FedInvent™ Patents
Patent Details for Tuesday, January 09, 2024
This page was updated on Thursday, January 11, 2024 at 08:32 AM GMT
Department of Health and Human Services (HHS)
| US 11864743 | Tearney et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Guillermo J. Tearney (Cambridge, Massachusetts); Joseph Gardecki (Acton, Massachusetts); Chia-Pin Liang (Malden, Massachusetts) |
| ABSTRACT | Apparatus and method can be provided for obtaining at least one anatomical sample. For example, it is possible to provide and insert a housing into a body or provided on a hydrated anatomical structure. Further, with a source, it is possible to emit an electromagnetic radiation which causes at least the anatomical sample(s) to attach to at least one portion of the housing. A compound can be provided on a surface of the housing, and the source provides the radiation to the compound and changes properties thereof to be adhesive. The source can provide the radiation to the housing, and can change properties of a surface thereof to be adhesive. A component can be provided on a surface of the anatomical structure, and the source provides the radiation to the compound and changes properties thereof to be adhesive. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/168374 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/041 (20130101) A61B 5/0066 (20130101) A61B 5/0068 (20130101) A61B 10/04 (20130101) Original (OR) Class A61B 10/0233 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11864832 | Klin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Ami Klin (Atlanta, Georgia); Warren Jones (Decatur, Georgia) |
| ABSTRACT | Systems, devices, and methods are described for assessing the risk of developmental, cognitive, social, or mental abilities or disabilities in very young patients (e.g., in the first 2-6 months of life). Generally, the decline in visual fixation of a subject over time with respect to certain dynamic stimuli provides a marker of possible abilities or disabilities (such as ASD). The visual fixation of the subject is identified, monitored, and tracked over time through repeated eye tracking sessions, and data relating to the visual fixation is then analyzed to determine a possible increased risk certain conditions in the subject. A change in visual fixation as compared to similar visual fixation data of typically-developing subjects or to a subject's own, prior visual fixation data provides an indication of a developmental, cognitive, or mental ability or disability. |
| FILED | Tuesday, September 13, 2022 |
| APPL NO | 17/943719 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/113 (20130101) Original (OR) Class A61B 5/163 (20170801) A61B 5/167 (20130101) A61B 5/168 (20130101) A61B 2503/04 (20130101) A61B 2503/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11864865 | Culver et al. |
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| FUNDED BY |
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| APPLICANT(S) | Joseph Culver (St. Louis, Missouri); Edward Richter (St. Louis, Missouri); Adam T. Eggebrecht (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Joseph Culver (St. Louis, Missouri); Edward Richter (St. Louis, Missouri); Adam T. Eggebrecht (St. Louis, Missouri) |
| ABSTRACT | A wearable device for high-density-diffuse optical tomography includes a plurality of source modules that include source housings containing a light source. The device also includes a plurality of detector modules that include detector housings, a photodiodes, transimpedance amplifiers operatively coupled to the photodiodes, and analog to digital converters operatively coupled to the transimpedance amplifier. Each detector housing contains at least one of the photodiode, the analog to digital converter, and the transimpedance amplifier. Each source and detector housing is configurable to contact a subject's scalp and deliver or receive light from the scalp at one position. The wearable device also includes a control circuit operatively coupled to the plurality of source modules and to the plurality of detector modules to operate the source and detector modules in a coordinated manner to acquire a plurality of diffuse optical tomography measurements. |
| FILED | Tuesday, February 26, 2019 |
| APPL NO | 16/286194 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/0037 (20130101) A61B 5/0042 (20130101) A61B 5/0066 (20130101) Original (OR) Class A61B 5/684 (20130101) A61B 5/6803 (20130101) A61B 2034/2048 (20160201) A61B 2090/306 (20160201) A61B 2090/0807 (20160201) A61B 2090/3614 (20160201) A61B 2090/3937 (20160201) A61B 2562/0233 (20130101) A61B 2576/026 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02089 (20130101) G01B 9/02091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11864964 | Esquivel-Upshaw et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Josephine F. Esquivel-Upshaw (Gainesville, Florida); Fan Ren (Gainesville, Florida); Patrick Carey (Malden, Massachusetts); Arthur E. Clark, Jr. (Newberry, Florida); Christopher D. Batich (Gainesville, Florida) |
| ABSTRACT | Disclosed herein is a method for forming an anti-microbial layer on an apparatus. Also disclosed is a method for improving the anti-bacterial properties of a titanium device coated with titanium-nitride (TiN). Also disclosed is a medical apparatus comprising an anti-microbial layer prepared by the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Wednesday, July 31, 2019 |
| APPL NO | 17/258022 |
| ART UNIT | 3772 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 8/0013 (20130101) A61C 13/0835 (20130101) Original (OR) Class A61C 2201/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865033 | Maier et al. |
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| FUNDED BY |
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| APPLICANT(S) | Reia, LLC (Lyme, New Hampshire) |
| ASSIGNEE(S) | Reia, LLC (Lyme, New Hampshire) |
| INVENTOR(S) | Kaitlin E. Maier (Darien, Connecticut); Meegan P. Daigler (Portland, Maine); Ariana M. Sopher (Somerville, Massachusetts) |
| ABSTRACT | A pessary providing various structures, parts, and components to enable the pessary to remain deployed in a supportive position so that it may reliably provide the desired supportive capabilities. A ridge structure prevents over-rotation of the supportive members. The pessary can be formed preferably by injection molding where the mold has at least one insert. The geometry of the pessary can enable the pessary to have the required stiffness, flexibility, hinged capability, and softness where needed to achieve a pessary that is superior to prior art pessaries. |
| FILED | Wednesday, May 26, 2021 |
| APPL NO | 17/331312 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 6/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865086 | Harrelson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Pacific University (Forest Grove, Oregon) |
| ASSIGNEE(S) | PACIFIC UNIVERSITY (Forest Grove, Oregon) |
| INVENTOR(S) | John P. Harrelson (Forest Grove, Oregon); Deepa A. Rao (Beaverton, Oregon) |
| ABSTRACT | Compounds, compositions, and methods of use of such compounds and compositions are provided for reducing human dependency to nicotine. In one example, a method of treating an individual with an addiction to nicotine comprises administering to the individual a compound that is a structural analog of trans-cinnamaldehyde. Based on the administration, a rate at which nicotine is metabolized may be reduced, which in turn may reduce a desire for the individual to consume nicotine-containing products. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/649328 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/11 (20130101) Original (OR) Class A61K 31/465 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/34 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865093 | Mrsny et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts); UNIVERSITY OF BATH (Bath, United Kingdom) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts); University of Bath (Bath, United Kingdom) |
| INVENTOR(S) | Randall Mrsny (Los Altos Hills, California); Beth McCormick (Haverhill, Massachusetts); Roland Ellwood Dolle (Ashland, Massachusetts) |
| ABSTRACT | Disclosed herein are methods and compositions for treating neutrophil-mediated inflammation by targeting, in any combination, the pro-inflammatory MRP2/HXA3 pathway and/or the anti-inflammatory P-gp/endocannabinoid pathway and/or the anti-inflammatory MRP 1/L-AMEND pathway, comprising administering to the subject a therapeutically effective amount of (a) one or more first compound that inhibits the activity and/or level of one or more of multidrug resistance protein 2 (MRP2) and hepoxilin A3 (HXA3) synthase, and/or (b) one or more second compound that increases the level and/or activity of one or more N-acylethanolamines (NAEs), and/or (c) one or more third compound that increases the level and/or activity of multidrug resistance protein 1 (MRP1), wherein the therapeutic amount of the first, second, and third compounds reduces migration of neutrophils into the target tissue. |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/631023 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) Original (OR) Class A61K 47/60 (20170801) A61K 47/61 (20170801) A61K 47/593 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865101 | Lopez-Mejias et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vilmali Lopez-Mejias (San Juan, Puerto Rico); Jeaninna P. Flores Bello (San Juan, Puerto Rico); Israel Rodriguez Rodriguez (San Juan, Puerto Rico); Joyce Marie Serrano Valcarcel (San Juan, Puerto Rico) |
| ASSIGNEE(S) | University of Puerto Rico (San Juan, Puerto Rico) |
| INVENTOR(S) | Vilmali Lopez-Mejias (San Juan, Puerto Rico); Jeaninna P. Flores Bello (San Juan, Puerto Rico); Israel Rodriguez Rodriguez (San Juan, Puerto Rico); Joyce Marie Serrano Valcarcel (San Juan, Puerto Rico) |
| ABSTRACT | A series of pharmaceutical metal complexes (pMCs) were produced and characterized using the mast cell stabilizer, cromolyn, and bioactive metal ions (Zn+2, Mg+2, and Ca+2). Three novel pMCs, Cromolyn-Zn, Cromolyn-Mg, and Cromolyn-Ca were formed through reactions under controlled temperature and pH conditions. TGA demonstrated that these metal complexes showed an enhanced thermal stability due to the strong coordination with the ligand, cromolyn. PXRD data indicates a high degree of crystallinity as well as a unique packing arrangement for each pMCs. SEM analysis showed materials with well-defined morphologies while EDS presented elemental evidence for the unique composition of each pMCs. The crystal structure for these materials was elucidated through SCXRD, and a variety of binding modes and packing motifs were found within each respective metal complex. Only 2D structures were achieved under the conditions studied. Dissolution studies show high stability and slow degradation for the metal complexes, while a higher dissolution was observed for the drug compound in PBS. Neither CS nor the pMCs dissolved significantly in FaSSGF at 37° C. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/307208 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865103 | Kumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Alagramam N. Kumar (Cleveland, Ohio); Suhasini Gopal Ramanujam (Cleveland, Ohio) |
| ABSTRACT | A method of treating a glycosylation-defective protein associated disease or disorder in a subject, the method includes administering to the subject a therapeutically effective amount of a Sarco/ER ATPase (SERCA) inhibitor. |
| FILED | Tuesday, September 07, 2021 |
| APPL NO | 17/468274 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/343 (20130101) A61K 31/357 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865125 | Farese et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); UNITED STATES DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Robert Vito Farese (St. Petersburg, Florida); Mini Paliyath Sajan (Wesley Chapel, Florida); Margaret Genevieve Higgs (St. Petersburg, Florida) |
| ABSTRACT | Provided herein are formulations effective for and methods of treating or preventing a neurodegenerative disorder in a subject in need thereof that can include administering an amount of an aPKC inhibitor to a subject in need thereof. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 17/554924 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/675 (20130101) Original (OR) Class A61K 33/242 (20190101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Enzymes C12Y 304/23046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865128 | Baasov et al. |
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| FUNDED BY |
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| APPLICANT(S) | Technion Research and Development Foundation Limited (Haifa, Israel) |
| ASSIGNEE(S) | Technion Research and Development Foundation Limited (Haifa, Israel) |
| INVENTOR(S) | Timor Baasov (Haifa, Israel); Dana Atia-Glikin (Schania, Israel); Jeyakumar Kandasamy (Trichy, India); Valery Belakhov (Haifa, Israel) |
| ABSTRACT | A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5″ position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification. |
| FILED | Thursday, April 08, 2021 |
| APPL NO | 17/226050 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7036 (20130101) Original (OR) Class A61K 45/06 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 79/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 5/06 (20130101) C07H 13/04 (20130101) C07H 15/23 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865136 | Machielse et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mandos LLC (West Hollywood, California) |
| ASSIGNEE(S) | Mandos LLC (West Hollywood, California) |
| INVENTOR(S) | Bernardus Nicolaas Machielse (North Potomac, Maryland); Allan Darling (North Potomac, Maryland) |
| ABSTRACT | This disclosure provides mixtures of beta-cyclodextrin molecules substituted at one or more hydroxyl positions by hydroxypropyl groups, the mixture optionally including unsubstituted beta-cyclodextrin molecules, for use as a pharmaceutically active ingredient; methods of making such mixtures; methods of qualifying such mixtures for use in a pharmaceutical composition suitable for intrathecal or intracerebroventricular administration; pharmaceutical compositions suitable for intrathecal or intracerebroventricular administration comprising such mixtures; and methods of using the pharmaceutical compositions for treatment of Niemann-Pick disease Type C. |
| FILED | Wednesday, March 01, 2023 |
| APPL NO | 18/115898 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/724 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865144 | Anker et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan F. Anker (Chicago, Illinois); Praveen Thumbikat (Chicago, Illinois); Sarki A. Abdulkadir (Lombard, Illinois); Anthony J. Schaeffer (Hinsdale, Illinois) |
| ABSTRACT | Provided herein are composition and methods for the treatment of cancer by the administration of uropathogenic bacteria. In particular, CP1 E. coli is administered for the treatment of prostate cancer. |
| FILED | Wednesday, August 01, 2018 |
| APPL NO | 16/052285 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 39/0258 (20130101) A61K 39/0258 (20130101) A61K 39/001193 (20180801) A61K 39/001194 (20180801) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/523 (20130101) A61K 2039/585 (20130101) A61K 2039/884 (20180801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865150 | Galanis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Evanthia Galanis (Rochester, Minnesota); S. Keith Anderson (Rochester, Minnesota); Cheyne B. Kurokawa (Rochester, Minnesota); Ianko D. Iankov (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials involved in treating cancer. For example, methods and materials for using an inhibitor of UFM1 activity or expression and/or an inhibitor of UFL1 activity or expression to reduce a cancer cell's ability to carry out a DDR, thereby increasing the sensitivity of cancer cells to treatment with a DNA damaging therapy such as radiation or chemotherapy, are provided. |
| FILED | Thursday, January 11, 2018 |
| APPL NO | 16/477830 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 35/768 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2760/18432 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865157 | Udugamasooriya et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas); The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas); The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Damith Gomika Udugamasooriya (Katy, Texas); Aaron Raymond (Houston, Texas); John Minna (Dallas, Texas) |
| ABSTRACT | Described herein are pharmaceutical compositions containing peptoids of general formula (I), (II), or (III) capable of reducing proliferation of cancer stem cells in a subject and methods of treatment or prophylactic administration of these pharmaceutical compositions to treat cancer. Also provided herein are method of detecting and treating cancerous cell masses by use of peptoids of general formula (I), (II), or (III). |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/157648 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) Original (OR) Class A61K 47/64 (20170801) A61K 47/65 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865158 | Yeo et al. |
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| FUNDED BY |
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| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Yoon Yeo (West Lafayette, Indiana); Simseok Yuk (Lafayette, Indiana) |
| ABSTRACT | The present invention generally relates to a process of nanoparticle formulations and its composition matter for systemic treatment of sepsis. In particular, this invention discloses a method for preparing tannic acid-ferric nanoparticles, optionally incorporating a component of vitamin D3, coated with zwitterionic chitosan (ZWC) and polymyxin B (PMB). The invention described herein also pertains to pharmaceutical compositions and methods for the treatment of sepsis. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 17/636453 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) A61K 31/7032 (20130101) A61K 33/26 (20130101) A61K 38/12 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/36 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865162 | Xie et al. |
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| FUNDED BY |
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| APPLICANT(S) | MARSHALL UNIVERSITY RESEARCH CORPORATION (Huntington, West Virginia) |
| ASSIGNEE(S) | MARSHALL UNIVERSITY RESEARCH CORPORATION (Huntington, West Virginia) |
| INVENTOR(S) | Zijian Xie (Huntington, West Virginia); Joseph I. Shapiro (Huntington, West Virginia); Jiang Liu (Huntington, West Virginia) |
| ABSTRACT | Methods for treating uremic cardiomyopathy are provided and include the step of administering a polypeptide antagonist of a Na/K ATPase/Src receptor complex to a subject in need thereof. The polypeptide anatagonist can further include a cell penetrating polypeptide. Methods of treating anemia, including anemia-associated with chronic kidney disease, are also provided. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 16/313741 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/005 (20130101) A61K 38/46 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865167 | Brogdon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Novartis AG (Basel, Switzerland); The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania); UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Novartis AG (Basel, Switzerland); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jennifer Brogdon (Sudbury, Massachusetts); Laura Alexandra Johnson (Media, Pennsylvania); Carl H. June (Merion Station, Pennsylvania); Andreas Loew (Boston, Massachusetts); Marcela Maus (Lexington, Massachusetts); John Scholler (Narberth, Pennsylvania); Hideho Okada (Pittsburgh, Pennsylvania) |
| ABSTRACT | The invention provides compositions and methods for treating diseases associated with expression of EGFRvIII. The invention also relates to chimeric antigen receptor (CAR) specific to EGFRvIII, vectors encoding the same, and recombinant T cells comprising the anti-EGFRvIII CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises an anti-EGFRvIII binding domain. |
| FILED | Friday, April 12, 2019 |
| APPL NO | 16/382402 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 39/001102 (20180801) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 16/2863 (20130101) C07K 16/3053 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865168 | Shalek et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America, as represented by The Secretary, Department of Health and Human Services (Bethesda, Maryland); University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The United States of America, as represented by The Secretary, Department of Health and Human Services (Bethesda, Maryland); University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Alexander K. Shalek (Cambridge, Massachusetts); Travis Hughes (Cambridge, Massachusetts); Marc H. Wadsworth (Cambridge, Massachusetts); Robert Seder (Bethesda, Maryland); Mario Roederer (Bethesda, Maryland); Joanne L. Flynn (Pittsburgh, Pennsylvania); Patricia Darrah (Bethesda, Maryland) |
| ABSTRACT | Provided herein are compositions and methods for therapeutic and/or prophylactic treatment of an intracellular bacterial infection in a subject in need thereof, comprising one or more modulating agents, wherein the one or more modulating agents increase expression of IFNγ, IL-2, TNF, and/or IL-17 in systemic and/or lung T cells. In some embodiments, the increase of expression of IFNγ, IL-2, TNF, and/or IL-17 occurs in lung T cells. The lung T cells can be lung resident T cells or systemic T cells that are recruited to the lung. In some embodiments, the T cells are CD4+ and/or CD8+ T cells. In some embodiments, the intracellular bacterial infection is a Mycobacterium tuberculosis (MTB) infection. |
| FILED | Wednesday, December 30, 2020 |
| APPL NO | 17/137481 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) Original (OR) Class A61K 2039/54 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865172 | Crawford et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida); CORNELL RESEARCH FOUNDATION, INC. (Ithaca, New York); The Government of The United States of America as represented by The Secretary of the Department of (Atlanta, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida); CORNELL RESEARCH FOUNDATION, INC. (Ithaca, New York); THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION (Atlanta, Georgia) |
| INVENTOR(S) | Patti Cynthia Crawford (Gainesville, Florida); Paul J. Gibbs (Gainesville, Florida); Edward J. Dubovi (Ithaca, New York); Ruben Omar Donis (Atlanta, Georgia); Jacqueline Katz (Atlanta, Georgia); Alexander I. Klimov (Atlanta, Georgia); Nallakannu P. Lakshmanan (Millsboro, Delaware); Melissa Anne Lum (Millsboro, Delaware); Daniel Ghislena Emiel Goovaerts (Boxmeer, Netherlands); Mark William Mellencamp (Desoto, Kansas); Nancy J. Cox (Atlanta, Georgia); William L. Castleman (Gainesville, Florida) |
| ABSTRACT | The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/471370 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/552 (20130101) A61K 2039/5252 (20130101) A61K 2039/55555 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/005 (20130101) C07K 16/1018 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/24043 (20130101) C12N 2760/16121 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) C12N 2760/16151 (20130101) C12N 2760/16171 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865173 | Palese et al. |
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| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | Peter Palese (New York, New York); Adolfo Garcia-Sastre (New York, New York); Megan Ermler (New York, New York); Florian Krammer (New York, New York) |
| ABSTRACT | Provided herein are chimeric hemagglutinin (HA) polypeptides and uses thereof for inducing an immune response (e.g., an antibody response) against influenza virus. Also provided herein are methods of generating antibodies to the chimeric HA polypeptides in a subject. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/583088 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/525 (20130101) A61K 2039/545 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) C12N 2760/16171 (20130101) C12N 2760/16222 (20130101) C12N 2760/16234 (20130101) C12N 2760/16271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865174 | Mason et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hugh Mason (Phoenix, Arizona); Andrew Diamos (Tempe, Arizona); Mary Pardhe (Phoenix, Arizona); Brandon Favre (Los Gatos, California) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Hugh Mason (Phoenix, Arizona); Andrew Diamos (Tempe, Arizona); Mary Pardhe (Phoenix, Arizona); Brandon Favre (Los Gatos, California) |
| ABSTRACT | The disclosure relates to vaccination compositions, for example, against human papillomavirus, Zika virus, and flu virus. The disclosure also relates to vectors for producing the virus-like particles and immune complex platforms of the vaccination compositions. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/367296 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 39/292 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/505 (20130101) A61K 2039/575 (20130101) A61K 2039/5258 (20130101) A61K 2039/6056 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/20023 (20130101) C12N 2710/20034 (20130101) C12N 2710/20071 (20130101) C12N 2730/10123 (20130101) C12N 2730/10134 (20130101) C12N 2730/10171 (20130101) C12N 2760/16123 (20130101) C12N 2760/16134 (20130101) C12N 2760/16171 (20130101) C12N 2770/24134 (20130101) C12N 2770/24171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865181 | Shrader et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (, None) |
