FedInvent™ Patents
Patent Details for Tuesday, February 13, 2024
This page was updated on Thursday, February 15, 2024 at 05:51 PM GMT
Department of Health and Human Services (HHS)
| US 11896005 | Woods et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ossium Health, Inc. (San Francisco, California) |
| ASSIGNEE(S) | Ossium Health, Inc. (San Francisco, California) |
| INVENTOR(S) | Erik J. Woods (Carmel, Indiana); Brian H. Johnstone (Fishers, Indiana) |
| ABSTRACT | The present disclosure relates to, at least, a vacuum-assisted method for infiltrating cadaver bone with a cryoprotectant and a method for rapidly warming the cryopreserved cadaver bone for bone marrow processing. |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/155657 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) A01N 1/0284 (20130101) Original (OR) Class A01N 1/0289 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 5/0663 (20130101) C12N 2509/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896349 | Madabhushi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Nathaniel Braman (Bethel Park, Pennsylvania) |
| ABSTRACT | Embodiments discussed herein facilitate determination of a response to treatment and/or a prognosis for a tumor based at least in part on features of tumor-associated vasculature (TAV). One example embodiment is a method, comprising: accessing a medical imaging scan of a tumor, wherein the tumor is segmented on the medical imaging scan; segmenting tumor-associated vasculature (TAV) associated with the tumor based on the medical imaging scan; extracting one or more features from the TAV; providing the one or more features extracted from the TAV to a trained machine learning model; and receiving, from the machine learning model, one of a predicted response to a treatment for the tumor or a prognosis for the tumor. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116319 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/004 (20130101) A61B 5/08 (20130101) A61B 5/0035 (20130101) A61B 5/02007 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/12 (20170101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20036 (20130101) G06T 2207/20081 (20130101) G06T 2207/30061 (20130101) G06T 2207/30068 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896360 | Fang et al. |
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| FUNDED BY |
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| APPLICANT(S) | LVIS Corporation (Palo Alto, California); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | LVIS Corporation (Palo Alto, California) |
| INVENTOR(S) | Zhongnan Fang (Santa Clara, California); Akshay S. Chaudhari (Stanford, California); Jin Hyung Lee (Palo Alto, California); Brian A. Hargreaves (Stanford, California) |
| ABSTRACT | Systems and methods for generating thin slice images from thick slice images are disclosed herein. In some examples, a deep learning system may calculate a residual from a thick slice image and add the residual to the thick slice image to generate a thin slice image. In some examples, the deep learning system includes a neural network. In some examples, the neural network may include one or more levels, where one or more of the levels include one or more blocks. In some examples, each level includes a convolution block and a non-linear activation function block. The levels of the neural network may be in a cascaded arrangement in some examples. |
| FILED | Tuesday, March 12, 2019 |
| APPL NO | 16/979104 |
| ART UNIT | 2642 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/7267 (20130101) Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) Image Data Processing or Generation, in General G06T 15/00 (20130101) G06T 2207/30004 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896407 | Ma et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jingchen Ma (New Haven, Connecticut); Laurent Dercle (New York, New York); Binsheng Zhao (Forest Hills, New York); Lin Lu (New York, New York); Lawrence H. Schwartz (New York, New York) |
| ABSTRACT | Techniques measuring post contrast phase include collecting 3D medical imagery of a subject after injection with a contrast agent. A first set of slices is obtained in which each includes a first anatomical feature selected from a portal vein, aorta, inferior vena cava, liver, spleen or renal cortex. A second set of slices is obtained in which each includes a different second anatomical feature. A first image region is obtained from the first set and a different second image region from the second set. A trained convolutional neural network is configured to input the first image region to a first plurality of convolutional hidden layers and the second image region to a second plurality of convolutional hidden layers and output from both to a fully connected hidden layer that outputs a post contrast phase. Output data is presented based on the post contrast phase. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/303145 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10081 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30056 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896428 | Long et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | James Long (Durham, North Carolina); Nicholas Bottenus (Durham, North Carolina); Willie J. Long (Durham, North Carolina); Gregg E. Trahey (Durham, North Carolina) |
| ABSTRACT | An ultrasound system is disclosed. Embodiments in accordance with the present invention include a transducer configured to acquire pulse-echo data at each transmit frequency bandwidth of interest. In addition, a bandpass filter is configured to receive a signal of the pulse-echo data, wherein the signal is bandpass-filtered over a plurality of frequencies. Further, a processor is configured to calculate a spatial coherence of the bandpass-filtered signal. The spatial coherence of the signal is calculated in a spatial domain or a frequency domain. The spatial coherence is used to predict target conspicuity. The processor selects a preferred frequency based on and, preferably, to realize, the target conspicuity. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/080467 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/14 (20130101) Original (OR) Class A61B 8/5207 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/8954 (20130101) G01S 15/8959 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896480 | Welham et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Nathan Welham (Madison, Wisconsin); Changying Ling (Madison, Wisconsin) |
| ABSTRACT | An engineered vocal fold mucosa, including an engineered lamina propria layer and an engineered squamous epithelium layer, is disclosed. The engineered lamina propria is made by seeding and culturing human vocal fold fibroblasts within a polymerized collagen scaffold, and the engineered squamous epithelium is made by culturing human vocal fold epithelial cells on the scaffold surface. The resulting engineered vocal fold mucosa is not immunogenic, and is capable of exhibiting the vibratory function and acoustic output of a native vocal fold mucosa. Accordingly, the engineered vocal fold mucosa may be implanted into the larynx to treat voice impairment. |
| FILED | Thursday, December 13, 2018 |
| APPL NO | 16/218667 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/20 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/3804 (20130101) A61L 27/3813 (20130101) A61L 27/3869 (20130101) A61L 27/3873 (20130101) A61L 27/3886 (20130101) A61L 27/3895 (20130101) A61L 2430/00 (20130101) A61L 2430/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0656 (20130101) C12N 5/0688 (20130101) C12N 5/0697 (20130101) C12N 2509/00 (20130101) C12N 2533/54 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896525 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon); BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | David Huang (Portland, Oregon); Gangjun Liu (Portland, Oregon); Jianlong Yang (Portland, Oregon); Stephen Pflugfelder (Houston, Texas) |
| ABSTRACT | Disclosed is a handheld laser probe for laser thermal conjunctivoplasty, the handheld laser comprising: a forceps; and a line focused laser light source coupled to the forceps, wherein the forceps are configured to grasp a conjunctival fold and hold the fold in a light beam of the line focused laser, and wherein the line focused laser beam is configured to uniformly heat the conjunctival fold held in the forceps. Disclosed are systems for laser thermal conjunctivoplasty including the handheld laser. Disclosed are methods of conjunctivoplasty using the handheld laser probe. |
| FILED | Tuesday, February 27, 2018 |
| APPL NO | 16/487629 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/285 (20130101) A61B 18/22 (20130101) A61B 18/203 (20130101) A61B 2017/00973 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/008 (20130101) Original (OR) Class A61F 2009/00853 (20130101) A61F 2009/00865 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896558 | Sanders et al. |
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| FUNDED BY |
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| APPLICANT(S) | Io Therapeutics, Inc. (Spring, Texas); Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Io Therapeutics, Inc. (Spring, Texas); Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Martin E. Sanders (Spring, Texas); Powel H. Brown (Houston, Texas); Cassandra Moyer (Houston, Texas); Abhijit Mazumdar (Houston, Texas) |
| ABSTRACT | The present specification provides improved methods of treating Her2+ cancers in which an RXR agonist and a taxane are administered to a subject having a Her2+ cancer. Thyroid hormone and other anticancer agents may also be administered. Related compositions and combination are also disclosed. |
| FILED | Wednesday, December 07, 2022 |
| APPL NO | 18/076992 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/015 (20130101) Original (OR) Class A61K 31/56 (20130101) A61K 31/192 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896568 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Jianjun Chen (Cincinnati, Ohio); Rui Su (Cincinnati, Ohio) |
| ABSTRACT | Pharmaceutical compositions, kits and methods for treating tumors such as glioma and cancers such as leukemia with (R)-2-hydroxyglutarate (R-2HG) are provided, along with therapeutic regimens including treatment of a patient suffering from glioma or leukemia with a MYC-signaling inhibitor followed by or cotemporaneous with treatment with R-2HG, and optionally other chemotherapeutic agents. |
| FILED | Thursday, October 14, 2021 |
| APPL NO | 17/501692 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/194 (20130101) Original (OR) Class A61K 31/203 (20130101) A61K 31/704 (20130101) A61K 31/7068 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896584 | Lamichhane et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); University of St. Thomas (St. Paul, Minnesota) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSTY (Baltimore, Maryland); UNIVERSITY OF ST. THOMAS (St. Paul, Minnesota) |
| INVENTOR(S) | Gyanu Lamichhane (Towson, Maryland); J. Thomas Ippoliti (St. Paul, Minnesota) |
| ABSTRACT | The present invention is a method of treating or preventing Mycobacterium tuberculosis infection in a subject by administering to the subject an effective amount of oxazolidinone, specifically (N—(((S)-3-(dibenzo[b,e][1,4]dioxin-7-yl)-2-oxooxazolidin-5-yl)methyl)acetamide) or a pharmaceutically acceptable salt, solvate, or stereoisomer thereof. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/060823 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896591 | Hoehn et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia); VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia); NEWSOUTH INNOVATIONS PTY LIMITED (Sydney, Australia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Kyle Hoehn (Charlottesville, Virginia); Webster L. Santos (Blacksburg, Virginia); Elizabeth S. Childress (Christiansburg, Virginia); Yumin Dai (Blacksburg, Virginia); Jacob Murray (Blacksburg, Virginia); Jose Santiago-Rivera (Blacksburg, Virginia) |
| ABSTRACT | This disclosure provides compounds of Formula I, II, and III and pharmaceutically acceptable salts thereof for use as mitochondrial uncouplers, where the variables, e.g. R1-R9, X1, X2, and Y1 are defined in the specification. The disclosure also provides pharmaceutical compositions comprising a compound or pharmaceutically acceptable salt of Formula I, II, or III, alone or in combination with another active compound. Compounds and compositions of Formula I, II, and III are useful for treating or preventing certain conditions such as obesity, type II diabetes, fatty liver disease, insulin resistance, Parkinson's disease, ischemia reperfusion injury, heart failure, non-alcoholic fatty liver disease (NALFD), and non-alcoholic steatohepatitis (NASH). Compounds of Formula I, II, and III are also useful for regulating glucose homeostatis and insulin action. |
| FILED | Tuesday, May 22, 2018 |
| APPL NO | 16/615567 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4965 (20130101) A61K 31/4985 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) Heterocyclic Compounds C07D 241/20 (20130101) C07D 487/04 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896619 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jianzhu Chen (Lexington, Massachusetts); Guozhu Xie (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure relates to compounds (e.g., antibodies, antigen-binding fragments thereof, bispecific molecules, or chimeric antigen receptor polypeptides) that bind to a neoepitope of mutant nucleophosmin (NPM1c) in complex with, or presented by, a class I major histocompatibility complex (MHC class I) protein, or cells expressing such compounds, and their use in methods for treating, or ameliorating one or more symptoms of, cancer. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144834 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/3061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896626 | Hasty et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jeff Hasty (Encinitas, California); Michael Julius Liao (San Diego, California); Muhammad Omar Din (San Diego, California) |
| ABSTRACT | Provided herein are multi-strain population control systems, methods, kits, and compositions. Also provided are methods, systems, kits, and compositions for culturing bacterial cells in multi-strain ecosystems, and temporally arranged multi-strain ecosystems or cultures using a synchronized lysis circuit in combination with multiple toxin/antitoxin systems to cycle continuously over a long period of time. |
| FILED | Friday, June 07, 2019 |
| APPL NO | 16/972405 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Original (OR) Class A61K 2035/115 (20130101) Peptides C07K 14/245 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896629 | Mazmanian et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Sarkis K Mazmanian (Porter Ranch, California); Paul H Patterson (Altadena, California); Janet Chow (Alhambra, California); Elaine Hsiao (Rowland Heights, California); Sara W McBride (Pasadena, California) |
| ABSTRACT | Provided is a method and a composition for improving behavioral performance in an individual comprising identifying an individual in need of treatment, and providing such an individual a composition comprising bacteria within the genus Bacteroides. |
| FILED | Wednesday, July 22, 2020 |
| APPL NO | 16/935837 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/741 (20130101) Original (OR) Class A61K 2035/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896633 | Belcher et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Angela M. Belcher (Lexington, Massachusetts); Uyanga Tsedev (Somerville, Massachusetts); Fred Lam (Brookline, Massachusetts) |
| ABSTRACT | Provided are engineered phages populations, which are homogeneous in length, as well as methods of making and methods of using such phages. Also provided are engineered chlorotoxin-phages as well as their methods of making and using. The disclosed homogeneous phage populations and chlorotoxin-phages may be used, for example, for treating and/or imaging tumors, such as central nervous system tumors. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/208256 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/76 (20130101) Original (OR) Class A61K 47/6415 (20170801) A61K 47/6901 (20170801) A61K 49/0021 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/70 (20130101) C12N 15/861 (20130101) C12N 2795/14121 (20130101) C12N 2795/14122 (20130101) C12N 2795/14131 (20130101) C12N 2795/14132 (20130101) C12N 2800/202 (20130101) C12N 2810/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896639 | Cheng |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Yung-Chi Cheng (New Haven, Connecticut) |
| ABSTRACT | The invention relates to methods of evaluating the quality of a batch of an herbal composition, the method comprising subjecting a test batch of the herbal composition to one or more biological analysis methods and comparing the results derived from the test batch to the results of a known batch of herbal composition which has a known in vivo effect. |
| FILED | Tuesday, November 22, 2022 |
| APPL NO | 18/058042 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 36/65 (20130101) A61K 36/484 (20130101) A61K 36/539 (20130101) Original (OR) Class A61K 36/725 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896644 | Woo et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Jung A. Woo (Wesley Chapel, Florida); Stephen Bryant Liggett (Treasure Island, Florida); David E. Kang (Wesley Chapel, Florida); Yu Chen (Tampa, Florida); Eric Lewandowski (Tampa, Florida) |
| ABSTRACT | As disclosed herein, β-arrestin1 and β-arrestin2 levels are highly elevated in brains of FTLD-tau patients suggesting that both β-arrestin1 and β-arrestin2 are elevated in the brains of patients with AD and FLTD. The current work also shows that when β-arrestin2 is overexpressed, tau levels become elevated. The data indicate that β-arrestin2 reduces tau clearance by impairing p62-mediated autophagy, a role carried out by the oligomerized form of β-arrestin2. Therefore, disclosed herein are β-arrestin oligomerization inhibitors that can be used to prevent β-arrestin oligomerization and therefore the accumulation of tau in cells, i.e. tauopathy. Also disclosed are methods of treating a tauopathy in a subject that involve administering to the subject a therapeutically effective amount of a β-arrestin oligomerization inhibitor disclosed herein. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/798041 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/437 (20130101) A61K 31/496 (20130101) A61K 38/1709 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896658 | Oomens |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents for Oklahoma State University (Stillwater, Oklahoma) |
| ASSIGNEE(S) | Board of Regents for Oklahoma State University (Stillwater, Oklahoma) |
| INVENTOR(S) | Antonius G. P. Oomens (Stillwater, Oklahoma) |
| ABSTRACT | Recombinant, live, attenuated viruses of the Pneumoviridae family are disclosed that include a baculovirus GP64 envelope glycoprotein or variant or fragment thereof and a respiratory syncytial virus (RSV) F protein variant or fragment thereof. Also disclosed are polynucleotides encoding the virus as well as pharmaceutical compositions and vaccines containing the virus. In addition, methods of producing and using each of the above compositions are also disclosed. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/848637 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/575 (20130101) A61K 2039/5254 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/14052 (20130101) C12N 2760/18534 (20130101) C12N 2760/18562 (20130101) C12N 2760/18571 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896661 | Wan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mississippi State University (Starkville, Mississippi) |
| ASSIGNEE(S) | Mississippi State University (Starkville, Mississippi) |
| INVENTOR(S) | Xiu-Feng Wan (Starkville, Mississippi); Feng Wang (Starkville, Mississippi) |
| ABSTRACT | A composition for increasing vaccine yields due to increased virus growth in mutation comprising a vaccine strain bearing the Y161F mutation in hemagglutinin (HA). Y161F in HA increases HA thermostability without changing its original antigenic properties and enhances its binding affinity in the vaccine production platforms used in influenza vaccine manufacturing. A method for optimizing preparation of influenza vaccine seed strains which can further lower the cost of vaccines and increase profits for the vaccine companies, and also maintain antigenic stability during vaccine deliveries. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 16/608662 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896669 | Khvorova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Matthew Hassler (Worcester, Massachusetts); Julia Alterman (Worcester, Massachusetts); Bruno Miguel da Cruz Godinho (Worcester, Massachusetts) |
| ABSTRACT | Provided herein are branched oligonucleotides exhibiting efficient and specific tissue distribution, cellular uptake, minimum immune response and off-target effects, without formulation. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/012787 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7084 (20130101) A61K 47/26 (20130101) Original (OR) Class A61K 47/55 (20170801) A61K 47/549 (20170801) A61K 47/551 (20170801) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/08 (20130101) C07H 21/04 (20130101) C07H 99/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/52 (20130101) C12N 2310/3513 (20130101) C12N 2310/3515 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896673 | Gu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Zhen Gu (Raleigh, North Carolina); Chao Wang (Raleigh, North Carolina) |
| ABSTRACT | Disclosed herein is a glucose-responsive insulin delivery system based on the interaction between the glucose-modified insulin and glucose transporters (GLUTs) on erythrocytes (or red blood cells, RBCs). After being conjugated with glucose, insulin can efficiently bind to RBC membranes. The binding is reversible in the setting of hyperglycemia, resulting in fast release of insulin and subsequent drop of blood glucose (BG) level in vivo. In some embodiments, the delivery vehicle can include: 1) intravenously injectable polymeric nanoparticles (˜100 nm in diameter) coated with RBC membrane and loaded with glucose-modified insulin and/or 2) painless microneedle (MN) patches loaded with the complex of GLUT and glucose-modified insulin. |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/188583 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) A61K 35/18 (20130101) A61K 38/28 (20130101) A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/549 (20170801) Original (OR) Class A61K 47/6937 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 13/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896676 | Steinmetz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California); Sourabh Shukla (Cleveland, Ohio) |
