FedInvent™ Patents

Patent Details for Tuesday, January 16, 2024 

This page was updated on Wednesday, January 17, 2024 at 06:46 PM GMT

Department of Health and Human Services (HHS) 

US 11871978 Browning et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) BOISE STATE UNIVERSITY (Boise, Idaho)
ASSIGNEE(S) Boise State University (Boise, Idaho)
INVENTOR(S) Jim Browning (Boise, Idaho);  Ken Cornell (Boise, Idaho)
ABSTRACT The disclosure relates to the medical device field. In particular, the disclosure relates to a dynamically controlled plasma scalpel in combination with an imaging system to selectively remove biofilm while minimizing damage to healthy tissue. Systems and apparatuses according to the disclosure include: (1) dynamically controlled plasma scalpel, (2) biofilm imaging system, (3) computer control system, (4) three-dimensional scalpel positioning stage, and (5) biofilm detritus removal system.
FILED Thursday, April 19, 2018
APPL NO 15/956895
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/042 (20130101) Original (OR) Class
A61B 34/30 (20160201)
A61B 2017/00057 (20130101)
A61B 2018/00291 (20130101)
A61B 2018/00452 (20130101)
A61B 2018/00583 (20130101)
A61B 2018/00642 (20130101)
A61B 2018/00738 (20130101)
A61B 2090/373 (20160201)
A61B 2090/395 (20160201)
A61B 2090/3735 (20160201)
A61B 2090/3933 (20160201)
A61B 2218/007 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/14 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/40 (20130101)

Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion
B60B 27/02 (20130101)

Vehicle Suspension Arrangements
B60G 7/02 (20130101)
B60G 2204/418 (20130101)
B60G 2206/50 (20130101)

Vehicle Brake Control Systems or Parts Thereof; Brake Control Systems or Parts Thereof, in General; Arrangement of Braking Elements on Vehicles in General; Portable Devices for Preventing Unwanted Movement of Vehicles; Vehicle Modifications to Facilitate Cooling of Brakes
B60T 1/06 (20130101)

Motor Vehicles; Trailers
B62D 7/18 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/02 (20130101)
H05H 1/46 (20130101)
H05H 1/48 (20130101)
H05H 1/466 (20210501)
H05H 1/475 (20210501)
H05H 1/2406 (20130101)
H05H 2245/34 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872022 Franceschini et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Maria Angela Franceschini (Charlestown, Massachusetts);  Stefan Carp (Boston, Massachusetts);  Davide Tamborini (Charlestown, Massachusetts);  David Boas (Charlestown, Massachusetts);  Bruce Rosen (Charlestown, Massachusetts);  Megan Blackwell (Charlestown, Massachusetts);  Oleg Shatrovoy (Charlestown, Massachusetts)
ABSTRACT An apparatus, including: a probe to interface with a surface of a tissue; a light source optically coupled to the probe, the light source directing light of at least 1000 nm into the tissue; a detector optically coupled to the probe, the detector to detect light based on scattering of light from the light source in the tissue, and the detector having a light sensitivity in a range of at least 1000 nm; a processor coupled to the detector, the processor to: receive a signal from the detector corresponding to the detected light from the light source, and determine a blood flow measurement from the region of interest using diffuse correlation spectroscopy based on the signal.
FILED Monday, February 18, 2019
APPL NO 16/970670
ART UNIT 2878 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0261 (20130101) Original (OR) Class
A61B 2562/0233 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/44 (20130101)
G01J 2001/448 (20130101)
G01J 2001/4453 (20130101)
G01J 2001/4466 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/107 (20130101)
H01L 31/109 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872029 Kayyali et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Cleveland Medical Devices Inc. (Cleveland, Ohio)
ASSIGNEE(S) Cleveland Medical Devices Inc. (Cleveland, Ohio)
INVENTOR(S) Hani Kayyali (Shaker Heights, Ohio);  Robert Schmidt (Ft. Myers, Florida);  Mohammad Modarres-Zadeh (Tampa, Florida);  Brian Kolkowski (Leroy, Ohio)
ABSTRACT The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to method of sleep diagnosis and treatment.
FILED Friday, February 03, 2023
APPL NO 18/105277
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/085 (20130101) Original (OR) Class
A61B 5/02055 (20130101)
A61B 5/4815 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 16/0051 (20130101)
A61M 16/0069 (20140204)
A61M 2016/0027 (20130101)
A61M 2016/0039 (20130101)
A61M 2202/0208 (20130101)
A61M 2205/3553 (20130101)
A61M 2205/3561 (20130101)
A61M 2205/3584 (20130101)
A61M 2205/3592 (20130101)
A61M 2230/04 (20130101)
A61M 2230/10 (20130101)
A61M 2230/14 (20130101)
A61M 2230/60 (20130101)
A61M 2230/202 (20130101)
A61M 2230/205 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872078 Waag et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Habico, Inc. (Honey Falls, New York)
ASSIGNEE(S)
INVENTOR(S) Robert C. Waag (Ocean City, New Jersey);  Jeffrey P. Astheimer (Honey Falls, New York)
ABSTRACT A system and method for capturing ultrasound signals from a hemispheric imaging region (e.g., by a stationary array of transducer elements arranged in the shape of a faceted hemisphere) and estimating scattering measurements that would be made by a virtual array in the opposite hemisphere (e.g., by a network of processors that receive and process the transmitted ultrasound signals in parallel) by forming an initial estimate of a medium variation for each of a plurality of subvolumes in the scattering object to form an estimated object, calculating residual scattering by using a difference between a scattering response calculated for the estimated object and measured ultrasound signals received from the scattering object, forming an initial three-dimensional image of the scattering object, and extrapolating a difference between the scattering response calculated for the estimated object and the measured ultrasound signals received from the scattering object.
FILED Wednesday, July 20, 2022
APPL NO 17/869443
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/08 (20130101)
A61B 8/14 (20130101) Original (OR) Class
A61B 8/406 (20130101)
A61B 8/483 (20130101)
A61B 8/0825 (20130101)
A61B 8/4281 (20130101)
A61B 8/4483 (20130101)
A61B 8/4494 (20130101)
A61B 8/5207 (20130101)
A61B 8/5269 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 15/8915 (20130101)
G01S 15/8929 (20130101)
G01S 15/8959 (20130101)
G01S 15/8977 (20130101)
G01S 15/8993 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872194 Hu
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Zhiwei Hu (Dublin, Ohio)
ABSTRACT Disclosed are methods and compositions related to immunoconjugates. Particularly disclosed are immunoconjugates that comprise the Fc portion of IgG3 as well as Factor VII light chain or Factor VII. Also disclosed is an immunoconjugate protein, wherein said immunoconjugate protein comprises a hybrid Fc region of an IgG1 and an IgG3 immunoglobulin conjugated to Factor VII. These immunoconjugates can target Tissue Factor (TF) expressing cells.
FILED Wednesday, March 14, 2018
APPL NO 16/494177
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/4846 (20130101) Original (OR) Class

Peptides
C07K 16/36 (20130101)
C07K 2317/72 (20130101)
C07K 2317/73 (20130101)
C07K 2317/94 (20130101)

Enzymes
C12Y 304/21021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872200 Kaufman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Daniel L Kaufman (Los Angeles, California);  Jide Tian (Los Angeles, California)
ABSTRACT In certain embodiments methods are provided for the therapeutic or prophylactic amelioration of one or more symptoms or disorders associated with metabolic syndrome. In various embodiments the methods involve administering to a subject in need thereof, a GABA receptor agonist, in an amount sufficient to ameliorate said one or more symptoms. In certain embodiments methods are provided for the prophylaxis or treatment of type I diabetes and related pathologies that involve the use of GABA or GABA agonists in combination with certain other compounds (e.g., one more antigens (e.g., GAD) that have a therapeutic effect in type I diabetes and/or an anti-CD3 antibody, an anti-CD20 antibody, exendin-4, and/or or a pro-insulin therapeutic).
FILED Monday, March 22, 2021
APPL NO 17/208064
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/197 (20130101) Original (OR) Class
A61K 31/197 (20130101)
A61K 31/4465 (20130101)
A61K 31/4465 (20130101)
A61K 38/2013 (20130101)
A61K 39/0008 (20130101)
A61K 39/39 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872215 Boons
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia)
ASSIGNEE(S) University of Georgia Research Foundation, Inc. (Athens, Georgia)
INVENTOR(S) Geert-Jan Boons (Athens, Georgia)
ABSTRACT Compounds, compositions, and methods are provided for covalently linking an antibody or an antibody fragment to a cargo molecule, such as a therapeutic or a diagnostic agent, using a combination of enzymatic glycan remodeling and click chemistry. The method allows a cargo molecule to be selectively and efficiently attached post-translationally to an antibody or an antibody fragment. Also provided are antibody drug conjugates, methods of making, and uses thereof.
FILED Friday, January 22, 2021
APPL NO 17/155663
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/4188 (20130101) Original (OR) Class
A61K 47/6803 (20170801)
A61K 47/6809 (20170801)
A61K 47/6849 (20170801)
A61K 49/0043 (20130101)
A61K 49/0058 (20130101)

Peptides
C07K 16/00 (20130101)
C07K 16/2803 (20130101)
C07K 2317/41 (20130101)
C07K 2317/92 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872241 Zwicker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts)
INVENTOR(S) Jeffrey I. Zwicker (Boston, Massachusetts);  Bruce Furie (Boston, Massachusetts);  Jack Davis Stopa (Boston, Massachusetts);  Robert Flaumenhaft (Boston, Massachusetts)
ABSTRACT The present invention relates to methods for reducing soluble P-selectin and major thrombotic events in cancer patients.
FILED Tuesday, November 26, 2019
APPL NO 16/696280
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/45 (20130101)
A61K 31/352 (20130101)
A61K 31/375 (20130101)
A61K 31/519 (20130101)
A61K 31/7048 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872243 Ramunas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) John Ramunas (Menlo Park, California);  Eduard Yakubov (Houston, Texas);  Helen M. Blau (Menlo Park, California);  John Cooke (Houston, Texas)
ABSTRACT Compounds and compositions for the transient expression of exogenous telomerase activity in a cell are provided. The compounds and compositions, which relate to a ribonucleic acid coding for a telomerase reverse transcriptase, are useful in the extension of telomeres in cells needing such treatment. Such cells include, for example, cells that contain shortened telomeres and cells from subjects that may benefit from telomere extension, for example subjects that suffer from, or are at risk of suffering from, age-related or other illnesses. Also provided are methods of extending telomeres through the administration of the provided compounds and compositions to animal cells, either in vitro or in vivo, and kits including the compounds or compositions and instructions for use.
FILED Monday, January 06, 2020
APPL NO 16/735683
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101) Original (OR) Class
A61K 38/45 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1276 (20130101)
C12N 15/52 (20130101)

Enzymes
C12Y 207/07049 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872248 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Tong Zhang (Lebanon, New Hampshire);  Charles L. Sentman (Grantham, New Hampshire)
ABSTRACT The invention is directed to T cells and other cells that express chimeric NK-p30 receptors (“chimeric NKp30 T cells”), methods of making and using chimeric NKp30 T cells, and methods of using these chimeric NKp30 T cells, isolated populations thereof, and compositions comprising the same. In another aspect, said chimeric NKp30 T cells are further designed to express a functional non-TCR receptor. The disclosure also pertains to methods of making said chimeric NKp30 T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said chimeric NKp30 T cells, populations thereof, or compositions comprising the same.
FILED Tuesday, May 26, 2020
APPL NO 16/882800
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class
A61K 38/00 (20130101)

Peptides
C07K 14/70503 (20130101)
C07K 14/70521 (20130101)
C07K 14/70575 (20130101)
C07K 14/70578 (20130101)
C07K 14/70596 (20130101)
C07K 16/2803 (20130101)
C07K 2319/00 (20130101)
C07K 2319/03 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0636 (20130101)
C12N 15/00 (20130101)
C12N 15/62 (20130101)
C12N 2800/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872250 Shi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S) Yufang Shi (Belle Mead, New Jersey);  Guangwen Ren (Piscataway, New Jersey);  Liying Zhang (Belle Mead, New Jersey)
ABSTRACT The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs).
FILED Friday, January 15, 2021
APPL NO 17/150574
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/28 (20130101) Original (OR) Class
A61K 35/28 (20130101)
A61K 38/20 (20130101)
A61K 38/191 (20130101)
A61K 38/191 (20130101)
A61K 38/212 (20130101)
A61K 38/215 (20130101)
A61K 38/217 (20130101)
A61K 38/217 (20130101)
A61K 38/1825 (20130101)
A61K 38/1841 (20130101)
A61K 38/2006 (20130101)
A61K 38/2006 (20130101)
A61K 45/06 (20130101)
A61K 2035/122 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/02 (20180101)
A61P 37/04 (20180101)
A61P 37/06 (20180101)

Peptides
C07K 14/50 (20130101)
C07K 14/52 (20130101)
C07K 14/56 (20130101)
C07K 14/57 (20130101)
C07K 14/495 (20130101)
C07K 14/525 (20130101)
C07K 14/545 (20130101)
C07K 14/565 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0018 (20130101)
C12N 5/0607 (20130101)
C12N 5/0662 (20130101)
C12N 5/0663 (20130101)
C12N 5/0665 (20130101)
C12N 2500/05 (20130101)
C12N 2501/10 (20130101)
C12N 2501/15 (20130101)
C12N 2501/24 (20130101)
C12N 2501/25 (20130101)
C12N 2501/115 (20130101)
C12N 2501/2301 (20130101)
C12N 2501/2317 (20130101)
C12N 2502/1114 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872251 Marban et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Cedars-Sinai Medical Center (Los Angeles, California)
ASSIGNEE(S) Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S) Eduardo Marban (Santa Monica, California);  Romain Gallet (Paris, France)
ABSTRACT Heart failure with preserved ejection fraction (HFpEF) is a disease condition characterized by heart failure (HF) signs and symptoms, but with normal or near normal left ventricular ejection fraction (LVEF) and is not responsive to standard therapy for treatment of HF. Described herein are compositions and methods related to use of cardiosphere derived cells (CDCs) and their exosomes to improve left ventricular structure, function and overall outcome. Administration of CDCs led to improved LV relaxation, lower LV end-diastolic pressure, decreased lung congestion and enhanced survival. Lower risk of arrhythmias in HFpEF was also observed following CDC administration. Improvement of diastolic dysfunction following administration of CDC-derived exosomes was observed, along with decreased mortality. In view of these salutary effects, CDCs and CDC-derived exosomes are beneficial in the treatment of HFpEF.
FILED Wednesday, September 08, 2021
APPL NO 17/469441
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 35/34 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/04 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0657 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872255 Balani et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Forsyth Dental Infirmary for Children (Cambridge, Massachusetts)
ASSIGNEE(S) Forsyth Dental Infirmary for Children (Cambridge, Massachusetts)
INVENTOR(S) Pooja Balani (Melrose, Massachusetts);  Felicitas Bidlack (Somerville, Massachusetts);  Xuesong He (Cypress, California);  Megan Pugach-Gordon (Medford, Massachusetts);  Wenyuan Shi (Winchester, Massachusetts);  Jacqueline Starr (Lexington, Massachusetts);  Daniel Ferrer (Boston, Massachusetts)
ABSTRACT Provided herein are methods and compositions related to bacteria of genus Rothia useful as therapeutic agents for dental caries.
FILED Thursday, January 13, 2022
APPL NO 17/575160
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 6/00 (20130101)
A61K 35/747 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872261 Remaley et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Alan T. Remaley (Bethesda, Maryland);  Scott M. Gordon (Lexington, Kentucky)
ABSTRACT Described herein is the design and construction of a class of lipoprotein targeting protease inhibitors. Small peptides with protease inhibitor activity are conjugated to hydrophobic, lipoprotein targeting molecules using, for instance, amine reactive chemistry. Methods of use of the resultant lipoprotein targeting protease inhibitor (antiprotease) molecules are also described. Also described is the production and use of protease inhibitor enriched HDL particles, as well as A1AT-peptide-enriched HDL particles, and their use in various therapeutic contexts.
FILED Wednesday, February 16, 2022
APPL NO 17/673361
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/005 (20130101) Original (OR) Class
A61K 38/07 (20130101)
A61K 38/08 (20130101)
A61K 38/10 (20130101)
A61K 38/58 (20130101)
A61K 38/1767 (20130101)
A61K 47/60 (20170801)
A61K 47/545 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872277 He et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Linling He (San Diego, California);  Jiang Zhu (San Diego, California);  Anshul Chaudhary (La Jolla, California);  Ian Wilson (La Jolla, California)
ABSTRACT The present invention provides novel engineered Ebolavirus GP proteins and polypeptides, scaffolded vaccine compositions that display the engineered proteins, and polynucleotides encoding the engineered proteins and scaffolded vaccine compositions. The invention also provides methods of using such engineered Ebolavirus GP proteins and vaccine compositions in various therapeutic applications, e.g., for preventing or treating Ebolavirus infections.
FILED Thursday, April 07, 2022
APPL NO 17/715658
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class