| INVENTOR(S) | Alanna Schepartz Shrader (New Haven, Connecticut); Kim Quach (New Haven, Connecticut) |
| ABSTRACT | This invention is generally related to modified peptidic oligomers that have an increased ability to reach the cytosol or nucleus. In some embodiments, the modified peptidic oligomer molecules deliver an associated cargo molecule to the cytosol or nucleus. Other embodiments of the invention relate to modified peptidic oligomer fusion molecules that reach the cytosol or nucleus. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/761364 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6455 (20170801) Original (OR) Class A61K 49/0041 (20130101) Peptides C07K 7/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865286 | Aran et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kiana Aran (Berkeley, California); Jacobo Paredes (Berkeley, California); Niren Murthy (Berkeley, California); Dorian Liepmann (Lafayette, California); Kunwoo Lee (Albany, California) |
| ABSTRACT | Provided are active agent delivery devices configured to deliver an active agent formulation into or through a mucosal layer in a subject. The active agent delivery devices include a power reservoir configured to eject the active agent formulation at a pressure sufficient to deliver the active agent formulation into or through a mucosal layer in a subject. Methods of using the subject active agent delivery devices are also provided. |
| FILED | Tuesday, June 23, 2020 |
| APPL NO | 16/909695 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 39/0005 (20130101) A61K 2039/542 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 31/00 (20130101) A61M 31/002 (20130101) Original (OR) Class A61M 2202/064 (20130101) A61M 2205/36 (20130101) A61M 2205/3324 (20130101) A61M 2205/3334 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865302 | Epshteyn et al. |
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| FUNDED BY |
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| APPLICANT(S) | Nuwellis, Inc. (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | NUWELLIS, INC. (Eden Prairie, Minnesota) |
| INVENTOR(S) | Vitaliy Gennad'yevich Epshteyn (Maple Grove, Minnesota); Steven Daniel Sandoval (Eden Prairie, Minnesota); Kalley Francis Berg (Lino Lakes, Minnesota); Franz Willems Ulrich (Minneapolis, Minnesota); Travis Ernest Yoch (Woodbury, Minnesota); Robert Russell Roberts, III (St. Paul, Minnesota) |
| ABSTRACT | An extracorporeal blood filtering machine can include a blood circuit, an effluent circuit, and a source fluid circuit and can be controlled by a controller. The extracorporeal blood filtering machine can also include access ports for connecting the source fluid circuit to the blood circuit, as well as blood sensors to detect possible issues with the extracorporeal blood filtering machine. The extracorporeal blood filtering machine can include density sensors and flow sensors that enable it to be more accurate and to operate while being transported. The extracorporeal blood filtering machine can further include a user interface and can display fluid inflow/outflow information. A medical fluid container can automatically empty after being filled. An apparatus for supporting a medical fluid container can include a hanger and an attachment member with the apparatus able to adjust to ensure the medical fluid container remains properly oriented directly under a medical fluid container scale. |
| FILED | Monday, February 20, 2023 |
| APPL NO | 18/171612 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/165 (20130101) A61M 5/172 (20130101) Original (OR) Class A61M 5/1415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865326 | Herbst et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ewa Herbst (Edgewater, New Jersey); Lisa A. Schmidt (Sparta, New Jersey) |
| ASSIGNEE(S) | Innovations Holdings, L.L.C. (Edgwater, New Jersey) |
| INVENTOR(S) | Ewa Herbst (Edgewater, New Jersey); Lisa A. Schmidt (Sparta, New Jersey) |
| ABSTRACT | A multi-functional electrical stimulation (ES) system adapted to yield output signals for effecting faradic, electromagnetic, or other forms of electrical stimulation for a broad spectrum of different biological and bio-medical applications. The system includes and ES signal stage having a selector coupled to a plurality of different signal generators, each generator producing a signal having a distinct shape such as a sine, a square or sawtooth wave or a simple or complex pulse form, the parameters of which are adjustable in regard to amplitude, duration, repetition rate and other variables. The signal from the selected generator in the ES stage is fed to at least one output stage where it is processed to produce a high or low voltage or current output of a desired polarity whereby the output stage is capable of yielding an electrical stimulation signal appropriate for its intended application. Also included in the system is a measuring stage which measures and displays the electrical stimulation signal operating on the substance being treated as well as the outputs of various sensors which sense conditions prevailing in this substance whereby the user of the system can adjust it to yield an electrical stimulation signal of whatever type he wishes and can then observe the effects of this signal on a substance being treated. |
| FILED | Tuesday, February 22, 2005 |
| APPL NO | 11/063195 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3603 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865346 | Tai |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Changfeng Tai (Wexford, Pennsylvania) |
| ABSTRACT | Provided herein is a method of blocking a nerve or neuron by applying an electrical stimulation to the nerve or neuron, wherein the electrical stimulation is of an intensity below the excitation threshold of the nerve or neuron for a length of time sufficient to produce a block of nerve conduction or neuron excitation. |
| FILED | Monday, April 15, 2019 |
| APPL NO | 17/047754 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/36062 (20170801) A61N 1/36071 (20130101) A61N 1/36153 (20130101) A61N 1/36157 (20130101) A61N 1/36164 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865534 | Walsh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bruce Walsh (Londonderry, New Hampshire); Boris Blanter (Lexington, Massachusetts); Matthew Barra (Hingham, Massachusetts); Brian Connolly (Winthrop, Massachusetts); Greg Yantz (Somerville, Massachusetts); Paul Gervasio (North Billerica, Massachusetts); Don Straus (Charlestown, Massachusetts) |
| ASSIGNEE(S) | FIRST LIGHT DIAGNOSTICS, INC. (Chelmsford, Massachusetts) |
| INVENTOR(S) | Bruce Walsh (Londonderry, New Hampshire); Boris Blanter (Lexington, Massachusetts); Matthew Barra (Hingham, Massachusetts); Brian Connolly (Winthrop, Massachusetts); Greg Yantz (Somerville, Massachusetts); Paul Gervasio (North Billerica, Massachusetts); Don Straus (Charlestown, Massachusetts) |
| ABSTRACT | The invention provides analyzers that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient and specific selection and sensitive imaging detection of individual microscopic targets at low magnification. Automated embodiments allow efficient walk-away, on-demand, random-access high-throughput testing. The analyzers perform tests without requiring wash steps thus streamlining engineering and lowering costs. Thus, the invention provides analyzers that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests for analytes. |
| FILED | Thursday, September 24, 2009 |
| APPL NO | 13/120533 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/117 (20130101) A61B 5/151 (20130101) A61B 5/157 (20130101) A61B 5/15113 (20130101) A61B 5/15186 (20130101) A61B 5/150022 (20130101) A61B 5/150213 (20130101) A61B 5/150221 (20130101) A61B 5/150274 (20130101) A61B 5/150305 (20130101) A61B 5/150343 (20130101) A61B 5/150351 (20130101) A61B 5/150412 (20130101) A61B 5/150503 (20130101) A61B 5/150786 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/5029 (20130101) B01L 3/5082 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 7/00 (20130101) B01L 9/52 (20130101) B01L 2200/10 (20130101) B01L 2200/025 (20130101) B01L 2200/026 (20130101) B01L 2200/027 (20130101) B01L 2200/0605 (20130101) B01L 2300/022 (20130101) B01L 2300/042 (20130101) B01L 2300/043 (20130101) B01L 2300/046 (20130101) B01L 2300/048 (20130101) B01L 2300/0654 (20130101) B01L 2300/0681 (20130101) B01L 2300/0864 (20130101) B01L 2400/043 (20130101) B01L 2400/0406 (20130101) B01L 2400/0409 (20130101) B01L 2400/0415 (20130101) B01L 2400/0457 (20130101) B01L 2400/0472 (20130101) B01L 2400/0481 (20130101) B01L 2400/0677 (20130101) B01L 2400/0683 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/03 (20130101) G01N 21/253 (20130101) G01N 21/6428 (20130101) G01N 21/6452 (20130101) G01N 21/6458 (20130101) G01N 33/54373 (20130101) G01N 35/02 (20130101) G01N 35/025 (20130101) G01N 35/0098 (20130101) G01N 2021/0325 (20130101) G01N 2021/0346 (20130101) G01N 2035/0401 (20130101) G01N 2035/0429 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865785 | Dean et al. |
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| FUNDED BY |
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| APPLICANT(S) | H. David Dean (Shaker Heights, Ohio); Al Siblani (Dearborn Heights, Michigan); Eric J. Mott (Plainwell, Michigan); John P. Fisher (Kensington, Maryland); Martha O. Wang (Columbia, Missouri); Antonios G. Mikos (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | H. David Dean (Shaker Heights, Ohio); Al Siblani (Dearborn Heights, Michigan); Eric J. Mott (Plainwell, Michigan); John P. Fisher (Kensington, Maryland); Martha O. Wang (Columbia, Missouri); Antonios G. Mikos (Houston, Texas) |
| ABSTRACT | A process for additive manufacturing of a resorbable implant to be implanted into a patient includes providing a biocompatible resin including a liquid light-polymerizable material that is resorbable after polymerization and an initiator. The process further includes actuating an additive manufacturing apparatus to expose an amount of the biocompatible resin to light to at least partially cure the exposed amount of biocompatible resin to form a layer of the resorbable implant and actuating the additive manufacturing apparatus to expose at least some additional amount of biocompatible resin to light to at least partially cure the exposed additional amount of biocompatible resin to form an additional layer of the resorbable implant and to at least partially overcure previously cured layers to cause at least some interlayer binding between the previously cured layers and the additional layer. |
| FILED | Tuesday, June 27, 2017 |
| APPL NO | 15/634792 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/50 (20130101) A61L 27/56 (20130101) A61L 27/60 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/135 (20170801) B29C 64/386 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Optical Elements, Systems, or Apparatus G02B 26/0833 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/029 (20130101) G03F 7/0047 (20130101) G03F 7/105 (20130101) G03F 7/2008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866394 | Slusher et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Institute of Organic Chemistry and Biochemistry AS CR v.v.i. (Prague, Czech Republic) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSTY (Baltimore, Maryland); INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR V.V.I. (Prague, Czech Republic) |
| INVENTOR(S) | Barbara Slusher (Kingsville, Maryland); Rana Rais (West Friendship, Maryland); Jan Vavra (Prague, Czech Republic); Tomas Tichy (Prague, Czech Republic); Pavel Majer (Sykesville, Maryland); Andrej Jancarik (Koprivnice, Czech Republic); Lukas Tenora (Kretin, Czech Republic) |
| ABSTRACT | Prodrugs of hydroxamate-based GCPII inhibitors and methods of their use for treating a disease or condition are disclosed. |
| FILED | Monday, July 12, 2021 |
| APPL NO | 17/372899 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/02 (20180101) Acyclic or Carbocyclic Compounds C07C 259/06 (20130101) Original (OR) Class C07C 259/08 (20130101) Heterocyclic Compounds C07D 317/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866398 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Jiaming Li (Pasadena, California); Xu Chen (Pasadena, California); Tonia S. Ahmed (Pasadena, California); Brian M. Stoltz (Pasadena, California); Robert H. Grubbs (Pasadena, California) |
| ABSTRACT | This invention relates generally to the synthesis of Δ12-Prostaglandin J product using stereoretentive ruthenium olefin metathesis catalysts supported by dithiolate ligands. Δ12-Prostaglandin J products were generated with excellent selectivity (>99% Z) and in moderate to high/good yields (47% to 80% yield; 58% to 80% yield). |
| FILED | Tuesday, May 14, 2019 |
| APPL NO | 17/055970 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/462 (20130101) Acyclic or Carbocyclic Compounds C07C 405/0016 (20130101) Original (OR) Class C07C 2601/10 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866407 | Wang |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Jun Wang (Tucson, Arizona) |
| ABSTRACT | This invention is in the field of medicinal chemistry and relates to a new class of small-molecules having a pyrrolidinone-acetamide (or similar) structure (e.g., Formula I) which function as inhibitors of the SARS-CoV-2 papain-like protease (PLpro), which function as inhibitors of the SARS-CoV-2 related viral 3CL protease (MPpro), which function as therapeutics for the treatment of viral infection characterized with PLPpro and/or Mpro protease activity and/or expression (e.g., COVID-19), and which function as therapeutics for the treatment of other conditions characterized with PLPpro and/or Mpro protease activity and/or expression. |
| FILED | Tuesday, April 19, 2022 |
| APPL NO | 17/724125 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/16 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 31/14 (20180101) Heterocyclic Compounds C07D 207/46 (20130101) C07D 207/273 (20130101) Original (OR) Class C07D 209/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866415 | Yu et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Jin-quan Yu (San Diego, California); Zhe Zhuang (San Diego, California) |
| ABSTRACT | Provided herein is a method of forming a beta-lactone from a carboxylic acid having a beta-carbon with a hydrogen atom disposed thereon. The method comprises contacting a carboxylic acid of formula (1) as described herein with an effective amount of a palladium(II) catalyst, an effective amount of an N-protected aminoacid ligand, and t-butylhydroperoxide in a solvent comprising hexafluoroisopropanol (HFIP), at about 60° C. to provide a beta-lactone of formula (2) as described herein. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 17/615509 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 305/12 (20130101) Original (OR) Class C07D 405/06 (20130101) C07D 407/04 (20130101) C07D 407/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6551 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866416 | Velu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Sadanandan E. Velu (Birmingham, Alabama); Hui Wu (Hoover, Alabama); Qiong Zhang (Sichuan, China PRC); Bhavitavya Nijampatnam (Birmingham, Alabama) |
| ABSTRACT | The present invention is related to the inhibition of the formation of Streptococci biofilms through the inhibition of glucosyl transferase (Gtf). Compounds, compositions and methods for inhibiting Streptococcus biofilm formation, as well as for preventing, inhibiting and/or treating the formation of dental caries, and methods of identifying compounds that prevent, inhibit and/or treat the formation of dental caries are provided. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 17/044483 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Heterocyclic Compounds C07D 333/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866421 | Beaton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Epigen Biosciences, Inc. (San Diego, California) |
| ASSIGNEE(S) | Epigen Biosciences, INC. (San Diego, California) |
| INVENTOR(S) | Graham Beaton (Vista, California); Fabio Tucci (San Diego, California); Satheesh Ravula (San Diego, California); Suk Joong Lee (San Diego, California); Chandravadan Shah (San Diego, California) |
| ABSTRACT | Pyrimidine and Pyridine containing compounds are described herein that are enzyme p70S6K inhibitors useful in the treatment of S6K-dependent or S6K-mediated diseases and conditions, including but not limited to cancer, fibrotic metabolic and certain neurological disorders. |
| FILED | Monday, May 31, 2021 |
| APPL NO | 17/334921 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) C07D 403/04 (20130101) Original (OR) Class C07D 405/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866427 | Kumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Icahn School of Medicine at Mount Sinai (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | Kunal Kumar (New York, New York); Peng Wang (New York, New York); Roberto Sanchez (New York, New York); Adolfo Garcia Ocaña (New York, New York); Andrew Stewart (New York, New York); Robert Devita (New York, New York) |
| ABSTRACT | Described herein are compounds having the following structure: formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof. Also disclosed are compositions containing the compounds, methods of inhibiting activity of DYRK1 A in a cell, methods of increasing cell proliferation in a population of pancreatic beta cells, methods of treating a subject for a condition associated with insufficient insulin secretion, and methods of treating a subject for a neurological disorder. |
| FILED | Wednesday, March 20, 2019 |
| APPL NO | 16/981742 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866440 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NOVITA PHARMACEUTICALS, INC. (New York, New York); CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York); NOVITA PHARMACEUTICALS, INC. (New York, New York) |
| INVENTOR(S) | Xin-Yun Huang (New York, New York); Christy Young Shue (Irvine, California) |
| ABSTRACT | Provided are compositions and methods for treating a condition or disorder mediated by fascin activity in a subject in need thereof which method comprises administering to the subject a therapeutically effective amount of at least one compound of any one of Formula I-a to I-n, II, II-a, II-b or III or a pharmaceutically acceptable salt thereof. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/160948 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) A61K 31/433 (20130101) A61K 31/522 (20130101) Heterocyclic Compounds C07D 249/12 (20130101) C07D 277/82 (20130101) C07D 285/08 (20130101) C07D 405/12 (20130101) C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866462 | Nakai et al. |
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| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Hiroyuki Nakai (Portland, Oregon); Kei Adachi (Portland, Oregon) |
| ABSTRACT | Disclosed are adeno-associated viral vectors and plasmids encoding the same. Also disclosed are methods of using adeno-associated viral vectors to deliver a protein of interest to the subject. The disclosed vectors have phenotypes including but not limited to increased retention in the blood of a subject, avoidance of the liver, and transduction of the brain and other tissues. |
| FILED | Wednesday, May 03, 2017 |
| APPL NO | 16/098814 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2830/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866468 | Chugh |
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| FUNDED BY |
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| APPLICANT(S) | Sumant S Chugh (Oak Park, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sumant S Chugh (Oak Park, Illinois) |
| ABSTRACT | The present disclosure provides a polypeptide and method for treating and/or preventing nephrotic syndrome, such as but not limited to those associated with minimal change disease and membranous nephropathy, and conditions related to nephrotic syndrome, such as but not limited to, proteinuria and edema, as well as diabetic nephropathy, diabetes mellitus, lupus nephritis or primary glomerular disease. The present disclosure further provides methods for reducing proteinuria and other disease states as discussed herein. Such methods comprise the therapeutic delivery of an Angptl4 polypeptide or Angptl4 polypeptide derivative to a subject. |
| FILED | Monday, July 16, 2018 |
| APPL NO | 16/036643 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1275 (20130101) A61K 35/16 (20130101) A61K 38/00 (20130101) A61K 38/04 (20130101) A61K 38/12 (20130101) A61K 38/16 (20130101) A61K 38/38 (20130101) A61K 38/42 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 14/76 (20130101) C07K 14/515 (20130101) C07K 14/765 (20130101) C07K 14/775 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866469 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Klogenix LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Klogenix LLC (Boston, Massachusetts) |
| INVENTOR(S) | Ci-Di Chen (Boston, Massachusetts) |
| ABSTRACT | The present disclosure relates to compositions and methods for modulating gene expression and in particular to DNA binding proteins and their use for increasing expression of Klotho. In some examples, the present disclosure provides an isolated or recombinant DNA binding protein comprising or attached to a transcriptional activation domain wherein the DNA binding protein binds to a target sequence within or near a Klotho gene. |
| FILED | Monday, December 16, 2019 |
| APPL NO | 17/287218 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/005 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 2319/81 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866474 | Cai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Jianfeng Cai (Tampa, Florida); Sami Abdulkadir (Tampa, Florida) |
| ABSTRACT | Provided herein are novel VEGF mimics, pharmaceutical compositions thereof, and methods of their use in increasing or reducing angiogenesis. |
| FILED | Wednesday, December 21, 2022 |
| APPL NO | 18/069797 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Peptides C07K 14/475 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866480 | Hirsch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Matthew Louis Hirsch (Chapel Hill, North Carolina); Brian Christopher Gilger (Raleigh, North Carolina) |
| ABSTRACT | This invention relates to vectors for delivery of human leukocyte antigen G to the eye and/or to cornea explants and methods of using the same for treatment and/or prevention of corneal transplant rejection and other disorders associated with an immune response and/or vascularization. |
| FILED | Wednesday, July 26, 2017 |
| APPL NO | 16/318070 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) A61P 37/06 (20180101) Peptides C07K 14/70539 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14142 (20130101) C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) C12N 2830/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866685 | Jabbarzadeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| INVENTOR(S) | Ehsan Jabbarzadeh (Columbia, South Carolina); Christopher Wu (Matthews, North Carolina) |
| ABSTRACT | Biocompatible, mechanically-dynamic thermoresponsive devices, methods for forming the devices, and exemplary applications for the devices are described. The devices include a series of wells therein and provide for temperature-controlled mechanostimulation of single cells or groups of cells that can be retained in the wells of a device. Mechanostimulation can be single instance of any duration, continuous, or regular or irregular cyclic mechanostimulation of single cells, cell clusters, cell spheroids, or organoids and may be utilized in any of a variety of biomedical applications including, without limitation, cellular engineering, cellular phenotyping, and drug discovery/screening. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/939685 |
| ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 33/10 (20130101) C08L 33/26 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/20 (20130101) C12M 25/14 (20130101) C12M 35/02 (20130101) C12M 35/04 (20130101) C12M 41/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866687 | Kodandaramaiah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V. (Munich, Germany) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Suhasa Kodandaramaiah (Minneapolis, Minnesota); Elena Taverna (Dresden, Germany); Gabriella Shull (Minneapolis, Minnesota); Wieland Huttner (Dresden, Germany) |
| ABSTRACT | Techniques are described for automated microinjection of substances, such as genetic material, into single cells in tissue samples. An example system comprises a robotic manipulator apparatus configured to hold and position a micropipette. Furthermore, the system comprises a microscope camera positioned to observe an injection site. A computing device receives image data from a microscope camera of the system, where the image data represents an image of a tissue sample. The computing device receives, via a user interface, an indication of a line traced by a user on the image of a tissue sample. In response, the computing device controls the robotic manipulator apparatus to move a tip of the micropipette along a path defined by the trajectory line. The pressure controller injects a gas into the micropipette to eject a substance out of the micropipette at one or more points along the path defined by the trajectory line. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/642986 |