| ABSTRACT | A pepino mosaic virus (PepMV) carrier comprising a PepMV particle that has been modified to carry an imaging agent or anticancer agent is described. The PepMV carrier can be used in a method of targeting cancer cells and tissue by administering it to a subject. Cancer tissue targeted by the PepMV carrier can be imaged using an imaging agent, or treated using an anticancer agent. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988210 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 47/6901 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896678 | Goldstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Jonathan Goldstein (Cambridge, Massachusetts); Matthew Meyerson (Boston, Massachusetts); Craig Strathdee (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides compositions and methods for the treatment of PPARG activated cancer. For example, the present disclosure provides PPARG signaling modulators for the treatment of bladder cancer. In particular, therapeutic and/or prophylactic compositions and uses of PPARG inverse-agonists are described. |
| FILED | Wednesday, March 28, 2018 |
| APPL NO | 16/498860 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 45/06 (20130101) A61K 48/0025 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/70567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896679 | Jaskula-Ranga et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Vinod Jaskula-Ranga (Cambridge, Massachusetts); Donald Zack (Baltimore, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides compositions and methods for the expression of CRISPR guide RNAs using the H1 promoter. In particular, compositions and methods are provided for the use of the H1 promoter to express CRISPR guide RNA (gRNA) with altered specificity of the 5′ nucleotide, as well as use of the H1 promoter sequence as a bidirectional promoter to express Cas9 nuclease and the gRNA simultaneously. Compositions and methods are also provided for the expression and regulation of gRNA expression in vivo through the use of RNA ribozymes and regulatable aptazymes. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 16/851636 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) Original (OR) Class Peptides C07K 2319/10 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/907 (20130101) C12N 15/1138 (20130101) C12N 15/8616 (20130101) C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2330/51 (20130101) C12N 2750/14133 (20130101) C12N 2750/14143 (20130101) C12N 2830/85 (20130101) C12N 2830/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896686 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Yang Deng (Edison, New Jersey); Asiri Ediriwickrema (Cary, North Carolina); William M. Saltzman (New Haven, Connecticut) |
| ABSTRACT | Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polyglycerol (HPG). The HPG coating can be modified to adjust the properties of the particles. Unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption and increase circulation in the blood. The hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups and adhere the particles to tissue, cells, or extracellular materials, such as proteins. |
| FILED | Thursday, June 16, 2022 |
| APPL NO | 17/842376 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/90 (20130101) A61K 8/0241 (20130101) Original (OR) Class A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/1647 (20130101) A61K 9/5031 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) A61K 31/427 (20130101) A61K 31/4178 (20130101) A61K 31/4745 (20130101) A61K 47/34 (20130101) A61K 2800/412 (20130101) A61K 2800/413 (20130101) A61K 2800/624 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101) Acyclic or Carbocyclic Compounds C07C 59/06 (20130101) C07C 59/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896713 | Minko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Tamara Minko (East Brunswick, New Jersey); Olga B. Garbuzenko (Skillman, New Jersey) |
| ABSTRACT | A nanocarrier containing a combination of bioactive agents is provided. The nanocarrier allows for targeted delivery of the agents to cancer cells with minimized side effect. |
| FILED | Friday, October 22, 2021 |
| APPL NO | 17/508535 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0078 (20130101) A61K 9/1272 (20130101) Original (OR) Class A61K 31/277 (20130101) A61K 31/282 (20130101) A61K 31/337 (20130101) A61K 31/365 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/553 (20130101) A61K 31/704 (20130101) A61K 31/5377 (20130101) A61K 33/243 (20190101) A61K 47/64 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896724 | Rege et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Kaushal Rege (Chandler, Arizona); Deepanjan Ghosh (Tempe, Arizona) |
| ABSTRACT | A wound dressing includes: a structural material formed into a dressing; at least one immunomodulatory agent associated with the dressing; and a growth factor associated with the dressing. A wound dressing kit includes: a structural material formed into a wound dressing; an immunomodulatory agent; and a growth factor composition, wherein the structural material contains the immunomodulatory agent and/or the immunomodulatory agent in a separate composition. A method of treating a wound in a tissue includes: applying an immunomodulatory agent to the wound; applying a wound dressing to the wound; and allowing the wound to heal with the immunomodulatory agent and wound dressing. The application of a growth factor can be before, during and/or after applying the wound dressing to the wound. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/065283 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/7007 (20130101) A61K 31/417 (20130101) A61K 33/242 (20190101) A61K 38/39 (20130101) A61K 38/1825 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/18 (20130101) A61L 15/20 (20130101) A61L 15/32 (20130101) A61L 15/44 (20130101) Original (OR) Class A61L 26/0004 (20130101) A61L 26/008 (20130101) A61L 26/0066 (20130101) A61L 26/0095 (20130101) A61L 2300/45 (20130101) A61L 2300/102 (20130101) A61L 2300/414 (20130101) A61L 2300/426 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/067 (20210801) A61N 5/0616 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896748 | Chait et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts); Analiza, Inc. (Cleveland, Ohio); Medical University of Graz (Graz, Austria) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Yossi Chait (Longmeadow, Massachusetts); Joseph Horowitz (Amherst, Massachusetts); Christopher V. Hollot (East Hampton, Massachusetts); Hamed Samandari (Mason, Ohio); Michael J. Germain (Hampden, Massachusetts); Daniel Schneditz (Graz, Austria) |
| ABSTRACT | Absolute blood volume in dialysis patients is a useful patient attribute to know for dialysis treatment, diagnosis, adjustments, etc. In some cases, it is difficult or impossible to directly determine absolute blood volume. Estimating absolute blood volume may be used to overcome the inability to directly determine the absolute blood volume. Estimating absolute blood volume may include obtaining a series of measurements of hemoconcentration of a patient over a time period, and estimating parameters for a physiological model based on the series of measurements. The absolute blood volume of the patient may be determined using the physiological model. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 16/617904 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0275 (20130101) A61B 5/02028 (20130101) A61B 5/6866 (20130101) A61B 5/14535 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/267 (20140204) A61M 1/361 (20140204) A61M 1/1613 (20140204) Original (OR) Class A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/3389 (20130101) A61M 2230/20 (20130101) A61M 2230/207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896800 | Gu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| INVENTOR(S) | Zhen Gu (Raleigh, North Carolina); Chao Wang (Raleigh, North Carolina); Yanqi Ye (Raleigh, North Carolina) |
| ABSTRACT | Disclosed herein are self-degradable microneedle devices for the controlled-release of an immunotherapeutic agent. Also disclosed are methods for treating a disease (for example, cancer) using a self-degradable microneedle patch for the sustained delivery of an immunotherapeutic agent (for example, a PD1 antibody). |
| FILED | Wednesday, March 01, 2017 |
| APPL NO | 16/081188 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/41 (20130101) A61B 5/055 (20130101) A61B 5/1486 (20130101) A61B 5/150022 (20130101) A61B 5/150969 (20130101) A61B 5/150984 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) A61K 31/728 (20130101) A61K 31/734 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/158 (20130101) Original (OR) Class A61M 5/168 (20130101) A61M 2037/0046 (20130101) A61M 2037/0061 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2803 (20130101) C07K 16/2896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896853 | Khokhlova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Vera Khokhlova (Seattle, Washington); Pavel Rosnitskiy (Seattle, Washington); Petr V. Yuldashev (Moscow, Russian Federation); Tatiana D. Khokhlova (Seattle, Washington); Oleg A. Sapozhnikov (Seattle, Washington); George R. Schade (Seattle, Washington) |
| ABSTRACT | Transrectal ultrasound probe for boiling histotripsy ablation of prostate are presented herein. In one embodiment, a method for a transrectal ultrasound treatment uses high intensity focused ultrasound (HIFU). The method includes: generating a boiling histotripsy (BH) therapy ultrasound by a therapy transducer in a frequency range of 1 MHz to 2.8 MHz and a surface intensity range of 10 W/cm2 to 80 W/cm2. The therapy transducer may be about 50 mm long and about 35 mm wide. The method also includes applying the therapy ultrasound by directing ultrasound pulses having ultrasound shock waves to a target tissue at a focal depth of 2.5 cm to 5.5 cm; generating at least one μm-scale vapor bubble at a target region; growing the at least one vapor bubble to at least one mm-scale bubble; and mechanically disintegrating a surrounding tissue by interactions between mm-scale bubbles and the ultrasound shock waves within a pulse. |
| FILED | Monday, May 11, 2020 |
| APPL NO | 16/871980 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/12 (20130101) A61B 8/445 (20130101) A61B 2017/00274 (20130101) A61B 2017/320069 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/022 (20130101) Original (OR) Class A61N 2007/0039 (20130101) A61N 2007/0052 (20130101) A61N 2007/0078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896974 | Burns et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Mark A. Burns (Ann Arbor, Michigan); Alyse D. Krausz (Ann Arbor, Michigan); Sarah Elizabeth Mena (Ann Arbor, Michigan); Martin Patrick De Beer (Ann Arbor, Michigan); Kevin R. Ward (Superior Township, Michigan); Frederick Korley (Ann Arbor, Michigan) |
| ABSTRACT | A microfluidic device system includes a channel having an entrance and an exit, a height at the entrance being greater than a height at the exit. The height of the channel may decrease continuously from the height at the entrance to the height at the exit. Cells or particles or beads traveling through the channel become trapped based on their size and/or deformability. A visual sensor captures images of the trapped cells or particles or beads, and image software analyzes the captured images to provide size and/or deformability and/or fluorescence information. A method of fabricating such a microfluidic device includes introducing a glass wafer to an etching solution at a specific rate such that a first end of the glass wafer is etched longer than other portions of the glass wafer. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859400 |
| ART UNIT | 1758 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 2200/12 (20130101) B01L 2200/0668 (20130101) B01L 2300/0627 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 15/1475 (20130101) G01N 21/6428 (20130101) G01N 33/6803 (20130101) G01N 33/54366 (20130101) G01N 2015/1493 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897775 | Handa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Hitesh Handa (Athens, Georgia); Marcus Goudie (Athens, Georgia); Jitendra Pant (Athens, Georgia); Bryan Grommersch (Alpharetta, Georgia); Sean Hopkins (Athens, Georgia) |
| ABSTRACT | Nitric oxide-releasing materials, methods of making nitric oxide-releasing materials, and uses of nitric oxide-releasing materials are provided. The nitric oxide-releasing materials include a mesoporous silica core and an outer surface having a plurality of nitric oxide donors. In an exemplary aspects, the nitric oxide-releasing material includes a mesoporous diatomaceous earth core, and an outer surface having a plurality of S-nitroso-N-acetyl-penicillamine groups covalently attached thereto. Uses of the nitric oxide-releasing materials can include coatings for medical devices such as catheters, grafts, and stents; wound gauzes; acne medications; and antiseptic mouthwashes; among others. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399634 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/28 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/306 (20130101) A61L 27/3637 (20130101) A61L 29/08 (20130101) A61L 29/16 (20130101) A61L 29/106 (20130101) A61L 29/146 (20130101) A61L 31/08 (20130101) A61L 31/16 (20130101) A61L 31/088 (20130101) A61L 31/146 (20130101) A61L 2300/114 (20130101) A61L 2420/04 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/149 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/61 (20130101) C01P 2006/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897845 | Maloney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); VANDERBILT UNIVERSITY (Nashville, Tennessee); The UAB Research Foundation (Birmingham, Alabama); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); VANDERBILT UNIVERSITY (Nashville, Tennessee); THE UAB RESEARCH FOUNDATION (Birmingham, Alabama); THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | David J. Maloney (Point of Rocks, Maryland); Alex Gregory Waterson (Nashville, Tennessee); Ganesh Rai Bantukallu (Arlington, Virginia); Kyle Ryan Brimacombe (Bethesda, Maryland); Plamen Christov (Nashville, Tennessee); Chi V. Dang (Penn Valley, Pennsylvania); Victor Darley-Usmar (Birmingham, Alabama); Xin Hu (Frederick, Maryland); Ajit Jadhav (Chantilly, Virginia); Somnath Jana (Nashville, Tennessee); Kwangho Kim (Nashville, Tennessee); Jennifer L. Kouznetsova (Silver Spring, Maryland); William J. Moore (Hagerstown, Maryland); Bryan T. Mott (College Park, Maryland); Leonard M. Neckers (Bethesda, Maryland); Anton Simeonov (Bethesda, Maryland); Gary Allen Sulikowski (Nashville, Tennessee); Daniel Jason Urban (Rockville, Maryland); Shyh Ming Yang (Doylestown, Pennsylvania) |
| ABSTRACT | Provided is a compound of formula (I) in which Ar1, R1, U, V, W, X, and p are as described herein. Also provided are methods of using a compound of formula (I), including a method of treating cancer, a method of treating a patient with cancer cells resistant to an anti-cancer agent, and a method of inhibiting lactate dehydrogenase A (LDHA) and/or lactate dehydrogenase B (LDHB) activity in a cell. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/572359 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) A61K 31/422 (20130101) A61K 31/427 (20130101) A61K 31/437 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4155 (20130101) A61K 31/4178 (20130101) A61K 31/4439 (20130101) A61K 31/5355 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 231/20 (20130101) Original (OR) Class C07D 231/38 (20130101) C07D 401/04 (20130101) C07D 403/04 (20130101) C07D 403/06 (20130101) C07D 409/04 (20130101) C07D 413/04 (20130101) C07D 417/04 (20130101) C07D 417/14 (20130101) C07D 471/04 (20130101) C07D 495/04 (20130101) C07D 495/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897865 | Ogasawara et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Daisuke Ogasawara (La Jolla, California); Taka-Aki Ichu (La Jolla, California); Jonathan Hulce (La Jolla, California); Benjamin F. Cravatt (La Jolla, California) |
| ABSTRACT | Provided herein are compounds and compositions useful as modulators of ABHD12. Furthermore, the subject compounds and compositions are useful as immunotherapies in treating, for instance, cancer or infectious diseases. |
| FILED | Tuesday, May 14, 2019 |
| APPL NO | 17/055081 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 471/04 (20130101) C07D 471/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897870 | Canney et al. |
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| FUNDED BY |
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| APPLICANT(S) | Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Temple University-Of The Commonwealth System Higher Education (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Daniel J. Canney (Ambler, Pennsylvania); Benjamin E. Blass (Eagleville, Pennsylvania); Rong Gao (Eugene, Oregon); Magid Abou-Gharbia (Exton, Pennsylvania) |
| ABSTRACT | Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 16/861075 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 307/33 (20130101) C07D 307/94 (20130101) C07D 405/06 (20130101) C07D 405/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897873 | Roberts et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California); BlackThorn Therapeutics, Inc. (San Francisco, California) |
| ASSIGNEE(S) | BLACKTHORN THERAPEUTICS, INC. (San Francisco, California); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Edward Roberts (Fallbrook, California); Miguel A. Guerrero (San Diego, California); Mariangela Urbano (Del Mar, California); Hugh Rosen (La Jolla, California); Robert M. Jones (South San Francisco, California); Candace Mae Laxamana (South San Francisco, California); Xianrui Zhao (South San Francisco, California); Eric Douglas Turtle (Belmont, California) |
| ABSTRACT | Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt thereof: wherein X, Y, R1, R2, R4, R5, R6, R7, R8 and R11 are as defined herein. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/390531 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/06 (20180101) Heterocyclic Compounds C07D 413/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897875 | Thompson et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Scott Thompson (Baltimore, Maryland); Adam Van Dyke (Baltimore, Maryland); Craig Thomas (Gaithersburg, Maryland); Patrick Morris (Laurel, Maryland) |
| ABSTRACT | The present invention relates to novel alpha5 subunit-selective negative allosteric modulators of GABAA receptors that have been deuterated to improve their medicinal properties by prolonging their half-lives, rendering them useful as fast-acting pharmaceutical treatments for depression related disorders. |
| FILED | Tuesday, August 09, 2022 |
| APPL NO | 17/883734 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/24 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Heterocyclic Compounds C07D 261/08 (20130101) C07D 413/12 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897886 | Gangjee |
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| FUNDED BY |
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| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Duquesne University of The Holy Spirit (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania) |
| ABSTRACT | A compound of Formula II, or optionally a salt or a hydrate of the compound of Formula II is provided: wherein R1 is selected from the group consisting of a hydrogen, an alkyl group having from one to six carbon atoms, an aryl group, and a heteroaryl group; R2 is selected from the group consisting of an alkyl group having from one to six carbon atoms, a hydrogen, a NRaRb group wherein Ra is either a hydrogen or an alkyl group having from one to six carbon atoms and Rb is either a hydrogen or an alkyl group having from one to six carbon atoms, an aryl group, a heteroaryl group, and a halogen; R is an alkyl group having from one to six carbon atoms; and Ar is selected from the group consisting of an alkyl group having from one to six carbon atoms, a substituted aryl, and a substituted heteroaryl. |
| FILED | Monday, November 02, 2020 |
| APPL NO | 16/949519 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897905 | Johnson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeremiah A. Johnson (Boston, Massachusetts); Peyton Shieh (Cambridge, Massachusetts); Wenxu Zhang (Belmont, Massachusetts) |
| ABSTRACT | The present disclosure provides cyclic silyl ethers of the formula: and salts thereof. The cyclic silyl ethers may be useful as monomers for preparing polymers. Also described herein are polymers prepared by polymerizing a cyclic silyl ether and optionally one or more additional monomers. The polymers may be degradable (e.g., biodegradable). One or more O—Si bonds of the polymers may be the degradation sites. Also described herein are compositions and kits including the cyclic silyl ethers or polymers; methods of preparing the polymers; and methods of using the polymers, compositions, and kits. |
| FILED | Wednesday, March 17, 2021 |
| APPL NO | 17/204462 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/787 (20130101) A61K 45/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0834 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/06 (20130101) C08G 2261/126 (20130101) C08G 2261/418 (20130101) C08G 2261/3324 (20130101) Compositions of Macromolecular Compounds C08L 79/08 (20130101) C08L 83/04 (20130101) C08L 2201/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897919 | Robinson |
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| FUNDED BY |
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| APPLICANT(S) | GeoVax, Inc. (Smyrna, Georgia) |
| ASSIGNEE(S) | Geovax, Inc. (Smyrna, Georgia) |
| INVENTOR(S) | Harriet Robinson (Palo Alto, California) |
| ABSTRACT | Compositions and methods of use are provided to boost a primed immune response to HIV. More specifically, the present invention relates to vaccine compositions comprising an HIV-protein boost or an MVA-expressed Env protein and methods of use. Exemplary HIV proteins for protein boosts include proteins such as gp120 proteins B.63521Δ11mutC and full-length single chain (FLSC), which has been modified to stabilize a CD4-induced Env structure. Exemplary MVAs expressing secreted Methods of administration and dosing regimens are also provided. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 17/409574 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Peptides C07K 14/161 (20130101) C07K 14/162 (20130101) Original (OR) Class C07K 14/163 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/8636 (20130101) C12N 2710/24143 (20130101) C12N 2740/16023 (20130101) C12N 2740/16134 (20130101) C12N 2740/16234 (20130101) C12N 2740/16334 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897921 | Ichtchenko et al. |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Konstantin Ichtchenko (Brooklyn, New York); Edwin Vazquez-Cintron (New York, New York); Philip A. Band (West Orange, New Jersey); Timothy J. Cardozo (New York, New York) |