Peptides
C07K 14/473 (20130101)
C07K 2317/34 (20130101)
C07K 2319/735 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/14134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872286 Quijano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Elias Quijano (Durham, Connecticut);  Peter Glazer (Guilford, Connecticut)
ABSTRACT Compositions and methods of use thereof for delivering nucleic acid cargo into cells are provided. The compositions typically include (a) a 3E10 monoclonal antibody or an antigen binding, cell-penetrating fragment thereof; a monovalent, divalent, or multivalent single chain variable fragment (scFv); or a diabody; or humanized form or variant thereof, and (b) a nucleic acid cargo including, for example, a nucleic acid encoding a polypeptide, a functional nucleic acid, a nucleic acid encoding a functional nucleic acid, or a combination thereof. Elements (a) and (b) are typically non-covalently linked to form a complex.
FILED Tuesday, August 30, 2022
APPL NO 17/823488
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/549 (20170801) Original (OR) Class
A61K 47/6807 (20170801)
A61K 47/6851 (20170801)
A61K 48/00 (20130101)
A61K 48/005 (20130101)
A61K 48/0025 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/52 (20130101)
C07K 14/4747 (20130101)
C07K 16/44 (20130101)
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/77 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/87 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 15/1135 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2310/3181 (20130101)
C12N 2310/3513 (20130101)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872311 Lin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Wenbin Lin (Chicago, Illinois);  Demin Liu (Round Lake, Illinois);  Joseph Della Rocca (Blue Bell, Pennsylvania);  Stephanie Kramer (Johnson City, Tennessee);  Christopher Y. Poon (Carlsbad, California)
ABSTRACT Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents.
FILED Tuesday, February 25, 2020
APPL NO 16/800855
ART UNIT RD00 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/14 (20130101)
A61K 9/0019 (20130101)
A61K 9/127 (20130101) Original (OR) Class
A61K 9/5115 (20130101)
A61K 9/5123 (20130101)
A61K 9/5146 (20130101)
A61K 31/663 (20130101)
A61K 31/675 (20130101)
A61K 47/548 (20170801)
A61K 47/6925 (20170801)
A61K 47/6929 (20170801)
A61K 49/00 (20130101)
A61K 51/1244 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/08 (20180101)
A61P 19/10 (20180101)
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872312 Huang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Board of Regents of The University of Texas System (Austin, Texas)
ASSIGNEE(S) THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMS (Austin, Texas)
INVENTOR(S) Shao-Ling Huang (Houston, Texas);  Melvin E. Klegerman (Houston, Texas);  Yong-Jian Geng (Houston, Texas);  Hyunggun Kim (Houston, Texas);  David D. McPherson (Houston, Texas)
ABSTRACT Methods for the treatment of stroke, such as stroke of undetermined origin, by administration of xenon (Xe)-loaded liposome compositions are provided. In some aspects, Xe is encapsulated in echogenic liposomes and release of Xe can be enhanced by application of ultrasound stimulation. Compositions for use in treating stroke, such as liposomes loaded with Xe or Xe in combination with H2 or H2S, are also provided.
FILED Tuesday, April 13, 2021
APPL NO 17/229627
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/127 (20130101) Original (OR) Class
A61K 33/00 (20130101)
A61K 41/0028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872313 Lanza et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S)
INVENTOR(S) Gregory M. Lanza (St. Louis, Missouri);  Dipanjan Pan (St. Louis, Missouri)
ABSTRACT The present invention encompasses prodrug compositions, nanoparticles comprising one or more prodrugs, and methods of use thereof.
FILED Thursday, November 05, 2020
APPL NO 17/090574
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/08 (20130101)
A61K 9/10 (20130101)
A61K 9/0019 (20130101)
A61K 9/145 (20130101) Original (OR) Class
A61K 9/1075 (20130101)
A61K 9/1271 (20130101)
A61K 31/336 (20130101)
A61K 31/337 (20130101)
A61K 33/24 (20130101)
A61K 33/242 (20190101)
A61K 33/243 (20190101)
A61K 41/0071 (20130101)
A61K 47/555 (20170801)
A61K 47/6907 (20170801)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/773 (20130101)
Y10S 977/906 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872318 Popov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Alexey Popov (Waltham, Massachusetts);  Elizabeth M. Enlow (Waltham, Massachusetts);  James Bourassa (Somerville, Massachusetts);  Colin R. Gardner (Concord, Massachusetts);  Hongming Chen (Belmont, Massachusetts);  Laura M. Ensign (Towson, Maryland);  Samuel K. Lai (Carrboro, North Carolina);  Tao Yu (Baltimore, Maryland);  Justin Hanes (Baltimore, Maryland);  Ming Yang (Towson, Maryland)
ABSTRACT Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP) without any polymeric carriers, or with minimal use of polymeric carriers. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles formed of pharmaceutical agents that have a low water solubility. Such methods and compositions can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier.
FILED Monday, January 23, 2023
APPL NO 18/100363
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/10 (20130101)
A61K 9/5031 (20130101) Original (OR) Class
A61K 9/5089 (20130101)
A61K 9/5138 (20130101)
A61K 31/12 (20130101)
A61K 31/56 (20130101)
A61K 31/58 (20130101)
A61K 31/341 (20130101)
A61K 31/405 (20130101)
A61K 31/409 (20130101)
A61K 31/496 (20130101)
A61K 31/522 (20130101)
A61K 31/569 (20130101)
A61K 31/573 (20130101)
A61K 31/635 (20130101)
A61K 31/662 (20130101)
A61K 31/675 (20130101)
A61K 47/34 (20130101)
A61K 49/0089 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872385 Smith
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
ASSIGNEE(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
INVENTOR(S) William Smith (Cleveland, Ohio)
ABSTRACT A blood pump (10) includes a pump housing (30) having a pump inlet (16) and a pump outlet (18) spaced apart along a longitudinally extending central pump axis (28). The blood pump (10) also includes a rotating assembly (100) comprising an impeller (104). The blood pump (10) further includes partial arc journal bearings (160, 180) that support the rotating assembly (100) for rotation in the housing (30). The rotating assembly (100) is rotatable relative to the housing (30) to pump blood from the pump inlet (16) to the pump outlet (18).
FILED Wednesday, March 13, 2019
APPL NO 16/980795
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 60/82 (20210101) Original (OR) Class
A61M 60/148 (20210101)
A61M 60/178 (20210101)
A61M 60/237 (20210101)
A61M 60/422 (20210101)
A61M 60/812 (20210101)
A61M 60/824 (20210101)
A61M 60/825 (20210101)
A61M 2205/103 (20130101)
A61M 2210/125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872394 Bhadra et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERAITY (Cleveland, Ohio);  NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT (Bethesda, Maryland)
INVENTOR(S) Niloy Bhadra (Cleveland Heights, Ohio);  Narendra Bhadra (Chesterland, Ohio);  Kevin L Kilgore (Avon Lake, Ohio);  Scott Lempka (Cleveland Heights, Ohio);  Jesse Wainright (Willoughby Hills, Ohio);  Tina Vrabec (Willoughby Hills, Ohio);  Manfred Franke (Redwood City, California)
ABSTRACT Described herein are systems and methods for the treatment of pain using electrical nerve conduction block (ENCB). Contrary to other methods of pain treatment, the ENCB can establish a direct block of neural activity, thereby eliminating the pain. Additionally, the ENCB can be administered without causing electrochemical damage. An example method can include: placing at least one electrode contact in electrical communication with a region of a subject's spinal cord; applying an electrical nerve conduction block (ENCB) to a nerve in the region through the at least one electrode contact; and blocking neural activity with the ENCB to reduce the pain or other unwanted sensation in the subject.
FILED Thursday, May 13, 2021
APPL NO 17/319180
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/06 (20130101)
A61N 1/20 (20130101)
A61N 1/205 (20130101)
A61N 1/0456 (20130101)
A61N 1/0551 (20130101) Original (OR) Class
A61N 1/0556 (20130101)
A61N 1/3615 (20130101)
A61N 1/36017 (20130101)
A61N 1/36021 (20130101)
A61N 1/36062 (20170801)
A61N 1/36071 (20130101)
A61N 1/36125 (20130101)
A61N 1/36171 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872398 Noble et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) Jack H. Noble (Nashville, Tennessee);  Robert F. Labadie (Nashville, Tennessee);  Benoit M. Dawant (Nashville, Tennessee)
ABSTRACT A method for designing a patient-customized EA or selecting an existing EA that fits the patient best includes segmenting shapes of SOIs of the cochlea in a pre-operative CT image using a shape model; defining a 3D curve of interest within the shape model of the SOIs as a sequence of points-; automatically transforming the defined 3D curve to the pre-operative CT image so as to obtain a structure curve in the cochlea; determining a length and curvatures of the structure curve at the sequence of points; and designing a patient-customized EA or selecting an existing EA based on the determined length and curvatures of the structure curve such that after the EA shape model, which estimates the resting state shape of the EA, is rigidly registered to the structure curve in the cochlea, the EA shape model has a registration error smaller than a preset value.
FILED Monday, June 07, 2021
APPL NO 17/340303
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101)
A61B 5/1076 (20130101)
A61B 6/032 (20130101)
A61B 34/10 (20160201)
A61B 2034/105 (20160201)
A61B 2034/107 (20160201)
A61B 2034/108 (20160201)
A61B 2505/05 (20130101)
A61B 2562/043 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0541 (20130101)
A61N 1/36039 (20170801) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/12 (20170101)
G06T 7/181 (20170101)
G06T 11/005 (20130101)
G06T 2207/30008 (20130101)
G06T 2211/424 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872554 Schenk zu Schweinsberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) ABBOTT DIAGNOSTICS SCARBOROUGH, INC. (Scarborough, Maine)
ASSIGNEE(S) ABBOTT DIAGNOSTICS SCARBOROUGH, INC. (Scarborough, Maine)
INVENTOR(S) Alexander Schenk zu Schweinsberg (Jena, Germany);  Austin Matthew Derfus (Solana Beach, California);  Justin Davidson (San Diego, California);  Karthikeyan Kumaravadivelu (San Diego, California);  Maulik Vinod Patel (La Crescenta, California);  Olaf Piepenburg (Saffron Walden, United Kingdom);  Catherine Jean Greenwood (Sawbridgeworth, United Kingdom);  Oliver Nentwich (Cambridge, United Kingdom)
ABSTRACT A microfluidic device includes an inlet port configured to receive a sample, a first reaction chamber fluidically coupled to the inlet port, a first pump fluidically coupled to the inlet port, a second pump fluidically coupled to a mixing chamber, a metering channel fluidically coupled to the first reaction chamber and to the mixing chamber, and one or more second reaction chambers fluidically coupled to the mixing chamber. The first pump is configured to move fluid from the inlet port to the first reaction chamber and from the first pump to the inlet port. The second pump is configured to move fluid from the second pump to the mixing chamber, from the first reaction chamber to the mixing chamber, and from the mixing chamber to the one or more second reaction chambers.
FILED Monday, March 09, 2020
APPL NO 16/812961
ART UNIT 1799 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5029 (20130101)
B01L 3/502715 (20130101) Original (OR) Class
B01L 2200/027 (20130101)
B01L 2200/082 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/0478 (20130101)
B01L 2400/0655 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/14 (20130101)
G01N 1/38 (20130101)
G01N 35/00069 (20130101)
G01N 2001/028 (20130101)
G01N 2035/00158 (20130101)
G01N 2035/1034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873266 Pelletier et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Aeromics, Inc. (New Haven, Connecticut)
ASSIGNEE(S) AEROMICS, INC. (New Haven, Connecticut)
INVENTOR(S) Marc F. Pelletier (Shaker Heights, Ohio);  George William Farr (Rocky River, Ohio);  Paul Robert McGuirk (Spring Hill, Florida);  Christopher H Hall (Shaker Heights, Ohio);  Walter F. Boron (Shaker Heights, Ohio)
ABSTRACT The present invention relates to the use of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the prophylaxis, treatment and control of aquaporin-mediated conditions, e.g., diseases of water imbalance, for example edema (particularly edema of the brain and spinal cord, e.g., following trauma or ischemic stroke, as well as the edema associated with glioma, meningitis, acute mountain sickness, epileptic seizures, infections, metabolic disorders, hypoxia, water intoxication, hepatic failure, hepatic encephalopathy, diabetic ketoacidosis, abscess, eclampsia, Creutzfeldt-Jakob disease, and lupus cerebritis, as well as edema consequent to microgravity and/or radiation exposure, as well as edema consequent to invasive central nervous system procedures, e.g., neurosurgery, endovascular clot removal, spinal tap, aneurysm repair, or deep brain stimulation, as well as retinal edema), as well as hyponatremia and excess fluid retention, and diseases such as epilepsy, retinal ischemia and other diseases of the eye associated with abnormalities in intraocular pressure and/or tissue hydration, myocardial ischemia, myocardial ischemia/reperfusion injury, myocardial infarction, myocardial hypoxia, congestive heart failure, sepsis, and neuromyelitis optica, as well as migraines, as well as to novel assays for identifying aquaporin inhibitors.
FILED Monday, July 26, 2021
APPL NO 17/443361
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/24 (20130101)
A61K 31/167 (20130101)
A61K 31/661 (20130101)
A61K 31/5375 (20130101)
A61K 31/6615 (20130101)

Acyclic or Carbocyclic Compounds
C07C 235/64 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 295/185 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873288 Hammock et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Bruce Hammock (Davis, California);  Sean Kodani (Orangevale, California)
ABSTRACT The present invention provides compounds that are dual inhibitors of soluble epoxide hydrolase and fatty acid amide hydrolase. The present invention also provides methods of using the compounds to inhibit soluble epoxide hydrolase and fatty acid amide hydrolase, and to treat cancer.
FILED Friday, December 04, 2020
APPL NO 17/112713
ART UNIT RD00 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 275/28 (20130101)
C07C 275/34 (20130101)
C07C 275/36 (20130101)
C07C 2601/14 (20170501)

Heterocyclic Compounds
C07D 211/16 (20130101)
C07D 211/46 (20130101)
C07D 271/10 (20130101)
C07D 401/06 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 401/14 (20130101)
C07D 413/14 (20130101)
C07D 417/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873312 Eberwine et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) James Eberwine (Philadelphia, Pennsylvania);  Ivan J. Dmochowski (Philadelphia, Pennsylvania);  Sean B. Yeldell (Philadelphia, Pennsylvania);  Julianne C. Griepenburg (Philadelphia, Pennsylvania);  Teresa L. Rapp (Philadelphia, Pennsylvania);  Jennifer M. Singh (Havertown, Pennsylvania);  Jai-Yoon Sul (Cherry Hill, New Jersey);  Jaehee Lee (Wynnewood, Pennsylvania)
ABSTRACT Compositions and methods of capturing one or more nucleic acid molecules of a cell or subcellular compartment are described. In certain aspects, the compositions comprise a caged molecule comprising one or more photolinkers and an antisense oligonucleotide, which when uncaged hybridizes to a target nucleic acid molecule.
FILED Friday, May 28, 2021
APPL NO 17/333376
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 35/004 (20130101)
B01J 2531/821 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 15/0053 (20130101) Original (OR) Class

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 23/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 13/00 (20130101)
C12N 15/113 (20130101)
C12N 2310/11 (20130101)
C12N 2310/32 (20130101)
C12N 2310/351 (20130101)
C12N 2310/531 (20130101)
C12N 2310/3233 (20130101)
C12N 2310/3517 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6818 (20130101)
C12Q 1/6823 (20130101)
C12Q 1/6825 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873319 Vance et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
NIH Office of the Director (NIHOD)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Russell E. Vance (Albany, California);  Ming C. Hammond (Berkeley, California);  Dara Burdette (Berkeley, California);  Elie J. Diner (San Rafael, California);  Stephen C. Wilson (Berkeley, California)
ABSTRACT Methods and compositions are provided for increasing the production of a type I interferon (IFN) in a cell. Aspects of the methods include increasing the level of a 2′-5′ phosphodiester linkage comprising cyclic-di-nucleotide in a cell in a manner sufficient to increase production of the type I interferon (IFN) by the cell. Also provided are compositions and kits for practicing the embodiments of the methods.
FILED Wednesday, September 01, 2021
APPL NO 17/464494
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7084 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873374 Gao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ruixuan Gao (Cambridge, Massachusetts);  Linyi Gao (Cambridge, Massachusetts);  Chih-Chieh Yu (Cambridge, Massachusetts);  Edward Stuart Boyden (Chestnut Hill, Massachusetts)
ABSTRACT The invention encompasses hydrogels, monomer precursors of the hydrogels, methods for the preparation thereof, and methods of use therefor. The linking of monomers can take place using non-radical, bioorthogonal reactions such as copper-free click-chemistry.
FILED Tuesday, February 05, 2019
APPL NO 16/267849
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 8/00 (20130101)
C08F 8/00 (20130101)
C08F 8/00 (20130101)
C08F 8/04 (20130101)
C08F 8/04 (20130101)
C08F 8/12 (20130101)
C08F 8/12 (20130101)
C08F 8/12 (20130101)
C08F 8/30 (20130101)
C08F 8/30 (20130101)
C08F 8/30 (20130101)
C08F 8/30 (20130101)
C08F 8/30 (20130101)
C08F 8/44 (20130101)
C08F 8/44 (20130101)
C08F 8/44 (20130101)
C08F 20/18 (20130101)
C08F 20/18 (20130101)
C08F 20/18 (20130101)
C08F 20/18 (20130101)
C08F 220/04 (20130101)
C08F 220/303 (20200201)
C08F 220/346 (20200201)
C08F 222/104 (20200201)
C08F 2438/01 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 65/32 (20130101)
C08G 65/2624 (20130101)
C08G 81/025 (20130101)
C08G 2210/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/075 (20130101) Original (OR) Class
C08J 3/246 (20130101)
C08J 2300/206 (20130101)
C08J 2400/206 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6834 (20130101)
C12Q 1/6841 (20130101)
C12Q 1/6869 (20130101)
C12Q 1/6869 (20130101)
C12Q 2521/107 (20130101)
C12Q 2523/101 (20130101)
C12Q 2525/191 (20130101)
C12Q 2527/125 (20130101)
C12Q 2543/101 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/30 (20130101)
G01N 1/36 (20130101)
G01N 15/0205 (20130101)
G01N 33/545 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873477 Yu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Marshall University Research Corporation (Huntington, West Virginia)
ASSIGNEE(S) MARSHALL UNIVERSITY RESEARCH CORPORATION (Huntington, West Virginia)
INVENTOR(S) Hongwei D. Yu (Huntington, West Virginia);  Meagan E. Valentine (Huntington, West Virginia);  Richard M. Niles (Huntington, West Virginia);  Thomas Ryan Withers (Huntington, West Virginia);  Brandon D. Kirby (Huntington, West Virginia)
ABSTRACT Bacterial cultures are provided that comprise a modified Pseudomonas aeruginosa bacterium missing or deficient in two or more virulence factors. The two or more virulence factors can be selected from exotoxin A, hemolytic phospholipase C, phenazine-specific methyltransferase, alpha-1,3-rhamnosyltransferase, and 3-phosphoshikimate 1-carboxyvinyltransferase. Certain of the modified Pseudomonas aeruginosa bacteria are also missing or deficient in one or more alginate acetylation enzymes including the alginate Oacetyltransferases AlgI, AlgJ, AlgF, AlgX, and/or the C5-mannuronan epimerase AlgG. Methods of producing alginate are also provided along with compositions comprising alginate produced by the modified Pseudomonas aeruginosa bacteria.
FILED Thursday, March 14, 2019
APPL NO 16/980198
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Compositions of Macromolecular Compounds
C08L 5/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)
C12N 1/205 (20210501) Original (OR) Class

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/38 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873479 Scharenberg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington)
ASSIGNEE(S) SEATTLE CHILDREN'S RESEARCH INSTITUTE (Seattle, Washington)
INVENTOR(S) Andrew M. Scharenberg (Seattle, Washington);  Michael T. Certo (Seattle, Washington);  Kamila Sabina Gwiazda (Seattle, Washington)
ABSTRACT The present disclosure relates to the co-expression of an endonuclease with an end-processing enzyme for the purpose of enhanced processing of the polynucleotide ends generated by endonuclease cleavage.
FILED Thursday, April 29, 2021
APPL NO 17/244190
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 35/28 (20130101)
A61K 38/45 (20130101)
A61K 38/45 (20130101)
A61K 38/52 (20130101)
A61K 38/52 (20130101)
A61K 38/465 (20130101)
A61K 38/465 (20130101)
A61K 2035/124 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 2319/60 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/90 (20130101)
C12N 9/1252 (20130101)
C12N 15/62 (20130101)
C12N 15/102 (20130101) Original (OR) Class
C12N 2800/80 (20130101)
C12N 2840/203 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873486 Meyerson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Matthew Meyerson (Concord, Massachusetts);  William N. Haining (Newton, Massachusetts);  Jeffrey Ishizuka (Boston, Massachusetts);  Robert Manguso (Boston, Massachusetts);  Hugh Gannon (Groton, Massachusetts)
ABSTRACT The present invention relates, in part, to methods of treating a subject afflicted with a cancer comprising administering to the subject a therapeutically effective amount of an agent that inhibits or promotes the copy number, the expression level, and/or the activity of one or more biomarkers listed in Table 1 or a fragment thereof. Also provided herein are methods of detecting ADAR1 or ISG15 dependency in a high proliferation cell (e.g., a cancer cell). Also provided are methods of detected increased interferon signaling pathway activity in a high proliferation cell (e.g., a cancer cell). Included herein are methods of treating cancer with inhibitors of ADAR1 or ISG15. Methods of screening for such inhibitors are also provided herein. Methods of identifying the likelihood of a cancer to be responsive to an ADAR1 inhibitor are also provided.
FILED Monday, April 02, 2018
APPL NO 16/497294
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/712 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/111 (20130101) Original (OR) Class
C12N 2310/14 (20130101)
C12N 2310/531 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873487 Mello et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Craig Mello (Barrington, Rhode Island);  Krishna Sumanth Ghanta (Grafton, Massachusetts)
ABSTRACT The disclosure provides novel methods and compositions for gene editing. In particular, the disclosure relates to compositions and methods of making nucleic acid donor templates for highly efficient and precise gene editing.
FILED Monday, August 08, 2022
APPL NO 17/818226
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/01 (20130101)
C12N 15/111 (20130101) Original (OR) Class
C12N 15/902 (20130101)
C12N 2310/20 (20170501)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873496 Young et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) Richard A. Young (Boston, Massachusetts);  Abraham S. Weintraub (Somerville, Massachusetts);  Charles H. Li (Waban, Massachusetts);  Alla A. Sigova (Newton, Massachusetts)
ABSTRACT The invention relates to methods of modulating the expression of one or more genes in a cell by modulating the multimerization of a transcription factor and/or modulating the formation of enhancer-promoter DNA loops, and thereby modulating the expression of the one or more genes. The invention also relates to treating diseases and conditions involving aberrant gene expression by modulating the multimerization of a transcription factor and/or modulating the formation of enhancer-promoter DNA loops. The invention also relates to methods for screening for compounds that modulate expression of one or more genes in a cell.
FILED Tuesday, January 09, 2018
APPL NO 16/476868
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/4702 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/67 (20130101) Original (OR) Class
C12N 15/85 (20130101)
C12N 15/113 (20130101)
C12N 2015/859 (20130101)
C12N 2310/51 (20130101)
C12N 2310/53 (20130101)
C12N 2830/001 (20130101)
C12N 2830/15 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873510 Prabhakar
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Bellur Prabhakar (Oak Brook, Illinois)
ABSTRACT This invention relates to methods of expanding T regulatory cells through OX40L and Jagged-1 induced signaling. The methods can be used for treating autoimmune diseases.
FILED Thursday, May 21, 2020
APPL NO 16/879923
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 35/17 (20130101)
A61K 35/28 (20130101)
A61K 35/28 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/02 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0637 (20130101) Original (OR) Class
C12N 2501/22 (20130101)
C12N 2501/415 (20130101)
C12N 2501/998 (20130101)
C12N 2501/999 (20130101)
C12N 2502/08 (20130101)
C12N 2502/1121 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873518 Romney et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) David K. Romney (Pasadena, California);  Javier Murciano Calles (Ubeda Jaen, Spain);  Jori E. Wehrmuller (Hohenrain, Switzerland)
ABSTRACT This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids.
FILED Tuesday, April 19, 2022
APPL NO 17/724390
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Heterocyclic Compounds
C07D 209/20 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/88 (20130101) Original (OR) Class

