FedInvent™ Patents

Patent Details for Tuesday, January 02, 2024 

This page was updated on Wednesday, January 03, 2024 at 12:58 AM GMT

Department of Health and Human Services (HHS) 

US 11856945 Singamaneni et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Srikanth Singamaneni (St. Louis, Missouri);  Congzhou Wang (St. Louis, Missouri);  Jeremiah J. Morrissey (St. Louis, Missouri);  Evan D. Kharasch (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Srikanth Singamaneni (St. Louis, Missouri);  Congzhou Wang (St. Louis, Missouri);  Jeremiah J. Morrissey (St. Louis, Missouri);  Evan D. Kharasch (St. Louis, Missouri)
ABSTRACT Methods and systems for preparing and preserving biological samples are disclosed herein. A method comprises contacting a preserving agent with a biological sample to form a mixture, wherein the preserving agent is selected from at least one of a metal-organic framework (MOF) encapsulant or a precursor forming a MOF encapsulant, and wherein the biological sample comprises at least one target analyte. A system comprises a preserving agent selected from at least one of a metal-organic framework (MOF) encapsulant or a precursor forming a MOF encapsulant; and a substrate configured to receive a drop cast mixture of the preserving agent and a biological sample, wherein the biological sample comprises at least one target analyte.
FILED Friday, April 20, 2018
APPL NO 16/606482
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0231 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/4044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857169 Yusuf et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) George Mason University (Fairfax, Virginia)
ASSIGNEE(S) George Mason Research Foundation, Inc. (Fairfax, Virginia)
INVENTOR(S) Sameen Yusuf (Fairfax, Virginia);  Marissa A. Howard (Fairfax, Virginia);  Sara Sharif (Fairfax, Virginia);  Kelsey Mitchell (Fairfax, Virginia);  Amanda Haymond Still (Fairfax, Virginia);  Ngoc Bao Vuong (Fairfax, Virginia);  Alessandra Luchini Kunkel (Fairfax, Virginia);  Lance A. Liotta (Fairfax, Virginia)
ABSTRACT A collapsible sample collection device with a novel, collapsible 3D capture open affinity net dispersed throughout the volume of the container, said net with tethered affinity moieties, is designed to address the need for low-cost, simple harvesting and concentration of diagnostic analytes that generally does not require any ancillary equipment. The collection device generally permits analytes of interest to be efficiently harvested from body fluid samples, in one step, concentrated, collapsed into a flat mailing size, and protected from degradation without the need for traditional cold chain technologies. The concentration factor will increase sensitivity by several orders of magnitude when coupled with any type of downstream analyte measurement, including point of care testing. The collection device, in various embodiments, obviates the need for handling transport or storage of the fluid portion of the body fluid sample (e.g. blood, urine, saliva, etc.) with a volumetric concentration factor of 5 to 100 fold. The collapsed collection device generally may be mailed to a laboratory for analysis via any chemical, immunological, electrical or other analytical methods.
FILED Tuesday, April 23, 2019
APPL NO 16/391942
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/150343 (20130101)
A61B 5/150755 (20130101)
A61B 10/007 (20130101) Original (OR) Class
A61B 10/0051 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857253 Karmarkar
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Parag Karmarkar (Baltimore, Maryland)
ABSTRACT The present disclosure provides a system with an innovative electrode designed as an RF/microwave antenna as well as methods to monitor/assess biological tissue and perform surgical procedures.
FILED Friday, January 08, 2021
APPL NO 17/145159
ART UNIT 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/05 (20130101)
A61B 5/0093 (20130101)
A61B 5/0507 (20130101)
A61B 5/0538 (20130101)
A61B 18/1492 (20130101)
A61B 18/1815 (20130101) Original (OR) Class
A61B 2017/00026 (20130101)
A61B 2017/00039 (20130101)
A61B 2017/00084 (20130101)
A61B 2017/00106 (20130101)
A61B 2018/00023 (20130101)
A61B 2018/00029 (20130101)
A61B 2018/183 (20130101)
A61B 2018/00351 (20130101)
A61B 2018/00577 (20130101)
A61B 2018/00636 (20130101)
A61B 2018/00702 (20130101)
A61B 2018/00773 (20130101)
A61B 2018/00785 (20130101)
A61B 2018/00791 (20130101)
A61B 2018/00827 (20130101)
A61B 2018/00875 (20130101)
A61B 2018/1435 (20130101)
A61B 2018/1823 (20130101)
A61B 2018/1838 (20130101)
A61B 2018/1846 (20130101)
A61B 2018/1853 (20130101)
A61B 2018/1861 (20130101)
A61B 2018/1892 (20130101)
A61B 2090/065 (20160201)
A61B 2218/002 (20130101)
A61B 2576/023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857288 Ghadimi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Sona Ghadimi (Charlottesville, Virginia);  Changyu Sun (Charlottesville, Virginia);  Xue Feng (Zion Crossroads, Virginia);  Craig H. Meyer (Charlottesville, Virginia);  Frederick H. Epstein (Charlottesville, Virginia)
ABSTRACT A method of cardiac strain analysis uses displacement encoded magnetic resonance image (MRI) data of a heart of the subject and includes generating a phase image for each frame of the displacement encoded MRI data. Phase images include potentially phase-wrapped measured phase values corresponding to pixels of the frame. A convolutional neural network CNN computes a wrapping label map for the phase image, and the wrapping label map includes a respective number of phase wrap cycles present at each pixel in the phase image. Computing an unwrapped phase image includes adding a respective phase correction to each of the potentially-wrapped measured phase values of the phase image, and the phase correction is based on the number of phase wrap cycles present at each pixel. Computing myocardial strain follows by using the unwrapped phase image for strain analysis of the subject.
FILED Wednesday, February 03, 2021
APPL NO 17/166604
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0044 (20130101) Original (OR) Class
A61B 5/055 (20130101)
A61B 5/02028 (20130101)
A61B 5/7267 (20130101)
A61B 5/7278 (20130101)
A61B 2576/023 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/56 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30048 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857289 Zhu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Quing Zhu (St. Louis, Missouri);  Mark Anastasio (St. Louis, Missouri);  Shihab Uddin (St. Louis, Missouri)
ABSTRACT A system and method for generating at least one optimized functional images of a lesion region of a subject is provided. The system includes a diffuse optical tomography (DOT) device, and a computing device. The DOT device is configured to acquire lesion functional data of an imaging volume including the lesion region of the breast and reference functional data from a corresponding imaging volume including healthy tissue within a contralateral breast. The computing device is programmed to generate at least one functional image of the breast by reconstructing the functional data at the plurality of regions including the lesion region and the surrounding adjacent background region. The functional images may be reconstructed by an optimization method regularized a preliminary estimate generated by applying a truncated pseudoinverse matrix of a weight matrix to the functional data. The optimized functional images relate to levels of hemoglobin at the voxels.
FILED Wednesday, October 24, 2018
APPL NO 16/649743
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0073 (20130101) Original (OR) Class
A61B 5/4312 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857306 Posse
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) UNM Rainforest Innovations (Albuquerque, New Mexico)
ASSIGNEE(S) UNM Rainforest Innovations (Albuquerque, New Mexico)
INVENTOR(S) Stefan Posse (Albuquerque, New Mexico)
ABSTRACT A method of obtaining multiple MRI contrasts of a subject comprising the steps of concurrently acquiring an MRSI and fMRI data in the same scan.
FILED Monday, April 26, 2021
APPL NO 17/240671
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/055 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/4806 (20130101)
G01R 33/4828 (20130101)

Image Data Processing or Generation, in General
G06T 2207/10088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857317 Valdes et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire);  UNIVERSITY HEALTH NETWORK (Toronto, Canada)
INVENTOR(S) Pablo Valdes (Phoenix, Arizona);  Frederic Leblond (Montreal, Canada);  Keith D. Paulsen (Hanover, New Hampshire);  Brian Campbell Wilson (Toronto, Canada);  David W. Roberts (Lyme, New Hampshire);  Michael Jermyn (Longueuil, Canada)
ABSTRACT An imaging system, such as a surgical microscope, laparoscope, or endoscope or integrated with these devices, includes an illuminator providing patterned white light and/or fluorescent stimulus light. The system receives and images light hyperspectrally, in embodiments using a hyperspectral imaging array, and/or using narrowband tunable filters for passing filtered received light to an imager. Embodiments may construct a 3-D surface model from stereo images, and will estimate optical properties of the target using images taken in patterned light or using other approximations obtained from white light exposures. Hyperspectral images taken under stimulus light are displayed as fluorescent images, and corrected for optical properties of tissue to provide quantitative maps of fluorophore concentration. Spectral information from hyperspectral images is processed to provide depth of fluorophore below the tissue surface. Quantitative images of fluorescence at depth are also prepared. The images are displayed to a surgeon for use in surgery.
FILED Thursday, October 06, 2022
APPL NO 17/961480
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/05 (20130101)
A61B 1/07 (20130101)
A61B 1/00009 (20130101)
A61B 1/042 (20130101)
A61B 1/043 (20130101)
A61B 1/000094 (20220201)
A61B 1/00165 (20130101)
A61B 1/00193 (20130101)
A61B 1/00194 (20220201)
A61B 1/0646 (20130101)
A61B 1/0669 (20130101)
A61B 1/0684 (20130101)
A61B 1/3132 (20130101)
A61B 5/055 (20130101)
A61B 5/0071 (20130101)
A61B 5/0077 (20130101)
A61B 5/1459 (20130101)
A61B 5/1495 (20130101)
A61B 5/7264 (20130101)
A61B 5/14546 (20130101)
A61B 5/14553 (20130101)
A61B 5/14556 (20130101) Original (OR) Class

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/0229 (20130101)
G01J 3/1256 (20130101)
G01J 3/2823 (20130101)
G01J 2003/1269 (20130101)
G01J 2003/2826 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857318 Hsiai et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Tzung K. Hsiai (Santa Monica, California);  Yu-Chong Tai (Pasadena, California);  Rene R. Sevag Packard (Los Angeles, California);  Yuan Luo (Pasadena, California);  Parinaz Abiri (Los Angeles, California);  Jianguo Ma (Shangdong Province, China PRC)
ABSTRACT The present invention provides devices for characterizing regions of tissue and methods for using the same. The devices are capable of locating, identifying, and characterizing tissue regions of interest in vivo. In one embodiment, the devices are ultrasound-guided. In one embodiment, the devices use characterize regions of tissue using electrical impedance spectroscopy (EIS) sensors. In one aspect, the devices are useful in predicting plaque rupture, such as by determining the level of oxidized low density lipoprotein (oxLDL) and macrophage/foam cells present in an atheroma. In one aspect, the devices are useful in identifying metabolically active atherosclerotic lesions that are angiographically invisible.
FILED Tuesday, May 09, 2017
APPL NO 16/099742
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/026 (20130101)
A61B 5/0205 (20130101)
A61B 5/0215 (20130101)
A61B 5/0537 (20130101)
A61B 5/0538 (20130101)
A61B 5/1473 (20130101) Original (OR) Class
A61B 5/02007 (20130101)
A61B 5/6853 (20130101)
A61B 5/7275 (20130101)
A61B 8/12 (20130101)
A61B 8/445 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 2025/1079 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/026 (20130101)
G01N 29/00 (20130101)
G01N 29/06 (20130101)
G01N 29/0654 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857333 Kayyali et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Hani Kayyali (Shaker Heights, Ohio);  Dan Bishop (Tallmadge, Ohio);  Brian M. Kolkowski (Leroy, Ohio)
ASSIGNEE(S) Cleveland Medical Devices Inc. (Cleveland, Ohio)
INVENTOR(S) Hani Kayyali (Shaker Heights, Ohio);  Dan Bishop (Tallmadge, Ohio);  Brian M. Kolkowski (Leroy, Ohio)
ABSTRACT The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to methods of sleep diagnosis and treatment. The sleep disorder treatment system of the present invention can use a diagnosis device to perform various forms of analysis to determine or diagnose a subject's sleeping disorder or symptoms of a subject's sleep disorder, and using this analysis or diagnosis can with or in some embodiments without human intervention treat the subject either physically or chemically to improve the sleeping disorder or the symptoms of the sleeping disorder. The diagnostic part of the system can use many different types of sensors and methods for diagnosing the severity of the symptoms of or the sleep disorder itself. The treatment part of the system can use a device to physically or chemically treat the subject's symptoms or sleep disorder itself.
FILED Wednesday, July 05, 2017
APPL NO 15/641715
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/02 (20130101)
A61B 5/08 (20130101)
A61B 5/4818 (20130101) Original (OR) Class
A61B 5/4836 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 16/00 (20130101)
A61M 16/0003 (20140204)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857352 Tonge et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Research Foundation for the State University of New York (Albany, New York)
ASSIGNEE(S) THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
INVENTOR(S) Peter Tonge (Setauket, New York);  Zhuo Zhang (Coram, New York);  Peter Smith-Jones (Port Jefferson, New York);  Li Liu (Stony Brook, New York);  Hui Wang (Woodside, New York)
ABSTRACT The present invention provides a composition comprising the compound having the structure:
or a salt of the compound; 4-amino-2-[19F]-fluorobenzoic acid or a salt of 4-amino-2-[19F]-fluorobenzoic acid; and at least one acceptable carrier.
FILED Wednesday, September 06, 2017
APPL NO 16/330679
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/037 (20130101) Original (OR) Class

Preparations for Medical, Dental, or Toilet Purposes
A61K 51/0402 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

General Methods of Organic Chemistry; Apparatus Therefor
C07B 59/001 (20130101)

Acyclic or Carbocyclic Compounds
C07C 227/12 (20130101)
C07C 229/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857509 Reshetnyak et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island);  Yale University (New Haven, Connecticut)
ASSIGNEE(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island);  Yale University (New Haven, Connecticut)
INVENTOR(S) Yana K. Reshetnyak (South Kingstown, Rhode Island);  Oleg A. Andreev (South Kingstown, Rhode Island);  Donald M. Engelman (New Haven, Connecticut)
ABSTRACT The present application relates to compositions comprising and methods of using a liposome comprising a pHLIP polypeptide, wherein a lipid bilayer of the liposome is substantially free of the pHLIP polypeptide.
FILED Tuesday, December 17, 2019
APPL NO 16/717577
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 9/1271 (20130101) Original (OR) Class
A61K 31/20 (20130101)
A61K 31/337 (20130101)
A61K 31/704 (20130101)
A61K 31/711 (20130101)
A61K 31/713 (20130101)
A61K 31/7105 (20130101)
A61K 47/6911 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857531 Thumbikat et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Praveen Thumbikat (Chicago, Illinois);  Anthony J. Schaeffer (Hinsdale, Illinois)
ABSTRACT Provided herein are compositions and methods for the treatment of conditions such as benign prostatic hyperplasia (BPH), Lower Urinary Tract Symptoms (LUTS), chronic prostatitis (CP) and/or chronic pelvic pain syndrome (CPPS). In particular, provided herein are combination therapies comprising a mast cell inhibitor and a histamine receptor antagonist.
FILED Thursday, August 05, 2021
APPL NO 17/395153
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/352 (20130101) Original (OR) Class
A61K 31/495 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 13/08 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857541 Gordon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Leslie B. Gordon (Foxboro, Massachusetts);  Mark W. Kieran (Newton, Massachusetts);  Monica E. Kleinman (Sharon, Massachusetts)
ASSIGNEE(S)
INVENTOR(S) Leslie B. Gordon (Foxboro, Massachusetts);  Mark W. Kieran (Newton, Massachusetts);  Monica E. Kleinman (Sharon, Massachusetts)
ABSTRACT Provided herein are combination therapies for the treatment of progeroid diseases and conditions, cellular aging, bone diseases, and cardiovascular diseases. The provided combination therapies target the aberrant farnesylation of the mutant lamin A protein progerin and increase progerin clearance.
FILED Tuesday, June 30, 2020
APPL NO 16/916145
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/20 (20130101)
A61K 9/0053 (20130101)
A61K 31/22 (20130101)
A61K 31/22 (20130101)
A61K 31/55 (20130101)
A61K 31/436 (20130101) Original (OR) Class
A61K 31/436 (20130101)
A61K 31/663 (20130101)
A61K 31/675 (20130101)
A61K 31/675 (20130101)
A61K 31/4545 (20130101)
A61K 31/4545 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857549 Aguilar
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Ruben Claudio Aguilar (West Lafayette, Indiana)
ABSTRACT A combination of active agents for the treatment of Lowe Syndrome (LS) comprising a RhoA inhibitor and a mTOR inhibitor; a pharmaceutical composition comprising the combination and a pharmaceutically acceptable carrier; a combination of pharmaceutical compositions in which one composition comprises a RhoA inhibitor and the other composition comprises a mTOR inhibitor; and a method of treating a patient for LS.
FILED Thursday, July 08, 2021
APPL NO 17/370676
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/436 (20130101)
A61K 31/505 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857550 Chen et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as Represented By the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Beibei Chen (Sewickley, Pennsylvania);  Rama K. Mallampalli (Sewickley, Pennsylvania)
ABSTRACT A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: wherein X is a divalent linking moiety; and R1-R10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R3 or R8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen.
FILED Thursday, November 19, 2020
APPL NO 16/953201
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/137 (20130101)
A61K 31/341 (20130101)
A61K 31/381 (20130101)
A61K 31/402 (20130101)
A61K 31/427 (20130101)
A61K 31/435 (20130101)
A61K 31/444 (20130101)
A61K 31/506 (20130101) Original (OR) Class
A61K 31/4155 (20130101)
A61K 31/4178 (20130101)
A61K 31/4418 (20130101)
A61K 31/5375 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)
A61P 11/06 (20180101)
A61P 19/00 (20180101)
A61P 25/00 (20180101)
A61P 35/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 211/01 (20130101)
C07C 211/53 (20130101)
C07C 229/38 (20130101)

Heterocyclic Compounds
C07D 207/06 (20130101)
C07D 211/14 (20130101)
C07D 213/06 (20130101)
C07D 213/36 (20130101)
C07D 213/38 (20130101)
C07D 231/12 (20130101)
C07D 233/61 (20130101)
C07D 233/64 (20130101)
C07D 239/26 (20130101)
C07D 265/30 (20130101)
C07D 277/28 (20130101)
C07D 295/135 (20130101)
C07D 401/12 (20130101)
C07D 403/12 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857551 Zuo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) Ting Therapeutics LLC (Omaha, Nebraska)
ASSIGNEE(S) Ting Therapeutics LLC (Omaha, Nebraska)
INVENTOR(S) Jian Zuo (Omaha, Nebraska);  Pezhman Salehi Dermanaki (Elkhorn, Nebraska)
ABSTRACT Acquired hearing loss due to chemotherapy or noise exposure is a major health problem, and cisplatin chemotherapy often causes permanent hearing loss in cancer patients. However, there are no FDA-approved drugs for the treatment or prevention of cisplatin- or noise-induced hearing loss. In one aspect, use of compounds as an active agent to treat a hearing impairment and to prevent a hearing impairment, and methods of treating and/or preventing hearing impairments or disorders using the compositions are disclosed. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Friday, July 09, 2021
APPL NO 17/371847
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 11/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/513 (20130101)
A61K 31/517 (20130101) Original (OR) Class
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857563 Pernis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) New York Society for the Relief of the Ruptured and Crippled, maintaining the Hospital for Special Surgery (New York, New York)
ASSIGNEE(S) NEW YORK SOCIETY FOR THE RELIEF OF THE RUPTURED AND CRIPPLED, MAINTAINING THE HOSPITAL FOR SPECIAL SURGERY (New York, New York)
INVENTOR(S) Alessandra Pernis (Mountain Lakes, New Jersey);  Michela Manni (New York, New York)
ABSTRACT This current invention provides methods and agents for preventing and treating autoimmune and lymphoproliferative disease by targeting pathogenic age-associated B cells as well as methods of detecting these pathogenic age-associated B cells as a method of diagnosing and predicting autoimmune disease and other lymphoproliferative and chronic inflammatory disorders. The current invention also provides targets for drug development and basic research for autoimmune diseases and other lymphoproliferative and chronic inflammatory disorders.
FILED Friday, August 27, 2021
APPL NO 17/459213
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 5/48 (20180101)
A61P 35/00 (20180101)

Peptides
C07K 16/3061 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/122 (20130101)
C12N 2310/141 (20130101)
C12N 2320/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857571 Sentman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Charles Sentman (Grantham, New Hampshire);  Michael Battles (Canaan, New Hampshire)
ABSTRACT Antigen binding fragments, chimeric antigen receptors, and bi-specific T-cell engagers having specificity for MICA and methods for using the same in the diagnosis and treatment of disorders associated with MICA and/or MICB expression are provided.
FILED Monday, August 17, 2020
APPL NO 16/994795
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class
A61K 47/6835 (20170801)
A61K 51/1045 (20130101)
A61K 51/1096 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2809 (20130101)
C07K 16/2833 (20130101)
C07K 16/2851 (20130101)
C07K 2317/31 (20130101)
C07K 2317/622 (20130101)
C07K 2319/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857598 Totary-Jain
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of South Florida (Tampa, Florida)
ASSIGNEE(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
INVENTOR(S) Hana Totary-Jain (Wesley Chapel, Florida)
ABSTRACT Described herein are cell-selective mRNA constructs that can contain a RNA of interest and one or more miRNA targets. The cell-selective mRNA constructs described herein can be used to express an RNA of interest to a cell in a cell-selective manner.
FILED Thursday, August 12, 2021
APPL NO 17/400984
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 31/7115 (20130101)
A61K 38/1709 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2310/113 (20130101)
C12N 2310/141 (20130101)
C12N 2330/10 (20130101)
C12N 2710/10343 (20130101)

Enzymes
C12Y 207/07048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857609 Troy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Carol M. Troy (Hastings-on-Hudson, New York);  Ying Y. Jean (New York, New York)
ABSTRACT The present disclosure relates to a method for treating diabetic macular edema (DME) and/or retinal vein occlusion (RVO) comprising administering to the retina of a patient in need thereof an effective amount of a caspase-9 signaling pathway inhibitor. The caspase-9 signaling pathway inhibitor may include a peptide caspase-9 inhibitor and/or may be conjugated to a cell-penetrating peptide. The present disclosure further includes pharmaceutical compositions including a caspase-9 signaling pathway inhibitor. The disclosure further relates to the use of such compositions in a method for treating DME and/or RVO.
FILED Tuesday, November 30, 2021
APPL NO 17/538924
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 38/55 (20130101) Original (OR) Class
A61K 47/64 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857618 Compans et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Emory University (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Richard Compans (Atlanta, Georgia);  Elena Vassilieva (Roswell, Georgia)
ABSTRACT This disclosure relates to boosting the immunogenicity of vaccines using an adjuvant combination comprising a saponin and an agonist of the intracellular stimulator of interferon genes pathway. In certain embodiments, the vaccine comprises an inactivated virus, attenuated virus, virus protein, virus like particle, or virosome. In certain embodiments, the human subject is of advanced age or elderly. In certain embodiments, the viral vaccine is an influenza vaccine.
FILED Friday, April 16, 2021
APPL NO 17/233333
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39 (20130101)
A61K 39/145 (20130101) Original (OR) Class
A61K 2039/55 (20130101)
A61K 2039/55555 (20130101)
A61K 2039/55561 (20130101)
A61K 2039/55577 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/16 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857631 Jeffries et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Nursing Research (NINR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Eric M. Jeffries (West New York, New Jersey);  Yadong Wang (Bradford Woods, Pennsylvania);  Daniel Long (Pittsburgh, Pennsylvania);  Noah R. Johnson (Pittsburgh, Pennsylvania)
ABSTRACT Compositions are provided herein comprising a coacervate of a polycationic polymer, a polyanionic polymer, and platelet-rich plasma and/or serum, or a fraction or concentrate thereof. The composition is useful in wound healing. Compositions also are provided that comprise a hydrogel comprising TIMP-3; and a complex of a polycationic polymer, a polyanionic polymer, FGF-2 and SDF-1α embedded in the hydrogel, which is useful in treating a myocardial infarction.
FILED Tuesday, November 23, 2021
APPL NO 17/533958
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0019 (20130101)
A61K 35/16 (20130101)
A61K 35/19 (20130101)
A61K 38/18 (20130101)
A61K 38/177 (20130101)
A61K 38/195 (20130101)
A61K 38/1825 (20130101)
A61K 47/34 (20130101)
A61K 47/36 (20130101) Original (OR) Class
A61K 47/42 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/40 (20130101)
A61L 15/44 (20130101)
A61L 15/225 (20130101)
A61L 15/225 (20130101)
A61L 27/18 (20130101)
A61L 27/20 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 27/225 (20130101)
A61L 27/3616 (20130101)
A61L 31/16 (20130101)
A61L 31/041 (20130101)
A61L 31/042 (20130101)
A61L 31/046 (20130101)
A61L 31/145 (20130101)
A61L 2300/25 (20130101)
A61L 2300/252 (20130101)
A61L 2300/414 (20130101)
A61L 2300/418 (20130101)
A61L 2400/04 (20130101)
A61L 2430/20 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Compositions of Macromolecular Compounds
C08L 5/10 (20130101)
C08L 5/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857633 Herrmann et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) City of Hope (Duarte, California)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Andreas Herrmann (Del Mar, California);  Hua Yu (Glendora, California)
ABSTRACT Provided herein are, inter alia, nucleic acid conjugates including a non-cell penetrating ribonucleic acid compound attached at its 3′ end to a phosphorothioate polymer. Attachment of the phosphorothioate polymer to the non-cell penetrating ribonucleic acid conveys stability to and allows for efficient intracellular delivery of the non-cell penetrating ribonucleic acid. The nucleic acid conjugates provided herein including embodiments thereof are useful, inter alia, for the treatment of cancer, inflammatory disease, and pain.
FILED Tuesday, March 30, 2021
APPL NO 17/217989
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/548 (20170801)
A61K 47/549 (20170801) Original (OR) Class
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/141 (20130101)
C12N 2320/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857634 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Song Li (Wexford, Pennsylvania);  Jingjing Sun (Pittsburgh, Pennsylvania);  Yichao Chen (Pittsburgh, Pennsylvania);  Yixian Huang (Pittsburgh, Pennsylvania);  Yanhua Liu (Pittsburgh, Pennsylvania);  Binfeng Lu (Pittsburgh, Pennsylvania)
ABSTRACT A formulation includes a plurality of polymers including a hydrophobic polymer backbone (for example, formed via radical polymerization), a first plurality of pendant groups attached to the hydrophobic polymer backbone and including at least one cationic group, and a second plurality of pendant groups attached to the hydrophobic polymer backbone and including at least one hydrophilic polymer, a first therapeutic compound, and a second therapeutic compound, wherein the second therapeutic compound is different from the first therapeutic compound and includes a nucleic acid.
FILED Saturday, April 20, 2019
APPL NO 17/049152
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1075 (20130101)
A61K 31/65 (20130101)
A61K 47/58 (20170801) Original (OR) Class
A61K 47/549 (20170801)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/351 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857648 Zeng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Dexing Zeng (Portland, Oregon);  Lingyi Sun (Pittsburgh, Pennsylvania);  Yongkang Gai (Pittsburgh, Pennsylvania)
ABSTRACT The present invention provides a multivalent compound for targeted molecular imaging and/or targeted drug delivery, wherein two components or targeting molecules each interacts with one or more biomarkers on a cell. The present invention further provides a multifunctional chelator to combine the targeting molecules. The present invention also provides an in vitro high-throughput screening assay to determine the length of the spacer molecules. The present invention also relates to compounds/probes, kits and methods for use in targeted molecular imaging and/or targeted drug delivery.
FILED Friday, November 02, 2018
APPL NO 16/179817
ART UNIT RD00 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/51 (20130101)
A61K 47/6893 (20170801)
A61K 51/082 (20130101) Original (OR) Class
A61K 51/1027 (20130101)