| ABSTRACT | The present invention is directed to a fusion protein comprising a light chain region of a Clostridial neurotoxin and a heavy chain region of a Clostridial neurotoxin, where the light and heavy chain regions are linked by a disulfide bond. The fusion protein also has a single chain antibody positioned upstream of the light chain region, where the single chain antibody possesses antigen-binding activity. Also disclosed are therapeutic agents, treatment methods, propeptide fusions, isolated nucleic acid molecules, expression systems, host cells, and methods of expressing fusion proteins. |
| FILED | Wednesday, December 09, 2015 |
| APPL NO | 14/964146 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 14/33 (20130101) Original (OR) Class C07K 16/1282 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/21 (20130101) C07K 2319/22 (20130101) C07K 2319/41 (20130101) C07K 2319/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897922 | Reed et al. |
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| FUNDED BY |
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| APPLICANT(S) | ACCESS TO ADVANCED HEALTH INSTITUTE (Seattle, Washington) |
| ASSIGNEE(S) | ACCESS TO ADVANCED HEALTH INSTITUTE (Seattle, Washington) |
| INVENTOR(S) | Steven G. Reed (Bellevue, Washington); Rhea N. Coler (Seattle, Washington); Gregory C. Ireton (Seattle, Washington); Sylvie Bertholet (Gaithersburg, Maryland) |
| ABSTRACT | The present invention relates to compositions and fusion proteins containing at least two Mycobacterium sp.) antigens, and polynucleotides encoding such compositions and fusion proteins. The invention also relates to methods for their use in the treatment, prevention and/or diagnosis of tuberculosis infections. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 17/367812 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 2039/55561 (20130101) Peptides C07K 14/35 (20130101) Original (OR) Class C07K 14/285 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/5695 (20130101) G01N 2469/20 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897929 | Krupnick et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Alexander Sasha Krupnick (St. Louis, Missouri); Daved Henry Fremont (St. Louis, Missouri); Eric Reed Lazear (St. Louis, Missouri); John Westwick (Houston, Texas) |
| ABSTRACT | The present disclosure encompasses compositions and methods for targeted cytokine delivery. The compositions disclosed herein comprise a cytokine linked to an NKG2D ligand or PD1 ligand and may improve immunotherapy by limiting side effects associated with immunotherapy. The present disclosure also encompasses compositions and methods for recruiting cytotoxic lymphocytes to target cells using NKG2D receptor ligands or PD1 ligands. The compositions disclosed herein comprise a NKG2D receptor ligand and a targeting molecule and may improve immunotherapy by limiting side effects associated with immunotherapy. |
| FILED | Friday, April 23, 2021 |
| APPL NO | 17/238995 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/6849 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/52 (20130101) C07K 14/55 (20130101) Original (OR) Class C07K 14/545 (20130101) C07K 14/5418 (20130101) C07K 14/5443 (20130101) C07K 14/70596 (20130101) C07K 16/2851 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897931 | Burnett, Jr. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | John C. Burnett, Jr. (Rochester, Minnesota) |
| ABSTRACT | Analogues of an alternatively spliced form of atrial natriuretic peptide (MANP) that exhibit pGC-A gain of function and can be used to treat cardiorenal and metabolic disease are described herein. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/359088 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/12 (20180101) A61P 13/12 (20180101) Peptides C07K 14/58 (20130101) Original (OR) Class C07K 14/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897932 | Roybal et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kole T. Roybal (San Francisco, California); Raymond Liu (San Francisco, California); Iowis Zhu (San Francisco, California) |
| ABSTRACT | The present disclosure generally relates to, among other things, a new class of receptors engineered to modulate transcriptional regulation in a ligand-dependent manner. Particularly, the new receptors, even though derived from Notch, do not require the Notch negative regulatory regions previously believed to be essential for the functioning of the receptors. The disclosure also provides compositions and methods useful for producing such receptors, nucleic acids encoding same, host cells genetically modified with the nucleic acids, as well as methods for modulating an activity of a cell and/or for the treatment of various health conditions or diseases, such as cancers. |
| FILED | Tuesday, March 30, 2021 |
| APPL NO | 17/217635 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/09 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897933 | Tran et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Eric Tran (Portland, Oregon); Yong-Chen Lu (Rockville, Maryland); Anna Pasetto (Stockholm, Sweden); Paul F. Robbins (Chevy Chase, Maryland); Steven A. Rosenberg (Potomac, Maryland); Zhili Zheng (Gaithersburg, Maryland) |
| ABSTRACT | Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/345390 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/82 (20130101) C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 2015/8518 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 2333/7051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897938 | Spencer et al. |
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| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | EMORY UNIVERSITY (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| INVENTOR(S) | H. Trent Spencer (Marietta, Georgia); Christopher B. Doering (Atlanta, Georgia); Philip M. Zakas (Atlanta, Georgia); Eric Gaucher (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to recombinant or chimeric FVIII proteins, variants, and vectors encoding the proteins containing one or more ancestral mutations. In certain embodiments, one or more protein domains comprise amino acid sequences that are derived from ancestrally reconstructed amino acid sequences. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising the proteins or vectors and related methods of inducing blood clotting. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/355656 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/755 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897939 | Lai et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Samuel Lai (Carrboro, North Carolina); Ying-Ying Wang (San Francisco, California); Arthi Kannan (Morrisville, North Carolina); Kenetta Nunn (Moscow, Idaho); Durai Babu Subramani (Chapel Hill, North Carolina); Richard Cone (Baltimore, Maryland); Bing Yang (Chapel Hill, North Carolina); Justin Mccallen (Greenville, North Carolina) |
| ABSTRACT | The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating virus infection in the respiratory tract and virus transmission through the respiratory tract. In particular, the presently-disclosed subject matter relates to inhibiting and treating virus infection in a subject using compositions and antibodies that trap viruses in mucus of the respiratory tract, thereby inhibiting transport of virus across or through mucus secretions. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/066874 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) A61K 2039/544 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) A61P 31/12 (20180101) A61P 31/14 (20180101) A61P 31/22 (20180101) Peptides C07K 16/10 (20130101) C07K 16/087 (20130101) Original (OR) Class C07K 16/1027 (20130101) C07K 16/1214 (20130101) C07K 2317/13 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/41 (20130101) C07K 2317/54 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897940 | Nussenzweig et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | THE ROCKEFELLER UNIVERSITY (New York, New York); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Michel Nussenzweig (New York, New York); Natalia T. Freund (New York, New York); Pamela J. Bjorkman (Altadena, California); Louise Scharf (Porter Ranch, California) |
| ABSTRACT | This invention relates to broadly neutralizing and potent anti-HIV-1 antibodies, kits, and methods of use thereof. |
| FILED | Wednesday, March 30, 2022 |
| APPL NO | 17/708763 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/21 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/1045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897942 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania); LANKENAU INSTITUTE OF MEDICAL RESEARCH (Wynnewood, Pennsylvania) |
| ASSIGNEE(S) | Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania); LANKENAU INSTITUTE OF MEDICAL RESEARCH (Wynnewood, Pennsylvania) |
| INVENTOR(S) | Cagla Tukel Wilson (Huntingdon Valley, Pennsylvania); Scott Dessain (Wynnewood, Pennsylvania) |
| ABSTRACT | The present invention features compositions comprising an anti-amyloid antibody and methods of treating microbial infection and treating or preventing microbial biofilms using the composition. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 17/058575 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 16/1228 (20130101) C07K 16/1232 (20130101) C07K 16/1235 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897950 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Kebin Liu (Augusta, Georgia); John Klement (Augusta, Georgia); Priscilla S. Redd (Augusta, Georgia) |
| ABSTRACT | Antibodies and antigen binding fragments thereof that immunospecifically bind OPN (OPN) and inhibit OPN activity are provided herein. The disclosed antibodies and antigen binding fragments are useful for modulating signal transduction through OPN proteins. The antibodies and antigen-binding fragments are useful for the treatment or prevention of cancer, osteoporosis, or other immune diseases. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/112098 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/24 (20130101) Original (OR) Class C07K 2317/565 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897953 | Regev et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Ana Carrizosa Anderson (Boston, Massachusetts); Ayshwarya Subramanian (Cambridge, Massachusetts); Orit Rozenblatt-Rosen (Cambridge, Massachusetts) |
| ABSTRACT | This invention relates generally to compositions and methods for modulating complement component 3 (C3) activity or expression to treat, control or otherwise influence tumors and tissues, including cells and cell types of the tumors and tissues, and malignant, microenvironmental, or immunologic states of the tumor cells and tissues. The invention also relates to methods of diagnosing, prognosing and/or staging of tumors, tissues and cells. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/622636 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/28 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897969 | Tsimikas et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sotirios Tsimikas (San Diego, California); Joseph L. Witztum (San Diego, California); Xuchu Que (San Diego, California) |
| ABSTRACT | The disclosure provides for methods and treatments of ischemic injury, reperfusion injury, stroke and myocardial infarctions by administering within minutes to hours an antibody or antibody fragment that bind to and inhibits the biological activity of OxPL in an affected tissue. |
| FILED | Friday, October 26, 2018 |
| APPL NO | 16/759331 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 39/39583 (20130101) A61K 45/06 (20130101) A61K 2039/54 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 9/10 (20180101) Peptides C07K 16/44 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897983 | Bolskar et al. |
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| FUNDED BY |
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| APPLICANT(S) | TDA Research, Inc (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Robert Donald Bolskar (Arvada, Colorado); James William Raebiger (Golden, Colorado); Rhia M Martin (Arvada, Colorado); Silvia De Vito Luebben (Golden, Colorado) |
| ABSTRACT | Crosslink-forming monomers, comprising reverse-acrylate groups, and crosslinked polymer networks formed by the polymerization of monomers that comprise said reverse-acrylate crosslink-forming monomers. Crosslink-forming monomers, comprising reverse-acrylate groups, comprising an alkyl, an aryl, an alkoxyl, and an alkylamino group bridging one or more reverse-acrylate groups. Crosslink-forming monomers, comprising reverse-acrylate groups, comprising an alkyl, an aryl, an alkoxyl, and an alkylamino ester groups. Crosslink-forming monomers, comprising reverse-acrylate groups, comprising alkyl groups where the group is selected from the group consisting of a methyl, an ethyl, a propyl, an n-butyl and a t-butyl. Reverse-acrylate crosslink-forming monomers comprise a chemical structure where the two or more polymerizable carbon-carbon double bonds are connected by a crosslinking group on the opposite side of the hydrolysable ester groups relative to normal crosslinking acrylate monomers. The crosslink-forming monomers herein form crosslinked polymer networks that do not lose their crosslinking upon hydrolysis of the ester linkages. |
| FILED | Tuesday, March 16, 2021 |
| APPL NO | 17/203648 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 222/1025 (20200201) Original (OR) Class C08F 2438/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898129 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Abraham P. Lee (Irvine, California); Xiaolin Wang (Shanghai, China PRC); Duc Phan (Fountain Valley, California); Christopher C. W. Hughes (Irvine, California); Steven C. George (St. Louis, Missouri) |
| ABSTRACT | A pressure regulator module for a chip-based microfluidic platform is provided. The module includes a microfluidic channel for passing flowable material from the inlet region through the outlet region and into a downstream compartment; one or more microvalves fluidly connected to the microfluidic channel and upstream of the outlet region; and one or more reservoirs fluidly connected to the microvalves, for receiving flowable material diverted by the microvalves, where a flow of flowable material passing from the inlet region toward the downstream compartment is at least partially diverted by the microvalves into the reservoirs as a result of a pressure increase in the microfluidic channel. In some versions, the microvalves are capillary burst valves. A microfluidic chip containing the module and a method of using the module are provided. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 17/492263 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2300/0864 (20130101) B01L 2400/0688 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 29/10 (20130101) C12M 41/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898142 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Omar Abudayyeh (Cambridge, Massachusetts) |
| ABSTRACT | The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect both DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/645571 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 2300/123 (20130101) B01L 2300/126 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2800/80 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898162 | Thomson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | James A. Thomson (Madison, Wisconsin); Junying Yu (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 16/818958 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0607 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2501/60 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2502/99 (20130101) C12N 2510/00 (20130101) C12N 2799/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898166 | Vizcardo et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Raul E. Vizcardo (Foster City, California); Nicholas P. Restifo (Chevy Chase, Maryland) |
| ABSTRACT | Disclosed are methods of preparing thymic organoids according to embodiments of the invention. Also disclosed are methods of preparing thymic emigrant cells in vitro, according to embodiments of the invention. Also disclosed are methods of treating or preventing a condition in a mammal, e g., cancer. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/648008 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/065 (20130101) Original (OR) Class C12N 2500/98 (20130101) C12N 2501/15 (20130101) C12N 2501/41 (20130101) C12N 2501/105 (20130101) C12N 2501/117 (20130101) C12N 2501/415 (20130101) C12N 2506/45 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898167 | Huebsch et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone (San Francisco, California) |
| ASSIGNEE(S) | The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Gladstone (San Francisco, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Nathaniel Huebsch (San Bruno, California); Bruce Conklin (San Francisco, California); Kevin E. Healy (Moraga, California); Peter Loskill (Stuttgart, Germany) |
| ABSTRACT | The invention relates to devices, methods, kits, and compositions for in vitro generation of three-dimensional micro-tissues that are accurate models of heart, skeletal muscle, neuronal, and other tissues. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/079720 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/12 (20130101) C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class C12N 2533/30 (20130101) C12N 2535/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898168 | Que et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Jianwen Que (Fort Lee, New Jersey); Yongchun Zhang (Fort Lee, New Jersey) |
| ABSTRACT | The current invention provides for methods of promoting differentiation of human pluripotent stem cells into esophageal progenitor cells as well as the cells obtained from the methods, solutions, compositions, and pharmaceutical compositions comprising such cells. The current invention also provides for methods of using the esophageal progenitor cells for treatment and prevention of disease, and kits. |
| FILED | Wednesday, October 10, 2018 |
| APPL NO | 16/156401 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/37 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0679 (20130101) Original (OR) Class C12N 2500/38 (20130101) C12N 2500/90 (20130101) C12N 2500/99 (20130101) C12N 2501/11 (20130101) C12N 2501/15 (20130101) C12N 2501/16 (20130101) C12N 2501/115 (20130101) C12N 2501/119 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2501/998 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/23 (20130101) C12N 2506/45 (20130101) C12N 2513/00 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898169 | Kim et al. |
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| FUNDED BY |
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| APPLICANT(S) | The McLean Hospital Corporation (Belmont, Massachusetts) |
| ASSIGNEE(S) | The McLean Hospital Corporation (Belmont, Massachusetts) |
| INVENTOR(S) | Kwang-Soo Kim (Lexington, Massachusetts); Young Cha (Lexington, Massachusetts) |
| ABSTRACT | Disclosed herein are methods of generating induced pluripotent stem cells. The method involves providing a quantity of somatic or non-embryonic cells, contacting the contacting the somatic or non-embryonic cells with a quantity of one or more programming factors and one or more RNA molecules, and culturing the somatic or non-embryonic cells for a period of time sufficient to generate at least one induced pluripotent stem cell. Various reprogramming factors and RNA molecules for use in the methods are disclosed herein. Also disclosed are cell lines and pharmaceutical compositions generated by use of the methods. |
| FILED | Friday, April 23, 2021 |
| APPL NO | 17/239059 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/141 (20130101) C12N 2310/141 (20130101) C12N 2330/10 (20130101) C12N 2501/65 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/606 (20130101) C12N 2506/1307 (20130101) C12N 2510/00 (20130101) C12N 2799/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898176 | Gersbach et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Charles Gersbach (Durham, North Carolina); David Ousterout (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are transcription activator-like effector nuclease (TALEN)-related compositions and methods of using said TALENs for correcting mutant genes. |
| FILED | Tuesday, June 02, 2020 |
| APPL NO | 16/890232 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Peptides C07K 14/4708 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898179 | Maianti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Juan Pablo Maianti (Revere, Massachusetts); David R. Liu (Lexington, Massachusetts) |
| ABSTRACT | Provided herein are systems, compositions, kits, and methods for the suppression of pain (e.g., chronic pain). Genes encoding ion channels (e.g., SCN9A) responsible for the propagation pain signals in neurons (e.g., DRG neurons) may be edited using a genome editing agent (e.g., a nucleobase editor). In some embodiments, loss-of-function ion channel mutants are generated, leading to pain suppression. In some embodiments, the genome editing agent is administered locally to the site of pain or to the nerves responsible for propagation of the pain signal. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 16/492548 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0029 (20130101) A61K 9/0053 (20130101) A61K 31/7088 (20130101) A61K 38/50 (20130101) A61K 38/465 (20130101) A61K 48/00 (20130101) Peptides C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/78 (20130101) Original (OR) Class C12N 9/96 (20130101) C12N 15/11 (20130101) C12N 2310/20 (20170501) C12N 2320/31 (20130101) C12N 2320/32 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 305/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898207 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Yong-Chen Lu (Rockville, Maryland); Peter Fitzgerald (Silver Spring, Maryland); Zhili Zheng (Gaithersburg, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed are methods of isolating paired T cell receptor (TCR) alpha and beta chain sequences, or an antigen-binding portion thereof. Also disclosed are methods of automatically identifying the TCR alpha and beta chain V segment sequences and CDR3 sequences of a TCR having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Methods of preparing a population of cells that express paired TCR alpha and beta chain sequences, or an antigen-binding portion thereof, are also disclosed. Isolated pairs of TCR alpha and beta chain sequences and isolated populations of cells prepared by the methods are also disclosed. |