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 13/227 (20130101)

Enzymes
C12Y 402/0102 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874276 Barbie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) David Barbie (Andover, Massachusetts);  Israel Cañadas (Brookline, Massachusetts);  Shunsuke Kitajima (Allston, Massachusetts);  Thanh Barbie (Andover, Massachusetts)
ABSTRACT Provided herein are Stimulator of Interferon Genes (STING) and Stimulated 3 Prime Antisense Retroviral Coding Sequences (SPARCS) genes as biomarkers for determining an effective therapy for treating cancer. Further provided are methods for treating cancer using said biomarkers.
FILED Friday, April 05, 2019
APPL NO 17/045148
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/005 (20130101)
A61K 38/21 (20130101)
A61K 38/217 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/57 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6866 (20130101)
G01N 33/57423 (20130101)
G01N 33/57484 (20130101) Original (OR) Class
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874283 Newman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institutes of Health Clinical Center (NIHCC)
APPLICANT(S) MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia)
ASSIGNEE(S) Morehouse School of Medicine (Atlanta, Georgia)
INVENTOR(S) Gale W. Newman (Duluth, Georgia);  James W. Lillard, Jr. (Smyrna, Georgia);  Chamberlain Obialo (Atlanta, Georgia)
ABSTRACT The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.
FILED Thursday, April 29, 2021
APPL NO 17/244214
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/40 (20130101)
A61K 31/422 (20130101)
A61K 31/505 (20130101)
A61K 31/506 (20130101)
A61K 31/4025 (20130101)
A61K 38/12 (20130101)
A61K 45/06 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/74 (20130101)
G01N 33/78 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 33/56988 (20130101)
G01N 2333/5754 (20130101)
G01N 2800/28 (20130101)
G01N 2800/52 (20130101)
G01N 2800/347 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874353 Berman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts);  Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Avery J. L. Berman (Jamaica Plain, Massachusetts);  Jonathan R. Polimeni (Cambridge, Massachusetts);  William A. Grissom (Nashville, Tennessee);  Kawin Setsompop (Charlestown, Massachusetts);  Thomas Witzel (Boston, Massachusetts)
ABSTRACT Described here are systems and methods for producing images with a magnetic resonance imaging (“MRI”) system using a high-resolution, motion-robust, artifact-free segmented echo planar imaging (“EPI”) technique. In particular, a fast low angle excitation echo planar imaging technique (“FLEET”) using variable flip angle (“VFA”) radio frequency (“RF”) excitation pulses that are recursively designed to have a flat magnitude and phase profile across a slice for a range of different flip angles by accounting for longitudinal magnetization remaining after each preceding RF pulse is applied.
FILED Friday, March 27, 2020
APPL NO 17/598035
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4818 (20130101)
G01R 33/4835 (20130101) Original (OR) Class
G01R 33/5608 (20130101)
G01R 33/5616 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874358 Tamada et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Daiki Tamada (Madison, Wisconsin);  Scott B. Reeder (Middleton, Wisconsin)
ABSTRACT A system and method are provided for controlling a magnetic resonance imaging (MRI) system. The method includes performing a gradient echo pulse sequence that includes a phase increment of an RF pulse of the gradient echo pulse sequence selected to encode diffusion information into a phase of MR signals. The method also includes controlling the plurality of gradient coils and the RF system to acquire the MR signals as MR data, processing the MR data to determine MR signals corresponding to diffusion in the subject when acquiring the MR signals, and generating at least one of an image or a map of the subject indicating the diffusion in the subject from the MR data.
FILED Tuesday, March 15, 2022
APPL NO 17/695409
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5608 (20130101)
G01R 33/5615 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874359 Tian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Qiyuan Tian (Charlestown, Massachusetts);  Susie Yi Huang (Boston, Massachusetts);  Berkin Bilgic (Boston, Massachusetts)
ABSTRACT Higher quality diffusion metrics and/or diffusion-weighted images are generated from lower quality input diffusion-weighted images using a suitably trained neural network (or other machine learning algorithm). High-fidelity scalar and orientational diffusion metrics can be extracted using a theoretical minimum of a single non-diffusion-weighted image and six diffusion-weighted images, achieved with data-driven supervised deep learning. As an example, a deep convolutional neural network (“CNN”) is used to map the input non-diffusion-weighted image and diffusion-weighted images sampled along six optimized diffusion-encoding directions to the residuals between the input and output high-quality non-diffusion-weighted image and diffusion-weighted images, which enables residual learning to boost the performance of CNN and full tensor fitting to generate any scalar and orientational diffusion metrics.
FILED Friday, March 27, 2020
APPL NO 17/442817
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5608 (20130101)
G01R 33/56341 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/045 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874451 Huang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Bo Huang (San Francisco, California);  Bin Yang (San Francisco, California)
ABSTRACT In one embodiment, a microscopy system includes a first objective positioned adjacent to a sample to be imaged, the first objective being configured to both illuminate the sample with light and collect light from the sample, and a remote imaging module positioned remotely from the first objective and the sample, the remote imaging module being configured to rotate the image plane of the collected light.
FILED Thursday, January 31, 2019
APPL NO 16/966829
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/02 (20130101)
G02B 21/06 (20130101)
G02B 21/16 (20130101)
G02B 21/18 (20130101)
G02B 21/33 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875509 Griswold et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) Case Western Reserve University (Cleveland, Ohio)
INVENTOR(S) Mark A. Griswold (Shaker Heights, Ohio);  Dan Ma (Solon, Ohio);  Debra McGivney (Bay Village, Ohio);  Rasim Boyacioglu (Cleveland Heights, Ohio)
ABSTRACT A method for determining an undersampling error for a magnetic resonance fingerprinting (MRF) pulse sequence includes retrieving a plurality of sets of spatial response functions. Each set of spatial response functions is associated with a tissue type in a reference image and is based on a tissue mask of the reference image for each tissue type. A signal evolution for each tissue type may be generated based on, for example, the MRF pulse sequence, An undersampled image may be generated for each tissue type using the set of spatial response functions and the signal evolutions for the tissue type. At least one quantitative parameter may be determined by comparing an undersampled image series created from the undersampled images to an MRF dictionary. An undersampling error for the MRF pulse sequence may be generated by comparing a quantitative map (or maps) for the quantitative parameter (or parameters) and the reference image.
FILED Monday, April 05, 2021
APPL NO 17/301492
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/50 (20130101)
G01R 33/445 (20130101)
G01R 33/4625 (20130101)
G01R 33/4824 (20130101)
G01R 33/5608 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0014 (20130101) Original (OR) Class
G06T 2207/10088 (20130101)
G06T 2207/30016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875702 Tatum et al.
FUNDED BY
Department of Health and Human Services (HHS)
Agency for Healthcare Research and Quality (AHRQ)
APPLICANT(S) University of lowa Research Foundation (Iowa City, Iowa)
ASSIGNEE(S) UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
INVENTOR(S) Marcus Tatum (Iowa City, Iowa);  Geb W. Thomas (Iowa City, Iowa)
ABSTRACT A system for simulating surgery includes an electromagnetic tracking system comprising an emitter and a plurality of electromagnetic sensors and a plurality of model bone fragments, each of the model bone fragments operatively connected to one of the plurality of electromagnetic sensors. A method for simulating surgery includes electromagnetically tracking position of a plurality of model bone fragments and a model bone shaft using an electromagnetic tracking system and displaying virtual fluoroscopic images based on sensed position of the model bone fragments and the model bone shaft.
FILED Friday, June 24, 2022
APPL NO 17/848810
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/0206 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 9/00 (20130101)
G09B 23/30 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875813 Mesgarani et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Nima Mesgarani (New York, New York);  Enea Ceolini (New York, New York);  Cong Han (New York, New York)
ABSTRACT Disclosed are methods, systems, device, and other implementations, including a method (performed by, for example, a hearing aid device) that includes obtaining a combined sound signal for signals combined from multiple sound sources in an area in which a person is located, and obtaining neural signals for the person, with the neural signals being indicative of one or more target sound sources, from the multiple sound sources, the person is attentive to. The method further includes determining a separation filter based, at least in part, on the neural signals obtained for the person, and applying the separation filter to a representation of the combined sound signal to derive a resultant separated signal representation associated with sound from the one or more target sound sources the person is attentive to.
FILED Friday, March 31, 2023
APPL NO 18/129469
ART UNIT 2659 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 21/028 (20130101) Original (OR) Class
G10L 21/0232 (20130101)
G10L 2021/02087 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875876 Lu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy Kuan-Ta Lu (Cambridge, Massachusetts);  Manolis Kellis (Boston, Massachusetts);  Jicong Cao (Cambridge, Massachusetts);  Eva Maria Novoa Pardo (Cambridge, Massachusetts);  Zhizhuo Zhang (Cambridge, Massachusetts)
ABSTRACT Disclosed herein are novel 5′ UTR sequences that can be used to control gene expression in various contexts. Also disclosed herein are methods of engineering 5′ UTR sequences and methods and kits for screening 5′ UTR sequences for a property of interest.
FILED Friday, June 14, 2019
APPL NO 16/441647
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 15/85 (20130101)
C12N 15/1089 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/50 (20190201) Original (OR) Class
G16B 40/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875983 Ouyang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Zheng Ouyang (West Lafayette, Indiana);  Yue Ren (West Lafayette, India);  Ziqing Lin (West Lafayette, Indiana)
ABSTRACT The invention generally relates to systems and methods for quantifying an analyte extracted from a sample. In certain embodiments, the invention provides methods that involve introducing a solvent into a capillary, introducing the capillary into a vessel including a sample such that a portion of the sample is introduced into the capillary, moving the sample and the solvent within the capillary to induce circulation within the sample and the solvent, thereby causing the analyte to be extracted from the sample and into the solvent, analyzing the analyte that has been extracted from the sample, and quantifying the analyte. In certain embodiments, the quantifying step is performed without knowledge of a volume of the sample and/or solvent.
FILED Thursday, November 03, 2022
APPL NO 17/979972
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/167 (20130101) Original (OR) Class

Technical Subjects Covered by Former US Classification
Y10T 436/24 (20150115)
Y10T 436/255 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11871975 Brown et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Wake Forest University Health Sciences (Winston-Salem, North Carolina)
ASSIGNEE(S) Wake Forest University Health Sciences (Winston-Salem, North Carolina)
INVENTOR(S) Philip J. Brown (Winston-Salem, North Carolina);  Andrea Morgan Rich (Winston-Salem, North Carolina);  Aaron Ross Van Gorkom (Winston-Salem, North Carolina)
ABSTRACT Disclosed herein are surgical tool systems and methods of using such to install a fixator in a biological tissue. The systems are capable of accurately measuring torque and rotational velocity and providing real time feedback to a user during surgery.
FILED Thursday, October 05, 2017
APPL NO 16/339400
ART UNIT 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/1626 (20130101)
A61B 17/8875 (20130101) Original (OR) Class
A61B 2560/0462 (20130101)
A61B 2560/0475 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872022 Franceschini et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Maria Angela Franceschini (Charlestown, Massachusetts);  Stefan Carp (Boston, Massachusetts);  Davide Tamborini (Charlestown, Massachusetts);  David Boas (Charlestown, Massachusetts);  Bruce Rosen (Charlestown, Massachusetts);  Megan Blackwell (Charlestown, Massachusetts);  Oleg Shatrovoy (Charlestown, Massachusetts)
ABSTRACT An apparatus, including: a probe to interface with a surface of a tissue; a light source optically coupled to the probe, the light source directing light of at least 1000 nm into the tissue; a detector optically coupled to the probe, the detector to detect light based on scattering of light from the light source in the tissue, and the detector having a light sensitivity in a range of at least 1000 nm; a processor coupled to the detector, the processor to: receive a signal from the detector corresponding to the detected light from the light source, and determine a blood flow measurement from the region of interest using diffuse correlation spectroscopy based on the signal.
FILED Monday, February 18, 2019
APPL NO 16/970670
ART UNIT 2878 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0261 (20130101) Original (OR) Class
A61B 2562/0233 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/44 (20130101)
G01J 2001/448 (20130101)
G01J 2001/4453 (20130101)
G01J 2001/4466 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/107 (20130101)
H01L 31/109 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872084 Barnes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Ronald A Barnes (San Antonio, Texas);  Hope T Beier (San Antonio, Texas);  Bennett L Ibey (San Antonio, Texas);  Caleb Roth (San Antonio, Texas)
ABSTRACT An acoustic imaging system responsive to an acoustic wave emitted from an object is disclosed. The system detects a deflection angle of an electromagnetic probe beam as it passes through a coupling element. The coupling element also couples the acoustic wave emitted from the object to an acoustic detector. The probe beam deflection angle is related to an angle of propagation of the acoustic wave through the coupling element. A filtering unit is configured to remove components of the signal from the acoustic detector that are outside of a range of angles, thereby improving the angular resolution of the acoustic detector. The acoustic wave may be generated by an acoustic source, such as an ultrasound transmitter, or an electromagnetic source such as a laser.
FILED Monday, August 22, 2022
APPL NO 17/821303
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/54 (20130101)
A61B 8/5223 (20130101) Original (OR) Class
A61B 8/5269 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872371 Zanos et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York)
ASSIGNEE(S) THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (Manhasset, New York)
INVENTOR(S) Theodoros Zanos (Astoria, New York);  Todd Levy (Kew Gardens, New York);  Emily Battinelli (Franklin Square, New York);  Kevin J. Tracey (Old Greenwich, Connecticut);  Chad E. Bouton (Darien, Connecticut);  Sangeeta Chavan (Syosset, New York);  Harold Silverman (Plainview, New York)
ABSTRACT The present disclosure relates to systems, methods and devices to monitor, diagnose and/or treat diseases or disorders comprising a calibration phase and a real-time diagnostic, treatment or monitoring phase, the calibration phase correlating a plurality of nerve activity measurements from a chronically implanted electrode in a subject with a plurality of concurrent measurements of levels of cytokines and/or glucose in the blood to obtain a functional relationship between blood cytokine and/or glucose levels and vagus nerve activity, and the diagnostic, treatment or monitoring phase analyzing the subject's real-time vagus nerve activity in accordance with the previously obtained functional relationship to initiate a treatment method.
FILED Thursday, April 19, 2018
APPL NO 16/605818
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/388 (20210101)
A61B 5/7225 (20130101)
A61B 5/7264 (20130101)
A61B 5/7282 (20130101)
A61B 5/14532 (20130101)
A61B 5/14546 (20130101)
A61B 2560/0214 (20130101)
A61B 2560/0238 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/1723 (20130101) Original (OR) Class

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36053 (20130101)
A61N 1/36139 (20130101)
A61N 7/00 (20130101)
A61N 2007/0026 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872418 McFaddin
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Donald A McFaddin (Williams, Indiana)
ABSTRACT Provided is a Fall Arrest Staple that includes a slanted base with a flat welding surface and an integral ring section extending from the base that is constructed from aluminum with a maximum internal radii that is capable of accepting a small carabineer. The staple can be welded to an aluminum pole, such as a 4″OD×0.25″ mast that is found on a ship. Advantages provided by the staple include the ability of welding in a perpendicular orientation to a ship deck (in the direction of a fall), welding to a curved aluminum backing plate, and the use of the staple with a curved backing plate that can be welded directly to a ship mast.
FILED Thursday, June 30, 2022
APPL NO 17/854502
ART UNIT 3631 — Static Structures, Supports and Furniture
CURRENT CPC
Devices, Apparatus or Methods for Life-saving
A62B 35/0068 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872562 Riley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
APPLICANT(S) U.S. Army Combat Capabilities Development Command, Chemical Biological Center (APG, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Patrick C Riley (Bel Air, Maryland);  Brian C Hauck (Baltimore, Maryland)
ABSTRACT A sealable sampling container includes a vessel having a bottom and walls upwardly extending therefrom and terminating in a sealing surface, the bottom and the walls defining a volume within the open top container. A gasket is configured to engage with the sealing surface of the vessel and a lid is configured to engage with the gasket at the sealing surface and lock to the vessel. A sampling port is affixed to one side of the vessel or the lid, the sampling port providing fluid communication between the volume within the open top container and an external environment. The sealable sampling container safely stores volatile chemical vapors and enables training on use of chemical detection equipment without resort to ventilation hoods or the use of respiratory protection equipment.
FILED Monday, March 29, 2021
APPL NO 17/216295
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/508 (20130101) Original (OR) Class
B01L 2300/041 (20130101)
B01L 2300/0858 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/22 (20130101)
G01N 33/0004 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 19/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872628 Sherman et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Powdermet, Inc. (Euclid, Ohio)
ASSIGNEE(S) Powdermet, Inc. (Euclid, Ohio)
INVENTOR(S) Andrew J. Sherman (Mentor, Ohio);  Brian Werry (Euclid, Ohio)
ABSTRACT A structured three-phase composite which include a metal phase, a ceramic phase, and a gas phase that are arranged to create a composite having low thermal conductivity, having controlled stiffness, and a CTE to reduce thermal stresses in the composite when exposed to cyclic thermal loads. The structured three-phase composite is useful for use in structures such as, but not limited to, heat shields, cryotanks, high speed engine ducts, exhaust-impinged structures, and high speed and reentry aeroshells.
FILED Thursday, August 23, 2018
APPL NO 16/110600
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal
B21D 3/00 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/04 (20130101)
B22F 3/16 (20130101)
B22F 3/1007 (20130101)
B22F 3/1007 (20130101)
B22F 3/1112 (20130101) Original (OR) Class
B22F 2003/1106 (20130101)
B22F 2201/20 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/16 (20130101)
B32B 5/18 (20130101)
B32B 5/20 (20130101)

Alloys
C22C 1/1084 (20130101)
C22C 1/1084 (20130101)
C22C 32/0031 (20130101)
C22C 32/0036 (20130101)
C22C 32/0078 (20130101)
C22C 49/00 (20130101)
C22C 49/06 (20130101)
C22C 49/11 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872631 Parsons
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ethan Parsons (Cambridge, Massachusetts)
ABSTRACT Compositions and methods of making compositions for additive manufacturing of composite powders including metal ceramic alloyed material is described.
FILED Friday, November 05, 2021
APPL NO 17/520134
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/05 (20220101)
B22F 9/04 (20130101) Original (OR) Class
B22F 10/28 (20210101)
B22F 2009/041 (20130101)
B22F 2301/052 (20130101)
B22F 2304/10 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 40/10 (20200101)
B33Y 70/10 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873081 Covington et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) Bell Textron Inc. (Fort Worth, Texas)
ASSIGNEE(S) Textron Innovations Inc. (Providence, Rhode Island)
INVENTOR(S) Charles Eric Covington (Colleyville, Texas);  Chia-Wei Su (Lewisville, Texas);  Darren Gregory Lang (Dallas, Texas);  Thomas Parsons (Fort Worth, Texas);  Cody Earl Fegely (Irving, Texas)
ABSTRACT A rotorcraft has a drive system including a main rotor coupled to a main rotor gearbox to rotate the main rotor at a rotor speed, a main engine coupled to the drive system to provide a first power, a supplemental engine coupled, when a first clutch is engaged, to the drive system to provide a second power additive to the first power, and a control system operable to control the main engine and the supplemental engine to provide a total power demand, where the main engine is controlled based on variations in rotor speed and a power compensation command to produce the first power, and the supplemental engine is controlled to produce the second power in response to a supplemental power demand.
FILED Wednesday, June 09, 2021
APPL NO 17/342963
ART UNIT 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/12 (20130101) Original (OR) Class

