10/0568 (20130101) H01M 2300/0028 (20130101) H01M 2300/0071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274876 | Armstrong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Beth L. Armstrong (Oak Ridge, Tennessee); Gabriel M. Veith (Knoxville, Tennessee); Sergiy Kalnaus (Knoxville, Tennessee); Hsin Wang (Knoxville, Tennessee); Katie L. Browning (Oak Ridge, Tennessee); Kevin M. Cooley (Knoxville, Tennessee) |
| ABSTRACT | A battery includes an anode, a cathode, and a porous separator having a surface and percolating pores providing a porosity of from 20% to 80%. A passively impact resistant composite electrolyte includes an electrolyte and electrically non-conducting particles that enable shear thickening. The particles can have a polydispersity index of no greater than 0.1, an average particle size in a range of from 50 nm to 1 μm, and an absolute zeta potential of greater than ±40 mV. The shear thickening enabling particles can be from 10 wt. % to 40 wt. % of the total weight of the separator and shear thickening particles. Between 20-40 wt. % of the shear thickening enabling particles are located in the pores of the separator. |
| FILED | Tuesday, October 24, 2023 |
| APPL NO | 18/383268 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 41/88 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 50/431 (20210101) H01M 50/443 (20210101) H01M 50/491 (20210101) H01M 2300/0028 (20130101) H01M 2300/0085 (20130101) H01M 2300/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240275262 | Xing et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lei Xing (South Windsor, Connecticut); Suman Dwari (East Hartford, Connecticut); W. Warren Chen (Glastonbury, Connecticut) |
| ABSTRACT | A system can include a bi-directional converter circuit comprising a plurality of switches and a flying capacitor configured to experience a low voltage or a high voltage, and a control module operatively connected to the plurality of switches to control a state of the plurality of switches. The control module can be configured to receive a sense signal indicative of a flying capacitor voltage and to control the one or more switches of the plurality of switches to charge or discharge the flying capacitor to maintain a target voltage or target voltage range. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/127577 |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/00 (20190201) B60L 2200/10 (20130101) B60L 2210/00 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 41/00 (20130101) B64D 2221/00 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/0095 (20210501) Original (OR) Class H02M 3/33584 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240275269 | Du et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | Wei Du (Richland, Washington); Sheik Mohammad Mohiuddin (Richland, Washington) |
| ABSTRACT | This document describes systems and techniques for a control system for a grid-forming inverter. In aspects, a reactive power current-limiting subsystem, based on a measured reactive power, is configured to generate a first signal representing a magnitude of a modulation waveform presentable to a pulse-width modulator configured to direct transistors in the inverter of the grid-forming inverter. An active power current-limiting subsystem, based at least in part on a measured active power, is configured to generate a second signal representing a rotating phase angle of the modulation waveform presentable to the pulse-width modulator. The reactive power current-limiting subsystem and active power current-limiting subsystem are configured to cause an alternating current (AC) output of the grid-forming inverter to resume a nominal form subsequent to current being directed around one or more transistors in an inverter to prevent an excessive output current from flowing through the one or more transistors. |
| FILED | Thursday, April 18, 2024 |
| APPL NO | 18/639637 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/32 (20130101) Original (OR) Class H02M 7/5395 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240275493 | Williams |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian P. Williams (Oak Ridge, Tennessee) |
| ABSTRACT | A receiver configured to remove a bias of a homodyne detector is provided. The receiver produces at least one clone local oscillator (LO) pulse per LO pulse for the reference pulse and per LO pulse for the data-carrying pulse. Measurement made using clone LO pulses are used to compensate for the bias in reference measurements and data-carrying measurements. Clone LO pulses are produced when the reference pulses and the data-carrying pulses are not expected to be present at the homodyne detector. The bias corrected reference measurements may be used as feedback to maintain a timing synchronization of the LO for the reference pulse and the LO for the data-carrying pulse with the corresponding reference pulse and the data-carrying pulse, respectively and for polarization correction. The receiver may be incorporated into a continuous variable (CV) quantum key distribution (QKD) system. |
| FILED | Friday, February 09, 2024 |
| APPL NO | 18/437706 |
| CURRENT CPC | Transmission H04B 10/63 (20130101) Original (OR) Class H04B 10/70 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0852 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240275494 | Spiropulu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Maria Spiropulu (Pasadena, California); Venkata Ramana Raju Valivarthi (Pasadena, California) |
| ABSTRACT | Quantum teleportation is essential for many quantum information technologies, including long-distance quantum networks. Using fiber-coupled devices, including state-of-the-art low-noise superconducting nanowire single-photon detectors and off-the-shelf optics, we achieve conditional quantum teleportation of time-bin qubits at the telecommunication wavelength of 1536.5 nm. We measure teleportation fidelities of ≥9% that are consistent with an analytical model of our system, which includes realistic imperfections. To demonstrate the compatibility of our setup with deployed quantum networks, we teleport qubits over 22 km of single-mode fiber while transmitting qubits over an additional 22 km of fiber. Our systems, which are compatible with emerging solid-state quantum devices, provide a realistic foundation for a high-fidelity quantum Internet with practical devices. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/073245 |
| CURRENT CPC | Transmission H04B 10/70 (20130101) Original (OR) Class H04B 10/0795 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 7/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240276870 | BLACKBURN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Lee BLACKBURN (Golden, Colorado); Matthew Peter HAUTZINGER (Golden, Colorado); Matthew Craig BEARD (Denver, Colorado); Joseph Matthew LUTHER (Boulder, Colorado) |
| ABSTRACT | The present disclosure relates to a device that includes a first layer that includes a first perovskite that includes a first cation (A), a second cation (B), and first anion (X), a second layer that includes a second perovskite that includes a third cation (A′), a fourth cation (B′), and a second anion (X′), and a third layer that includes a two-dimensional (2D) material, where the third layer is physically positioned between the first layer and the second layer, and the third layer minimizes or eliminates the transfer of at least one of A, A′, B, B′, X, or X′ between the first layer and the second layer. |
| FILED | Thursday, February 15, 2024 |
| APPL NO | 18/442276 |
| CURRENT CPC | Organic electric solid-state devices H10K 30/20 (20230201) H10K 30/40 (20230201) H10K 71/12 (20230201) H10K 71/50 (20230201) H10K 85/30 (20230201) H10K 85/50 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20240268733 | Buller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as Represented by the Secretary of the Army (Fort Detrick, Maryland); The Secretary of State for Defence of the United Kingdom of Great Britain and Northern Ireland (London, Greater London, United Kingdom) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Jonathan Buller (Douglas, Massachusetts); Simon K. Delves (Rowlands Castle, Hampshire, United Kingdom) |
| ABSTRACT | In a general form, a running complexity analysis is computed for the skin temperature and heart rate measures as they both provide different views of the control of the thermoregulatory system. Initial Tsk and HR complexities at rest may form a baseline or normalization factor used to individualize the system. In at least one embodiment, the ratio of HR complexity to Tsk complexity is an indication of the individual's thermoregulatory strain level with one implementation for the thermoregulatory strain index. |
| FILED | Friday, July 01, 2022 |
| APPL NO | 18/567105 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) Original (OR) Class A61B 5/02055 (20130101) A61B 5/02405 (20130101) A61B 5/6804 (20130101) A61B 2562/0271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269270 | ANOSOVA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SANOFI PASTEUR INC. (Swiftwater, Pennsylvania); GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| ASSIGNEE(S) | SANOFI PASTEUR INC. (Swiftwater, Pennsylvania); GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| INVENTOR(S) | Natalie ANOSOVA (Lexington, Massachusetts); Salvador Fernando AUSAR (Markham, Canada); Catherine BERRY (Lyon, France); Florence BOUDET (Lyon, France); Thomas BREUER (Wavre, Belgium); Danilo CASIMIRO (Harleysville, Pennsylvania); Roman M. CHICZ (Belmont, Massachusetts); Gustavo DAYAN (Bethlehem, Pennsylvania); Guy DE BRUYN (Bushkill Township, Pennsylvania); Carlos DIAZGRANADOS (Wind Gap, Pennsylvania); Tong-Ming FU (Philadelphia, Pennsylvania); Marie GARINOT (Lyon, France); Lorry GRADY (Simsbury, Connecticut); Sanjay GURUNATHAN (Bethlehem, Pennsylvania); Kirill KALNIN (Pelham, New Hampshire); Nikolai KHRAMTSOV (Branford, Connecticut); Valérie LECOUTURIER (Chazay d'Azergues, France); Nausheen RAHMAN (North York, Canada); Sophie RUIZ (Lyon, France); Stephen SAVARINO (Saylorsburg, Pennsylvania); Saranya SRIDHAR (London, United Kingdom); Indresh K. SRIVASTAVA (Marlborough, Connecticut); James TARTAGLIA (Nazareth, Pennsylvania); Timothy TIBBITTS (East Greenwich, Rhode Island) |
| ABSTRACT | Provided are novel vaccines for prophylactic treatment of SARS-COV-2 infections and COVID-19 and methods of making the vaccines, wherein the vaccines contain an oil-in-water emulsion comprising tocopherol and squalene. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 18/042637 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 39/215 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/55566 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0601 (20130101) C12N 7/00 (20130101) C12N 2770/20022 (20130101) C12N 2770/20034 (20130101) C12N 2770/20071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269348 | Cullen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); John C. O'Donnell (Bryn Mawr, Pennsylvania); Erin M. Purvis (Philadelphia, Pennsylvania); Anh Le (Philadelphia, Pennsylvania); Qunzhou Zhang (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided herein is a method of obtaining astrocytes from gingiva-derived mesenchymal stem cells (GDMSC). Also disclosed herein are systems comprising a biocompatible construct and a plurality of astrocytes obtained from a method disclosed herein and methods of making and using the same. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 18/566373 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3604 (20130101) A61L 27/3675 (20130101) A61L 27/3895 (20130101) Original (OR) Class A61L 2430/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) C12N 2501/11 (20130101) C12N 2501/115 (20130101) C12N 2501/135 (20130101) C12N 2506/1392 (20130101) C12N 2533/54 (20130101) C12N 2533/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269468 | EDGERTON et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); University of Louisville Research Foundation, Inc. (Louisville, Kentucky); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victor Reggie EDGERTON (Los Angeles, California); Roland R. ROY (Playa Vista, California); Yury GERASIMENKO (Los Angeles, California); Joel W. BURDICK (Pasadena, California); Susan J. HARKEMA (Louisville, Kentucky); Jonathan HODES (Louisville, Kentucky); Yu-Chong TAI (Pasadena, California); Mandheerej S. NANDRA (Pasadena, California); Claudia A. ANGELI (Louisville, Kentucky); Thomas Anthony DESAUTELS (Pasadena, California) |
| ABSTRACT | A system and methods are disclosed for enabling or improving control of cardiovascular and/or vasomotor autonomic functions in a patient having a neurologically derived paralysis or a nervous system disorder. |
| FILED | Monday, April 15, 2024 |
| APPL NO | 18/635518 |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0237 (20130101) A61H 1/0274 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/0553 (20130101) A61N 1/0556 (20130101) A61N 1/3616 (20130101) A61N 1/36003 (20130101) A61N 1/36103 (20130101) Original (OR) Class Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 21/00181 (20130101) A63B 22/0235 (20130101) A63B 69/0064 (20130101) A63B 2213/004 (20130101) A63B 2220/805 (20130101) A63B 2230/60 (20130101) Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2270/0421 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269680 | Ririe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Biofire Defense, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kirk Max Ririe (Salt Lake City, Utah); David E. Jones (Layton, Utah); Christopher Paul Pasko (Salt Lake City, Utah); Anson Cole Chamberlain (American Fork, Utah); Derek David (Salt Lake City, Utah); Aaron Wernerehl (Salt Lake City, Utah); Jonathan Allen Bruns (Salt Lake City, Utah) |
| ABSTRACT | Instruments, methods, and kits are disclosed for performing fast thermocycling. |
| FILED | Thursday, April 04, 2024 |
| APPL NO | 18/627417 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 7/525 (20130101) Original (OR) Class B01L 2200/0647 (20130101) B01L 2300/18 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/1816 (20130101) B01L 2300/1822 (20130101) B01L 2300/1827 (20130101) B01L 2300/1861 (20130101) B01L 2400/0481 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269841 | Wandzel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arthur Richard Wandzel (Orchard Lake, Michigan); Stefanie Tellex (Providence, Rhode Island) |