| FILED | Wednesday, March 28, 2018 |
| APPL NO | 16/495508 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/7051 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 15/1003 (20130101) C12N 15/1096 (20130101) C12N 2502/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/10 (20190201) G16B 30/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899014 | Cornish et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Virginia Wood Cornish (New York, New York); Nili Ostrov (Brookline, Massachusetts); Miguel Jimenez (Winthrop, Massachusetts); Sonja Billerbeck (Groningen, Netherlands) |
| ABSTRACT | The present invention provides sensor cells comprising a receptor that binds to an analyte indicative of the presence of an agent, where binding of the analyte to the receptor triggers a detection event that is indicative of the presence of the agent. In certain embodiments, the detection event is appearance of a reporter detectable by the naked eye. The present invention also provides uses of such sensor cells for detecting the presence of an agent in a sample. |
| FILED | Friday, June 19, 2020 |
| APPL NO | 16/906669 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/005 (20130101) C12Q 1/06 (20130101) C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/566 (20130101) Original (OR) Class G01N 33/569 (20130101) G01N 33/5023 (20130101) G01N 33/5038 (20130101) G01N 33/5695 (20130101) G01N 33/56911 (20130101) G01N 33/56916 (20130101) G01N 33/56961 (20130101) G01N 2333/726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899020 | Griffiths et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Leigh G. Griffiths (Davis, California); Katherine Y. Gates (Davis, California); Ailsa J. Dalgliesh (Davis, California); Maelene L. Wong (Davis, California) |
| ABSTRACT | This invention provides methods for the screening and identification of antigenic components in a tissue or organ of interest. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 16/499057 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) Original (OR) Class G01N 33/6848 (20130101) G01N 33/6857 (20130101) G01N 33/54306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11896349 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Nathaniel Braman (Bethel Park, Pennsylvania) |
| ABSTRACT | Embodiments discussed herein facilitate determination of a response to treatment and/or a prognosis for a tumor based at least in part on features of tumor-associated vasculature (TAV). One example embodiment is a method, comprising: accessing a medical imaging scan of a tumor, wherein the tumor is segmented on the medical imaging scan; segmenting tumor-associated vasculature (TAV) associated with the tumor based on the medical imaging scan; extracting one or more features from the TAV; providing the one or more features extracted from the TAV to a trained machine learning model; and receiving, from the machine learning model, one of a predicted response to a treatment for the tumor or a prognosis for the tumor. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116319 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/004 (20130101) A61B 5/08 (20130101) A61B 5/0035 (20130101) A61B 5/02007 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/12 (20170101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20036 (20130101) G06T 2207/20081 (20130101) G06T 2207/30061 (20130101) G06T 2207/30068 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896943 | Mirkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Seungkyu Lee (Evanston, Illinois); Cindy Yizhe Zheng (Evanston, Illinois); Katherine E. Bujold (Magog, Canada) |
| ABSTRACT | Methods of stabilizing DNA-engineered crystals can include cross-linking the hybridized oligonucleotides. Stabilized crystals can have improved chemical and thermal stability. |
| FILED | Friday, May 22, 2020 |
| APPL NO | 16/882002 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/18 (20130101) B01J 13/0043 (20130101) Original (OR) Class Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896978 | Glezer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
| ASSIGNEE(S) | MESO SCALE TECHNOLOGIES, LLC. (Rockville, Maryland) |
| INVENTOR(S) | Eli N. Glezer (Del Mar, California); Stephen Higgins (Gaithersburg, Maryland); Sandor Kovacs (Middletown, Delaware); Sudeep Kumar (Hackettstown, New Jersey); Kenneth Page (Martinsburg, Virginia); Kristian Roth (Gaithersburg, Maryland); George Sigal (Rockville, Maryland) |
| ABSTRACT | Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/032524 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 7/525 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2200/16 (20130101) B01L 2200/027 (20130101) B01L 2200/146 (20130101) B01L 2200/0605 (20130101) B01L 2200/0621 (20130101) B01L 2200/0631 (20130101) B01L 2300/087 (20130101) B01L 2300/0645 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0883 (20130101) B01L 2400/0487 (20130101) B01L 2400/0688 (20130101) B01L 2400/0694 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897087 | Hardy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); Fraunhofer USA (Plymouth, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan); Fraunhofer USA (Plymouth, Michigan) |
| INVENTOR(S) | Aaron Hardy (East Lansing, Michigan); Timothy A. Grotjohn (Okemos, Michigan); Edward K. Drown (Haslett, Michigan); Michael Becker (East Lansing, Michigan) |
| ABSTRACT | A polishing apparatus is provided. Another aspect pertains to a self-leveling polishing apparatus for smoothing diamonds. Yet another aspect of the present system uses a ball and swivel joint in a diamond polishing machine. A further aspect employs a polishing apparatus including a diamond-holder, an elongated arm using gravity to apply downward polishing pressure of the diamond workpiece against a polishing wheel, and a sweeping transmission to cause the holder to radially move across the rotating polishing wheel. |
| FILED | Wednesday, March 09, 2022 |
| APPL NO | 17/922728 |
| ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Machines, Devices, or Processes for Grinding or Polishing; Dressing or Conditioning of Abrading Surfaces; Feeding of Grinding, Polishing, or Lapping Agents B24B 9/161 (20130101) Original (OR) Class B24B 37/26 (20130101) B24B 37/105 (20130101) B24B 41/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897101 | Harris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico) |
| INVENTOR(S) | John Richardson Harris (Albuquerque, New Mexico); Rufus Cooksey (Albuquerque, New Mexico) |
| ABSTRACT | A flexible implement positioner that is lockably installable around abutting flanges of abutting tubes enables an implement, such as a temperature gauge, to be desirably positioned near the joint between the abutting flanges and enable the implement to monitor the joint between the flanges. The implement positioner includes a plurality of body segments hingedly connected to one another in an end to end relationship, with one end including a lock body segment and the opposite end including a lock body segment having a lock lever hingedly mounted thereon, the lock lever positionable in engagement with the lock body segment and pivotal to lockably engage the lock lever when installing the implement positioner on one of the flanges. |
| FILED | Tuesday, July 14, 2020 |
| APPL NO | 16/929049 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 27/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897140 | Wandzel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Arthur Richard Wandzel (Orchard Lake, Michigan); Stefanie Tellex (Providence, Rhode Island) |
| ABSTRACT | A system and method of operating a mobile robot to perform tasks includes representing a task in an Object-Oriented Partially Observable Markov Decision Process model having at least one belief pertaining to a state and at least one observation space within an environment, wherein the state is represented in terms of classes and objects and each object has at least one attribute and a semantic label. The method further includes receiving a language command identifying a target object and a location corresponding to the target object, updating the belief associated with the target object based on the language command, driving the mobile robot to the observation space identified in the updated belief, searching the updated observation space for each instance of the target object, and providing notification upon completing the task. In an embodiment, the task is a multi-object search task. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 17/280365 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1661 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897592 | Sylvia |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Russell M Sylvia (South Dartmouth, Massachusetts) |
| ABSTRACT | A propeller pitch adjustment assembly is provided with a base hub operatively connected by blade shafts to propeller blades in which each blade rotates about an axis of each shaft. Each blade shaft is radially disposed about a propeller drive shaft and parallel to a pressure flange of a base hub spring plate. The spring plate counterforces the blade rotation with a lever screw that impacts the plate. An opposing spring transfers a load to the plate. The equilibrium position of the plate is determined by the spring force on the lever and a counteracting force exerted on the lever by a lift force generated by fluid flow over a propeller blade. A capping mechanism can provide a preload to the spring. A force exerted by the lift of the blade on the lever screw results in a blade pitch change. |
| FILED | Monday, August 21, 2023 |
| APPL NO | 18/235968 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Marine Propulsion or Steering B63H 3/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897933 | Tran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Eric Tran (Portland, Oregon); Yong-Chen Lu (Rockville, Maryland); Anna Pasetto (Stockholm, Sweden); Paul F. Robbins (Chevy Chase, Maryland); Steven A. Rosenberg (Potomac, Maryland); Zhili Zheng (Gaithersburg, Maryland) |
| ABSTRACT | Disclosed is an isolated or purified T cell receptor (TCR) having antigenic specificity for mutated Kirsten rat sarcoma viral oncogene homolog (KRAS) presented in the context of an HLA-Cw*0802 molecule. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions are also provided. Also disclosed are methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/345390 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/82 (20130101) C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 2015/8518 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57407 (20130101) G01N 2333/7051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898000 | Sotzing |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Gregory A. Sotzing (Storrs, Connecticut) |
| ABSTRACT | All organic, dielectric polymers with high discharge efficiency at elevated operation temperatures are reported. |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 16/919339 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/124 (20130101) Original (OR) Class C08G 2261/60 (20130101) C08G 2261/90 (20130101) C08G 2261/418 (20130101) C08G 2261/3342 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898082 | Harvey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin G. Harvey (Ridgecrest, California); Andrew P. Chafin (Ridgecrest, California); Michael D. Garrison (Ridgecrest, California) |
| ABSTRACT | This invention describes resins with phosphate cores and a simple, three-step process for their synthesis. Preferred resins are cyanate ester resins with bridging phosphate groups. These resins can be cured to produce thermoset polymers having Tgs of between 131 and >360° C. depending on the number of cyanate ester groups per phosphate and the substitution pattern of the aromatic rings. The high char yields of these resins, up to about 67%, coupled with the phosphate core means that these materials will have applications as fire-resistant polymers. Additionally, these materials can potentially be blended with conventional cyanate esters or other compatible thermosetting resins to improve the fire resistance of composite materials. Other applications may include use in fire-resistant circuit boards, or as surface coatings to reduce flammability of conventional composite materials or thermoplastics. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/065321 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/12 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/04 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 21/12 (20130101) C09K 21/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898141 | Nicol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert Nicol (Cambridge, Massachusetts); Lauren Andrews (Cambridge, Massachusetts); Tarjei Mikkelsen (Cambridge, Massachusetts); Christopher Voigt (Belmont, Massachusetts) |
| ABSTRACT | Disclosed is a method of generating a set of sequence-verified nucleic acid elements for the combinatorial construction of genetic elements. The method includes: providing a plurality of nucleic acid parts; assembling nucleic acid parts to form a one or more nucleic acid elements, wherein the nucleic acid elements include at least two sequences selected from the plurality of parts; and determining the sequence of the nucleic acid elements. Further disclosed is a pool of higher-order nucleic acid constructs or amplification products thereof, comprising one or more nucleic acid elements as well as kits including a pool of sequence-verified nucleic acid elements of claims and/or a pool of higher-order nucleic acid constructs; and a plurality of primers for retrieving one or more sequence-verified nucleic acid elements and/or higher-order nucleic acid constructs. |
| FILED | Wednesday, May 27, 2015 |
| APPL NO | 15/313863 |
| ART UNIT | 1699 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/66 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 15/1082 (20130101) C12N 15/1093 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/20 (20190201) G16B 30/00 (20190201) G16B 30/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898148 | Perkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SynPloid Biotek, LLC (Savannah, Georgia) |
| ASSIGNEE(S) | CarryGenes Bioengineering, LLC (Savannah, Georgia) |
| INVENTOR(S) | Edward Perkins (Savannah, Georgia); Amy Greene (Savannah, Georgia) |
| ABSTRACT | The present invention provides a novel method for targeted integration of nucleic acids onto an autonomously replicating nucleic acid using site-directed recombination that allows for sequential loading of multiple delivery vectors using a single selectable marker. |
| FILED | Wednesday, April 12, 2017 |
| APPL NO | 16/092828 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) Original (OR) Class C12N 15/65 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898166 | Vizcardo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Raul E. Vizcardo (Foster City, California); Nicholas P. Restifo (Chevy Chase, Maryland) |
| ABSTRACT | Disclosed are methods of preparing thymic organoids according to embodiments of the invention. Also disclosed are methods of preparing thymic emigrant cells in vitro, according to embodiments of the invention. Also disclosed are methods of treating or preventing a condition in a mammal, e g., cancer. |
| FILED | Wednesday, September 19, 2018 |
| APPL NO | 16/648008 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/065 (20130101) Original (OR) Class C12N 2500/98 (20130101) C12N 2501/15 (20130101) C12N 2501/41 (20130101) C12N 2501/105 (20130101) C12N 2501/117 (20130101) C12N 2501/415 (20130101) C12N 2506/45 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898187 | Jewett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Weston K. Kightlinger (Evanston, Illinois); Liang Lin (Evanston, Illinois); Milan Mrksich (Hinsdale, Illinois) |
| ABSTRACT | Disclosed are components, systems, and methods for glycoprotein or recombinant glycoprotein protein synthesis in vitro and in vivo. In particular, the present invention relates to components, systems, and methods for identifying amino acid glycosylation tag motifs for N-glycosyltransferases and the use of the identified amino acid glycosylation tag motifs in methods for preparing glycoproteins and recombinant glycoproteins in vitro and in vivo. |
| FILED | Wednesday, August 15, 2018 |
| APPL NO | 16/639500 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1051 (20130101) C12N 15/1044 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/005 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6851 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898203 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Vikram Pattanayak (Wellesley, Massachusetts); Karl Petri (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions for performing highly sensitive in vitro assays to define substrate preferences and off-target sites of nucleic-acid binding, modifying, and cleaving agents. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 16/386472 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1058 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class Enzymes C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898207 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Yong-Chen Lu (Rockville, Maryland); Peter Fitzgerald (Silver Spring, Maryland); Zhili Zheng (Gaithersburg, Maryland); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | Disclosed are methods of isolating paired T cell receptor (TCR) alpha and beta chain sequences, or an antigen-binding portion thereof. Also disclosed are methods of automatically identifying the TCR alpha and beta chain V segment sequences and CDR3 sequences of a TCR having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Methods of preparing a population of cells that express paired TCR alpha and beta chain sequences, or an antigen-binding portion thereof, are also disclosed. Isolated pairs of TCR alpha and beta chain sequences and isolated populations of cells prepared by the methods are also disclosed. |
| FILED | Wednesday, March 28, 2018 |
| APPL NO | 16/495508 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/7051 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 15/1003 (20130101) C12N 15/1096 (20130101) C12N 2502/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/10 (20190201) G16B 30/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898271 | Estevez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph Evans Estevez (Ridgecrest, California); Gretchen Hawes Hefley (Ridgecrest, California); Michael Bernard Celestine (Ridgecrest, California) |
| ABSTRACT | The method of the present invention for making a BNNT fabric comprises dispersing Boron-Nitride nanotubes at loading greater than 5 weight % in an electrospinning delivery solution; electrospinning the delivery solution onto a collector thereby forming a mat comprised of BNNT-PAN nano fibers; and, finally removing any electrospinning delivery solution from the mat leaving a fabric of intertwined Boron-Nitride nanotubes. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/723297 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/583 (20130101) C04B 35/62227 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Original (OR) Class Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/58 (20130101) D06M 11/74 (20130101) D06M 2101/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898315 | Lamie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Nathan J Lamie (Hanover, New Hampshire); Leonard Zabilansky (Hanover, New Hampshire); Christopher J Donnelly (Hanover, New Hampshire); Jordan M Hodge (Hanover, New Hampshire); William Burch (Hanover, New Hampshire) |
| ABSTRACT | In one embodiment, an ice management system is provided for removing an amount of oil from a surface of a body of water. The ice management system includes an ice frame having an ice fence coupled with an ice cage, an oil skimmer device disposed within the ice frame, and an ice deflection assembly coupled with the ice frame. The ice deflection assembly includes an auger coupled with a motor. The auger includes a drum and a deflection mechanism, and the motor is configured to rotate the auger. The deflection mechanism includes a spiral flight or a series of tabs arranged in a corkscrew pattern about the drum. The ice fence includes a plurality of curved vanes. The curved vanes have a bent rectangular plate shape. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/359399 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/40 (20130101) C02F 2101/32 (20130101) C02F 2103/007 (20130101) C02F 2201/002 (20130101) Hydraulic Engineering E02B 15/02 (20130101) E02B 15/06 (20130101) E02B 15/10 (20130101) E02B 15/048 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898829 | Graham |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Simmonds Precision Products, Inc. (Vergennes, Vermont) |
| ASSIGNEE(S) | Simmonds Precision Products, Inc. (Vergennes, Vermont) |
| INVENTOR(S) | Jason Graham (Prior Lake, Minnesota) |
| ABSTRACT | A system includes a guided munition having a housing. A first reservoir is defined within the housing holding a first chemical reactant. A second reservoir is defined within the housing, wherein the second reservoir holds a second chemical reactant configured to undergo an endothermic reaction with the first chemical reactant. A frangible barrier separates between the first and second reservoirs. The frangible barrier is configured to break under forces acting on the guided munition as the guided munition is fired from a weapon. An electronic device can be housed within the housing in thermal contact with at least one of the first reservoir and/or second reservoir for cooling the electronic device with an endothermic reaction upon mixing of the first and second chemical reactants. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/104222 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 5/00 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 15/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898919 | Sotoudeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Fiber Optic Systems Corporation (San Jose, California) |
| ASSIGNEE(S) | Intelligent Fiber Optic Systems Corporation (Fremont, California) |
| INVENTOR(S) | Vahid Sotoudeh (Los Altos, California); Behzad Moslehi (Los Altos, California); Joshua Kuehn (Boulder Creek, California); Richard J. Black (Menlo Park, California) |
| ABSTRACT | A temperature correcting pressure gauge which has a diaphragm having at least one surface coupled to a source of pressure to be measured, the diaphragm first surface having a first FBG from a first optical fiber attached in an appropriately sensitive region of the diaphragm, a FBG from a second optical fiber attached to the opposite surface from the first FBG, the first and second FBGs reflecting or transmitting optical energy of decreasing or increasing wavelength, respectively, in response to an applied pressure. The first and second FBGs have nominal operating wavelength ranges that are adjacent to each other but are exclusive ranges and the FBGs also have closely matched pressure coefficients and temperature coefficients. |