| ART UNIT | 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0237 (20130101) B01L 9/54 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) C12M 23/50 (20130101) C12M 33/04 (20130101) C12M 41/08 (20130101) C12M 41/40 (20130101) C12M 41/48 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/89 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 35/109 (20130101) G01N 35/00693 (20130101) G01N 35/1002 (20130101) G01N 2035/1039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866697 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); David Benjamin Turitz Cox (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Omar O. Abudayyeh (Cambridge, Massachusetts); Bernd Zetsche (Cambridge, Massachusetts); Jonathan Strecker (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a DNA-targeting Cpf1 protein, at least one guide molecule, and at least one adenosine deaminase protein or catalytic domain thereof. |
| FILED | Friday, May 18, 2018 |
| APPL NO | 16/614549 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/62 (20130101) C12N 15/79 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 2310/533 (20130101) Enzymes C12Y 305/04004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866708 | Kim |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Tae Hoon Kim (Plano, Texas) |
| ABSTRACT | The disclosure provides for eRNA-targeted transcriptional reprogramming through targeted reduction of eRNAs for a clinically relevant gene, TNFSF10, resulting in a selective control of interferon-induced apoptosis. A method of inhibiting a TNFSF10 gene expression in a human cell is disclosed. The methods described herein comprise contacting the human cell with a single-stranded antisense compound consisting of the sequence selected from a set of SEQ ID NOs: disclosed herein, wherein the antisense compound targets an enhancer RNA (eRNA) transcribed from a genomic enhancer sequence or region. The eRNA is an TNFSF10 eRNA sequence comprising the nucleic acid sequence selected from the SEQ ID NOs disclosed herein which inhibits expression of the TNFSF10 gene in the human cell. |
| FILED | Wednesday, October 21, 2020 |
| APPL NO | 17/076696 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) Original (OR) Class C12N 2310/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866730 | Humes et al. |
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| FUNDED BY |
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| APPLICANT(S) | SeaStar Medical, Inc. (Denver, Colorado) |
| ASSIGNEE(S) | SeaStar Medical, Inc. (Denver, Colorado) |
| INVENTOR(S) | H. David Humes (Ann Arbor, Michigan); Deborah A. Buffington (Ann Arbor, Michigan); Christopher J. Pino (Saline, Michigan) |
| ABSTRACT | The present invention relates to a cytopheretic cartridge for use in treating and/or preventing inflammatory conditions within a subject and to related methods. More particularly, the invention relates to a cytopheretic cartridge that includes a housing and, disposed within the housing, a solid support capable of sequestering activated leukocytes and/or platelets. |
| FILED | Monday, September 13, 2021 |
| APPL NO | 17/473176 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1698 (20130101) A61M 1/3672 (20130101) A61M 1/3675 (20130101) A61M 1/3679 (20130101) A61M 2202/0427 (20130101) A61M 2202/0439 (20130101) Separation B01D 63/02 (20130101) B01D 2313/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866733 | Soto-Gutierrez et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Alejandro Soto-Gutierrez (Pittsburgh, Pennsylvania); Alexandra Sylvie Collin de l'Hortet (Pittsburgh, Pennsylvania); Kan Handa (Pittsburgh, Pennsylvania); Jorge Guzman Lepe (Pittsburgh, Pennsylvania); Yang Wang (Pittsburgh, Pennsylvania); Kazuki Takeishi (Pittsburgh, Pennsylvania); Ira Jacob Fox (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods are disclosed herein for efficiently generating human induced pluripotent stem cells (iPSC) containing a nucleic acid including a doxycycline promoter operably linked to a nucleic acid encoding Cas9. These methods include transfecting a human somatic cell with a nucleic acid molecule comprising a doxycycline promoter operably linked to a nucleic acid encoding a Cas9, and constitutive promoter operably linked to a tetracycline responsive element and inducing the somatic cell to form an iPSC, thereby producing an iPSC that can undergo CRISPR/Cas9-mediated recombination at a high efficiency. The human iPSC, or a cell differentiated therefrom, is cultured in the presence of doxycycline to induce expression of the Cas9. These cells can then be used to target in any gene of interest by introducing nucleic acids encoding sgRNAs. Induced pluripotent stem cells produced by these methods are also disclosed. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 16/322087 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2320/12 (20130101) C12N 2330/51 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/608 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866736 | Mootha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Vamsi Mootha (Boston, Massachusetts); Denis Titov (Boston, Massachusetts); Valentin Cracan (Boston, Massachusetts); Zenon Grabarek (Boston, Massachusetts) |
| ABSTRACT | The invention encompasses water-forming NADH and NADPH oxidases and the use of these enzymes to treat mammalian diseases or conditions associated with an elevated NADH/NAD+ ratio or NADPH/NADP+ ratio. Such pathologies include disorders caused by one or more defects in the mitochondrial respiratory chain, glucose metabolism disorders, cancers associated with reductive stress, and aging. The invention also provides a research tool for investigating the effect of exogenous water-forming NADH or NADPH oxidases on the metabolism of a mammalian cell, such as a human cell, and for elucidating the role of respiratory chain proteins in mitochondrial disorders. |
| FILED | Monday, August 01, 2016 |
| APPL NO | 15/749218 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/162 (20130101) A61K 38/1709 (20130101) A61K 38/1774 (20130101) A61K 47/18 (20130101) A61K 47/42 (20130101) A61K 47/66 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) Peptides C07K 14/195 (20130101) C07K 14/335 (20130101) C07K 2319/07 (20130101) C07K 2319/43 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/0602 (20130101) C12N 9/0036 (20130101) Original (OR) Class C12N 15/52 (20130101) C12N 15/62 (20130101) C12N 15/85 (20130101) C12N 15/113 (20130101) Enzymes C12Y 106/03001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866774 | Ririe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BioFire Diagnostics, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | BioFire Diagnostics, LLC (Salt Lake City, Utah) |
| INVENTOR(S) | Kirk M. Ririe (Salt Lake City, Utah); Mark Aaron Poritz (Salt Lake City, Utah); Randy P. Rasmussen (Salt Lake City, Utah) |
| ABSTRACT | Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analyses include high density nucleic acid amplification and detection and immuno-PCR. |
| FILED | Tuesday, December 08, 2020 |
| APPL NO | 17/114622 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/502738 (20130101) B01L 7/52 (20130101) B01L 2200/10 (20130101) B01L 2200/16 (20130101) B01L 2300/044 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/1822 (20130101) B01L 2400/049 (20130101) B01L 2400/0481 (20130101) B01L 2400/0655 (20130101) Apparatus for Enzymology or Microbiology; C12M 33/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866779 | Giese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Roger W. Giese (Hanover, Massachusetts); Poguang Wang (Westborough, Massachusetts) |
| ABSTRACT | MALDI-MS operated slightly under matrix storm conditions with a high-energy-transfer, acidic matrix, or these conditions with a high sample to matrix ratio, can with ultrasensitivity detect a nucleobase, modified or canonical, of a nucleic acid species as a jettisoned, protonated molecule. |
| FILED | Thursday, February 28, 2019 |
| APPL NO | 16/961074 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6872 (20130101) Original (OR) Class C12Q 2523/313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866781 | Xie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Xiaoliang Sunney Xie (Lexington, Massachusetts); Katsuyuki Shiroguchi (Arlington, Massachusetts); Peter A. Sims (Cambridge, Massachusetts); Tony Z. Jia (Cambridge, Massachusetts) |
| ABSTRACT | Methods and compositions for digital profiling of nucleic acid sequences present in a sample are provided. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/320361 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) C12N 2320/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6853 (20130101) C12Q 1/6853 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2525/131 (20130101) C12Q 2525/301 (20130101) C12Q 2537/16 (20130101) C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866783 | Wheeler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Thurman Wheeler (Boston, Massachusetts); Xandra O. Breakefield (Newton Center, Massachusetts); Leonora Balaj (Charlestown, Massachusetts) |
| ABSTRACT | Described herein are methods for diagnosing and monitoring subjects with diseases associated with aberrant splicing, based upon detecting properly spliced isoforms and mis-spliced isoforms in a urine sample from the subject. |
| FILED | Friday, July 21, 2017 |
| APPL NO | 16/318658 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6865 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866784 | Sanford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jeremy Sanford (Santa Cruz, California); Timothy Steme-Weiler (Santa Cruz, California) |
| ABSTRACT | Compounds and methods for regulation of exonic splicing enhancers and exonic splicing silencers. Compounds include polynucleotides targeted to aberrant exonic splicing enhancers and exonic splicing silencers. Compounds and methods for the diagnosis of diseases and conditions associated with aberrant exonic splicing enhancers and exonic splicing silencers. Methods for identifying splicing-sensitive disease mutations, and functional RNA elements as targets for amelioration of aberrant pre-mRNA splicing. |
| FILED | Friday, April 23, 2021 |
| APPL NO | 17/238551 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2320/33 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866785 | Ippolito et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Gregory C. Ippolito (Austin, Texas); Jonathan R. Mcdaniel (Austin, Texas); William N. Voss (Austin, Texas); George Georgiou (Austin, Texas) |
| ABSTRACT | Methods are provided for identifying tumor-specific antibodies and/or T-cell receptors by paired mRNA sequencing from individual immune cells in sentinel lymph nodes and comparison of these sequences with corresponding mass spectroscopy data from a subject having a cancer. Novel tumor-specific antibodies (e.g., NY-ESO-1-binding antibodies) are also provided. |
| FILED | Monday, October 29, 2018 |
| APPL NO | 16/759371 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/3069 (20130101) C07K 2317/24 (20130101) C07K 2317/565 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) C12Q 1/6886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866788 | Bagchi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Anindya Bagchi (San Diego, California); Ashutosh Tiwari (San Diego, California) |
| ABSTRACT | Disclosed herein are methods of diagnosing and treating MYC-driven cancers by detecting a PVT1 splice variant in a biological sample from a subject. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 17/053328 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867602 | Knox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Wayne H. Knox (Rochester, New York); Gregory Madejski (Albion, New York); James Lionel McGrath (Rochester, New York) |
| ABSTRACT | A device, system and method for the detection and screening of plastic microparticles in a sample is disclosed. A nanoporous silicon nitride membrane is used to entrap plastic microparticles contained in the sample. The sample may be a water sample, an air sample, or other liquid or gas sample. The entrapped plastic microparticles are then heated or otherwise processed on the nanoporous silicon nitride membrane. An imaging system observes the nanoporous silicon nitride membrane with the entrapped plastic microparticles to determine the type and quantity of the various plastic microparticles that are entrapped on the membrane. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579515 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/20 (20130101) B01D 71/02 (20130101) B01D 2311/103 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0612 (20130101) Original (OR) Class G01N 2015/0681 (20130101) G01N 2015/0693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867627 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Quing Zhu (St. Louis, Missouri); Hamed Vavadi (St. Louis, Missouri); Atahar Mostafa (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); The University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Quing Zhu (St. Louis, Missouri); Hamed Vavadi (St. Louis, Missouri); Atahar Mostafa (St. Louis, Missouri) |
| ABSTRACT | A compact diffuse optical tomography system for generating a functional image of a lesion region is provided. The system includes a source subsystem, a probe, a detection subsystem, and a computing device. The source subsystem includes laser diodes and a laser diode driver board. The probe is configured to emit the optical waves generated by the source subsystem toward the lesion region and detect optical waves reflected by the lesion region. The detection subsystem includes a miniaturized detection board and a miniaturized data acquisition board. The miniaturized detection board includes a photomultiplier tube configured to convert the optical waves detected by the probe to electrical signals. The miniaturized data acquisition board is configured to convert electrical signals outputted by the miniaturized detection board to digital signals. The computing device is configured to receive the digital signals, reconstruct the functional image, and display the functional image. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 16/599322 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/636 (20130101) G01N 21/4795 (20130101) Original (OR) Class G01N 2021/1787 (20130101) G01N 2201/0612 (20130101) Image Data Processing or Generation, in General G06T 11/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867644 | Ros et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Alexandra Ros (Phoenix, Arizona); Daihyun Kim (Mesa, Arizona); Austin Echelmeier (Tempe, Arizona); Jorvani Cruz Villarreal (Tempe, Arizona); Ana Egatz-Gomez (Phoenix, Arizona); Sebastian Quintana (Phoenix, Arizona) |
| ABSTRACT | Methods and systems are provided for serial femtosecond crystallography for reducing the vast amount of waste of injected crystals practiced with traditional continuous flow injections. A micrometer-scale 3-D printed water-in-oil droplet generator device includes an oil phase inlet channel, an aqueous phase inlet channel, a droplet flow outlet channel, and two embedded non-contact electrodes. The inlet and outlet channels are connected internally at a junction. The electrodes comprise gallium metal injected within the 3-D printed device. Voltage across the electrodes generates water-in-oil droplets, determines a rate for a series of droplets, or triggers a phase shift in the droplets. An external trigger generates the droplets based on the frequency of an XFEL utilized in droplet detection, thereby synchronizing a series of droplets with x-ray pulses for efficient crystal detection. The generated droplets can be coupled to an SFX with XFEL experiment compatible with common liquid injector such as a GDVN. |
| FILED | Thursday, April 01, 2021 |
| APPL NO | 17/220357 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0241 (20130101) B01L 3/50273 (20130101) B01L 2300/0867 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20025 (20130101) Original (OR) Class G01N 2223/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867676 | Potyrailo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Radislav Alexandrovich Potyrailo (Niskayuna, New York); Richard St. Pierre (Clifton Park, New York); Bruce Courtney Amm (Clifton Park, New York) |
| ABSTRACT | A multi-gas sensing system includes a sensing circuit comprising one or more sensing elements. Each sensing element includes a sensing material configured to detect at least one gas analyte. A management circuit is configured to excite the sensing elements with an alternating current at at least one predetermined frequency. The management circuit measures one or more electrical responses of the sensing elements responsive to exciting the sensing elements with the alternating current. The management circuit determines one or more characteristics of the sensing circuit. One or more processors receive the electrical responses of the sensing elements and the characteristics of the sensing circuit. The one or more processors determine a concentration of the at least one gas analyte based on the electrical responses of the sensing elements and the characteristics of the sensing circuit. |
| FILED | Monday, March 09, 2020 |
| APPL NO | 16/812613 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0006 (20130101) G01N 33/0031 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867684 | Ouyang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Zheng Ouyang (West Lafayette, Indiana); He Wang (West Lafayette, Indiana); Nicholas E. Manicke (West Lafayette, Indiana); Robert Graham Cooks (West Lafayette, Indiana); Qian Yang (West Lafayette, Indiana); Jiangjiang Liu (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to a sample dispenser including an internal standard and methods of use thereof. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/584100 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 1/28 (20130101) G01N 1/286 (20130101) G01N 33/491 (20130101) G01N 33/492 (20130101) Original (OR) Class G01N 33/48714 (20130101) G01N 33/48785 (20130101) G01N 2001/2893 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0009 (20130101) H01J 49/16 (20130101) H01J 49/0027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867693 | Kamei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Daniel Takashi Kamei (Monterey Park, California); Maie A. St. John (Los Angeles, California); Zachary D. Taylor (Los Angeles, California); Daniel William Bradbury (Los Angeles, California); Ashley Elizabeth Kita (Los Angeles, California) |
| ABSTRACT | Devices and methods are provided for the detection of CSF in a biological sample. In certain embodiments the device is a lateral flow device comprising: a porous substrate; a sample addition zone disposed on or in said porous substrate; a detection zone disposed on or in said porous substrate where said detection zone comprises at least a first test line (T1) and a second test line (T2) each test line comprising binding moieties that bind a complex formed between beta-trace protein (βTP) and an indicator attached to a βTP binding molecule; wherein said porous substrate defines a flow path through which a sample applied to the sample addition zone flows under capillary action away from said sample addition zone into said detection zone; and wherein said first test line (T1) and said second test line (T2) are is configured so that either no test line signal or just a signal at the first test line (T1) is detectable when βTP concentration in a sample applied to said device is lower than the βTP level indicative of a CSF leak; and said second test line (T2) is configured so that a signal is detectable at said second test line when βTP concentration in a sample applied to said device is greater than the βTP level indicative of a CSF leak. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/530336 |
| ART UNIT | 1799 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54386 (20130101) Original (OR) Class G01N 2333/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867696 | Schwartz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CELL IDX, INC. (San Diego, California) |
| ASSIGNEE(S) | CELL IDX, INC. (San Diego, California) |
| INVENTOR(S) | David A. Schwartz (Encinitas, California) |
| ABSTRACT | The present disclosure provides high-performance immunoreagents for use in a variety of immunologic assays and other related techniques. The immunoreagents comprise a primary antibody and a bridging antigen, wherein the bridging antigen is recognized by a detectable secondary antibody with high affinity. Also provided are compositions comprising panels of immunoreagents specific for multiple different target antigens and compositions comprising pairs of primary immunoreagents and their complementary detectable secondary antibodies. The paired primary immunoreagents and secondary antibodies are useful in a variety of immunologic assays, particularly in highly multiplexed assays, where the structure of the bridging antigen is varied in tandem with variation in the detectable secondary antibody, such that a multiplicity of immunoreagents are provided that are capable of simultaneously detecting a multiplicity of target antigens in a single assay. Also provided are kits comprising the immunoreagents, methods of immunologic assay using the immunoreagents of the disclosure, and methods of preparation of the immunoreagents. |
| FILED | Saturday, February 06, 2016 |
| APPL NO | 15/017626 |
| ART UNIT | 1677 — Optics |
| CURRENT CPC | Peptides C07K 16/00 (20130101) C07K 16/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) G01N 33/535 (20130101) G01N 33/574 (20130101) G01N 33/5743 (20130101) Original (OR) Class G01N 33/54306 (20130101) G01N 2474/20 (20210801) G01N 2800/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867701 | Stappenbeck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thaddeus Stappenbeck (St. Louis, Missouri); Ta-Chiang Liu (St. Louis, Missouri); Kelli VanDussen (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Thaddeus Stappenbeck (St. Louis, Missouri); Ta-Chiang Liu (St. Louis, Missouri); Kelli VanDussen (St. Louis, Missouri) |
| ABSTRACT | The present disclosure provides methods for classifying a cell as abnormal based on HD5 protein detection as well as methods for predicting prognosis of a subject with Crohn's disease based on HD5 protein detection. |
| FILED | Thursday, April 27, 2017 |
| APPL NO | 16/097104 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/4723 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2800/52 (20130101) G01N 2800/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867892 | Pathak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Arvind Pathak (Baltimore, Maryland); Nitish Thakor (Clarksville, Maryland); Janaka Senarathna (Baltimore, Maryland); Hang Yu (Baltimore, Maryland) |
| ABSTRACT | An embodiment in accordance with the present invention provides a miniature microscope capable of performing in vivo, real-time imaging of multiple organ sites in awake and behaving animals (e.g. rodents). A microscope according to the present invention includes multiple optical contrast mechanisms (i.e. contrast arising from neural, hemodynamic and other physiological components). Exemplary contrast mechanisms include, but are not limited to fluorescence, hemoglobin level, deoxyhemoglobin level, and blood flow. The microscope is fully adaptable to in vitro and ex vivo imaging, can be customized to concurrently image at variable magnifications, conduct optogenetic/electrical/chemical stimulations, drug delivery, microdialysis, accompanied by electrical signal recording, wireless image transmission and charging. |
| FILED | Friday, July 06, 2018 |
| APPL NO | 16/628859 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/0042 (20130101) A61B 5/0071 (20130101) A61B 5/0077 (20130101) A61B 5/1455 (20130101) A61B 5/6814 (20130101) Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) G02B 21/16 (20130101) Original (OR) Class G02B 21/025 (20130101) G02B 21/365 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 47/19 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11869191 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ning Ma (Oakland, California); Michelle Digman (Oakland, California); Hongtao Chen (Oakland, California) |
| ABSTRACT | A system for determining the viability of an embryo comprises an imaging device, an excitation device configured to direct an excitation energy at an embryo, a controller communicatively connected to the imaging device and the excitation device, configured to drive the excitation device and collect images from the imaging device at an imaging frequency, a processor performing steps comprising acquiring a set of images from the imaging device, performing a Fourier Transformation to generate a set of phasor coordinates, computing a D-trajectory, computing a set of values of additional parameters, comparing the set of values to a set of stored values related to embryos of known viability, and calculating a viability index factor of the embryo from the set of values and the set of stored values. Methods of calculating embryo viability and determining one or more properties of a tissue are also described. |
| FILED | Monday, July 11, 2022 |
| APPL NO | 17/811743 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) G01N 33/5005 (20130101) Image Data Processing or Generation, in General G06T 7/0014 (20130101) Original (OR) Class G06T 7/66 (20170101) G06T 2207/10056 (20130101) G06T 2207/10064 (20130101) G06T 2207/20056 (20130101) G06T 2207/30024 (20130101) G06T 2207/30044 (20130101) Pictorial Communication, e.g Television H04N 23/56 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11869633 | Iyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ravishankar Krishnan Iyer (Champaign, Illinois); Arjun Prasanna Athreya (Urbana, Illinois); Richard Merle Weinshilboum (Rochester, Minnesota); Liewei Wang (Rochester, Minnesota); William Victor Bobo (Rochester, Minnesota); Mark Andrew Frye (Rochester, Minnesota) |