| ABSTRACT | A system and method of operating a mobile robot to perform tasks includes representing a task in an Object-Oriented Partially Observable Markov Decision Process model having at least one belief pertaining to a state and at least one observation space within an environment, wherein the state is represented in terms of classes and objects and each object has at least one attribute and a semantic label. The method further includes receiving a language command identifying a target object and a location corresponding to the target object, updating the belief associated with the target object based on the language command, driving the mobile robot to the observation space identified in the updated belief, searching the updated observation space for each instance of the target object, and providing notification upon completing the task. In an embodiment, the task is a multi-object search task. |
| FILED | Wednesday, December 20, 2023 |
| APPL NO | 18/391580 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1661 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270762 | BURNS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Venatorx Pharmaceuticals, Inc. (Malvern, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher J. BURNS (Malvern, Pennsylvania); Denis DAIGLE (Street, Maryland); Guo-Hua CHU (Exton, Pennsylvania); Jodie HAMRICK (New Holland, Pennsylvania); Steven A. BOYD (Chester Springs, Pennsylvania); Allison L. ZULLI (Chesterbrook, Pennsylvania); Stephen M. CONDON (Glenmoore, Pennsylvania); Cullen L. MYERS (Phoenixville, Pennsylvania); Zhenrong XU (Chalfont, Pennsylvania); Tsuyoshi UEHARA (Berwyn, Pennsylvania); Nathan LINE (Royersford, Pennsylvania) |
| ABSTRACT | Described herein are certain boron-containing compounds, compositions, preparations and their use as modulators of the transpeptidase function of bacterial penicillin-binding proteins and as antibacterial agents. In some embodiments, the compounds described herein inhibit penicillin-binding proteins. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections. |
| FILED | Friday, March 25, 2022 |
| APPL NO | 18/563292 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/2013 (20130101) A61K 9/2018 (20130101) A61K 9/2054 (20130101) A61K 9/2059 (20130101) A61K 9/4825 (20130101) A61K 9/4858 (20130101) A61K 31/69 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class C07F 9/6596 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270796 | Cui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (BETHESDA, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xinle Cui (Gaithersburg, Maryland); Clifford M. Snapper (Potomac, Maryland) |
| ABSTRACT | Provided are antigenic compositions and uses thereof that include at least two human herpesvirus (HHV) polypeptides involved in mediating HHV binding, fusion, and entry into host cells, such as gp350, gH, gL, and gB, or nucleic acids encoding the polypeptides. The two HHV polypeptides comprise any combination of: a gB polypeptide; a gp350 polypeptide; a gL polypeptide; and a gH polypeptide, and optionally any one or more of the following polypeptides: gp42, gM, gN, gl, gC, gE, gD, ORF68, BMRF-2, BDLF2, UL128, UL130, UL131A, and gpK8.1. Also disclosed are methods of inducing an immune response or treating or preventing O an HHV infection in a subject by administering to the subject at least two of the HHV polypeptides or nucleic acid(s) encoding the same. Methods of passively transferring immunity using high-titer anti-HHV antibodies or immune cells are also disclosed. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/494219 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/25 (20130101) A61K 39/245 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/22 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16034 (20130101) C12N 2710/16071 (20130101) C12N 2710/16134 (20130101) C12N 2710/16171 (20130101) C12N 2710/16234 (20130101) C12N 2710/16271 (20130101) C12N 2710/16334 (20130101) C12N 2710/16371 (20130101) C12N 2710/16634 (20130101) C12N 2710/16671 (20130101) C12N 2710/16734 (20130101) C12N 2710/16771 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270812 | Zang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xingxing Zang (New York, New York); Jordan M. Chinai (Bronx, New York); Murali Janakiram (Brooklyn, New York); Steven C. Almo (Pelham, New York); Andras Fiser (New York, New York) |
| ABSTRACT | Provided are methods of treating an HHLA2-bearing tumor in a subject with a fusion protein comprising an IgV-like domain of a TMIGD2 sufficient to treat the HHLA2-bearing tumor. A fusion protein comprising an IgV-like domain of a TMIGD2 and related compositions and encoding nucleic acids are also provided. |
| FILED | Friday, January 05, 2024 |
| APPL NO | 18/405839 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/70503 (20130101) Original (OR) Class C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270814 | Deniger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| INVENTOR(S) | Drew C. Deniger (Houston, Texas); Steven A. Rosenberg (Potomac, Maryland); Anna Pasetto (Asker, Norway); Rami Yoseph (Gaithersburg, Maryland); Winifred M. Lo (Norfolk, Virginia); Yong-Chen Lu (Little Rock, Arkansas); Maria R. Parkhurst (Ellicott City, Maryland); Paul F. Robbins (Chevy Chase, Maryland); Parisa Malekzadeh (Norfolk, Virginia) |
| ABSTRACT | Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated human p53. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Wednesday, February 21, 2024 |
| APPL NO | 18/583139 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270851 | Ho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Mitchell Ho (Urbana, Maryland); Glenn Merlino (Vienna, Virginia); Dan Li (Rockville, Maryland); Hejiao English (Columbia, Maryland); Chi-Ping Day (Rockville, Maryland) |
| ABSTRACT | Single-domain shark variable new antigen receptor (VNAR) monoclonal antibodies that specifically bind programmed death-ligand 1 (PD-L1) are described. The PD-L1-specific VNAR antibodies are capable of binding PD-L1-expressing tumor cells from human, mouse and canine origin. Immune cells expressing chimeric antigen receptors (CARs) developed using the VNAR antibodies can be used to kill PD-L1-positive tumor cells, for example in animal models of liver cancer and breast cancer. |
| FILED | Monday, June 06, 2022 |
| APPL NO | 18/567990 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4631 (20230501) A61K 39/464402 (20230501) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2827 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/52 (20130101) C07K 2317/565 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270918 | Prabhakar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pavana Prabhakar (Madison, Wisconsin); Hridyesh Raj Tewani (Madison, Wisconsin) |
| ABSTRACT | Provided are methods of fabricating flexible syntactic foam objects from precursor powders comprising thermoplastic elastomer particles and hollow particles using selective laser sintering (SLS) with a porous/discontinuous internal structure. The method may comprise illuminating a region in a layer of a precursor powder comprising thermoplastic elastomer particles and hollow particles with a laser beam of a SLS to convert the region to a porous, sintered region comprising the hollow particles and a solid thermoplastic elastomer matrix having a surface that defines pores distributed throughout the porous, sintered region. The syntactic foam objects and articles of manufacture comprising the syntactic foam objects are also provided. |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/439978 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) B33Y 80/00 (20141201) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/232 (20130101) Original (OR) Class C08J 2315/00 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/28 (20130101) C08K 2201/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270953 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qiming Zhang (University Park, Pennsylvania); Xin Chen (University Park, Pennsylvania) |
| ABSTRACT | Disclosed herein are electro-mechanical polymer compositions comprising a ferroelectric polymer chain having a plurality of functional halogen monomer units. At least one of the plurality of functional halogen monomer units can comprise a fluorinated alkyne monomer unit. The electro-mechanical polymer compositions can have an electromechanical coupling factor of about 88% or greater and a piezoelectric coefficient of −1000 pm/V or less. Also disclosed herein are methods of making the same. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 18/565790 |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 27/16 (20130101) Original (OR) Class C08L 2203/20 (20130101) C08L 2205/02 (20130101) C08L 2205/035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270964 | LEAR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin J. LEAR (University Park, Pennsylvania); Robert J. FORTENBAUGH (University Park, Pennsylvania); Kaitlin HAAS (Langhorne, Pennsylvania) |
| ABSTRACT | Thermosetting formulations useful for forming bulk structures such as in additive manufacturing can include (a) a compound including reactive functional groups, (b) a curing agent having functional groups reactive with the reactive functional groups of the compound, and (c) a photothermally active material. Such formulations can be cured by applying actinic radiation to the formulation. |
| FILED | Thursday, October 19, 2023 |
| APPL NO | 18/490614 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Original (OR) Class C08L 2203/30 (20130101) C08L 2205/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270995 | REN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shenqiang REN (Williamsville, New York); Aaron SHENG (Buffalo, New York); Saurabh KHUJE (Amherst, New York) |
| ABSTRACT | Provided are conductive slurries with copper nanoplates. The copper nanoplates may be functionalized with formate groups and/or graphene or a graphene material. The slurries may be used as conductive inks, which may be used in 3D printing applications. Also provided are methods of making and using same. |
| FILED | Wednesday, May 25, 2022 |
| APPL NO | 18/564076 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/037 (20130101) C09D 11/52 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271072 | Desanti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles L. Desanti (Columbus, Ohio); Ryan W. Daly (Columbus, Ohio); David Charles Seibert, JR. (Columbus, Ohio); Patrick Norris (Columbus, Ohio); John Bartholomew (Columbus, Ohio); Sherry K. Blight (Columbus, Ohio) |
| ABSTRACT | A biological culture unit comprises a chamber body and a valve plate. The chamber body has defined therein a growth chamber and an aliquot chamber. The valve plate is disposed on the top surface of the chamber body and is movable to define selectable configurations of the biological culture unit for: (1) loading the growth chamber; (3) transferring an aliquot from the growth chamber to the aliquot chamber via a path defined within the biological culture unit in the transfer position; and (4) extracting the aliquot from the aliquot chamber. The selectable positions may further include (2) a growth position, and (5) a termination position for putting a termination agent into the growth and aliquot chambers. The valve plate may further include a neutralizer port that is aligned with the aliquot chamber in the loading position, for loading a neutralizing agent into the aliquot chamber. |
| FILED | Wednesday, April 03, 2024 |
| APPL NO | 18/625358 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class C12M 23/34 (20130101) C12M 23/40 (20130101) C12M 27/18 (20130101) C12M 29/10 (20130101) C12M 41/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271102 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xi Ren (Wexford, Pennsylvania); Piyumi Wijesekara (Pittsburgh, Pennsylvania); Amir Barati Farimani (Pittsburgh, Pennsylvania); Prakarsh Yadav (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods and materials for making and using apical-out ciliated organoids (e.g., apical-out airway organoids) are provided herein. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 18/568091 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0688 (20130101) Original (OR) Class C12N 2500/02 (20130101) C12N 2501/727 (20130101) C12N 2513/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271158 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel G. Anderson (Framingham, Massachusetts); Robert Alexander Wesselhoeft (Boston, Massachusetts); Piotr S. Kowalski (CORK, Ireland) |
| ABSTRACT | Circular RNA and methods and constructs for engineering circular RNA are disclosed. In some embodiments, the circular RNA includes the following elements arranged in the following sequence: a) an adjacent exon sequence of a 3′ Group I self-splicing intron-exon, b) an internal ribosome entry site (IRES), c) a protein coding region or noncoding region, and d) an adjacent exon sequence of a 5′ Group I self-splicing intron-exon. |
| FILED | Friday, March 15, 2024 |
| APPL NO | 18/607256 |
| CURRENT CPC | Peptides C07K 16/2803 (20130101) C07K 2317/31 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2015/859 (20130101) C12N 2015/8518 (20130101) C12N 2800/70 (20130101) C12N 2800/107 (20130101) C12N 2800/202 (20130101) C12N 2840/55 (20130101) C12N 2840/60 (20130101) C12N 2840/203 (20130101) C12N 2999/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271181 | KUGELMAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey R. KUGELMAN (New Market, Maryland); Peter A. LARSON (Frederick, Maryland); Raina KUMAR (Ashburn, Virginia); Mariano SANCHEZ-LOCKHART (New Market, Maryland) |
| ABSTRACT | Provided herein are methods for next generation sequencing a target using universal adapter technologies and identifying and reducing error by distinguishing the signals from sequencing the target based on the location on the flow cell of the signals from sequencing the sample identifying region(s) of the adapters. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 18/266692 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6876 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271584 | FRANKLIN |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arnez FRANKLIN (New Albany, Ohio) |