| FILED | Thursday, November 04, 2021 |
| APPL NO | 17/518598 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/3206 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/246 (20130101) Original (OR) Class G01L 1/2281 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899014 | Cornish et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Virginia Wood Cornish (New York, New York); Nili Ostrov (Brookline, Massachusetts); Miguel Jimenez (Winthrop, Massachusetts); Sonja Billerbeck (Groningen, Netherlands) |
| ABSTRACT | The present invention provides sensor cells comprising a receptor that binds to an analyte indicative of the presence of an agent, where binding of the analyte to the receptor triggers a detection event that is indicative of the presence of the agent. In certain embodiments, the detection event is appearance of a reporter detectable by the naked eye. The present invention also provides uses of such sensor cells for detecting the presence of an agent in a sample. |
| FILED | Friday, June 19, 2020 |
| APPL NO | 16/906669 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/005 (20130101) C12Q 1/06 (20130101) C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/566 (20130101) Original (OR) Class G01N 33/569 (20130101) G01N 33/5023 (20130101) G01N 33/5038 (20130101) G01N 33/5695 (20130101) G01N 33/56911 (20130101) G01N 33/56916 (20130101) G01N 33/56961 (20130101) G01N 2333/726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899122 | Smith |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Assured Information Security, Inc. (Rome, New York) |
| ASSIGNEE(S) | ASSURED INFORMATION SECURITY, INC. (Rome, New York) |
| INVENTOR(S) | Jason Eric Smith (Oneida, New York) |
| ABSTRACT | Geolocating one or more emitters includes obtaining a set of lines of bearing (LOBs) indicative of location(s) of emitter(s), determining intersections of LOBs of the set and generating clusters informed by those intersections, assigning the LOBs of the set to cluster(s) based on proximity, identifying a cluster having the greatest number of assigned LOBs from the set; determining an emitter location area based on a best point estimate for the cluster, and indicating a location of an emitter as the emitter location area. Additional emitters can be located by removing from the set of LOBs those LOBs assigned to the identified cluster, and repeating aforementioned aspects. Initially, the set of LOBs can be selected from a larger collection as a representative subset thereof. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/281835 |
| ART UNIT | 2682 — Optics |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/0205 (20130101) G01S 5/0249 (20200501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899232 | Geng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AdValue Photonics, Inc. (Tucson, Arizona) |
| ASSIGNEE(S) | AdValue Photonics, Inc. (Tucson, Arizona) |
| INVENTOR(S) | Jihong Geng (Tucson, Arizona); Shibin Jiang (Tucson, Arizona) |
| ABSTRACT | Method for fabricating of all-optical-fiber based optical polarizer devoid of fusing of first and second optical fibers. The method includes a process of forming a substantially adiabatic optical fiber taper by pulling an optical fiber and interrupting this process when an optical power parameter measured at an output of the optical fiber is reduced below a pre-defined threshold as a result of said pulling. An optically-tapered single-mode polarization-maintaining optical fiber element fabricated according to the method and configured as such all-optical-fiber polarizer. |
| FILED | Monday, June 06, 2022 |
| APPL NO | 17/833347 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/3025 (20130101) Original (OR) Class G02B 6/4209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899491 | Sherman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (, None) |
| INVENTOR(S) | Matthew J. Sherman (Succasunna, New Jersey); Mritunjay Sinha (Parsippany, New Jersey); Lawrence Yang (Lake Hiawatha, New Jersey) |
| ABSTRACT | The system and method generates a pulse or a signal that is transmitted between a central processing unit or processor and an Ethernet integrated circuit card to program a trigger generator in the IC. The pulse is effectively a 1PPS signal that is provided to the IC, which may be in the form a field programmable gate array to enable timing synchronization. The trigger in the IC may also generates an interrupt to the processor so a driver in the CPU is instructed to set the next trigger. For the trigger to be accurately controlled, the control routine is implemented in the driver existing in kernel space rather than user space. A routine or protocol periodically polls the interrupt to determine when the trigger must be reset. |
| FILED | Tuesday, September 27, 2022 |
| APPL NO | 17/953992 |
| ART UNIT | 2186 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/12 (20130101) Original (OR) Class G06F 15/7814 (20130101) Multiplex Communication H04J 3/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899740 | Ezick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | QUALCOMM Incorporated (San Diego, California) |
| ASSIGNEE(S) | QUALCOMM Incorporated (San Diego, California) |
| INVENTOR(S) | James Ezick (Canonsburg, Pennsylvania); Thomas Henretty (Brooklyn, New York); Chanseok Oh (Fort Lee, New Jersey); Jonathan Springer (Carbondale, Illinois) |
| ABSTRACT | We present the architecture of a high-performance constraint solver R-Solve that extends the gains made in SAT performance over the past fifteen years on static decision problems to problems that require on-the-fly adaptation, solution space exploration and optimization. R-Solve facilitates collaborative parallel solving and provides an efficient system for unrestricted incremental solving via Smart Repair. R-Solve can address problems in dynamic planning and constrained optimization involving complex logical and arithmetic constraints. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/113814 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 9/54 (20130101) G06F 17/11 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) G06N 7/00 (20130101) G06N 7/01 (20230101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11900018 | Maxwell, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | XEROX CORPORATION (Norwalk, Connecticut) |
| INVENTOR(S) | John T. Maxwell, III (Santa Clara, California); Matthew Klenk (San Francisco, California); Johan de Kleer (Los Altos, California) |
| ABSTRACT | The techniques disclosed herein help designers find interesting designs for small electrical, mechanical, and/or hydraulic mechanisms by exhaustively enumerating the design space given a library of components and a maximum number of components allowed per design. Some embodiments work by creating a design space grammar of designs, solving the equations associated with parts of the grammar, and putting the solutions into equivalence classes. This dramatically reduces the number of designs that have to be evaluated to see if they satisfy the design criteria. The result is often a small number of base designs that show the range of possible solutions to the design problem. |
| FILED | Wednesday, July 31, 2019 |
| APPL NO | 16/527668 |
| ART UNIT | 2146 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 17/11 (20130101) G06F 30/00 (20200101) Original (OR) Class G06F 2111/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11900191 | Church |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts) |
| ABSTRACT | The present invention relates to methods of storing data using one or more nucleic acids. |
| FILED | Tuesday, April 20, 2021 |
| APPL NO | 17/235196 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/00 (20130101) G06K 19/022 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/123 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) G16B 30/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11900245 | Skorheim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Steven Skorheim (La Jolla, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Steven Skorheim (La Jolla, California); Maksim Bazhenov (La Jolla, California); Pavel Sanda (La Jolla, California) |
| ABSTRACT | Systems, devices, and methods are disclosed for decision making based on plasticity rules of a neural network. A method may include obtaining a multilayered model. The multilayered model may include an input layer including one or more input units. The multilayered model may include one or more hidden layers including one or more hidden units. Each input unit may have a first connection with at least one hidden unit. The multilayered model may include an output layer including one or more output units. The method may also include receiving an input at a first input unit. The method may include sending a first signal from the first input unit to at least one hidden unit via a first connection comprising a first strength. The method may also include making a decision based on the model receiving the input. |
| FILED | Thursday, August 30, 2018 |
| APPL NO | 16/643508 |
| ART UNIT | RD00 — Optics |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/049 (20130101) G06N 3/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11900562 | Braunreiter |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Tewksbury, Massachusetts) |
| INVENTOR(S) | Dennis C. Braunreiter (San Diego, California) |
| ABSTRACT | A system includes at least one imaging sensor configured to capture images of a target. The system also includes at least one controller configured to generate super-resolution images of the target using the captured images and identify multiple edges of the target using the super-resolution images. The at least one controller is also configured to identify an aimpoint on the target based on the identified edges of the target. In addition, the at least one controller is configured to update the aimpoint on the target as the target moves over time. The system may further include a high-energy laser (HEL) configured to generate an HEL beam that is directed towards the target, and the at least one controller may be configured to adjust one or more optical devices to direct the HEL beam at the identified aimpoint on the target. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 16/702279 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/4053 (20130101) Original (OR) Class G06T 3/4069 (20130101) G06T 3/4076 (20130101) G06T 5/50 (20130101) G06T 2207/10016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901122 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida); SPEL TECHNOLOGIES PRIVATE LIMITED (Pune, India) |
| ASSIGNEE(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida); SPEL TECHNOLOGIES PRIVATE LIMITED (Pune, India) |
| INVENTOR(S) | Wanjun Ben Cao (Tallahassee, Florida); Jin Yan (Tallahassee, Florida); Xujie Chen (Tallahassee, Florida); Jian-Ping Zheng (Tallahassee, Florida); Annadanesh Shellikeri (Tallahassee, Florida); Mark Andrew Hagen (Tallahassee, Florida) |
| ABSTRACT | A hybrid lithium-ion battery-capacitor (H-LIBC) energy storage device includes a hybrid composite cathode electrode having a lithium ion battery (LIB) cathode active material and a lithium ion capacitor (LIC) cathode active material. An anode electrode having a surface is pre-loaded and pressed with a lithium (Li) thin film source. The anode electrode is pre-lithiated with the lithium film source by positioning the Li film source on the surface of anode electrode after electrolyte filling and soaking processes, a separator and an organic solvent electrolytic solution including a lithium salt electrolyte are also provided. A method of making a hybrid lithium-ion battery-capacitor and a method of making a hybrid composite cathode for a hybrid lithium-ion battery-capacitor are also disclosed. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 17/552908 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/06 (20130101) Original (OR) Class H01G 11/24 (20130101) H01G 11/38 (20130101) H01G 11/46 (20130101) H01G 11/50 (20130101) H01G 11/52 (20130101) H01G 11/60 (20130101) H01G 11/62 (20130101) H01G 11/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901473 | Burger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Tobias Burger (Ann Arbor, Michigan); Byungjun Lee (Ann Arbor, Michigan); Dejiu Fan (Ann Arbor, Michigan); Andrej Lenert (Ann Arbor, Michigan); Stephen R. Forrest (Ann Arbor, Michigan) |
| ABSTRACT | To reach high efficiencies, thermophotovoltaic cells must utilize the broad spectrum of a radiative thermal source. One promising approach to overcome this challenge is to have low-energy photons reflected and reabsorbed by the thermal emitter, where their energy can have another chance at contributing toward photogeneration in the cell. However, current methods for photon recuperation are limited by insufficient bandwidth or parasitic absorption, resulting in large efficiency losses relative to theoretical limits. This work demonstrates nearly perfect reflection of low-energy photons (˜99%) by embedding an air layer within the TPV cell. This result represents a four-fold reduction in parasitic absorption relative to existing TPV cells. As out-of-band reflectance approaches unity, TPV efficiency becomes nearly insensitive to cell bandgap and emitter temperature. Accessing this regime unlocks a range of possible materials and heat sources that were previously inaccessible to TPV energy conversion. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232243 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/04 (20130101) C30B 25/22 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/043 (20141201) H01L 31/0264 (20130101) H01L 31/0687 (20130101) Original (OR) Class H01L 31/0735 (20130101) H01L 31/1852 (20130101) H01L 31/1896 (20130101) H01L 31/02327 (20130101) H01L 33/0093 (20200501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901476 | Pan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MICROLINK DEVICES, INC. (Niles, Illinois) |
| ASSIGNEE(S) | MICROLINK DEVICES, INC. (Niles, Illinois) |
| INVENTOR(S) | Noren Pan (Wilmette, Illinois); Glen Hillier (Spring Grove, Illinois); Duy Phach Vu (San Jose, California); Rao Tatavarti (Mount Prospect, Illinois); Christopher Youtsey (Libertyville, Illinois); David McCallum (West Chicago, Illinois); Genevieve Martin (Chicago, Illinois) |
| ABSTRACT | The present invention utilizes epitaxial lift-off in which a sacrificial layer is included in the epitaxial growth between the substrate and a thin film III-V compound solar cell. To provide support for the thin film III-V compound solar cell in absence of the substrate, a backing layer is applied to a surface of the thin film III-V compound solar cell before it is separated from the substrate. To separate the thin film III-V compound solar cell from the substrate, the sacrificial layer is removed as part of the epitaxial lift-off. Once the substrate is separated from the thin film III-V compound solar cell, the substrate may then be reused in the formation of another thin film III-V compound solar cell. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170133 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1844 (20130101) H01L 31/1852 (20130101) Original (OR) Class H01L 31/1896 (20130101) H01L 31/06875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901623 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Xuanke He (Atlanta, Georgia); Emmanouil Tentzeris (Atlanta, Georgia); Ryan Alexander Bahr (Peachtree City, Georgia); Yunnan Fang (Atlanta, Georgia) |
| ABSTRACT | An antenna system includes an antenna waveguide having a waveguide surface. A set of printed electronics includes conductors deposited onto the waveguide surface of the antenna waveguide. The system further includes at least one transceiver integrated circuit (IC), the transceiver integrated circuit having a surface assembly, wherein the surface assembly is adhesively coupled to the antenna waveguide and directly connected to the waveguide surface of the antenna waveguide. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 17/405661 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/364 (20130101) H01Q 1/2283 (20130101) H01Q 13/18 (20130101) H01Q 13/0233 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11902016 | Bedrosian |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | P. Stephan Bedrosian (McLean, Virginia) |
| ABSTRACT | A range is determined between two unsynchronized communications terminals in which a first terminal transmits a range request to a second terminal. The first terminal stores a first timestamp in memory corresponding to a time at which the range request message was transmitted. A range response is later received by the first terminal from the second terminal. The range response includes a residence time that characterizes an amount of time the second terminal required to send the range response after receiving the range request. The first terminal later stores a second timestamp in memory corresponding to a time at which the range response was received. Based on the second timestamp minus the first timestamp and the residence time, a roundtrip time for the range request is calculated. This roundtrip time can be used to calculate a distance between the first terminal and the second terminal based on the roundtrip time. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538146 |
| ART UNIT | 2471 — Multiplex and VoIP |
| CURRENT CPC | Multiplex Communication H04J 3/0661 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0864 (20130101) Wireless Communication Networks H04W 56/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11902407 | Medard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Muriel Medard (Belmont, Massachusetts); Derya Malak (Boston, Massachusetts); Alejandro Cohen (Brookline, Massachusetts) |
| ABSTRACT | Techniques are disclosed for an adaptive and causal random linear network coding (AC-RLNC) with forward error correction (FEC) for a communication channel with delayed feedback. An example methodology implementing the techniques includes transmitting one or more coded packets in a communication channel, determining a channel behavior of the channel, and adaptively adjusting a transmission of a subsequent coded packet in the first channel based on the determined channel behavior. The communication channel may be a point-to-point communication channel between a sender and a receiver. The channel behavior may be determined based on feedback acknowledgements provided by the receiver. The subsequent coded packet may be a random linear combination of one or more information packets. |
| FILED | Monday, December 12, 2022 |
| APPL NO | 18/064540 |
| ART UNIT | 2478 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0001 (20130101) H04L 1/004 (20130101) H04L 1/12 (20130101) H04L 1/0041 (20130101) H04L 1/0045 (20130101) H04L 1/0076 (20130101) H04L 1/1867 (20130101) H04L 45/24 (20130101) H04L 45/70 (20130101) H04L 47/38 (20130101) H04L 69/324 (20130101) Original (OR) Class Wireless Communication Networks H04W 28/0231 (20130101) H04W 28/0257 (20130101) H04W 40/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11902433 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (, None) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Wu (Eden Prairie, Minnesota); Ranga S. Ramanujan (Medina, Minnesota) |
| ABSTRACT | Embodiments for a networking device are disclosed. The networking device includes a private identity-based cryptographic (IBC) key issued for a first device. The networking device can receive an internet protocol (IP) packet from the first device. The networking device modifies the IP packet to form a modified IP packet, wherein modify the IP packet includes add an extension header to the IP packet. The extension header includes a source identifier identifying the first device, an indication of the key generation authority and an indication of an identity-based encryption (IBE) algorithm. The networking device also generates an identity-based signature (IBS) using the IBC algorithm with the source identifier as an identity input, the modified IP packet as a message input, and the private IBC key for the first device as a private key input. The modified IP packet and the IBS is then sent towards a destination of the IP packet. |
| FILED | Wednesday, August 29, 2018 |
| APPL NO | 16/115709 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0819 (20130101) H04L 9/0866 (20130101) Original (OR) Class H04L 63/0236 (20130101) H04L 63/0245 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11903330 | Shabani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Javad Shabani (Briarcliff Manor, New York); Matthieu C. Dartiailh (New York, New York) |
| ABSTRACT | The method of performing braiding operations can include providing a first Josephson junction including first gates. The method can include providing a second Josephson junction including second gates. The method can include tuning the first gates to dispose a first pair of Majorana fermions a first region. The method can include tuning the second gates to dispose a second pair of Majorana fermions in a second region. The method can include tuning the first gates to dispose a first Majorana fermion in the first region and to dispose a second Majorana fermion in a third region. The method can include tuning the second gates to dispose a third Majorana fermion in a fourth region and to dispose a fourth Majorana fermion in the second region. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 17/378375 |
| ART UNIT | 2896 — Cryptography and Security |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Electric solid-state devices not otherwise provided for H10N 60/01 (20230201) H10N 60/12 (20230201) Original (OR) Class H10N 60/128 (20230201) H10N 60/0912 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11896653 | Serda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Rita E. Serda (Albuquerque, New Mexico); C. Jeffrey Brinker (Albuquerque, New Mexico); Jacob Ongudi Agola (Albuquerque, New Mexico); Jimin Guo (Albuquerque, New Mexico); Sarah Adams (Albuquerque, New Mexico) |
| ABSTRACT | A silicified cell replica includes a silicified cell or a silicified subcellular fragment. The silicified cell replica may be used to induce an immunological response, treat a bacterial infection, or treat a patient with cancer. |
| FILED | Thursday, September 13, 2018 |
| APPL NO | 16/647245 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/6006 (20130101) A61K 2039/55594 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896935 | Darling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Seth B. Darling (Chicago, Illinois); Jeffrey W. Elam (Elmhurst, Illinois); Ruben Waldman (Chicago, Illinois) |