| ABSTRACT | The present disclosure provides methods for accurately predicting the dynamics of symptom response to drugs or other interventions for the treatment of major depressive disorder or other psychological conditions. These methods can allow for a shortening of the time period necessary for the evaluation of a drug or other therapeutic intervention. These predictive methods are based on measured and/or self-reported symptom severity measures at two or more points in time. These measures are then discretized into symptom classes (e.g., low, moderate, severe) and the symptom classes are then applied to the predictive model to predict the progression of symptoms and/or the effectiveness of a drug or other therapeutic intervention. The predictive methods may be augmented by metabolomics data, genomics data, or other objective measures taken from a patient, allowing the use of objective physiological measures to diagnosis and treat psychological conditions heretofore diagnosed and assessed using only subjective, self-reported measures. |
| FILED | Friday, December 14, 2018 |
| APPL NO | 16/221073 |
| ART UNIT | 1671 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 40/00 (20190201) Original (OR) Class G16B 40/20 (20190201) G16B 40/30 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/30 (20190201) G16C 20/70 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11864896 | Durkee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aptima, Inc. (Woburn, Massachusetts) |
| ASSIGNEE(S) | Aptima, Inc. (Woburn, Massachusetts) |
| INVENTOR(S) | Kevin Durkee (Carmel, Indiana); Scott Pappada (Fairborn, Ohio); Andres Ortiz (Simi Valley, California); William DePriest (Dayton, Ohio); John Feeney (Beavercreek, Ohio); Alexandra Geyer (Winchester, Massachusetts); Seamus Sullivan (Oakwood, Ohio); Sterling Wiggins (Yellow Springs, Ohio) |
| ABSTRACT | Computer based systems and methods for estimating a user state are disclosed. In some embodiments, the methods comprise inputting a first input at an intermittent interval and a second input at a frequent interval into a user state estimation model to estimate the user state. In some embodiments, the first inputs are enhanced by injecting a noise input to create a plurality of enhanced first inputs whereby the plurality of enhance first inputs correspond to the plurality of second inputs at the frequent interval. In some embodiments, the first input comprises a self-reported input and the second inputs comprise a physiological input, a performance input or a situational input. In some embodiments, a machine learning algorithm creates the state estimation model. In some embodiments, the state estimation model estimates a future user state. In some embodiments, a computer based system for estimating a user state is provided. |
| FILED | Monday, March 25, 2019 |
| APPL NO | 16/362745 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) Original (OR) Class A61B 5/316 (20210101) A61B 5/369 (20210101) A61B 5/7203 (20130101) A61B 5/7246 (20130101) A61B 5/7267 (20130101) A61B 5/7475 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/28 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865025 | Tomblin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wichita State University (Wichita, Kansas) |
| ASSIGNEE(S) | Wichita State University (Wichita, Kansas) |
| INVENTOR(S) | John S. Tomblin (Wichita, Kansas); Thomas Aldag (Wichita, Kansas); William T. McCarvill (Cottonwood Heights, Utah); Kimberly M. Reuter (Wichita, Kansas); Joel D. White (Wichita, Kansas); Andrea C. Meyer (Bel Aire, Kansas) |
| ABSTRACT | Methods of using fiber-reinforced composite articles useful in supporting or immobilizing an injured body part is disclosed. The composite is a multi-layer, flexible precursor including fiber reinforcement plies, which can be rapidly cured into a rigid body using a thermosetting resin. Methods of making and using the same are also disclosed, along with kits containing such composite articles. |
| FILED | Friday, March 18, 2022 |
| APPL NO | 17/698398 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/01 (20130101) A61F 5/0585 (20130101) A61F 5/05825 (20130101) Original (OR) Class A61F 5/05841 (20130101) A61F 13/04 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/08 (20130101) A61L 15/12 (20130101) A61L 15/12 (20130101) A61L 15/12 (20130101) A61L 15/14 (20130101) A61L 15/125 (20130101) A61L 15/125 (20130101) Compositions of Macromolecular Compounds C08L 33/10 (20130101) C08L 33/10 (20130101) C08L 35/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865111 | Bohmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas); The Government of The United States, as represented by The Secretary of the Army (Fort Detrick, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | Southwest Research Institute (San Antonio, Texas); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland); The Government of the United States, as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Jonathan A. Bohmann (San Antonio, Texas); Nadean M. Gutierrez (Devine, Texas); Joseph A. McDonough (Helotes, Texas); Robert Francis Campbell (Edgemere, Maryland); Michael Gordon Joyce (Silver Spring, Maryland); Rekha Panchal (Fort Detrick, Maryland); Rajeshwer Sankhala (Bethesda, Maryland); Allen Duplantier (Stafford, Virginia) |
| ABSTRACT | Antiviral drugs targeting the N-terminal domain (NTD) of the spike receptor binding domain (RBD) and methods of treating a subject suffering from coronavirus. |
| FILED | Thursday, August 11, 2022 |
| APPL NO | 17/819178 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/445 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865536 | Goyal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Girija Goyal (Cambridge, Massachusetts); Donald E. Ingber (Boston, Massachusetts) |
| ABSTRACT | An organ-on-a-chip microfluidic device is disclosed that mimics a human lymph node and/or human lymphoid tissue. The device can include cells from human blood and lymphatic tissue, include an extracellular matrix for the development of immune system components, and provide for the perfusion of fluids and solids resembling blood and lymphatic fluid within micrometer sized channels. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 17/730615 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/28 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) A61P 35/00 (20180101) A61P 37/04 (20180101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Original (OR) Class B01L 2300/0861 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/069 (20130101) C12N 5/0635 (20130101) C12N 5/0636 (20130101) C12N 5/0645 (20130101) C12N 5/0651 (20130101) C12N 5/0693 (20130101) C12N 2531/00 (20130101) C12N 2533/52 (20130101) C12N 2533/54 (20130101) C12N 2533/90 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865656 | Deluca et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Michael J. Deluca (Norristown, Pennsylvania); Matthew H. Cawthorne (Wayne, Pennsylvania); Howard T. Rolleston (Glen Mills, Pennsylvania) |
| ABSTRACT | A method for repairing a crack in a structure includes mounting a manifold to the structure around the crack. The structure has a nonplanar surface contour that surrounds the crack. The manifold has a base portion, a cover portion, and a plug. The base portion has a grip surface configured to conform to the nonplanar surface contour of the structure. The cover portion is connected to the base portion, and has an injection port and a vent port in fluid communication with a channel aligned to the crack. The injection port transfers a bonding material into and out of the channel. The plug closes and opens the vent port. The method includes filling the channel with the bonding material to direct the bonding material into the crack, and draining the bonding material from the manifold. |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 17/677036 |
| ART UNIT | 1748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/002 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 6/04 (20130101) Original (OR) Class Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 73/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865723 | Goldfarb et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Michael Goldfarb (Nashville, Tennessee); Andres Martinez-Guerra (Nashville, Tennessee); Brian Lawson (Nashville, Tennessee) |
| ABSTRACT | An exemplary robotic system includes a plurality of controllable joints and a controller. An exemplary control method provides for controlling the controllable joints by the controller. The control method provides for determining a configuration space for the robotic system and determining a reference movement path within the configuration space. The control method then provides for assigning a plurality of streamlines in the configuration space to yield a flow field based on the reference movement path. The control method then provides for measuring actual velocity vectors of the robotic system in the configuration space. The control method then provides for determining an error velocity vector based on a difference between the actual velocity vector and the desired velocity vector given by the flow field corresponding to the current robot configuration. The control method then provides for applying a total control vector at the plurality of controllable joints, by the controller, based on the error velocity vector. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 17/040075 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) B25J 9/1633 (20130101) B25J 9/1651 (20130101) B25J 9/1653 (20130101) B25J 9/1664 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865745 | Shields |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Garry E. Shields (Ashburn, Virginia) |
| ABSTRACT | Systems and methods for designing and producing articles using augmented reality apparatus are provided. The articles may incorporate commercially-available off-the-shelf (COTS) components such as motors, power supplies, and/or propulsion systems for use as vehicles or vessels. The articles may also incorporate modular components, such as storage and/or building components. Methods and kits for producing the articles are also provided. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 16/822633 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/3842 (20130101) Original (OR) Class B29C 39/10 (20130101) B29C 44/12 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2075/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866079 | Notomista et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Gennaro Notomista (Atlanta, Georgia); Magnus B. Egerstedt (Atlanta, Georgia); Yousef A. Emam (Atlanta, Georgia) |
| ABSTRACT | An exemplary embodiment of the present disclosure provides a robot comprising a body, a processor, and a memory. The memory further comprising instructions that, when executed by the processor cause the body to engage a first wire to support the robot from the first wire, traverse the first wire, engage a second wire simultaneously while engaging the first wire, the second wire branching from the first wire, then after engaging the second wire, disengage the first wire and traverse the second wire. |
| FILED | Tuesday, February 16, 2021 |
| APPL NO | 17/176927 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/04 (20130101) B25J 9/126 (20130101) Railway Systems; Equipment Therefor Not Otherwise Provided for B61B 3/02 (20130101) Guiding Railway Traffic; Ensuring the Safety of Railway Traffic B61L 3/006 (20130101) Original (OR) Class B61L 5/023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866148 | Gross et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SciMax Technologies, LLC (Long Beach, New York) |
| ASSIGNEE(S) | SCIMAX TECHNOLOGIES, LLC (Long Beach, New York) |
| INVENTOR(S) | Max Gross (Long Beach, New York); Joseph Bruno (Long Beach, New York) |
| ABSTRACT | A floor panel for installation in an aircraft includes a plurality of thermoplastic C-shaped stringers, a consolidated thermoplastic deltoid filler, a thermoplastic upper facing sheet, and a thermoplastic lower facing sheet. The stringers are disposed in a parallel arrangement with one another. The deltoid filler is disposed within a longitudinally-extending notch defined by a pair of adjacent stringers. The upper facing sheet covers an upper surface of the stringers and the deltoid filler. The lower facing sheet covers a lower surface of the stringers and the deltoid filler. The stringers, the deltoid filler, and the upper and lower facing sheets are integrally consolidated forming a unitary construction. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/008467 |
| ART UNIT | 1748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/02 (20130101) Aeroplanes; Helicopters B64C 1/18 (20130101) Original (OR) Class B64C 2001/0072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866168 | Cooper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Neil E. Cooper (Sterling Heights, Michigan); Eric S. Paternoster (Saint Clair Shores, Michigan); Jason A. Schrader (Washington, Michigan); Gary L. Bronstetter (Macomb, Michigan) |
| ABSTRACT | An enclosure for a UAS includes a housing having a base and a plurality of sidewalls coupled to the base, a motive apparatus coupled to the housing, a platform coupled to the motive apparatus, and a plurality of lids pivotably coupled to the sidewalls and the platform. The platform and the plurality of lids move collectively under control of the motive apparatus (e.g., a linear actuator). Driving the motive apparatus in a first direction causes the platform to raise from a stowed position toward a deployed position and causes each of the plurality of lids to pivot from a closed position toward an open position. Conversely, driving the motive apparatus in a second direction opposite the first direction causes the platform to lower from the deployed position toward the stowed position and causes each of the plurality of lids to pivot from the open position toward the closed position. |
| FILED | Monday, September 27, 2021 |
| APPL NO | 17/485633 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Original (OR) Class Unmanned aerial vehicles [UAV]; equipment therefor B64U 50/19 (20230101) B64U 80/70 (20230101) B64U 2201/10 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866205 | Hefner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Levi Charles Hefner (Dallas, Texas); Dakota Charles Easley (Dallas, Texas) |
| ABSTRACT | An unmanned aircraft system operable for wing-borne lift in a flying wing orientation. The unmanned aircraft system includes an airframe having a leading edge, a trailing edge, first and second wingtips and a root chord. The airframe has an airfoil cross-section along chord stations thereof. A thrust array is coupled to the airframe including first and second motor mounts coupled to the leading edge respectively between the root chord and the first and second wingtips. The motor mounts each have first and second propulsion assemblies coupled to respective first and second distal ends thereof. The motor mounts each have a flight configuration substantially perpendicular with the leading edge forming a two-dimensional distributed thrust array such that the airframe extends outboard of the first and second motor mounts. The unmanned aircraft system includes an electric power system and a flight control system that are operably associated with the thrust array. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 17/714096 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 11/46 (20130101) B64C 29/02 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/26 (20130101) B64D 2027/262 (20130101) Unmanned aerial vehicles [UAV]; equipment therefor B64U 10/25 (20230101) B64U 30/20 (20230101) B64U 30/293 (20230101) Original (OR) Class B64U 50/19 (20230101) B64U 80/00 (20230101) B64U 2201/10 (20230101) B64U 2201/20 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866337 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Jiaxing Huang (Wilmette, Illinois); Luke Clyde Oak Prestowitz (Evanston, Illinois) |
| ABSTRACT | Provided are methods for synthesizing a graphene gel. In embodiments, such a method comprises flowing a graphene oxide composition comprising graphene oxide and a solvent, the solvent having a boiling point higher than pure water, through a reaction chamber under conditions to deoxygenate the graphene oxide and induce gelation to form a graphene gel suspended in the solvent and flowing through the reaction chamber. |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 17/846293 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/194 (20170801) C01B 32/198 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2006/40 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866438 | Haddach |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pimera, Inc. (San Diego, California) |
| ASSIGNEE(S) | PIMERA, INC. (San Diego, California) |
| INVENTOR(S) | Mustapha Haddach (San Diego, California) |
| ABSTRACT | Generally, the present invention provides novel quinolone and 5H-1,5,7,11b-tetraaza-benzo[c]fluoren-6-one compounds and pharmaceutical composition thereof which may inhibit cell proliferation and/or induce cell apoptosis. The present invention also provides methods of preparing such compounds and compositions, and methods of making and using the same. |
| FILED | Wednesday, March 17, 2021 |
| APPL NO | 17/204459 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4353 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) C07D 471/14 (20130101) Original (OR) Class C07D 471/22 (20130101) C07D 487/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866493 | Xie |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | East Tennessee State University Research Foundation (Johnson City, Tennessee) |
| ASSIGNEE(S) | EAST TENNESSEE STATE UNIVERSITY RESEARCH FOUNDATION (Johnson City, Tennessee) |
| INVENTOR(S) | Qian Xie (Johnson City, Tennessee) |
| ABSTRACT | A single-chain variable fragment (ScFv) derived from anti-c-Met monoclonal antibody MetMAb that specifically binds to c-Met receptor is provided. Also provided are chimeric antigen receptor (CAR) vectors including the ScFv, human T cells transduced with the disclosed CAR vectors, pharmaceutical compositions including the CAR T cells, ScFv fusion proteins, and methods of treating a c-Met-positive cancer or a cancer characterized by overexpression of c-Met in a subject in need thereof by administering an effective amount of the disclosed CAR T cells. |
| FILED | Monday, November 02, 2020 |
| APPL NO | 17/086839 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/28 (20130101) Original (OR) Class C07K 2317/622 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866560 | Ghiassi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Kamran B Ghiassi (Palmdale, California); Neil D Redeker (Lancaster, California); Alexander T Lonnecker (Lancaster, California); Jayden N. Glover (Fort Collins, Colorado) |
| ABSTRACT | The present invention relates to a microfluidic flow process for making monomers, monomers made by such processes, and methods of using such monomers. In such process, microfluidic reaction technology is used to synthesize cyanation reaction products orders of magnitude faster than is possible in batch and continuous syntheses. The aforementioned process does require strictly regulated, highly toxic cyanogen chloride. Thus the aforementioned process is more economically efficient and reduces the environmental impact of thermosetting resin monomer production, and produces thermosetting resin monomers in greater purity than obtained through typical processes. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/705534 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0093 (20130101) Acyclic or Carbocyclic Compounds C07C 261/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/065 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/243 (20210501) Original (OR) Class C08J 5/244 (20210501) C08J 2379/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866695 | Ismagilov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Rustem F. Ismagilov (Altadena, California); Erik Jue (Pasadena, California); Daan Witters (San Diego, California) |
| ABSTRACT | Methods and systems and related compositions for separating through a solid matrix a mixture comprising a nucleic acid in a concentration of 1 μM or less, together with a target compound having a water solubility equal to or greater than 0.001 g per 100 mL, which can be used for managing fluid flow, biochemical reactions and purification of the nucleic acid or other target analytes. The method comprises contacting the solid matrix with a target compound removing agent having a water solubility equal to or less than 0.05 g per 100 mL at 25° C. at 1 atm pressure with water having a solubility in the removing agent of less than 10 g per 100 mL at 25° C. at 1 atm pressure, the contacting performed to remove the target compound from the solid matrix. |
| FILED | Tuesday, December 22, 2020 |
| APPL NO | 17/131449 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) Original (OR) Class C12N 15/1013 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866699 | Lajoie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Marc Joseph Lajoie (Seattle, Washington); Elizabeth Erin Gray (Seattle, Washington); Neil P. King (Seattle, Washington); Daniel Brewster Stetson (Seattle, Washington); David Baker (Seattle, Washington); Katherine DaPron (Seattle, Washington) |
| ABSTRACT | The application discloses multimeric assemblies packaging one or more active component and their use to carry out nucleic acid regulation or gene editing. |
| FILED | Monday, February 12, 2018 |
| APPL NO | 16/476917 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/85 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2521/301 (20130101) Enzymes C12Y 301/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866730 | Humes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SeaStar Medical, Inc. (Denver, Colorado) |
| ASSIGNEE(S) | SeaStar Medical, Inc. (Denver, Colorado) |
| INVENTOR(S) | H. David Humes (Ann Arbor, Michigan); Deborah A. Buffington (Ann Arbor, Michigan); Christopher J. Pino (Saline, Michigan) |
| ABSTRACT | The present invention relates to a cytopheretic cartridge for use in treating and/or preventing inflammatory conditions within a subject and to related methods. More particularly, the invention relates to a cytopheretic cartridge that includes a housing and, disposed within the housing, a solid support capable of sequestering activated leukocytes and/or platelets. |
| FILED | Monday, September 13, 2021 |
| APPL NO | 17/473176 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/1698 (20130101) A61M 1/3672 (20130101) A61M 1/3675 (20130101) A61M 1/3679 (20130101) A61M 2202/0427 (20130101) A61M 2202/0439 (20130101) Separation B01D 63/02 (20130101) B01D 2313/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866785 | Ippolito et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Gregory C. Ippolito (Austin, Texas); Jonathan R. Mcdaniel (Austin, Texas); William N. Voss (Austin, Texas); George Georgiou (Austin, Texas) |
| ABSTRACT | Methods are provided for identifying tumor-specific antibodies and/or T-cell receptors by paired mRNA sequencing from individual immune cells in sentinel lymph nodes and comparison of these sequences with corresponding mass spectroscopy data from a subject having a cancer. Novel tumor-specific antibodies (e.g., NY-ESO-1-binding antibodies) are also provided. |
| FILED | Monday, October 29, 2018 |
| APPL NO | 16/759371 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/3069 (20130101) C07K 2317/24 (20130101) C07K 2317/565 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) C12Q 1/6886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866788 | Bagchi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Anindya Bagchi (San Diego, California); Ashutosh Tiwari (San Diego, California) |
| ABSTRACT | Disclosed herein are methods of diagnosing and treating MYC-driven cancers by detecting a PVT1 splice variant in a biological sample from a subject. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 17/053328 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867208 | Weiland |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Christopher J. Weiland (King George, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Christopher J. Weiland (King George, Virginia) |
| ABSTRACT | A method is provided for producing a vortex ring in a liquid medium. The method includes concatenating pairs of insulated anode and cathode rings into a stack; inserting the stack into a vertically oriented chamber; disposing a cylindrical cavity below the chamber; inserting a piston into the cavity; connecting the chamber to the medium; and raising the piston to displace the medium while the stack produces an annular bubble that induces the vortex ring. In particular, the medium is water and the stack separates the medium into hydrogen and oxygen gas. |
| FILED | Wednesday, September 29, 2021 |
| APPL NO | 17/489438 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/009 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/2087 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867488 | Williamson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Seth L. Williamson (King George, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Seth L. Williamson (King George, Virginia) |
| ABSTRACT | From a plurality of sabots, a sabot is provided for shrouding a sub-caliber projectile to form a launch package in a gun bore for acceleration by an actuator behind the projectile. The sabot includes a forecastle, an aft bulkhead and a waist. The forecastle separates the projectile from the gun bore. The aft bulkhead abuts against the actuator. The waist connects the forecastle and the bulkhead by a radial spar that supports inner and outer flanges. The inner flange mechanically engages the projectile, and in preferred embodiments is concave. The gun bore is optimized as a pair of electromagnetic rails. |
| FILED | Friday, December 02, 2022 |