Heterocyclic Compounds
C07D 255/02 (20130101)
C07D 257/02 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 7/64 (20130101)
C07K 16/30 (20130101)
C07K 2319/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/60 (20130101)
G01N 33/5008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857697 Spence et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Jason Spence (Ann Arbor, Michigan);  Alyssa Miller (Ann Arbor, Michigan)
ABSTRACT The invention disclosed herein generally relates to methods and systems for growing, expanding and/or obtaining 3-dimensional lung-like epithelium comprising cells having SOX9 protein activity and SOX2+ protein activity. In particular, the invention disclosed herein relates to methods and systems for growing human cells having SOX9 protein activity and SOX2+ protein activity in vitro, and for promoting pluripotent stem cell derived ventral-anterior foregut spheroid tissue into 3-dimensional lung-like epithelium comprising cells having SOX9 protein activity and SOX2+ protein activity.
FILED Thursday, May 31, 2018
APPL NO 15/994749
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/42 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/3804 (20130101)
A61L 27/3813 (20130101)
A61L 27/3834 (20130101)
A61L 27/3839 (20130101)
A61L 27/3869 (20130101)
A61L 27/3895 (20130101) Original (OR) Class
A61L 2430/22 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0018 (20130101)
C12N 5/0062 (20130101)
C12N 5/0606 (20130101)
C12N 5/0607 (20130101)
C12N 5/0688 (20130101)
C12N 5/0689 (20130101)
C12N 2501/113 (20130101)
C12N 2501/115 (20130101)
C12N 2501/117 (20130101)
C12N 2501/119 (20130101)
C12N 2501/155 (20130101)
C12N 2501/385 (20130101)
C12N 2501/415 (20130101)
C12N 2501/999 (20130101)
C12N 2506/02 (20130101)
C12N 2506/03 (20130101)
C12N 2506/27 (20130101)
C12N 2506/45 (20130101)
C12N 2513/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857809 Chalasani et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Salk Institute for Biological Studies (La Jolla, California)
ASSIGNEE(S) Salk Institute for Biological Studies (La Jolla, California)
INVENTOR(S) Sreekanth H. Chalasani (La Jolla, California);  Stuart Ibsen (La Jolla, California)
ABSTRACT The invention provides compositions featuring TRP-4 polypeptides and polynucleotides, methods for expressing such polypeptides and polynucleotides in a cell type of interest, and methods for inducing the activation of the TRP-4 polypeptide in neurons and other cell types using ultrasound.
FILED Wednesday, September 23, 2020
APPL NO 17/029143
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 41/0033 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/00 (20130101) Original (OR) Class
A61N 2007/0026 (20130101)

Peptides
C07K 14/705 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 13/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 29/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857813 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Aeronautics and Space Administration (NASA)
National Space Biomedical Research Institute (NSBRI)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Yak-Nam Wang (Seattle, Washington);  Michael R. Bailey (Seattle, Washington);  Tatiana D. Khokhlova (Seattle, Washington);  Wayne Kreider (Seattle, Washington);  Adam D. Maxwell (Seattle, Washington);  George R. Schade (Seattle, Washington);  Vera A. Khokhlova (Seattle, Washington)
ABSTRACT High intensity focused ultrasound systems for treating tissue are disclosed herein. A system of treating tissue in a patient in accordance with an embodiment of the present technology can include, for example, an ultrasound source having a focal region and configured to deliver high intensity focused ultrasound energy to a target site in tissue of the patient. The system can further include a controller operably coupled to the ultrasound source. The controller comprises a pulsing protocol for delivering the high intensity focused ultrasound energy with the ultrasound source to the target site. The controller is configured to cause the ultrasound source to pulse high intensity focused ultrasound waves to lyse cells in a volume of the tissue of the subject while preserving an extracellular matrix in the volume of the tissue exposed to the high intensity focused ultrasound waves.
FILED Monday, July 13, 2020
APPL NO 16/927860
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/02 (20130101) Original (OR) Class
A61N 2007/0004 (20130101)
A61N 2007/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857837 Wechsler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute on Drug Abuse (NIDA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Emily Wechsler (Dallas, Texas);  Ryan Halter (Lyme, New Hampshire);  John A. Batsis (Hanover, New Hampshire)
ABSTRACT Devices and methods are disclosed for remote clinical monitoring performance of exercises using an instrumented resistance device (100). An example device (100) includes a resistance band (120) having a first end (122) and a second end (124). A first handle (130) connected to the first end (122) and a second handle (140) connected to the second end (124) of the resistance band (120). The device (100) further includes a force sensing assembly (150) positioned between the first handle (130) and the first end (122). The force sensing assembly (150) includes a force sensor (156) connected to the resistance band (120), a microcontroller (182) connected to the force sensor (156) to receive a set of load force measurements from the force sensor (156), and a communication module (184) connected to the microcontroller (182) to transmit the set of load force measurements to a local data receiving device (170).
FILED Friday, May 17, 2019
APPL NO 17/055412
ART UNIT 3784 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 21/00043 (20130101)
A63B 21/0552 (20130101)
A63B 21/4035 (20151001)
A63B 24/0062 (20130101) Original (OR) Class
A63B 2220/17 (20130101)
A63B 2220/51 (20130101)
A63B 2220/62 (20130101)
A63B 2220/833 (20130101)
A63B 2225/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858877 Camacho et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
NSF Graduate Research Fellowship Program (GRFP)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Carlos Jaime Camacho (Pittsburgh, Pennsylvania);  Robin E. C. Lee (Pittsburgh, Pennsylvania)
ABSTRACT Provided herein are small molecules that specifically inhibit TNF-induced nuclear factor kB (NF-kB) inflammation pathway. Also provided are methods of screening compounds to identify molecules that specifically inhibit a TNF-induced NF-kB inflammation pathway, methods of inhibiting TNF-induced NF-kB inflammation pathway, and methods of preventing formation of mature TNFR1 complex.
FILED Monday, February 24, 2020
APPL NO 16/799130
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)

Acyclic or Carbocyclic Compounds
C07C 233/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858879 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) City of Hope (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Xiaochun Yu (Glendora, California);  Shih-Hsun Chen (Duarte, California);  Yate-Ching Yuan (Duarte, California);  Hongzhi Li (Duarte, California);  David Horne (Altadena, California)
ABSTRACT Provided herein are, inter alia, compounds inhibiting poly(ADP-ribose) Glycohydrolase (PARG) in a cancer cell and methods of treating cancer using compounds of the invention.
FILED Friday, June 22, 2018
APPL NO 16/625511
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 251/86 (20130101) Original (OR) Class
C07C 311/17 (20130101)
C07C 311/29 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858880 Ojima et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
ASSIGNEE(S) THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York)
INVENTOR(S) Iwao Ojima (Port Jefferson, New York);  Maurizio Del Poeta (Mount Sinai, New York);  Cristina Lazzarini (East Setauket, New York);  Krupanandan Hanarahalli (Setauket, New York);  Yi Sun (Mount Sinai, New York)
ABSTRACT The present invention provides a compound having the structure:
and use of the compound for inhibiting the growth of or killing
FILED Friday, June 10, 2022
APPL NO 17/837548
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 37/28 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/195 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/10 (20180101)

Acyclic or Carbocyclic Compounds
C07C 251/86 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 213/86 (20130101)
C07D 215/54 (20130101)
C07D 239/30 (20130101)
C07D 307/68 (20130101)
C07D 309/08 (20130101)
C07D 333/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858888 Bazan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana);  University of Southern California (Los Angeles, California)
ASSIGNEE(S) BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana);  UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Nicolas G. Bazan (New Orleans, Louisiana);  Nicos A. Petasis (Los Angeles, California)
ABSTRACT This disclosure provides compounds, pharmaceutical compositions, and methods of use for the prevention and treatment of inflammatory diseases or degenerative diseases including neurodegenerative diseases. Embodiments of the present disclosure provide compounds related to very long chain polyunsaturated fatty acids, pharmaceutical compositions containing the provided compounds, and methods of treating a subject with a condition or disease using provided compounds or pharmaceutical compositions.
FILED Monday, April 27, 2020
APPL NO 16/859791
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/202 (20130101)
A61K 31/232 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
A61P 29/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 57/03 (20130101) Original (OR) Class
C07C 59/42 (20130101)
C07C 69/587 (20130101)
C07C 69/732 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/10 (20130101)
C07F 9/106 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858897 Hatcher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) John Hatcher (Marlborough, Massachusetts);  Nathanael S. Gray (Boston, Massachusetts);  Hwangeun Choi (Seoul, South Korea);  Pasi Janne (Needham, Massachusetts);  Tinghu Zhang (Brookline, Massachusetts)
ABSTRACT The application relates to a compound of Formula (I):
which modulates the activity of ALK or SRPK, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which ALK or SRPK plays a role.
FILED Tuesday, June 15, 2021
APPL NO 17/348394
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 209/80 (20130101) Original (OR) Class
C07D 401/04 (20130101)
C07D 401/14 (20130101)
C07D 403/04 (20130101)
C07D 405/04 (20130101)
C07D 405/14 (20130101)
C07D 409/04 (20130101)
C07D 413/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/12 (20130101)
C12N 9/96 (20130101)

Enzymes
C12Y 207/11001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858908 Hamrick et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Augusta University Research Institute, Inc. (Augusta, Georgia)
ASSIGNEE(S) Augusta University Research Institute, Inc. (Augusta, Georgia)
INVENTOR(S) Mark Hamrick (Evans, Georgia);  Carlos Isales (Augusta, Georgia);  Iryna Lebedyeva (Augusta, Georgia)
ABSTRACT Provided herein are compounds that inhibit IDO1 and methods of use thereof. Also provided are pharmaceutical compositions and medicaments that include the compounds described herein as well as methods of treating sarcopenia or age-related muscle loss.
FILED Wednesday, January 19, 2022
APPL NO 17/579505
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 69/66 (20130101)

Heterocyclic Compounds
C07D 311/06 (20130101)
C07D 317/60 (20130101) Original (OR) Class
C07D 405/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858917 Spiegel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) David Spiegel (New Haven, Connecticut);  Christopher Parker (Medina, Ohio)
ABSTRACT The present invention is directed to new bifunctional compounds and methods for treating HIV infections. The bifunctional small molecules, generally referred to as ARM-HI's, function through orthogonal pathways, by inhibiting the gp120-CD4 interaction, and by recruiting anti-DNP antibodies to gp120-expressing cells, thereby preventing cell infection and spread of HIV. It has been shown that ARM-HI's bind to gp120 and gp-120 expressing cells competitively with CD4, thereby decreasing viral infectivity as shown by an MT-2 cell assay, the binding leading to formation of a ternary complex by recruiting anti-DNP antibodies to bind thereto, the antibodies present in the ternary complex promoting the complement-dependent destruction of the gp120-expressing cells. Compounds and methods are described herein.
FILED Thursday, September 09, 2021
APPL NO 17/470393
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0014 (20130101)
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 405/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858925 Winkler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Alyssa Winkler (Ann Arbor, Michigan);  Brian Linhares (Ann Arbor, Michigan);  Dymytrii Listunov (Ann Arbor, Michigan);  Jolanta Grembecka (Ann Arbor, Michigan);  Tomasz Cierpicki (Ann Arbor, Michigan);  EunGi Kim (Ann Arbor, Michigan)
ABSTRACT Provided herein are small molecules that bind to GAS41 and inhibit GAS41 activity, and methods of use thereof for the treatment of cancer.
FILED Wednesday, January 27, 2021
APPL NO 17/159916
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/55 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 409/06 (20130101)
C07D 409/14 (20130101)
C07D 417/14 (20130101) Original (OR) Class
C07D 487/10 (20130101)
C07D 495/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858939 Jefson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Alkermes, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Alkermes, Inc. (Waltham, Massachusetts)
INVENTOR(S) Martin R. Jefson (Stonington, Connecticut);  John A. Lowe, III (Stonington, Connecticut);  Fabian Dey (Basel, Switzerland);  Andreas Bergmann (Gauting, Germany);  Andreas Schoop (Grafrath, Germany);  Nathan Oliver Fuller (Arlington, Massachusetts)
ABSTRACT This invention provides compounds that are inhibitors of HDAC2. The compounds (e.g., compounds according to Formula I, II or any of Compounds 100-128 or any of those in Tables 2 or 3) accordingly are useful for treating, alleviating, or preventing a condition in a subject such as a neurological disorder, memory or cognitive function disorder or impairment, extinction learning disorder, fungal disease or infection, inflammatory disease, hematological disease, or neoplastic disease, or for improving memory or treating, alleviating, or preventing memory loss or impairment.
FILED Monday, December 28, 2020
APPL NO 17/134875
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/13 (20130101)
A61K 31/13 (20130101)
A61K 31/27 (20130101)
A61K 31/27 (20130101)
A61K 31/40 (20130101)
A61K 31/40 (20130101)
A61K 31/44 (20130101)
A61K 31/44 (20130101)
A61K 31/50 (20130101)
A61K 31/50 (20130101)
A61K 31/55 (20130101)
A61K 31/55 (20130101)
A61K 31/167 (20130101)
A61K 31/167 (20130101)
A61K 31/351 (20130101)
A61K 31/351 (20130101)
A61K 31/415 (20130101)
A61K 31/415 (20130101)
A61K 31/421 (20130101)
A61K 31/421 (20130101)
A61K 31/426 (20130101)
A61K 31/426 (20130101)
A61K 31/427 (20130101)
A61K 31/427 (20130101)
A61K 31/435 (20130101)
A61K 31/435 (20130101)
A61K 31/437 (20130101)
A61K 31/437 (20130101)
A61K 31/444 (20130101)
A61K 31/444 (20130101)
A61K 31/445 (20130101)
A61K 31/445 (20130101)
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/505 (20130101)
A61K 31/505 (20130101)
A61K 31/506 (20130101)
A61K 31/506 (20130101)
A61K 31/4155 (20130101)
A61K 31/4155 (20130101)
A61K 31/4192 (20130101)
A61K 31/4192 (20130101)
A61K 31/4433 (20130101)
A61K 31/4433 (20130101)
A61K 31/4439 (20130101)
A61K 31/4439 (20130101)
A61K 31/4965 (20130101)
A61K 31/4965 (20130101)
A61K 31/4985 (20130101)
A61K 31/4985 (20130101)
A61K 31/5377 (20130101)
A61K 31/5377 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 207/06 (20130101)
C07D 309/14 (20130101)
C07D 401/12 (20130101)
C07D 401/14 (20130101)
C07D 403/12 (20130101)
C07D 405/12 (20130101)
C07D 409/12 (20130101)
C07D 413/14 (20130101)
C07D 417/12 (20130101)
C07D 417/14 (20130101)
C07D 471/10 (20130101)
C07D 487/04 (20130101) Original (OR) Class
C07D 487/10 (20130101)
C07D 491/107 (20130101)
C07D 513/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858956 Moukha-Chafiq et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Southern Research Institute (Birmingham, Alabama);  Oregon Health and Science University (Portland, Oregon);  Washington University in St. Louis (St. Louis, Missouri);  Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Southern Research Institute (Birmingham, Alabama);  Oregon Health and Science University (Portland, Oregon);  Washington University in St. Louis (St. Louis, Louisiana);  Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Omar Moukha-Chafiq (Hoover, Alabama);  Ashish Kumar Pathak (Birmingham, Alabama);  Shuklendu D. Karyakarte (Birmingham, Alabama);  Larry D. Bratton (Birmingham, Alabama);  Corinne E. Augelli-Szafran (Homewood, Alabama);  Michael Diamond (St. Louis, Missouri);  Pei Yong Shi (Galveston, Texas);  Alec Jay Hirsch (Portland, Oregon);  Jessica Lee Smith (Beaverton, Oregon);  Daniel Streblow (Banks, Oregon);  Nicole Haese (Beaverton, Oregon);  Baoling Ying (Ballwin, Missouri)
ABSTRACT The present disclosure is concerned with 6-aza-nucleoside prodrugs that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, yellow fever virus, tick-borne encephalitis virus, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), Middle East Respiratory Syndromes (MERS), Severe Acute Respiratory Syndrome (SARS), and coronavirus disease 2019 (COVID-19), using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Friday, December 17, 2021
APPL NO 17/554979
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
A61P 31/16 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858966 Niederweis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) THE UAB RESEARCH FOUNDATION (Birmingham, Alabama)
ASSIGNEE(S) THE UAB RESEARCH FOUNDATION (Birmingham, Alabama)
INVENTOR(S) Michael Niederweis (Homewood, Alabama);  Mikhail Pavlenok (Birmingham, Alabama)
ABSTRACT Provided herein are mutant single-chain Mycobacterium smegmatis porin (Msp) and uses thereof.
FILED Thursday, February 17, 2022
APPL NO 17/674140
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/35 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/44743 (20130101)
G01N 27/44756 (20130101)
G01N 33/48721 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858968 Truong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) New York University (New York, New York)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) David M. Truong (New York, New York);  Jef D. Boeke (New York, New York)
ABSTRACT Yeast having modified chromosomes are provided. The chromosomes are modified such that at least one of yeast histones H3, H4, H2A or H2B are fully or partially replaced by their human histone counterparts H3, H4, H2A or H2B, respectively. Histone amino acid substitutions are included. Cell fusions with the yeast having the modified chromosomes and non-yeast cells are provided. Methods for screening test agents using the yeast are also provided. Yeast with a mutated yeast DAD1 gene, the mutated DAD1 gene encoding an E50D mutation in yeast DAD1 protein, are provided, and provide a useful genetic background for making the yeast with partially or fully replaced histone(s).
FILED Tuesday, July 06, 2021
APPL NO 17/368216
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/47 (20130101)
C07K 14/395 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858969 Gradinaru et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Viviana Gradinaru (La Canada Flintridge, California);  Claire N. Bedbrook (Pasadena, California);  Frances H. Arnold (La Canada Flintridge, California);  Kevin K. Yang (Cambridge, Massachusetts)
ABSTRACT Disclosed herein are engineered light-sensitive proteins, for example channelrhodopsins and variants thereof. Also disclosed are compositions for expressing the light-sensitive proteins in cells, tissues, organs and subjects, and methods for using the light-sensitive proteins to, for example, enable minimally-invasive neuronal circuit interrogation in living organism, and treat neuronal and ocular disorders.
FILED Tuesday, September 17, 2019
APPL NO 16/573321
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/062 (20130101)
A61N 5/0622 (20130101)
A61N 2005/063 (20130101)
A61N 2005/0647 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 27/02 (20180101)

Peptides
C07K 14/405 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2750/14132 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858976 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Tong Zhang (Beijing, China PRC);  Charles L Sentman (West Lebanon, New Hampshire)
ABSTRACT The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provided.
FILED Wednesday, June 15, 2022
APPL NO 17/841117
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 38/10 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 14/705 (20130101) Original (OR) Class
C07K 14/715 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858998 Dimitroff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Charles J. Dimitroff (Coral Gables, Florida);  Asmi Chakraborty (Boston, Massachusetts)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Charles J. Dimitroff (Coral Gables, Florida);  Asmi Chakraborty (Boston, Massachusetts)
ABSTRACT The present invention provides methods for diagnosis, prognosis, prevention and/or treatment of cancers such as melanomas. The subject invention provides biomarkers and methods for assessing the severity of a cancer/tumor and for monitoring the progressing of a cancer/tumor. The subject invention also provides therapeutic targets in cancer for developing anti-cancer therapies.
FILED Wednesday, January 25, 2023
APPL NO 18/101285
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2851 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859015 Scheinberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) David A. Scheinberg (New York, New York);  Tao Dao (New York, New York)
ABSTRACT This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a WT1-expressing cancer, comprising heteroclitic peptides derived from the WT-1 protein.
FILED Monday, August 31, 2020
APPL NO 17/007415
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/08 (20130101)
A61K 38/10 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 7/06 (20130101) Original (OR) Class
C07K 7/08 (20130101)
C07K 14/4748 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859019 Pei
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Dehua Pei (Columbus, Ohio)
ABSTRACT Anticachexin C1 inhibits the TNFα-TNFα receptor interaction. In this work, analogs of anticachexin C1 are disclosed. The resulting bicyclic peptides inhibit TNFα TNFα-induced cell death, NF-κB activation, and c-Jun N-terminal kinase (JNK) signaling in cultured mammalian cells. Methods of using the bicyclic peptide anticachexin C1 analogs to treat cancer, inflammatory disorders and immune disorders are also described.
FILED Tuesday, December 29, 2020
APPL NO 17/136578
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 29/00 (20180101)

Peptides
C07K 7/56 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859020 Moskal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Joseph R. Moskal (Evanston, Illinois);  Jeffrey S. Burgdorf (Evanston, Illinois)
ABSTRACT Described herein are isolated peptides, compositions comprising the same, and methods of using such peptides or compositions in the treatment of depression, central nervous system disorders, and neurodevelopmental disorders.
FILED Thursday, January 27, 2022
APPL NO 17/586185
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/14 (20180101)
A61P 25/22 (20180101)
A61P 25/24 (20180101)

Peptides
C07K 7/08 (20130101)
C07K 7/64 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859177 Lapotko et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) WILLIAM MARSH RICE UNIVERSITY (Houston, Texas)
ASSIGNEE(S) WILLIAM MARSH RICE UNIVERSITY (Houston, Texas)
INVENTOR(S) Dmitri Lapotko (Pearland, Texas);  Katsiaryna Hleb (Houston, Texas);  Janet Braam (Bellaire, Texas);  John S. Olson (Houston, Texas)
ABSTRACT Methods, systems, and apparatuses for employing nanobubbles for theranostic purposes are provided. In one embodiment, a method comprising introducing a photothermal nanobubble into a malaria-infected red blood cell is provided.
FILED Friday, July 26, 2019
APPL NO 16/523398
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0095 (20130101)
A61B 5/1455 (20130101)
A61B 5/14546 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/067 (20210801)
A61N 5/0624 (20130101)
A61N 5/0625 (20130101)
A61N 2005/0627 (20130101)
A61N 2005/0662 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 13/00 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/49 (20130101)
G01N 21/636 (20130101)
G01N 21/6458 (20130101)
G01N 2021/6439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859202 Lyons et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) University of Maryland, Baltimore (Baltimore, Maryland)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S) James Lyons (York, Pennsylvania);  Christopher Ward (Baltimore, Maryland);  Joseph Stains (Laurel, Maryland)
ABSTRACT The present invention relates to a fluid flow device. The device includes an elongate body having a proximal end, a distal end, and a length therebetween, at least one source fluid inflow port, at least one waste fluid outflow port, at least one well inlet port positioned at the distal end of the elongate body, at least one well outlet port positioned at the distal end of the elongate body, at least one conduit connecting the at least one source fluid inflow port to the at least one well inlet port, and at least one conduit connecting the at least one waste fluid outflow port to the at least one well outlet port.
FILED Thursday, January 21, 2021
APPL NO 17/154239
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/50853 (20130101)
B01L 2200/026 (20130101)
B01L 2300/046 (20130101)
B01L 2300/0829 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/12 (20130101)
C12M 35/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/00 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54366 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859208 Waller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Emory University (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Edmund Waller (Atlanta, Georgia);  Anna Morris (Atlanta, Georgia);  Christopher Petersen (Atlanta, Georgia);  Jian-Ming Li (Atlanta, Georgia);  Reema Panjwani (Bayside, New York);  Jingxia Li (Decatur, Georgia)
ABSTRACT This disclosure relates to compositions and methods of reversing senescence in T cells by interrupting vasoactive intestinal peptide (VIP) signaling and/or inhibiting phosphatidylinositol-3-kinase (PI3 kinase) inhibitor signaling and uses in managing cancer and chronic viral infections. In certain embodiments, the disclosure contemplates methods of reversing T cell senescence by mixing T cell in vitro with an agent that prevents VIP from interacting with VIP receptors and/or a PI3 Kinase inhibitor. In certain embodiments, the disclosure contemplates the expansion of senescent T cells by mixing with a PI3 kinase inhibitor, an agent that block VIP and VIP receptor signaling, a VIP degrading enzyme, and combinations thereof.
FILED Wednesday, April 05, 2017
APPL NO 16/092068
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 35/28 (20130101)
A61K 38/22 (20130101)
A61K 38/54 (20130101)
A61K 38/208 (20130101)
A61K 38/482 (20130101)
A61K 38/4886 (20130101)
A61K 39/39 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/00 (20180101)
A61P 35/00 (20180101)