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 31/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873096 Spring et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Cornerstone Research Group, Inc. (Miamisburg, Ohio)
ASSIGNEE(S) Cornerstone Research Group, Inc. (Miamisburg, Ohio)
INVENTOR(S) S. Alan Spring (Dayton, Ohio);  Cory Kays (Beavercreek, Ohio);  Joshua Nieman (Centerville, Ohio);  Bryan Pelley (Sugarcreek Township, Ohio)
ABSTRACT An aircraft wing and propulsion system includes a leading-edge device positioned at the leading edge of an aircraft wing and one or more propulsors affixed to the main body of the aircraft wing. The leading-edge device includes a moveable slat affixed to the aircraft wing with an extension mechanism such that the moveable slat is translatable between a closed position abutting a main body of the aircraft wing and an open position extended from the main body of the aircraft wing to form a gap. An associated method of operating the same during takeoff and landing includes extending the moveable slat to expose the propulsors on the aircraft wing and operating the propulsors during take-off or landing of the aircraft to provide increased power and lift for the aircraft.
FILED Wednesday, February 09, 2022
APPL NO 17/667648
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 9/24 (20130101) Original (OR) Class
B64C 11/02 (20130101)
B64C 11/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873119 Duron et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Space and Missile Defense Command (SMDC)
APPLICANT(S) U.S. Army Space and Missile Defense Command (Huntsville, Alabama)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Christopher M. Duron (New Market, Alabama);  Gauge C. Day (Cullman, Alabama);  Jessica L. Shrontz (Madison, Alabama);  Travis S. Taylor (Somerville, Alabama)
ABSTRACT A modular satellite chassis includes frame rails having at least two front frame rails and two back frame rails. Transverse parallel ribs are disposed on the interiors of the front and back frame rails. The ribs on the front frame rails correspond in location to one another and to the ribs on the back frame rails. Each rib has a central longitudinal axis and a narrow first slot disposed along the central longitudinal axis. The ribs are spaced apart by wider second slots. Trays are slidingly received by the second slots on the front frame rails and the corresponding second slots on the back frame rails. A left side panel is connected to an outside of one of the front frame rails and one of the back frame rails. A right side panel is connected to an outside of the other front frame rail and the other back frame rail.
FILED Wednesday, July 17, 2019
APPL NO 16/514242
ART UNIT 2841 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/10 (20130101) Original (OR) Class
B64G 1/223 (20230801)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/1434 (20130101)
H05K 7/1439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873123 Shockley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Liberty M. Shockley (Albuquerque, New Mexico);  Robert A. Bettinger (Oakwood, Ohio)
ABSTRACT The present invention relates to an aerospace vehicle navigation and control system comprising a terrestrial illumination matching module for determining spacecraft position and attitude. The method permits aerospace vehicle position and attitude determinations using terrestrial lights using an Earth-pointing camera without the need of a dedicated sensor to track stars, the sun, or the horizon. Thus, a module for making such determinations can easily and inexpensively be made onboard an aerospace vehicle if an Earth-pointing sensor, such as a camera, is present.
FILED Wednesday, December 16, 2020
APPL NO 17/123810
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/242 (20130101)
B64G 1/244 (20190501)
B64G 1/245 (20230801)
B64G 3/00 (20130101) Original (OR) Class

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/24 (20130101)

Image Data Processing or Generation, in General
G06T 7/74 (20170101)
G06T 7/277 (20170101)
G06T 2207/30181 (20130101)
G06T 2207/30244 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873340 Dekaban et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) The University of Western Ontario (London, Canada);  ELI LILLY AND COMPANY (Indianapolis, Indiana)
ASSIGNEE(S) The University of Western Ontario (London, Canada);  Eli Lilly and Company (Indianapolis, Indiana)
INVENTOR(S) Gregory Dekaban (London, Canada);  Arthur Brown (London, Canada);  Lynne Weaver (London, Canada);  Allan Barrett (Indianapolis, Indiana);  Kristine Kikly (Indianapolis, Indiana)
ABSTRACT Antibodies to human CD11d, compositions comprising such CD11d antibodies, and methods of using such CD11d antibodies for the treatment of central nervous system trauma including spinal cord injury and traumatic brain injury, as well as systemic inflammatory response following central nervous system trauma.
FILED Friday, February 24, 2017
APPL NO 16/078813
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)
A61P 37/06 (20180101)

Peptides
C07K 16/2845 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873396 Macfarlane et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Robert J. Macfarlane (Cambridge, Massachusetts);  Jianyuan Zhang (Cambridge, Massachusetts);  Peter Jeffries Santos (Cambridge, Massachusetts);  Paul Anthony Gabrys (Cambridge, Massachusetts)
ABSTRACT Nanostructures and associated compositions, systems, and methods are provided. In some embodiments, a nanostructure may comprise polymers, intermolecular bonding groups, and a particle. The polymers may be associated with the particle and the intermolecular bonding groups may be associated with at least some of the polymers. In some embodiments, at least some of the intermolecular bonding groups may have a different chemical composition and/or chemical property than the polymers. In some embodiments, nanostructures may reversibly associate with each other via the intermolecular bonding groups to form a material. In some such cases, the intermolecular bonding groups on different nanostructures may reversibly associate with each other. In some embodiments, the nanostructures may be designed, such that the energy required to disassociate at least a portion of the nanostructures in the material is greater than the energy required to dissociate a single association between intermolecular bonding groups.
FILED Thursday, August 05, 2021
APPL NO 17/394964
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 40/00 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 2438/00 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/16 (20130101)
C08K 3/22 (20130101)

Compositions of Macromolecular Compounds
C08L 51/00 (20130101)
C08L 51/10 (20130101) Original (OR) Class
C08L 2207/53 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873485 Hochrein et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Lisa Hochrein (Chicago, Illinois);  Mikhail H. Hanewich-Hollatz (Pasadena, California);  Zhewei Chen (Pasadena, California);  Heyun Li (Pasadena, California);  Shashank Gandhi (Pasadena, California);  Marianne Bronner (Pasadena, California);  Niles A. Pierce (South Pasadena, California)
ABSTRACT Programmable guide RNAs (gRNAs) play a central role in the CRISPR revolution sweeping biology and medicine by directing the function of a Cas protein effector to a target gene of choice. To achieve programmable control over regulatory scope, the activity of a conditional guide RNA (cgRNA) depends on the presence or absence of an RNA trigger, allowing for cell-selective regulation of CRISPR/Cas function. Unlike a standard gRNA, a cgRNA is programmable at multiple levels, with the target-binding sequence controlling the target of Cas activity (edit, silence, induce, or bind a gene of choice) and the trigger binding sequence controlling the scope of Cas activity. cgRNA mechanisms that are allosteric allow for independent design of the target and trigger sequences, providing the flexibility to select the regulatory target and scope independently. Disclosed herein are allosteric cgRNA mechanisms for both ON→OFF logic (conditional inactivation by an RNA trigger) and OFF→ON logic (conditional activation by an RNA trigger). Allosteric cgRNAs enable restriction of CRISPR/Cas function to a desired cell type, tissue, organ, or disease state. Allosteric cgRNAs provide a versatile platform for cell-selective and tissue-selective research tools, biotechnologies, diagnostics, and therapeutics.
FILED Tuesday, January 25, 2022
APPL NO 17/584237
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101) Original (OR) Class
C12N 2310/15 (20130101)
C12N 2310/20 (20170501)
C12N 2310/344 (20130101)
C12N 2310/531 (20130101)
C12N 2310/532 (20130101)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873735 Boyer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Mitchell Harold Boyer (Cincinnati, Ohio);  Christopher Timothy Roll (West Chester, Ohio);  Kristin Lynn Bolte Baxter (Mason, Ohio);  Joseph Saeler (Batavia, Ohio)
ABSTRACT A composite component for a gas turbine engine includes a body including a composite material. Furthermore, the composite component includes a connection feature integrally woven to the body. Additionally, the connection portion includes a composite material. Moreover, the composite material of the body and the composite material of the connection feature include alternating layers of fiber tows integrally woven together.
FILED Thursday, November 10, 2022
APPL NO 17/984545
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/30 (20130101)
F01D 5/282 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2300/6034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873788 Son et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Steven Forrest Son (West Lafayette, Indiana);  Kyle Uhlenhake (Lafayette, Indiana);  Diane Collard (West Lafayette, Indiana);  Mateo Gomez (West Lafayette, Indiana)
ABSTRACT An igniter system and method for igniting a propellant by an optical energy source. The igniter system including an igniter composite and a propellant. The igniter composite including a reactive component and a fluoropolymer. The propellant is coupled to the igniter composite. The igniter composite has a composition including nano-aluminum at ideal stoichiometry in polyvinylidene fluoride. The igniter composite is configured to achieve a sustained ignition from a wavelength emitted from the optical energy source. The wavelength is between around 250 nanometers to around 1100 nanometers.
FILED Monday, February 28, 2022
APPL NO 17/682026
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Jet-propulsion Plants
F02K 9/95 (20130101)

Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines
F02P 23/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874279 Walt et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) David R. Walt (Boston, Massachusetts);  David M. Rissin (Lexington, Massachusetts)
ABSTRACT Arrays of single molecules and methods of producing an array of single molecules are described. Arrays with defined volumes between 10 attoliters and 50 picoliters enable single molecule detection and quantitation.
FILED Friday, October 08, 2021
APPL NO 17/496926
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6837 (20130101)
C12Q 1/6837 (20130101)
C12Q 2527/143 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/543 (20130101)
G01N 33/581 (20130101) Original (OR) Class
G01N 33/54346 (20130101)
G01N 33/54366 (20130101)
G01N 33/54386 (20130101)
G01N 2333/938 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874375 Crouch et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) BLACKMORE SENSORS and ANALYTICS, LLC (Palo Alto, California)
ASSIGNEE(S) BLACKMORE SENSORS and ANALYTICS, LLC. (Palo Alto, California)
INVENTOR(S) Stephen C. Crouch (McFarland, Wisconsin);  Randy R. Reibel (Bozeman, Montana);  James Curry (Bozeman, Montana);  Trenton Berg (Manhattan, Montana)
ABSTRACT Techniques for automatic adaptive scanning with a laser scanner include obtaining range measurements at a coarse angular resolution and forming a horizontally sorted range gate subset and a characteristic range. A fine angular resolution is determined automatically based on the characteristic range and a target spatial resolution. If the fine angular resolution is finer than the coarse angular resolution, then a minimum and maximum vertical angle is automatically determined in each horizontal slice extending a bin size from any previous horizontal slice. A set of adaptive minimum and maximum vertical angles is determined automatically by dilating and interpolating the minimum and maximum vertical angles of all the slices to the second horizontal angular resolution. A horizontal start angle, and the set of adaptive minimum and maximum vertical angles are sent to cause the ranging system to obtain measurements at the second angular resolution.
FILED Thursday, January 27, 2022
APPL NO 17/586523
ART UNIT 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/18 (20130101)
G01S 13/343 (20130101)
G01S 13/428 (20130101)
G01S 13/526 (20130101)
G01S 13/582 (20130101)
G01S 17/42 (20130101) Original (OR) Class
G01S 17/89 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874581 Kolmakov et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Research Foundation of the City University of New York (New York, New York)
ASSIGNEE(S) Research Foundation of the City University of New York (New York, New York)
INVENTOR(S) German V. Kolmakov (Bellerose, New York);  Shaina E. Raklyar (Brooklyn, New York)
ABSTRACT An electro-optical converter that converts an electric signal to an optical signal. An optical signal is dragged from one optical channel to another optical channel using exciton polaritons that are generated in a layer that is adjacent the optical channels. The exciton polaritons are generated in response to an electrical signal which thereby results in the selective production of the optical signal.
FILED Wednesday, June 23, 2021
APPL NO 17/355330
ART UNIT 2896 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3132 (20130101) Original (OR) Class
G02F 2203/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875211 Cox et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) United States of America as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Stephen Cox (San Diego, California);  Raymond Provost (San Diego, California);  Iryna Dzieciuch (San Diego, California)
ABSTRACT Smart sensors apparatus for detecting environmental conditions. The smart sticker apparatus includes a radio frequency identification tag comprising a chip and a loop antenna, the loop antenna being configured to transmit sensor information to an external reader, a plurality of sensors configured to provide environmental data, each of the sensors further comprising a substrate having a proximal side and a distal side, wherein the proximal side of the substrate is mounted to the chip, a conductive ink trace disposed on the distal side of the substrate, and a resin fully enveloping the radio frequency identification tag and partially enveloping the distal side of the substrate.
FILED Friday, June 24, 2022
APPL NO 17/848754
ART UNIT 2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 19/0717 (20130101)
G06K 19/0723 (20130101)
G06K 19/0776 (20130101) Original (OR) Class
G06K 19/07773 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875245 Rodriguez
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Rome, New York)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Rome, New York)
INVENTOR(S) Dilia E. Rodriguez (Fayetteville, New York)
ABSTRACT Systems and associated methods for constructing neural networks (NN) without the benefit of predefined output spike times or predefined network architecture. Functions are constructed from other functions determined from an input construction training set of output variable type. Method aspects of the neural network modeler may comprise partitioning the construction training set, representing the partitions, restricting the representations, constructing subfunctions from the restrictions, and combining the subfunctions to model the target function. Specifically, subfunctions represented from partition-specific neural networks of output value type are created using two fundamental composition operations: same-constant composition and different-constants composition. Different choices of weights and delays lead to different NNs with different output spikes that implement the same function.
FILED Thursday, November 08, 2018
APPL NO 16/184041
ART UNIT 2129 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 18/214 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/045 (20230101)
G06N 3/049 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875272 Kim et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Non-Profit Organization (NPO)
Semiconductor Research Corporation (SRC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Hyung-il Kim (Minneapolis, Minnesota);  Ibrahim Ahmed (Minneapolis, Minnesota);  Po-wei Chiu (Minneapolis, Minnesota)
ABSTRACT Compute engine circuitry configured to represent a spin network mapping of a graph representing a combinatorial optimization problem includes a plurality of ring oscillator cells, each of which includes a ring oscillator having an oscillator output, at least one coupling block, and a read block. Each coupling block connects the ring oscillator of the cell to the ring oscillator of one of a plurality of neighboring cells to form a coupled ring oscillator. The read block generates a state output for each coupled ring oscillator that indicates whether the coupled ring oscillator is in one of a same-phase state, in which the connected ring oscillators oscillate in phase with each other, and an opposite-phase state, in which the connected ring oscillators oscillate in an opposite phase from each other. A controller is configured to output a total energy of the mapping based on the state outputs.
FILED Friday, March 26, 2021
APPL NO 17/213396
ART UNIT 2849 — AI & Simulation/Modeling
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Electric Digital Data Processing
G06F 17/10 (20130101)
G06F 17/11 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/01 (20230101) Original (OR) Class
G06N 5/04 (20130101)
G06N 7/01 (20230101)
G06N 7/08 (20130101)
G06N 10/00 (20190101)

Pulse Technique
H03K 3/0315 (20130101)
H03K 5/19 (20130101)
H03K 19/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875557 Xu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Department of Justice (DOJ)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Felix Juefei Xu (Pittsburgh, Pennsylvania);  Marios Savvides (Pittsburgh, Pennsylvania)
ABSTRACT The invention proposes a method of training a convolutional neural network in which, at each convolution layer, weights for one seed convolutional filter per layer are updated during each training iteration. All other convolutional filters are polynomial transformations of the seed filter, or, alternatively, all response maps are polynomial transformations of the response map generated by the seed filter.
FILED Monday, April 29, 2019
APPL NO 16/976409
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 18/21 (20230101)
G06F 18/253 (20230101)
G06F 18/2414 (20230101)
G06F 18/21355 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/045 (20230101)
G06N 3/048 (20230101)
G06N 3/084 (20130101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101) Original (OR) Class
G06V 10/454 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875704 Dixon et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) US Govt as represented by Secretary of Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Angela R. Dixon (Beavercreek, Ohio);  Saber M. Hussain (Beavercreek, Ohio)
ABSTRACT A nasal simulator includes a three-dimensional (3D) printed nasal cavity within based on diagnostic imagery of a human nasal cavity. The nasal simulator comprising a fan system positioned to mimic air flow through the human nasal cavity. A first probe access bore is formed through the 3D printed nasal cavity to a first location having a first internal contour. An anemometer insert having an outer diameter sized to be slidingly received in and to pneumatically seal the first probe access bore, the anemometer insert having a distal contour that aligns with the first internal contour of the 3D printed nasal cavity, the anemometer insert having a longitudinal bore that is sized to receive a probe of an anemometer to detect characteristics of the air flow through the 3D cavity.
FILED Tuesday, July 21, 2020
APPL NO 16/934357
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 9/52 (20130101)
B01L 2300/0663 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5005 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 5/001 (20130101)
G01P 5/02 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 23/00 (20130101)
G09B 23/30 (20130101)
G09B 23/32 (20130101)
G09B 23/34 (20130101)
G09B 23/288 (20130101)
G09B 23/306 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875876 Lu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Timothy Kuan-Ta Lu (Cambridge, Massachusetts);  Manolis Kellis (Boston, Massachusetts);  Jicong Cao (Cambridge, Massachusetts);  Eva Maria Novoa Pardo (Cambridge, Massachusetts);  Zhizhuo Zhang (Cambridge, Massachusetts)
ABSTRACT Disclosed herein are novel 5′ UTR sequences that can be used to control gene expression in various contexts. Also disclosed herein are methods of engineering 5′ UTR sequences and methods and kits for screening 5′ UTR sequences for a property of interest.
FILED Friday, June 14, 2019
APPL NO 16/441647
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 15/85 (20130101)
C12N 15/1089 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/50 (20190201) Original (OR) Class
G16B 40/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875908 Russo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. DEVCOM Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) John A Russo (Spencerville, Maryland);  Marc S. Litz (Columbia, Maryland);  William B. Ray, II (Lubbock, Texas)
ABSTRACT An electrode for beta-photovoltaic cells includes: a substrate formed of a conductive layer with a thickness ranging between about 10 nm to 1 micron; a composite layer of radioluminescent phosphor with radioisotope particles homogeneously dispersed therein formed on conductive substrate with a thickness ranging between about 1 and 25 microns; and a semiconductor comprising a P-i-N/P-u-N junction or a N-i-P-P junction. The radioisotope may be a beta-emitter, such as Ni-63, H-3, Pm-147, or Sr-90/Y-90.
FILED Wednesday, June 30, 2021
APPL NO 17/363886
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 13/02 (20130101)
C25D 13/22 (20130101)

Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation
G21H 3/02 (20130101) Original (OR) Class