| APPL NO | 18/073899 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 14/062 (20130101) Original (OR) Class F42B 14/068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867556 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Seunghoon Han (Seoul, South Korea); Amir Arbabi (Pasadena, California); Andrei Faraon (Pasadena, California); Ehsan Arbabi (Pasadena, California) |
| ABSTRACT | A spectrometer includes a transparent substrate including a first surface and a second surface that face each other and are substantially parallel to each other; a slit provided on the first surface and through which light is incident onto the transparent substrate; a spectrum optical system including metasurface including a plurality of nanostructures that are two-dimensionally arranged and satisfy a sub-wavelength scattering condition, wherein the metasurface includes a focusing metasurface which includes first nanostructures of the plurality of nanostructures, and is configured to reflect, disperse, and focus the light incident thereon through the slit, at different angles based on respective wavelengths; and a sensor configured to receive the light from the focusing metasurface. When L is a total length of an optical path from the slit to the sensor and D is a thickness of the transparent substrate, L and D satisfy the following inequality: L/D>3. |
| FILED | Monday, September 27, 2021 |
| APPL NO | 17/486326 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0205 (20130101) G01J 3/0208 (20130101) Original (OR) Class G01J 3/0224 (20130101) G01J 3/0256 (20130101) G01J 3/0259 (20130101) G01J 3/447 (20130101) G01J 3/2803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867626 | Porter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | Regents of the Univ of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Christina Porter (Superior, Colorado); Daniel E. Adams (Thornton, Colorado); Michael Tanksalvala (Longmont, Colorado); Elisabeth Shanblatt (Boulder, Colorado); Margaret M. Murnane (Boulder, Colorado); Henry C. Kapteyn (Boulder, Colorado) |
| ABSTRACT | Apparatus and methods for complex imaging reflectometry and refractometry using at least partially coherent light. Quantitative images yield spatially-dependent, local material information about a sample of interest. These images may provide material properties such as chemical composition, the thickness of chemical layers, dopant concentrations, mixing between layers of a sample, reactions at interfaces, etc. An incident beam of VUV wavelength or shorter is scattered off of a sample and imaged at various angles, wavelengths, and/or polarizations. The power of beam is also measured. This data is used to obtain images of a sample's absolute, spatially varying, complex reflectance or transmittance, which is then used to determine spatially-resolved, depth-dependent sample material properties. |
| FILED | Monday, April 12, 2021 |
| APPL NO | 17/228178 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/33 (20130101) G01N 21/45 (20130101) G01N 21/956 (20130101) G01N 21/4788 (20130101) Original (OR) Class G01N 21/4795 (20130101) G01N 2021/335 (20130101) G01N 2021/1782 (20130101) G01N 2021/4711 (20130101) G01N 2201/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867754 | Lal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York); Christopher Batten (Ithaca, New York) |
| ABSTRACT | A system, comprising: (i) an interposer layer; (ii) a circuit layer positioned on the interposer layer and comprising a plurality of sonically-enabled pads; and (iii) an interrogator layer positioned on the circuit layer and comprising a plurality of ultrasonic transducers configured to sonically interrogate the circuit layer; wherein the sonically-enabled pads are configured to generate an electrical signal in response to sonic interrogation from the interrogator layer, if the sonically-enabled pad is functional. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/631590 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/00 (20130101) G01N 29/22 (20130101) G01N 29/225 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/303 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867891 | Hoover et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADVANCED OPTICAL TECHNOLOGIES, INC. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Advanced Optical Technologies, Inc. (Albuquerque, New Mexico) |
| INVENTOR(S) | Brian G. Hoover (Tijeras, New Mexico); Jonathan H. Turner (Albuquerque, New Mexico) |
| ABSTRACT | A polarimeter and a method of analyzing and imaging microstructural material orientation of a sample are disclosed. The polarimeter, which is a partial Mueller-matrix polarimeter (pMMP), accesses multiple independent polarization channels by employing two independent polarization modulators configured to switch serially among multiple independent settings, wherein the combination of the settings of the first and second polarization modulators defines an independent polarization channel, and wherein an imaging detector produces a set of spatially registered images that are synchronized with the channels formed by the polarization modulators; and wherein a processor connected with a memory executes a classification algorithm stored in the memory that maps the set of images to one or more material orientation images by mapping the set of values for each detector pixel corresponding to the set of spatially registered images to a value of material orientation at each pixel coordinate using a machine-learning model, an electrodynamic model, or a combination thereof. The invention can thereby create material microstructural orientation images of diverse anisotropic materials, for instance polymer domains, fiber bundles or plys, and metallic crystalline grains. |
| FILED | Tuesday, January 21, 2020 |
| APPL NO | 16/748463 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/21 (20130101) G01N 2021/8477 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0068 (20130101) G02B 21/0092 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867937 | Rubin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Noah A. Rubin (Cambridge, Massachusetts); Federico Capasso (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides an optical component, which may be a metasurface grating, including (a) a substrate; and (b) an array of subwavelength-spaced phase-shifting elements, which are tessellated on the substrate to produce, when illuminated with a polarized incident light, a diffracted light beam with a distinct polarization state for each of a finite number of diffraction orders, wherein the finite number is 2 or more. |
| FILED | Wednesday, October 13, 2021 |
| APPL NO | 17/500913 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) Optical Elements, Systems, or Apparatus G02B 5/3025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11868095 | Saffman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Mark Saffman (Madison, Wisconsin); Shimon Kolkowitz (Madison, Wisconsin); Arjav Sharma (Madison, Wisconsin) |
| ABSTRACT | An atomic clock employs alkali metal atoms such as cesium normally used for microwave atomic clocks but with optical stimulation. While alkali metals provide light emissions having a spectral width being as much as 107 wider (and hence less precise) than alkali earth materials commonly targeted for optical atomic clocks, the present inventors have determined that this disadvantage is significantly reduced by improved signal-to-noise ratio in the obtained signal making practical an atomic clock with improved size, weight, and power consumption. |
| FILED | Tuesday, March 15, 2022 |
| APPL NO | 17/654888 |
| ART UNIT | 2849 — Electrical Circuits and Systems |
| CURRENT CPC | Time-interval Measuring G04F 5/145 (20130101) Original (OR) Class Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11868283 | Bertacco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Valeria Bertacco (Ann Arbor, Michigan); Abraham Addisie (Ann Arbor, Michigan) |
| ABSTRACT | The increased use of graph algorithms in diverse fields has highlighted their inefficiencies in current chip-multiprocessor (CMP) architectures, primarily due to their seemingly random-access patterns to off-chip memory. Here, a novel computer memory architecture is proposed that processes operations on vertex data in on-chip memory and off-chip memory. The hybrid computer memory architecture utilizes a vertex's degree as a proxy to determine whether to process related operations in on-memory or off-chip memory. The proposed computer memory architecture manages to provide up to 4.0× improvement in performance and 3.8× in energy benefits, compared to a baseline CMP, and up to a 2.0× performance boost over state-of-the-art specialized solutions. |
| FILED | Friday, July 17, 2020 |
| APPL NO | 16/932183 |
| ART UNIT | 2162 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0655 (20130101) G06F 13/1668 (20130101) Original (OR) Class G06F 13/4027 (20130101) G06F 13/4282 (20130101) G06F 16/9024 (20190101) G06F 16/9558 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11869176 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Wen Shi (Los Angeles, California); Eun Sang Koo (Los Angeles, California); Scott E. Fraser (Los Angeles, California); Francesco Cutrale (Los Angeles, California) |
| ABSTRACT | This invention relates to a hyperspectral imaging system for denoising and/or color unmixing multiple overlapping spectra in a low signal-to-noise regime with a fast analysis time. This system may carry out Hyper-Spectral Phasors (HySP) calculations to effectively analyze hyper-spectral time-lapse data. For example, this system may carry out Hyper-Spectral Phasors (HySP) calculations to effectively analyze five-dimensional (5D) hyper-spectral time-lapse data. Advantages of this imaging system may include: (a) fast computational speed, (b) the ease of phasor analysis, and (c) a denoising algorithm to obtain the minimally-acceptable signal-to-noise ratio (SNR). An unmixed color image of a target may be generated. These images may be used in diagnosis of a health condition, which may enhance a patient's clinical outcome and evolution of the patient's health. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 17/427890 |
| ART UNIT | 2425 — Cable and Television |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/441 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/2823 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/10 (20130101) Original (OR) Class G06T 2207/10024 (20130101) G06T 2207/20056 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11869222 | Mullen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert E. Mullen (Bloomington, Indiana); James A. Hammack (Huntsville, Alabama) |
| ABSTRACT | Provided are methods and apparatus for creating super-compressed map files. Using free and open-source software (FOSS), the tool create a super-compressed internally tiled Geo Tag Image File Format (TIFF) in a WGS84 datum (WGS84) similar in size to the original LizardTech's MrSID (SID) imagery from the National Geospatial-Intelligence Agency (NGA). Converting NGA data to WGS84 allows mapping systems like NASA Worldwind (WW) to eliminate the step of re-projecting on the fly from non-native projections, thus reducing processing time. The disclosed method includes removing all pure-black pixels by setting them to black+1, changing all near-black border pixels with values less than 15 to 0 (pure black), setting pure black values to “no-data,” compressing the image with a compression scheme, and translating the compressed image to JPEG and a YCbCr color space to achieve greater compression. |
| FILED | Thursday, March 10, 2022 |
| APPL NO | 17/691712 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/90 (20170101) G06T 9/20 (20130101) Original (OR) Class G06T 2207/10032 (20130101) G06T 2207/30181 (20130101) G06T 2207/30184 (20130101) Image or Video Recognition or Understanding G06V 20/13 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870005 | Efros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Alexander L. Efros (Annandale, Virginia); Michael Shur (Troy, New York) |
| ABSTRACT | An optoelectronic device comprising at least one quantum well (QW) and at least one quantum dot (QD) incorporated in the quantum well with the band gap of the quantum well being larger than the band gap of the quantum dot. The QDs and QD arrays are embedded in various QW, thus providing higher yields in optoelectronic devices, such as light emitting diodes, lasers, and photodetectors. This is achieved by a nearly complete suppression of the nonradiative Auger recombination and enhancement of the light extraction efficiency. |
| FILED | Tuesday, June 30, 2020 |
| APPL NO | 16/916690 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/06 (20130101) Original (OR) Class H01L 33/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870032 | Yersak et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Thomas A. Yersak (San Diego, California); Se-Hee Lee (Louisville, Colorado); Conrad Stoldt (Golden, Colorado) |
| ABSTRACT | An all-solid-state lithium battery, thermo-electromechanical activation of Li2S in sulfide based solid state electrolyte with transition metal sulfides, and electromechanical evolution of a bulk-type all-solid-state iron sulfur cathode, are disclosed. An example all-solid-state lithium battery includes a cathode having a transition metal sulfide mixed with elemental sulfur to increase electrical conductivity. In one example method of in-situ electromechanically synthesis of Pyrite (FeS2) from Sulfide (FeS) and elemental sulfur (S) precursors for operation of a solid-state lithium battery, FeS+S composite electrodes are cycled at moderately elevated temperatures. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/672555 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) H01M 4/382 (20130101) H01M 4/386 (20130101) H01M 4/5815 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870057 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Navitas Systems, LLC (Woodridge, Illinois) |
| ASSIGNEE(S) | Navitas Systems, LLC (Ann Arbor, Michigan) |
| INVENTOR(S) | Pu Zhang (Ann Arbor, Michigan); Michael Wixom (Ann Arbor, Michigan); Robert Sosik (Ann Arbor, Michigan) |
| ABSTRACT | Methods for preparing an electrode may include compressing an electrode dry mixture comprising an active material and an electrolyte material to form an electrode film. An electrolyte dry mixture or a stand-alone solid-state electrolyte film is compressed against a surface of the electrode film to form a laminate of an electrolyte layer and the electrode film. The electrolyte dry mixture may include the electrolyte material. Compressing the electrode dry mixture may include calendering the electrode dry mixture. Compressing the electrolyte dry mixture or stand-alone electrolyte film may be accomplished also by calendering. The electrolyte material may include a glass ceramic and, optionally, an air-stabilizing dopant. The glass ceramic may include Li3PS4. Thus, the electrodes may include a composite cathode and a solid-state electrolyte layer. The methods may be applicable for a solvent-free process to form electrodes and electrochemical cells and batteries including the electrodes. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/268811 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/043 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/382 (20130101) H01M 4/628 (20130101) H01M 4/1395 (20130101) Original (OR) Class H01M 10/052 (20130101) H01M 10/0562 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870084 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aspen Aerogels, Inc. (, None) |
| ASSIGNEE(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
| INVENTOR(S) | Owen Richard Evans (Chelmsford, Massachusetts); Nicholas Anthony Zafiropoulos (Wayland, Massachusetts); Shannon Olga White (Bolton, Massachusetts); Wenting Dong (Marlborough, Massachusetts); Wendell E. Rhine (Belmont, Massachusetts) |
| ABSTRACT | The present invention provides a fiber-reinforced aerogel material which can be used as insulation in thermal battery applications. The fiber-reinforced aerogel material is highly durable, flexible, and has a thermal performance that exceeds the insulation materials currently used in thermal battery applications. The fiber-reinforced aerogel insulation material can be as thin as 1 mm less, and can have a thickness variation as low as 2% or less. Also provided is a method for improving the performance of a thermal battery by incorporating a reinforced aerogel material into the thermal battery. Further provided is a casting method for producing thin fiber-reinforced aerogel materials. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/160369 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0091 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/36 (20130101) H01M 6/5072 (20130101) H01M 50/116 (20210101) H01M 50/117 (20210101) H01M 50/121 (20210101) H01M 50/122 (20210101) H01M 50/124 (20210101) H01M 50/131 (20210101) H01M 50/133 (20210101) H01M 50/138 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870148 | Crouch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | David D. Crouch (Farragut, Tennessee); Hooman Kazemi (Thousand Oaks, California); Alexander Borisovich Brailovsky (Irvine, California) |
| ABSTRACT | A planar conductive millimeter-wave lens includes: a planar conductive plate with a first surface and a second surface, wherein the first surface is parallel to the second surface; a plurality of openings from the first surface through the planar conductive plate to the second surface, where an axis of each opening is perpendicular to the first surface and the second surface. A size of each opening is a function of a position of said each opening on the planar conductive plate such that an insertion phase collectively imposed by the openings on an incident wave causes the incident wave to pass through the first surface and the planar conductive plate, exit from the second surface and to focus at a predetermined distance from the second surface. |
| FILED | Thursday, November 11, 2021 |
| APPL NO | 17/524644 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 19/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870216 | Stern et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Brian Stern (New York, New York); Xingchen Ji (New York, New York); Michal Lipson (New York, New York) |
| ABSTRACT | An on-chip laser includes a gain portion, a mirror in communication with the gain portion, a waveguide in communication with the gain portion, and a resonator optically coupled to the waveguide at an optical coupling. The resonator has a circular shape. The waveguide and the resonator are separate from the gain portion. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/651673 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/141 (20130101) Original (OR) Class H01S 5/142 (20130101) H01S 5/0234 (20210101) H01S 5/1028 (20130101) H01S 5/02325 (20210101) H01S 5/3013 (20130101) H01S 5/06837 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870372 | West et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | James West (Baltimore, Maryland); Ugur Erturun (Baltimore, Maryland); Sung Hoon Kang (Lutherville-Timonium, Maryland); Adebayo Eisape (Baltimore, Maryland) |
| ABSTRACT | Disclosed are device implementations for a hybrid energy harvesting device and methods for harvesting mechanical energy from the ambient. The various device implementations utilize a combination of electrostatic energy conversion and piezoelectric energy conversion elements. The method simultaneously converts mechanical energy into electrical charge by electrostatic and piezoelectric energy harvesting. The devices include a piezoelectric harvester including a pair of electrodes and piezoelectric nanocomposite polymer, an electrostatic harvester including an electret film and a pair of electrostatic electrodes. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 17/059735 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) H02N 2/181 (20130101) H02N 2/186 (20130101) Original (OR) Class Electric solid-state devices not otherwise provided for H10N 30/30 (20230201) H10N 30/852 (20230201) H10N 30/872 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870459 | Solomon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts); National University of Ireland, Maynooth (Maynooth, Ireland) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); National University of Ireland Maynooth (Maynooth, Ireland); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Amit Solomon (Cambridge, Massachusetts); Muriel Medard (Belmont, Massachusetts); Kenneth R. Duffy (Dublin, Ireland); Rabia Tugce Yazicigil Kirby (Cambridge, Massachusetts); Vaibhav Bansal (Boston, Massachusetts); Wei An (Newton, Massachusetts) |
| ABSTRACT | Described is a decoder suitable for use with any communication or storage system. The described decoder has a modular decoder hardware architecture capable of implementing a noise guessing process and due to its dependency only on noise, the decoder design is independent of any encoder, thus making it a universal decoder. Hence, the decoder architecture described herein is agnostic to any coding scheme. |
| FILED | Thursday, April 08, 2021 |
| APPL NO | 17/225818 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/1105 (20130101) Original (OR) Class H03M 13/1148 (20130101) H03M 13/2778 (20130101) H03M 13/6575 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11871131 | Gulbransen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | David J. Gulbransen (Fairview, Texas); Jae H. Kyung (Redondo Beach, California); Chaffra A. Affouda (Santa Barbara, California) |
| ABSTRACT | An apparatus includes a sensor having an array of detectors. The sensor is configured to assign multiple detectors to a detector group corresponding to a block pixel. The sensor is also configured, for each frame of a set of frames, to apply a specified one of a set of mask patterns in order to select outputs of the detectors in the detector group and aggregate the selected outputs of the detectors in the detector group to determine pixel information for the block pixel. The apparatus also includes at least one processor configured to generate the frames using the pixel information for the block pixel, and upscale the portion of the at least one of the frames using the set of mask patterns to identify native pixels within the block pixel. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396436 |
| ART UNIT | 2698 — Selective Visual Display Systems |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/40 (20130101) Pictorial Communication, e.g Television H04N 25/75 (20230101) H04N 25/702 (20230101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11871180 | Byrne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Matthew S. Byrne (Austin, Texas); Hussein Esfahlani (Lausanne, Switzerland); Andrea Alu (Austin, Texas) |
| ABSTRACT | Supercoupling waveguides are provided in which acoustic impedance at an acoustic input port matches the acoustic impedance at an acoustic output port, where the acoustic path extending from the acoustic input port to the acoustic output port has a variable length. The supercoupling waveguides may be used in methods of sensing and measuring, and may be incorporated into sensors. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/702264 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 15/00 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/18 (20130101) G10K 11/025 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/345 (20130101) H04R 1/2857 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11864989 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Thomas S. Wilson (Castro Valley, California); Duncan J. Maitland (College Station, Texas); Ward Small, IV (Livermore, California); Patrick R. Buckley (Alameda, California); William J. Benett (Livermore, California); Jonathan Hartman (Sacramento, California); David Saloner (San Rafael, California) |
| ABSTRACT | A system comprising first, second, and third shape memory polymers (SMPs); wherein (a) the first SMP is a biodegradable open cell foam that includes a first channel; (b) the second SMP includes a second channel and is included in the first channel; (c) the foam is in a first state and is configured to expand to a second state, radially outward from the second foam, in response to thermal stimulus; (d) the third SMP is between the first and second SMPs and includes a stent having a first strut that includes the third SMP and a second strut that includes the third SMP; and (e) each of the first, second, and third SMPs is coupled to a wire. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/070053 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1214 (20130101) A61B 17/12022 (20130101) A61B 17/12031 (20130101) A61B 17/12113 (20130101) A61B 17/12118 (20130101) A61B 17/12181 (20130101) A61B 2017/00867 (20130101) A61B 2017/00871 (20130101) A61B 2017/1205 (20130101) A61B 2017/12054 (20130101) A61B 2017/12072 (20130101) A61B 2017/12077 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/06 (20130101) Original (OR) Class A61F 2/82 (20130101) A61F 2/95 (20130101) A61F 2002/823 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865476 | Restivo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Battelle Savannah River Alliance, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Michael L. Restivo (Aiken, South Carolina); Michael R. Poirier (Evans, Georgia); Fernando F. Fondeur (North Augusta, South Carolina); Samuel D. Fink (Aiken, South Carolina) |
| ABSTRACT | Centrifugal contactors that can be used for mixing or separating materials are described. The contactors include a sensing system including a communications fiber within the shaft of the contactors and access ports providing access from the communications fiber to the mixing/separating zone of the contactor. The sensing system can be utilized during operation of the contactor and can provide for detailed and accurate on-line characterization of a protocol, as well as process control and system modification as necessary during operation. |