| ABSTRACT | Polymeric membranes are modified via SIS to promote membrane resilience, prolong membrane lifetime, and mitigate fouling. Modified membranes include an inorganic material within an outer portion of the modified membrane and a polymeric core that remains unmodified by the inorganic material. The polymer may be removed leaving an inorganic material patterned from an initial unmodified polymeric membrane. |
| FILED | Thursday, August 17, 2017 |
| APPL NO | 15/680064 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 67/0002 (20130101) B01D 67/0072 (20130101) B01D 67/0079 (20130101) B01D 69/02 (20130101) Original (OR) Class B01D 69/105 (20130101) B01D 69/125 (20130101) B01D 69/141 (20130101) B01D 69/148 (20130101) B01D 71/34 (20130101) B01D 71/36 (20130101) B01D 71/42 (20130101) B01D 71/68 (20130101) B01D 71/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896947 | Motkuri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Radha Kishan Motkuri (Richland, Washington); Jagannadha R. Bontha (Richland, Washington); B. Peter McGrail (Pasco, Washington) |
| ABSTRACT | A MOF production system and method of making are detailed for continuous and controlled synthesis of MOFs and MOF composites. The system can provide optimized yields of MOFs and MOF composites greater than or equal to 95%. |
| FILED | Tuesday, June 30, 2020 |
| APPL NO | 16/916110 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/06 (20130101) B01J 19/10 (20130101) Original (OR) Class B01J 19/0013 (20130101) B01J 20/226 (20130101) B01J 20/3085 (20130101) B01J 20/3204 (20130101) B01J 20/3236 (20130101) B01J 20/3293 (20130101) B01J 31/1691 (20130101) B01J 35/026 (20130101) B01J 37/0072 (20130101) B01J 2219/00051 (20130101) B01J 2219/0877 (20130101) B01J 2231/005 (20130101) B01J 2531/16 (20130101) B01J 2531/845 (20130101) B01J 2531/847 (20130101) Acyclic or Carbocyclic Compounds C07C 51/43 (20130101) C07C 51/43 (20130101) C07C 51/43 (20130101) C07C 51/418 (20130101) C07C 51/418 (20130101) C07C 51/418 (20130101) C07C 63/307 (20130101) C07C 63/307 (20130101) C07C 63/307 (20130101) C07C 65/05 (20130101) C07C 65/05 (20130101) C07C 65/05 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 3/003 (20130101) C07F 7/003 (20130101) C07F 15/045 (20130101) C07F 15/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898114 | Ruddy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Daniel Ruddy (Arvada, Colorado); Thomas Dwight Foust (Evergreen, Colorado); Trenton John Wilke (Seattle, Washington); Anh The To (Denver, Colorado); Andrew Wolf Bartling (Golden, Colorado); Martha Arellano-Trevino (Golden, Colorado) |
| ABSTRACT | The present disclosure relates to a composition that includes a compound having the structure R1O—(CH2O)n—R2 and a cetane number between about 65 and about 100, where n is between 1 and 10, inclusively, R1 includes a first alkyl group, and R2 includes a second alkyl group. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/546170 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 41/14 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/1852 (20130101) Original (OR) Class C10L 10/06 (20130101) C10L 10/12 (20130101) C10L 2200/0446 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898211 | Park |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Dan Mcfarland Park (Dublin, California) |
| ABSTRACT | UO2F2 biosensors, and related U-sensing and/or F-sensing genetic molecular components, genetic circuits, compositions, methods and systems are described, which in several embodiments can be used to detect and/or neutralize uranium and in particular bioavailable UO2F2. |
| FILED | Tuesday, February 04, 2020 |
| APPL NO | 16/781950 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/12 (20130101) C12N 15/52 (20130101) C12N 15/74 (20130101) C12N 15/635 (20130101) C12N 2830/002 (20130101) C12N 2830/55 (20130101) C12N 2840/002 (20130101) C12N 2840/105 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class Enzymes C12Y 207/13003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2520/00 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 9/18 (20130101) G21F 9/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898226 | Cramer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Corson L. Cramer (Knoxville, Tennessee); James O. Kiggans, Jr. (Oak Ridge, Tennessee); Amelia M. Elliott (Knoxville, Tennessee); David C. Anderson (Knoxville, Tennessee) |
| ABSTRACT | A method for additive manufacturing of a composite object containing a bonded network of boron carbide particles and aluminum occupying spaces between boron carbide particles, the method comprising: (i) producing a porous preform constructed of boron carbide by an additive manufacturing process in which particles of boron carbide are bonded together; and (ii) infiltrating molten aluminum, at a temperature of 1000-1400° C., into pores of said porous preform to produce said composite object constructed of boron carbide particles within an aluminum matrix, wherein the boron carbide is present in the composite object in an amount of 30-70 wt. %. The resulting composite material is also herein described. |
| FILED | Tuesday, February 25, 2020 |
| APPL NO | 16/800012 |
| ART UNIT | 1738 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1021 (20130101) B22F 2201/11 (20130101) B22F 2201/20 (20130101) B22F 2301/052 (20130101) B22F 2302/10 (20130101) B22F 2303/05 (20130101) B22F 2304/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 41/009 (20130101) C04B 41/88 (20130101) C04B 41/5155 (20130101) Alloys C22C 1/1036 (20130101) C22C 29/062 (20130101) Original (OR) Class C22C 29/067 (20130101) C22C 32/0057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898701 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RTX COPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Wenping Zhao (Glastonbury, Connecticut); Ellen Y. Sun (South Windsor, Connecticut); John P. Wesson (West Hartford, Connecticut); Paul F. Croteau (Columbia, Connecticut); Andrzej Ernest Kuczek (Bristol, Connecticut) |
| ABSTRACT | A composite pressure vessel assembly includes a plurality of lobes, each of the lobes having at least one interior wall and at least one curved wall, the plurality of lobes being positioned in a side by side arrangement and extending in a longitudinal direction from a first end to a second end. Also included is a plurality of end caps disposed at the ends of the lobes, wherein the plurality of lobes and end caps are formed of at least one fiber-reinforced polymer. A method of manufacturing a composite pressure vessel assembly is provided. The method includes forming a plurality of lobes consisting of at least one fiber-reinforced polymer. The method also includes forming a main body with the plurality of lobes, the lobes disposed in a side by side arrangement. |
| FILED | Thursday, December 08, 2022 |
| APPL NO | 18/077797 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 63/04 (20130101) B29C 70/305 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7156 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 1/16 (20130101) Original (OR) Class F17C 2201/056 (20130101) F17C 2201/0152 (20130101) F17C 2203/0604 (20130101) F17C 2203/0614 (20130101) F17C 2203/0617 (20130101) F17C 2203/0619 (20130101) F17C 2203/0636 (20130101) F17C 2203/0663 (20130101) F17C 2209/225 (20130101) F17C 2209/227 (20130101) F17C 2209/232 (20130101) F17C 2209/2109 (20130101) F17C 2209/2154 (20130101) F17C 2221/012 (20130101) F17C 2221/031 (20130101) F17C 2221/033 (20130101) F17C 2221/035 (20130101) F17C 2223/035 (20130101) F17C 2223/0123 (20130101) F17C 2260/018 (20130101) F17C 2270/0168 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898921 | Steuber |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Jason Steuber (Kansas City, Missouri) |
| ABSTRACT | An air bearing for calibrating a force measurement device comprises an inner wall, an outer wall, an upper wall, a lower wall, an internal chamber, an object retention opening, and a plurality of air outlets. The inner wall and outer wall each have a cylindrical shape with the outer wall being concentric with the inner wall. The upper wall and lower wall each have an annular shape and are attached to the inner wall and the outer wall. The internal chamber is formed by inner surfaces of the four walls, and is configured to retain compressed air. The object retention opening is formed by an outer surface of the inner wall and is configured to receive and retain an object. The air outlets are positioned along the inner wall and are configured to allow compressed air to flow from the internal chamber to the object retention opening. |
| FILED | Tuesday, May 17, 2022 |
| APPL NO | 17/746438 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 32/0607 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 25/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898960 | Riddle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Catherine Riddle (Idaho Falls, Idaho); Rick L. Demmer (Idaho Falls, Idaho) |
| ABSTRACT | A method for rapid detection of actinides including the steps of having a support including a colorimetric complexation, placing the support in communication with a sample through urinalysis, and receiving a visual indicator from the colorimetric complexation. The sample having an unknown concentration of at least one actinide within it. The colorimetric complexation is configured to activate when contacted by a threshold concentration of an actinide. |
| FILED | Thursday, September 02, 2021 |
| APPL NO | 17/465200 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class G01N 21/8803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899080 | Ohodnicki et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Paul Ohodnicki (Pittsburgh, Pennsylvania); Derek Lau (San Jose, California); Jagannath Devkota (Pittsburgh, Pennsylvania); Michael McHenry (Pittsburgh, Pennsylvania); Alex Leary (Pittsburgh, Pennsylvania); Richard Beddingfield (Raleigh, North Carolina); Michael Buric (Morgantown, West Virginia) |
| ABSTRACT | The invention provides a method for measuring the magnetic field of an electromagnetic component having the steps of: instrumenting one or more portions of an electromagnetic component by placing an optical fiber in electromagnetic communication with the one or more portions of said electromagnetic component; energizing the electromagnetic component; interrogating the optical fiber using light and an optical detector; and determining changes in the magnetic field incident on the optical fiber based on the detected changes in the light received by the optical detector. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 17/379389 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/032 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899953 | Brewer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas) |
| ABSTRACT | Disclosed in some examples are methods, systems, memory devices, and machine-readable mediums that allow a memory device to efficiently mark memory extents involved in an enhanced memory operation. An extent is marked if a meta state associated with the extent indicates that the extent is included in the enhanced memory operation. The largest memory extents of the operation are maintained in the memory device as a list of unmarked extents. When a primitive memory operation is received, the memory address is compared to the unmarked extents in the list to the meta state for that memory line. If the address is covered by the list of extents, or that line's meta state is marked, then the memory operation is performed including the enhanced memory operation. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823470 |
| ART UNIT | 2132 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0619 (20130101) G06F 3/0631 (20130101) G06F 3/0634 (20130101) Original (OR) Class G06F 3/0644 (20130101) G06F 3/0673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11900086 | Haile et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Jedediah T. Haile (Idaho Falls, Idaho); Bryan R. Beckman (Idaho Falls, Idaho); Sage R. Havens (Idaho Falls, Idaho); Jared A. Verba (Idaho Falls, Idaho); Garrett W. Larsen (Idaho Falls, Idaho); May R. Chaffin (Idaho Falls, Idaho); Rita A. Foster (Idaho Falls, Idaho) |
| ABSTRACT | Binaries configured for execution within respective computing environments may be disassembled into architecture-specific intermediate (AIL) representations. The AIL representations may be converted into canonical intermediate language (CIL) representations. The CIL representations may comprise normalized, architecture-independent code configured to characterize functionality of respective components of a binary (e.g., respective functions or the like). Feature vectors may be extracted from the CIL representations. The feature vectors may be used to identify components of respective binaries, assign security classifications to the binaries, and/or the like. |
| FILED | Tuesday, October 19, 2021 |
| APPL NO | 17/505613 |
| ART UNIT | 2191 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/43 (20130101) G06F 8/44 (20130101) Original (OR) Class G06F 8/52 (20130101) G06F 8/427 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901090 | Shivprasad et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Aditya Shivprasad (Los Alamos, New Mexico); Stuart Andrew Maloy (Albuquerque, New Mexico); Erik Luther (Los Alamos, New Mexico); Tarik Saleh (Los Alamos, New Mexico) |
| ABSTRACT | Hydrogen infused nuclear reactor core monoliths and processes for their production are disclosed. Such monoliths may function as both a core monolith and a moderator, providing structure and at least some moderation. Hydrogen infused monoliths may be complementary to or be used in lieu of separate moderators for thermalizing neutrons. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 17/492025 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 5/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901097 | Majkic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas); AMPEERS LLC (Houston, Texas) |
| INVENTOR(S) | Goran Majkic (Houston, Texas); Anis Ben Yahia (Houston, Texas); Wenbo Luo (Houston, Texas); Venkat Selvamanickam (Houston, Texas); Soumen Kar (Houston, Texas) |
| ABSTRACT | A round superconductor wire and method for fabricating same are disclosed. Embodiments are directed to a round superconductor wire including at least two superconductor tapes wound on a wire former. Each superconductor tape includes: bottom stabilizer and silver layers; substrate disposed above the bottom silver layer; buffer film stack disposed above the substrate; superconductor film disposed above the buffer film stack; top silver layer disposed above the superconductor film; and top stabilizer layer disposed above the top silver layer. At least one of the bottom stabilizer layer, bottom silver layer, substrate, buffer film stack, superconductor film, top silver layer, or top stabilizer layer is of a different width, thickness, or material composition in one of the superconductor tapes than in another of the superconductor tapes. These and other embodiments achieve a round superconductor wire having improved current density in high magnetic field applications when made in small diameters. |
| FILED | Monday, October 28, 2019 |
| APPL NO | 17/288838 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901123 | Signorelli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FastCAP Systems Corporation (Wakefield, Massachusetts) |
| ASSIGNEE(S) | FASTCAP SYSTEMS CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Riccardo Signorelli (Boston, Massachusetts); John J. Cooley (Boston, Massachusetts); Christopher John Sibbald Deane (Boston, Massachusetts); James Epstein (Sharon, Massachusetts); Padmanaban Sasthan Kuttipillai (Malden, Massachusetts); Fabrizio Martini (Boston, Massachusetts); Lindsay A. Wilhelmus (Lexington, Kentucky) |
| ABSTRACT | Disclosed herein is a method for fabricating an ultracapacitor, the method comprising disposing an energy storage cell comprising energy storage media within a housing; and constructing the ultracapacitor to operate within a temperature range between about 80 degrees Celsius to about 210 degrees Celsius. |
| FILED | Tuesday, September 20, 2022 |
| APPL NO | 17/948585 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/14 (20130101) Original (OR) Class H01G 11/18 (20130101) H01G 11/32 (20130101) H01G 11/58 (20130101) H01G 11/60 (20130101) H01G 11/78 (20130101) H01G 11/84 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901169 | Elam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); INCOM, INC. (Charlton, Massachusetts) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); INCOM, INC. (Charlton, Massachusetts) |
| INVENTOR(S) | Jeffrey W. Elam (Elmhurst, Illinois); Anil U. Mane (Naperville, Illinois); Mark Popecki (Durham, New Hampshire); Michael Minot (Andover, Massachusetts) |
| ABSTRACT | A secondary electron emissive layer resistant to infiltration and fouling. A barrier layer is formed by atomic layer deposition. The barrier layer may be an emissive layer and/or an interlayer. The barrier layer may form an interlayer that is a part of an electron amplifier positioned between an emissive layer and a resistive layer. The barrier layer is resistive to fluorine migration from either the emissive layer or the resistive layer. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/671135 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45527 (20130101) C23C 16/45553 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 9/42 (20130101) H01J 9/125 (20130101) Original (OR) Class H01J 40/04 (20130101) H01J 40/16 (20130101) H01J 43/246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901470 | Sewell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Maxeon Solar Pte. Ltd. (Singapore, Singapore) |
| ASSIGNEE(S) | Maxeon Solar Pte. Ltd. (Singapore, Singapore) |
| INVENTOR(S) | Richard Hamilton Sewell (Los Altos, California); Matthieu Minault Reich (San Jose, California); Andrea R. Bowring (Mountain View, California); Arbaz Shakir (Santa Clara, California); Ryan Reagan (Hayward, California); Matthew Matsumoto (Pasadena, California) |
| ABSTRACT | Wire-based metallization and stringing techniques for solar cells, and the resulting solar cells, modules, and equipment, are described. In an example, a string of solar cells includes a plurality of back-contact solar cells, wherein each of the plurality of back-contact solar cells includes P-type and N-type doped diffusion regions. A plurality of conductive wires is disposed over a back surface of each of the plurality of solar cells, wherein each of the plurality of conductive wires is substantially parallel to the P-type and N-type doped diffusion regions of each of the plurality of solar cells. One or more of the plurality of conductive wires adjoins a pair of adjacent solar cells of the plurality of solar cells and has a relief feature between the pair of adjacent solar cells. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/032975 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/188 (20130101) H01L 31/0504 (20130101) Original (OR) Class H01L 31/0516 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901476 | Pan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MICROLINK DEVICES, INC. (Niles, Illinois) |
| ASSIGNEE(S) | MICROLINK DEVICES, INC. (Niles, Illinois) |
| INVENTOR(S) | Noren Pan (Wilmette, Illinois); Glen Hillier (Spring Grove, Illinois); Duy Phach Vu (San Jose, California); Rao Tatavarti (Mount Prospect, Illinois); Christopher Youtsey (Libertyville, Illinois); David McCallum (West Chicago, Illinois); Genevieve Martin (Chicago, Illinois) |
| ABSTRACT | The present invention utilizes epitaxial lift-off in which a sacrificial layer is included in the epitaxial growth between the substrate and a thin film III-V compound solar cell. To provide support for the thin film III-V compound solar cell in absence of the substrate, a backing layer is applied to a surface of the thin film III-V compound solar cell before it is separated from the substrate. To separate the thin film III-V compound solar cell from the substrate, the sacrificial layer is removed as part of the epitaxial lift-off. Once the substrate is separated from the thin film III-V compound solar cell, the substrate may then be reused in the formation of another thin film III-V compound solar cell. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170133 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/1844 (20130101) H01L 31/1852 (20130101) Original (OR) Class H01L 31/1896 (20130101) H01L 31/06875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901550 | Yao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Zhenpeng Yao (Skokie, Illinois); Christopher M. Wolverton (Wilmette, Illinois) |
| ABSTRACT | Calcium ion batteries are provided. The calcium ion batteries include a cathode, an alloying anode composed of one or more intermetallic calcium compounds in electrical communication with the cathode; and an electrolyte disposed between the anode and the cathode. The intermetallic calcium compounds are intermetallic compounds of calcium and transition metals and metalloids. |
| FILED | Tuesday, October 22, 2019 |
| APPL NO | 17/287459 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Alloys C22C 24/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/381 (20130101) Original (OR) Class H01M 10/054 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901835 | Nojima |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| ASSIGNEE(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| INVENTOR(S) | Geraldo Nojima (Fort Mill, South Carolina) |
| ABSTRACT | An apparatus, such as a power converter, includes first, second and third core bus plates arranged in parallel. The apparatus also includes a first bus extension plate joined to the first core bus plate and extending therefrom at a first angle and a second bus extension plate joined to the second core bus plate and extending therefrom at a second angle. The apparatus further includes a third bus extension plated joined with the third core bus plate and disposed parallel to the first bus extension plate and a fourth bus extension plate joined with the third core bus plate and disposed parallel to the second bus extension plate. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/358303 |
| ART UNIT | 2841 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/003 (20130101) Original (OR) Class H02M 7/797 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 5/04 (20130101) H05K 5/0021 (20130101) H05K 5/0247 (20130101) H05K 7/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901859 | Otanicar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Tulsa (Tulsa, Oklahoma) |
| ASSIGNEE(S) | The University of Tulsa (Tulsa, Oklahoma) |
| INVENTOR(S) | Todd Otanicar (Tulsa, Oklahoma); Matthew Orosz (Cambridge, Massachusetts) |