Peptides
C07K 16/28 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 5/0638 (20130101) Original (OR) Class
C12N 2501/05 (20130101)
C12N 2501/515 (20130101)

Enzymes
C12Y 304/21039 (20130101)
C12Y 304/24011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859210 D'Lima et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) Scripps Health (San Diego, California)
ASSIGNEE(S) SCRIPPS HEALTH (San Diego, California)
INVENTOR(S) Darryl D. D'Lima (San Diego, California);  Tsaiwei Olee (San Diego, California);  Clifford W. Colwell (La Jolla, California)
ABSTRACT Disclosed herein are methods of producing chondrocytes from pluripotent stem cells. The invention further provides methods of regenerating cartilaginous tissue.
FILED Friday, June 05, 2020
APPL NO 16/894738
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/32 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0655 (20130101) Original (OR) Class
C12N 2501/15 (20130101)
C12N 2506/02 (20130101)
C12N 2533/54 (20130101)
C12N 2533/90 (20130101)
C12N 2537/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859220 Joung et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) J. Keith Joung (Winchester, Massachusetts);  Benjamin Kleinstiver (Boston, Massachusetts)
ABSTRACT Engineered CRISPR-Cas9 nucleases with altered and improved PAM specificities and their use in genomic engineering, epigenomic engineering, and genome targeting.
FILED Monday, November 22, 2021
APPL NO 17/456092
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 2227/40 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 2319/71 (20130101)
C07K 2319/80 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class
C12N 15/63 (20130101)
C12N 15/90 (20130101)
C12N 15/102 (20130101)
C12N 15/111 (20130101)
C12N 2310/20 (20170501)
C12N 2800/22 (20130101)
C12N 2800/80 (20130101)

Enzymes
C12Y 301/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859225 Smolke et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Complementary and Integrative Health (NCCIH)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Christina D. Smolke (Menlo Park, California);  Stephanie Galanie (Palo Alto, California);  Isis Trenchard (Redwood City, California);  Catherine Thodey (Mountain View, California);  Yanran Li (Mountain View, California)
ABSTRACT A method of epimerizing an (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid is provided. The method comprises contacting the (S)-1-benzylisoquinoline alkaloid with at least one enzyme. Contacting the (S)-1-benzylisoquinoline alkaloid with the at least one enzyme converts the (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid.
FILED Monday, May 09, 2016
APPL NO 15/567358
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0006 (20130101)
C12N 9/0071 (20130101)
C12N 15/52 (20130101)
C12N 15/62 (20130101)
C12N 2800/22 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 17/12 (20130101) Original (OR) Class
C12P 41/002 (20130101)

Enzymes
C12Y 101/01247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859242 Ly et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Danith H. Ly (Pittsburgh, Pennsylvania);  Wei-Che Hsieh (New Taipei, Taiwan);  Raman Bahal (Glastonbury, Connecticut)
ABSTRACT Described herein are genetic recognition reagents comprising terminal aromatic moieties that bind specifically to a template nucleic acid and concatenate. Also provided are methods of using the genetic recognition reagents, e.g., to treat or diagnose a repeat expansion disorder, such as DMI.
FILED Friday, December 21, 2018
APPL NO 16/955593
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)
C07H 21/04 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859250 Rothenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio)
ASSIGNEE(S) CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio)
INVENTOR(S) Marc E. Rothenberg (Cincinnati, Ohio);  Tetsuo Shoda (Cincinnati, Ohio);  Ting Wen (Cincinnati, Ohio)
ABSTRACT The present invention relates to methods for identifying an EoE endotype of a patient and treating the patient with one or more therapies targeted to the patient's disease endotype; and related methods for stratifying patients for clinical trials.
FILED Thursday, February 21, 2019
APPL NO 16/281750
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859972 Lipson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Michal Lipson (New York, New York);  Xingchen Ji (New York, New York);  Alexander Klenner (New York, New York);  Xinwen Yao (Baltimore, Maryland);  Yu Gan (Harriston, New Jersey);  Alexander L. Gaeta (New York, New York);  Christine P Hendon (Bronx, New York)
ABSTRACT A method of providing optical coherence tomography (OCT) imaging may comprise using an on-chip frequency comb source interfaced with an OCT system by a circulator as an imaging source and reconstructing OCT images from resulting spectral data from target tissue illuminated by the imaging source.
FILED Tuesday, July 06, 2021
APPL NO 17/367884
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02008 (20130101) Original (OR) Class
G01B 9/02091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860118 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) XiuJun Li (El Paso, Texas);  Wan Zhou (El Paso, Texas)
ABSTRACT A biosensing system configured to detect a target DNA and methods of detecting a target DNS are presented. The biosensing system comprises a biosensor comprising a suspension of a hybridization buffer containing dispersed gold nanoparticles, sodium chloride, and single-stranded DNA probes configured to undergo DNA hybridization with the target DNA.
FILED Friday, December 04, 2020
APPL NO 17/112841
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 35/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3276 (20130101)
G01N 27/3277 (20130101)
G01N 27/3278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860161 Mozaffarian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Seattle Children's Hospital (Seattle, Washington)
ASSIGNEE(S) Seattle Children's Hospital (Seattle, Washington)
INVENTOR(S) Neelufar Mozaffarian (Mercer Island, Washington);  Anne M. Stevens (Seattle, Washington)
ABSTRACT Disclosed herein are methods of treatment of autoimmune diseases such as systemic lupus erythematosus (SLE) as well as clinical assays for detection of autoimmune disease activity in patients utilizing a PD1 ligand.
FILED Monday, August 05, 2019
APPL NO 16/532435
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0082 (20130101)
A61B 5/4842 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 38/06 (20130101)
A61K 38/06 (20130101)
A61K 38/07 (20130101)
A61K 38/07 (20130101)
A61K 39/3955 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 16/2803 (20130101)
C07K 2317/76 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/564 (20130101) Original (OR) Class
G01N 2333/70503 (20130101)
G01N 2800/56 (20130101)
G01N 2800/102 (20130101)
G01N 2800/104 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 436/811 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860163 Smith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
ASSIGNEE(S) MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York)
INVENTOR(S) Melody Smith (New York, New York);  Marcel van den Brink (New York, New York);  Eric Pamer (Montclair, New Jersey);  Eric Littmann (Brooklyn, New York)
ABSTRACT The present invention relates to compositions, methods, and kits for predicting a subject's response to a CAR T cell therapy, by analyzing the intestinal microbiome of the subject. The present disclosure also provides a method of detecting patients at risk for a poor response to CAR T cell therapy by measuring the level of the presently disclosed bacteria or bacterial genes in the microflora or microbiome of a patient receiving or considered for CAR T cell therapy. The present disclosure further provides therapeutic compositions and methods for treating a subject having a cancer, by improving the subject's response to a CAR T cell therapy.
FILED Tuesday, April 13, 2021
APPL NO 17/229184
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 35/74 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56911 (20130101) Original (OR) Class
G01N 2496/00 (20130101)
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860164 Greene et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) FRED HUTCHINSON CANCER CENTER (Seattle, Washington)
ASSIGNEE(S) Fred Hutchinson Cancer Center (Seattle, Washington)
INVENTOR(S) Evan Greene (Seattle, Washington);  Greg Finak (Lake Forest Park, Washington);  Raphael Gottardo (Seattle, Washington)
ABSTRACT Disclosed herein are to markers, methods and systems for identifying cell populations, diagnosing, monitoring and treating cancer, including biomarkers predictive of response to immunotherapy treatment in Merkel cell carcinoma.
FILED Thursday, June 11, 2020
APPL NO 16/899476
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5743 (20130101) Original (OR) Class

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 5/00 (20190201)
G16B 25/10 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860172 Cooks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Livia Schiavinato Eberlin (Lafayette, Indiana);  Christina Ramires Ferreira (West Lafayette, Indiana);  Allison Lisa Dill (Indianapolis, Indiana);  Demian R. Ifa (West Lafayette, Indiana)
ABSTRACT The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis. Due to the use of a liquid phase that does not destroy native tissue morphology during analysis, a subsequent staining technique can be performed on the tissue sample and an overlaid image can be produced of a mass spectral image and a staining image.
FILED Wednesday, May 26, 2021
APPL NO 17/331264
ART UNIT 1796 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/92 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 49/0004 (20130101)
H01J 49/0036 (20130101)
H01J 49/142 (20130101)
H01J 49/165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860256 Fu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of The University of Arizona (Tucson, Arizona)
INVENTOR(S) Zhiyang Fu (Tucson, Arizona);  Maria I. Altbach (Tucson, Arizona);  Ali Bilgin (Tucson, Arizona)
ABSTRACT A method for producing a streak-suppressed MR image of a subject includes (i) generating an interference correlation matrix from M coil images, (ii) producing eigenvectors of the interference correlation matrix, and (iii) determining, from the subspace-eigenvectors, a projection matrix of the interference null space. The subspace-eigenvectors include a plurality of subspace-eigenvectors that span an interference subspace and a plurality of null-space-eigenvectors that span an interference null space. The method also includes generating, from N coil images derived from a respective one of N MR signals, N streak-suppressed multi-coil images by either (i) preprocessing the N coil images with the projection matrix and applying an image-reconstruction technique to each of the resultant N preprocessed coil images, or (ii) applying an image-reconstruction technique to each of the N coil images to obtain N reconstructed coil images and post-processing the resultant N reconstructed coil images with the projection matrix.
FILED Tuesday, April 19, 2022
APPL NO 17/659712
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5608 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 11/005 (20130101)
G06T 11/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860258 Mugler, III et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Virginia Patent Foundation (Charlottesville, Virginia);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland);  Siemens Healthcare GMBH (Erlangen, Germany)
ASSIGNEE(S) UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia);  SIEMENS HEALTHCARE GMBH (Erlangen, Germany);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland)
INVENTOR(S) John P. Mugler, III (Charlottesville, Virginia);  Craig H. Meyer (Charlottesville, Virginia);  Adrienne Campbell (Washington, District of Columbia);  Rajiv Ramasawmy (Bethesda, Maryland);  Josef Pfeuffer (Erlangen, Germany);  Zhixing Wang (Charlottesville, Virginia);  Xue Feng (Zion Crossroads, Virginia)
ABSTRACT Methods, computing devices, and MRI systems that reduce artifacts produced by Maxwell gradient terms in TSE imaging using non-rectilinear trajectories are disclosed. With this technology, a RF excitation pulse is generated to produce transverse magnetization that generates a NMR signal and a series of RF refocusing pulses to produce a corresponding series of NMR spin-echo signals. An original encoding gradient waveform comprising a non-rectilinear trajectory is modified by adjusting a portion of the original encoding gradient waveform or introducing a zero zeroth-moment waveform segment at end(s) of the original encoding gradient waveform. During an interval adjacent to each of the series of RF refocusing pulses a first gradient pulse is generated. At least one of the first gradient pulses is generated according to the modified gradient waveform. An image is constructed from generated digitized samples of the NMR spin-echo signals obtained.
FILED Thursday, April 28, 2022
APPL NO 17/732155
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5618 (20130101)
G01R 33/56581 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860354 Xu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) SCANOGEN INC. (Baltimore, Maryland)
ASSIGNEE(S) Scanogen Inc. (Baltimore, Maryland)
INVENTOR(S) Zhiguang Xu (Malvern, Pennsylvania);  Alfredo Andres Celedon (Columbia, Maryland)
ABSTRACT An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.
FILED Thursday, May 12, 2022
APPL NO 17/743166
ART UNIT 2482 — Recording and Compression
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/04 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101)
G02B 21/16 (20130101)
G02B 21/361 (20130101) Original (OR) Class
G02B 21/365 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11861475 Hu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Leland S. Hu (Phoenix, Arizona);  Jing Li (Tempe, Arizona);  Kristin R. Swanson (Phoenix, Arizona);  Teresa Wu (Gilbert, Arizona);  Nathan Gaw (Tempe, Arizona);  Hyunsoo Yoon (Tempe, Arizona);  Andrea Hawkins-Daarud (Houston, Texas)
ABSTRACT Described here are systems and methods for generating and implementing a hybrid machine learning and mechanistic model to produce biological feature maps, or other measurements of biological features, based on an input of multiparametric magnetic resonance or other images. The hybrid model can include a combination of a machine learning model and a mechanistic model that takes as an input multiparametric MRI, or other imaging, data to generate biological feature maps (e.g., tumor cell density maps), or other measures or predictions of biological features (e.g., tumor cell density). The hybrid models have capabilities of learning individual-specific relationships between imaging features and biological features.
FILED Monday, November 19, 2018
APPL NO 16/764837
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 18/2155 (20230101)

Computer Systems Based on Specific Computational Models
G06N 20/10 (20190101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862338 Iacoviello et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) ICAHN School of Medicine at Mount Sinai (New York, New York)
ASSIGNEE(S) Click Therapeutics, Inc. (New York, New York)
INVENTOR(S) Brian M. Iacoviello (New York, New York);  Dennis Charney (New York, New York)
ABSTRACT The present disclosure relates to systems and methods for accessing a data structure including a subject identifier identifying a subject and a subject connectivity value derived from at least one of a scan or test provided to the subject, the subject connectivity value representing a magnitude of a connection associated with at least one sub-processing region of a nervous system of the subject; comparing the subject connectivity value to a connectivity threshold value to determine a classification of the subject; determining that the subject connectivity value exceeds the connectivity threshold value, storing in the data structure, an association between the subject identifier and a first classification value corresponding to a first classification or determining that the subject connectivity value is less than the connectivity threshold value, and storing in the data structure, an association between the subject identifier and a second classification value corresponding to a second classification.
FILED Wednesday, March 27, 2019
APPL NO 17/041770
ART UNIT 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/165 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/70 (20180101)
G16H 50/20 (20180101) Original (OR) Class
G16H 50/50 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11856945 Singamaneni et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Srikanth Singamaneni (St. Louis, Missouri);  Congzhou Wang (St. Louis, Missouri);  Jeremiah J. Morrissey (St. Louis, Missouri);  Evan D. Kharasch (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Srikanth Singamaneni (St. Louis, Missouri);  Congzhou Wang (St. Louis, Missouri);  Jeremiah J. Morrissey (St. Louis, Missouri);  Evan D. Kharasch (St. Louis, Missouri)
ABSTRACT Methods and systems for preparing and preserving biological samples are disclosed herein. A method comprises contacting a preserving agent with a biological sample to form a mixture, wherein the preserving agent is selected from at least one of a metal-organic framework (MOF) encapsulant or a precursor forming a MOF encapsulant, and wherein the biological sample comprises at least one target analyte. A system comprises a preserving agent selected from at least one of a metal-organic framework (MOF) encapsulant or a precursor forming a MOF encapsulant; and a substrate configured to receive a drop cast mixture of the preserving agent and a biological sample, wherein the biological sample comprises at least one target analyte.
FILED Friday, April 20, 2018
APPL NO 16/606482
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0231 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/4044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857293 Mulligan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Flashback Technologies, Inc. (Boulder, Colorado);  The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S)
INVENTOR(S) Isobel Jane Mulligan (Niwot, Colorado);  Gregory Zlatko Grudic (Niwot, Colorado);  Steven L. Moulton (Littleton, Colorado)
ABSTRACT Novel tools and techniques are provided for assessing, predicting and/or estimating a probability that a patent is bleeding, in some cases, noninvasively. In various embodiments, tools and techniques are provided for implementing rapid detection of bleeding before, during, and after fluid resuscitation, in some instances, in real-time.
FILED Friday, October 16, 2015
APPL NO 14/885888
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/002 (20130101)
A61B 5/029 (20130101)
A61B 5/031 (20130101)
A61B 5/0075 (20130101)
A61B 5/0205 (20130101)
A61B 5/318 (20210101)
A61B 5/369 (20210101)
A61B 5/398 (20210101)
A61B 5/742 (20130101)
A61B 5/02028 (20130101)
A61B 5/02042 (20130101) Original (OR) Class
A61B 5/02108 (20130101)
A61B 5/02241 (20130101)
A61B 5/4836 (20130101)
A61B 5/4875 (20130101)
A61B 5/6826 (20130101)
A61B 5/7246 (20130101)
A61B 5/7267 (20130101)
A61B 5/7275 (20130101)
A61B 5/14551 (20130101)
A61B 7/04 (20130101)
A61B 2562/0219 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/1613 (20140204)
A61M 5/1723 (20130101)
A61M 2005/14208 (20130101)
A61M 2205/50 (20130101)
A61M 2230/04 (20130101)
A61M 2230/005 (20130101)
A61M 2230/10 (20130101)
A61M 2230/30 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/17 (20180101)
G16H 50/50 (20180101)

Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for
G16Z 99/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857343 Hanson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Timothy L. Hanson (San Francisco, California);  Philip N. Sabes (San Francisco, California)
ABSTRACT Methods are provided for the fabrication of microneedles. Microneedles fabricated according to the herein described methods will generally be constructed of multiple lengths of wire winded together, brazed and further manipulated to include a reversible engagement feature. The subject microneedles may find use in a variety of applications and, among other purposes, the reversible engagement feature of such a microneedle may by employed in implanting an implantable device into a biological tissue. Also provided are methods of inserting an implantable device into a biological tissue having an outer membrane. The subject methods may include ablating a section of the outer membrane and inserting the implantable device through the ablated section of outer membrane, including e.g., where the implantable device is inserted using a microneedle including e.g., those microneedles for which methods of fabrication are provided herein.
FILED Tuesday, November 28, 2017
APPL NO 16/463323
ART UNIT 1716 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/685 (20130101) Original (OR) Class
A61B 5/1459 (20130101)
A61B 5/1473 (20130101)
A61B 5/6868 (20130101)
A61B 2562/12 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0028 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0502 (20130101)
A61N 1/0529 (20130101)
A61N 1/0551 (20130101)
A61N 5/0601 (20130101)
A61N 2005/0612 (20130101)
A61N 2005/0651 (20130101)

Working or Processing of Metal Wire
B21F 45/008 (20130101)

Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 1/0008 (20130101)
B23K 2101/32 (20180801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857509 Reshetnyak et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island);  Yale University (New Haven, Connecticut)
ASSIGNEE(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island);  Yale University (New Haven, Connecticut)
INVENTOR(S) Yana K. Reshetnyak (South Kingstown, Rhode Island);  Oleg A. Andreev (South Kingstown, Rhode Island);  Donald M. Engelman (New Haven, Connecticut)
ABSTRACT The present application relates to compositions comprising and methods of using a liposome comprising a pHLIP polypeptide, wherein a lipid bilayer of the liposome is substantially free of the pHLIP polypeptide.
FILED Tuesday, December 17, 2019
APPL NO 16/717577
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/127 (20130101)
A61K 9/1271 (20130101) Original (OR) Class
A61K 31/20 (20130101)
A61K 31/337 (20130101)
A61K 31/704 (20130101)
A61K 31/711 (20130101)
A61K 31/713 (20130101)
A61K 31/7105 (20130101)
A61K 47/6911 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857551 Zuo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) Ting Therapeutics LLC (Omaha, Nebraska)
ASSIGNEE(S) Ting Therapeutics LLC (Omaha, Nebraska)
INVENTOR(S) Jian Zuo (Omaha, Nebraska);  Pezhman Salehi Dermanaki (Elkhorn, Nebraska)
ABSTRACT Acquired hearing loss due to chemotherapy or noise exposure is a major health problem, and cisplatin chemotherapy often causes permanent hearing loss in cancer patients. However, there are no FDA-approved drugs for the treatment or prevention of cisplatin- or noise-induced hearing loss. In one aspect, use of compounds as an active agent to treat a hearing impairment and to prevent a hearing impairment, and methods of treating and/or preventing hearing impairments or disorders using the compositions are disclosed. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Friday, July 09, 2021
APPL NO 17/371847
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 11/00 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 31/513 (20130101)
A61K 31/517 (20130101) Original (OR) Class
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857632 Ray et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) INNOSENSE LLC (Torrance, California)
ASSIGNEE(S) INNOSENSE LLC (Torrance, California)
INVENTOR(S) Anamika Ray (Torrance, Canada);  Cheyann Wetteland (Madison, Wisconsin);  Harini Madakashira (Allen, Texas);  Joseph Kessler (Fullerton, California);  Uma Sampathkumaran (Torrance, California)
ABSTRACT A versatile drug delivery system comprised of plant-based nanocellulose can be used for providing high loading and extended release for virtually any drug. This system is made from nanocrystalline cellulose chemically cross-linked to form a hydrogel. This versatile hydrogel-based drug delivery system can be functionalized to support extended release of oral dosing, relieving patient burden and increasing quality of life.
FILED Thursday, October 24, 2019
APPL NO 16/663335
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/38 (20130101) Original (OR) Class
A61K 47/40 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/20 (20130101)
A61L 27/52 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857737 Franklin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
APPLICANT(S) Prytime Medical Devices, Inc. (Boerne, Texas)
ASSIGNEE(S) Prytime Medical Devices, Inc. (Boerne, Texas)
INVENTOR(S) Curtis J. Franklin (Lakewood, Colorado);  David Spencer (Boerne, Texas);  Todd J. Krummenacher (Lakewood, Colorado)
ABSTRACT An occlusion catheter system includes a proximal hub having an inflation connection port and an inflation pathway. An inflation catheter member is connected to the proximal hub and has an inflation lumen. A stiffener member defines a longitudinal axis. The proximal end of the stiffener member is connected to the proximal hub. The stiffener member extends through a portion of the inflation lumen. An occlusion balloon has a proximal balloon end and a distal balloon end. A distal catheter member is positioned substantially on the longitudinal axis and is connected to the distal end of the stiffener member. An atraumatic tip is positioned on a distal end of the distal catheter member. The atraumatic tip has a substantially circular profile in a relaxed configuration. A pressure sensor is connected to the occlusion catheter system distally relative to the occlusion balloon and is connected to a processor by electrical wiring.
FILED Tuesday, December 28, 2021
APPL NO 17/563669
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/12036 (20130101)
A61B 17/12045 (20130101)
A61B 17/12109 (20130101)
A61B 2017/00017 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/007 (20130101)
A61M 25/008 (20130101)
A61M 25/0068 (20130101) Original (OR) Class
A61M 25/0074 (20130101)
A61M 25/104 (20130101)
A61M 25/1002 (20130101)
A61M 25/1006 (20130101)
A61M 25/10182 (20131105)
A61M 2025/0002 (20130101)
A61M 2025/1052 (20130101)
A61M 2025/1059 (20130101)
A61M 2025/1081 (20130101)
A61M 2025/1084 (20130101)
A61M 2025/1086 (20130101)
A61M 2025/1093 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857806 Fontenot et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Ross S. Fontenot (Montgomery Village, Maryland);  William A. Hollerman (Lafayette, Louisiana);  Noel A. Guardala (Columbia, Maryland)
ABSTRACT Exemplary inventive practice implements Europium Tetrakis Dibenzoylmethide Triethylammonium (EuD4TEA) so as to administer ion beam therapy with extreme precision. An EUD4TEA-inclusive marker (e.g., a solid or gel) is exactingly placed on the skin of a patient in accordance with a predetermined location of cancerous tissue beneath the skin. An ion beam aimed at the EUD4TEA-inclusive marker results in luminescence of at least a portion of the EUD4TEA-inclusive marker, thereby indicating that at least a portion of the ion beam is traveling through the EUD4TEA-inclusive marker and striking the cancer therebelow. According to other modes of exemplary inventive practice, a medical phantom contains a tumor replica that is visibly contrastive inside the medical phantom in terms of luminescence versus non-luminescence. The tumor replica is targeted in ion beam testing to discern optimal geometric and radiative conditions for treating a correspondingly situated patient on the same treatment couch.
FILED Wednesday, July 03, 2019
APPL NO 16/503095
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 90/39 (20160201)
A61B 2090/395 (20160201)
A61B 2090/3941 (20160201)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1049 (20130101) Original (OR) Class
A61N 2005/1051 (20130101)
A61N 2005/1076 (20130101)
A61N 2005/1087 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858517 Gupta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
APPLICANT(S) The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Maanak Gupta (Cookeville, Tennessee);  James Benson (San Antonio, Texas);  Farhan Patwa (San Antonio, Texas);  Ravinderpal Sandhu (Helotes, Texas)
ABSTRACT Embodiments of the present systems and methods may provide techniques that provide dynamic groups and attribute-based access control (ABAC) model (referred as CV-ABACG) to secure communication, data exchange and resource access in smart vehicles ecosystems. In embodiments, the model not only considers system wide attributes-based security policies, but also takes into account individual user privacy preferences for allowing or denying service notifications, alerts, and operations to on-board resources. Embodiments of the present systems and methods may provide groups in vehicular IoT, which may be dynamically assigned to moving entities like connected cars, based on their current GPS coordinates, speed or other attributes, to ensure relevance of location and time sensitive notification services, to provide administrative benefits to manage large numbers of entities, and to enable attributes inheritance for fine-grained authorization policies.
FILED Friday, March 06, 2020
APPL NO 16/811165
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 40/08 (20130101) Original (OR) Class

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0297 (20130101)

Wireless Communication Networks
H04W 4/44 (20180201)
H04W 4/46 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858597 Seeley
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
INVENTOR(S) Eric Seeley (Seabeck, Washington)
ABSTRACT A field configurable autonomous vehicle includes modular elements and attachable components. The vehicle can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed vehicles for each mission. The vehicle can include a mechanisms that magnetically attach and release configurable elements from the vehicle.
FILED Thursday, April 28, 2022
APPL NO 17/731629
ART UNIT 3617 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 3/08 (20130101) Original (OR) Class
B63B 7/04 (20130101)
B63B 73/10 (20200101)

Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 2008/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858610 Adorno et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Ruben Adorno (Dayton, Ohio);  Anthony Palazotto (Dayton, Ohio)
ABSTRACT An apparatus for lifting a load to a desired altitude using an evacuated hollow lift body is disclosed. Once evacuated, the apparatus is lighter than the surrounding atmosphere. The lift body can be formed as a hollow fluid tight structure with a tube wound and sealed in a helical pattern or a dual membrane structure with a pressurized intermediate volume sandwiched between inner and outer membranes. A load can be attached to the apparatus and lifted to an altitude where the effective density of the apparatus and load is equivalent to the density of the surrounding atmosphere.
FILED Friday, July 10, 2020
APPL NO 16/925376
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Lighter-than Air Aircraft
B64B 1/58 (20130101) Original (OR) Class

Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load
B66F 19/00 (20130101)
B66F 2700/09 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858624 Brown
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert Henry Brown (Hanover, Maryland)
ABSTRACT Exemplary inventive practice improves the taxiing dynamics of a seaplane by propulsively imparting roll moments so as to continually encourage levelness of the two wings, thereby maintaining both wings completely above (out of) the water. Two matching motor-driven propellers are correspondingly positioned at or near the wingtips. A computer receives sensory motion inputs and transmits sequential commands that continually adjust the respective propulsive forces of the wingtip propellers by effecting equal and opposite changes in their respective rotational speeds. An increase in one wingtip propeller's rotational speed is concomitant a decrease in the other wingtip propeller's rotational speed, wherein the increase and the decrease are of the same magnitude. The seaplane rolls upward on the wing whose wingtip propeller is increasing in rotational speed. Control of the seaplane's rolling motion is thus enabled by a sustained propulsive equilibrium between the two wingtip propellers.
FILED Thursday, May 19, 2022
APPL NO 17/748067
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 35/001 (20130101) Original (OR) Class

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 31/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858652 Spritzer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Zachary W. Spritzer (Dulles, Virginia);  Vincent J. Sacro (Dulles, Virginia);  Timothy P. Duston (Sterling, Virginia)
ABSTRACT A system and method is provided that captures command and control string data during an unmanned vehicle operation. The control string includes user inputs (e.g., mouse inputs, keyboard inputs, etc.) and display outputs (i.e., data displaying to the user via displays). The control string data is captured and stored during the sortie (i.e., a flight) and the control string is preserved (also referred to as impounded) when a mishap occurred during the sortie.
FILED Thursday, March 25, 2021
APPL NO 17/212160
ART UNIT 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 45/00 (20130101) Original (OR) Class
B64D 2045/0065 (20130101)

Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere
G07C 5/085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858814 Fischer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Felix Raoul Fischer (Berkeley, California);  Gregory Clinton Veber (Berkeley, California)
ABSTRACT The disclosure provides for crystalline graphene nanoribbon-covalent organic frameworks (GNR-COFs) that have a two-dimensional (2D) sheet or film morphology, methods of making thereof, and uses thereof.
FILED Tuesday, September 15, 2020
APPL NO 17/021612
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/194 (20170801) Original (OR) Class
C01B 2204/04 (20130101)
C01B 2204/06 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/77 (20130101)
C01P 2002/82 (20130101)
C01P 2002/89 (20130101)
C01P 2004/02 (20130101)
C01P 2004/03 (20130101)
C01P 2004/04 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858817 Pate et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Bradford B. Pate (Arlington, Virginia);  William Maza (Camp Spring, Maryland);  Vanessa Breslin (Alexandria, Virginia);  Paul A. DeSario (Alexandria, Virginia);  Tatyana I. Feygelson (Springfield, Virginia);  Albert Epshteyn (Potomac, Maryland);  Jeffrey C. Owrutsky (Silver Spring, Maryland);  Carlos Hangarter (Alexandria, Virginia)
ABSTRACT Disclosed is a method of irradiating a composition having water and hydrogen-terminated nanodiamonds with light that generates water-solvated electrons from the nanodiamonds. The method can be used to degrade fluoroalkyl compounds such as perfluorooctane sulfonate.
FILED Wednesday, November 25, 2020
APPL NO 17/104676
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/123 (20130101)
B01J 2219/089 (20130101)
B01J 2219/1203 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/28 (20170801) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2004/64 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858902 Piercey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Davin Glenn Piercey (Lafayette, Indiana);  Dominique Wozniak (Lafayette, Indiana)
ABSTRACT The present disclosure relates to a novel compound suitable for a metal-free primary explosive, and the method of making and using the novel compound. The novel compound can undergo a deflagration to detonation transition (DDT) to initiate detonation of a larger body of secondary explosive. The compound has a structure of Formula I:
FILED Monday, April 05, 2021
APPL NO 17/221866
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 25/00 (20130101)

Heterocyclic Compounds
C07D 249/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858953 Chaput et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) John Chaput (Irvine, California);  Jen-Yu Liao (Irvine, California);  Saikat Bala (Irvine, California)
ABSTRACT The invention provides compositions and methods for synthesis of phosphorylated organic compounds, including nucleoside triphosphates.
FILED Tuesday, May 04, 2021
APPL NO 17/307567
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/711 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 27/138 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/091 (20130101) Original (OR) Class

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859099 Webster et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
ASSIGNEE(S) NDSU RESEARCH FOUNDATION (Fargo, North Dakota)
INVENTOR(S) Dean C. Webster (Fargo, North Dakota);  Alireza Rahimi (N. Royalton, Ohio)
ABSTRACT The invention is directed to curable polyurethane coating compositions which may be used to form fouling release coatings, e.g., for use in protecting boat hulls. A curable coating composition of the invention comprises a) at least one amphiphilic additive; b) at least one polyisocyanate; c) at least one polyol; and d) optionally, at least one amphiphilic PEG-PDMS isocyanate prepolymer. Another curable coating composition of the invention comprises the at least one polyisocyanate, b), the at least one polyol, c), and the at least one amphiphilic PEG-PDMS isocyanate prepolymer, d). The invention further relates to methods for reducing or preventing biofouling of a surface exposed to an aqueous environment comprising the steps of coating the surface with the curable coating compositions of the invention to form a coated surface, and curing the coating composition on the coated surface.
FILED Wednesday, March 03, 2021
APPL NO 17/191035
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/283 (20130101)
C08G 18/289 (20130101)
C08G 18/725 (20130101)
C08G 18/755 (20130101)
C08G 18/792 (20130101)
C08G 18/6229 (20130101)
C08G 18/8064 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/1637 (20130101)
C09D 175/04 (20130101)
C09D 175/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859214 Doherty et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts)
ASSIGNEE(S) The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Laurel A Doherty (Waltham, Massachusetts);  Jason W Soares (Norfolk, Massachusetts);  Steven Arcidiacono (Bellingham, Massachusetts);  Sarah Pearce (Dedham, Massachusetts)
ABSTRACT An in vitro model of an in vivo gastrointestinal tract including an in vitro model of an in vivo small intestine including a plurality of fermentation vessels and an in vitro model of an in vivo large intestine including a plurality of fermentation vessels is provided. A method of simulating a biotransformation of food product through the human digestive tract using an in vitro model of an in vivo gastrointestinal tract is provided.
FILED Thursday, August 15, 2019
APPL NO 16/541469
ART UNIT 1799 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 21/08 (20130101)
C12M 21/18 (20130101)
C12M 23/58 (20130101)
C12M 29/00 (20130101)
C12M 41/18 (20130101)
C12M 41/26 (20130101)
C12M 41/48 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0697 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859321 Dion et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Science Foundation (NSF)
APPLICANT(S) Drexel University (Philadelphia, Pennsylvania);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadephia, Pennsylvania);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Genevieve Eugenie Dion (Philadelphia, Pennsylvania);  Chelsea Elizabeth Amanatides (Philadelphia, Pennsylvania);  Randall Kamien (Philadelphia, Pennsylvania)
ABSTRACT A method for designing a knitted textile or fabric, the method includes receiving graphical input from a user regarding a knit pattern comprised of different types of individual stitches to be included in a textile or fabric design. The method further includes graphically displaying a representation of the textile or fabric design. The method further includes merging sections of continuous stitches of the same type into at least one block. The method further includes graphically displaying the textile or fabric design as a pattern of the at least one block. The method further includes applying edge rolling indicators and/or folding indicators to the displayed pattern of the at least one block, where the edge rolling and/or folding indicators respectively and graphically illustrate predicted edge rolling and folding behaviors of a physical textile or fabric.
FILED Thursday, March 31, 2022
APPL NO 17/710915
ART UNIT 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Knitting
D04B 1/102 (20130101)
D04B 15/80 (20130101)
D04B 21/06 (20130101)
D04B 37/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859921 Kelly et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Kevin W. Kelly (Baton Rouge, Louisiana);  David Craig (Baton Rouge, Louisiana)
ASSIGNEE(S) International Mezzo Technologies, Inc. (Baton Rouge, Louisiana)
INVENTOR(S) Kevin W. Kelly (Baton Rouge, Louisiana);  David Craig (Baton Rouge, Louisiana)
ABSTRACT This invention relates to a light weight microtube heat exchanger that meets all the performance requirements of more conventional plate-fin heat exchangers (thermal performance, shock and vibration, and weight, etc.) while providing significant improvements with respect to air-side fouling due to sand and dirt or weight reduction.
FILED Saturday, February 29, 2020
APPL NO 16/805715
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 15/04 (20130101)
B64D 2013/0618 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 1/10 (20130101)
F28F 9/0246 (20130101)
F28F 19/00 (20130101) Original (OR) Class
F28F 2260/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859972 Lipson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Michal Lipson (New York, New York);  Xingchen Ji (New York, New York);  Alexander Klenner (New York, New York);  Xinwen Yao (Baltimore, Maryland);  Yu Gan (Harriston, New Jersey);  Alexander L. Gaeta (New York, New York);  Christine P Hendon (Bronx, New York)
ABSTRACT A method of providing optical coherence tomography (OCT) imaging may comprise using an on-chip frequency comb source interfaced with an OCT system by a circulator as an imaging source and reconstructing OCT images from resulting spectral data from target tissue illuminated by the imaging source.
FILED Tuesday, July 06, 2021
APPL NO 17/367884
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02008 (20130101) Original (OR) Class
G01B 9/02091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860040 Morris et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Science Applications International Corporation (Reston, Virginia)
ASSIGNEE(S) Science Applications International Corporation (Reston, Virginia)
INVENTOR(S) David M. Morris (Bloomington, Indiana);  John P. Timler (River Ridge, Louisiana)
ABSTRACT Infrared transparent constructs (e.g., infrared transparent windows) may be shaped as a dome (e.g., for an infrared detector system) and/or other desired geometries, such as portions of IR seeker domes. Electrically conductive tracing(s) may be printed in desired shapes and forms, e.g., in the form of EMI shielding, an FSS grid, an anti-static component, electrical connectors, etc., and integrated into the interior of the construct structure. The electrically conductive tracing(s) may be printed between layers of independent infrared transparent window components that are then engaged together to form a window preform. Additionally or alternatively, the electrically conductive tracing(s) may be printed between printed layers of infrared transparent ceramic or plastic material built up to form the window preform. Once formed, the window preform may be sintered, e.g., in an ultrafast high temperature sintering process (and optionally further treated) to produce the final infrared transparent construct.
FILED Friday, January 15, 2021
APPL NO 17/150015
ART UNIT 2881 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/0875 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860088 Youssef et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Science Foundation (NSF)
APPLICANT(S) San Diego State University (SDSU) Foundation (San Diego, California)
ASSIGNEE(S) SAN DIEGO STATE UNIVERSITY (SDSU) FOUNDATION (San Diego, California)
INVENTOR(S) George Youssef (Solana Beach, California);  Nha Uyen Huynh (La Jolla, California)
ABSTRACT A testing apparatus for dynamic characterization of a sample of a material under test. A terahertz (THz) time-domain spectroscopy system is configured and arranged to generate and detect terahertz waves to interrogate the sample. A shock wave loading system is configured and arranged to produce a shock wave in the sample concurrently with said THz spectroscopy device interrogating the sample. The sample undergoes changes in an index of refraction in response to the produced ultrafast shock wave in the sample that are detected by the terahertz spectroscopy system.
FILED Friday, October 30, 2020
APPL NO 17/770277
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/41 (20130101)
G01N 21/3586 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860160 Zenhausern et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Frederic Zenhausern (Chandler, Arizona);  Peng Chen (Chandler, Arizona);  Jian Gu (Chandler, Arizona);  Jerome Lacombe (Chandler, Arizona)
ABSTRACT Provided are vertical flow detection devices and related methods. The devices may comprise a membrane having a first surface and a second surface with a plurality of porous structures extending between the first and second surfaces to form fluid conduits from a first fluid chamber formed by the first surface and a second fluid chamber formed by the second fluid surface. A capture agent is immobilized on and/or in the membrane. A rigid porous membrane support mechanically supports the membrane and to provide a relatively uniform flow across the membrane. Various gaskets or holder elements are positioned around an outer edge of the membrane to prevent fluid leakage around the membrane. A fluid pump is configured to force a fluid sample flow in a direction from the first fluid chamber to the second fluid chamber.
FILED Friday, March 29, 2019
APPL NO 17/040417
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2200/0689 (20130101)
B01L 2300/12 (20130101)
B01L 2300/0877 (20130101)
B01L 2400/0475 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54391 (20210801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860336 Meretska et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Maryna Leonidivna Meretska (Cambridge, Massachusetts);  Soon Wei Daniel Lim (Cambridge, Massachusetts);  Federico Capasso (Cambridge, Massachusetts)
ABSTRACT An optical device includes a membrane. The membrane includes a plurality of apertures extending at least partially through a thickness of the membrane. The membrane is configured to structure incoming light having a wavelength to produce modified light. The wavelength of the incoming light in vacuum is in a range of ultraviolet light and mid-infrared. The membrane is configured to reflect the modified light away from the membrane or transmit the modified light through the membrane. A separation between each of the plurality of apertures is subwavelength relative to the wavelength of the incoming light. A width of each of the plurality of apertures is subwavelength relative to the wavelength of the incoming light. A length of each of the plurality of apertures is wavelength-scale relative to the wavelength of the incoming light.
FILED Wednesday, October 27, 2021
APPL NO 17/512560
ART UNIT 2872 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101) Original (OR) Class
G02B 5/1833 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860345 Oskotsky et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Mark Oskotsky (Mamaroneck, New York);  Daniel Engheben (Commack, New York);  Vincent Lipari (Whitestone, New York);  Michael Russo, Jr. (Roslyn, New York)
ABSTRACT A mid-wave infrared (MWIR) discrete zoom lens for use with remote surveillance and identification having a dual focal length of 9 and 6.39 inches and F #2.8 and F #2, respectively. In one case, a full field of view is about 30.8 degrees for a 9 inch focal length configuration and about 43 degrees for a 6.39 inch focal length configuration. The lens is corrected for monochromatic and chromatic aberrations over the wavelength range 5100 nm-3300 nm. The focal plane may constitute a pixel array consisting of MWIR sensitive material (e.g. InSb, HgCdTe, nBn, SLS, etc.) for use in high-resolution, wide-area imaging applications.
FILED Friday, April 23, 2021
APPL NO 17/238813
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 15/02 (20130101) Original (OR) Class
G02B 26/10 (20130101)
G02B 26/0816 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860420 Srinivasan et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Center for Nanoscale Science and Technology (CNST)
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland);  Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland);  Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland)
INVENTOR(S) Kartik Srinivasan (Rockville, Maryland);  Xiyuan Lu (Montgomery Village, Maryland)
ABSTRACT An optical cavity includes a ring defining an internal boundary and an external boundary, at least one of which is periodically modulated to define a gear-shaped configuration including a plurality of teeth, thereby enabling a plurality of slow-light modes. At least one physical defect may be defined within the periodically modulated internal boundary and/or external boundary to thereby enable at least one localized mode. At least one waveguide is coupled to the ring.
FILED Thursday, February 17, 2022
APPL NO 17/674079
ART UNIT 2874 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/122 (20130101)
G02B 6/12007 (20130101)
G02B 6/29338 (20130101)
G02B 6/29341 (20130101) Original (OR) Class

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 2203/15 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860682 Behandish et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) XEROX CORPORATION (Norwalk, Connecticut)
INVENTOR(S) Morad Behandish (Mountain View, California);  Johan de Kleer (Los Altos, California);  Randi Wang (Cupertino, California)
ABSTRACT The techniques discussed herein generally relate to a method and system for qualitative modeling of and reasoning about the behavior of spatio-temporal physical systems. In some embodiments, qualitative representations based on Tonti diagrams are used to describe lumped or distributed parameter systems. Using a topological structure of the physical system, some embodiments generate qualitative governing equations as symbolic constraints on qualitative state variables. The qualitative constraints may be used to produce a qualitative simulation of the physical system. The qualitative simulation may be used to guide conceptual design iterations with given design criteria, or for instantiation of quantitative or hybrid (qualitative and quantitative) models and simulations.
FILED Monday, December 23, 2019
APPL NO 16/724983
ART UNIT 2146 — Optics
CURRENT CPC
Electric Digital Data Processing
G06F 30/20 (20200101) Original (OR) Class
G06F 30/23 (20200101)
G06F 2111/04 (20200101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860995 Shannon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) United States of America, as represented by the Secretary of the Navy (Patuxent River, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Russell Shannon (Mays Landing, New Jersey);  Joseph Garcia (La Plata, Maryland);  Aaron Jacobson (King George, Virginia);  William Mosca (Morristown, New Jersey);  Roberto Maldonado (Lusby, Maryland);  Michael Burger (Toms River, New Jersey)
ABSTRACT A method to implement traceability and provability on a particular project in software development based on blockchain-recorded transactions of assigned developer time, the method comprising of the following steps: setting up a blockchain network comprised of a distributed, redundant, and tamper-resistant ledger; issuing each user an attestable pre-fabricated and signed virtualized environment on approved hardware that comes with functionality required for the user's role implemented as one of a set of virtual machine templates fashioned from a signed and approved pre-fabricated image; and verifying that assigned developer time is valid, and if so, record each development action on the ledger to enable extensive tracking and auditing of end-to-end software development process.
FILED Friday, August 13, 2021
APPL NO 17/401847
ART UNIT 2439 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/53 (20130101) Original (OR) Class
G06F 21/54 (20130101)
G06F 21/552 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/50 (20220501)
H04L 9/3236 (20130101)
H04L 9/3247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11861150 Keel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Paul Erich Keel (Cambridge, Massachusetts)
ASSIGNEE(S) Paul Erich Keel (Cambridge, Massachusetts)
INVENTOR(S) Paul Erich Keel (Cambridge, Massachusetts);  Jeffrey Huang (Lausanne, Switzerland)
ABSTRACT A computer-implemented method for interacting with at least one data item obtained from at least one source utilizes computer processes responsive to a user selection of the at least one data item and include causing configuring of each of the data items into a distinct information object by extracting, from each data item, extracted data including a picture, a heading, and a link to the data item, and causing storing of data corresponding to each of the information objects in a database system. The processes further include displaying a representation of each of at least two of the information objects in the database system, the representation being in a uniform format, wherein the format includes a card, and, within the card, in uniform locations thereof, the picture, the heading, a set of indicators, and a set of graphically accessible functions.
FILED Friday, May 07, 2021
APPL NO 17/314953
ART UNIT 2173 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 3/0482 (20130101)
G06F 3/04817 (20130101)
G06F 3/04842 (20130101) Original (OR) Class
G06F 16/22 (20190101)
G06F 16/29 (20190101)
G06F 16/258 (20190101)
G06F 16/9535 (20190101)
G06F 16/9537 (20190101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/10 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 51/046 (20130101)
H04L 67/10 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 707/99933 (20130101)
Y10S 707/99943 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11861437 Swager et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy Manning Swager (Newton, Massachusetts);  Joseph Michael Azzarelli (Cambridge, Massachusetts);  Jens Bomholdt Ravnsbæk (Fredericia, Denmark);  Katherine Andrea Mirica (Waltham, Massachusetts)
ABSTRACT A method of detecting a stimulus can include detecting an output from a radio frequency identification tag including a sensor. A smartphone-based sensing strategy can use chemiresponsive nanomaterials integrated into the circuitry of commercial Near Field Communication tags to achieve non-line-of-sight, portable, and inexpensive detection and discrimination of gas phase chemicals (e.g., ammonia, hydrogen peroxide, cyclohexanone, and water) at part-per-thousand and part-per-million concentrations.
FILED Monday, December 17, 2018
APPL NO 16/223021
ART UNIT 2632 — Digital Communications
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/04 (20130101)
G01N 33/0075 (20130101)

Electric Digital Data Processing
G06F 3/014 (20130101)

Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 19/0716 (20130101) Original (OR) Class
G06K 19/0717 (20130101)
G06K 19/0723 (20130101)
G06K 19/07749 (20130101)
G06K 19/07788 (20130101)

Transmission Systems for Measured Values, Control or Similar Signals
G08C 17/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11861735 Lee et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Gilbert F. Lee (Greenbelt, Maryland);  Ruth A. Maticic (Elkridge, Maryland);  Tami L Ellinger (Laurel, Maryland);  Deborah H. Russell (Friendship, Maryland)
ASSIGNEE(S) The United States of America, as respresented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Gilbert F. Lee (Greenbelt, Maryland);  Ruth A. Maticic (Elkridge, Maryland);  Tami L Ellinger (Laurel, Maryland);  Deborah H. Russell (Friendship, Maryland)
ABSTRACT According to exemplary inventive practice, a transaction code is selected in an ERP system. The transaction code is characterized by cost elements that to a substantial degree entail OM&S costs. ERP reports are generated by drilling down from the cost elements to commitment costs, obligation costs, and actual costs, wherein drilling down from each cost element yields at least one of these three kinds of costs. Raw worksheets are generated in a spreadsheet program by importing data from the ERP reports, wherein each raw worksheet contains data from at least one ERP report. Data are derived from the raw worksheets and are combined and arranged to produce intermediate pivot tables, wherein each intermediate pivot table contains data from at least on raw worksheet. Data are derived from the intermediate pivot tables and are combined and arranged to produce a master worksheet. Data are derived from the master worksheet and are combined and arranged to produce summary pivot tables.
FILED Friday, September 04, 2020
APPL NO 17/012890
ART UNIT 3687 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Electric Digital Data Processing
G06F 40/18 (20200101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/06313 (20130101)
G06Q 10/06315 (20130101)
G06Q 40/125 (20131203) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11861940 Mittal et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
ASSIGNEE(S) UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland)
INVENTOR(S) Trisha Mittal (College Park, Maryland);  Aniket Bera (Greenbelt, Maryland);  Uttaran Bhattacharya (College Park, Maryland);  Rohan Chandra (College Park, Maryland);  Pooja Guhan (College Park, Maryland);  Dinesh Manocha (Greenbelt, Maryland)
ABSTRACT Systems, methods, apparatuses, and computer program products for recognizing human emotion in images or video. A method for recognizing perceived human emotion may include receiving a raw input. The raw input may be processed to generate input data corresponding to at least one context. Features from the raw input data may be extracted to obtain a plurality of feature vectors and inputs. The plurality of feature vectors and the inputs may be transmitted to a respective neural network. At least some of the plurality of feature vectors may be fused to obtain a feature encoding. Additional feature encodings may be computed from the plurality of feature vectors via the respective neural network. A multi-label emotion classification of a primary agent may be performed in the raw input based on the feature encoding and the additional feature encodings.
FILED Wednesday, June 16, 2021
APPL NO 17/349732
ART UNIT 2631 — Digital Communications
CURRENT CPC
Electric Digital Data Processing
G06F 18/253 (20230101)
G06F 18/2431 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101)
G06V 10/803 (20220101)
G06V 20/35 (20220101)
G06V 40/20 (20220101)
G06V 40/103 (20220101)
G06V 40/174 (20220101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862716 Jonker et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Berend T. Jonker (Waldorf, Maryland);  Connie H. Li (Alexandria, Virginia);  Kathleen M. McCreary (Washington, District of Columbia);  Olaf M. J. van 't Erve (Falls Church, Virginia)
ABSTRACT Heterostructures include a layer of a two-dimensional material placed on a multiferroic layer. An ordered array of differing polarization domains in the multiferroic layer produces corresponding domains having differing properties in the two-dimensional material. When the multiferroic layer is ferroelectric, the ferroelectric polarization domains in the layer produce local electric fields that penetrate the two-dimensional material. The local electric fields modulate the charge carriers and carrier density on a nanometer length scale, resulting in the formation of lateral p-n or p-i-n junctions, and variations thereof appropriate for device functions.
FILED Wednesday, September 28, 2022
APPL NO 17/955072
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/4141 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/187 (20130101)
H01L 21/0242 (20130101)
H01L 21/0262 (20130101)
H01L 21/02381 (20130101)
H01L 21/02488 (20130101)
H01L 21/02568 (20130101)
H01L 21/02658 (20130101)
H01L 29/24 (20130101)
H01L 29/778 (20130101)
H01L 29/861 (20130101)
H01L 29/7391 (20130101)
H01L 29/66977 (20130101) Original (OR) Class
H01L 29/78696 (20130101)
H01L 33/002 (20130101)
H01L 33/04 (20130101)
H01L 33/26 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862870 Kaddour et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Abdul-Sattar Kaddour (Miami, Florida);  Stavros Georgakopoulos (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Abdul-Sattar Kaddour (Miami, Florida);  Stavros Georgakopoulos (Miami, Florida)
ABSTRACT Antenna arrays with three-dimensional (3D) conformal radiating elements are provided, as well as methods of manufacturing and methods of using the same. An array can include a ground plane and a plurality of unit cells disposed thereon. Each unit cell can include a 3D conformal radiating element. The 3D conformal radiating elements can be, for example, patches (e.g., circular 3D patches), dipoles, or loops, and each radiating element is conformal on a hemispherical shape.
FILED Friday, December 09, 2022
APPL NO 18/063942
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 5/48 (20150115) Original (OR) Class
H01Q 15/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862879 Boryssenko
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) SI2 Technologies, Inc. (North Billerica, Massachusetts)
ASSIGNEE(S) SI2 Technologies, Inc. (North Billerica, Massachusetts)
INVENTOR(S) Anatoliy Boryssenko (Belchertown, Massachusetts)
ABSTRACT Antenna elements are described that may include a radiator, a feeding portion, a first impedance transformer, a balun, and a second impedance transformer. The first impedance transformer, balun, and second impedance transformer may be disposed above a ground plane of an antenna array to reduce a bulk of the array. The array can also include a dielectric top layer for loading apertures of the antenna array. The antenna elements can also include anomaly suppressors can be provided to cancel common-mode resonances from the radiators.
FILED Monday, March 21, 2022
APPL NO 17/699843
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 9/16 (20130101) Original (OR) Class
H01Q 9/065 (20130101)
H01Q 21/0006 (20130101)
H01Q 21/062 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11863239 Petersen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) L3Harris Technologies, Inc. (Melbourne, Florida)
ASSIGNEE(S) L3Harris Technologies, Inc. (Melbourne, Florida)
INVENTOR(S) Timothy Petersen (Camden, New Jersey);  Richard Winslow (Fort Wayne, Indiana)
ABSTRACT Techniques of present disclosure are directed to methods of providing acoustic communication networks. For example, methods are provided for that include obtaining, at a first transceiver of a plurality of transceivers arranged within an installation pattern, a first acoustic signal provided by a second transceiver of the plurality of transceivers. A location of the first transceiver within a message distribution pattern is determined from the acoustic signal. A delay based upon the location of the first transceiver within the message distribution pattern is determined. Finally, a second acoustic signal corresponding to the first acoustic signal is provided from the first transceiver after the delay.
FILED Friday, February 11, 2022
APPL NO 17/669606
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Transmission
H04B 11/00 (20130101) Original (OR) Class
H04B 13/02 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/0428 (20130101)