| FILED | Tuesday, March 07, 2023 |
| APPL NO | 18/179602 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 11/048 (20130101) Original (OR) Class B01D 11/0434 (20130101) B01D 11/0461 (20130101) B01D 11/0484 (20130101) Centrifuges B04B 1/02 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865556 | Hossain et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Mohammad Arif Hossain (Lake Jackson, Texas); Jeffrey P. Bons (Dublin, Ohio); James W. Gregory (Columbus, Ohio); Ali Ameri (Solon, Ohio) |
| ABSTRACT | Various implementations include, an out-of-plane feedback-type fluidic oscillator. including a first portion, a second portion, a middle portion coupled between the first portion and the middle portion, and an axis of rotation. The middle portion includes a first side, a second side opposite and spaced apart from the first side, and a middle plane, an interaction chamber, a fluid supply inlet, an outlet nozzle, a first feedback a channel, and a second feedback channel. The first side is coupled to the first portion, and the second side is coupled to the second portion. The first side, the second side, and the middle plane extend circumferentially around the axis of rotation. The middle plane is disposed equally distanced from the first side and the second side. The fluid stream oscillates as it flows through the interaction chamber such that the fluid stream oscillates as the fluid stream exits the outlet nozzle. |
| FILED | Thursday, May 28, 2020 |
| APPL NO | 17/614135 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/08 (20130101) Original (OR) Class Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865636 | Ye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jianchao Ye (Tracy, California); John Roehling (Livermore, California); Jae Hyuck Yoo (Dublin, California) |
| ABSTRACT | The present disclosure relates to a system for laser processing of a ceramic electrolyte material. The system may include a controller, a laser responsive to the controller for generating a beam, and a beam forming subsystem. The beam forming subsystem controls a parameter of the beam generated by the laser. The beam forming subsystem further controls the beam to provide a laser fluence sufficient to produce densification of the ceramic electrolyte material. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 16/783910 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0622 (20151001) Original (OR) Class B23K 2103/52 (20180801) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/124 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/1024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866061 | Poull et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| ASSIGNEE(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| INVENTOR(S) | Claude P. Poull (Houdemont, Belgium); Karim Aggoune (Auburn Hills, Michigan) |
| ABSTRACT | A method for providing a visual driving speed recommendation to an operator of a vehicle includes determining a current speed; determining a corresponding energy efficient speed; determining a higher corresponding less energy efficient speed; determining a first transition range between the corresponding energy efficient speed and the higher corresponding less energy efficient speed; and displaying, on a display, a display zone, the display zone comprising: a first indicator corresponding to the current speed; a first pattern corresponding to the corresponding energy efficient speed; a second pattern different from the first pattern and corresponding to the higher corresponding less energy efficient speed; and a first pattern range therebetween corresponding to the first transition range. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/464236 |
| ART UNIT | 2684 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 35/00 (20130101) B60K 2370/167 (20190501) B60K 2370/188 (20190501) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/143 (20130101) B60W 30/18072 (20130101) B60W 40/105 (20130101) B60W 50/14 (20130101) Original (OR) Class B60W 2050/146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866322 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jin Wang (Hinsdale, Illinois); Donald A. Walko (Woodridge, Illinois); Pice Chen (Lemont, Illinois); Il Woong Jung (Lemont, Illinois); Daniel Lopez (Lemont, Illinois) |
| ABSTRACT | A microelectromechanical device for diffracting optical beams comprises a diffractive element suspended over a channel. The diffractive element is configured to receive an optical beam and diffract and/or transmit the optical beam based on an orientation of the diffractive element. At least one torsional actuator is operatively connected to the diffractive element. The at least one torsional actuator is configured to selectively adjust the orientation of the diffractive element. The diffractive element has a diffractive element resonant frequency that is nearly the same as a resonant frequency of the optical beam. |
| FILED | Tuesday, March 09, 2021 |
| APPL NO | 17/196710 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0083 (20130101) Original (OR) Class B81B 2201/047 (20130101) Optical Elements, Systems, or Apparatus G02B 27/4233 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866555 | Hopkinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | Energy, United States Department of (Washington, District of Columbia) |
| INVENTOR(S) | David Hopkinson (Morgantown, West Virginia); Victor Armanda Kusuma (Pittsburgh, Pennsylvania); Surendar R. Venna (Missouri City, Texas); Joshua S. McNally (Idaho Falls, Idaho); Christopher J. Orme (Firth, Idaho); Frederick F. Stewart (Idaho Falls, Idaho) |
| ABSTRACT | The disclosed invention relates to a composition comprising a crosslinked blend of polyphosphazene polymers. The composition comprises a first polyphosphazene and a second polyphosphazene, where the first polyphosphazene and the second polyphosphazene being bound by a thiol bearing crosslinking agent. Such compositions are useful as a membrane material for the separation of gasses in a gaseous mixture. |
| FILED | Monday, August 19, 2019 |
| APPL NO | 16/543928 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Separation B01D 53/1475 (20130101) B01D 71/58 (20130101) B01D 2256/24 (20130101) B01D 2257/504 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/025 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/37 (20130101) C08K 5/548 (20130101) Compositions of Macromolecular Compounds C08L 71/08 (20130101) C08L 79/08 (20130101) C08L 81/06 (20130101) C08L 85/02 (20130101) C08L 2312/00 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 47/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866594 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Stephanie Schulze (Lenexa, Kansas) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Stephanie Schulze (Lenexa, Kansas) |
| INVENTOR(S) | Amanda Wu (Dublin, California); Taylor Maxwell Bryson (Newbury Park, California); Eric Duoss (Dublin, California); Thomas R. Metz (Tracy, California); Ward Small (Livermore, California); Thomas S. Wilson (San Leandro, California); Stephanie Schulze (Lenexa, Kansas); Emily Cheng (Ballwin, Missouri) |
| ABSTRACT | In accordance with one aspect of the presently disclosed inventive concepts, a product includes a porous three-dimensional (3D) printed polymer structure having elastomeric shape memory, where the structure includes a material comprising a plurality of gas-filled microballoons. The 3D printed polymer structure has hierarchical porosity. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/610215 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/165 (20130101) B29K 2509/02 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) B33Y 80/00 (20141201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/037 (20130101) C09D 11/102 (20130101) Original (OR) Class Electric Digital Data Processing G06F 9/321 (20130101) G06F 9/546 (20130101) G06F 9/4812 (20130101) G06F 9/4881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866775 | Gang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Oleg Gang (Setauket, New York); Suchetan Pal (New York, New York) |
| ABSTRACT | The present method of detection involves increasing an amount of analyte molecules by an isothermal molecular amplification approach. In the present approach a starting molecule of interest may be amplified through a reaction it induces with specifically engineered and functionalized particles, namely protected particles A and storage particles B. This reaction may result in a set of output DNA molecules that is larger in number than the input DNA molecules. Thus the reaction between nanoparticles for amplification of a certain DNA sequence (input DNA molecules) may occur when there is a match with a targeted molecule (stored molecules on storage particles B) and if the DNA sequence of the input DNA molecules does not match (partially or completely) the targeted molecule the reaction may not occur. Without a certain molecular input of the input DNA molecule the reaction may not occur. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/065255 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6844 (20130101) C12Q 1/6853 (20130101) C12Q 1/6862 (20130101) Original (OR) Class C12Q 2527/107 (20130101) C12Q 2527/107 (20130101) C12Q 2537/125 (20130101) C12Q 2537/125 (20130101) C12Q 2537/155 (20130101) C12Q 2537/155 (20130101) C12Q 2545/101 (20130101) C12Q 2563/149 (20130101) C12Q 2563/155 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866809 | Muralidharan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Govindarajan Muralidharan (Knoxville, Tennessee); Michael P. Brady (Oak Ridge, Tennessee); Yukinori Yamamoto (Knoxville, Tennessee) |
| ABSTRACT | An austenitic Ni-base alloy, consisting essentially of, in weight percent: 2.5 to 4.75 Al; 21 to 26 Cr; 20 to 40 Fe; 0.75 to 2.5 total of at least one element elected from the group consisting of Nb and Ta; 0 to 0.25 Ti; 0.09 to 1.5 Si; 0 to 0.5 V; 0 to 2 Mn; 0 to 3 Cu; 0 to 2 of at least one element selected from the group consisting of Mo and W; 0 to 1 of at least one element selected from the group consisting of Zr and Hf; 0 to 0.15 Y; 0.3 to 0.55 C; 0.005 to 0.1 B; 0 to 0.05 P; less than 0.06 N and balance Ni (30 to 46 Ni), wherein the weight percent Ni is greater than the weight percent Fe, and wherein the ratio Ni/(Fe+2*C) is between 1.02 and 1.067. |
| FILED | Friday, January 29, 2021 |
| APPL NO | 17/162917 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 9/00 (20130101) B32B 2315/02 (20130101) Alloys C22C 19/055 (20130101) C22C 30/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866847 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Fang Liu (New York, New York); Xiaoyang Zhu (New York, New York); James Hone (New York, New York); Sang Hoon Chae (New York, New York) |
| ABSTRACT | Systems and methods for generating one or more single crystal monolayers from two-dimensional van der Waals crystals are disclosed herein. Example methods include providing a bulk material including a plurality of van der Waals crystal layers, and exfoliating one or more single crystal monolayers of van der Waals crystal from the bulk material by applying a flexible and flat metal tape to a surface of the bulk material. In certain embodiments, the one or more single crystal monolayers can be assembled into an artificial lattice. The present disclosure also provides techniques for manufacturing flexible and flat metal tape for generating one or more single crystal monolayers from two-dimensional van der Waals crystals. The present disclosure also provides compositions for creating a macroscopic artificial lattice. In certain embodiments, the composition can include two or more macroscopic single crystal monolayers adapted from a bulk van der Waals crystal, where the single crystal monolayers are configured for assembly into an artificial lattice based on one or more properties. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/105105 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/02 (20130101) B32B 18/00 (20130101) B32B 37/18 (20130101) B32B 37/025 (20130101) B32B 43/006 (20130101) B32B 2315/02 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 39/06 (20130101) C01G 41/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/24 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/16 (20130101) C23C 14/30 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/46 (20130101) C30B 29/68 (20130101) C30B 33/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867059 | Staack et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | David Staack (College Station, Texas); Li-Jung Tai (Bryan, Texas); Dion S. Antao (College Station, Texas); Xin Tang (College Station, Texas) |
| ABSTRACT | Systems and methods for drilling a borehole are disclosed. In an embodiment, the system includes a drill bit and a plasma inducing apparatus coupled to the drill bit. The plasma inducing apparatus is configured to generate plasma. |
| FILED | Wednesday, October 30, 2019 |
| APPL NO | 17/288648 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 4/02 (20130101) E21B 7/15 (20130101) Original (OR) Class E21B 10/42 (20130101) E21B 41/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867638 | Forien et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jean-Baptiste Forien (Livermore, California); Nicholas P. Calta (San Jose, California); Gabriel Mark Guss (Manteca, California); Manyalibo Joseph Matthews (Livermore, California) |
| ABSTRACT | A system and method is disclosed for detecting anomalies in an additively manufactured part. An energy source generates a signal forming an optical beam for creating a melt pool in a layer of feedstock material being selectively fused to make a part in an additive manufacturing operation. A sensor is configured to receive a signal reflected from the melt pool. The reflected signal forms a thermal signal indicative of a temperature of the feedstock material at a known location on a layer of the feedstock material while the feedstock material is being fused at the known location. A controller receives and analyzes data relating to the received signal to determine if an anomaly exists at the known location. |
| FILED | Wednesday, October 28, 2020 |
| APPL NO | 17/082855 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/80 (20210101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/95 (20130101) G01N 21/8806 (20130101) Original (OR) Class G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867677 | Christensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Daniel A. Christensen (Kansas City, Missouri); Ratthatrust Leryoskajai (Kansas City, Missouri); Nathan S. L. Volkmann (Lee's Summit, Missouri) |
| ABSTRACT | A sensor discriminator for detecting a gaseous substance includes a power source, a discrimination module, a sensor simulator that simulates a metal organic framework under at least one simulation condition, a simulation circuitry electrically coupling the sensor simulator to the power source and the discrimination module, and a discriminator circuitry that electrically couples the power source and the discrimination module to a gas capture probe. The discrimination module compares a discrimination pulse and a simulation pulse from the power source after the discrimination pulse passes through a metal organic framework of the gas capture sensor and the simulation pulse passes through a simulation component of the sensor simulator. The discrimination module causes a discriminator output that includes the comparison of the discrimination pulse to the simulation pulse. An electrical property of the discrimination pulse depends on an electrical parameter of the metal organic framework that is augmented by the gaseous substance. |
| FILED | Friday, November 18, 2022 |
| APPL NO | 17/990144 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0034 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867769 | Tong |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Shijie Tong (San Diego, California) |
| ABSTRACT | A system, a method, and a computer program product for providing heterogeneous unifying battery storage. A state-of-health value of a battery is determined. The state-of-health value of the battery is less than an original capacity value of the battery. The battery is connected to an electrical power source for re-conditioning. A target state-of-health value for the battery and a number of cycles required to achieve the target state-of-health value of the battery are determined. Each cycle in the number of cycles includes at least one of: a charging the battery and a discharging the battery. The battery is re-conditioned by cycling the battery using the determined number of cycles. Cycling includes drawing electrical power from the electrical power source. |
| FILED | Thursday, February 20, 2020 |
| APPL NO | 17/432084 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/392 (20190101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0069 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867866 | Podpaly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Yuri Podpaly (Hayward, California); James M. Hall (Livermore, California); Alexander Peter Povilus (Livermore, California); Andrea Schmidt (Livermore, California); Dustin Yang (Atlanta, Georgia) |
| ABSTRACT | A system and method is disclosed for detecting fissionable materials. In one embodiment the system may incorporate a neutron pulse generator configured to generate multiple short pulses of neutrons, or a single pulse of sufficient intensity, in a vicinity of an object of interest. The source pulse of neutrons includes neutrons which each have a full width half maximum time duration of less than about 100 ns and a peak energy level no greater than about 20 MeV. A fast response detector is used which is able to detect single neutron events indicative of fission neutrons having been produced by the source pulse of neutrons interacting with fissionable material associated with the object of interest, and which arrive at the fast response detector within a predetermined time window immediately before arrival of the source neutron pulses. |
| FILED | Tuesday, August 06, 2019 |
| APPL NO | 16/532707 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/222 (20130101) Measurement of Nuclear or X-radiation G01T 3/06 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0016 (20130101) G01V 5/0091 (20130101) Original (OR) Class Fusion Reactors G21B 1/03 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 4/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11868025 | Muir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermora, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Ryan D. Muir (Livermore, California); Vincent J. Hernandez (Brisbane, California); Brandon W. Buckley (Walnut Creek, California); Daniel E. Mittelberger (Livermore, California); John E. Heebner (San Ramon, California) |
| ABSTRACT | Apparatuses comprising cascaded or series configurations of Mach-Zehnder electrooptic modulators, where the nonlinearities of the cascaded and series configurations of Mach-Zehnder electrooptic modulators increase signal bandwidth and boost signal fidelity in electronic digital to analog converters. The Mach-Zehnder electrooptic modulators are combined with photodiode detectors that are used to convert signals from the optical domain to the electrical domain. |
| FILED | Wednesday, October 21, 2020 |
| APPL NO | 17/075953 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) G02F 1/2255 (20130101) G02F 1/2257 (20130101) G02F 7/00 (20130101) Original (OR) Class Transmission H04B 10/556 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11868809 | Hassaan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Muhammad Amber Hassaan (Austin, Texas); Anirudh Mohan Kaushik (Austin, Texas); Sooraj Puthoor (Austin, Texas); Gokul Subramanian Ravi (Austin, Texas); Bradford Beckmann (Bellevue, Washington); Ashwin Aji (Santa Clara, California) |
| ABSTRACT | A processor includes a task scheduling unit and a compute unit coupled to the task scheduling unit. The task scheduling unit performs a task dependency assessment of a task dependency graph and task data requirements that correspond to each task of the plurality of tasks. Based on the task dependency assessment, the task scheduling unit schedules a first task of the plurality of tasks and a second proxy object of a plurality of proxy objects specified by the task data requirements such that a memory transfer of the second proxy object of the plurality of proxy objects occurs while the first task is being executed. |
| FILED | Wednesday, January 11, 2023 |
| APPL NO | 18/095704 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/52 (20130101) G06F 9/4881 (20130101) Original (OR) Class G06F 16/9024 (20190101) G06F 2209/486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870044 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Kandler Alan Smith (Golden, Colorado); Shriram Santhanagopalan (Broomfield, Colorado); Nathaniel Alexander Sunderlin (Golden, Colorado); Andrew Michael Colclasure (Morrison, Colorado); Chunmei Ban (Golden, Colorado); Xuemin Li (Lakewood, Colorado); Judy C. Netter (Westminster, Colorado); Donal Patrick Finegan (Golden, Colorado); Kaitlin Elizabeth Fink (Lakewood, Colorado); Jaclyn Elizabeth Coyle (Westminster, Colorado) |
| ABSTRACT | Among other things, the present disclosure relates to re-purposing used lithium-ion batteries. The present disclosure includes treating an electrode using a solvent prior to electrochemically relithiating the electrode. In some embodiments, the relithiation may be done using a roll-to-roll device, wherein the electrode may be secured on a first pin and a second pin, then it may be unwound and submerged in an electrolyte solution. Lithium ions may be inserted into the electrode using a voltage. The layer of lithium may provide lithium ions to the electrode. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 17/514004 |
| ART UNIT | 1759 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/049 (20130101) H01M 4/139 (20130101) H01M 10/54 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0587 (20130101) H01M 2004/8689 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870069 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Apple Inc. (Cupertino, California) |
| ASSIGNEE(S) | Apple Inc. (Cupertino, California) |
| INVENTOR(S) | Huiming Wu (San Jose, California); Hongli Dai (Los Altos, California); Dapeng Wang (Cupertino, California); Christopher S. Johnson (Naperville, Illinois); John David Carter (Bolingbrook, Illinois); Yanjie Cui (Arlington Heights, California); Arturo Gutierrez (Naperville, Illinois); Hakim H Iddir (Hoffman Estates, Illinois); Arthur Jeremy Kropf (Westmont, Illinois); Yan Li (Westmont, Illinois); Victor A. Maroni (Naperville, Illinois); Anh D. Vu (Naperville, Illinois); Xiaoping Wang (Naperville, Illinois); Zhenzhen Yang (Westmont, Illinois) |
| ABSTRACT | Compounds, powders, and cathode active materials that can be used in lithium ion batteries are described herein. Methods of making such compounds, powders, and cathode active materials are described. |
| FILED | Thursday, November 01, 2018 |
| APPL NO | 16/178304 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/366 (20130101) H01M 4/0471 (20130101) H01M 4/485 (20130101) H01M 4/502 (20130101) H01M 4/505 (20130101) H01M 4/523 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 4/582 (20130101) H01M 4/661 (20130101) H01M 4/5825 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101) H01M 2004/028 (20130101) H01M 2220/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870263 | Griffith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Channing Street Copper Company (Berkeley, California) |
| ASSIGNEE(S) | CHANNING STREET COPPER COMPANY (Berkeley, California) |
| INVENTOR(S) | Saul Thomas Griffith (San Francisco, California); Samuel Eli Calisch (Berkeley, California); Joshua Land (San Francisco, California); Tucker Gilman (Berkeley, California) |
| ABSTRACT | A powered building system that includes an electric power distribution system configured to distribute electrical power to a plurality of receptacles; one or more load sources; and one or more battery systems associated with: a respective receptacle of the plurality of receptacles and a respective load source of the one or more load sources. |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/692714 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/4207 (20130101) H01M 50/204 (20210101) H01M 50/251 (20210101) H01M 2220/10 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/32 (20130101) Original (OR) Class H02J 3/381 (20130101) H02J 7/0013 (20130101) H02J 7/00032 (20200101) H02J 7/0063 (20130101) H02J 7/342 (20200101) H02J 2300/24 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870311 | Brown |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ian Patrick Brown (Evanston, Illinois) |
| ASSIGNEE(S) | ILLINOIS INSTITUTE OF TECHNOLOGY (Chicago, Illinois) |
| INVENTOR(S) | Ian Patrick Brown (Evanston, Illinois) |
| ABSTRACT | A conductive coil for an electric application having a cooling channel for a coolant liquid or gas. The coil includes a wire winding of a plurality of wire turns. The wire winding is compressed about a cooling channel which is disposed between adjacent turn segments of the plurality of wire turns. The wire winding is formed and pressed against a shaping element to form the coolant channel within the compressed winding. |
| FILED | Monday, January 25, 2021 |
| APPL NO | 17/157396 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 1/20 (20130101) H02K 3/24 (20130101) Original (OR) Class H02K 3/28 (20130101) H02K 15/0093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870358 | Rastogi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DEERE and COMPANY (Moline, Illinois) |