| ABSTRACT | In an approach to active engine idle control, an apparatus comprises: an accelerator module interface; an engine control module (ECM) interface; a computer readable storage media; and a controller. The controller is configured to: determine an engine speed target for a vehicle engine in revolutions per minute (RPM) based on an electrical load on the vehicle; determine a voltage curve for one or more position sensors of an accelerator module in the vehicle; determine a voltage target for the ECM for each position sensor of the one or more position sensors; and responsive to a first signal that the apparatus is engaged and a second signal that the vehicle is stopped, set an input voltage to the ECM at the voltage target for each of the one or more position sensors. |
| FILED | Wednesday, April 24, 2024 |
| APPL NO | 18/644224 |
| CURRENT CPC | Controlling Combustion Engines F02D 41/083 (20130101) Original (OR) Class F02D 41/0225 (20130101) F02D 2200/602 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/0825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271586 | Arumugam |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raghuvaran Arumugam (Daventry, United Kingdom) |
| ABSTRACT | Systems and apparatuses include a lubrication system having an engine piston defining a gudgeon pin aperture, a piston pooling cavity extending radially outward from the gudgeon pin aperture, a piston cooling gallery, and a piston lubrication passage. The piston lubrication passage is in fluid communication with the piston cooling gallery and the piston pooling cavity. The piston further includes a pin journal received in the gudgeon pin aperture of the engine piston and defining a journal aperture in fluid communication with the piston pooling cavity and a journal pooling cavity in fluid communication with the journal aperture. A gudgeon pin is received within the gudgeon pin aperture adjacent the pin journal, which provides fluid communication between the journal pooling cavity and the gudgeon pin. |
| FILED | Monday, December 11, 2023 |
| APPL NO | 18/535887 |
| CURRENT CPC | Lubricating of Machines or Engines in General; Lubricating Internal Combustion Engines; Crankcase Ventilating F01M 1/08 (20130101) F01M 1/16 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 3/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272052 | Choi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wonjune Choi (Tempe, Arizona); Maxwell Kulak (Mesa, Arizona); Wonmo Kang (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Wonjune Choi (Tempe, Arizona); Maxwell Kulak (Mesa, Arizona); Wonmo Kang (Scottsdale, Arizona) |
| ABSTRACT | A method and device for electro-thermo-mechanical tensile testing of wires is disclosed. The device includes a sample frame having upper and lower parts, with the upper part coupled to the lower part through a plurality of sacrificial supports, the upper and lower parts each having an electrical contact pad. The upper and lower parts are electrically non-conductive. The device also includes a wire sample with tracking beads, the wire sample affixed to the upper and lower parts such that the electrical contact pads of the upper and lower parts are communicatively coupled through the wire sample. The device also includes a piezo actuator coupled to the upper part, a weight coupled to the lower part, a power supply configured to pass a current through the wire sample, an electronic balance beneath the weight, and a digital camera pointed at the tracking beads of the wire sample. |
| FILED | Thursday, August 17, 2023 |
| APPL NO | 18/451746 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/08 (20130101) Original (OR) Class G01N 3/068 (20130101) G01N 2203/0017 (20130101) G01N 2203/028 (20130101) G01N 2203/0051 (20130101) G01N 2203/0075 (20130101) G01N 2203/0647 (20130101) G01N 2203/0676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272213 | Shivaram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Krishna Shivaram (Torrance, California); Phung N. Phan (Simi Valley, California); Bronson Riley Edralin (Carson, California) |
| ABSTRACT | A capacitive sensor and capacitive sensing method including a driver device having a first input configured to receive a clock signal, a second input configured to receive a charging voltage, a third input configured to receive a common-mode voltage, and an output; a first capacitor configured to be sensed, having a first terminal connected to the output of the driver device and a second terminal; and a receiver device having a first input configured to receive the clock signal, a second input connected to the second terminal of the first capacitor, and a third input configured to receive the common mode voltage. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169417 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 27/2605 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272251 | Foley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Twinleaf LLC (Plainsboro, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elizabeth L. Foley (Plainsboro, New Jersey); Thomas W. Kornack (Plainsboro, New Jersey); Lucia A. Rathbun (Princeton, New Jersey); Nancy G. Ford (Bordentown, New Jersey) |
| ABSTRACT | Aspects of a pulsed pump magnetometer improve upon previous pulsed pump magnetometers and gradiometers with the following features: the pumping is aided with a pulsed field coil parallel to the pump light, the pump laser module uses a pulse driver circuit integrated into the sensor, the pump laser module uses a wavelength selective element integrated in the laser module but separate from the emitter, and the sensor geometry is arranged so that the dead axis can be easily reoriented by rotating the long axis of the sensor. A preferred sensor geometry, with the pump axis perpendicular to the long edge of the sensor, allows a sensor to be easily rotated to avoid a low signal condition. |
| FILED | Wednesday, April 10, 2024 |
| APPL NO | 18/631958 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272271 | Pratt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas G Pratt (South Bend, Indiana); Luke Saladis (South Bend, Indiana) |
| ABSTRACT | A system and method for detecting targets with radar signals are disclosed which include a receiver configured to receive a radar signal and generate a first return vector having four elements representing four channels of a full-polarimetric radar reading, and a four-dimensional polarization filter applied to the first return vector, the four-dimensional polarization filter configured to arrange the first return vector in a column of four elements according to polarimetric components associated with of respective transmit/receive channels, take an inner product of a selected vector with the column, derive a projection coefficient by dividing the inner product by a magnitude of the selected vector, and produce an output by subtracting a product of the projection coefficient and the selected vector from the column. |
| FILED | Monday, February 12, 2024 |
| APPL NO | 18/439375 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/025 (20130101) G01S 7/0231 (20210501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272272 | Pratt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas G Pratt (South Bend, Indiana); Luke Saladis (South Bend, Indiana); Robert D Kossler (South Bend, Indiana) |
| ABSTRACT | A system and method for detecting targets with radar signals are disclosed which include a receiver configured to receive a radar signal on orthogonally-polarized channels and generate a receiver return vector from the received radar signal, a range filter configured to filter reflections in the receiver return vector at a selected range bin, and a polarization filter configured to filter an identified interference signal from a return of the range filter. |
| FILED | Monday, February 12, 2024 |
| APPL NO | 18/439384 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/0231 (20210501) Original (OR) Class G01S 7/354 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272449 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Fan Xu (West Lafayette, Indiana); Fang Huang (West Lafayette, Indiana); Donghan Ma (West Lafayette, Indiana) |
| ABSTRACT | A method of in situ point spread function (PSF) retrieval is disclosed which includes encoding 3D location of molecules into PSFs, receiving molecule-generated images containing PSFs, segmenting the images into sub-PSF, initializing template PSFs from a pupil function, determining a statistical measure of a predetermined function between the sub- and template PSFs, associating each of the sub-PSFs with a template PSF, aligning and averaging the sub-PSF, applying a phase retrieval algorithm to the averaged sub-PSFs to update the pupil function, regenerating the template PSFs, repeating until a difference between a new and a prior generation pupil function is below a predetermined threshold, generating in situ PSFs from the last pupil function, and applying a maximum likelihood estimation algorithm based on the in situ PSFs and the sub-PSF to thereby generate lateral and axial locations of molecules. |
| FILED | Monday, April 15, 2024 |
| APPL NO | 18/636195 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/367 (20130101) G02B 26/0825 (20130101) G02B 27/58 (20130101) Original (OR) Class G02B 27/0068 (20130101) Image Data Processing or Generation, in General G06T 2207/10056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273058 | KIM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Hun-seok KIM (Ann Arbor, Michigan); David BLAAUW (Ann Arbor, Michigan); Kuan-Yu CHEN (Ann Arbor, Michigan) |
| ABSTRACT | A domain adaptive systolic-array-processor is presented with 256 programmable cores in a 12 nm CMOS for wireless communication workloads. The domain adaptive processor uses a globally homogeneous but locally heterogeneous architecture, decode-less reconfiguration instructions for data streaming, single-cycle data communication between functional units (FUs), and lightweight nested-loop control. This disclosure shows how configuration flexibility and fast program loading allows a wide range of communication workloads to be mapped and swapped in sub-μs, supporting continually evolving communication standards such as 5G. The domain adaptive processor achieves 507 GMACs/J and a peak performance of 264 GMACs. |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/439936 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30065 (20130101) G06F 15/8046 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273341 | DEY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shawon DEY (Reno, Nevada); Dan SHEN (Germantown, Maryland); Zola DONOVAN (Rome, New York); Genshe CHEN (Germantown, Maryland); Hao XU (Reno, Nevada); Erik BLASCH (Arlington, Virginia) |
| ABSTRACT | The present disclosure provides a method, a device, and a storage medium for decentralized optimal control for a large-scale multi-agent system. The method includes initializing errors to obtain an initialized error of each of an actor NN, a critic NN and a mass NN; initializing error thresholds to obtain an initialized error threshold of each of the actor NN, the critic NN and the mass NN; and if the initialized error of each of the actor NN, the critic NN and the mass NN is greater than or equal to a corresponding initialized error threshold, calculating weights of each of the actor NN, the critic NN and the mass NN, and updating the actor NN, the critic NN, and the mass NN; and calculating errors of each of the actor NN, the critic NN and the mass NN, and updating the actor NN, the critic NN, and the mass NN. |
| FILED | Thursday, February 02, 2023 |
| APPL NO | 18/163860 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/045 (20230101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273407 | Khaleghi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Behnam Khaleghi (La Jolla, California); Jaeyoung Kang (San Diego, California); Hanyang Xu (San Diego, California); Justin Morris (San Diego, California); Tajana Rosing (San Diego, California); Uday Bhanu Sharma Mallappa (Sunnyvale, California); Haichao Yang (La Jolla, California); Monil Shah (Austin, Texas) |
| ABSTRACT | Disclosed herein are techniques and architectures for encoding data within a hyperdimensional computing (HDC) framework, enabling the transformation of input data into high-dimensional vector space representations. Embodiments herein facilitate the segmentation of data into multiple windows, selection of level hypervectors corresponding to data elements, application of permutation operations for positional encoding, and execution of binary operations to synthesize window hypervectors. The aggregation of such window hypervectors yields an encoded hypervector that encapsulates a representation of the original data in HDC space. The disclosed embodiments are adept at handling various data types, including textual, image, voice, or sensor data, providing for broad applicability and adaptability in encoding for hyperdimensional computing applications. |
| FILED | Wednesday, February 14, 2024 |
| APPL NO | 18/441318 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274118 | Pascoguin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bienvenido Melvin L. Pascoguin (San Diego, California); Brittany Lynn (San Diego, California); Michael P. Ross (San Diego, California) |
| ABSTRACT | A laser-induced plasma (LIP) sound generator comprising: a laser beam and a first beam splitter configured to split the laser into a plurality of sub-laser beams such that each sub-laser beam creates a LIP at a respective focal point, wherein each focal point lies within an imaginary sphere having a radius that is less than half of a desired sound wavelength such that acoustic fields of the LIPs add together as if from a single point source. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/168735 |
| CURRENT CPC | Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 15/046 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) H01S 3/0085 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 23/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240275044 | LIPSON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michal LIPSON (New York, New York); Christopher Thomas PHARE (New York, New York); You-Chia CHANG (New York, New York); Steven A. MILLER (New York, New York) |
| ABSTRACT | An optical apparatus comprising an optical switch array comprising a plurality of optical switches configured to selectively route light through one or more of a plurality of waveguides, a plurality of emitters, wherein at least one emitter of the plurality of emitters is disposed in communication with the one or more of the plurality of waveguides and configured to receive light and cause at least a portion of the light to exit the waveguide, and a lens disposed to receive light exiting the one or more of a plurality of waveguides via the at least one emitter, wherein the lens is configured to direct the received light as an optical output, and wherein the position of the at least one emitter relative to the lens facilitates beam steering of the optical output. |