Wireless Communication Networks
H04W 64/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11863456 Burnett et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S) ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota)
INVENTOR(S) Benjamin L Burnett (Prior Lake, Minnesota);  Deborah K. Charan (Minneapolis, Minnesota);  Ian J. McLinden (Minneapolis, Minnesota);  Jordan C. Bonney (Bloomington, Minnesota)
ABSTRACT This disclosure is directed to network optimization in a complex joint network for increasing the network utility of the complex joint network. A computing device in the complex joint network may receive a data flow via a complex joint network. The computing device may determine, based on a network template, a mission utility associated with the data flow and a traffic class associated with the data flow. The computing device may control one or more quality of service decisions based at least in part on the mission utility associated with the data flow and the traffic class associated with the data flow.
FILED Tuesday, September 06, 2022
APPL NO 17/929926
ART UNIT 2459 — Computer Networks
CURRENT CPC
Transmission
H04B 7/0617 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/0816 (20130101)
H04L 41/0843 (20130101)
H04L 41/0886 (20130101)
H04L 45/02 (20130101)
H04L 47/762 (20130101)
H04L 47/781 (20130101)
H04L 47/2441 (20130101) Original (OR) Class

Wireless Communication Networks
H04W 8/04 (20130101)
H04W 16/28 (20130101)
H04W 76/19 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11863578 Speck et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Jacquelin A. Speck (Philadelphia, Pennsylvania);  Thomas Heverin (Philadelphia, Pennsylvania);  Mark Roman (Aston, Pennsylvania);  Marcello Balduccini (Wynnewood, Pennsylvania);  Matthew Bosack (Philadelphia, Pennsylvania)
ABSTRACT A Cyber Vulnerability Assessment Tool (CVAST) and CVAST Threat Assessment Heuristic (CVAST THRASH) capable of automated modeling of cyber physical systems, assessment of the nature of cyber risks thereto, and output of such cyber risk assessments are provided.
FILED Thursday, October 15, 2020
APPL NO 16/949154
ART UNIT 2431 — Cryptography and Security
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/01 (20230101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1433 (20130101) Original (OR) Class
H04L 2012/40286 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11864140 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Warfare Center (NAWC)
APPLICANT(S) Intelligent Fusion Technology, Inc. (Germantown, Maryland)
ASSIGNEE(S) INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland)
INVENTOR(S) Dan Shen (Germantown, Maryland);  Genshe Chen (Germantown, Maryland);  Khanh Pham (Kirtland AFB, New Mexico);  Erik Blasch (Arlington, Virginia)
ABSTRACT A system and method are provided for enhanced multi-way time transfer for time synchronization between at least one slave node and one master node. A slave node sends a first message to the master node to launch a time synchronization between the slave node and the master node. Upon receiving the first message, the master node adds a receiving time on a master clock to the first message to form a second message. The master node sends the second message back to the slave node and the slave node adds a receiving time on the slave clock to the second message to form an updated message. The slave node performs a time adjustment to the slave clock based on the updated message, thereby synchronizing time between the slave node and the master node.
FILED Wednesday, January 19, 2022
APPL NO 17/579348
ART UNIT 2632 — Digital Communications
CURRENT CPC
Aeroplanes; Helicopters
B64C 39/024 (20130101)

Transmission
H04B 7/026 (20130101)

Wireless Communication Networks
H04W 56/0015 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11856948 Veleva
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) BENANOVA INC. (Cary, North Carolina)
ASSIGNEE(S) BENANOVA INC. (Cary, North Carolina)
INVENTOR(S) Anka Veleva (Cary, North Carolina)
ABSTRACT Disclosed is a method for creating a composite colloidal particle formulation with advanced functionality that possesses highly efficient and effective properties. The composite colloidal particle formulation comprises an engineered biodegradable particle core dispersed in a bioadhesive polyelectrolyte solution. Also disclosed are methods of use of the same, including but not limited to applying said formulation to plants for disease treatment.
FILED Thursday, December 16, 2021
APPL NO 17/644745
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 25/04 (20130101)
A01N 25/10 (20130101)
A01N 25/22 (20130101) Original (OR) Class
A01N 59/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857293 Mulligan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Flashback Technologies, Inc. (Boulder, Colorado);  The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S)
INVENTOR(S) Isobel Jane Mulligan (Niwot, Colorado);  Gregory Zlatko Grudic (Niwot, Colorado);  Steven L. Moulton (Littleton, Colorado)
ABSTRACT Novel tools and techniques are provided for assessing, predicting and/or estimating a probability that a patent is bleeding, in some cases, noninvasively. In various embodiments, tools and techniques are provided for implementing rapid detection of bleeding before, during, and after fluid resuscitation, in some instances, in real-time.
FILED Friday, October 16, 2015
APPL NO 14/885888
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/002 (20130101)
A61B 5/029 (20130101)
A61B 5/031 (20130101)
A61B 5/0075 (20130101)
A61B 5/0205 (20130101)
A61B 5/318 (20210101)
A61B 5/369 (20210101)
A61B 5/398 (20210101)
A61B 5/742 (20130101)
A61B 5/02028 (20130101)
A61B 5/02042 (20130101) Original (OR) Class
A61B 5/02108 (20130101)
A61B 5/02241 (20130101)
A61B 5/4836 (20130101)
A61B 5/4875 (20130101)
A61B 5/6826 (20130101)
A61B 5/7246 (20130101)
A61B 5/7267 (20130101)
A61B 5/7275 (20130101)
A61B 5/14551 (20130101)
A61B 7/04 (20130101)
A61B 2562/0219 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/1613 (20140204)
A61M 5/1723 (20130101)
A61M 2005/14208 (20130101)
A61M 2205/50 (20130101)
A61M 2230/04 (20130101)
A61M 2230/005 (20130101)
A61M 2230/10 (20130101)
A61M 2230/30 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/17 (20180101)
G16H 50/50 (20180101)

Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for
G16Z 99/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857631 Jeffries et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Nursing Research (NINR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Eric M. Jeffries (West New York, New Jersey);  Yadong Wang (Bradford Woods, Pennsylvania);  Daniel Long (Pittsburgh, Pennsylvania);  Noah R. Johnson (Pittsburgh, Pennsylvania)
ABSTRACT Compositions are provided herein comprising a coacervate of a polycationic polymer, a polyanionic polymer, and platelet-rich plasma and/or serum, or a fraction or concentrate thereof. The composition is useful in wound healing. Compositions also are provided that comprise a hydrogel comprising TIMP-3; and a complex of a polycationic polymer, a polyanionic polymer, FGF-2 and SDF-1α embedded in the hydrogel, which is useful in treating a myocardial infarction.
FILED Tuesday, November 23, 2021
APPL NO 17/533958
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0019 (20130101)
A61K 35/16 (20130101)
A61K 35/19 (20130101)
A61K 38/18 (20130101)
A61K 38/177 (20130101)
A61K 38/195 (20130101)
A61K 38/1825 (20130101)
A61K 47/34 (20130101)
A61K 47/36 (20130101) Original (OR) Class
A61K 47/42 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 15/40 (20130101)
A61L 15/44 (20130101)
A61L 15/225 (20130101)
A61L 15/225 (20130101)
A61L 27/18 (20130101)
A61L 27/20 (20130101)
A61L 27/26 (20130101)
A61L 27/26 (20130101)
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 27/225 (20130101)
A61L 27/3616 (20130101)
A61L 31/16 (20130101)
A61L 31/041 (20130101)
A61L 31/042 (20130101)
A61L 31/046 (20130101)
A61L 31/145 (20130101)
A61L 2300/25 (20130101)
A61L 2300/252 (20130101)
A61L 2300/414 (20130101)
A61L 2300/418 (20130101)
A61L 2400/04 (20130101)
A61L 2430/20 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Compositions of Macromolecular Compounds
C08L 5/10 (20130101)
C08L 5/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857701 Mayes et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Bioengineering and Environmental Systems (BES)
APPLICANT(S) Board Of Regents, The University Of Texas System (Austin, Texas)
ASSIGNEE(S) Board Of Regents, The University Of Texas System (Austin, Texas)
INVENTOR(S) Sarah Mayes (Austin, Texas);  Christine E. Schmidt (Gainesville, Florida)
ABSTRACT A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components.
FILED Monday, May 22, 2023
APPL NO 18/321238
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/192 (20130101)
A61K 31/195 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 31/16 (20130101)
A61L 31/041 (20130101) Original (OR) Class
A61L 31/145 (20130101)
A61L 31/148 (20130101)
A61L 2300/43 (20130101)
A61L 2300/62 (20130101)
A61L 2300/414 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857837 Wechsler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
National Institute on Drug Abuse (NIDA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Emily Wechsler (Dallas, Texas);  Ryan Halter (Lyme, New Hampshire);  John A. Batsis (Hanover, New Hampshire)
ABSTRACT Devices and methods are disclosed for remote clinical monitoring performance of exercises using an instrumented resistance device (100). An example device (100) includes a resistance band (120) having a first end (122) and a second end (124). A first handle (130) connected to the first end (122) and a second handle (140) connected to the second end (124) of the resistance band (120). The device (100) further includes a force sensing assembly (150) positioned between the first handle (130) and the first end (122). The force sensing assembly (150) includes a force sensor (156) connected to the resistance band (120), a microcontroller (182) connected to the force sensor (156) to receive a set of load force measurements from the force sensor (156), and a communication module (184) connected to the microcontroller (182) to transmit the set of load force measurements to a local data receiving device (170).
FILED Friday, May 17, 2019
APPL NO 17/055412
ART UNIT 3784 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 21/00043 (20130101)
A63B 21/0552 (20130101)
A63B 21/4035 (20151001)
A63B 24/0062 (20130101) Original (OR) Class
A63B 2220/17 (20130101)
A63B 2220/51 (20130101)
A63B 2220/62 (20130101)
A63B 2220/833 (20130101)
A63B 2225/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858213 Chen et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Yong Chen (Los Angeles, California);  Jie Jin (Los Angeles, California)
ABSTRACT A system for additively manufacturing a build part. The system includes a build platform configured for disposition within a resin tank, and a light source configured to cure a layer of resin. The layer of resin is disposed adjacent to a pre-cure build surface of the build part. The system also includes a constrained surface located between the build platform and the light source and configured to form a boundary for the layer of resin disposed between the constrained surface and the pre-cure build surface. The constrained surface is configured to vibrate to reduce a separation force required to separate the constrained surface from a post-cure build surface of the build part. The system also includes a vibratory source configured to vibrate the constrained surface.
FILED Thursday, June 13, 2019
APPL NO 16/440780
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/10 (20170801)
B29C 64/205 (20170801)
B29C 64/245 (20170801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858517 Gupta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
APPLICANT(S) The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Maanak Gupta (Cookeville, Tennessee);  James Benson (San Antonio, Texas);  Farhan Patwa (San Antonio, Texas);  Ravinderpal Sandhu (Helotes, Texas)
ABSTRACT Embodiments of the present systems and methods may provide techniques that provide dynamic groups and attribute-based access control (ABAC) model (referred as CV-ABACG) to secure communication, data exchange and resource access in smart vehicles ecosystems. In embodiments, the model not only considers system wide attributes-based security policies, but also takes into account individual user privacy preferences for allowing or denying service notifications, alerts, and operations to on-board resources. Embodiments of the present systems and methods may provide groups in vehicular IoT, which may be dynamically assigned to moving entities like connected cars, based on their current GPS coordinates, speed or other attributes, to ensure relevance of location and time sensitive notification services, to provide administrative benefits to manage large numbers of entities, and to enable attributes inheritance for fine-grained authorization policies.
FILED Friday, March 06, 2020
APPL NO 16/811165
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 40/08 (20130101) Original (OR) Class

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0297 (20130101)

Wireless Communication Networks
H04W 4/44 (20180201)
H04W 4/46 (20180201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858814 Fischer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Felix Raoul Fischer (Berkeley, California);  Gregory Clinton Veber (Berkeley, California)
ABSTRACT The disclosure provides for crystalline graphene nanoribbon-covalent organic frameworks (GNR-COFs) that have a two-dimensional (2D) sheet or film morphology, methods of making thereof, and uses thereof.
FILED Tuesday, September 15, 2020
APPL NO 17/021612
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/194 (20170801) Original (OR) Class
C01B 2204/04 (20130101)
C01B 2204/06 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/77 (20130101)
C01P 2002/82 (20130101)
C01P 2002/89 (20130101)
C01P 2004/02 (20130101)
C01P 2004/03 (20130101)
C01P 2004/04 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858816 Li et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Weigu Li (Austin, Texas);  Donglei Fan (Austin, Texas)
ABSTRACT Disclosed herein are dendritically porous three-dimensional structures, including hierarchical dendritically porous three-dimensional structures. The structures include metal foams and graphite structures, and are useful in energy storage devices as well as chemical catalysis.
FILED Tuesday, August 09, 2022
APPL NO 17/883851
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/205 (20170801) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/85 (20130101)
C01P 2004/03 (20130101)
C01P 2006/10 (20130101)
C01P 2006/12 (20130101)
C01P 2006/16 (20130101)
C01P 2006/40 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/26 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 1/003 (20130101)
C25D 1/006 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/24 (20130101)
H01G 11/36 (20130101)
H01G 11/86 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858877 Camacho et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
NSF Graduate Research Fellowship Program (GRFP)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Carlos Jaime Camacho (Pittsburgh, Pennsylvania);  Robin E. C. Lee (Pittsburgh, Pennsylvania)
ABSTRACT Provided herein are small molecules that specifically inhibit TNF-induced nuclear factor kB (NF-kB) inflammation pathway. Also provided are methods of screening compounds to identify molecules that specifically inhibit a TNF-induced NF-kB inflammation pathway, methods of inhibiting TNF-induced NF-kB inflammation pathway, and methods of preventing formation of mature TNFR1 complex.
FILED Monday, February 24, 2020
APPL NO 16/799130
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)

Acyclic or Carbocyclic Compounds
C07C 233/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859230 Minty et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Jeremy Minty (Ann Arbor, Michigan);  Marc E. Singer (Ann Arbor, Michigan);  Xiaoxia Lin (Ann Arbor, Michigan);  David Boyer (Ann Arbor, Michigan)
ABSTRACT Provided herein are compositions and method for producing γ-polyglutamic acid (PGA). In particular, provided herein are bacterial co-culture systems and methods for producing PGA.
FILED Friday, May 26, 2017
APPL NO 16/304336
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/58 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/48 (20130101) Original (OR) Class
C12P 13/02 (20130101)
C12P 39/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859242 Ly et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Danith H. Ly (Pittsburgh, Pennsylvania);  Wei-Che Hsieh (New Taipei, Taiwan);  Raman Bahal (Glastonbury, Connecticut)
ABSTRACT Described herein are genetic recognition reagents comprising terminal aromatic moieties that bind specifically to a template nucleic acid and concatenate. Also provided are methods of using the genetic recognition reagents, e.g., to treat or diagnose a repeat expansion disorder, such as DMI.
FILED Friday, December 21, 2018
APPL NO 16/955593
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)
C07H 21/04 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859321 Dion et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Science Foundation (NSF)
APPLICANT(S) Drexel University (Philadelphia, Pennsylvania);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) Drexel University (Philadephia, Pennsylvania);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Genevieve Eugenie Dion (Philadelphia, Pennsylvania);  Chelsea Elizabeth Amanatides (Philadelphia, Pennsylvania);  Randall Kamien (Philadelphia, Pennsylvania)
ABSTRACT A method for designing a knitted textile or fabric, the method includes receiving graphical input from a user regarding a knit pattern comprised of different types of individual stitches to be included in a textile or fabric design. The method further includes graphically displaying a representation of the textile or fabric design. The method further includes merging sections of continuous stitches of the same type into at least one block. The method further includes graphically displaying the textile or fabric design as a pattern of the at least one block. The method further includes applying edge rolling indicators and/or folding indicators to the displayed pattern of the at least one block, where the edge rolling and/or folding indicators respectively and graphically illustrate predicted edge rolling and folding behaviors of a physical textile or fabric.
FILED Thursday, March 31, 2022
APPL NO 17/710915
ART UNIT 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Knitting
D04B 1/102 (20130101)
D04B 15/80 (20130101)
D04B 21/06 (20130101)
D04B 37/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859972 Lipson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Michal Lipson (New York, New York);  Xingchen Ji (New York, New York);  Alexander Klenner (New York, New York);  Xinwen Yao (Baltimore, Maryland);  Yu Gan (Harriston, New Jersey);  Alexander L. Gaeta (New York, New York);  Christine P Hendon (Bronx, New York)
ABSTRACT A method of providing optical coherence tomography (OCT) imaging may comprise using an on-chip frequency comb source interfaced with an OCT system by a circulator as an imaging source and reconstructing OCT images from resulting spectral data from target tissue illuminated by the imaging source.
FILED Tuesday, July 06, 2021
APPL NO 17/367884
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/02008 (20130101) Original (OR) Class
G01B 9/02091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860084 Wolf et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) GEORGETOWN UNIVERSITY (Washington, District of Columbia)
ASSIGNEE(S) GEORGETOWN UNIVERSITY (Washington, District of Columbia)
INVENTOR(S) Christian Wolf (Arlington, Virginia);  Zeus A. O. De Los Santos (Washington, District of Columbia);  Ciaran Lynch (Washington, District of Columbia)
ABSTRACT The present invention relates to an analytical method that includes providing a sample potentially containing a chiral analyte that can exist in stereoisomeric forms, and providing a probe selected from the group consisting of metal salts. The sample is contacted with the probe under conditions that permit coordination of the probe to the analyte, if present in the sample; and, based on any coordination that occurs, the absolute configuration of the analyte in the sample, and/or the concentration of the analyte in the sample, and/or the enantiomeric composition of the analyte in the sample is/are determined.
FILED Wednesday, September 11, 2019
APPL NO 17/275471
ART UNIT 2877 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/19 (20130101) Original (OR) Class
G01N 21/77 (20130101)
G01N 2021/7786 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860088 Youssef et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
National Science Foundation (NSF)
APPLICANT(S) San Diego State University (SDSU) Foundation (San Diego, California)
ASSIGNEE(S) SAN DIEGO STATE UNIVERSITY (SDSU) FOUNDATION (San Diego, California)
INVENTOR(S) George Youssef (Solana Beach, California);  Nha Uyen Huynh (La Jolla, California)
ABSTRACT A testing apparatus for dynamic characterization of a sample of a material under test. A terahertz (THz) time-domain spectroscopy system is configured and arranged to generate and detect terahertz waves to interrogate the sample. A shock wave loading system is configured and arranged to produce a shock wave in the sample concurrently with said THz spectroscopy device interrogating the sample. The sample undergoes changes in an index of refraction in response to the produced ultrafast shock wave in the sample that are detected by the terahertz spectroscopy system.
FILED Friday, October 30, 2020
APPL NO 17/770277
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/41 (20130101)
G01N 21/3586 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860118 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) XiuJun Li (El Paso, Texas);  Wan Zhou (El Paso, Texas)
ABSTRACT A biosensing system configured to detect a target DNA and methods of detecting a target DNS are presented. The biosensing system comprises a biosensor comprising a suspension of a hybridization buffer containing dispersed gold nanoparticles, sodium chloride, and single-stranded DNA probes configured to undergo DNA hybridization with the target DNA.
FILED Friday, December 04, 2020
APPL NO 17/112841
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 35/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3276 (20130101)
G01N 27/3277 (20130101)
G01N 27/3278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860336 Meretska et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Maryna Leonidivna Meretska (Cambridge, Massachusetts);  Soon Wei Daniel Lim (Cambridge, Massachusetts);  Federico Capasso (Cambridge, Massachusetts)
ABSTRACT An optical device includes a membrane. The membrane includes a plurality of apertures extending at least partially through a thickness of the membrane. The membrane is configured to structure incoming light having a wavelength to produce modified light. The wavelength of the incoming light in vacuum is in a range of ultraviolet light and mid-infrared. The membrane is configured to reflect the modified light away from the membrane or transmit the modified light through the membrane. A separation between each of the plurality of apertures is subwavelength relative to the wavelength of the incoming light. A width of each of the plurality of apertures is subwavelength relative to the wavelength of the incoming light. A length of each of the plurality of apertures is wavelength-scale relative to the wavelength of the incoming light.
FILED Wednesday, October 27, 2021
APPL NO 17/512560
ART UNIT 2872 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101) Original (OR) Class
G02B 5/1833 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11861049 Venkataramani et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) The George Washington University (Washington, District of Columbia)
INVENTOR(S) Guru Prasadh V. Venkataramani (Fairfax, Virginia);  Milos Doroslovacki (Washington, District of Columbia);  Fan Yao (Orlando, Florida);  Hongyu Fang (North Bethesda, Maryland)
ABSTRACT A system and method for defense against cache timing channel attacks using cache management hardware is provided. Sensitive information leakage is a growing security concern exacerbated by shared hardware structures in computer processors. Recent studies have shown how adversaries can exploit cache timing channel attacks to exfiltrate secret information. To effectively guard computing systems against such attacks, embodiments disclosed herein provide practical defense techniques that are readily deployable and introduce only minimal performance overhead. In this regard, a new protection framework against cache timing channel attacks is provided herein by leveraging commercial off-the-shelf (COTS) hardware support in processor caches, including last level caches (LLC), for cache monitoring and partitioning. This framework applies signal processing techniques on per-domain cache occupancy data to identify suspicious application contexts. Dynamic way partitioning is then used to disband domains that are involved in timing channels
FILED Tuesday, January 28, 2020
APPL NO 16/774826
ART UNIT 2492 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 12/0848 (20130101)
G06F 17/141 (20130101)
G06F 21/75 (20130101) Original (OR) Class
G06F 21/554 (20130101)
G06F 2212/601 (20130101)
G06F 2212/604 (20130101)
G06F 2221/033 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11861429 Strachan et al.
FUNDED BY
National Science Foundation (NSF)
Office of The Director (OD)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Spring, Texas)
INVENTOR(S) John Paul Strachan (Milpitas, California);  Dejan S. Milojicic (Milpitas, California);  Martin Foltin (Ft. Collins, Colombia);  Sai Rahul Chalamalasetti (Milpitas, California);  Amit S. Sharma (Milpitas, California)
ABSTRACT In some examples, a device includes a first processing core comprising a resistive memory array to perform an analog computation, and a digital processing core comprising a digital memory programmable with different values to perform different computations responsive to respective different conditions. The device further includes a controller to selectively apply input data to the first processing core and the digital processing core.
FILED Monday, April 30, 2018
APPL NO 17/049031
ART UNIT 2182 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 17/16 (20130101)

Hybrid Computing Arrangements
G06J 1/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11861739 Meerkov et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Semyon M. Meerkov (Ann Arbor, Michigan);  Pooya Alavian (Ann Arbor, Michigan);  Liang Zhang (Ellington, Connecticut)
ABSTRACT A programmable manufacturing advisor includes an information unit that receives measurements for at least one parameter of each operation of a plurality of operations in the manufacturing process, and an analytics unit that determines a baseline performance metric for the manufacturing process based on the measurements of the at least one parameter. The programmable manufacturing advisor also includes an optimization unit that determines a recommended improvement action by determining a predicted performance metric for the manufacturing process based on an adjusted value of the at least one parameter and comparing the predicted performance metric to the baseline performance metric. The optimization unit also automatically presents the recommended improvement action to the operations manager.
FILED Thursday, October 17, 2019
APPL NO 16/656528
ART UNIT 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/4188 (20130101)
G05B 2219/32128 (20130101)
G05B 2219/33002 (20130101)
G05B 2219/40335 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 7/01 (20230101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0633 (20130101)
G06Q 10/06316 (20130101)
G06Q 10/06393 (20130101)
G06Q 50/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11861834 Kandlikar et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Bired Imaging, Inc. (Rochester, New York)
ASSIGNEE(S) Bired Imaging, Inc. (Rochester, New York)
INVENTOR(S) Satish G. Kandlikar (Rochester, New York);  Donnette Dabydeen (Pittsford, New York);  Lori Medeiros (Pittsford, New York);  Pradyumna Phatak (Pittsford, New York);  Jose Luis Gonzalez Hernandez (Rochester, New York);  Alyssa Owens (East Rochester, New York)
ABSTRACT Processes and techniques are disclosed to identify regions of suspected malignancy and their localization within a body part or organ. These methods rely on the analysis of infrared images to identify thermal abnormalities using image post-processing techniques, numerical modeling, iterative solutions methodology or a digital library. The methods utilize noninvasive, non-radiative and no contact infrared imaging that can be used for breast cancer screening for improved prognosis.
FILED Monday, March 22, 2021
APPL NO 17/208001
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/015 (20130101)
A61B 5/489 (20130101)
A61B 5/4312 (20130101)