| ASSIGNEE(S) | Deere and Company (Moline, Illinois) |
| INVENTOR(S) | Sagar K Rastogi (Raleigh, North Carolina); Brij N. Singh (West Fargo, North Dakota) |
| ABSTRACT | A system and method of fault detection based on a detailed waveform analysis is presented for transient and steady-state fault operation of 3-Φ DAB converter. Main symptoms of the converter during normal and fault conditions have been identified and a unique pattern in DC bias of phase currents under fault mode is noted. The logic-based fault diagnosis scheme is used to detect the fault and identify the faulty transistor. |
| FILED | Sunday, August 08, 2021 |
| APPL NO | 17/396739 |
| ART UNIT | 2839 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/325 (20210501) H02M 3/33584 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870366 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); UC Berkeley (Berkeley, California) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Minjie Chen (Princeton, New Jersey); Robert Pilawa-Podgurski (Berkeley, California) |
| ABSTRACT | According to various embodiments, a power conversion circuit is disclosed. The power conversion circuit includes at least one DC bus. The power conversion circuit further includes a plurality of DC-AC conversion units coupled to the DC bus and configured to convert a DC voltage into an AC voltage. The power conversion circuit also includes a multi-winding transformer comprising a magnetic core and a plurality of windings, where each DC-AC conversion unit is coupled to a corresponding winding of the multi-winding transformer. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 17/432793 |
| ART UNIT | 2896 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0013 (20130101) H02J 7/0014 (20130101) H02J 7/0016 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/0074 (20210501) H02M 1/0077 (20210501) H02M 1/0083 (20210501) H02M 7/493 (20130101) H02M 7/5387 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870439 | Zan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Xin Zan (Ann Arbor, Michigan); Al-Thaddeus Avestruz (Ann Arbor, Michigan) |
| ABSTRACT | A pulse shaping device includes an inductor that is selectively output-coupled to a first port of a capacitor. The inductor is charged to a selected current throughput and then coupled to the first port to generate a first characteristic within the current flowing at a second port of the capacitor. The capacitor is charged until reaching a clamping voltage at the first port. A voltage clamp of the shaping device clamps the first port of the capacitor at the clamping voltage to generate a second characteristic within the current flowing at a second port of the capacitor. |
| FILED | Thursday, December 08, 2022 |
| APPL NO | 18/077759 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 3/01 (20130101) Original (OR) Class H03K 5/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11864872 | Khine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Michelle Khine (Irvine, California); Nicole Eckmann (Folsom, California); Kimberly Veliz (Paramount, California); Jonathan Pegan (Irvine, California); Joshua Kim (Irvine, California); Sun-Jun Park (Irvine, California) |
| ABSTRACT | A method of estimating a continuous blood pressure waveform or a continuous blood pressure in a subject including: measuring an arterial blood pressure waveform or an arterial blood pressure with a sensor supported by a supporting structure comprising a polymeric substrate and connected to a processor and a transmitter, wherein the supporting structure is configured to press the sensor against a skin surface of a subject, wherein the sensor is configured to detect a biological metric of the subject, and wherein the processor is configured to quantify one or more signal(s) corresponding to the biological metric and the transmitter is configured to transmit the one or more signals to an external user system, and transforming the arterial blood pressure waveform or the arterial blood pressure to the continuous blood pressure waveform or the continuous blood pressure using a transfer function. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/156235 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/021 (20130101) A61B 5/024 (20130101) A61B 5/0816 (20130101) A61B 5/02055 (20130101) Original (OR) Class A61B 5/6824 (20130101) A61B 5/14542 (20130101) A61B 2562/12 (20130101) A61B 2562/0247 (20130101) A61B 2562/0261 (20130101) A61B 2562/0285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865101 | Lopez-Mejias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vilmali Lopez-Mejias (San Juan, Puerto Rico); Jeaninna P. Flores Bello (San Juan, Puerto Rico); Israel Rodriguez Rodriguez (San Juan, Puerto Rico); Joyce Marie Serrano Valcarcel (San Juan, Puerto Rico) |
| ASSIGNEE(S) | University of Puerto Rico (San Juan, Puerto Rico) |
| INVENTOR(S) | Vilmali Lopez-Mejias (San Juan, Puerto Rico); Jeaninna P. Flores Bello (San Juan, Puerto Rico); Israel Rodriguez Rodriguez (San Juan, Puerto Rico); Joyce Marie Serrano Valcarcel (San Juan, Puerto Rico) |
| ABSTRACT | A series of pharmaceutical metal complexes (pMCs) were produced and characterized using the mast cell stabilizer, cromolyn, and bioactive metal ions (Zn+2, Mg+2, and Ca+2). Three novel pMCs, Cromolyn-Zn, Cromolyn-Mg, and Cromolyn-Ca were formed through reactions under controlled temperature and pH conditions. TGA demonstrated that these metal complexes showed an enhanced thermal stability due to the strong coordination with the ligand, cromolyn. PXRD data indicates a high degree of crystallinity as well as a unique packing arrangement for each pMCs. SEM analysis showed materials with well-defined morphologies while EDS presented elemental evidence for the unique composition of each pMCs. The crystal structure for these materials was elucidated through SCXRD, and a variety of binding modes and packing motifs were found within each respective metal complex. Only 2D structures were achieved under the conditions studied. Dissolution studies show high stability and slow degradation for the metal complexes, while a higher dissolution was observed for the drug compound in PBS. Neither CS nor the pMCs dissolved significantly in FaSSGF at 37° C. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/307208 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865508 | Woodbury et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Neal Woodbury (Temple, Arizona); Zhang-Gong Zhao (Tucson, Arizona) |
| ABSTRACT | Described herein are in situ synthesized arrays and methods of making the them, wherein array signal sensitivity and robustness is enhanced by carrying out conditioning steps and/or generating linkers during synthesis. An array comprises a surface with a collection of features, wherein the features comprise molecules or polymers attached to the surface. In certain embodiments of the invention, carrying out conditioning steps during array synthesis can yield arrays with improved signal. In other embodiments, linkers are synthesized on the array surface prior to synthesis of functional molecules, wherein increasing linker length can correspond to an improvement in the signal generated by the array. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/008425 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) Original (OR) Class B01J 2219/00432 (20130101) B01J 2219/00596 (20130101) B01J 2219/00626 (20130101) B01J 2219/00659 (20130101) B01J 2219/00675 (20130101) B01J 2219/00725 (20130101) Peptides C07K 1/047 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/18 (20130101) C40B 80/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865594 | Quigley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut); Nicole Neff (North Potomac, Maryland); Jack Rowbottom (Swansea, Massachusetts) |
| ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system comprising a plurality of wells are provided herein. In some embodiments, the method comprises obtaining a concentration of a greenhouse gas measured a distance above a surface of a region comprising the plurality of wells; determining whether the measure of the concentration of the greenhouse gas is greater than a first threshold; and in response to determining that the measure of the concentration of the greenhouse gas is greater than the first threshold, increasing a flow rate of landfill gas being extracted from at least one well of the plurality of wells. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/540833 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class B09B 2101/25 (20220101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/30 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866339 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Michel W Barsoum (Moorestown, New Jersey); Di Zhao (Beijing, China PRC); Varun Natu (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure describes a crumpled form of Mxene materials, and methods of making and using these novel compositions. |
| FILED | Thursday, December 08, 2022 |
| APPL NO | 18/063093 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Flotation; Differential Sedimentation B03D 3/06 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/921 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/20 (20130101) C01P 2004/45 (20130101) C01P 2006/16 (20130101) C01P 2006/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866386 | Koide et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Kazunori Koide (Pittsburgh, Pennsylvania); James Proviano Burrows (West Homestead, Pennsylvania) |
| ABSTRACT | A method of reducing an aromatic ring or a cyclic, allylic ether in a compound includes preparing a reaction mixture including a compound including an aromatic moiety or a cyclic, allylic ether moiety, an alkali metal, and either ethylenediamine, diethylenetriamine, triethylenetetramine, or a combination thereof, in an ether solvent; and reacting the reaction mixture at from −20° C. to 30° C. for a time sufficient to reduce a double bond in the aromatic moiety to a single bond or to reduce the cyclic, allylic ether moiety. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/477900 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 31/00 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 41/20 (20130101) C07C 41/20 (20130101) C07C 43/188 (20130101) C07C 51/36 (20130101) C07C 51/36 (20130101) C07C 51/36 (20130101) C07C 51/347 (20130101) C07C 61/22 (20130101) C07C 61/28 (20130101) C07C 61/39 (20130101) C07C 67/30 (20130101) C07C 2523/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866629 | Bawendi et al. |
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| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Moungi Bawendi (Cambridge, Massachusetts); Daniel Franke (Cambridge, Massachusetts); Matthias Ginterseder (Cambridge, Massachusetts) |
| ABSTRACT | A semiconductor nanocrystal can be made by an in situ redox reaction between an M donor and an E donor. |
| FILED | Tuesday, January 12, 2021 |
| APPL NO | 17/147057 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 17/20 (20130101) C01B 19/04 (20130101) C01B 21/072 (20130101) C01B 21/0632 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 28/00 (20130101) C01G 30/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/0883 (20130101) C09K 11/883 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/0665 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866671 | Kraus et al. |
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| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | George A. Kraus (Ames, Iowa); Kyle Podolak (Ames, Iowa); Derek Lee White (Lakewood, Colorado); Sriram Sundararajan (Ames, Iowa) |
| ABSTRACT | The present invention is toward a base oil or lubricant additives, methods of using the same, lubricant compositions including the same, and methods of forming the lubricant compositions. A base oil or lubricant additive has Structure I or Structure II as described herein. |
| FILED | Wednesday, November 23, 2022 |
| APPL NO | 18/058635 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition C10M 129/70 (20130101) Original (OR) Class C10M 169/04 (20130101) C10M 2203/003 (20130101) C10M 2207/281 (20130101) C10M 2207/284 (20130101) Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions C10N 2030/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866744 | Pfleger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Brian F. Pfleger (Madison, Wisconsin); Nestor Jose Hernandez-Lozada (Jena, Germany); Costas Maranas (State College, Pennsylvania); Matthew Grisewood (Mountaintop, Pennsylvania) |
| ABSTRACT | Unnatural, mutated thioesterases having an amino acid sequence that is at least 80% identical to SEQ. ID. NO: 1 and having substitutions at one or more of amino acid positions I107, R108, L109, S122, M141, E142, Y145, and L146, gene constructs encoding and configured to express the mutated thioesterases in a transformed host cell and host cells transformed to contain the gene constructs. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/332186 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Original (OR) Class Enzymes C12Y 301/02002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866768 | Kartalov et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Emil P. Kartalov (Pasadena, California); Aditya Rajagopal (Orange, California); Axel Scherer (Pasadena, California) |
| ABSTRACT | This disclosure provides methods, systems, compositions, and kits for the multiplexed detection of a plurality of analytes in a sample. In some examples, this disclosure provides methods, systems, compositions, and kits wherein multiple analytes may be detected in a single sample volume by acquiring a cumulative measurement or measurements of at least one quantifiable component of a signal. In some cases, additional components of a signal, or additional signals (or components thereof) are also quantified. Each signal or component of a signal may be used to construct a coding scheme which can then be used to determine the presence or absence of any analyte. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/937464 |
| ART UNIT | 1672 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6851 (20130101) C12Q 1/6851 (20130101) C12Q 2537/101 (20130101) C12Q 2537/143 (20130101) C12Q 2537/165 (20130101) C12Q 2563/107 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Electric Digital Data Processing G06F 17/10 (20130101) G06F 17/11 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 25/00 (20190201) G16B 25/20 (20190201) G16B 40/00 (20190201) G16B 40/10 (20190201) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866804 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Nien-Hwa Linda Wang (West Lafayette, Indiana); Hoon Choi (Miami, Florida); David Harvey (West Lafayette, Indiana) |
| ABSTRACT | A process for the isolation and purification of substantially pure chemicals, including silica gel, sodium silicate, aluminum silicate, iron oxide, and rare earth elements (or rare earth metals, REEs), from massive industrial waste coal ash including a plurality of caustic extractions of coal ash at an elevated temperature, followed by an acidic treatment to dissolve aluminum silicate and REEs. Dissolved aluminum silicate is precipitated out by pH adjustment as a solid product while REEs remain in the solution. REEs are captured and enriched using an ion exchange column. Alternatively, the solution containing aluminum silicate and REEs is heated to produce silica gel, which is separated from the enriched REEs solution. REEs are then isolated and purified from the enriched solution to afford substantially pure individual REE by a ligand-assisted chromatography. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/536403 |
| ART UNIT | 1738 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/14 (20130101) C01B 33/26 (20130101) C01B 33/32 (20130101) Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 13/00 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 7/0693 (20130101) C01F 11/02 (20130101) C01F 11/24 (20130101) C01F 17/271 (20200101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/02 (20130101) C01G 49/06 (20130101) C01G 49/10 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/08 (20130101) C22B 3/10 (20130101) C22B 3/42 (20130101) C22B 3/44 (20130101) C22B 3/065 (20130101) C22B 7/02 (20130101) C22B 7/007 (20130101) Original (OR) Class C22B 21/0023 (20130101) C22B 59/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866847 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Fang Liu (New York, New York); Xiaoyang Zhu (New York, New York); James Hone (New York, New York); Sang Hoon Chae (New York, New York) |
| ABSTRACT | Systems and methods for generating one or more single crystal monolayers from two-dimensional van der Waals crystals are disclosed herein. Example methods include providing a bulk material including a plurality of van der Waals crystal layers, and exfoliating one or more single crystal monolayers of van der Waals crystal from the bulk material by applying a flexible and flat metal tape to a surface of the bulk material. In certain embodiments, the one or more single crystal monolayers can be assembled into an artificial lattice. The present disclosure also provides techniques for manufacturing flexible and flat metal tape for generating one or more single crystal monolayers from two-dimensional van der Waals crystals. The present disclosure also provides compositions for creating a macroscopic artificial lattice. In certain embodiments, the composition can include two or more macroscopic single crystal monolayers adapted from a bulk van der Waals crystal, where the single crystal monolayers are configured for assembly into an artificial lattice based on one or more properties. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/105105 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/02 (20130101) B32B 18/00 (20130101) B32B 37/18 (20130101) B32B 37/025 (20130101) B32B 43/006 (20130101) B32B 2315/02 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 39/06 (20130101) C01G 41/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/24 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/16 (20130101) C23C 14/30 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/46 (20130101) C30B 29/68 (20130101) C30B 33/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867631 | Peterman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OndaVia, Inc. (Hayward, California) |
| ASSIGNEE(S) | OndaVia, Inc. (Hayward, California) |
| INVENTOR(S) | Mark C. Peterman (Fremont, California); Merwan Benhabib (San Francisco, California); Samuel Kleinman (Oakland, California) |
| ABSTRACT | A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527828 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2200/04 (20130101) B01L 2200/12 (20130101) B01L 2200/0652 (20130101) B01L 2300/087 (20130101) B01L 2300/0627 (20130101) B01L 2300/0636 (20130101) B01L 2300/0654 (20130101) B01L 2300/0681 (20130101) B01L 2300/0867 (20130101) B01L 2400/0418 (20130101) B01L 2400/0421 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) G01J 3/18 (20130101) G01J 3/44 (20130101) G01J 3/0256 (20130101) G01J 3/0291 (20130101) G01J 3/4412 (20130101) G01J 2003/2866 (20130101) G01J 2003/2879 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/49 (20130101) G01N 21/63 (20130101) G01N 21/65 (20130101) Original (OR) Class G01N 21/66 (20130101) G01N 21/68 (20130101) G01N 21/276 (20130101) G01N 21/658 (20130101) G01N 21/4785 (20130101) G01N 27/44704 (20130101) G01N 27/44791 (20130101) G01N 30/6065 (20130101) G01N 30/6095 (20130101) G01N 33/18 (20130101) G01N 2021/651 (20130101) G01N 2021/656 (20130101) G01N 2030/0095 (20130101) G01N 2201/13 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867644 | Ros et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Alexandra Ros (Phoenix, Arizona); Daihyun Kim (Mesa, Arizona); Austin Echelmeier (Tempe, Arizona); Jorvani Cruz Villarreal (Tempe, Arizona); Ana Egatz-Gomez (Phoenix, Arizona); Sebastian Quintana (Phoenix, Arizona) |
| ABSTRACT | Methods and systems are provided for serial femtosecond crystallography for reducing the vast amount of waste of injected crystals practiced with traditional continuous flow injections. A micrometer-scale 3-D printed water-in-oil droplet generator device includes an oil phase inlet channel, an aqueous phase inlet channel, a droplet flow outlet channel, and two embedded non-contact electrodes. The inlet and outlet channels are connected internally at a junction. The electrodes comprise gallium metal injected within the 3-D printed device. Voltage across the electrodes generates water-in-oil droplets, determines a rate for a series of droplets, or triggers a phase shift in the droplets. An external trigger generates the droplets based on the frequency of an XFEL utilized in droplet detection, thereby synchronizing a series of droplets with x-ray pulses for efficient crystal detection. The generated droplets can be coupled to an SFX with XFEL experiment compatible with common liquid injector such as a GDVN. |
| FILED | Thursday, April 01, 2021 |
| APPL NO | 17/220357 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0241 (20130101) B01L 3/50273 (20130101) B01L 2300/0867 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20025 (20130101) Original (OR) Class G01N 2223/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867655 | Lillehoj et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Peter B. Lillehoj (East Lansing, Michigan); Xiyuan Liu (East Lansing, Michigan) |
| ABSTRACT | The disclosure relates to textile biosensors and related systems that can be used for in situ health monitoring and disease detection. The biosensors include a flexible or textile substrate, a working electrode embroidered thereon, a reference electrode embroidered thereon, optionally a counter electrode embroidered thereon, and an enzyme probe bound to the working electrode. The biosensors can be integrated directly onto fabrics and garments to provide lightweight, unobtrusive wearable sensing systems that do not compromise wearer mobility, comfort or attention. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 16/095989 |
| ART UNIT | 1759 — Fluid Handling and Dispensing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/6804 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/006 (20130101) Enzymes C12Y 101/03004 (20130101) C12Y 113/12004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/301 (20130101) G01N 27/3272 (20130101) G01N 27/3277 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867700 | Jarrold et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| INVENTOR(S) | Martin F. Jarrold (Bloomington, Indiana); Corrine A. Lutomski (Bloomington, Indiana) |
| ABSTRACT | The present disclosure relates to methods of identifying components present in intact lipoprotein particles. Methods provided include single particle mass spectrometry, such as charge detection mass spectrometry (CDMS). Distinct subtypes and subpopulations that exist within lipoprotein density classes are determined based on simultaneously measured m/z and charge of ionized lipoprotein particles. |
| FILED | Tuesday, April 11, 2023 |
| APPL NO | 18/298514 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/6848 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 49/025 (20130101) H01J 49/40 (20130101) H01J 49/0068 (20130101) H01J 49/4225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867937 | Rubin et al. |
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| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Noah A. Rubin (Cambridge, Massachusetts); Federico Capasso (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides an optical component, which may be a metasurface grating, including (a) a substrate; and (b) an array of subwavelength-spaced phase-shifting elements, which are tessellated on the substrate to produce, when illuminated with a polarized incident light, a diffracted light beam with a distinct polarization state for each of a finite number of diffraction orders, wherein the finite number is 2 or more. |
| FILED | Wednesday, October 13, 2021 |
| APPL NO | 17/500913 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) Optical Elements, Systems, or Apparatus G02B 5/3025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11868479 | Lysecky et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); JOHANNES KEPLER UNIVERSITY LINZ (Linz, Austria) |
| INVENTOR(S) | Roman Lysecky (Tucson, Arizona); Jerzy Rozenblit (Tucson, Arizona); Johannes Sametinger (Linz, Austria); Aakarsh Rao (Tucson, Arizona); Nadir Carreon (Tucson, Arizona) |
| ABSTRACT | A security framework for life-critical and safety-critical devices, specifically medical devices, using: a) runtime, adaptive methods that dynamically assess the risk of newly discovered vulnerabilities and threats, and b) automatic mitigation methods that reduce system risk by seamlessly reconfiguring the device to operate within different execution modes. This technology automatically isolates threats by disabling affected system components. A multi-modal software design uses adaptive software in which operational modes have monotonically decreasing cumulative risk. Formal risk models are used to model the individual risk of accessing or controlling system components and to automatically calculate the cumulative risk of software modes. The automated detection of potential threats by the system or reporting of known vulnerabilities will dynamically change the system risk. To support an accurate and fine grained adaptive risk model, novel statistical methods non-intrusively detect potential threats, isolate the threat to a specific component, and estimate the threat probability. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 17/290627 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0031 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14276 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/362 (20130101) A61N 1/37223 (20130101) Electric Digital Data Processing G06F 21/566 (20130101) G06F 21/577 (20130101) Original (OR) Class G06F 2221/034 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/17 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11868771 | Siskind et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); NATIONAL UNIVERSITY OF IRELAND, MAYNOOTH (Maynooth, Ireland) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jeffrey Mark Siskind (West Lafayette, Indiana); Barak Avrum Pearlmutter (Dublin, Ireland) |