| FILED | Wednesday, April 03, 2024 |
| APPL NO | 18/626158 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/10 (20130101) G01S 17/42 (20130101) G01S 17/89 (20130101) Antennas, i.e Radio Aerials H01Q 3/38 (20130101) Original (OR) Class H01Q 3/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240275070 | Bastin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nantenna LLC (Melbourne, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary L. Bastin (Palm Bay, Florida) |
| ABSTRACT | The teachings of the present application generally for an ultra-high frequency (UHF) antenna assembly which provides for a smaller package size with the same or better efficiency as a much larger antenna, particularly between 100 MHz to 500 MHZ. Particularly, through the combination of components and structures for implementing frequency selective surfaces (FSS) and high impedance structures (HIS) in combination with an anisotropic magneto-dielectric material, the present teachings provide for the use of both lower and higher frequency techniques through the operational frequency band and miniaturization, accurately improving the performance of UHF satellite communication antennas. Specifically improving performance in narrowband, with increases in efficiency, bandwidth, and lowered elevation angle radiation characteristics. |
| FILED | Monday, August 08, 2022 |
| APPL NO | 18/681417 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 9/285 (20130101) H01Q 15/006 (20130101) H01Q 19/108 (20130101) Original (OR) Class H01Q 19/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240275415 | Shin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sanghoon Shin (Burke, Virginia); Hans Haucke (Accokeek, Maryland) |
| ABSTRACT | Methods and apparatuses for attenuating an interferer signal are provided. The apparatus includes a tunable filter and an autonomous tracking control circuit. The tunable filter is constructed to receive signals within a frequency bandwidth and includes a plurality of tunable bandpass filters with respective bandpass filter responses. The tunable filter has a band reject filter response that is dependent upon the bandpass filter responses. The autonomous tracking control circuit is constructed to track an interferer signal within the frequency bandwidth and perform voltage control on the plurality of tunable bandpass filters to alter the band reject filter response of the tunable filter such that the interferer signal is attenuated in an output of the tunable filter. |
| FILED | Wednesday, February 14, 2024 |
| APPL NO | 18/441922 |
| CURRENT CPC | Transmission H04B 1/1036 (20130101) Original (OR) Class H04B 1/1607 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240275737 | ROSEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Andrew ROSEN (Westford, Massachusetts); Chelsea Georgan (Cambridge, Massachusetts); Jon Aho (Somerville, Massachusetts); Venkatesh Ramaswamy (Westford, Massachusetts) |
| ABSTRACT | A system for establishing and maintaining a communications network includes: one or more programs including instructions for: receiving a first set of data associated with a first set of communication links, the first set of communication links configured to establish connection between devices; receiving a second set of data associated with a second set of communication links; receiving a determination of whether one or more communication links of the first set satisfy a pre-determined quality level; receiving a determination of whether one or more communication links of the second set satisfy the pre-determined quality level; receiving a selection from the one or more communication links of the second set that have been determined to satisfy the pre-determined quality level; and connecting the devices via the selected one or more communication links if one or more communication links of the first set is determined to not satisfy the pre-determined quality level. |
| FILED | Thursday, April 18, 2024 |
| APPL NO | 18/639405 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/5025 (20130101) H04L 43/087 (20130101) H04L 43/0811 (20130101) H04L 47/70 (20130101) Original (OR) Class Wireless Communication Networks H04W 76/10 (20180201) H04W 88/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240276886 | Pei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Qibing Pei (Los Angeles, California); Erin Askounis (San Jose, California); Ye Shi (Los Angeles, California) |
| ABSTRACT | A dielectric elastomer including a crosslinked network comprising a polypropylene oxide) unit on a network chain or a pendant group. In another example, the dielectric elastomer is stacked in a multi-layer dielectric elastomer structure comprising two adjacent dielectric elastomer layers, a layer of a. conductive network sandwiched between the two adjacent dielectric elastomer layers, and. a polymer layer binding the conductive network and the two adjacent dielectric elastomer layers. The dielectric elastomer can be used as an actuator or artificial muscle in a variety of robotic, haptic, or wearable devices. In one or more examples, the dielectric elastomer has a strain, including an area strain, greater than least 100% in response to the electric field less than 150 Volts per micron and converts at least 10% of inputted electrical energy to mechanical work. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 18/560669 |
| CURRENT CPC | Electric solid-state devices not otherwise provided for H10N 30/206 (20230201) H10N 30/506 (20230201) H10N 30/857 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20240268372 | Uygun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mustafa Korkut Uygun (Newton, Massachusetts); Siavash Raigani (Cambridge, Massachusetts); Shannon Tessier (Framingham, Massachusetts); Heidi Yeh (Lincoln, Massachusetts); Casie A. Pendexter (Rockland, Massachusetts); Stephanie EJ Cronin (Nashville, Tennessee); Reinier De Vries (Boston, Massachusetts); Mehmet Toner (Charlestown, Massachusetts) |
| ABSTRACT | The present disclosure relates to a perfusate, a storage solution, or a recovery solution having an apoptosis inhibitor. Also disclosed are various uses, including preserving a biological tissue sample and mitigating ischemia-reperfusion injury in such samples. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 18/560000 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) A01N 1/0226 (20130101) Original (OR) Class A01N 1/0284 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240268396 | Jin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hailing Jin (Oakland, California) |
| ABSTRACT | Compositions comprising an antifungal RNA and a lipid vesicle are provided, wherein the antifungal RNA comprises a double-stranded RNA, a small RNA, or a small RNA duplex. The lipid vesicle may be, for example, a plant-derived vesicle or an artificial vesicle containing a tertiary amine cationic lipid. For example, the RNA may target a dicer-like (DCL) gene or a long terminal repeat (LTR) region of a fungal pathogen such as Botrytis or Verticillium. Methods for increasing pathogen resistance in plants are also described. |
| FILED | Thursday, June 16, 2022 |
| APPL NO | 18/570033 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/04 (20130101) A01N 63/60 (20200101) Original (OR) Class Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 3/00 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240268742 | HAMADA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Murata Manufacturing Co., Ltd. (Nagaokakyo-shi, Japan); North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shu HAMADA (Nagaokakyo-shi, Japan); Alper BOZKURT (Morrisville, North Carolina); James REYNOLDS (Graham, North Carolina); Parvez AHMMED (Raleigh, North Carolina) |
| ABSTRACT | An implantable device is provided that includes a tubular body with at least one open end, defining an inner space, a cap closing the at least one open end and having an inner surface on one side and an outer surface on the other side, the inner surface facing the inner space, and a circuit board being placed in the inner space, having an active surface, a board electrode disposed on the active surface, and a wireless communication circuit to communicate outside of a body, biological information obtained via the board electrode. Moreover, a recess and an inner electrode are disposed on the inner surface of the cap, and the circuit board is disposed in the recess, and the inner electrode is electrically connected to the board electrode. An outer electrode is disposed on the outer surface of the cap and is electrically connected to the inner electrode. |
| FILED | Tuesday, April 16, 2024 |
| APPL NO | 18/636894 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/29 (20210101) Original (OR) Class A61B 5/0031 (20130101) A61B 5/02405 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240268746 | Yanik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ahmet Ali Yanik (Santa Cruz, California); Ahsan Habib (Santa Cruz, California); Neil Hardy (Santa Cruz, California) |
| ABSTRACT | A system includes a light source configured to illuminate a target site in a brain with a near infrared light having a wavelength from about 1000 nm to about 1700 nm. The system also includes a plurality of nanoparticle probes disposed at the target site, each of the nanoparticle probes may include: a core having a substantially spherical shape, a conductive shell disposed over the core, and an electrochromic polymer coating disposed over the conductive shell. The system may further include an image sensor configured to receive backscattered light from the plurality of nanoparticles illuminated by the near infrared light. The plurality of nanoparticle probes is configured to shift their backscattering spectrum in response to a change in an electrical field at the target site. |
| FILED | Monday, June 13, 2022 |
| APPL NO | 18/568909 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/4064 (20130101) Original (OR) Class A61B 2562/0285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269163 | KENT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas); The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); The Trustees of Indiana University (Bloomington, Indiana) |
| INVENTOR(S) | Thomas A. KENT (Houston, Texas); Paul J. DERRY (Houston, Texas); Kenneth R. OLSON (Berrien Springs, Michigan) |
| ABSTRACT | A method of treating a Down syndrome (DS) subject with functional or at risk of decline of organ systems associated with accelerated aging due to over-production of H2S is disclosed. That method contemplates administering a pharmaceutical composition containing a H2S-reducing effective amount of hydrophilic polymer-substituted oxidized carbon nanoparticles (OCNPs) and an optional potentiating amount of lipoic acid or dihydrolipoic acid dissolved or dispersed in a physiologically acceptable diluent to the subject. The pharmaceutical composition can be administered parenterally as a liquid or per os as a solid or liquid. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 18/567972 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/385 (20130101) A61K 31/765 (20130101) Original (OR) Class A61K 47/6921 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269164 | Toscano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Universidad de Buenos Aires (Buenos Aires, Argentina); CONSEJO NACIONAL DE INVESTGACIONES CIENTFICAS Y TECNICAS CONICET (Buenos Aires, Argentina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Pasquale Toscano (Baltimore, Maryland); Jessica Zarenkiewicz (Baltimore, Maryland); Guillermo Alejandro Carrone (Buenos Aires, Argentina); Agostina Maria Mazzeo (Buenos Aires, Argentina); Emesto Jose Marceca (Buenos Aires, Argentina); Juan Pellegrino (Buenos Aires, Argentina); Fabio Ariel DOCTOROVICH (Buenos Aires, Argentina); Sebastian Suarez (Buenos Aires, Argentina); Paola E. Vargas (Buenos Aires, Argentina) |
| ABSTRACT | Disclosed is a method for generating nitroxyl (HNO) in the gas phase, the method comprising contacting a solid base-catalyzed HNO donor with a gaseous base; or a solid acid-catalyzed HNO donor with a gaseous acid; to form HNO in the gas phase and methods of treating a disease or condition responsive to HNO therapy with the HNO formed in the gas phase. |
| FILED | Tuesday, May 17, 2022 |
| APPL NO | 18/560588 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Original (OR) Class Non-metallic Elements; Compounds Thereof; C01B 21/20 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269348 | Cullen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); John C. O'Donnell (Bryn Mawr, Pennsylvania); Erin M. Purvis (Philadelphia, Pennsylvania); Anh Le (Philadelphia, Pennsylvania); Qunzhou Zhang (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided herein is a method of obtaining astrocytes from gingiva-derived mesenchymal stem cells (GDMSC). Also disclosed herein are systems comprising a biocompatible construct and a plurality of astrocytes obtained from a method disclosed herein and methods of making and using the same. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 18/566373 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3604 (20130101) A61L 27/3675 (20130101) A61L 27/3895 (20130101) Original (OR) Class A61L 2430/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) C12N 2501/11 (20130101) C12N 2501/115 (20130101) C12N 2501/135 (20130101) C12N 2506/1392 (20130101) C12N 2533/54 (20130101) C12N 2533/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269351 | Reddy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sashank Reddy (Baltimore, Maryland); Russell Martin (Baltimore, Maryland); Xiaowei Li (Townson, Maryland); Calvin Chang (Baltimore, Maryland); Kevin Colbert (Baltimore, Maryland); Hai-Quan Mao (Baltimore, Maryland) |
| ABSTRACT | A soft tissue device can incorporate a composite material comprising a gel and at least one nanostructure disposed within the gel. A soft tissue device can further incorporate biologically active materials such as cells, tissues. A method for healing a soft tissue defect while promoting soft tissue regeneration can include applying a soft tissue device to a soft tissue defect, wherein the composite material includes a gel and a nanostructure disposed within the gel. A method for manufacturing a soft tissue device for use in healing soft tissue defects can include providing a gel, disposing nanofibers within the gel, and a biologically active material. |