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/055 (20130101)
H01L 31/075 (20130101)
H01L 31/1884 (20130101)
H01L 31/03046 (20130101)
H01L 31/03048 (20130101)
H01L 31/022475 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875964 Rameau et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Physical Sciences, Inc. (Andover, Massachusetts)
ASSIGNEE(S) Physical Sciences, Inc. (Andover, Massachusetts)
INVENTOR(S) Jonathan D. Rameau (Somerville, Massachusetts);  Nicholas R. Craig (Somerville, Massachusetts)
ABSTRACT A triple-point cathode coating and method wherein electrically conductive NEA diamond particles cast or mixed with the adhesive medium and electrically insulative NEA diamond particles are cast or mixed with the adhesive medium to form a plurality of exposed junctions between electrically conductive diamond particles and electrically insulative diamond particles to reduce any electrical charges on a structure coated with the coating.
FILED Friday, July 02, 2021
APPL NO 17/366552
ART UNIT 2896 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/226 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/24 (20130101)
C09D 163/00 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 1/3044 (20130101) Original (OR) Class
H01J 3/022 (20130101)
H01J 9/025 (20130101)
H01J 2201/30411 (20130101)
H01J 2201/30457 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 427/103 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876115 Heller
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Eric Heller (Kettering, Ohio)
ABSTRACT A gallium oxide field effect transistor that is built on a base layer. A doped gallium oxide channel layer is disposed on top of the base layer, and a dielectric barrier layer is disposed on top of the gallium oxide channel layer. Source contacts and drain contacts are disposed on top of the dielectric barrier layer, with one each of the drain contacts disposed in an interdigitated manner between one each of the source contacts. The interdigitated source contacts and drain contacts thereby define channels between them, where alternating ones of the channels are defined as odd channels, with even channels disposed therebetween. Gate contacts are disposed on top of the dielectric barrier layer in only one of the odd channels and the even channels.
FILED Friday, March 04, 2022
APPL NO 17/686546
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/24 (20130101) Original (OR) Class
H01L 29/0696 (20130101)
H01L 29/41758 (20130101)
H01L 29/42356 (20130101)
H01L 29/66969 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876168 Hersam et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Mark C. Hersam (Wilmette, Illinois);  Kan-Sheng Chen (Chicago, Illinois);  Ethan B. Secor (Chicago, Illinois)
ABSTRACT Composites comprising anode and cathode active materials conformally coupled to few-layered graphene, corresponding electrodes and related methods of preparation.
FILED Wednesday, July 07, 2021
APPL NO 17/369058
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/133 (20130101)
H01M 4/134 (20130101)
H01M 4/136 (20130101)
H01M 4/139 (20130101)
H01M 4/0416 (20130101)
H01M 4/505 (20130101)
H01M 4/625 (20130101)
H01M 4/1393 (20130101)
H01M 10/0525 (20130101) Original (OR) Class
H01M 2004/027 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876178 Xu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland);  The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland);  The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Kang Xu (Potomac, Maryland);  Chunsheng Wang (Silver Spring, Maryland);  Chongyin Yang (College Park, Maryland)
ABSTRACT The present invention is directed to aqueous solid state electrolytes that comprise a fluoride additive to stabilize the interface between the anode and aqueous electrolyte. The present invention is also directed to methods of making the solid state electrolyte materials and methods of using the solid state electrolyte materials in batteries and other electrochemical technologies.
FILED Friday, August 24, 2018
APPL NO 16/641895
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/134 (20130101)
H01M 4/386 (20130101)
H01M 4/505 (20130101)
H01M 4/667 (20130101)
H01M 4/5835 (20130101)
H01M 10/0525 (20130101)
H01M 10/0567 (20130101) Original (OR) Class
H01M 2004/021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876337 Dong et al.
FUNDED BY
Department of Defense (DOD)
Joint Directed Energy Transition Office (DE-JTO)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) CLEMSON UNIVERSITY (Clemson, South Carolina)
ASSIGNEE(S) CLEMSON UNIVERSITY (Clemson, South Carolina)
INVENTOR(S) Liang Dong (Clemson, South Carolina);  Turghun Matniyaz (Clemson, South Carolina)
ABSTRACT High-power, highly efficient 3-level system fiber lasers are described. The lasers can operate at an average power of about 50W or greater with an efficiency of about 60% or greater with low diffraction limited mode quality. The lasers incorporate an all-solid photonic bandgap fiber that includes a large core (20 micrometers or greater), a high core/clad ratio (greater than 15%), and a waveguide cladding designed to define a transmission band to suppress the 4-level system of the gain medium through determination of the node size of individual nodes of a cladding lattice.
FILED Monday, September 21, 2020
APPL NO 17/026760
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/175 (20130101)
H01S 3/176 (20130101)
H01S 3/0675 (20130101)
H01S 3/1618 (20130101)
H01S 3/06716 (20130101)
H01S 3/06733 (20130101)
H01S 3/06741 (20130101) Original (OR) Class
H01S 3/09415 (20130101)
H01S 3/094007 (20130101)
H01S 3/094042 (20130101)
H01S 3/094053 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876877 Forero et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Pedro Forero (San Diego, California);  Peng Zhang (San Diego, California);  Dusan Radosevic (San Diego, California)
ABSTRACT A reinforcement-learning based queue-management method for undersea networks. In one embodiment, a computer-implemented method to shape traffic in a dynamic network, comprising measuring network states, classifying each of a plurality of packets into one of a plurality of traffic types based on quality-of-service requirements, defining a decision epoch interval, determining a policy with a plurality of neural networks and with a deep reinforcement learning agent that maximizes entropy-regularized long-term reward and produces a plurality of weighted fair-queuing weights based on an observation of the state of the queues at the decision epoch intervals, and using the policy to allocate predefined portions of the available transmission bandwidth across the plurality of traffic types by defining each type with a WFQ weight.
FILED Monday, March 27, 2023
APPL NO 18/190204
ART UNIT 2452 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 47/22 (20130101)
H04L 67/61 (20220501) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11877504 Dou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Letian Dou (West Lafayette, Indiana);  Blake Peter Finkenauer (West Lafayette, Indiana)
ABSTRACT A perovskite-polymer composite comprising a perovskite and a polymer, wherein the polymer has a structural unit comprising a thiourea (—HN(C═S)NH—) fragment and a (—R1—O—R2—) fragment, wherein R1 and R2 are each independently a C1-C6 alkyl or a cycloalkyl linker; a mechanically robust and self-healable solar cell comprising same; and a method of making same.
FILED Thursday, April 14, 2022
APPL NO 17/720348
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Organic electric solid-state devices
H10K 30/10 (20230201)
H10K 85/10 (20230201) Original (OR) Class
H10K 85/40 (20230201)
H10K 2102/101 (20230201)
H10K 2102/351 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11877517 Jiang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S) North Carolina State University (Raleigh, North Carolina)
INVENTOR(S) Xiaoning Jiang (Raleigh, North Carolina);  Taeyang Kim (Raleigh, North Carolina);  Yong Zhu (Raleigh, North Carolina)
ABSTRACT Disclosed are various embodiments for a piezo-composite transducer that is flexible such that it may conform to regular or irregular shapes. A flexible piezo-composite transducer may include an active piezoelectric material, such as PZT-5H, and a passive polymer matrix formed of a flexible material, such as polydimethylsiloxane (PDMS). The flexible piezo-composite transducer may include a first side and a second side, where each of the first side and the second side include a first electrode and a second electrode deposited thereon, respectively. At least one of the first electrode and the second electrode may include a silver nanowire (AgNW) and PDMS electrode that is flexible.
FILED Wednesday, March 04, 2020
APPL NO 16/808786
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Electric solid-state devices not otherwise provided for
H10N 30/092 (20230201)
H10N 30/302 (20230201)
H10N 30/852 (20230201) Original (OR) Class
H10N 30/877 (20230201)
H10N 30/8554 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11872543 Debusk et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Melanie M. Debusk (Oak Ridge, Tennessee);  Sreshtha Sinha Majumdar (Oak Ridge, Tennessee);  Josh A. Pihl (Oak Ridge, Tennessee)
ABSTRACT A method of manufacturing a methane oxidation catalyst and methane oxidation catalysts formed by the method are provided. The method includes providing a palladium (Pd)-based catalyst including Pd dispersed onto a support. A magnesium (Mg) precursor is introduced to the Pd-based catalyst by one of ion exchange or incipient wetness impregnation. After introducing the magnesium precursor to the Pd-based catalyst, the catalyst is dried and subjected to a final heat treatment that includes hydrothermal calcination. A method of methane oxidation in a lean exhaust environment via the methane oxidation catalyst is also provided.
FILED Monday, May 09, 2022
APPL NO 17/739263
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 21/10 (20130101)
B01J 23/44 (20130101) Original (OR) Class
B01J 29/7015 (20130101)
B01J 35/04 (20130101)
B01J 35/1014 (20130101)
B01J 37/08 (20130101)
B01J 37/0207 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 39/48 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2006/12 (20130101)
C01P 2006/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872749 LaPlant et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) HONEYWELL FEDERAL MANUFACTURING and TECHNOLOGIES, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Steven Todd LaPlant (Kansas City, Missouri);  Michael Joseph Batrick (Kansas City, Missouri);  Ruben Arturo Pino (Kansas City, Missouri)
ABSTRACT A system and method of additively manufacturing a part via salt micro-spheres. The method includes mixing salt micro-spheres with an additive manufacturing material to form an additive manufacturing material mixture. The additive manufacturing material mixture is deposited on a build platform layer by layer and cured so as to create a structure having pores formed by the salt micro-spheres. The salt micro-spheres may then be dissolved and flushed from the pores.
FILED Friday, April 29, 2022
APPL NO 17/732821
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/35 (20170801)
B29C 64/165 (20170801) Original (OR) Class
B29C 64/205 (20170801)
B29C 64/245 (20170801)
B29C 64/314 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2105/041 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 40/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872772 Sinha et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Sanjiv Sinha (Champaign, Illinois);  Placid M. Ferreira (Champaign, Illinois);  Nenad Miljkovic (Urbana, Illinois);  Manjunath C. Rajagopal (Champaign, Illinois);  Gowtham Kuntumalla (McKinney, Texas);  Akhilesh Sanjay Somani (McKinney, Texas)
ABSTRACT An apparatus for fabricating a hybrid tube includes a rotatable mandrel and a first housing configured to translate alongside the rotatable mandrel while dispensing a first strip to be helically wound about the mandrel. The first housing includes an angle adjustment mechanism to control a dispensation angle of the first strip. The apparatus also includes least one energy or adhesive source for bonding overlapping strip portions on the rotatable mandrel and forming the hybrid tube. The at least one energy or adhesive source is configured for translation alongside the rotatable mandrel.
FILED Monday, July 19, 2021
APPL NO 17/379056
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/32 (20130101) Original (OR) Class

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2023/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873227 Cussler et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Edward Cussler (Minneapolis, Minnesota);  Alon McCormick (Minneapolis, Minnesota);  Michael Reese (Minneapolis, Minnesota);  Deepak Ojha (Minneapolis, Minnesota);  Matt Kale (Minneapolis, Minnesota);  Paul Dauenhauer (Minneapolis, Minnesota);  Prodromos Daoutidis (Minneapolis, Minnesota);  Mohammadmahdi Malmali (Minneapolis, Minnesota)
ABSTRACT Embodiments of the disclosure provide an apparatus and process for producing ammonia. The apparatus includes a reactor having (i) an inlet to receive an inlet gas comprising nitrogen and hydrogen, (ii) a catalyst and an absorbent disposed within an internal volume of the reactor, the catalyst configured to convert the nitrogen and hydrogen to a reaction mixture including ammonia, unreacted nitrogen, and unreacted hydrogen, the absorbent configured to selectively absorb a portion of the ammonia in the reactor during formation of the reaction mixture, and (iii) an outlet to discharge the reaction mixture from the reactor.
FILED Wednesday, April 15, 2020
APPL NO 16/849550
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 8/008 (20130101)
B01J 20/046 (20130101)
B01J 23/745 (20130101)

Ammonia; Cyanogen; Compounds Thereof
C01C 1/0411 (20130101)
C01C 1/0417 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873301 Redline et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Erica M. Redline (Albuquerque, New Mexico);  Chad L. Staiger (Albuquerque, New Mexico);  David R. Wheeler (Albuquerque, New Mexico);  Leah N. Appelhans (Tijeras, New Mexico);  Jeffrey C. Foster (Albuquerque, New Mexico)
ABSTRACT Curatives and their resulting thermosets and other crosslinked polymers can reduce thermal expansion mismatch between an encapsulant and objects that are encapsulated. This can be accomplished by incorporating a negative CTE moiety into the thermoset resin or polymer backbone. The negative CTE moiety can be a thermal contractile unit that shrinks as a result of thermally induced conversion from a twist-boat to chair or cis/trans isomerization upon heating. Beyond CTE matching, other potential uses for these crosslinked polymers and thermosets include passive energy generation, energy absorption at high strain rates, mechanophores, actuators, and piezoelectric applications.
FILED Monday, March 20, 2023
APPL NO 18/123665
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 13/547 (20130101)
C07C 211/60 (20130101)
C07C 2602/12 (20170501)
C07C 2603/30 (20170501)
C07C 2603/36 (20170501)

Heterocyclic Compounds
C07D 321/12 (20130101)
C07D 471/14 (20130101) Original (OR) Class

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/17 (20130101)
C08K 5/053 (20130101)
C08K 5/235 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873367 Jones et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Brad Howard Jones (Albuquerque, New Mexico);  Chad Lynn Staiger (Albuquerque, New Mexico)
ABSTRACT Novel polymers are depolymerizable by metathesis of a cleavable unit. As an example, a series of linear and crosslinked polyurethanes were prepared that can be selectively depolymerized under mild conditions. Two unique polyols were synthesized bearing unsaturated units in a configuration designed to favor ring-closing metathesis to five- and six-membered cycloalkenes. These polyols were co-polymerized with toluene diisocyanate to generate linear polyurethanes and trifunctional hexamethylene- and diphenylmethane-based isocyanates to generate crosslinked polyurethanes. The polyol design is such that the ring-closing metathesis reaction cleaves the backbone of the polymer chain. Upon exposure to dilute solutions of Grubbs' catalyst under ambient conditions, the polyurethanes were rapidly depolymerized to low molecular weight, soluble products bearing vinyl and cycloalkene functionalities. These functionalities enabled further re-polymerization by traditional strategies for polymerization of double bonds. This general approach can be expanded to develop a range of chemically recyclable condensation polymers that are readily depolymerized by orthogonal metathesis chemistry.
FILED Thursday, April 29, 2021
APPL NO 17/244012
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 6/04 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 18/675 (20130101)
C08G 18/725 (20130101)
C08G 18/3206 (20130101) Original (OR) Class
C08G 18/3212 (20130101)
C08G 18/7621 (20130101)
C08G 18/7664 (20130101)
C08G 18/7831 (20130101)
C08G 2110/0008 (20210101)
C08G 2110/0025 (20210101)
C08G 2110/0083 (20210101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 11/10 (20130101)
C08J 11/18 (20130101)
C08J 11/28 (20130101)
C08J 2375/14 (20130101)
C08J 2375/16 (20130101)

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/62 (20150501)
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US 11873382 Kumar et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Vipin Kumar (Oak Ridge, Tennessee);  Ahmed A. Hassen (Oak Ridge, Tennessee);  Christopher J. Hershey (Oak Ridge, Tennessee);  Seokpum Kim (Oak Ridge, Tennessee);  Vlastimil Kunc (Oak Ridge, Tennessee);  John M. Lindahl (Oak Ridge, Tennessee)
ABSTRACT The current embodiments include all-polymeric protective material for mitigating lightning strike damage. The protective material includes a hybrid matrix comprising PANI and MXene dispersed within a thermosetting epoxy resin. This hybrid matrix can be painted, printed, or applied as a conductive polymeric layer to a FRCP structure, for example an aircraft fuselage, wing, empennage, control surface (aileron, flap, slats, rudder, elevator) or a wind turbine blade. The protective material not only withstands lightning strikes, but also functions as shielding against electromagnetic interference and is corrosion-resistant and lightweight.
FILED Wednesday, March 30, 2022
APPL NO 17/708210
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 45/02 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/042 (20130101)
C08J 7/044 (20200101)
C08J 7/0427 (20200101)
C08J 2300/24 (20130101)
C08J 2400/12 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/14 (20130101) Original (OR) Class
C08K 3/041 (20170501)
C08K 2201/001 (20130101)

Wind Motors
F03D 80/30 (20160501)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/06 (20130101)
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US 11873498 Loque et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Dominique Loque (Geneva, Switzerland);  Aymerick Eudes (Emeryville, California)
ABSTRACT The present invention provides an expression cassette comprising a polynucleotide that encodes a protein that diverts a monolignol precursor from a lignin biosynthesis pathway in the plant, which is operably linked to a heterologous promoter. Also provided are methods of engineering a plant having reduced lignin content, as well as plant cells, plant parts, and plant tissues from such engineered plants.
FILED Monday, January 25, 2021
APPL NO 17/157942
ART UNIT 1663 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/88 (20130101)
C12N 15/8255 (20130101) Original (OR) Class

Enzymes
C12Y 402/01118 (20130101)
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US 11873504 Doudna et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A Doudna (Berkeley, California);  Jillian F. Banfield (Berkeley, California);  David Burstein (Berkeley, California);  Lucas Benjamin Harrington (Berkeley, California);  Steven C. Strutt (Berkeley, California)
ABSTRACT The present disclosure provides CasX proteins, nucleic acids encoding the CasX proteins, and modified host cells comprising the CasX proteins and/or nucleic acids encoding same. CasX proteins are useful in a variety of applications, which are provided. The present disclosure provides CasX guide RNAs that bind to and provide sequence specificity to the CasX proteins, nucleic acids encoding the CasX guide RNAs, and modified host cells comprising the CasX guide RNAs and/or nucleic acids encoding same. CasX guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides archaeal Cas9 polypeptides and nucleic acids encoding same, as well as their associated archaeal Cas9 guide RNAs and nucleic acids encoding same.
FILED Thursday, September 28, 2017
APPL NO 16/335516
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 19/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/06 (20130101)
C07K 2319/09 (20130101)
C07K 2319/20 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/1007 (20130101)
C12N 9/1025 (20130101)
C12N 15/52 (20130101)
C12N 15/62 (20130101)
C12N 15/74 (20130101)
C12N 15/85 (20130101)
C12N 15/86 (20130101)
C12N 15/88 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101)
C12N 15/902 (20130101)
C12N 15/8509 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2740/13043 (20130101)
C12N 2740/16043 (20130101)
C12N 2750/14143 (20130101)
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US 11873523 Deng et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Shuang Deng (Richland, Washington);  Jon K. Magnuson (Richland, Washington);  Joonhoon Kim (Berkeley, California);  Kyle R. Pomraning (Richland, Washington);  Ziyu Dai (Richland, Washington);  Beth A. Hofstad (Richland, Washington)
ABSTRACT Recombinant Aspergillus genetically modified to increase expression of g8846, renamed herein as aconitic acid exporter (aexA), are provided, which in some examples are also genetically inactivated for an endogenous cis-aconitic acid decarboxylase (cadA) gene. Such recombinant Aspergillus produce more aconitic acid as compared to native Aspergillus. Also provided are methods of using such recombinant Aspergillus to increase production of aconitic acid and other organic acids, such as citric acid, itaconic acid, and 3-hydroxypropionic acid (3-HP).
FILED Monday, June 14, 2021
APPL NO 17/347109
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/145 (20210501)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/46 (20130101) Original (OR) Class

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/69 (20210501)
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US 11873740 Buscheck et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Thomas A. Buscheck (Pleasanton, California);  Ravindra Shrikrishna Upadhye (Pleasanton, California)
ABSTRACT The present disclosure relates to a system for storing and time shifting at least one of excess electrical power from an electrical power grid, excess electrical power from the power plant itself, or heat from a heat generating source, in the form of pressure and heat, for future use in assisting with a production of electricity. An oxy-combustion furnace is powered by a combustible fuel source, plus excess electricity, during a charge operation to heat a reservoir system containing a quantity of a thermal storage medium. During a discharge operation, a discharge subsystem has a heat exchanger which receives heated CO2 from the reservoir system and uses this to heat a quantity of high-pressure, supercritical CO2 (sCO2) to form very-high-temperature, high-pressure sCO2 at a first output thereof. The very-high-temperature, high-pressure sCO2 is used to drive a Brayton-cycle turbine, which generates electricity at a first output thereof for transmission to a power grid. The Brayton-cycle turbine also outputs a quantity of sCO2 which is reduced in temperature and pressure to a heat recuperator subsystem. The heat recuperator subsystem circulates the sCO2 and re-heats and re-pressurizes the sCO2 before feeding it back to the heat exchanger to be even further reheated, and then output to the Brayton-cycle turbine as a new quantity of very-high-temperature, high-pressure sCO2, to assist in powering the Brayton-cycle turbine.
FILED Monday, August 09, 2021
APPL NO 17/397515
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles
F01K 25/103 (20130101) Original (OR) Class
F01K 27/00 (20130101)

Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 7/04 (20130101)
F03G 7/06 (20130101)

Geothermal Collectors; Geothermal Systems
F24T 10/20 (20180501)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 20/00 (20130101)
F28D 20/0052 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 6/34 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 20/16 (20130101)
Y02E 60/14 (20130101)
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US 11874176 Zhao et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Xiayun Zhao (Pittsburgh, Pennsylvania);  Chaitanya Krishna Prasad Vallabh (Pittsburgh, Pennsylvania)
ABSTRACT A two-wavelength, single-camera imaging thermography system for in-situ temperature measurement of a target, comprising: a target light path inlet conduit for receiving a target light beam reflected from the target; a beam splitter installed in a splitter housing at a distal end of the target light path conduit, wherein the beam splitter divides the target light beam into a first light beam and a second light beam; a first light path conduit emanating from the splitter housing comprising a first aperture iris installed within the first light path conduit for aligning the first light beam; a first band pass filter installed within the first light path conduit for regulating the first light beam to a first wavelength λ1 and an optional half waveplate installed within the first light path conduit to modulate a polarization ratio of the first light beam of λ1 wavelength; a second light path conduit emanating from the splitter housing comprising a second aperture iris installed within the second light path conduit for aligning the second light beam; a second band pass filter installed within the second light path conduit for regulating the second light beam to a second wavelength λ2; a junction housing, wherein distal ends of each of the first and second light path conduits are connected to the junction housing; a polarizing beam splitter installed in the junction housing, wherein the polarizing beam splitter reflects the first light beam of λ1 wavelength along the same path or a parallel path of the second light beam of λ2 wavelength that passes directly through the polarizing beam splitter unreflected to create a merged light beam comprising light of λ1 and λ2 wavelengths; and a light path outlet conduit connected to the junction for directing the merged beam to a high-speed camera for imaging.
FILED Tuesday, September 08, 2020
APPL NO 17/015062
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/48 (20130101)
G01J 5/59 (20220101) Original (OR) Class
G01J 5/0802 (20220101)
G01J 5/0804 (20220101)
G01J 2005/0077 (20130101)