| ABSTRACT | A photovoltaic retrofit device for a concentrating solar thermal power plant having a parabolic trough reflector, and a fluid receiver with working fluid therein spaced from the reflector and positioned at a focal point of the reflector. The photovoltaic device includes a plurality of adjustable angle dichroic mirrors positioned between the parabolic trough reflector and the fluid receiver. A photovoltaic receiver assembly has multiple photovoltaic panels in angular relationship to each other. A photovoltaic temperature regulating system includes a fluid medium to regulate temperature of the photovoltaic panels. |
| FILED | Thursday, March 07, 2019 |
| APPL NO | 16/295647 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 23/74 (20180501) F24S 2023/872 (20180501) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/30 (20141201) H02S 40/22 (20141201) H02S 40/44 (20141201) Original (OR) Class H02S 40/425 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11902150 | Roweth |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Duncan Roweth (Bristol, United Kingdom) |
| ABSTRACT | System and methods are described for providing adaptive routing in the presence of persistent flows. Switches in a fabric have the capability to establish flow channels. Switches can adaptively route flows, while monitoring transmission characteristics of the flows channels to identify whether any flows are experiencing congestion towards a destination. In response to detecting congestion, it can be further determined whether the flow is related to a source of congestion, or alternative the flow is a victim of congestion. Flows that are a source of congestion have their routing constrained to prevent congestion from propagating. For example, new packets of a flow that is a source of congestion may be forced to only take the path of the data transmission that detected said congestion (preventing congestion from spreading). Alternatively, victims of congestion do not have their routing constrained, and packets can take any path as permitted by adaptive routing. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/594721 |
| ART UNIT | 2478 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11902318 | Rivera et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Joshua Eli Rivera (Thornton, Colorado); Vivek Kumar Singh (Ames, Iowa); Evan Vladislav Michael Vaughan (Golden, Colorado); Adarsh Hasandka (Lakewood, Colorado); Joshua Van Natta (Denver, Colorado); Bruno Mauricio Salvatico (Golden, Colorado) |
| ABSTRACT | The present disclosure is related to a cyber-security system that includes a Supervisory Control and Data Acquisition (SCADA) network monitor configured to receive a data set from a power system network, an event manager, and a mitigation system, where the SCADA network monitor includes an anomaly detector. |
| FILED | Tuesday, October 13, 2020 |
| APPL NO | 17/069320 |
| ART UNIT | 2495 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/554 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1425 (20130101) H04L 63/1441 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D1014583 | Pino |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Ruben Arturo Pino (Kansas City, Missouri) |
| ABSTRACT | |
| FILED | Wednesday, December 29, 2021 |
| APPL NO | 29/821387 |
| ART UNIT | 2915 — Design |
| CURRENT CPC | Machines not elsewhere specified D15/122 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D1014584 | Pino |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Ruben Arturo Pino (Kansas City, Missouri) |
| ABSTRACT | |
| FILED | Monday, August 28, 2023 |
| APPL NO | 29/901046 |
| ART UNIT | 2915 — Design |
| CURRENT CPC | Machines not elsewhere specified D15/122 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11896031 | Gibbons et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE SOUTH DAKOTA BOARD OF REGENTS, AS GOVERNING BOARD FOR SOUTH DAKOTA STATE UNIVERSITY (Pierre, South Dakota) |
| ASSIGNEE(S) | The South Dakota Board of Regent, as Governing Board for South Dakota State University (Pierre, South Dakota) |
| INVENTOR(S) | William Gibbons (Brookings, South Dakota); Michael Brown (Volga, South Dakota) |
| ABSTRACT | The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 17/581535 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 1/14 (20130101) A23J 1/125 (20130101) Original (OR) Class A23J 1/148 (20130101) Fodder A23K 10/14 (20160501) A23K 10/38 (20160501) A23K 20/147 (20160501) A23K 40/20 (20160501) A23K 40/25 (20160501) A23K 50/80 (20160501) Technologies for Adaptation to Climate Change Y02A 40/818 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896676 | Steinmetz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California); Sourabh Shukla (Cleveland, Ohio) |
| ABSTRACT | A pepino mosaic virus (PepMV) carrier comprising a PepMV particle that has been modified to carry an imaging agent or anticancer agent is described. The PepMV carrier can be used in a method of targeting cancer cells and tissue by administering it to a subject. Cancer tissue targeted by the PepMV carrier can be imaged using an imaging agent, or treated using an anticancer agent. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988210 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 47/6901 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896735 | Kumta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Prashant N. Kumta (Pittsburgh, Pennsylvania); Jingyao Wu (Pittsburgh, Pennsylvania); Oleg Velikokhatnyi (Pittsburgh, Pennsylvania) |
| ABSTRACT | The invention includes compositions including magnesium-lithium alloys containing various alloying elements for medical implant devices. The devices are constructed of the compositions or have applied thereto a coating formed therefrom. Within the structure of the magnesium-lithium alloy, there is a co-existence of alpha and beta phases. The invention also includes methods of preparing the magnesium-lithium alloys and articles, such as medical implant devices, for use in medical applications, including orthopedic, dental, craniofacial and cardiovascular surgery. |
| FILED | Wednesday, July 21, 2021 |
| APPL NO | 17/381445 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/30 (20130101) Original (OR) Class A61L 27/047 (20130101) A61L 27/54 (20130101) A61L 27/306 (20130101) A61L 31/16 (20130101) A61L 31/022 (20130101) A61L 31/082 (20130101) A61L 31/088 (20130101) A61L 2300/102 (20130101) Alloys C22C 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11896741 | Rabolt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John F. Rabolt (Greenville, Delaware); Liang Gong (Newark, Delaware); D. Bruce Chase (Newark, Delaware); Isao Noda (Fairfield, Ohio); Brian Sobieski (Newark, Delaware) |
| ASSIGNEE(S) | UNIVERSITY OF DELAWARE (Newark, Delaware) |
| INVENTOR(S) | John F. Rabolt (Greenville, Delaware); Liang Gong (Newark, Delaware); D. Bruce Chase (Newark, Delaware); Isao Noda (Fairfield, Ohio); Brian Sobieski (Newark, Delaware) |
| ABSTRACT | Disclosed herein is a device comprising a PHA based copolymer layer comprising at least one of an electrospun ribbon of fibers of a polyhydroxyalkanoate based copolymer or the polarized polymeric composition obtained by the process of claim 1, wherein the layer is configured to exhibit one or more of a piezoelectric effect, a pyroelectric effect and a ferroelectric effect, wherein each of the electrospun ribbon of fibers and the polarized polymeric composition comprises a β-form of the PHA based copolymer present in an amount of from about 10% to about 99%, as measured by x-ray diffraction. The device can be configured for use as a sensor, a actuator, a nanomotor, or a biobattery. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/578214 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0215 (20130101) A61B 5/1473 (20130101) A61B 5/6876 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) A61B 2562/12 (20130101) A61B 2562/029 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/06 (20130101) A61L 31/14 (20130101) Original (OR) Class A61L 2400/12 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14276 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/37512 (20170801) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/00 (20130101) C08J 2367/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/84 (20130101) Electric solid-state devices not otherwise provided for H10N 30/20 (20230201) H10N 30/045 (20230201) H10N 30/098 (20230201) H10N 30/302 (20230201) H10N 30/857 (20230201) H10N 30/1061 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897036 | Vakil et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Parth Nalin Vakil (Tallahassee, Florida); Geoffrey F. Strouse (Tallahassee, Florida) |
| ABSTRACT | Methods of forming metal multipod nanostructures. The methods may include providing a mixture that includes a metal acetylacetonate, a reducing agent, and a carboxylic acid. The mixture may be contacted with microwaves to form the metal multipod nanostructures. The methods may offer control over the structure and/or morphology of the metal multipod nanostructures. |
| FILED | Monday, October 03, 2022 |
| APPL NO | 17/937634 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/054 (20220101) B22F 1/056 (20220101) B22F 1/0545 (20220101) B22F 1/0545 (20220101) B22F 1/0553 (20220101) B22F 1/0553 (20220101) B22F 1/0553 (20220101) B22F 9/24 (20130101) Original (OR) Class B22F 9/24 (20130101) B22F 2003/1054 (20130101) B22F 2202/11 (20130101) B22F 2301/15 (20130101) B22F 2301/25 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Alloys C22C 1/0433 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897129 | Simaan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Nabil Simaan (Nashville, Tennessee); Giuseppe Del Giudice (Nashville, Tennessee); Long Wang (Nashville, Tennessee); Karen M. Joos (Nashville, Tennessee); Jin-Hui Shen (Nashville, Tennessee) |
| ABSTRACT | A robotic system, such as a continuum robot, that includes at least one hollow tube backbone and an equilibrium modulation wire at least partially positioned within the backbone. The robotic system is configured to adjust a position of an end effector by bending the hollow tube and to further adjust the position of the robotic device by adjusting a linear insertion position of the equilibrium modulation wire inside the hollow tube, wherein adjusting the linear insertion position of the equilibrium modulation wire changes a flexural rigidity of the hollow tube resulting in a change in the resulting bending angle of the robotic device. |
| FILED | Friday, February 26, 2021 |
| APPL NO | 17/187534 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/0009 (20130101) B25J 9/065 (20130101) Original (OR) Class B25J 9/104 (20130101) B25J 9/123 (20130101) B25J 9/161 (20130101) B25J 9/1625 (20130101) B25J 9/1635 (20130101) B25J 18/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897140 | Wandzel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Arthur Richard Wandzel (Orchard Lake, Michigan); Stefanie Tellex (Providence, Rhode Island) |
| ABSTRACT | A system and method of operating a mobile robot to perform tasks includes representing a task in an Object-Oriented Partially Observable Markov Decision Process model having at least one belief pertaining to a state and at least one observation space within an environment, wherein the state is represented in terms of classes and objects and each object has at least one attribute and a semantic label. The method further includes receiving a language command identifying a target object and a location corresponding to the target object, updating the belief associated with the target object based on the language command, driving the mobile robot to the observation space identified in the updated belief, searching the updated observation space for each instance of the target object, and providing notification upon completing the task. In an embodiment, the task is a multi-object search task. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 17/280365 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1661 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897479 | Beal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania); BUCKNELL UNIVERSITY (Lewisburg, Pennsylvania) |
| INVENTOR(S) | Craig E. Beal (Lewisburg, Pennsylvania); Sean N. Brennan (State College, Pennsylvania) |
| ABSTRACT | A device for estimating a friction coefficient between a road surface and an automotive tire through determination of a steering torque during a steering maneuver of a slow-rolling or stationary vehicle includes a computer configured for constructing a brush model for a description of the steering torque across a contact patch between the tire and road surface. The steering torque is a torque acting on a steering axis required to overcome resistance to tire twisting on the road surface at a wheel velocity and a steering rate. The steering torque depends on a tire brush vertical load distribution and relative motion of tire brushes and the road surface. The device further includes sensors for measuring the wheel velocity and the steering rate and mechanism for measurements or estimation of the steering torque. The friction coefficient is estimated based on the measurements or estimation of the steering torque and the brush model. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 17/441787 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 40/13 (20130101) B60W 40/068 (20130101) Original (OR) Class B60W 40/101 (20130101) B60W 2040/1384 (20130101) B60W 2420/10 (20130101) B60W 2510/202 (20130101) B60W 2520/28 (20130101) B60W 2540/18 (20130101) B60W 2552/40 (20200201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897764 | Groves et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | John T. Groves (Princeton, New Jersey); Roy Xiao (Princeton, New Jersey) |
| ABSTRACT | Methods, kits, cartridges, and compounds related to generating chlorine dioxide by exposing ClO2− to at least one of an iron porphyrin catalyst or an iron porphyrazine catalyst are described. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550448 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/18 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/26 (20130101) B01J 31/183 (20130101) B01J 31/1815 (20130101) B01J 31/2295 (20130101) B01J 2531/025 (20130101) B01J 2531/842 (20130101) Non-metallic Elements; Compounds Thereof; C01B 11/024 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/76 (20130101) C02F 2103/023 (20130101) C02F 2303/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/025 (20130101) Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor D21C 9/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897822 | Noe-Hays et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Abraham Noe-Hays (Putney, Vermont); Nancy G. Love (Ann Arbor, Michigan) |
| ABSTRACT | A system for generating a concentrated product from a feedstock includes a reciprocating concentration system that includes first and second chambers to which the feedstock is alternately provided and from which the concentrated product is alternately removed, and a heat transfer system in thermal communication with the first and second chambers, the heat transfer system being configured to reversibly transfer heat between the first and second chambers such that the first chamber alternates between melting a frozen portion of the feedstock in the second chamber and having a frozen portion of the feedstock in the first chamber melted by the feedstock in the second chamber. The system further includes a heat dump system in thermal communication with the reciprocating concentration system, the heat dump system being configured to remove heat from the reciprocating concentration system. |
| FILED | Monday, November 09, 2020 |
| APPL NO | 17/093123 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 9/0013 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/10 (20130101) Nitrogenous Fertilisers C05C 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897893 | Isaacs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Lyle David Isaacs (Silver Spring, Maryland); Volker Briken (Laurel, Maryland); Gaya Hettiarachchi (Arlington, Virginia); Da Ma (Carrboro, North Carolina); Duc M. Nguyen (Miami, Florida) |
| ABSTRACT | Acyclic CB[n]-type compounds, methods of making such compounds, and uses of the compounds. For example, these compounds can be used as nanocontainers to solubilize pharmaceutical agents. Also provided are compositions and methods of using them for therapy or prophylaxis of a wide variety of conditions for which therapy or prophylaxis is desirable. |
| FILED | Monday, December 14, 2020 |
| APPL NO | 17/121241 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/122 (20130101) A61K 31/787 (20130101) A61K 47/22 (20130101) Heterocyclic Compounds C07D 487/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898021 | Shan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wanliang Shan (Jamesville, New York) |
| ASSIGNEE(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
| INVENTOR(S) | Wanliang Shan (Jamesville, New York) |
| ABSTRACT | A variety of polymeric composites with tunable mechanical stiffness and electrical conductivity are claimed herein. For example, the composite may have an elastomeric matrix, a plurality of tunable particles, and a plurality of conductive fibers embedded in the matrix. The composites may also be a tunable foam matrix and an elastomeric matrix. In some embodiments, the composites are a low melting point alloy (LMPA) foam infiltrated by an elastomer, whose stiffness can be tuned by more than two orders of magnitude through external heating. In other embodiments, the composite may be a conductive particle-fiber-matrix three-component composite capable of changing its elastic rigidity rapidly and reversibly when powered with electrical current. |
| FILED | Friday, January 03, 2020 |
| APPL NO | 16/733462 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 7/90 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/68 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2083/00 (20130101) B29K 2307/04 (20130101) B29K 2505/00 (20130101) B29K 2705/10 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/0085 (20130101) Original (OR) Class C08J 2203/06 (20130101) C08J 2383/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/08 (20130101) C08K 7/06 (20130101) C08K 9/10 (20130101) C08K 2003/0862 (20130101) C08K 2201/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898055 | Kumta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Prashant N. Kumta (Pittsburgh, Pennsylvania); Sangeetha Kunjukunju (Pittsburgh, Pennsylvania); Nicole J. Ostrowski (Pittsburgh, Pennsylvania); Abhijit Roy (Pittsburgh, Pennsylvania); Boeun Lee (Pittsburgh, Pennsylvania); Madhumati Ramanathan (Hillsboro, Oregon) |
| ABSTRACT | The invention relates to polyelectrolyte multilayer coatings and, methods for their preparation and application to substrates to enhance the bioactivity and corrosion protection of the substrates' surface. The invention is particularly suitable for coating substrates employed for medical applications, such as but not limited to medical implant devices for drug and/or biologics delivery in a patient. The substrate has a positive or negative charge. The polyelectrolyte multilayer coatings include at least a first polymer layer and a second polymer layer. The first polymer and second polymer have opposite charges. Each of the polymer layers is individually applied using a layer-by-layer such that an alternating charge multilayer coating is formed. |
| FILED | Wednesday, October 06, 2021 |
| APPL NO | 17/495543 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) A61F 2210/0076 (20130101) A61F 2310/00976 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/04 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 2300/608 (20130101) A61L 2420/08 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 7/58 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 105/04 (20130101) C09D 167/04 (20130101) C09D 177/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899014 | Cornish et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Virginia Wood Cornish (New York, New York); Nili Ostrov (Brookline, Massachusetts); Miguel Jimenez (Winthrop, Massachusetts); Sonja Billerbeck (Groningen, Netherlands) |
| ABSTRACT | The present invention provides sensor cells comprising a receptor that binds to an analyte indicative of the presence of an agent, where binding of the analyte to the receptor triggers a detection event that is indicative of the presence of the agent. In certain embodiments, the detection event is appearance of a reporter detectable by the naked eye. The present invention also provides uses of such sensor cells for detecting the presence of an agent in a sample. |
| FILED | Friday, June 19, 2020 |
| APPL NO | 16/906669 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/005 (20130101) C12Q 1/06 (20130101) C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/566 (20130101) Original (OR) Class G01N 33/569 (20130101) G01N 33/5023 (20130101) G01N 33/5038 (20130101) G01N 33/5695 (20130101) G01N 33/56911 (20130101) G01N 33/56916 (20130101) G01N 33/56961 (20130101) G01N 2333/726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11899335 | Leuenberger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Michael N. Leuenberger (Orlando, Florida); Muhammad Waqas Shabbir (Orlando, Florida) |
| ABSTRACT | An IR source may also include an electrically conductive layer defining a back contact. The IR source may also include a first dielectric layer over the electrically conductive layer, a transparent electrically conductive layer over the first dielectric layer, and a second dielectric layer over the transparent electrically conductive layer. The IR source may include a graphene layer over the second dielectric layer and having a perforated pattern, a protective layer over the graphene layer, and first and second electrically conductive contacts coupled to the graphene layer. The graphene layer may be configured to emit IR radiation when a voltage signal is applied between the first and second electrically conductive contacts. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/444087 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/292 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11900624 | Pau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Stanley Pau (Tucson, Arizona); Rongguang Liang (Tucson, Arizona) |
| ABSTRACT | Methods and systems are described that enable three-dimensional (3D) imaging of objects. One example system includes a light source that produces multiple light beams having specific spectral content and polarization states. The system also includes phase masks that modify the intensity or phase of the light, and projection optics that allow simultaneously projection of at least three fringe patterns onto an object having particular phase, polarization and spectral characteristics. The detection system includes a camera that simultaneously receives light associated with the at the fringe patterns upon reflection from the object, and a processing unit coupled to the camera unit that determines one or both of a phase or a depth information associated with the object. The system and associated methods can efficiency produce 2D images of the object and allow determination of characteristics such as surface profile. The disclosed systems and methods can be effectively implemented with moving objects. |