Image Data Processing or Generation, in General
G06T 7/0014 (20130101) Original (OR) Class
G06T 7/30 (20170101)
G06T 7/62 (20170101)
G06T 17/00 (20130101)
G06T 2207/10048 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/10116 (20130101)
G06T 2207/10132 (20130101)
G06T 2207/20221 (20130101)
G06T 2207/30068 (20130101)
G06T 2207/30096 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862378 Sullivan et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (, None)
INVENTOR(S) Charles R. Sullivan (West Lebanon, New Hampshire);  Aaron L. F. Stein (West Lebanon, New Hampshire);  Phyo Aung Kyaw (West Lebanon, New Hampshire)
ABSTRACT A resonant coil with integrated capacitance includes at least one separation dielectric layer and a plurality of conductor layers stacked in an alternating manner. Each of the plurality of conductor layers includes a first conductor sublayer and second conductor sublayer having common orientation and a sublayer dielectric layer separating the first and second conductor sublayers. Adjacent conductor layers of the plurality of conductor layers have different orientations.
FILED Friday, July 21, 2017
APPL NO 16/319633
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 27/006 (20130101)
H01F 27/24 (20130101)
H01F 27/323 (20130101)
H01F 27/2804 (20130101) Original (OR) Class
H01F 2027/2809 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862448 Jarrold et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana)
ASSIGNEE(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana)
INVENTOR(S) Martin F. Jarrold (Bloomington, Indiana);  Andrew W. Alexander (Bloomington, Indiana);  Aaron R. Todd (Bloomington, Indiana)
ABSTRACT A CDMS may include an ion source to generate ions from a sample, a mass spectrometer to separate the generated ions as a function of ion mass-to-charge ratio, an electrostatic linear ion trap (ELIT) having a charge detection cylinder disposed between first and second ion mirrors, wherein ions exiting the mass spectrometer are supplied to the ELIT, a charge generator for generating free charges, a field free region between the charge generator and the charge detection cylinder, and a processor configured to control the charge generator, with no ions in the charge detection cylinder, to generate a target number of free charges and cause the target number of free charges to travel across the field-free region and into contact with the charge detection cylinder to deposit the target number of free charges thereon and thereby calibrate or reset the charge detection cylinder to a corresponding target charge level.
FILED Wednesday, January 04, 2023
APPL NO 18/149743
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/0009 (20130101)
H01J 49/022 (20130101)
H01J 49/025 (20130101) Original (OR) Class
H01J 49/4245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862746 Hosein
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Ian D. Hosein (Minoa, New York)
ASSIGNEE(S) SYRACUSE UNIVERSITY (Syracuse, New York)
INVENTOR(S) Ian D. Hosein (Minoa, New York)
ABSTRACT A metallo-dielectric waveguide array used as an encapsulation material for silicon solar cells. The array is produced through light-induced self-writing combined with in situ photochemical synthesis of silver nanoparticles. Each waveguide comprises a cylindrical core consisting of a high refractive index polymer and silver nanoparticles homogeneously dispersed in its medium, all of which are surrounded by a low refractive index common cladding. These waveguide array films are processed directly over a silicon solar cell.
FILED Thursday, April 23, 2020
APPL NO 16/856301
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/186 (20130101)
H01L 31/0481 (20130101)
H01L 31/0543 (20141201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862993 Inoue et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Shuntaro Inoue (North Logan, Utah);  Chakridhar Reddy Teeneti (North Logan, Utah);  Abhilash Kamineni (North Logan, Utah);  Regan A. Zane (Hyde Park, Utah)
ASSIGNEE(S) Utah State University (Logan, Utah)
INVENTOR(S) Shuntaro Inoue (North Logan, Utah);  Chakridhar Reddy Teeneti (North Logan, Utah);  Abhilash Kamineni (North Logan, Utah);  Regan A. Zane (Hyde Park, Utah)
ABSTRACT An apparatus for a high-power reflexive field containment circuit topology for dynamic wireless power transfer systems is disclosed. A wireless power transfer (“WPT”) charging apparatus includes an inverter configured to connect with a direct current (“DC”) source on an input side and one or more WPT charging branches. Each WPT charging branch includes a WPT charging pad circuit with a WPT charging pad connected in series with a first series charging capacitor, a parallel charging capacitor connected in parallel with the WPT charging pad circuit, and a series charging impedance connected in series between an output of the inverter and a connection between the WPT charging pad circuit and the parallel charging capacitor. The series charging impedance includes a second series charging capacitor and/or a series charging inductor.
FILED Friday, July 01, 2022
APPL NO 17/856546
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 53/12 (20190201)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/12 (20160201)
H02J 50/70 (20160201) Original (OR) Class
H02J 50/402 (20200101)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 7/06 (20130101)
H02M 7/537 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11863279 Jamieson et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Trustees of Princeton University (Princeton, New Jersey);  UNIVERSITIES SPACE RESEARCH ASSOCIATION (Columbia, Kentucky)
ASSIGNEE(S) TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey);  UNIVERSITIES SPACE RESEARCH ASSOCIATION (Columbia, Kentucky)
INVENTOR(S) Kyle Jamieson (Princeton, New Jersey);  Minsung Kim (Princeton, New Jersey);  Davide Venturelli (San Francisco, California)
ABSTRACT Systems and methods herein provide for Multi-Input/Multi-Output (MIMO) processing. In one embodiment, a MIMO system comprises a receiver operable to receive a plurality of spatially multiplexed data streams. The system also comprises a processor operable to embed a maximum likelihood (ML) detection algorithm onto a quantum annealer, and to decode the spatially multiplexed data streams via the embedded ML to detect data bits of a plurality of users.
FILED Monday, May 11, 2020
APPL NO 17/606947
ART UNIT 2637 — Optical Communications
CURRENT CPC
Transmission
H04B 7/043 (20130101)
H04B 7/0452 (20130101)
H04B 7/0617 (20130101)
H04B 7/0854 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/06 (20130101)
H04L 1/0054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE49773 Menkhaus et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) NANOPAREIL, LLC (Dakota Dunes, South Dakota)
ASSIGNEE(S) NANOPAREIL, LLC (Comberton, United Kingdom)
INVENTOR(S) Todd J. Menkhaus (Dakota Dunes, South Dakota);  Hao Fong (Dakota Dunes, South Dakota)
ABSTRACT The present invention relates generally to compositions for use in biological and chemical separations, as well as other applications. More specifically, the present invention relates to hybrid felts fabricated from electrospun nanofibers with high permeance and high capacity. Such hybrid felts utilize derivatized cellulose, and at least one non-cellulose-based polymer that may be removed from the felt by subjecting it to moderately elevated temperatures and/or solvents capable of dissolving the non-cellulose-based polymer to leave behind a porous nanofiber felt having more uniform pore sizes and other enhanced properties when compared to single component nanofiber felts.
FILED Tuesday, May 18, 2021
APPL NO 17/323779
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Separation
B01D 15/327 (20130101)
B01D 15/361 (20130101)
B01D 15/3804 (20130101)
B01D 15/3809 (20130101)
B01D 39/1615 (20130101) Original (OR) Class
B01D 39/1623 (20130101)
B01D 39/1676 (20130101)
B01D 2239/025 (20130101)
B01D 2239/0414 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/24 (20130101)
B01J 20/3212 (20130101)
B01J 20/3217 (20130101)
B01J 20/3248 (20130101)
B01J 20/3293 (20130101)
B01J 20/28007 (20130101)
B01J 20/28038 (20130101)

Peptides
C07K 1/22 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/003 (20130101)
D01D 5/0007 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 2/24 (20130101)
D01F 6/44 (20130101)
D01F 6/88 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/48 (20130101)
H01L 24/16 (20130101)
H01L 24/72 (20130101)
H01L 24/73 (20130101)
H01L 24/90 (20130101)
H01L 24/91 (20130101)
H01L 25/50 (20130101)
H01L 25/0652 (20130101)
H01L 2224/16 (20130101)
H01L 2224/72 (20130101)
H01L 2224/81 (20130101)
H01L 2224/90 (20130101)
H01L 2224/131 (20130101)
H01L 2224/131 (20130101)
H01L 2224/9211 (20130101)
H01L 2224/9211 (20130101)
H01L 2224/16227 (20130101)
H01L 2224/73201 (20130101)
H01L 2224/73201 (20130101)
H01L 2224/81138 (20130101)
H01L 2224/81138 (20130101)
H01L 2224/81815 (20130101)
H01L 2224/81815 (20130101)
H01L 2225/06517 (20130101)
H01L 2225/06527 (20130101)
H01L 2225/06531 (20130101)
H01L 2225/06562 (20130101)
H01L 2225/06593 (20130101)
H01L 2924/00 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/00012 (20130101)
H01L 2924/00014 (20130101)
H01L 2924/014 (20130101)
H01L 2924/157 (20130101)
H01L 2924/1579 (20130101)
H01L 2924/3511 (20130101)
H01L 2924/15153 (20130101)
H01L 2924/15787 (20130101)
H01L 2924/15788 (20130101)
H01L 2924/15788 (20130101)
H01L 2924/37001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11857632 Ray et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) INNOSENSE LLC (Torrance, California)
ASSIGNEE(S) INNOSENSE LLC (Torrance, California)
INVENTOR(S) Anamika Ray (Torrance, Canada);  Cheyann Wetteland (Madison, Wisconsin);  Harini Madakashira (Allen, Texas);  Joseph Kessler (Fullerton, California);  Uma Sampathkumaran (Torrance, California)
ABSTRACT A versatile drug delivery system comprised of plant-based nanocellulose can be used for providing high loading and extended release for virtually any drug. This system is made from nanocrystalline cellulose chemically cross-linked to form a hydrogel. This versatile hydrogel-based drug delivery system can be functionalized to support extended release of oral dosing, relieving patient burden and increasing quality of life.
FILED Thursday, October 24, 2019
APPL NO 16/663335
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/38 (20130101) Original (OR) Class
A61K 47/40 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/20 (20130101)
A61L 27/52 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857651 Florez et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma);  UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Fernando Luis Esteban Florez (Moore, Oklahoma);  Sharukh Soli Khajotia (Edmond, Oklahoma);  Adam Justin Rondinone (Knoxville, Tennessee)
ABSTRACT A dental composition comprising doped T1O2 nanoparticles, and a curable resin material, wherein the curable resin material comprises a polymer precursor component, and wherein the dopant may be one or more of, for example, N (nitrogen), Ag (silver), F (fluorine), P (phosphorus), and P04 (phosphate). A method of using the dental composition in a dental application. The dental composition may be antibacterial in the absence of visible light or UV light.
FILED Thursday, December 07, 2017
APPL NO 16/467387
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Dentistry; Apparatus or Methods for Oral or Dental Hygiene
A61C 5/30 (20170201)
A61C 19/063 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 6/17 (20200101)
A61K 6/62 (20200101)
A61K 6/69 (20200101)
A61K 6/816 (20200101)
A61K 6/844 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857950 Khivantsev et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
INVENTOR(S) Konstantin Khivantsev (Richland, Washington);  Libor Kovarik (West Richland, Washington);  Janos Szanyi (Richland, Washington);  Yong Wang (Richland, Washington);  Ja-Hun Kwak (Richland, Washington);  Nicholas R. Jaegers (Richmond, California)
ABSTRACT A material and a method of making hydrothermally stable (catalytic) materials on the basis of theta-alumina support that is thermally and hydrothermally stable up to 1,150 C with metal, mixed metal-, metal-oxide nanoparticles dispersed upon it. Such materials did not lose significant amounts of their catalytic activity at temperature ranges for industrially relevant applications (including hydrocarbon oxidation, nitric oxide reduction, carbon monoxide oxidation) even after hydrothermal aging up to 1,150° C.
FILED Wednesday, November 17, 2021
APPL NO 17/528849
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/04 (20130101) Original (OR) Class
B01J 23/44 (20130101)
B01J 23/464 (20130101)
B01J 35/06 (20130101)
B01J 35/1014 (20130101)
B01J 37/088 (20130101)
B01J 37/0207 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857951 Sadow et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
APPLICANT(S) IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa);  CORNELL UNIVERSITY (Ithaca, New York)
ASSIGNEE(S) IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa);  CORNELL UNIVERSITY (Ithaca, New York)
INVENTOR(S) Aaron D. Sadow (Ames, Iowa);  Wenyu Huang (Ames, Iowa);  Frédéric A. Perras (Ames, Iowa);  Marek Pruski (Ames, Iowa);  Akalanka Tennakoon (Ames, Iowa);  Xun Wu (Ames, Iowa);  Anne M. Lapointe (Ithaca, New York)
ABSTRACT Disclosed herein is a catalyst which comprises a silica core having an outer surface and a mesoporous silica shell having an outer surface and an inner surface with the inner surface being inside the outer surface of said mesoporous silica shell proximate to and surrounding the outer surface of said silica core. Wherein the outer surface of the mesoporous silica shell has openings leading to pores within the mesoporous silica shell which extend toward the outer surface of said silica core. The catalyst also includes catalytically active metal nanoparticles positioned within the pores proximate to said core, wherein the catalytic metal nanoparticles comprise about 0.0001 wt % to about 1.0 wt % of the catalyst. Also disclosed are methods of making the catalyst and using it to carry out a process for catalytically hydrogenolysizing a polyolefinic polymer.
FILED Friday, October 08, 2021
APPL NO 17/497206
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/08 (20130101)
B01J 23/42 (20130101) Original (OR) Class
B01J 35/023 (20130101)
B01J 35/026 (20130101)
B01J 35/1061 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 11/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858075 Gross et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania)
ASSIGNEE(S) Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania)
INVENTOR(S) David M. Gross (Gibsonia, Pennsylvania);  Adana L. Stanish (Cranberry Township, Pennsylvania)
ABSTRACT A method of forming a wick assembly is disclosed including positioning an inner ring in a first wick, positioning the inner ring in a second wick, abutting an end of the first wick with an end of the second wick, positioning an outer ring about a portion of the first wick and a portion of the second wick, positioning a mandrel within the inner ring, positioning a die about the outer ring, and applying a force to the die, wherein the force couples the outer ring, the inner ring, the first wick, and the second wick together to form the wick assembly.
FILED Tuesday, October 25, 2022
APPL NO 18/049526
ART UNIT 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools
B23P 15/26 (20130101) Original (OR) Class
B23P 2700/09 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858202 Smith et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) William Smith (Oakland, California);  Gabriel M. Guss (Manteca, California);  Manyalibo Joseph Matthews (Livermore, California);  Joseph T. McKeown (Pleasanton, California);  John Roehling (Livermore, California)
ABSTRACT The present disclosure relates to an additive manufacturing system for forming a part using a powder material. In one embodiment the system makes use of a primary heat generating subsystem to generate a fusing beam for heating and fusing at least one of select portions of a powder layer, or an entire area of a powder layer, deposited on a build plate. The system also incorporates a beam steering subsystem for steering the fusing beam over the powder layer. A supplemental heating subsystem is used to generate a wide area beam to heat a portion of the powder layer either prior to fusing, along with the fusing operation, or subsequent to fusing of the powder with the fusing beam. The wide area beam has an intensity which is insufficient to fuse the powder, and alters a microstructure of the powder layer as the powder layer is at least one of fused or as it cools, to thus relieve stress in the part.
FILED Tuesday, March 26, 2019
APPL NO 16/365029
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/28 (20210101)
B22F 10/36 (20210101)
B22F 10/38 (20210101)
B22F 10/368 (20210101)
B22F 12/10 (20210101)
B22F 12/41 (20210101)
B22F 12/45 (20210101)
B22F 12/49 (20210101)

Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/60 (20151001)
B23K 26/066 (20151001)
B23K 26/073 (20130101)
B23K 26/342 (20151001)
B23K 26/0608 (20130101)
B23K 26/0626 (20130101)
B23K 26/0643 (20130101)
B23K 26/0648 (20130101)
B23K 26/0884 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/153 (20170801) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858825 Brown et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) X ENERGY, LLC (Rockville, Maryland)
ASSIGNEE(S) X Energy, LLC (Rockville, Maryland)
INVENTOR(S) Daniel Brown (Knoxville, Tennessee);  Nicholas Linneen (Knoxville, Tennessee)
ABSTRACT A solution of acid deficient uranyl nitrate has a formula of UO2(OH)y(NO3)2-y, where y ranges from 0.1 to 0.5. The solution is prepared by placing UxOz in aqueous nitric acid to produce a uranium solution, wherein x is 1 to 3 and z is 2 to 8; placing the uranium solution under a pressure greater than atmospheric pressure in a sealed reaction chamber; and heating the uranium solution to a desired temperature of between 150° C. and 250° C. by applying microwave energy to the uranium solution. The uranium solution is maintained at the desired temperature under a pressure of from 5 atmospheres to 40 atmospheres for a hold time of 15 minutes to 6 hours to produce the desired acid deficient uranyl nitrate.
FILED Wednesday, November 04, 2020
APPL NO 17/088784
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 17/276 (20200101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858826 Young et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Matthias J. Young (Lemont, Illinois);  Jeffrey W. Elam (Lemont, Illinois)
ABSTRACT Further described herein are extensions to the basic concept of LHs as electrode materials, include both new materials for use with LHs and higher order poly-layer hydroxides (PLHs) as well as methods for synthesizing improved LH material such as with conductive supports or through the use of cross-linking. Finally, also described herein are embodiments enabling the use of LHs as flow electrodes as well as the use of 2-d LH materials for surface redox reactions.
FILED Wednesday, May 29, 2019
APPL NO 16/425771
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 7/18 (20130101) Original (OR) Class

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 51/04 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2006/40 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/4604 (20130101)
C02F 1/46109 (20130101)
C02F 2001/46133 (20130101)
C02F 2103/08 (20130101)
C02F 2201/46105 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/04 (20130101)
H01M 4/32 (20130101)
H01M 4/48 (20130101)
H01M 4/0402 (20130101)
H01M 4/485 (20130101)
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 8/188 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858858 Chandrasekaran et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Swetha Chandrasekaran (Dublin, California);  James T. Cahill (Livermore, California);  Wyatt L. Du Frane (Livermore, California);  Joshua D. Kuntz (Livermore, California);  Richard L. Landingham (Livermore, California);  Ryan Lu (Daly City, California);  Marcus A. Worsley (Hayward, California)
ABSTRACT An ink, and products formed from the ink, formulated at least in part from ceramic particles. The ink is formulated so that it can be used in additive manufacturing processes to form three-dimensional printed bodies. The three-dimensional printed bodies can have graded density and can be infiltrated by an infiltration material.
FILED Wednesday, September 09, 2020
APPL NO 17/015403
ART UNIT 1759 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/6263 (20130101)
C04B 35/6264 (20130101)
C04B 35/62218 (20130101) Original (OR) Class
C04B 35/63448 (20130101)
C04B 2235/3813 (20130101)
C04B 2235/3821 (20130101)
C04B 2235/3839 (20130101)
C04B 2235/5436 (20130101)
C04B 2235/5445 (20130101)
C04B 2235/6026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858865 Sant et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Gaurav Sant (Los Angeles, California);  Iman Mehdipour (Los Angeles, California);  Gabriel D. Falzone (Los Angeles, California)
ABSTRACT Provided herein are compositions and methods of carbonation processing for the fabrication of cementitious materials and concrete products. Embodiments include manufacturing processes of a low-carbon concrete product comprising: forming a cementitious slurry including portlandite; shaping the cementitious slurry into a structural component; and exposing the structural component to a CO2 waste stream, thereby enabling manufacture of the low-carbon concrete product.
FILED Wednesday, June 15, 2022
APPL NO 17/840809
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 2/02 (20130101)
C04B 40/0231 (20130101) Original (OR) Class
C04B 40/0263 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859018 Williams et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) TRIAD National Security, LLC. (Los Alamos, New Mexico)
ASSIGNEE(S) TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S) Robert F. Williams (Los Alamos, New Mexico);  David Owen Baumann (Los Alamos, New Mexico);  John Cameron Gordon (Los Alamos, New Mexico)
ABSTRACT The present disclosure provides peptoid-based chelating ligands, corresponding cyclic peptoids, and methods of making thereof. Functional groups may be tailored for high metal binding affinity and selectivity. The side chains of a cyclic peptoid according to the present disclosure may be selected based on, for example, high affinity for actinide or other metal ions, selectivity for actinide or other metal ions, the ability to recover a metal once it is bound to the peptoid, and whether the overall peptoid should be hydrophobic or hydrophilic. Unlike siderophores, peptoid-based chelating ligands of the present disclosure are not readily hydrolyzed under physiological conditions. Therefore, peptoid-based chelating ligands may be, for example, used to treat actinide (e.g., iron and lead) poisoning in vivo. Moreover, peptoid-based chelating ligands of the present disclosure may be used for medical imaging, chelation therapy, drug delivery, and separation technologies, for example.
FILED Friday, January 14, 2022
APPL NO 17/576577
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/64 (20170801)
A61K 49/0056 (20130101)

Peptides
C07K 7/54 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859145 Hegg et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Office of Science (DOE-SC)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan);  Montana State University (Bozeman, Montana);  Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan);  Montana State University (Bozeman, Montana);  Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Eric L. Hegg (East Lansing, Michigan);  Zhaoyang Yuan (Ottawa, Canada);  David B. Hodge (Bozeman, Montana);  Shannon S. Stahl (Madison, Wisconsin);  Bryan D. Bals (Indianapolis, Indiana)
ABSTRACT An improved alkaline pretreatment of biomass is provided that is a single-stage, two oxidant alkaline oxidative pretreatment process. The process uses a homogenous catalyst with at least two oxidants (Hydrogen peroxide and enhanced levels of oxygen) in an alkaline environment to catalytically pretreat lignocellulosic biomass in a single-stage oxidation reaction. The provided single-stage alkaline-oxidative pretreatment improves biomass pretreatment and increase enzymatic digestibility to improve the economic feasibility of production of lignocellulose derived sugars.
FILED Monday, August 29, 2022
APPL NO 17/897566
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/04 (20130101)
B01J 27/055 (20130101)

Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters
C10L 1/02 (20130101) Original (OR) Class
C10L 2200/0484 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859164 Abdullah et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Battelle Memorial Institute (Columbus, Ohio)
ASSIGNEE(S) Battelle Memorial Institute (Columbus, Ohio)
INVENTOR(S) Zia Abdullah (Bexley, Ohio);  Michael L. Dickens (Westerville, Ohio);  Micah Paul McCreery (Baltimore, Ohio);  Randy L. Jones (Delaware, Ohio);  Elvin Ray Beach, III (Columbus, Ohio);  Jon-David S. Sears (Columbus, Ohio);  Erin Suzanne Schultz (Dublin, Ohio);  Stephanie Ann Smith (Columbus, Ohio);  Paul E. George, II (Powell, Ohio)
ABSTRACT Scalable biomaterial-based bioreactors are described. In one embodiment, the bioreactor may comprise perforated plates stacked such that the assembled bioreactor has the necessary manifolds and chambers to transport gas and liquids to a biomaterial contained within the bioreactor, and to remove the reaction products. In another embodiment, single use bioreactors are described. Methods of operating the bioreactors are also described.
FILED Wednesday, April 14, 2021
APPL NO 17/230387
ART UNIT 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/24 (20130101)
C12M 23/34 (20130101)
C12M 23/40 (20130101)
C12M 23/44 (20130101)
C12M 29/04 (20130101) Original (OR) Class
C12M 41/00 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 3/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859266 McCall et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California);  Eck Industries, Inc. (Manitowoc, Wisconsin);  Iowa State University Research Foundation, Inc. (Ames, Iowa);  University of Tennessee Research Foundation (Knoxville, Tennessee);  UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  Eck Industries, Inc. (Manitowoc, Wisconsin);  Iowa State University Research Foundation, Inc. (Ames, Iowa);  University of Tennessee Research Foundation (Knoxville, Tennessee);  UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Scott K. McCall (Livermore, California);  Alexander Baker (Pleasanton, California);  Hunter B. Henderson (Livermore, California);  Tian Li (Pleasanton, California);  Aurelien Perron (Pleasanton, California);  Zachary Cole Sims (Knoxville, Tennessee);  David Weiss (Manitowoc, Wisconsin);  Ryan T. Ott (Ames, Iowa);  Orlando Rios (Knoxville, Tennessee);  Max Neveau (Knoxville, Tennessee)
ABSTRACT A product includes a material having: nickel and at least one rare earth element. The at least one rare earth element is present in the material in a weight percentage in a range of about 2% to about 20% relative to a total weight of the material. A method includes forming a material comprising an alloy of nickel and at least one rare earth element. The at least one rare earth element is present in the material in a weight percentage in a range of about 2% to about 20% relative to a total weight of the material.
FILED Friday, February 25, 2022
APPL NO 17/681424
ART UNIT 1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Alloys
C22C 1/023 (20130101)
C22C 19/055 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859579 Dallmann et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S) Nicholas Dallmann (Los Alamos, New Mexico);  Ian Shelburne (Los Alamos, New Mexico);  Kavitha Chintam (Los Alamos, New Mexico);  Malakai Coblentz (Los Alamos, New Mexico);  David Hemsing (Los Alamos, New Mexico);  Joseph Lichthardt (Los Alamos, New Mexico);  Bryce Tappan (Los Alamos, New Mexico);  Mahlon S. Wilson (Los Alamos, New Mexico)
ABSTRACT A system for multiple burns from a solid fuel rocket motor may extinguish rocket fuel after the rocket has been ignited. The motor may be extinguished via rapid decompression of the combustion chamber. The fuel may then be reignited by a suitable igniter, and the process of extinguishing and reigniting may be repeated, enabling multi-burn maneuvers. A decompressive extinguishing plug nozzle may extinguish solid rocket fuel after the rocket has been ignited and/or keep a rocket in a disarmed (zero thrust) state until the rocket is to be armed. The nozzle may include a plug that mostly impedes the opening of the nozzle and an outer cowl that is movable to rapidly decompress the combustion chamber. This rapid decompression extinguishes the solid rocket fuel. In some aspects, the fuel can be reignited and extinguished multiple times.
FILED Wednesday, July 29, 2020
APPL NO 16/941642
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Jet-propulsion Plants
F02K 9/28 (20130101)
F02K 9/34 (20130101)
F02K 9/84 (20130101)
F02K 9/86 (20130101) Original (OR) Class
F02K 9/763 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2240/1281 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859863 McGrail et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Bernard P. McGrail (Pasco, Washington);  Jeromy W. J. Jenks (Hines, Oregon);  Radha K. Motkuri (Richland, Washington)
ABSTRACT Methods, systems and devices for managing humidity within an HVAC system including a nanostructured desiccant porous material configured to adsorb water from an inlet stream at a first air pressure and to release water from that material when subjected to a second air pressure when the second air pressure is lower than the first air pressure is located within a particular location so as to allow for the passage of wet air over the materials and allow adsorption of the water on to the material. When coupled with a vacuum pump water can be collected and released from the materials and the system, regenerating the material for future use and removing water from a stream at a significantly lower cost than existing processes.
FILED Friday, August 14, 2020
APPL NO 16/993699
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 3/153 (20130101)
F24F 3/1411 (20130101) Original (OR) Class
F24F 2003/1435 (20130101)
F24F 2003/1458 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860100 Demos et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
APPLICANT(S) UNIVERSITY OF ROCHESTER (Rochester, New York)
ASSIGNEE(S) UNIVERSITY OF ROCHESTER (Rochester, New York)
INVENTOR(S) Stavros G. Demos (Pittsford, New York);  Chi Huang (Foster City, California)
ABSTRACT Microscopy with Ultraviolet Surface Excitation (MUSE) for use in the classroom to enhance life sciences education and curricula, or for other applications, including without limtiation the operating room, other medical environments, research environments, and low resource environments. MUSE's suitability is based on multiple key factors including its simplicity of use, the incorporation of inexpensive hardware including LED illumination, and very basic tissue preparation. The ultraviolet excitation acts as passive optical sectioning confining the generated fluorescence signal to only a few micrometers below the tissue surface thus eliminating the out of focus signals. This facilitates image capture of tissue microstructure and organization from specimens at the intact or sliced surface arising from varying fluorophore concentration within the different cellular compartments. Although just the tissue auto fluorescence maybe used, image quality is enhanced with brief application of nontoxic fluorescent dyes to selectively highlight cellular compartments. Sample preparation is safe, efficient and familiar to students with basic chemistry or biology lab experience. Mixed-dye powders may be used to simplify translation of this method for educational, medical, research, low resource, and other settings.
FILED Friday, January 25, 2019
APPL NO 16/964831
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/30 (20130101)
G01N 21/6458 (20130101) Original (OR) Class
G01N 2001/302 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860773 Roberts
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Micron Technology, Inc. (Boise, Idaho)
ASSIGNEE(S) Micron Technology, Inc. (Boise, Idaho)
INVENTOR(S) David A. Roberts (Wellesley, Massachusetts)
ABSTRACT Systems, apparatuses, and methods related to memory access statistics monitoring are described. A host is configured to map pages of memory for applications to a number of memory devices coupled thereto. A first memory device comprises a monitoring component configured to monitor access statistics of pages of memory mapped to the first memory device. A second memory device does not include a monitoring component capable of monitoring access statistics of pages of memory mapped thereto. The host is configured to map a portion of pages of memory for an application to the first memory device in order to obtain access statistics corresponding to the portion of pages of memory upon execution of the application despite there being space available on the second memory device and adjust mappings of the pages of memory for the application based on the obtained access statistics corresponding to the portion of pages.
FILED Thursday, February 03, 2022
APPL NO 17/591729
ART UNIT 2135 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0238 (20130101) Original (OR) Class
G06F 12/0292 (20130101)
G06F 12/0882 (20130101)
G06F 13/1621 (20130101)
G06F 13/1689 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860815 Tang et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S) Brookhaven Science Associates, LLC (Upton, New York)
ASSIGNEE(S) Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S) Shaochun Tang (New York, New York);  Michael Begel (New York, New York);  Hucheng Chen (New York, New York);  Helio Takai (New York, New York);  Francesco Lanni (Segny, France)
ABSTRACT A reconfigurable computing platform includes a reconfigurable computing device, electro-optical transceiver, and first voltage converter disposed on a multilayer board. The electro-optical transceiver converts an optical signal at least one of to and from an electrical signal, and the electrical signal is operatively coupled to the reconfigurable computing device. The electro-optical transceiver is disposed in proximity to the reconfigurable computing device, and the first voltage converter is operatively coupled to a common voltage distributed around a periphery of the multilayer board. The first voltage converter converts the common voltage to a first operating voltage, and the first voltage converter is disposed in proximity to the reconfigurable computing device. The first operating voltage is provided to the reconfigurable computing device as a first power source. A reconfigurable computing system includes a plurality of reconfigurable computing platforms operatively coupled together using an optical signal. A corresponding method of providing a reconfigurable computing platform is also disclosed.
FILED Friday, October 04, 2019
APPL NO 17/281731
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Electric Digital Data Processing
G06F 1/12 (20130101)
G06F 1/26 (20130101)
G06F 1/189 (20130101)
G06F 15/7867 (20130101) Original (OR) Class

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/0251 (20130101)
H05K 2201/10121 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862449 Cahill et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) John F. Cahill (Knoxville, Tennessee);  Vilmos Kertesz (Oak Ridge, Tennessee);  Scott T. Retterer (Knoxville, Tennessee)
ABSTRACT A system for sampling a liquid includes a sample fluid conduit including a membrane having pores. The membrane prevents the passage of the sample liquid through the pores at a first pressure of the sample liquid in the sample fluid conduit. A surface sampling capture probe has a distal end. The capture probe includes a solvent supply conduit and a solvent exhaust conduit. A solvent composition flowing at the distal end of the capture probe establishes a liquid junction with the membrane and establishes a second pressure within the liquid junction at the membrane. The second pressure is lower than the first pressure. Sample liquid will be drawn through the pores of the membrane by the second pressure at the liquid junction. A method for sampling a liquid and for performing chemical analysis on a liquid are also disclosed.
FILED Monday, August 15, 2022
APPL NO 17/888397
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/10 (20130101)
G01N 30/7233 (20130101)
G01N 35/1095 (20130101)
G01N 2001/028 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/0454 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862758 Cherepy et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  Current Lighting Solutiosn, LLC (Cleveland, Ohio)
INVENTOR(S) Nerine Cherepy (Piedmont, California);  Ross Allen Osborne (Livermore, California);  Stephen A. Payne (Castro Valley, California);  Zachary Seeley (Livermore, California);  Alok Srivastava (Niskayuna, New York);  William Winder Beers (Chesterland, Ohio);  William Erwin Cohen (Solon, Ohio)
ABSTRACT The present disclosure relates to a lighting component which may comprise a light emitting diode (LED) or laser diode (LD) for generating at least one of blue light or ultraviolet light. A fluoride phosphor matrix may be included, which may be consolidated into a phosphor ceramic structure including at least one of a transparent fluoride ceramic structure or a translucent fluoride ceramic structure, and positioned adjacent to the LED or LD. The phosphor ceramic structure generates at least one of red or orange light when irradiated by the light emitted from the LED or LD. The phosphor ceramic structure exhibits reduced thermal quenching relative to a fluoride particulate structure irradiated by the LED or LD.
FILED Tuesday, November 26, 2019
APPL NO 16/696472
ART UNIT 2875 — Optics
CURRENT CPC
Non-electric Light Sources Using Luminescence; Light Sources Using Electrochemiluminescence; Light Sources Using Charges of Combustible Material; Light Sources Using Semiconductor Devices as Light-generating Elements; Light Sources Not Otherwise Provided for
F21K 9/64 (20160801)
F21K 9/90 (20130101)

Indexing Scheme Associated With Subclasses F21K, F21L, F21S and F21V, Relating to the Form or the Kind of the Light Sources or of the Colour of the Light Emitted
F21Y 2115/10 (20160801)
F21Y 2115/30 (20160801)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 33/0095 (20130101)
H01L 33/504 (20130101) Original (OR) Class
H01L 33/641 (20130101)
H01L 2933/0041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862779 Ernst et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Cummins Inc. (Columbus, Indiana)
ASSIGNEE(S) Cummins Inc. (Columbus, Indiana)
INVENTOR(S) Timothy C. Ernst (Columbus, Indiana);  Jonathan A. Dickson (Columbus, Indiana);  Manik Narula (Columbus, Indiana)
ABSTRACT A cooling system for an electrified vehicle includes a first cooling loop for circulating coolant for cooling at least one of power electronics and a motor/generator of the vehicle. The first coolant loop includes a heat exchanger for exchanging heat with the coolant in the first cooling loop. A second cooling loop is provided for circulating coolant for cooling a battery of the vehicle. The second cooling loop includes a coolant chiller connected to a refrigeration system of the vehicle for exchanging heat in the coolant received from the battery with the refrigeration system of the vehicle.
FILED Wednesday, April 07, 2021
APPL NO 17/224523
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles
B60H 1/00278 (20130101)
B60H 1/00392 (20130101)

Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 58/26 (20190201)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/66 (20150401) Original (OR) Class
H01M 10/613 (20150401)
H01M 10/625 (20150401)
H01M 10/635 (20150401)
H01M 10/6568 (20150401)
H01M 2220/20 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/20263 (20130101)
H05K 7/20272 (20130101)
H05K 7/20927 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862783 Mane et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Anil U. Mane (Naperville, Illinois);  Jeffrey W. Elam (Elmhurst, Illinois);  Joong Sun Park (Woodridge, Illinois);  Jason R. Croy (Bolingbrook, Illinois)
ABSTRACT The fabrication of robust interfaces between transition metal oxides and non-aqueous electrolytes is one of the great challenges of lithium ion batteries. Atomic layer deposition (ALD) of aluminum tungsten fluoride (AlWxFy) improves the electrochemical stability of LiCoO2. AlWxFy thin films were deposited by combining trimethylaluminum and tungsten hexafluoride. in-situ quartz crystal microbalance and transmission electron microscopy studies show that the films grow in a layer-by-layer fashion and are amorphous nature. Ultrathin AlWxFy coatings (<10 Å) on LiCoO2 significantly enhance stability relative to bare LiCoO2 when cycled to 4.4 V. The coated LiCoO2 exhibited superior rate capability (up to 400 mA/g) and discharge capacities at a current of 400 mA/g were 51% and 92% of the first cycle capacities for the bare and AlWxFy coated materials. These results open new possibilities for designing ultrathin and electrochemically robust coatings of metal fluorides via ALD to enhance the stability of Li-ion electrodes.
FILED Tuesday, August 17, 2021
APPL NO 17/404055
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/30 (20130101)
C23C 16/45531 (20130101)
C23C 16/45555 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/366 (20130101)
H01M 4/0421 (20130101) Original (OR) Class
H01M 4/505 (20130101)
H01M 4/628 (20130101)
H01M 4/1391 (20130101)
H01M 10/0525 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862794 Xiao et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Jie Xiao (Richland, Washington);  Yujing Bi (Richland, Washington)
ABSTRACT Methods for synthesizing single crystalline Ni-rich cathode materials are disclosed. The Ni-rich cathode material may have a formula LiNiXMnyMzCo1-x-y-zO2, where M represents one or more dopant metals, x≥0.6, 0.01≤y<0.2, 0≤z≤0.05, and x+y+z≤1.0. The methods are cost-effective, and include methods for solid-state, molten-salt, and flash-sintering syntheses.
FILED Wednesday, November 18, 2020
APPL NO 16/951868
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 53/50 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/52 (20130101)
C01P 2002/72 (20130101)
C01P 2002/85 (20130101)
C01P 2002/90 (20130101)
C01P 2004/03 (20130101)
C01P 2004/04 (20130101)
C01P 2004/61 (20130101)
C01P 2004/62 (20130101)
C01P 2006/40 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/08 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/505 (20130101)
H01M 4/525 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 2004/021 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11864357 Zhou et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) TOYOTA MOTOR ENGINEERING and MANUFACTURING NORTH AMERICA, INC. (Plano, Texas);  University of Colorado Boulder (Boulder, Colorado)
ASSIGNEE(S) Toyota Motor Engineering and Manufacturing North America, Inc. (Plano, Texas);  University of Colorado Boulder (Boulder, Colorado)
INVENTOR(S) Feng Zhou (Ann Arbor, Michigan);  Yuqing Zhou (Ann Arbor, Michigan);  Ercan Mehmet Dede (Ann Arbor, Michigan);  Robert Erickson (Boulder, Colorado);  Dragan Maksimovic (Boulder, Colorado);  Vivek Sankaranarayanan (Boulder, Colorado);  Yucheng Gao (Boulder, Colorado)
ABSTRACT A double-sided cold plate includes a manifold comprising openings extending from a first surface of the manifold through the manifold to a second surface of the manifold forming recesses within the manifold and an inlet channel and an outlet channel fluidly coupled to the recesses within the manifold, a plurality of first heat sinks coupled to the first surface of the manifold enclosing the openings on the first surface, and a plurality of second heat sinks positioned adjacent each other along a length of the manifold and coupled to the second surface of the manifold, enclosing the openings on the second surface, a width of the plurality of second heat sinks is greater than a width of the manifold thereby forming an overhanging portion on each lengthwise side of the manifold, the overhanging portion configured to mechanically support a plurality of electrical components positioned around a perimeter of the manifold.
FILED Tuesday, May 25, 2021
APPL NO 17/329727
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/209 (20130101)
H05K 7/20254 (20130101)
H05K 7/20509 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11864465 Lagally et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin);  University of Hamburg (Hamburg, Germany)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Max G. Lagally (Madison, Wisconsin);  Abhishek Bhat (Fremont, California);  Frank Steele Flack (Madison, Wisconsin);  Shelley Ann Scott (Madison, Wisconsin);  Robert H. Blick (Hamburg, Germany)
ABSTRACT Piezoelectrically actuated devices constructed from thin semiconductor membranes bonded directly to piezoelectric substrates are provided. Methods for fabricating these devices are also provided. The bonding of the semiconductor to the piezoelectric material does not require the use of any intermediate layers, such as bonding agents.
FILED Friday, May 22, 2020
APPL NO 16/881305
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Electric solid-state devices not otherwise provided for
H10N 30/072 (20230201) Original (OR) Class
H10N 30/206 (20230201)
H10N 30/802 (20230201)
H10N 30/875 (20230201)
H10N 30/8554 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11857813 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Aeronautics and Space Administration (NASA)
National Space Biomedical Research Institute (NSBRI)
APPLICANT(S) University of Washington (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Yak-Nam Wang (Seattle, Washington);  Michael R. Bailey (Seattle, Washington);  Tatiana D. Khokhlova (Seattle, Washington);  Wayne Kreider (Seattle, Washington);  Adam D. Maxwell (Seattle, Washington);  George R. Schade (Seattle, Washington);  Vera A. Khokhlova (Seattle, Washington)
ABSTRACT High intensity focused ultrasound systems for treating tissue are disclosed herein. A system of treating tissue in a patient in accordance with an embodiment of the present technology can include, for example, an ultrasound source having a focal region and configured to deliver high intensity focused ultrasound energy to a target site in tissue of the patient. The system can further include a controller operably coupled to the ultrasound source. The controller comprises a pulsing protocol for delivering the high intensity focused ultrasound energy with the ultrasound source to the target site. The controller is configured to cause the ultrasound source to pulse high intensity focused ultrasound waves to lyse cells in a volume of the tissue of the subject while preserving an extracellular matrix in the volume of the tissue exposed to the high intensity focused ultrasound waves.
FILED Monday, July 13, 2020
APPL NO 16/927860
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/02 (20130101) Original (OR) Class
A61N 2007/0004 (20130101)
A61N 2007/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859272 Scannapieco et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) David S. Scannapieco (Cleveland, Ohio);  David L. Ellis (Cleveland, Ohio)
ABSTRACT In situ alloying of elemental Cu, Cr, and Nb powder using laser melting to form a Cu—Cr2Nb alloy. The elemental powders are initially mixed to form a homogeneous mixture, which mixture is then subjected to laser radiation to melt the mixture. In the melt, the Cr and Nb react to form Cr2Nb, which when cooled form precipitates that are dispersed in a nearly pure Cu matrix to thus dispersion strengthen the material. The methods can be used to additively manufacture a 3D component of Cu—Cr2Nb alloy using a selective laser melting machine.
FILED Tuesday, April 20, 2021
APPL NO 17/235395
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/28 (20210101)

Alloys
C22C 9/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859315 Lizcano et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Maricela Lizcano (Cleveland, Ohio);  Diana Santiago-Dejesus (Cleveland, Ohio)
ABSTRACT A method of preparing hexagonal boron nitride (h-BN) fibers includes mixing polyvinylpyrrolidone (PVP) and boron oxide (B2O3) to form a polymer precursor or mixing PVP and ammonia borane (BH3NH3) to form the polymer precursor. The method includes forcespinning the polymer precursor to form fibers of the polymer precursor, curing the fibers to form polymer fibers, and pyrolyzing the polymer fibers to form the h-BN fibers.
FILED Monday, January 24, 2022
APPL NO 17/582329
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 41/042 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/6229 (20130101)
C04B 41/0045 (20130101)
C04B 2235/658 (20130101)
C04B 2235/661 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/18 (20130101) Original (OR) Class

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 9/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11859705 Hofmann et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Douglas C. Hofmann (Altadena, California);  Robert P. Dillon (Costa Mesa, California);  Scott N. Roberts (Altadena, California)
ABSTRACT Harmonic drives are used widely in robotics as a method for achieving high gear reductions and for driving force transmissions. The harmonic drive is made a three components: a wave generator, a flexspline, and a circular spline. Embodiments described flexsplines for a metal strain wave gearing. The cup of the flexspline is free from sharp edges and with a rounded bottom with a curvature maximized based on the geometry of the flexspline. Compared to a steel flexspline, implementations of flexsplines will have the same outer diameter, the same number of teeth and profile, the same input shaft/base, the same wall thickness near the teeth, but comprise a rounded bottom where the input shaft/base transitions to the straight wall of the flexspline, providing improved performance of BMG flexsplines by reducing low cycle fatigue failures due to stress concentrations.
FILED Wednesday, February 26, 2020
APPL NO 16/802267
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Gearing
F16H 49/001 (20130101) Original (OR) Class
F16H 2049/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860160 Zenhausern et al.
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
INVENTOR(S) Frederic Zenhausern (Chandler, Arizona);  Peng Chen (Chandler, Arizona);  Jian Gu (Chandler, Arizona);  Jerome Lacombe (Chandler, Arizona)
ABSTRACT Provided are vertical flow detection devices and related methods. The devices may comprise a membrane having a first surface and a second surface with a plurality of porous structures extending between the first and second surfaces to form fluid conduits from a first fluid chamber formed by the first surface and a second fluid chamber formed by the second fluid surface. A capture agent is immobilized on and/or in the membrane. A rigid porous membrane support mechanically supports the membrane and to provide a relatively uniform flow across the membrane. Various gaskets or holder elements are positioned around an outer edge of the membrane to prevent fluid leakage around the membrane. A fluid pump is configured to force a fluid sample flow in a direction from the first fluid chamber to the second fluid chamber.
FILED Friday, March 29, 2019
APPL NO 17/040417
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2200/0689 (20130101)
B01L 2300/12 (20130101)
B01L 2300/0877 (20130101)
B01L 2400/0475 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54391 (20210801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862854 Hassan et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Asif Hassan (Miami, Florida);  Elias Alwan (Miami, Florida);  Daniela Rodica Radu (Miami, Florida);  Cheng-Yu Lai (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Asif Hassan (Miami, Florida);  Elias Alwan (Miami, Florida);  Daniela Rodica Radu (Miami, Florida);  Cheng-Yu Lai (Miami, Florida)
ABSTRACT Antenna arrays, antenna elements for said arrays, and methods of fabricating and using the same are provided. Antenna arrays can be operated at multiple frequencies, such as at two different frequencies for Radio Detection And Ranging (RADAR) communication and for imaging applications. Each antenna element can include a driven patch that is excited directly and a parasitic patch that is excited by the driven patch.
FILED Friday, May 12, 2023
APPL NO 18/316680
ART UNIT 2845 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/247 (20130101)
H01Q 9/0407 (20130101)
H01Q 19/005 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11864006 Barsoum et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Constellation Designs, LLC (Wayne, Pennsylvania)
ASSIGNEE(S) Constellation Designs, LLC (Wayne, Pennsylvania)
INVENTOR(S) Maged F. Barsoum (San Jose, California);  Christopher R. Jones (Pacific Palisades, California)
ABSTRACT Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation.
FILED Tuesday, July 27, 2021
APPL NO 17/386179
ART UNIT 2632 — Digital Communications
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 13/255 (20130101)
H03M 13/6325 (20130101)

Transmission
H04B 15/00 (20130101)
H04B 17/336 (20150115)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0003 (20130101)
H04L 1/0009 (20130101)
H04L 27/3405 (20130101)
H04L 27/3483 (20130101)
H04L 27/3809 (20130101)

Wireless Communication Networks
H04W 24/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11864007 Barsoum et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Constellation Designs, LLC (Wayne, Pennsylvania)
ASSIGNEE(S) Constellation Designs, LLC (Wayne, Pennsylvania)
INVENTOR(S) Maged F. Barsoum (San Jose, California);  Christopher R. Jones (Pacific Palisades, California)
ABSTRACT Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation.
FILED Thursday, May 26, 2022
APPL NO 17/804306
ART UNIT 2632 — Digital Communications
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 13/255 (20130101)
H03M 13/6325 (20130101)

Transmission
H04B 15/00 (20130101)
H04B 17/336 (20150115)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0003 (20130101)
H04L 1/0009 (20130101)
H04L 27/3405 (20130101)
H04L 27/3483 (20130101)
H04L 27/3809 (20130101)

Wireless Communication Networks
H04W 24/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11864472 Greer et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Harold Frank Greer (Pasadena, California);  Andrew D. Beyer (Pasadena, California);  Matthew D. Shaw (Pasadena, California);  Daniel P. Cunnane (Pasadena, California)
ABSTRACT A method for etching a surface including obtaining a structure comprising a plurality of nanowires on or above a substrate and a dielectric layer on or above the nanowires, wherein the dielectric layer comprises protrusions formed by the underlying nanowires; reacting a surface of the dielectric layer with a reactant, comprising a gas or a plasma, to form a reactive layer on the dielectric layer, wherein the reactive layer comprises a chemical compound including the reactant and elements of the dielectric layer and the reactive layer comprises sidewalls defined by the protrusions; and selectively etching the reactive layer, wherein the etching etches the protrusions laterally through the sidewalls so as to planarize the surface and remove or shrink the protrusions.
FILED Monday, July 12, 2021
APPL NO 17/373619
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Electric solid-state devices not otherwise provided for
H10N 60/01 (20230201) Original (OR) Class
H10N 60/83 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11858636 Smith et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Spencer Smith (Washington, District of Columbia);  Riely Brande (Washington, District of Columbia);  Nolan Richerson (Washington, District of Columbia);  Benjamin Crutchfield (Washington, District of Columbia);  Christian Breviario (Washington, District of Columbia);  Ronald Adrezin (East Lyme, Connecticut);  Michael Plumley (Washington, District of Columbia);  Marion Lewandowski (Old Saybrook, Connecticut)
ABSTRACT A rescue basket having the capacity to safely hold two full-sized individuals increases the efficiency and effectiveness of helicopter water rescue and recovery operations. The rescue basket includes an open end, which affords an additional option for loading passengers, along with a door mechanism that can at least partially close off the open end for passenger safety. The rescue basket includes a flotation system that maintains the basket at a desired flotation level when completely immersed in water, along with sufficient reserve buoyancy to safely maintain the passengers above water when loaded. Methods of performing a water rescue utilizing the present rescue basket on board of a helicopter are also provided.
FILED Thursday, March 28, 2019
APPL NO 16/368013
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects
B63C 9/01 (20130101)
B63C 9/26 (20130101)
B63C 2009/265 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 1/22 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860333 Remer
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) James Henry Remer (Waterford Works, New Jersey)
ABSTRACT Examples are directed toward systems and methods relating to security screening. For example, a screening system includes a sensor array to sense a gravitational field caused by an item, and a conveyor to convey the item through sensing positions for scanning by the sensor array. A controller acquires weight measurement information from sensor elements, and gravitational measurement information from the sensor array. The conveyor incrementally advances the item through additional sensing positions to acquire weight measurement information and gravitational measurement information. The controller performs tomographic reconstruction to generate a tomographic image of the item, using a generated weight map as a static weight input vector and using a generated mass map as a static mass input vector for the tomographic reconstruction.
FILED Friday, May 05, 2023
APPL NO 18/143806
ART UNIT 2884 — Optics
CURRENT CPC
Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags
G01V 5/005 (20130101) Original (OR) Class
G01V 7/04 (20130101)