| FILED | Thursday, August 24, 2023 |
| APPL NO | 18/237744 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/20 (20130101) A61L 27/44 (20130101) A61L 27/48 (20130101) A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) Original (OR) Class A61L 27/3808 (20130101) A61L 27/3834 (20130101) A61L 27/3895 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2300/602 (20130101) A61L 2300/604 (20130101) A61L 2300/622 (20130101) A61L 2400/06 (20130101) A61L 2400/12 (20130101) A61L 2430/34 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/19 (20130101) A61M 2202/08 (20130101) A61M 2202/09 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269645 | SHIRMAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Metalmark Innovations, PBC (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Metalmark Innovations, PBC (Cambridge, Massachusetts) |
| INVENTOR(S) | Tanya SHIRMAN (Winchester, Massachusetts); Sissi LIU (Arlington, Massachusetts); Elijah SHIRMAN (Winchester, Massachusetts) |
| ABSTRACT | In one aspect, a composition is disclosed that includes an agglomeration of a plurality of porous microparticles forming a hierarchically porous material structure. The porous microparticles can be formed of a biogenic and/or a synthetic material. In some embodiments, a plurality of binder can be distributed among the microparticles to facilitate the agglomeration of the plurality of the microparticles. |
| FILED | Friday, February 16, 2024 |
| APPL NO | 18/444001 |
| CURRENT CPC | Separation B01D 39/2068 (20130101) B01D 2239/0407 (20130101) B01D 2239/0485 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/14 (20130101) Original (OR) Class B01J 20/2803 (20130101) B01J 20/28007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269651 | Petruska et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Melissa A. Petruska (Newtown, Connecticut); Jeffrey F. Roeder (Brookfield, Connecticut); Trevor E. James (Plantsville, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut); Thomas S. Spoonmore (Norwalk, Connecticut); Robert T. Henderson, III (New Milford, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Melissa A. Petruska (Newtown, Connecticut); Jeffrey F. Roeder (Brookfield, Connecticut); Trevor E. James (Plantsville, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut); Thomas S. Spoonmore (Norwalk, Connecticut); Robert T. Henderson, III (New Milford, Connecticut) |
| ABSTRACT | Monolithic composite photocatalysts for fluid purification are disclosed. The monolithic composite photocatalysts comprise a photoactive nanocrystal component and a non-photoactive porous support. Photocatalytic fluid purification systems that contact an impurity-containing fluid with the subject monolithic composite photocatalysts are also disclosed. The monolithic composite photocatalysts may be affixed to or embedded in scaffold structures to promote fluid flow through a fluid purification system and contact with the monolithic composite photocatalysts. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 17/481279 |
| CURRENT CPC | Separation B01D 53/865 (20130101) B01D 53/8687 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) Original (OR) Class B01J 35/39 (20240101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/50 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269841 | Wandzel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arthur Richard Wandzel (Orchard Lake, Michigan); Stefanie Tellex (Providence, Rhode Island) |
| ABSTRACT | A system and method of operating a mobile robot to perform tasks includes representing a task in an Object-Oriented Partially Observable Markov Decision Process model having at least one belief pertaining to a state and at least one observation space within an environment, wherein the state is represented in terms of classes and objects and each object has at least one attribute and a semantic label. The method further includes receiving a language command identifying a target object and a location corresponding to the target object, updating the belief associated with the target object based on the language command, driving the mobile robot to the observation space identified in the updated belief, searching the updated observation space for each instance of the target object, and providing notification upon completing the task. In an embodiment, the task is a multi-object search task. |
| FILED | Wednesday, December 20, 2023 |
| APPL NO | 18/391580 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1661 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270645 | Fini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Elham Fini (Phoenix, Arizona); Albert Hung (Tempe, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elham Fini (Phoenix, Arizona); Albert Hung (Tempe, Arizona) |
| ABSTRACT | Modifying siliceous material includes combining siliceous material and bio-oil to yield a mixture, and polymerizing the bio-oil in the mixture to yield hydrophobic siliceous material, wherein a hydrophobicity of the hydrophobic siliceous material exceeds a hydrophobicity of the siliceous material. The resulting composition includes a multiplicity of hydrophobic particles, wherein each hydrophobic particle comprises a polymeric bio-oil-derived coating on a core comprising siliceous material, and a hydrophobicity of the polymeric bio-oil-derived coating exceeds a hydrophobicity of the corresponding core. |
| FILED | Thursday, February 15, 2024 |
| APPL NO | 18/442675 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 20/04 (20130101) C04B 20/1037 (20130101) Original (OR) Class C04B 2103/0052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270664 | Gounder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rajamani P. Gounder (West Lafayette, Indiana); Elizabeth E. Rogers (Dresser, Wisconsin); Songhyun Lee (West Lafayette, Indiana); Evan Sowinski (West Lafayette, Indiana) |
| ABSTRACT | MFI zeolite and methods for converting alkenes to higher liquid products. The method includes contacting one or more alkenes having about 2 to about 12 carbon atoms with a MFI zeolite having a silicon to aluminum ratio (Si:Al) of about 20 to about 100 and a crystallite size of about 0.001 μm to about 0.1 μm; and oligomerizing the one or more alkenes in the presence of the MFI zeolite to form an oligomer having 4 to 26 carbon atoms. |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/440016 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/40 (20130101) B01J 35/77 (20240101) B01J 37/30 (20130101) Acyclic or Carbocyclic Compounds C07C 2/12 (20130101) Original (OR) Class C07C 2529/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270800 | SHAH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Donald Danforth Plant Science Center (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dilip M. SHAH (St. Louis, Missouri); Meenakshi TETORYA (St. Louis, Missouri) |
| ABSTRACT | Antimicrobial CaNCR peptide variants or CaNCR peptide variant multimers are disclosed along with compositions comprising the CaNCR peptide variants or CaNCR peptide variant multimers and transgenic or genetically edited plants or microorganisms that express the CaNCR peptide variants or CaNCR peptide variant multimers to inhibit growth of pathogenic microbes. Such CaNCR peptide variants, or CaNCR peptide variant multimers, compositions, plants, and microorganisms can provide for inhibition of microbial growth in plants, processed plant products, animals, and humans. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 18/692138 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/50 (20200101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 3/00 (20210801) Preparations for Medical, Dental, or Toilet Purposes A61K 38/168 (20130101) Peptides C07K 14/415 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271096 | Kamp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy Kamp (Madison, Wisconsin); Yukihiro Saito (Okayama, Japan) |
| ABSTRACT | The present disclosure provides a method of generating right ventricle (RV) cardiomyocytes from pluripotent stem cells, populations of second heart field (SHF) cardiac progenitor cells and right ventricle (RV) cardiomyocytes produced by the method, a method of using these cells to study RV dysfunction related diseases, and a method of treating a subject with cardiac disease comprising administering to the patient the SHF cardiac progenitor cells or the RV cardiomyocytes. |
| FILED | Tuesday, February 13, 2024 |
| APPL NO | 18/440260 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class C12N 2501/33 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2503/00 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271247 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nien-Hwa Linda Wang (West Lafayette, Indiana); Hoon Choi (Miami, Florida); David Harvey (West Lafayette, Indiana) |
| ABSTRACT | A process disclosed herein is related to the isolation and purification of substantially pure chemicals, including silica gel, sodium silicate, aluminum silicate, iron oxide, and rare earth elements (or rare earth metals, REEs), from massive industrial waste coal ash. In one embodiment, the process includes a plurality of caustic extractions of coal ash at an elevated temperature, followed by an acidic treatment to dissolve aluminum silicate and REEs. The dissolved aluminum silicate is precipitated out by pH adjustment as a solid product while REEs remain in the solution. REEs are captured and enriched using an ion exchange column. Alternatively, the solution containing aluminum silicate and REEs is heated to produce silica gel, which is easily separated from the enriched REEs solution. REEs are then isolated and purified from the enriched solution to afford substantially pure individual REE by a ligand-assisted chromatography. Additionally, a simplified process using one caustic extraction and one acidic extraction with an ion exchange process was also investigated and optimized to afford a comparable efficiency. |
| FILED | Tuesday, January 09, 2024 |
| APPL NO | 18/407664 |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/14 (20130101) C01B 33/26 (20130101) C01B 33/32 (20130101) Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 13/00 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 7/0693 (20130101) C01F 11/02 (20130101) C01F 11/24 (20130101) C01F 17/271 (20200101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/02 (20130101) C01G 49/06 (20130101) C01G 49/10 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/08 (20130101) C22B 3/10 (20130101) C22B 3/42 (20130101) C22B 3/44 (20130101) C22B 3/065 (20130101) C22B 7/02 (20130101) C22B 7/007 (20130101) Original (OR) Class C22B 21/0023 (20130101) C22B 59/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271274 | Seal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sudipta Seal (Orlando, Florida); Parag Banerjee (Orlando, Florida); Udit Kumar (Orlando, Florida) |
| ABSTRACT | A ceria heterostructure may include one or more base materials and one or more ceria surface structures at least partially surrounding the one or more base materials, where defect states of the one or more ceria surface structures are reversibly controllable by controlling a stress on the one or more surface structures that is at least partially induced by the one or more base materials. |
| FILED | Friday, January 12, 2024 |
| APPL NO | 18/412083 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/405 (20130101) Original (OR) Class C23C 16/45525 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271936 | Puckett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Matthew Wade Puckett (Phoenix, Arizona); Jianfeng Wu (Tucson, Arizona); Steven Tin (Edina, Minnesota); Tiequn Qiu (Glendale, Arizona) |
| ABSTRACT | Techniques are provided for implementing and using a high quality factor travelling wave resonator configured to propagate a transverse magnetic mode optical signals and suppress transverse electric mode optical signals. The travelling wave resonator may be used in a resonator optical gyroscope. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/166665 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/661 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271937 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Jianfeng Wu (Tucson, Arizona); Tiequn Qiu (Glendale, Arizona); Matthew Wade Puckett (Phoenix, Arizona) |
| ABSTRACT | Techniques are provided for diminishing bias error, in a resonator optical gyroscope, due to an undesired, parasitic optical mode which is orthogonal to a desired optical mode. Energy levels of the undesired, parasitic mode can be diminished utilizing polarizing beam splitters each of which suppresses energy of the undesired, parasitic mode of a clockwise or a counterclockwise optical signal more than energy of the desired mode of the CW optical signal. Optionally, one or more components of a travelling wave resonator system are configured to suppress energy of the undesired, parasitic mode of a clockwise and/or a counterclockwise optical signal more than energy of the desired mode of the respective optical signal(s). Optionally, the desired optical mode is either a transverse magnetic (TM) mode or a transverse electric (TE) mode, and the undesired, parasitic optical mode is respectively the TE mode or the TM mode. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/166792 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/722 (20130101) G01C 19/727 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272549 | Hosein |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ian D. Hosein (Minoa, New York) |
| ASSIGNEE(S) | Syracuse University (Syracuse, New York) |
| INVENTOR(S) | Ian D. Hosein (Minoa, New York) |
| ABSTRACT | A polymer film having a non-planar surface defined by a series of surface bumps and a plurality of nanoparticles in the polymer film, wherein the nanoparticles are more concentrated proximately to surface and in the surface bumps to provide anti-wetting and anti-stick properties. The polymer coating is formed by casting a thin layer of a photopolymerizable polymer precursor having a plurality of nanoparticles over a transparent substrate and then irradiating the thin layer from below with a periodic light field so that the photopolymerizable polymer precursor forms a polymer with a non-planar surface and the nanoparticles are concentrated proximately to the non-planar surface as a result of phase separation. The resulting film can be washed with a solvent to remove any uncured polymer and peeled away from the substrate for use as an anti-stick and anti-wetting coating. |