Optical Elements, Systems, or Apparatus
G02B 27/283 (20130101)
G02B 27/286 (20130101)
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US 11874239 Sun et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Chengjun Sun (Naperville, Illinois);  Mikhail A. Solovyev (Western Springs, Illinois);  Steve Heald (Downers Grove, Illinois);  Xiaoyi Zhang (Naperville, Illinois);  Maria Chan (Chicago, Illinois);  Shelly D. Kelly (Bolingbrook, Illinois)
ABSTRACT Spectroscopy systems require a crystal having specific properties for analyzing a spectrum of a sample, which is typically performed for measuring the presence of one element at a time. A two-dimensional (2D) crystal mount for performing simultaneous spectroscopy measurements includes a crystal holder having multiple rows of crystal mounts. Each crystal mount is positioned and orientated to physically support a crystal at a fixed position and fixed orientation relative to an optical axis. A sample provides radiation to analyzer crystals disposed in the crystal mounts, and a detector may detect radiation reflected from the analyzer crystals, for performing multiple simultaneous spectroscopy measurements.
FILED Friday, March 11, 2022
APPL NO 17/692994
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/223 (20130101)
G01N 23/2076 (20130101) Original (OR) Class
G01N 23/2209 (20180201)
G01N 23/20008 (20130101)
G01N 2223/30 (20130101)
G01N 2223/50 (20130101)
G01N 2223/076 (20130101)
G01N 2223/0568 (20130101)
G01N 2223/1016 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874742 Hukerikar et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) NVIDIA CORPORATION (Santa Clara, California)
ASSIGNEE(S) NVIDIA CORPORATION (Santa Clara, California)
INVENTOR(S) Saurabh Hukerikar (Santa Clara, California);  Nirmal Raj Saxena (Los Altos Hills, California)
ABSTRACT In various embodiments, a software program uses hardware features of a parallel processor to checkpoint a context associated with an execution of a software application on the parallel processor. The software program uses a preemption feature of the parallel processor to cause the parallel processor to stop executing instructions in accordance with the context. The software program then causes the parallel processor to collect state data associated with the context. After generating a checkpoint based on the state data, the software program causes the parallel processor to resume executing instructions in accordance with the context.
FILED Thursday, April 22, 2021
APPL NO 17/237376
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 9/3861 (20130101)
G06F 9/30101 (20130101)
G06F 11/0772 (20130101)
G06F 11/1407 (20130101) Original (OR) Class
G06F 11/1438 (20130101)
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US 11874930 Rieger et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Craig G. Rieger (Pocatello, Idaho);  Timothy R. McJunkin (Idaho Falls, Idaho)
ABSTRACT An anomaly detector is configured to construct cyber and/or physical features comprising information configured to characterize the cyber and/or physical state of a cyber-physical system. The physical features may be based on physical and/or physics-based relationships between a plurality of physical state attributes. A health of the cyber-physical system may be based on an error between estimates of one or more of the physical state attributes and measurements of the one or more physical state attributes. The relationships may be incorporated into machine learning membership functions used to classify cyber and/or physical behavior of the system.
FILED Monday, September 21, 2020
APPL NO 17/027463
ART UNIT 2496 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/0754 (20130101)
G06F 11/3466 (20130101)
G06F 21/71 (20130101)
G06F 21/577 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875499 Grodsky et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Rachel Leigh Grodsky (Raymore, Missouri);  Richard Brow (Rolla, Missouri);  Melissa Malone Teague (Albuquerque, New Mexico)
ABSTRACT A tamper-evident glass and methods of using the tamper-evident glass are provided herein. The tamper-evident glass comprising at least a first plurality of tamper-evident elements, which may be unique or near unique to each manufacturing of tam per-evident glass. The initial state of tamper-evident glass and positioning of the plurality of tamper-evident elements may be mapped through digital scanning to create a digital file of the current state of the tamper-evident glass. The tamper-evident glass may be scanned again to create a new digital file for comparison and to determine if a tampering event has occurred. The tamper-evident elements may include any combination of inorganic fluorescent material, crystals grown through nucleation and crystallization, or added colorants.
FILED Monday, February 27, 2023
APPL NO 18/174958
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0002 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875934 Wang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Jian-Ping Wang (Shoreview, Minnesota);  Md Mehedi (Minneapolis, Minnesota);  YanFeng Jiang (Minneapolis, Minnesota);  Bin Ma (Roseville, Minnesota);  Delin Zhang (Minneapolis, Minnesota);  Fan Zhang (Minneapolis, Minnesota);  Jinming Liu (Minneapolis, Minnesota)
ABSTRACT The disclosure is directed to an iron-nitride material having a polycrystalline microstructure including a plurality of elongated crystallographic grains with grain boundaries, the iron-nitride material including at least one of an α″-Fe16N2 phase and a body-center-tetragonal (bct) phase comprising Fe and N. The disclosure is also directed a method producing an iron-nitride material. The method includes some combinations of preparing a raw material comprising iron, carrying out a microstructure build-up by annealing the prepared raw material at an elevated temperature and subsequently quenching the prepared raw material to produce a microstructure build-up material, annealing the microstructure build-up material, reducing the microstructure build-up material in a hydrogen environment, nitriding the reduced material to produce a nitrided material and subsequently quenching the nitrided material to a martensitic transformation temperature, stress annealing the nitrided material, and magnetic field annealing the stress-annealed material.
FILED Tuesday, May 28, 2019
APPL NO 16/423516
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 21/0622 (20130101)

Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering
C21D 2201/05 (20130101)
C21D 2211/008 (20130101)

Alloys
C22C 38/001 (20130101)
C22C 38/06 (20130101)
C22C 38/16 (20130101)
C22C 2200/04 (20130101)
C22C 2202/02 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/03 (20130101)
H01F 1/0009 (20130101)
H01F 1/10 (20130101)
H01F 41/0253 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876057 Trujillo et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
ASSIGNEE(S) Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri)
INVENTOR(S) Joshua Joseph Trujillo (Overland Park, Kansas);  Payman Zarkesh-Ha (Albuquerque, New Mexico)
ABSTRACT Systems, methods, circuits, and devices for providing and using transistors in a physically unclonable function (PUF) circuit. The transistors comprise a split source drain configuration including one or more inflection segments that increase process variations between the transistors such that each transistor generates a unique output signal.
FILED Friday, January 06, 2023
APPL NO 18/150942
ART UNIT 2815 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/576 (20130101) Original (OR) Class
H01L 29/78 (20130101)
H01L 29/0843 (20130101)

Pulse Technique
H03K 3/0315 (20130101)

Electronic Memory Devices
H10B 10/12 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876165 Pozin et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) DURACELL U.S. OPERATIONS, INC. (Wilmington, Delaware);  NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) DURACELL U.S. OPERATIONS, INC. (Wilmington, Delaware);  NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico)
INVENTOR(S) Michael Pozin (Brookfield, Connecticut);  Walter Fred Paxton (Albuquerque, New Mexico);  Bryan James Kaehr (Albuquerque, New Mexico)
ABSTRACT A battery cell comprising a composite water-responsive safety layer and/or composite water- and pH-responsive safety layer to protect against tissue damage and/or electrolysis, when the battery cell is exposed to aqueous solution or tissue, is provided. The composite water-responsive safety layer and/or composite water- and pH-responsive safety layer is adapted to change from a non-electronically conducting state to an electronically conducting state.
FILED Monday, July 18, 2022
APPL NO 17/866895
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0427 (20130101) Original (OR) Class
H01M 50/103 (20210101)
H01M 50/107 (20210101)
H01M 50/109 (20210101)
H01M 50/121 (20210101)
H01M 50/124 (20210101)
H01M 50/1245 (20210101)
H01M 2200/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876168 Hersam et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Mark C. Hersam (Wilmette, Illinois);  Kan-Sheng Chen (Chicago, Illinois);  Ethan B. Secor (Chicago, Illinois)
ABSTRACT Composites comprising anode and cathode active materials conformally coupled to few-layered graphene, corresponding electrodes and related methods of preparation.
FILED Wednesday, July 07, 2021
APPL NO 17/369058
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/133 (20130101)
H01M 4/134 (20130101)
H01M 4/136 (20130101)
H01M 4/139 (20130101)
H01M 4/0416 (20130101)
H01M 4/505 (20130101)
H01M 4/625 (20130101)
H01M 4/1393 (20130101)
H01M 10/0525 (20130101) Original (OR) Class
H01M 2004/027 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876174 Visco et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) PolyPlus Battery Company (Berkeley, California)
ASSIGNEE(S) PolyPlus Battery Company (Berkeley, California)
INVENTOR(S) Steven J. Visco (Berkeley, California);  Vitaliy Nimon (San Francisco, California);  Yevgeniy S. Nimon (Danville, California);  Bruce D. Katz (Moraga, California)
ABSTRACT A sulfide glass solid electrolyte sheet can be protected from reaction with moisture by a thin metal layer coating converted to a thin electrochemically functional and protective compound layer. The converted protective compound layer is electrochemically functional in that it allows for through transport of lithium ions.
FILED Monday, February 27, 2023
APPL NO 18/175374
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0525 (20130101)
H01M 10/0562 (20130101) Original (OR) Class
H01M 50/403 (20210101)
H01M 50/437 (20210101)
H01M 50/451 (20210101)
H01M 50/457 (20210101)
H01M 2300/0068 (20130101)
H01M 2300/0094 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876178 Xu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland);  The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland);  The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Kang Xu (Potomac, Maryland);  Chunsheng Wang (Silver Spring, Maryland);  Chongyin Yang (College Park, Maryland)
ABSTRACT The present invention is directed to aqueous solid state electrolytes that comprise a fluoride additive to stabilize the interface between the anode and aqueous electrolyte. The present invention is also directed to methods of making the solid state electrolyte materials and methods of using the solid state electrolyte materials in batteries and other electrochemical technologies.
FILED Friday, August 24, 2018
APPL NO 16/641895
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/131 (20130101)
H01M 4/134 (20130101)
H01M 4/386 (20130101)
H01M 4/505 (20130101)
H01M 4/667 (20130101)
H01M 4/5835 (20130101)
H01M 10/0525 (20130101)
H01M 10/0567 (20130101) Original (OR) Class
H01M 2004/021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876212 Vissers
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) Vissers Battery Corporation (Wheaton, Illinois)
ASSIGNEE(S) Vissers Battery Corporation (Wheaton, Illinois)
INVENTOR(S) Daniel R. Vissers (Wheaton, Illinois)
ABSTRACT A battery includes a fluid negative electrode and a fluid positive electrode separated by a solid electrolyte at least when the electrodes and electrolyte are at an operating temperature. The solid electrolyte comprises a salt formed by ions of the negative electrode material forming the fluid negative electrode. In one example, the fluid negative electrode comprises lithium (Li), the fluid positive electrode comprises sulfur (S) and the solid electrolyte comprises lithium iodide (LiI).
FILED Thursday, January 20, 2022
APPL NO 17/579918
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/136 (20130101) Original (OR) Class
H01M 4/0471 (20130101)
H01M 4/1397 (20130101)
H01M 10/39 (20130101)
H01M 10/63 (20150401)
H01M 2004/027 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876225 Jun et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) SAMSUNG ELECTRONICS CO., LTD. (Gyeonggi-Do, South Korea);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  LAWRENCE BERKELEY NATIONAL LABORATORY (Berkeley, California)
INVENTOR(S) KyuJung Jun (Albany, California);  Gerbrand Ceder (Orinda, California);  Yan Wang (Brookline, Massachusetts);  Lincoln Miara (Lincoln, Massachusetts);  Yan Zeng (Albany, California);  Yihan Xiao (Berkeley, California)
ABSTRACT A solid-state ion conductor including a compound of Formula 1:
Li1+(4−a)yAayM1−yXO5  Formula 1
wherein, in Formula 1, A is an element of Groups 1 to 3 or 11 to 13, or a combination thereof, wherein an oxidation state a of A is 1≤a≤3, M is an element having an oxidation state of +4 of Groups 4 or 14, or a combination thereof, X is an element having an oxidation state of +5 of Groups 5, 15, 17, or a combination thereof, and 0<y≤1.
FILED Monday, May 17, 2021
APPL NO 17/322325
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/58 (20130101) Original (OR) Class
H01M 4/382 (20130101)
H01M 4/0407 (20130101)
H01M 4/581 (20130101)
H01M 4/582 (20130101)
H01M 4/662 (20130101)
H01M 10/056 (20130101)
H01M 10/0525 (20130101)
H01M 2004/027 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876398 Heath et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  The Board of Regents of the University of Texas System (Austin, Texas);  Wayne State University (Detroit, Michigan)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico);  The Board of Regents of the University of Texas System (Austin, Texas);  Wayne State University (Detroit, Michigan)
INVENTOR(S) Jason E. Heath (Edgewood, New Mexico);  Gungor Didem Beskardes (Albuquerque, New Mexico);  Wallace McAliley (Golden, Colorado);  Chester J. Weiss (Sandia Park, New Mexico);  Mohsen Ahmadian-Tehrani (Austin, Texas);  David T. Chapman (Austin, Texas);  Leela Arava (Detroit, Michigan)
ABSTRACT Autonomous wireless sensors in subsurface environments can be charged while present in the subsurface environment to allow the sensors to measure and wirelessly transmit measurements. The sensors rely upon a contrast agent to provide a power flow path to the sensors.
FILED Monday, March 02, 2020
APPL NO 16/806742
ART UNIT 2881 — Optics
CURRENT CPC
Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/267 (20130101)
E21B 47/06 (20130101)
E21B 47/07 (20200501)
E21B 47/13 (20200501)
E21B 49/00 (20130101)
E21B 49/0875 (20200501)
E21B 2200/20 (20200501)

Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 21/02 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/02 (20130101) Original (OR) Class
H02J 50/001 (20200101)
H02J 50/80 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876833 Lyle
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Joshua A Lyle (Chicago, Illinois)
ABSTRACT Disclosed herein are systems, methods, and storage media for thwarting cyber-attacks and data theft. A computing system receives packets and compares with a configuration resource. The computing system determines that the packet does not match the configuration resource and transmits a packet to a decoy environment via an SDN switch. The decoy environment is configured to generate time-out, service unavailable, or restricted access messages. In some embodiments, the computing system determines the packet does match the configuration and transmits the packet to a production network via an SDN switch. The SDN switch is communicatively connected to the decoy environment through a first channel and communicatively connected to a production environment through a separate second channel. The computing system is further configured to create and transmit to the SDN switch, rules to manage transmitting the packet to either the decoy environment or the production environment.
FILED Thursday, August 15, 2019
APPL NO 16/542201
ART UNIT 2452 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 45/38 (20130101)
H04L 45/64 (20130101)
H04L 47/2441 (20130101)
H04L 49/354 (20130101)
H04L 63/166 (20130101)
H04L 63/1491 (20130101) Original (OR) Class
H04L 2101/622 (20220501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11877521 Solovyov
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Brookhaven Technology Group, Inc. (Stony Brook, New York)
ASSIGNEE(S) Brookhaven Technology Group, Inc. (Stony Brook, New York)
INVENTOR(S) Vyacheslav Solovyov (Rocky Point, New York)
ABSTRACT A multi-filament high temperature superconducting cable having improved AC current carrying capacity, quench resistance and flexibility. The multi-filament cable is formed from a plurality of stacked exfoliated filaments which provide current sharing between adjacent superconducting layers.
FILED Friday, June 08, 2018
APPL NO 16/620636
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines
H02G 15/34 (20130101)

Electric solid-state devices not otherwise provided for
H10N 60/0128 (20230201) Original (OR) Class
H10N 60/203 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11872311 Lin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Wenbin Lin (Chicago, Illinois);  Demin Liu (Round Lake, Illinois);  Joseph Della Rocca (Blue Bell, Pennsylvania);  Stephanie Kramer (Johnson City, Tennessee);  Christopher Y. Poon (Carlsbad, California)
ABSTRACT Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents.
FILED Tuesday, February 25, 2020
APPL NO 16/800855
ART UNIT RD00 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/14 (20130101)
A61K 9/0019 (20130101)
A61K 9/127 (20130101) Original (OR) Class
A61K 9/5115 (20130101)
A61K 9/5123 (20130101)
A61K 9/5146 (20130101)
A61K 31/663 (20130101)
A61K 31/675 (20130101)
A61K 47/548 (20170801)
A61K 47/6925 (20170801)
A61K 47/6929 (20170801)
A61K 49/00 (20130101)
A61K 51/1244 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/08 (20180101)
A61P 19/10 (20180101)
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872504 Yagoobi et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
ASSIGNEE(S) Worcester Polytechnic Institute (Worcester, Massachusetts)
INVENTOR(S) Jamal S. Yagoobi (Hopkinton, Massachusetts);  Mengqiao Yang (Worcester, Massachusetts);  Mehrnoush F. Dardashti (Worcester, Massachusetts)
ABSTRACT An atomizing spray dryer employs one or more stages defined by ultrasonic transducers in close proximity to a liquid feed opening forming a path of an atomization flow for producing uniform droplets from a close tolerance with the transducer. The atomization flow exits a gap between the transducer and an outer edge of the opening, such that the passed liquid is responsive to an oscillation of the transducer for forming the droplets. A conical or other suitably shaped transducer engages a substantially round liquid feed opening. Subsequent stages may include a circular, ring, or other suitable shape aligned to receive the atomization flow from a circumference of the conical base, or may also take any suitable shape, preferably to receive droplets directed by the first stage.
FILED Wednesday, June 29, 2022
APPL NO 17/853152
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 1/18 (20130101) Original (OR) Class
B01D 1/20 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 2/02 (20130101)

Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 17/0607 (20130101)
B05B 17/0623 (20130101)
B05B 17/0646 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872610 Quigley et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Loci Controls, Inc. (Wareham, Massachusetts)
ASSIGNEE(S) Loci Controls, Inc. (Wareham, Massachusetts)
INVENTOR(S) Peter Quigley (Duxbury, Massachusetts);  Ian Martin (Sharon, Massachusetts);  Joseph G. Michels (New York, New York);  Melinda Sims (Seattle, Washington)
ABSTRACT A control system for controlling extraction of landfill gas from a landfill via a gas extraction system comprising well piping, the landfill gas having a first temperature when extracted, the control system comprising: a gas composition chamber coupled to the well piping and comprising at least one sensor configured to measure one or more characteristics of a landfill gas sample in the gas composition chamber; a temperature control mechanism configured to heat the landfill gas sample in the gas composition chamber to a second temperature at least a threshold amount greater than the first temperature; and a controller configured to control the at least one sensor to measure the one or more characteristics of the landfill gas sample in the gas composition chamber when a temperature of the landfill gas sample in the gas composition chamber is at least the threshold amount greater than the first temperature.
FILED Thursday, February 04, 2021
APPL NO 17/167539
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Disposal of Solid Waste
B09B 1/00 (20130101)
B09B 1/006 (20130101) Original (OR) Class

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/12 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2294 (20130101)
G01N 33/0016 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 3/22 (20130101)

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/30 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873504 Doudna et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Jennifer A Doudna (Berkeley, California);  Jillian F. Banfield (Berkeley, California);  David Burstein (Berkeley, California);  Lucas Benjamin Harrington (Berkeley, California);  Steven C. Strutt (Berkeley, California)
ABSTRACT The present disclosure provides CasX proteins, nucleic acids encoding the CasX proteins, and modified host cells comprising the CasX proteins and/or nucleic acids encoding same. CasX proteins are useful in a variety of applications, which are provided. The present disclosure provides CasX guide RNAs that bind to and provide sequence specificity to the CasX proteins, nucleic acids encoding the CasX guide RNAs, and modified host cells comprising the CasX guide RNAs and/or nucleic acids encoding same. CasX guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides archaeal Cas9 polypeptides and nucleic acids encoding same, as well as their associated archaeal Cas9 guide RNAs and nucleic acids encoding same.
FILED Thursday, September 28, 2017
APPL NO 16/335516
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 19/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/06 (20130101)
C07K 2319/09 (20130101)
C07K 2319/20 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/1007 (20130101)
C12N 9/1025 (20130101)
C12N 15/52 (20130101)
C12N 15/62 (20130101)
C12N 15/74 (20130101)
C12N 15/85 (20130101)
C12N 15/86 (20130101)
C12N 15/88 (20130101)
C12N 15/102 (20130101)
C12N 15/113 (20130101)
C12N 15/902 (20130101)
C12N 15/8509 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2740/13043 (20130101)
C12N 2740/16043 (20130101)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873544 Kaner et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Richard B. Kaner (Pacific Palisades, California);  Sarah H. Tolbert (Encino, California);  Reza Mohammadi (Los Angeles, California);  Andrew T. Lech (Los Angeles, California);  Miao Xie (Los Angeles, California)
ABSTRACT A composition includes tungsten (W); at least one element selected form the group of elements consisting of boron (B), beryllium (Be) and silicon (Si); and at least one element selected from the group of elements consisting of titanium (Ti), vanadium (V), chromium (Cr), manganese (Mn), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), zirconium (Zr), niobium (Nb), molybdenum (Mo), ruthenium (Ru), hafnium (Hf), tantalum (Ta), rhenium (Re), osmium (Os), iridium (Ir), lithium (Li) and aluminum (Al). The composition satisfies the formula W1-xMxXy wherein X is one of B, Be and Si; M is at least one of Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Zr, Nb, Mo, Ru, Hf, Ta, Re, Os, Ir, Li and Al; x is at least 0.001 and less than 0.999; and y is at least 4.0. A tool is made from or coated with this composition.
FILED Thursday, June 25, 2020
APPL NO 16/912396
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 9/04 (20130101)
B22F 2005/001 (20130101)
B22F 2009/041 (20130101)