| FILED | Monday, March 13, 2023 |
| APPL NO | 18/183005 |
| ART UNIT | 2614 — Recording and Compression |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/25 (20130101) Image Data Processing or Generation, in General G06T 7/521 (20170101) Original (OR) Class G06T 17/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901473 | Burger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Tobias Burger (Ann Arbor, Michigan); Byungjun Lee (Ann Arbor, Michigan); Dejiu Fan (Ann Arbor, Michigan); Andrej Lenert (Ann Arbor, Michigan); Stephen R. Forrest (Ann Arbor, Michigan) |
| ABSTRACT | To reach high efficiencies, thermophotovoltaic cells must utilize the broad spectrum of a radiative thermal source. One promising approach to overcome this challenge is to have low-energy photons reflected and reabsorbed by the thermal emitter, where their energy can have another chance at contributing toward photogeneration in the cell. However, current methods for photon recuperation are limited by insufficient bandwidth or parasitic absorption, resulting in large efficiency losses relative to theoretical limits. This work demonstrates nearly perfect reflection of low-energy photons (˜99%) by embedding an air layer within the TPV cell. This result represents a four-fold reduction in parasitic absorption relative to existing TPV cells. As out-of-band reflectance approaches unity, TPV efficiency becomes nearly insensitive to cell bandgap and emitter temperature. Accessing this regime unlocks a range of possible materials and heat sources that were previously inaccessible to TPV energy conversion. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232243 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/04 (20130101) C30B 25/22 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/043 (20141201) H01L 31/0264 (20130101) H01L 31/0687 (20130101) Original (OR) Class H01L 31/0735 (20130101) H01L 31/1852 (20130101) H01L 31/1896 (20130101) H01L 31/02327 (20130101) H01L 33/0093 (20200501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11897140 | Wandzel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Arthur Richard Wandzel (Orchard Lake, Michigan); Stefanie Tellex (Providence, Rhode Island) |
| ABSTRACT | A system and method of operating a mobile robot to perform tasks includes representing a task in an Object-Oriented Partially Observable Markov Decision Process model having at least one belief pertaining to a state and at least one observation space within an environment, wherein the state is represented in terms of classes and objects and each object has at least one attribute and a semantic label. The method further includes receiving a language command identifying a target object and a location corresponding to the target object, updating the belief associated with the target object based on the language command, driving the mobile robot to the observation space identified in the updated belief, searching the updated observation space for each instance of the target object, and providing notification upon completing the task. In an embodiment, the task is a multi-object search task. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 17/280365 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1661 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898907 | Lewis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Tewksbury, Massachusetts) |
| INVENTOR(S) | Benjamin James Lewis (Redondo Beach, California) |
| ABSTRACT | A spectrometer is configured to form a spectrally resolved image of electromagnetic radiation from an electromagnetic radiation source. The spectrometer can include an optical guide device configured to guide electromagnetic radiation along an optical path. The optical guide device can include a first prism positioned in the optical path. The optical guide device can further include a focusing optic. The first prism can include at least one freeform prism surface that comprises at least some degree of cylindrical curvature having freeform polynomial terms formed thereon, which surface can be a substantially cylindrical, a substantially acylindrical, or a substantially flat surface having freeform polynomial terms formed thereon. |
| FILED | Monday, September 19, 2022 |
| APPL NO | 17/948153 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/04 (20130101) G01J 3/18 (20130101) G01J 3/0208 (20130101) Original (OR) Class G01J 3/2823 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898911 | Jovanovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); OBSERVATOIRE DE LA COTE D'AZUR (Nice, France) |
| INVENTOR(S) | Nemanja Jovanovic (Sierra Madre, California); Jeffrey B. Jewell (Pasadena, California); Pradip R. Gatkine (Pasadena, California); Gautam Vasisht (Pasadena, California); Charles A. Beichman (Pasadena, California); Nick Cvetojevic (Nice, France) |
| ABSTRACT | A photonic integrated circuit including an input for receiving input electromagnetic radiation having a bandwidth greater than 60 nm; a spectral splitter splitting the electromagnetic radiation into a plurality of spectral channels; a modulator for modulating an amplitude and a phase of one or more of the spectral channels so as to form modulated outputs; and a spectral recombiner for combining the modulated outputs into a single output port outputting output electromagnetic radiation having the desired output spectral intensity profile shaped by and synthesized from the modulated outputs. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/958097 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/12 (20130101) G01J 3/28 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) G02F 1/225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11902078 | Barsoum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Constellation Designs, LLC (Wayne, Pennsylvania) |
| ASSIGNEE(S) | Constellation Designs, LLC (Wayne, Pennsylvania) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use signal constellations, which have unequally spaced (i.e. ‘geometrically’ shaped) points. In many embodiments, the communication systems use specific geometric constellations that are capacity optimized at a specific SNR. In addition, ranges within which the constellation points of a capacity optimized constellation can be perturbed and are still likely to achieve a given percentage of the optimal capacity increase compared to a constellation that maximizes dmin, are also described. Capacity measures that are used in the selection of the location of constellation points include, but are not limited to, parallel decode (PD) capacity and joint capacity. |
| FILED | Monday, May 24, 2021 |
| APPL NO | 17/328993 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 14/023 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11897983 | Bolskar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TDA Research, Inc (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Robert Donald Bolskar (Arvada, Colorado); James William Raebiger (Golden, Colorado); Rhia M Martin (Arvada, Colorado); Silvia De Vito Luebben (Golden, Colorado) |
| ABSTRACT | Crosslink-forming monomers, comprising reverse-acrylate groups, and crosslinked polymer networks formed by the polymerization of monomers that comprise said reverse-acrylate crosslink-forming monomers. Crosslink-forming monomers, comprising reverse-acrylate groups, comprising an alkyl, an aryl, an alkoxyl, and an alkylamino group bridging one or more reverse-acrylate groups. Crosslink-forming monomers, comprising reverse-acrylate groups, comprising an alkyl, an aryl, an alkoxyl, and an alkylamino ester groups. Crosslink-forming monomers, comprising reverse-acrylate groups, comprising alkyl groups where the group is selected from the group consisting of a methyl, an ethyl, a propyl, an n-butyl and a t-butyl. Reverse-acrylate crosslink-forming monomers comprise a chemical structure where the two or more polymerizable carbon-carbon double bonds are connected by a crosslinking group on the opposite side of the hydrolysable ester groups relative to normal crosslinking acrylate monomers. The crosslink-forming monomers herein form crosslinked polymer networks that do not lose their crosslinking upon hydrolysis of the ester linkages. |
| FILED | Tuesday, March 16, 2021 |
| APPL NO | 17/203648 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 222/1025 (20200201) Original (OR) Class C08F 2438/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11898919 | Sotoudeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intelligent Fiber Optic Systems Corporation (San Jose, California) |
| ASSIGNEE(S) | Intelligent Fiber Optic Systems Corporation (Fremont, California) |
| INVENTOR(S) | Vahid Sotoudeh (Los Altos, California); Behzad Moslehi (Los Altos, California); Joshua Kuehn (Boulder Creek, California); Richard J. Black (Menlo Park, California) |
| ABSTRACT | A temperature correcting pressure gauge which has a diaphragm having at least one surface coupled to a source of pressure to be measured, the diaphragm first surface having a first FBG from a first optical fiber attached in an appropriately sensitive region of the diaphragm, a FBG from a second optical fiber attached to the opposite surface from the first FBG, the first and second FBGs reflecting or transmitting optical energy of decreasing or increasing wavelength, respectively, in response to an applied pressure. The first and second FBGs have nominal operating wavelength ranges that are adjacent to each other but are exclusive ranges and the FBGs also have closely matched pressure coefficients and temperature coefficients. |
| FILED | Thursday, November 04, 2021 |
| APPL NO | 17/518598 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/3206 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/246 (20130101) Original (OR) Class G01L 1/2281 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11901097 | Majkic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas); AMPEERS LLC (Houston, Texas) |
| INVENTOR(S) | Goran Majkic (Houston, Texas); Anis Ben Yahia (Houston, Texas); Wenbo Luo (Houston, Texas); Venkat Selvamanickam (Houston, Texas); Soumen Kar (Houston, Texas) |
| ABSTRACT | A round superconductor wire and method for fabricating same are disclosed. Embodiments are directed to a round superconductor wire including at least two superconductor tapes wound on a wire former. Each superconductor tape includes: bottom stabilizer and silver layers; substrate disposed above the bottom silver layer; buffer film stack disposed above the substrate; superconductor film disposed above the buffer film stack; top silver layer disposed above the superconductor film; and top stabilizer layer disposed above the top silver layer. At least one of the bottom stabilizer layer, bottom silver layer, substrate, buffer film stack, superconductor film, top silver layer, or top stabilizer layer is of a different width, thickness, or material composition in one of the superconductor tapes than in another of the superconductor tapes. These and other embodiments achieve a round superconductor wire having improved current density in high magnetic field applications when made in small diameters. |
| FILED | Monday, October 28, 2019 |
| APPL NO | 17/288838 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 12/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11899406 | Maurice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Vincent Maurice (Boulder, Colorado); Douglas G. Bopp (Boulder, Colorado) |
| ABSTRACT | Disclosed herein are devices, systems, and methods for fabricating alkali vapor cells. The methods disclosed herein comprise depositing a fluid into a reservoir of a device, the device comprising: a reservoir, a set of receptacles, and a set of conduits fluidly connecting each of the receptacles to the reservoir; such that, when a fluid is placed in the reservoir, the fluid flows to each of the receptacles via capillary action. Also disclosed herein are methods comprising flowing a fluid from an inlet to an outlet of a lumen of a main conduit of a device, the device further comprising a set of receptacles, each of the receptacles being in fluid communication with the lumen of the main conduit; such that, when a fluid flows from the inlet to the outlet through the lumen of the main conduit, the fluid further flows into each of the receptacles via capillary action. |
| FILED | Thursday, January 07, 2021 |
| APPL NO | 17/143483 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/02 (20130101) Apparatus or Tools Specially Designed for Making or Maintaining Clocks or Watches G04D 3/0069 (20130101) Original (OR) Class Time-interval Measuring G04F 5/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE49835 | Almeida et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America, as represented by the Secretary of Commerce, NIST (Gaithersburg, Maryland) |
| ASSIGNEE(S) | United States of America as Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Jamie L Almeida (Gaithersburg, Maryland); Kenneth D. Cole (Gaithersburg, Maryland) |
| ABSTRACT | A multiplex polymerase chain reaction assay that targets nine tetranucleotide short tandem repeat (STR) markers in the mouse genome. Unique profiles were obtained from seventy-two mouse samples that were used to determine the allele distribution for each STR marker. Correlations between allele fragment length and repeat number were determined with DNA Sanger sequencing. Genotypes for L929 and NIH3T3 cell lines were shown to be stable with increasing passage numbers as there were no significant differences in fragment length with samples of low passage when compared to high passage samples. In order to detect cell line contaminants, primers for two human STR markers were incorporated into the multiplex assay to facilitate detection of human and African green monkey DNA. This multiplex assay is the first of its kind to provide a unique STR profile for each individual mouse sample and can be used to authenticate mouse cell lines. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263835 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11900749 | Hastings et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | William Hastings (Billings, Montana); James Gilkeson (Alexandria, Virginia); Douglas MacIvor (Arlington, Virginia) |
| ABSTRACT | Various embodiments of the present invention are directed toward systems and methods relating to security screening. For example, a screening system includes a chamber configured to accommodate a user to be screened, and a chamber scanner. The chamber scanner is configured to scan the user to identify whether the user is carrying an undivested item that needs to be divested. The chamber is configured to release the user to proceed from the chamber to a secure area, upon confirmation that no undivested items are to be divested. |
| FILED | Thursday, February 02, 2023 |
| APPL NO | 18/105055 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/0041 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/28 (20200101) Original (OR) Class Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11902416 | Vemury |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | Systems and methods for secure distribution of biometric matching processing are provided. Certain configurations include homomorphic encrypting of captured biometric information. In some configurations, the biometric information is classified without decryption between a first identity class and a second identity class. The biometric information may be formed as a feature vector. A homomorphic encrypted feature vector may be formed by homomorphic encrypting of the biometric information. |
| FILED | Tuesday, December 13, 2022 |
| APPL NO | 18/080294 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) Original (OR) Class H04L 9/3231 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11896349 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Nathaniel Braman (Bethel Park, Pennsylvania) |
| ABSTRACT | Embodiments discussed herein facilitate determination of a response to treatment and/or a prognosis for a tumor based at least in part on features of tumor-associated vasculature (TAV). One example embodiment is a method, comprising: accessing a medical imaging scan of a tumor, wherein the tumor is segmented on the medical imaging scan; segmenting tumor-associated vasculature (TAV) associated with the tumor based on the medical imaging scan; extracting one or more features from the TAV; providing the one or more features extracted from the TAV to a trained machine learning model; and receiving, from the machine learning model, one of a predicted response to a treatment for the tumor or a prognosis for the tumor. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116319 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/004 (20130101) A61B 5/08 (20130101) A61B 5/0035 (20130101) A61B 5/02007 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/12 (20170101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20036 (20130101) G06T 2207/20081 (20130101) G06T 2207/30061 (20130101) G06T 2207/30068 (20130101) G06T 2207/30096 (20130101) G06T 2207/30101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11897950 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Augusta University Research Institute, Inc. (Augusta, Georgia); Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Kebin Liu (Augusta, Georgia); John Klement (Augusta, Georgia); Priscilla S. Redd (Augusta, Georgia) |
| ABSTRACT | Antibodies and antigen binding fragments thereof that immunospecifically bind OPN (OPN) and inhibit OPN activity are provided herein. The disclosed antibodies and antigen binding fragments are useful for modulating signal transduction through OPN proteins. The antibodies and antigen-binding fragments are useful for the treatment or prevention of cancer, osteoporosis, or other immune diseases. |
| FILED | Friday, December 04, 2020 |
| APPL NO | 17/112098 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/24 (20130101) Original (OR) Class C07K 2317/565 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 11898830 | Vabnick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federal Bureau of Investigation (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by The Federal Bureau of Investigation, Department of Justice (Washington, District of Columbia) |
| INVENTOR(S) | Ian B. Vabnick (Fredericksburg, Virginia) |
| ABSTRACT | Provided are methods and related devices for disrupting an explosive device using a propellant driven disrupter (PDD) that propels a rounded projectile (RP) toward an explosive device. The RP travels along a linear trajectory and impacts the target, including a barrier portion of the explosive device. The impacting between the RP and barrier forms a composite projectile via a solid state weld between a portion of the barrier and the RP distal end, thereby minimizing or avoiding spall and fragment generation into the explosive device. The projectile traverses a penetration distance along the linear trajectory, or a defined-angle relative thereto, to disrupt the explosive device without unwanted explosive detonation. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/862940 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/02 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/76 (20130101) F42B 12/745 (20130101) F42B 33/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11902150 | Roweth |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Duncan Roweth (Bristol, United Kingdom) |
| ABSTRACT | System and methods are described for providing adaptive routing in the presence of persistent flows. Switches in a fabric have the capability to establish flow channels. Switches can adaptively route flows, while monitoring transmission characteristics of the flows channels to identify whether any flows are experiencing congestion towards a destination. In response to detecting congestion, it can be further determined whether the flow is related to a source of congestion, or alternative the flow is a victim of congestion. Flows that are a source of congestion have their routing constrained to prevent congestion from propagating. For example, new packets of a flow that is a source of congestion may be forced to only take the path of the data transmission that detected said congestion (preventing congestion from spreading). Alternatively, victims of congestion do not have their routing constrained, and packets can take any path as permitted by adaptive routing. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/594721 |
| ART UNIT | 2478 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Nuclear Regulatory Commission (NRC)
| US 11897784 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| INVENTOR(S) | Ge Yang (Raleigh, North Carolina); Zheng Zhang (Raleigh, North Carolina) |
| ABSTRACT | In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to compound Bi-poor perovskite crystals, methods for making the same, and ionizing and other electromagnetic radiation detectors constructed using the Bi-poor perovskite crystals. The Bi-poor perovskite crystals can be synthesized using melt-based growth methods and solution-based growth methods and contain no toxic heavy metals such as lead, cadmium, thallium, or mercury. Devices fabricated from the crystals maintain acceptable levels of performance over time. In some aspects, post-growth annealing can be used to improve the properties, including, but not limited to, room temperature resistivity and response to radiation. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 17/644886 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 29/006 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) C01P 2002/72 (20130101) C01P 2002/74 (20130101) C01P 2002/77 (20130101) C01P 2002/88 (20130101) C01P 2004/02 (20130101) C01P 2006/40 (20130101) C01P 2006/80 (20130101) C01P 2006/90 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7435 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) C30B 29/12 (20130101) Measurement of Nuclear or X-radiation G01T 1/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 13, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
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APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
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3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
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The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
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