| FILED | Tuesday, June 07, 2022 |
| APPL NO | 18/567876 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 22/1006 (20200201) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/029 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272614 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Qiang Huang (Los Angeles, California); Yuanxiang Wang (Los Angeles, California); Cesar Ruiz Torres (Los Angeles, California) |
| ABSTRACT | An apparatus, system, and method is provided for predicting 3D shape deformation in additive manufacturing. A convolution learning framework for shape deviation modeling provides joint learning for a wide class of 3D shapes including both spherical and polyhedral shapes. A 3D cookie-cutter function can effectively capture the unique pattern of the shape deformation for polyhedral shapes. Since 3D freeform shapes can be approximated as a combination of spherical and polyhedral patches, the extended convolution learning framework builds a foundation for modeling and predicting the quality of 3D freeform shapes. By changing the kernel function and considering new distance measures for points from different shapes, the spatial correlations among different shapes can be correctly incorporated. The predicted deformation may be used to offset the machine instructions to an additive manufacturing machine to ameliorate deformation. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 18/567311 |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/02 (20141201) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/4099 (20130101) Original (OR) Class G05B 2219/49023 (20130101) Image Data Processing or Generation, in General G06T 17/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273204 | Mishra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prabhat Kumar Mishra (Gainesville, Florida); Zhixin Pan (Gainesville, Florida) |
| ABSTRACT | Various embodiments of the present disclosure provide hardware trojan detection using Shapley ensemble boosting. In one example, an embodiment provides for extracting a plurality of features related to hardware trojan detection from one or more circuit samples related to one or more circuits, training one or more machine learning models based at least in part on the plurality of features, modifying the one or more machine learning models based at least in part on a set of Shapley values to generate one or more enhanced machine learning models for hardware trojan detection related to the one or more circuits, and deploying the one or more enhanced machine learning models for the hardware trojan detection related to the one or more circuits. |
| FILED | Friday, February 09, 2024 |
| APPL NO | 18/437674 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/71 (20130101) G06F 21/566 (20130101) Original (OR) Class G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 20/20 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273350 | Hsieh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yung-Ting Hsieh (Piscataway, New Jersey); Dario Pompili (Hillsborough, New Jersey) |
| ABSTRACT | An analog neural network circuit includes at least one fewer layers than a number of expected layers of a neural network such that at least two cycles of feeding back outputs and applying weights occur to complete all the expected layers of the neural network. A control circuit, for example implemented using an analog oscillator, provides timing signals to control signal paths, including a feedback signal path to reuse circuitry of a layer for the at least two cycles. An analog memory is coupled to store an output of the circuitry of the layer. The analog memory is controllably coupled as part of the feedback signal path to the circuitry of the layer. |
| FILED | Thursday, February 15, 2024 |
| APPL NO | 18/442811 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/065 (20230101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273678 | VALM et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alex M. VALM (Albany, New York); Yunlong FENG (Slingerlands, New York) |
| ABSTRACT | There is set forth herein, according to one embodiment, receiving a real image representing a target in which endmembers are present in unknown proportions; and searching and optimizing an abundance matrix space expressed in an unmixing formula that references together with the abundance matrix space, image information of the real image and an endmember spectral profile matrix that specifies spectral profiles for a set of differentiated reference endmembers; wherein as a result of the searching and optimizing the abundance matrix space, there is identified a set of unmixed real image endmembers and abundances associated to the unmixed real image endmembers. |
| FILED | Tuesday, January 30, 2024 |
| APPL NO | 18/427449 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273733 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Roack, Arkansas) |
| INVENTOR(S) | Anh Pha Nguyen (Fayetteville, Arkansas); Khoa Luu (Technology, Arkansas) |
| ABSTRACT | Systems and methods for three-dimensional object tracking across cameras are disclosed. The method includes receiving detection outcomes generated by a three-dimensional object detector from a plurality of synchronized camera inputs, responsive to the receiving, maintaining a graph having nodes and weighted edges between at least a portion of the nodes, executing appearance modeling of the nodes via a self-attention layer of a graph transformer network, and executing motion modeling of the nodes. |
| FILED | Saturday, February 10, 2024 |
| APPL NO | 18/438449 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/20 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/44 (20220101) G06V 10/761 (20220101) G06V 2201/07 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273870 | Luu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| INVENTOR(S) | Khoa Luu (Fayetteville, Arkansas); Anh Pha Nguyen (Fayetteville, Arkansas); Yi Liang (Fayetteville, Arkansas); Miaoqing Huang (Fayetteville, Arkansas) |
| ABSTRACT | Systems and methods for training a network via a source domain of labeled image samples and a target domain of unlabeled image samples are disclosed. The method includes determining, for each domain of the source domain and the target domain, an entropy loss related to the domain, determining an adversarial loss for a domain discriminator configured to predict whether a given input belongs to the source domain or the target domain, and executing domain adaptation training of the network using the entropy loss for the source domain, the entropy loss for the target domain, and the adversarial loss. |
| FILED | Friday, February 09, 2024 |
| APPL NO | 18/438089 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/194 (20170101) Image or Video Recognition or Understanding G06V 10/764 (20220101) G06V 10/771 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240273949 | Ramani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Karthik Ramani (West Lafayette, Indiana); Tianyi Wang (West Lafayette, Indiana); Xun Qian (West Lafayette, Indiana) |
| ABSTRACT | A system and method for authoring and implementing context-aware applications (CAPs) are disclosed. The system and method enables users to record their daily activities and then build and deploy customized CAPs onto augmented reality platforms in which automated actions are performed in response to user-defined human actions. The system and method utilizes an integrated augmented reality platform composed of multiple camera systems, which allows for non-intrusive recording of end-users' activities and context detection while authoring and implementing CAPs. The system and method provides an augmented reality authoring interface for browsing, selecting, and editing recorded activities, and creating flexible CAPs through spatial interaction and visual programming. |
| FILED | Monday, April 15, 2024 |
| APPL NO | 18/635112 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/011 (20130101) Image Data Processing or Generation, in General G06T 7/215 (20170101) G06T 13/40 (20130101) G06T 19/006 (20130101) Image or Video Recognition or Understanding G06V 20/20 (20220101) G06V 40/23 (20220101) G06V 40/28 (20220101) Original (OR) Class G06V 40/103 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274812 | Teng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaowei Teng (Durham, New Hampshire); Sathya N. Jagadeesan (Worcester, Massachusetts) |
| ABSTRACT | An iron anode employs an electrolyte for generating an anode reaction to convert between Iron II and Iron III ions, denoted by Fe(OH)2 and FeOOH, rather than tending towards formation of highly stable Fe3O4, which can tend to cause “dead” regions in the battery. A suitable battery chemistry includes iron-air and other iron metal batteries operable with an aqueous electrolyte and employing oxygen and water cathodes. The iron anode battery employs inexpensive available iron, rather than more expensive and/or volatile materials used in Li-ion and lead-acid batteries. An aqueous electrolyte formed from sodium hydroxide and silicates, optionally with potassium or chloride salts, forms an anode reaction with nanostructured iron oxide particles in a safe and stable battery chemistry which is readily scalable for grid storage. |
| FILED | Wednesday, February 14, 2024 |
| APPL NO | 18/441249 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/52 (20130101) Original (OR) Class H01M 10/26 (20130101) H01M 12/08 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274831 | PAI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rahul Nagesh PAI (Philadelphia, Pennsylvania); Vibha KALRA (Garnet Valley, Pennsylvania); Michel W. BARSOUM (Moorestown, New Jersey); Hussein O. BADR (Philadelphia, Pennsylvania) |
| ABSTRACT | By combining two-dimensional (2D) transition metal oxide and/or carbo-oxides with sulfur, one can form cathodes for use in Li—S batteries, which batteries in turn exhibit high capacity and other attractive characteristics. Accordingly, provided herein are methods, comprising: forming an admixture that comprises sulfur, a 2D transition metal carbo-oxide, and optionally a conductive material. Also provided are electrodes, comprising sulfur, a 2D transition metal carbo-oxide, and optionally a conductive material. Further provided are energy cells, the energy cell comprising a first electrode according to the present disclosure. Additionally provided are methods, the methods comprising discharging an energy cell according to the present disclosure or charging an energy cell according to the present disclosure. Also provided are electrical devices, comprising an energy cell according to the present disclosure. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 18/568358 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/623 (20130101) H01M 4/628 (20130101) Original (OR) Class H01M 10/052 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20240274874 — Anionic Polymers, Electrolytes Comprising the Same, and Methods of Manufacture Thereof
| US 20240274874 | Zdilla et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mike Zdilla (Wallingford, Pennsylvania); Stephanie Wunder (Chadds Ford, Pennsylvania) |
| ABSTRACT | The invention provides a novel anionic polymer useful as a solid electrolyte in a lithium battery. The electrolyte matrix provides directional, flexible, polymeric ion channels with 100% lithium conduction with low-to-no affinity of the matrix for the lithium ion, in part due to the low concentration or absence of lone pair electrons in the anionic polymer. |
| FILED | Thursday, February 29, 2024 |
| APPL NO | 18/591852 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240276226 | Closas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pau Closas (Boston, Massachusetts); Guillermo Wilfredo Hernandez (Boston, Massachusetts); Gerald Mycko LaMountain (Malden, Massachusetts) |
| ABSTRACT | Embodiments define a method and apparatus for determining a geospatial location of an unlocated device communicatively coupled to a network while maintaining privacy. The unlocated device transmits a first encryption layer public enabling multiple other devices, including an assistant device, to employ the first encryption layer public key. The assistant device transmits a second encryption layer public key to the multiple other devices, and those devices return to the assistant device respective encrypted representations of geospatial locations encrypted by the first encryption layer public key and the second encryption layer public key. The assistant device decrypts the second layer encrypted representations of the geospatial locations with the second encryption layer secret key; and performs an averaging function on the representations of geospatial locations. The assistant device transmits the encrypted solution to the averaging function to the unlocated device, which decrypts the encrypted solution using the first encryption layer secret key. |
| FILED | Friday, December 22, 2023 |
| APPL NO | 18/395177 |
| CURRENT CPC | Wireless Communication Networks H04W 12/037 (20210101) H04W 12/63 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240276648 | Yi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ning Yi (University Park, Pennsylvania); Yuyan Gao (University Park, Pennsylvania); Antonino Lo Verso, Jr. (University Park, Pennsylvania); Jia Zhu (University Park, Pennsylvania); Daniel Erdely (University Park, Pennsylvania); Robert Lavelle (University Park, Pennsylvania); Huanyu Cheng (University Park, Pennsylvania) |
| ABSTRACT | The invention includes methods of forming electronic circuitry on a target surface using intense pulsed light-induced mass transfer (IPLMT) of metal nanoparticles (NPs) by applying a pliable mask to a target surface, coating a carrier film with metal NPs, mounting the carrier film to the target surface and over the pliable mask so that the pliable mask is sandwiched between the target surface and the metal NPs. and exposing the metal NPs to light energy to cause atoms of the metal NPs to evaporate and transport through openings of the pliable mask and condense on the target surface, producing a conductive pattern of condensed metal on the target surface. Certain implementations may utilize a kirigami-patterned pliable mask to enhance conformity to a freeform 3D target surface. In certain implementations, zinc (Zn) may be formed by IPLMT of Zn NPs to the target surface. |