Alloys
C22C 1/02 (20130101)
C22C 1/045 (20130101)
C22C 1/1084 (20130101)
C22C 27/04 (20130101) Original (OR) Class
C22C 29/14 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 30/00 (20130101)
C23C 30/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873573 Cao
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
INVENTOR(S) Gang Cao (Broomfield, Colorado)
ABSTRACT Various embodiments include a device for producing structurally modified materials. In some embodiments, the device includes a floating zone furnace which holds a feed rod in contact with seed crystal. One or more laser diodes are then used to heat a portion of the feed rod and cause it to transition to a molten state. A magnetic field is applied to the floating zone to change the underlying crystal structure of the material as it solidifies upon exiting the floating zone. In some instances, the changes may include manipulating the bond angle of the crystal structure or altering the unit cell volume of the crystal. Changes in the crystal structure directly affect the electrical resistivity and/or the magnetization and other physical properties of the crystal.
FILED Thursday, January 21, 2021
APPL NO 17/794108
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 13/24 (20130101)
C30B 13/30 (20130101) Original (OR) Class
C30B 29/22 (20130101)
C30B 30/04 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 6/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873788 Son et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Steven Forrest Son (West Lafayette, Indiana);  Kyle Uhlenhake (Lafayette, Indiana);  Diane Collard (West Lafayette, Indiana);  Mateo Gomez (West Lafayette, Indiana)
ABSTRACT An igniter system and method for igniting a propellant by an optical energy source. The igniter system including an igniter composite and a propellant. The igniter composite including a reactive component and a fluoropolymer. The propellant is coupled to the igniter composite. The igniter composite has a composition including nano-aluminum at ideal stoichiometry in polyvinylidene fluoride. The igniter composite is configured to achieve a sustained ignition from a wavelength emitted from the optical energy source. The wavelength is between around 250 nanometers to around 1100 nanometers.
FILED Monday, February 28, 2022
APPL NO 17/682026
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Jet-propulsion Plants
F02K 9/95 (20130101)

Ignition, Other Than Compression Ignition, for Internal-combustion Engines; Testing of Ignition Timing in Compression-ignition Engines
F02P 23/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874184 Merrell et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Nano Composite Products, Inc. (Orem, Utah)
ASSIGNEE(S) Nano Composite Products, Inc. (Orem, Utah)
INVENTOR(S) Aaron Jake Merrell (Orem, Utah);  David T. Fullwood (Provo, Utah);  Anton E. Bowden (Lindon, Utah);  Taylor D. Remington (Provo, Utah)
ABSTRACT In one general aspect, a composite foam comprises a non-layered mixture of a polymeric foam with a plurality of voids; and a plurality of conductive fillers disposed in the polymeric foam. The conductive fillers are disposed in an even manner from outer surface to outer surface. In some implementations, the conductive fillers are up to 25% by weight of the composite foam. In some implementations, the composite foam may be used as padding. In some implementations, the composite foam may be used as a strain gauge. In some implementations, the foam may be in contact with a voltage detector.
FILED Monday, May 09, 2022
APPL NO 17/662607
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/04 (20130101) Original (OR) Class
G01L 1/06 (20130101)
G01L 1/16 (20130101)
G01L 1/18 (20130101)
G01L 1/20 (20130101)
G01L 5/0052 (20130101)

Electric solid-state devices not otherwise provided for
H10N 30/092 (20230201)
H10N 30/852 (20230201)

Technical Subjects Covered by Former US Classification
Y10T 29/49117 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874343 Javor et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Joshua Javor (Cambridge, Massachusetts);  David Bishop (Brookline, Massachusetts);  David Campbell (Brookline, Massachusetts);  Matthias Imboden (St. Blaise, Switzerland)
ABSTRACT A gradiometer includes a at least one magnet attached to a beam. The magnet moves in response to a magnetic force. A sensing element is configured to measure movement or deflection of the beam or magnet. The gradiometer is configured to determine a gradient of a magnetic field acting on the first magnet based on movement of the magnet. The gradiometer can further measure higher order gradients.
FILED Tuesday, February 21, 2023
APPL NO 18/112229
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/022 (20130101) Original (OR) Class
G01R 33/038 (20130101)
G01R 33/0052 (20130101)
G01R 33/0385 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874480 Guo et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Lingjie Jay Guo (Ann Arbor, Michigan);  Xi Chen (San Jose, California)
ABSTRACT A plasmonic device incorporating a special hyperbolic metamaterial (HMM) metamaterial is used for plasmonic lithography, including ultraviolet (UV) lithography. It may be a Type II HMM (ϵ<0 and ϵ>0) whose tangential component of the permittivity ϵis close to zero. Due to the high anisotropy of the Type II epsilon near zero (ENZ) HMM, only one plasmonic mode can propagate horizontally with low loss in a waveguide system with ENZ HMM as its core. In certain aspects, a Type II ENZ HMM comprises alternating layers of aluminum/aluminum oxide films and the associated unusual mode of light transmission is used to expose a photosensitive layer in a specially designed lithography system. Methods for making patterns of nanofeatures via such plasmonic lithography are also provided, including as a plasmonic roller device.
FILED Thursday, December 20, 2018
APPL NO 16/956334
ART UNIT 2871 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 5/008 (20130101) Original (OR) Class
G02B 5/1809 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875272 Kim et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Non-Profit Organization (NPO)
Semiconductor Research Corporation (SRC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Hyung-il Kim (Minneapolis, Minnesota);  Ibrahim Ahmed (Minneapolis, Minnesota);  Po-wei Chiu (Minneapolis, Minnesota)
ABSTRACT Compute engine circuitry configured to represent a spin network mapping of a graph representing a combinatorial optimization problem includes a plurality of ring oscillator cells, each of which includes a ring oscillator having an oscillator output, at least one coupling block, and a read block. Each coupling block connects the ring oscillator of the cell to the ring oscillator of one of a plurality of neighboring cells to form a coupled ring oscillator. The read block generates a state output for each coupled ring oscillator that indicates whether the coupled ring oscillator is in one of a same-phase state, in which the connected ring oscillators oscillate in phase with each other, and an opposite-phase state, in which the connected ring oscillators oscillate in an opposite phase from each other. A controller is configured to output a total energy of the mapping based on the state outputs.
FILED Friday, March 26, 2021
APPL NO 17/213396
ART UNIT 2849 — AI & Simulation/Modeling
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Electric Digital Data Processing
G06F 17/10 (20130101)
G06F 17/11 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/01 (20230101) Original (OR) Class
G06N 5/04 (20130101)
G06N 7/01 (20230101)
G06N 7/08 (20130101)
G06N 10/00 (20190101)

Pulse Technique
H03K 3/0315 (20130101)
H03K 5/19 (20130101)
H03K 19/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875482 Menon et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) University of Utah Research Foundation (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Rajesh Menon (Salt Lake City, Utah);  Ganghun Kim (Salt Lake City, Utah);  Kyle Isaacson (Salt Lake City, Utah)
ABSTRACT Technology is described for methods and systems for imaging an object (110). The method can include an image sensor (116) exposed to light (114) from an object (110) without passing the light through an image modification element. Light intensity of the light (114) can be stored as data in a medium. The image data can be analyzed at a processor (902) as a reconstructed image of the object (110).
FILED Tuesday, May 31, 2022
APPL NO 17/828645
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/003 (20130101) Original (OR) Class
G06T 5/50 (20130101)

Pictorial Communication, e.g Television
H04N 23/60 (20230101)
H04N 23/811 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875701 Hong et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Minsik Hong (Tucson, Arizona);  Jerzy W Rozenblit (Tucson, Arizona)
ABSTRACT An adaptive force guidance system for laparoscopic surgery skills training includes self-adjusting fuzzy sliding mode controllers and switching mode controllers to provide proper force feedback. Using virtual fixtures, the system restrictS motions and/or guide a trainee to navigate a surgical instrument in a 3D space in a manner that mimics a human instructor who would teach trainees by holding their hands. The self-adjusting controllers incorporate human factors such as different force sensitivity and proficiency level.
FILED Monday, November 08, 2021
APPL NO 17/520852
ART UNIT 3715 — Amusement and Education Devices
CURRENT CPC
Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 19/003 (20130101)
G09B 23/285 (20130101) Original (OR) Class

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 40/63 (20180101)
G16H 70/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876303 Baniya et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona)
INVENTOR(S) Prabhat Baniya (Tucson, Arizona);  Kathleen L. Melde (Tucson, Arizona)
ABSTRACT A multichip system includes a plurality of processor chips each having one or more cores and a plurality of antenna module for establishing interchip wireless communication. Each antenna module is disposed on a chip. At least one antenna module includes an antenna element array and a Butler matrix. The antenna element array includes n circular patch antenna elements for 360° end-fire scanning, where n is equal to 4 or a multiple thereof. The Butler matrix has n/4 submatrices. Each submatrix include two input 90° hybrids each having two outputs and two inputs for selectively receiving signals from a transceiver. The Butler matrix also includes two output 90° hybrids each having two outputs and two inputs. The two inputs of each output 90° hybrid are coupled to an output of different ones of the input 90° hybrids. Each output of the output 90° hybrids are coupled to a different antenna element.
FILED Tuesday, July 16, 2019
APPL NO 17/260808
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 1/38 (20130101)
H01Q 1/2283 (20130101)
H01Q 3/40 (20130101) Original (OR) Class
H01Q 21/065 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/181 (20130101)
H05K 1/0243 (20130101)
H05K 2201/10098 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876569 Prothero et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Astrapi Corporation (Dallas, Texas)
ASSIGNEE(S) Astrapi Corporation (Dallas, Texas)
INVENTOR(S) Jerrold Prothero (Delray Beach, Florida);  Tanay Bhatt (Richardson, Texas)
ABSTRACT Systems, devices, software, and methods of the present invention enable frequency-based signal power analyses in software suitable for signal with either stationary and non-stationary spectrums. The methods that may be used throughout various systems including transmitters receivers, repeater, controllers, monitors, etc. and in software simulators to enable various signal power calculations and analyses, such as frequency spectrum analysis, throughout operating systems and that may be consistently applied in system design and operation simulations.
FILED Sunday, March 15, 2020
APPL NO 16/819126
ART UNIT 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission
H04B 17/0087 (20130101)
H04B 17/318 (20150115) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876758 Mueller et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Clinc, Inc. (Ann Arbor, Michigan)
ASSIGNEE(S) Clinc, Inc. (Ann Arbor, Michigan)
INVENTOR(S) Matthew Mueller (Ann Arbor, Michigan);  Connor Witt (Ann Arbor, Michigan);  Jamal El-Mokadem (Farmington Hills, Michigan)
ABSTRACT Systems and methods for configuring a dialogue guidance graph that governs a set of operations of an automated dialogue system and that includes encoding a recall operation to a target graphical node of the graph, wherein the recall operation causes: an accessing of a temporary data storage storing a log of data of an active dialogue session between a user and the automated dialogue system, an assessment of a terminality attribute associated with the target graphical node, a determination of whether the terminality attribute is disabled or enabled, wherein if the terminality attribute is disabled, the recall operation, causes the automated dialogue system to revert the active dialogue session to the target graphical node to perform one or more dialogue-based operations between the user and the automated dialogue system that converts the terminality attribute of the target graphical node from the disabled state to the enabled state.
FILED Monday, September 18, 2023
APPL NO 18/369496
ART UNIT 2658 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Electric Digital Data Processing
G06F 40/35 (20200101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 51/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11872628 Sherman et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Powdermet, Inc. (Euclid, Ohio)
ASSIGNEE(S) Powdermet, Inc. (Euclid, Ohio)
INVENTOR(S) Andrew J. Sherman (Mentor, Ohio);  Brian Werry (Euclid, Ohio)
ABSTRACT A structured three-phase composite which include a metal phase, a ceramic phase, and a gas phase that are arranged to create a composite having low thermal conductivity, having controlled stiffness, and a CTE to reduce thermal stresses in the composite when exposed to cyclic thermal loads. The structured three-phase composite is useful for use in structures such as, but not limited to, heat shields, cryotanks, high speed engine ducts, exhaust-impinged structures, and high speed and reentry aeroshells.
FILED Thursday, August 23, 2018
APPL NO 16/110600
ART UNIT 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal
B21D 3/00 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/04 (20130101)
B22F 3/16 (20130101)
B22F 3/1007 (20130101)
B22F 3/1007 (20130101)
B22F 3/1112 (20130101) Original (OR) Class
B22F 2003/1106 (20130101)
B22F 2201/20 (20130101)
B22F 2998/10 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)
B22F 2999/00 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/16 (20130101)
B32B 5/18 (20130101)
B32B 5/20 (20130101)

Alloys
C22C 1/1084 (20130101)
C22C 1/1084 (20130101)
C22C 32/0031 (20130101)
C22C 32/0036 (20130101)
C22C 32/0078 (20130101)
C22C 49/00 (20130101)
C22C 49/06 (20130101)
C22C 49/11 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872691 Alizadehyazdi et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Vahid Alizadehyazdi (Chicago, Illinois);  Matthew Spenko (Chicago, Illinois)
ASSIGNEE(S) ILLINOIS INSTITUTE OF TECHNOLOGY (Chicago, Illinois)
INVENTOR(S) Vahid Alizadehyazdi (Chicago, Illinois);  Matthew Spenko (Chicago, Illinois)
ABSTRACT An adhesive apparatus with an electrostatic adhesive including a microstructured adhesive disposed over an electrode and/or a piezoelectric element. The adhesive can be added to any robotic gripper, such as a gripper finger formed of a flexible material and including a grip surface. The electrode and/or a piezoelectric element can be used for applying an electrostatic field and/or ultrasonic vibration, configured for cleaning the microstructured adhesive, releasing the adhesive, and/or sensing a load on the adhesive apparatus.
FILED Thursday, April 23, 2020
APPL NO 16/856515
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General
B06B 1/0662 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 15/008 (20130101) Original (OR) Class
B25J 15/086 (20130101)

Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives
C09J 7/20 (20180101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/60 (20130101)

Electric solid-state devices not otherwise provided for
H10N 30/87 (20230201)
H10N 30/1051 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873485 Hochrein et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Lisa Hochrein (Chicago, Illinois);  Mikhail H. Hanewich-Hollatz (Pasadena, California);  Zhewei Chen (Pasadena, California);  Heyun Li (Pasadena, California);  Shashank Gandhi (Pasadena, California);  Marianne Bronner (Pasadena, California);  Niles A. Pierce (South Pasadena, California)
ABSTRACT Programmable guide RNAs (gRNAs) play a central role in the CRISPR revolution sweeping biology and medicine by directing the function of a Cas protein effector to a target gene of choice. To achieve programmable control over regulatory scope, the activity of a conditional guide RNA (cgRNA) depends on the presence or absence of an RNA trigger, allowing for cell-selective regulation of CRISPR/Cas function. Unlike a standard gRNA, a cgRNA is programmable at multiple levels, with the target-binding sequence controlling the target of Cas activity (edit, silence, induce, or bind a gene of choice) and the trigger binding sequence controlling the scope of Cas activity. cgRNA mechanisms that are allosteric allow for independent design of the target and trigger sequences, providing the flexibility to select the regulatory target and scope independently. Disclosed herein are allosteric cgRNA mechanisms for both ON→OFF logic (conditional inactivation by an RNA trigger) and OFF→ON logic (conditional activation by an RNA trigger). Allosteric cgRNAs enable restriction of CRISPR/Cas function to a desired cell type, tissue, organ, or disease state. Allosteric cgRNAs provide a versatile platform for cell-selective and tissue-selective research tools, biotechnologies, diagnostics, and therapeutics.
FILED Tuesday, January 25, 2022
APPL NO 17/584237
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101) Original (OR) Class
C12N 2310/15 (20130101)
C12N 2310/20 (20170501)
C12N 2310/344 (20130101)
C12N 2310/531 (20130101)
C12N 2310/532 (20130101)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873590 Williams
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Tiffany Williams (Cleveland, Ohio)
ABSTRACT A triaxially hybrid braid reinforcement material for polymer matrix composites. The braid includes hybrid tows, which include at least one carbon fiber tow commingled with carbon nanotube yarns to introduce toughness to the hybrid tows. The hybrid tows may be arranged in any and all of the braiding directions. The braid may also include carbon fiber tows, which can be arranged in the axial direction or other braiding directions not occupied by the hybrid tows. The braid is infiltrated with resin, which is impregnated into the braid and cured, to form the toughened polymer matrix composite.
FILED Friday, August 21, 2020
APPL NO 16/999683
ART UNIT 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Braiding or Manufacture of Lace, Including Bobbin-net or Carbonised Lace; Braiding Machines; Braid; Lace
D04C 1/12 (20130101) Original (OR) Class

Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials
D06M 15/55 (20130101)

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2101/122 (20130101)
D10B 2505/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11873915 Addona et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Brad M. Addona (Huntsville, Alabama);  James A. Richard (Grant, Alabama);  Maegan Rinehart Dawson (Iuka, Mississippi);  William Francis Sadowski (Huntsville, Alabama)
ABSTRACT A poppet valve apparatus has a valve body with an aperture rimmed by a first sealing surface, and a valve stem with an axially oriented cup at its tip with a spring disposed within the cup. The valve plate includes a sealing surface at its perimeter and also has a central pocket which receives a spheroid. The valve stem passes through a collar which is affixed to the valve plate to trap the spheroid beneath the spring so that the plate is pivotably coupled to the valve stem and also tolerates radial and lateral excursion to allow the valve plate to self-align and seal within the valve seat.
FILED Thursday, December 30, 2021
APPL NO 17/566068
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating
F16K 1/38 (20130101)
F16K 25/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874683 Morin et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Lee M. Morin (Houston, Texas);  Chad A. Shultz (Houston, Texas)
ABSTRACT A scissor assembly includes a scissor apparatus having a first scissor jaw and a second scissor jaw that are coupled together. The first scissor jaw has a first jaw face, and the second scissor jaw has a second jaw face that opposes the first jaw face. The scissor apparatus is configured to actuate between a closed position and a plurality of open positions. The scissor assembly includes a pivot pin extending through the first and second scissor jaws. The first and second jaws are configured to rotate around the pivot pin as the scissor apparatus actuates between the closed position and the open positions. The scissor assembly includes a dynamic pin positioned between the first jaw face and the second jaw face. The scissor assembly includes a biasing member positioned at least partially around the scissor apparatus and configured to bias the scissor apparatus toward the closed position.
FILED Monday, October 31, 2022
APPL NO 18/051290
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Control Devices or Systems Insofar as Characterised by Mechanical Features Only
G05G 1/04 (20130101) Original (OR) Class
G05G 5/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11877164 Barsoum et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Constellation Designs, LLC (Wayne, Pennsylvania)
ASSIGNEE(S) Constellation Designs, LLC (Wayne, Pennsylvania)
INVENTOR(S) Maged F. Barsoum (San Jose, California);  Christopher R. Jones (Pacific Palisades, California)
ABSTRACT Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation.
FILED Thursday, May 26, 2022
APPL NO 17/804305
ART UNIT 2632 — Digital Communications
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 13/255 (20130101)
H03M 13/6325 (20130101)

Transmission
H04B 15/00 (20130101)
H04B 17/336 (20150115)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0003 (20130101)
H04L 1/0009 (20130101)
H04L 27/3405 (20130101)
H04L 27/3483 (20130101)
H04L 27/3809 (20130101)

Wireless Communication Networks
H04W 24/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11872322 McCreery et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-ST)
APPLICANT(S) Zeteo Tech, Inc. (Sykesville, Maryland)
ASSIGNEE(S) Zeteo Tech, Inc. (Sykesville, Maryland)
INVENTOR(S) Thomas McCreery (Sykesville, Maryland);  Wayne A. Bryden (Sykesville, Maryland)
ABSTRACT Disclosed are microwave assisted methods and systems for decontaminating a variety of contaminated surfaces. The systems and methods comprise treating the surfaces with benign chemical formulations followed by exposing to microwave irradiation for short periods of time to achieve at least 6-log reduction in biological contaminants including spores of B. anthracis, B. thuringiensis, and P. roqueforti. Chemical formulations may comprise copper (II) chloride in water. The formulations may include a surfactant such as a polyethylene sorbitol ester surfactant.
FILED Friday, September 30, 2022
APPL NO 17/958068
ART UNIT 1799 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/12 (20130101) Original (OR) Class
A61L 2/18 (20130101)
A61L 2202/14 (20130101)
A61L 2202/16 (20130101)
A61L 2202/25 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11874912 McManus et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Kali McManus (Woodbridge, Virginia);  Kristi Harmel (Colorado Springs, Colorado);  Gregory Bennett (Colorado Springs, Colorado)
ABSTRACT Examples are directed toward a system and method relating to mobile screening. For example, a mobile screening vehicle includes a passenger scanner that performs security scanning of a passenger on the mobile screening vehicle. The mobile screening vehicle also includes a verification system that verifies, consistent with the security scanning of passengers, that passengers on the mobile screening vehicle are approved to proceed to a secure area of a travel venue.
FILED Thursday, February 16, 2023
APPL NO 18/110721
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 40/08 (20130101)
B60W 60/0024 (20200201)
B60W 60/00253 (20200201)
B60W 2540/043 (20200201)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3438 (20130101)
G01C 21/3484 (20130101)
G01C 21/3617 (20130101)

Electric Digital Data Processing
G06F 21/32 (20130101) Original (OR) Class
G06F 21/44 (20130101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/06315 (20130101)
G06Q 50/26 (20130101)
G06Q 50/30 (20130101)

Image or Video Recognition or Understanding
G06V 40/40 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11875566 Amini et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) Mohammadhadi Amini (Miami, Florida);  Naphtali D. Rishe (Miami, Florida);  Khandaker Mamun Ahmed (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Mohammadhadi Amini (Miami, Florida);  Naphtali D. Rishe (Miami, Florida);  Khandaker Mamun Ahmed (Miami, Florida)
ABSTRACT Systems and methods are provided for detecting one or more anomalous events in video. Histogram-based noise cleansing, higher-order deep convolutional neural network-based feature extraction, instance segmentation, instance summation, difference calculation, and normalization can be used. Human-in-loop systems and methods can facilitate human decisions for anomaly detection. The decision of an anomaly event can be made by, for example, the instance difference value(s).
FILED Tuesday, October 10, 2023
APPL NO 18/484039
ART UNIT 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 5/002 (20130101)
G06T 5/40 (20130101)
G06T 7/10 (20170101)
G06T 2207/10016 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30232 (20130101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101)
G06V 10/945 (20220101)
G06V 20/44 (20220101) Original (OR) Class
G06V 20/46 (20220101)
G06V 20/49 (20220101)
G06V 20/52 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11877157 Villanueva Gaviola et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) Apple Inc. (Cupertino, California)
ASSIGNEE(S) Apple Inc. (Cupertino, California)
INVENTOR(S) Haya Iris Villanueva Gaviola (San Jose, California);  Gianpaolo Fasoli (Burlingame, California);  Vinay Ganesh (San Jose, California);  Irene M. Graff (Cupertino, California);  Martijn Theo Haring (Utrecht, Netherlands);  Ahmer A. Khan (San Jose, California);  Franck Farian Rakotomalala (Dublin, California);  Gordon Y. Scott (Cupertino, California);  Ho Cheung Chung (San Jose, California);  Antonio Allen (San Jose, California);  Mayura Dhananjaya Deshpande (San Carlos, California);  Thomas John Miller (San Jose, California);  Christopher Sharp (Fort Myers, Florida);  David W. Silver (Los Altos, California);  Policarpo B. Wood (San Jose, California);  Ka Yang (Palo Alto, California)
ABSTRACT An embodiment includes a method to increase the efficiency of security checkpoint operations. A security checkpoint kiosk serves as a Relying Party System (RPS). The RPS establishes a secure local connection between the RPS and a User Mobile-Identification-Credential Device (UMD). The RPS sends a user information request to the UMD, via the secure local connection, seeking release of user information associated with a Mobile Identification Credential (MIC). The RPS obtains authentication of the user information received in response to the user information request. The RPS retrieves user travel information based on the user information. The RPS determines that the user travel information matches the user information. When the user travel information matches the user information, the RPS approves the user to proceed past the security checkpoint kiosk.
FILED Tuesday, August 10, 2021
APPL NO 17/398723
ART UNIT 2496 — Computer Networks
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/265 (20130101)

Wireless Communication Networks
H04W 4/80 (20180201)
H04W 12/02 (20130101)
H04W 12/037 (20210101)
H04W 12/47 (20210101)
H04W 12/69 (20210101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11872610 Quigley et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Loci Controls, Inc. (Wareham, Massachusetts)
ASSIGNEE(S) Loci Controls, Inc. (Wareham, Massachusetts)
INVENTOR(S) Peter Quigley (Duxbury, Massachusetts);  Ian Martin (Sharon, Massachusetts);  Joseph G. Michels (New York, New York);  Melinda Sims (Seattle, Washington)
ABSTRACT A control system for controlling extraction of landfill gas from a landfill via a gas extraction system comprising well piping, the landfill gas having a first temperature when extracted, the control system comprising: a gas composition chamber coupled to the well piping and comprising at least one sensor configured to measure one or more characteristics of a landfill gas sample in the gas composition chamber; a temperature control mechanism configured to heat the landfill gas sample in the gas composition chamber to a second temperature at least a threshold amount greater than the first temperature; and a controller configured to control the at least one sensor to measure the one or more characteristics of the landfill gas sample in the gas composition chamber when a temperature of the landfill gas sample in the gas composition chamber is at least the threshold amount greater than the first temperature.
FILED Thursday, February 04, 2021
APPL NO 17/167539
ART UNIT 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Disposal of Solid Waste
B09B 1/00 (20130101)
B09B 1/006 (20130101) Original (OR) Class

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/12 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2294 (20130101)
G01N 33/0016 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 3/22 (20130101)

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/30 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872634 Eonta et al.
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) MolyWorks Materials Corporation (Cloverdale, California)
ASSIGNEE(S) MolyWorks Material Corporation (Cloverdale, California)
INVENTOR(S) Christopher Paul Eonta (Los Gatos, California);  Andrew VanOs LaTOUR (Hayward, California);  Matthew Charles (Cloverdale, California);  Tom Reed (Hopland, California);  Kai Prager (Huntington Beach, California)
ABSTRACT An expeditionary additive manufacturing (ExAM) system [10] for manufacturing metal parts [20] includes a mobile foundry system [12] configured to produce an alloy powder [14] from a feedstock [16], and an additive manufacturing system [18] configured to fabricate a part using the alloy powder [14]. The additive manufacturing system [18] includes a computer system [50] having parts data and machine learning programs in signal communication with a cloud service. The parts data [56] can include material specifications, drawings, process specifications, assembly instructions, and product verification requirements for the part [20]. An expeditionary additive manufacturing (ExAM) method for making metal parts [20] includes the steps of transporting the mobile foundry system [12] and the additive manufacturing system [18] to a desired location; making the alloy powder [14] at the location using the mobile foundry system; and building a part [20] at the location using the additive manufacturing system [18].
FILED Friday, February 24, 2023
APPL NO 18/113863
ART UNIT 1738 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/24 (20130101)
B22F 8/00 (20130101)
B22F 9/082 (20130101) Original (OR) Class
B22F 9/082 (20130101)
B22F 10/00 (20210101)
B22F 10/28 (20210101)
B22F 10/34 (20210101)
B22F 10/85 (20210101)
B22F 10/85 (20210101)
B22F 12/82 (20210101)
B22F 12/84 (20210101)
B22F 12/84 (20210101)
B22F 2009/001 (20130101)
B22F 2009/0848 (20130101)
B22F 2999/00 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 40/00 (20141201)
B33Y 50/02 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876758 Mueller et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Clinc, Inc. (Ann Arbor, Michigan)
ASSIGNEE(S) Clinc, Inc. (Ann Arbor, Michigan)
INVENTOR(S) Matthew Mueller (Ann Arbor, Michigan);  Connor Witt (Ann Arbor, Michigan);  Jamal El-Mokadem (Farmington Hills, Michigan)
ABSTRACT Systems and methods for configuring a dialogue guidance graph that governs a set of operations of an automated dialogue system and that includes encoding a recall operation to a target graphical node of the graph, wherein the recall operation causes: an accessing of a temporary data storage storing a log of data of an active dialogue session between a user and the automated dialogue system, an assessment of a terminality attribute associated with the target graphical node, a determination of whether the terminality attribute is disabled or enabled, wherein if the terminality attribute is disabled, the recall operation, causes the automated dialogue system to revert the active dialogue session to the target graphical node to perform one or more dialogue-based operations between the user and the automated dialogue system that converts the terminality attribute of the target graphical node from the disabled state to the enabled state.
FILED Monday, September 18, 2023
APPL NO 18/369496
ART UNIT 2658 — Linguistics, Speech Processing and Audio Compression
CURRENT CPC
Electric Digital Data Processing
G06F 40/35 (20200101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 51/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11874504 Aksyuk et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Vladimir Anatolyevich Aksyuk (Gaithersburg, Maryland);  Christian Haffner (Binningen, Switzerland);  Henri J. Lezec (Silver Spring, Maryland);  Andreas Joerg (Bern, Switzerland);  Mikael Mazur (Gothenburg, Sweden);  Daniel Chelladurai (Zurich, Switzerland);  Jueg Leuthold (Neerach, Switzerland)
ABSTRACT Disclosed is an optoelectromechanical switch that includes: an optical feedline disposed on an isolation substrate that receives resonator light that is subject to optical communication to a resonator when a cavity length of the resonator supports an electromagnetic mode at the wavelength of the resonator light; a resonator including: a low refractive index optical layer and receives substrate electrical counter potential; a non-conductive spacer; the electrically conductive membrane and that receives a membrane electrical potential and deflects toward and away from the electrically conductive high-index optical waveguide based on a difference in potential between the membrane electrical potential and the substrate electrical counter potential; the cavity length that is variable and under electromechanical control.
FILED Thursday, September 30, 2021
APPL NO 17/490841
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/357 (20130101)
G02B 6/3536 (20130101) Original (OR) Class
G02B 6/29341 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/295 (20130101)

Multiplex Communication
H04J 14/0212 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11876211 Oleshko et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Vladimir Pavlovich Oleshko (Gaithersburg, Maryland);  Christopher Lloyd Soles (Boyds, Maryland);  Jabez Jenkins McClelland (Bethesda, Maryland)
ABSTRACT A prelithiated lithium ion battery includes: ion beam implanted lithium; a cathode; and an anode disposed on the cathode and an electrolyte in electrical communication with the cathode and the anode, the cathode or the anode including the ion beam implanted lithium such that: when the cathode includes the ion beam implanted lithium, the ion beam implanted lithium is present in an absence of solid electrolyte interface composition in the cathode; and when the anode includes the ion beam implanted lithium, the ion beam implanted lithium is present in an absence of solid electrolyte interface composition in the anode.
FILED Friday, September 11, 2020
APPL NO 17/018898
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/134 (20130101) Original (OR) Class
H01M 4/0423 (20130101)
H01M 4/661 (20130101)
H01M 4/1395 (20130101)
H01M 10/0525 (20130101)
H01M 50/409 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 11871862 Shenhar et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Joram Shenhar (Fairfax, Virginia);  Joel Locknauth Dewnandan (Bladensburg, Maryland);  William Albert Tartal (Baltimore, Maryland)
ABSTRACT A retractable arm device, system, and method with a locking mechanism for preventing items placed in a device or receptacle from getting stuck, damaged, or torn. The retractable arm includes an inner tube, a pawl, and an outer tube surrounding the inner tube. The inner tube slides within the outer tube and the pawl preventing the retractable arm from moving into an extended position under particular conditions. The retractable arm may be placed in a receptacle for items to prevent the door from being reopened before the door is fully closed.
FILED Friday, March 18, 2022
APPL NO 17/655513
ART UNIT 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Household or Table Equipment
A47G 29/22 (20130101)
A47G 29/122 (20130101)
A47G 29/1207 (20130101)
A47G 29/1251 (20170801) Original (OR) Class

Devices for Moving Wings into Open or Closed Position; Checks for Wings; Wing Fittings Not Otherwise Provided For, Concerned With the Functioning of the Wing
E05F 1/1008 (20130101)
E05F 5/08 (20130101)

Safes or Strong-rooms for Valuables; Bank Protection Devices; Safety Transaction Partitions
E05G 7/001 (20130101)

Indexing Scheme Relating to Hinges or Other Suspension Devices for Doors, Windows or Wings and Devices for Moving Wings into Open or Closed Position, Checks for Wings and Wing Fittings Not Otherwise Provided For, Concerned With the Functioning of the Wing
E05Y 2201/224 (20130101)
E05Y 2800/41 (20130101)
E05Y 2800/75 (20130101)
E05Y 2800/122 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11872597 Bombaugh et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Scott R. Bombaugh (Burke, Virginia);  Tuan A. Le (Fairfax, Virginia);  Charles P. McLellan (Fairfax, Virginia);  Christopher M. Stratton (Springfield, Virginia)
ABSTRACT A high throughput sorting device is disclosed. The device includes a first sorter and a second sorter, each of the first and second sorters having a plurality of cells each configured to support, carry, and deposit an item. The device can also include at least one shared chute extending below a portion of the first sorter and a portion of the second sorter. The at least one chute can be configured to receive an item deposited by each of the plurality of cells and transport the item to an endpoint. The device can also include a base configured to support the at least one shared chute and the first and second sorters.
FILED Thursday, August 05, 2021
APPL NO 17/395258
ART UNIT 3653 — Printing/Measuring and Testing
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 3/02 (20130101)
B07C 3/008 (20130101)
B07C 3/08 (20130101)
B07C 3/18 (20130101)
B07C 5/36 (20130101) Original (OR) Class

Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors
B65G 47/38 (20130101)
B65G 47/44 (20130101)
B65G 47/967 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11873628 Henry
FUNDED BY
Department of Agriculture (USDA)
Natural Resources Conservation Service (NRCS)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S) Christopher G. Henry (Stuttgart, Arkansas)
ABSTRACT A redundant meter measurement system includes a first water sensor configured to measure a first set of water use data and a second water sensor configured to measure a second set of water use data. The system also includes a controller communicatively coupled to the first water sensor and the second water sensor. The controller is configured to receive the first set of water use data from the first water sensor and receive the second set of water use data from the second water sensor. The controller is also configured to store the first set of water use data and the second set of water use data as a collection of water use data. The controller is also configured to enable transmission of the collection of water use data to a remote device.
FILED Thursday, August 05, 2021
APPL NO 17/394675
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Installations or Methods for Obtaining, Collecting, or Distributing Water
E03B 7/072 (20130101) Original (OR) Class

Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume
G01F 15/063 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Justice (DOJ) 

US 11875557 Xu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Department of Justice (DOJ)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Felix Juefei Xu (Pittsburgh, Pennsylvania);  Marios Savvides (Pittsburgh, Pennsylvania)
ABSTRACT The invention proposes a method of training a convolutional neural network in which, at each convolution layer, weights for one seed convolutional filter per layer are updated during each training iteration. All other convolutional filters are polynomial transformations of the seed filter, or, alternatively, all response maps are polynomial transformations of the response map generated by the seed filter.
FILED Monday, April 29, 2019
APPL NO 16/976409
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Electric Digital Data Processing
G06F 18/21 (20230101)
G06F 18/253 (20230101)
G06F 18/2414 (20230101)
G06F 18/21355 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/045 (20230101)
G06N 3/048 (20230101)
G06N 3/084 (20130101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101) Original (OR) Class
G06V 10/454 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11876345 Liang et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Spring, Texas)
INVENTOR(S) Di Liang (Santa Barbara, California);  Chih C. Shih (San Jose, California);  Kevin B. Leigh (Houston, Texas);  Geza Kurczveil (Santa Barbara, California);  Marco Fiorentino (Milpitas, California)
ABSTRACT Techniques and systems for a semiconductor laser, namely a grating-coupled surface-emitting (GCSE) comb laser, having thermal management for facilitating dissipation of heat, integrated thereon. The thermal management is structured in manner that prevents deformation or damage to the GCSE laser chips included in the semiconductor laser implementation. The disclosed thermal management elements integrated in the laser can include: heat sinks; support bars; solder joints; thermal interface material (TIM); silicon vias (TSV); and terminal conductive sheets. Support bars, for example, having the GCSE laser chip positioned between the bars and having a height that is higher than a thickness of the GCSE laser chip. Accordingly, the heat sink can be placed on top of the support bars such that heat is dissipated from the GCSE laser chip, and the heat sink is separated from directed contact with the GCSE laser chip due to the height of the support bars.
FILED Tuesday, September 08, 2020
APPL NO 17/015001
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/0085 (20130101)
H01S 5/187 (20130101)
H01S 5/0237 (20210101)
H01S 5/0239 (20210101)
H01S 5/02469 (20130101) Original (OR) Class
H01S 5/02476 (20130101)
H01S 5/4025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11875272 Kim et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Non-Profit Organization (NPO)
Semiconductor Research Corporation (SRC)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Hyung-il Kim (Minneapolis, Minnesota);  Ibrahim Ahmed (Minneapolis, Minnesota);  Po-wei Chiu (Minneapolis, Minnesota)
ABSTRACT Compute engine circuitry configured to represent a spin network mapping of a graph representing a combinatorial optimization problem includes a plurality of ring oscillator cells, each of which includes a ring oscillator having an oscillator output, at least one coupling block, and a read block. Each coupling block connects the ring oscillator of the cell to the ring oscillator of one of a plurality of neighboring cells to form a coupled ring oscillator. The read block generates a state output for each coupled ring oscillator that indicates whether the coupled ring oscillator is in one of a same-phase state, in which the connected ring oscillators oscillate in phase with each other, and an opposite-phase state, in which the connected ring oscillators oscillate in an opposite phase from each other. A controller is configured to output a total energy of the mapping based on the state outputs.
FILED Friday, March 26, 2021
APPL NO 17/213396
ART UNIT 2849 — AI & Simulation/Modeling
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Electric Digital Data Processing
G06F 17/10 (20130101)
G06F 17/11 (20130101)

Computer Systems Based on Specific Computational Models
G06N 5/01 (20230101) Original (OR) Class
G06N 5/04 (20130101)
G06N 7/01 (20230101)
G06N 7/08 (20130101)
G06N 10/00 (20190101)

Pulse Technique
H03K 3/0315 (20130101)
H03K 5/19 (20130101)
H03K 19/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 11872092 Yuan
FUNDED BY
U.S. State Government
State of Texas
Cancer Prevention and Research Institute of Texas (TX-CPRIT)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Baohong Yuan (Arlington, Texas)
ABSTRACT A tissue implantation device comprises a capsule; and a population of ultrasound-switchable fluorophores incorporated in the capsule. A method of imaging a tissue implantation device in a biological environment comprises disposing the tissue implantation device in a biological environment, the population of ultrasound-switchable fluorophores having a switching threshold in the biological environment; exposing the biological environment to an ultrasound beam to form an activation region within the biological environment; switching the ultrasound-switchable fluorophores in the activation region from an off state to an on state; exciting the ultrasound-switchable fluorophores in the activation region with a beam of electromagnetic radiation; and detecting light emitted by the ultrasound-switchable fluorophores.
FILED Wednesday, November 11, 2020
APPL NO 17/095121
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0071 (20130101)
A61B 8/481 (20130101)
A61B 90/39 (20160201) Original (OR) Class
A61B 2090/3908 (20160201)
A61B 2090/3941 (20160201)
A61B 2090/3954 (20160201)
A61B 2090/3979 (20160201)

Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0089 (20130101)
A61K 49/223 (20130101)
A61K 49/225 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11875921 Lyon et al.
FUNDED BY
APPLICANT(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Bradley J. Lyon (Hoffman Estates, Illinois);  Nana Kim (Redondo Beach, California);  Hsiao-Hu Peng (Rancho Palos Verdes, California);  John A. Starkovich (Redondo Beach, California);  Edward M. Silverman (Encino, California)
ABSTRACT A carbon nanotube (CNT) cable includes: a pair of plated twisted wires, each wire comprising one or more sub-cores, at least one sub-core comprising CNT yarn; a dielectric surrounding the plated twisted wires; and an electrical layer surrounding the dielectric, the electrical layer configured to shield the CNT cable. A method for making a CNT cable includes: controlling a deposition rate, depositing plating so as to surround a pair of wires, each wire comprising one or more sub-cores, at least one sub-core comprising CNT yarn; twisting the plated wires together; and surrounding the plated twisted wires with an electrical layer configured to shield the plated twisted wires, thereby creating the CNT cable.
FILED Tuesday, September 25, 2018
APPL NO 16/140811
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/168 (20170801)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/38 (20130101)
C25D 5/54 (20130101)
C25D 7/0607 (20130101)

Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/04 (20130101)
H01B 7/18 (20130101) Original (OR) Class
H01B 7/0216 (20130101)
H01B 11/002 (20130101)
H01B 11/20 (20130101)
H01B 13/06 (20130101)
H01B 13/0207 (20130101)
H01B 13/222 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, January 16, 2024.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240116.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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