| ABSTRACT | A system and method which allows the basic checkpoint-reverse-mode AD strategy (of recursively decomposing the computation to reduce storage requirements of reverse-mode AD) to be applied to arbitrary programs: not just programs consisting of loops, but programs with arbitrarily complex control flow. The method comprises (a) transforming the program into a formalism that allows convenient manipulation by formal tools, and (b) introducing a set of operators to allow computations to be decomposed by running them for a given period of time then pausing them, while treating the paused program as a value subject to manipulation. |
| FILED | Tuesday, August 09, 2022 |
| APPL NO | 17/818396 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/60 (20130101) G06F 7/544 (20130101) G06F 9/461 (20130101) G06F 9/30036 (20130101) Original (OR) Class G06F 11/36 (20130101) G06F 17/10 (20130101) G06F 17/13 (20130101) G06F 17/17 (20130101) Computer Systems Based on Specific Computational Models G06N 5/01 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11868862 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | Zhongfei Zhang (Vestal, New York); Shuangfei Zhai (Binghamton, New York) |
| ABSTRACT | A method of modelling data, comprising: training an objective function of a linear classifier, based on a set of labeled data, to derive a set of classifier weights; defining a posterior probability distribution on the set of classifier weights of the linear classifier; approximating a marginalized loss function for an autoencoder as a Bregman divergence, based on the posterior probability distribution on the set of classifier weights learned from the linear classifier; and classifying unlabeled data using the autoencoder according to the marginalized loss function. |
| FILED | Sunday, December 19, 2021 |
| APPL NO | 17/555493 |
| ART UNIT | 2198 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 18/214 (20230101) G06F 18/2411 (20230101) Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) G06N 3/047 (20230101) G06N 3/084 (20130101) G06N 7/01 (20230101) G06N 20/10 (20190101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/764 (20220101) G06V 10/774 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11869633 | Iyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ravishankar Krishnan Iyer (Champaign, Illinois); Arjun Prasanna Athreya (Urbana, Illinois); Richard Merle Weinshilboum (Rochester, Minnesota); Liewei Wang (Rochester, Minnesota); William Victor Bobo (Rochester, Minnesota); Mark Andrew Frye (Rochester, Minnesota) |
| ABSTRACT | The present disclosure provides methods for accurately predicting the dynamics of symptom response to drugs or other interventions for the treatment of major depressive disorder or other psychological conditions. These methods can allow for a shortening of the time period necessary for the evaluation of a drug or other therapeutic intervention. These predictive methods are based on measured and/or self-reported symptom severity measures at two or more points in time. These measures are then discretized into symptom classes (e.g., low, moderate, severe) and the symptom classes are then applied to the predictive model to predict the progression of symptoms and/or the effectiveness of a drug or other therapeutic intervention. The predictive methods may be augmented by metabolomics data, genomics data, or other objective measures taken from a patient, allowing the use of objective physiological measures to diagnosis and treat psychological conditions heretofore diagnosed and assessed using only subjective, self-reported measures. |
| FILED | Friday, December 14, 2018 |
| APPL NO | 16/221073 |
| ART UNIT | 1671 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 40/00 (20190201) Original (OR) Class G16B 40/20 (20190201) G16B 40/30 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/30 (20190201) G16C 20/70 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870067 | Banerjee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| INVENTOR(S) | Sarbajit Banerjee (College Station, Texas); Justin L. Andrews (College Station, Texas) |
| ABSTRACT | A highly scalable process has been developed for stabilizing large quantities of the zeta-polymorph of V2O5, a metastable kinetically trapped phase, with high compositional and phase purity. The process utilizes a beta-Cux V2O5 precursor which is synthetized from solution using all-soluble precursors. The copper can be leached from this structure by a room temperature post-synthetic route to stabilize an empty tunnel framework entirely devoid of intercalating cations. The metastable ζ-V2O5 thus stabilized can be used as a monovalent-(Li, Na) or multivalent-(Mg, Ca, Al) ion battery cathode material. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/956775 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 31/02 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2002/74 (20130101) C01P 2002/77 (20130101) C01P 2002/78 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/16 (20130101) C01P 2006/40 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 15/0065 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/485 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11871233 | Pierson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Timothy J. Pierson (Hanover, New Hampshire); Ronald Peterson (Brattleboro, Vermont); David F. Kotz (Lyme, New Hampshire) |
| ABSTRACT | A single-antenna device includes a single antenna, at least one processor, and at least one memory. The single-antenna device is operable to receive a signal including at least one frame. Each of said frame includes a repeating portion. The single-antenna device determines a difference of phase and amplitude of the repeating portion and further determines whether the signal is transmitted from a trusted source based at least in part on the difference of phase and amplitude of the repeating portion. |
| FILED | Friday, April 26, 2019 |
| APPL NO | 17/050764 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0284 (20130101) G01S 2205/07 (20200501) Information and Communication Technology Specially Adapted for the Internet of Things [IOT] G16Y 40/50 (20200101) G16Y 40/60 (20200101) Wireless Communication Networks H04W 4/80 (20180201) H04W 12/122 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11866198 | Brockers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Roland Brockers (Pasadena, California); Stephan Michael Weiss (Lenzburg, Switzerland); Danylo Malyuta (Seattle, Washington); Christian Brommer (Werne, Germany); Daniel Robert Hentzen (Zurich, Switzerland) |
| ABSTRACT | A method and system provide the ability to autonomously operate an unmanned aerial system (UAS) over long durations of time. The UAS vehicle autonomously takes off from a take-off landing-charging station and autonomously executes a mission. The mission includes data acquisition instructions in a defined observation area. Upon mission completion, the UAS autonomously travels to a target landing-charging station and performs an autonomous precision landing on the target landing-charging station. The UAS autonomously re-charges via the target landing-charging station. Once re-charged, the UAS is ready to execute a next sortie. When landed, the UAS autonomously transmits mission data to the landing-charging station for in situ or cloud-based data processing. |
| FILED | Tuesday, October 29, 2019 |
| APPL NO | 16/667655 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 53/12 (20190201) B60L 53/14 (20190201) B60L 2200/10 (20130101) Aeroplanes; Helicopters B64C 39/024 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 47/08 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/362 (20130101) Original (OR) Class B64F 5/60 (20170101) Unmanned aerial vehicles [UAV]; equipment therefor B64U 10/13 (20230101) B64U 30/20 (20230101) B64U 2101/00 (20230101) B64U 2101/30 (20230101) B64U 2201/10 (20230101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11866569 | Agarwal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arvind Agarwal (Miami, Florida); Kazue Orikasa (Miami, Florida); Ambreen Nisar (Miami, Florida); Tony Thomas (Miami, Florida); Preyojon Dey (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Arvind Agarwal (Miami, Florida); Kazue Orikasa (Miami, Florida); Ambreen Nisar (Miami, Florida); Tony Thomas (Miami, Florida); Preyojon Dey (Miami, Florida) |
| ABSTRACT | Foams and methods of fabricating and using the same are provided. The foams can be free-standing and rigid and can be used as, for example, nanofiller networks. The shape and size of the foam pore interconnected network can be tailorable/tailored. The foams can be, for example, transition metal dichalcogenide (TMD) foams with a layered structure (e.g., tungsten sulfide (WS2) foams). A freeze-drying-based method can be used to fabricate bulk porous foam, which can be used for, e.g., polymer nanocomposites. A vacuum-assisted infiltration procedure can be used to fabricate a foam-polymer nanocomposite. |
| FILED | Tuesday, May 30, 2023 |
| APPL NO | 18/325188 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) C08J 2205/10 (20130101) C08J 2383/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/11 (20180101) C08K 3/30 (20130101) Original (OR) Class C08K 2003/3009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11867319 | Alexeenko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Alina Alexeenko (West Lafayette, Indiana); Anthony George Cofer (Lafayette, Indiana); Stephen Douglas Heister (West Lafayette, Indiana) |
| ABSTRACT | A microfabricated valve with no moving parts. In one embodiment, the valve includes a reservoir of a liquid that is in fluid communication with an outlet channel having a throat that is less than 100 microns wide. Preferably, the channel is an elongated slit. The configuration of channel is adapted and configured such that surface tension of the liquid prevents flow out of the channel. A heater increases the temperature of the meniscus of the fluid, until a portion of the fluid is ejected from the channel. The ejection of the fluid creates both a thrusting effect and a cooling effect. |
| FILED | Monday, May 03, 2021 |
| APPL NO | 17/306811 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/10 (20130101) B64G 1/50 (20130101) B64G 1/401 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 99/0017 (20130101) Original (OR) Class F16K 99/0036 (20130101) F16K 2099/0092 (20130101) F16K 2099/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11870183 | Shasho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeybee Robotics, LLC (Longmont, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey I. Shasho (Brooklyn, New York); Jonah E. Saltzman (Brooklyn, New York) |
| ABSTRACT | A joint system for constructing orbital and extra-terrestrial structures includes a node receptacle having a node surface and a finger receiver projecting outwardly of the node surface, and a strut element including a support member, a finger element shiftably supported on the support member, a shell system shiftably supported on the support member and connected to the finger element, and an actuator mounted to the support member and operatively connected with the shell system. The actuator is operable to shift the finger element and the shell system into contact with the node receptacle. The finger element cooperates with the finger receiver to form a first load path and the shell system cooperating with the node surface to form a second load path. |
| FILED | Monday, August 24, 2020 |
| APPL NO | 17/000471 |
| ART UNIT | 3649 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 99/00 (20220801) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 13/502 (20130101) H01R 13/62927 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11871252 | Barsoum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Constellation Designs, LLC (Anaheim, California) |
| ASSIGNEE(S) | Constellation Designs, LLC (Wayne, Pennsylvania) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Thursday, May 26, 2022 |
| APPL NO | 17/804307 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11865062 | Higgins |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Brian L. Higgins (Los Altos, California) |
| ABSTRACT | A guide system is provided that uses a plurality of sensors to identify and determine a clear path for an ambulatory vision impaired person. The system includes one or more wheels that rotate to propel the system, a platform supported by the one or more wheels and housing a processor, a rigid harness with a haptic feedback grip that is positioned to be grasped by an operator, and one or more sensors configured to sense information about the environment. In operation, the processor analyzes information sensed by the sensors to identify object in the path of the guide system and sends messages to the operator to allow the operator to avoid the identified objects. The messages may be sent to the operator via the haptic feedback grip or audibly via a speaker or via a wireless connection to a haptic or audio device being worn by the operator. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 16/341693 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) A61H 3/02 (20130101) A61H 3/04 (20130101) A61H 3/06 (20130101) A61H 3/061 (20130101) Original (OR) Class A61H 2003/063 (20130101) A61H 2201/1215 (20130101) A61H 2201/5048 (20130101) A61H 2201/5064 (20130101) A61H 2201/5069 (20130101) A61H 2201/5076 (20130101) A61H 2201/5079 (20130101) A61H 2201/5084 (20130101) A61H 2201/5092 (20130101) A61H 2201/5097 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/931 (20130101) G01S 15/86 (20200101) G01S 15/88 (20130101) G01S 15/931 (20130101) G01S 17/88 (20130101) G01S 17/931 (20200101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0238 (20130101) Electric Digital Data Processing G06F 3/016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865125 | Farese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); UNITED STATES DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Robert Vito Farese (St. Petersburg, Florida); Mini Paliyath Sajan (Wesley Chapel, Florida); Margaret Genevieve Higgs (St. Petersburg, Florida) |
| ABSTRACT | Provided herein are formulations effective for and methods of treating or preventing a neurodegenerative disorder in a subject in need thereof that can include administering an amount of an aPKC inhibitor to a subject in need thereof. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 17/554924 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/675 (20130101) Original (OR) Class A61K 33/242 (20190101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Enzymes C12Y 304/23046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865328 | Hampstead et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin Hampstead (Ann Arbor, Michigan); Allena Holzworth (Ann Arbor, Michigan); Kevin Kramer (Ann Arbor, Michigan); Alexander Rothmann (Ann Arbor, Michigan); Shannon Ryan (Ann Arbor, Michigan) |
| ABSTRACT | A customizable headgear assembly for neuropsychological and neurological treatment, monitoring, or testing of a patient. The headgear assembly comprising a structural frame having a plurality of anatomical landmark tabs each individually configured to be located upon an anatomical landmark of a patient's head. The structural frame having first and second portions releasably coupled to enable the first and second portions to be at least partially separated for placement and removal from the patient's head. A plurality of electrode holders being operable coupled to the structural frame each configured to locate an electrode upon a predetermined neurological position of the patient. |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/188437 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/291 (20210101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/20 (20130101) A61N 1/0456 (20130101) Original (OR) Class A61N 1/0476 (20130101) A61N 1/0484 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11865033 | Maier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Reia, LLC (Lyme, New Hampshire) |
| ASSIGNEE(S) | Reia, LLC (Lyme, New Hampshire) |
| INVENTOR(S) | Kaitlin E. Maier (Darien, Connecticut); Meegan P. Daigler (Portland, Maine); Ariana M. Sopher (Somerville, Massachusetts) |
| ABSTRACT | A pessary providing various structures, parts, and components to enable the pessary to remain deployed in a supportive position so that it may reliably provide the desired supportive capabilities. A ridge structure prevents over-rotation of the supportive members. The pessary can be formed preferably by injection molding where the mold has at least one insert. The geometry of the pessary can enable the pessary to have the required stiffness, flexibility, hinged capability, and softness where needed to achieve a pessary that is superior to prior art pessaries. |
| FILED | Wednesday, May 26, 2021 |
| APPL NO | 17/331312 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 6/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11865594 | Quigley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Higganum, Connecticut); Nicole Neff (North Potomac, Maryland); Jack Rowbottom (Swansea, Massachusetts) |
| ABSTRACT | Systems and methods for controlling extraction of landfill gas from a landfill via a gas extraction system comprising a plurality of wells are provided herein. In some embodiments, the method comprises obtaining a concentration of a greenhouse gas measured a distance above a surface of a region comprising the plurality of wells; determining whether the measure of the concentration of the greenhouse gas is greater than a first threshold; and in response to determining that the measure of the concentration of the greenhouse gas is greater than the first threshold, increasing a flow rate of landfill gas being extracted from at least one well of the plurality of wells. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/540833 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class B09B 2101/25 (20220101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/30 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11865171 | Dominowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zoetis Services LLC (Parsippany, New Jersey); United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | Zoetis Services LLC (Parsippany, New Jersey); United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Paul Joseph Dominowski (Kalamazoo, Michigan); John Morgan Hardham (Kalamazoo, Michigan); James Alan Jackson (Kalamazoo, Michigan); Cyril Gerard Gay (Bethesda, Maryland); Luis Leandro Rodriguez (Niantic, Connecticut); Peter William Krug (East Setauket, New York); Aida Elizabeth Rieder (Westbrook, Connecticut) |
| ABSTRACT | Compositions for prevention of Foot and Mouth Disease (FMD) are provided, comprising an antigen component in the amount equivalent to 0.5-20 μg FMD virus and an adjuvant component comprising oil, an immunostimulatory oligonucleotide, and a polycationic carrier. Methods of using the composition, as well as the methods of reducing FMD persistence are also provided. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180223 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 39/135 (20130101) Original (OR) Class A61K 2039/552 (20130101) A61K 2039/555 (20130101) A61K 2039/5252 (20130101) A61K 2039/55505 (20130101) A61K 2039/55511 (20130101) A61K 2039/55561 (20130101) A61K 2039/55566 (20130101) A61K 2039/55583 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/32034 (20130101) C12N 2770/32134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11867775 | Elmquist et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE, NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland) |
| ASSIGNEE(S) | Government of the United States of America (Gaithersburg, Maryland); University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Randolph Elmquist (Gaithersburg, Maryland); Albert Rigosi (Rockville, Maryland); Mattias Kruskopf (Washington Grove, Maryland) |
| ABSTRACT | A quantum Hall resistance apparatus is to improve resistance standards and includes a substrate, a graphene epitaxially grown on the substrate and having a plurality of first contact patterns at edges of the graphene, a plurality of contacts, each including a second contact pattern and configured to connect to a corresponding first contact pattern, and a protective layer configured to protect the graphene and to increase adherence between the first contact patterns and the second contact patterns. The contacts become a superconductor at a temperature lower than or equal to a predetermined temperature and under up to a predetermined magnetic flux density. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 17/435807 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/07 (20130101) G01R 33/035 (20130101) G01R 33/0052 (20130101) Original (OR) Class Electric solid-state devices not otherwise provided for H10N 60/81 (20230201) H10N 60/85 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11869350 | Hourdos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | John Hourdos (Minneapolis, Minnesota); Gordon Parikh (Minneapolis, Minnesota) |
| ABSTRACT | A computer system includes a memory and a processor. The processor executes instructions to perform steps that include receiving a message from an asset tracking device, the message comprising position information for the asset tracking device and a traffic control device type for a traffic control device that the asset tracking device is attached to. The processor uses the received message to determine a road that the traffic control device is positioned on and a location of the traffic control device along the road. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538237 |
| ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0054 (20130101) G01S 5/0242 (20130101) Electric Digital Data Processing G06F 3/04817 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06313 (20130101) G06Q 50/08 (20130101) Traffic Control Systems G08G 1/0955 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 11866376 | Lashmore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of New Hampshire (Durham, New Hampshire) |
| ASSIGNEE(S) | University of New Hampshire (Durham, New Hampshire) |
| INVENTOR(S) | David S. Lashmore (Lebanon, New Hampshire); Tyler Bennett (Durham, New Hampshire) |
| ABSTRACT | A method and apparatus for producing boron nitride nanotubes and continuous boron nitride nanotube yarn or tapes is provided. The apparatus includes rotating reaction tubes that allow for continuous chemical vapor deposition of boron nitride nanotubes. The rotation of the reaction tubes allows the boron nitride nanotubes to be spun into yarns or made into tapes, without post process or external rotation or spinning of the gathered nanotubes. Boron nitride nanotube yarns or tapes of great length can be produced as a result, thereby providing industry with a readily useable format for this type of material. Dopants such as carbon can be added to engineer the band gap of the nanotubes. Catalysts may be formed outside or inside the reactor. |
| FILED | Tuesday, October 29, 2019 |
| APPL NO | 16/666580 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0641 (20130101) C01B 21/0646 (20130101) C01B 21/0648 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2004/54 (20130101) C01P 2004/136 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/80 (20130101) Original (OR) Class C04B 35/5831 (20130101) C04B 35/6229 (20130101) C04B 2235/524 (20130101) C04B 2235/526 (20130101) C04B 2235/5264 (20130101) C04B 2235/5284 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/02 (20130101) D02G 3/16 (20130101) D02G 3/442 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/14 (20130101) D10B 2507/00 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 1/02 (20130101) F41H 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11867754 | Lal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York); Christopher Batten (Ithaca, New York) |
| ABSTRACT | A system, comprising: (i) an interposer layer; (ii) a circuit layer positioned on the interposer layer and comprising a plurality of sonically-enabled pads; and (iii) an interrogator layer positioned on the circuit layer and comprising a plurality of ultrasonic transducers configured to sonically interrogate the circuit layer; wherein the sonically-enabled pads are configured to generate an electrical signal in response to sonic interrogation from the interrogator layer, if the sonically-enabled pad is functional. |
| FILED | Tuesday, July 17, 2018 |
| APPL NO | 16/631590 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/00 (20130101) G01N 29/22 (20130101) G01N 29/225 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 31/303 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11865176 | Wong |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kwok-Kin Wong (Arlington, Massachusetts) |
| ABSTRACT | The present invention provides methods of treating cancer by combination therapy with CDK4/6 inhibitors and immune checkpoint inhibition. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 16/347999 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 39/39541 (20130101) Original (OR) Class A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, January 09, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240109.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page