| FILED | Wednesday, March 30, 2022 |
| APPL NO | 18/561934 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/28 (20210101) A61B 5/296 (20210101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) H05K 3/143 (20130101) Original (OR) Class H05K 3/146 (20130101) H05K 2203/083 (20130101) H05K 2203/0156 (20130101) H05K 2203/0557 (20130101) H05K 2203/1131 (20130101) H05K 2203/1173 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20240268279 | YANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ronggui YANG (Boulder, Colorado); Xiaobo YIN (Boulder, Colorado); Lihua SHEN (Idaho Falls, Idaho) |
| ABSTRACT | Improving photosynthesis and light capture increases crop yield and paves a sustainable way to meet the growing global food demand. A spectral-shifting microphotonic film is provided particularly for applications to improved plant growth, for example, as a greenhouse envelope. The spectral-shifting microphotonic film can be scalable manufactured for augmented photosynthesis. By breaking the intrinsic propagation symmetry of light, the photonic microstructures provided in the film can extract 89% of the internally generated light and deliver most of that into one direction towards photosynthetic organisms. The microphotonic film augments crop production (e.g., lettuce) by more than 20% in both indoor facilities with electric lighting and in a greenhouse with natural sunlight, providing a way to increase crop production efficiency in controlled environments. |
| FILED | Friday, June 17, 2022 |
| APPL NO | 18/569171 |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 7/06 (20130101) Original (OR) Class A01G 9/14 (20130101) Optical Elements, Systems, or Apparatus G02B 1/041 (20130101) G02B 3/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269199 | Aroian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raffi Van Aroian (Shrewsbury, Massachusetts); Kelly Flanagan (Boston, Massachusetts) |
| ABSTRACT | Compositions and methods for treating or reducing the severity or likelihood of occurrence of a parasitic worm infection in a humans and domestic animals are described. The compositions include inactivated recombinant bacteria expressing a Cry14Ab crystal protein in the cytosol of the bacterium. The composition may be provided in a form suitable for oral administration. Methods include administering a therapeutically effective amount of the composition to a human or domestic animal suffering from a parasitic worm infection. The composition may also be used as feed, feed supplement, or a waste treatment. |
| FILED | Wednesday, January 17, 2024 |
| APPL NO | 18/415118 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5089 (20130101) A61K 35/742 (20130101) Original (OR) Class A61K 38/164 (20130101) A61K 2035/115 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269623 | SHANGGUAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Compact Membrane Systems, Inc. (Newport, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ning SHANGGUAN (Cherry Hill, New Jersey); Robert D. LOUSENBERG (Wilmington, Delaware) |
| ABSTRACT | A fluorinated copolymer having pendant amide functionality is disclosed in an aspect herein. A membrane from the fluorinated copolymer having at least some of the pendant amide functionality hydrolyzed to pendant amine functionality is highly permeable to carbon dioxide and can be useful in the gas-separation layer of a thin-film composite membrane for the separation of carbon dioxide from nitrogen or methane. |
| FILED | Thursday, May 12, 2022 |
| APPL NO | 18/560648 |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 69/107 (20220801) B01D 71/32 (20130101) Original (OR) Class B01D 2256/10 (20130101) B01D 2256/245 (20130101) B01D 2257/504 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 226/02 (20130101) C08F 226/10 (20130101) C08F 234/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269651 | Petruska et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Melissa A. Petruska (Newtown, Connecticut); Jeffrey F. Roeder (Brookfield, Connecticut); Trevor E. James (Plantsville, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut); Thomas S. Spoonmore (Norwalk, Connecticut); Robert T. Henderson, III (New Milford, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Melissa A. Petruska (Newtown, Connecticut); Jeffrey F. Roeder (Brookfield, Connecticut); Trevor E. James (Plantsville, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut); Thomas S. Spoonmore (Norwalk, Connecticut); Robert T. Henderson, III (New Milford, Connecticut) |
| ABSTRACT | Monolithic composite photocatalysts for fluid purification are disclosed. The monolithic composite photocatalysts comprise a photoactive nanocrystal component and a non-photoactive porous support. Photocatalytic fluid purification systems that contact an impurity-containing fluid with the subject monolithic composite photocatalysts are also disclosed. The monolithic composite photocatalysts may be affixed to or embedded in scaffold structures to promote fluid flow through a fluid purification system and contact with the monolithic composite photocatalysts. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 17/481279 |
| CURRENT CPC | Separation B01D 53/865 (20130101) B01D 53/8687 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) Original (OR) Class B01J 35/39 (20240101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/50 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270589 | Cai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhiyong Cai (Madison, Wisconsin); Qiangu Yan (Madison, Wisconsin) |
| ABSTRACT | Methods of forming a metal-carbon composite body are provided which may comprise (a) subjecting a metallized biomass to pressure for a period of time to provide a compressed metallized biomass body, wherein the metallized biomass comprises a metallized biopolymer comprising a hydrocarbon backbone and a plurality of metallized functional groups distributed along the hydrocarbon backbone and covalently bound thereto; and (b) heating the compressed metallized biomass body according to a heating profile to carbonize the compressed metallized biomass body and provide a metal-carbon composite body comprising a covalently bound carbon matrix that extends in three dimensions to form a three-dimensional (3D) carbon network with metal distributed throughout the 3D carbon network. The metal-carbon composite bodies are also provided. |
| FILED | Friday, February 02, 2024 |
| APPL NO | 18/431086 |
| CURRENT CPC | Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 13/00 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/51 (20130101) C01P 2006/17 (20130101) C01P 2006/40 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270647 | Youngblood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Paul Youngblood (Crawforsville, Indiana); Jason Weiss (Corvallis, Oregon); Krishna Siva Teja Chopperla (Corvallis, Oregon); Sivakumar Ramanathan (Corvallis, Oregon) |
| ABSTRACT | Cement paste compositions including modified cellulose nanomaterials such as modified cellulose nanocrystals and modified cellulose nanofibers, are disclosed herein. In some embodiments, the cement paste compositions include from about 0.005 volume % to about 1.5 volume % modified cellulose nanomaterial. |
| FILED | Thursday, February 15, 2024 |
| APPL NO | 18/442689 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 20/1022 (20130101) C04B 20/1037 (20130101) C04B 20/1048 (20130101) C04B 20/1074 (20130101) C04B 24/386 (20130101) Original (OR) Class C04B 28/04 (20130101) C04B 2103/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270790 | BANNANTINE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INSTITUT PASTEUR (Paris Cedex 15, France); INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE L'ALIMENTATION ET L'ENVIRONNEMENT (Paris Cedex 07, France); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John P. BANNANTINE (Ames, Iowa); Gilles ETIENNE (Toulouse, France); Sylvie BAY (Paris, France); Franck BIET (Notre Dame D'Oe, France) |
| ABSTRACT | The present invention is directed to an isolated synthetic tripeptide of formula H-D-Phe-N-Methyl-L-Val-L-Ala-OMe (SEQ ID NO: 1), or a derivative thereof, and to the corresponding lipotripeptides, which are specific to Mycobacterium avium subsp. paratuberculosis (Map) S-type strain, as well as derivatives and conjugates thereof. The invention also concerns the use of these antigens in different methods and tests for detecting Map infection, especially by detecting humoral response and cell mediated response of infected animals. The invention is also directed to a genetic signature of Map and a mass spectrometry and NMR spectroscopy signature of Map presence or infection. |
| FILED | Friday, March 15, 2024 |
| APPL NO | 18/606817 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 47/60 (20170801) A61K 47/542 (20170801) Peptides C07K 5/0812 (20130101) Original (OR) Class C07K 7/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5695 (20130101) G01N 2333/57 (20130101) G01N 2333/5428 (20130101) G01N 2469/20 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20240268430 | KOZUBAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. KOZUBAL (Bozeman, Montana); Richard E. MACUR (Manhattan, Montana); Yuval C. AVNIEL (Missoula, Montana); Maximilian DeVane HAMILTON (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Thursday, April 11, 2024 |
| APPL NO | 18/632796 |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269841 | Wandzel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arthur Richard Wandzel (Orchard Lake, Michigan); Stefanie Tellex (Providence, Rhode Island) |
| ABSTRACT | A system and method of operating a mobile robot to perform tasks includes representing a task in an Object-Oriented Partially Observable Markov Decision Process model having at least one belief pertaining to a state and at least one observation space within an environment, wherein the state is represented in terms of classes and objects and each object has at least one attribute and a semantic label. The method further includes receiving a language command identifying a target object and a location corresponding to the target object, updating the belief associated with the target object based on the language command, driving the mobile robot to the observation space identified in the updated belief, searching the updated observation space for each instance of the target object, and providing notification upon completing the task. In an embodiment, the task is a multi-object search task. |
| FILED | Wednesday, December 20, 2023 |
| APPL NO | 18/391580 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1661 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240270980 | FARHAT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | West Virginia University Board of Governors on Behalf of West Virginia University (Morgantown, West Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tarek R. FARHAT (Beckley, West Virginia); Hasan M. El RIFAI (Daniels, West Virginia); Rana M. JISR (Daniels, West Virginia) |
| ABSTRACT | In one aspect, the disclosure relates to coated metal materials, e.g., a metal substrate such as a solid metal surface or a metal mesh, coated with a superhydrophobic coating comprising a first layer and a second layer as disclosed herein; methods of making the coated metal materials comprising the superhydrophobic coating; and products comprising the disclosed coated metals. In another aspect, the disclosure relates to an apparatus comprising a metal mesh coated with a superamphiphobic or superhydrophobic coating. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Monday, February 12, 2024 |
| APPL NO | 18/439554 |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1668 (20130101) Original (OR) Class C09D 127/18 (20130101) C09D 139/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/03 (20130101) G01N 21/33 (20130101) G01N 2021/0389 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271833 | Minas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Constantinos Minas (Niskayuna, New York); Ernst Wolfgang Stautner (Niskayuna, New York) |
| ABSTRACT | Example systems, methods, and apparatus are disclosed herein. Disclosed systems include a superconducting (SC) motor to power a propulsor of an aircraft and a liquid hydrogen (LH2) subcooling system including a primary flowline fluidly coupled to a cooling assembly of the SC motor, a secondary flowline fluidly coupled to the primary flowline, an expansion valve coupled to the secondary flowline, and a heat exchanger fluidly coupled to the primary flowline and the secondary flowline. Disclosed systems also include a fuel cell stack coupled to the primary flowline and the cooling assembly. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169655 |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/08 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 9/00 (20130101) F17C 2205/0323 (20130101) F17C 2221/012 (20130101) F17C 2223/0161 (20130101) F17C 2227/0135 (20130101) F17C 2227/0157 (20130101) F17C 2227/0339 (20130101) F17C 2250/0439 (20130101) F17C 2250/0636 (20130101) F17C 2265/066 (20130101) F17C 2270/0189 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 9/002 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0606 (20130101) H01M 8/04029 (20130101) H01M 8/04074 (20130101) H01M 8/04089 (20130101) H01M 8/04201 (20130101) H01M 8/04723 (20130101) H01M 8/04768 (20130101) H01M 2250/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240272091 | GASIEWSKI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado); THE SOIL MOISTURE COMPANY (Boulder, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Albin GASIEWSKI (Boulder, Colorado); Eryan DAI (Boulder, Colorado); Jack ELSTON (Boulder, Colorado); Maciej STACHURA (Boulder, Colorado); Michael HUROWITZ (Longmont, Colorado) |
| ABSTRACT | A method for determining soil moisture of a scene includes (i) generating a first antenna output in response to an upwelling thermal emission from the scene. (ii) generating a second antenna output in response to a downwelling thermal emission from sky above the scene. (iii) coupling the first antenna output and the second antenna output to yield a combined output having a quadrature phase difference between the first antenna output and the second antenna output. (iv) calculating a brightness-temperature difference based at least partially on the combined output. and (v) calculating a soil moisture based on soil-vegetation radiative transfer model using the brightness-temperature difference. |
| FILED | Monday, July 25, 2022 |
| APPL NO | 18/291190 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/04 (20130101) Original (OR) Class G01N 33/246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240274901 | Brown et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Of America as Represented By The Administrator Of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joshua L. Brown (Newport News, Virginia); Peter W. Spaeth (Yorktown, Virginia); William C. Schneck, III (Fort Monroe, Virginia); Matthew J. Godbold (Cayce, South Carolina); Daniel F. Perey (Yorktown, Virginia) |
| ABSTRACT | A registration method for digital radiography of thin flexible multilayer materials, which includes adding surface modifications to a product formed from thin flexible multilayer materials to create high contrast registration markers. The present approach is suited for products that would otherwise display few distinguishable features in high-resolution narrow field of view images. The registration markers are used to register and align a series of high-resolution narrow field of view images of separate portions of a thin, flexible, multilayer product. The aligned images may be digitally stitched together to form a high-resolution composite image of the whole product. The resulting composite image may allow nondestructive inspection to analyze changes to the internal structure of the product over time. The flexible multilayer materials with registration markers may be used in battery cell pouches, which permits tracking internal changes of a lithium-ion pouch cell battery over time. |
| FILED | Thursday, February 08, 2024 |
| APPL NO | 18/436734 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 7/001 (20130101) G06T 7/33 (20170101) G06T 2207/10116 (20130101) G06T 2207/20221 (20130101) G06T 2207/30108 (20130101) G06T 2207/30204 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/48 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 50/105 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20240268430 | KOZUBAL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. KOZUBAL (Bozeman, Montana); Richard E. MACUR (Manhattan, Montana); Yuval C. AVNIEL (Missoula, Montana); Maximilian DeVane HAMILTON (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Thursday, April 11, 2024 |
| APPL NO | 18/632796 |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240268698 | DOUSSAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | ALLAIRE DOUSSAN (WILDER, Vermont); RYAN HALTER (LYME, New Hampshire); ETHAN MURPHY (WHITE RIVER JUNCTION, Vermont) |
| ABSTRACT | A bioimpedance device for surgical cavities has pick-up electrodes surrounded by driving electrodes, each driving electrode having greater area than the pick-up electrodes, the electrode array coupled through an adjacent connector to an electronics module. The electronics module fits through laparoscopic ports. The electronics module includes a voltage controlled current source, multiplexing for driving electrodes, a force sensor, and voltage buffers, and couples to a data acquisition system coupled to a processor. The processor uses the apparatus to perform bioimpedance mapping of tissue. A method of mapping bioimpedance includes contacting tissue with the electrode array, sequentially driving at least one of the driving electrodes with an alternating current at frequencies between 100 and 1000000 hertz while reading the sense electrodes through analog to digital converters into the processor; using readings of the sense electrodes to generate a bioimpedance map of the tissue; the electrode array fitting through laparoscopic ports. |
| FILED | Friday, June 10, 2022 |
| APPL NO | 18/568940 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0536 (20130101) Original (OR) Class A61B 5/6843 (20130101) A61B 5/7264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269286 | Horsager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EOS Neuroscience, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan Horsager (Los Angeles, California); Kenneth Greenberg (Oakland, California); Benjamin C. Matteo (San Francisco, California); Edward S. Boyden (Chestnut Hill, Massachusetts); Douglas G. Ririe (Winston-Salem, North Carolina); James C. Eisenach (Winston-Salem, North Carolina); Christian Wentz (Cambridge, Massachusetts) |
| ABSTRACT | Provided are compositions and methods for the selective silencing of neurons in pain pathway by using a combination of inhibitory light-sensitive protein gene transfer and wavelength specific illumination. |
| FILED | Wednesday, August 23, 2023 |
| APPL NO | 18/454275 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 41/00 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Peptides C07K 14/37 (20130101) C07K 14/195 (20130101) C07K 14/215 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14143 (20130101) C12N 2810/6027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271866 | Dummer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Polarean, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew K. Dummer (Chapel Hill, North Carolina) |
| ABSTRACT | Cryo-collection systems are provided with an integrated cooler and heater thermally coupled to an accumulator. The cooler and the heater are electronically, automatically controlled to provide the cooling and then the heating to respectively collect/freeze, then thaw a collected gas, such as 129Xe, in the accumulator. |
| FILED | Tuesday, February 06, 2024 |
| APPL NO | 18/433767 |
| CURRENT CPC | Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 3/0276 (20130101) F25J 3/0685 (20130101) Original (OR) Class F25J 2205/20 (20130101) F25J 2215/36 (20130101) F25J 2270/904 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271867 | Dummer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Polarean, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew K. Dummer (Chapel Hill, North Carolina); Matthew Linford (Chapel Hill, North Carolina) |
| ABSTRACT | Cryo-collection systems are provided with a fluid flow paths to a chamber enclosing at least part of an accumulator to serially provide coolant liquid and heated liquid to provide the cooling and then the heating to respectively collect/freeze, then thaw a target gas, such as collected 129Xe, in the accumulator. |
| FILED | Tuesday, February 06, 2024 |
| APPL NO | 18/433770 |
| CURRENT CPC | Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 3/0685 (20130101) Original (OR) Class F25J 2210/42 (20130101) F25J 2215/36 (20130101) F25J 2280/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20240269149 | ADAMS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (IOWA CITY, Iowa); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (WASHINGTON, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (IOWA CITY, Iowa); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (WASHINGTON, District of Columbia) |
| INVENTOR(S) | Christopher M. ADAMS (Rochester, Minnesota); Steven D. KUNKEL (West Richland, Washington); Michael WELSH (Riverside, Iowa) |
| ABSTRACT | The invention provides a method for (a) increasing skeletal muscle mass; (b) reducing skeletal muscle atrophy; (c) increasing muscular strength; (d) promoting muscle growth; (e) decreasing muscle wasting; or (f) increasing strength per unit of muscle mass in an animal identified or having been identified to be in need of one or more of (a)-(f), the method comprising administering to the animal an effective amount of a compound of formula: or a stereoisomer, solvate, or pharmaceutically acceptable salt thereof, thereby accomplishing one or more of (a)-(f). |
| FILED | Tuesday, August 22, 2023 |
| APPL NO | 18/454012 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 31/56 (20130101) A61K 31/58 (20130101) Original (OR) Class A61K 31/215 (20130101) A61K 31/352 (20130101) A61K 31/353 (20130101) A61K 31/382 (20130101) A61K 31/404 (20130101) A61K 31/407 (20130101) A61K 31/435 (20130101) A61K 31/436 (20130101) A61K 31/437 (20130101) A61K 31/438 (20130101) A61K 31/473 (20130101) A61K 31/565 (20130101) A61K 31/4164 (20130101) A61K 31/4166 (20130101) A61K 31/4355 (20130101) A61K 31/4365 (20130101) A61K 31/4375 (20130101) A61K 31/4706 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 2600/136 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) G01N 2800/10 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269190 | SMITH et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (PHILADELPHIA, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | LACHLAN JAMES SMITH (Philadelphia, Pennsylvania); CHENGHAO ZHANG (Philadelphia, Pennsylvania) |
| ABSTRACT | Described are compositions containing isolated mammalian nucleus pulposus cells having an extracellular matrix (ECM)-generating phenotype and methods for making and using the disclosed compositions. The compositions disclosed herein are useful for treating back pain. |
| FILED | Tuesday, January 23, 2024 |
| APPL NO | 18/420721 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240269348 | Cullen et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Kacy Cullen (Media, Pennsylvania); John C. O'Donnell (Bryn Mawr, Pennsylvania); Erin M. Purvis (Philadelphia, Pennsylvania); Anh Le (Philadelphia, Pennsylvania); Qunzhou Zhang (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided herein is a method of obtaining astrocytes from gingiva-derived mesenchymal stem cells (GDMSC). Also disclosed herein are systems comprising a biocompatible construct and a plurality of astrocytes obtained from a method disclosed herein and methods of making and using the same. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 18/566373 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3604 (20130101) A61L 27/3675 (20130101) A61L 27/3895 (20130101) Original (OR) Class A61L 2430/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) C12N 2501/11 (20130101) C12N 2501/115 (20130101) C12N 2501/135 (20130101) C12N 2506/1392 (20130101) C12N 2533/54 (20130101) C12N 2533/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271215 | Schwartz et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David A. Schwartz (Denver, Colorado); Tasha E. Fingerlin (Aurora, Colorado); Weiming Zhang (Aurora, Colorado) |
| ABSTRACT | Disclosed are biomarkers, methods and assay systems for the identification of poor prognosis of interstitial pneumonia (pulmonary fibrosis) in an individual diagnosed with suspected of having interstitial pneumonia. |
| FILED | Wednesday, April 10, 2024 |
| APPL NO | 18/631414 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/12 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20240269163 | KENT et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas); The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); The Trustees of Indiana University (Bloomington, Indiana) |
| INVENTOR(S) | Thomas A. KENT (Houston, Texas); Paul J. DERRY (Houston, Texas); Kenneth R. OLSON (Berrien Springs, Michigan) |
| ABSTRACT | A method of treating a Down syndrome (DS) subject with functional or at risk of decline of organ systems associated with accelerated aging due to over-production of H2S is disclosed. That method contemplates administering a pharmaceutical composition containing a H2S-reducing effective amount of hydrophilic polymer-substituted oxidized carbon nanoparticles (OCNPs) and an optional potentiating amount of lipoic acid or dihydrolipoic acid dissolved or dispersed in a physiologically acceptable diluent to the subject. The pharmaceutical composition can be administered parenterally as a liquid or per os as a solid or liquid. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 18/567972 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/385 (20130101) A61K 31/765 (20130101) Original (OR) Class A61K 47/6921 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20240271097 | COLAS et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexandre COLAS (La Jolla, California); Maria Azzurra MISSINATO (San Diego, California); Michael S. YU (Cambridge, Massachusetts) |
| ABSTRACT | This present disclosure provides methods and pharmaceutical compositions for cell reprogramming and a pharmaceutical composition comprising the reprogrammed cells. In certain embodiments, the method of reprogramming a cell comprises reducing the expression of at least one barrier gene selected from the group consisting of ATF7IP, JUNB, ZNF207, Sp7, FOXA1, HEXIM2, SMARCA5, SOX15, CHST2 or NCEH1, or if the barrier gene is ATF7IP or SOX15, then the expression of a second barrier gene is also reduced. In another embodiment, the reprogramming method comprises reducing the expression of at least two barrier genes selected from the group consisting of ATF7IP, JUNB, ZNF207 and Sp7. |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 18/568172 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) A61K 35/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 5/0657 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2501/999 (20130101) C12N 2506/28 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20240271993 | Gaitan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Gaitan (North Potomac, Maryland); Jon Clement Geist (Olney, Maryland); Benjamin James Reschovsky (Cabin John, Maryland); Akobuije Douglas Eziani Chijioke (Silver Spring, Maryland) |
| ABSTRACT | A calibration apparatus for calibrating a laser Doppler vibrometer includes: a frequency shifter stage that: receives, from the laser Doppler vibrometer, primary laser light; produces frequency shifted light; communicates the frequency shifted light to a reflector; receives frequency shifted light reflected by the reflector; produces secondary light; and communicates the secondary light to the laser Doppler vibrometer, such that the laser Doppler vibrometer receives the secondary light from the frequency shifter stage and produces a synthetic velocity shift from the secondary light; and the reflector that receives and reflects the frequency shifted light back to the frequency shifter stage. |
| FILED | Thursday, January 11, 2024 |
| APPL NO | 18/410271 |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, August 15, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20240815.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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