Image Data Processing or Generation, in General
G06T 11/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862426 Wells et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-ST)
APPLICANT(S) Teledyne FLIR Detection, Inc. (Stillwater, Oklahoma)
ASSIGNEE(S) Teledyne FLIR Detection, Inc. (Stillwater, Oklahoma)
INVENTOR(S) James Mitchell Wells (West Lafayette, Indiana);  Douglas K. Martins (Lafayette, Indiana);  Mark Gildersleeve (West Lafayette, Indiana);  Rakesh Patel (West Lafayette, Indiana)
ABSTRACT The present disclosure provides electron source devices, electron source assemblies, and/or methods for generating electrons. The generated electrons can be used to facilitate spectroscopy, such as mass spectrometry, including mass selection or ion mobility.
FILED Friday, June 29, 2018
APPL NO 16/024215
ART UNIT 2875 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 3/025 (20130101) Original (OR) Class
H01J 2237/063 (20130101)
H01J 2237/06366 (20130101)
H01J 2237/06375 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11863994 Lim et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Jason Lim (Alexandria, Virginia);  Daniel Boyd (Arlington, Virginia);  Chang Ellison (Arlington, Virginia);  William Washington (North Potomac, Maryland)
ABSTRACT In an example, a provider system receives from a client device a request for client sign-on access. The provider system sends to the client device a request for identification information of the client. The provider system receives client information associated with a first mobile identification credential (MIC) which the client device received from an authorizing party system (APS), the client having consented to release the client information to the provider system, and the client information having been verified by the APS. The provider system uses the verified client information associated with the first MIC to verify or not verify the identity of the client. The provider system verifies the identity of the client before granting the client the request for client sign-on access.
FILED Thursday, March 02, 2023
APPL NO 18/116503
ART UNIT 2876 — Optics
CURRENT CPC
Wireless Communication Networks
H04W 12/06 (20130101)
H04W 12/08 (20130101)
H04W 12/71 (20210101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11857318 Hsiai et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Tzung K. Hsiai (Santa Monica, California);  Yu-Chong Tai (Pasadena, California);  Rene R. Sevag Packard (Los Angeles, California);  Yuan Luo (Pasadena, California);  Parinaz Abiri (Los Angeles, California);  Jianguo Ma (Shangdong Province, China PRC)
ABSTRACT The present invention provides devices for characterizing regions of tissue and methods for using the same. The devices are capable of locating, identifying, and characterizing tissue regions of interest in vivo. In one embodiment, the devices are ultrasound-guided. In one embodiment, the devices use characterize regions of tissue using electrical impedance spectroscopy (EIS) sensors. In one aspect, the devices are useful in predicting plaque rupture, such as by determining the level of oxidized low density lipoprotein (oxLDL) and macrophage/foam cells present in an atheroma. In one aspect, the devices are useful in identifying metabolically active atherosclerotic lesions that are angiographically invisible.
FILED Tuesday, May 09, 2017
APPL NO 16/099742
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/026 (20130101)
A61B 5/0205 (20130101)
A61B 5/0215 (20130101)
A61B 5/0537 (20130101)
A61B 5/0538 (20130101)
A61B 5/1473 (20130101) Original (OR) Class
A61B 5/02007 (20130101)
A61B 5/6853 (20130101)
A61B 5/7275 (20130101)
A61B 8/12 (20130101)
A61B 8/445 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 2025/1079 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/026 (20130101)
G01N 29/00 (20130101)
G01N 29/06 (20130101)
G01N 29/0654 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11857550 Chen et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as Represented By the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Beibei Chen (Sewickley, Pennsylvania);  Rama K. Mallampalli (Sewickley, Pennsylvania)
ABSTRACT A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: wherein X is a divalent linking moiety; and R1-R10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R3 or R8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen.
FILED Thursday, November 19, 2020
APPL NO 16/953201
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/137 (20130101)
A61K 31/341 (20130101)
A61K 31/381 (20130101)
A61K 31/402 (20130101)
A61K 31/427 (20130101)
A61K 31/435 (20130101)
A61K 31/444 (20130101)
A61K 31/506 (20130101) Original (OR) Class
A61K 31/4155 (20130101)
A61K 31/4178 (20130101)
A61K 31/4418 (20130101)
A61K 31/5375 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)
A61P 11/06 (20180101)
A61P 19/00 (20180101)
A61P 25/00 (20180101)
A61P 35/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 211/01 (20130101)
C07C 211/53 (20130101)
C07C 229/38 (20130101)

Heterocyclic Compounds
C07D 207/06 (20130101)
C07D 211/14 (20130101)
C07D 213/06 (20130101)
C07D 213/36 (20130101)
C07D 213/38 (20130101)
C07D 231/12 (20130101)
C07D 233/61 (20130101)
C07D 233/64 (20130101)
C07D 239/26 (20130101)
C07D 265/30 (20130101)
C07D 277/28 (20130101)
C07D 295/135 (20130101)
C07D 401/12 (20130101)
C07D 403/12 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US D1009804 Duvall et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia);  University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) United States Goverment As Represented By The Department Of Veterans Affairs (Washington, District of Columbia);  University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Jonathan Aaron Duvall (Pittsburgh, Pennsylvania);  Rory A. Cooper (Pittsburgh, Pennsylvania);  Garrett G. Grindle (Pittsburgh, Pennsylvania);  Joshua David Kanode (Pittsburgh, Pennsylvania);  Douglas A. Hilliard (Pittsburgh, Pennsylvania)
ABSTRACT
FILED Thursday, June 04, 2020
APPL NO 29/736993
ART UNIT 2912 — Design
CURRENT CPC
Equipment for production, distribution, or transformation of energy
D13/160
VIEW PATENT @ USPTO:  Full Text   PDF 
US D1010123 Kooner et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) The Board of Regents of The University of Texas System (Austin, Texas);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Karanjit S. Kooner (Plano, Texas);  Michael A. Mong (Grapevine, Texas);  Ghadeer Al-Humimat (Dallas, Texas);  Jacob A. Awkal (Plano, Texas);  Hebah G. Abdallah (Carrollton, Texas);  Nguyen L. Le (Richardson, Texas);  Jamasp Azarnoosh (Dallas, Texas);  Peter Dirk Jan Reyntjens (Richardon, Texas);  Jeremy L. Warren (El Paso, Texas)
ABSTRACT
FILED Friday, July 22, 2022
APPL NO 29/847320
ART UNIT 2916 — Design
CURRENT CPC
Medical and laboratory equipment
D24/143
VIEW PATENT @ USPTO:  Full Text   PDF 

General Services Administration (GSA) 

US 11863678 Wilson et al.
FUNDED BY
General Services Administration (GSA)
APPLICANT(S) Tenet 3, LLC (Dayton, Ohio)
ASSIGNEE(S) Tenet 3, LLC (Dayton, Ohio)
INVENTOR(S) Kelce S. Wilson (Murphy, Texas);  Jeff A. Hughes (Dayton, Ohio);  Tyler J. Moody (Fairborn, Ohio);  Derek E. Doran (Hilliard, Ohio);  Gary R. Tuttle (Middletown, Ohio);  Joel B. Rieman (Xenia, Ohio)
ABSTRACT A permissioned blockchain, using off-chain storage, provides advantages over blockchains that rely on consensus and/or store information within the blockchain. Advantages include enhanced viability, compactness, and the ability to register material with distribution limitations (e.g., military classified). Examples create an immutable public record of data signatures that confirm when data is intact, without distributing the data itself, so that widespread availability of the blockchain (beyond those privileged to see the data) advantageously increases the size of the community that is able to detect spoofing or forgery attempts. A permissioning entity limits submissions to manage blockchain growth, foreclosing problematic material that may risk long-term viability. Examples render blockchain operations resistant to advanced persistent threats (APTs), leverage digital signatures as additional trust elements for high-risk data, link records to track pedigree and enable identification of superseded (obsolete) data, and leverage out-of-band date proof to enable independent verification of integrity and no-later-than data-of-existence.
FILED Thursday, December 31, 2020
APPL NO 17/139633
ART UNIT 2431 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/64 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/50 (20220501)
H04L 9/3218 (20130101) Original (OR) Class
H04L 9/3239 (20130101)
H04L 9/3247 (20130101)
H04L 63/1483 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11863679 Wilson et al.
FUNDED BY
General Services Administration (GSA)
APPLICANT(S) Tenet 3, LLC (Dayton, Ohio)
ASSIGNEE(S) Tenet 3, LLC (Dayton, Ohio)
INVENTOR(S) Kelce S. Wilson (Murphy, Texas);  Jeff A. Hughes (Dayton, Ohio);  Tyler J. Moody (Fairborn, Ohio);  Derek E. Doran (Hilliard, Ohio);  Gary R. Tuttle (Middletown, Ohio);  Joel B. Rieman (Xenia, Ohio)
ABSTRACT A permissioned blockchain, using off-chain storage, provides advantages over blockchains that rely on consensus and/or store information within the blockchain. Advantages include enhanced viability, compactness, and the ability to register material with distribution limitations (e.g., military classified). Examples create an immutable public record of data signatures that confirm when data is intact, without distributing the data itself, so that widespread availability of the blockchain (beyond those privileged to see the data) advantageously increases the size of the community that is able to detect spoofing or forgery attempts. A permissioning entity limits submissions to manage blockchain growth, foreclosing problematic material that may risk long-term viability. Examples render blockchain operations resistant to advanced persistent threats (APTs), leverage digital signatures as additional trust elements for high-risk data, link records to track pedigree and enable identification of superseded (obsolete) data, and leverage out-of-band date proof to enable independent verification of integrity and no-later-than data-of-existence.
FILED Thursday, December 31, 2020
APPL NO 17/139672
ART UNIT 2431 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/64 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/50 (20220501)
H04L 9/3218 (20130101) Original (OR) Class
H04L 9/3239 (20130101)
H04L 9/3247 (20130101)
H04L 63/1483 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11863680 Wilson et al.
FUNDED BY
General Services Administration (GSA)
APPLICANT(S) Tenet 3, LLC (Dayton, Ohio)
ASSIGNEE(S) Tenet 3 LLC (Dayton, Ohio)
INVENTOR(S) Kelce S. Wilson (Murphy, Texas);  Jeff A. Hughes (Dayton, Ohio);  Tyler J. Moody (Fairborn, Ohio);  Derek E. Doran (Hilliard, Ohio);  Gary R. Tuttle (Middletown, Ohio);  Joel B. Rieman (Xenia, Ohio)
ABSTRACT A permissioned blockchain, using off-chain storage, provides advantages over blockchains that rely on consensus and/or store information within the blockchain. Advantages include enhanced viability, compactness, and the ability to register material with distribution limitations (e.g., military classified). Examples create an immutable public record of data signatures that confirm when data is intact, without distributing the data itself, so that widespread availability of the blockchain (beyond those privileged to see the data) advantageously increases the size of the community that is able to detect spoofing or forgery attempts. A permissioning entity limits submissions to manage blockchain growth, foreclosing problematic material that may risk long-term viability. Examples render blockchain operations resistant to advanced persistent threats (APTs), leverage digital signatures as additional trust elements for high-risk data, link records to track pedigree and enable identification of superseded (obsolete) data, and leverage out-of-band date proof to enable independent verification of integrity and no-later-than data-of-existence.
FILED Thursday, December 31, 2020
APPL NO 17/139694
ART UNIT 2431 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 21/64 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/50 (20220501)
H04L 9/3218 (20130101) Original (OR) Class
H04L 9/3239 (20130101)
H04L 9/3247 (20130101)
H04L 63/1483 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11856882 Das et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Kansas State University Research Foundation (Manhattan, Kansas)
ASSIGNEE(S) Kansas Stte University Research Foundation (Manhattan, Kansas)
INVENTOR(S) Sanjoy Das (Manhattan, Kansas);  Daniel Flippo (Manhattan, Kansas);  Stephen M. Welch (Manhattan, Kansas)
ABSTRACT An autonomous farming system (26) comprising one or more ground-based drones (10) and one or more unmanned aerial vehicles (12), whose routes through a field are optimized by an autonomous farming control system (30) that utilizes linearly constrained integer quadratic programming. The farming system (26) is particularly suited for farming steep terrain that is not accessible to conventional farming equipment.
FILED Friday, April 10, 2020
APPL NO 17/602014
ART UNIT 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Soil Working in Agriculture or Forestry; Parts, Details, or Accessories of Agricultural Machines or Implements, in General
A01B 69/008 (20130101) Original (OR) Class

Aeroplanes; Helicopters
B64C 39/02 (20130101)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3461 (20130101)
G01C 21/3469 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/101 (20130101)
G05D 2201/0201 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11860168 Talaat et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Adel Mohamed Talaat (Madison, Wisconsin);  Chia-wei Wu (Madison, Wisconsin)
ABSTRACT Mycobacterial-specific biomarkers and methods of using such biomarkers for diagnosis of mycobacterial infection in a mammal are disclosed.
FILED Thursday, August 29, 2019
APPL NO 16/555819
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6851 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/68 (20130101)
G01N 33/5695 (20130101)
G01N 33/6854 (20130101) Original (OR) Class
G01N 2800/26 (20130101)
G01N 2800/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11860420 Srinivasan et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Center for Nanoscale Science and Technology (CNST)
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland);  Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland);  Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland)
INVENTOR(S) Kartik Srinivasan (Rockville, Maryland);  Xiyuan Lu (Montgomery Village, Maryland)
ABSTRACT An optical cavity includes a ring defining an internal boundary and an external boundary, at least one of which is periodically modulated to define a gear-shaped configuration including a plurality of teeth, thereby enabling a plurality of slow-light modes. At least one physical defect may be defined within the periodically modulated internal boundary and/or external boundary to thereby enable at least one localized mode. At least one waveguide is coupled to the ring.
FILED Thursday, February 17, 2022
APPL NO 17/674079
ART UNIT 2874 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 20/00 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/122 (20130101)
G02B 6/12007 (20130101)
G02B 6/29338 (20130101)
G02B 6/29341 (20130101) Original (OR) Class

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 2203/15 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11861739 Meerkov et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Semyon M. Meerkov (Ann Arbor, Michigan);  Pooya Alavian (Ann Arbor, Michigan);  Liang Zhang (Ellington, Connecticut)
ABSTRACT A programmable manufacturing advisor includes an information unit that receives measurements for at least one parameter of each operation of a plurality of operations in the manufacturing process, and an analytics unit that determines a baseline performance metric for the manufacturing process based on the measurements of the at least one parameter. The programmable manufacturing advisor also includes an optimization unit that determines a recommended improvement action by determining a predicted performance metric for the manufacturing process based on an adjusted value of the at least one parameter and comparing the predicted performance metric to the baseline performance metric. The optimization unit also automatically presents the recommended improvement action to the operations manager.
FILED Thursday, October 17, 2019
APPL NO 16/656528
ART UNIT 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/4188 (20130101)
G05B 2219/32128 (20130101)
G05B 2219/33002 (20130101)
G05B 2219/40335 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/04 (20130101)
G06N 7/01 (20230101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0633 (20130101)
G06Q 10/06316 (20130101)
G06Q 10/06393 (20130101)
G06Q 50/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11858005 Nagy et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) Michael A. Nagy (Warrenton, Virginia);  Dirk H. Sattler (Gainesville, Virginia)
ABSTRACT Systems, methods, and devices for designating a location for a delivery item that is being sorted by an operator. The operator scans the delivery address of the item using a particular scanner. Using the delivery address and other information from the scanner that was used, the system determines a sort output location for the item and identifies an indicator device (e.g., an LED device) that corresponds to the sort output location. The system then commands the indicator device to present or display a designator. For example, the indicator device may be commanded to illuminate a light, such as an LED. The operator of the scanner then places the item at the location corresponding to the illuminated light designator.
FILED Friday, November 18, 2022
APPL NO 18/056950
ART UNIT 3653 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/008 (20130101)
B07C 3/14 (20130101) Original (OR) Class
B07C 3/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11858006 McGrath
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES POSTAL SERVICE (Washington, District of Columbia)
INVENTOR(S) Joseph W. McGrath (Arlington, Virginia)
ABSTRACT Systems and methods for sorting delivery items are disclosed. The system may include an intake area, a sorting area operably coupled with the intake area, and a computing system operably coupled with the intake area and the sorting area. The intake area may include a source of delivery items having a plurality of delivery items, and a scanner for scanning respective indicia of each of the plurality of delivery items. The sorting area may include a conveyor having a respective sensor disposed at opposing end portions thereof, one or more sort locations disposed about the conveyor, and one or more indicators configured to indicate a proper sort location for the delivery items. The computing system may receive data corresponding to a delivery item from the scanner, determine the proper sort location for the delivery item, and send a signal to the indicator to indicate the proper sort location.
FILED Tuesday, June 01, 2021
APPL NO 17/335783
ART UNIT 3653 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/10 (20130101)
B07C 3/18 (20130101) Original (OR) Class
B07C 2301/0008 (20130101)

Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors
B65G 1/023 (20130101)
B65G 2203/0216 (20130101)
B65G 2203/0233 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 5/38 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Treasury (TREASURY) 

US 11861966 Rich et al.
FUNDED BY
Department of the Treasury (TREASURY)
Bureau of Engraving and Printing (BEP)
APPLICANT(S) WAVEFRONT TECHNOLOGY, INC. (Paramount, California)
ASSIGNEE(S) WAVEFRONT TECHNOLOGY, INC. (Paramount, California)
INVENTOR(S) Christopher Chapman Rich (Rancho Palos Verdes, California);  Joel Mikael Petersen (Valley Village, California);  Roger Winston Phillips (Santa Rosa, California);  John Michael Tamkin (Pasadena, California)
ABSTRACT An optical device includes an array of lenses and a plurality of first and second segments disposed under the array of lenses. At a first viewing angle, the array of lenses presents a first image for viewing without presenting the second image for viewing, and at a second viewing angle different from the first viewing angle, the array of lenses presents for viewing the second image without presenting the first image for viewing. In some examples, individual ones of the first and second segments can comprise specular reflecting, transparent, diffusely reflecting, and/or diffusely transmissive features. In some examples, individual ones of the first and second segments can comprise transparent and non-transparent regions. Some examples can incorporate more than one region producing an optical effect.
FILED Thursday, September 02, 2021
APPL NO 17/446790
ART UNIT 2872 — Optics
CURRENT CPC
Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus
B42D 25/00 (20141001)
B42D 25/21 (20141001)
B42D 25/23 (20141001)
B42D 25/24 (20141001)
B42D 25/28 (20141001)
B42D 25/29 (20141001)
B42D 25/30 (20141001)
B42D 25/45 (20141001)
B42D 25/324 (20141001)
B42D 25/328 (20141001)
B42D 25/342 (20141001)
B42D 25/351 (20141001)
B42D 25/355 (20141001)
B42D 25/373 (20141001)
B42D 25/378 (20141001)
B42D 25/425 (20141001)
B42D 25/435 (20141001)
B42D 25/445 (20141001)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/55 (20130101)
G01N 21/4738 (20130101)
G01N 2201/063 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/005 (20130101)
G02B 3/0056 (20130101)
G02B 5/0278 (20130101)
G02B 5/0284 (20130101)

Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing
G07D 7/128 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Office of the Director of National Intelligence (ODNI) 

US 11861429 Strachan et al.
FUNDED BY
National Science Foundation (NSF)
Office of The Director (OD)
Office of the Director of National Intelligence (ODNI)
Intelligence Advanced Research Projects Activity (IARPA)
APPLICANT(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Spring, Texas)
INVENTOR(S) John Paul Strachan (Milpitas, California);  Dejan S. Milojicic (Milpitas, California);  Martin Foltin (Ft. Collins, Colombia);  Sai Rahul Chalamalasetti (Milpitas, California);  Amit S. Sharma (Milpitas, California)
ABSTRACT In some examples, a device includes a first processing core comprising a resistive memory array to perform an analog computation, and a digital processing core comprising a digital memory programmable with different values to perform different computations responsive to respective different conditions. The device further includes a controller to selectively apply input data to the first processing core and the digital processing core.
FILED Monday, April 30, 2018
APPL NO 17/049031
ART UNIT 2182 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 17/16 (20130101)

Hybrid Computing Arrangements
G06J 1/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11858939 Jefson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Alkermes, Inc. (Waltham, Massachusetts)
ASSIGNEE(S) Alkermes, Inc. (Waltham, Massachusetts)
INVENTOR(S) Martin R. Jefson (Stonington, Connecticut);  John A. Lowe, III (Stonington, Connecticut);  Fabian Dey (Basel, Switzerland);  Andreas Bergmann (Gauting, Germany);  Andreas Schoop (Grafrath, Germany);  Nathan Oliver Fuller (Arlington, Massachusetts)
ABSTRACT This invention provides compounds that are inhibitors of HDAC2. The compounds (e.g., compounds according to Formula I, II or any of Compounds 100-128 or any of those in Tables 2 or 3) accordingly are useful for treating, alleviating, or preventing a condition in a subject such as a neurological disorder, memory or cognitive function disorder or impairment, extinction learning disorder, fungal disease or infection, inflammatory disease, hematological disease, or neoplastic disease, or for improving memory or treating, alleviating, or preventing memory loss or impairment.
FILED Monday, December 28, 2020
APPL NO 17/134875
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/13 (20130101)
A61K 31/13 (20130101)
A61K 31/27 (20130101)
A61K 31/27 (20130101)
A61K 31/40 (20130101)
A61K 31/40 (20130101)
A61K 31/44 (20130101)
A61K 31/44 (20130101)
A61K 31/50 (20130101)
A61K 31/50 (20130101)
A61K 31/55 (20130101)
A61K 31/55 (20130101)
A61K 31/167 (20130101)
A61K 31/167 (20130101)
A61K 31/351 (20130101)
A61K 31/351 (20130101)
A61K 31/415 (20130101)
A61K 31/415 (20130101)
A61K 31/421 (20130101)
A61K 31/421 (20130101)
A61K 31/426 (20130101)
A61K 31/426 (20130101)
A61K 31/427 (20130101)
A61K 31/427 (20130101)
A61K 31/435 (20130101)
A61K 31/435 (20130101)
A61K 31/437 (20130101)
A61K 31/437 (20130101)
A61K 31/444 (20130101)
A61K 31/444 (20130101)
A61K 31/445 (20130101)
A61K 31/445 (20130101)
A61K 31/496 (20130101)
A61K 31/496 (20130101)
A61K 31/505 (20130101)
A61K 31/505 (20130101)
A61K 31/506 (20130101)
A61K 31/506 (20130101)
A61K 31/4155 (20130101)
A61K 31/4155 (20130101)
A61K 31/4192 (20130101)
A61K 31/4192 (20130101)
A61K 31/4433 (20130101)
A61K 31/4433 (20130101)
A61K 31/4439 (20130101)
A61K 31/4439 (20130101)
A61K 31/4965 (20130101)
A61K 31/4965 (20130101)
A61K 31/4985 (20130101)
A61K 31/4985 (20130101)
A61K 31/5377 (20130101)
A61K 31/5377 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 207/06 (20130101)
C07D 309/14 (20130101)
C07D 401/12 (20130101)
C07D 401/14 (20130101)
C07D 403/12 (20130101)
C07D 405/12 (20130101)
C07D 409/12 (20130101)
C07D 413/14 (20130101)
C07D 417/12 (20130101)
C07D 417/14 (20130101)
C07D 471/10 (20130101)
C07D 487/04 (20130101) Original (OR) Class
C07D 487/10 (20130101)
C07D 491/107 (20130101)
C07D 513/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11859551 O'Rorke et al.
FUNDED BY
APPLICANT(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
ASSIGNEE(S) Hamilton Sundstrand Corporation (Charlotte, North Carolina)
INVENTOR(S) Morgan O'Rorke (West Hartford, Connecticut);  Todd Haugsjaahabink (Springfield, Massachusetts);  Matej Rutar (Manchester, Connecticut);  Ryan Susca (Windsor, Connecticut)
ABSTRACT A fuel system can include a selection and shutoff valve (SSOV) configured to allow a primary flow having a primary flow pressure to pass therethrough in a first state such that the primary flow can travel to an output line. The SSOV can also be configured to shut off the primary flow in a second state to prevent the primary flow from travelling to the output line. In the second state, the SSOV can be configured to allow a secondary flow from a secondary flow source to pass therethrough such that the secondary flow can travel to the output line.
FILED Friday, January 21, 2022
APPL NO 17/581506
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/22 (20130101) Original (OR) Class
F02C 7/236 (20130101)
F02C 9/26 (20130101)
F02C 9/263 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/323 (20130101)
F05D 2240/35 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11862388 Pérez-Díaz et al.
FUNDED BY
APPLICANT(S) COUNTERFOG CORPORATION (Irving, Texas);  XTRACTION SCIENCE AND TECHNOLOGY, INC. (South Park, Pennsylvania)
ASSIGNEE(S) COUNTERFOG CORPORATION (Irving, Texas);  XTRACTION SCIENCE AND TECHNOLOGY, INC. (South Park, Pennsylvania)
INVENTOR(S) José Luis Pérez-Díaz (Valdemoro, Spain);  Steven A. Cotten (Lockport, New York)
ABSTRACT Disclosed is a design approach for intrinsically safe electromagnetic devices such as electrically actuated valves, motors, generators, or transformers intended for and capable of safe operation in explosive atmospheres or environments. The design employs a plurality of electrically insulated, intrinsically safe circuits cooperating to induce, or in the case of a generator, create a relatively large magnetic flux in the ferromagnetic core, or iron, of these devices. A method to construct such intrinsically safe devices is disclosed. These devices can be practically used in machines, mechanisms, valves, and manned or unmanned vehicles intended for safe operation in hazardous environments, for example underground coal mines or ATEX or EX classified facilities.
FILED Friday, January 14, 2022
APPL NO 17/576415
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 31/04 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 7/081 (20130101)
H01F 27/24 (20130101)
H01F 27/30 (20130101) Original (OR) Class

Dynamo-electric Machines
H02K 11/30 (20160101)
VIEW PATENT @ USPTO:  Full Text   PDF 

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Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, January 02, 2024.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

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FUNDED BY
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Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240102.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital